From 2a10fb618957c228e5c830817c9f37ea1f7ad5de Mon Sep 17 00:00:00 2001 From: Anita Caron Date: Fri, 13 Oct 2023 17:17:22 +0100 Subject: [PATCH 1/2] import OMO terms --- docs/odk-workflows/RepositoryFileStructure.md | 1 + src/ontology/Makefile | 17 +- src/ontology/imports/merged_import.owl | 116054 +-------------- src/ontology/imports/omo_terms.txt | 3 + src/ontology/uberon-odk.yaml | 2 + 5 files changed, 203 insertions(+), 115874 deletions(-) create mode 100644 src/ontology/imports/omo_terms.txt diff --git a/docs/odk-workflows/RepositoryFileStructure.md b/docs/odk-workflows/RepositoryFileStructure.md index b55918861f..aaea0d9af9 100644 --- a/docs/odk-workflows/RepositoryFileStructure.md +++ b/docs/odk-workflows/RepositoryFileStructure.md @@ -28,6 +28,7 @@ These are the current imports in UBERON | ncbitaxon | http://purl.obolibrary.org/obo/ncbitaxon/subsets/taxslim.owl | None | | nbo | http://purl.obolibrary.org/obo/nbo.owl | None | | orcidio | https://w3id.org/orcidio/orcidio.owl | None | +| omo | http://purl.obolibrary.org/obo/omo.owl | mirror | ## Components Components, in contrast to imports, are considered full members of the ontology. This means that any axiom in a component is also included in the ontology base - which means it is considered _native_ to the ontology. While this sounds complicated, consider this: conceptually, no component should be part of more than one ontology. If that seems to be the case, we are most likely talking about an import. Components are often not needed for ontologies, but there are some use cases: diff --git a/src/ontology/Makefile b/src/ontology/Makefile index 3951dcad80..4b6ff97250 100644 --- a/src/ontology/Makefile +++ b/src/ontology/Makefile @@ -114,7 +114,7 @@ all_main: $(MAIN_FILES) # ---------------------------------------- -IMPORTS = pr cl go envo ro bspo chebi pato bfo ncbitaxon nbo orcidio +IMPORTS = pr cl go envo ro bspo chebi pato bfo ncbitaxon nbo orcidio omo IMPORT_ROOTS = $(IMPORTDIR)/merged_import IMPORT_OWL_FILES = $(foreach n,$(IMPORT_ROOTS), $(n).owl) @@ -339,6 +339,12 @@ $(IMPORTDIR)/%_import.owl: $(MIRRORDIR)/merged.owl $(IMPORTDIR)/%_terms_combined .PRECIOUS: $(IMPORTDIR)/%_import.owl +## Module for ontology: omo + +$(IMPORTDIR)/omo_import.owl: $(MIRRORDIR)/merged.owl $(IMPORTDIR)/omo_terms_combined.txt + if [ $(IMP) = true ]; then $(ROBOT) merge -i $< query --update ../sparql/preprocess-module.ru --update ../sparql/inject-subset-declaration.ru --update ../sparql/inject-synonymtype-declaration.ru --update ../sparql/postprocess-module.ru \ + $(ANNOTATE_CONVERT_FILE); fi + .PHONY: refresh-imports refresh-imports: @@ -504,6 +510,15 @@ mirror-orcidio: | $(TMPDIR) if [ $(MIR) = true ] && [ $(IMP) = true ]; then $(ROBOT) convert -I https://w3id.org/orcidio/orcidio.owl -o $@.tmp.owl &&\ mv $@.tmp.owl $(TMPDIR)/$@.owl; fi + +## ONTOLOGY: omo +.PHONY: mirror-omo +.PRECIOUS: $(MIRRORDIR)/omo.owl +mirror-omo: | $(TMPDIR) + if [ $(MIR) = true ] && [ $(IMP) = true ]; then curl -L $(OBOBASE)/omo.owl --create-dirs -o $(MIRRORDIR)/omo.owl --retry 4 --max-time 200 &&\ + $(ROBOT) convert -i $(MIRRORDIR)/omo.owl -o $@.tmp.owl &&\ + mv $@.tmp.owl $(TMPDIR)/$@.owl; fi + ALL_MIRRORS = $(patsubst %, $(MIRRORDIR)/%.owl, $(IMPORTS)) MERGE_MIRRORS = true diff --git a/src/ontology/imports/merged_import.owl b/src/ontology/imports/merged_import.owl index 44bebed8e7..6ffe89ea3e 100644 --- a/src/ontology/imports/merged_import.owl +++ b/src/ontology/imports/merged_import.owl @@ -7,19 +7,9 @@ Prefix(rdfs:=) Ontology( - -Annotation(owl:versionInfo "2023-09-18") - -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) + +Annotation(owl:versionInfo "2023-10-13") + Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -31,127 +21,59 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -168,16 +90,10 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -188,9 +104,6 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -200,25 +113,17 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -229,93 +134,47 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -329,24 +188,16 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -354,87 +205,53 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -451,70 +268,34 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -527,37 +308,21 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -565,26 +330,12 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -593,87 +344,38 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -683,41 +385,18 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -725,77 +404,40 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -804,54 +446,30 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -873,32 +491,25 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -906,32 +517,27 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -942,16 +548,11 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -963,7 +564,6 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -974,15 +574,11 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -990,86 +586,59 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -1085,15 +654,12 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -1104,27 +670,18 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -1135,481 +692,148 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -1618,7 +842,6 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -1626,1041 +849,127 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -2677,257 +986,10 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -2941,343 +1003,80 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -3297,142 +1096,37 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -3444,2685 +1138,286 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -6133,3327 +1428,172 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -9463,8 +1603,6 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -9476,11 +1614,7 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -9987,7 +2121,6 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -9996,9 +2129,6 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -10011,8 +2141,6 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -10041,54 +2169,35 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -10103,14 +2212,10 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -10118,367 +2223,38 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -10648,6 +2424,7 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -11166,7 +2943,6 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -11218,6 +2994,7 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -11695,6 +3472,7 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -11723,6 +3501,7 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -11753,17 +3532,7 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) +Declaration(Class()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) @@ -11801,11 +3570,6 @@ Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) -Declaration(ObjectProperty()) -Declaration(ObjectProperty()) -Declaration(ObjectProperty()) -Declaration(ObjectProperty()) -Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) @@ -11831,7 +3595,6 @@ Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) -Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) @@ -11864,7 +3627,6 @@ Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) -Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) @@ -11898,16 +3660,11 @@ Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) -Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) -Declaration(ObjectProperty()) -Declaration(ObjectProperty()) -Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) -Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) @@ -11916,25 +3673,15 @@ Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) -Declaration(ObjectProperty()) Declaration(ObjectProperty()) -Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) -Declaration(ObjectProperty()) -Declaration(ObjectProperty()) -Declaration(ObjectProperty()) -Declaration(ObjectProperty()) -Declaration(ObjectProperty()) -Declaration(ObjectProperty()) -Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) -Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) @@ -11997,7 +3744,6 @@ Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) -Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) @@ -12008,10 +3754,6 @@ Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) -Declaration(ObjectProperty()) -Declaration(ObjectProperty()) -Declaration(ObjectProperty()) -Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) @@ -12021,9 +3763,6 @@ Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) -Declaration(ObjectProperty()) -Declaration(ObjectProperty()) -Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) @@ -12032,16 +3771,10 @@ Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) -Declaration(ObjectProperty()) -Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) -Declaration(ObjectProperty()) -Declaration(ObjectProperty()) Declaration(ObjectProperty()) -Declaration(ObjectProperty()) -Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) @@ -12055,12 +3788,10 @@ Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) -Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) -Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) @@ -12072,6 +3803,7 @@ Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) +Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) @@ -12079,9 +3811,12 @@ Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) +Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) +Declaration(AnnotationProperty()) +Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) @@ -12104,8 +3839,6 @@ Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) -Declaration(AnnotationProperty()) -Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) @@ -12119,7 +3852,6 @@ Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) -Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) @@ -12151,7 +3883,6 @@ Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) -Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) @@ -12164,22 +3895,24 @@ Declaration(AnnotationProperty() Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) -Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) -Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) +Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) +Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) +Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) +Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) @@ -12190,7 +3923,6 @@ Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) -Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) @@ -12207,13 +3939,10 @@ Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) -Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) -Declaration(AnnotationProperty()) -Declaration(AnnotationProperty()) Declaration(AnnotationProperty(rdfs:comment)) Declaration(AnnotationProperty(rdfs:label)) Declaration(AnnotationProperty(rdfs:seeAlso)) @@ -12222,63 +3951,167 @@ Declaration(AnnotationProperty() Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) +Declaration(Datatype(xsd:date)) ############################ # Annotation Properties ############################ # Annotation Property: (example of usage) +AnnotationAssertion( "example of usage"@en) +AnnotationAssertion( ) +AnnotationAssertion( "A phrase describing how a term should be used and/or a citation to a work which uses it. May also include other kinds of examples that facilitate immediate understanding, such as widely know prototypes or instances of a class, or cases where a relation is said to hold."@en) +AnnotationAssertion( "PERSON:Daniel Schober"@en) +AnnotationAssertion( "GROUP:OBI:"@en) AnnotationAssertion(rdfs:isDefinedBy ) AnnotationAssertion(rdfs:label "example of usage"@en) AnnotationAssertion(rdfs:label "example of usage") # Annotation Property: (definition) +AnnotationAssertion( "definition"@en) +AnnotationAssertion( ) +AnnotationAssertion( "The official definition, explaining the meaning of a class or property. Shall be Aristotelian, formalized and normalized. Can be augmented with colloquial definitions."@en) +AnnotationAssertion( "2012-04-05: +Barry Smith + +The official OBI definition, explaining the meaning of a class or property: 'Shall be Aristotelian, formalized and normalized. Can be augmented with colloquial definitions' is terrible. + +Can you fix to something like: + +A statement of necessary and sufficient conditions explaining the meaning of an expression referring to a class or property. + +Alan Ruttenberg + +Your proposed definition is a reasonable candidate, except that it is very common that necessary and sufficient conditions are not given. Mostly they are necessary, occasionally they are necessary and sufficient or just sufficient. Often they use terms that are not themselves defined and so they effectively can't be evaluated by those criteria. + +On the specifics of the proposed definition: + +We don't have definitions of 'meaning' or 'expression' or 'property'. For 'reference' in the intended sense I think we use the term 'denotation'. For 'expression', I think we you mean symbol, or identifier. For 'meaning' it differs for class and property. For class we want documentation that let's the intended reader determine whether an entity is instance of the class, or not. For property we want documentation that let's the intended reader determine, given a pair of potential relata, whether the assertion that the relation holds is true. The 'intended reader' part suggests that we also specify who, we expect, would be able to understand the definition, and also generalizes over human and computer reader to include textual and logical definition. + +Personally, I am more comfortable weakening definition to documentation, with instructions as to what is desirable. + +We also have the outstanding issue of how to aim different definitions to different audiences. A clinical audience reading chebi wants a different sort of definition documentation/definition from a chemistry trained audience, and similarly there is a need for a definition that is adequate for an ontologist to work with."@en) +AnnotationAssertion( "PERSON:Daniel Schober"@en) +AnnotationAssertion( "GROUP:OBI:"@en) AnnotationAssertion(rdfs:isDefinedBy ) AnnotationAssertion(rdfs:label "definition"@en) AnnotationAssertion(rdfs:label "definition") # Annotation Property: (editor note) +AnnotationAssertion( "editor note"@en) +AnnotationAssertion( ) +AnnotationAssertion( "An administrative note intended for its editor. It may not be included in the publication version of the ontology, so it should contain nothing necessary for end users to understand the ontology."@en) +AnnotationAssertion( "PERSON:Daniel Schober"@en) +AnnotationAssertion( "GROUP:OBI:"@en) AnnotationAssertion(rdfs:isDefinedBy ) AnnotationAssertion(rdfs:label "editor note"@en) AnnotationAssertion(rdfs:label "editor note") +# Annotation Property: (has obsolescence reason) + +AnnotationAssertion( "has obsolescence reason"@en) +AnnotationAssertion( "Relates an annotation property to an obsolescence reason. The values of obsolescence reasons come from a list of predefined terms, instances of the class obsolescence reason specification."@en) +AnnotationAssertion( "PERSON:Alan Ruttenberg"@en) +AnnotationAssertion( "PERSON:Melanie Courtot"@en) +AnnotationAssertion(rdfs:label "has obsolescence reason"@en) + # Annotation Property: (curator note) +AnnotationAssertion( "curator note"@en) +AnnotationAssertion( ) +AnnotationAssertion( "An administrative note of use for a curator but of no use for a user"@en) +AnnotationAssertion( "PERSON:Alan Ruttenberg"@en) AnnotationAssertion(rdfs:isDefinedBy ) AnnotationAssertion(rdfs:label "curator note"@en) AnnotationAssertion(rdfs:label "curator note") # Annotation Property: (term tracker item) +AnnotationAssertion( "term tracker item"@en) +AnnotationAssertion( "the URI for an OBI Terms ticket at sourceforge, such as https://sourceforge.net/p/obi/obi-terms/772/"@en) +AnnotationAssertion( ) +AnnotationAssertion( "An IRI or similar locator for a request or discussion of an ontology term."@en) +AnnotationAssertion( "Person: Jie Zheng, Chris Stoeckert, Alan Ruttenberg"@en) +AnnotationAssertion( "Person: Jie Zheng, Chris Stoeckert, Alan Ruttenberg"@en) AnnotationAssertion( "IAO:0000233") AnnotationAssertion( "external") AnnotationAssertion( "term_tracker_item") AnnotationAssertion( "true"^^xsd:boolean) AnnotationAssertion( "true"^^xsd:boolean) AnnotationAssertion( "term_tracker_item") +AnnotationAssertion(rdfs:comment "The 'tracker item' can associate a tracker with a specific ontology term."@en) +AnnotationAssertion(rdfs:label "term tracker item"@en) AnnotationAssertion(rdfs:label "term tracker item") # Annotation Property: (expand assertion to) +AnnotationAssertion( "expand assertion to"@en) +AnnotationAssertion( "ObjectProperty: RO??? +Label: spatially disjoint from +Annotations: expand_assertion_to \"DisjointClasses: (http://purl.obolibrary.org/obo/BFO_0000051 some ?X) (http://purl.obolibrary.org/obo/BFO_0000051 some ?Y)\" +"@en) +AnnotationAssertion( "A macro expansion tag applied to an annotation property which can be expanded into a more detailed axiom."@en) +AnnotationAssertion( "Chris Mungall"@en) +AnnotationAssertion(rdfs:label "expand assertion to"@en) AnnotationAssertion(rdfs:label "expand assertion to") -# Annotation Property: (preferred_root) +# Annotation Property: (has ontology root term) +AnnotationAssertion( "has ontology root term"@en) +AnnotationAssertion( "Ontology annotation property. Relates an ontology to a term that is a designated root term of the ontology. Display tools like OLS can use terms annotated with this property as the starting point for rendering the ontology class hierarchy. There can be more than one root."@en) +AnnotationAssertion( "Nicolas Matentzoglu"@en) AnnotationAssertion( "IAO:0000700") AnnotationAssertion( "external") AnnotationAssertion( "has_ontology_root_term") AnnotationAssertion( "true"^^xsd:boolean) AnnotationAssertion( "true"^^xsd:boolean) AnnotationAssertion( "has_ontology_root_term") +AnnotationAssertion(rdfs:label "has ontology root term"@en) AnnotationAssertion(rdfs:label "has ontology root term") AnnotationAssertion(rdfs:label "preferred_root") +# Annotation Property: (scheduled for obsoletion on or after) + +AnnotationAssertion( "scheduled for obsoletion on or after"@en) +AnnotationAssertion( "Used when the class or object is scheduled for obsoletion/deprecation on or after a particular date."@en) +AnnotationAssertion( "Chris Mungall, Jie Zheng"@en) +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/15532"@en) +AnnotationAssertion( "https://github.com/information-artifact-ontology/ontology-metadata/issues/32"@en) +AnnotationAssertion( "GO ontology"@en) +AnnotationAssertion(rdfs:label "scheduled for obsoletion on or after"@en) + # Annotation Property: (term replaced by) +AnnotationAssertion( "term replaced by"@en) +AnnotationAssertion( ) +AnnotationAssertion( "Use on obsolete terms, relating the term to another term that can be used as a substitute"@en) +AnnotationAssertion( "Person:Alan Ruttenberg"@en) +AnnotationAssertion( "Person:Alan Ruttenberg"@en) +AnnotationAssertion(rdfs:comment "Add as annotation triples in the granting ontology"@en) +AnnotationAssertion(rdfs:label "term replaced by"@en) AnnotationAssertion(rdfs:label "term replaced by") +# Annotation Property: (abbreviation) + +AnnotationAssertion( "CHEBI:26523 (reactive oxygen species) has an exact synonym (ROS), which is of type OMO:0003000 (abbreviation)") +AnnotationAssertion( "A synonym type for describing abbreviations or initalisms") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( "2023-03-03"^^xsd:date) +AnnotationAssertion(rdfs:label "abbreviation") + +# Annotation Property: (plural form) + +AnnotationAssertion( "CHEBI:23367 (molecular entity) has an exact synonym (molecular entities), which is of the type OMO:0003004 (plural form)") +AnnotationAssertion( "A synonym type for describing pluralization synonyms") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( "2023-03-03"^^xsd:date) +AnnotationAssertion(rdfs:label "plural form") +SubAnnotationPropertyOf( ) + # Annotation Property: (never in taxon) AnnotationAssertion( "tooth SubClassOf 'never in taxon' value 'Aves'") @@ -12433,14 +4266,6 @@ SubAnnotationPropertyOf( ) -# Annotation Property: () - -SubAnnotationPropertyOf( ) - -# Annotation Property: () - -SubAnnotationPropertyOf( ) - # Annotation Property: () SubAnnotationPropertyOf( ) @@ -12465,10 +4290,6 @@ SubAnnotationPropertyOf( ) -# Annotation Property: () - -SubAnnotationPropertyOf( ) - # Annotation Property: () SubAnnotationPropertyOf( ) @@ -12589,10 +4410,6 @@ SubAnnotationPropertyOf( ) -# Annotation Property: () - -SubAnnotationPropertyOf( ) - # Annotation Property: () SubAnnotationPropertyOf( ) @@ -12641,18 +4458,10 @@ SubAnnotationPropertyOf( ) -# Annotation Property: () - -SubAnnotationPropertyOf( ) - # Annotation Property: () SubAnnotationPropertyOf( ) -# Annotation Property: () - -SubAnnotationPropertyOf( ) - # Annotation Property: () SubAnnotationPropertyOf( ) @@ -12679,19 +4488,34 @@ AnnotationAssertion(rdfs:label (has_broad_synonym) +AnnotationAssertion( "An alternative label for a class or property which has a more general meaning than the preferred name/primary label.") +AnnotationAssertion( ) +AnnotationAssertion( "https://github.com/information-artifact-ontology/ontology-metadata/issues/18") +AnnotationAssertion(rdfs:label "has broad synonym"@en) AnnotationAssertion(rdfs:label "has_broad_synonym") +AnnotationAssertion(rdfs:seeAlso "https://github.com/information-artifact-ontology/ontology-metadata/issues/18") # Annotation Property: (database_cross_reference) AnnotationAssertion(rdfs:label "database_cross_reference") -# Annotation Property: (has_exact_synonym) +# Annotation Property: (has exact synonym) +AnnotationAssertion( "An alternative label for a class or property which has the exact same meaning than the preferred name/primary label.") +AnnotationAssertion( ) +AnnotationAssertion( "https://github.com/information-artifact-ontology/ontology-metadata/issues/20") +AnnotationAssertion(rdfs:label "has exact synonym"@en) AnnotationAssertion(rdfs:label "has_exact_synonym") +AnnotationAssertion(rdfs:seeAlso "https://github.com/information-artifact-ontology/ontology-metadata/issues/20") -# Annotation Property: (has_narrow_synonym) +# Annotation Property: (has narrow synonym) +AnnotationAssertion( "An alternative label for a class or property which has a more specific meaning than the preferred name/primary label.") +AnnotationAssertion( ) +AnnotationAssertion( "https://github.com/information-artifact-ontology/ontology-metadata/issues/19") +AnnotationAssertion(rdfs:label "has narrow synonym"@en) AnnotationAssertion(rdfs:label "has_narrow_synonym") +AnnotationAssertion(rdfs:seeAlso "https://github.com/information-artifact-ontology/ontology-metadata/issues/19") # Annotation Property: (has_obo_format_version) @@ -12703,7 +4527,12 @@ AnnotationAssertion(rdfs:label (has_related_synonym) +AnnotationAssertion( "An alternative label for a class or property that has been used synonymously with the primary term name, but the usage is not strictly correct.") +AnnotationAssertion( ) +AnnotationAssertion( "https://github.com/information-artifact-ontology/ontology-metadata/issues/21") +AnnotationAssertion(rdfs:label "has related synonym"@en) AnnotationAssertion(rdfs:label "has_related_synonym") +AnnotationAssertion(rdfs:seeAlso "https://github.com/information-artifact-ontology/ontology-metadata/issues/21") # Annotation Property: (has_scope) @@ -13221,39 +5050,6 @@ AnnotationAssertion( "preaxial to") TransitiveObjectProperty() -# Object Property: (has_not_completed) - -AnnotationAssertion(rdfs:label "has_not_completed") - -# Object Property: (lacks_part) - -AnnotationAssertion( "http://purl.obolibrary.org/obo/BFO_0000051 exactly 0 ?Y") -AnnotationAssertion(rdfs:label "lacks_part") - -# Object Property: (lacks_plasma_membrane_part) - -AnnotationAssertion( "http://purl.obolibrary.org/obo/BFO_0000051 exactly 0 (http://purl.obolibrary.org/obo/GO_0005886 and http://purl.obolibrary.org/obo/BFO_0000051 some ?Y)") -AnnotationAssertion(rdfs:label "lacks_plasma_membrane_part") - -# Object Property: (results in distribution of) - -AnnotationAssertion( "GOREL:0002003") -AnnotationAssertion( "external") -AnnotationAssertion( "results_in_distribution_of") -AnnotationAssertion( "results_in_distribution_of") -AnnotationAssertion(rdfs:label "results in distribution of") -AnnotationAssertion(rdfs:label "results_in_distribution_of") - -# Object Property: (results in fission of) - -AnnotationAssertion( "GOREL:0002004") -AnnotationAssertion( "external") -AnnotationAssertion( "results_in_fission_of") -AnnotationAssertion( "results_in_fission_of") -AnnotationAssertion(rdfs:label "results in fission of") -AnnotationAssertion(rdfs:label "results_in_fission_of") -SubObjectPropertyOf( ) - # Object Property: (characteristic of) AnnotationAssertion( "inheres in"@en) @@ -13616,16 +5412,6 @@ SubObjectPropertyOf( ) ObjectPropertyRange( ) -# Object Property: (occurs across) - -AnnotationAssertion( "A relationship between a process and a barrier, where the process occurs in a region spanning the barrier. For cellular processes the barrier is typically a membrane. Examples include transport across a membrane and membrane depolarization.") -AnnotationAssertion( ) -AnnotationAssertion( "2017-07-20T17:19:37Z"^^xsd:dateTime) -AnnotationAssertion( "RO:0002021") -AnnotationAssertion( "occurs_across") -AnnotationAssertion(rdfs:label "occurs across") -SubObjectPropertyOf( ) - # Object Property: (directly regulated by) AnnotationAssertion( ) @@ -14088,21 +5874,6 @@ SubObjectPropertyOf( ) TransitiveObjectProperty() -# Object Property: (expressed in) - -AnnotationAssertion( "'neural crest cell' SubClassOf expresses some 'Wnt1 gene'") -AnnotationAssertion( ) -AnnotationAssertion( "x expressed in y if and only if there is a gene expression process (GO:0010467) that occurs in y, and one of the following holds: (i) x is a gene, and x is transcribed into a transcript as part of the gene expression process (ii) x is a transcript, and the transcription of x is part of the gene expression process (iii) x is a mature gene product such as a protein, and x was translated or otherwise processes from a transcript that was transcribed as part of this gene expression process") -AnnotationAssertion( ) -AnnotationAssertion( "RO:0002206") -AnnotationAssertion( "expressed_in") -AnnotationAssertion(rdfs:label "expressed in"@en) -SubObjectPropertyOf( ) -InverseObjectProperties( ) -ObjectPropertyDomain( ) -ObjectPropertyDomain( ObjectUnionOf( )) -ObjectPropertyRange( ) - # Object Property: (directly develops from) AnnotationAssertion( ) @@ -14617,16 +6388,6 @@ AnnotationAssertion( "part of developmental precursor of"@en) SubObjectPropertyOf( ) -# Object Property: (expresses) - -AnnotationAssertion( ) -AnnotationAssertion( "y expresses x if and only if there is a gene expression process (GO:0010467) that occurs in y, and one of the following holds: (i) x is a gene, and x is transcribed into a transcript as part of the gene expression process (ii) x is a transcript, and x was transcribed from a gene as part of the gene expression process (iii) x is a mature gene product (protein or RNA), and x was translated or otherwise processed from a transcript that was transcribed as part of the gene expression process.") -AnnotationAssertion( ) -AnnotationAssertion( "RO:0002292") -AnnotationAssertion( "expresses") -AnnotationAssertion(rdfs:label "expresses"@en) -SubObjectPropertyOf( ) - # Object Property: (results in developmental progression of) AnnotationAssertion( ) @@ -14663,66 +6424,6 @@ AnnotationAssertion(rdfs:label "resu SubObjectPropertyOf( ) SubObjectPropertyOf( ) -# Object Property: (results in formation of) - -AnnotationAssertion( "every \"endocardial cushion formation\" (GO:0003272) results_in_formation_of some \"endocardial cushion\" (UBERON:0002062)"@en) -AnnotationAssertion( "an annotation of gene X to anatomical structure formation with results_in_formation_of UBERON:0000007 (pituitary gland) means that at the beginning of the process a pituitary gland does not exist and at the end of the process a pituitary gland exists.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "GOC:mtg_berkeley_2013") -AnnotationAssertion( "RO:0002297") -AnnotationAssertion( "external") -AnnotationAssertion( "results_in_formation_of") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "results_in_formation_of") -AnnotationAssertion(rdfs:label "results in formation of"@en) -AnnotationAssertion(rdfs:label "results in formation of") -SubObjectPropertyOf( ) -SubObjectPropertyOf( ) -InverseObjectProperties( ) - -# Object Property: (results in morphogenesis of) - -AnnotationAssertion( "tongue morphogenesis (GO:0043587) results in morphogenesis of tongue (UBERON:0001723)"@en) -AnnotationAssertion( "an annotation of gene X to cell morphogenesis with results_in_morphogenesis_of CL:0000540 (neuron) means that at the end of the process an input neuron has attained its shape.") -AnnotationAssertion( ) -AnnotationAssertion( "The relationship that links an entity with the process that results in the formation and shaping of that entity over time from an immature to a mature state.") -AnnotationAssertion( ) -AnnotationAssertion( "GOC:mtg_berkeley_2013") -AnnotationAssertion( "RO:0002298") -AnnotationAssertion( "external") -AnnotationAssertion( "results_in_morphogenesis_of") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "results_in_morphogenesis_of") -AnnotationAssertion(rdfs:label "results in morphogenesis of"@en) -AnnotationAssertion(rdfs:label "results in morphogenesis of") -SubObjectPropertyOf( ) -SubObjectPropertyOf( ) - -# Object Property: (results in maturation of) - -AnnotationAssertion( "bone maturation (GO:0070977) results_in_maturation_of bone (UBERON:0001474)"@en) -AnnotationAssertion( " an annotation of gene X to cell maturation with results_in_maturation_of CL:0000057 (fibroblast) means that the fibroblast is mature at the end of the process") -AnnotationAssertion( ) -AnnotationAssertion( "The relationship that links an entity with a process that results in the progression of the entity over time that is independent of changes in it's shape and results in an end point state of that entity.") -AnnotationAssertion( ) -AnnotationAssertion( "GOC:mtg_berkeley_2013") -AnnotationAssertion( "RO:0002299") -AnnotationAssertion( "external") -AnnotationAssertion( "results_in_maturation_of") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "results_in_maturation_of") -AnnotationAssertion(rdfs:label "results in maturation of"@en) -AnnotationAssertion(rdfs:label "results in maturation of") -SubObjectPropertyOf( ) -SubObjectPropertyOf( ) - # Object Property: (causally upstream of, positive effect) AnnotationAssertion( "p is causally upstream of, positive effect q iff p is casually upstream of q, and the execution of p is required for the execution of q.") @@ -14770,25 +6471,6 @@ AnnotationAssertion(rdfs:label "char AnnotationAssertion(rdfs:seeAlso ) SubObjectPropertyOf( ) -# Object Property: (results in acquisition of features of) - -AnnotationAssertion( "an annotation of gene X to cell differentiation with results_in_maturation_of CL:0000057 (fibroblast) means that at the end of the process the input cell that did not have features of a fibroblast, now has the features of a fibroblast.") -AnnotationAssertion( "The relationship that links a specified entity with the process that results in an unspecified entity acquiring the features and characteristics of the specified entity") -AnnotationAssertion( ) -AnnotationAssertion( "GOC:mtg_berkeley_2013") -AnnotationAssertion( "RO:0002315") -AnnotationAssertion( "external") -AnnotationAssertion( "results_in_acquisition_of_features_of") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "results_in_acquisition_of_features_of") -AnnotationAssertion(rdfs:label "results in acquisition of features of"@en) -AnnotationAssertion(rdfs:label "results in acquisition of features of") -SubObjectPropertyOf( ) -SubObjectPropertyOf( ) -ObjectPropertyRange( ) - # Object Property: (evolutionarily related to) AnnotationAssertion( "A relationship that holds via some environmental process") @@ -14877,17 +6559,6 @@ AnnotationAssertion( "part of structure that is capable of"@en) SubObjectPropertyOf( ) -# Object Property: (genomically related to) - -AnnotationAssertion( "holds between two entities when some genome-level process such as gene expression is involved. This includes transcriptional, spliceosomal events. These relations can be used between either macromolecule entities (such as regions of nucleic acid) or between their abstract informational counterparts.") -AnnotationAssertion( ) -AnnotationAssertion( "Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving the genome of an organism") -AnnotationAssertion( "RO:0002330") -AnnotationAssertion( "genomically_related_to") -AnnotationAssertion(rdfs:label "genomically related to"@en) -ObjectPropertyDomain( ) -ObjectPropertyRange( ) - # Object Property: (involved in) AnnotationAssertion( "c involved_in p if and only if c enables some process p', and p' is part of p") @@ -14901,23 +6572,6 @@ AnnotationAssertion(rdfs:seeAlso "ht SubObjectPropertyOf( ) SubObjectPropertyOf( ) -# Object Property: (regulates levels of) - -AnnotationAssertion( "every cellular sphingolipid homeostasis process regulates_level_of some sphingolipid") -AnnotationAssertion( "p regulates levels of c if p regulates some amount (PATO:0000070) of c") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "regulates levels of (process to entity)") -AnnotationAssertion( "RO:0002332") -AnnotationAssertion( "external") -AnnotationAssertion( "regulates_levels_of") -AnnotationAssertion( "regulates_levels_of") -AnnotationAssertion(rdfs:label "regulates levels of"@en) -AnnotationAssertion(rdfs:label "regulates levels of") -SubObjectPropertyOf( ) -ObjectPropertyDomain( ) -ObjectPropertyRange( ) - # Object Property: (enabled by) AnnotationAssertion( "inverse of enables") @@ -14973,98 +6627,6 @@ AnnotationAssertion(rdfs:label "posi AnnotationAssertion(rdfs:label "positively regulated by") SubObjectPropertyOf( ) -# Object Property: (related via localization to) - -AnnotationAssertion( "A relationship that holds via some process of localization") -AnnotationAssertion( ) -AnnotationAssertion( "Do not use this relation directly. It is a grouping relation.") -AnnotationAssertion( "RO:0002337") -AnnotationAssertion( "related_via_localization_to") -AnnotationAssertion(rdfs:label "related via localization to"@en) -ObjectPropertyDomain( ) -ObjectPropertyRange( ) - -# Object Property: (has target start location) - -AnnotationAssertion( "This relationship holds between p and l when p is a transport or localization process in which the outcome is to move some cargo c from some initial location l to some destination.") -AnnotationAssertion( ) -AnnotationAssertion( "RO:0002338") -AnnotationAssertion( "external") -AnnotationAssertion( "has_target_start_location") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "has_target_start_location") -AnnotationAssertion(rdfs:label "has target start location"@en) -AnnotationAssertion(rdfs:label "has target start location") -SubObjectPropertyOf( ) - -# Object Property: (has target end location) - -AnnotationAssertion( "This relationship holds between p and l when p is a transport or localization process in which the outcome is to move some cargo c from a an initial location to some destination l.") -AnnotationAssertion( ) -AnnotationAssertion( "RO:0002339") -AnnotationAssertion( "external") -AnnotationAssertion( "has_target_end_location") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "has_target_end_location") -AnnotationAssertion(rdfs:label "has target end location"@en) -AnnotationAssertion(rdfs:label "has target end location") -SubObjectPropertyOf( ) - -# Object Property: (results in transport along) - -AnnotationAssertion( "Holds between p and l when p is a transportation or localization process and the outcome of this process is to move c from one location to another, and the route taken by c follows a path that is aligned_with l ") -AnnotationAssertion( ) -AnnotationAssertion( "RO:0002341") -AnnotationAssertion( "external") -AnnotationAssertion( "results_in_transport_along") -AnnotationAssertion( "results_in_transport_along") -AnnotationAssertion(rdfs:label "results in transport along"@en) -AnnotationAssertion(rdfs:label "results in transport along") -SubObjectPropertyOf( ) - -# Object Property: (results in transport across) - -AnnotationAssertion( "Holds between p and m when p is a transportation or localization process and the outcome of this process is to move c from one location to another, and the route taken by c follows a path that crosses m.") -AnnotationAssertion( ) -AnnotationAssertion( "RO:0002342") -AnnotationAssertion( "external") -AnnotationAssertion( "results_in_transport_across") -AnnotationAssertion( ) -AnnotationAssertion( "results_in_transport_across") -AnnotationAssertion(rdfs:label "results in transport across"@en) -AnnotationAssertion(rdfs:label "results in transport across") -SubObjectPropertyOf( ) -SubObjectPropertyOf( ) - -# Object Property: (results in growth of) - -AnnotationAssertion( "'pollen tube growth' results_in growth_of some 'pollen tube'") -AnnotationAssertion( ) -AnnotationAssertion( "RO:0002343") -AnnotationAssertion( "external") -AnnotationAssertion( "results_in_growth_of") -AnnotationAssertion( "results_in_growth_of") -AnnotationAssertion(rdfs:label "results in growth of"@en) -AnnotationAssertion(rdfs:label "results in growth of") -SubObjectPropertyOf( ) -SubObjectPropertyOf( ) - -# Object Property: (results in transport to from or in) - -AnnotationAssertion( "'mitochondrial transport' results_in_transport_to_from_or_in some mitochondrion (GO:0005739)") -AnnotationAssertion( ) -AnnotationAssertion( "RO:0002344") -AnnotationAssertion( "external") -AnnotationAssertion( "results_in_transport_to_from_or_in") -AnnotationAssertion( "results_in_transport_to_from_or_in") -AnnotationAssertion(rdfs:label "results in transport to from or in"@en) -AnnotationAssertion(rdfs:label "results in transport to from or in") -SubObjectPropertyOf( ) - # Object Property: (member of) AnnotationAssertion( "An organism that is a member of a population of organisms") @@ -15117,14 +6679,6 @@ AnnotationAssertion(rdfs:label "outp SubObjectPropertyOf( ) SubObjectPropertyOf( ) -# Object Property: (formed as result of) - -AnnotationAssertion( ) -AnnotationAssertion( "RO:0002354") -AnnotationAssertion( "formed_as_result_of") -AnnotationAssertion(rdfs:label "formed as result of"@en) -SubObjectPropertyOf( ) - # Object Property: (attached to) AnnotationAssertion( "a is attached to b if and only if a and b are discrete objects or object parts, and there are physical connections between a and b such that a force pulling a will move b, or a force pulling b will move a") @@ -15887,21 +7441,6 @@ AnnotationAssertion( "molecular interaction relation helper property") SubObjectPropertyOf( ) -# Object Property: (results in movement of) - -AnnotationAssertion( "Holds between p and c when p is locomotion process and the outcome of this process is the change of location of c") -AnnotationAssertion( ) -AnnotationAssertion( "") -AnnotationAssertion( "RO:0002565") -AnnotationAssertion( "external") -AnnotationAssertion( "results_in_movement_of") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "results_in_movement_of") -AnnotationAssertion(rdfs:label "results in movement of") -SubObjectPropertyOf( ) - # Object Property: (causally influences) AnnotationAssertion( "The entity or characteristic A is causally upstream of the entity or characteristic B, A having an effect on B. An entity corresponds to any biological type of entity as long as a mass is measurable. A characteristic corresponds to a particular specificity of an entity (e.g., phenotype, shape, size).") @@ -16029,48 +7568,6 @@ AnnotationAssertion(rdfs:label "has SubObjectPropertyOf( ) SubObjectPropertyOf( ) -# Object Property: (results in breakdown of) - -AnnotationAssertion( "p results in breakdown of c if and only if the execution of p leads to c no longer being present at the end of p") -AnnotationAssertion( "RO:0002586") -AnnotationAssertion( "results_in_breakdown_of") -AnnotationAssertion(rdfs:label "results in breakdown of") -SubObjectPropertyOf( ) - -# Object Property: (results in assembly of) - -AnnotationAssertion( "RO:0002588") -AnnotationAssertion( "external") -AnnotationAssertion( "results_in_assembly_of") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "results_in_assembly_of") -AnnotationAssertion(rdfs:label "results in assembly of") -SubObjectPropertyOf( ) -SubObjectPropertyOf( ) - -# Object Property: (results in disassembly of) - -AnnotationAssertion( "RO:0002590") -AnnotationAssertion( "external") -AnnotationAssertion( "results_in_disassembly_of") -AnnotationAssertion( "results_in_disassembly_of") -AnnotationAssertion(rdfs:label "results in disassembly of") -SubObjectPropertyOf( ) -SubObjectPropertyOf( ) - -# Object Property: (results in organization of) - -AnnotationAssertion( "p results in organization of c iff p results in the assembly, arrangement of constituent parts, or disassembly of c") -AnnotationAssertion( "RO:0002592") -AnnotationAssertion( "external") -AnnotationAssertion( "results_in_organization_of") -AnnotationAssertion( "results_in_organization_of") -AnnotationAssertion(rdfs:label "results in organization of") -SubObjectPropertyOf( ) -SubObjectPropertyOf( ) - # Object Property: (causal relation between material entity and a process) AnnotationAssertion( "A relationship that holds between a material entity and a process in which causality is involved, with either the material entity or some part of the material entity exerting some influence over the process, or the process influencing some aspect of the material entity.") @@ -16192,47 +7689,6 @@ AnnotationAssertion(rdfs:label "prod ObjectPropertyDomain( ) ObjectPropertyRange( ) -# Object Property: (has primary input or output) - -AnnotationAssertion( "p 'has primary input ot output' c iff either (a) p 'has primary input' c or (b) p 'has primary output' c.") -AnnotationAssertion( ) -AnnotationAssertion( "2018-12-13T11:26:17Z"^^xsd:dateTime) -AnnotationAssertion( "RO:0004007") -AnnotationAssertion( "external") -AnnotationAssertion( "has_primary_input_or_output") -AnnotationAssertion( ) -AnnotationAssertion( "has_primary_input_or_output") -AnnotationAssertion(rdfs:label "has primary input or output") -SubObjectPropertyOf( ) - -# Object Property: (has primary output) - -AnnotationAssertion(Annotation( ) Annotation( "GOC:dph") Annotation( "GOC:kva") Annotation( "GOC:pt") Annotation(rdfs:comment "PMID:27812932") "p has primary output c if (a) p has output c and (b) the goal of process is to modify, produce, or transform c.") -AnnotationAssertion( ) -AnnotationAssertion( "2018-12-13T11:26:32Z"^^xsd:dateTime) -AnnotationAssertion( "RO:0004008") -AnnotationAssertion( "external") -AnnotationAssertion( "has_primary_output") -AnnotationAssertion( ) -AnnotationAssertion( "has_primary_output") -AnnotationAssertion(rdfs:label "has primary output") -SubObjectPropertyOf( ) -SubObjectPropertyOf( ) - -# Object Property: (has primary input) - -AnnotationAssertion(Annotation( ) Annotation( "GOC:dph") Annotation( "GOC:kva") Annotation( "GOC:pt") Annotation(rdfs:comment "PMID:27812932") "p has primary input c if (a) p has input c and (b) the goal of process is to modify, consume, or transform c.") -AnnotationAssertion( ) -AnnotationAssertion( "2018-12-13T11:26:56Z"^^xsd:dateTime) -AnnotationAssertion( "RO:0004009") -AnnotationAssertion( "external") -AnnotationAssertion( "has_primary_input") -AnnotationAssertion( ) -AnnotationAssertion( "has_primary_input") -AnnotationAssertion(rdfs:label "has primary input") -SubObjectPropertyOf( ) -SubObjectPropertyOf( ) - # Object Property: (enables subfunction) AnnotationAssertion( "Holds between an entity and an process P where the entity enables some larger compound process, and that larger process has-part P.") @@ -16328,37 +7784,6 @@ SubObjectPropertyOf( ) ObjectPropertyRange( ) -# Object Property: (acts on population of) - -AnnotationAssertion( "p acts on population of c iff c' is a collection, has members of type c, and p has participant c") -AnnotationAssertion( ) -AnnotationAssertion( "2020-06-08T17:21:33Z"^^xsd:dateTime) -AnnotationAssertion( "RO:0012003") -AnnotationAssertion( "external") -AnnotationAssertion( "acts_on_population_of") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "acts_on_population_of") -AnnotationAssertion(rdfs:label "acts on population of"@en) -AnnotationAssertion(rdfs:label "acts on population of") -SubObjectPropertyOf( ) - -# Object Property: (results in fusion of) - -AnnotationAssertion( ) -AnnotationAssertion( "2021-02-26T07:28:29Z"^^xsd:dateTime) -AnnotationAssertion( "RO:0012008") -AnnotationAssertion( "external") -AnnotationAssertion( "results_in_fusion_of") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "results_in_fusion_of") -AnnotationAssertion(rdfs:label "results in fusion of"@en) -AnnotationAssertion(rdfs:label "results in fusion of") -SubObjectPropertyOf( ) - # Object Property: (indirectly causally upstream of) AnnotationAssertion( "p is indirectly causally upstream of q iff p is causally upstream of q and there exists some process r such that p is causally upstream of r and r is causally upstream of q.") @@ -16391,26 +7816,6 @@ AnnotationAssertion( "has synaptic IO in region"@en) SubObjectPropertyOf( ) -# Object Property: (different in magnitude relative to) - -AnnotationAssertion(Annotation( "https://orcid.org/0000-0002-6601-2165") "q1 different_in_magnitude_relative_to q2 if and only if magnitude(q1) NOT =~ magnitude(q2). Here, magnitude(q) is a function that maps a quality to a unit-invariant scale.") -AnnotationAssertion( "RO:0015006") -AnnotationAssertion( "different_in_magnitude_relative_to") -AnnotationAssertion(rdfs:label "different in magnitude relative to") -ObjectPropertyDomain( ) -ObjectPropertyRange( ) - -# Object Property: (increased in magnitude relative to) - -AnnotationAssertion(Annotation( "https://orcid.org/0000-0002-6601-2165") "q1 increased_in_magnitude_relative_to q2 if and only if magnitude(q1) > magnitude(q2). Here, magnitude(q) is a function that maps a quality to a unit-invariant scale.") -AnnotationAssertion( "RO:0015007") -AnnotationAssertion( "increased_in_magnitude_relative_to") -AnnotationAssertion(rdfs:comment "This relation is used to determine the 'directionality' of relative qualities such as 'increased strength', relative to the parent type, 'strength'.") -AnnotationAssertion(rdfs:label "increased in magnitude relative to") -SubObjectPropertyOf( ) -ObjectPropertyDomain( ) -ObjectPropertyRange( ) - # Object Property: (has cross section) AnnotationAssertion(Annotation( "https://orcid.org/0000-0002-6601-2165") "s3 has_cross_section s3 if and only if : there exists some 2d plane that intersects the bearer of s3, and the impression of s3 upon that plane has shape quality s2.") @@ -16419,30 +7824,6 @@ AnnotationAssertion( "Example: a spherical object has the quality of being spherical, and the spherical quality has_cross_section round.") AnnotationAssertion(rdfs:label "has cross section") -# Object Property: (has high plasma membrane amount) - -AnnotationAssertion( "'Ly-76 high positive erythrocyte' equivalent to 'enucleate erythrocyte' and (has_high_plasma_membrane_amount some 'lymphocyte antigen 76 (mouse)')") -AnnotationAssertion(Annotation( "PMID:19243617") "A relation between a cell and molecule or complex such that every instance of the cell has a high number of instances of that molecule expressed on the cell surface.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "RO:0015015") -AnnotationAssertion( "has_high_plasma_membrane_amount") -AnnotationAssertion(rdfs:label "has high plasma membrane amount") -SubObjectPropertyOf( ) -ObjectPropertyDomain( ) - -# Object Property: (has low plasma membrane amount) - -AnnotationAssertion( "'DN2b thymocyte' equivalent to 'DN2 thymocyte' and (has_low_plasma_membrane_amount some 'mast/stem cell growth factor receptor')") -AnnotationAssertion(Annotation( "PMID:19243617") "A relation between a cell and molecule or complex such that every instance of the cell has a low number of instances of that molecule expressed on the cell surface.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "RO:0015016") -AnnotationAssertion( "has_low_plasma_membrane_amount") -AnnotationAssertion(rdfs:label "has low plasma membrane amount") -SubObjectPropertyOf( ) -ObjectPropertyDomain( ) - # Object Property: (device utilizes material) AnnotationAssertion( "A diagnostic testing device utilizes a specimen.") @@ -16508,10 +7889,6 @@ SubObjectPropertyOf( "by_means"@en) -# Object Property: (has_participant) - -AnnotationAssertion(rdfs:label "has_participant"@en) - ############################ @@ -16600,7 +7977,6 @@ AnnotationAssertion(rdfs:label "ind SubClassOf( ) SubClassOf( ObjectAllValuesFrom( )) DisjointClasses( ) -DisjointClasses( ) # Class: (spatial region) @@ -16715,7 +8091,6 @@ AnnotationAssertion(rdfs:isDefinedBy "specifically dependent continuant"@en) SubClassOf( ) SubClassOf( ObjectAllValuesFrom( )) -DisjointClasses( ) # Class: (role) @@ -16734,24 +8109,8 @@ AnnotationAssertion(Annotation( ) "(forall (x) (if (Role x) (RealizableEntity x))) // axiom label in BFO2 CLIF: [061-001] ") AnnotationAssertion(rdfs:isDefinedBy ) AnnotationAssertion(rdfs:label "role"@en) -EquivalentClasses( ) SubClassOf( ) -# Class: (generically dependent continuant) - -AnnotationAssertion( "gdc") -AnnotationAssertion( "GenericallyDependentContinuant") -AnnotationAssertion( "The entries in your database are patterns instantiated as quality instances in your hard drive. The database itself is an aggregate of such patterns. When you create the database you create a particular instance of the generically dependent continuant type database. Each entry in the database is an instance of the generically dependent continuant type IAO: information content entity."@en) -AnnotationAssertion( "the pdf file on your laptop, the pdf file that is a copy thereof on my laptop"@en) -AnnotationAssertion( "the sequence of this protein molecule; the sequence that is a copy thereof in that protein molecule."@en) -AnnotationAssertion(Annotation( ) "b is a generically dependent continuant = Def. b is a continuant that g-depends_on one or more other entities. (axiom label in BFO2 Reference: [074-001])"@en) -AnnotationAssertion(Annotation( ) "(iff (GenericallyDependentContinuant a) (and (Continuant a) (exists (b t) (genericallyDependsOnAt a b t)))) // axiom label in BFO2 CLIF: [074-001] ") -AnnotationAssertion(rdfs:comment "A continuant that is dependent on one or other independent continuant bearers. For every instance of A requires some instance of (an independent continuant type) B but which instance of B serves can change from time to time."@en) -AnnotationAssertion(rdfs:isDefinedBy ) -AnnotationAssertion(rdfs:label "generically dependent continuant"@en) -SubClassOf( ) -SubClassOf( ObjectAllValuesFrom( )) - # Class: (function) AnnotationAssertion( "function") @@ -16841,38 +8200,6 @@ AnnotationAssertion( "electron") SubClassOf( ) -# Class: (steroid aldehyde) - -AnnotationAssertion( "Any steroid substituted by a formyl group.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "steroid aldehydes") -AnnotationAssertion( "CHEBI:131565") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "steroid aldehyde") -SubClassOf( ) -SubClassOf( ) - -# Class: (Mycoplasma genitalium metabolite) - -AnnotationAssertion( "Any bacterial metabolite produced during a metabolic reaction in Mycoplasma genitalium.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "Mycoplasma genitalium metabolites") -AnnotationAssertion( "CHEBI:131604") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "Mycoplasma genitalium metabolite") -SubClassOf( ) - -# Class: (C19-steroid) - -AnnotationAssertion( "A steroid compound with a structure based on a 19-carbon (androstane) skeleton.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "C19-steroids") -AnnotationAssertion( "CHEBI:131621") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "C19-steroid") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (dicarboxylic acids and O-substituted derivatives) AnnotationAssertion( "A class of carbonyl compound encompassing dicarboxylic acids and any derivatives obtained by substitution of either one or both of the carboxy hydrogens.") @@ -16898,33 +8225,6 @@ SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (3-oxo-Delta(4)-steroid group) - -AnnotationAssertion( "An organic group derived from any 3-oxo-Delta(4)-steroid.") -AnnotationAssertion( "0") -AnnotationAssertion( "C6H6O") -AnnotationAssertion( "94.111") -AnnotationAssertion( "94.04186") -AnnotationAssertion( "C1=C(C*)*C(CC1=O)*") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "UniProt") "a 3-oxo-Delta4-steroid group") -AnnotationAssertion( "CHEBI:136849") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "3-oxo-Delta(4)-steroid group") -SubClassOf( ) - -# Class: (5beta steroid) - -AnnotationAssertion( "Any steroid that has beta-configuration at position 5.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "5beta steroids") -AnnotationAssertion(Annotation( "ChEBI") "5beta-steroid") -AnnotationAssertion(Annotation( "ChEBI") "5beta-steroids") -AnnotationAssertion( "CHEBI:136889") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "5beta steroid") -SubClassOf( ) - # Class: (inorganic acid) AnnotationAssertion( "A Bronsted acid derived from one or more inorganic compounds. Inorganic acids (also known as mineral acids) form hydrons and conjugate base ions when dissolved in water.") @@ -16938,17 +8238,6 @@ AnnotationAssertion( "inorganic acid") SubClassOf( ) -# Class: (bile acids) - -AnnotationAssertion( "Any member of a group of hydroxy steroids occuring in bile, where they are present as the sodium salts of their amides with glycine or taurine. In mammals bile acids almost invariably have 5beta-configuration, while in lower vertebrates, some bile acids, known as allo-bile acids, have 5alpha-configuration.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion( "CHEBI:138366") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "bile acids") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - # Class: (apoprotein) AnnotationAssertion( "An apoprotein is a protein devoid of its characteristic prosthetic group or metal.") @@ -17016,45 +8305,6 @@ AnnotationAssertion(rdfs:label "car SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (alpha-hydroxy ketone) - -AnnotationAssertion( "An alpha-oxyketone that has a hydroxy group as the alpha-oxy moiety.") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:15326516") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:19908854") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:20382022") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:23295224") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "alpha-hydroxy ketones") -AnnotationAssertion(Annotation( "ChEBI") "alpha-hydroxy-ketone") -AnnotationAssertion(Annotation( "ChEBI") "alpha-hydroxy-ketones") -AnnotationAssertion(Annotation( "ChEBI") "alpha-hydroxyketone") -AnnotationAssertion(Annotation( "ChEBI") "alpha-hydroxyketones") -AnnotationAssertion( "CHEBI:139588") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "alpha-hydroxy ketone") -SubClassOf( ) -SubClassOf( ) - -# Class: (primary alpha-hydroxy ketone) - -AnnotationAssertion( "An alpha-hydroxy ketone in which the carbonyl group and the hydroxy group are linked by a -CH2 (methylene) group.") -AnnotationAssertion( "0") -AnnotationAssertion( "C2H3O2R") -AnnotationAssertion( "59.044") -AnnotationAssertion( "59.01330") -AnnotationAssertion( "*C(C(O)([H])[H])=O") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "primary alpha-hydroxy ketones") -AnnotationAssertion(Annotation( "ChEBI") "primary alpha-hydroxy-ketone") -AnnotationAssertion(Annotation( "ChEBI") "primary alpha-hydroxy-ketones") -AnnotationAssertion(Annotation( "ChEBI") "primary alpha-hydroxyketone") -AnnotationAssertion(Annotation( "ChEBI") "primary alpha-hydroxyketones") -AnnotationAssertion( "CHEBI:139590") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "primary alpha-hydroxy ketone") -SubClassOf( ) -SubClassOf( ) - # Class: (secondary carboxamide) AnnotationAssertion( "A carboxamide resulting from the formal condensation of a carboxylic acid with a primary amine; formula RC(=O)NHR(1).") @@ -17070,21 +8320,6 @@ AnnotationAssertion( "secondary carboxamide") SubClassOf( ) -# Class: (fatty acid 4:0) - -AnnotationAssertion( "Any saturated fatty acid containing 4 carbons.") -AnnotationAssertion( "0") -AnnotationAssertion( "CHO2R") -AnnotationAssertion( "45.017") -AnnotationAssertion( "44.99765") -AnnotationAssertion( "*C(O)=O") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion( "CHEBI:140601") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "fatty acid 4:0") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (24G7 epitope) AnnotationAssertion( "An antigenic epitope recognized by an anti-bilirubin monoclonal antibody designated 24G7. A substructure of bilirubin IXalpha, it is the region containing the oxo group at C-1, the methyl group at C-2, C-(4, 5, 6, 9), and N-21 and -22.") @@ -17100,48 +8335,6 @@ AnnotationAssertion(rdfs:label "24 SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (purines D-ribonucleoside) - -AnnotationAssertion( "A purine ribonucleoside that is a purine derivative attached to a beta-D-ribofuranosyl residue at position 9 via a glycosidic (N-glycosyl) linkage.") -AnnotationAssertion( "0") -AnnotationAssertion( "C10H11N4O4R2") -AnnotationAssertion( "251.219") -AnnotationAssertion( "251.07803") -AnnotationAssertion( "C1(=*)NC(=NC2=C1N=CN2[C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)*") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "UniProt") "a purine D-ribonucleoside") -AnnotationAssertion( "CHEBI:142355") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "purines D-ribonucleoside") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (glutamate(1-)) - -AnnotationAssertion( "An alpha-amino-acid anion that is the conjugate base of glutamic acid, having anionic carboxy groups and a cationic amino group") -AnnotationAssertion( "-1") -AnnotationAssertion( "C5H8NO4") -AnnotationAssertion( "InChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/p-1") -AnnotationAssertion( "WHUUTDBJXJRKMK-UHFFFAOYSA-M") -AnnotationAssertion( "146.12136") -AnnotationAssertion( "146.04588") -AnnotationAssertion( "[NH3+]C(CCC([O-])=O)C([O-])=O") -AnnotationAssertion(Annotation( "Gmelin") "Gmelin:327908") -AnnotationAssertion(Annotation( "JCBN") "glutamate(1-)") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "hydrogen glutamate") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "IUPAC") "2-ammoniopentanedioate") -AnnotationAssertion(Annotation( "UniProt") "glutamate") -AnnotationAssertion(Annotation( "JCBN") "glutamic acid monoanion") -AnnotationAssertion( "CHEBI:14321") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "glutamate(1-)") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (acceptor) AnnotationAssertion( "A molecular entity that can accept an electron, a pair of electrons, an atom or a group from another molecular entity.") @@ -17238,339 +8431,6 @@ SubClassOf( ObjectSomeValuesFrom( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (acetylcholine) - -AnnotationAssertion( "Actylcholine is an ester of acetic acid and choline, which acts as a neurotransmitter.") -AnnotationAssertion( "+1") -AnnotationAssertion( "C7H16NO2") -AnnotationAssertion( "InChI=1S/C7H16NO2/c1-7(9)10-6-5-8(2,3)4/h5-6H2,1-4H3/q+1") -AnnotationAssertion( "OIPILFWXSMYKGL-UHFFFAOYSA-N") -AnnotationAssertion( "146.20748") -AnnotationAssertion( "146.11756") -AnnotationAssertion( "CC(=O)OCC[N+](C)(C)C") -AnnotationAssertion( "CHEBI:12686") -AnnotationAssertion( "CHEBI:13715") -AnnotationAssertion( "CHEBI:22197") -AnnotationAssertion( "CHEBI:2416") -AnnotationAssertion( "CHEBI:40559") -AnnotationAssertion(Annotation( "ChemIDplus") "Beilstein:1764436") -AnnotationAssertion(Annotation( "ChemIDplus") "CAS:51-84-3") -AnnotationAssertion(Annotation( "KEGG COMPOUND") "CAS:51-84-3") -AnnotationAssertion( "DrugBank:DB03128") -AnnotationAssertion(Annotation( "DrugCentral") "Drug_Central:65") -AnnotationAssertion(Annotation( "Gmelin") "Gmelin:326108") -AnnotationAssertion( "KEGG:C01996") -AnnotationAssertion( "LINCS:LSM-5888") -AnnotationAssertion( "PDBeChem:ACH") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:14764638") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:15014918") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:15231705") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:15361288") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:18050502") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:18407448") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:19255787") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:20963497") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:21130809") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:21246223") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:21545631") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:21601579") -AnnotationAssertion( "Wikipedia:Acetylcholine") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "2-acetyloxy-N,N,N-trimethylethanaminium") -AnnotationAssertion(Annotation( "PDBeChem") "ACETYLCHOLINE") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Acetylcholine") -AnnotationAssertion(Annotation( "UniProt") "acetylcholine") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChemIDplus") "ACh") -AnnotationAssertion(Annotation( "ChEBI") "Azetylcholin") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "O-Acetylcholine") -AnnotationAssertion(Annotation( "ChemIDplus") "choline acetate") -AnnotationAssertion( "CHEBI:15355") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "acetylcholine") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (acetic acid) - -AnnotationAssertion( "A simple monocarboxylic acid containing two carbons.") -AnnotationAssertion( "0") -AnnotationAssertion( "C2H4O2") -AnnotationAssertion( "InChI=1S/C2H4O2/c1-2(3)4/h1H3,(H,3,4)") -AnnotationAssertion( "QTBSBXVTEAMEQO-UHFFFAOYSA-N") -AnnotationAssertion( "60.05200") -AnnotationAssertion( "60.02113") -AnnotationAssertion( "CC(O)=O") -AnnotationAssertion( "CHEBI:22169") -AnnotationAssertion( "CHEBI:2387") -AnnotationAssertion( "CHEBI:40486") -AnnotationAssertion(Annotation( "Beilstein") "Beilstein:506007") -AnnotationAssertion(Annotation( "ChemIDplus") "CAS:64-19-7") -AnnotationAssertion(Annotation( "KEGG COMPOUND") "CAS:64-19-7") -AnnotationAssertion(Annotation( "NIST Chemistry WebBook") "CAS:64-19-7") -AnnotationAssertion(Annotation( "DrugCentral") "Drug_Central:4211") -AnnotationAssertion(Annotation( "Gmelin") "Gmelin:1380") -AnnotationAssertion( "HMDB:HMDB0000042") -AnnotationAssertion( "KEGG:C00033") -AnnotationAssertion( "KEGG:D00010") -AnnotationAssertion( "KNApSAcK:C00001176") -AnnotationAssertion(Annotation( "LIPID MAPS") "LIPID_MAPS_instance:LMFA01010002") -AnnotationAssertion( "MetaCyc:ACET") -AnnotationAssertion( "PDBeChem:ACT") -AnnotationAssertion( "PDBeChem:ACY") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:12005138") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:15107950") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:16630552") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:16774200") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:17190852") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:19416101") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:19469536") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:22153255") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:22173419") -AnnotationAssertion( "PPDB:1333") -AnnotationAssertion(Annotation( "Reaxys") "Reaxys:506007") -AnnotationAssertion( "Wikipedia:Acetic_acid") -AnnotationAssertion(Annotation( "PDBeChem") "ACETIC ACID") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Acetic acid") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "acetic acid") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "AcOH") -AnnotationAssertion(Annotation( "IUPAC") "CH3-COOH") -AnnotationAssertion(Annotation( "ChEBI") "CH3CO2H") -AnnotationAssertion(Annotation( "ChEBI") "E 260") -AnnotationAssertion(Annotation( "ChEBI") "E-260") -AnnotationAssertion(Annotation( "ChEBI") "E260") -AnnotationAssertion(Annotation( "ChEBI") "Essigsaeure") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Ethanoic acid") -AnnotationAssertion(Annotation( "ChemIDplus") "Ethylic acid") -AnnotationAssertion(Annotation( "ChEBI") "HOAc") -AnnotationAssertion(Annotation( "ChEBI") "INS No. 260") -AnnotationAssertion(Annotation( "ChEBI") "MeCO2H") -AnnotationAssertion(Annotation( "ChEBI") "MeCOOH") -AnnotationAssertion(Annotation( "ChemIDplus") "Methanecarboxylic acid") -AnnotationAssertion(Annotation( "ChemIDplus") "acide acetique") -AnnotationAssertion(Annotation( "ChEBI") "ethoic acid") -AnnotationAssertion( "CHEBI:15366") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "acetic acid") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (water) - -AnnotationAssertion( "An oxygen hydride consisting of an oxygen atom that is covalently bonded to two hydrogen atoms") -AnnotationAssertion( "0") -AnnotationAssertion( "H2O") -AnnotationAssertion( "InChI=1S/H2O/h1H2") -AnnotationAssertion( "XLYOFNOQVPJJNP-UHFFFAOYSA-N") -AnnotationAssertion( "18.01530") -AnnotationAssertion( "18.01056") -AnnotationAssertion( "[H]O[H]") -AnnotationAssertion( "CHEBI:10743") -AnnotationAssertion( "CHEBI:13352") -AnnotationAssertion( "CHEBI:27313") -AnnotationAssertion( "CHEBI:42043") -AnnotationAssertion( "CHEBI:42857") -AnnotationAssertion( "CHEBI:43228") -AnnotationAssertion( "CHEBI:44292") -AnnotationAssertion( "CHEBI:44701") -AnnotationAssertion( "CHEBI:44819") -AnnotationAssertion( "CHEBI:5585") -AnnotationAssertion(Annotation( "Beilstein") "Beilstein:3587155") -AnnotationAssertion(Annotation( "ChemIDplus") "CAS:7732-18-5") -AnnotationAssertion(Annotation( "KEGG COMPOUND") "CAS:7732-18-5") -AnnotationAssertion(Annotation( "NIST Chemistry WebBook") "CAS:7732-18-5") -AnnotationAssertion(Annotation( "Gmelin") "Gmelin:117") -AnnotationAssertion( "HMDB:HMDB0002111") -AnnotationAssertion( "KEGG:C00001") -AnnotationAssertion( "KEGG:D00001") -AnnotationAssertion( "MetaCyc:WATER") -AnnotationAssertion( "MolBase:1") -AnnotationAssertion( "PDBeChem:HOH") -AnnotationAssertion(Annotation( "Reaxys") "Reaxys:3587155") -AnnotationAssertion( "Wikipedia:Water") -AnnotationAssertion(Annotation( "PDBeChem") "WATER") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Water") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "oxidane") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "water") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "PDBeChem") "BOUND WATER") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "H2O") -AnnotationAssertion(Annotation( "UniProt") "H2O") -AnnotationAssertion(Annotation( "ChEBI") "HOH") -AnnotationAssertion(Annotation( "ChEBI") "Wasser") -AnnotationAssertion(Annotation( "IUPAC") "[OH2]") -AnnotationAssertion(Annotation( "ChEBI") "acqua") -AnnotationAssertion(Annotation( "ChEBI") "agua") -AnnotationAssertion(Annotation( "ChEBI") "aqua") -AnnotationAssertion(Annotation( "IUPAC") "dihydridooxygen") -AnnotationAssertion(Annotation( "IUPAC") "dihydrogen oxide") -AnnotationAssertion(Annotation( "ChEBI") "eau") -AnnotationAssertion(Annotation( "ChEBI") "hydrogen hydroxide") -AnnotationAssertion( "CHEBI:15377") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "water") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (hydron) - -AnnotationAssertion( "The general name for the hydrogen nucleus, to be used without regard to the hydrogen nuclear mass (either for hydrogen in its natural abundance or where it is not desired to distinguish between the isotopes).") -AnnotationAssertion( "+1") -AnnotationAssertion( "H") -AnnotationAssertion( "InChI=1S/p+1") -AnnotationAssertion( "GPRLSGONYQIRFK-UHFFFAOYSA-N") -AnnotationAssertion( "1.00794") -AnnotationAssertion( "1.008") -AnnotationAssertion( "[H+]") -AnnotationAssertion( "CHEBI:10744") -AnnotationAssertion( "CHEBI:13357") -AnnotationAssertion( "CHEBI:5584") -AnnotationAssertion( "KEGG:C00080") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Hydron") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "hydrogen(1+)") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "hydron") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "UniProt") "H(+)") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "H+") -AnnotationAssertion( "CHEBI:15378") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "hydron") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (dioxygen) - -AnnotationAssertion( "0") -AnnotationAssertion( "O2") -AnnotationAssertion( "InChI=1S/O2/c1-2") -AnnotationAssertion( "MYMOFIZGZYHOMD-UHFFFAOYSA-N") -AnnotationAssertion( "31.998") -AnnotationAssertion( "31.98983") -AnnotationAssertion( "O=O") -AnnotationAssertion( "CHEBI:10745") -AnnotationAssertion( "CHEBI:13416") -AnnotationAssertion( "CHEBI:23833") -AnnotationAssertion( "CHEBI:25366") -AnnotationAssertion( "CHEBI:30491") -AnnotationAssertion( "CHEBI:44742") -AnnotationAssertion( "CHEBI:7860") -AnnotationAssertion(Annotation( "ChemIDplus") "CAS:7782-44-7") -AnnotationAssertion(Annotation( "KEGG COMPOUND") "CAS:7782-44-7") -AnnotationAssertion(Annotation( "NIST Chemistry WebBook") "CAS:7782-44-7") -AnnotationAssertion(Annotation( "Gmelin") "Gmelin:485") -AnnotationAssertion( "HMDB:HMDB0001377") -AnnotationAssertion( "KEGG:C00007") -AnnotationAssertion( "KEGG:D00003") -AnnotationAssertion( "MetaCyc:OXYGEN-MOLECULE") -AnnotationAssertion( "MolBase:750") -AnnotationAssertion( "PDBeChem:OXY") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:10906528") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:16977326") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:18210929") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:18638417") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:19840863") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:7710549") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:9463773") -AnnotationAssertion( "Wikipedia:Oxygen") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "dioxygen") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "Disauerstoff") -AnnotationAssertion(Annotation( "ChEBI") "E 948") -AnnotationAssertion(Annotation( "ChEBI") "E-948") -AnnotationAssertion(Annotation( "ChEBI") "E948") -AnnotationAssertion(Annotation( "IUPAC") "O2") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "O2") -AnnotationAssertion(Annotation( "UniProt") "O2") -AnnotationAssertion(Annotation( "PDBeChem") "OXYGEN MOLECULE") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Oxygen") -AnnotationAssertion(Annotation( "MolBase") "[OO]") -AnnotationAssertion(Annotation( "ChEBI") "dioxygene") -AnnotationAssertion(Annotation( "ChEBI") "molecular oxygen") -AnnotationAssertion( "CHEBI:15379") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "dioxygen") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (ATP) - -AnnotationAssertion( "An adenosine 5'-phosphate in which the 5'-phosphate is a triphosphate group. It is involved in the transportation of chemical energy during metabolic pathways.") -AnnotationAssertion( "0") -AnnotationAssertion( "C10H16N5O13P3") -AnnotationAssertion( "InChI=1S/C10H16N5O13P3/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20)/t4-,6-,7-,10-/m1/s1") -AnnotationAssertion( "ZKHQWZAMYRWXGA-KQYNXXCUSA-N") -AnnotationAssertion( "507.18100") -AnnotationAssertion( "506.99575") -AnnotationAssertion( "Nc1ncnc2n(cnc12)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O") -AnnotationAssertion( "CHEBI:10789") -AnnotationAssertion( "CHEBI:10841") -AnnotationAssertion( "CHEBI:13236") -AnnotationAssertion( "CHEBI:22249") -AnnotationAssertion( "CHEBI:2359") -AnnotationAssertion( "CHEBI:40938") -AnnotationAssertion(Annotation( "Beilstein") "Beilstein:73010") -AnnotationAssertion(Annotation( "ChemIDplus") "CAS:56-65-5") -AnnotationAssertion(Annotation( "KEGG COMPOUND") "CAS:56-65-5") -AnnotationAssertion( "DrugBank:DB00171") -AnnotationAssertion(Annotation( "DrugCentral") "Drug_Central:91") -AnnotationAssertion(Annotation( "Gmelin") "Gmelin:34857") -AnnotationAssertion( "HMDB:HMDB0000538") -AnnotationAssertion( "KEGG:C00002") -AnnotationAssertion( "KEGG:D08646") -AnnotationAssertion( "KNApSAcK:C00001491") -AnnotationAssertion( "PDBeChem:ATP") -AnnotationAssertion( "Patent:US3079379") -AnnotationAssertion(Annotation( "Reaxys") "Reaxys:73010") -AnnotationAssertion( "Wikipedia:Adenosine_triphosphate") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "ATP") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "adenosine 5'-(tetrahydrogen triphosphate)") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "PDBeChem") "ADENOSINE-5'-TRIPHOSPHATE") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Adenosine 5'-triphosphate") -AnnotationAssertion(Annotation( "ChemIDplus") "Adenosine triphosphate") -AnnotationAssertion(Annotation( "IUPAC") "H4atp") -AnnotationAssertion( "CHEBI:15422") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "ATP") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (squalene) AnnotationAssertion( "A triterpene consisting of 2,6,10,15,19,23-hexamethyltetracosane having six double bonds at the 2-, 6-, 10-, 14-, 18- and 22-positions with (all-E)-configuration.") @@ -17619,118 +8479,6 @@ SubClassOf( ObjectSomeValuesFrom( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (aldose) - -AnnotationAssertion( "Aldehydic parent sugars (polyhydroxy aldehydes H[CH(OH)]nC(=O)H, n >= 2) and their intramolecular hemiacetals.") -AnnotationAssertion( "0") -AnnotationAssertion( "C2H4O2(CH2O)n") -AnnotationAssertion( "CHEBI:13755") -AnnotationAssertion( "CHEBI:22305") -AnnotationAssertion( "CHEBI:2561") -AnnotationAssertion( "KEGG:C01370") -AnnotationAssertion( "Wikipedia:Aldose") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Aldose") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "aldoses") -AnnotationAssertion(Annotation( "UniProt") "an aldose") -AnnotationAssertion( "CHEBI:15693") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "aldose") -SubClassOf( ) - -# Class: (L-alpha-amino acid) - -AnnotationAssertion( "Any alpha-amino acid having L-configuration at the alpha-carbon.") -AnnotationAssertion( "0") -AnnotationAssertion( "C2H4NO2R") -AnnotationAssertion( "74.05870") -AnnotationAssertion( "74.02420") -AnnotationAssertion( "N[C@@H]([*])C(O)=O") -AnnotationAssertion( "CHEBI:13072") -AnnotationAssertion( "CHEBI:13243") -AnnotationAssertion( "CHEBI:13797") -AnnotationAssertion( "CHEBI:21224") -AnnotationAssertion( "CHEBI:6175") -AnnotationAssertion( "KEGG:C00151") -AnnotationAssertion(Annotation( "IUPAC") "L-alpha-amino acid") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "L-alpha-amino acids") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "L-2-Amino acid") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "L-Amino acid") -AnnotationAssertion(Annotation( "ChEBI") "L-alpha-amino acids") -AnnotationAssertion( "CHEBI:15705") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "L-alpha-amino acid") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (primary alcohol) - -AnnotationAssertion( "A primary alcohol is a compound in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it.") -AnnotationAssertion( "0") -AnnotationAssertion( "CH3OR") -AnnotationAssertion( "31.034") -AnnotationAssertion( "31.01839") -AnnotationAssertion( "*C(O)([H])[H]") -AnnotationAssertion( "CHEBI:13676") -AnnotationAssertion( "CHEBI:14887") -AnnotationAssertion( "CHEBI:26262") -AnnotationAssertion( "CHEBI:57489") -AnnotationAssertion( "CHEBI:8406") -AnnotationAssertion( "KEGG:C00226") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Primary alcohol") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "1-Alcohol") -AnnotationAssertion(Annotation( "UniProt") "a primary alcohol") -AnnotationAssertion(Annotation( "ChEBI") "primary alcohols") -AnnotationAssertion( "CHEBI:15734") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "primary alcohol") -SubClassOf( ) - -# Class: (formate) - -AnnotationAssertion( "A monocarboxylic acid anion that is the conjugate base of formic acid. Induces severe metabolic acidosis and ocular injury in human subjects.") -AnnotationAssertion( "-1") -AnnotationAssertion( "CHO2") -AnnotationAssertion( "InChI=1S/CH2O2/c2-1-3/h1H,(H,2,3)/p-1") -AnnotationAssertion( "BDAGIHXWWSANSR-UHFFFAOYSA-M") -AnnotationAssertion( "45.01744") -AnnotationAssertion( "44.99820") -AnnotationAssertion( "[H]C([O-])=O") -AnnotationAssertion( "CHEBI:14276") -AnnotationAssertion( "CHEBI:24081") -AnnotationAssertion(Annotation( "Beilstein") "Beilstein:1901205") -AnnotationAssertion(Annotation( "ChemIDplus") "CAS:71-47-6") -AnnotationAssertion(Annotation( "NIST Chemistry WebBook") "CAS:71-47-6") -AnnotationAssertion(Annotation( "Gmelin") "Gmelin:1006") -AnnotationAssertion( "HMDB:HMDB0000142") -AnnotationAssertion( "KEGG:C00058") -AnnotationAssertion( "MetaCyc:FORMATE") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:17190852") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:3946945") -AnnotationAssertion(Annotation( "Reaxys") "Reaxys:1901205") -AnnotationAssertion(Annotation( "UM-BBD") "UM-BBD_compID:c0106") -AnnotationAssertion( "Wikipedia:Formate") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "formate") -AnnotationAssertion(Annotation( "UniProt") "formate") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "NIST_Chemistry_WebBook") "HCO2 anion") -AnnotationAssertion(Annotation( "ChEBI") "aminate") -AnnotationAssertion(Annotation( "ChEBI") "formiate") -AnnotationAssertion(Annotation( "ChemIDplus") "formic acid, ion(1-)") -AnnotationAssertion(Annotation( "ChEBI") "formylate") -AnnotationAssertion(Annotation( "ChEBI") "hydrogen carboxylate") -AnnotationAssertion(Annotation( "ChEBI") "methanoate") -AnnotationAssertion( "CHEBI:15740") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "formate") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (polypeptide) AnnotationAssertion( "A peptide containing ten or more amino acid residues.") @@ -17749,139 +8497,6 @@ AnnotationAssertion(rdfs:label "pol SubClassOf( ) SubClassOf( ) -# Class: (D-glutamic acid) - -AnnotationAssertion( "An optically active form of glutamic acid having D-configuration.") -AnnotationAssertion( "0") -AnnotationAssertion( "C5H9NO4") -AnnotationAssertion( "InChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m1/s1") -AnnotationAssertion( "WHUUTDBJXJRKMK-GSVOUGTGSA-N") -AnnotationAssertion( "147.12930") -AnnotationAssertion( "147.05316") -AnnotationAssertion( "N[C@H](CCC(O)=O)C(O)=O") -AnnotationAssertion( "CHEBI:21023") -AnnotationAssertion( "CHEBI:4183") -AnnotationAssertion(Annotation( "Beilstein") "Beilstein:1723800") -AnnotationAssertion(Annotation( "ChemIDplus") "CAS:6893-26-1") -AnnotationAssertion(Annotation( "KEGG COMPOUND") "CAS:6893-26-1") -AnnotationAssertion(Annotation( "NIST Chemistry WebBook") "CAS:6893-26-1") -AnnotationAssertion( "DrugBank:DB02517") -AnnotationAssertion(Annotation( "Gmelin") "Gmelin:201189") -AnnotationAssertion( "HMDB:HMDB0003339") -AnnotationAssertion( "KEGG:C00217") -AnnotationAssertion( "KNApSAcK:C00019577") -AnnotationAssertion( "MetaCyc:D-GLT") -AnnotationAssertion( "PDBeChem:DGL") -AnnotationAssertion(Annotation( "Reaxys") "Reaxys:1723800") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "(2R)-2-aminopentanedioic acid") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "D-Glutamic acid") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "D-glutamic acid") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "(R)-2-aminopentanedioic acid") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "D-2-Aminoglutaric acid") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "D-Glutaminic acid") -AnnotationAssertion(Annotation( "ChEBI") "D-Glutaminsaeure") -AnnotationAssertion(Annotation( "PDBeChem") "DGL") -AnnotationAssertion(Annotation( "ChemIDplus") "glutamic acid D-form") -AnnotationAssertion( "CHEBI:15966") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "D-glutamic acid") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (polynucleotide) - -AnnotationAssertion( "A nucleobase-containing molecular entity with a polymeric structure comprised of a linear sequence of 13 or more nucleotide residues.") -AnnotationAssertion( "0") -AnnotationAssertion( "(C5H8O6PR)n.C10H17O10PR2") -AnnotationAssertion( "CHEBI:13672") -AnnotationAssertion( "CHEBI:14859") -AnnotationAssertion( "CHEBI:8312") -AnnotationAssertion( "KEGG:C00419") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Polynucleotide") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "polynucleotides") -AnnotationAssertion( "CHEBI:15986") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "polynucleotide") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (L-glutamic acid) - -AnnotationAssertion( "An optically active form of glutamic acid having L-configuration.") -AnnotationAssertion( "0") -AnnotationAssertion( "C5H9NO4") -AnnotationAssertion( "InChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m0/s1") -AnnotationAssertion( "WHUUTDBJXJRKMK-VKHMYHEASA-N") -AnnotationAssertion( "147.12930") -AnnotationAssertion( "147.05316") -AnnotationAssertion( "N[C@@H](CCC(O)=O)C(O)=O") -AnnotationAssertion( "CHEBI:21304") -AnnotationAssertion( "CHEBI:42825") -AnnotationAssertion( "CHEBI:6224") -AnnotationAssertion( "BPDB:2297") -AnnotationAssertion(Annotation( "Beilstein") "Beilstein:1723801") -AnnotationAssertion(Annotation( "ChemIDplus") "CAS:56-86-0") -AnnotationAssertion(Annotation( "KEGG COMPOUND") "CAS:56-86-0") -AnnotationAssertion(Annotation( "NIST Chemistry WebBook") "CAS:56-86-0") -AnnotationAssertion( "DrugBank:DB00142") -AnnotationAssertion(Annotation( "DrugCentral") "Drug_Central:1310") -AnnotationAssertion(Annotation( "Gmelin") "Gmelin:3502") -AnnotationAssertion( "HMDB:HMDB0000148") -AnnotationAssertion( "KEGG:C00025") -AnnotationAssertion( "KEGG:D00007") -AnnotationAssertion( "KNApSAcK:C00001358") -AnnotationAssertion( "LINCS:LSM-36375") -AnnotationAssertion( "MetaCyc:GLT") -AnnotationAssertion( "PDBeChem:GLU_LFOH") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:15739367") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:15930465") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:16719819") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:16892196") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:19581495") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:22219301") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:22735334") -AnnotationAssertion(Annotation( "Reaxys") "Reaxys:1723801") -AnnotationAssertion( "Wikipedia:L-Glutamic_Acid") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "(2S)-2-aminopentanedioic acid") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "L-Glutamic acid") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "L-glutamic acid") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "(S)-2-aminopentanedioic acid") -AnnotationAssertion(Annotation( "NIST_Chemistry_WebBook") "(S)-glutamic acid") -AnnotationAssertion(Annotation( "ChEBI") "E") -AnnotationAssertion(Annotation( "PDBeChem") "GLUTAMIC ACID") -AnnotationAssertion(Annotation( "ChEBI") "Glu") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Glutamate") -AnnotationAssertion(Annotation( "ChEBI") "L-Glu") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "L-Glutaminic acid") -AnnotationAssertion(Annotation( "ChEBI") "L-Glutaminsaeure") -AnnotationAssertion(Annotation( "ChEBI") Annotation( ) "acide glutamique") -AnnotationAssertion(Annotation( "ChEBI") Annotation( ) "acido glutamico") -AnnotationAssertion(Annotation( "ChEBI") Annotation( ) "acidum glutamicum") -AnnotationAssertion(Annotation( "ChEBI") Annotation( ) "glutamic acid") -AnnotationAssertion( "CHEBI:16015") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "L-glutamic acid") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (ammonia) AnnotationAssertion( "An azane that consists of a single nitrogen atom covelently bonded to three hydrogen atoms.") @@ -18083,40 +8698,6 @@ SubClassOf( ObjectSomeValuesFrom( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (hydroxide) - -AnnotationAssertion( "-1") -AnnotationAssertion( "HO") -AnnotationAssertion( "InChI=1S/H2O/h1H2/p-1") -AnnotationAssertion( "XLYOFNOQVPJJNP-UHFFFAOYSA-M") -AnnotationAssertion( "17.00734") -AnnotationAssertion( "17.00329") -AnnotationAssertion( "[O-][H]") -AnnotationAssertion( "CHEBI:13365") -AnnotationAssertion( "CHEBI:13419") -AnnotationAssertion( "CHEBI:44641") -AnnotationAssertion( "CHEBI:5594") -AnnotationAssertion(Annotation( "ChemIDplus") "CAS:14280-30-9") -AnnotationAssertion(Annotation( "NIST Chemistry WebBook") "CAS:14280-30-9") -AnnotationAssertion(Annotation( "Gmelin") "Gmelin:24714") -AnnotationAssertion( "KEGG:C01328") -AnnotationAssertion( "PDBeChem:OH") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "hydridooxygenate(1-)") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "hydroxide") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "oxidanide") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "HO-") -AnnotationAssertion(Annotation( "PDBeChem") "HYDROXIDE ION") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Hydroxide ion") -AnnotationAssertion(Annotation( "IUPAC") "OH(-)") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "OH-") -AnnotationAssertion( "CHEBI:16234") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "hydroxide") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (phospholipid) AnnotationAssertion( "A lipid containing phosphoric acid as a mono- or di-ester. The term encompasses phosphatidic acids and phosphoglycerides.") @@ -18136,81 +8717,6 @@ SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (adenosine) - -AnnotationAssertion( "A ribonucleoside composed of a molecule of adenine attached to a ribofuranose moiety via a beta-N(9)-glycosidic bond.") -AnnotationAssertion( "0") -AnnotationAssertion( "C10H13N5O4") -AnnotationAssertion( "InChI=1S/C10H13N5O4/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(18)6(17)4(1-16)19-10/h2-4,6-7,10,16-18H,1H2,(H2,11,12,13)/t4-,6-,7-,10-/m1/s1") -AnnotationAssertion( "OIRDTQYFTABQOQ-KQYNXXCUSA-N") -AnnotationAssertion( "267.24152") -AnnotationAssertion( "267.09675") -AnnotationAssertion( "Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O") -AnnotationAssertion( "CHEBI:13734") -AnnotationAssertion( "CHEBI:22237") -AnnotationAssertion( "CHEBI:2472") -AnnotationAssertion( "CHEBI:40558") -AnnotationAssertion( "CHEBI:40825") -AnnotationAssertion( "CHEBI:40906") -AnnotationAssertion(Annotation( "Beilstein") "Beilstein:93029") -AnnotationAssertion(Annotation( "ChemIDplus") "CAS:58-61-7") -AnnotationAssertion(Annotation( "KEGG COMPOUND") "CAS:58-61-7") -AnnotationAssertion(Annotation( "NIST Chemistry WebBook") "CAS:58-61-7") -AnnotationAssertion( "DrugBank:DB00640") -AnnotationAssertion(Annotation( "DrugCentral") "Drug_Central:90") -AnnotationAssertion( "ECMDB:ECMDB00050") -AnnotationAssertion(Annotation( "Gmelin") "Gmelin:53385") -AnnotationAssertion( "HMDB:HMDB0000050") -AnnotationAssertion( "KEGG:C00212") -AnnotationAssertion( "KEGG:D00045") -AnnotationAssertion( "KNApSAcK:C00007444") -AnnotationAssertion( "LINCS:LSM-28568") -AnnotationAssertion( "MetaCyc:ADENOSINE") -AnnotationAssertion( "PDBeChem:ADN") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:11213237") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:11820865") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:11978011") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:16183671") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:16917093") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:17190852") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:18000974") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:323854") -AnnotationAssertion(Annotation( "Reaxys") "Reaxys:93029") -AnnotationAssertion( "Wikipedia:Adenosine") -AnnotationAssertion( "YMDB:YMDB00058") -AnnotationAssertion(Annotation( "PDBeChem") "ADENOSINE") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Adenosine") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "adenosine") -AnnotationAssertion(Annotation( "UniProt") "adenosine") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "DrugBank") "(2R,3R,4S,5R)-2-(6-aminopurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol") -AnnotationAssertion(Annotation( "ChemIDplus") "6-Amino-9-beta-D-ribofuranosyl-9H-purine") -AnnotationAssertion(Annotation( "ChemIDplus") "9-beta-D-Ribofuranosidoadenine") -AnnotationAssertion(Annotation( "ChemIDplus") "9-beta-D-Ribofuranosyl-9H-purin-6-amine") -AnnotationAssertion(Annotation( "ChEBI") "9-beta-D-ribofuranosyl-9H-purin-6-amine") -AnnotationAssertion(Annotation( "CBN") "Ade-Rib") -AnnotationAssertion(Annotation( "DrugBank") "Adenine Deoxyribonucleoside") -AnnotationAssertion(Annotation( "DrugBank") Annotation( ) "Adenocard") -AnnotationAssertion(Annotation( "DrugBank") Annotation( ) "Adenocor") -AnnotationAssertion(Annotation( "DrugBank") Annotation( ) "Adenoscan") -AnnotationAssertion(Annotation( "ChEBI") "Adenosin") -AnnotationAssertion(Annotation( "DrugBank") "Adenyldeoxyriboside") -AnnotationAssertion(Annotation( "CBN") "Ado") -AnnotationAssertion(Annotation( "DrugBank") "Deoxyadenosine") -AnnotationAssertion(Annotation( "DrugBank") "Desoxyadenosine") -AnnotationAssertion(Annotation( "ChemIDplus") "beta-D-Adenosine") -AnnotationAssertion( "CHEBI:16335") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "adenosine") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (hyaluronic acid) AnnotationAssertion( "A mucopolysaccharide composed of N-acetylglucosamine and glucuronic acid subunits. It is found in the connective tissues of vertebrates. A principal constituent of the extracellular matrix (ECM), it mediates the growth and metastasis of tumour cells.") @@ -18405,102 +8911,6 @@ SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (noradrenaline(1+)) - -AnnotationAssertion( "+1") -AnnotationAssertion( "C8H12NO3") -AnnotationAssertion( "InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2/p+1") -AnnotationAssertion( "SFLSHLFXELFNJZ-UHFFFAOYSA-O") -AnnotationAssertion( "170.187") -AnnotationAssertion( "170.08117") -AnnotationAssertion( "C1=CC(=CC(=C1O)O)C(C[NH3+])O") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "UniProt") "noradrenaline") -AnnotationAssertion( "CHEBI:166902") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "noradrenaline(1+)") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (nucleoside 5'-phosphate) - -AnnotationAssertion( "A ribosyl or deoxyribosyl derivative of a pyrimidine or purine base in which C-5 of the ribose ring is mono-, di-, tri- or tetra-phosphorylated.") -AnnotationAssertion( "0") -AnnotationAssertion( "C5H9O6PR2") -AnnotationAssertion( "196.09510") -AnnotationAssertion( "196.01367") -AnnotationAssertion( "O[C@H]1[C@@H]([*])[C@H]([*])O[C@@H]1COP(O)(O)=O") -AnnotationAssertion( "CHEBI:14674") -AnnotationAssertion( "CHEBI:25603") -AnnotationAssertion( "CHEBI:7650") -AnnotationAssertion( "KEGG:C01117") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Nucleoside 5'-phosphate") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "nucleoside 5'-phosphates") -AnnotationAssertion( "CHEBI:16701") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "nucleoside 5'-phosphate") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (adenine) - -AnnotationAssertion( "The parent compound of the 6-aminopurines, composed of a purine having an amino group at C-6.") -AnnotationAssertion( "0") -AnnotationAssertion( "C5H5N5") -AnnotationAssertion( "InChI=1S/C5H5N5/c6-4-3-5(9-1-7-3)10-2-8-4/h1-2H,(H3,6,7,8,9,10)") -AnnotationAssertion( "GFFGJBXGBJISGV-UHFFFAOYSA-N") -AnnotationAssertion( "135.12690") -AnnotationAssertion( "135.05450") -AnnotationAssertion( "Nc1ncnc2[nH]cnc12") -AnnotationAssertion( "CHEBI:13733") -AnnotationAssertion( "CHEBI:22236") -AnnotationAssertion( "CHEBI:2470") -AnnotationAssertion( "CHEBI:40579") -AnnotationAssertion(Annotation( "Beilstein") "Beilstein:608603") -AnnotationAssertion(Annotation( "ChemIDplus") "CAS:73-24-5") -AnnotationAssertion(Annotation( "KEGG COMPOUND") "CAS:73-24-5") -AnnotationAssertion(Annotation( "NIST Chemistry WebBook") "CAS:73-24-5") -AnnotationAssertion( "DrugBank:DB00173") -AnnotationAssertion(Annotation( "DrugCentral") "Drug_Central:89") -AnnotationAssertion(Annotation( "Gmelin") "Gmelin:3903") -AnnotationAssertion( "HMDB:HMDB0000034") -AnnotationAssertion( "KEGG:C00147") -AnnotationAssertion( "KEGG:D00034") -AnnotationAssertion( "KNApSAcK:C00001490") -AnnotationAssertion( "MetaCyc:ADENINE") -AnnotationAssertion( "PDBeChem:ADE") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:11985597") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:12829005") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:12951489") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:15063338") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:15715490") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:17439666") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:8070089") -AnnotationAssertion(Annotation( "Reaxys") "Reaxys:608603") -AnnotationAssertion( "Wikipedia:Adenine") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "9H-purin-6-amine") -AnnotationAssertion(Annotation( "PDBeChem") "ADENINE") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Adenine") -AnnotationAssertion(Annotation( "UniProt") "adenine") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "6-Aminopurine") -AnnotationAssertion(Annotation( "ChEBI") "A") -AnnotationAssertion(Annotation( "CBN") "Ade") -AnnotationAssertion(Annotation( "NIST_Chemistry_WebBook") "Adenin") -AnnotationAssertion( "CHEBI:16708") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "adenine") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (mineral nutrient) AnnotationAssertion( "A mineral that is an inorganic nutrient which must be ingested and absorbed in adequate amounts to satisfy a wide range of essential metabolic and/or structural functions in the human body.") @@ -18516,30 +8926,6 @@ AnnotationAssertion(rdfs:label "mi SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (D-alpha-amino acid) - -AnnotationAssertion( "0") -AnnotationAssertion( "C2H4NO2R") -AnnotationAssertion( "74.05870") -AnnotationAssertion( "74.02420") -AnnotationAssertion( "N[C@H]([*])C(O)=O") -AnnotationAssertion( "CHEBI:12909") -AnnotationAssertion( "CHEBI:13625") -AnnotationAssertion( "CHEBI:20906") -AnnotationAssertion( "CHEBI:4097") -AnnotationAssertion( "KEGG:C00405") -AnnotationAssertion(Annotation( "ChEBI") "D-alpha-amino acid") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "D-alpha-amino acids") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "D-Amino acid") -AnnotationAssertion(Annotation( "ChEBI") "D-alpha-amino acids") -AnnotationAssertion( "CHEBI:16733") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "D-alpha-amino acid") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (glycan) AnnotationAssertion( "Any oligosaccharide, polysaccharide or their derivatives consisting of monosaccharides or monosaccharide derivatives linked by glycosidic bonds. See also http://www.ontobee.org/ontology/GNO?iri=http://purl.obolibrary.org/obo/GNO_00000001.") @@ -18550,270 +8936,6 @@ AnnotationAssertion( "glycan") SubClassOf( ) -# Class: (ADP) - -AnnotationAssertion( "A purine ribonucleoside 5'-diphosphate having adenine as the nucleobase.") -AnnotationAssertion( "0") -AnnotationAssertion( "C10H15N5O10P2") -AnnotationAssertion( "InChI=1S/C10H15N5O10P2/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(24-10)1-23-27(21,22)25-26(18,19)20/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H2,11,12,13)(H2,18,19,20)/t4-,6-,7-,10-/m1/s1") -AnnotationAssertion( "XTWYTFMLZFPYCI-KQYNXXCUSA-N") -AnnotationAssertion( "427.20110") -AnnotationAssertion( "427.02942") -AnnotationAssertion( "Nc1ncnc2n(cnc12)[C@@H]1O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O") -AnnotationAssertion( "CHEBI:13222") -AnnotationAssertion( "CHEBI:22244") -AnnotationAssertion( "CHEBI:2342") -AnnotationAssertion( "CHEBI:40553") -AnnotationAssertion(Annotation( "Beilstein") "Beilstein:67722") -AnnotationAssertion(Annotation( "KEGG COMPOUND") "CAS:20398-34-9") -AnnotationAssertion(Annotation( "ChemIDplus") "CAS:58-64-0") -AnnotationAssertion(Annotation( "KEGG COMPOUND") "CAS:58-64-0") -AnnotationAssertion( "COMe:MOL000173") -AnnotationAssertion( "DrugBank:DB03431") -AnnotationAssertion(Annotation( "Gmelin") "Gmelin:88452") -AnnotationAssertion( "KEGG:C00008") -AnnotationAssertion( "KEGG:G11113") -AnnotationAssertion( "KNApSAcK:C00019353") -AnnotationAssertion( "PDBeChem:ADP") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:16295522") -AnnotationAssertion(Annotation( "Reaxys") "Reaxys:67722") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "ADP") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "adenosine 5'-(trihydrogen diphosphate)") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChemIDplus") "5'-adenylphosphoric acid") -AnnotationAssertion(Annotation( "PDBeChem") "ADENOSINE-5'-DIPHOSPHATE") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Adenosine 5'-diphosphate") -AnnotationAssertion(Annotation( "IUPAC") "H3adp") -AnnotationAssertion( "CHEBI:16761") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "ADP") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (tryptamine) - -AnnotationAssertion( "An aminoalkylindole consisting of indole having a 2-aminoethyl group at the 3-position.") -AnnotationAssertion( "0") -AnnotationAssertion( "C10H12N2") -AnnotationAssertion( "InChI=1S/C10H12N2/c11-6-5-8-7-12-10-4-2-1-3-9(8)10/h1-4,7,12H,5-6,11H2") -AnnotationAssertion( "APJYDQYYACXCRM-UHFFFAOYSA-N") -AnnotationAssertion( "160.21570") -AnnotationAssertion( "160.10005") -AnnotationAssertion( "NCCc1c[nH]c2ccccc12") -AnnotationAssertion( "CHEBI:15274") -AnnotationAssertion( "CHEBI:27161") -AnnotationAssertion( "CHEBI:46157") -AnnotationAssertion( "CHEBI:9767") -AnnotationAssertion(Annotation( "Beilstein") "Beilstein:125513") -AnnotationAssertion(Annotation( "ChemIDplus") "CAS:61-54-1") -AnnotationAssertion(Annotation( "KEGG COMPOUND") "CAS:61-54-1") -AnnotationAssertion(Annotation( "NIST Chemistry WebBook") "CAS:61-54-1") -AnnotationAssertion( "DrugBank:DB08653") -AnnotationAssertion(Annotation( "Gmelin") "Gmelin:603448") -AnnotationAssertion( "HMDB:HMDB0000303") -AnnotationAssertion( "KEGG:C00398") -AnnotationAssertion( "KNApSAcK:C00001434") -AnnotationAssertion( "MetaCyc:TRYPTAMINE") -AnnotationAssertion( "PDBeChem:TSS") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:16126914") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:22770225") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:24345948") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:24558969") -AnnotationAssertion(Annotation( "Reaxys") "Reaxys:125513") -AnnotationAssertion( "Wikipedia:Tryptamine") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "2-(1H-indol-3-yl)ethanamine") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Tryptamine") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "NIST_Chemistry_WebBook") "1H-indole-3-ethanamine") -AnnotationAssertion(Annotation( "PDBeChem") "2-(1H-INDOL-3-YL)ETHANAMINE") -AnnotationAssertion(Annotation( "ChemIDplus") "2-(3-indolyl)ethylamine") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "3-(2-Aminoethyl)indole") -AnnotationAssertion( "CHEBI:16765") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "tryptamine") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (melatonin) - -AnnotationAssertion( "A member of the class of acetamides that is acetamide in which one of the hydrogens attached to the nitrogen atom is replaced by a 2-(5-methoxy-1H-indol-3-yl)ethyl group. It is a hormone secreted by the pineal gland in humans.") -AnnotationAssertion( "0") -AnnotationAssertion( "C13H16N2O2") -AnnotationAssertion( "InChI=1S/C13H16N2O2/c1-9(16)14-6-5-10-8-15-13-4-3-11(17-2)7-12(10)13/h3-4,7-8,15H,5-6H2,1-2H3,(H,14,16)") -AnnotationAssertion( "DRLFMBDRBRZALE-UHFFFAOYSA-N") -AnnotationAssertion( "232.283") -AnnotationAssertion( "232.12118") -AnnotationAssertion( "C=1C=C(C=C2C(=CNC12)CCNC(=O)C)OC") -AnnotationAssertion( "CHEBI:14577") -AnnotationAssertion( "CHEBI:25180") -AnnotationAssertion( "CHEBI:6730") -AnnotationAssertion(Annotation( "Beilstein") "Beilstein:205542") -AnnotationAssertion(Annotation( "ChemIDplus") "CAS:73-31-4") -AnnotationAssertion(Annotation( "KEGG COMPOUND") "CAS:73-31-4") -AnnotationAssertion(Annotation( "NIST Chemistry WebBook") "CAS:73-31-4") -AnnotationAssertion( "DrugBank:DB01065") -AnnotationAssertion(Annotation( "DrugCentral") "Drug_Central:1672") -AnnotationAssertion( "HMDB:HMDB0001389") -AnnotationAssertion( "KEGG:C01598") -AnnotationAssertion( "KEGG:D08170") -AnnotationAssertion( "LINCS:LSM-4779") -AnnotationAssertion( "MetaCyc:N-ACETYL-5-METHOXY-TRYPTAMINE") -AnnotationAssertion( "PDBeChem:ML1") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:16678784") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:18212404") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:18485664") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:8290600") -AnnotationAssertion(Annotation( "Reaxys") "Reaxys:205542") -AnnotationAssertion( "Wikipedia:Melatonin") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Melatonin") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "N-[2-(5-methoxy-1H-indol-3-yl)ethyl]acetamide") -AnnotationAssertion(Annotation( "UniProt") "melatonin") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChemIDplus") "5-methoxy-N-acetyltryptamine") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "N-Acetyl-5-methoxytryptamine") -AnnotationAssertion(Annotation( "NIST_Chemistry_WebBook") "N-[2-(5-methoxyindol-3-yl)ethyl]acetamide") -AnnotationAssertion(Annotation( "ChEBI") "melatonine") -AnnotationAssertion( "CHEBI:16796") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "melatonin") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (nucleoside 5'-diphosphate) - -AnnotationAssertion( "0") -AnnotationAssertion( "C5H11O10P2R") -AnnotationAssertion( "293.08240") -AnnotationAssertion( "292.98274") -AnnotationAssertion( "O[C@H]1[C@H]([*])O[C@H](COP(O)(=O)OP(O)(O)=O)[C@H]1O") -AnnotationAssertion( "CHEBI:13401") -AnnotationAssertion( "CHEBI:13662") -AnnotationAssertion( "CHEBI:14675") -AnnotationAssertion( "CHEBI:25606") -AnnotationAssertion( "CHEBI:7428") -AnnotationAssertion( "CHEBI:7652") -AnnotationAssertion( "KEGG:C00454") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "NDP") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Nucleoside diphosphate") -AnnotationAssertion(Annotation( "ChEBI") "nucleoside diphosphates") -AnnotationAssertion( "CHEBI:16862") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "nucleoside 5'-diphosphate") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (gamma-aminobutyric acid) - -AnnotationAssertion( "A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.") -AnnotationAssertion( "0") -AnnotationAssertion( "C4H9NO2") -AnnotationAssertion( "InChI=1S/C4H9NO2/c5-3-1-2-4(6)7/h1-3,5H2,(H,6,7)") -AnnotationAssertion( "BTCSSZJGUNDROE-UHFFFAOYSA-N") -AnnotationAssertion( "103.11980") -AnnotationAssertion( "103.06333") -AnnotationAssertion( "NCCCC(O)=O") -AnnotationAssertion( "CHEBI:1786") -AnnotationAssertion( "CHEBI:193777") -AnnotationAssertion( "CHEBI:20318") -AnnotationAssertion( "CHEBI:40483") -AnnotationAssertion( "BPDB:2298") -AnnotationAssertion(Annotation( "Beilstein") "Beilstein:906818") -AnnotationAssertion(Annotation( "ChemIDplus") "CAS:56-12-2") -AnnotationAssertion(Annotation( "KEGG COMPOUND") "CAS:56-12-2") -AnnotationAssertion(Annotation( "NIST Chemistry WebBook") "CAS:56-12-2") -AnnotationAssertion( "DrugBank:DB02530") -AnnotationAssertion(Annotation( "DrugCentral") "Drug_Central:1262") -AnnotationAssertion(Annotation( "Gmelin") "Gmelin:49775") -AnnotationAssertion( "HMDB:HMDB0000112") -AnnotationAssertion( "KEGG:C00334") -AnnotationAssertion( "KEGG:D00058") -AnnotationAssertion( "KNApSAcK:C00001337") -AnnotationAssertion(Annotation( "LIPID MAPS") "LIPID_MAPS_instance:LMFA01100039") -AnnotationAssertion( "MetaCyc:4-AMINO-BUTYRATE") -AnnotationAssertion( "PDBeChem:ABU") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:10630630") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:10930630") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:16276116") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:21614609") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:22770225") -AnnotationAssertion(Annotation( "Reaxys") "Reaxys:906818") -AnnotationAssertion( "Wikipedia:Gamma-Aminobutyric_acid") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "4-aminobutanoic acid") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "gamma-Aminobutyric acid") -AnnotationAssertion(Annotation( "NIST_Chemistry_WebBook") "gamma-aminobutyric acid") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "4-Aminobutanoic acid") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "4-Aminobutyric acid") -AnnotationAssertion(Annotation( "ChEBI") "4-aminobutanoic acid") -AnnotationAssertion(Annotation( "ChEBI") "4-aminobutyric acid") -AnnotationAssertion(Annotation( "ChEBI") "4Abu") -AnnotationAssertion(Annotation( "IUPHAR") "GABA") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "GABA") -AnnotationAssertion(Annotation( "PDBeChem") "GAMMA-AMINO-BUTANOIC ACID") -AnnotationAssertion(Annotation( "NIST_Chemistry_WebBook") "gamma-Aminobuttersaeure") -AnnotationAssertion(Annotation( "NIST_Chemistry_WebBook") "gamma-amino-n-butyric acid") -AnnotationAssertion(Annotation( "NIST_Chemistry_WebBook") "gamma-aminobutanoic acid") -AnnotationAssertion(Annotation( "NIST_Chemistry_WebBook") "omega-aminobutyric acid") -AnnotationAssertion(Annotation( "ChemIDplus") "piperidic acid") -AnnotationAssertion(Annotation( "ChemIDplus") "piperidinic acid") -AnnotationAssertion( "CHEBI:16865") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "gamma-aminobutyric acid") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (D-ribose) - -AnnotationAssertion( "A ribose in which the chiral carbon atom furthest away from the aldehyde group (C4') has the same configuration as in D-glyceraldehyde.") -AnnotationAssertion( "0") -AnnotationAssertion( "C5H10O5") -AnnotationAssertion( "150.12990") -AnnotationAssertion( "150.05282") -AnnotationAssertion( "CHEBI:13011") -AnnotationAssertion( "CHEBI:21078") -AnnotationAssertion( "DrugBank:DB01936") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:24404872") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:24752650") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "D-ribo-pentose") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "D-ribose") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "JCBN") "D-Rib") -AnnotationAssertion( "CHEBI:16988") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "D-ribose") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (bilirubin IXalpha) AnnotationAssertion( "A member of the class of biladienes that is a linear tetrapyrrole with the dipyrrole units being of both exovinyl and endovinyl type. A product of heme degradation, it is produced in the reticuloendothelial system by the reduction of biliverdin and transported to the liver as a complex with serum albumin.") @@ -18866,104 +8988,6 @@ SubClassOf( ObjectSomeValuesFrom( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (deoxyribonucleic acid) - -AnnotationAssertion( "High molecular weight, linear polymers, composed of nucleotides containing deoxyribose and linked by phosphodiester bonds; DNA contain the genetic information of organisms.") -AnnotationAssertion( "CHEBI:13302") -AnnotationAssertion( "CHEBI:21123") -AnnotationAssertion( "CHEBI:33698") -AnnotationAssertion( "CHEBI:4291") -AnnotationAssertion(Annotation( "ChemIDplus") "CAS:9007-49-2") -AnnotationAssertion(Annotation( "KEGG COMPOUND") "CAS:9007-49-2") -AnnotationAssertion( "KEGG:C00039") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Deoxyribonucleic acid") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "deoxyribonucleic acids") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "(Deoxyribonucleotide)m") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "(Deoxyribonucleotide)n") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "(Deoxyribonucleotide)n+m") -AnnotationAssertion(Annotation( "IUPAC") "DNA") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "DNA") -AnnotationAssertion(Annotation( "UniProt") "DNA") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "DNAn") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "DNAn+1") -AnnotationAssertion(Annotation( "ChEBI") "DNS") -AnnotationAssertion(Annotation( "ChEBI") "Desoxyribonukleinsaeure") -AnnotationAssertion(Annotation( "ChEBI") "deoxyribonucleic acids") -AnnotationAssertion(Annotation( "ChemIDplus") "desoxyribose nucleic acid") -AnnotationAssertion(Annotation( "ChEBI") "thymus nucleic acid") -AnnotationAssertion( "CHEBI:16991") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "deoxyribonucleic acid") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (progesterone) - -AnnotationAssertion( "A C21-steroid hormone in which a pregnane skeleton carries oxo substituents at positions 3 and 20 and is unsaturated at C(4)-C(5). As a hormone, it is involved in the female menstrual cycle, pregnancy and embryogenesis of humans and other species.") -AnnotationAssertion( "0") -AnnotationAssertion( "C21H30O2") -AnnotationAssertion( "InChI=1S/C21H30O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h12,16-19H,4-11H2,1-3H3/t16-,17+,18-,19-,20-,21+/m0/s1") -AnnotationAssertion( "RJKFOVLPORLFTN-LEKSSAKUSA-N") -AnnotationAssertion( "314.46170") -AnnotationAssertion( "314.22458") -AnnotationAssertion( "[H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@]1(C)[C@H](CC[C@@]21[H])C(C)=O") -AnnotationAssertion( "CHEBI:14896") -AnnotationAssertion( "CHEBI:18798") -AnnotationAssertion( "CHEBI:26269") -AnnotationAssertion( "CHEBI:439") -AnnotationAssertion( "CHEBI:45786") -AnnotationAssertion( "CHEBI:8453") -AnnotationAssertion(Annotation( "Beilstein") "Beilstein:1915950") -AnnotationAssertion(Annotation( "ChemIDplus") "CAS:57-83-0") -AnnotationAssertion(Annotation( "KEGG COMPOUND") "CAS:57-83-0") -AnnotationAssertion(Annotation( "NIST Chemistry WebBook") "CAS:57-83-0") -AnnotationAssertion( "DrugBank:DB00396") -AnnotationAssertion(Annotation( "DrugCentral") "Drug_Central:2279") -AnnotationAssertion(Annotation( "Gmelin") "Gmelin:708590") -AnnotationAssertion( "HMDB:HMDB0001830") -AnnotationAssertion( "KEGG:C00410") -AnnotationAssertion( "KEGG:D00066") -AnnotationAssertion( "MetaCyc:PROGESTERONE") -AnnotationAssertion( "PDBeChem:STR") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:10438974") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:9506942") -AnnotationAssertion(Annotation( "Reaxys") "Reaxys:1915950") -AnnotationAssertion( "Wikipedia:Progesterone") -AnnotationAssertion(Annotation( "PDBeChem") "PROGESTERONE") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Progesterone") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "pregn-4-ene-3,20-dione") -AnnotationAssertion(Annotation( "UniProt") "progesterone") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "(S)-4-Pregnene-3,20-dione") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "(S)-Pregn-4-en-3,20-dione") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "(S)-Progesterone") -AnnotationAssertion(Annotation( "NIST_Chemistry_WebBook") "17alpha-progesterone") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "4-Pregnene-3,20-dione") -AnnotationAssertion(Annotation( "NIST_Chemistry_WebBook") "Agolutin") -AnnotationAssertion(Annotation( "ChEBI") "Akrolutin") -AnnotationAssertion(Annotation( "ChemIDplus") "Crinone") -AnnotationAssertion(Annotation( "ChEBI") "Delta(4)-pregnene-3,20-dione") -AnnotationAssertion(Annotation( "ChEBI") "Gelbkoerperhormon") -AnnotationAssertion(Annotation( "ChEBI") "Progesteron") -AnnotationAssertion(Annotation( "ChemIDplus") "corpus luteum hormone") -AnnotationAssertion(Annotation( "ChemIDplus") "luteohormone") -AnnotationAssertion( "CHEBI:17026") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "progesterone") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (chitin) AnnotationAssertion( "An aminoglycan consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues.") @@ -18993,34 +9017,6 @@ SubClassOf( ObjectSomeValuesFrom( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (ketone) - -AnnotationAssertion( "A compound in which a carbonyl group is bonded to two carbon atoms: R2C=O (neither R may be H).") -AnnotationAssertion( "0") -AnnotationAssertion( "COR2") -AnnotationAssertion( "28.010") -AnnotationAssertion( "27.99491") -AnnotationAssertion( "[*]C([*])=O") -AnnotationAssertion( "CHEBI:13427") -AnnotationAssertion( "CHEBI:13646") -AnnotationAssertion( "CHEBI:24974") -AnnotationAssertion( "CHEBI:6127") -AnnotationAssertion( "CHEBI:8742") -AnnotationAssertion( "KEGG:C01450") -AnnotationAssertion( "Wikipedia:Ketone") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Ketone") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "ketones") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "Keton") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "R-CO-R'") -AnnotationAssertion(Annotation( "UniProt") "a ketone") -AnnotationAssertion(Annotation( "ChEBI") "cetone") -AnnotationAssertion(Annotation( "ChEBI") "ketones") -AnnotationAssertion( "CHEBI:17087") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "ketone") -SubClassOf( ) - # Class: (glycoprotein) AnnotationAssertion( "A compound in which a carbohydrate component is covalently bound to a protein component.") @@ -19044,62 +9040,6 @@ AnnotationAssertion(rdfs:label "gly SubClassOf( ) SubClassOf( ) -# Class: (glucose) - -AnnotationAssertion( "An aldohexose used as a source of energy and metabolic intermediate.") -AnnotationAssertion( "0") -AnnotationAssertion( "C6H12O6") -AnnotationAssertion( "180.15588") -AnnotationAssertion( "180.06339") -AnnotationAssertion( "CHEBI:14313") -AnnotationAssertion( "CHEBI:24277") -AnnotationAssertion( "CHEBI:33929") -AnnotationAssertion( "CHEBI:5418") -AnnotationAssertion(Annotation( "KEGG COMPOUND") "CAS:50-99-7") -AnnotationAssertion( "KEGG:C00293") -AnnotationAssertion( "Wikipedia:Glucose") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Glucose") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "gluco-hexose") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "glucose") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "DL-glucose") -AnnotationAssertion(Annotation( "JCBN") "Glc") -AnnotationAssertion(Annotation( "ChEBI") "Glukose") -AnnotationAssertion( "CHEBI:17234") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "glucose") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (7H-purine) - -AnnotationAssertion( "The 7H-tautomer of purine.") -AnnotationAssertion( "0") -AnnotationAssertion( "C5H4N4") -AnnotationAssertion( "InChI=1S/C5H4N4/c1-4-5(8-2-6-1)9-3-7-4/h1-3H,(H,6,7,8,9)") -AnnotationAssertion( "KDCGOANMDULRCW-UHFFFAOYSA-N") -AnnotationAssertion( "120.11222") -AnnotationAssertion( "120.04360") -AnnotationAssertion( "c1ncc2[nH]cnc2n1") -AnnotationAssertion( "CHEBI:14968") -AnnotationAssertion( "CHEBI:8639") -AnnotationAssertion(Annotation( "Beilstein") "Beilstein:3200") -AnnotationAssertion(Annotation( "Gmelin") "Gmelin:601779") -AnnotationAssertion( "HMDB:HMDB0001366") -AnnotationAssertion( "KEGG:C15587") -AnnotationAssertion(Annotation( "Reaxys") "Reaxys:3200") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "7H-purine") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Purine") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Purine base") -AnnotationAssertion( "CHEBI:17258") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "7H-purine") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (ferroptosis inhibitor) AnnotationAssertion( "Any substance that inhibits the process of ferroptosis (a type of programmed cell death dependent on iron and characterized by the accumulation of lipid peroxides) in organisms.") @@ -19116,139 +9056,6 @@ AnnotationAssertion(rdfs:label "fe SubClassOf( ) SubClassOf( ) -# Class: (ferroptosis inducer) - -AnnotationAssertion( "Any substance that induces or promotes ferroptosis (a type of programmed cell death dependent on iron and characterized by the accumulation of lipid peroxides) in organisms.") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:31899616") -AnnotationAssertion(Annotation( "SUBMITTER") "PMID:32015325") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:33167414") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:34012798") -AnnotationAssertion( "Wikipedia:Ferroptosis") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "ferroptosis inducers") -AnnotationAssertion( "CHEBI:173085") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "ferroptosis inducer") -SubClassOf( ) - -# Class: (nucleoside 5'-triphoshate) - -AnnotationAssertion( "0") -AnnotationAssertion( "C5H12O13P3R") -AnnotationAssertion( "373.063") -AnnotationAssertion( "372.94908") -AnnotationAssertion( "[C@H]1([C@H]([C@@H](O)[C@@H](O1)*)O)COP(OP(OP(=O)(O)O)(=O)O)(=O)O") -AnnotationAssertion( "CHEBI:13411") -AnnotationAssertion( "CHEBI:14677") -AnnotationAssertion( "CHEBI:25610") -AnnotationAssertion( "CHEBI:7442") -AnnotationAssertion( "CHEBI:7655") -AnnotationAssertion( "KEGG:C00201") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "NTP") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Nucleoside triphosphate") -AnnotationAssertion(Annotation( "ChEBI") "nucleoside triphosphates") -AnnotationAssertion( "CHEBI:17326") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "nucleoside 5'-triphoshate") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (testosterone) - -AnnotationAssertion( "An androstanoid having 17beta-hydroxy and 3-oxo groups, together with unsaturation at C-4-C-5..") -AnnotationAssertion( "0") -AnnotationAssertion( "C19H28O2") -AnnotationAssertion( "InChI=1S/C19H28O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h11,14-17,21H,3-10H2,1-2H3/t14-,15-,16-,17-,18-,19-/m0/s1") -AnnotationAssertion( "MUMGGOZAMZWBJJ-DYKIIFRCSA-N") -AnnotationAssertion( "288.42440") -AnnotationAssertion( "288.20893") -AnnotationAssertion( "[H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@]1(C)[C@@H](O)CC[C@@]21[H]") -AnnotationAssertion( "CHEBI:15214") -AnnotationAssertion( "CHEBI:26883") -AnnotationAssertion( "CHEBI:45798") -AnnotationAssertion( "CHEBI:9461") -AnnotationAssertion(Annotation( "Beilstein") "Beilstein:1915399") -AnnotationAssertion(Annotation( "Beilstein") "Beilstein:3653705") -AnnotationAssertion(Annotation( "ChemIDplus") "CAS:58-22-0") -AnnotationAssertion(Annotation( "KEGG COMPOUND") "CAS:58-22-0") -AnnotationAssertion(Annotation( "NIST Chemistry WebBook") "CAS:58-22-0") -AnnotationAssertion( "DrugBank:DB00624") -AnnotationAssertion(Annotation( "DrugCentral") "Drug_Central:2607") -AnnotationAssertion(Annotation( "Gmelin") "Gmelin:538843") -AnnotationAssertion( "HMDB:HMDB0000234") -AnnotationAssertion( "KEGG:C00535") -AnnotationAssertion( "KEGG:D00075") -AnnotationAssertion( "KNApSAcK:C00003675") -AnnotationAssertion(Annotation( "LIPID MAPS") "LIPID_MAPS_instance:LMST02020002") -AnnotationAssertion( "PDBeChem:TES") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:10438974") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:11786693") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:18900503") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:24498482") -AnnotationAssertion(Annotation( "Reaxys") "Reaxys:1915399") -AnnotationAssertion( "Wikipedia:Testosterone") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "17beta-hydroxyandrost-4-en-3-one") -AnnotationAssertion(Annotation( "PDBeChem") "TESTOSTERONE") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Testosterone") -AnnotationAssertion(Annotation( "UniProt") "testosterone") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "17beta-Hydroxy-4-androsten-3-one") -AnnotationAssertion(Annotation( "ChEBI") "17beta-hydroxy-4-androsten-3-one") -AnnotationAssertion(Annotation( "NIST_Chemistry_WebBook") "4-androsten-17beta-ol-3-one") -AnnotationAssertion(Annotation( "ChemIDplus") "Androderm") -AnnotationAssertion(Annotation( "ChemIDplus") "Testosteron") -AnnotationAssertion(Annotation( "ChemIDplus") Annotation( ) "testosterona") -AnnotationAssertion(Annotation( "ChemIDplus") Annotation( ) "testosterone") -AnnotationAssertion(Annotation( "ChemIDplus") Annotation( ) "testosteronum") -AnnotationAssertion( "CHEBI:17347") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "testosterone") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (aldehyde) - -AnnotationAssertion( "A compound RC(=O)H, in which a carbonyl group is bonded to one hydrogen atom and to one R group.") -AnnotationAssertion( "0") -AnnotationAssertion( "CHOR") -AnnotationAssertion( "29.01800") -AnnotationAssertion( "29.00274") -AnnotationAssertion( "[H]C([*])=O") -AnnotationAssertion( "CHEBI:13432") -AnnotationAssertion( "CHEBI:13753") -AnnotationAssertion( "CHEBI:13805") -AnnotationAssertion( "CHEBI:13806") -AnnotationAssertion( "CHEBI:22291") -AnnotationAssertion( "CHEBI:2554") -AnnotationAssertion( "CHEBI:8750") -AnnotationAssertion( "KEGG:C00071") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Aldehyde") -AnnotationAssertion(Annotation( "ChEBI") "aldehyde") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "aldehyde") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "aldehydes") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "Aldehyd") -AnnotationAssertion(Annotation( "IUPAC") "RC(=O)H") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "RCHO") -AnnotationAssertion(Annotation( "ChEBI") "aldehido") -AnnotationAssertion(Annotation( "ChEBI") "aldehidos") -AnnotationAssertion(Annotation( "ChEBI") "aldehydes") -AnnotationAssertion(Annotation( "ChEBI") "aldehydum") -AnnotationAssertion(Annotation( "UniProt") "an aldehyde") -AnnotationAssertion( "CHEBI:17478") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "aldehyde") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (hydrogencarbonate) AnnotationAssertion( "The carbon oxoanion resulting from the removal of a proton from carbonic acid.") @@ -19409,47 +9216,6 @@ SubClassOf( ObjectSomeValuesFrom( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (geroprotector) - -AnnotationAssertion( "Any compound that supports healthy aging, slows the biological aging process, or extends lifespan.") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:23372317") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:28580190") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:30885572") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:33144142") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:33973253") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:34606237") -AnnotationAssertion( "Wikipedia:Geroprotector") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "anti-aging agent") -AnnotationAssertion(Annotation( "ChEBI") "anti-aging agents") -AnnotationAssertion(Annotation( "ChEBI") "anti-aging drug") -AnnotationAssertion(Annotation( "ChEBI") "anti-aging drugs") -AnnotationAssertion(Annotation( "ChEBI") "geroprotective agent") -AnnotationAssertion(Annotation( "ChEBI") "geroprotective agents") -AnnotationAssertion(Annotation( "ChEBI") "geroprotectors") -AnnotationAssertion( "CHEBI:176497") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "geroprotector") -SubClassOf( ) - -# Class: (ribonucleoside diphosphate) - -AnnotationAssertion( "0") -AnnotationAssertion( "C5H11O10P2R") -AnnotationAssertion( "293.083") -AnnotationAssertion( "292.98274") -AnnotationAssertion( "CHEBI:15046") -AnnotationAssertion( "CHEBI:26557") -AnnotationAssertion( "CHEBI:8845") -AnnotationAssertion( "KEGG:C03723") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Ribonucleoside diphosphate") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "ribonucleoside diphosphates") -AnnotationAssertion( "CHEBI:17668") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "ribonucleoside diphosphate") -SubClassOf( ) - # Class: (ceramide) AnnotationAssertion( "Ceramides (N-acyl-sphingoid bases) are a major subclass of sphingoid base derivatives with an amide-linked fatty acid. The fatty acids are typically saturated or monounsaturated with chain lengths from 14 to 26 carbon atoms; the presence of a hydroxyl group on carbon 2 is fairly common. Ceramides are generally precursors of more complex sphingolipids. In the illustrated generalised structure, R(1) = OH, OX (where X = acyl, glycosyl, phosphate, phosphonate, etc.), or H.") @@ -19493,69 +9259,6 @@ AnnotationAssertion( "donor") SubClassOf( ) -# Class: (butyrate) - -AnnotationAssertion( "A short-chain fatty acid anion that is the conjugate base of butyric acid, obtained by deprotonation of the carboxy group.") -AnnotationAssertion( "-1") -AnnotationAssertion( "C4H7O2") -AnnotationAssertion( "InChI=1S/C4H8O2/c1-2-3-4(5)6/h2-3H2,1H3,(H,5,6)/p-1") -AnnotationAssertion( "FERIUCNNQQJTOY-UHFFFAOYSA-M") -AnnotationAssertion( "87.09718") -AnnotationAssertion( "87.04515") -AnnotationAssertion( "CCCC([O-])=O") -AnnotationAssertion( "CHEBI:13924") -AnnotationAssertion( "CHEBI:22946") -AnnotationAssertion(Annotation( "Beilstein") "Beilstein:3601060") -AnnotationAssertion(Annotation( "ChemIDplus") "CAS:461-55-2") -AnnotationAssertion(Annotation( "Gmelin") "Gmelin:324289") -AnnotationAssertion( "KEGG:C00246") -AnnotationAssertion( "MetaCyc:BUTYRIC_ACID") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:17190852") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:7496326") -AnnotationAssertion(Annotation( "Reaxys") "Reaxys:3601060") -AnnotationAssertion(Annotation( "UM-BBD") "UM-BBD_compID:c0035") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "butanoate") -AnnotationAssertion(Annotation( "IUPAC") "butyrate") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "1-butanoate") -AnnotationAssertion(Annotation( "ChEBI") "1-butyrate") -AnnotationAssertion(Annotation( "ChEBI") "1-propanecarboxylate") -AnnotationAssertion(Annotation( "IUPAC") "CH3-[CH2]2-COO(-)") -AnnotationAssertion(Annotation( "ChEBI") "butanate") -AnnotationAssertion(Annotation( "ChEBI") "butanoate") -AnnotationAssertion(Annotation( "UniProt") "butanoate") -AnnotationAssertion(Annotation( "ChemIDplus") "butanoic acid, ion(1-)") -AnnotationAssertion(Annotation( "ChEBI") "n-butanoate") -AnnotationAssertion(Annotation( "ChemIDplus") "n-butyrate") -AnnotationAssertion(Annotation( "ChEBI") "propanecarboxylate") -AnnotationAssertion(Annotation( "ChEBI") "propylformate") -AnnotationAssertion( "CHEBI:17968") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "butyrate") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (ribonucleoside triphosphate) - -AnnotationAssertion( "0") -AnnotationAssertion( "C5H12O13P3R") -AnnotationAssertion( "373.063") -AnnotationAssertion( "372.94908") -AnnotationAssertion( "CHEBI:15047") -AnnotationAssertion( "CHEBI:26559") -AnnotationAssertion( "CHEBI:8846") -AnnotationAssertion( "KEGG:C03802") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Ribonucleoside triphosphate") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "ribonucleoside triphosphates") -AnnotationAssertion( "CHEBI:17972") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "ribonucleoside triphosphate") -SubClassOf( ) - # Class: (lipid) AnnotationAssertion( "'Lipids' is a loosely defined term for substances of biological origin that are soluble in nonpolar solvents. They consist of saponifiable lipids, such as glycerides (fats and oils) and phospholipids, as well as nonsaponifiable lipids, principally steroids.") @@ -19591,24 +9294,6 @@ AnnotationAssertion( "glycosaminoglycan") SubClassOf( ) -# Class: (hexose) - -AnnotationAssertion( "Any six-carbon monosaccharide which in its linear form contains either an aldehyde group at position 1 (aldohexose) or a ketone group at position 2 (ketohexose).") -AnnotationAssertion( "CHEBI:14399") -AnnotationAssertion( "CHEBI:24590") -AnnotationAssertion( "CHEBI:5709") -AnnotationAssertion( "GlyGen:G70994MS") -AnnotationAssertion( "GlyTouCan:G70994MS") -AnnotationAssertion( "KEGG:C00738") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Hexose") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "GlyTouCan") "WURCS=2.0/1,1,0/[axxxxh-1x_1-5_2*NCC/3=O]/1/") -AnnotationAssertion(Annotation( "ChEBI") "hexoses") -AnnotationAssertion( "CHEBI:18133") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "hexose") -SubClassOf( ) - # Class: (polysaccharide) AnnotationAssertion( "A biomacromolecule consisting of large numbers of monosaccharide residues linked glycosidically. This term is commonly used only for those containing more than ten monosaccharide residues.") @@ -19633,244 +9318,6 @@ SubClassOf( ) SubClassOf( ) -# Class: (glutamic acid) - -AnnotationAssertion( "An alpha-amino acid that is glutaric acid bearing a single amino substituent at position 2.") -AnnotationAssertion( "0") -AnnotationAssertion( "C5H9NO4") -AnnotationAssertion( "InChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)") -AnnotationAssertion( "WHUUTDBJXJRKMK-UHFFFAOYSA-N") -AnnotationAssertion( "147.12930") -AnnotationAssertion( "147.05316") -AnnotationAssertion( "NC(CCC(O)=O)C(O)=O") -AnnotationAssertion( "CHEBI:24314") -AnnotationAssertion( "CHEBI:5431") -AnnotationAssertion(Annotation( "Beilstein") "Beilstein:1723799") -AnnotationAssertion(Annotation( "ChemIDplus") "CAS:617-65-2") -AnnotationAssertion(Annotation( "KEGG COMPOUND") "CAS:617-65-2") -AnnotationAssertion(Annotation( "NIST Chemistry WebBook") "CAS:617-65-2") -AnnotationAssertion(Annotation( "Gmelin") "Gmelin:101971") -AnnotationAssertion( "KEGG:C00302") -AnnotationAssertion( "KEGG:D04341") -AnnotationAssertion( "KNApSAcK:C00001358") -AnnotationAssertion( "KNApSAcK:C00019577") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:15739367") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:17190852") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:24616376") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:24984001") -AnnotationAssertion(Annotation( "Reaxys") "Reaxys:1723799") -AnnotationAssertion( "Wikipedia:Glutamic_acid") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "2-aminopentanedioic acid") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Glutamic acid") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "glutamic acid") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "2-Aminoglutaric acid") -AnnotationAssertion(Annotation( "KEGG_DRUG") "DL-Glutamic acid") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "DL-Glutaminic acid") -AnnotationAssertion(Annotation( "ChEBI") "E") -AnnotationAssertion(Annotation( "ChEBI") "Glu") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Glutamate") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Glutaminic acid") -AnnotationAssertion(Annotation( "ChEBI") "Glutaminsaeure") -AnnotationAssertion( "CHEBI:18237") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "glutamic acid") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (dopamine) - -AnnotationAssertion( "Catechol in which the hydrogen at position 4 is substituted by a 2-aminoethyl group.") -AnnotationAssertion( "0") -AnnotationAssertion( "C8H11NO2") -AnnotationAssertion( "InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2") -AnnotationAssertion( "VYFYYTLLBUKUHU-UHFFFAOYSA-N") -AnnotationAssertion( "153.17840") -AnnotationAssertion( "153.07898") -AnnotationAssertion( "NCCc1ccc(O)c(O)c1") -AnnotationAssertion( "CHEBI:11695") -AnnotationAssertion( "CHEBI:11930") -AnnotationAssertion( "CHEBI:14203") -AnnotationAssertion( "CHEBI:1764") -AnnotationAssertion( "CHEBI:23886") -AnnotationAssertion( "CHEBI:43686") -AnnotationAssertion(Annotation( "ChemIDplus") "CAS:51-61-6") -AnnotationAssertion( "DrugBank:DB00988") -AnnotationAssertion(Annotation( "DrugCentral") "Drug_Central:947") -AnnotationAssertion( "HMDB:HMDB0000073") -AnnotationAssertion( "KEGG:C03758") -AnnotationAssertion( "KEGG:D07870") -AnnotationAssertion( "KNApSAcK:C00001408") -AnnotationAssertion( "LINCS:LSM-4630") -AnnotationAssertion( "MetaCyc:DOPAMINE") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:10629745") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:11149432") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:9422813") -AnnotationAssertion(Annotation( "Reaxys") "Reaxys:1072822") -AnnotationAssertion( "Wikipedia:Dopamine") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "4-(2-aminoethyl)benzene-1,2-diol") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Dopamine") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "2-(3,4-Dihydroxyphenyl)ethylamine") -AnnotationAssertion(Annotation( "ChEBI") "2-(3,4-dihydroxyphenyl)ethylamine") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "3,4-Dihydroxyphenethylamine") -AnnotationAssertion(Annotation( "ChemIDplus") "3-Hydroxytyramine") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "4-(2-Aminoethyl)-1,2-benzenediol") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "4-(2-Aminoethyl)benzene-1,2-diol") -AnnotationAssertion(Annotation( "ChEBI") "4-(2-aminoethyl)-1,2-benzenediol") -AnnotationAssertion(Annotation( "ChemIDplus") "4-(2-aminoethyl)catechol") -AnnotationAssertion(Annotation( "ChemIDplus") "4-(2-aminoethyl)pyrocatechol") -AnnotationAssertion(Annotation( "DrugBank") "Deoxyepinephrine") -AnnotationAssertion(Annotation( "DrugBank") "Hydroxytyramin") -AnnotationAssertion(Annotation( "ChemIDplus") Annotation( ) "dopamina") -AnnotationAssertion(Annotation( "ChEBI") Annotation( ) "dopamine") -AnnotationAssertion(Annotation( "ChemIDplus") Annotation( ) "dopaminum") -AnnotationAssertion( "CHEBI:18243") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "dopamine") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (iron atom) - -AnnotationAssertion( "An iron group element atom that has atomic number 26.") -AnnotationAssertion( "0") -AnnotationAssertion( "Fe") -AnnotationAssertion( "InChI=1S/Fe") -AnnotationAssertion( "XEEYBQQBJWHFJM-UHFFFAOYSA-N") -AnnotationAssertion( "55.84500") -AnnotationAssertion( "55.93494") -AnnotationAssertion( "[Fe]") -AnnotationAssertion( "CHEBI:13322") -AnnotationAssertion( "CHEBI:24872") -AnnotationAssertion( "CHEBI:5974") -AnnotationAssertion(Annotation( "ChemIDplus") "CAS:7439-89-6") -AnnotationAssertion(Annotation( "KEGG COMPOUND") "CAS:7439-89-6") -AnnotationAssertion(Annotation( "NIST Chemistry WebBook") "CAS:7439-89-6") -AnnotationAssertion( "DrugBank:DB01592") -AnnotationAssertion( "HMDB:HMDB0015531") -AnnotationAssertion( "KEGG:C00023") -AnnotationAssertion(Annotation( "Reaxys") "Reaxys:4122945") -AnnotationAssertion( "WebElements:Fe") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "iron") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "IUPAC") "26Fe") -AnnotationAssertion(Annotation( "ChEBI") "Eisen") -AnnotationAssertion(Annotation( "IUPAC") "Fe") -AnnotationAssertion(Annotation( "UniProt") "Fe") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Iron") -AnnotationAssertion(Annotation( "ChEBI") "fer") -AnnotationAssertion(Annotation( "IUPAC") "ferrum") -AnnotationAssertion(Annotation( "ChEBI") "hierro") -AnnotationAssertion(Annotation( "ChEBI") "iron") -AnnotationAssertion( "CHEBI:18248") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "iron atom") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (ribonucleoside) - -AnnotationAssertion( "Any nucleoside where the sugar component is D-ribose.") -AnnotationAssertion( "0") -AnnotationAssertion( "C5H9O4R") -AnnotationAssertion( "133.123") -AnnotationAssertion( "133.05008") -AnnotationAssertion( "OC[C@H]1O[C@@H]([*])[C@H](O)[C@@H]1O") -AnnotationAssertion( "CHEBI:13014") -AnnotationAssertion( "CHEBI:13015") -AnnotationAssertion( "CHEBI:13685") -AnnotationAssertion( "CHEBI:21085") -AnnotationAssertion( "CHEBI:26560") -AnnotationAssertion( "CHEBI:4240") -AnnotationAssertion( "CHEBI:8844") -AnnotationAssertion( "KEGG:C00911") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Ribonucleoside") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "UniProt") "a ribonucleoside") -AnnotationAssertion(Annotation( "ChEBI") "ribonucleosides") -AnnotationAssertion( "CHEBI:18254") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "ribonucleoside") -SubClassOf( ) -SubClassOf( ) - -# Class: (nucleobase) - -AnnotationAssertion( "That part of DNA or RNA that may be involved in pairing.") -AnnotationAssertion( "CHEBI:13873") -AnnotationAssertion( "CHEBI:25598") -AnnotationAssertion( "CHEBI:2995") -AnnotationAssertion( "KEGG:C00701") -AnnotationAssertion( "Wikipedia:Nucleobase") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Base") -AnnotationAssertion(Annotation( "ChEBI") "nucleobases") -AnnotationAssertion( "CHEBI:18282") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "nucleobase") -SubClassOf( ) - -# Class: (histamine) - -AnnotationAssertion( "A member of the class of imidazoles that is 1H-imidazole substituted at position C-4 by a 2-aminoethyl group.") -AnnotationAssertion( "0") -AnnotationAssertion( "C5H9N3") -AnnotationAssertion( "InChI=1S/C5H9N3/c6-2-1-5-3-7-4-8-5/h3-4H,1-2,6H2,(H,7,8)") -AnnotationAssertion( "NTYJJOPFIAHURM-UHFFFAOYSA-N") -AnnotationAssertion( "111.14518") -AnnotationAssertion( "111.07965") -AnnotationAssertion( "NCCc1c[nH]cn1") -AnnotationAssertion( "CHEBI:14401") -AnnotationAssertion( "CHEBI:24596") -AnnotationAssertion( "CHEBI:43187") -AnnotationAssertion( "CHEBI:817") -AnnotationAssertion(Annotation( "Beilstein") "Beilstein:2012") -AnnotationAssertion(Annotation( "ChemIDplus") "CAS:51-45-6") -AnnotationAssertion(Annotation( "KEGG COMPOUND") "CAS:51-45-6") -AnnotationAssertion(Annotation( "NIST Chemistry WebBook") "CAS:51-45-6") -AnnotationAssertion(Annotation( "DrugCentral") "Drug_Central:1375") -AnnotationAssertion(Annotation( "Gmelin") "Gmelin:2968") -AnnotationAssertion( "HMDB:HMDB0000870") -AnnotationAssertion( "KEGG:C00388") -AnnotationAssertion( "KEGG:D08040") -AnnotationAssertion( "KNApSAcK:C00001414") -AnnotationAssertion( "MetaCyc:HISTAMINE") -AnnotationAssertion( "PDBeChem:HSM") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:16399866") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:19547708") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:19843401") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:22770225") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:24101735") -AnnotationAssertion(Annotation( "Reaxys") "Reaxys:2012") -AnnotationAssertion( "Wikipedia:Histamine") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "2-(1H-imidazol-4-yl)ethanamine") -AnnotationAssertion(Annotation( "PDBeChem") "HISTAMINE") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Histamine") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "1H-Imidazole-4-ethanamine") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "2-(4-Imidazolyl)ethylamine") -AnnotationAssertion( "CHEBI:18295") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "histamine") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (alkane) AnnotationAssertion( "An acyclic branched or unbranched hydrocarbon having the general formula CnH2n+2, and therefore consisting entirely of hydrogen atoms and saturated carbon atoms.") @@ -19900,64 +9347,6 @@ AnnotationAssertion(rdfs:label "alk SubClassOf( ) SubClassOf( ) -# Class: ((R)-noradrenaline) - -AnnotationAssertion( "The R-enantiomer of noradrenaline.") -AnnotationAssertion( "0") -AnnotationAssertion( "C8H11NO3") -AnnotationAssertion( "InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2/t8-/m0/s1") -AnnotationAssertion( "SFLSHLFXELFNJZ-QMMMGPOBSA-N") -AnnotationAssertion( "169.17780") -AnnotationAssertion( "169.07389") -AnnotationAssertion( "NC[C@H](O)c1ccc(O)c(O)c1") -AnnotationAssertion( "CHEBI:1") -AnnotationAssertion( "CHEBI:14668") -AnnotationAssertion( "CHEBI:25592") -AnnotationAssertion( "CHEBI:258884") -AnnotationAssertion( "CHEBI:43725") -AnnotationAssertion(Annotation( "Beilstein") "Beilstein:2804840") -AnnotationAssertion(Annotation( "ChemIDplus") "Beilstein:4231961") -AnnotationAssertion(Annotation( "ChemIDplus") "CAS:51-41-2") -AnnotationAssertion(Annotation( "KEGG COMPOUND") "CAS:51-41-2") -AnnotationAssertion( "DrugBank:DB00368") -AnnotationAssertion(Annotation( "DrugCentral") "Drug_Central:1960") -AnnotationAssertion( "HMDB:HMDB0000216") -AnnotationAssertion( "KEGG:C00547") -AnnotationAssertion( "KEGG:D00076") -AnnotationAssertion( "KNApSAcK:C00001424") -AnnotationAssertion( "PDBeChem:LNR") -AnnotationAssertion(Annotation( "Reaxys") "Reaxys:2804840") -AnnotationAssertion( "Wikipedia:Norepinephrine") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "4-[(1R)-2-amino-1-hydroxyethyl]benzene-1,2-diol") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChemIDplus") "(-)-arterenol") -AnnotationAssertion(Annotation( "IUPHAR") "(-)-noradrenaline") -AnnotationAssertion(Annotation( "ChemIDplus") "(-)-norepinephrine") -AnnotationAssertion(Annotation( "ChemIDplus") "(R)-(-)-norepinephrine") -AnnotationAssertion(Annotation( "ChemIDplus") "(R)-4-(2-amino-1-hydroxyethyl)-1,2-benzenediol") -AnnotationAssertion(Annotation( "ChemIDplus") "(R)-norepinephrine") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "4-[(1R)-2-Amino-1-hydroxyethyl]-1,2-benzenediol") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Arterenol") -AnnotationAssertion(Annotation( "PDBeChem") "L-NOREPINEPHRINE") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "L-Noradrenaline") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Noradrenaline") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Norepinephrine") -AnnotationAssertion(Annotation( "ChEBI") Annotation( ) "norepinefrina") -AnnotationAssertion(Annotation( "ChemIDplus") Annotation( ) "norepinephrine") -AnnotationAssertion(Annotation( "WHO_MedNet") Annotation( ) "norepinephrine") -AnnotationAssertion(Annotation( "ChEBI") Annotation( ) "norepinephrinum") -AnnotationAssertion( "CHEBI:18357") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "(R)-noradrenaline") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (phosphate(3-)) AnnotationAssertion( "A phosphate ion that is the conjugate base of hydrogenphosphate.") @@ -20006,53 +9395,6 @@ AnnotationAssertion(rdfs:label "in SubClassOf( ) SubClassOf( ) -# Class: (4-[1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol) - -AnnotationAssertion( "A catecholamine in which the aminoethyl side-chain is hydroxy-substituted at C-1 and methylated on nitrogen.") -AnnotationAssertion( "0") -AnnotationAssertion( "C9H13NO3") -AnnotationAssertion( "InChI=1S/C9H13NO3/c1-10-5-9(13)6-2-3-7(11)8(12)4-6/h2-4,9-13H,5H2,1H3") -AnnotationAssertion( "UCTWMZQNUQWSLP-UHFFFAOYSA-N") -AnnotationAssertion( "183.207") -AnnotationAssertion( "183.08954") -AnnotationAssertion( "CNCC(O)C1=CC(O)=C(O)C=C1") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "4-[1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion( "CHEBI:194548") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "4-[1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol") -SubClassOf( ) - -# Class: (5beta-cholane) - -AnnotationAssertion( "0") -AnnotationAssertion( "C24H42") -AnnotationAssertion( "InChI=1S/C24H42/c1-5-8-17(2)20-12-13-21-19-11-10-18-9-6-7-15-23(18,3)22(19)14-16-24(20,21)4/h17-22H,5-16H2,1-4H3/t17-,18+,19+,20-,21+,22+,23+,24-/m1/s1") -AnnotationAssertion( "QSHQKIURKJITMZ-OBUPQJQESA-N") -AnnotationAssertion( "330.59028") -AnnotationAssertion( "330.32865") -AnnotationAssertion( "[H][C@@]12CCCC[C@]1(C)[C@@]1([H])CC[C@]3(C)[C@]([H])(CC[C@@]3([H])[C@]1([H])CC2)[C@H](C)CCC") -AnnotationAssertion(Annotation( "Beilstein") "Beilstein:2048472") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "5beta-cholane") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion( "CHEBI:20664") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "5beta-cholane") -SubClassOf( ) - -# Class: (6-aminopurines) - -AnnotationAssertion( "Any compound having 6-aminopurine (adenine) as part of its structure.") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:1646334") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:18524423") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:7342604") -AnnotationAssertion(Annotation( "ChEBI") "6-aminopurines") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion( "CHEBI:20706") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "6-aminopurines") -SubClassOf( ) - # Class: (N-acylglucosamine) AnnotationAssertion(Annotation( "ChEBI") "N-acylglucosamine") @@ -20074,31 +9416,6 @@ AnnotationAssertion( "N-acyl-hexosamine") SubClassOf( ) -# Class: (N-glycosyl compound) - -AnnotationAssertion( "A glycosyl compound arising formally from the elimination of water from a glycosidic hydroxy group and an H atom bound to a nitrogen atom, thus creating a C-N bond.") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "glycosylamine") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "N-glycoside") -AnnotationAssertion(Annotation( "ChEBI") "N-glycosides") -AnnotationAssertion(Annotation( "ChEBI") "N-glycosyl compounds") -AnnotationAssertion(Annotation( "IUPAC") "glycosylamines") -AnnotationAssertion( "CHEBI:21731") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "N-glycosyl compound") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (acetamides) - -AnnotationAssertion( "Compounds with the general formula RNHC(=O)CH3.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion( "CHEBI:22160") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "acetamides") -SubClassOf( ) - # Class: (acyl group) AnnotationAssertion( "An organic group formed by removing one or more hydroxy groups from an oxoacid that has the general structure RkE(=O)l(OH)m (l =/= 0). Although the term is almost always applied to organic compounds, with carboxylic acid as the oxoacid, acyl groups can in principle be derived from other types of acids such as sulfonic acids or phosphonic acids.") @@ -20113,27 +9430,6 @@ AnnotationAssertion( "acyl group") SubClassOf( ) -# Class: (adenosine phosphate) - -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "adenosine phosphates") -AnnotationAssertion( "CHEBI:22256") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "adenosine phosphate") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (adenosines) - -AnnotationAssertion( "Any purine ribonucleoside that is a derivative of adenosine.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion( "CHEBI:22260") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "adenosines") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (alkaline earth metal atom) AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "alkaline earth metals") @@ -20172,22 +9468,6 @@ SubClassOf( ) SubClassOf( ) -# Class: (alkaloid) - -AnnotationAssertion( "Any of the naturally occurring, basic nitrogen compounds (mostly heterocyclic) occurring mostly in the plant kingdom, but also found in bacteria, fungi, and animals. By extension, certain neutral compounds biogenetically related to basic alkaloids are also classed as alkaloids. Amino acids, peptides, proteins, nucleotides, nucleic acids, amino sugars and antibiotics are not normally regarded as alkaloids. Compounds in which the nitrogen is exocyclic (dopamine, mescaline, serotonin, etc.) are usually classed as amines rather than alkaloids.") -AnnotationAssertion( "Wikipedia:Alkaloid") -AnnotationAssertion(Annotation( "ChEBI") "Alkaloid") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "alkaloids") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "Alkaloide") -AnnotationAssertion(Annotation( "ChEBI") "alcaloide") -AnnotationAssertion(Annotation( "ChEBI") "alcaloides") -AnnotationAssertion( "CHEBI:22315") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "alkaloid") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (aminoglycan) AnnotationAssertion( "chebi_ontology") @@ -20198,16 +9478,6 @@ AnnotationAssertion(rdfs:label "ami SubClassOf( ) SubClassOf( ) -# Class: (aminopurine) - -AnnotationAssertion( "Any purine having at least one amino substituent.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "aminopurines") -AnnotationAssertion( "CHEBI:22527") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "aminopurine") -SubClassOf( ) - # Class: (anion) AnnotationAssertion( "A monoatomic or polyatomic species having one or more elementary charges of the electron.") @@ -20253,17 +9523,6 @@ AnnotationAssertion( "base") SubClassOf( ) -# Class: (benzopyrrole) - -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "benzopyrroles") -AnnotationAssertion( "CHEBI:22728") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "benzopyrrole") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - # Class: (bile salt) AnnotationAssertion( "A sodium salt of the conjugate of any bile acid with either glycine or taurine.") @@ -20487,27 +9746,6 @@ AnnotationAssertion( "cyclic peptide") SubClassOf( ) -# Class: (diazole) - -AnnotationAssertion( "An azole that is either one of a pair of heterocyclic organic compounds comprising three carbon atoms and two nitrogen atoms arranged in a ring.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "diazoles") -AnnotationAssertion( "CHEBI:23677") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "diazole") -SubClassOf( ) - -# Class: (({[(2R,3S,4R,5R)-3,4-dihydroxy-5-(9H-purin-9-yl)oxolan-2-yl]methyl phosphonato}oxy)(phosphonatooxy)phosphinate) - -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion( "CHEBI:237958") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "({[(2R,3S,4R,5R)-3,4-dihydroxy-5-(9H-purin-9-yl)oxolan-2-yl]methyl phosphonato}oxy)(phosphonatooxy)phosphinate") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (drug) AnnotationAssertion( "Any substance which when absorbed into a living organism may modify one or more of its functions. The term is generally accepted for a substance taken for a therapeutic purpose, but is also commonly used for abused substances.") @@ -20545,16 +9783,6 @@ AnnotationAssertion(rdfs:label "enz SubClassOf( ) SubClassOf( ) -# Class: (glucocorticoid) - -AnnotationAssertion( "Glucocorticoids are a class of steroid hormones that regulate a variety of physiological processes, in particular control of the concentration of glucose in blood.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "glucocorticoids") -AnnotationAssertion( "CHEBI:24261") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "glucocorticoid") -SubClassOf( ) - # Class: (glucosamines) AnnotationAssertion( "Any hexosamine that is glucose in which at least one of the hydroxy groups has been replaced by an amino group.") @@ -20564,51 +9792,6 @@ AnnotationAssertion( "glucosamines") SubClassOf( ) -# Class: (glutamine family amino acid) - -AnnotationAssertion( "An L-alpha-amino acid which is L-glutamic acid or any of the essential amino acids biosynthesised from it (glutamine, proline and arginine). A closed class.") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:20716061") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "glutamine family amino acids") -AnnotationAssertion( "CHEBI:24318") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "glutamine family amino acid") -SubClassOf( ) -SubClassOf( ) - -# Class: (EC 6.3.1.2 (glutamate--ammonia ligase) inhibitor) - -AnnotationAssertion( "An EC 6.3.* (C-N bond-forming ligase) inhibitor that interferes with the action of glutamate--ammonia ligase (EC 6.3.1.2).") -AnnotationAssertion( "Wikipedia:Glutamine_synthetase") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "EC 6.3.1.2 (glutamate--ammonia ligase) inhibitors") -AnnotationAssertion(Annotation( "ChEBI") "EC 6.3.1.2 inhibitor") -AnnotationAssertion(Annotation( "ChEBI") "EC 6.3.1.2 inhibitors") -AnnotationAssertion(Annotation( "ChEBI") "L-glutamate:ammonia ligase (ADP-forming) inhibitor") -AnnotationAssertion(Annotation( "ChEBI") "L-glutamate:ammonia ligase (ADP-forming) inhibitors") -AnnotationAssertion(Annotation( "ChEBI") "L-glutamine synthetase inhibitor") -AnnotationAssertion(Annotation( "ChEBI") "L-glutamine synthetase inhibitors") -AnnotationAssertion(Annotation( "ChEBI") "glutamate--ammonia ligase (EC 6.3.1.2) inhibitor") -AnnotationAssertion(Annotation( "ChEBI") "glutamate--ammonia ligase (EC 6.3.1.2) inhibitors") -AnnotationAssertion(Annotation( "ChEBI") "glutamate--ammonia ligase inhibitor") -AnnotationAssertion(Annotation( "ChEBI") "glutamate--ammonia ligase inhibitors") -AnnotationAssertion(Annotation( "ChEBI") "glutamine synthetase inhibitor") -AnnotationAssertion(Annotation( "ChEBI") "glutamine synthetase inhibitors") -AnnotationAssertion(Annotation( "ChEBI") "glutamylhydroxamic synthetase inhibitor") -AnnotationAssertion(Annotation( "ChEBI") "glutamylhydroxamic synthetase inhibitors") -AnnotationAssertion( "CHEBI:24319") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "EC 6.3.1.2 (glutamate--ammonia ligase) inhibitor") -SubClassOf( ) - -# Class: (glycogens) - -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion( "CHEBI:24384") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "glycogens") -SubClassOf( ) - # Class: (glycosphingolipid) AnnotationAssertion( "A glycosphingolipid is a glycolipid that is a carbohydrate-containing derivative of a sphingoid or ceramide. It is understood that the carbohydrate residue is attached by a glycosidic linkage to O-1 of the sphingoid.") @@ -20741,36 +9924,6 @@ SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (hydroxy-5beta-cholanic acid) - -AnnotationAssertion( "Any member of the class of 5beta-cholanic acids carrying at least one hydroxy group at unspecified position.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "hydroxy-5beta-cholanic acids") -AnnotationAssertion( "CHEBI:24663") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "hydroxy-5beta-cholanic acid") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (imidazoles) - -AnnotationAssertion( "A five-membered organic heterocycle containing two nitrogen atoms at positions 1 and 3, or any of its derivatives; compounds containing an imidazole skeleton.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion( "CHEBI:24780") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "imidazoles") -SubClassOf( ) - -# Class: (indoles) - -AnnotationAssertion( "Any compound containing an indole skeleton.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion( "CHEBI:24828") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "indoles") -SubClassOf( ) - # Class: (oxoacid) AnnotationAssertion( "A compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons).") @@ -20889,34 +10042,6 @@ AnnotationAssertion( "ion") SubClassOf( ) -# Class: (iron molecular entity) - -AnnotationAssertion(Annotation( "ChEBI") "iron molecular entity") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "iron compounds") -AnnotationAssertion(Annotation( "ChEBI") "iron molecular entities") -AnnotationAssertion( "CHEBI:24873") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "iron molecular entity") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (iron cation) - -AnnotationAssertion( "Fe") -AnnotationAssertion( "55.845") -AnnotationAssertion( "55.93494") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "iron cation") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "UniProt") "Fe cation") -AnnotationAssertion(Annotation( "ChEBI") "iron cations") -AnnotationAssertion( "CHEBI:24875") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "iron cation") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (isoprenoid) AnnotationAssertion( "Any lipid formally derived from isoprene (2-methylbuta-1,3-diene), the skeleton of which can generally be discerned in repeated occurrence in the molecule. The skeleton of isoprenoids may differ from strict additivity of isoprene units by loss or shift of a fragment, commonly a methyl group. The class includes both hydrocarbons and oxygenated derivatives.") @@ -20979,28 +10104,6 @@ AnnotationAssertion(rdfs:label "met SubClassOf( ) SubClassOf( ) -# Class: (mineralocorticoid) - -AnnotationAssertion( "Mineralocorticoids are a class of steroid hormones that regulate water and electrolyte metabolism.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "mineralocorticoids") -AnnotationAssertion( "CHEBI:25354") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "mineralocorticoid") -SubClassOf( ) - -# Class: (elemental molecule) - -AnnotationAssertion( "A molecule all atoms of which have the same atomic number.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "homoatomic molecule") -AnnotationAssertion(Annotation( "ChEBI") "homoatomic molecules") -AnnotationAssertion( "CHEBI:25362") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "elemental molecule") -SubClassOf( ) -SubClassOf( ) - # Class: (molecule) AnnotationAssertion( "Any polyatomic entity that is an electrically neutral entity consisting of more than one atom.") @@ -21015,29 +10118,6 @@ AnnotationAssertion( "molecule") SubClassOf( ) -# Class: (monoamine molecular messenger) - -AnnotationAssertion( "A group of neurotransmitters and neuromodulators that contain one amino group that is connected to an aromatic ring by ethylene group (-CH2-CH2-). Monoamines are derived from the aromatic amino acids phenylalanine, tyrosine, histidine and tryptophan.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "monamines") -AnnotationAssertion(Annotation( "ChEBI") "monoamines") -AnnotationAssertion( "CHEBI:25375") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "monoamine molecular messenger") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (monocarboxylic acid) - -AnnotationAssertion( "An oxoacid containing a single carboxy group.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "monocarboxylic acids") -AnnotationAssertion( "CHEBI:25384") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "monocarboxylic acid") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (monoatomic monocation) AnnotationAssertion( "+1") @@ -21112,32 +10192,6 @@ AnnotationAssertion( "nonmetal atom") SubClassOf( ) -# Class: (nucleoside phosphate) - -AnnotationAssertion( "A nucleobase-containing molecular entity that is a nucleoside in which one or more of the sugar hydroxy groups has been converted into a mono- or poly-phosphate. The term includes both nucleotides and non-nucleotide nucleoside phosphates.") -AnnotationAssertion( "KEGG:C01329") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "NMP") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Nucleoside monophosphate") -AnnotationAssertion(Annotation( "ChEBI") "nucleoside phosphates") -AnnotationAssertion( "CHEBI:25608") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "nucleoside phosphate") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (organic heteromonocyclic compound) - -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "organic heteromonocyclic compounds") -AnnotationAssertion( "CHEBI:25693") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "organic heteromonocyclic compound") -SubClassOf( ) -SubClassOf( ) - # Class: (organic anion) AnnotationAssertion( "Any organic ion with a net negative charge.") @@ -21272,28 +10326,6 @@ AnnotationAssertion(rdfs:label "oxy SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (aldopentose phosphate) - -AnnotationAssertion(Annotation( "ChEBI") "aldopentose phosphate") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "aldopentose phosphates") -AnnotationAssertion( "CHEBI:25900") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "aldopentose phosphate") -SubClassOf( ) -SubClassOf( ) - -# Class: (pentose) - -AnnotationAssertion( "A five-carbon monosaccharide which in its linear form contains either an aldehyde group at position 1 (aldopentose) or a ketone group at position 2 (ketopentose).") -AnnotationAssertion(Annotation( "ChEBI") "pentose") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "pentoses") -AnnotationAssertion( "CHEBI:25901") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "pentose") -SubClassOf( ) - # Class: (peptide hormone) AnnotationAssertion( "Any peptide with hormonal activity in animals, whether endocrine, neuroendocrine, or paracrine.") @@ -21402,28 +10434,6 @@ AnnotationAssertion( "biological pigment") SubClassOf( ) -# Class: (polar amino acid) - -AnnotationAssertion( "Any amino acid whose side chain is capable of forming one or more hydrogen bonds.") -AnnotationAssertion( "0") -AnnotationAssertion( "C2H4NO2R") -AnnotationAssertion( "74.059") -AnnotationAssertion( "74.02420") -AnnotationAssertion( "OC(C(*)N)=O") -AnnotationAssertion( "CHEBI:8283") -AnnotationAssertion( "MetaCyc:Polar-amino-acids") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:12016058") -AnnotationAssertion(Annotation( "ChEBI") "polar amino acid") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "polar amino acids") -AnnotationAssertion(Annotation( "ChEBI") "polar amino-acid") -AnnotationAssertion(Annotation( "ChEBI") "polar amino-acids") -AnnotationAssertion( "CHEBI:26167") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "polar amino acid") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (porphyrins) AnnotationAssertion( "Natural pigments containing a fundamental skeleton of four pyrrole nuclei united through the alpha-positions by four methine groups to form a macrocyclic structure.") @@ -21436,127 +10446,6 @@ AnnotationAssertion(rdfs:label "por SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (purine nucleobase) - -AnnotationAssertion( "A nucleobase whose skeleton is derived from purine.") -AnnotationAssertion( "0") -AnnotationAssertion( "C5H3N4R2") -AnnotationAssertion( "119.104") -AnnotationAssertion( "119.03577") -AnnotationAssertion( "C1(NC(=NC=2NC=NC12)*)=*") -AnnotationAssertion( "KEGG:C15587") -AnnotationAssertion(Annotation( "ChEBI") "purine nucleobase") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "UniProt") "a purine nucleobase") -AnnotationAssertion(Annotation( "ChEBI") "purine bases") -AnnotationAssertion(Annotation( "ChEBI") "purine nucleobases") -AnnotationAssertion( "CHEBI:26386") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "purine nucleobase") -SubClassOf( ) -SubClassOf( ) - -# Class: (purine nucleoside diphosphate) - -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "purine nucleoside diphosphates") -AnnotationAssertion( "CHEBI:26391") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "purine nucleoside diphosphate") -SubClassOf( ) - -# Class: (purine nucleoside triphosphate) - -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "purine nucleoside triphosphates") -AnnotationAssertion( "CHEBI:26393") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "purine nucleoside triphosphate") -SubClassOf( ) - -# Class: (purine nucleoside) - -AnnotationAssertion(Annotation( "ChEBI") "purine nucleoside") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "purine nucleosides") -AnnotationAssertion( "CHEBI:26394") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "purine nucleoside") -SubClassOf( ) -SubClassOf( ) - -# Class: (purine nucleotide) - -AnnotationAssertion( "Any nucleotide that has a purine nucleobase.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "purine nucleotides") -AnnotationAssertion( "CHEBI:26395") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "purine nucleotide") -SubClassOf( ) -SubClassOf( ) - -# Class: (purine ribonucleoside diphosphate) - -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "purine ribonucleoside diphosphates") -AnnotationAssertion( "CHEBI:26396") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "purine ribonucleoside diphosphate") -SubClassOf( ) -SubClassOf( ) - -# Class: (purine ribonucleoside triphosphate) - -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "purine ribonucleoside triphosphates") -AnnotationAssertion( "CHEBI:26398") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "purine ribonucleoside triphosphate") -SubClassOf( ) -SubClassOf( ) - -# Class: (purine ribonucleoside) - -AnnotationAssertion( "A ribonucleoside that has a purine moiety as the nucleobase (the R group in the illustration).") -AnnotationAssertion( "0") -AnnotationAssertion( "C5H9O4R") -AnnotationAssertion( "133.123") -AnnotationAssertion( "133.05008") -AnnotationAssertion( "*[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "purine ribonucleosides") -AnnotationAssertion( "CHEBI:26399") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "purine ribonucleoside") -SubClassOf( ) -SubClassOf( ) - -# Class: (purine ribonucleotide) - -AnnotationAssertion( "Any ribonucleotide that has a purine nucleobase.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "purine ribonucleotides") -AnnotationAssertion( "CHEBI:26400") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "purine ribonucleotide") -SubClassOf( ) -SubClassOf( ) - -# Class: (purines) - -AnnotationAssertion( "A class of imidazopyrimidines that consists of purine and its substituted derivatives.") -AnnotationAssertion( "0") -AnnotationAssertion( "C5N4R7") -AnnotationAssertion( "116.080") -AnnotationAssertion( "116.01230") -AnnotationAssertion( "CHEBI:13678") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion( "CHEBI:26401") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "purines") -SubClassOf( ) - # Class: (quaternary nitrogen compound) AnnotationAssertion( "A nitrogen molecular entity that is electronically neutral but which contains a quaternary nitrogen.") @@ -21567,42 +10456,6 @@ AnnotationAssertion(rdfs:label "qua SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (ribonucleotide) - -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "ribonucleotides") -AnnotationAssertion( "CHEBI:26561") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "ribonucleotide") -SubClassOf( ) -SubClassOf( ) - -# Class: (ribose phosphate) - -AnnotationAssertion(Annotation( "ChEBI") "ribose phosphate") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "ribose phosphates") -AnnotationAssertion( "CHEBI:26562") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "ribose phosphate") -SubClassOf( ) - -# Class: (saturated fatty acid) - -AnnotationAssertion( "Any fatty acid containing no carbon to carbon multiple bonds. Known to produce adverse biological effects when ingested to excess.") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:16492686") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:19763019") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:20237329") -AnnotationAssertion(Annotation( "ChEBI") "saturated fatty acid") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "SFA") -AnnotationAssertion(Annotation( "ChEBI") "SFAs") -AnnotationAssertion(Annotation( "ChEBI") "saturated fatty acids") -AnnotationAssertion( "CHEBI:26607") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "saturated fatty acid") -SubClassOf( ) - # Class: (sesquiterpenoid) AnnotationAssertion( "Any terpenoid derived from a sesquiterpene. The term includes compounds in which the C15 skeleton of the parent sesquiterpene has been rearranged or modified by the removal of one or more skeletal atoms (generally methyl groups).") @@ -21616,28 +10469,6 @@ AnnotationAssertion(rdfs:label "ses SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (short-chain fatty acid) - -AnnotationAssertion( "An aliphatic monocarboxylic acid with a chain length of less than C6. If any non-hydrocarbon substituent is present, the compound is not normally regarded as a short-chain fatty acid.") -AnnotationAssertion( "0") -AnnotationAssertion( "CH2OR") -AnnotationAssertion( "45.017") -AnnotationAssertion( "44.99765") -AnnotationAssertion( "OC([*])=O") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:16633129") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:16870803") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:18203540") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:20148677") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "SCFA") -AnnotationAssertion(Annotation( "ChEBI") "SCFAs") -AnnotationAssertion(Annotation( "ChEBI") "short-chain fatty acids") -AnnotationAssertion( "CHEBI:26666") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "short-chain fatty acid") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (sodium atom) AnnotationAssertion( "0") @@ -21703,34 +10534,6 @@ SubClassOf( ) SubClassOf( ) -# Class: (steroid hormone) - -AnnotationAssertion( "Any steroid that acts as hormone.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "Steroidhormon") -AnnotationAssertion(Annotation( "ChEBI") "Steroidhormone") -AnnotationAssertion(Annotation( "ChEBI") "hormona esteroide") -AnnotationAssertion(Annotation( "ChEBI") "hormonas esteroideas") -AnnotationAssertion(Annotation( "ChEBI") "hormone steroide") -AnnotationAssertion(Annotation( "ChEBI") "hormones steroides") -AnnotationAssertion(Annotation( "ChEBI") "steroid hormones") -AnnotationAssertion( "CHEBI:26764") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "steroid hormone") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (carbohydrate phosphate) - -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "carbohydrate phosphates") -AnnotationAssertion( "CHEBI:26816") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "carbohydrate phosphate") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - # Class: (sulfuric ester) AnnotationAssertion( "An ester of an alcohol and sulfuric acid.") @@ -21877,16 +10680,6 @@ AnnotationAssertion(rdfs:label "ter SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (oxolanes) - -AnnotationAssertion( "Any oxacycle having an oxolane (tetrahydrofuran) skeleton.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion( "CHEBI:26912") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "oxolanes") -SubClassOf( ) -SubClassOf( ) - # Class: (tetrapyrrole) AnnotationAssertion( "A natural pigment containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next.") @@ -21914,58 +10707,6 @@ AnnotationAssertion(rdfs:label "tet SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (micronutrient) - -AnnotationAssertion( "Any nutrient required in small quantities by organisms throughout their life in order to orchestrate a range of physiological functions.") -AnnotationAssertion( "Wikipedia:Micronutrient") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "micronutrients") -AnnotationAssertion(Annotation( "ChEBI") "trace elements") -AnnotationAssertion( "CHEBI:27027") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "micronutrient") -SubClassOf( ) - -# Class: (transition element atom) - -AnnotationAssertion( "An element whose atom has an incomplete d sub-shell, or which can give rise to cations with an incomplete d sub-shell.") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "transition element") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "Uebergangselement") -AnnotationAssertion(Annotation( "ChEBI") "Uebergangsmetalle") -AnnotationAssertion(Annotation( "ChEBI") "metal de transicion") -AnnotationAssertion(Annotation( "ChEBI") "metal de transition") -AnnotationAssertion(Annotation( "ChEBI") "metales de transicion") -AnnotationAssertion(Annotation( "ChEBI") "metaux de transition") -AnnotationAssertion(Annotation( "ChEBI") "transition element") -AnnotationAssertion(Annotation( "ChEBI") "transition elements") -AnnotationAssertion(Annotation( "ChEBI") "transition metal") -AnnotationAssertion(Annotation( "ChEBI") "transition metals") -AnnotationAssertion( "CHEBI:27081") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "transition element atom") -SubClassOf( ) - -# Class: (tryptamines) - -AnnotationAssertion( "Tryptamine and its substitution derivatives.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion( "CHEBI:27162") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "tryptamines") -SubClassOf( ) - -# Class: (organic heterobicyclic compound) - -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "heterobicyclic compounds") -AnnotationAssertion(Annotation( "ChEBI") "organic heterobicyclic compounds") -AnnotationAssertion( "CHEBI:27171") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "organic heterobicyclic compound") -SubClassOf( ) -SubClassOf( ) - # Class: (univalent carboacyl group) AnnotationAssertion( "A univalent carboacyl group is a group formed by loss of OH from the carboxy group of a carboxylic acid.") @@ -22041,57 +10782,6 @@ SubClassOf( ObjectSomeValuesFrom( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (aldosterone) - -AnnotationAssertion( "A pregnane-based steroidal hormone produced by the outer-section (zona glomerulosa) of the adrenal cortex in the adrenal gland, and acts on the distal tubules and collecting ducts of the kidney to cause the conservation of sodium, secretion of potassium, increased water retention, and increased blood pressure. The overall effect of aldosterone is to increase reabsorption of ions and water in the kidney.") -AnnotationAssertion( "0") -AnnotationAssertion( "C21H28O5") -AnnotationAssertion( "InChI=1S/C21H28O5/c1-20-7-6-13(24)8-12(20)2-3-14-15-4-5-16(18(26)10-22)21(15,11-23)9-17(25)19(14)20/h8,11,14-17,19,22,25H,2-7,9-10H2,1H3/t14-,15-,16+,17-,19+,20-,21+/m0/s1") -AnnotationAssertion( "PQSUYGKTWSAVDQ-ZVIOFETBSA-N") -AnnotationAssertion( "360.44400") -AnnotationAssertion( "360.19367") -AnnotationAssertion( "[H][C@@]1(CC[C@@]2([H])[C@]3([H])CCC4=CC(=O)CC[C@]4(C)[C@@]3([H])[C@@H](O)C[C@]12C=O)C(=O)CO") -AnnotationAssertion( "CHEBI:22306") -AnnotationAssertion( "CHEBI:2563") -AnnotationAssertion( "CHEBI:40919") -AnnotationAssertion(Annotation( "ChemIDplus") "Beilstein:3224996") -AnnotationAssertion(Annotation( "ChemIDplus") "CAS:52-39-1") -AnnotationAssertion(Annotation( "KEGG COMPOUND") "CAS:52-39-1") -AnnotationAssertion(Annotation( "NIST Chemistry WebBook") "CAS:52-39-1") -AnnotationAssertion( "DrugBank:DB04630") -AnnotationAssertion(Annotation( "DrugCentral") "Drug_Central:111") -AnnotationAssertion( "HMDB:HMDB0000037") -AnnotationAssertion( "KEGG:C01780") -AnnotationAssertion( "LINCS:LSM-42770") -AnnotationAssertion(Annotation( "LIPID MAPS") "LIPID_MAPS_instance:LMST02030026") -AnnotationAssertion( "PDBeChem:AS4") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:10438974") -AnnotationAssertion(Annotation( "Reaxys") "Reaxys:3224996") -AnnotationAssertion( "Wikipedia:Aldosterone") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "11beta,21-dihydroxy-3,20-dioxopregn-4-en-18-al") -AnnotationAssertion(Annotation( "PDBeChem") "ALDOSTERONE") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Aldosterone") -AnnotationAssertion(Annotation( "UniProt") "aldosterone") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "NIST_Chemistry_WebBook") "(+)-aldosterone") -AnnotationAssertion(Annotation( "NIST_Chemistry_WebBook") "(11beta)-11,21-dihydroxy-3,20-dioxopregn-4-en-18-al") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "11beta,21-Dihydroxy-3,20-dioxo-4-pregnen-18-al") -AnnotationAssertion( "CHEBI:27584") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "aldosterone") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (carbon atom) AnnotationAssertion( "0") @@ -22125,31 +10815,6 @@ SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (glycogen) - -AnnotationAssertion( "A polydisperse, highly branched glucan composed of chains of D-glucopyranose residues in alpha(1->4) glycosidic linkage, joined together by alpha(1->6) glycosidic linkages. A small number of alpha(1->3) glycosidic linkages and some cumulative alpha(1->6) links also may occur. The branches in glycogen typically contain 8 to 12 glucose residues.") -AnnotationAssertion( "CHEBI:24379") -AnnotationAssertion( "CHEBI:5466") -AnnotationAssertion(Annotation( "ChemIDplus") "CAS:9005-79-2") -AnnotationAssertion(Annotation( "KEGG COMPOUND") "CAS:9005-79-2") -AnnotationAssertion( "GlyGen:G99991IU") -AnnotationAssertion( "GlyTouCan:G99991IU") -AnnotationAssertion( "HMDB:HMDB0000757") -AnnotationAssertion( "KEGG:C00182") -AnnotationAssertion( "MetaCyc:CPD0-971") -AnnotationAssertion( "Wikipedia:Glycogen") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Glycogen") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "GlyTouCan") "WURCS=2.0/1,4,3/[a2122h-1a_1-5]/1-1-1-1/a4-b1_b4-c1_b6-d1") -AnnotationAssertion(Annotation( "ChemIDplus") "animal starch") -AnnotationAssertion(Annotation( "ChemIDplus") "liver starch") -AnnotationAssertion( "CHEBI:28087") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "glycogen") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (alpha-carotene) AnnotationAssertion( "A cyclic carotene with a beta- and an epsilon-ring at opposite ends respectively.") @@ -22258,59 +10923,6 @@ SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (serotonin) - -AnnotationAssertion( "A primary amino compound that is the 5-hydroxy derivative of tryptamine.") -AnnotationAssertion( "0") -AnnotationAssertion( "C10H12N2O") -AnnotationAssertion( "InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2") -AnnotationAssertion( "QZAYGJVTTNCVMB-UHFFFAOYSA-N") -AnnotationAssertion( "176.215") -AnnotationAssertion( "176.09496") -AnnotationAssertion( "C1=CC(=CC=2C(=CNC12)CCN)O") -AnnotationAssertion( "CHEBI:1420") -AnnotationAssertion( "CHEBI:26652") -AnnotationAssertion( "CHEBI:49894") -AnnotationAssertion(Annotation( "Beilstein") "Beilstein:143524") -AnnotationAssertion(Annotation( "ChemIDplus") "CAS:50-67-9") -AnnotationAssertion(Annotation( "KEGG COMPOUND") "CAS:50-67-9") -AnnotationAssertion(Annotation( "Gmelin") "Gmelin:1861995") -AnnotationAssertion( "HMDB:HMDB0000259") -AnnotationAssertion( "KEGG:C00780") -AnnotationAssertion( "KNApSAcK:C00001429") -AnnotationAssertion( "LINCS:LSM-6589") -AnnotationAssertion( "MetaCyc:SEROTONIN") -AnnotationAssertion( "PDBeChem:SRO") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:18593914") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:22770225") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:24136337") -AnnotationAssertion(Annotation( "Reaxys") "Reaxys:143524") -AnnotationAssertion( "Wikipedia:Serotonin") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "3-(2-aminoethyl)-1H-indol-5-ol") -AnnotationAssertion(Annotation( "PDBeChem") "SEROTONIN") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Serotonin") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "3-(2-Aminoethyl)-1H-indol-5-ol") -AnnotationAssertion(Annotation( "IUPHAR") "5-HT") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "5-Hydroxytryptamine") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Enteramine") -AnnotationAssertion(Annotation( "ChEBI") "serotonine") -AnnotationAssertion(Annotation( "ChemIDplus") "thrombocytin") -AnnotationAssertion(Annotation( "ChemIDplus") "thrombotonin") -AnnotationAssertion( "CHEBI:28790") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "serotonin") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (lutein) AnnotationAssertion( "0") @@ -22356,122 +10968,6 @@ SubClassOf( ObjectSomeValuesFrom( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (fatty acid anion) - -AnnotationAssertion( "The conjugate base of a fatty acid, arising from deprotonation of the carboxylic acid group of the corresponding fatty acid.") -AnnotationAssertion( "-1") -AnnotationAssertion( "CO2R") -AnnotationAssertion( "44.00950") -AnnotationAssertion( "43.98983") -AnnotationAssertion( "[O-]C([*])=O") -AnnotationAssertion( "CHEBI:13634") -AnnotationAssertion( "CHEBI:24022") -AnnotationAssertion( "CHEBI:4985") -AnnotationAssertion( "KEGG:C02403") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:18628202") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Fatty acid anion") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Alkanate") -AnnotationAssertion(Annotation( "ChEBI") "Fettsaeureanion") -AnnotationAssertion(Annotation( "ChEBI") "Fettsaeureanionen") -AnnotationAssertion(Annotation( "UniProt") "a fatty acid") -AnnotationAssertion(Annotation( "ChEBI") "acido graso anionico") -AnnotationAssertion(Annotation( "ChEBI") "acidos grasos anionicos") -AnnotationAssertion(Annotation( "ChEBI") "anion de l'acide gras") -AnnotationAssertion(Annotation( "ChEBI") "fatty acid anions") -AnnotationAssertion( "CHEBI:28868") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "fatty acid anion") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: ((R)-adrenaline) - -AnnotationAssertion( "The R-enantiomer of adrenaline. It is a hormone secreted by the adrenal glands resulting in the 'fight-or-flight' response.") -AnnotationAssertion( "0") -AnnotationAssertion( "C9H13NO3") -AnnotationAssertion( "InChI=1S/C9H13NO3/c1-10-5-9(13)6-2-3-7(11)8(12)4-6/h2-4,9-13H,5H2,1H3/t9-/m0/s1") -AnnotationAssertion( "UCTWMZQNUQWSLP-VIFPVBQESA-N") -AnnotationAssertion( "183.20440") -AnnotationAssertion( "183.08954") -AnnotationAssertion( "CNC[C@H](O)c1ccc(O)c(O)c1") -AnnotationAssertion( "CHEBI:1942") -AnnotationAssertion( "CHEBI:23928") -AnnotationAssertion(Annotation( "Beilstein") "Beilstein:2368277") -AnnotationAssertion(Annotation( "ChemIDplus") "CAS:51-43-4") -AnnotationAssertion(Annotation( "KEGG COMPOUND") "CAS:51-43-4") -AnnotationAssertion(Annotation( "NIST Chemistry WebBook") "CAS:51-43-4") -AnnotationAssertion( "DrugBank:DB00668") -AnnotationAssertion(Annotation( "DrugCentral") "Drug_Central:1028") -AnnotationAssertion( "HMDB:HMDB0000068") -AnnotationAssertion( "KEGG:C00788") -AnnotationAssertion( "KEGG:D00095") -AnnotationAssertion( "KNApSAcK:C00029643") -AnnotationAssertion( "MetaCyc:L-EPINEPHRINE") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:18325983") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:21963816") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:22115931") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:22405854") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:22425731") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:22429969") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:22569014") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:22623754") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:22826982") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:22895980") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:22898765") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:22905594") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:22940899") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:23066296") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:23130169") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:23164182") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:23185846") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:29438107") -AnnotationAssertion(Annotation( "Reaxys") "Reaxys:2368277") -AnnotationAssertion( "Wikipedia:Epinephrine") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "4-[(1R)-1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChemIDplus") "(-)-(R)-epinephrine") -AnnotationAssertion(Annotation( "NIST_Chemistry_WebBook") "(-)-3,4-dihydroxy-alpha-((methylamino)methyl)benzyl alcohol") -AnnotationAssertion(Annotation( "IUPHAR") "(-)-adrenaline") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "(R)-(-)-Adnephrine") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "(R)-(-)-Adrenaline") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "(R)-(-)-Epinephrine") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "(R)-(-)-Epirenamine") -AnnotationAssertion(Annotation( "ChEBI") "(R)-(-)-adrenaline") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol") -AnnotationAssertion(Annotation( "KEGG_DRUG") Annotation( ) "Adrenalin") -AnnotationAssertion(Annotation( "NIST_Chemistry_WebBook") "Adrenalin") -AnnotationAssertion(Annotation( "ChEBI") "Epinephrin") -AnnotationAssertion(Annotation( "DrugBank") Annotation( ) "Epipen") -AnnotationAssertion(Annotation( "KEGG_DRUG") Annotation( ) "Epipen") -AnnotationAssertion(Annotation( "DrugBank") Annotation( ) "Epipen JR") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "L-Adrenaline") -AnnotationAssertion(Annotation( "DrugBank") Annotation( ) "Primatene") -AnnotationAssertion(Annotation( "ChEBI") "adrenaline") -AnnotationAssertion(Annotation( "NIST_Chemistry_WebBook") "adrenaline") -AnnotationAssertion(Annotation( "ChemIDplus") Annotation( ) "epinefrina") -AnnotationAssertion(Annotation( "ChEBI") Annotation( ) "epinephrine") -AnnotationAssertion(Annotation( "ChemIDplus") Annotation( ) "epinephrine") -AnnotationAssertion(Annotation( "ChemIDplus") Annotation( ) "epinephrinum") -AnnotationAssertion(Annotation( "IUPHAR") "levoepinephrine") -AnnotationAssertion( "CHEBI:28918") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "(R)-adrenaline") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (ammonium) AnnotationAssertion( "An onium cation obtained by protonation of ammonia.") @@ -22645,24 +11141,6 @@ SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (mononucleotide) - -AnnotationAssertion( "0") -AnnotationAssertion( "C5H10O7PR") -AnnotationAssertion( "213.103") -AnnotationAssertion( "213.01641") -AnnotationAssertion( "CHEBI:14616") -AnnotationAssertion( "CHEBI:25404") -AnnotationAssertion( "CHEBI:6983") -AnnotationAssertion( "KEGG:C02171") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Mononucleotide") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "mononucleotides") -AnnotationAssertion( "CHEBI:29075") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "mononucleotide") -SubClassOf( ) - # Class: (sodium(1+)) AnnotationAssertion( "A monoatomic monocation obtained from sodium.") @@ -22779,261 +11257,6 @@ SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (oxonium) - -AnnotationAssertion( "+1") -AnnotationAssertion( "H3O") -AnnotationAssertion( "InChI=1S/H2O/h1H2/p+1") -AnnotationAssertion( "XLYOFNOQVPJJNP-UHFFFAOYSA-O") -AnnotationAssertion( "19.02322") -AnnotationAssertion( "19.01784") -AnnotationAssertion( "[H][O+]([H])[H]") -AnnotationAssertion(Annotation( "ChemIDplus") "CAS:13968-08-6") -AnnotationAssertion(Annotation( "NIST Chemistry WebBook") "CAS:13968-08-6") -AnnotationAssertion(Annotation( "Gmelin") "Gmelin:141") -AnnotationAssertion( "MolBase:1646") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "aquahydrogen(1+)") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "oxidanium") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "oxonium") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "trihydridooxygen(1+)") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "IUPAC") "H3O(+)") -AnnotationAssertion(Annotation( "NIST_Chemistry_WebBook") "Hydronium cation") -AnnotationAssertion(Annotation( "ChemIDplus") "Hydronium ion") -AnnotationAssertion(Annotation( "MolBase") "[OH3](+)") -AnnotationAssertion( "CHEBI:29412") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "oxonium") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (hydridodioxygen(1+)) - -AnnotationAssertion( "+1") -AnnotationAssertion( "HO2") -AnnotationAssertion( "InChI=1S/O2/c1-2/p+1") -AnnotationAssertion( "MYMOFIZGZYHOMD-UHFFFAOYSA-O") -AnnotationAssertion( "33.00674") -AnnotationAssertion( "32.99711") -AnnotationAssertion( "[H][O+]=O") -AnnotationAssertion(Annotation( "Gmelin") "Gmelin:508") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "dioxidenium") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "hydridodioxygen(1+)") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "IUPAC") "HO2(+)") -AnnotationAssertion(Annotation( "ChEBI") "HOO(+)") -AnnotationAssertion(Annotation( "ChEBI") "[HO2](+)") -AnnotationAssertion( "CHEBI:29793") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "hydridodioxygen(1+)") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (L-glutamate(1-)) - -AnnotationAssertion( "An alpha-amino-acid anion that is the conjugate base of L-glutamic acid, having anionic carboxy groups and a cationic amino group") -AnnotationAssertion( "-1") -AnnotationAssertion( "C5H8NO4") -AnnotationAssertion( "InChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/p-1/t3-/m0/s1") -AnnotationAssertion( "WHUUTDBJXJRKMK-VKHMYHEASA-M") -AnnotationAssertion( "146.12136") -AnnotationAssertion( "146.04588") -AnnotationAssertion( "[NH3+][C@@H](CCC([O-])=O)C([O-])=O") -AnnotationAssertion( "CHEBI:13107") -AnnotationAssertion( "CHEBI:21301") -AnnotationAssertion(Annotation( "ChemIDplus") "CAS:11070-68-1") -AnnotationAssertion(Annotation( "Gmelin") "Gmelin:936654") -AnnotationAssertion( "MetaCyc:GLT") -AnnotationAssertion(Annotation( "JCBN") "L-glutamate(1-)") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "hydrogen L-glutamate") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "IUPAC") "(2S)-2-ammoniopentanedioate") -AnnotationAssertion(Annotation( "ChEBI") "L-glutamate") -AnnotationAssertion(Annotation( "UniProt") "L-glutamate") -AnnotationAssertion(Annotation( "JCBN") "L-glutamic acid monoanion") -AnnotationAssertion(Annotation( "ChemIDplus") "L-glutamic acid, ion(1-)") -AnnotationAssertion( "CHEBI:29985") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "L-glutamate(1-)") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (D-glutamate(1-)) - -AnnotationAssertion( "An alpha-amino-acid anion that is the conjugate base of D-glutamic acid, having anionic carboxy groups and a cationic amino group") -AnnotationAssertion( "-1") -AnnotationAssertion( "C5H8NO4") -AnnotationAssertion( "InChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/p-1/t3-/m1/s1") -AnnotationAssertion( "WHUUTDBJXJRKMK-GSVOUGTGSA-M") -AnnotationAssertion( "146.12136") -AnnotationAssertion( "146.04588") -AnnotationAssertion( "[NH3+][C@H](CCC([O-])=O)C([O-])=O") -AnnotationAssertion( "CHEBI:12979") -AnnotationAssertion( "CHEBI:21022") -AnnotationAssertion(Annotation( "Beilstein") "Beilstein:8319427") -AnnotationAssertion( "MetaCyc:D-GLT") -AnnotationAssertion(Annotation( "JCBN") "D-glutamate(1-)") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "hydrogen D-glutamate") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "IUPAC") "(2R)-2-ammoniopentanedioate") -AnnotationAssertion(Annotation( "UniProt") "D-glutamate") -AnnotationAssertion(Annotation( "JCBN") "D-glutamic acid monoanion") -AnnotationAssertion( "CHEBI:29986") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "D-glutamate(1-)") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (glutamate(2-)) - -AnnotationAssertion( "A dicarboxylic acid dianion that is the conjugate base of glutamate(1-).") -AnnotationAssertion( "-2") -AnnotationAssertion( "C5H7NO4") -AnnotationAssertion( "InChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/p-2") -AnnotationAssertion( "WHUUTDBJXJRKMK-UHFFFAOYSA-L") -AnnotationAssertion( "145.11342") -AnnotationAssertion( "145.03860") -AnnotationAssertion( "NC(CCC([O-])=O)C([O-])=O") -AnnotationAssertion(Annotation( "Beilstein") "Beilstein:4134100") -AnnotationAssertion(Annotation( "Gmelin") "Gmelin:327903") -AnnotationAssertion(Annotation( "Reaxys") "Reaxys:4134100") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "2-aminopentanedioate") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "glutamate") -AnnotationAssertion(Annotation( "JCBN") "glutamate(2-)") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "JCBN") "glutamic acid dianion") -AnnotationAssertion( "CHEBI:29987") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "glutamate(2-)") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (L-glutamate(2-)) - -AnnotationAssertion( "An L-alpha-amino acid anion that is the dianion obtained by the deprotonation of the both the carboxy groups of L-glutamic acid.") -AnnotationAssertion( "-2") -AnnotationAssertion( "C5H7NO4") -AnnotationAssertion( "InChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/p-2/t3-/m0/s1") -AnnotationAssertion( "WHUUTDBJXJRKMK-VKHMYHEASA-L") -AnnotationAssertion( "145.11342") -AnnotationAssertion( "145.03860") -AnnotationAssertion( "N[C@@H](CCC([O-])=O)C([O-])=O") -AnnotationAssertion(Annotation( "Gmelin") "Gmelin:327905") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "(2S)-2-aminopentanedioate") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "L-glutamate") -AnnotationAssertion(Annotation( "JCBN") "L-glutamate(2-)") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "JCBN") "L-glutamic acid dianion") -AnnotationAssertion( "CHEBI:29988") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "L-glutamate(2-)") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (D-glutamate(2-)) - -AnnotationAssertion( "-2") -AnnotationAssertion( "C5H7NO4") -AnnotationAssertion( "InChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/p-2/t3-/m1/s1") -AnnotationAssertion( "WHUUTDBJXJRKMK-GSVOUGTGSA-L") -AnnotationAssertion( "145.11342") -AnnotationAssertion( "145.03860") -AnnotationAssertion( "N[C@H](CCC([O-])=O)C([O-])=O") -AnnotationAssertion(Annotation( "Beilstein") "Beilstein:8143000") -AnnotationAssertion(Annotation( "Gmelin") "Gmelin:327904") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "(2R)-2-aminopentanedioate") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "D-glutamate") -AnnotationAssertion(Annotation( "JCBN") "D-glutamate(2-)") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "JCBN") "D-glutamic acid dianion") -AnnotationAssertion( "CHEBI:29989") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "D-glutamate(2-)") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (acetate) - -AnnotationAssertion( "A monocarboxylic acid anion resulting from the removal of a proton from the carboxy group of acetic acid.") -AnnotationAssertion( "-1") -AnnotationAssertion( "C2H3O2") -AnnotationAssertion( "InChI=1S/C2H4O2/c1-2(3)4/h1H3,(H,3,4)/p-1") -AnnotationAssertion( "QTBSBXVTEAMEQO-UHFFFAOYSA-M") -AnnotationAssertion( "59.04402") -AnnotationAssertion( "59.01385") -AnnotationAssertion( "CC([O-])=O") -AnnotationAssertion( "CHEBI:13704") -AnnotationAssertion( "CHEBI:22165") -AnnotationAssertion( "CHEBI:40480") -AnnotationAssertion(Annotation( "Beilstein") "Beilstein:1901470") -AnnotationAssertion(Annotation( "ChemIDplus") "CAS:71-50-1") -AnnotationAssertion(Annotation( "NIST Chemistry WebBook") "CAS:71-50-1") -AnnotationAssertion( "DrugBank:DB03166") -AnnotationAssertion(Annotation( "Gmelin") "Gmelin:1379") -AnnotationAssertion( "KEGG:C00033") -AnnotationAssertion( "MetaCyc:ACET") -AnnotationAssertion( "PDBeChem:ACT") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:17190852") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:22211106") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:22371380") -AnnotationAssertion(Annotation( "Reaxys") "Reaxys:1901470") -AnnotationAssertion(Annotation( "UM-BBD") "UM-BBD_compID:c0050") -AnnotationAssertion( "Wikipedia:Acetate") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "acetate") -AnnotationAssertion(Annotation( "UniProt") "acetate") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "PDBeChem") "ACETATE ION") -AnnotationAssertion(Annotation( "ChEBI") "Azetat") -AnnotationAssertion(Annotation( "IUPAC") "CH3-COO(-)") -AnnotationAssertion(Annotation( "ChEBI") "Ethanoat") -AnnotationAssertion(Annotation( "NIST_Chemistry_WebBook") "MeCO2 anion") -AnnotationAssertion(Annotation( "ChemIDplus") "acetic acid, ion(1-)") -AnnotationAssertion(Annotation( "ChEBI") "ethanoate") -AnnotationAssertion( "CHEBI:30089") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "acetate") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (photon) - -AnnotationAssertion( "Particle of zero charge, zero rest mass, spin quantum number 1, energy hnu and momentum hnu/c (h is the Planck constant, nu the frequency of radiation and c the speed of light), carrier of electromagnetic force.") -AnnotationAssertion( "0") -AnnotationAssertion( "0.0") -AnnotationAssertion( "0.0") -AnnotationAssertion( "*") -AnnotationAssertion( "CHEBI:10581") -AnnotationAssertion( "CHEBI:14383") -AnnotationAssertion( "KEGG:C00205") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "photon") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "Lichtquant") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Light") -AnnotationAssertion(Annotation( "ChEBI") "foton") -AnnotationAssertion(Annotation( "IUPAC") "gamma") -AnnotationAssertion(Annotation( "IUPAC") "hnu") -AnnotationAssertion(Annotation( "UniProt") "hnu") -AnnotationAssertion(Annotation( "ChEBI") "light quantum") -AnnotationAssertion( "CHEBI:30212") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "photon") -SubClassOf( ) - # Class: (monoatomic dication) AnnotationAssertion( "+2") @@ -23051,280 +11274,6 @@ AnnotationAssertion( "monoatomic dication") SubClassOf( ) -# Class: (gamma-aminobutyrate) - -AnnotationAssertion( "An gamma-amino acid anion resulting from the deprotonation of the carboxy group of gamma-aminobutyric acid.") -AnnotationAssertion( "-1") -AnnotationAssertion( "C4H8NO2") -AnnotationAssertion( "InChI=1S/C4H9NO2/c5-3-1-2-4(6)7/h1-3,5H2,(H,6,7)/p-1") -AnnotationAssertion( "BTCSSZJGUNDROE-UHFFFAOYSA-M") -AnnotationAssertion( "102.11186") -AnnotationAssertion( "102.05605") -AnnotationAssertion( "NCCCC([O-])=O") -AnnotationAssertion( "CHEBI:11961") -AnnotationAssertion( "CHEBI:20317") -AnnotationAssertion(Annotation( "Beilstein") "Beilstein:3536873") -AnnotationAssertion(Annotation( "Gmelin") "Gmelin:559138") -AnnotationAssertion( "KEGG:C00334") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:12509893") -AnnotationAssertion(Annotation( "Reaxys") "Reaxys:3536873") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "4-aminobutanoate") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "4-Amino-butyrat") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "4-Aminobutylate") -AnnotationAssertion(Annotation( "ChEBI") "4-aminobutanoic acid ion (1-)") -AnnotationAssertion(Annotation( "ChEBI") "4-aminobutyrate") -AnnotationAssertion(Annotation( "ChEBI") "gamma-aminobutanoate") -AnnotationAssertion(Annotation( "ChEBI") "gamma-aminobutyrate anion") -AnnotationAssertion( "CHEBI:30566") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "gamma-aminobutyrate") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (ATP(4-)) - -AnnotationAssertion( "A nucleoside triphosphate(4-) obtained by global deprotonation of the triphosphate OH groups of ATP; major species present at pH 7.3.") -AnnotationAssertion( "-4") -AnnotationAssertion( "C10H12N5O13P3") -AnnotationAssertion( "InChI=1S/C10H16N5O13P3/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20)/p-4/t4-,6-,7-,10-/m1/s1") -AnnotationAssertion( "ZKHQWZAMYRWXGA-KQYNXXCUSA-J") -AnnotationAssertion( "503.14946") -AnnotationAssertion( "502.96664") -AnnotationAssertion( "Nc1ncnc2n(cnc12)[C@@H]1O[C@H](COP([O-])(=O)OP([O-])(=O)OP([O-])([O-])=O)[C@@H](O)[C@H]1O") -AnnotationAssertion(Annotation( "Beilstein") "Beilstein:3581767") -AnnotationAssertion(Annotation( "Gmelin") "Gmelin:342798") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "adenosine 5'-triphosphate(4-)") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "UniProt") "ATP") -AnnotationAssertion(Annotation( "IUPAC") "atp") -AnnotationAssertion( "CHEBI:30616") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "ATP(4-)") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (formic acid) - -AnnotationAssertion( "The simplest carboxylic acid, containing a single carbon. Occurs naturally in various sources including the venom of bee and ant stings, and is a useful organic synthetic reagent. Principally used as a preservative and antibacterial agent in livestock feed. Induces severe metabolic acidosis and ocular injury in human subjects.") -AnnotationAssertion( "0") -AnnotationAssertion( "CH2O2") -AnnotationAssertion( "InChI=1S/CH2O2/c2-1-3/h1H,(H,2,3)") -AnnotationAssertion( "BDAGIHXWWSANSR-UHFFFAOYSA-N") -AnnotationAssertion( "46.02538") -AnnotationAssertion( "46.00548") -AnnotationAssertion( "[H]C(O)=O") -AnnotationAssertion( "CHEBI:24082") -AnnotationAssertion( "CHEBI:42460") -AnnotationAssertion( "CHEBI:5145") -AnnotationAssertion( "BPDB:1749") -AnnotationAssertion(Annotation( "Beilstein") "Beilstein:1209246") -AnnotationAssertion(Annotation( "ChemIDplus") "CAS:64-18-6") -AnnotationAssertion(Annotation( "KEGG COMPOUND") "CAS:64-18-6") -AnnotationAssertion(Annotation( "NIST Chemistry WebBook") "CAS:64-18-6") -AnnotationAssertion( "DrugBank:DB01942") -AnnotationAssertion(Annotation( "Gmelin") "Gmelin:1008") -AnnotationAssertion( "HMDB:HMDB0000142") -AnnotationAssertion( "KEGG:C00058") -AnnotationAssertion( "KNApSAcK:C00001182") -AnnotationAssertion(Annotation( "LIPID MAPS") "LIPID_MAPS_instance:LMFA01010040") -AnnotationAssertion( "MetaCyc:FORMATE") -AnnotationAssertion( "PDBeChem:FMT") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:12591956") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:14637377") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:15811469") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:16120414") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:16185830") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:16222862") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:16230297") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:16445901") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:16465784") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:18034701") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:18397576") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:22080171") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:22280475") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:22304812") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:22385261") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:22447125") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:22483350") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:22499553") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:22540994") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:22606986") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:22622393") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:3946945") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:7361809") -AnnotationAssertion( "Patent:CN101481304") -AnnotationAssertion(Annotation( "Reaxys") "Reaxys:1209246") -AnnotationAssertion( "Wikipedia:Formic_acid") -AnnotationAssertion(Annotation( "PDBeChem") "FORMIC ACID") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Formic acid") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "formic acid") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChemIDplus") "Acide formique") -AnnotationAssertion(Annotation( "ChemIDplus") "Ameisensaeure") -AnnotationAssertion(Annotation( "IUPAC") "H-COOH") -AnnotationAssertion(Annotation( "ChEBI") "HCO2H") -AnnotationAssertion(Annotation( "NIST_Chemistry_WebBook") "HCOOH") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Methanoic acid") -AnnotationAssertion(Annotation( "ChemIDplus") "aminic acid") -AnnotationAssertion(Annotation( "ChemIDplus") "bilorin") -AnnotationAssertion(Annotation( "ChemIDplus") "formylic acid") -AnnotationAssertion(Annotation( "ChemIDplus") "hydrogen carboxylic acid") -AnnotationAssertion(Annotation( "ChEBI") "methoic acid") -AnnotationAssertion( "CHEBI:30751") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "formic acid") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (butyric acid) - -AnnotationAssertion( "A straight-chain saturated fatty acid that is butane in which one of the terminal methyl groups has been oxidised to a carboxy group.") -AnnotationAssertion( "0") -AnnotationAssertion( "C4H8O2") -AnnotationAssertion( "InChI=1S/C4H8O2/c1-2-3-4(5)6/h2-3H2,1H3,(H,5,6)") -AnnotationAssertion( "FERIUCNNQQJTOY-UHFFFAOYSA-N") -AnnotationAssertion( "88.10510") -AnnotationAssertion( "88.05243") -AnnotationAssertion( "CCCC(O)=O") -AnnotationAssertion( "CHEBI:113450") -AnnotationAssertion( "CHEBI:22948") -AnnotationAssertion( "CHEBI:3234") -AnnotationAssertion( "CHEBI:41208") -AnnotationAssertion(Annotation( "Beilstein") "Beilstein:906770") -AnnotationAssertion(Annotation( "ChemIDplus") "CAS:107-92-6") -AnnotationAssertion(Annotation( "KEGG COMPOUND") "CAS:107-92-6") -AnnotationAssertion(Annotation( "NIST Chemistry WebBook") "CAS:107-92-6") -AnnotationAssertion( "DrugBank:DB03568") -AnnotationAssertion(Annotation( "Gmelin") "Gmelin:26242") -AnnotationAssertion( "HMDB:HMDB0000039") -AnnotationAssertion( "KEGG:C00246") -AnnotationAssertion( "KNApSAcK:C00001180") -AnnotationAssertion(Annotation( "LIPID MAPS") "LIPID_MAPS_instance:LMFA01010004") -AnnotationAssertion( "MetaCyc:BUTYRIC_ACID") -AnnotationAssertion( "PDBeChem:BUA") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:10736622") -AnnotationAssertion(Annotation( "ChEMBL") "PMID:10956204") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:11201044") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:11208715") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:11238216") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:11305323") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:12068484") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:13678314") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:14962641") -AnnotationAssertion(Annotation( "ChEMBL") "PMID:1542095") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:15809727") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:15810631") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:15938880") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:19318247") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:19366864") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:19703412") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:21699495") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:22038864") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:22194341") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:22322557") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:22339023") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:22466881") -AnnotationAssertion(Annotation( "Reaxys") "Reaxys:906770") -AnnotationAssertion( "Wikipedia:Butyric_acid") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Butyric acid") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "butanoic acid") -AnnotationAssertion(Annotation( "IUPAC") "butyric acid") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "HMDB") "1-butanoic acid") -AnnotationAssertion(Annotation( "HMDB") "1-butyric acid") -AnnotationAssertion(Annotation( "MetaCyc") "1-propanecarboxylic acid") -AnnotationAssertion(Annotation( "ChEBI") "4:0") -AnnotationAssertion(Annotation( "PDBeChem") "BUTANOIC ACID") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Butanoate") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Butanoic acid") -AnnotationAssertion(Annotation( "ChEBI") "Buttersaeure") -AnnotationAssertion(Annotation( "ChEBI") "C4:0") -AnnotationAssertion(Annotation( "IUPAC") "CH3-[CH2]2-COOH") -AnnotationAssertion(Annotation( "IUPAC") "acide butanoique") -AnnotationAssertion(Annotation( "ChEBI") "acide butyrique") -AnnotationAssertion(Annotation( "ChEBI") "butanic acid") -AnnotationAssertion(Annotation( "ChEBI") "butoic acid") -AnnotationAssertion(Annotation( "NIST_Chemistry_WebBook") "ethylacetic acid") -AnnotationAssertion(Annotation( "NIST_Chemistry_WebBook") "n-butanoic acid") -AnnotationAssertion(Annotation( "NIST_Chemistry_WebBook") "n-butyric acid") -AnnotationAssertion(Annotation( "HMDB") "propanecarboxylic acid") -AnnotationAssertion(Annotation( "MetaCyc") "propylformic acid") -AnnotationAssertion( "CHEBI:30772") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "butyric acid") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (alcohol) - -AnnotationAssertion( "A compound in which a hydroxy group, -OH, is attached to a saturated carbon atom.") -AnnotationAssertion( "0") -AnnotationAssertion( "HOR") -AnnotationAssertion( "17.007") -AnnotationAssertion( "17.00274") -AnnotationAssertion( "O[*]") -AnnotationAssertion( "CHEBI:13804") -AnnotationAssertion( "CHEBI:22288") -AnnotationAssertion( "CHEBI:2553") -AnnotationAssertion( "KEGG:C00069") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Alcohol") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "alcohols") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "UniProt") "an alcohol") -AnnotationAssertion( "CHEBI:30879") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "alcohol") -SubClassOf( ) - -# Class: (bile acid) - -AnnotationAssertion( "Any member of a group of hydroxy-5beta-cholanic acids occuring in bile, where they are present as the sodium salts of their amides with glycine or taurine. In mammals bile acids almost invariably have 5beta-configuration.") -AnnotationAssertion( "KEGG:C01558") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Bile acid") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "5beta-bile acid") -AnnotationAssertion(Annotation( "ChEBI") "5beta-bile acids") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Bile salt") -AnnotationAssertion(Annotation( "ChEBI") "Gallensaeure") -AnnotationAssertion(Annotation( "ChEBI") "Gallensaeuren") -AnnotationAssertion(Annotation( "ChEBI") "bile acids") -AnnotationAssertion( "CHEBI:3098") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "bile acid") -SubClassOf( ) -SubClassOf( ) - -# Class: (amine) - -AnnotationAssertion( "A compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups.") -AnnotationAssertion( "CHEBI:13814") -AnnotationAssertion( "CHEBI:22474") -AnnotationAssertion( "CHEBI:2641") -AnnotationAssertion( "KEGG:C00706") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Amine") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "amines") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "Amin") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Substituted amine") -AnnotationAssertion( "CHEBI:32952") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "amine") -SubClassOf( ) - # Class: (amide) AnnotationAssertion( "An amide is a derivative of an oxoacid RkE(=O)l(OH)m (l =/= 0) in which an acidic hydroxy group has been replaced by an amino or substituted amino group.") @@ -23543,23 +11492,6 @@ SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (monoatomic hydrogen) - -AnnotationAssertion( "0") -AnnotationAssertion( "H") -AnnotationAssertion( "InChI=1S/H") -AnnotationAssertion( "YZCKVEUIGOORGS-UHFFFAOYSA-N") -AnnotationAssertion( "1.00794") -AnnotationAssertion( "1.00783") -AnnotationAssertion( "[H]") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "atomic hydrogen") -AnnotationAssertion( "CHEBI:33251") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "monoatomic hydrogen") -SubClassOf( ) -SubClassOf( ) - # Class: (atomic nucleus) AnnotationAssertion( "A nucleus is the positively charged central portion of an atom, excluding the orbital electrons.") @@ -23617,38 +11549,6 @@ AnnotationAssertion( "elemental molecular entity") SubClassOf( ) -# Class: (elemental hydrogen) - -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion( "CHEBI:33260") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "elemental hydrogen") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (elemental oxygen) - -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion( "CHEBI:33262") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "elemental oxygen") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (diatomic oxygen) - -AnnotationAssertion( "0") -AnnotationAssertion( "O2") -AnnotationAssertion( "31.999") -AnnotationAssertion( "31.98983") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion( "CHEBI:33263") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "diatomic oxygen") -SubClassOf( ) - # Class: (polyatomic anion) AnnotationAssertion( "An anion consisting of more than one atom.") @@ -23669,45 +11569,6 @@ AnnotationAssertion( "molecular messenger") SubClassOf( ) -# Class: (antimicrobial agent) - -AnnotationAssertion( "A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans.") -AnnotationAssertion( "CHEBI:22582") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:12964249") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:22117953") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:22439833") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:22849268") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:22849276") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:22958833") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "Antibiotika") -AnnotationAssertion(Annotation( "ChEBI") "Antibiotikum") -AnnotationAssertion(Annotation( "ChEBI") "antibiotic") -AnnotationAssertion(Annotation( "ChEBI") "antibiotics") -AnnotationAssertion(Annotation( "IUPAC") "antibiotique") -AnnotationAssertion(Annotation( "ChEBI") "antimicrobial") -AnnotationAssertion(Annotation( "ChEBI") "antimicrobial agents") -AnnotationAssertion(Annotation( "ChEBI") "antimicrobials") -AnnotationAssertion(Annotation( "ChEBI") "microbicide") -AnnotationAssertion(Annotation( "ChEBI") "microbicides") -AnnotationAssertion( "CHEBI:33281") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "antimicrobial agent") -SubClassOf( ) - -# Class: (antibacterial agent) - -AnnotationAssertion( "A substance (or active part thereof) that kills or slows the growth of bacteria.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "antibacterial agents") -AnnotationAssertion(Annotation( "ChEBI") "antibacterials") -AnnotationAssertion(Annotation( "ChEBI") "bactericide") -AnnotationAssertion(Annotation( "ChEBI") "bactericides") -AnnotationAssertion( "CHEBI:33282") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "antibacterial agent") -SubClassOf( ) - # Class: (nutrient) AnnotationAssertion( "A nutrient is a food component that an organism uses to survive and grow.") @@ -23754,32 +11615,6 @@ AnnotationAssertion( "fertilizer") SubClassOf( ) -# Class: (food) - -AnnotationAssertion( "A physiological role played by any substance of either plant, animal or artificial origin which contains essential body nutrients that can be ingested by an organism to provide energy, promote growth, and maintain the processes of life.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "food material") -AnnotationAssertion(Annotation( "ChEBI") "food materials") -AnnotationAssertion(Annotation( "ChEBI") "food role") -AnnotationAssertion(Annotation( "ChEBI") "foods") -AnnotationAssertion(Annotation( "ChEBI") "foodstuff") -AnnotationAssertion(Annotation( "ChEBI") "foodstuffs") -AnnotationAssertion( "CHEBI:33290") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "food") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (diagnostic agent) - -AnnotationAssertion( "A substance administered to aid diagnosis of a disease.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "diagnostic aid") -AnnotationAssertion( "CHEBI:33295") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "diagnostic agent") -SubClassOf( ) - # Class: (alkali metal molecular entity) AnnotationAssertion( "A molecular entity containing one or more atoms of an alkali metal.") @@ -23883,30 +11718,6 @@ AnnotationAssertion( "carbon group element atom") SubClassOf( ) -# Class: (carboxylic ester) - -AnnotationAssertion( "An ester of a carboxylic acid, R(1)C(=O)OR(2), where R(1) = H or organyl and R(2) = organyl.") -AnnotationAssertion( "0") -AnnotationAssertion( "CO2R2") -AnnotationAssertion( "44.010") -AnnotationAssertion( "43.98983") -AnnotationAssertion( "[*]C(=O)O[*]") -AnnotationAssertion( "CHEBI:13204") -AnnotationAssertion( "CHEBI:23028") -AnnotationAssertion( "CHEBI:3408") -AnnotationAssertion( "KEGG:C02391") -AnnotationAssertion( "Wikipedia:Ester") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Carboxylic ester") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "carboxylic esters") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "UniProt") "a carboxylic ester") -AnnotationAssertion(Annotation( "ChEBI") "carboxylic acid esters") -AnnotationAssertion( "CHEBI:33308") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "carboxylic ester") -SubClassOf( ) -SubClassOf( ) - # Class: (main group element atom) AnnotationAssertion( "An atom belonging to one of the main groups (found in the s- and p- blocks) of the periodic table.") @@ -23920,18 +11731,6 @@ AnnotationAssertion( "main group element atom") SubClassOf( ) -# Class: (iron group element atom) - -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "group 8 elements") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "iron group element") -AnnotationAssertion(Annotation( "ChEBI") "iron group elements") -AnnotationAssertion( "CHEBI:33356") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "iron group element atom") -SubClassOf( ) -SubClassOf( ) - # Class: (sulfur oxoacid) AnnotationAssertion( "chebi_ontology") @@ -23965,29 +11764,6 @@ AnnotationAssertion(rdfs:label "sul SubClassOf( ) SubClassOf( ) -# Class: (phospho sugar) - -AnnotationAssertion( "Any monosaccharide containing an alcoholic hydroxy group esterified with phosphoric acid.") -AnnotationAssertion( "CHEBI:15132") -AnnotationAssertion( "CHEBI:25406") -AnnotationAssertion( "CHEBI:26086") -AnnotationAssertion( "CHEBI:9320") -AnnotationAssertion( "KEGG:C00934") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:18186488") -AnnotationAssertion(Annotation( "ChEBI") "phospho sugar") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "monosaccharide phosphates") -AnnotationAssertion(Annotation( "ChEBI") "phospho sugars") -AnnotationAssertion(Annotation( "ChEBI") "phosphorylated sugar") -AnnotationAssertion(Annotation( "ChEBI") "phosphorylated sugars") -AnnotationAssertion(Annotation( "ChEBI") "phosphosugar") -AnnotationAssertion(Annotation( "ChEBI") "phosphosugars") -AnnotationAssertion( "CHEBI:33447") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "phospho sugar") -SubClassOf( ) -SubClassOf( ) - # Class: (phosphorus oxoacid) AnnotationAssertion( "A pnictogen oxoacid which contains phosphorus and oxygen, at least one hydrogen atom bound to oxygen, and forms an ion by the loss of one or more protons.") @@ -24061,18 +11837,6 @@ AnnotationAssertion(rdfs:label "cha SubClassOf( ) SubClassOf( ) -# Class: (transition element molecular entity) - -AnnotationAssertion( "A molecular entity containing one or more atoms of a transition element.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "transition element molecular entities") -AnnotationAssertion(Annotation( "ChEBI") "transition metal molecular entity") -AnnotationAssertion( "CHEBI:33497") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "transition element molecular entity") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (alkali metal cation) AnnotationAssertion( "chebi_ontology") @@ -24094,16 +11858,6 @@ AnnotationAssertion(rdfs:label "alk SubClassOf( ) SubClassOf( ) -# Class: (transition element cation) - -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "transition element cations") -AnnotationAssertion(Annotation( "ChEBI") "transition metal cation") -AnnotationAssertion( "CHEBI:33515") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "transition element cation") -SubClassOf( ) - # Class: (metal atom) AnnotationAssertion( "An atom of an element that exhibits typical metallic properties, being typically shiny, with high electrical and thermal conductivity.") @@ -24157,17 +11911,6 @@ AnnotationAssertion( "p-block element atom") SubClassOf( ) -# Class: (d-block element atom) - -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "d-block element") -AnnotationAssertion(Annotation( "ChEBI") "d-block elements") -AnnotationAssertion( "CHEBI:33561") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "d-block element atom") -SubClassOf( ) -SubClassOf( ) - # Class: (glycolipid) AnnotationAssertion( "Any member of class of 1,2-di-O-acylglycerols joined at oxygen 3 by a glycosidic linkage to a carbohydrate part (usually a mono-, di- or tri-saccharide). Some substances classified as bacterial glycolipids have the sugar part acylated by one or more fatty acids and the glycerol part may be absent.") @@ -24183,141 +11926,6 @@ AnnotationAssertion( "glycolipid") SubClassOf( ) -# Class: (catechols) - -AnnotationAssertion( "Any compound containing an o-diphenol component.") -AnnotationAssertion( "0") -AnnotationAssertion( "C6H2O2R4") -AnnotationAssertion( "106.079") -AnnotationAssertion( "106.00548") -AnnotationAssertion( "OC1=C(O)C(*)=C(*)C(*)=C1*") -AnnotationAssertion( "CHEBI:134187") -AnnotationAssertion( "CHEBI:13628") -AnnotationAssertion( "CHEBI:18862") -AnnotationAssertion( "KEGG:C15571") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "1,2-benzenediols") -AnnotationAssertion(Annotation( "UniProt") "a catechol") -AnnotationAssertion(Annotation( "ChEBI") "benzene-1,2-diols") -AnnotationAssertion( "CHEBI:33566") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "catechols") -SubClassOf( ) - -# Class: (catecholamine) - -AnnotationAssertion( "4-(2-Aminoethyl)pyrocatechol [4-(2-aminoethyl)benzene-1,2-diol] and derivatives formed by substitution.") -AnnotationAssertion( "0") -AnnotationAssertion( "C8H9NO2R2") -AnnotationAssertion( "151.163") -AnnotationAssertion( "151.06333") -AnnotationAssertion( "CHEBI:23056") -AnnotationAssertion( "CHEBI:3468") -AnnotationAssertion( "KEGG:C02012") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Catecholamine") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "catecholamines") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "catecholamines") -AnnotationAssertion( "CHEBI:33567") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "catecholamine") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (adrenaline) - -AnnotationAssertion( "A racemate comprising equimolar amounts of (R)-adrenaline and (S)-adrenaline.") -AnnotationAssertion( "0") -AnnotationAssertion( "C9H13NO3") -AnnotationAssertion( "183.207") -AnnotationAssertion( "183.08954") -AnnotationAssertion(Annotation( "ChemIDplus") "Beilstein:2212160") -AnnotationAssertion(Annotation( "ChemIDplus") "CAS:329-65-7") -AnnotationAssertion(Annotation( "DrugCentral") "Drug_Central:4508") -AnnotationAssertion(Annotation( "Gmelin") "Gmelin:51559") -AnnotationAssertion( "LINCS:LSM-4958") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:10052027") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:24252294") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:24719616") -AnnotationAssertion(Annotation( "Reaxys") "Reaxys:2212160") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "rac-4-[1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "IUPHAR") "(+-)-adrenaline") -AnnotationAssertion(Annotation( "ChemIDplus") "(+-)-epinephrine") -AnnotationAssertion(Annotation( "ChemIDplus") "2-(methylamino)-1-(3,4-dihydroxyphenyl)ethanol") -AnnotationAssertion(Annotation( "ChemIDplus") "dl-adrenaline") -AnnotationAssertion(Annotation( "ChemIDplus") "epinephrine racemic") -AnnotationAssertion(Annotation( "ChEBI") "rac-adrenaline") -AnnotationAssertion(Annotation( "ChEBI") "racemic adrenaline") -AnnotationAssertion(Annotation( "ChemIDplus") Annotation( ) "racepinefrina") -AnnotationAssertion(Annotation( "ChemIDplus") Annotation( ) "racepinefrine") -AnnotationAssertion(Annotation( "ChemIDplus") Annotation( ) "racepinefrinum") -AnnotationAssertion( "CHEBI:33568") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "adrenaline") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (noradrenaline) - -AnnotationAssertion( "A catecholamine in which C-1 of the aminoethyl side-chain is hydroxy-substituted.") -AnnotationAssertion( "0") -AnnotationAssertion( "C8H11NO3") -AnnotationAssertion( "InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2") -AnnotationAssertion( "SFLSHLFXELFNJZ-UHFFFAOYSA-N") -AnnotationAssertion( "169.17788") -AnnotationAssertion( "169.07389") -AnnotationAssertion( "NCC(O)c1ccc(O)c(O)c1") -AnnotationAssertion(Annotation( "Beilstein") "Beilstein:2210994") -AnnotationAssertion(Annotation( "ChemIDplus") "CAS:138-65-8") -AnnotationAssertion(Annotation( "NIST Chemistry WebBook") "CAS:138-65-8") -AnnotationAssertion(Annotation( "Gmelin") "Gmelin:863925") -AnnotationAssertion( "LINCS:LSM-5181") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "4-(2-amino-1-hydroxyethyl)benzene-1,2-diol") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "noradrenalina") -AnnotationAssertion(Annotation( "ChEBI") "norepinephrine") -AnnotationAssertion( "CHEBI:33569") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "noradrenaline") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (benzenediols) - -AnnotationAssertion( "CHEBI:22705") -AnnotationAssertion( "CHEBI:22711") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion( "CHEBI:33570") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "benzenediols") -SubClassOf( ) - -# Class: ((S)-noradrenaline) - -AnnotationAssertion( "The S-enantiomer of noradrenaline.") -AnnotationAssertion( "0") -AnnotationAssertion( "C8H11NO3") -AnnotationAssertion( "InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2/t8-/m1/s1") -AnnotationAssertion( "SFLSHLFXELFNJZ-MRVPVSSYSA-N") -AnnotationAssertion( "169.17788") -AnnotationAssertion( "169.07389") -AnnotationAssertion( "NC[C@@H](O)c1ccc(O)c(O)c1") -AnnotationAssertion(Annotation( "Beilstein") "Beilstein:2937999") -AnnotationAssertion( "LINCS:LSM-37072") -AnnotationAssertion(Annotation( "Reaxys") "Reaxys:2937999") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "4-[(1S)-2-amino-1-hydroxyethyl]benzene-1,2-diol") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion( "CHEBI:33571") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "(S)-noradrenaline") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (carboxylic acid) AnnotationAssertion( "A carbon oxoacid acid carrying at least one -C(=O)OH group and having the structure RC(=O)OH, where R is any any monovalent functional group. Carboxylic acids are the most common type of organic acid.") @@ -24406,16 +12014,6 @@ AnnotationAssertion( "polycyclic compound") SubClassOf( ) -# Class: (bicyclic compound) - -AnnotationAssertion( "A molecule that features two fused rings.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "bicyclic compounds") -AnnotationAssertion( "CHEBI:33636") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "bicyclic compound") -SubClassOf( ) - # Class: (aliphatic compound) AnnotationAssertion( "Any acyclic or cyclic, saturated or unsaturated carbon compound, excluding aromatic compounds.") @@ -24449,49 +12047,6 @@ AnnotationAssertion(rdfs:label "org SubClassOf( ) SubClassOf( ) -# Class: (monocyclic compound) - -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "monocyclic compounds") -AnnotationAssertion( "CHEBI:33661") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "monocyclic compound") -SubClassOf( ) - -# Class: (heteromonocyclic compound) - -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "heteromonocyclic compound") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "heteromonocyclic compounds") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion( "CHEBI:33670") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "heteromonocyclic compound") -SubClassOf( ) -SubClassOf( ) - -# Class: (heteropolycyclic compound) - -AnnotationAssertion( "A polycyclic compound in which at least one of the rings contains at least one non-carbon atom.") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "heteropolycyclic compounds") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "polyheterocyclic compounds") -AnnotationAssertion( "CHEBI:33671") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "heteropolycyclic compound") -SubClassOf( ) -SubClassOf( ) - -# Class: (heterobicyclic compound) - -AnnotationAssertion( "A bicyclic compound in which at least one of the rings contains at least one skeletal heteroatom.") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "heterobicyclic compounds") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion( "CHEBI:33672") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "heterobicyclic compound") -SubClassOf( ) -SubClassOf( ) - # Class: (s-block molecular entity) AnnotationAssertion( "An s-block molecular entity is a molecular entity containing one or more atoms of an s-block element.") @@ -24518,19 +12073,6 @@ AnnotationAssertion(rdfs:label "p-b SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (d-block molecular entity) - -AnnotationAssertion( "A d-block molecular entity is a molecular entity containing one or more atoms of a d-block element.") -AnnotationAssertion(Annotation( "ChEBI") "d-block molecular entity") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "d-block compounds") -AnnotationAssertion(Annotation( "ChEBI") "d-block molecular entities") -AnnotationAssertion( "CHEBI:33676") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "d-block molecular entity") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (hydrides) AnnotationAssertion( "Hydrides are chemical compounds of hydrogen with other chemical elements.") @@ -24541,17 +12083,6 @@ AnnotationAssertion(rdfs:label "hyd SubClassOf( ) SubClassOf( ) -# Class: (oxygen hydride) - -AnnotationAssertion(Annotation( "ChEBI") "oxygen hydride") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "hydrides of oxygen") -AnnotationAssertion(Annotation( "ChEBI") "oxygen hydrides") -AnnotationAssertion( "CHEBI:33693") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "oxygen hydride") -SubClassOf( ) - # Class: (biomacromolecule) AnnotationAssertion( "A macromolecule formed by a living organism.") @@ -24580,47 +12111,6 @@ AnnotationAssertion( "information biomacromolecule") SubClassOf( ) -# Class: (nucleic acid) - -AnnotationAssertion( "A macromolecule made up of nucleotide units and hydrolysable into certain pyrimidine or purine bases (usually adenine, cytosine, guanine, thymine, uracil), D-ribose or 2-deoxy-D-ribose and phosphoric acid.") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "nucleic acids") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "NA") -AnnotationAssertion(Annotation( "ChEBI") "Nukleinsaeure") -AnnotationAssertion(Annotation( "ChEBI") "Nukleinsaeuren") -AnnotationAssertion(Annotation( "ChEBI") "acide nucleique") -AnnotationAssertion(Annotation( "ChEBI") "acides nucleiques") -AnnotationAssertion(Annotation( "ChEBI") "acido nucleico") -AnnotationAssertion(Annotation( "ChEBI") "acidos nucleicos") -AnnotationAssertion( "CHEBI:33696") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "nucleic acid") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (ribonucleic acid) - -AnnotationAssertion( "High molecular weight, linear polymers, composed of nucleotides containing ribose and linked by phosphodiester bonds; RNA is central to the synthesis of proteins.") -AnnotationAssertion(Annotation( "ChemIDplus") "CAS:63231-63-0") -AnnotationAssertion(Annotation( "IUPAC") "ribonucleic acid") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "ribonucleic acids") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "IUPAC") "RNA") -AnnotationAssertion(Annotation( "UniProt") "RNA") -AnnotationAssertion(Annotation( "ChEBI") "RNS") -AnnotationAssertion(Annotation( "ChEBI") "Ribonukleinsaeure") -AnnotationAssertion(Annotation( "ChemIDplus") "pentosenucleic acids") -AnnotationAssertion(Annotation( "ChEBI") "ribonucleic acids") -AnnotationAssertion(Annotation( "ChEBI") "ribose nucleic acid") -AnnotationAssertion(Annotation( "ChEBI") "yeast nucleic acid") -AnnotationAssertion( "CHEBI:33697") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "ribonucleic acid") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (proteinogenic amino-acid residue) AnnotationAssertion( "chebi_ontology") @@ -24674,18 +12164,6 @@ SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (gamma-amino acid) - -AnnotationAssertion( "A non-proteinogenic amino-acid in which the amino group is located on the carbon atom at the position gamma to the carboxy group.") -AnnotationAssertion(Annotation( "ChEBI") "gamma-amino acid") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "gamma-amino acids") -AnnotationAssertion( "CHEBI:33707") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "gamma-amino acid") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (amino-acid residue) AnnotationAssertion( "When two or more amino acids combine to form a peptide, the elements of water are removed, and what remains of each amino acid is called an amino-acid residue.") @@ -24750,72 +12228,6 @@ AnnotationAssertion(rdfs:label "car SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (iron group molecular entity) - -AnnotationAssertion(Annotation( "ChEBI") "iron group molecular entity") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "iron group molecular entities") -AnnotationAssertion( "CHEBI:33744") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "iron group molecular entity") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (canonical nucleoside residue) - -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "canonical nucleoside residues") -AnnotationAssertion(Annotation( "CBN") "common nucleoside residues") -AnnotationAssertion(Annotation( "CBN") "nucleoside residue") -AnnotationAssertion(Annotation( "ChEBI") "standard nucleoside residues") -AnnotationAssertion( "CHEBI:33791") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "canonical nucleoside residue") -SubClassOf( ) - -# Class: (canonical ribonucleoside residue) - -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "CBN") "N") -AnnotationAssertion(Annotation( "CBN") "Nuc") -AnnotationAssertion(Annotation( "ChEBI") "canonical ribonucleoside residues") -AnnotationAssertion(Annotation( "CBN") "common ribonucleoside residue") -AnnotationAssertion(Annotation( "CBN") "common ribonucleoside residues") -AnnotationAssertion(Annotation( "ChEBI") "standard ribonucleoside residues") -AnnotationAssertion( "CHEBI:33792") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "canonical ribonucleoside residue") -SubClassOf( ) - -# Class: (canonical deoxyribonucleoside residue) - -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "canonical deoxyribonucleoside residues") -AnnotationAssertion(Annotation( "CBN") "common 2'-deoxyribonucleoside residue") -AnnotationAssertion(Annotation( "CBN") "common 2'-deoxyribonucleoside residues") -AnnotationAssertion(Annotation( "CBN") "dN") -AnnotationAssertion(Annotation( "CBN") "dNuc") -AnnotationAssertion(Annotation( "ChEBI") "standard deoxyribonucleoside residues") -AnnotationAssertion( "CHEBI:33793") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "canonical deoxyribonucleoside residue") -SubClassOf( ) - -# Class: (organic hydroxy compound) - -AnnotationAssertion( "An organic compound having at least one hydroxy group attached to a carbon atom.") -AnnotationAssertion( "CHEBI:64710") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "hydroxy compounds") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "organic alcohol") -AnnotationAssertion(Annotation( "ChEBI") "organic hydroxy compounds") -AnnotationAssertion( "CHEBI:33822") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "organic hydroxy compound") -SubClassOf( ) -SubClassOf( ) - # Class: (organic cyclic compound) AnnotationAssertion( "Any organic molecule that consists of atoms connected in the form of a ring.") @@ -24851,32 +12263,6 @@ AnnotationAssertion( "conjugated protein") SubClassOf( ) -# Class: (nucleoside) - -AnnotationAssertion( "An N-glycosyl compound that has both a nucleobase, normally adenine, guanine, xanthine, thymine, cytosine or uracil, and either a ribose or deoxyribose as functional parents.") -AnnotationAssertion( "0") -AnnotationAssertion( "C5H8O3R2") -AnnotationAssertion( "116.115") -AnnotationAssertion( "116.04734") -AnnotationAssertion( "[C@H]1([C@H]([C@@H](*)[C@@H](O1)*)O)CO") -AnnotationAssertion( "CHEBI:13661") -AnnotationAssertion( "CHEBI:25611") -AnnotationAssertion( "CHEBI:7647") -AnnotationAssertion( "KEGG:C00801") -AnnotationAssertion( "Wikipedia:Nucleoside") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Nucleoside") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "nucleosides") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "UniProt") "a nucleoside") -AnnotationAssertion(Annotation( "ChEBI") "nucleosides") -AnnotationAssertion( "CHEBI:33838") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "nucleoside") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (macromolecule) AnnotationAssertion( "A macromolecule is a molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.") @@ -24892,32 +12278,6 @@ AnnotationAssertion( "macromolecule") SubClassOf( ) -# Class: (phenols) - -AnnotationAssertion( "Organic aromatic compounds having one or more hydroxy groups attached to a benzene or other arene ring.") -AnnotationAssertion( "0") -AnnotationAssertion( "C6HOR5") -AnnotationAssertion( "89.072") -AnnotationAssertion( "89.00274") -AnnotationAssertion( "C1(=C(C(=C(C(=C1*)*)*)*)*)O") -AnnotationAssertion( "CHEBI:13664") -AnnotationAssertion( "CHEBI:13825") -AnnotationAssertion( "CHEBI:25969") -AnnotationAssertion( "CHEBI:2857") -AnnotationAssertion( "KEGG:C15584") -AnnotationAssertion( "MetaCyc:Phenols") -AnnotationAssertion( "Wikipedia:Phenols") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "phenols") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Aryl alcohol") -AnnotationAssertion(Annotation( "UniProt") "a phenol") -AnnotationAssertion(Annotation( "IUPAC") "arenols") -AnnotationAssertion( "CHEBI:33853") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "phenols") -SubClassOf( ) -SubClassOf( ) - # Class: (reagent) AnnotationAssertion( "A substance used in a chemical reaction to detect, measure, examine, or produce other substances.") @@ -24931,32 +12291,6 @@ AnnotationAssertion( "reagent") SubClassOf( ) -# Class: (aldopentose) - -AnnotationAssertion( "A pentose with a (potential) aldehyde group at one end.") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:10723607") -AnnotationAssertion(Annotation( "ChEBI") "aldopentose") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "aldopentoses") -AnnotationAssertion( "CHEBI:33916") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "aldopentose") -SubClassOf( ) -SubClassOf( ) - -# Class: (aldohexose) - -AnnotationAssertion( "A hexose with a (potential) aldehyde group at one end.") -AnnotationAssertion( "CHEBI:2558") -AnnotationAssertion(Annotation( "ChEBI") "aldohexose") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "aldohexoses") -AnnotationAssertion( "CHEBI:33917") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "aldohexose") -SubClassOf( ) -SubClassOf( ) - # Class: (macronutrient) AnnotationAssertion( "Any nutrient required in large quantities by organisms throughout their life in order to orchestrate a range of physiological functions. Macronutrients are usually chemical elements (carbon, hydrogen, nitrogen, oxygen, phosphorus and sulfur) that humans consume in the largest quantities. Calcium, sodium, magnesium and potassium are sometimes included as macronutrients because they are required in relatively large quantities compared with other vitamins and minerals.") @@ -24967,44 +12301,6 @@ AnnotationAssertion( "macronutrient") SubClassOf( ) -# Class: (ribose) - -AnnotationAssertion( "Any aldopentose where the open-chain form has all the hydroxy groups on the same side in the Fischer projection. Occurrs in two enantiomeric forms, D- and L-ribose, of which only the former is found in nature.") -AnnotationAssertion( "0") -AnnotationAssertion( "C5H10O5") -AnnotationAssertion( "150.130") -AnnotationAssertion( "150.05282") -AnnotationAssertion( "CHEBI:26564") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "ribo-pentose") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "ribose") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "JCBN") "Rib") -AnnotationAssertion( "CHEBI:33942") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "ribose") -SubClassOf( ) - -# Class: (serotonin(1+)) - -AnnotationAssertion( "An ammonium ion that is the conjugate acid of serotonin; major species at pH 7.3.") -AnnotationAssertion( "+1") -AnnotationAssertion( "C10H13N2O") -AnnotationAssertion( "InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2/p+1") -AnnotationAssertion( "QZAYGJVTTNCVMB-UHFFFAOYSA-O") -AnnotationAssertion( "177.22250") -AnnotationAssertion( "177.10224") -AnnotationAssertion( "[NH3+]CCc1c[nH]c2ccc(O)cc12") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "2-(5-hydroxy-1H-indol-3-yl)ethanaminium") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "UniProt") "serotonin") -AnnotationAssertion(Annotation( "ChEBI") "serotonin cation") -AnnotationAssertion( "CHEBI:350546") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "serotonin(1+)") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (nitrogen hydride) AnnotationAssertion( "chebi_ontology") @@ -25025,15 +12321,6 @@ AnnotationAssertion( "azane") SubClassOf( ) -# Class: (aldose phosphate) - -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "aldose phosphates") -AnnotationAssertion( "CHEBI:35131") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "aldose phosphate") -SubClassOf( ) - # Class: ((6'R)-beta,epsilon-carotene) AnnotationAssertion( "0") @@ -25257,26 +12544,6 @@ AnnotationAssertion(rdfs:label "amm SubClassOf( ) SubClassOf( ) -# Class: (acylcholine) - -AnnotationAssertion( "A choline ester formed from choline and a carboxylic acid.") -AnnotationAssertion( "+1") -AnnotationAssertion( "C6H13NO2R") -AnnotationAssertion( "131.17290") -AnnotationAssertion( "131.09463") -AnnotationAssertion( "C[N+](C)(C)CCOC([*])=O") -AnnotationAssertion( "CHEBI:13245") -AnnotationAssertion( "CHEBI:22227") -AnnotationAssertion( "CHEBI:2463") -AnnotationAssertion( "KEGG:C01777") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "acylcholines") -AnnotationAssertion(Annotation( "UniProt") "an acylcholine") -AnnotationAssertion( "CHEBI:35287") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "acylcholine") -SubClassOf( ) - # Class: (steroid) AnnotationAssertion( "Any of naturally occurring compounds and synthetic analogues, based on the cyclopenta[a]phenanthrene carbon skeleton, partially or completely hydrogenated; there are usually methyl groups at C-10 and C-13, and often an alkyl group at C-17. By extension, one or more bond scissions, ring expansions and/or ring contractions of the skeleton may have occurred. Natural steroids are derived biogenetically from squalene which is a triterpene.") @@ -25300,80 +12567,6 @@ AnnotationAssertion(rdfs:label "ste SubClassOf( ) SubClassOf( ) -# Class: (17beta-hydroxy steroid) - -AnnotationAssertion( "A 17-hydroxy steroid in which the hydroxy group at position 17 has a beta-configuration.") -AnnotationAssertion( "0") -AnnotationAssertion( "C18H29OR") -AnnotationAssertion( "261.423") -AnnotationAssertion( "261.22184") -AnnotationAssertion( "CC12CCC3C(CCC4CCCCC34[*])C1CC[C@@H]2O") -AnnotationAssertion( "CHEBI:19176") -AnnotationAssertion( "CHEBI:794") -AnnotationAssertion( "KEGG:C03051") -AnnotationAssertion( "MetaCyc:17-beta-Hydroxysteroids") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "17beta-hydroxy steroids") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "17beta-hydroxysteroid") -AnnotationAssertion(Annotation( "ChEBI") "17beta-hydroxysteroids") -AnnotationAssertion(Annotation( "UniProt") "a 17beta-hydroxy steroid") -AnnotationAssertion( "CHEBI:35343") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "17beta-hydroxy steroid") -SubClassOf( ) - -# Class: (21-hydroxy steroid) - -AnnotationAssertion( "CHEBI:1300") -AnnotationAssertion( "CHEBI:13596") -AnnotationAssertion( "CHEBI:19803") -AnnotationAssertion( "KEGG:C02506") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "21-Hydroxysteroid") -AnnotationAssertion(Annotation( "ChEBI") "21-hydroxy steroids") -AnnotationAssertion(Annotation( "ChEBI") "21-hydroxysteroids") -AnnotationAssertion( "CHEBI:35344") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "21-hydroxy steroid") -SubClassOf( ) - -# Class: (11beta-hydroxy steroid) - -AnnotationAssertion( "Any 11-hydroxy steroid in which the hydroxy group at position 11 has beta- configuration.") -AnnotationAssertion( "0") -AnnotationAssertion( "C19H31OR") -AnnotationAssertion( "275.450") -AnnotationAssertion( "275.23749") -AnnotationAssertion( "C12(CCCCC1CCC3C2[C@H](CC4(C3CCC4*)C)O)C") -AnnotationAssertion( "CHEBI:13774") -AnnotationAssertion( "CHEBI:19134") -AnnotationAssertion( "CHEBI:738") -AnnotationAssertion( "KEGG:C01058") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "11beta-Hydroxysteroid") -AnnotationAssertion(Annotation( "ChEBI") "11beta-hydroxy steroids") -AnnotationAssertion(Annotation( "ChEBI") "11beta-hydroxysteroids") -AnnotationAssertion(Annotation( "UniProt") "an 11beta-hydroxysteroid") -AnnotationAssertion( "CHEBI:35346") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "11beta-hydroxy steroid") -SubClassOf( ) - -# Class: (hydroxy steroid) - -AnnotationAssertion( "CHEBI:24748") -AnnotationAssertion( "CHEBI:5814") -AnnotationAssertion( "KEGG:C02159") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Hydroxysteroid") -AnnotationAssertion(Annotation( "ChEBI") "hydroxy steroids") -AnnotationAssertion(Annotation( "ChEBI") "hydroxysteroids") -AnnotationAssertion( "CHEBI:35350") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "hydroxy steroid") -SubClassOf( ) -SubClassOf( ) - # Class: (organonitrogen compound) AnnotationAssertion( "Any heteroorganic entity containing at least one carbon-nitrogen bond.") @@ -25386,57 +12579,6 @@ AnnotationAssertion(rdfs:label "org SubClassOf( ) SubClassOf( ) -# Class: (fatty acid) - -AnnotationAssertion( "Any aliphatic monocarboxylic acid derived from or contained in esterified form in an animal or vegetable fat, oil or wax. Natural fatty acids commonly have a chain of 4 to 28 carbons (usually unbranched and even-numbered), which may be saturated or unsaturated. By extension, the term is sometimes used to embrace all acyclic aliphatic carboxylic acids.") -AnnotationAssertion( "0") -AnnotationAssertion( "CHO2R") -AnnotationAssertion( "45.01740") -AnnotationAssertion( "44.99765") -AnnotationAssertion( "OC([*])=O") -AnnotationAssertion( "CHEBI:13633") -AnnotationAssertion( "CHEBI:24024") -AnnotationAssertion( "CHEBI:4984") -AnnotationAssertion( "KEGG:C00162") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:14287444") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:14300208") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:14328676") -AnnotationAssertion( "Wikipedia:Fatty_acid") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Fatty acid") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "fatty acids") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "Fettsaeure") -AnnotationAssertion(Annotation( "ChEBI") "Fettsaeuren") -AnnotationAssertion(Annotation( "ChEBI") "acide gras") -AnnotationAssertion(Annotation( "ChemIDplus") "acides gras") -AnnotationAssertion(Annotation( "ChEBI") "acido graso") -AnnotationAssertion(Annotation( "ChEBI") "acidos grasos") -AnnotationAssertion(Annotation( "ChEBI") "fatty acids") -AnnotationAssertion( "CHEBI:35366") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "fatty acid") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (monosaccharide) - -AnnotationAssertion( "Parent monosaccharides are polyhydroxy aldehydes H[CH(OH)]nC(=O)H or polyhydroxy ketones H-[CHOH]n-C(=O)[CHOH]m-H with three or more carbon atoms. The generic term 'monosaccharide' (as opposed to oligosaccharide or polysaccharide) denotes a single unit, without glycosidic connection to other such units. It includes aldoses, dialdoses, aldoketoses, ketoses and diketoses, as well as deoxy sugars, provided that the parent compound has a (potential) carbonyl group.") -AnnotationAssertion( "CHEBI:25407") -AnnotationAssertion( "CHEBI:6984") -AnnotationAssertion( "KEGG:C06698") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Monosaccharide") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "monosaccharides") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "Monosaccharid") -AnnotationAssertion(Annotation( "ChEBI") "Monosacharid") -AnnotationAssertion(Annotation( "ChEBI") "monosacarido") -AnnotationAssertion(Annotation( "IUPAC") "monosacaridos") -AnnotationAssertion( "CHEBI:35381") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "monosaccharide") -SubClassOf( ) - # Class: (oxoanion) AnnotationAssertion( "An oxoanion is an anion derived from an oxoacid by loss of hydron(s) bound to oxygen.") @@ -25452,32 +12594,6 @@ AnnotationAssertion(rdfs:label "oxo SubClassOf( ) SubClassOf( ) -# Class: (central nervous system drug) - -AnnotationAssertion( "A class of drugs producing both physiological and psychological effects through a variety of mechanisms involving the central nervous system.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "CNS agent") -AnnotationAssertion(Annotation( "ChEBI") "CNS drugs") -AnnotationAssertion(Annotation( "ChEBI") "central nervous system agents") -AnnotationAssertion( "CHEBI:35470") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "central nervous system drug") -SubClassOf( ) - -# Class: (anti-inflammatory drug) - -AnnotationAssertion( "A substance that reduces or suppresses inflammation.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "anti-inflammatory drugs") -AnnotationAssertion(Annotation( "ChEBI") "antiinflammatory agent") -AnnotationAssertion(Annotation( "ChEBI") "antiinflammatory drug") -AnnotationAssertion(Annotation( "ChEBI") "antiinflammatory drugs") -AnnotationAssertion( "CHEBI:35472") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "anti-inflammatory drug") -SubClassOf( ) -SubClassOf( ) - # Class: (alkali metal salt) AnnotationAssertion( "chebi_ontology") @@ -25488,27 +12604,6 @@ AnnotationAssertion(rdfs:label "alk SubClassOf( ) SubClassOf( ) -# Class: (analgesic) - -AnnotationAssertion( "An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion( "CHEBI:35480") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "analgesic") -SubClassOf( ) -SubClassOf( ) - -# Class: (central nervous system depressant) - -AnnotationAssertion( "A loosely defined group of drugs that tend to reduce the activity of the central nervous system.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "CNS depressants") -AnnotationAssertion(Annotation( "ChEBI") "central nervous system depressants") -AnnotationAssertion( "CHEBI:35488") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "central nervous system depressant") -SubClassOf( ) - # Class: (natural product fundamental parent) AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "natural product fundamental parents") @@ -25528,25 +12623,6 @@ AnnotationAssertion(rdfs:label "ste SubClassOf( ) SubClassOf( ) -# Class: (androstane) - -AnnotationAssertion( "0") -AnnotationAssertion( "C19H32") -AnnotationAssertion( "InChI=1S/C19H32/c1-18-11-5-7-16(18)15-9-8-14-6-3-4-12-19(14,2)17(15)10-13-18/h14-17H,3-13H2,1-2H3/t14?,15-,16-,17-,18-,19-/m0/s1") -AnnotationAssertion( "QZLYKIGBANMMBK-FZFXZXLVSA-N") -AnnotationAssertion( "260.45738") -AnnotationAssertion( "260.25040") -AnnotationAssertion( "[H][C@@]12CCC3CCCC[C@]3(C)[C@@]1([H])CC[C@]1(C)CCC[C@@]21[H]") -AnnotationAssertion(Annotation( "Beilstein") "Beilstein:5247532") -AnnotationAssertion(Annotation( "ChemIDplus") "CAS:24887-75-0") -AnnotationAssertion(Annotation( "LIPID MAPS") "LIPID_MAPS_instance:LMST02020000") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "androstane") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion( "CHEBI:35509") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "androstane") -SubClassOf( ) - # Class: (cholane) AnnotationAssertion( "0") @@ -25563,54 +12639,6 @@ AnnotationAssertion( "cholane") SubClassOf( ) -# Class: (beta-adrenergic agonist) - -AnnotationAssertion( "An agent that selectively binds to and activates beta-adrenergic receptors.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "beta-adrenergic agonists") -AnnotationAssertion(Annotation( "ChEBI") "beta-adrenergic receptor agonist") -AnnotationAssertion(Annotation( "IUPHAR") "beta-adrenoceptor agonists") -AnnotationAssertion( "CHEBI:35522") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "beta-adrenergic agonist") -SubClassOf( ) -SubClassOf( ) - -# Class: (bronchodilator agent) - -AnnotationAssertion( "An agent that causes an increase in the expansion of a bronchus or bronchial tubes.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "bronchodilator") -AnnotationAssertion(Annotation( "ChEBI") "bronchodilator agents") -AnnotationAssertion(Annotation( "ChEBI") "broncholytic agent") -AnnotationAssertion( "CHEBI:35523") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "bronchodilator agent") -SubClassOf( ) - -# Class: (sympathomimetic agent) - -AnnotationAssertion( "A drug that mimics the effects of stimulating postganglionic adrenergic sympathetic nerves. Included in this class are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "sympathomimetic") -AnnotationAssertion(Annotation( "ChEBI") "sympathomimetics") -AnnotationAssertion( "CHEBI:35524") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "sympathomimetic agent") -SubClassOf( ) - -# Class: (heterocyclic organic fundamental parent) - -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "heterocyclic parent hydrides") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "heterocyclic fundamental parent") -AnnotationAssertion(Annotation( "ChEBI") "heterocyclic organic fundamental parents") -AnnotationAssertion(Annotation( "ChEBI") "organic heterocyclic fundamental parents") -AnnotationAssertion( "CHEBI:35552") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "heterocyclic organic fundamental parent") -SubClassOf( ) - # Class: (cardiovascular drug) AnnotationAssertion( "A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume.") @@ -25622,155 +12650,6 @@ AnnotationAssertion( "cardiovascular drug") SubClassOf( ) -# Class: (mancude ring) - -AnnotationAssertion( "Any molecular entity that consists of a ring having (formally) the maximum number of noncumulative double bonds.") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "mancude-ring systems") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "mancude rings") -AnnotationAssertion(Annotation( "IUPAC") "mancunide-ring systems") -AnnotationAssertion( "CHEBI:35568") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "mancude ring") -SubClassOf( ) - -# Class: (alpha-adrenergic agonist) - -AnnotationAssertion( "An agent that selectively binds to and activates alpha-adrenergic receptors.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "alpha-adrenergic agonists") -AnnotationAssertion(Annotation( "ChEBI") "alpha-adrenergic receptor agonist") -AnnotationAssertion(Annotation( "IUPHAR") "alpha-adrenoceptor agonists") -AnnotationAssertion( "CHEBI:35569") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "alpha-adrenergic agonist") -SubClassOf( ) -SubClassOf( ) - -# Class: (mancude organic heterobicyclic parent) - -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "mancude organic heterobicyclic parents") -AnnotationAssertion(Annotation( "ChEBI") "mancude-ring organic heterobicyclic parents") -AnnotationAssertion( "CHEBI:35570") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "mancude organic heterobicyclic parent") -SubClassOf( ) -SubClassOf( ) - -# Class: (mancude organic heterocyclic parent) - -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "mancude organic heterocyclic parents") -AnnotationAssertion(Annotation( "ChEBI") "mancude-ring organic heterocyclic parents") -AnnotationAssertion( "CHEBI:35571") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "mancude organic heterocyclic parent") -SubClassOf( ) -SubClassOf( ) - -# Class: (organic mancude parent) - -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "organic mancude parents") -AnnotationAssertion(Annotation( "ChEBI") "organic mancude-ring parents") -AnnotationAssertion( "CHEBI:35573") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "organic mancude parent") -SubClassOf( ) -SubClassOf( ) - -# Class: (purine) - -AnnotationAssertion( "A heterobicyclic aromatic organic compound comprising a pyrimidine ring fused to an imidazole ring; the parent compound of the purines.") -AnnotationAssertion( "0") -AnnotationAssertion( "C5H4N4") -AnnotationAssertion( "120.112") -AnnotationAssertion( "120.04360") -AnnotationAssertion( "HMDB:HMDB0001366") -AnnotationAssertion( "KEGG:C15587") -AnnotationAssertion( "MetaCyc:PURINE") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:12865945") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:24088627") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "purine") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion( "CHEBI:35584") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "purine") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (1H-purine) - -AnnotationAssertion( "The 1H-tautomer of purine.") -AnnotationAssertion( "0") -AnnotationAssertion( "C5H4N4") -AnnotationAssertion( "InChI=1S/C5H4N4/c1-4-5(8-2-6-1)9-3-7-4/h1-3H,(H,6,7,8,9)") -AnnotationAssertion( "KDCGOANMDULRCW-UHFFFAOYSA-N") -AnnotationAssertion( "120.11210") -AnnotationAssertion( "120.04360") -AnnotationAssertion( "c1nc2c[nH]cnc2n1") -AnnotationAssertion(Annotation( "Gmelin") "Gmelin:2379911") -AnnotationAssertion(Annotation( "ChEBI") "1H-purine") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion( "CHEBI:35586") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "1H-purine") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (3H-purine) - -AnnotationAssertion( "The 3H-tautomer of purine.") -AnnotationAssertion( "0") -AnnotationAssertion( "C5H4N4") -AnnotationAssertion( "InChI=1S/C5H4N4/c1-4-5(8-2-6-1)9-3-7-4/h1-3H,(H,6,7,8,9)") -AnnotationAssertion( "KDCGOANMDULRCW-UHFFFAOYSA-N") -AnnotationAssertion( "120.11222") -AnnotationAssertion( "120.04360") -AnnotationAssertion( "c1nc2cnc[nH]c2n1") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:6149478") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:7178185") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:7296170") -AnnotationAssertion(Annotation( "Reaxys") "Reaxys:1210196") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "3H-purine") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion( "CHEBI:35588") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "3H-purine") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (9H-purine) - -AnnotationAssertion( "The 9H-tautomer of purine.") -AnnotationAssertion( "0") -AnnotationAssertion( "C5H4N4") -AnnotationAssertion( "InChI=1S/C5H4N4/c1-4-5(8-2-6-1)9-3-7-4/h1-3H,(H,6,7,8,9)") -AnnotationAssertion( "KDCGOANMDULRCW-UHFFFAOYSA-N") -AnnotationAssertion( "120.11222") -AnnotationAssertion( "120.04360") -AnnotationAssertion( "c1ncc2nc[nH]c2n1") -AnnotationAssertion(Annotation( "Beilstein") "Beilstein:606899") -AnnotationAssertion(Annotation( "NIST Chemistry WebBook") "CAS:120-73-0") -AnnotationAssertion(Annotation( "Gmelin") "Gmelin:3120") -AnnotationAssertion( "Wikipedia:Purine") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "9H-purine") -AnnotationAssertion(Annotation( "UniProt") "9H-purine") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion( "CHEBI:35589") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "9H-purine") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (carbon oxoanion) AnnotationAssertion( "A negative ion consisting solely of carbon and oxygen atoms, and therefore having the general formula CxOy(n-) for some integers x, y and n.") @@ -25808,30 +12687,6 @@ AnnotationAssertion( "vasodilator agent") SubClassOf( ) -# Class: (anticonvulsant) - -AnnotationAssertion( "A drug used to prevent seizures or reduce their severity.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "Antiepileptika") -AnnotationAssertion(Annotation( "ChEBI") "Antiepileptikum") -AnnotationAssertion(Annotation( "ChEBI") "Antikonvulsiva") -AnnotationAssertion(Annotation( "ChEBI") "Antikonvulsivum") -AnnotationAssertion(Annotation( "ChEBI") "anti-convulsant") -AnnotationAssertion(Annotation( "ChEBI") "anti-convulsants") -AnnotationAssertion(Annotation( "ChEBI") "anti-convulsive agent") -AnnotationAssertion(Annotation( "ChEBI") "anti-convulsive agents") -AnnotationAssertion(Annotation( "ChEBI") "anticonvulsants") -AnnotationAssertion(Annotation( "ChEBI") "anticonvulsive agent") -AnnotationAssertion(Annotation( "ChEBI") "anticonvulsive agents") -AnnotationAssertion(Annotation( "ChEBI") "antiepileptic") -AnnotationAssertion(Annotation( "ChEBI") "antiepileptics") -AnnotationAssertion(Annotation( "ChEBI") "antiepileptique") -AnnotationAssertion(Annotation( "ChEBI") "antiepileptiques") -AnnotationAssertion( "CHEBI:35623") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "anticonvulsant") -SubClassOf( ) - # Class: (dicarboxylic acid) AnnotationAssertion( "Any carboxylic acid containing two carboxy groups.") @@ -25909,30 +12764,6 @@ AnnotationAssertion(rdfs:label "lip SubClassOf( ) SubClassOf( ) -# Class: (monocarboxylic acid anion) - -AnnotationAssertion( "A carboxylic acid anion formed when the carboxy group of a monocarboxylic acid is deprotonated.") -AnnotationAssertion( "-1") -AnnotationAssertion( "CO2R") -AnnotationAssertion( "44.01000") -AnnotationAssertion( "43.98983") -AnnotationAssertion( "[O-]C([*])=O") -AnnotationAssertion( "CHEBI:13657") -AnnotationAssertion( "CHEBI:25382") -AnnotationAssertion( "CHEBI:3407") -AnnotationAssertion( "KEGG:C00060") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Carboxylate") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Monocarboxylate") -AnnotationAssertion(Annotation( "UniProt") "a monocarboxylate") -AnnotationAssertion(Annotation( "ChEBI") "monocarboxylates") -AnnotationAssertion(Annotation( "ChEBI") "monocarboxylic acid anions") -AnnotationAssertion( "CHEBI:35757") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "monocarboxylic acid anion") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (phosphate ion) AnnotationAssertion( "A phosphorus oxoanion that is the conjugate base of phosphoric acid.") @@ -25959,21 +12790,6 @@ AnnotationAssertion(rdfs:label "pho SubClassOf( ) SubClassOf( ) -# Class: (oxo steroid) - -AnnotationAssertion( "CHEBI:24979") -AnnotationAssertion( "CHEBI:25804") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "keto steroids") -AnnotationAssertion(Annotation( "ChEBI") "ketosteroids") -AnnotationAssertion(Annotation( "ChEBI") "oxo steroids") -AnnotationAssertion(Annotation( "ChEBI") "oxosteroids") -AnnotationAssertion( "CHEBI:35789") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "oxo steroid") -SubClassOf( ) -SubClassOf( ) - # Class: (tetrapyrrole fundamental parent) AnnotationAssertion( "chebi_ontology") @@ -25984,17 +12800,6 @@ AnnotationAssertion(rdfs:label "tet SubClassOf( ) SubClassOf( ) -# Class: (imidazopyrimidine) - -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "imidazopyrimidines") -AnnotationAssertion( "CHEBI:35875") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "imidazopyrimidine") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - # Class: (pnictogen hydride) AnnotationAssertion(Annotation( "ChEBI") "pnictogen hydride") @@ -26006,17 +12811,6 @@ AnnotationAssertion(rdfs:label "pni SubClassOf( ) SubClassOf( ) -# Class: (neurotransmitter agent) - -AnnotationAssertion( "A substance used for its pharmacological action on any aspect of neurotransmitter systems. Neurotransmitter agents include agonists, antagonists, degradation inhibitors, uptake inhibitors, depleters, precursors, and modulators of receptor function.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "neurotransmitter agents") -AnnotationAssertion( "CHEBI:35942") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "neurotransmitter agent") -SubClassOf( ) -SubClassOf( ) - # Class: (cholanoid) AnnotationAssertion( "CHEBI:22867") @@ -26041,76 +12835,9 @@ AnnotationAssertion( "CHEBI:36080") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "protein") -EquivalentClasses( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (bile acid anion) - -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "bile acid anions") -AnnotationAssertion( "CHEBI:36235") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "bile acid anion") -SubClassOf( ) -SubClassOf( ) - -# Class: (cholanic acid) - -AnnotationAssertion( "A steroid acid that consists of cholane having a carboxy group in place of the methyl group at position 24.") -AnnotationAssertion( "0") -AnnotationAssertion( "C24H40O2") -AnnotationAssertion( "InChI=1S/C24H40O2/c1-16(7-12-22(25)26)19-10-11-20-18-9-8-17-6-4-5-14-23(17,2)21(18)13-15-24(19,20)3/h16-21H,4-15H2,1-3H3,(H,25,26)/t16-,17?,18+,19-,20+,21+,23+,24-/m1/s1") -AnnotationAssertion( "RPKLZQLYODPWTM-KBMWBBLPSA-N") -AnnotationAssertion( "360.57320") -AnnotationAssertion( "360.30283") -AnnotationAssertion( "[H][C@@]1(CC[C@@]2([H])[C@]3([H])CCC4CCCC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)CCC(O)=O") -AnnotationAssertion(Annotation( "ChemIDplus") "CAS:25312-65-6") -AnnotationAssertion( "Patent:JP2008069152") -AnnotationAssertion(Annotation( "Reaxys") "Reaxys:13246008") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "cholan-24-oic acid") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion( "CHEBI:36237") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "cholanic acid") -SubClassOf( ) - -# Class: (5beta-cholanic acid) - -AnnotationAssertion( "0") -AnnotationAssertion( "C24H40O2") -AnnotationAssertion( "InChI=1S/C24H40O2/c1-16(7-12-22(25)26)19-10-11-20-18-9-8-17-6-4-5-14-23(17,2)21(18)13-15-24(19,20)3/h16-21H,4-15H2,1-3H3,(H,25,26)/t16-,17+,18+,19-,20+,21+,23+,24-/m1/s1") -AnnotationAssertion( "RPKLZQLYODPWTM-LVVAJZGHSA-N") -AnnotationAssertion( "360.57320") -AnnotationAssertion( "360.30283") -AnnotationAssertion( "[H][C@@]12CCCC[C@]1(C)[C@@]1([H])CC[C@]3(C)[C@]([H])(CC[C@@]3([H])[C@]1([H])CC2)[C@H](C)CCC(O)=O") -AnnotationAssertion(Annotation( "Beilstein") "Beilstein:3214794") -AnnotationAssertion(Annotation( "ChemIDplus") "CAS:546-18-9") -AnnotationAssertion(Annotation( "LIPID MAPS") "LIPID_MAPS_instance:LMST04010441") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "5beta-cholan-24-oic acid") -AnnotationAssertion(Annotation( "ChemIDplus") "5beta-cholanic acid") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChemIDplus") "(5beta)-cholan-24-oic acid") -AnnotationAssertion(Annotation( "ChemIDplus") "(5beta,17beta)-gamma-methylandrostane-17-butanoic acid") -AnnotationAssertion(Annotation( "ChemIDplus") "5beta-cholanoic acid") -AnnotationAssertion(Annotation( "ChemIDplus") "ursocholanic acid") -AnnotationAssertion( "CHEBI:36238") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "5beta-cholanic acid") -SubClassOf( ) -SubClassOf( ) - -# Class: (5beta-cholanic acids) - -AnnotationAssertion( "Members of the class of cholanic acids based on a 5beta-cholane skeleton.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion( "CHEBI:36248") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "5beta-cholanic acids") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (bile acid salt) AnnotationAssertion( "A salt of a bile acid.") @@ -26122,17 +12849,6 @@ AnnotationAssertion(rdfs:label "bil SubClassOf( ) SubClassOf( ) -# Class: (cholanic acids) - -AnnotationAssertion( "CHEBI:23166") -AnnotationAssertion( "CHEBI:23211") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion( "CHEBI:36278") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "cholanic acids") -SubClassOf( ) -SubClassOf( ) - # Class: (cyclic tetrapyrrole) AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "macrocyclic tetrapyrroles") @@ -26178,17 +12894,6 @@ AnnotationAssertion( "fermion") SubClassOf( ) -# Class: (boson) - -AnnotationAssertion( "Particle of integer spin quantum number following Bose-Einstein statistics. Bosons are named after Satyendra Nath Bose.") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "boson") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "bosons") -AnnotationAssertion( "CHEBI:36341") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "boson") -SubClassOf( ) - # Class: (subatomic particle) AnnotationAssertion( "A particle smaller than an atom.") @@ -26341,18 +13046,6 @@ AnnotationAssertion(rdfs:label "org SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (corticosteroid hormone) - -AnnotationAssertion( "Any of a class of steroid hormones that are produced in the adrenal cortex.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "adrenal cortex hormones") -AnnotationAssertion(Annotation( "ChEBI") "corticosteroid hormones") -AnnotationAssertion( "CHEBI:36699") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "corticosteroid hormone") -SubClassOf( ) -SubClassOf( ) - # Class: (phosphocholines) AnnotationAssertion( "Any compound having phosphocholine as part of its structure.") @@ -26417,55 +13110,6 @@ AnnotationAssertion(rdfs:label "far SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (17-hydroxy steroid) - -AnnotationAssertion( "A hydroxy steroid carrying a hydroxy group at position 17.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "17-hydroxy steroids") -AnnotationAssertion( "CHEBI:36838") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "17-hydroxy steroid") -SubClassOf( ) - -# Class: (11-hydroxy steroid) - -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "11-hydroxy steroids") -AnnotationAssertion( "CHEBI:36841") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "11-hydroxy steroid") -SubClassOf( ) - -# Class: (20-oxo steroid) - -AnnotationAssertion( "An oxo steroid carrying an oxo group at position 20.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "20-oxo steroids") -AnnotationAssertion( "CHEBI:36885") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "20-oxo steroid") -SubClassOf( ) - -# Class: (18-oxo steroid) - -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "18-oxo steroids") -AnnotationAssertion( "CHEBI:36887") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "18-oxo steroid") -SubClassOf( ) - -# Class: (chalcogen hydride) - -AnnotationAssertion(Annotation( "ChEBI") "chalcogen hydride") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "chalcogen hydrides") -AnnotationAssertion( "CHEBI:36902") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "chalcogen hydride") -SubClassOf( ) -SubClassOf( ) - # Class: (inorganic ion) AnnotationAssertion( "chebi_ontology") @@ -26541,32 +13185,6 @@ AnnotationAssertion(rdfs:label "org SubClassOf( ) SubClassOf( ) -# Class: (nucleotide) - -AnnotationAssertion( "A nucleotide is a nucleoside phosphate resulting from the condensation of the 3 or 5 hydroxy group of a nucleoside with phosphoric acid.") -AnnotationAssertion( "CHEBI:13215") -AnnotationAssertion( "CHEBI:13663") -AnnotationAssertion( "CHEBI:7656") -AnnotationAssertion( "KEGG:C00215") -AnnotationAssertion( "Wikipedia:Nucleotide") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Nucleotide") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "nucleotides") -AnnotationAssertion( "CHEBI:36976") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "nucleotide") -SubClassOf( ) - -# Class: (ribonucleoside 5'-phosphate) - -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "ribonucleoside 5'-phosphates") -AnnotationAssertion( "CHEBI:37015") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "ribonucleoside 5'-phosphate") -SubClassOf( ) -SubClassOf( ) - # Class: (amino-acid anion) AnnotationAssertion(Annotation( "ChEBI") "amino-acid anion") @@ -26580,84 +13198,6 @@ SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (purine ribonucleoside 5'-diphosphate) - -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "purine ribonucleoside 5'-diphosphates") -AnnotationAssertion( "CHEBI:37038") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "purine ribonucleoside 5'-diphosphate") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (purine ribonucleoside 5'-triphosphate) - -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "purine ribonucleoside 5'-triphosphates") -AnnotationAssertion( "CHEBI:37045") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "purine ribonucleoside 5'-triphosphate") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (ribonucleoside 5'-diphosphate) - -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "ribonucleoside 5'-diphosphates") -AnnotationAssertion( "CHEBI:37075") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "ribonucleoside 5'-diphosphate") -SubClassOf( ) - -# Class: (ribonucleoside 5'-triphosphate) - -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "ribonucleoside 5'-triphosphates") -AnnotationAssertion( "CHEBI:37076") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "ribonucleoside 5'-triphosphate") -SubClassOf( ) - -# Class: (adenosine 5'-phosphate) - -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "adenosine 5'-phosphates") -AnnotationAssertion( "CHEBI:37096") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "adenosine 5'-phosphate") -SubClassOf( ) - -# Class: (glucan) - -AnnotationAssertion( "A polysaccharide composed of glucose residues.") -AnnotationAssertion( "C12H22O11(C6H10O5)n") -AnnotationAssertion( "CHEBI:24255") -AnnotationAssertion( "CHEBI:5392") -AnnotationAssertion(Annotation( "ChemIDplus") "CAS:9037-91-6") -AnnotationAssertion( "KEGG:C01379") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Glucan") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "glucan") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "glucans") -AnnotationAssertion( "CHEBI:37163") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "glucan") -SubClassOf( ) - -# Class: (homopolysaccharide) - -AnnotationAssertion( "Glycans composed of a single type of monosaccharide residue. They are named by replacing the ending '-ose' of the sugar by '-an'.") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "homopolysaccharide") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "IUPAC") "homoglycan") -AnnotationAssertion(Annotation( "ChEBI") "homopolysaccharides") -AnnotationAssertion( "CHEBI:37164") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "homopolysaccharide") -SubClassOf( ) - # Class: (organic hydride) AnnotationAssertion( "chebi_ontology") @@ -26704,21 +13244,6 @@ AnnotationAssertion( "mucopolysaccharide") SubClassOf( ) -# Class: (proteoglycan) - -AnnotationAssertion( "A glycoprotein in which the carbohydrate units are polysaccharides that contain amino sugars. The protein is glycosylated by one or more (up to about 100) glycosaminoglycans.") -AnnotationAssertion( "CHEBI:26351") -AnnotationAssertion( "CHEBI:8582") -AnnotationAssertion( "KEGG:C00866") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Proteoglycan") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "proteoglycans") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion( "CHEBI:37396") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "proteoglycan") -SubClassOf( ) -SubClassOf( ) - # Class: (chondroitin sulfate) AnnotationAssertion( "Any of a class of 10--60 kDa glycosaminoglycan sulfates, widely distributed in cartilage and other mammalian connective tissues.") @@ -26831,45 +13356,6 @@ AnnotationAssertion(rdfs:label "car SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (adrenergic agonist) - -AnnotationAssertion( "An agent that selectively binds to and activates adrenergic receptors.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "adrenergic agonists") -AnnotationAssertion(Annotation( "ChEBI") "adrenergic receptor agonist") -AnnotationAssertion(Annotation( "IUPHAR") "adrenoceptor agonists") -AnnotationAssertion(Annotation( "ChEBI") "adrenomimetic") -AnnotationAssertion(Annotation( "ChEBI") "adrenomimetics") -AnnotationAssertion( "CHEBI:37886") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "adrenergic agonist") -SubClassOf( ) - -# Class: (adrenergic agent) - -AnnotationAssertion( "Any agent that acts on an adrenergic receptor or affects the life cycle of an adrenergic transmitter.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "adrenergic agents") -AnnotationAssertion(Annotation( "ChEBI") "adrenergic drug") -AnnotationAssertion(Annotation( "ChEBI") "adrenergic drugs") -AnnotationAssertion(Annotation( "ChEBI") "adrenergic neuron agents") -AnnotationAssertion(Annotation( "ChEBI") "adrenergics") -AnnotationAssertion( "CHEBI:37962") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "adrenergic agent") -SubClassOf( ) - -# Class: (anti-arrhythmia drug) - -AnnotationAssertion( "A drug used for the treatment or prevention of cardiac arrhythmias. Anti-arrhythmia drugs may affect the polarisation-repolarisation phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibres.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "anti-arrhythmia agent") -AnnotationAssertion(Annotation( "ChEBI") "antiarrhythmic agent") -AnnotationAssertion( "CHEBI:38070") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "anti-arrhythmia drug") -SubClassOf( ) - # Class: (polypyrrole) AnnotationAssertion( "A compound composed of two or more pyrrole units.") @@ -26895,100 +13381,6 @@ AnnotationAssertion(rdfs:label "org SubClassOf( ) SubClassOf( ) -# Class: (oxacycle) - -AnnotationAssertion( "Any organic heterocyclic compound containing at least one ring oxygen atom.") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:17134300") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "heterocyclic organooxygen compounds") -AnnotationAssertion(Annotation( "ChEBI") "organooxygen heterocyclic compounds") -AnnotationAssertion(Annotation( "ChEBI") "oxacycles") -AnnotationAssertion( "CHEBI:38104") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "oxacycle") -SubClassOf( ) -SubClassOf( ) - -# Class: (cardiotonic drug) - -AnnotationAssertion( "A drug that has a strengthening effect on the heart or that can increase cardiac output.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "cardiotonic drugs") -AnnotationAssertion( "CHEBI:38147") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "cardiotonic drug") -SubClassOf( ) - -# Class: (organic heteropolycyclic compound) - -AnnotationAssertion( "CHEBI:25429") -AnnotationAssertion( "CHEBI:38075") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "organic heteropolycyclic compounds") -AnnotationAssertion( "CHEBI:38166") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "organic heteropolycyclic compound") -SubClassOf( ) -SubClassOf( ) - -# Class: (monocyclic heteroarene) - -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "monocyclic heteroarenes") -AnnotationAssertion( "CHEBI:38179") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "monocyclic heteroarene") -SubClassOf( ) - -# Class: (polycyclic heteroarene) - -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "polycyclic heteroarenes") -AnnotationAssertion( "CHEBI:38180") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "polycyclic heteroarene") -SubClassOf( ) - -# Class: (cholinergic drug) - -AnnotationAssertion( "Any drug used for its actions on cholinergic systems. Included here are agonists and antagonists, drugs that affect the life cycle of acetylcholine, and drugs that affect the survival of cholinergic neurons.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "cholinergic agent") -AnnotationAssertion(Annotation( "ChEBI") "cholinergic drugs") -AnnotationAssertion(Annotation( "ChEBI") "cholinomimetic") -AnnotationAssertion( "CHEBI:38323") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "cholinergic drug") -SubClassOf( ) - -# Class: (cholinergic agonist) - -AnnotationAssertion( "Any drug that binds to and activates cholinergic receptors.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "acetylcholine agonist") -AnnotationAssertion(Annotation( "ChEBI") "acetylcholine agonists") -AnnotationAssertion(Annotation( "IUPHAR") "acetylcholine receptor agonist") -AnnotationAssertion(Annotation( "ChEBI") "cholinergic agonists") -AnnotationAssertion(Annotation( "ChEBI") "cholinomimetic") -AnnotationAssertion(Annotation( "ChEBI") "cholinomimetics") -AnnotationAssertion( "CHEBI:38324") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "cholinergic agonist") -SubClassOf( ) - -# Class: (muscarinic agonist) - -AnnotationAssertion( "Any drug that binds to and activates a muscarinic cholinergic receptor.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "muscarinic acetylcholine receptor agonist") -AnnotationAssertion(Annotation( "ChEBI") "muscarinic agonists") -AnnotationAssertion(Annotation( "ChEBI") "muscarinic cholinergic agonist") -AnnotationAssertion(Annotation( "ChEBI") "muscarinic cholinergic agonists") -AnnotationAssertion( "CHEBI:38325") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "muscarinic agonist") -SubClassOf( ) - # Class: (simple protein) AnnotationAssertion( "chebi_ontology") @@ -26998,17 +13390,6 @@ AnnotationAssertion( "simple protein") SubClassOf( ) -# Class: (aminoalkylindole) - -AnnotationAssertion( "CHEBI:22503") -AnnotationAssertion( "CHEBI:24792") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "aminoalkylindoles") -AnnotationAssertion( "CHEBI:38631") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "aminoalkylindole") -SubClassOf( ) - # Class: (organic sodium salt) AnnotationAssertion(Annotation( "ChEBI") "organic sodium salt") @@ -27047,58 +13428,6 @@ AnnotationAssertion( "anaesthetic") SubClassOf( ) -# Class: (corticotropin) - -AnnotationAssertion( "A polypeptide hormone produced and secreted by the pituitary gland comprising 39 amino acid residues coupled in a linear sequence. The N-terminal 24-amino acid segment is identical in all species and contains the adrenocorticotrophic activity. Corticotropin stimulates the cortex of the adrenal gland and boosts the synthesis of corticosteroids, mainly glucocorticoids but also sex steroids (androgens). It is used in the treatment of certain neurological disorders such as infantile spasms and multiple sclerosis, and diagnostically to investigate adrenocortical insufficiency.") -AnnotationAssertion( "0") -AnnotationAssertion( "C207H308N56O58S") -AnnotationAssertion( "InChI=1S/C207H308N56O58S/c1-108(2)89-140(186(302)240-135(69-74-163(279)280)182(298)254-149(204(320)321)94-117-43-20-15-21-44-117)250-193(309)152-54-35-86-262(152)202(318)147(92-116-41-18-14-19-42-116)252-171(287)114(11)230-175(291)132(66-71-160(273)274)234-170(286)113(10)231-191(307)150(105-265)255-183(299)136(70-75-164(281)282)241-190(306)146(98-165(283)284)249-180(296)133(67-72-161(275)276)235-169(285)112(9)229-157(270)101-225-174(290)145(97-156(213)269)251-194(310)153-55-36-87-263(153)203(319)148(93-119-60-64-123(268)65-61-119)253-199(315)167(110(5)6)257-185(301)129(49-26-30-79-210)243-198(314)168(111(7)8)259-196(312)155-57-38-85-261(155)201(317)139(53-34-83-223-207(218)219)244-178(294)130(51-32-81-221-205(214)215)237-177(293)128(48-25-29-78-209)236-176(292)127(47-24-28-77-208)232-158(271)103-227-197(313)166(109(3)4)258-195(311)154-56-37-84-260(154)200(316)138(50-27-31-80-211)233-159(272)102-226-173(289)143(95-120-99-224-126-46-23-22-45-124(120)126)247-179(295)131(52-33-82-222-206(216)217)238-187(303)142(90-115-39-16-13-17-40-115)246-189(305)144(96-121-100-220-107-228-121)248-181(297)134(68-73-162(277)278)239-184(300)137(76-88-322-12)242-192(308)151(106-266)256-188(304)141(245-172(288)125(212)104-264)91-118-58-62-122(267)63-59-118/h13-23,39-46,58-65,99-100,107-114,125,127-155,166-168,224,264-268H,24-38,47-57,66-98,101-106,208-212H2,1-12H3,(H2,213,269)(H,220,228)(H,225,290)(H,226,289)(H,227,313)(H,229,270)(H,230,291)(H,231,307)(H,232,271)(H,233,272)(H,234,286)(H,235,285)(H,236,292)(H,237,293)(H,238,303)(H,239,300)(H,240,302)(H,241,306)(H,242,308)(H,243,314)(H,244,294)(H,245,288)(H,246,305)(H,247,295)(H,248,297)(H,249,296)(H,250,309)(H,251,310)(H,252,287)(H,253,315)(H,254,298)(H,255,299)(H,256,304)(H,257,301)(H,258,311)(H,259,312)(H,273,274)(H,275,276)(H,277,278)(H,279,280)(H,281,282)(H,283,284)(H,320,321)(H4,214,215,221)(H4,216,217,222)(H4,218,219,223)/t112-,113-,114-,125-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,144-,145-,146-,147-,148-,149-,150-,151-,152-,153-,154-,155-,166-,167-,168-/m0/s1") -AnnotationAssertion( "IDLFZVILOHSSID-OVLDLUHVSA-N") -AnnotationAssertion( "4541.06600") -AnnotationAssertion( "4538.25937") -AnnotationAssertion( "CSCC[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](N)CO)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(O)=O") -AnnotationAssertion(Annotation( "ChemIDplus") "CAS:9002-60-2") -AnnotationAssertion(Annotation( "KEGG COMPOUND") "CAS:9002-60-2") -AnnotationAssertion( "DrugBank:DB01285") -AnnotationAssertion(Annotation( "DrugCentral") "Drug_Central:4931") -AnnotationAssertion( "KEGG:C02017") -AnnotationAssertion( "KEGG:D00146") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Corticotropin") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "L-seryl-L-tyrosyl-L-seryl-L-methionyl-L-alpha-glutamyl-L-histidyl-L-phenylalanyl-L-arginyl-L-tryptophylglycyl-L-lysyl-L-prolyl-L-valylglycyl-L-lysyl-L-lysyl-L-arginyl-L-arginyl-L-prolyl-L-valyl-L-lysyl-L-valyl-L-tyrosyl-L-prolyl-L-alpha-aspartylglycyl-L-alanyl-L-alpha-glutamyl-L-alpha-aspartyl-L-alpha-glutamyl-L-seryl-L-alanyl-L-alpha-glutamyl-L-alanyl-L-phenylalanyl-L-prolyl-L-leucyl-L-alpha-glutamyl-L-phenylalanine") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "ACTH") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Adrenocorticotropic hormone") -AnnotationAssertion(Annotation( "DrugBank") "SYSMEHFRWGKPVGKKRRPVKVYPDGAEDQLAEAFPLEF") -AnnotationAssertion(Annotation( "ChemIDplus") "adrenocorticotropin") -AnnotationAssertion(Annotation( "ChemIDplus") Annotation( ) "corticotrofina") -AnnotationAssertion(Annotation( "ChemIDplus") Annotation( ) "corticotrophine") -AnnotationAssertion(Annotation( "ChemIDplus") Annotation( ) "corticotrophinum") -AnnotationAssertion(Annotation( "ChemIDplus") Annotation( ) "corticotropin") -AnnotationAssertion(Annotation( "ChemIDplus") "cortrophin") -AnnotationAssertion( "CHEBI:3892") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "corticotropin") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (indole alkaloid) - -AnnotationAssertion( "An alkaloid containing an indole skeleton.") -AnnotationAssertion( "CHEBI:24795") -AnnotationAssertion( "CHEBI:5901") -AnnotationAssertion( "KEGG:C06073") -AnnotationAssertion( "Wikipedia:Indole_alkaloid") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Indole alkaloid") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "indole alkaloids") -AnnotationAssertion( "CHEBI:38958") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "indole alkaloid") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (apolipoprotein) AnnotationAssertion( "Protein component on the surface of lipoprotein.") @@ -27218,20 +13547,6 @@ AnnotationAssertion(rdfs:label "Lew SubClassOf( ) SubClassOf( ) -# Class: (straight-chain saturated fatty acid) - -AnnotationAssertion( "Any saturated fatty acid lacking a side-chain.") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:15644336") -AnnotationAssertion(Annotation( "ChEBI") "straight-chain saturated fatty acid") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "straight-chain saturated fatty acids") -AnnotationAssertion( "CHEBI:39418") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "straight-chain saturated fatty acid") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (dihydrogenphosphate) AnnotationAssertion( "A monovalent inorganic anion that consists of phosphoric acid in which one of the three OH groups has been deprotonated.") @@ -27264,48 +13579,6 @@ SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (cyclic ketone) - -AnnotationAssertion( "KEGG:C02019") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Cyclic ketone") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "cyclic ketones") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion( "CHEBI:3992") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "cyclic ketone") -SubClassOf( ) - -# Class: ((S)-adrenaline) - -AnnotationAssertion( "The S-enantiomer of adrenaline.") -AnnotationAssertion( "0") -AnnotationAssertion( "C9H13NO3") -AnnotationAssertion( "InChI=1S/C9H13NO3/c1-10-5-9(13)6-2-3-7(11)8(12)4-6/h2-4,9-13H,5H2,1H3/t9-/m1/s1") -AnnotationAssertion( "UCTWMZQNUQWSLP-SECBINFHSA-N") -AnnotationAssertion( "183.20446") -AnnotationAssertion( "183.08954") -AnnotationAssertion( "CNC[C@@H](O)c1ccc(O)c(O)c1") -AnnotationAssertion( "CHEBI:30615") -AnnotationAssertion( "CHEBI:40743") -AnnotationAssertion(Annotation( "ChemIDplus") "Beilstein:2938799") -AnnotationAssertion(Annotation( "ChemIDplus") "CAS:150-05-0") -AnnotationAssertion( "PDBeChem:ALE") -AnnotationAssertion(Annotation( "Reaxys") "Reaxys:2938799") -AnnotationAssertion(Annotation( "UniProt") "(S)-adrenaline") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "4-[(1S)-1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChemIDplus") "(+)-3,4-dihydroxy-alpha-((methylamino)methyl)benzyl alcohol") -AnnotationAssertion(Annotation( "IUPHAR") "(+)-adrenaline") -AnnotationAssertion(Annotation( "ChEBI") "(S)-(+)-adrenaline") -AnnotationAssertion(Annotation( "ChemIDplus") "(S)-4-(1-hydroxy-2-(methylamino)ethyl)pyrocatechol") -AnnotationAssertion(Annotation( "ChemIDplus") "d-adrenaline") -AnnotationAssertion(Annotation( "ChemIDplus") "d-epinephrine") -AnnotationAssertion( "CHEBI:40751") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "(S)-adrenaline") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (carbonate) AnnotationAssertion( "-2") @@ -27334,32 +13607,6 @@ AnnotationAssertion(rdfs:label "car SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (formyl group) - -AnnotationAssertion( "0") -AnnotationAssertion( "CHO") -AnnotationAssertion( "29.01804") -AnnotationAssertion( "29.00274") -AnnotationAssertion( "[H]C(*)=O") -AnnotationAssertion( "CHEBI:24089") -AnnotationAssertion( "CHEBI:42480") -AnnotationAssertion( "PDBeChem:FOR") -AnnotationAssertion(Annotation( "PDBeChem") "FORMYL GROUP") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "aldehyde group") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "carbaldehyde") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "formyl") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "IUPAC") "-CH(O)") -AnnotationAssertion(Annotation( "IUPAC") "-CHO") -AnnotationAssertion(Annotation( "CBN") "Fo") -AnnotationAssertion(Annotation( "IUPAC") "H-CO-") -AnnotationAssertion(Annotation( "IUPAC") "methanoyl") -AnnotationAssertion( "CHEBI:42485") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "formyl group") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (hydroxy group) AnnotationAssertion( "0") @@ -27421,32 +13668,6 @@ SubClassOf( ObjectSomeValuesFrom( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (ADP(3-)) - -AnnotationAssertion( "A nucleoside 5'-diphosphate(3-) arising from deprotonation of all three diphosphate OH groups of adenosine 5'-diphosphate (ADP); major species present at pH 7.3.") -AnnotationAssertion( "-3") -AnnotationAssertion( "C10H12N5O10P2") -AnnotationAssertion( "InChI=1S/C10H15N5O10P2/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(24-10)1-23-27(21,22)25-26(18,19)20/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H2,11,12,13)(H2,18,19,20)/p-3/t4-,6-,7-,10-/m1/s1") -AnnotationAssertion( "XTWYTFMLZFPYCI-KQYNXXCUSA-K") -AnnotationAssertion( "424.17730") -AnnotationAssertion( "424.00759") -AnnotationAssertion( "Nc1ncnc2n(cnc12)[C@@H]1O[C@H](COP([O-])(=O)OP([O-])([O-])=O)[C@@H](O)[C@H]1O") -AnnotationAssertion(Annotation( "Beilstein") "Beilstein:3783669") -AnnotationAssertion(Annotation( "Gmelin") "Gmelin:341336") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "adenosine 5'-diphosphate") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "5'-O-[(phosphonatooxy)phosphinato]adenosine") -AnnotationAssertion(Annotation( "UniProt") "ADP") -AnnotationAssertion(Annotation( "ChEBI") "ADP trianion") -AnnotationAssertion( "CHEBI:456216") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "ADP(3-)") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (hydrogensulfate) AnnotationAssertion( "-1") @@ -27565,146 +13786,6 @@ AnnotationAssertion( "carboxy group") SubClassOf( ) -# Class: (L-ribose) - -AnnotationAssertion( "A ribose in which the chiral carbon atom furthest away from the aldehyde group (C4') has the same configuration as in L-glyceraldehyde.") -AnnotationAssertion( "0") -AnnotationAssertion( "C5H10O5") -AnnotationAssertion( "150.130") -AnnotationAssertion( "150.05282") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "L-ribo-pentose") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "L-ribose") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "JCBN") "L-Rib") -AnnotationAssertion( "CHEBI:46997") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "L-ribose") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (ribofuranose) - -AnnotationAssertion( "A cyclic ribose having a 5-membered tetrahydrofuran ring; the predominant (C3'-endo) form of the two cyclic structures (the other is the \"C2'-endo\" form, having a 6-membered ring) adopted by ribose in aqueous solution.") -AnnotationAssertion( "0") -AnnotationAssertion( "C5H10O5") -AnnotationAssertion( "150.12990") -AnnotationAssertion( "150.05282") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "ribofuranose") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "IUPAC") "rel-(3R,4S,5R)-5-(hydroxymethyl)tetrahydrofuran-2,3,4-triol") -AnnotationAssertion( "CHEBI:46998") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "ribofuranose") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (D-ribofuranose) - -AnnotationAssertion( "A ribofuranose having D-configuration.") -AnnotationAssertion( "0") -AnnotationAssertion( "C5H10O5") -AnnotationAssertion( "InChI=1S/C5H10O5/c6-1-2-3(7)4(8)5(9)10-2/h2-9H,1H2/t2-,3-,4-,5?/m1/s1") -AnnotationAssertion( "HMFHBZSHGGEWLO-SOOFDHNKSA-N") -AnnotationAssertion( "150.12990") -AnnotationAssertion( "150.05282") -AnnotationAssertion( "OC[C@H]1OC(O)[C@H](O)[C@@H]1O") -AnnotationAssertion( "CHEBI:4233") -AnnotationAssertion( "CHEBI:46999") -AnnotationAssertion(Annotation( "Beilstein") "Beilstein:1904878") -AnnotationAssertion(Annotation( "KEGG COMPOUND") "CAS:50-69-1") -AnnotationAssertion(Annotation( "ChemIDplus") "CAS:613-83-2") -AnnotationAssertion( "GlyGen:G31080DL") -AnnotationAssertion( "GlyTouCan:G31080DL") -AnnotationAssertion(Annotation( "Gmelin") "Gmelin:364108") -AnnotationAssertion( "KEGG:C00121") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:9506998") -AnnotationAssertion( "Patent:US2152662") -AnnotationAssertion(Annotation( "Reaxys") "Reaxys:1904878") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "D-ribofuranose") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "IUPAC") "(3R,4S,5R)-5-(hydroxymethyl)tetrahydrofuran-2,3,4-triol") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "D-Ribose") -AnnotationAssertion(Annotation( "UniProt") "D-ribose") -AnnotationAssertion(Annotation( "GlyTouCan") "WURCS=2.0/1,1,0/[a222h-1x_1-4]/1/") -AnnotationAssertion(Annotation( "ChemIDplus") "ribose") -AnnotationAssertion( "CHEBI:47013") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "D-ribofuranose") -SubClassOf( ) -SubClassOf( ) - -# Class: (tetrahydrofuranol) - -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "tetrahydrofuranols") -AnnotationAssertion( "CHEBI:47017") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "tetrahydrofuranol") -SubClassOf( ) - -# Class: (dihydroxytetrahydrofuran) - -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "dihydroxytetrahydrofurans") -AnnotationAssertion( "CHEBI:47019") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "dihydroxytetrahydrofuran") -SubClassOf( ) - -# Class: (acetate ester) - -AnnotationAssertion( "Any carboxylic ester where the carboxylic acid component is acetic acid.") -AnnotationAssertion( "0") -AnnotationAssertion( "C2H3O2R") -AnnotationAssertion( "59.04400") -AnnotationAssertion( "59.01330") -AnnotationAssertion( "CC(=O)O[*]") -AnnotationAssertion( "CHEBI:13244") -AnnotationAssertion( "CHEBI:13799") -AnnotationAssertion( "CHEBI:22189") -AnnotationAssertion( "CHEBI:2406") -AnnotationAssertion( "KEGG:C01883") -AnnotationAssertion( "Wikipedia:Acetate#Esters") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Acetic ester") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Acetyl ester") -AnnotationAssertion(Annotation( "ChEBI") "acetate") -AnnotationAssertion(Annotation( "ChEBI") "acetate esters") -AnnotationAssertion(Annotation( "ChEBI") "acetates") -AnnotationAssertion(Annotation( "ChEBI") "acetyl esters") -AnnotationAssertion(Annotation( "UniProt") "an acetyl ester") -AnnotationAssertion( "CHEBI:47622") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "acetate ester") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (3-oxo steroid) - -AnnotationAssertion( "Any oxo steroid where an oxo substituent is located at position 3.") -AnnotationAssertion( "0") -AnnotationAssertion( "C19H29OR") -AnnotationAssertion( "273.434") -AnnotationAssertion( "273.22184") -AnnotationAssertion( "C12C(C3C(C(CC3)*)(C)CC1)CCC4C2(CCC(C4)=O)C") -AnnotationAssertion( "CHEBI:13607") -AnnotationAssertion( "CHEBI:1653") -AnnotationAssertion( "CHEBI:20182") -AnnotationAssertion( "CHEBI:71186") -AnnotationAssertion( "KEGG:C01876") -AnnotationAssertion( "MetaCyc:3-Oxosteroids") -AnnotationAssertion(Annotation( "SUBMITTER") "PMID:9811880") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "3-Oxosteroid") -AnnotationAssertion(Annotation( "ChEBI") "3-oxo steroids") -AnnotationAssertion(Annotation( "ChEBI") "3-oxosteroids") -AnnotationAssertion(Annotation( "UniProt") "a 3-oxosteroid") -AnnotationAssertion( "CHEBI:47788") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "3-oxo steroid") -SubClassOf( ) -SubClassOf( ) - # Class: (cyclic polypyrrole) AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "macrocyclic polypyrroles") @@ -27716,44 +13797,6 @@ AnnotationAssertion( "cyclic polypyrrole") SubClassOf( ) -# Class: (steroid acid) - -AnnotationAssertion( "Any steroid substituted by at least one carboxy group.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "steroid acids") -AnnotationAssertion( "CHEBI:47891") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "steroid acid") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (3-oxo-Delta(4) steroid) - -AnnotationAssertion( "A 3-oxo steroid conjugated to a C=C double bond at the alpha,beta position.") -AnnotationAssertion( "0") -AnnotationAssertion( "C19H27OR") -AnnotationAssertion( "271.418") -AnnotationAssertion( "271.20619") -AnnotationAssertion( "C12C(C3C(C(CC3)*)(C)CC1)CCC=4C2(CCC(C4)=O)C") -AnnotationAssertion( "CHEBI:13604") -AnnotationAssertion( "CHEBI:1626") -AnnotationAssertion( "CHEBI:20157") -AnnotationAssertion( "KEGG:C00619") -AnnotationAssertion( "MetaCyc:3-Oxo-Delta-4-Steroids") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "3-Oxo-delta4-steroid") -AnnotationAssertion(Annotation( "ChEBI") "3-oxo Delta(4)-steroid") -AnnotationAssertion(Annotation( "ChEBI") "3-oxo Delta(4)-steroids") -AnnotationAssertion(Annotation( "ChEBI") "3-oxo-Delta(4) steroids") -AnnotationAssertion(Annotation( "UniProt") "a 3-oxo-Delta(4)-steroid") -AnnotationAssertion( "CHEBI:47909") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "3-oxo-Delta(4) steroid") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (sulfur oxide) AnnotationAssertion( "chebi_ontology") @@ -27766,97 +13809,6 @@ AnnotationAssertion(rdfs:label "sul SubClassOf( ) SubClassOf( ) -# Class: (polar solvent) - -AnnotationAssertion( "A solvent that is composed of polar molecules. Polar solvents can dissolve ionic compounds or ionisable covalent compounds.") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "polar solvent") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "polar solvents") -AnnotationAssertion( "CHEBI:48354") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "polar solvent") -SubClassOf( ) - -# Class: (protic solvent) - -AnnotationAssertion( "A polar solvent that is capable of acting as a hydron (proton) donor.") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "protogenic solvent") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion( "CHEBI:48356") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "protic solvent") -SubClassOf( ) -SubClassOf( ) - -# Class: (protophilic solvent) - -AnnotationAssertion( "Solvent that is capable of acting as a hydron (proton) acceptor.") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "protophilic solvent") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "HBA solvent") -AnnotationAssertion(Annotation( "ChEBI") "hydrogen bond acceptor solvent") -AnnotationAssertion( "CHEBI:48359") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "protophilic solvent") -SubClassOf( ) -SubClassOf( ) - -# Class: (amphiprotic solvent) - -AnnotationAssertion( "Self-ionizing solvent possessing both characteristics of Bronsted acids and bases.") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "amphiprotic solvent") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion( "CHEBI:48360") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "amphiprotic solvent") -SubClassOf( ) -SubClassOf( ) - -# Class: (alpha-adrenergic drug) - -AnnotationAssertion( "Any drug that acts on an alpha-adrenergic receptor.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "alpha-adrenergic drugs") -AnnotationAssertion( "CHEBI:48539") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "alpha-adrenergic drug") -SubClassOf( ) - -# Class: (beta-adrenergic drug) - -AnnotationAssertion( "Any of the drugs that act on beta-adrenergic receptors.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "beta-adrenergic drugs") -AnnotationAssertion( "CHEBI:48540") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "beta-adrenergic drug") -SubClassOf( ) - -# Class: (dopaminergic agent) - -AnnotationAssertion( "A drug used for its effects on dopamine receptors, on the life cycle of dopamine, or on the survival of dopaminergic neurons.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "dopamine agent") -AnnotationAssertion(Annotation( "ChEBI") "dopamine agents") -AnnotationAssertion(Annotation( "ChEBI") "dopamine drug") -AnnotationAssertion(Annotation( "ChEBI") "dopamine drugs") -AnnotationAssertion(Annotation( "ChEBI") "dopaminergic agents") -AnnotationAssertion( "CHEBI:48560") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "dopaminergic agent") -SubClassOf( ) - -# Class: (radical scavenger) - -AnnotationAssertion( "A role played by a substance that can react readily with, and thereby eliminate, radicals.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "free radical scavengers") -AnnotationAssertion(Annotation( "ChEBI") "free-radical scavenger") -AnnotationAssertion( "CHEBI:48578") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "radical scavenger") -SubClassOf( ) - # Class: (agonist) AnnotationAssertion( "Substance which binds to cell receptors normally responding to naturally occurring substances and which produces a response of its own.") @@ -27883,17 +13835,6 @@ AnnotationAssertion( "antagonist") SubClassOf( ) -# Class: (contraceptive drug) - -AnnotationAssertion( "A chemical substance that prevents or reduces the probability of conception.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "contraceptive agent") -AnnotationAssertion(Annotation( "ChEBI") "contraceptive drugs") -AnnotationAssertion( "CHEBI:49323") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "contraceptive drug") -SubClassOf( ) - # Class: (hydrogen atom) AnnotationAssertion( "0") @@ -27935,49 +13876,6 @@ SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (sex hormone) - -AnnotationAssertion( "Any hormone that is responsible for controlling sexual characteristics and reproductive function.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "Geschlechtshormon") -AnnotationAssertion(Annotation( "ChEBI") "Geschlechtshormone") -AnnotationAssertion(Annotation( "ChEBI") "Sexualhormon") -AnnotationAssertion(Annotation( "ChEBI") "Sexualhormone") -AnnotationAssertion(Annotation( "ChEBI") "hormone sexuelle") -AnnotationAssertion(Annotation( "ChEBI") "hormones sexuelles") -AnnotationAssertion(Annotation( "ChEBI") "sex hormones") -AnnotationAssertion( "CHEBI:50112") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "sex hormone") -SubClassOf( ) - -# Class: (androgen) - -AnnotationAssertion( "A sex hormone that stimulates or controls the development and maintenance of masculine characteristics in vertebrates by binding to androgen receptors.") -AnnotationAssertion(Annotation( "ChEBI") "Androgen") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "Androgene") -AnnotationAssertion(Annotation( "ChEBI") "androgene") -AnnotationAssertion(Annotation( "ChEBI") "androgenes") -AnnotationAssertion(Annotation( "ChEBI") "androgeno") -AnnotationAssertion(Annotation( "ChEBI") "androgenos") -AnnotationAssertion(Annotation( "ChEBI") "androgens") -AnnotationAssertion( "CHEBI:50113") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "androgen") -SubClassOf( ) - -# Class: (steroid acid anion) - -AnnotationAssertion( "Any anion formed by loss of a proton from a steroid acid.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "steroid acid anions") -AnnotationAssertion( "CHEBI:50160") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "steroid acid anion") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (provitamin) AnnotationAssertion( "A substance that can be converted into a vitamin by animal tissues.") @@ -27989,47 +13887,6 @@ AnnotationAssertion( "provitamin") SubClassOf( ) -# Class: (protective agent) - -AnnotationAssertion( "Synthetic or natural substance which is given to prevent a disease or disorder or are used in the process of treating a disease or injury due to a poisonous agent.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "chemoprotectant") -AnnotationAssertion(Annotation( "ChEBI") "chemoprotectants") -AnnotationAssertion(Annotation( "ChEBI") "chemoprotective agent") -AnnotationAssertion(Annotation( "ChEBI") "chemoprotective agents") -AnnotationAssertion(Annotation( "ChEBI") "protective agents") -AnnotationAssertion( "CHEBI:50267") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "protective agent") -SubClassOf( ) - -# Class: (canonical nucleotide residue) - -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "canonical nucleotide residues") -AnnotationAssertion( "CHEBI:50297") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "canonical nucleotide residue") -SubClassOf( ) - -# Class: (canonical deoxyribonucleotide residue) - -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "canonical deoxyribonucleotide residues") -AnnotationAssertion( "CHEBI:50298") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "canonical deoxyribonucleotide residue") -SubClassOf( ) - -# Class: (canonical ribonucleotide residue) - -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "canonical ribonucleotide residues") -AnnotationAssertion( "CHEBI:50299") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "canonical ribonucleotide residue") -SubClassOf( ) - # Class: (onium compound) AnnotationAssertion( "chebi_ontology") @@ -28051,83 +13908,6 @@ AnnotationAssertion( "onium cation") SubClassOf( ) -# Class: (nucleotide residue) - -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "nucleotide residues") -AnnotationAssertion( "CHEBI:50319") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "nucleotide residue") -SubClassOf( ) - -# Class: (nucleoside residue) - -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "nucleoside residues") -AnnotationAssertion( "CHEBI:50320") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "nucleoside residue") -SubClassOf( ) - -# Class: (proteinogenic amino-acid side-chain group) - -AnnotationAssertion( "A univalent organyl group obtained by cleaving the bond from C-2 to the side chain of a proteinogenic amino-acid.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "canonical amino-acid side-chain") -AnnotationAssertion(Annotation( "ChEBI") "canonical amino-acid side-chains") -AnnotationAssertion(Annotation( "ChEBI") "proteinogenic amino-acid side-chain") -AnnotationAssertion(Annotation( "ChEBI") "proteinogenic amino-acid side-chain groups") -AnnotationAssertion(Annotation( "ChEBI") "proteinogenic amino-acid side-chains") -AnnotationAssertion( "CHEBI:50325") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "proteinogenic amino-acid side-chain group") -SubClassOf( ) - -# Class: (2-carboxyethyl group) - -AnnotationAssertion( "0") -AnnotationAssertion( "C3H5O2") -AnnotationAssertion( "73.07060") -AnnotationAssertion( "73.02895") -AnnotationAssertion( "C(CC(=O)O)*") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "2-carboxyethyl") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "glutamic acid side-chain") -AnnotationAssertion( "CHEBI:50329") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "2-carboxyethyl group") -SubClassOf( ) - -# Class: (androstanoid) - -AnnotationAssertion( "Any steroid based on an androstane skeleton and its derivatives.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "androstanoids") -AnnotationAssertion( "CHEBI:50402") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "androstanoid") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (mydriatic agent) - -AnnotationAssertion( "Agent that dilates the pupil. Used in eye diseases and to facilitate eye examination. It may be either a sympathomimetic or parasympatholytic. The latter cause cycloplegia or paralysis of accommodation at high doses and may precipitate glaucoma.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "mydriatics") -AnnotationAssertion( "CHEBI:50513") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "mydriatic agent") -SubClassOf( ) - -# Class: (vasoconstrictor agent) - -AnnotationAssertion( "Drug used to cause constriction of the blood vessels.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion( "CHEBI:50514") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "vasoconstrictor agent") -SubClassOf( ) - # Class: (bone density conservation agent) AnnotationAssertion( "An agent that inhibits bone resorption and/or favor bone mineralization and bone regeneration. Used to heal bone fractures and to treat bone diseases such as osteopenia and osteoporosis.") @@ -28158,87 +13938,6 @@ AnnotationAssertion( "bone density conservation agent") SubClassOf( ) -# Class: (reproductive control drug) - -AnnotationAssertion( "A substance used either in the prevention or facilitation of pregnancy.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "reproductive control agent") -AnnotationAssertion(Annotation( "ChEBI") "reproductive control drugs") -AnnotationAssertion( "CHEBI:50689") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "reproductive control drug") -SubClassOf( ) - -# Class: (nutraceutical) - -AnnotationAssertion( "A product in capsule, tablet or liquid form that provide essential nutrients, such as a vitamin, an essential mineral, a protein, an herb, or similar nutritional substance.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "Dietary Supplement") -AnnotationAssertion(Annotation( "ChEBI") "Food Supplementation") -AnnotationAssertion(Annotation( "ChEBI") "Nutritional supplement") -AnnotationAssertion( "CHEBI:50733") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "nutraceutical") -SubClassOf( ) - -# Class: (progestogen) - -AnnotationAssertion( "A compound that interacts with progesterone receptors in target tissues to bring about effects similar to those of progesterone.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "gestagen") -AnnotationAssertion(Annotation( "ChEBI") "gestagens") -AnnotationAssertion(Annotation( "ChEBI") "progestagen") -AnnotationAssertion(Annotation( "ChEBI") "progestagens") -AnnotationAssertion(Annotation( "ChEBI") "progestogens") -AnnotationAssertion( "CHEBI:50745") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "progestogen") -SubClassOf( ) - -# Class: (immunomodulator) - -AnnotationAssertion( "Biologically active substance whose activity affects or plays a role in the functioning of the immune system.") -AnnotationAssertion( "Wikipedia:Immunotherapy") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "Biomodulator") -AnnotationAssertion(Annotation( "ChEBI") "Immune factor") -AnnotationAssertion(Annotation( "ChEBI") "Immunologic factor") -AnnotationAssertion(Annotation( "ChEBI") "Immunological factor") -AnnotationAssertion(Annotation( "ChEBI") "immunomodulators") -AnnotationAssertion( "CHEBI:50846") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "immunomodulator") -SubClassOf( ) -SubClassOf( ) - -# Class: (immunological adjuvant) - -AnnotationAssertion( "A substance that augments, stimulates, activates, potentiates, or modulates the immune response at either the cellular or humoral level. A classical agent (Freund's adjuvant, BCG, Corynebacterium parvum, et al.) contains bacterial antigens. It could also be endogenous (e.g., histamine, interferon, transfer factor, tuftsin, interleukin-1). Its mode of action is either non-specific, resulting in increased immune responsiveness to a wide variety of antigens, or antigen-specific, i.e., affecting a restricted type of immune response to a narrow group of antigens. The therapeutic efficacy is related to its antigen-specific immunoadjuvanticity.") -AnnotationAssertion( "Wikipedia:Immunologic_adjuvant") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "Immunoactivator") -AnnotationAssertion(Annotation( "ChEBI") "Immunoadjuvant") -AnnotationAssertion(Annotation( "ChEBI") "Immunologic adjuvant") -AnnotationAssertion(Annotation( "ChEBI") "Immunopotentiator") -AnnotationAssertion(Annotation( "ChEBI") "Immunostimulant") -AnnotationAssertion( "CHEBI:50847") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "immunological adjuvant") -SubClassOf( ) -SubClassOf( ) - -# Class: (corticosteroid) - -AnnotationAssertion( "A natural or synthetic analogue of the hormones secreted by the adrenal gland.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "corticoides") -AnnotationAssertion(Annotation( "ChEBI") "corticosteroides") -AnnotationAssertion(Annotation( "ChEBI") "corticosteroids") -AnnotationAssertion( "CHEBI:50858") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "corticosteroid") -SubClassOf( ) - # Class: (organic molecular entity) AnnotationAssertion( "Any molecular entity that contains carbon.") @@ -28305,38 +14004,6 @@ AnnotationAssertion( "non-covalently-bound molecular entity") SubClassOf( ) -# Class: (primary amino compound) - -AnnotationAssertion( "A compound formally derived from ammonia by replacing one hydrogen atom by an organyl group.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "primary amino compounds") -AnnotationAssertion( "CHEBI:50994") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "primary amino compound") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (hormone agonist) - -AnnotationAssertion( "A chemical substance which binds to specific hormone receptors activating the function of the endocrine glands, the biosynthesis of their secreted hormones, or the action of hormones upon their specific sites.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion( "CHEBI:51060") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "hormone agonist") -SubClassOf( ) -SubClassOf( ) - -# Class: (hormone receptor modulator) - -AnnotationAssertion( "A drug that modulates the function of the endocrine glands, the biosynthesis of their secreted hormones, or the action of hormones upon their specific sites.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "hormone receptor modulators") -AnnotationAssertion( "CHEBI:51061") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "hormone receptor modulator") -SubClassOf( ) -SubClassOf( ) - # Class: (chemical role) AnnotationAssertion( "A role played by the molecular entity or part thereof within a chemical context.") @@ -28397,33 +14064,6 @@ AnnotationAssertion( "organic univalent group") SubClassOf( ) -# Class: (enone) - -AnnotationAssertion( "An alpha,beta-unsaturated ketone of general formula R(1)R(2)C=CR(3)-C(=O)R(4) (R(4) =/= H) in which the C=O function is conjugated to a C=C double bond at the alpha,beta position.") -AnnotationAssertion( "0") -AnnotationAssertion( "C3OR4") -AnnotationAssertion( "52.03150") -AnnotationAssertion( "51.99491") -AnnotationAssertion( "[*]\\C([*])=C(\\[*])C([*])=O") -AnnotationAssertion( "Wikipedia:Enone") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "enones") -AnnotationAssertion( "CHEBI:51689") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "enone") -SubClassOf( ) -SubClassOf( ) - -# Class: (alpha,beta-unsaturated ketone) - -AnnotationAssertion( "A ketone of general formula R(1)R(2)C=CR(3)-C(=O)R(4) (R(4) =/= H) or R(1)C#C-C(=O)R(2) (R(2) =/= H) in which the ketonic C=O function is conjugated to an unsaturated C-C bond at the alpha,beta position.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "alpha,beta-unsaturated ketones") -AnnotationAssertion( "CHEBI:51721") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "alpha,beta-unsaturated ketone") -SubClassOf( ) - # Class: (organic polycyclic compound) AnnotationAssertion( "chebi_ontology") @@ -28517,26 +14157,6 @@ AnnotationAssertion( "hydroxylapatite") SubClassOf( ) -# Class: (oxyketone) - -AnnotationAssertion( "A compound with the general formula R2C=O (R=/=H) where one or more of the R groups contains an oxy (-O-) group.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "oxyketones") -AnnotationAssertion( "CHEBI:52395") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "oxyketone") -SubClassOf( ) - -# Class: (alpha-oxyketone) - -AnnotationAssertion( "An oxyketone with the general formula R2C(=O) (R=/=H) where one or more of the R groups contains an oxy (-O-) group and the oxy and carbonyl groups are bonded to the same carbon atom.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "alpha-oxyketones") -AnnotationAssertion( "CHEBI:52396") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "alpha-oxyketone") -SubClassOf( ) - # Class: (galactolipid) AnnotationAssertion( "A glycolipid and which the glyco component is specified as galactosyl.") @@ -28546,26 +14166,6 @@ AnnotationAssertion( "galactolipid") SubClassOf( ) -# Class: (inorganic hydroxy compound) - -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "inorganic hydroxides") -AnnotationAssertion( "CHEBI:52625") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "inorganic hydroxy compound") -SubClassOf( ) -SubClassOf( ) - -# Class: (cyclic organic group) - -AnnotationAssertion( "An organic group that consists of a closed ring. It may be a substituent or a skeleton.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "cyclic organic groups") -AnnotationAssertion( "CHEBI:52845") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "cyclic organic group") -SubClassOf( ) - # Class: (epitope) AnnotationAssertion( "The biological role played by a material entity when bound by a receptor of the adaptive immune system. Specific site on an antigen to which an antibody binds.") @@ -28601,53 +14201,6 @@ AnnotationAssertion( "ionic macromolecule") SubClassOf( ) -# Class: (glucagon) - -AnnotationAssertion( "A 29-amino acid peptide hormone consisting of His, Ser, Gln, Gly, Thr, Phe, Thr, Ser, Asp, Tyr, Ser, Lys, Tyr, Leu, Asp, Ser, Arg, Arg, Ala, Gln, Asp, Phe, Val, Gln, Trp, Leu, Met, Asn and Thr residues joined in sequence.") -AnnotationAssertion( "0") -AnnotationAssertion( "C153H225N43O49S") -AnnotationAssertion( "InChI=1S/C153H225N43O49S/c1-72(2)52-97(133(226)176-96(47-51-246-11)132(225)184-104(60-115(159)209)143(236)196-123(78(10)203)151(244)245)179-137(230)103(58-83-64-167-89-29-19-18-28-87(83)89)183-131(224)95(43-46-114(158)208)177-148(241)120(74(5)6)194-141(234)101(54-79-24-14-12-15-25-79)182-138(231)105(61-117(211)212)185-130(223)94(42-45-113(157)207)171-124(217)75(7)170-127(220)91(31-22-49-165-152(160)161)172-128(221)92(32-23-50-166-153(162)163)174-146(239)110(69-199)191-140(233)107(63-119(215)216)186-134(227)98(53-73(3)4)178-135(228)99(56-81-33-37-85(204)38-34-81)180-129(222)90(30-20-21-48-154)173-145(238)109(68-198)190-136(229)100(57-82-35-39-86(205)40-36-82)181-139(232)106(62-118(213)214)187-147(240)111(70-200)192-150(243)122(77(9)202)195-142(235)102(55-80-26-16-13-17-27-80)188-149(242)121(76(8)201)193-116(210)66-168-126(219)93(41-44-112(156)206)175-144(237)108(67-197)189-125(218)88(155)59-84-65-164-71-169-84/h12-19,24-29,33-40,64-65,71-78,88,90-111,120-123,167,197-205H,20-23,30-32,41-63,66-70,154-155H2,1-11H3,(H2,156,206)(H2,157,207)(H2,158,208)(H2,159,209)(H,164,169)(H,168,219)(H,170,220)(H,171,217)(H,172,221)(H,173,238)(H,174,239)(H,175,237)(H,176,226)(H,177,241)(H,178,228)(H,179,230)(H,180,222)(H,181,232)(H,182,231)(H,183,224)(H,184,225)(H,185,223)(H,186,227)(H,187,240)(H,188,242)(H,189,218)(H,190,229)(H,191,233)(H,192,243)(H,193,210)(H,194,234)(H,195,235)(H,196,236)(H,211,212)(H,213,214)(H,215,216)(H,244,245)(H4,160,161,165)(H4,162,163,166)/t75-,76+,77+,78+,88-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,120-,121-,122-,123-/m0/s1") -AnnotationAssertion( "MASNOZXLGMXCHN-ZLPAWPGGSA-N") -AnnotationAssertion( "3482.74700") -AnnotationAssertion( "3480.61570") -AnnotationAssertion( "CSCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CO)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc1cnc[nH]1)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(O)=O") -AnnotationAssertion(Annotation( "ChemIDplus") "CAS:16941-32-5") -AnnotationAssertion(Annotation( "ChemIDplus") "CAS:9007-92-5") -AnnotationAssertion(Annotation( "KEGG COMPOUND") "CAS:9007-92-5") -AnnotationAssertion( "DrugBank:DB00040") -AnnotationAssertion(Annotation( "DrugCentral") "Drug_Central:2994") -AnnotationAssertion( "KEGG:C01501") -AnnotationAssertion( "KEGG:D00116") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:21940356") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:22014161") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:22154917") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:22166985") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:22167521") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:22214853") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:22227186") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:22286080") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:22294753") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:22318544") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:22334714") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:22399501") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:22438981") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:22454291") -AnnotationAssertion(Annotation( "Reaxys") "Reaxys:13191924") -AnnotationAssertion( "Wikipedia:Glucagon") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Glucagon") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "L-histidyl-L-seryl-L-glutaminylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-alpha-aspartyl-L-tyrosyl-L-seryl-L-lysyl-L-tyrosyl-L-leucyl-L-alpha-aspartyl-L-seryl-L-arginyl-L-arginyl-L-alanyl-L-glutaminyl-L-alpha-aspartyl-L-phenylalanyl-L-valyl-L-glutaminyl-L-tryptophyl-L-leucyl-L-methionyl-L-asparaginyl-L-threonine") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChemIDplus") "Glucagone") -AnnotationAssertion(Annotation( "ChEBI") "HSQGTFTSDYSKYLDSRRAQDFVQWLMNT") -AnnotationAssertion(Annotation( "ChEBI") "His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr") -AnnotationAssertion(Annotation( "ChemIDplus") "His-ser-glu(nh2)-gly-thr-phe-thr-ser-asp-tyr-ser-lys-tyr-leu-asp-ser-arg-arg-ala-glu(NH2)-asp-phe-val-glu(NH2)-trp-leu-met-asp(NH2)-thr") -AnnotationAssertion(Annotation( "ChemIDplus") Annotation( ) "glucagon") -AnnotationAssertion(Annotation( "ChemIDplus") Annotation( ) "glucagonum") -AnnotationAssertion( "CHEBI:5391") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "glucagon") -SubClassOf( ) - # Class: (heterocyclic compound) AnnotationAssertion( "A cyclic compound having as ring members atoms of at least two different elements.") @@ -28662,29 +14215,6 @@ AnnotationAssertion( "heterocyclic compound") SubClassOf( ) -# Class: (ATP(3-)) - -AnnotationAssertion( "A ribonucleoside triphosphate oxoanion that is the trianion of adenosine 5'-triphosphate arising from deprotonation of three of the four free triphosphate OH groups.") -AnnotationAssertion( "-3") -AnnotationAssertion( "C10H13N5O13P3") -AnnotationAssertion( "InChI=1S/C10H16N5O13P3/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20)/p-3/t4-,6-,7-,10-/m1/s1") -AnnotationAssertion( "ZKHQWZAMYRWXGA-KQYNXXCUSA-K") -AnnotationAssertion( "504.15720") -AnnotationAssertion( "503.97392") -AnnotationAssertion( "Nc1ncnc2n(cnc12)[C@@H]1O[C@H](COP([O-])(=O)OP([O-])(=O)OP(O)([O-])=O)[C@@H](O)[C@H]1O") -AnnotationAssertion(Annotation( "Beilstein") "Beilstein:9535056") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion( "CHEBI:57299") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "ATP(3-)") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (chondroitin D-glucuronate anion) AnnotationAssertion( "Anionic form of chondroitin D-glucuronate arising from deprotonation of the carboxylic acid groups of the repeating units; major species at pH 7.3.") @@ -28698,70 +14228,6 @@ AnnotationAssertion(rdfs:label "cho SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (nucleoside 5'-phosphate dianion) - -AnnotationAssertion( "The conjugate base of a nucleoside 5'-phosphate.") -AnnotationAssertion( "-2") -AnnotationAssertion( "C5H7O6PR2") -AnnotationAssertion( "194.07920") -AnnotationAssertion( "193.99802") -AnnotationAssertion( "O[C@H]1[C@@H]([*])[C@H]([*])O[C@@H]1COP([O-])([O-])=O") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "UniProt") "a nucleoside 5'-phosphate") -AnnotationAssertion(Annotation( "ChEBI") "nucleoside 5'-phosphate dianions") -AnnotationAssertion( "CHEBI:57867") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "nucleoside 5'-phosphate dianion") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (tryptaminium) - -AnnotationAssertion( "An ammonium ion that is the conjugate acid of tryptamine arising from protonation of the primary amino group; major species at pH 7.3.") -AnnotationAssertion( "+1") -AnnotationAssertion( "C10H13N2") -AnnotationAssertion( "InChI=1S/C10H12N2/c11-6-5-8-7-12-10-4-2-1-3-9(8)10/h1-4,7,12H,5-6,11H2/p+1") -AnnotationAssertion( "APJYDQYYACXCRM-UHFFFAOYSA-O") -AnnotationAssertion( "161.22310") -AnnotationAssertion( "161.10732") -AnnotationAssertion( "[NH3+]CCc1c[nH]c2ccccc12") -AnnotationAssertion(Annotation( "Gmelin") "Gmelin:533978") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "2-(1H-indol-3-yl)ethanaminium") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "UniProt") "tryptamine") -AnnotationAssertion(Annotation( "ChEBI") "tryptaminium cation") -AnnotationAssertion(Annotation( "ChEBI") "tryptaminium(1+)") -AnnotationAssertion( "CHEBI:57887") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "tryptaminium") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (nucleoside 5'-diphosphate(3-)) - -AnnotationAssertion( "Trianion of nucleoside diphosphate arising from deprotonation of all three free OH groups of the diphosphate; major species at pH 7.3.") -AnnotationAssertion( "-3") -AnnotationAssertion( "C5H8O10P2R") -AnnotationAssertion( "290.059") -AnnotationAssertion( "289.95927") -AnnotationAssertion( "[C@H]1([C@H]([C@@H](O)[C@@H](O1)*)O)COP(OP([O-])(=O)[O-])(=O)[O-]") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "NDP trianion") -AnnotationAssertion(Annotation( "ChEBI") "NDP(3-)") -AnnotationAssertion(Annotation( "UniProt") "a ribonucleoside 5'-diphosphate") -AnnotationAssertion(Annotation( "ChEBI") "nucleoside diphosphate trianion") -AnnotationAssertion(Annotation( "ChEBI") "ribonucleoside diphosphate trianion") -AnnotationAssertion(Annotation( "ChEBI") "ribonucleoside diphosphate(3-)") -AnnotationAssertion( "CHEBI:57930") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "nucleoside 5'-diphosphate(3-)") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (bilirubin(2-)) AnnotationAssertion( "A dicarboxylic acid dianion obtained by deprotonation of the two carboxy groups of bilirubin; major species at pH 7.3.") @@ -28785,49 +14251,6 @@ SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (nucleoside 5'-triphoshate(3-)) - -AnnotationAssertion( "Trianion of nucleoside triphosphate arising from deprotonation of three of the four free triphosphate OH groups.") -AnnotationAssertion( "-3") -AnnotationAssertion( "C5H9O13P3R") -AnnotationAssertion( "370.039") -AnnotationAssertion( "369.92560") -AnnotationAssertion( "[C@H]1([C@H]([C@@H](O)[C@@H](O1)*)O)COP(OP(OP(=O)([O-])O)(=O)[O-])(=O)[O-]") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "NTP trianion") -AnnotationAssertion(Annotation( "ChEBI") "NTP(3-)") -AnnotationAssertion(Annotation( "ChEBI") "nucleoside triphosphate trianion") -AnnotationAssertion(Annotation( "ChEBI") "ribonucleoside triphosphate trianion") -AnnotationAssertion(Annotation( "ChEBI") "ribonucleoside triphosphate(3-)") -AnnotationAssertion( "CHEBI:58104") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "nucleoside 5'-triphoshate(3-)") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (histaminium) - -AnnotationAssertion( "An ammonium ion that is the conjugate acid of histamine protonated on the side-chain nitrogen.") -AnnotationAssertion( "+1") -AnnotationAssertion( "C5H10N3") -AnnotationAssertion( "InChI=1S/C5H9N3/c6-2-1-5-3-7-4-8-5/h3-4H,1-2,6H2,(H,7,8)/p+1") -AnnotationAssertion( "NTYJJOPFIAHURM-UHFFFAOYSA-O") -AnnotationAssertion( "112.15300") -AnnotationAssertion( "112.08692") -AnnotationAssertion( "[NH3+]CCc1c[nH]cn1") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "2-(1H-imidazol-4-yl)ethanaminium") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "UniProt") "histamine") -AnnotationAssertion(Annotation( "ChEBI") "histaminium cation") -AnnotationAssertion( "CHEBI:58432") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "histaminium") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (organophosphate oxoanion) AnnotationAssertion( "An organic phosphoric acid derivative in which one or more oxygen atoms of the phosphate group(s) has been deprotonated.") @@ -28839,44 +14262,6 @@ AnnotationAssertion(rdfs:label "org SubClassOf( ) SubClassOf( ) -# Class: (short-chain fatty acid anion) - -AnnotationAssertion( "Any fatty acid anion obtained by removal of a proton from the carboxy group of a short-chain fatty acid (chain length of less than C6).") -AnnotationAssertion( "-1") -AnnotationAssertion( "CO2R") -AnnotationAssertion( "44.010") -AnnotationAssertion( "43.98983") -AnnotationAssertion( "[O-]C([*])=O") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "UniProt") "a short-chain fatty acid") -AnnotationAssertion(Annotation( "ChEBI") "short-chain fatty acid anions") -AnnotationAssertion( "CHEBI:58951") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "short-chain fatty acid anion") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (saturated fatty acid anion) - -AnnotationAssertion( "Any fatty acid anion in which there is no C-C unsaturation.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "saturated fatty acid anions") -AnnotationAssertion( "CHEBI:58953") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "saturated fatty acid anion") -SubClassOf( ) - -# Class: (straight-chain saturated fatty acid anion) - -AnnotationAssertion( "Any saturated fatty acid anion lacking a carbon side-chain.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "straight-chain saturated fatty acid anions") -AnnotationAssertion( "CHEBI:58954") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "straight-chain saturated fatty acid anion") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (organosulfate oxoanion) AnnotationAssertion( "An organic anion of general formula RS(=O)2O(-) where R is an organyl group.") @@ -28895,30 +14280,6 @@ SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (straight-chain fatty acid) - -AnnotationAssertion( "Any fatty acid whose skeletal carbon atoms form an unbranched open chain.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "straight-chain fatty acids") -AnnotationAssertion( "CHEBI:59202") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "straight-chain fatty acid") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (straight-chain fatty acid anion) - -AnnotationAssertion( "A fatty acid anion formed by deprotonation of the carboxylic acid functional group of a straight-chain fatty acid.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "straight-chain FA anion") -AnnotationAssertion(Annotation( "ChEBI") "straight-chain FA anions") -AnnotationAssertion(Annotation( "ChEBI") "straight-chain fatty acid anions") -AnnotationAssertion( "CHEBI:59203") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "straight-chain fatty acid anion") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (linear tetrapyrrole anion) AnnotationAssertion( "An organic anion arising from deprotonation of a acyclic tetrapyrrole compound.") @@ -28940,18 +14301,6 @@ AnnotationAssertion( "phosphoric acids") SubClassOf( ) -# Class: (ribonucleoside triphosphate oxoanion) - -AnnotationAssertion( "An organophosphate anion resulting from deprotonation of at least one of the acidic hydroxy groups from the triphosphate moiety of a nucleoside triphosphate.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "ribonucleoside triphosphate anion") -AnnotationAssertion(Annotation( "ChEBI") "ribonucleoside triphosphate anions") -AnnotationAssertion(Annotation( "ChEBI") "ribonucleoside triphosphate oxoanions") -AnnotationAssertion( "CHEBI:59724") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "ribonucleoside triphosphate oxoanion") -SubClassOf( ) - # Class: (nucleophilic reagent) AnnotationAssertion( "A reagent that forms a bond to its reaction partner (the electrophile) by donating both bonding electrons.") @@ -28965,111 +14314,6 @@ AnnotationAssertion(rdfs:label "nuc SubClassOf( ) SubClassOf( ) -# Class: (L-alpha-amino acid anion) - -AnnotationAssertion( "Conjugate base of an L-alpha-amino acid arising from deprotonation of the C-1 carboxy group.") -AnnotationAssertion( "-1") -AnnotationAssertion( "C2H3NO2R") -AnnotationAssertion( "73.051") -AnnotationAssertion( "73.01638") -AnnotationAssertion( "[C@H](C(=O)[O-])(N)*") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "L-alpha-amino carboxylate") -AnnotationAssertion( "CHEBI:59814") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "L-alpha-amino acid anion") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (progestin) - -AnnotationAssertion( "A synthetic progestogen.") -AnnotationAssertion( "Wikipedia:Progestin") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "progestins") -AnnotationAssertion( "CHEBI:59826") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "progestin") -SubClassOf( ) - -# Class: (L-alpha-amino acid zwitterion) - -AnnotationAssertion( "Zwitterionic form of an L-alpha-amino acid having an anionic carboxy group and a protonated amino group.") -AnnotationAssertion( "0") -AnnotationAssertion( "C2H4NO2R") -AnnotationAssertion( "74.059") -AnnotationAssertion( "74.02420") -AnnotationAssertion( "[NH3+][C@@H]([*])C([O-])=O") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "L-alpha-amino acid zwitterions") -AnnotationAssertion(Annotation( "UniProt") "an L-alpha-amino acid") -AnnotationAssertion( "CHEBI:59869") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "L-alpha-amino acid zwitterion") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (D-alpha-amino acid zwitterion) - -AnnotationAssertion( "Zwitterionic form of a D-alpha-amino acid having an anionic carboxy group and a protonated amino group.") -AnnotationAssertion( "0") -AnnotationAssertion( "C2H4NO2R") -AnnotationAssertion( "74.059") -AnnotationAssertion( "74.02420") -AnnotationAssertion( "[NH3+][C@H]([*])C([O-])=O") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "D-alpha-amino acid zwitterions") -AnnotationAssertion(Annotation( "UniProt") "a D-alpha-amino acid") -AnnotationAssertion( "CHEBI:59871") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "D-alpha-amino acid zwitterion") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (gamma-aminobutyric acid zwitterion) - -AnnotationAssertion( "Zwitterionic form of gamma-aminobutyric acid having an anionic carboxy group and a protonated amino group.") -AnnotationAssertion( "0") -AnnotationAssertion( "C4H9NO2") -AnnotationAssertion( "InChI=1S/C4H9NO2/c5-3-1-2-4(6)7/h1-3,5H2,(H,6,7)") -AnnotationAssertion( "BTCSSZJGUNDROE-UHFFFAOYSA-N") -AnnotationAssertion( "103.11980") -AnnotationAssertion( "103.06333") -AnnotationAssertion( "[NH3+]CCCC([O-])=O") -AnnotationAssertion(Annotation( "Gmelin") "Gmelin:1041559") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "4-azaniumylbutanoate") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "UniProt") "4-aminobutanoate") -AnnotationAssertion(Annotation( "ChEBI") "4-ammoniobutanoate") -AnnotationAssertion( "CHEBI:59888") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "gamma-aminobutyric acid zwitterion") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (dopaminium(1+)) - -AnnotationAssertion( "An ammonium ion that is the conjugate acid of dopamine; major species at pH 7.3.") -AnnotationAssertion( "+1") -AnnotationAssertion( "C8H12NO2") -AnnotationAssertion( "InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2/p+1") -AnnotationAssertion( "VYFYYTLLBUKUHU-UHFFFAOYSA-O") -AnnotationAssertion( "154.18640") -AnnotationAssertion( "154.08626") -AnnotationAssertion( "[NH3+]CCc1ccc(O)c(O)c1") -AnnotationAssertion(Annotation( "Gmelin") "Gmelin:328863") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "2-(3,4-dihydroxyphenyl)ethanaminium") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "2-(3,4-dihydroxyphenyl)ethan-1-aminium") -AnnotationAssertion(Annotation( "UniProt") "dopamine") -AnnotationAssertion(Annotation( "ChEBI") "dopaminium cation") -AnnotationAssertion( "CHEBI:59905") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "dopaminium(1+)") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (chemical substance) AnnotationAssertion( "A chemical substance is a portion of matter of constant composition, composed of molecular entities of the same type or of different types.") @@ -29149,45 +14393,6 @@ AnnotationAssertion(rdfs:label "pep SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (adjuvant) - -AnnotationAssertion( "Any pharmacological or immunological agent that modifies the effect of other agents such as drugs or vaccines while having few if any direct effects when given by itself.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "adjuvants") -AnnotationAssertion( "CHEBI:60809") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "adjuvant") -SubClassOf( ) - -# Class: (D-alpha-amino acid anion) - -AnnotationAssertion( "Any alpha-amino acid anion in which the parent amino acid has D-configuration.") -AnnotationAssertion( "-1") -AnnotationAssertion( "C2H3NO2R") -AnnotationAssertion( "73.051") -AnnotationAssertion( "73.01638") -AnnotationAssertion( "[C@@H](C(=O)[O-])(N)*") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "D-alpha-amino acid anions") -AnnotationAssertion(Annotation( "ChEBI") "D-alpha-amino carboxylate") -AnnotationAssertion( "CHEBI:60895") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "D-alpha-amino acid anion") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (racemate) - -AnnotationAssertion( "A racemate is an equimolar mixture of a pair of enantiomers.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "melange racemique") -AnnotationAssertion(Annotation( "ChEBI") "racemates") -AnnotationAssertion(Annotation( "ChEBI") "racemic mixture") -AnnotationAssertion( "CHEBI:60911") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "racemate") -SubClassOf( ) - # Class: (keratan sulfate) AnnotationAssertion( "A sulfated glycosaminoglycan, a linear polymer that consists of the repeating disaccharide [3)-beta-Gal-(1->4)-beta-GlcNAc-(1->] and containing sulfo groups located at random positions.") @@ -29211,83 +14416,6 @@ AnnotationAssertion( "amino monosaccharide") SubClassOf( ) -# Class: (EC 3.5.1.98 (histone deacetylase) inhibitor) - -AnnotationAssertion( "An EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the function of histone deacetylase (EC 3.5.1.98).") -AnnotationAssertion( "Wikipedia:Histone_deacetylase_inhibitor") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "EC 3.5.1.98 (histone deacetylase) inhibitors") -AnnotationAssertion(Annotation( "ChEBI") "EC 3.5.1.98 inhibitor") -AnnotationAssertion(Annotation( "ChEBI") "EC 3.5.1.98 inhibitors") -AnnotationAssertion(Annotation( "ChEBI") "HDAC inhibitor") -AnnotationAssertion(Annotation( "ChEBI") "HDAC inhibitors") -AnnotationAssertion(Annotation( "ChEBI") "HDACi") -AnnotationAssertion(Annotation( "ChEBI") "HDACis") -AnnotationAssertion(Annotation( "ChEBI") "HDI") -AnnotationAssertion(Annotation( "ChEBI") "HDIs") -AnnotationAssertion(Annotation( "ChEBI") "histone amidohydrolase inhibitor") -AnnotationAssertion(Annotation( "ChEBI") "histone amidohydrolase inhibitors") -AnnotationAssertion(Annotation( "ChEBI") "histone deacetylase (EC 3.5.1.98) inhibitor") -AnnotationAssertion(Annotation( "ChEBI") "histone deacetylase (EC 3.5.1.98) inhibitors") -AnnotationAssertion(Annotation( "ChEBI") "histone deacetylase inhibitor") -AnnotationAssertion(Annotation( "ChEBI") "histone deacetylase inhibitors") -AnnotationAssertion( "CHEBI:61115") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "EC 3.5.1.98 (histone deacetylase) inhibitor") -SubClassOf( ) - -# Class: (nucleobase-containing molecular entity) - -AnnotationAssertion( "Any compound that has a nucleobase as a part.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "SUBMITTER") "nucleobase-containing compound") -AnnotationAssertion(Annotation( "ChEBI") "nucleobase-containing compounds") -AnnotationAssertion(Annotation( "ChEBI") "nucleobase-containing molecular entities") -AnnotationAssertion( "CHEBI:61120") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "nucleobase-containing molecular entity") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (adenyl nucleotide) - -AnnotationAssertion( "A nucleotide having adenine as the base.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "SUBMITTER") "adenine nucleotide") -AnnotationAssertion( "CHEBI:61293") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "adenyl nucleotide") -SubClassOf( ) - -# Class: (adenyl ribonucleotide) - -AnnotationAssertion( "A purine riboncleotide where adenine is the purine.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "SUBMITTER") "adenine ribonucleotide") -AnnotationAssertion( "CHEBI:61296") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "adenyl ribonucleotide") -SubClassOf( ) -SubClassOf( ) - -# Class: (C21-steroid) - -AnnotationAssertion( "A steroid that has a structure based on a 21-carbon (pregnane) skeleton. Note that individual examples may have ring substituents at other positions and/or contain double bonds, aromatic A-rings, expanded/contracted rings etc., so the formula and mass may vary from that given for the generic structure.") -AnnotationAssertion( "0") -AnnotationAssertion( "C21H36") -AnnotationAssertion( "InChI=1S/C21H36/c1-4-15-9-11-18-17-10-8-16-7-5-6-13-20(16,2)19(17)12-14-21(15,18)3/h15-19H,4-14H2,1-3H3") -AnnotationAssertion( "JWMFYGXQPXQEEM-UHFFFAOYSA-N") -AnnotationAssertion( "288.511") -AnnotationAssertion( "288.28170") -AnnotationAssertion( "C1CCCC2C1(C3C(CC2)C4C(CC3)(C(CC4)CC)C)C") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "UniProt") "a C21-steroid") -AnnotationAssertion( "CHEBI:61313") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "C21-steroid") -SubClassOf( ) - # Class: (polyanionic polymer) AnnotationAssertion( "A polymer, composed of polyanion macromolecules.") @@ -29300,57 +14428,6 @@ AnnotationAssertion(rdfs:label "pol SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (nucleoside 5'-triphoshate(4-)) - -AnnotationAssertion( "A ribonucleoside triphosphate oxoanion arising from global deprotonation of the triphosphate groups of any nucleoside triphosphate; major species at pH 7.3.") -AnnotationAssertion( "-4") -AnnotationAssertion( "C5H8O13P3R") -AnnotationAssertion( "369.031") -AnnotationAssertion( "368.91778") -AnnotationAssertion( "[C@H]1([C@H]([C@@H](O)[C@@H](O1)*)O)COP(OP(OP(=O)([O-])[O-])(=O)[O-])(=O)[O-]") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "NTP tetraanion") -AnnotationAssertion(Annotation( "SUBMITTER") "NTP(4-)") -AnnotationAssertion(Annotation( "UniProt") "a ribonucleoside 5'-triphosphate") -AnnotationAssertion(Annotation( "ChEBI") "nucleoside 5'-triphosphate tetraanion") -AnnotationAssertion(Annotation( "ChEBI") "nucleoside triphosphate(4-)") -AnnotationAssertion( "CHEBI:61557") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "nucleoside 5'-triphoshate(4-)") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (polar amino acid zwitterion) - -AnnotationAssertion( "Zwitterionic form of a polar amino acid having an anionic carboxy group and a protonated amino group.") -AnnotationAssertion( "0") -AnnotationAssertion( "C2H4NO2R") -AnnotationAssertion( "74.059") -AnnotationAssertion( "74.02420") -AnnotationAssertion( "C(C([O-])=O)(*)[NH3+]") -AnnotationAssertion(Annotation( "SUBMITTER") "MetaCyc:Polar-amino-acids") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "UniProt") "a polar amino acid") -AnnotationAssertion( "CHEBI:62031") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "polar amino acid zwitterion") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (signalling molecule) - -AnnotationAssertion( "A molecular messenger in which the molecule is specifically involved in transmitting information between cells. Such molecules are released from the cell sending the signal, cross over the gap between cells by diffusion, and interact with specific receptors in another cell, triggering a response in that cell by activating a series of enzyme controlled reactions which lead to changes inside the cell.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "signal molecule") -AnnotationAssertion(Annotation( "ChEBI") "signal molecules") -AnnotationAssertion(Annotation( "ChEBI") "signaling molecule") -AnnotationAssertion(Annotation( "ChEBI") "signaling molecules") -AnnotationAssertion(Annotation( "ChEBI") "signalling molecules") -AnnotationAssertion( "CHEBI:62488") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "signalling molecule") -SubClassOf( ) - # Class: (anionic phospholipid) AnnotationAssertion( "Any organophosphate oxoanion that is a negatively charged phospholipid, e.g. phosphatidylserine(1-), phosphatidate(2-), phosphatidylglycerol(1-).") @@ -29375,34 +14452,6 @@ AnnotationAssertion(rdfs:label "gly SubClassOf( ) SubClassOf( ) -# Class: (glycosyl compound) - -AnnotationAssertion( "A carbohydrate derivative arising formally from the elimination of water from a glycosidic hydroxy group and an H atom bound to an oxygen, carbon, nitrogen or sulfur atom of a separate entity.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "glycosyl compounds") -AnnotationAssertion( "CHEBI:63161") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "glycosyl compound") -SubClassOf( ) - -# Class: (oxidising agent) - -AnnotationAssertion( "A substance that removes electrons from another reactant in a redox reaction.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "oxidant") -AnnotationAssertion(Annotation( "ChEBI") "oxidants") -AnnotationAssertion(Annotation( "ChEBI") "oxidiser") -AnnotationAssertion(Annotation( "ChEBI") "oxidisers") -AnnotationAssertion(Annotation( "ChEBI") "oxidising agents") -AnnotationAssertion(Annotation( "ChEBI") "oxidizer") -AnnotationAssertion(Annotation( "ChEBI") "oxidizers") -AnnotationAssertion(Annotation( "ChEBI") "oxidizing agent") -AnnotationAssertion(Annotation( "ChEBI") "oxidizing agents") -AnnotationAssertion( "CHEBI:63248") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "oxidising agent") -SubClassOf( ) - # Class: (carbohydrate derivative) AnnotationAssertion( "Any organooxygen compound derived from a carbohydrate by replacement of one or more hydroxy group(s) by an amino group, a thiol group or similar heteroatomic groups. The term also includes derivatives of these compounds.") @@ -29418,28 +14467,6 @@ AnnotationAssertion(rdfs:label "car SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (monosaccharide derivative) - -AnnotationAssertion( "A carbohydrate derivative that is formally obtained from a monosaccharide.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "monosaccharide derivatives") -AnnotationAssertion( "CHEBI:63367") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "monosaccharide derivative") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (pentose derivative) - -AnnotationAssertion( "A monosaccharide derivative that is formally obtained from a pentose.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "pentose derivatives") -AnnotationAssertion( "CHEBI:63409") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "pentose derivative") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (carbohydrate acid derivative) AnnotationAssertion( "A carbohydrate derivative that is formally obtained from a carbohydrate acid.") @@ -29452,27 +14479,6 @@ SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (monoamine) - -AnnotationAssertion( "An aralylamino compound which contains one amino group connected to an aromatic ring by a two-carbon chain. Monoamines are derived from aromatic amino acids like phenylalanine, tyrosine, tryptophan, and the thyroid hormones by the action of aromatic amino acid decarboxylase enzymes.") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:21822758") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:21993877") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:22005599") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:22082101") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:22153577") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:22213370") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:22218931") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:22342987") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:22371656") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "monoamines") -AnnotationAssertion(Annotation( "ChEBI") "naturally occurring monoamine") -AnnotationAssertion(Annotation( "ChEBI") "naturally occurring monoamines") -AnnotationAssertion( "CHEBI:63534") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "monoamine") -SubClassOf( ) - # Class: (carbohydrate acid derivative anion) AnnotationAssertion( "A carboxylic acid anion resulting from the deprotonation of the carboxy group of a carbohydrate acid derivative.") @@ -29499,31 +14505,6 @@ AnnotationAssertion(rdfs:label "foo SubClassOf( ) SubClassOf( ) -# Class: (food acidity regulator) - -AnnotationAssertion( "A food additive that is used to change or otherwise control the acidity or alkalinity of foods. They may be acids, bases, neutralising agents or buffering agents.") -AnnotationAssertion( "Wikipedia:Acidity_regulator") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "acidity regulator") -AnnotationAssertion(Annotation( "ChEBI") "acidity regulators") -AnnotationAssertion(Annotation( "ChEBI") "food acidity regulators") -AnnotationAssertion(Annotation( "ChEBI") "pH control agent") -AnnotationAssertion(Annotation( "ChEBI") "pH control agents") -AnnotationAssertion( "CHEBI:64049") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "food acidity regulator") -SubClassOf( ) - -# Class: (aralkylamino compound) - -AnnotationAssertion( "An organic amino compound in which an aminoalkyl group is linked to an arene.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "aralkylamino compounds") -AnnotationAssertion( "CHEBI:64365") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "aralkylamino compound") -SubClassOf( ) - # Class: (sphingomyelin) AnnotationAssertion( "Any of a class of phospholipids in which the amino group of a sphingoid base is in amide linkage with one of several fatty acids, while the terminal hydroxy group of the sphingoid base is esterified to phosphorylcholine.") @@ -29545,59 +14526,6 @@ SubClassOf( ) SubClassOf( ) -# Class: (C21-steroid hormone) - -AnnotationAssertion( "A steroid compound with a structure based on a 21-carbon (pregnane) skeleton that acts as a hormone.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "C21-steroid hormones") -AnnotationAssertion( "CHEBI:64600") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "C21-steroid hormone") -SubClassOf( ) -SubClassOf( ) - -# Class: (somatostatin) - -AnnotationAssertion( "A fourteen-membered heterodetic cyclic peptide comprising the sequence Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys cyclised by a disulfide bridge between the two Cys residues at positions 3 and 14.") -AnnotationAssertion( "0") -AnnotationAssertion( "C76H104N18O19S2") -AnnotationAssertion( "InChI=1S/C76H104N18O19S2/c1-41(79)64(100)82-37-61(99)83-58-39-114-115-40-59(76(112)113)92-72(108)57(38-95)91-75(111)63(43(3)97)94-71(107)54(33-46-23-11-6-12-24-46)90-74(110)62(42(2)96)93-66(102)51(28-16-18-30-78)84-69(105)55(34-47-36-81-49-26-14-13-25-48(47)49)88-68(104)53(32-45-21-9-5-10-22-45)86-67(103)52(31-44-19-7-4-8-20-44)87-70(106)56(35-60(80)98)89-65(101)50(85-73(58)109)27-15-17-29-77/h4-14,19-26,36,41-43,50-59,62-63,81,95-97H,15-18,27-35,37-40,77-79H2,1-3H3,(H2,80,98)(H,82,100)(H,83,99)(H,84,105)(H,85,109)(H,86,103)(H,87,106)(H,88,104)(H,89,101)(H,90,110)(H,91,111)(H,92,108)(H,93,102)(H,94,107)(H,112,113)/t41-,42+,43+,50-,51-,52-,53-,54-,55-,56-,57-,58-,59-,62-,63-/m0/s1") -AnnotationAssertion( "NHXLMOGPVYXJNR-ATOGVRKGSA-N") -AnnotationAssertion( "1637.87800") -AnnotationAssertion( "1636.71666") -AnnotationAssertion( "C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC1=O)[C@@H](C)O)C(O)=O)NC(=O)CNC(=O)[C@H](C)N") -AnnotationAssertion(Annotation( "ChemIDplus") "CAS:38916-34-6") -AnnotationAssertion(Annotation( "KEGG DRUG") "CAS:38916-34-6") -AnnotationAssertion(Annotation( "DrugCentral") "Drug_Central:2997") -AnnotationAssertion( "HMDB:HMDB0013072") -AnnotationAssertion( "KEGG:C16022") -AnnotationAssertion( "KEGG:D07431") -AnnotationAssertion( "LINCS:LSM-5326") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:21922516") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:22129035") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:22147011") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:22251942") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:22483686") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:22509294") -AnnotationAssertion(Annotation( "Reaxys") "Reaxys:10148626") -AnnotationAssertion( "Wikipedia:Somatostatin") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "L-alanyl-N-[(4R,7S,10S,13S,16S,19S,22S,25S,28S,31S,34S,37R)-19,34-bis(4-aminobutyl)-31-(2-amino-2-oxoethyl)-13,25,28-tribenzyl-4-carboxy-10,16-bis[(1R)-1-hydroxyethyl]-7-(hydroxymethyl)-22-(1H-indol-3-ylmethyl)-6,9,12,15,18,21,24,27,30,33,36-undecaoxo-1,2-dithia-5,8,11,14,17,20,23,26,29,32,35-undecaazacyclooctatriacontan-37-yl]glycinamide") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "Ala-Gly-cyclo-[Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys]") -AnnotationAssertion(Annotation( "ChemIDplus") "L-alanylglycyl-L-cysteinyl-L-lysyl-L-asparaginyl-L-phenylalanyl-L-phenylalanyl-L-tryptophyl-L-lysyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-cysteine cyclic (3-14) disulfide") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Somatostatin-1") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Somatostatin-14") -AnnotationAssertion(Annotation( "ChemIDplus") "Synthetic growth hormone release-inhibiting hormone") -AnnotationAssertion(Annotation( "KEGG_DRUG") Annotation( ) "somatostatin") -AnnotationAssertion(Annotation( "ChemIDplus") Annotation( ) "somatostatina") -AnnotationAssertion(Annotation( "ChemIDplus") Annotation( ) "somatostatine") -AnnotationAssertion(Annotation( "ChemIDplus") Annotation( ) "somatostatinum") -AnnotationAssertion( "CHEBI:64628") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "somatostatin") -SubClassOf( ) -SubClassOf( ) - # Class: (divalent inorganic cation) AnnotationAssertion( "An inorganic cation with a valency of two.") @@ -29675,29 +14603,6 @@ SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (food preservative) - -AnnotationAssertion( "Substances which are added to food in order to prevent decomposition caused by microbial growth or by undesirable chemical changes.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "food preservatives") -AnnotationAssertion( "CHEBI:65255") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "food preservative") -SubClassOf( ) - -# Class: (antimicrobial food preservative) - -AnnotationAssertion( "A food preservative which prevents decomposition of food by preventing the growth of fungi or bacteria. In European countries, E-numbers for permitted food preservatives are from E200 to E299, divided into sorbates (E200-209), benzoates (E210-219), sulfites (E220-229), phenols and formates (E230-239), nitrates (E240-259), acetates (E260-269), lactates (E270-279), propionates (E280-289) and others (E290-299).") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "antimicrobial food preservatives") -AnnotationAssertion(Annotation( "ChEBI") "antimicrobial preservative") -AnnotationAssertion(Annotation( "ChEBI") "antimicrobial preservatives") -AnnotationAssertion( "CHEBI:65256") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "antimicrobial food preservative") -SubClassOf( ) -SubClassOf( ) - # Class: (antacid) AnnotationAssertion( "Any substance which is used to neutralise stomach acidity.") @@ -29710,36 +14615,6 @@ AnnotationAssertion(rdfs:label "ant SubClassOf( ) SubClassOf( ) -# Class: (primary ammonium ion) - -AnnotationAssertion( "An ammonium ion derivative resulting from the protonation of the nitrogen atom of a primary amino compound. Major species at pH 7.3.") -AnnotationAssertion( "+1") -AnnotationAssertion( "H3NR") -AnnotationAssertion( "17.031") -AnnotationAssertion( "17.02655") -AnnotationAssertion( "[NH3+][*]") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "UniProt") "a primary amine") -AnnotationAssertion(Annotation( "ChEBI") "substituted ammonium") -AnnotationAssertion( "CHEBI:65296") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "primary ammonium ion") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (anti-inflammatory agent) - -AnnotationAssertion( "Any compound that has anti-inflammatory effects.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "anti-inflammatory agents") -AnnotationAssertion(Annotation( "ChEBI") "antiinflammatory agent") -AnnotationAssertion(Annotation( "ChEBI") "antiinflammatory agents") -AnnotationAssertion( "CHEBI:67079") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "anti-inflammatory agent") -SubClassOf( ) - # Class: (provitamin A) AnnotationAssertion( "A provitamin that can be converted into vitamin A by enzymes from animal tissues.") @@ -29750,92 +14625,6 @@ AnnotationAssertion( "provitamin A") SubClassOf( ) -# Class: (azole) - -AnnotationAssertion( "Any monocyclic heteroarene consisting of a five-membered ring containing nitrogen. Azoles can also contain one or more other non-carbon atoms, such as nitrogen, sulfur or oxygen.") -AnnotationAssertion( "Wikipedia:Azole") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "azoles") -AnnotationAssertion( "CHEBI:68452") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "azole") -SubClassOf( ) -SubClassOf( ) - -# Class: (progesterone receptor agonist) - -AnnotationAssertion( "A hormone agonist that binds to and activates progesterone receptors.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "PR agonist") -AnnotationAssertion(Annotation( "ChEBI") "PR agonists") -AnnotationAssertion(Annotation( "ChEBI") "progesterone receptor agonists") -AnnotationAssertion( "CHEBI:70709") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "progesterone receptor agonist") -SubClassOf( ) - -# Class: ((R)-adrenaline(1+)) - -AnnotationAssertion( "An organic cation that is the conjugate acid of (R)-adrenaline, obtained by protonation of the amino group; major species at pH 7.3.") -AnnotationAssertion( "+1") -AnnotationAssertion( "C9H14NO3") -AnnotationAssertion( "InChI=1S/C9H13NO3/c1-10-5-9(13)6-2-3-7(11)8(12)4-6/h2-4,9-13H,5H2,1H3/p+1/t9-/m0/s1") -AnnotationAssertion( "UCTWMZQNUQWSLP-VIFPVBQESA-O") -AnnotationAssertion( "184.21240") -AnnotationAssertion( "184.09682") -AnnotationAssertion( "C[NH2+]C[C@H](O)c1ccc(O)c(O)c1") -AnnotationAssertion( "MetaCyc:L-EPINEPHRINE") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "(2R)-2-(3,4-dihydroxyphenyl)-2-hydroxy-N-methylethanaminium") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "UniProt") "(R)-adrenaline") -AnnotationAssertion(Annotation( "ChEBI") "(R)-adrenaline cation") -AnnotationAssertion(Annotation( "ChEBI") "L-epinephrine cation") -AnnotationAssertion(Annotation( "ChEBI") "L-epinephrine(1+)") -AnnotationAssertion( "CHEBI:71406") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "(R)-adrenaline(1+)") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (gamma-amino acid anion) - -AnnotationAssertion( "An amino-acid anion in which the amino group is situated gamma- to the carboxylate group.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "gamma-amino acid anions") -AnnotationAssertion( "CHEBI:71666") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "gamma-amino acid anion") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: ((R)-noradrenaline(1+)) - -AnnotationAssertion( "An organic cation that is the conjugate acid of (R)-noradrenaline, obtained by protonation of the priamry amino group; major species at pH 7.3.") -AnnotationAssertion( "+1") -AnnotationAssertion( "C8H12NO3") -AnnotationAssertion( "InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2/p+1/t8-/m0/s1") -AnnotationAssertion( "SFLSHLFXELFNJZ-QMMMGPOBSA-O") -AnnotationAssertion( "170.187") -AnnotationAssertion( "170.08117") -AnnotationAssertion( "C=1(C=CC(=CC1O)[C@H](C[NH3+])O)O") -AnnotationAssertion( "PDBeChem:E5E") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "(2R)-2-(3,4-dihydroxyphenyl)-2-hydroxyethanaminium") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "UniProt") "(R)-noradrenaline") -AnnotationAssertion(Annotation( "ChEBI") "(R)-noradrenaline cation") -AnnotationAssertion(Annotation( "ChEBI") "(R)-noradrenalinium cation") -AnnotationAssertion(Annotation( "ChEBI") "(R)-noradrenalinium(1+)") -AnnotationAssertion( "CHEBI:72587") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "(R)-noradrenaline(1+)") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (organic molecule) AnnotationAssertion( "Any molecule that consists of at least one carbon atom as part of the electrically neutral entity.") @@ -29892,80 +14681,6 @@ AnnotationAssertion( "vulnerary") SubClassOf( ) -# Class: (indole skeleton) - -AnnotationAssertion( "A mancude heterobicyclic organic group consisting of a benzene ring fused to a pyrrole ring.") -AnnotationAssertion( "0") -AnnotationAssertion( "C8N") -AnnotationAssertion( "110.09230") -AnnotationAssertion( "110.00307") -AnnotationAssertion( "C1(=C(C(=C2C(=C1*)N(C(=C2*)*)*)*)*)*") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion( "CHEBI:73398") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "indole skeleton") -SubClassOf( ) - -# Class: (organic heterobicyclic ring) - -AnnotationAssertion( "A bicyclic organic group that contains both carbon and hetero atoms.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "organic heterobicyclic rings") -AnnotationAssertion( "CHEBI:73541") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "organic heterobicyclic ring") -SubClassOf( ) - -# Class: (astringent) - -AnnotationAssertion( "A compound that causes the contraction of body tissues, typically used to reduce bleeding from minor abrasions.") -AnnotationAssertion( "Wikipedia:Astringent") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "adstringent") -AnnotationAssertion(Annotation( "ChEBI") "adstringents") -AnnotationAssertion(Annotation( "ChEBI") "astringents") -AnnotationAssertion( "CHEBI:74783") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "astringent") -SubClassOf( ) - -# Class: (EC 6.3.* (C-N bond-forming ligase) inhibitor) - -AnnotationAssertion( "A ligase inhibitor that interferes with the action of a C-N bond-forming ligase (EC 6.3.*.*).") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "C--N bond-forming ligase inhibitor") -AnnotationAssertion(Annotation( "ChEBI") "C--N bond-forming ligase inhibitors") -AnnotationAssertion(Annotation( "ChEBI") "C-N bond-forming ligase (EC 6.3.*) inhibitor") -AnnotationAssertion(Annotation( "ChEBI") "C-N bond-forming ligase (EC 6.3.*) inhibitors") -AnnotationAssertion(Annotation( "ChEBI") "C-N bond-forming ligase inhibitor") -AnnotationAssertion(Annotation( "ChEBI") "C-N bond-forming ligase inhibitors") -AnnotationAssertion(Annotation( "ChEBI") "EC 6.3.* (C-N bond-forming ligase) inhibitorS") -AnnotationAssertion(Annotation( "ChEBI") "EC 6.3.* inhibitor") -AnnotationAssertion(Annotation( "ChEBI") "EC 6.3.* inhibitors") -AnnotationAssertion(Annotation( "ChEBI") "EC 6.3.*.* inhibitor") -AnnotationAssertion(Annotation( "ChEBI") "EC 6.3.*.* inhibitors") -AnnotationAssertion( "CHEBI:75600") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "EC 6.3.* (C-N bond-forming ligase) inhibitor") -SubClassOf( ) - -# Class: (EC 6.* (ligase) inhibitor) - -AnnotationAssertion( "Any enzyme inhibitor that interferes with the action of a ligase (EC 6.*.*.*). Ligases are enzymes that catalyse the joining of two molecules with concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.") -AnnotationAssertion( "Wikipedia:Ligase") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "EC 6.* (ligase) inhibitors") -AnnotationAssertion(Annotation( "ChEBI") "EC 6.* inhibitor") -AnnotationAssertion(Annotation( "ChEBI") "EC 6.* inhibitors") -AnnotationAssertion(Annotation( "ChEBI") "EC 6.*.*.* inhibitor") -AnnotationAssertion(Annotation( "ChEBI") "EC 6.*.*.* inhibitors") -AnnotationAssertion(Annotation( "ChEBI") "ligase inhibitor") -AnnotationAssertion(Annotation( "ChEBI") "ligase inhibitors") -AnnotationAssertion( "CHEBI:75603") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "EC 6.* (ligase) inhibitor") -SubClassOf( ) - # Class: (eukaryotic metabolite) AnnotationAssertion( "Any metabolite produced during a metabolic reaction in eukaryotes, the taxon that include members of the fungi, plantae and animalia kingdoms.") @@ -30043,16 +14758,6 @@ AnnotationAssertion( "prokaryotic metabolite") SubClassOf( ) -# Class: (xenobiotic metabolite) - -AnnotationAssertion( "Any metabolite produced by metabolism of a xenobiotic compound.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "xenobiotic metabolites") -AnnotationAssertion( "CHEBI:76206") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "xenobiotic metabolite") -SubClassOf( ) - # Class: (greenhouse gas) AnnotationAssertion( "A gas in an atmosphere that absorbs and emits radiation within the thermal infrared range, so contributing to the 'greenhouse effect'.") @@ -30125,20 +14830,6 @@ AnnotationAssertion( "EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor") SubClassOf( ) -# Class: (EC 6.3.1.* (acid-ammonia/amine ligase) inhibitor) - -AnnotationAssertion( "An EC 6.3.* (C-N bond-forming ligase) inhibitor that interferes with the action of any acid-ammonia (or amine) ligase (EC 6.3.1.*).") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "EC 6.3.1.* (acid-ammonia/amine ligase) inhibitors") -AnnotationAssertion(Annotation( "ChEBI") "EC 6.3.1.* inhibitor") -AnnotationAssertion(Annotation( "ChEBI") "EC 6.3.1.* inhibitors") -AnnotationAssertion(Annotation( "ChEBI") "acid-ammonia (or amine) ligase inhibitor") -AnnotationAssertion(Annotation( "ChEBI") "acid-ammonia (or amine) ligase inhibitors") -AnnotationAssertion( "CHEBI:76823") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "EC 6.3.1.* (acid-ammonia/amine ligase) inhibitor") -SubClassOf( ) - # Class: (plant metabolite) AnnotationAssertion( "Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms.") @@ -30164,17 +14855,6 @@ AnnotationAssertion( "fungal metabolite") SubClassOf( ) -# Class: (human xenobiotic metabolite) - -AnnotationAssertion( "Any human metabolite produced by metabolism of a xenobiotic compound in humans.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "human xenobiotic metabolites") -AnnotationAssertion( "CHEBI:76967") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "human xenobiotic metabolite") -SubClassOf( ) -SubClassOf( ) - # Class: (bacterial metabolite) AnnotationAssertion( "Any prokaryotic metabolite produced during a metabolic reaction in bacteria.") @@ -30290,23 +14970,6 @@ AnnotationAssertion(rdfs:label "foo SubClassOf( ) SubClassOf( ) -# Class: (fatty acid anion 4:0) - -AnnotationAssertion( "Any saturated fatty acid anion containing 4 carbons. Formed by deprotonation of the carboxylic acid moiety. Major species at pH 7.3.") -AnnotationAssertion( "-1") -AnnotationAssertion( "C4H7O2") -AnnotationAssertion( "87.09718") -AnnotationAssertion( "87.04460") -AnnotationAssertion( "[O-]C([*])=O") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "UniProt") "fatty acid 4:0") -AnnotationAssertion( "CHEBI:78115") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "fatty acid anion 4:0") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (food component) AnnotationAssertion( "A physiological role played by any substance that is distributed in foodstuffs. It includes materials derived from plants or animals, such as vitamins or minerals, as well as environmental contaminants.") @@ -30359,28 +15022,6 @@ AnnotationAssertion( "carbohydrates and carbohydrate derivatives") SubClassOf( ) -# Class: (fundamental metabolite) - -AnnotationAssertion( "Any metabolite produced by all living cells.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "essential metabolite") -AnnotationAssertion(Annotation( "ChEBI") "essential metabolites") -AnnotationAssertion(Annotation( "ChEBI") "fundamental metabolites") -AnnotationAssertion( "CHEBI:78675") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "fundamental metabolite") -SubClassOf( ) - -# Class: (olefinic compound) - -AnnotationAssertion( "Any organic molecular entity that contains at least one C=C bond.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "olefinic compounds") -AnnotationAssertion( "CHEBI:78840") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "olefinic compound") -SubClassOf( ) - # Class: (trivalent inorganic anion) AnnotationAssertion( "Any inorganic anion with a valency of three.") @@ -30411,16 +15052,6 @@ AnnotationAssertion( "monovalent inorganic anion") SubClassOf( ) -# Class: (elemental iron) - -AnnotationAssertion( "An elemental molecular entity in which all of the atoms have atomic number 26.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion( "CHEBI:82663") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "elemental iron") -SubClassOf( ) -SubClassOf( ) - # Class: (crustacean metabolite) AnnotationAssertion( "An animal metabolite produced by arthropods such as crabs, lobsters, crayfish, shrimps and krill.") @@ -30486,115 +15117,6 @@ SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (proteinogenic amino acid) - -AnnotationAssertion( "Any of the 23 alpha-amino acids that are precursors to proteins, and are incorporated into proteins during translation. The group includes the 20 amino acids encoded by the nuclear genes of eukaryotes together with selenocysteine, pyrrolysine, and N-formylmethionine. Apart from glycine, which is non-chiral, all have L configuration.") -AnnotationAssertion( "Wikipedia:Proteinogenic_amino_acid") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "canonical amino acid") -AnnotationAssertion(Annotation( "ChEBI") "canonical amino acids") -AnnotationAssertion(Annotation( "ChEBI") "proteinogenic amino acids") -AnnotationAssertion( "CHEBI:83813") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "proteinogenic amino acid") -SubClassOf( ) -SubClassOf( ) - -# Class: (non-proteinogenic amino acid) - -AnnotationAssertion( "Any amino-acid that is not naturally encoded in the genetic code of any organism.") -AnnotationAssertion( "Wikipedia:Non-proteinogenic_amino_acids") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "non-canonical amino acid") -AnnotationAssertion(Annotation( "ChEBI") "non-canonical amino acids") -AnnotationAssertion(Annotation( "ChEBI") "non-canonical amino-acid") -AnnotationAssertion(Annotation( "ChEBI") "non-canonical amino-acids") -AnnotationAssertion(Annotation( "ChEBI") "non-coded amino acid") -AnnotationAssertion(Annotation( "ChEBI") "non-coded amino acids") -AnnotationAssertion(Annotation( "ChEBI") "non-coded amino-acid") -AnnotationAssertion(Annotation( "ChEBI") "non-coded amino-acids") -AnnotationAssertion(Annotation( "ChEBI") "non-proteinogenic amino acids") -AnnotationAssertion(Annotation( "ChEBI") "non-proteinogenic amino-acid") -AnnotationAssertion(Annotation( "ChEBI") "non-proteinogenic amino-acids") -AnnotationAssertion( "CHEBI:83820") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "non-proteinogenic amino acid") -SubClassOf( ) - -# Class: (amino acid derivative) - -AnnotationAssertion( "Any derivative of an amino acid resulting from reaction at an amino group, carboxy group, side-chain functional group, or from the replacement of any hydrogen by a heteroatom. The definition normally excludes peptides containing amino acid residues.") -AnnotationAssertion( "CHEBI:25359") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "amino acid derivatives") -AnnotationAssertion(Annotation( "ChEBI") "modified amino acids") -AnnotationAssertion( "CHEBI:83821") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "amino acid derivative") -SubClassOf( ) - -# Class: (pregnane) - -AnnotationAssertion( "0") -AnnotationAssertion( "C21H36") -AnnotationAssertion( "InChI=1S/C21H36/c1-4-15-9-11-18-17-10-8-16-7-5-6-13-20(16,2)19(17)12-14-21(15,18)3/h15-19H,4-14H2,1-3H3/t15-,16?,17-,18-,19-,20-,21+/m0/s1") -AnnotationAssertion( "JWMFYGXQPXQEEM-WZBAXQLOSA-N") -AnnotationAssertion( "288.51054") -AnnotationAssertion( "288.28170") -AnnotationAssertion( "[H][C@]1(CC)CC[C@@]2([H])[C@]3([H])CCC4([H])CCCC[C@]4(C)[C@@]3([H])CC[C@]12C") -AnnotationAssertion(Annotation( "LIPID MAPS") "LIPID_MAPS_instance:LMST02030000") -AnnotationAssertion( "Wikipedia:Pregnane") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "pregnane") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion( "CHEBI:8386") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "pregnane") -SubClassOf( ) - -# Class: (non-proteinogenic alpha-amino acid) - -AnnotationAssertion( "Any alpha-amino acid which is not a member of the group of 23 proteinogenic amino acids.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "non-proteinogenic alpha-amino acids") -AnnotationAssertion(Annotation( "ChEBI") "non-proteinogenic alpha-amino-acid") -AnnotationAssertion(Annotation( "ChEBI") "non-proteinogenic alpha-amino-acids") -AnnotationAssertion( "CHEBI:83925") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "non-proteinogenic alpha-amino acid") -SubClassOf( ) -SubClassOf( ) - -# Class: (pentose phosphate) - -AnnotationAssertion( "Any phospho sugar that is the phosphate derivative of pentose.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "pentose phosphates") -AnnotationAssertion( "CHEBI:84055") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "pentose phosphate") -SubClassOf( ) -SubClassOf( ) - -# Class: (human urinary metabolite) - -AnnotationAssertion( "Any metabolite (endogenous or exogenous) found in human urine samples.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "human urinary metabolites") -AnnotationAssertion( "CHEBI:84087") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "human urinary metabolite") -SubClassOf( ) - -# Class: (hydroxyindoles) - -AnnotationAssertion( "Any member of the class of indoles carrying at least one hydroxy group.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion( "CHEBI:84729") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "hydroxyindoles") -SubClassOf( ) -SubClassOf( ) - # Class: (algal metabolite) AnnotationAssertion( "Any eukaryotic metabolite produced during a metabolic reaction in algae including unicellular organisms like chlorella and diatoms to multicellular organisms like giant kelps and brown algae.") @@ -30605,66 +15127,6 @@ AnnotationAssertion( "algal metabolite") SubClassOf( ) -# Class: (ADP(2-)) - -AnnotationAssertion( "An organophosphate oxoanion obtained by deprotonation of two of the three diphosphate OH groups of adenosine 5'-diphosphate.") -AnnotationAssertion( "-2") -AnnotationAssertion( "C10H13N5O10P2") -AnnotationAssertion( "InChI=1S/C10H15N5O10P2/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(24-10)1-23-27(21,22)25-26(18,19)20/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H2,11,12,13)(H2,18,19,20)/p-2/t4-,6-,7-,10-/m1/s1") -AnnotationAssertion( "XTWYTFMLZFPYCI-KQYNXXCUSA-L") -AnnotationAssertion( "425.18630") -AnnotationAssertion( "425.01486") -AnnotationAssertion( "Nc1ncnc2n(cnc12)[C@@H]1O[C@H](COP([O-])(=O)OP(O)([O-])=O)[C@@H](O)[C@H]1O") -AnnotationAssertion(Annotation( "Reaxys") "Reaxys:7558006") -AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "5'-O-{[(hydroxyphosphinato)oxy]phosphinato}adenosine") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion( "CHEBI:87518") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "ADP(2-)") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (receptor modulator) - -AnnotationAssertion( "A drug that acts as an antagonist, agonist, reverse agonist, or in some other fashion when interacting with cellular receptors.") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "ChEBI") "receptor modulators") -AnnotationAssertion( "CHEBI:90710") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "receptor modulator") -SubClassOf( ) - -# Class: (vasopressin) - -AnnotationAssertion( "A family of cyclic nonapeptide hormones found in most mammals. Synthesised in the hypothalamus and stored in the post-pituitary, vasopressins play a key role in homeostasis, particularly in regulating the body's water content. Together with the similar neuropeptide oxytocin, they are believed to influence social cognition and behaviour.") -AnnotationAssertion( "0") -AnnotationAssertion( "C46H65N15O12S2.C46H65N13O12S2") -AnnotationAssertion( "2140.458") -AnnotationAssertion( "2138.86956") -AnnotationAssertion(Annotation( "ChemIDplus") "CAS:11000-17-2") -AnnotationAssertion( "KEGG:C00840") -AnnotationAssertion( "KEGG:D00101") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:18988842") -AnnotationAssertion(Annotation( "Europe PMC") "PMID:20445498") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Vasopressin") -AnnotationAssertion( "chebi_ontology") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "ADH") -AnnotationAssertion(Annotation( "ChEBI") "AVP") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Antidiuretic hormone") -AnnotationAssertion(Annotation( "ChemIDplus") Annotation( ) "Inyectable de vasopresina") -AnnotationAssertion(Annotation( "ChemIDplus") Annotation( ) "Solute injectable de vasopressine") -AnnotationAssertion(Annotation( "KEGG_COMPOUND") "VP") -AnnotationAssertion(Annotation( "ChemIDplus") Annotation( ) "Vasopressini injectio") -AnnotationAssertion(Annotation( "ChEBI") "arginine vasopressin") -AnnotationAssertion(Annotation( "ChEBI") "argipressin") -AnnotationAssertion(Annotation( "ChemIDplus") "beta-Hypophamine") -AnnotationAssertion( "CHEBI:9937") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "vasopressin") -SubClassOf( ) -SubClassOf( ) - # Class: (cell) AnnotationAssertion(Annotation( "CARO:mah") "A material entity of anatomical origin (part of or deriving from an organism) that has as its parts a maximally connected cell compartment surrounded by a plasma membrane.") @@ -30686,29 +15148,10 @@ DisjointClasses( ) DisjointClasses( ) -# Class: (native cell) - -AnnotationAssertion(Annotation( "CARO:mah") "A cell that is found in a natural setting, which includes multicellular organism cells 'in vivo' (i.e. part of an organism), and unicellular organisms 'in environment' (i.e. part of a natural environment).") -AnnotationAssertion( "CARO:0000013") -AnnotationAssertion( "cell in vivo") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "To accommodate unicellular organisms better, 'cell in vivo' has been re-labeled 'native cell' to better represent its intended meaning - that is, that it is a cell in the context of a multicellular organism or in a natural environment. 'Native' is intended to contrast with 'in vitro', which refers to cells or other biological entities that have been intentionally placed in a controlled, non-natural setting for the purpose of study or manipulation. (MAH 1.12.12).") -AnnotationAssertion(rdfs:label "native cell") -SubClassOf( ) - -# Class: (fibroblast neural crest derived) - -AnnotationAssertion(Annotation( "https://orcid.org/0000-0001-5208-3432") "Any fibroblast that is deriived from the neural crest.") -AnnotationAssertion(rdfs:label "fibroblast neural crest derived") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (neuronal receptor cell) AnnotationAssertion( "neuronal receptor cell (sensu Animalia)") AnnotationAssertion(rdfs:label "neuronal receptor cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) # Class: (early embryonic cell (metazoa)) @@ -30729,16 +15172,6 @@ AnnotationAssertion(Annotation( "migratory trunk neural crest cell") SubClassOf( ) -# Class: (germ line stem cell) - -AnnotationAssertion(Annotation( "doi:10.1016/j.stem.2012.05.016") "A stem cell that is the precursor of gametes.") -AnnotationAssertion( "FBbt:00004861") -AnnotationAssertion( "germline stem cell") -AnnotationAssertion(rdfs:label "germ line stem cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) - # Class: (male germ cell) AnnotationAssertion(Annotation( "PMID:29462262") Annotation( "https://orcid.org/0000-0001-5208-3432") "A germ cell that supports male gamete production. In some species, non-germ cells known as Sertoli cells also play a role in spermatogenesis.") @@ -30751,21 +15184,6 @@ AnnotationAssertion(rdfs:seeAlso "ht SubClassOf(Annotation( "true") ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (spermatocyte) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "MESH:D013090") "A male germ cell that develops from spermatogonia. The euploid primary spermatocytes undergo meiosis and give rise to the haploid secondary spermatocytes which in turn give rise to spermatids.") -AnnotationAssertion( "BTO:0001275") -AnnotationAssertion( "CALOHA:TS-0951") -AnnotationAssertion( "EMAPA:31484") -AnnotationAssertion( "FBbt:00004936") -AnnotationAssertion( "FMA:84049") -AnnotationAssertion( "WBbt:0006799") -AnnotationAssertion(rdfs:label "spermatocyte") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (spermatid) AnnotationAssertion(Annotation( "MESH:D013087") "A male germ cell that develops from the haploid secondary spermatocytes. Without further division, spermatids undergo structural changes and give rise to spermatozoa.") @@ -30777,9 +15195,6 @@ AnnotationAssertion( "WBbt:0006800") AnnotationAssertion( "nematoblast") AnnotationAssertion(rdfs:label "spermatid") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) # Class: (sperm) @@ -30796,7 +15211,6 @@ AnnotationAssertion( "spermatozoon") AnnotationAssertion(rdfs:label "sperm") SubClassOf(Annotation( "true") ) -SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) # Class: (spermatogonium) @@ -30810,8 +15224,6 @@ AnnotationAssertion( "FMA:72291") AnnotationAssertion( "spermatogonial cell") AnnotationAssertion(rdfs:label "spermatogonium") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ) # Class: (female germ cell) @@ -30820,18 +15232,8 @@ AnnotationAssertion( "VHOG:0001530") AnnotationAssertion( "ncithesaurus:Egg") AnnotationAssertion(rdfs:label "female germ cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) -# Class: (female germ line stem cell) - -AnnotationAssertion(Annotation( "doi:10.1016/j.stem.2012.05.016") "A stem cell that is the precursor of female gametes.") -AnnotationAssertion( "FBbt:00004873") -AnnotationAssertion(rdfs:label "female germ line stem cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) - # Class: (oocyte) AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "ISBN:0721662544") "A female germ cell that has entered meiosis.") @@ -30847,16 +15249,6 @@ SubClassOf(Annotation( SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (oogonial cell) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "ISBN:0721662544") "An undifferentiated germ cell that proliferates rapidly and gives rise to oocytes.") -AnnotationAssertion( "FMA:83673") -AnnotationAssertion(rdfs:label "oogonial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (egg cell) AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "ISBN:0721662544") "A female gamete where meiosis has progressed to metaphase II and is able to participate in fertilization.") @@ -30871,32 +15263,14 @@ AnnotationAssertion( "ovum") AnnotationAssertion(rdfs:label "egg cell") AnnotationAssertion( "https://www.swissbiopics.org/api/image/Egg_cell.svg"^^xsd:anyURI) -SubClassOf( ) SubClassOf(Annotation( "true") ) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (smooth muscle cell neural crest derived) - -AnnotationAssertion(Annotation( "https://orcid.org/0000-0001-5208-3432") "A smooth muscle cell derived from the neural crest.") -AnnotationAssertion(rdfs:label "smooth muscle cell neural crest derived") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (neural crest derived neuron) - -AnnotationAssertion( "neuron neural crest derived") -AnnotationAssertion(rdfs:label "neural crest derived neuron") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (glioblast) AnnotationAssertion(rdfs:label "glioblast") SubClassOf( ) -SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) # Class: (neuroblast (sensu Vertebrata)) @@ -30920,8 +15294,6 @@ AnnotationAssertion( ) AnnotationAssertion(rdfs:comment "This term applies to metazoan. For plant stem cells, consider using PO:0004011 ‘initial cell’ or its parent PO:0004010 ‘meristematic cell’.") AnnotationAssertion(rdfs:label "stem cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) @@ -30932,7 +15304,6 @@ AnnotationAssertion( "unipotent stem cell") AnnotationAssertion( "unipotential stem cell") AnnotationAssertion(rdfs:label "single fate stem cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf( ) # Class: (epithelial fate stem cell) @@ -30961,7 +15332,6 @@ AnnotationAssertion( ) AnnotationAssertion(rdfs:comment "Markers differ between species, and two sets of markers have been described for mice. HSCs are reportedly CD34-positive, CD45-positive, CD48-negative, CD150-positive, CD133-positive, and CD244-negative.") AnnotationAssertion(rdfs:label "hematopoietic stem cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) @@ -30989,9 +15359,8 @@ AnnotationAssertion( ) AnnotationAssertion(rdfs:comment "Originally this term had some plant germ line cell children.") AnnotationAssertion(rdfs:label "germ line cell") -SubClassOf( ) +SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -DisjointClasses( ) # Class: (monoblast) @@ -31004,7 +15373,6 @@ AnnotationAssertion( "monocyte stem cell") AnnotationAssertion(rdfs:comment "Morphology: mononuclear cell, diameter 12-20 _M, non-granular, N/C ratio 3/1 - 4/1; markers: CD11b (shared with many other myeloid cells); location: Adult: bone marrow; fetal: liver, Yolk Sac; role or process: hematopoiesis, monocyte development; lineage: hematopoietic, myeloid.") AnnotationAssertion(rdfs:label "monoblast") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) SubClassOf( ObjectSomeValuesFrom( )) @@ -31017,7 +15385,6 @@ AnnotationAssertion( "multipotent cell") AnnotationAssertion( "multipotent stem cell") AnnotationAssertion(rdfs:label "multi fate stem cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) # Class: (common myeloid progenitor) @@ -31054,7 +15421,6 @@ AnnotationAssertion( ) AnnotationAssertion(rdfs:comment "MEPs are reportedly CD19-negative, CD34-negative, CD45RA-negative, CD110-positive, CD117-positive, and SCA1-negative and reportedly express the transcription factors GATA-1 and NF-E2.") AnnotationAssertion(rdfs:label "megakaryocyte-erythroid progenitor cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) SubClassOf( ObjectSomeValuesFrom( )) DisjointClasses( ) @@ -31076,7 +15442,6 @@ AnnotationAssertion( ) AnnotationAssertion(rdfs:comment "CLP are CD7-positive, CD10-positive, CD19-negative, CD34-positive, CD45RA-positive, CD79a-negative, CD127-positive, AA4.1-positive, RAG-negative, Sca-1-low, sIgM-negative, sIgD-negative, TdT-negative, Vpre-B-negative, and pre-BCR-negative. Expression of transcription factors include E2A-positive, EBF-positive, Ikaros-negative, PU.1-negative, and Pax5-negative.") AnnotationAssertion(rdfs:label "common lymphoid progenitor") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) # Class: (totipotent stem cell) @@ -31096,7 +15461,7 @@ AnnotationAssertion( "blast cell") AnnotationAssertion(rdfs:comment "define using PATO mulit-potent or oligopotent?") AnnotationAssertion(rdfs:label "non-terminally differentiated cell") -SubClassOf( ) +SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) # Class: (myoblast) @@ -31108,7 +15473,6 @@ AnnotationAssertion( "FMA:70335") AnnotationAssertion( "VHOG:0001529") AnnotationAssertion(rdfs:label "myoblast") -SubClassOf( ) SubClassOf( ) # Class: (fibroblast) @@ -31185,14 +15549,6 @@ SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (ciliated cell) - -AnnotationAssertion(Annotation( "GOC:tfm") "A cell that has a filiform extrusion of the cell surface.") -AnnotationAssertion( "VHOG:0001532") -AnnotationAssertion( "XAO:0000031") -AnnotationAssertion(rdfs:label "ciliated cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (ependymal cell) AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "JB:jb") Annotation( "PMID:9550134") "A neurectoderm derived cell that lines the neural lumen.") @@ -31220,7 +15576,7 @@ AnnotationAssertion( ) AnnotationAssertion(rdfs:label "epithelial cell") AnnotationAssertion( "https://www.swissbiopics.org/api/image/Epithelial_cells.svg"^^xsd:anyURI) -SubClassOf( ) +SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) DisjointClasses( ) @@ -31229,15 +15585,12 @@ DisjointClasses( "GOC:tfm") "An epithelial cell that has a cilia.") AnnotationAssertion( "FMA:70605") AnnotationAssertion(rdfs:label "ciliated epithelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (duct epithelial cell) AnnotationAssertion(Annotation( "https://orcid.org/0000-0001-5208-3432") "An epithelial cell that is part of a duct.") AnnotationAssertion(rdfs:label "duct epithelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -SubClassOf( ) # Class: (branched duct epithelial cell) @@ -31251,18 +15604,10 @@ AnnotationAssertion( "cuboidal endothelial cell of vascular tree") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "blood vessel endothelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) SubClassOf( ) -SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (non-branched duct epithelial cell) - -AnnotationAssertion(rdfs:label "non-branched duct epithelial cell") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (columnar/cuboidal epithelial cell) AnnotationAssertion(Annotation( "GO:0002065") Annotation( "https://orcid.org/0000-0001-5208-3432") "A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube.") @@ -31270,7 +15615,6 @@ AnnotationAssertion( ) AnnotationAssertion(rdfs:label "columnar/cuboidal epithelial cell") SubClassOf( ) -SubClassOf( ) # Class: (squamous epithelial cell) @@ -31294,15 +15638,8 @@ SubClassOf( ObjectSomeValuesFrom( "stratified epithelial cell") SubClassOf( ) -SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (circulating cell) - -AnnotationAssertion(Annotation( "GOC:add") "A cell which moves among different tissues of the body, via blood, lymph, or other medium.") -AnnotationAssertion(rdfs:label "circulating cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (blood cell) AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:tfm") "A cell found predominately in the blood.") @@ -31310,7 +15647,6 @@ AnnotationAssertion( "MESH:D001773") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "blood cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) # Class: (epithelial cell of lung) @@ -31321,7 +15657,6 @@ AnnotationAssertion( "lung epithelial cell") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "epithelial cell of lung") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ObjectSomeValuesFrom( )) # Class: (epithelial cell of pancreas) @@ -31331,9 +15666,6 @@ AnnotationAssertion( "pancreas epithelial cell") AnnotationAssertion( "pancreatic epithelial cell") AnnotationAssertion(rdfs:label "epithelial cell of pancreas") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) # Class: (T cell) @@ -31353,42 +15685,10 @@ AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "T cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) SubClassOf( ObjectSomeValuesFrom( )) DisjointClasses( ) -# Class: (osteoclast) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:tfm") Annotation( "GO_REF:0000031") Annotation( "ISBN:0781735149") Annotation( "PMID:10428500") Annotation( "PMID:15055519") Annotation( "PMID:17380158") "A specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue, which typically differentiates from monocytes. This cell has the following markers: tartrate-resistant acid phosphatase type 5-positive, PU.1-positive, c-fos-positive, nuclear factor NF-kappa-B p100 subunit-positive, tumor necrosis factor receptor superfamily member 11A-positive and macrophage colony-stimulating factor 1 receptor-positive.") -AnnotationAssertion( "BTO:0000968") -AnnotationAssertion( "CALOHA:TS-0721") -AnnotationAssertion( "FMA:66781") -AnnotationAssertion( "MESH:D010010") -AnnotationAssertion( "chondroclast") -AnnotationAssertion(rdfs:comment "Morphology: Highly vesicular; markers: Surface: RANK, cFMS (MCSF receptor); Secreted: cathepsin K and TRAP (tartate resistant acid phosphatase); transcription factors: PU.1, cFOS, MITF, NFkB (p52); role or process: tissue remodelling: bone resorption; lineage: hematopoietic, myeloid.") -AnnotationAssertion(rdfs:label "osteoclast") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (granulocyte) - -AnnotationAssertion(Annotation( "GOC:amm") Annotation( "GOC:tfm") Annotation( "MESH:D006098") Annotation( "http://en.wikipedia.org/wiki/Granulocyte") "A leukocyte with abundant granules in the cytoplasm.") -AnnotationAssertion( ) -AnnotationAssertion( "BTO:0000539") -AnnotationAssertion( "BTO:0001026") -AnnotationAssertion( "CALOHA:TS-0422") -AnnotationAssertion( "FMA:62854") -AnnotationAssertion( "granular leucocyte") -AnnotationAssertion( "granular leukocyte") -AnnotationAssertion( "polymorphonuclear leukocyte") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "granulocyte") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - # Class: (neuron associated cell) AnnotationAssertion(rdfs:label "neuron associated cell") @@ -31402,10 +15702,7 @@ AnnotationAssertion( "BTO:0004301") AnnotationAssertion(rdfs:comment "The term \"neuroepithelial cell\" is used to describe both this cell type and neurecto-epithelial cell (CL:0000710).") AnnotationAssertion(rdfs:label "sensory epithelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) SubClassOf( ) -SubClassOf( ) # Class: (interneuron) @@ -31441,31 +15738,13 @@ AnnotationAssertion( "MESH:D011984") AnnotationAssertion( "WBbt:0005759") AnnotationAssertion(rdfs:label "sensory neuron") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (bipolar neuron) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "ISBN:0444009442") "A type of interneuron that has two neurites, usually an axon and a dendrite, extending from opposite poles of an ovoid cell body.") -AnnotationAssertion( "FMA:67282") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "bipolar neuron") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (multipolar neuron) - -AnnotationAssertion(Annotation( "FMA:67287") Annotation( "GOC:tfm") "A neuron with three or more neurites, usually an axon and multiple dendrites.") -AnnotationAssertion( "FMA:67287") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "multipolar neuron") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (autonomic neuron) AnnotationAssertion(Annotation( "GOC:tfm") "A neuron whose cell body is within an autonomic ganglion.") AnnotationAssertion( "FMA:80121") AnnotationAssertion(rdfs:label "autonomic neuron") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) # Class: (cholinergic neuron) @@ -31477,7 +15756,6 @@ AnnotationAssertion( "MESH:D059329") AnnotationAssertion( "WBbt:0006840") AnnotationAssertion(rdfs:label "cholinergic neuron") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (surface ectodermal cell) @@ -31514,7 +15792,6 @@ AnnotationAssertion(Annotation( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "basket cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) # Class: (cerebellar Golgi cell) @@ -31528,13 +15805,6 @@ AnnotationAssertion(rdfs:label "cere SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (granule cell) - -AnnotationAssertion(Annotation( ) "A neuron of the vertebrate central nervous system that is small in size. This general class includes small neurons in the granular layer of the cerebellar cortex, cerebral cortex neurons that are not pyramidal cells and small neurons without axons found in the olfactory bulb.") -AnnotationAssertion( "BTO:0003393") -AnnotationAssertion(rdfs:label "granule cell") -SubClassOf( ) - # Class: (Purkinje cell) AnnotationAssertion(Annotation( "MESH:D011689") "The output neuron of the cerebellar cortex.") @@ -31556,7 +15826,6 @@ AnnotationAssertion(Annotation( "BTO:0002316") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "stellate neuron") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (neuron associated cell (sensu Vertebrata)) @@ -31586,7 +15855,7 @@ AnnotationAssertion( "CALOHA:TS-2027") AnnotationAssertion( "FMA:54538") AnnotationAssertion( "macrogliocyte") -AnnotationAssertion(Annotation( "doi:10.1152/physrev.2001.81.2.871") Annotation( ) "macroglia") +AnnotationAssertion(Annotation( "doi:10.1152/physrev.2001.81.2.871") Annotation( ) "macroglia") AnnotationAssertion(rdfs:label "macroglial cell") SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) @@ -31604,23 +15873,6 @@ AnnotationAssertion(rdfs:comment "As AnnotationAssertion(rdfs:label "astrocyte") SubClassOf( ) -# Class: (oligodendrocyte) - -AnnotationAssertion(Annotation( "MESH:D009836") Annotation( "http://en.wikipedia.org/wiki/Oligodendrocyte") "A class of large neuroglial (macroglial) cells in the central nervous system. Form the insulating myelin sheath of axons in the central nervous system.") -AnnotationAssertion( ) -AnnotationAssertion( "BTO:0000962") -AnnotationAssertion( "CALOHA:TS-0709") -AnnotationAssertion( "FMA:54540") -AnnotationAssertion(Annotation( "PMID:8734446") "OLs") -AnnotationAssertion( "oligodendroglia") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "Oligodendrocytes are reportedly MDP-positive and CD4-negative.") -AnnotationAssertion(rdfs:label "oligodendrocyte") -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (neurectodermal cell) AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "ISBN:068340007X") "Ectoderm destined to be nervous tissue.") @@ -31641,11 +15893,11 @@ AnnotationAssertion(Annotation( ) "CFU-F") AnnotationAssertion(Annotation( "PMID:11378515") Annotation( ) "MSC") AnnotationAssertion( "mesenchymal precursor cell") -AnnotationAssertion(Annotation( "MESH:D044982") Annotation( ) "mesenchymal progenitor cells") +AnnotationAssertion(Annotation( "MESH:D044982") Annotation( ) "mesenchymal progenitor cells") AnnotationAssertion( "mesenchymal stem cell") AnnotationAssertion( "mesenchymal stromal cell") -AnnotationAssertion(Annotation( ) "mesenchymal stromal cells") -AnnotationAssertion(Annotation( "MESH:D044982") Annotation( ) "stem cells, mesenchymal") +AnnotationAssertion(Annotation( ) "mesenchymal stromal cells") +AnnotationAssertion(Annotation( "MESH:D044982") Annotation( ) "stem cells, mesenchymal") AnnotationAssertion(rdfs:comment "Many but not all mesenchymal cells derive from the mesoderm. MSCs are reportedly CD3-negative, CD4-negative, CD5-negative, CD8-negative, CD11a-negative, CD11b-negative, CD14-negative, CD19-negative, CD29-positive, CD31-negative, CD34-negative, CD38-negative, CD40-negative, CD44-positive, CD45-negative, CD49-positive, CD54-positive, CD66b-negative, CD79a-negative, CD80-negative, CD102-positive, CD106-positive, CD117-positive, CD121a-positive, CD121b-positive, CD123-positive, CD124-positive, CD133-negative, CD146-positive, CD166-positive, CD271-positive, B220-negative, Gr1-negative, MHCI-positive, MHCII-negative, SSEA4-negative, sca1-positive, Ter119-negative, and glycophorin A-negative. Cultured MSCs are capable of producing stem cell factor, IL7, IL8, IL11, TGF-beta, cofilin, galectin-1, laminin-receptor 1, cyclophilin A, and MMP-2.") AnnotationAssertion(rdfs:label "mesenchymal stem cell") AnnotationAssertion(rdfs:seeAlso "https://github.com/obophenotype/cell-ontology/issues/474") @@ -31658,7 +15910,6 @@ AnnotationAssertion(Annotation( "FMA:63879") AnnotationAssertion(rdfs:comment "Cultured human fibrocytes are MHCI-positive, MHCII-positive, CD1a-negative, CD3-negative, CD4-negative, CD8-negative, CD10-negative, CD11b-positive, CD13-positive, CD14-negative, CD16-negative, CD18-positive, CD19-negative, CD25-negative, CD29-positive, CD32-positive, CD33-negative, CD34-positive, CD38-negative, CD40-positive, CD44-negative, CD45RO-positive, CD49a-positive, CD49b-positive, CD49c-negative, CD49d-negative, CD49e-positive, CD49f-negative, CD56-negative, CD58-positive, CD61-positive, CD64-positive, CD70-negative, CD71-positive, CD80-positive, CD83-negative, CD86-positive, CD103-negative, CD105-positive, CD181-positive, CD182-negative, CD183-positive, CD184-positive, CD185-negative, CD186-negative, CD191-positive, CD192-negative, CD193-positive, CD194-positive, CD195-positive, CD196-negative, CD197-positive, CD199-positive, desmin-negative, F4/80-positive, Gr1-positive, LSP-1-positive, MHCI-positive, MHCII-positive, alpha-SMA-negative, TCRab-negative, TCRgd-negative, and vimentin-positive. Fibrocytes are also capable of secreting angiogenin, bFGF, CCL2, CCL3, CCL4, CCL8, CXCL1, type I collagen, type III collagen, CTGF, fibronectin, GM-CSF, IL-1a, IL-6, IL-8, IL-10, M-CSF, MMP-9, PDGF-A, TGF-alpha, TGF-beta1, TNF-alpha, and VEGF-A.") AnnotationAssertion(rdfs:label "fibrocyte") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) SubClassOf( ObjectSomeValuesFrom( )) @@ -31706,16 +15957,6 @@ SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (professional antigen presenting cell) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") "A cell capable of processing and presenting lipid and protein antigens to T cells in order to initiate an immune response.") -AnnotationAssertion(Annotation( ) "APC") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "Note change of name; nearly all somatic cells can present antigens to T cells via MHC Class I complexes leading to effector responses, but professional antigen presenting cells constitutively express MHC Class II as well as costimulatory molecules, and thus can initiate immune responses via T cells.") -AnnotationAssertion(rdfs:label "professional antigen presenting cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - # Class: (simple columnar epithelial cell) AnnotationAssertion( ) @@ -31745,17 +15986,12 @@ AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "melanocyte") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) -SubClassOf( ) # Class: (visual pigment cell) AnnotationAssertion( "pigment cell") AnnotationAssertion(rdfs:label "visual pigment cell") SubClassOf( ) -SubClassOf( ) # Class: (glandular epithelial cell) @@ -31765,7 +16001,6 @@ AnnotationAssertion( "glandular epithelial cell") SubClassOf( ) SubClassOf( ) -SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) # Class: (secretory cell) @@ -31776,17 +16011,6 @@ AnnotationAssertion( "FMA:86916") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "secretory cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (exocrine cell) - -AnnotationAssertion(Annotation( "ISBN:0198547684") "A cell of an exocrine gland; i.e. a gland that discharges its secretion via a duct.") -AnnotationAssertion( "FMA:16014") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "exocrine cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) # Class: (glycosaminoglycan secreting cell) @@ -31800,7 +16024,6 @@ SubClassOf( (protein secreting cell) AnnotationAssertion(rdfs:label "protein secreting cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (peptic cell) @@ -31815,13 +16038,6 @@ SubClassOf( ) SubClassOf( ) -# Class: (surfactant secreting cell) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "ISBN:0721662544") "A cell that specializes in secretion of surfactant in the alveoli of the lung.") -AnnotationAssertion(rdfs:label "surfactant secreting cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - # Class: (club cell) AnnotationAssertion(Annotation( "DOI:10.1183/09031936.00146609") Annotation( "DOI:10.1378/chest.12-2762") Annotation( "GOC:tfm") Annotation( "PMID:28128362") Annotation( "PMID:29874100") Annotation( "PMID:7905712") "A non-mucous, epithelial secretory cell that is part of the tracheobronchial tree. A club cell has short microvilli but no cilia. A club cell is able to multiply and differentiate into ciliated cells to regenerate the bronchiolar epithelium and it also protects the tracheobronchial epithelium.") @@ -31874,8 +16090,6 @@ AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "endocrine cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))))) -SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) # Class: (enteroendocrine cell) @@ -31902,7 +16116,6 @@ AnnotationAssertion(Annotation( "neuroendocrine cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ) @@ -31921,94 +16134,19 @@ SubClassOf( ObjectSomeValuesFrom( (peptide hormone secreting cell) AnnotationAssertion(rdfs:label "peptide hormone secreting cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (insulin secreting cell) AnnotationAssertion( "BTO:0000783") AnnotationAssertion(rdfs:label "insulin secreting cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (type B pancreatic cell) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "ISBN:0517223651") Annotation( "http://en.wikipedia.org/wiki/Pancreatic_b_cell") "A cell that secretes insulin and is located towards the center of the islets of Langerhans.") -AnnotationAssertion( ) -AnnotationAssertion(Annotation( "ZFA:0009102") "beta cell") -AnnotationAssertion( "BTO:0000783") -AnnotationAssertion( "EV:0200009") -AnnotationAssertion( "FMA:70586") -AnnotationAssertion( "MA:0002419") -AnnotationAssertion( "ncithesaurus:Beta_Cell") -AnnotationAssertion(Annotation( "FMA:70586") "B-cell of pancreatic islet") -AnnotationAssertion(Annotation( "FMA:70586") "beta cell of pancreatic islet") -AnnotationAssertion(Annotation( "FMA:70586") "insulin-secreting cell") -AnnotationAssertion( "pancreatic B cell") -AnnotationAssertion(Annotation( "FMA:70586") "pancreatic B-cell") -AnnotationAssertion(Annotation( "FMA:70586") "pancreatic beta cell") -AnnotationAssertion(Annotation( "MA:0002419") "pancreatic islet core") -AnnotationAssertion(Annotation( "FMA:70586") "type B enteroendocrine cell") -AnnotationAssertion(Annotation( "MA:0002419") "beta cell islet") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "Pancreatic beta cells are also reportedly CD284-positive. Upon activation, they upregulate their CD14 expression.") -AnnotationAssertion(rdfs:label "type B pancreatic cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (glucagon secreting cell) - -AnnotationAssertion(Annotation( "GOC:tfm") "A cell that secretes glucagon.") -AnnotationAssertion( "FMA:84045") -AnnotationAssertion( "glucagon-secreting cell") -AnnotationAssertion(rdfs:label "glucagon secreting cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (pancreatic A cell) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "ISBN:0721662544") "A type of enteocrine cell found in the periphery of the islets of Langerhans that secretes glucagon.") -AnnotationAssertion( ) -AnnotationAssertion( "BTO:0000990") -AnnotationAssertion( "FMA:70585") -AnnotationAssertion( "MESH:D050416") -AnnotationAssertion( "alpha cell of islet of Langerhans") -AnnotationAssertion( "pancreatic alpha cell") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "pancreatic A cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) # Class: (somatostatin secreting cell) AnnotationAssertion(rdfs:label "somatostatin secreting cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (pancreatic D cell) - -AnnotationAssertion(Annotation( "FMA:0517223651") Annotation( "GOC:tfm") "A D cell located in the pancreas. Peripherally placed within the islets like type A cells; contains somatostatin.") -AnnotationAssertion( ) -AnnotationAssertion( "BTO:0000803") -AnnotationAssertion( "FMA:70587") -AnnotationAssertion( "D-cell of pancreatic islet") -AnnotationAssertion( "delta cell of islet") -AnnotationAssertion( "delta cell of pancreatic islet") -AnnotationAssertion( "pancreatic D-cell") -AnnotationAssertion( "pancreatic delta cell") -AnnotationAssertion( "somatostatin-secreting pancreatic cell") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "pancreatic D cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) # Class: (steroid hormone secreting cell) AnnotationAssertion(rdfs:label "steroid hormone secreting cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (luteal cell) @@ -32016,6 +16154,7 @@ AnnotationAssertion(Annotation( ) AnnotationAssertion( "BTO:0003939") AnnotationAssertion( "FMA:18688") +AnnotationAssertion(Annotation( "PMID:16790079") "corpus luteum cell") AnnotationAssertion( "lutein cell") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "luteal cell") @@ -32027,7 +16166,6 @@ SubClassOf( ObjectSomeValuesFrom( (testosterone secreting cell) AnnotationAssertion(rdfs:label "testosterone secreting cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (Leydig cell) @@ -32042,15 +16180,9 @@ AnnotationAssertion( "Note that the Amphibian Anatomy Ontology (AA) has a class 'leydig cells' but this is unrelated") AnnotationAssertion(rdfs:label "Leydig cell") SubClassOf( ) -SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (progesterone secreting cell) - -AnnotationAssertion(rdfs:label "progesterone secreting cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (hepatocyte) AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "ISBN:0412046911") Annotation( "MESH:D022781") Annotation( "PMID:19717280") Annotation( "http://en.wikipedia.org/wiki/Hepatocyte") "The main structural component of the liver. They are specialized epithelial cells that are organized into interconnected plates called lobules. Majority of cell population of liver, polygonal in shape, arranged in plates or trabeculae between sinusoids; may have single nucleus or binucleated.") @@ -32063,7 +16195,6 @@ AnnotationAssertion(rdfs:comment "He AnnotationAssertion(rdfs:label "hepatocyte") SubClassOf( ) SubClassOf( ) -SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) @@ -32074,7 +16205,7 @@ SubClassOf( ObjectSomeValuesFrom( "FB:ma") "A cell whose primary function is to shorten.") AnnotationAssertion(rdfs:label "contractile cell") -SubClassOf( ) +SubClassOf( ) # Class: (myoepithelial cell) @@ -32087,7 +16218,6 @@ AnnotationAssertion( "myoepithelial cell") SubClassOf( ) SubClassOf( ) -SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) # Class: (muscle cell) @@ -32105,8 +16235,6 @@ AnnotationAssertion(rdfs:label "musc AnnotationAssertion( "https://www.swissbiopics.org/api/image/Muscle_cells.svg"^^xsd:anyURI) SubClassOf( ) SubClassOf( ) -SubClassOf( ) -SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) # Class: (cell of skeletal muscle) @@ -32120,8 +16248,6 @@ AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "cell of skeletal muscle") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) # Class: (slow muscle cell) @@ -32164,8 +16290,6 @@ AnnotationAssertion( "MESH:D011984") AnnotationAssertion( "receptor cell") AnnotationAssertion(rdfs:label "sensory receptor cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ) # Class: (pain receptor cell) @@ -32181,12 +16305,6 @@ SubClassOf( "MESH:D008465") "A cell specialized to transduce mechanical stimuli and relay that information centrally in the nervous system.") AnnotationAssertion(Annotation( "MP:0000972") "mechanoreceptor") AnnotationAssertion(rdfs:label "mechanoreceptor cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (touch receptor cell) - -AnnotationAssertion(rdfs:label "touch receptor cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (auditory hair cell) @@ -32202,7 +16320,6 @@ SubClassOf( ObjectSomeValuesFrom( "MESH:D002628") "A cell specialized to detect chemical substances and relay that information centrally in the nervous system. Chemoreceptors may monitor external stimuli, as in taste and olfaction, or internal stimuli, such as the concentrations of oxygen and carbon dioxide in the blood.") AnnotationAssertion(rdfs:label "chemoreceptor cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (olfactory receptor cell) @@ -32215,7 +16332,6 @@ AnnotationAssertion( "olfactory receptor neuron") AnnotationAssertion( "olfactory sensory neuron") AnnotationAssertion(rdfs:label "olfactory receptor cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ObjectSomeValuesFrom( )) # Class: (taste receptor cell) @@ -32224,7 +16340,6 @@ AnnotationAssertion(Annotation( "FMA:67910") AnnotationAssertion( "taste bud cell") AnnotationAssertion(rdfs:label "taste receptor cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) @@ -32236,14 +16351,13 @@ AnnotationAssertion( "FMA:86740") AnnotationAssertion(rdfs:label "photoreceptor cell") AnnotationAssertion( "https://www.swissbiopics.org/api/image/Photoreceptor_cell.svg"^^xsd:anyURI) -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) # Class: (electrically active cell) AnnotationAssertion(Annotation( "FB:ma") "A cell whose function is determined by the generation or the reception of an electric signal.") AnnotationAssertion(rdfs:label "electrically active cell") -SubClassOf( ) +SubClassOf( ) # Class: (lining cell) @@ -32266,7 +16380,7 @@ SubClassOf( ObjectSomeValuesFrom( "JB:jb") "A cell whose primary function is to prevent the transport of stuff across compartments.") AnnotationAssertion(rdfs:label "barrier cell") -SubClassOf( ) +SubClassOf( ) # Class: (Sertoli cell) @@ -32276,36 +16390,15 @@ AnnotationAssertion( "FMA:72298") AnnotationAssertion( "VHOG:0001348") AnnotationAssertion(rdfs:label "Sertoli cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf(Annotation( "true") ) SubClassOf( ) -# Class: (insulating cell) - -AnnotationAssertion(rdfs:label "insulating cell") -SubClassOf( ) - -# Class: (myelinating Schwann cell) - -AnnotationAssertion(Annotation( "GOC:cvs") Annotation( "GOC:tfm") Annotation( "MESH:D012583") "A neuroglial cell of the peripheral nervous system which forms the insulating myelin sheaths of peripheral axons.") -AnnotationAssertion( "Schwann cell") -AnnotationAssertion( "peripheral neuroglial cell") -AnnotationAssertion( "CALOHA:TS-0898") -AnnotationAssertion( "FMA:62121") -AnnotationAssertion( "neurilemmal cell") -AnnotationAssertion(rdfs:label "myelinating Schwann cell") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (motile cell) AnnotationAssertion(Annotation( "FB:ma") "A cell that moves by its own activities.") AnnotationAssertion(rdfs:label "motile cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (ectodermal cell) @@ -32341,19 +16434,6 @@ AnnotationAssertion(Annotation( "FMA:68647") AnnotationAssertion( "non-nucleated cell") AnnotationAssertion(rdfs:label "anucleate cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -DisjointClasses( ) - -# Class: (single nucleate cell) - -AnnotationAssertion(Annotation( "FB:ma") Annotation( "GOC:tfm") "A cell with a single nucleus.") -AnnotationAssertion(rdfs:label "single nucleate cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (binucleate cell) - -AnnotationAssertion(rdfs:label "binucleate cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (multinucleate cell) @@ -32364,7 +16444,6 @@ AnnotationAssertion( "syncytial cell") AnnotationAssertion( "syncytium") AnnotationAssertion(rdfs:label "multinucleate cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (erythrocyte) @@ -32378,7 +16457,6 @@ AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "erythrocyte") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) SubClassOf( ObjectSomeValuesFrom( )) @@ -32411,11 +16489,9 @@ AnnotationAssertion( "FMA:83806") AnnotationAssertion( "MESH:D010586") AnnotationAssertion(rdfs:label "phagocyte") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ) -SubClassOf( ) # Class: (macrophage) @@ -32432,7 +16508,6 @@ AnnotationAssertion( ) AnnotationAssertion(rdfs:comment "Morphology: Diameter 30_M-80 _M, abundant cytoplasm, low N/C ratio, eccentric nucleus. Irregular shape with pseudopods, highly adhesive. Contain vacuoles and phagosomes, may contain azurophilic granules; markers: Mouse & Human: CD68, in most cases CD11b. Mouse: in most cases F4/80+; role or process: immune, antigen presentation, & tissue remodelling; lineage: hematopoietic, myeloid.") AnnotationAssertion(rdfs:label "macrophage") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) SubClassOf( ObjectSomeValuesFrom( )) @@ -32452,7 +16527,6 @@ AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "B cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) SubClassOf( ObjectSomeValuesFrom( )) @@ -32463,12 +16537,6 @@ SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (brush border epithelial cell) - -AnnotationAssertion(rdfs:label "brush border epithelial cell") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (stratified squamous epithelial cell) AnnotationAssertion( ) @@ -32489,50 +16557,20 @@ SubClassOf( "PMID:19782676") ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (transitional epithelial cell) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "ISBN:0721662544") "A cell characteristically found lining hollow organs that are subject to great mechanical change due to contraction and distention; originally thought to represent a transition between stratified squamous and columnar epithelium.") -AnnotationAssertion( ) -AnnotationAssertion( "FMA:66778") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "transitional epithelial cell") -SubClassOf( ) -SubClassOf( ) - -# Class: (eukaryotic cell) - -AnnotationAssertion( "MESH:D005057") -AnnotationAssertion(rdfs:label "eukaryotic cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (Eumycetozoan cell) - -AnnotationAssertion(rdfs:label "Eumycetozoan cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - # Class: (eye photoreceptor cell) AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "eye photoreceptor cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (structural cell) - -AnnotationAssertion(Annotation( "TAIR:sr") "A cell whose primary function is to provide structural support, to provide strength and physical integrity to the organism.") -AnnotationAssertion(rdfs:label "structural cell") -SubClassOf( ) - # Class: (somatotropin secreting cell) AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "SANBI:mhl") "A peptide hormone secreting cell that produces growth hormone, somatotropin.") AnnotationAssertion( "growth hormone secreting cell") AnnotationAssertion( "somatotrophin secreting cell") AnnotationAssertion(rdfs:label "somatotropin secreting cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (gamete) @@ -32543,7 +16581,6 @@ AnnotationAssertion( "haploid nucleated cell") AnnotationAssertion( "haploid germ cell") AnnotationAssertion(rdfs:label "gamete") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) # Class: (crystallin accumulating cell) @@ -32553,19 +16590,6 @@ AnnotationAssertion( "crystallin accumulating cell") SubClassOf( ) -# Class: (tracheal epithelial cell) - -AnnotationAssertion(Annotation( "GOC:tfm") "An epithelial cell found in the trachea.") -AnnotationAssertion( ) -AnnotationAssertion( "FMA:74793") -AnnotationAssertion( "tracheocyte") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "This class is for the vertebrate tracheal structure. For the analagous insect cell type, see 'respiratory tube epithelial cell'") -AnnotationAssertion(rdfs:label "tracheal epithelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (keratin accumulating cell) AnnotationAssertion(rdfs:label "keratin accumulating cell") @@ -32583,7 +16607,6 @@ AnnotationAssertion( ) AnnotationAssertion(rdfs:comment "Keratinocytes are reportedly CDw210a-negative, CDw210b-positive, CD281-positive, CD282-positive, CD285-positive, IL22Ra1-positive, Human keratinocytes are reportedly capable of secreting BD-2, BD-3, hCAP-18, CXCL1, CXCL5, CXCL8, elafin, MMP-3, NGAL, PDGF-A, S100A7, S100A8, and S100A9. Transcription factors: STAT3-positive.") AnnotationAssertion(rdfs:label "keratinocyte") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) SubClassOf(Annotation( "true") ) SubClassOf( ObjectSomeValuesFrom( )) @@ -32599,27 +16622,11 @@ AnnotationAssertion( "serous secreting cell") SubClassOf( ) -# Class: (milk secreting cell) - -AnnotationAssertion(rdfs:label "milk secreting cell") -SubClassOf( ) - -# Class: (sebum secreting cell) - -AnnotationAssertion(Annotation( "MESH:D012629") "A cell secreting sebun, an oily substance secreted by sebaceous glands, composed of keratin, fat, and cellular debris.") -AnnotationAssertion( ) -AnnotationAssertion( "sebocyte") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "sebum secreting cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - # Class: (mucus secreting cell) AnnotationAssertion( "BTO:0003689") AnnotationAssertion( "mucous cell") AnnotationAssertion(rdfs:label "mucus secreting cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) @@ -32640,24 +16647,19 @@ SubClassOf( ObjectSomeValuesFrom( "FB:ma") "A cell that is specialised to accumulate a particular substance(s).") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "stuff accumulating cell") -SubClassOf( ) +SubClassOf( ) # Class: (extracellular matrix secreting cell) AnnotationAssertion(rdfs:label "extracellular matrix secreting cell") SubClassOf( ) -# Class: (oxygen accumulating cell) - -AnnotationAssertion(rdfs:label "oxygen accumulating cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (migratory neural crest cell) AnnotationAssertion(Annotation( "doi:10.1016/j.stem.2015.02.017") "A cell derived from the specialized ectoderm flanking each side of the embryonic neural plate, which after the closure of the neural tube, forms masses of cells that migrate out from the dorsal aspect of the neural tube to spread throughout the body.") AnnotationAssertion( "FMA:86667") AnnotationAssertion(rdfs:label "migratory neural crest cell") -SubClassOf( ) +SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) @@ -32666,7 +16668,6 @@ SubClassOf( ObjectSomeValuesFrom( "GOC:tfm") Annotation( "PMID:5025404") "A mesenchymal cell in embryonic development found in a contracting mass and that gives rise to osteoprogenitors.") AnnotationAssertion(rdfs:label "mesenchyme condensation cell") -SubClassOf( ) SubClassOf( ) # Class: (adrenal medulla chromaffin cell) @@ -32675,7 +16676,6 @@ AnnotationAssertion(Annotation( "FMA:69262") AnnotationAssertion(Annotation( "FMA:69262") "medullary chromaffin cell of adrenal gland") AnnotationAssertion(rdfs:label "adrenal medulla chromaffin cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) SubClassOf(Annotation( "true") ) SubClassOf( ) @@ -32691,44 +16691,17 @@ SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (hair follicle dermal papilla cell) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:9893172") "A specialized mesenchymal cell that resides in the dermal papilla located at the bottom of hair follicles. This cell plays a pivotal roles in hair formation, growth, and cycling.") -AnnotationAssertion(rdfs:comment "Are these really all stem cells?") -AnnotationAssertion(rdfs:label "hair follicle dermal papilla cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (scleral cell) AnnotationAssertion(Annotation( "GOC:add") "A cell of the sclera of the eye.") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "scleral cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (choroidal cell of the eye) - -AnnotationAssertion(Annotation( "GOC:add") "A structural cell that is part of optic choroid.") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "choroidal cell of the eye") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (extraembryonic cell) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "extraembryonic cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (amnioserosal cell) - -AnnotationAssertion(rdfs:label "amnioserosal cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (trophoblast cell) @@ -32767,7 +16740,6 @@ AnnotationAssertion(Annotation( "FMA:86767") AnnotationAssertion(rdfs:comment "Multi-potency demonstrated ex vivo. At the time of writing, it is unclear whether the endogenous population differentiates into multiple cell types in vivo.") AnnotationAssertion(rdfs:label "multi-potent skeletal muscle stem cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) # Class: (stratified epithelial stem cell) @@ -32775,25 +16747,6 @@ SubClassOf(Annotation( AnnotationAssertion(rdfs:label "stratified epithelial stem cell") SubClassOf( ) -# Class: (sphincter associated smooth muscle cell) - -AnnotationAssertion(Annotation( "GOC:cjm") "A smooth muscle cell that is part of a sphincter. A sphincter is a typically circular muscle that normally maintains constriction of a natural body passage or orifice and which relaxes as required by normal physiological functioning.") -AnnotationAssertion(rdfs:label "sphincter associated smooth muscle cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (vascular associated smooth muscle cell) - -AnnotationAssertion(Annotation( "GOC:dsd") Annotation( "GOC:tfm") "A smooth muscle cell associated with the vasculature.") -AnnotationAssertion( ) -AnnotationAssertion( "VSMC") -AnnotationAssertion( "vascular smooth muscle cell") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "vascular associated smooth muscle cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) - # Class: (epidermal cell) AnnotationAssertion(Annotation( "Flybase:dsj") Annotation( "MA:ma") "An epithelial cell of the integument (the outer layer of an organism).") @@ -32804,9 +16757,7 @@ AnnotationAssertion( "FMA:62411") "cell of epidermis") AnnotationAssertion(Annotation( "FMA:62411") "epithelial cell of skin") AnnotationAssertion(rdfs:label "epidermal cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -SubClassOf( ) # Class: (animal zygote) @@ -32816,15 +16767,9 @@ AnnotationAssertion( "EHDAA2:0004546") AnnotationAssertion( "FMA:72395") AnnotationAssertion(rdfs:label "animal zygote") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) -# Class: (tracheoblast) - -AnnotationAssertion(rdfs:label "tracheoblast") -SubClassOf( ) - # Class: (prohemocyte (sensu Nematoda and Protostomia)) AnnotationAssertion(Annotation( "doi:10.1016/B978-012369493-5.50008-0") "A precursor of mature hemocytes.") @@ -32833,11 +16778,6 @@ AnnotationAssertion( "prohemocyte (sensu Nematoda and Protostomia)") SubClassOf( ) -# Class: (attachment cell) - -AnnotationAssertion(rdfs:label "attachment cell") -SubClassOf( ) - # Class: (hemocyte (sensu Arthropoda)) AnnotationAssertion(Annotation( "doi:10.1016/B978-012369493-5.50008-0") "A blood cell of the circulatory system of arthropods.") @@ -32847,16 +16787,6 @@ SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (tendon cell) - -AnnotationAssertion(Annotation( "GOC:NV") Annotation( "GOC:tfm") Annotation( "PMID:957445") "An elongated fibrocyte that is part of a tendon. The cytoplasm is stretched between the collagen fibres of the tendon. They have a central cell nucleus with a prominent nucleolus. Tendon cells have a well-developed rough endoplasmic reticulum and they are responsible for synthesis and turnover of tendon fibres and ground substance.") -AnnotationAssertion( "muscle attachment cell") -AnnotationAssertion( "tenocyte") -AnnotationAssertion(rdfs:label "tendon cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) - # Class: (blood cell (sensu Nematoda and Protostomia)) AnnotationAssertion( ) @@ -32869,12 +16799,6 @@ AnnotationAssertion(Annotation( "electrically responsive cell") SubClassOf( ) -# Class: (ganglion interneuron) - -AnnotationAssertion(rdfs:label "ganglion interneuron") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - # Class: (CNS interneuron) AnnotationAssertion(Annotation( "doi:10.1016/B978-0-12-817424-1.00001-X") "An interneuron that has its cell body in a central nervous system.") @@ -32882,7 +16806,6 @@ AnnotationAssertion( ) AnnotationAssertion(rdfs:comment "Interneurons are commonly described as being only found in the central nervous system. However, in CL we define 'interneuron' more broadly as any neuron that is neither a motor neuron nor a sensory neuron, regardless of its location, so we need this term to refer strictly to interneurons of the central nervous system.") AnnotationAssertion(rdfs:label "CNS interneuron") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (electrically signaling cell) @@ -32895,22 +16818,13 @@ SubClassOf( "BTO:0001277") AnnotationAssertion( "CALOHA:TS-0949") AnnotationAssertion(rdfs:label "male gamete") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) SubClassOf(Annotation( "true") ) -SubClassOf( ) # Class: (polyploid cell) -AnnotationAssertion(Annotation( "FB:ma") "A cell whose nucleus, or nuclei, each contain more than two haploid genomes.") +AnnotationAssertion(Annotation( "https://bio.libretexts.org/Bookshelves/Introductory_and_General_Biology/Biology_(Kimball)/07%3A_Cell_Division/7.04%3A_Polyploidy"^^xsd:anyURI) Annotation( "FB:ma") Annotation( "PMID:32646579") "A cell that contains more than two haploid sets of chromosomes.") AnnotationAssertion(rdfs:label "polyploid cell") -SubClassOf( ) - -# Class: (haploid cell) - -AnnotationAssertion(Annotation( "FB:ma") Annotation( "GOC:tfm") "A cell whose nucleus contains a single haploid genome.") -AnnotationAssertion(rdfs:label "haploid cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (endopolyploid cell) @@ -32939,13 +16853,11 @@ SubClassOf( "GOC:tfm") "A peptide hormone secreting cell pituitary that produces luteinizing hormone.") AnnotationAssertion(rdfs:label "luteinizing hormone secreting cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (prolactin secreting cell) AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "SANBI:mhl") "A peptide hormone cell that secretes prolactin.") AnnotationAssertion(rdfs:label "prolactin secreting cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (melanocyte stimulating hormone secreting cell) @@ -32954,28 +16866,10 @@ AnnotationAssertion( "melanotrope") AnnotationAssertion( "melanotroph") AnnotationAssertion(rdfs:label "melanocyte stimulating hormone secreting cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (follicle stem cell (sensu Arthropoda)) - -AnnotationAssertion(Annotation( "doi:10.1016/B978-012369493-5.50005-5") Annotation( "doi:10.1038/s41467-020-19361-0") Annotation( "doi:10.1242/dev.121.11.3797") "A stem cell that gives rise to the follicle cells that surround the oocyte in female arthropods.") -AnnotationAssertion(Annotation( "doi:10.1016/j.devcel.2005.08.012") "somatic stem cell") -AnnotationAssertion( "FBbt:00004903") -AnnotationAssertion(rdfs:label "follicle stem cell (sensu Arthropoda)") -SubClassOf( ) -SubClassOf(Annotation( "https://github.com/obophenotype/cell-ontology/issues/1943") ObjectSomeValuesFrom( )) # Class: (calcitonin secreting cell) AnnotationAssertion(rdfs:label "calcitonin secreting cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (obliquely striated muscle cell) - -AnnotationAssertion(Annotation( "GOC:DOS") Annotation( "PMID:8720463") "A muscle cell in which the fibers are organised into sarcomeres but in which adjacent myofibrils are offset from each other, producing an oblique banding pattern.") -AnnotationAssertion(rdfs:comment "Examples include the somatic muscles of nemotodes and cephalopods.") -AnnotationAssertion(rdfs:label "obliquely striated muscle cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) # Class: (chief cell of parathyroid gland) @@ -33002,7 +16896,6 @@ AnnotationAssertion(Annotation( "CALOHA:TS-1119") AnnotationAssertion( "FMA:83434") AnnotationAssertion( "white adipose cell") -AnnotationAssertion( "white fat cell") AnnotationAssertion( "white adipocyte") AnnotationAssertion(rdfs:label "white fat cell") SubClassOf( ) @@ -33034,7 +16927,6 @@ AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "dendritic cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) DisjointClasses( ) @@ -33050,38 +16942,14 @@ AnnotationAssertion( ) AnnotationAssertion(rdfs:comment "Originally described in the dendritic cell ontology (DC_CL:0000021 )(PMID:19243617). These cells are also CD1a-high, CD14-negative, CD207-positive (langerin), CD324-positive (E-cadherin), and DCIR-positive. They reside in the epidermis.") AnnotationAssertion(rdfs:label "Langerhans cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (epinephrine secreting cell) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:12438093") "A cell capable of producing epinephrine. Epiniphrine is synthesized from norepiniphrine by the actions of the phenylethanolamine N-methyltransferase enzyme, which is expressed in the adrenal glands, androgenic neurons, and in other cell types.") -AnnotationAssertion(Annotation( "GO:0048242") "adrenaline secreting cell") -AnnotationAssertion( "epinephrin secreting cell") -AnnotationAssertion(rdfs:label "epinephrine secreting cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (mineralocorticoid secreting cell) - -AnnotationAssertion(rdfs:label "mineralocorticoid secreting cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (biogenic amine secreting cell) AnnotationAssertion(rdfs:label "biogenic amine secreting cell") SubClassOf( ) -# Class: (serotonin secreting cell) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:19630576") "A cell type that secretes 5-Hydroxytryptamine (serotonin).") -AnnotationAssertion( "5-HT secreting cell") -AnnotationAssertion( "5-Hydroxytryptamine secreting cell") -AnnotationAssertion(rdfs:label "serotonin secreting cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - # Class: (noradrenergic cell) AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "ISBN:068340007X") "A cell capable of producting norepiniphrine. Norepiniphrine is a catecholamine with multiple roles including as a hormone and a neurotransmitter. In addition, epiniphrine is synthesized from norepiniphrine by the actions of the phenylethanolamine N-methyltransferase enzyme.") @@ -33089,13 +16957,11 @@ AnnotationAssertion( "norepinephrin secreting cell") AnnotationAssertion( "norepinephrine secreting cell") AnnotationAssertion(rdfs:label "noradrenergic cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) # Class: (glucocorticoid secreting cell) AnnotationAssertion(rdfs:label "glucocorticoid secreting cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (adrenocorticotropic hormone secreting cell) @@ -33106,39 +16972,12 @@ AnnotationAssertion( "corticotropin hormone secreting cell") AnnotationAssertion(Annotation( "GO:0051458") "corticotropin secreting cell") AnnotationAssertion(rdfs:label "adrenocorticotropic hormone secreting cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (defensive cell) AnnotationAssertion(Annotation( "JB:jb") "A cell whose primary function is to protect the organism.") AnnotationAssertion(rdfs:label "defensive cell") -SubClassOf( ) - -# Class: (follicle cell of egg chamber) - -AnnotationAssertion( "A somatic epithelial cell of the insect egg chamber.") -AnnotationAssertion( "follicle cell") -AnnotationAssertion( "ovarian follicle cell") -AnnotationAssertion( "FBbt:00004904") -AnnotationAssertion(rdfs:label "follicle cell of egg chamber") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf(Annotation( ) ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (juvenile hormone secreting cell) - -AnnotationAssertion(Annotation( "GO:tfm") "An endocrine cell that secretes juvenile hormone.") -AnnotationAssertion( "FBbt:00058020") -AnnotationAssertion(rdfs:label "juvenile hormone secreting cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (visible light photoreceptor cell) - -AnnotationAssertion(Annotation( "GOC:tfm") "A photoreceptor cell that detects visible light.") -AnnotationAssertion(rdfs:label "visible light photoreceptor cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) +SubClassOf( ) # Class: (inhibitory interneuron) @@ -33164,7 +17003,6 @@ SubClassOf( ObjectSomeValuesFrom( "An epithelial somatic cell associated with a maturing oocyte.") AnnotationAssertion(rdfs:label "follicular epithelial cell") SubClassOf( ) -SubClassOf( ) # Class: (granulosa cell) @@ -33241,7 +17079,6 @@ SubClassOf( "GOC:tfm") Annotation( "ISBN:0198529171") "A paracrine cell is a secretory cell that secretes an agonist into intercellular spaces in which it diffuses to a target cell other than that which produced it.") AnnotationAssertion(rdfs:label "paracrine cell") SubClassOf( ) -SubClassOf( ) # Class: (cardiac muscle myoblast) @@ -33250,7 +17087,6 @@ AnnotationAssertion( "cardiac muscle progenitor cell") AnnotationAssertion( "cardiomyocyte progenitor cell") AnnotationAssertion(rdfs:label "cardiac muscle myoblast") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) # Class: (smooth muscle myoblast) @@ -33260,9 +17096,6 @@ AnnotationAssertion( "MESH:D032390") "myoblast, smooth muscle") AnnotationAssertion( "satellite cell") AnnotationAssertion(rdfs:label "smooth muscle myoblast") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) # Class: (skeletal muscle myoblast) @@ -33270,18 +17103,8 @@ AnnotationAssertion(Annotation( "FMA:84799") AnnotationAssertion( "skeletal myoblast") AnnotationAssertion(rdfs:label "skeletal muscle myoblast") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (fungal cell) - -AnnotationAssertion(rdfs:label "fungal cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -DisjointClasses( ) - # Class: (syncytiotrophoblast cell) AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "ISBN:0323052908") "A cell from the outer syncytial layer of the trophoblast of an early mammalian embryo, directly associated with the maternal blood supply. It secretes hCG in order to maintain progesterone secretion and sustain a pregnancy.") @@ -33294,7 +17117,6 @@ AnnotationAssertion( ) AnnotationAssertion(rdfs:label "syncytiotrophoblast cell") AnnotationAssertion(rdfs:seeAlso "https://github.com/obophenotype/cell-ontology/issues/2100") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ObjectSomeValuesFrom( )) # Class: (afferent neuron) @@ -33335,18 +17157,6 @@ SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (melanoblast) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "SANBI:mhl") "A cell that originates from the neural crest and differentiates into a pigment cell.") -AnnotationAssertion( "BTO:0003217") -AnnotationAssertion( "FMA:83377") -AnnotationAssertion(rdfs:comment "Derived from UBERON:0002342 neural crest.") -AnnotationAssertion(rdfs:label "melanoblast") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (lymphocyte) AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0683073696") Annotation( "ISBN:0781735149") "A lymphocyte is a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin.") @@ -33359,7 +17169,6 @@ AnnotationAssertion( ) AnnotationAssertion(rdfs:comment "Editors note: consider adding taxon constraint to vertebrata (PMID:18025161)") AnnotationAssertion(rdfs:label "lymphocyte") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) SubClassOf( ObjectSomeValuesFrom( )) DisjointClasses( ) @@ -33372,21 +17181,9 @@ AnnotationAssertion(Annotation( "pronormoblast") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "proerythroblast") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (animal cell) - -AnnotationAssertion( "A native cell that is part of some Metazoa.") -AnnotationAssertion( "metazoan cell") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "animal cell") -AnnotationAssertion( "https://www.swissbiopics.org/api/image/Animal_cells.svg"^^xsd:anyURI) -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (basophilic erythroblast) AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "ISBN:0721601464") "A nucleated immature erythrocyte, having cytoplasm generally similar to that of the earlier proerythroblast but sometimes even more basophilic, and usually regular in outline. The nucleus is still relatively large, but the chromatin strands are thicker and more deeply staining, giving a coarser appearance; the nucleoli have disappeared. This cell is CD71-positive and lacks hematopoeitic lineage markers.") @@ -33396,7 +17193,6 @@ AnnotationAssertion(Annotation( "ISBN:0721601464") "early normoblast") AnnotationAssertion(Annotation( "ISBN:0721601464") "prorubricyte") AnnotationAssertion(rdfs:label "basophilic erythroblast") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) SubClassOf( ObjectSomeValuesFrom( )) @@ -33411,7 +17207,6 @@ AnnotationAssertion(Annotation( "ISBN:0721601464") "polychromatophilic normoblast") AnnotationAssertion(Annotation( "ISBN:0721601464") "rubricyte") AnnotationAssertion(rdfs:label "polychromatophilic erythroblast") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) SubClassOf( ObjectSomeValuesFrom( )) @@ -33425,7 +17220,6 @@ AnnotationAssertion( "ISBN:0721601464") "orthochromatic normoblast") AnnotationAssertion(Annotation( "ISBN:0721601464") "pyknotic eto enrythroblast") AnnotationAssertion(rdfs:label "orthochromatic erythroblast") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) SubClassOf( ObjectSomeValuesFrom( )) @@ -33450,7 +17244,6 @@ AnnotationAssertion( ) AnnotationAssertion(rdfs:comment "Lineage negative is described here as CD2-negative, CD3-negative, CD4-negative, CD5-negative, CD8a-negative, CD14-negative, CD19-negative, CD20-negative, CD56-negative, Ly6g-negative, and Ter119-negative.") AnnotationAssertion(rdfs:label "megakaryocyte progenitor cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) SubClassOf( ObjectSomeValuesFrom( )) @@ -33492,7 +17285,6 @@ AnnotationAssertion(Annotation( ) AnnotationAssertion(rdfs:comment "Originally described in the dendritic cell ontology (DC_CL:0000042)(PMID:19243617). GMPs are reportedly CD16-positive, CD32-positive, CD34-positive, CD38-positive, CD45RA-positive, CD110-negative, CD117-positive, CD123-positive, and SCA1-negative.") AnnotationAssertion(rdfs:label "granulocyte monocyte progenitor cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) SubClassOf( ObjectSomeValuesFrom( )) @@ -33504,7 +17296,6 @@ AnnotationAssertion( "MESH:D012156") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "reticulocyte") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) SubClassOf( ObjectSomeValuesFrom( )) @@ -33517,7 +17308,6 @@ AnnotationAssertion( ) AnnotationAssertion(rdfs:comment "Morphology: Mononuclear cell, diameter 14-18 _M, fine azurophilic granules; markers: CD11b (shared with many other myeloid cells); location: Adult: bone marrow; Fetal: Liver, Yolk Sac; role or process: hematopoiesis, monocyte development; lineage: hematopoietic, myeloid.") AnnotationAssertion(rdfs:label "promonocyte") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) SubClassOf( ObjectSomeValuesFrom( )) @@ -33529,7 +17319,7 @@ AnnotationAssertion( "FMA:67766") AnnotationAssertion( "amacrine neuron") AnnotationAssertion(Annotation( "doi:10.1038/s41598-020-66092-9") Annotation( ) "AC") -AnnotationAssertion(Annotation( "doi:10.1038/s41598-020-66092-9") Annotation( ) Annotation( ) "ACs") +AnnotationAssertion(Annotation( "doi:10.1038/s41598-020-66092-9") Annotation( ) Annotation( ) "ACs") AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "amacrine cell") @@ -33538,16 +17328,6 @@ SubClassOf( ObjectSomeValuesFrom( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (nucleate erythrocyte) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOc:tfm") "An erythrocyte having a nucleus.") -AnnotationAssertion( "RBC") -AnnotationAssertion( "red blood cell") -AnnotationAssertion(rdfs:label "nucleate erythrocyte") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (angioblastic mesenchymal cell) AnnotationAssertion(Annotation( "GOC:dsd") Annotation( "GOC:tfm") Annotation( "PMID:12768659") "A mesenchymal stem cell capable of developing into blood vessel endothelium.") @@ -33557,7 +17337,6 @@ AnnotationAssertion( ) AnnotationAssertion(rdfs:comment "These cells are reportedly CD31-positive, CD34-positive, CD144-positive, CD309-positive, and TAL1-positive.") AnnotationAssertion(rdfs:label "angioblastic mesenchymal cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) SubClassOf( ObjectSomeValuesFrom( )) @@ -33571,13 +17350,6 @@ AnnotationAssertion( "amine precursor uptake and decarboxylation cell") SubClassOf( ) -# Class: (cardiac mesenchymal cell) - -AnnotationAssertion(Annotation( "PMID:18816864") "A mesenchymal cell found in the developing heart and that develops into some part of the heart. These cells derive from intra- and extra-cardiac sources, including the endocardium, epicardium, neural crest, and second heart field.") -AnnotationAssertion(rdfs:label "cardiac mesenchymal cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - # Class: (parafollicular cell) AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "ISBN:0517223651") "A neuroepithelial cells that occurs singly or in small groups, close to the outer follicular borders but within the follicular basement membrane of the thyroid. Expresses a form of the neural cell adhesion molecule (N-CAM) on their surface. Secretes calcitonin, 5-hydroxytryptamine and dopamine.") @@ -33589,7 +17361,6 @@ AnnotationAssertion(Annotation( "FMA:68653") "parafollicular cell of thyroid gland") AnnotationAssertion(Annotation( "FMA:68653") "thyroid parafollicular cell") AnnotationAssertion(rdfs:label "parafollicular cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) SubClassOf(Annotation( "true") ) SubClassOf( ObjectSomeValuesFrom( )) @@ -33608,21 +17379,6 @@ AnnotationAssertion(rdfs:label "reti SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (corneal epithelial cell) - -AnnotationAssertion(Annotation( "GOC:tfm") "An epithelial cell of the cornea.") -AnnotationAssertion( ) -AnnotationAssertion( "BTO:0004298") -AnnotationAssertion( "CALOHA:TS-0173") -AnnotationAssertion( "FMA:70551") -AnnotationAssertion(Annotation( "FMA:70551") "epithelial cell of cornea") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "corneal epithelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - # Class: (monocyte) AnnotationAssertion(Annotation( "GO_REF:0000031") Annotation( "MESH:D009000") "Myeloid mononuclear recirculating leukocyte that can act as a precursor of tissue macrophages, osteoclasts and some populations of tissue dendritic cells.") @@ -33635,7 +17391,6 @@ AnnotationAssertion( ) AnnotationAssertion(rdfs:comment "Morphology: Mononuclear cell, diameter, 14 to 20 _M, N/C ratio 2:1-1:1. Nucleus may appear in variety of shapes: round, kidney, lobulated, or convoluted. Fine azurophilic granules present; markers: CD11b (shared with other myeloid cells), human: CD14, mouse: F4/80-mid,GR1-low; location: Blood, but can be recruited into tissues; role or process: immune & tissue remodelling; lineage: hematopoietic, myeloid.") AnnotationAssertion(rdfs:label "monocyte") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) SubClassOf( ObjectSomeValuesFrom( )) @@ -33650,30 +17405,10 @@ AnnotationAssertion(rdfs:label "germ SubClassOf(Annotation( "true") ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (odontoclast) - -AnnotationAssertion(Annotation( "GOC:add") "A specialized osteoclast associated with the absorption and removal of cementum.") -AnnotationAssertion( "BTO:0002516") -AnnotationAssertion( "FMA:83027") -AnnotationAssertion(rdfs:label "odontoclast") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - # Class: (androgen secreting cell) AnnotationAssertion(Annotation( "GOC:tfm") "A steroid hormone secreting cell that secretes androgen.") AnnotationAssertion(rdfs:label "androgen secreting cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (enucleate erythrocyte) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:tfm") "An erythrocyte lacking a nucleus.") -AnnotationAssertion( "red blood cell") -AnnotationAssertion(Annotation( ) "RBC") -AnnotationAssertion(rdfs:label "enucleate erythrocyte") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) # Class: (pyramidal neuron) @@ -33684,10 +17419,8 @@ AnnotationAssertion( "NIFSTD:sao862606388") AnnotationAssertion( "projection neuron") AnnotationAssertion( "pyramidal cell") -AnnotationAssertion( "pyramidal neuron") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "pyramidal neuron") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (retinal rod cell) @@ -33702,26 +17435,6 @@ AnnotationAssertion(rdfs:label "reti SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (vestibular hair cell) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "MESH:D018069") "A mechanoreceptor located in the acoustic maculae and the semicircular canals that mediates the sense of balance, movement, and head position. The vestibular hair cells are connected to accessory structures in such a way that movements of the head displace their stereocilia. This influences the membrane potential of the cells which relay information about movements via the vestibular part of the vestibulocochlear nerve to the brain stem.") -AnnotationAssertion( "FMA:62351") -AnnotationAssertion( "vestibular receptor cell") -AnnotationAssertion(rdfs:label "vestibular hair cell") -SubClassOf( ) - -# Class: (GABAergic neuron) - -AnnotationAssertion(Annotation( "GOC:tfm") "A neuron that uses GABA as a vesicular neurotransmitter") -AnnotationAssertion( "FBbt:00007228") -AnnotationAssertion( "FMA:84788") -AnnotationAssertion( "MESH:D059330") -AnnotationAssertion( "WBbt:0005190") -AnnotationAssertion( "GABA-ergic neuron") -AnnotationAssertion(rdfs:label "GABAergic neuron") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - # Class: (acinar cell) AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "http://www.copewithcytokines.de") "A secretory cell that is grouped together with other cells of the same type to form grape shaped clusters known as acini (singular acinus).") @@ -33740,7 +17453,6 @@ AnnotationAssertion(Annotation( "doi:10.1038/s41598-018-27692-8") "olfactory bulb granule cell") AnnotationAssertion(Annotation( "doi:10.1038/s41598-018-27692-8") rdfs:comment "Granule cells are the most abundant neuronal population in the olfactory bulb and are continuously renewed throughout life.") AnnotationAssertion(rdfs:label "olfactory granule cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) @@ -33748,40 +17460,13 @@ SubClassOf( ObjectSomeValuesFrom( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (transporting cell) - -AnnotationAssertion(Annotation( "TAIR:sr") "A cell involved in transporting nutrients, minerals, water, gases and other chemicals between cells for a variety of purposes including conveying nutrition to other tissues, removing waste products from the tissues, conveying gases for respiration, distributing heat and repelling invasion of foreign substances.") -AnnotationAssertion(rdfs:label "transporting cell") -SubClassOf( ) - # Class: (supporting cell) AnnotationAssertion(Annotation( "FB:ma") Annotation( "GOC:tfm") "A cell whose primary function is to support other cell types.") AnnotationAssertion( "BTO:0002315") AnnotationAssertion( "supportive cell") AnnotationAssertion(rdfs:label "supporting cell") -SubClassOf( ) - -# Class: (hepatic stellate cell) - -AnnotationAssertion(Annotation( "GOC:dsd") Annotation( "MESH:D055166") Annotation( "PMID:12808230") Annotation( "PMID:17239632") Annotation( "PMID:18222966") Annotation( "PMID:9302568") Annotation( "http://en.wikipedia.org/wiki/Hepatic_stellate_cell") "A cell that is found in the perisinusoidal space of the liver that is capable of multiple roles including storage of retinol, presentation of antigen to T cells (including CD1d-restricted NKT cells), and upon activation, production of extracellular matrix components that can contribute to liver fibrosis. This activated state has a myofibroblast-like phenotype, though it's not clear in the literature if this is terminally differentiated. This cell type comprises approximately 8-15% of total cells in the liver.") -AnnotationAssertion( ) -AnnotationAssertion( "BTO:0002741") -AnnotationAssertion( "CALOHA:TS-0452") -AnnotationAssertion( "FMA:67763") -AnnotationAssertion( "Ito cell") -AnnotationAssertion( "hepatic perisinusoidal cell") -AnnotationAssertion( "perisinusoidal cell") -AnnotationAssertion( "fat-storing cell") -AnnotationAssertion( "lipocyte") -AnnotationAssertion(Annotation( "PMID:12808230") "vitamin A-storing cells") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "Hepatic stellate cells are CD271-positive, desmin-positive, DDR-2-positive, GFAP-positive, synamin-positive, synaptophysin-positive, vimentin-positive, They are capable of producing angiotensin II, fibronectin, laminin, MMP-1, MMP-2, MMP-3, MMP-9, MMP-11, TGF-beta1, TIMP-1, TIMP-2, type I collagen, type III collagen, type IV collagen, and type VI collagen.") -AnnotationAssertion(rdfs:label "hepatic stellate cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf(Annotation( "true") ) +SubClassOf( ) # Class: (Mueller cell) @@ -33803,7 +17488,6 @@ SubClassOf( ObjectSomeValuesFrom( "GOC:tfm") Annotation( "ISBN:0618947256") "A cell that stains readily in the anterior pituitary gland.") AnnotationAssertion( "FMA:83089") AnnotationAssertion(rdfs:label "chromophil cell of anterior pituitary gland") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) @@ -33830,7 +17514,6 @@ AnnotationAssertion(Annotation( "PMID:18287078") Annotation( "PMID:31620083") Annotation( "PMID:34734454") Annotation( "doi:10.23937/2572-407X.1510006") rdfs:comment "Folliculostellate cells are a heterogeneous group of cells rather than a single cell type, with different morphology and gene expression profiles. Due to this heterogeneity, it is unclear if different properties that have been attributed to folliculostellate cells (pluripotent, proliferative, phagocytic) are common in all folliculostellate cells or limited to particular subsets.") AnnotationAssertion(rdfs:label "folliculostellate cell") SubClassOf( ) -SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) @@ -33854,7 +17537,6 @@ AnnotationAssertion( "renin secreting cell") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "kidney granular cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) @@ -33908,33 +17590,8 @@ AnnotationAssertion( ) AnnotationAssertion(rdfs:label "podocyte") AnnotationAssertion(rdfs:seeAlso "https://github.com/obophenotype/cell-ontology/issues/1460") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (primary oocyte) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "ISBN:0721662544") "A primary oocyte is an oocyte that has not completed female meosis I.") -AnnotationAssertion( ) -AnnotationAssertion( "BTO:0000512") -AnnotationAssertion( "FMA:18645") -AnnotationAssertion( "primary oogonium") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "primary oocyte") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (secondary oocyte) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "ISBN:0721662544") "A secondary oocyte is an oocyte that has not completed meiosis II.") -AnnotationAssertion( "BTO:0003094") -AnnotationAssertion( "FMA:18646") -AnnotationAssertion( "primary oogonium") -AnnotationAssertion(rdfs:label "secondary oocyte") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (primary spermatocyte) AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "ISBN:0721662544") "A diploid cell that has derived from a spermatogonium and can subsequently begin meiosis and divide into two haploid secondary spermatocytes.") @@ -33942,9 +17599,6 @@ AnnotationAssertion( "CALOHA:TS-2194") AnnotationAssertion( "FMA:72292") AnnotationAssertion(rdfs:label "primary spermatocyte") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) # Class: (secondary spermatocyte) @@ -33954,18 +17608,8 @@ AnnotationAssertion( "FBbt:00004941") AnnotationAssertion( "FMA:72293") AnnotationAssertion(rdfs:label "secondary spermatocyte") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (fenestrated cell) - -AnnotationAssertion( "window cell") -AnnotationAssertion(rdfs:label "fenestrated cell") -SubClassOf( ) -SubClassOf( ) - # Class: (collagen secreting cell) AnnotationAssertion(Annotation( "GOC:tfm") "An extracellular matrix secreting cell that secretes collagen.") @@ -33992,18 +17636,6 @@ SubClassOf( ) SubClassOf( ) -# Class: (primordial germ cell) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:1381289") "A primordial germ cell is a diploid germ cell precursors that transiently exist in the embryo before they enter into close association with the somatic cells of the gonad and become irreversibly committed as germ cells.") -AnnotationAssertion( "FMA:70567") -AnnotationAssertion( "gonocyte") -AnnotationAssertion( "primitive germ cell") -AnnotationAssertion(rdfs:label "primordial germ cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) -SubClassOf( ) - # Class: (female gamete) AnnotationAssertion(Annotation( "GOC:tfm") "A mature sexual reproductive cell of the female germline.") @@ -34019,17 +17651,13 @@ AnnotationAssertion( "WBbt:0006829") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "glutamatergic neuron") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) # Class: (muscle precursor cell) AnnotationAssertion(Annotation( "GOC:add") "A non-terminally differentiated cell that is capable of developing into a muscle cell.") AnnotationAssertion(rdfs:label "muscle precursor cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -SubClassOf( ) -SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) # Class: (radial glial cell) @@ -34042,12 +17670,6 @@ AnnotationAssertion(rdfs:label "radi SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (stellate interneuron) - -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "stellate interneuron") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (PP cell) AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "JB:jb") Annotation( "PMID:15153415") "A cell that stores and secretes pancreatic polypeptide hormone.") @@ -34068,7 +17690,6 @@ AnnotationAssertion( "WBbt:0006746") AnnotationAssertion( "dopaminergic cell") AnnotationAssertion(rdfs:label "dopaminergic neuron") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) @@ -34079,26 +17700,6 @@ AnnotationAssertion( "sustentacular cell") SubClassOf( ) -# Class: (choroid plexus epithelial cell) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:tfm") Annotation( "JB:jb") Annotation( "PMID:9550134") "Specialized ependymal cell that produces the cerebrospinal fluid from the blood and secretes it into the lumen of the brain and spinal chord.") -AnnotationAssertion( "2023-08-04T08:48:30Z"^^xsd:dateTime) -AnnotationAssertion(Annotation( "DOI:10.1101/2022.10.12.511898") "choroid plexus cell") -AnnotationAssertion( "FMA:70549") -AnnotationAssertion( "epithelial cell of choroid plexus") -AnnotationAssertion(rdfs:label "choroid plexus epithelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (leptomeningeal cell) - -AnnotationAssertion(Annotation( "JB:jb") "Stromal cell that forms the internal covering of the vertebrate brain and produces ECM for this and the choroid plexus.") -AnnotationAssertion( "leptomemingeal cell") -AnnotationAssertion(rdfs:label "leptomeningeal cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) - # Class: (neurecto-epithelial cell) AnnotationAssertion(Annotation( "GOC:tfm") "Epithelial cells derived from neural plate and neural crest.") @@ -34107,13 +17708,11 @@ AnnotationAssertion( "FMA:70557") AnnotationAssertion(rdfs:comment "The term \"neuroepithelial cell\" is used to describe both this cell type and sensory epithelial cell (CL:0000098).") AnnotationAssertion(rdfs:label "neurecto-epithelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) # Class: (stratum granulosum cell) AnnotationAssertion(rdfs:label "stratum granulosum cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) @@ -34124,18 +17723,6 @@ AnnotationAssertion( "FMA:63368") AnnotationAssertion( "MESH:D053687") AnnotationAssertion(rdfs:label "somatic stem cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) - -# Class: (urothelial cell) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "MA:ma") Annotation( "doi:10.1038/s41385-022-00565-0") "A cell of a layer of transitional epithelium in the wall of the proximal urethra, bladder, ureter or renal pelvis, external to the lamina propria.") -AnnotationAssertion( "FMA:84127") -AnnotationAssertion( "urinary tract transitional epithelial cell") -AnnotationAssertion(rdfs:label "urothelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) # Class: (striated muscle cell) @@ -34144,7 +17731,6 @@ AnnotationAssertion( "CALOHA:TS-2157") AnnotationAssertion( "FMA:86936") AnnotationAssertion(rdfs:label "striated muscle cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf( ) DisjointClasses( ) @@ -34162,7 +17748,6 @@ AnnotationAssertion( "immune cell") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "leukocyte") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) @@ -34178,7 +17763,7 @@ AnnotationAssertion( "gangliocyte") AnnotationAssertion( "ganglion cell of retina") AnnotationAssertion(Annotation( "doi:10.1038/s41598-020-66092-9") Annotation( ) "RGC") -AnnotationAssertion(Annotation( "doi:10.1038/s41598-020-66092-9") Annotation( ) Annotation( ) "RGCs") +AnnotationAssertion(Annotation( "doi:10.1038/s41598-020-66092-9") Annotation( ) Annotation( ) "RGCs") AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "retinal ganglion cell") @@ -34192,7 +17777,7 @@ AnnotationAssertion( "BTO:0004120") AnnotationAssertion( "horizontal cell") AnnotationAssertion(Annotation( "doi:10.1038/s41598-020-66092-9") Annotation( ) "HC") -AnnotationAssertion(Annotation( "doi:10.1038/s41598-020-66092-9") Annotation( ) Annotation( ) "HCs") +AnnotationAssertion(Annotation( "doi:10.1038/s41598-020-66092-9") Annotation( ) Annotation( ) "HCs") AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "retina horizontal cell") @@ -34217,7 +17802,6 @@ AnnotationAssertion( ) AnnotationAssertion(rdfs:comment "This class encompasses the muscle cells responsible for heart* contraction in both vertebrates and arthropods. The ultrastucture of a wide range of arthropod heart cells has been examined including spiders, horseshoe crabs, crustaceans (see Sherman, 1973 and refs therein) and insects (see Lehmacher et al (2012) and refs therein). According to these refs, the cells participating in heart contraction in all cases are transversely striated. Insects hearts additionally contain ostial cells, also transversely striated muscle cells, but which do not participate in heart contraction.") AnnotationAssertion(rdfs:label "cardiac muscle cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf( ObjectSomeValuesFrom( )) # Class: (retinal bipolar neuron) @@ -34225,33 +17809,15 @@ SubClassOf( ObjectSomeValuesFrom( "PMID:14689473") "A bipolar neuron found in the retina and having connections with photoreceptors cells and neurons in the inner plexiform layer.") AnnotationAssertion( ) AnnotationAssertion(Annotation( "doi:10.1038/s41598-020-66092-9") Annotation( ) "BC") -AnnotationAssertion(Annotation( "doi:10.1038/s41598-020-66092-9") Annotation( ) Annotation( ) "BCs") -AnnotationAssertion(Annotation( "GSE137537") Annotation( ) Annotation( ) "BPs") +AnnotationAssertion(Annotation( "doi:10.1038/s41598-020-66092-9") Annotation( ) Annotation( ) "BCs") +AnnotationAssertion(Annotation( "GSE137537") Annotation( ) Annotation( ) "BPs") AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "retinal bipolar neuron") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( )))) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (cone retinal bipolar cell) - -AnnotationAssertion(Annotation( "PMID:14689473") "A bipolar neuron found in the retina and having connections with cone photoreceptor cells and neurons in the inner plexiform layer.") -AnnotationAssertion(rdfs:label "cone retinal bipolar cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (nucleated thrombocyte) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:tfm") Annotation( "PMID:16360205") "A nucleated blood cell involved in coagulation, typically seen in birds and other non-mammalian vertebrates.") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "Note that this is a non-mammalian cell type. Use platelet ; CL:0000233 for thrombocytes (platelets) in mammals.") -AnnotationAssertion(rdfs:label "nucleated thrombocyte") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (myeloid cell) AnnotationAssertion(Annotation( "GOC:add") "A cell of the monocyte, granulocyte, mast cell, megakaryocyte, or erythroid lineage.") @@ -34259,7 +17825,6 @@ AnnotationAssertion( "CALOHA:TS-0647") AnnotationAssertion( "MESH:D022423") AnnotationAssertion(rdfs:label "myeloid cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) # Class: (erythroid lineage cell) @@ -34285,7 +17850,6 @@ AnnotationAssertion( "normoblast") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "erythroblast") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) SubClassOf( ObjectSomeValuesFrom( )) @@ -34295,95 +17859,8 @@ AnnotationAssertion(Annotation( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "myeloid leukocyte") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) -# Class: (neutrophil) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:amm") Annotation( "GOC:tfm") Annotation( "ISBN:0721601464") "Any of the immature or mature forms of a granular leukocyte that in its mature form has a nucleus with three to five lobes connected by slender threads of chromatin, and cytoplasm containing fine inconspicuous granules and stainable by neutral dyes.") -AnnotationAssertion( ) -AnnotationAssertion( "PMN") -AnnotationAssertion( "poly") -AnnotationAssertion( "polymorphonuclear leucocyte") -AnnotationAssertion( "polymorphonuclear leukocyte") -AnnotationAssertion( "polymorphonuclear neutrophil") -AnnotationAssertion( "polynuclear neutrophilic leucocyte") -AnnotationAssertion( "polynuclear neutrophilic leukocyte") -AnnotationAssertion( "BTO:0000130") -AnnotationAssertion( "CALOHA:TS-0688") -AnnotationAssertion( "FMA:62860") -AnnotationAssertion( "MESH:D009504") -AnnotationAssertion( "neutrocyte") -AnnotationAssertion( "neutrophil leucocyte") -AnnotationAssertion( "neutrophil leukocyte") -AnnotationAssertion( "neutrophilic leucocyte") -AnnotationAssertion( "neutrophilic leukocyte") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "neutrophil") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (mesangial phagocyte) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:tfm") Annotation( "ISBN:0702022918") Annotation( "ISBN:3540536663") Annotation( "PMID:1600140") Annotation( "PMID:16146841") "A tissue-resident macrophage of the renal glomerular mesangium involved in the disposal and degradation of filtration residues, presentation of antigen to T cells and in tissue remodeling.") -AnnotationAssertion( "mesangial cell") -AnnotationAssertion(rdfs:label "mesangial phagocyte") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (mononuclear osteoclast) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:tfm") Annotation( "PMID:12713016") Annotation( "PMID:15055519") Annotation( "PMID:17380158") Annotation( "PMID:9415452") "A specialized mononuclear osteoclast associated with the absorption and removal of bone, precursor of multinuclear osteoclasts.") -AnnotationAssertion(rdfs:comment "Morphology: mononuclear, highly vesicular.") -AnnotationAssertion(rdfs:label "mononuclear osteoclast") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (multinuclear osteoclast) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "PMID:12713016") Annotation( "PMID:9415452") "A specialized multinuclear osteoclast associated with the absorption and removal of bone.") -AnnotationAssertion( "multinucleated osteoclast") -AnnotationAssertion(rdfs:comment "Morphology: multinucleated, highly vesicular.") -AnnotationAssertion(rdfs:label "multinuclear osteoclast") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (multinuclear odontoclast) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "PMID:9415452") "A specialized multinuclear osteoclast associated with the absorption and removal of cementum.") -AnnotationAssertion( "multinucleated odontoclast") -AnnotationAssertion(rdfs:comment "Morphology: multinucleated, highly vesicular; location: roots of deciduous (milk) teeth.") -AnnotationAssertion(rdfs:label "multinuclear odontoclast") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (mononuclear odontoclast) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "PMID:9415452") "A specialized mononuclear osteoclast associated with the absorption and removal of cementum.") -AnnotationAssertion(rdfs:comment "Morphology: Mononuclear, highly vesicular; location: roots of deciduous (milk) teeth.") -AnnotationAssertion(rdfs:label "mononuclear odontoclast") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) - -# Class: (myeloid dendritic cell) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "PMID:10449155") Annotation( "PMID:17332250") Annotation( "PMID:9521319") "A dendritic cell of the myeloid lineage.") -AnnotationAssertion( ) -AnnotationAssertion( "interdigitating cell") -AnnotationAssertion( "veiled cell") -AnnotationAssertion( "BTO:0004721") -AnnotationAssertion( "CD11c+CD123- DC") -AnnotationAssertion( "mDC") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "These cells are CD1a-negative, CD1b-positive, CD11a-positive, CD11c-positive, CD13-positive, CD14-negative, CD20-negative, CD21-negative, CD33-positive, CD40-negative, CD50-positive, CD54-positive, CD58-positive, CD68-negative, CD80-negative, CD83-negative, CD85j-positive, CD86-positive, CD89-negative, CD95-positive, CD120a-negative, CD120b-positive, CD123-negative, CD178-negative, CD206-negative, CD207-negative, CD209-negative, and TNF-alpha-negative. Upon TLR stimulation, they are capable of producing high levels of TNF-alpha, IL-6, CXCL8 (IL-8).") -AnnotationAssertion(rdfs:label "myeloid dendritic cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - # Class: (mature B cell) AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:dsd") Annotation( "ISBN:0781735149") "A B cell that is mature, having left the bone marrow. Initially, these cells are IgM-positive and IgD-positive, and they can be activated by antigen.") @@ -34392,47 +17869,12 @@ AnnotationAssertion( "mature B-lymphocyte") AnnotationAssertion(rdfs:comment "Mature B cells are also reportedly CD10-negative, CD19-positive, CD22-positive, CD34-negative, CD48-positive, CD79a-positive, CD84-positive, CD127-negative, CD352-positive, RAG-negative, TdT-negative, Vpre-B-negative, and pre-BCR-negative. Transcription factors expressed: Pax5-positive.") AnnotationAssertion(rdfs:label "mature B cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) SubClassOf( ObjectSomeValuesFrom( )) DisjointClasses( ) DisjointClasses( ) DisjointClasses( ) -# Class: (plasma cell) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:dsd") Annotation( "GO_REF:0000031") Annotation( "ISBN:0721601464") Annotation( "ISBN:0781735149") Annotation( "PMID:19447676") Annotation( "PMID:20081059") Annotation( "PMID:20839338") Annotation( "PMID:20951740") Annotation( "http://en.wikipedia.org/wiki/Plasma_cell") "A terminally differentiated, post-mitotic, antibody secreting cell of the B cell lineage with the phenotype CD138-positive, surface immunonoglobulin-negative, and MHC Class II-negative. Plasma cells are oval or round with extensive rough endoplasmic reticulum, a well-developed Golgi apparatus, and a round nucleus having a characteristic cartwheel heterochromatin pattern and are devoted to producing large amounts of immunoglobulin.") -AnnotationAssertion( ) -AnnotationAssertion( "BTO:0000392") -AnnotationAssertion( "FMA:70574") -AnnotationAssertion( "MESH:D010950") -AnnotationAssertion( "plasma B cell") -AnnotationAssertion( "plasma B-cell") -AnnotationAssertion( "plasmacyte") -AnnotationAssertion( "plasmocyte") -AnnotationAssertion( "effector B cell") -AnnotationAssertion( "effector B-cell") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "Plasma cells develop in the spleen and migrate to the bone marrow. Plasma cells are also reportedly CD5-negative, CD10-negative, CD19-positive, CD20-negative, CD21-negative, CD22-negative, CD23-negative, CD24-negative, CD25-negative, CD27-positive, CD34-negative, CD38-positive, CD40-positive, CD43-positive, CD45-positive, CD48-positive, CD53-low, CD80-negative, CD81-positive, CD86-positive, CD95-positive, CD196-negative, CD229-positive, CD270-positive, CD352-positive, CD361-positive, and IgD-negative. Transcription factors: BLIMP1-positive, IRF4-positive, PAX5-negative, SpiB-negative, Ets1-negative, and XBP1-positive.") -AnnotationAssertion(rdfs:label "plasma cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (memory B cell) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:dsd") Annotation( "GOC:rhs") Annotation( "GO_REF:0000031") Annotation( "ISBN:0781735149") Annotation( "PMID:20081059") Annotation( "PMID:20839338") Annotation( "http://en.wikipedia.org/wiki/Memory_B_cell") "A memory B cell is a mature B cell that is long-lived, readily activated upon re-encounter of its antigenic determinant, and has been selected for expression of higher affinity immunoglobulin. This cell type has the phenotype CD19-positive, CD20-positive, MHC Class II-positive, and CD138-negative.") -AnnotationAssertion( ) -AnnotationAssertion( "memory B lymphocyte") -AnnotationAssertion( "memory B-cell") -AnnotationAssertion( "memory B-lymphocyte") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "Memory B-cells are also reportedly CD5-negative, CD10-negative, CD21-positive, CD22-positive, CD23-negative, CD24-positive, CD25-positive, CD27-positive, CD34-negative, CD38-negative, CD40-positive, CD43-negative, CD44-positive, CD45-positive, CD53-positive, CD80-negative, CD81-negative, CD86-positive, and CD196/CCR6-positive.") -AnnotationAssertion(rdfs:label "memory B cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - # Class: (naive B cell) AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:dsd") Annotation( "GOC:rhs") Annotation( "GO_REF:0000031") Annotation( "ISBN:0781765196") Annotation( "PMID:19447676") Annotation( "PMID:20081059") Annotation( "PMID:20839338") Annotation( "PMID:20933013") Annotation( "PMID:22343568") "A naive B cell is a mature B cell that has the phenotype surface IgD-positive, surface IgM-positive, CD20-positive, CD27-negative and that has not yet been activated by antigen in the periphery.") @@ -34443,7 +17885,6 @@ AnnotationAssertion( ) AnnotationAssertion(rdfs:comment "This cell type is compatible with the HIPC Lyoplate markers for 'naive B cell'. Per DSD: Naive B cells are also reportedly CD10-negative, CD19-positive, CD20-positive, CD21-positive, CD22-positive, CD25-negative, CD27-negative, CD34-negative, CD40-positive, CD43-negative, CD45-positive, CD48-positive, CD53-positive, CD80-negative, CD81-positive, CD84-positive, CD86-negative, CD95-negative, CD138-negative, CD150-positive, CD184/CXCR4-positive, CD185/CXCR5-positive, CD196/CCR6-positive, CD200-positive, CD229-positive, CD243-positive, CD289-positive, CD290-positive, CD352-positive, MHCII/HLA-DR-positive, cadherin 9-positive, and sIgH-positive, Transcription factors: Pax5-positive, ETS1-positive, FOXO1A-positive, KLF4-positive, KLF9-positive, MiTF-positive, OBF1-positive, PLZF-positive, and SpiB-positive.") AnnotationAssertion(rdfs:label "naive B cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) SubClassOf( ObjectSomeValuesFrom( )) @@ -34459,7 +17900,6 @@ AnnotationAssertion( ) AnnotationAssertion(rdfs:comment "Immature B cells are also reportedly CD5-positive, CD10-positive, CD19-positive, CD20-positive, CD21-positive, CD22-positive, CD24-positive, CD25-negative, CD27-negative, CD34-negative, CD38-positive, CD40-positive, CD43-negative, CD45-positive, CD48-positive, CD53-positive, CD79a-positive, CD80-negative, CD81-positive, CD86-negative, CD95-negative, CD127-negative, CD138-negative, CD185-positive, CD196-positive, MHCII/HLA-DR-positive, RAG-positive, TdT-negative, Vpre-B-negative, and preBCR-negative. Transcription factors expressed: Pax5-positive.") AnnotationAssertion(rdfs:label "immature B cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) @@ -34472,7 +17912,6 @@ AnnotationAssertion( "pre-B cell") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "precursor B cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) DisjointClasses( ) @@ -34490,27 +17929,9 @@ AnnotationAssertion( ) AnnotationAssertion(rdfs:comment "This cell type is compatible with the HIPC Lyoplate markers for 'transitional B cell'.") AnnotationAssertion(rdfs:label "transitional stage B cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (B-2 B cell) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:dsd") Annotation( "GOC:tfm") Annotation( "ISBN:0781735149") Annotation( "PMID:11861604") Annotation( "PMID:20933013") "A conventional B cell subject to antigenic stimulation and dependent on T cell help and with a distinct surface marker expression pattern from B-1 B cells. These cells are CD43-negative.") -AnnotationAssertion( "B-2 B lymphocyte") -AnnotationAssertion( "B-2 B-cell") -AnnotationAssertion( "B-2 B-lymphocyte") -AnnotationAssertion( "B2 B cell") -AnnotationAssertion( "B2 B lymphocyte") -AnnotationAssertion( "B2 B-cell") -AnnotationAssertion( "B2 B-lymphocyte") -AnnotationAssertion( "B2 cell") -AnnotationAssertion( "B-0 B cell") -AnnotationAssertion(rdfs:comment "B-2 B cells are reportedly CD48-positive, CD244-negative, and CD352-positive.") -AnnotationAssertion(rdfs:label "B-2 B cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - # Class: (pro-B cell) AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:dsd") Annotation( "ISBN:0781735149") Annotation( "PMID:12633665") Annotation( "PMID:16551251") Annotation( "PMID:18432934") "A progenitor cell of the B cell lineage, with some lineage specific activity such as early stages of recombination of B cell receptor genes, but not yet fully committed to the B cell lineage until the expression of PAX5 occurs.") @@ -34528,7 +17949,6 @@ AnnotationAssertion(Annotation( ) AnnotationAssertion(rdfs:comment "Human pro-B cells are reportedly CD10-positive, CD22-positive, CD34-positive, CD38-positive, CD45-low, CD48-positive, CD79a-positive, CD127-positive, CD184-positive, RAG-positive, TdT-positive, Vpre-B-positive, pre-BCR-negative, IgD-negative, and IgM-negative. Transcription factors expressed: Pax5-positive, EBF-positive, E2A-negative, Ikaros-negative, and PU.1-negative.") AnnotationAssertion(rdfs:label "pro-B cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) SubClassOf( ObjectSomeValuesFrom( )) @@ -34541,38 +17961,9 @@ AnnotationAssertion( "DN1 thymocyte") AnnotationAssertion( "TN1 cell") AnnotationAssertion(rdfs:label "pro-T cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (thromboblast) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:tfm") Annotation( "PMID:7758949") "A progenitor cell of the thrombocyte, a nucleated blood cell involved in coagulation typically seen in birds and other non-mammalian vertebrates.") -AnnotationAssertion(rdfs:comment "Note that this is a non-mammalian cell type.") -AnnotationAssertion(rdfs:label "thromboblast") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (neutrophil progenitor cell) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:tfm") Annotation( "ISBN:0721601464") "A progenitor cell of the neutrophil lineage.") -AnnotationAssertion( "neutrophil stem cell") -AnnotationAssertion(rdfs:label "neutrophil progenitor cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (myeloblast) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0721601464") Annotation( "http://en.wikipedia.org/wiki/Myeloblast") Annotation( "http://www.cap.org") "The most primitive precursor in the granulocytic series, having fine, evenly distributed chromatin, several nucleoli, a high nuclear-to-cytoplasmic ration (5:1-7:1), and a nongranular basophilic cytoplasm. They reside in the bone marrow.") -AnnotationAssertion( "BTO:0000187") -AnnotationAssertion( "FMA:83524") -AnnotationAssertion(rdfs:label "myeloblast") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (hematopoietic multipotent progenitor cell) AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:tfm") Annotation( "PMID:19022770") "A hematopoietic multipotent progenitor cell is multipotent, but not capable of long-term self-renewal. These cells are characterized as lacking lineage cell surface markers and being CD34-positive in both mice and humans.") @@ -34585,7 +17976,6 @@ AnnotationAssertion( ) AnnotationAssertion(rdfs:comment "Markers differ between mouse and human.") AnnotationAssertion(rdfs:label "hematopoietic multipotent progenitor cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) @@ -34600,7 +17990,6 @@ AnnotationAssertion( "FMA:70338") AnnotationAssertion(rdfs:comment "Note that this is a class of cell types, not an identified single cell type.") AnnotationAssertion(rdfs:label "lymphoid lineage restricted progenitor cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) DisjointClasses( ) @@ -34613,81 +18002,8 @@ AnnotationAssertion( "FMA:70339") AnnotationAssertion(rdfs:comment "Note that this is a class of cell types, not an identified single cell type.") AnnotationAssertion(rdfs:label "myeloid lineage restricted progenitor cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) -# Class: (mononuclear cell) - -AnnotationAssertion(Annotation( "GOC:add") "A leukocyte with a single non-segmented nucleus in the mature form.") -AnnotationAssertion( "BTO:0000878") -AnnotationAssertion( "CALOHA:TS-0768") -AnnotationAssertion( "FMA:86713") -AnnotationAssertion( "mononuclear leukocyte") -AnnotationAssertion( "peripheral blood mononuclear cell") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "mononuclear cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (follicular B cell) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:dsd") Annotation( "ISBN:0781735149") Annotation( "PMCID:PMC2193793") Annotation( "PMID:20933013") Annotation( "http://en.wikipedia.org/wiki/Follicular_B_Cells") "A resting mature B cell that has the phenotype IgM-positive, IgD-positive, CD23-positive and CD21-positive, and found in the B cell follicles of the white pulp of the spleen or the corticol areas of the peripheral lymph nodes. This cell type is also described as being CD19-positive, B220-positive, AA4-negative, CD43-negative, and CD5-negative.") -AnnotationAssertion( "Fo B cell") -AnnotationAssertion( "Fo B-cell") -AnnotationAssertion( "follicular B lymphocyte") -AnnotationAssertion( "follicular B-cell") -AnnotationAssertion( "follicular B-lymphocyte") -AnnotationAssertion(rdfs:comment "Follicular B cells are also reportedly CD48-positive, CD84-positive, CD229-positive, and CD352-positive.") -AnnotationAssertion(rdfs:label "follicular B cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (germinal center B cell) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:dsd") Annotation( "GOC:tfm") Annotation( "ISBN:0781735149") Annotation( "PMID:19447676") Annotation( "PMID:20933013") "A rapidly cycling mature B cell that has distinct phenotypic characteristics and is involved in T-dependent immune responses and located typically in the germinal centers of lymph nodes. This cell type expresses Ly77 after activation.") -AnnotationAssertion( ) -AnnotationAssertion( "GC B cell") -AnnotationAssertion( "GC B lymphocyte") -AnnotationAssertion( "GC B-cell") -AnnotationAssertion( "GC B-lymphocyte") -AnnotationAssertion( "germinal center B lymphocyte") -AnnotationAssertion( "germinal center B-cell") -AnnotationAssertion( "germinal center B-lymphocyte") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "Germinal center B cells are also reportedly CD10-positive, CD19-positive, CD20-positive, CD38-positive, CD44-low, CD45-positive, CD48-positive, CD95-positive, CD352-positive, and HLA-DR-positive. Transcription factors: BCL6-positive, Ets1-positive, IRF8-positive, MTA3-positive, OBF1-positive, PAX5-positive, SpiB-positive, and STAT3-positive.") -AnnotationAssertion(rdfs:label "germinal center B cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (marginal zone B cell of spleen) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:dsd") Annotation( "ISBN:0781735149") Annotation( "PMID:10933592") Annotation( "PMID:20933013") Annotation( "http://en.wikipedia.org/wiki/Marginal-zone_B_cell") "A mature B cell that is located in the marginal zone of the spleen with the phenotype CD23-negative and CD21-positive and expressing a B cell receptor usually reactive to bacterial cell wall components or senescent self components such as oxidized-LDL. This cell type is also described as being CD19-positive, B220-positive, IgM-high, AA4-negative, CD35-high.") -AnnotationAssertion( ) -AnnotationAssertion( "MZ B cell") -AnnotationAssertion( "MZ B lymphocyte") -AnnotationAssertion( "MZ B-cell") -AnnotationAssertion( "MZ B-lymphocyte") -AnnotationAssertion( "marginal zone B cell") -AnnotationAssertion( "marginal zone B lymphocyte") -AnnotationAssertion( "marginal zone B-cell") -AnnotationAssertion( "marginal zone B-lymphocyte") -AnnotationAssertion( "B cell of marginal zone of spleen") -AnnotationAssertion( "marginal zone of spleen B cell") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "MZ B cells are reportedly CD1-positive (mice), CD20-positive, CD48-positive, CD84-positive, CD150-positive, CD229-positive, and CD352-positive.") -AnnotationAssertion(rdfs:label "marginal zone B cell of spleen") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (ciliated olfactory receptor neuron) - -AnnotationAssertion(Annotation( "PMID:16841163") "An olfactory receptor cell in which the apical ending of the dendrite is a pronounced ciliated olfactory knob.") -AnnotationAssertion( "ciliated olfactory sensory neuron") -AnnotationAssertion( "ciliated sensory neuron") -AnnotationAssertion(rdfs:label "ciliated olfactory receptor neuron") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (microvillous olfactory receptor neuron) AnnotationAssertion(Annotation( "PMID:16841163") "An olfactory receptor cell in which the apical ending of the dendrite is a knob that bears numerous microvilli.") @@ -34696,19 +18012,6 @@ AnnotationAssertion( "microvillous olfactory receptor neuron") SubClassOf( ) -# Class: (serotonergic neuron) - -AnnotationAssertion(Annotation( "SANBI:mhl") "A neuron that releases serotonin as a neurotransmitter.") -AnnotationAssertion( "FBbt:00005133") -AnnotationAssertion( "MESH:D059326") -AnnotationAssertion( "WBbt:0006837") -AnnotationAssertion( "5-HT neuron") -AnnotationAssertion( "5-hydroxytryptamine neuron") -AnnotationAssertion( "serotinergic neuron") -AnnotationAssertion(rdfs:label "serotonergic neuron") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - # Class: (olfactory epithelial supporting cell) AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "ISBN:0517223651") Annotation( "SANBI:mhl") "Olfactory epithelial support cell is a columnar cell that extends from the epithelial free margin to the basement membrane of the olfactory epithelium. This cell type has a large, vertically, elongate, euchromatic nucleus, along with other nuclei, forms a layer superficial to the cell body of the receptor cell; sends long somewhat irregular microvilli into the mucus layer; at the base, with expanded end-feet containing numerous lamellated dense bodies resembling lipofuscin of neurons.") @@ -34718,7 +18021,6 @@ AnnotationAssertion( "supporting cell of olfactory epithelium") AnnotationAssertion( "sustentaculocyte of olfactory epithelium") AnnotationAssertion(rdfs:label "olfactory epithelial supporting cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) @@ -34734,33 +18036,17 @@ SubClassOf( "SANBI:mhl") "Neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface.") AnnotationAssertion(rdfs:label "neuromast hair cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) # Class: (slow muscle myoblast) AnnotationAssertion(Annotation( "SANBI:mhl") "A skeletal muscle myoblast that differentiates into slow muscle fibers.") AnnotationAssertion(rdfs:label "slow muscle myoblast") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) # Class: (fast muscle myoblast) AnnotationAssertion(Annotation( "SANBI:mhl") "A skeletal muscle myoblast that differentiates into fast muscle fibers.") AnnotationAssertion(rdfs:label "fast muscle myoblast") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (classical monocyte) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GO_REF:0000031") Annotation( "PMID:16322748") Annotation( "PMID:18303997") Annotation( "PMID:20628149") Annotation( "PMID:20870168") "A monocyte that responds rapidly to microbial stimuli by secreting cytokines and antimicrobial factors and which is characterized by high expression of CCR2 in both rodents and humans, negative for the lineage markers CD3, CD19, and CD20, and of larger size than non-classical monocytes.") -AnnotationAssertion( ) -AnnotationAssertion( "inflammatory monocyte") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "Markers: CCR2+CXCCR1 (human, mouse, rat).") -AnnotationAssertion(rdfs:label "classical monocyte") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) # Class: (tissue-resident macrophage) @@ -34770,7 +18056,6 @@ AnnotationAssertion( "fixed macrophage") AnnotationAssertion( "resting histiocyte") AnnotationAssertion(rdfs:label "tissue-resident macrophage") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) # Class: (central nervous system macrophage) @@ -34778,7 +18063,6 @@ SubClassOf(Annotation( AnnotationAssertion(Annotation( "GO_REF:0000031") Annotation( "PMID:16322748") "A tissue-resident macrophage found in the central nervous system.") AnnotationAssertion( "CNS macrophage") AnnotationAssertion(rdfs:label "central nervous system macrophage") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) # Class: (perivascular macrophage) @@ -34786,19 +18070,9 @@ SubClassOf(Annotation( AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "GO_REF:0000031") Annotation( "PMID:16507898") "A central nervous system macrophage found in small blood vessels in the brain. Markers include CD14+CD16+CD163+.") AnnotationAssertion(rdfs:comment "Markers: Human/monkey, mice: CD163. Human: CD14+CD16+CD163+.") AnnotationAssertion(rdfs:label "perivascular macrophage") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) SubClassOf( ) -# Class: (myeloid suppressor cell) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:ana") Annotation( "GO_REF:0000031") Annotation( "PMID:16168663") Annotation( "PMID:17016554") Annotation( "PMID:17016559") "An immature myeloid leukocyte of heterogeneous phenotype found particularly in cancer and sepsis patients that is capable of suppressing activity of T cells in ex vivo assays. This cell type is CD45-positive, CD11b-positive.") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "Markers: Mouse: CD11b+GR1+CD31+; Human: CD34+ CD33+CD15-CD13+. (According to some reports in humans these cells are iNOS+ARG1+IL13+IFNg+); location: In cancerous tissue; in the blood and lymphoid organs in sepsis.") -AnnotationAssertion(rdfs:label "myeloid suppressor cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - # Class: (thymocyte) AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:tfm") Annotation( "GO_REF:0000031") Annotation( "PMID:12415312") "An immature T cell located in the thymus.") @@ -34813,46 +18087,8 @@ AnnotationAssertion( "XAO:0003159") AnnotationAssertion( "thymic lymphocyte") AnnotationAssertion(rdfs:label "thymocyte") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) -# Class: (DN1 thymic pro-T cell) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:tfm") Annotation( "GO_REF:0000031") "A pro-T cell that has the phenotype CD4-negative, CD8-negative, CD44-positive, and CD25-negative.") -AnnotationAssertion( "DN1 thymic pro-T lymphocyte") -AnnotationAssertion( "DN1 thymic pro-T-cell") -AnnotationAssertion( "DN1 thymic pro-T-lymphocyte") -AnnotationAssertion( "DN1 thymic progenitor T cell") -AnnotationAssertion( "DN1 thymocyte") -AnnotationAssertion( "double negative 1") -AnnotationAssertion( "preT.DN1.Th") -AnnotationAssertion(rdfs:label "DN1 thymic pro-T cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (early lymphoid progenitor) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:dsd") Annotation( "GOC:pam") Annotation( "GOC:tfm") Annotation( "GO_REF:0000031") Annotation( "PMID:19022770") "A lymphoid progenitor cell that is found in bone marrow, gives rise to B cells, T cells, natural killer cells and dendritic cells, and has the phenotype Lin-negative, Kit-positive, Sca-1-positive, FLT3-positive, CD34-positive, CD150 negative, and GlyA-negative.") -AnnotationAssertion( "lymphoid-primed multipotent progenitor") -AnnotationAssertion(Annotation( ) "ELP") -AnnotationAssertion(Annotation( "PMID:18371378") Annotation( ) "GMLP") -AnnotationAssertion(Annotation( ) "LMPP") -AnnotationAssertion(rdfs:comment "Markers are associated with mouse cells. ELP transcription factors include E2A-positive, Ikaros-positive, EBF-negative, Pax5-negative, PU.1-negative.") -AnnotationAssertion(rdfs:label "early lymphoid progenitor") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (thymic conventional dendritic cell) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:pam") Annotation( "GO_REF:0000031") Annotation( "PMID:19273629") "A dendritic cell arising in thymus that has the phenotype CD11c-positive, CD11b-negative, and CD45RA-negative.") -AnnotationAssertion(rdfs:comment "In the mouse this cell expresses CD8-alpha-alpha.") -AnnotationAssertion(rdfs:label "thymic conventional dendritic cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (lymphocyte of B lineage) AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:rhs") Annotation( "GOC:tfm") Annotation( "GO_REF:0000031") Annotation( "ISBN:0781735149") "A lymphocyte of B lineage with the commitment to express an immunoglobulin complex.") @@ -34863,48 +18099,12 @@ AnnotationAssertion(rdfs:label "lymp SubClassOf(Annotation( "true") ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (antibody secreting cell) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:tfm") Annotation( "GO_REF:0000031") Annotation( "ISBN:0721601464") Annotation( "ISBN:0781735149") "A lymphocyte of B lineage that is devoted to secreting large amounts of immunoglobulin.") -AnnotationAssertion(rdfs:label "antibody secreting cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (IgE memory B cell) - -AnnotationAssertion(Annotation( "GOC:rhs") Annotation( "GO_REF:0000031") Annotation( "ISBN:0781765196") "A class switched memory B cell that expresses IgE on the cell surface.") -AnnotationAssertion( "IgE memory B lymphocyte") -AnnotationAssertion( "IgE memory B-cell") -AnnotationAssertion( "IgE memory B-lymphocyte") -AnnotationAssertion( "memory IgE B cell") -AnnotationAssertion( "memory IgE B lymphocyte") -AnnotationAssertion( "memory IgE B-cell") -AnnotationAssertion( "memory IgE B-lymphocyte") -AnnotationAssertion(rdfs:label "IgE memory B cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (preBCR-positive large pre-B-II cell) - -AnnotationAssertion(Annotation( "GOC:rhs") Annotation( "GOC:tfm") Annotation( "GO_REF:0000031") Annotation( "PMID:9785673") "An preBRC-positive large pre-B-II cell is a large pre-B-II cell that is pre-B cell receptor-positive, composed of surrogate light chain protein (SL), which is composed of VpreB , Lambda 5/14.1, in complex with immunoglobulin mu heavy chain (IgHmu) on the cell surface.") -AnnotationAssertion(rdfs:label "preBCR-positive large pre-B-II cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (preBCR-negative large pre-B-II cell) - -AnnotationAssertion(Annotation( "GOC:rhs") Annotation( "GOC:tfm") Annotation( "GO_REF:0000031") Annotation( "PMID:9785673") "A pre-BCR-negative large pre-B-II cell is a large pre-B-II cell that is pre-B cell receptor-negative, composed of surrogate light chain protein (SL), which is composed of VpreB and Lambda 5/14.1, in complex with immunoglobulin mu heavy chain (IgHmu), on the cell surface, and lack a DNA rearrangement of immunoglobulin light chain genes.") -AnnotationAssertion(rdfs:label "preBCR-negative large pre-B-II cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - # Class: (small pre-B-II cell) AnnotationAssertion(Annotation( "GOC:dsd") Annotation( "GOC:rhs") Annotation( "GOC:tfm") Annotation( "GO_REF:0000031") Annotation( "PMID:16551251") Annotation( "PMID:18432934") Annotation( "PMID:9785673") "A small pre-B-II cell is a pre-B-II cell that is Rag1-positive, Rag2-positive, pre-BCR-negative, and BCR-negative, is not proliferating, and carries a DNA rearrangement of one or more immunoglobulin light chain genes.") AnnotationAssertion( "small pre-BII cell") AnnotationAssertion(rdfs:comment "Small pre-B-II cells are also reportedly CD10-positive, CD19-positive, CD34-negative, CD79a-positive, CD127-negative, TdT-negative, Vpre-B-negative, sIgM-negative, and sIgD-negative. Transcription factors: PU.1-positive, Ikaros-positive, E2A-positive, and PAX5-positive.") AnnotationAssertion(rdfs:label "small pre-B-II cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) # Class: (pre-B-II cell) @@ -34916,220 +18116,8 @@ AnnotationAssertion( "pre-BII cell") AnnotationAssertion(rdfs:comment "pre-B-II cell are also reportedly CD19-positive, CD22-positive, CD38-positive, CD45-positive, and CD48-positive.") AnnotationAssertion(rdfs:label "pre-B-II cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) SubClassOf( ObjectSomeValuesFrom( )) -DisjointClasses( ) - -# Class: (pre-B-I cell) - -AnnotationAssertion(Annotation( "GOC:dsd") Annotation( "GOC:rhs") Annotation( "GOC:tfm") Annotation( "GO_REF:0000031") Annotation( "PMID:16551251") Annotation( "PMID:18432934") Annotation( "PMID:20839338") Annotation( "PMID:9785673") "A pre-B-I cell is a precursor B cell that expresses CD34 and surrogate immunoglobulin light chain (VpreB , Lambda 5 (mouse)/14.1 (human)) on the cell surface, and TdT, Rag1,and Rag2 intracellularly. Cell type carries a D-JH DNA rearrangement, and lacks expression of immunglobulin heavy chain protein.") -AnnotationAssertion( "pre-BI cell") -AnnotationAssertion(Annotation( "PMID:11244048") "pro-B cell (Philadelphia nomenclature)") -AnnotationAssertion(rdfs:comment "Human pre-B-I cells are reportedly CD10-positive, CD19-positive, CD22-positive, CD38-positive, CD45-low, CD79a-positive, CD127-negative, pre-BCR-negative, IgM-negative, IgD-negative, and Tdt-positive. Transcription factors expressed: Pax5-positive.") -AnnotationAssertion(rdfs:label "pre-B-I cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (large pre-B-II cell) - -AnnotationAssertion(Annotation( "GOC:dsd") Annotation( "GOC:rhs") Annotation( "GO_REF:0000031") Annotation( "PMID:16551251") Annotation( "PMID:18432934") Annotation( "PMID:9785673") "A large pre-B-II cell is a pre-B-II cell that is proliferating and is Rag1-negative and Rag2-negative.") -AnnotationAssertion(Annotation( "PMID:11244048") "large pre-B cell") -AnnotationAssertion( "large pre-BII cell") -AnnotationAssertion(rdfs:comment "Large pre-B-II cells are also reportedly CD10-positive, CD19-positive, CD34-negative, CD79a-positive, CD127-negative, TdT-negative, Vpre-B-positive, pre-BCR-positive, sIgM-negative, and sIgD-negative. Transcription factors: PU.1-positive, Ikaros-positive, E2A-positive, and PAX5-positive.") -AnnotationAssertion(rdfs:label "large pre-B-II cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (Bm1 B cell) - -AnnotationAssertion(Annotation( "GOC:dsd") Annotation( "GOC:msz") Annotation( "GO_REF:0000031") Annotation( "PMID:17992590") Annotation( "PMID:18432934") Annotation( "PMID:8006591") "A follicular B cell that is IgD-positive, CD23-negative, and CD38-negative. This naive cell type is activated in the extrafollicular areas through interaction with interdigitating dendritic cells and antigen-specific CD4-positive T cells.") -AnnotationAssertion( "Bm1 B lymphocyte") -AnnotationAssertion( "Bm1 B-cell") -AnnotationAssertion( "Bm1 B-lymphocyte") -AnnotationAssertion(rdfs:comment "These cells are also reportedly CD10-negative, CD39-positive, CD44-positive, CD71-negative, CD77-negative, IgM-positive, IgG-negative, IgA-negative, and IgE-negative.") -AnnotationAssertion(rdfs:label "Bm1 B cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (Bm2 B cell) - -AnnotationAssertion(Annotation( "GOC:dsd") Annotation( "GOC:msz") Annotation( "GO_REF:0000031") Annotation( "PMID:17992590") Annotation( "PMID:18432934") Annotation( "PMID:8006591") "A follicular B cell that is IgD-positive and CD23-positive and CD38-positive. This naive cell type is activated in the extrafollicular areas via interaction with dendritic cells and antigen specific T cells.") -AnnotationAssertion( "Bm2 B lymphocyte") -AnnotationAssertion( "Bm2 B-cell") -AnnotationAssertion( "Bm2 B-lymphocyte") -AnnotationAssertion(rdfs:comment "These cells are also CD10-negative, CD39-positive, CD44-positive, CD71-negative, CD77-negative, IgM-positive, IgG-negative, IgA-negative, and IgE-negative.") -AnnotationAssertion(rdfs:label "Bm2 B cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (Bm3-delta B cell) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:msz") Annotation( "GOC:tfm") Annotation( "GO_REF:0000031") Annotation( "PMID:9280752") "A germinal center B cell that develops from a Bm3 B cell. This cell has the phenotype IgM-negative, IgD-positive, and CD38-positive.") -AnnotationAssertion( "Bm3-delta B lymphocyte") -AnnotationAssertion( "Bm3-delta B-cell") -AnnotationAssertion( "Bm3-delta B-lymphocyte") -AnnotationAssertion(rdfs:label "Bm3-delta B cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (Bm2' B cell) - -AnnotationAssertion(Annotation( "GOC:dsd") Annotation( "GOC:msz") Annotation( "GOC:tfm") Annotation( "GO_REF:0000031") Annotation( "PMID:17992590") Annotation( "PMID:18432934") Annotation( "PMID:8006591") "A germinal center B cell that founds a germinal center, and has the phenotype IgD-positive, CD38-positive, and CD23-negative.") -AnnotationAssertion( "Bm2' B lymphocyte") -AnnotationAssertion( "Bm2' B-cell") -AnnotationAssertion( "Bm2-prime B cell") -AnnotationAssertion( "Bm2-prime B-lymphocyte") -AnnotationAssertion( "germinal center founder cell") -AnnotationAssertion(rdfs:comment "Bm2' B cells are also reportedly CD10-positive, CD39-negative, CD44-negative, CD71-positive, CD77-negative, IgM-positive, IgG-negative, IgA-negative, and IgE-negative.") -AnnotationAssertion(rdfs:label "Bm2' B cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (Bm3 B cell) - -AnnotationAssertion(Annotation( "GOC:dsd") Annotation( "GOC:msz") Annotation( "GO_REF:0000031") Annotation( "PMID:18432934") Annotation( "PMID:8006591") "A germinal center B cell that is rapidly dividing and has the phenotype IgD-negative, CD38-positive, and CD77-positive. Somatic hypermutation of the immunoglobulin V gene region can occur during proliferation of this cell type.") -AnnotationAssertion( "Bm3 B lymphocyte") -AnnotationAssertion( "Bm3 B-cell") -AnnotationAssertion( "Bm3 B-lymphocyte") -AnnotationAssertion(Annotation( "PMID:8006591") "centroblast") -AnnotationAssertion(rdfs:comment "Bm3 B cells are also reportedly CD10-positive, CD23-negative, CD39-negative, CD44-negative, CD71-positive, and CD77-positive.") -AnnotationAssertion(rdfs:label "Bm3 B cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (Bm4 B cell) - -AnnotationAssertion(Annotation( "GOC:dsd") Annotation( "GOC:msz") Annotation( "GO_REF:0000031") Annotation( "PMID:18432934") Annotation( "PMID:8006591") "A germinal center B cell that has the phenotype CD77-negative, IgD-negative, and CD38-positive. These cells have undergone somatic mutation of the B cell receptor.") -AnnotationAssertion( "Bm4 B lymphocyte") -AnnotationAssertion( "Bm4 B-cell") -AnnotationAssertion( "Bm4 B-lymphocyte") -AnnotationAssertion(Annotation( "PMID:17992590") "centrocyte") -AnnotationAssertion(rdfs:comment "Bm4 B cells are also reportedly CD10-positive, CD23-negative, CD39-negative, CD44-positive, and CD71-positive.") -AnnotationAssertion(rdfs:label "Bm4 B cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (Bm5 B cell) - -AnnotationAssertion(Annotation( "GOC:dsd") Annotation( "GOC:msz") Annotation( "GOC:tfm") Annotation( "GO_REF:0000031") Annotation( "PMID:18432934") Annotation( "PMID:8006591") "A memory B cell arising in the germinal center that is IgD-negative and has undergone somatic mutation of the variable region of the immunoglobulin heavy and light chain genes.") -AnnotationAssertion( "Bm5 B lymphocyte") -AnnotationAssertion( "Bm5 B-cell") -AnnotationAssertion( "Bm5 B-lymphocyte") -AnnotationAssertion(rdfs:comment "Bm5 B cells are also reportedly CD10-positive, CD23-negative, CD38-negative, CD39-positive, CD44-positive, CD71-positive, and CD77-negative.") -AnnotationAssertion(rdfs:label "Bm5 B cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (unswitched memory B cell) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:dsd") Annotation( "GOC:rhs") Annotation( "GO_REF:0000031") Annotation( "ISBN:0781765196") Annotation( "PMID:20933013") Annotation( "PMID:22343568") "An unswitched memory B cell is a memory B cell that has the phenotype IgM-positive, IgD-positive, CD27-positive, CD138-negative, IgG-negative, IgE-negative, and IgA-negative.") -AnnotationAssertion( ) -AnnotationAssertion(Annotation( "PMID:22343568") "IgD+ memory B cell") -AnnotationAssertion(Annotation( "HP:0032126") "non-class-switched memory B cell") -AnnotationAssertion( "unswitched memory B lymphocyte") -AnnotationAssertion( "unswitched memory B-cell") -AnnotationAssertion( "unswitched memory B-lymphocyte") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "This cell type is compatible with the HIPC Lyoplate markers for 'IgD+ memory B cell'. Per DSD: Unswitched memory B cells are also reportedly CD48-positive, CD84-positive, CD229-positive, and CD352-positive.") -AnnotationAssertion(rdfs:label "unswitched memory B cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (IgM memory B cell) - -AnnotationAssertion(Annotation( "GOC:dsd") Annotation( "GOC:rhs") Annotation( "GO_REF:0000031") Annotation( "ISBN:0781765196") Annotation( "PMID:19447676") "An IgM memory B cell is an unswitched memory B cell with the phenotype IgM-positive and IgD-negative.") -AnnotationAssertion( "IgM memory B lymphocyte") -AnnotationAssertion( "IgM memory B-cell") -AnnotationAssertion( "IgM memory B-lymphocyte") -AnnotationAssertion( "memory IgM B cell") -AnnotationAssertion( "memory IgM B lymphocyte") -AnnotationAssertion( "memory IgM B-cell") -AnnotationAssertion( "memory IgM B-lymphocyte") -AnnotationAssertion(rdfs:comment "IgM memory B cells are also reportedly CD1c-positive, CD95-positive, CD80-positive, CD84-positive, CD86-positive, CD150-negative, CD229-positive, CD289-positive, and CD290-positive. Transcription factors: Notch2-positive, PAX5-positive, SpiB-positive, Ets1-positive, and OBF1-positive.") -AnnotationAssertion(rdfs:label "IgM memory B cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (class switched memory B cell) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:dsd") Annotation( "GOC:rhs") Annotation( "GO_REF:0000031") Annotation( "ISBN:0781765196") Annotation( "PMID:20933013") Annotation( "PMID:9295047") "A class switched memory B cell is a memory B cell that has undergone Ig class switching and therefore is IgM-negative on the cell surface. These cells are CD27-positive and have either IgG, IgE, or IgA on the cell surface.") -AnnotationAssertion( ) -AnnotationAssertion( "class switched memory B lymphocyte") -AnnotationAssertion( "class switched memory B-cell") -AnnotationAssertion( "class switched memory B-lymphocyte") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "Per DSD: Class switched memory B cells are also reportedly CD48-positive, CD229-positive, and CD352-positive.") -AnnotationAssertion(rdfs:label "class switched memory B cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (IgA memory B cell) - -AnnotationAssertion(Annotation( "GOC:dsd") Annotation( "GOC:msz") Annotation( "GO_REF:0000031") Annotation( "ISBN:0781765196") "A class switched memory B cell that expresses IgA.") -AnnotationAssertion( "IgA memory B lymphocyte") -AnnotationAssertion( "IgA memory B-cell") -AnnotationAssertion( "IgA memory B-lymphocyte") -AnnotationAssertion( "memory IgA B cell") -AnnotationAssertion( "memory IgA B lymphocyte") -AnnotationAssertion( "memory IgA B-cell") -AnnotationAssertion( "memory IgA B-lymphocyte") -AnnotationAssertion(rdfs:comment "IgA memory B cell are also reportedly RORalpha-positive.") -AnnotationAssertion(rdfs:label "IgA memory B cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (IgG memory B cell) - -AnnotationAssertion(Annotation( "GOC:rhs") Annotation( "GO_REF:0000031") Annotation( "ISBN:0781765196") "An IgG memory B cell is a class switched memory B cell that is class switched and expresses IgG on the cell surface.") -AnnotationAssertion( "IgG memory B lymphocyte") -AnnotationAssertion( "IgG memory B-cell") -AnnotationAssertion( "IgG memory B-lymphocyte") -AnnotationAssertion( "memory IgG B cell") -AnnotationAssertion( "memory IgG B lymphocyte") -AnnotationAssertion( "memory IgG B-cell") -AnnotationAssertion( "memory IgG B-lymphocyte") -AnnotationAssertion(rdfs:label "IgG memory B cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (plasmablast) - -AnnotationAssertion(Annotation( "GOC:dsd") Annotation( "GOC:msz") Annotation( "GOC:tfm") Annotation( "GO_REF:0000031") Annotation( "PMCID:PMC2673126") "An activated mature (naive or memory) B cell that is secreting immunoglobulin, typified by being CD27-positive, CD38-positive, CD138-negative.") -AnnotationAssertion( ) -AnnotationAssertion( "CD20-negative B cell") -AnnotationAssertion( "FMA:84371") -AnnotationAssertion( "CD27-positive, CD38-positive, CD20-negative B cell") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "This cell type is compatible with the HIPC Lyoplate markers for 'plasmablast'. Plasmablasts are also reportedly CD48-positive, CD63-positive, CD229-positive, CD270-positive, CD319-positive, CD352-positive, CD361-positive, and IgD-negative.") -AnnotationAssertion(rdfs:label "plasmablast") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (double negative memory B cell) - -AnnotationAssertion(Annotation( "GOC:msz") Annotation( "GOC:tfm") Annotation( "GO_REF:0000031") "A memory B cell with the phenotype IgD-negative and CD27-negative.") -AnnotationAssertion( "dn memory B cell") -AnnotationAssertion( "dn memory B lymphocyte") -AnnotationAssertion( "dn memory B-cell") -AnnotationAssertion( "dn memory B-lymphocyte") -AnnotationAssertion( "double negative memory B lymphocyte") -AnnotationAssertion( "double negative memory B-cell") -AnnotationAssertion( "double negative memory B-lymphocyte") -AnnotationAssertion(rdfs:label "double negative memory B cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) # Class: (hematopoietic cell) @@ -35142,8 +18130,7 @@ AnnotationAssertion( "haemopoietic cell") AnnotationAssertion( "hemopoietic cell") AnnotationAssertion(rdfs:label "hematopoietic cell") -SubClassOf( ) -SubClassOf( ) +SubClassOf( ) # Class: (conventional dendritic cell) @@ -35160,147 +18147,8 @@ AnnotationAssertion( ) AnnotationAssertion(rdfs:comment "Originally described in the dendritic cell ontology (DC_CL:0000003)(PMID:19243617) These cells are also CD20-negative, MHCII-positive.") AnnotationAssertion(rdfs:label "conventional dendritic cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) -# Class: (CD34-positive, CD38-positive common myeloid progenitor OR CD34-positive, CD38-positive common lymphoid progenitor) - -AnnotationAssertion( "CD71-positive common myeloid precursor OR CD7-negative lymphoid precursor OR CD7-positive lymphoid") -AnnotationAssertion(rdfs:comment "Originally described in the dendritic cell ontology (DC_CL:1100000)(PMID:19243617).") -AnnotationAssertion(rdfs:label "CD34-positive, CD38-positive common myeloid progenitor OR CD34-positive, CD38-positive common lymphoid progenitor") -EquivalentClasses( ObjectUnionOf( )) -SubClassOf( ) - -# Class: (Kit and Sca1-positive hematopoietic stem cell) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:amm") Annotation( "GOC:tfm") Annotation( "GO_REF:0000031") Annotation( "PMID:17952047") Annotation( "PMID:19022770") "A hematopoietic stem cell that has plasma membrane part Kit-positive, SCA-1-positive, CD150-positive and CD34-negative.") -AnnotationAssertion( "LSK stem cell") -AnnotationAssertion( "Sca1-positive hematopoietic stem cell") -AnnotationAssertion(rdfs:comment "Cell markers are associated with mouse hematopoietic stem cell. Originally described in the dendritic cell ontology (DC_CL:0000043)(PMID:19243617).") -AnnotationAssertion(rdfs:label "Kit and Sca1-positive hematopoietic stem cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -DisjointClasses( ) - -# Class: (CD7-negative lymphoid progenitor OR granulocyte monocyte progenitor) - -AnnotationAssertion(rdfs:comment "Originally described in the dendritic cell ontology (DC_CL:1110000)(PMID:19243617).") -AnnotationAssertion(rdfs:label "CD7-negative lymphoid progenitor OR granulocyte monocyte progenitor") -EquivalentClasses( ObjectUnionOf( )) -SubClassOf( ) - -# Class: (CD115-positive monocyte OR common dendritic progenitor) - -AnnotationAssertion(rdfs:comment "Originally described in the dendritic cell ontology (DC_CL:1111000)(PMID:19243617).") -AnnotationAssertion(rdfs:label "CD115-positive monocyte OR common dendritic progenitor") -EquivalentClasses( ObjectUnionOf( )) -SubClassOf( ) - -# Class: (CD34-positive, CD38-positive common lymphoid progenitor) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:amm") Annotation( "GOC:tfm") Annotation( "GO_REF:0000031") Annotation( "PMCID:PMC2346585") Annotation( "PMID:19022770") "A common lymphoid progenitor that is CD10-positive, CD45RA-positive, CD34-positive and CD38-positive.") -AnnotationAssertion( "CD10-positive common lymphocyte precursor") -AnnotationAssertion( "CD10-positive common lymphocyte progenitor") -AnnotationAssertion( "CD10-positive common lymphoid precursor") -AnnotationAssertion(rdfs:comment "These markers are associated with human common lymphoid progenitors. Originally described in the dendritic cell ontology (DC_CL:0000032)(PMID:19243617).") -AnnotationAssertion(rdfs:label "CD34-positive, CD38-positive common lymphoid progenitor") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) -DisjointClasses( ) - -# Class: (CD115-positive monocyte) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:amm") Annotation( "GO_REF:0000031") Annotation( "PMID:17952047") "CD115-positive monocyte is a monocyte that is CD115-positive and CD11b-positive.") -AnnotationAssertion(rdfs:comment "These markers are associated with human cells. Originally described in the dendritic cell ontology (DC_CL:0000033)(PMID:19243617).") -AnnotationAssertion(rdfs:label "CD115-positive monocyte") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (Kit-positive, CD34-positive common myeloid progenitor) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:amm") Annotation( "GOC:tfm") Annotation( "GO_REF:0000031") Annotation( "PMID:1261582") Annotation( "PMID:17952047") Annotation( "http://www.immgen.org/index_content.html") "A common myeloid progenitor that is Kit-positive and CD34-positive, Il7ra-negative, and is SCA1-low and Fcgr2-low and Fcgr3-low.") -AnnotationAssertion( "CD117-positive common myeloid precursor") -AnnotationAssertion(rdfs:comment "Markers are associated with mouse cells. Originally described in the dendritic cell ontology (DC_CL:0000034)(PMID:19243617).") -AnnotationAssertion(rdfs:label "Kit-positive, CD34-positive common myeloid progenitor") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) -DisjointClasses( ) - -# Class: (CD34-positive, CD38-negative hematopoietic stem cell) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:amm") Annotation( "GOC:tfm") Annotation( "GO_REF:0000031") Annotation( "PMID:10430905") Annotation( "PMID:11750107") Annotation( "PMID:16551251") Annotation( "PMID:20024907") Annotation( "PMID:9389721") "CD133-positive hematopoietic stem cell is a hematopoietic stem cell that is CD34-positive, CD90-positive, and CD133-positive.") -AnnotationAssertion( "CALOHA:TS-0448") -AnnotationAssertion( "FMA:86475") -AnnotationAssertion(Annotation( "PMID:16140871") "CD133-positive hematopoietic stem cell") -AnnotationAssertion(rdfs:comment "Cell markers are associated with human hematopoietic stem cells. Originally described in the dendritic cell ontology (DC_CL:0000035)(PMID:19243617).") -AnnotationAssertion(rdfs:label "CD34-positive, CD38-negative hematopoietic stem cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (Kit-positive, Sca1-positive common lymphoid progenitor) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:amm") Annotation( "GOC:tfm") Annotation( "GO_REF:0000031") Annotation( "PMID:17952047") Annotation( "http://www.immgen.org/index_content.html") "A common lymphoid progenitor that is Kit-low, FLT3-positive, IL7ralpha-positive, and SCA1-low.") -AnnotationAssertion( "CD217-positive common lymphocyte precursor") -AnnotationAssertion( "CD217-positive common lymphocyte progenitor") -AnnotationAssertion( "CD217-positive common lymphoid precursor") -AnnotationAssertion(rdfs:comment "Markers are associated with mouse cells.") -AnnotationAssertion(rdfs:label "Kit-positive, Sca1-positive common lymphoid progenitor") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (CD34-positive, CD38-positive common myeloid progenitor) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:amm") Annotation( "GO_REF:0000031") Annotation( "PMCID:PMC2626675") Annotation( "PMID:16551251") "A common myeloid progenitor that is CD34-positive, CD38-positive, IL3ra-low, CD10-negative, CD7-negative, CD45RA-negative, and IL-5Ralpha-negative.") -AnnotationAssertion( "CD71-positive common myeloid precursor") -AnnotationAssertion(rdfs:comment "Markers are associated with human cell type. Originally described in the dendritic cell ontology (DC_CL:0000038)(PMID:19243617).") -AnnotationAssertion(rdfs:label "CD34-positive, CD38-positive common myeloid progenitor") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (CD7-negative lymphoid progenitor cell) - -AnnotationAssertion(Annotation( "GOC:amm") Annotation( "GO_REF:0000031") Annotation( "PMID:16551251") "CD7-negative lymphoid progenitor cell is a lymphoid progenitor cell that is CD34-positive, CD7-negative and CD45RA-negative.") -AnnotationAssertion( "CD7-negative lymphoid precursor") -AnnotationAssertion(rdfs:comment "These markers are associated with human cells. Originally described in the dendritic cell ontology (DC_CL:0000039)(PMID:19243617).") -AnnotationAssertion(rdfs:label "CD7-negative lymphoid progenitor cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (CD7-positive lymphoid progenitor cell) - -AnnotationAssertion(Annotation( "GOC:amm") Annotation( "GOC:tfm") Annotation( "GO_REF:0000031") Annotation( "PMID:16551251") Annotation( "PMID:19491395") "CD7-positive lymphoid progenitor cell is a lymphoid progenitor cell that is CD34-positive, CD7-positive and is CD45RA-negative.") -AnnotationAssertion( "CD7-positive lymphoid precursor") -AnnotationAssertion(rdfs:comment "These markers are associated with human cells. Originally described in the dendritic cell ontology (DC_CL:0000040)(PMID:19243617).") -AnnotationAssertion(rdfs:label "CD7-positive lymphoid progenitor cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (common dendritic progenitor) - -AnnotationAssertion(Annotation( "GOC:amm") Annotation( "GOC:tfm") Annotation( "GO_REF:0000031") Annotation( "PMID:16551251") Annotation( "PMID:17922016") Annotation( "PMID:19286519") "Common dendritic precursor is a hematopoietic progenitor cell that is CD117-low, CD135-positive, CD115-positive and lacks plasma membrane parts for hematopoietic lineage markers.") -AnnotationAssertion(Annotation( "PMID:21219184") "CDP") -AnnotationAssertion( "common dendritic precursor") -AnnotationAssertion(Annotation( "PMID:21219184") "pro-DCs") -AnnotationAssertion(rdfs:comment "Surface markers are for mouse cells. Originally described in the dendritic cell ontology (DC_CL:0000041) CDP are reportedly CD2-negative, CD3-negative, CD4-negative, CD5-negative, CD8a-negative, CD11c-positive, CD14-negative, CD19-negative, CD20-negative, CD56-negative, B220-negative, Ly6g-negative, MHCII-positive, and Ter119-negative. (PMID:19243617).") -AnnotationAssertion(rdfs:label "common dendritic progenitor") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (CD117-positive common myeloid progenitor OR CD217-positive common lymphoid progenitor) - -AnnotationAssertion(rdfs:comment "Originally described in the dendritic cell ontology (DC_CL:1111100)(PMID:19243617).") -AnnotationAssertion(rdfs:label "CD117-positive common myeloid progenitor OR CD217-positive common lymphoid progenitor") -EquivalentClasses( ObjectUnionOf( )) -SubClassOf( ) - # Class: (cerebellar granule cell) AnnotationAssertion(Annotation( "GOC:mah") Annotation( "doi:10.12688/f1000research.15021.1") Annotation( "doi:10.3389/fncir.2020.611841") "An excitatory granule cell with a soma located in the granular layer of cerebellar cortex. A mature cerebellar granule cell has short dendrites with a characteristic claw-like appearance and a long axon that ascends to the molecular layer where it bifurcates (except in non-teleost fish, where it does not bifurcate) and extends mediolaterally to form parallel fibers.") @@ -35308,21 +18156,13 @@ AnnotationAssertion( "doi:10.3389/fncir.2020.611841") "granule cell of the cerebellum") AnnotationAssertion(Annotation( "doi:10.3389/fncir.2020.611841") rdfs:comment "It has been noted in at least some mammalian species that granule cells are the most numerous cell type in the cerebellum and in the brain, with at least 99% of all cerebellar neurons being granule cells.") AnnotationAssertion(rdfs:label "cerebellar granule cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (cortical granule cell) - -AnnotationAssertion(Annotation( "GOC:mah") "Granule cell that is part of the cerebral cortex.") -AnnotationAssertion(rdfs:label "cortical granule cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (hippocampal granule cell) AnnotationAssertion(Annotation( "GOC:mah") "Granule cell with a soma found in the hippocampus.") AnnotationAssertion(rdfs:label "hippocampal granule cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (bone cell) @@ -35333,8 +18173,6 @@ AnnotationAssertion( AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "bone cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) # Class: (terminally differentiated osteoblast) @@ -35352,87 +18190,6 @@ AnnotationAssertion(rdfs:label "non- SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (IgD-negative memory B cell) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "PMID:22343568") "A memory B cell that lacks expression of surface IgD.") -AnnotationAssertion(Annotation( "PMID:22343568") "IgD- memory B cell") -AnnotationAssertion(rdfs:comment "This cell type is compatible with the HIPC Lyoplate markers for 'IgD- memory B cell'. The majority of these cells are class-switched, though some are IgM-positive.") -AnnotationAssertion(rdfs:label "IgD-negative memory B cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (CD14-positive monocyte) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "PMID:22343568") "A monocyte that expresses CD14 and is negative for the lineage markers CD3, CD19, and CD20.") -AnnotationAssertion( ) -AnnotationAssertion(Annotation( "PMID:22343568") "monocyte") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "This cell type is compatible with the HIPC Lyoplate markers for 'monocyte'. Note that while CD14 is considered a reliable marker for human monocytes, it is only expressed on approximately 85% of mouse monocytes.") -AnnotationAssertion(rdfs:label "CD14-positive monocyte") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (CD14-positive, CD16-low monocyte) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "PMID:20628149") "An intermediate monocyte that is CD14-positive and with low amounts of CD16.") -AnnotationAssertion( ) -AnnotationAssertion( "intermediate monocyte, human") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "Definition is valid for human intermediate monocytes.") -AnnotationAssertion(rdfs:label "CD14-positive, CD16-low monocyte") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (common myeloid progenitor, CD34-positive) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:dsd") Annotation( "GOC:tfm") Annotation( "ISBN:0878932437") Annotation( "PMCID:PMC2212039") Annotation( "PMID:10724173") Annotation( "PMID:16551251") Annotation( "PMID:16647566") "A progenitor cell committed to myeloid lineage, including the megakaryocyte and erythroid lineages. These cells are CD34-positive, and express Gata1, Gata2, C/EBPa, and Pu.1.") -AnnotationAssertion( "common myeloid precursor, CD34-positive") -AnnotationAssertion(Annotation( "ISBN:0878932437") Annotation( ) "CFU-GEMM") -AnnotationAssertion(Annotation( "ISBN:0878932437") Annotation( ) "CFU-S") -AnnotationAssertion(Annotation( "ISBN:0878932437") Annotation( ) "CMP") -AnnotationAssertion(Annotation( "ISBN:0878932437") "colony forming unit granulocyte, erythrocyte, macrophage, and megakaryocyte") -AnnotationAssertion(Annotation( "ISBN:0878932437") "multipotential myeloid stem cell") -AnnotationAssertion(Annotation( "ISBN:0878932437") "myeloid stem cell") -AnnotationAssertion(Annotation( "ISBN:0878932437") "pluripotent stem cell (bone marrow)") -AnnotationAssertion(rdfs:comment "CMP are reportedly CD16-positive, CD32-positive, CD38-positive, CD45RA-negative, CD110-negative, CD117-positive, CD123-positive, and SCA1-negative.") -AnnotationAssertion(rdfs:label "common myeloid progenitor, CD34-positive") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (hematopoietic oligopotent progenitor cell, lineage-negative) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:19022770") "A hematopoietic oligopotent progenitor cell that has the ability to differentiate into limited cell types but lacks lineage cell markers and self renewal capabilities. Cell lacks hematopoeitic lineage markers.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-01-06T03:43:27Z") -AnnotationAssertion(rdfs:label "hematopoietic oligopotent progenitor cell, lineage-negative") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (erythroid progenitor cell, mammalian) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0721601464") "A progenitor cell committed to the erythroid lineage. This cell is ter119-positive but lacks expression of other hematopoietic lineage markers (lin-negative).") -AnnotationAssertion( "BTO:0004911") -AnnotationAssertion(Annotation( ) "BFU-E") -AnnotationAssertion(Annotation( ) "CFU-E") -AnnotationAssertion( "blast forming unit erythroid") -AnnotationAssertion( "burst forming unit erythroid") -AnnotationAssertion( "colony forming unit erythroid") -AnnotationAssertion( "erythroid stem cell") -AnnotationAssertion(rdfs:label "erythroid progenitor cell, mammalian") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (lymphocyte of B lineage, CD19-positive) - -AnnotationAssertion(Annotation( "GOC:add") "A lymphocyte of B lineage that is CD19-positive.") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "Types of B lineage lymphocytes include B cells and antibody secreting cells (plasmablasts and plasma cells). Lymphocytes of B cell lineage can be distinguished from those of T cell lineage by their lack of CD3e (as part of the T cell receptor complex).") -AnnotationAssertion(rdfs:label "lymphocyte of B lineage, CD19-positive") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ) - # Class: (B cell, CD19-positive) AnnotationAssertion(Annotation( "GOC:add") "A B cell that is CD19-positive.") @@ -35443,86 +18200,8 @@ AnnotationAssertion( "CD19+ B cell") AnnotationAssertion( "CD19-positive B cell") AnnotationAssertion(rdfs:label "B cell, CD19-positive") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (Kit-positive erythroid progenitor cell) - -AnnotationAssertion(Annotation( "GOC:ak") Annotation( "GOC:tfm") Annotation( "PMID:19805084") Annotation( "http://www.immgen.org/index_content.html") "An erythroid progenitor cell is Kit-positive, Ly6A-negative, CD41-negative, CD127-negative, and CD123-negative. This cell type is also described as being lin-negative, Kit-positive, CD150-negative, CD41-negative, CD105-positive, and FcgR-negative.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-04-26T10:14:16Z") -AnnotationAssertion( "c- Kit-positive erythroid progenitor cell") -AnnotationAssertion(rdfs:comment "Markers found on mouse cells.") -AnnotationAssertion(rdfs:label "Kit-positive erythroid progenitor cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (CD34-positive, CD38-positive granulocyte monocyte progenitor) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:12615892") Annotation( "PMID:19022770") "A granulocyte monocyte progenitor is CD34-positive, CD38-positive, IL-3receptor-alpha-positive and is CD45RA-negative.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-01-13T03:19:22Z") -AnnotationAssertion(rdfs:comment "Markers are for human cells. According to different research groups, CD45RA is present or absent on this cell population.") -AnnotationAssertion(rdfs:label "CD34-positive, CD38-positive granulocyte monocyte progenitor") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (Kit-positive granulocyte monocyte progenitor) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:12615892") Annotation( "PMID:16322423") Annotation( "PMID:19022770") Annotation( "PMID:19273628") Annotation( "http://www.immgen.org/index_content.html") "A granulocyte monocyte progenitor that is Kit-positive, CD34-positive, Fc-gamma receptor II/II-positive, and is Sca-1-negative, Il7ra-negative, Cxc3r1-negative, and CD90-negative.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-01-13T03:19:28Z") -AnnotationAssertion(rdfs:comment "Markers are found on mouse cells.") -AnnotationAssertion(rdfs:label "Kit-positive granulocyte monocyte progenitor") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (CD34-positive, GlyA-negative erythroid progenitor cell) - -AnnotationAssertion(Annotation( "GOC:ak") Annotation( "GOC:tfm") Annotation( "PMID:19621348") "An erythroid progenitor cell that is CD34-positive and is GlyA-negative.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-04-26T10:14:30Z") -AnnotationAssertion( "FMA:83517") -AnnotationAssertion(rdfs:comment "Cell markers associated with human cells.") -AnnotationAssertion(rdfs:label "CD34-positive, GlyA-negative erythroid progenitor cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (CD34-negative, GlyA-negative proerythroblast) - -AnnotationAssertion(Annotation( "GOC:ak") Annotation( "GOC:tfm") Annotation( "PMID:19621348") "A proerythoblast that is CD34-negative and GlyA-negative.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-04-26T10:31:50Z") -AnnotationAssertion(rdfs:comment "Cell surface markers are associated with human cells.") -AnnotationAssertion(rdfs:label "CD34-negative, GlyA-negative proerythroblast") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (CD34-positive, CD38-positive megakaryocyte erythroid progenitor cell) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:12615892") Annotation( "PMID:190227700") "A megakaryocyte erythroid progenitor cell is CD34-positive, CD38-positive and is IL3-receptor alpha-negative and CD45RA-negative.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-01-13T03:43:10Z") -AnnotationAssertion(rdfs:comment "Markers are associated with human cell type.") -AnnotationAssertion(rdfs:label "CD34-positive, CD38-positive megakaryocyte erythroid progenitor cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (Kit-positive, CD34-negative megakaryocyte erythroid progenitor cell) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:12615892") Annotation( "PMID:19022770") Annotation( "http://www.immgen.org/index_content.html") "A megakaryocyte erythroid progenitor cell that is Kit-positive and is Sca1-negative, CD34-negative, CD90-negative, IL7r-alpha-negative and Fcgr II/III-low.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-01-13T03:43:12Z") -AnnotationAssertion(rdfs:comment "Markers are associated with mouse cells.") -AnnotationAssertion(rdfs:label "Kit-positive, CD34-negative megakaryocyte erythroid progenitor cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - # Class: (macrophage dendritic cell progenitor) AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:19273628") "A progenitor cell that can give rise to plasmacytoid and myeloid dendritic cells, and to monocytes and macrophages.") @@ -35530,143 +18209,9 @@ AnnotationAssertion( "2010-01-19T02:51:58Z") AnnotationAssertion( "MDP") AnnotationAssertion(rdfs:label "macrophage dendritic cell progenitor") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (Kit-positive macrophage dendritic cell progenitor) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:19273628") "A progenitor cell that can give rise to plasmacytoid and myeloid dendritic cells, and to monocytes and macrophages. Marker for this cell is Kit-high, CD115-positive, CD135-positive, Cx3cr1-positive, and is Il7ra-negative.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-01-26T02:43:40Z") -AnnotationAssertion( "murine MDP") -AnnotationAssertion(rdfs:comment "Markers are associated with mouse cells.") -AnnotationAssertion(rdfs:label "Kit-positive macrophage dendritic cell progenitor") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (Kit-low proerythroblast) - -AnnotationAssertion(Annotation( "GOC:ak") Annotation( "GOC:tfm") Annotation( "PMID:19805084") "A proerythoblast that is Kit-low, Lyg76-positive, and CD71-positive.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-04-26T10:31:56Z") -AnnotationAssertion(rdfs:comment "Markers are associated with mouse cells.") -AnnotationAssertion(rdfs:label "Kit-low proerythroblast") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (GlyA-positive basophilic erythroblast) - -AnnotationAssertion(Annotation( "GOC:ak") Annotation( "GOC:tfm") Annotation( "PMID:1638021") "A basophilic erythroblast that is GlyA-positive.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-04-26T10:41:15Z") -AnnotationAssertion(rdfs:comment "Markers are associated with human cells.") -AnnotationAssertion(rdfs:label "GlyA-positive basophilic erythroblast") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (Kit-negative, Ly-76 high basophilic erythroblast) - -AnnotationAssertion(Annotation( "GOC:ak") Annotation( "GOC:tfm") Annotation( "PMID:19805084") "A basophilic erythroblast that is Lyg 76-high and is Kit-negative.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-04-26T10:41:22Z") -AnnotationAssertion(rdfs:comment "Cell surface markers are associated with mouse cells.") -AnnotationAssertion(rdfs:label "Kit-negative, Ly-76 high basophilic erythroblast") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (Kit-negative, Ly-76 high polychromatophilic erythroblast) - -AnnotationAssertion(Annotation( "GOC:ak") Annotation( "GOC:tfm") Annotation( "PMID:19805084") "A polychromatophilic erythroblast that is Lyg 76-high and is Kit-negative.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-04-26T10:53:11Z") -AnnotationAssertion( "late basophilic and polychromatophilic erythroblast") -AnnotationAssertion(rdfs:label "Kit-negative, Ly-76 high polychromatophilic erythroblast") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (CD71-low, GlyA-positive polychromatic erythroblast) - -AnnotationAssertion(Annotation( "GOC:ak") Annotation( "GOC:tfm") Annotation( "PMID:1638021") "A polychromatiic erythroblast that is Gly-A-positive and CD71-low.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-04-26T10:53:16Z") -AnnotationAssertion(rdfs:comment "Cell surface markers are associated with human cells.") -AnnotationAssertion(rdfs:label "CD71-low, GlyA-positive polychromatic erythroblast") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (Kit-negative, Ly-76 high orthochromatophilic erythroblasts) - -AnnotationAssertion(Annotation( "GOC:ak") Annotation( "GOC:tfm") Annotation( "PMID:19805084") "An orthochromatophilic erythroblast that is ter119-high, CD71-low, and Kit-negative.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-04-26T11:04:15Z") -AnnotationAssertion(rdfs:comment "Cell surface markers associated with mouse cells.") -AnnotationAssertion(rdfs:label "Kit-negative, Ly-76 high orthochromatophilic erythroblasts") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (CD71-negative, GlyA-positive orthochromatic erythroblast) - -AnnotationAssertion(Annotation( "GOC:ak") Annotation( "GOC:tfm") Annotation( "PMID:1638021") "An erythroblast that is GlyA-positive and CD71-negative.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-04-26T11:04:21Z") -AnnotationAssertion(rdfs:comment "Markers associated with human cells.") -AnnotationAssertion(rdfs:label "CD71-negative, GlyA-positive orthochromatic erythroblast") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (Ly-76 high reticulocyte) - -AnnotationAssertion(Annotation( "GOC:ak") Annotation( "GOC:tfm") Annotation( "PMID:18539294") "A reticulocyte that is Ly76-high and is Kit-negative.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-04-26T11:37:00Z") -AnnotationAssertion(rdfs:comment "Marker associated with mouse cells.") -AnnotationAssertion(rdfs:label "Ly-76 high reticulocyte") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (GlyA-positive reticulocytes) - -AnnotationAssertion(Annotation( "GOC:ak") Annotation( "GOC:tfm") Annotation( "PMID:1638021") "A reticulocyte that is GlyA-positive.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-04-26T11:48:25Z") -AnnotationAssertion(rdfs:comment "Markers is associated with human cells.") -AnnotationAssertion(rdfs:label "GlyA-positive reticulocytes") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (GlyA-positive erythrocyte) - -AnnotationAssertion(Annotation( "GOC:ak") Annotation( "GOC:tfm") Annotation( "PMID:20134094") "An enucleate erythrocyte that is GlyA-positive.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-04-26T11:51:22Z") -AnnotationAssertion(rdfs:comment "Marker is associated with human cell types.") -AnnotationAssertion(rdfs:label "GlyA-positive erythrocyte") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (Ly-76 high positive erythrocyte) - -AnnotationAssertion(Annotation( "GOC:ak") Annotation( "GOC:tfm") Annotation( "PMID:19805084") "An enucleate erythrocyte that is Lyg-76-high.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-04-26T11:51:27Z") -AnnotationAssertion(rdfs:comment "Marker is associated with mouse cell types.") -AnnotationAssertion(rdfs:label "Ly-76 high positive erythrocyte") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (hematopoietic lineage restricted progenitor cell) AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:19022770") "A hematopoietic progenitor cell that is capable of developing into only one lineage of hematopoietic cells.") @@ -35674,7 +18219,6 @@ AnnotationAssertion( "2010-01-06T03:43:20Z") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "hematopoietic lineage restricted progenitor cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) @@ -35688,166 +18232,10 @@ AnnotationAssertion( AnnotationAssertion( ) AnnotationAssertion(rdfs:comment "This cell type is intended to be compatible with any vertebrate hematopoietic oligopotent progenitor cell. For mammalian hematopoietic oligopotent progenitor cells known to be lineage-negative, please use the term 'hematopoietic oligopotent progenitor cell' (CL_0001060).") AnnotationAssertion(rdfs:label "hematopoietic oligopotent progenitor cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (short term hematopoietic stem cell) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:15572596") Annotation( "PMID:19022770") "A hematopoietic stem cell capable of rapid replenishment of myeloerythroid progenitors and limited self renewal capability. This cell is Kit-positive, Sca1-positive, CD34-positive, CD150-positive, and is Flt3-negative.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-01-08T09:19:25Z") -AnnotationAssertion( "ST stem cell") -AnnotationAssertion( "ST-HSC") -AnnotationAssertion(rdfs:comment "Markers are associated with mouse cells. These cells are also reportedly CD11b-low and CD90-low.") -AnnotationAssertion(rdfs:label "short term hematopoietic stem cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (long term hematopoietic stem cell) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:15572596") Annotation( "PMID:17582345") "A hematopoietic stem cell with long term self renewal capability. This cell is Kit-positive, Sca1-positive, CD150-positive, CD90-low, CD34-negative and Flt3-negative.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-01-08T09:19:28Z") -AnnotationAssertion( "LT stem cell") -AnnotationAssertion( "LT-HSC") -AnnotationAssertion(rdfs:comment "Markers are associated with mouse cells.") -AnnotationAssertion(rdfs:label "long term hematopoietic stem cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (Slamf1-negative multipotent progenitor cell) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:19022770") "A hematopoietic progenitor that has restricted self-renewal capability. Cell is Kit-positive, Ly6-positive, CD150-negative and Flt3-negative.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-01-08T11:16:33Z") -AnnotationAssertion(rdfs:comment "Markers are associated with mouse cells.") -AnnotationAssertion(rdfs:label "Slamf1-negative multipotent progenitor cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (Slamf1-positive multipotent progenitor cell) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:19022770") "A hematopoietic progenitor that has some limited self-renewal capability. Cells are lin-negative, Kit-positive, CD34-positive, and Slamf1-positive.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-01-08T11:16:35Z") -AnnotationAssertion( "KSL cell") -AnnotationAssertion(rdfs:comment "Markers are associated with mouse cells.") -AnnotationAssertion(rdfs:label "Slamf1-positive multipotent progenitor cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) -DisjointClasses( ) - -# Class: (CD34-positive, CD38-negative multipotent progenitor cell) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:18371405") Annotation( "PMID:19022770") "A hematopoietic multipotent progenitor cell that is CD34-positive, CD38-negative, CD45RA-negative, and CD90-negative.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-01-12T11:14:15Z") -AnnotationAssertion(rdfs:comment "Cell markers are associated with human hematopoietic multipotent progenitor cells.") -AnnotationAssertion(rdfs:label "CD34-positive, CD38-negative multipotent progenitor cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (fraction A pre-pro B cell) - -AnnotationAssertion(Annotation( "GOC:ak") Annotation( "GOC:tfm") Annotation( "PMID:12633665") Annotation( "PMID:17582343") Annotation( "http://www.immgen.org/index_content.html") "A pro-B cell that is CD45R/B220-positive, CD43-positive, HSA-low, BP-1-negative and Ly6c-negative. This cell type is also described as being lin-negative, AA4-positive, Kit-positive, IL7Ra-positive and CD45R-positive.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-04-28T10:50:07Z") -AnnotationAssertion( "fraction A") -AnnotationAssertion( "pre pro B cell") -AnnotationAssertion(rdfs:comment "Markers associated with mouse cells.") -AnnotationAssertion(rdfs:label "fraction A pre-pro B cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (fraction B precursor B cell) - -AnnotationAssertion(Annotation( "GOC:ak") Annotation( "GOC:tfm") Annotation( "PMID:18432934") "A precursor B cell that is CD45RA-positive, CD43-positive, CD24-positive and BP-1-negative.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-04-28T11:56:21Z") -AnnotationAssertion( "Fr. B") -AnnotationAssertion( "Fraction B") -AnnotationAssertion(rdfs:comment "Markers are commonly associated with mouse cells. These cells are also reportedly RAG1-positive and RAG2-positive.") -AnnotationAssertion(rdfs:label "fraction B precursor B cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (fraction C precursor B cell) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:17582343") "A precursor B cell that is CD45R-positive, CD43-positive, CD24-positive, and BP-positive. Intracellularly expression of surrogate light chain, Rag1 and Rag2, TdT, occurs while there is no expression of mu heavy chain.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-04-28T02:04:01Z") -AnnotationAssertion( "Fraction C") -AnnotationAssertion(rdfs:label "fraction C precursor B cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (fraction C' precursor B cell) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:17582343") "A pre-BCR-positive precursor B cell that is CD24-high, CD25-positive, CD43-positive, CD45R-positive and BP-positive.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-04-28T02:13:46Z") -AnnotationAssertion( "Fr. C'") -AnnotationAssertion( "Fraction C-prime") -AnnotationAssertion(rdfs:label "fraction C' precursor B cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (fraction D precursor B cell) - -AnnotationAssertion(Annotation( "GOC:ak") Annotation( "GOC:dsd") Annotation( "GOC:tfm") Annotation( "PMID:17582343") Annotation( "PMID:18432934") Annotation( "http://www.immgen.org/index_content.html") "A pre-B cell that is pre-BCR-negative, and the kappa- and lambda- light immunoglobulin light chain-negative, CD43-low, and is BP-1-positive, CD45R-positive and CD25-positive. This cell type is also described as being AA4-positive, IgM-negative, CD19-positive, CD43-low/negative, and HSA-positive.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-04-28T02:55:16Z") -AnnotationAssertion( "Fr. D") -AnnotationAssertion(Annotation( "GOC:tfm") "fraction D pre-B cell") -AnnotationAssertion(rdfs:comment "Fraction D precursor B cells are also reportedly CD24-positive and sIgD-negative.") -AnnotationAssertion(rdfs:label "fraction D precursor B cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (fraction E immature B cell) - -AnnotationAssertion(Annotation( "GOC:ak") Annotation( "GOC:dsd") Annotation( "GOC:tfm") Annotation( "PMID:17582343") Annotation( "PMID:18432934") "An immature B cell that is IgM-positive, CD45R-positive, CD43-low, CD25-negative, and CD127-negative. This cell type has also been described as being AA4-positive, IgM-positive, CD19-positive, CD43-low/negative, and HSA-positive.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-04-28T03:13:47Z") -AnnotationAssertion(rdfs:comment "Markers associated with mouse cells. These cells are also reportedly sIgD-negative.") -AnnotationAssertion(rdfs:label "fraction E immature B cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (fraction F mature B cell) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:17582343") "A mature B cell subset originally defined as having being CD45R-positive, IgM-positive, IgD-positive and CD43-negative. Subsequent research demonstrated being CD21-positive and CD23-negative and CD93 negative.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-04-30T03:01:48Z") -AnnotationAssertion(rdfs:label "fraction F mature B cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (CD8alpha-positive thymic conventional dendritic cell) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:19273629") Annotation( "http://www.immgen.org/index_content.html") "A conventional thymic dendritic cell that is CD8alpha-positive.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "2010-06-07T02:48:36Z") -AnnotationAssertion( "CD8alpha-alpha-positive thymic conventional dendritic cell") -AnnotationAssertion( "DC.8+.Th") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "CD8alpha-positive thymic conventional dendritic cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - # Class: (type I pneumocyte) AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:20054144") Annotation( "http://www.copewithcytokines.de") "A type I pneumocyte is a flattened, branched pneumocyte that covers more than 98% of the alveolar surface. This large cell has thin (50-100 nm) cytoplasmic extensions to form the air-blood barrier essential for normal gas exchange.") @@ -35870,7 +18258,6 @@ AnnotationAssertion( "type I alveolar epithelial cells") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "type I pneumocyte") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (type II pneumocyte) @@ -35896,7 +18283,6 @@ AnnotationAssertion( "lung type II cell") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "type II pneumocyte") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf( ObjectSomeValuesFrom( )) # Class: (pancreatic acinar cell) @@ -35911,7 +18297,6 @@ AnnotationAssertion( "acinar cell of pancreas") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "pancreatic acinar cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) SubClassOf(Annotation( "true") ) SubClassOf( ObjectSomeValuesFrom( )) @@ -35923,7 +18308,6 @@ AnnotationAssertion( "2010-09-10T10:48:54Z") AnnotationAssertion( "FMA:62939") AnnotationAssertion(rdfs:label "type A enteroendocrine cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (Purkinje myocyte) @@ -35940,30 +18324,6 @@ AnnotationAssertion( "Purkinje myocyte") SubClassOf( ) -# Class: (type II vestibular sensory cell) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "ISBN:0517223651") "Mostly cylindrical, resemble Type 1 in their contents and the presence of a kinocilium and stereocilium apically; much greater variation in size, some almost span the entire thickness of the sensory epithelium, while others are smaller than Type 1; receive multiple efferent nerve boutons around their bases as well as afferent endings, which are small expansions rather than chalices.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-06-29T09:58:13Z") -AnnotationAssertion( "FMA:67909") -AnnotationAssertion( "type 2 vestibular hair cell") -AnnotationAssertion( "type 2 vestibular sensory cell") -AnnotationAssertion( "type II hair cell") -AnnotationAssertion(rdfs:label "type II vestibular sensory cell") -SubClassOf( ) - -# Class: (type I vestibular sensory cell) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "ISBN:0517223651") "Bottle-shaped with narrow neck; broad, rounded basal portion where nucleus is located; stereocilia and a single kinocilium is present apically; receive nerve bouton at their base from an afferent cup-shaped (chalice or calyx) nerve ending.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-06-29T09:58:19Z") -AnnotationAssertion( "FMA:62352") -AnnotationAssertion( "type 1 vestibular hair cell") -AnnotationAssertion( "type 1 vestibular sensory cell") -AnnotationAssertion( "type I hair cell") -AnnotationAssertion(rdfs:label "type I vestibular sensory cell") -SubClassOf( ) - # Class: (nodal myocyte) AnnotationAssertion(Annotation( "FMA:67101") Annotation( "GOC:tfm") "A specialized cardiac myocyte in the sinoatrial and atrioventricular nodes. The cell is slender and fusiform confined to the nodal center, circumferentially arranged around the nodal artery.") @@ -35997,15 +18357,6 @@ AnnotationAssertion(rdfs:label "myoc SubClassOf( ) SubClassOf( ) -# Class: (brush cell of trachebronchial tree) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "ISBN:0517223651") Annotation( "PMID:15817800") "Infrequent type of columnar epithelial cell. This cell is characterized by the presence of a tuft of blunt, squat microvilli (approximately 120-140/cell) on the cell surface. The microvilli contain filaments that stretch into the underlying cytoplasm. They have a distinctive pear shape with a wide base and a narrow microvillous apex. Function not known.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-06-29T03:22:46Z") -AnnotationAssertion( "pulmonary brush cell") -AnnotationAssertion(rdfs:label "brush cell of trachebronchial tree") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (endo-epithelial cell) AnnotationAssertion(Annotation( "FMA:69075") Annotation( "GOC:tfm") "An epithelial cell derived from endoderm.") @@ -36014,7 +18365,6 @@ AnnotationAssertion( AnnotationAssertion( "FMA:69075") AnnotationAssertion(rdfs:label "endo-epithelial cell") SubClassOf( ) -SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) # Class: (ecto-epithelial cell) @@ -36024,8 +18374,6 @@ AnnotationAssertion( "2010-06-29T03:38:22Z") AnnotationAssertion( "FMA:69074") AnnotationAssertion(rdfs:label "ecto-epithelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) # Class: (meso-epithelial cell) @@ -36035,35 +18383,6 @@ AnnotationAssertion( AnnotationAssertion( "FMA:69076") AnnotationAssertion( "epithelial mesenchymal cell") AnnotationAssertion(rdfs:label "meso-epithelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (pancreatic ductal cell) - -AnnotationAssertion(Annotation( "FMA:63099") Annotation( "GOC:tfm") Annotation( "PMID:14740223") "Epithelial cell found in the ducts of the pancreas. This cell type contributes to the high luminal pH.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "2010-06-30T08:49:43Z") -AnnotationAssertion( "FMA:63099") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "pancreatic ductal cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf(Annotation( "true") ) - -# Class: (pancreatic centro-acinar cell) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:12142741") Annotation( "PMID:20018761") Annotation( "PMID:8185160") "A cubodial epithelial cell that is continuous with the lining of intercalated ducts that drain the acinus. This cell type secretes a high pH solution to aid in activation of zymogens, and can differentiate into endocrine and exocrine pancreatic cell types.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "2010-06-30T08:49:52Z") -AnnotationAssertion( "FMA:62455") -AnnotationAssertion( "centroacinar cell of Langerhans") -AnnotationAssertion( "pancreatic centroacinar cell") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "pancreatic centro-acinar cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) # Class: (type II cell of carotid body) @@ -36086,7 +18405,6 @@ AnnotationAssertion( "adrenal secreting cell of the adrenal medulla") AnnotationAssertion( "epiniphrine secreting cell of the adrenal medulla") AnnotationAssertion(rdfs:label "type II cell of adrenal medulla") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) # Class: (type I cell of adrenal medulla) @@ -36097,7 +18415,6 @@ AnnotationAssertion( AnnotationAssertion( "FMA:69321") AnnotationAssertion( "noradrenergic chromaffin cell") AnnotationAssertion(rdfs:label "type I cell of adrenal medulla") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) # Class: (specialized cardiac myocyte) @@ -36109,34 +18426,6 @@ AnnotationAssertion( "specialized cardiac myocyte") SubClassOf( ) -# Class: (nongranular leukocyte) - -AnnotationAssertion(Annotation( "GOC:tfm") "A leukocyte that lacks granules.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-07-22T11:30:33Z") -AnnotationAssertion( "FMA:62855") -AnnotationAssertion( "agranular leukocyte") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "nongranular leukocyte") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (interstitial cell of Cajal) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:16460275") Annotation( "PMID:19520112") "This is a cell found in the gastrointestinal tract of mammals and serves as a pacemaker that triggers gut contraction. ICCs mediate inputs from the enteric nervous system to smooth muscle cells and are thought to be the cells from which gastrointestinal stromal tumors (GISTs) arise.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "2010-07-22T03:26:00Z") -AnnotationAssertion( "BTO:0003914") -AnnotationAssertion( "FMA:86573") -AnnotationAssertion( "ICC") -AnnotationAssertion(Annotation( "GOC:pr") "intestinal pacemaker cell") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "Some argue this cell type is of mesenchymal origin.") -AnnotationAssertion(rdfs:label "interstitial cell of Cajal") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - # Class: (bone marrow cell) AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "ISBN:0618947256") "A cell found in the bone marrow. This can include fibroblasts, macrophages, adipocytes, osteoblasts, osteoclasts, endothelial cells and hematopoietic cells.") @@ -36147,7 +18436,6 @@ AnnotationAssertion( "MESH:D001854") AnnotationAssertion(rdfs:comment "MH consider whether bone marrow cells are bone cells in the structural sense vs. being part of bone organ sense.") AnnotationAssertion(rdfs:label "bone marrow cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) # Class: (hilus cell of ovary) @@ -36163,16 +18451,6 @@ AnnotationAssertion(rdfs:label "hilu SubClassOf( ) SubClassOf( ) -# Class: (internodal tract myocyte) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "ISBN:0781729300") "A specialised myocyte that lies between the sinoatrial node and the atrioventricular node and is involved in the conduction of electrical signals.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-08-23T11:24:11Z") -AnnotationAssertion( "FMA:223275") -AnnotationAssertion(rdfs:label "internodal tract myocyte") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - # Class: (cortical cell of adrenal gland) AnnotationAssertion(Annotation( "GOC:tfm") "A cell of the adrenal cortex. Cell types include those that synthesize and secrete chemical derivatives (steroids) of cholesterol.") @@ -36182,267 +18460,10 @@ AnnotationAssertion( "adrenal cortex cell") AnnotationAssertion( "adrenocortical cell") AnnotationAssertion(rdfs:label "cortical cell of adrenal gland") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf(Annotation( "true") ) -# Class: (type I cell of adrenal cortex) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "ISBN:0517223651") "A small, polyhedral, cell found in rounded groups or curved columns with deeply staining nuclei, scanty basophilic cytoplasm and a few lipid droplets. This cell in the zona glomerulosa produces mineralocorticoids.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-08-24T01:42:02Z") -AnnotationAssertion( "FMA:69273") -AnnotationAssertion( "epithelial cell of zona glomerulosa of adrenal gland") -AnnotationAssertion(rdfs:label "type I cell of adrenal cortex") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf(Annotation( "true") ) - -# Class: (CD38-positive naive B cell) - -AnnotationAssertion(Annotation( "GOC:dsd") Annotation( "GOC:rhs") Annotation( "GOC:tfm") Annotation( "PMID:20123131") "A CD38-positive naive B cell is a mature B cell that has the phenotype CD38-positive, surface IgD-positive, surface IgM-positive, and CD27-negative, and that has not yet been activated by antigen in the periphery.") -AnnotationAssertion( "CD38+ naive B cell") -AnnotationAssertion( "CD38+ naive B lymphocyte") -AnnotationAssertion( "CD38+ naive B-cell") -AnnotationAssertion( "CD38+ naive B-lymphocyte") -AnnotationAssertion( "CD38-positive naive B lymphocyte") -AnnotationAssertion( "CD38-positive naive B-cell") -AnnotationAssertion( "CD38-positive naive B-lymphocyte") -AnnotationAssertion(rdfs:label "CD38-positive naive B cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (CD38-negative naive B cell) - -AnnotationAssertion(Annotation( "GOC:dsd") Annotation( "GOC:rhs") Annotation( "GOC:tfm") Annotation( "PMID:20123131") "A CD38-negative naive B cell is a mature B cell that has the phenotype CD38-negative, surface IgD-positive, surface IgM-positive, and CD27-negative, that has not yet been activated by antigen in the periphery.") -AnnotationAssertion( "CD38- naive B cell") -AnnotationAssertion( "CD38- naive B lymphocyte") -AnnotationAssertion( "CD38- naive B-cell") -AnnotationAssertion( "CD38- naive B-lymphocyte") -AnnotationAssertion( "CD38-negative naive B lymphocyte") -AnnotationAssertion( "CD38-negative naive B-cell") -AnnotationAssertion( "CD38-negative naive B-lymphocyte") -AnnotationAssertion(rdfs:label "CD38-negative naive B cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (IgG-positive double negative memory B cell) - -AnnotationAssertion(Annotation( "GOC:dsd") Annotation( "GOC:rhs") Annotation( "GOC:tfm") Annotation( "PMID:20123131") "An IgG-positive double negative memory B cell is a double negative memory B cell with the phenotype IgG-positive, IgD-negative, and CD27-negative.") -AnnotationAssertion( "IgG+ dn memory B cell") -AnnotationAssertion( "IgG+ dn memory B lymphocyte") -AnnotationAssertion( "IgG+ dn memory B-cell") -AnnotationAssertion( "IgG+ dn memory B-lymphocyte") -AnnotationAssertion( "IgG+ double negative memory B cell") -AnnotationAssertion( "IgG+ double negative memory B lymphocyte") -AnnotationAssertion( "IgG+ double negative memory B-cell") -AnnotationAssertion( "IgG+ double negative memory B-lymphocyte") -AnnotationAssertion( "IgG-positive dn memory B cell") -AnnotationAssertion( "IgG-positive dn memory B lymphocyte") -AnnotationAssertion( "IgG-positive dn memory B-cell") -AnnotationAssertion( "IgG-positive dn memory B-lymphocyte") -AnnotationAssertion( "IgG-positive double negative memory B lymphocyte") -AnnotationAssertion( "IgG-positive double negative memory B-cell") -AnnotationAssertion( "IgG-positive double negative memory B-lymphocyte") -AnnotationAssertion(rdfs:label "IgG-positive double negative memory B cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (IgG-negative double negative memory B cell) - -AnnotationAssertion(Annotation( "GOC:dsd") Annotation( "GOC:rhs") Annotation( "GOC:tfm") Annotation( "PMID:20123131") "An IgG-negative double negative memory B cell is a double negative memory B cell with the phenotype IgG-negative, IgD-negative, and CD27-negative.") -AnnotationAssertion( "IgG- dn memory B cell") -AnnotationAssertion( "IgG- dn memory B lymphocyte") -AnnotationAssertion( "IgG- dn memory B-cell") -AnnotationAssertion( "IgG- dn memory B-lymphocyte") -AnnotationAssertion( "IgG- double negative memory B cell") -AnnotationAssertion( "IgG- double negative memory B lymphocyte") -AnnotationAssertion( "IgG- double negative memory B-cell") -AnnotationAssertion( "IgG- double negative memory B-lymphocyte") -AnnotationAssertion( "IgG-negative dn memory B cell") -AnnotationAssertion( "IgG-negative dn memory B lymphocyte") -AnnotationAssertion( "IgG-negative dn memory B-cell") -AnnotationAssertion( "IgG-negative dn memory B-lymphocyte") -AnnotationAssertion( "IgG-negative double negative memory B lymphocyte") -AnnotationAssertion( "IgG-negative double negative memory B-cell") -AnnotationAssertion( "IgG-negative double negative memory B-lymphocyte") -AnnotationAssertion(rdfs:label "IgG-negative double negative memory B cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (CD38-positive IgG memory B cell) - -AnnotationAssertion(Annotation( "GOC:dsd") Annotation( "GOC:rhs") Annotation( "GOC:tfm") Annotation( "PMID:20123131") "A CD38-positive IgG memory B cell is a class switched memory B cell that expresses IgG on the cell surface with the phenotype CD38-positive and IgG-positive.") -AnnotationAssertion( "CD38+ IgG memory B cell") -AnnotationAssertion( "CD38+ IgG memory B lymphocyte") -AnnotationAssertion( "CD38+ IgG memory B-cell") -AnnotationAssertion( "CD38+ IgG memory B-lymphocyte") -AnnotationAssertion( "CD38-positive IgG memory B lymphocyte") -AnnotationAssertion( "CD38-positive IgG memory B-cell") -AnnotationAssertion( "CD38-positive IgG memory B-lymphocyte") -AnnotationAssertion(rdfs:label "CD38-positive IgG memory B cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (IgD-positive CD38-positive IgG memory B cell) - -AnnotationAssertion(Annotation( "GOC:dsd") Annotation( "GOC:rhs") Annotation( "GOC:tfm") Annotation( "PMID:20123131") "An IgD-positive CD38-positive IgG memory B cell is a CD38-positive IgG-positive class switched memory B cell that has class switched and expresses IgD on the cell surface with the phenotype IgD-positive, CD38-positive, and IgG-positive.") -AnnotationAssertion(rdfs:label "IgD-positive CD38-positive IgG memory B cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (IgD-negative CD38-positive IgG memory B cell) - -AnnotationAssertion(Annotation( "GOC:dsd") Annotation( "GOC:rhs") Annotation( "GOC:tfm") Annotation( "PMID:20123131") "An IgD-negative CD38-positive IgG memory B cell is a CD38-positive IgG-positive that has class switched and lacks expression of IgD on the cell surface with the phenotype IgD-negative, CD38-positive, and IgG-positive.") -AnnotationAssertion(rdfs:label "IgD-negative CD38-positive IgG memory B cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (CD38-negative IgG memory B cell) - -AnnotationAssertion(Annotation( "GOC:dsd") Annotation( "GOC:rhs") Annotation( "GOC:tfm") Annotation( "PMID:20123131") "A CD38-negative IgG memory B cell is a IgG-positive class switched memory B cell that has class switched and expresses IgG on the cell surface with the phenotype CD38-negative, IgD-negative, and IgG-positive.") -AnnotationAssertion(rdfs:label "CD38-negative IgG memory B cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (B220-positive CD38-positive naive B cell) - -AnnotationAssertion(Annotation( "GOC:dsd") Annotation( "GOC:rhs") Annotation( "GOC:tfm") Annotation( "PMID:20123131") "A B220-positive CD38-positive naive B cell is a CD38-positive naive B cell that has the phenotype B220-positive, CD38-positive, surface IgD-positive, surface IgM-positive, and CD27-negative, and that has not yet been activated by antigen in the periphery.") -AnnotationAssertion( "B220+CD38+ naive B cell") -AnnotationAssertion( "B220+CD38+ naive B lymphocyte") -AnnotationAssertion( "B220+CD38+ naive B-cell") -AnnotationAssertion( "B220+CD38+ naive B-lymphocyte") -AnnotationAssertion( "B220-positive CD38-positive naive B lymphocyte") -AnnotationAssertion( "B220-positive CD38-positive naive B-cell") -AnnotationAssertion( "B220-positive CD38-positive naive B-lymphocyte") -AnnotationAssertion( "CD38+B220+ naive B cell") -AnnotationAssertion( "CD38+B220+ naive B lymphocyte") -AnnotationAssertion( "CD38+B220+ naive B-cell") -AnnotationAssertion( "CD38+B220+ naive B-lymphocyte") -AnnotationAssertion(rdfs:label "B220-positive CD38-positive naive B cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (B220-low CD38-positive naive B cell) - -AnnotationAssertion(Annotation( "GOC:dsd") Annotation( "GOC:rhs") Annotation( "GOC:tfm") Annotation( "PMID:20123131") "A B220-low CD38-positive naive B cell is a CD38-positive naive B cell that has the phenotype B220-low, CD38-positive, surface IgD-positive, surface IgM-positive, and CD27-negative, that has not yet been activated by antigen in the periphery.") -AnnotationAssertion(rdfs:label "B220-low CD38-positive naive B cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (CD38-negative unswitched memory B cell) - -AnnotationAssertion(Annotation( "GOC:dsd") Annotation( "GOC:rhs") Annotation( "GOC:tfm") Annotation( "PMID:20123131") "An CD38-negative unswitched memory B cell is an unswitched memory B cell that has the phenotype CD38-negative, IgD-positive, CD138-negative, and IgG-negative.") -AnnotationAssertion( "CD38- unswitched memory B cell") -AnnotationAssertion( "CD38- unswitched memory B lymphocyte") -AnnotationAssertion( "CD38- unswitched memory B-cell") -AnnotationAssertion( "CD38- unswitched memory B-lymphocyte") -AnnotationAssertion( "CD38-negative unswitched memory B lymphocyte") -AnnotationAssertion( "CD38-negative unswitched memory B-cell") -AnnotationAssertion( "CD38-negative unswitched memory B-lymphocyte") -AnnotationAssertion(rdfs:label "CD38-negative unswitched memory B cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (B220-positive CD38-negative unswitched memory B cell) - -AnnotationAssertion(Annotation( "GOC:dsd") Annotation( "GOC:rhs") Annotation( "GOC:tfm") Annotation( "PMID:20123131") "A B220-positive CD38-negative unswitched memory B cell is a CD38-negative unswitched memory B cell that has the phenotype B220-positive, CD38-negative, IgD-positive, CD138-negative, and IgG-negative.") -AnnotationAssertion(rdfs:label "B220-positive CD38-negative unswitched memory B cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (B220-low CD38-negative unswitched memory B cell) - -AnnotationAssertion(Annotation( "GOC:dsd") Annotation( "GOC:rhs") Annotation( "GOC:tfm") Annotation( "PMID:20123131") "A B220-low CD38-negative unswitched memory B cell is a CD38-negative unswitched memory B cell that has the phenotype B220-low, CD38-negative, IgD-positive, CD138-negative, and IgG-negative.") -AnnotationAssertion(rdfs:label "B220-low CD38-negative unswitched memory B cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (CD38-positive unswitched memory B cell) - -AnnotationAssertion(Annotation( "GOC:dsd") Annotation( "GOC:rhs") Annotation( "GOC:tfm") Annotation( "PMID:20123131") "A CD38-positive unswitched memory B cell is an unswitched memory B cell that has the phenotype CD38-positive, IgD-positive, CD138-negative, and IgG-negative.") -AnnotationAssertion( "CD38+ unswitched memory B cell") -AnnotationAssertion( "CD38+ unswitched memory B lymphocyte") -AnnotationAssertion( "CD38+ unswitched memory B-cell") -AnnotationAssertion( "CD38+ unswitched memory B-lymphocyte") -AnnotationAssertion( "CD38-positive unswitched memory B lymphocyte") -AnnotationAssertion( "CD38-positive unswitched memory B-cell") -AnnotationAssertion( "CD38-positive unswitched memory B-lymphocyte") -AnnotationAssertion(rdfs:label "CD38-positive unswitched memory B cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (B220-positive CD38-positive unswitched memory B cell) - -AnnotationAssertion(Annotation( "GOC:dsd") Annotation( "GOC:rhs") Annotation( "GOC:tfm") Annotation( "PMID:20123131") "A B220-positive CD38-positive unswitched memory B cell is a CD38-positive unswitched memory B cell that has the phenotype B220-positive, CD38-positive, IgD-positive, CD138-negative, and IgG-negative.") -AnnotationAssertion(rdfs:label "B220-positive CD38-positive unswitched memory B cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (B220-low CD38-positive unswitched memory B cell) - -AnnotationAssertion(Annotation( "GOC:dsd") Annotation( "GOC:rhs") Annotation( "GOC:tfm") Annotation( "PMID:20123131") "A B220-low CD38-positive unswitched memory B cell is a CD38-positive unswitched memory B cell that has the phenotype B220-low, CD38-positive, IgD-positive, CD138-negative, and IgG-negative.") -AnnotationAssertion(rdfs:label "B220-low CD38-positive unswitched memory B cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (IgG-negative class switched memory B cell) - -AnnotationAssertion(Annotation( "GOC:dsd") Annotation( "GOC:rhs") Annotation( "GOC:tfm") Annotation( "PMID:20123131") "A class switched memory B cell that lacks IgG on the cell surface.") -AnnotationAssertion( "IgG- class switched memory B cell") -AnnotationAssertion( "IgG- class switched memory B lymphocyte") -AnnotationAssertion( "IgG- class switched memory B-cell") -AnnotationAssertion( "IgG- class switched memory B-lymphocyte") -AnnotationAssertion( "IgG-negative class switched memory B lymphocyte") -AnnotationAssertion( "IgG-negative class switched memory B-cell") -AnnotationAssertion( "IgG-negative class switched memory B-lymphocyte") -AnnotationAssertion(rdfs:label "IgG-negative class switched memory B cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (CD38-negative IgG-negative class switched memory B cell) - -AnnotationAssertion(Annotation( "GOC:dsd") Annotation( "GOC:rhs") Annotation( "GOC:tfm") Annotation( "PMID:20123131") "A CD38-negative IgG-negative memory B cell is a IgG-negative class switched memory B cell that lacks IgG on the cell surface with the phenotype CD38-negative and IgG-negative.") -AnnotationAssertion(rdfs:label "CD38-negative IgG-negative class switched memory B cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (CD38-positive IgG-negative class switched memory B cell) - -AnnotationAssertion(Annotation( "GOC:dsd") Annotation( "GOC:rhs") Annotation( "GOC:tfm") Annotation( "PMID:20123131") "A CD38-positive IgG-negative memory B cell is an IgG-negative class switched memory B cell that lacks IgG on the cell surface with the phenotype CD38-positive and IgG-negative.") -AnnotationAssertion(rdfs:label "CD38-positive IgG-negative class switched memory B cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (CD24-positive CD38-negative IgG-negative class switched memory B cell) - -AnnotationAssertion(Annotation( "GOC:dsd") Annotation( "GOC:rhs") Annotation( "GOC:tfm") Annotation( "PMID:20123131") "An CD24-positive CD38-negative IgG-negative memory B cell is a CD38-negative IgG-negative class switched memory B cell that lacks IgG on the cell surface with the phenotype CD24-positive, CD38-negative, and IgG-negative.") -AnnotationAssertion(rdfs:label "CD24-positive CD38-negative IgG-negative class switched memory B cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (CD24-negative CD38-negative IgG-negative class switched memory B cell) - -AnnotationAssertion(Annotation( "GOC:dsd") Annotation( "GOC:rhs") Annotation( "GOC:tfm") Annotation( "PMID:20123131") "A CD24-negative CD38-negative IgG-negative memory B cell is a CD38-negative IgG-negative class switched memory B cell that lacks IgG on the cell surface with the phenotype CD24-negative, CD38-negative, and IgG-negative.") -AnnotationAssertion(rdfs:label "CD24-negative CD38-negative IgG-negative class switched memory B cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (B220-positive CD38-positive IgG-negative class switched memory B cell) - -AnnotationAssertion(Annotation( "GOC:dsd") Annotation( "GOC:rhs") Annotation( "GOC:tfm") Annotation( "PMID:20123131") "A B220-positive CD38-positive IgG-negative memory B cell is a CD38-positive IgG-negative class switched memory B cell that lacks IgG on the cell surface with the phenotype B220-positive, CD38-positive, and IgG-negative.") -AnnotationAssertion(rdfs:label "B220-positive CD38-positive IgG-negative class switched memory B cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (B220-low CD38-positive IgG-negative class switched memory B cell) - -AnnotationAssertion(Annotation( "GOC:dsd") Annotation( "GOC:rhs") Annotation( "GOC:tfm") Annotation( "PMID:20123131") "A B220-low CD38-positive IgG-negative memory B cell is a CD38-positive IgG-negative class switched memory B cell that lacks IgG on the cell surface with the phenotype B220-low, CD38-positive, and IgG-positive.") -AnnotationAssertion(rdfs:label "B220-low CD38-positive IgG-negative class switched memory B cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - # Class: (stromal cell of ovary) AnnotationAssertion(Annotation( "GOC:tfm") "A stomal cell of the ovary") @@ -36451,17 +18472,6 @@ AnnotationAssertion( AnnotationAssertion( "FMA:72299") AnnotationAssertion(Annotation( "GOC:cjm") "ovarian stromal cell") AnnotationAssertion(rdfs:label "stromal cell of ovary") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (stromal cell of ovarian medulla) - -AnnotationAssertion(Annotation( "GOC:tfm") "A stromal cell of the ovarian medulla.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-08-23T12:12:17Z") -AnnotationAssertion( "FMA:256171") -AnnotationAssertion(rdfs:label "stromal cell of ovarian medulla") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) # Class: (type II cell of adrenal cortex) @@ -36496,7 +18506,6 @@ AnnotationAssertion( "lymphatic endothelial cell") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "endothelial cell of lymphatic vessel") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) # Class: (endothelial cell of vascular tree) @@ -36513,34 +18522,6 @@ AnnotationAssertion(rdfs:comment "Th AnnotationAssertion(rdfs:label "endothelial cell of vascular tree") SubClassOf( ) -# Class: (acinar cell of sebaceous gland) - -AnnotationAssertion(Annotation( "GOC:tfm") "A sebum secreting cell of the skin that secretes sebum into the hair follicles.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-08-24T09:27:52Z") -AnnotationAssertion( "sebocyte") -AnnotationAssertion( "BTO:0004613") -AnnotationAssertion( "FMA:70953") -AnnotationAssertion(rdfs:label "acinar cell of sebaceous gland") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) -SubClassOf( ) - -# Class: (capillary endothelial cell) - -AnnotationAssertion(Annotation( "GOC:tfm") "An endothelial cell found in capillaries.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "2010-08-24T10:15:00Z") -AnnotationAssertion( "BTO:0004956") -AnnotationAssertion( "CALOHA:TS-0112") -AnnotationAssertion( "FMA:67756") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "capillary endothelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - # Class: (ciliated columnar cell of tracheobronchial tree) AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "ISBN:0517223651") "A ciliated columnar cell found in the trachea and bronchus. Vary from low to tall columnar; possesses up to 300 cilia at its surface, interspersed with long irregular microvilli with the cilia varying in length from about 6um in the trachea to about 4um in the terminal bronchioles; driving force of the ciliary current in the bronchial tree.") @@ -36563,17 +18544,6 @@ AnnotationAssertion( AnnotationAssertion( "CALOHA:TS-0195") AnnotationAssertion( "FMA:87170") AnnotationAssertion(rdfs:label "dental pulp cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (epithelial cell of uterus) - -AnnotationAssertion(Annotation( "GOC:tfm") "An epithelial cell of the uterus.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-08-24T10:45:54Z") -AnnotationAssertion( "FMA:256161") -AnnotationAssertion(rdfs:label "epithelial cell of uterus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) # Class: (corneocyte) @@ -36587,7 +18557,6 @@ AnnotationAssertion( "corneocyte") SubClassOf( ) SubClassOf( ) -SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) @@ -36619,7 +18588,6 @@ AnnotationAssertion( "2010-08-26T01:47:13Z") AnnotationAssertion( "FMA:67870") AnnotationAssertion(rdfs:label "olfactory epithelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) @@ -36631,20 +18599,8 @@ AnnotationAssertion( AnnotationAssertion( "horizontal basal cell") AnnotationAssertion( "FMA:62303") AnnotationAssertion(rdfs:label "basal cell of olfactory epithelium") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) -# Class: (keratinized cell of the oral mucosa) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:12014572") "A keratinized cell located in the hard palate or gingiva.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-08-26T02:51:30Z") -AnnotationAssertion(rdfs:label "keratinized cell of the oral mucosa") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (extraglomerular mesangial cell) AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "ISBN:0412046911") Annotation( "http:/www.copewithcytokines.de/cope.cgi?key=Lacis%20cells") "A cell that is a specialized type of pericyte providing structural support for the capillary loops of kidney. A flat, elongated cell with extensive fine cytoplasmic processes found outside the kidney glomerulus near the macula densa and bound laterally by afferent and efferent arterioles. Being phagocytic, this cell participates in the continuous turnover of the basal lamina by removing its outer portion containing residues of filtration, while the lamina is renewed on its inner surface by the endothelial cells.") @@ -36656,7 +18612,6 @@ AnnotationAssertion( "polar cushion cells") AnnotationAssertion( "lacis cell") AnnotationAssertion(rdfs:label "extraglomerular mesangial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf(Annotation( "true") ) SubClassOf(Annotation( "true") ) @@ -36673,18 +18628,6 @@ AnnotationAssertion(rdfs:label "foll SubClassOf( ) SubClassOf( ) -# Class: (folliculostellate cell of pars distalis of adenohypophysis) - -AnnotationAssertion(Annotation( "GOC:tfm") "A supporting cell of the anterior pituitary gland involved in trophic and catabolic processes; expresses a broad spectrum of cytokeratins indicative of their epithelial nature.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-08-25T03:10:10Z") -AnnotationAssertion( "FMA:83102") -AnnotationAssertion( "folliculostellate cell of pars anterior of adenohypophysis") -AnnotationAssertion(rdfs:label "folliculostellate cell of pars distalis of adenohypophysis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) - # Class: (epithelial cell of stomach) AnnotationAssertion(Annotation( "GOC:tfm") "An epithelial cell found in the lining of the stomach.") @@ -36692,31 +18635,8 @@ AnnotationAssertion( "2010-08-25T03:22:08Z") AnnotationAssertion( "FMA:62948") AnnotationAssertion(rdfs:label "epithelial cell of stomach") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) -# Class: (mucous cell of stomach) - -AnnotationAssertion(Annotation( "GOC:tfm") "A mucous cell in the epithelium of the stomach.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-08-25T03:38:51Z") -AnnotationAssertion( "FMA:63464") -AnnotationAssertion(rdfs:label "mucous cell of stomach") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) - -# Class: (stem cell of gastric gland) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "ISBN:0517223651") "A stomach epithelial cell that is olumnar in form with a few short apical microvilli; relatively undifferentiated mitotic cell from which other types of gland are derived; few in number, situated in the isthmus region of the gland and base of the gastric pit.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-08-25T03:57:08Z") -AnnotationAssertion( "FMA:62953") -AnnotationAssertion(rdfs:label "stem cell of gastric gland") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) - # Class: (basal cell of epidermis) AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "ISBN:0517223651") "A basally situated, mitotically active, columnar-shaped keratinocyte attached to the basement membrane.") @@ -36724,32 +18644,9 @@ AnnotationAssertion( "2010-08-26T03:12:49Z") AnnotationAssertion( "FMA:70571") AnnotationAssertion(rdfs:label "basal cell of epidermis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf(Annotation( "true") ) -# Class: (glomerular endothelial cell) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:15840009") "An endothelial cell found in the glomerulus of the kidney. This cell is flattened, highly fenestrated, and plays a vital role in the formation of glomerular ultrafiltrate.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-08-26T10:59:44Z") -AnnotationAssertion( "BTO:0004632") -AnnotationAssertion( "FMA:70970") -AnnotationAssertion(rdfs:label "glomerular endothelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) - -# Class: (granulocytopoietic cell) - -AnnotationAssertion(Annotation( "GOC:tfm") "A cell involved in the formation of a granulocyte.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-08-30T12:54:27Z") -AnnotationAssertion( "FMA:83519") -AnnotationAssertion(rdfs:label "granulocytopoietic cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - # Class: (monopoietic cell) AnnotationAssertion(Annotation( "GOC:tfm") "A cell involved in the formation of a monocyte (monopoiesis).") @@ -36757,21 +18654,8 @@ AnnotationAssertion( "2010-08-30T01:27:48Z") AnnotationAssertion( "FMA:83552") AnnotationAssertion(rdfs:label "monopoietic cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) -# Class: (hepatic stem cell) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:26798363") "A stem cell that can give rise to the cells of the liver. The term usually refers to the self-renewing pool of hepatocyte precursors in the adult liver (differently from 'hepatoblast', often used for fetal precursors of hepatocytes).") -AnnotationAssertion( ) -AnnotationAssertion( "2010-08-30T02:00:42Z") -AnnotationAssertion( "FMA:86577") -AnnotationAssertion(Annotation( "PMID:18442648") Annotation( ) "HpSC") -AnnotationAssertion(rdfs:label "hepatic stem cell") -AnnotationAssertion(rdfs:seeAlso "https://github.com/obophenotype/cell-ontology/issues/800") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - # Class: (oncocyte) AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "ISBN:0721662544") Annotation( "PMID:20013317") "A large epithelial cell with an extremely acidophilic and granular cytoplasm, containing vast numbers of mitochondria; such cells may undergo neoplastic transformation. From the Greek word onkos meaning swelling, this cell type is found in parathyroid, salivary and thyroid glands.") @@ -36793,17 +18677,6 @@ AnnotationAssertion(rdfs:label "oxyp SubClassOf( ) SubClassOf( ) -# Class: (oxyphil cell of thyroid) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:20013317") "An oncocyte located in the thyroid.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-09-02T11:33:26Z") -AnnotationAssertion( "FMA:87169") -AnnotationAssertion( "Askanazy cells") -AnnotationAssertion( "Hurthle cells") -AnnotationAssertion(rdfs:label "oxyphil cell of thyroid") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (epithelial cell of tracheobronchial tree) AnnotationAssertion(Annotation( "GOC:tfm") "An epithelial cell of the tracheobronchial tree.") @@ -36813,68 +18686,8 @@ AnnotationAssertion( AnnotationAssertion( "FMA:66816") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "epithelial cell of tracheobronchial tree") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (brush cell of epithelium proper of large intestine) - -AnnotationAssertion(Annotation( "GOC:tfm") "Brush cell found in the epithelial layer of the colon.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-09-02T02:20:50Z") -AnnotationAssertion( "FMA:263222") -AnnotationAssertion(Annotation( "http://orcid.org/0000-0003-4183-8865") "brush cell of large intestine") -AnnotationAssertion(Annotation( "http://orcid.org/0000-0003-4183-8865") "tuft cell of epithelium of large intestine") -AnnotationAssertion(Annotation( "http://orcid.org/0000-0003-4183-8865") "tuft cell of large intestine") -AnnotationAssertion(rdfs:comment "Brush cells are a distinct cell type from brush border cell-types.") -AnnotationAssertion(rdfs:label "brush cell of epithelium proper of large intestine") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (brush cell) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "ISBN:0517223651") Annotation( "PMID:15817800") "A cell type found in the gastrointestinal and respiratory tracts that is characterized by the presence of a tuft of blunt, squat microvilli (120-140 per cell). Function of this cell type is not known.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-09-02T02:28:53Z") -AnnotationAssertion( "FMA:67978") -AnnotationAssertion( "caveolated cell") -AnnotationAssertion( "fibrillovesicular cell") -AnnotationAssertion( "multivesicular cell") -AnnotationAssertion( "tuft cell") -AnnotationAssertion(rdfs:label "brush cell") -SubClassOf( ) - -# Class: (brush cell of lobular bronchiole) - -AnnotationAssertion(Annotation( "GOC:tfm") "A brush cell found in the epithelium of lobular bronchiole.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-09-02T02:38:34Z") -AnnotationAssertion( "FMA:263220") -AnnotationAssertion(rdfs:label "brush cell of lobular bronchiole") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (brush cell of terminal bronchiole) - -AnnotationAssertion(Annotation( "GOC:tfm") "A brush cell of the epithelium in the terminal bronchiole.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-09-02T02:38:36Z") -AnnotationAssertion( "FMA:263228") -AnnotationAssertion(rdfs:label "brush cell of terminal bronchiole") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (brush cell of trachea) - -AnnotationAssertion(Annotation( "GOC:tfm") "Brush cell of the epithelium in the trachea.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "2010-09-02T02:38:37Z") -AnnotationAssertion( "FMA:263224") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "brush cell of trachea") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) - # Class: (brush cell of bronchus) AnnotationAssertion(Annotation( "GOC:tfm") "A brush cell found in the epithelium of bronchus.") @@ -36884,7 +18697,6 @@ AnnotationAssertion( AnnotationAssertion( "FMA:263226") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "brush cell of bronchus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (intermediate epitheliocyte) @@ -36915,76 +18727,8 @@ AnnotationAssertion( "vertebrate lens cell") SubClassOf( ) SubClassOf( ) -SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (lens epithelial cell) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "ISBN:0721662544") Annotation( "http://en.wikipedia.org/wiki/Lens_%28anatomy%29#Lens_epithelium") "A cell of the cuboidal epithelium that covers the lens. The cells of the lens epithelium regulate most of the homeostatic functions of the lens. As ions, nutrients, and liquid enter the lens from the aqueous humor, Na+/K+ ATPase pumps in the lens epithelial cells pump ions out of the lens to maintain appropriate lens osmolarity and volume, with equatorially positioned lens epithelium cells contributing most to this current. The activity of the Na+/K+ ATPases keeps water and current flowing through the lens from the poles and exiting through the equatorial regions. The cells of the lens epithelium also serve as the progenitors for new lens fibers. It constantly lays down fibers in the embryo, fetus, infant, and adult, and continues to lay down fibers for lifelong growth.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "2010-09-07T10:45:47Z") -AnnotationAssertion( "FMA:67559") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "lens epithelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) - -# Class: (epithelial cell of prostate) - -AnnotationAssertion(Annotation( "GOC:tfm") "An epithelial cell of the prostate.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-09-07T01:49:29Z") -AnnotationAssertion( "FMA:256163") -AnnotationAssertion( "FMA:66817") -AnnotationAssertion( "prostate epithelial cell") -AnnotationAssertion(rdfs:label "epithelial cell of prostate") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (epithelial cell of prostatic duct) - -AnnotationAssertion(Annotation( "GOC:tfm") "An epithelial cell of prostatic duct.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-09-07T01:55:51Z") -AnnotationAssertion( "FMA:74224") -AnnotationAssertion(Annotation( "FMA:74224") "ductal epithelial cell of prostate") -AnnotationAssertion(rdfs:label "epithelial cell of prostatic duct") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) - -# Class: (epithelial cell of prostatic acinus) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMCID:PMC2673349") "An epithelial cell of the prostatic acinus.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-09-07T01:55:53Z") -AnnotationAssertion( "FMA:74223") -AnnotationAssertion(Annotation( "FMA:74223") "acinar epithelial cell of prostate") -AnnotationAssertion(rdfs:label "epithelial cell of prostatic acinus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (basal cell of prostatic acinus) - -AnnotationAssertion(Annotation( "GOC:tfm") "A cell of the basal layer of the epithelium in the prostatic acinus.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-09-07T01:59:08Z") -AnnotationAssertion( "FMA:74265") -AnnotationAssertion(Annotation( "FMA:74265") "basal epithelial cell of prostatic acinus") -AnnotationAssertion(rdfs:label "basal cell of prostatic acinus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (basal epithelial cell of prostatic duct) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:15226377") "A cell that constitutes the basal layer of epithelium in the prostatic duct.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-09-07T01:59:12Z") -AnnotationAssertion( "FMA:74226") -AnnotationAssertion(rdfs:label "basal epithelial cell of prostatic duct") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (marrow fibroblast) AnnotationAssertion(Annotation( "GOC:tfm") "A fibroblast in the bone marrow.") @@ -36992,58 +18736,8 @@ AnnotationAssertion( "2010-09-07T02:25:18Z") AnnotationAssertion( "FMA:84377") AnnotationAssertion(rdfs:label "marrow fibroblast") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (pulmonary interstitial fibroblast) - -AnnotationAssertion(Annotation( "GOC:tfm") "A fibroblasts found in interstitial spaces in the pulmonary tract. Greater numbers of these cells are found in idiopathic pulmonary fibrosis.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "2010-09-07T02:29:38Z") -AnnotationAssertion( "FMA:84467") -AnnotationAssertion( "pulmonary myofibroblast") -AnnotationAssertion( "pulmonary septal cell") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "pulmonary interstitial fibroblast") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (nucleate cell) - -AnnotationAssertion(Annotation( "GOC:tfm") "A cell containing at least one nucleus.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-09-07T03:32:33Z") -AnnotationAssertion( "FMA:67513") -AnnotationAssertion(rdfs:label "nucleate cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (smooth muscle cell of sphincter of pupil) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "ISBN:0721662544") Annotation( "ISBN:0721694128") "A circular smooth muscle cell of the iris, innervated by the ciliary nerves (parasympathetic), and acting to contract the pupil. This muscle cell derives from neuroectoderm. This smooth muscle cell results from transformation of epithelial cells to smooth muscle cells.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-09-08T08:53:42Z") -AnnotationAssertion( "FMA:70611") -AnnotationAssertion( "smooth muscle fiber of sphincter of pupil") -AnnotationAssertion( "smooth muscle fibre of sphincter of pupil") -AnnotationAssertion(rdfs:label "smooth muscle cell of sphincter of pupil") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (peripheral blood stem cell) - -AnnotationAssertion(Annotation( "GOC:tfm") "A hematopoeitic stem cell found in the blood. Normally found in very limited numbers in the peripheral circulation (less than 0.1% of all nucleated cells).") -AnnotationAssertion( ) -AnnotationAssertion( "2010-09-07T03:57:09Z") -AnnotationAssertion( "BTO:0002669") -AnnotationAssertion( "FMA:86711") -AnnotationAssertion( "MESH:D000072916") -AnnotationAssertion( "PBSC") -AnnotationAssertion(rdfs:label "peripheral blood stem cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - # Class: (pluripotent stem cell) AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:19343304") "A pluripotent stem cell has the ability to form cells from all three germ layers (ectoderm, mesoderm, and endoderm). However, unlike totipotent stem cells, they cell can not generate all the cells of the whole organism such as placenta.") @@ -37054,76 +18748,14 @@ AnnotationAssertion( "pluripotent stem cell") SubClassOf( ) -# Class: (intestinal crypt stem cell) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "ISBN:0517223651") "A cell that is found in a zone occupying the bottom region of the crypt; provide the source of most of the cell types of the intestinal epithelium; proliferate by mitotic division; differentiates into columnar or goblet cells.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-09-08T09:21:22Z") -AnnotationAssertion( "FMA:63379") -AnnotationAssertion( "stem cell of intestinal crypt of Lieberkuhn") -AnnotationAssertion(rdfs:label "intestinal crypt stem cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - # Class: (epithelial cell of alimentary canal) AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "ISBN:0721662544") "An epithelial cell of the musculomembranous digestive tube extending from the mouth to the anus.") AnnotationAssertion( ) AnnotationAssertion( "2010-09-08T09:26:53Z") AnnotationAssertion(rdfs:label "epithelial cell of alimentary canal") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (epithelial cell of esophagus) - -AnnotationAssertion(Annotation( "GOC:tfm") "An epithelial cell of the esophagus.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-09-08T09:28:20Z") -AnnotationAssertion( "FMA:63071") -AnnotationAssertion(rdfs:label "epithelial cell of esophagus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (epithelial cell of large intestine) - -AnnotationAssertion(Annotation( "GOC:tfm") "An epithelial cell of the large intestine.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-09-08T09:28:22Z") -AnnotationAssertion( "BTO:0004297") -AnnotationAssertion( "FMA:256157") -AnnotationAssertion( "epithelial cell of colon") -AnnotationAssertion(rdfs:label "epithelial cell of large intestine") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (epithelial cell of small intestine) - -AnnotationAssertion(Annotation( "GOC:tfm") "An epithelial cell of the small intestine.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-09-08T09:41:46Z") -AnnotationAssertion( "FMA:256159") -AnnotationAssertion(rdfs:label "epithelial cell of small intestine") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (stromal cell of endometrium) - -AnnotationAssertion(Annotation( "PMID:11331626") Annotation( "PMID:30013421") Annotation( "PMID:30309298") Annotation( "Wiki:Decidualization&oldid=908981933#Endometrial_stromal_cells_(ESCs)") Annotation( "https://doi.org/10.1038/s41591-020-1040-z") "A stromal cell of the endometrium that is fibroblastic in appearance. During decidualization this cell may differentiate into a decidual stromal cell.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "2010-09-08T09:50:04Z") -AnnotationAssertion( "CALOHA:TS-1266") -AnnotationAssertion( "FMA:86490") -AnnotationAssertion( "endometrial stromal cell") -AnnotationAssertion(Annotation( "PMID:30309298") "endometrial stromal fibroblast") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "stromal cell of endometrium") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (supporting cell of carotid body) AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:8985136") Annotation( "http://www.copewithcytokines.de/cope.cgi?key=glomus%20cells") "A supportive cell that has characteristics of glial cell. Processes of this cell envelope the junctions between glomus cells and nerve endings.") @@ -37143,7 +18775,6 @@ AnnotationAssertion( AnnotationAssertion( "FMA:256167") AnnotationAssertion( "MESH:D000072637") AnnotationAssertion(rdfs:label "epithelial cell of thyroid gland") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf(Annotation( "true") ) @@ -37168,108 +18799,9 @@ AnnotationAssertion( "2010-09-08T02:29:38Z") AnnotationAssertion( "FMA:70547") AnnotationAssertion(rdfs:label "epithelial cell of parathyroid gland") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf(Annotation( "true") ) -# Class: (endothelial cell of viscerocranial mucosa) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "ISBN:0618947256") "An endothelial cell found in the mucosa associated with the facial skeleton.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-09-14T10:40:12Z") -AnnotationAssertion( "FMA:70627") -AnnotationAssertion(rdfs:label "endothelial cell of viscerocranial mucosa") -SubClassOf( ) - -# Class: (endothelial cell of sinusoid) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "ISBN:0618947256") "An endothelial cell that lines any of the venous cavities through which blood passes in various glands and organs such as the spleen and liver.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "2010-09-14T10:57:26Z") -AnnotationAssertion( "FMA:63134") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "endothelial cell of sinusoid") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (type A cell of stomach) - -AnnotationAssertion(Annotation( "GOC:tfm") "A type of enteroendocrine cell found in the stomach that secretes glucagon.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-09-10T10:54:42Z") -AnnotationAssertion( "FMA:83411") -AnnotationAssertion(rdfs:label "type A cell of stomach") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (type D cell of colon) - -AnnotationAssertion(Annotation( "GOC:tfm") "A D cell located in the colon.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-09-10T11:37:35Z") -AnnotationAssertion( "FMA:268744") -AnnotationAssertion( "colon D-cell") -AnnotationAssertion( "colonic delta cell") -AnnotationAssertion( "delta cell of colon") -AnnotationAssertion(rdfs:label "type D cell of colon") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (type D cell of small intestine) - -AnnotationAssertion(Annotation( "GOC:tfm") "A type D cell of the small intestine.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-09-10T01:34:22Z") -AnnotationAssertion( "FMA:268736") -AnnotationAssertion( "delta cell of small intestine") -AnnotationAssertion( "small intestine D-cell") -AnnotationAssertion( "small intestine delta cell") -AnnotationAssertion(rdfs:label "type D cell of small intestine") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (type D cell of stomach) - -AnnotationAssertion(Annotation( "GOC:tfm") "A type D cell found in the stomach.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-09-10T01:36:03Z") -AnnotationAssertion( "FMA:83410") -AnnotationAssertion( "delta cell of stomach") -AnnotationAssertion( "stomach D-cell") -AnnotationAssertion( "stomach delta cell") -AnnotationAssertion(rdfs:label "type D cell of stomach") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (histamine secreting cell) - -AnnotationAssertion(Annotation( "GOC:tfm") "A cell type that secretes histamine.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-09-10T03:04:42Z") -AnnotationAssertion(rdfs:label "histamine secreting cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (pancreatic PP cell) - -AnnotationAssertion(Annotation( "GOC:tfm") "A PP cell located in the islets of the pancreas.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "2010-09-10T03:30:31Z") -AnnotationAssertion( "BTO:0000805") -AnnotationAssertion( "FMA:70588") -AnnotationAssertion( "MESH:D050418") -AnnotationAssertion( "PP cell of pancreatic islet") -AnnotationAssertion( "PP-cell of pancreatic islet") -AnnotationAssertion( "pancreatic polypeptide-secreting cell") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "The term PP cell of pancreatic acinus was obsoleted due to a lack of evidence, making PP cell of pancreatic islets synonymous with pancreatic PP cell.") -AnnotationAssertion(rdfs:label "pancreatic PP cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - # Class: (type I cell of carotid body) AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "ISBN:0517223651") "A round or oval neuroepithelial cell that contacts other type I cells or capillaries. They occur in clusters that are surrounded by sheath cells (type-II cells) in the carotid body. This cell type is capable of secreting a number of neurotransmitters.") @@ -37294,7 +18826,6 @@ AnnotationAssertion( "epithelial reticular cell of thymus") AnnotationAssertion( "thymic epithelial cell") AnnotationAssertion(rdfs:label "epithelial cell of thymus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) # Class: (type-1 epithelial cell of thymus) @@ -37303,68 +18834,10 @@ AnnotationAssertion(Annotation( ) AnnotationAssertion( "2010-09-13T02:37:23Z") AnnotationAssertion( "FMA:72209") -AnnotationAssertion( "subcapsular thymic epithelial cell") +AnnotationAssertion(Annotation( "PMID:18194204") Annotation( "PMID:2694455") "subcapsular thymic epithelial cell") AnnotationAssertion(rdfs:label "type-1 epithelial cell of thymus") SubClassOf( ) -# Class: (type B synovial cell) - -AnnotationAssertion(Annotation( ) Annotation( "GOC:tfm") Annotation( "ISBN:0517223651") Annotation( "PMID:34433485") Annotation( "PMID:34772990") "A resident stromal cell located in the synovial membrane and responsible for the production of immune-related cytokines and chemokines. This cell type secretes glycoproteins and hyaluronic acid, has abundant granular endoplasmic reticulum, but contains fewer vacuoles and vesicles.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-09-13T03:39:14Z") -AnnotationAssertion( "BTO:0003652") -AnnotationAssertion( "FMA:66788") -AnnotationAssertion( "fibroblast-like synoviocyte") -AnnotationAssertion(Annotation( "PMID:23147896") "synovial fibroblast") -AnnotationAssertion(Annotation( "PMID:34433485") Annotation( "https://en.wikipedia.org/wiki/Fibroblast-like_synoviocyte") rdfs:comment "Type B synovial cells play a key role in the pathogenesis of chronic inflammatory diseases, such as rheumatoid arthritis, and are essential for the maintenance of normal joint functions. Fibroblast-like synoviocytes from different joints have different properties, which may contribute to the characteristic pattern of joint involvement in different types of arthritis.") -AnnotationAssertion(rdfs:label "type B synovial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (epithelial cell of distal tubule) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "ISBN:0517223651") "An epithelial cell of the distal convoluted tubule of the kidney that helps regulate systemic levels of potassium, sodium, calcium, and pH.") -AnnotationAssertion( "FMA:62125") -AnnotationAssertion( "FMA:70981") -AnnotationAssertion( "KUPO:0001055") -AnnotationAssertion( "kidney distal tubule epithelial cell") -AnnotationAssertion(rdfs:label "epithelial cell of distal tubule") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf(Annotation( "true") ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (epithelial cell of proximal tubule) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "ISBN:1-4160-2328-3") "An epithelial cell of the proximal tubule of the kidney.") -AnnotationAssertion( ) -AnnotationAssertion( "FMA:62125") -AnnotationAssertion( "FMA:70973") -AnnotationAssertion( "KUPO:0001044") -AnnotationAssertion( "kidney proximal tubule epithelial cell") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "epithelial cell of proximal tubule") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (epithelial cell of skin gland) - -AnnotationAssertion(Annotation( "GOC:tfm") "An epithelial cell of a skin gland.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-09-14T12:00:07Z") -AnnotationAssertion( "FMA:70657") -AnnotationAssertion( "epithelial cell of gland of skin") -AnnotationAssertion(rdfs:label "epithelial cell of skin gland") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - # Class: (somatotroph) AnnotationAssertion(Annotation( "SANBI:mhl") "An acidophilic cell of the anterior pituitary that produces growth hormone, somatotropin.") @@ -37379,31 +18852,6 @@ AnnotationAssertion(rdfs:label "soma SubClassOf( ) SubClassOf( ) -# Class: (endocrine-paracrine cell of prostate gland) - -AnnotationAssertion(Annotation( "GOC:tfm") "An ecto-epithelial cell of the prostate gland that secretes hormones.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "2010-09-14T03:01:58Z") -AnnotationAssertion( "CALOHA:TS-1280") -AnnotationAssertion( "FMA:74390") -AnnotationAssertion( "FMA:86774") -AnnotationAssertion( "glandular cell of prostate") -AnnotationAssertion( "neuro-epithelial cell of prostate gland") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "endocrine-paracrine cell of prostate gland") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (supporting cell of cochlea) - -AnnotationAssertion(Annotation( "GOC:tfm") "An epithelial supporting cell located in the cochlea.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-09-14T03:31:38Z") -AnnotationAssertion( "FMA:79796") -AnnotationAssertion(rdfs:label "supporting cell of cochlea") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (supporting cell of vestibular epithelium) AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:20837532") "A supporting cell of the vestibular epithelium.") @@ -37411,7 +18859,6 @@ AnnotationAssertion( "2010-09-14T03:31:44Z") AnnotationAssertion( "FMA:75607") AnnotationAssertion(rdfs:label "supporting cell of vestibular epithelium") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (neural cell) @@ -37421,9 +18868,6 @@ AnnotationAssertion( AnnotationAssertion( "CALOHA:TS-2040") AnnotationAssertion( "FMA:70333") AnnotationAssertion(rdfs:label "neural cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) # Class: (connective tissue cell) @@ -37436,9 +18880,6 @@ AnnotationAssertion( "MESH:D003239") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "connective tissue cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf(Annotation( "true") ) # Class: (embryonic cell (metazoa)) @@ -37450,17 +18891,7 @@ AnnotationAssertion( "FMA:82841") AnnotationAssertion( "WBbt:0007028") AnnotationAssertion(rdfs:label "embryonic cell (metazoa)") -SubClassOf( ) - -# Class: (amniocyte) - -AnnotationAssertion(Annotation( "BFO:0000066") Annotation( "GOC:tfm") Annotation( "PMID:3211847") "A cell of a fetus which is suspended in the amniotic fluid. Amniocytes are considered to arise from several tissues including fetal skin, the fetal urinary tract, umbilical cord, and the inner amniotic surface.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-09-20T10:13:37Z") -AnnotationAssertion( "BTO:0000066") -AnnotationAssertion(rdfs:label "amniocyte") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) +SubClassOf( ) # Class: (myoepithelial cell of mammary gland) @@ -37472,47 +18903,8 @@ AnnotationAssertion( "FMA:67800") "basal cell of lactiferous duct") AnnotationAssertion( "myoepithelial cell of lactiferous gland") AnnotationAssertion(rdfs:label "myoepithelial cell of mammary gland") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (mammary alveolar cell) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:19022771") "The milk-producing cell of the alveolar unit that emerges during pregnancy.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-09-20T01:30:57Z") -AnnotationAssertion( "FMA:74506") -AnnotationAssertion( "FMA:79866") -AnnotationAssertion( "epithelial cell of lactiferous gland") -AnnotationAssertion( "luminal cell of alveolus of lactiferous gland") -AnnotationAssertion( "mammary alveolar epithelial cell") -AnnotationAssertion( "mammary gland alveolar epithelial cell") -AnnotationAssertion(rdfs:label "mammary alveolar cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf(Annotation( "true") ) - -# Class: (mammary gland epithelial cell) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:19022771") "An epithelial cell of the mammary gland.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-09-20T01:49:37Z") -AnnotationAssertion( "BTO:0004300") -AnnotationAssertion( "breast epithelial cell") -AnnotationAssertion( "mammary epithelial cell") -AnnotationAssertion(rdfs:label "mammary gland epithelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (bronchial epithelial cell) - -AnnotationAssertion(Annotation( "GOC:tfm") "An epithelial cell of the bronchus.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-09-20T02:00:00Z") -AnnotationAssertion( "BTO:0002922") -AnnotationAssertion(rdfs:label "bronchial epithelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (basal epithelial cell of tracheobronchial tree) AnnotationAssertion(Annotation( "GOC:tfm") "An epithelial cell type that lacks the columnar shape typical for other respiratory epithelial cells. This cell type is able to differentiate into other respiratory epithelial cells in response to injury.") @@ -37531,18 +18923,8 @@ AnnotationAssertion( "2010-09-20T02:21:12Z") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "ciliated cell of the bronchus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (neural crest derived fat cell) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:17507398") "A fat cell derived from a neural crest cell.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-09-20T02:25:25Z") -AnnotationAssertion(rdfs:label "neural crest derived fat cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (preadipocyte) AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:18793119") "An undifferentiated fibroblast that can be stimulated to form a fat cell.") @@ -37560,99 +18942,6 @@ AnnotationAssertion( AnnotationAssertion(rdfs:label "brown preadipocyte") SubClassOf( ) -# Class: (buccal mucosa cell) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "MESH:D009061") "An endothelial cell that lines the oral cavitiy including the mucosa of the gums, the palate, the lip, and the cheek.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-09-20T02:52:54Z") -AnnotationAssertion(rdfs:label "buccal mucosa cell") -SubClassOf( ) - -# Class: (prostate stem cell) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:15226377") "A prostate epithelial cell that is CD133-positive, CD44-positive, integrin A2beta3-high. This cell is a stem cell for the prostate epithelium.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-09-20T03:21:06Z") -AnnotationAssertion( "CD133-positive prostate epithelial cell") -AnnotationAssertion(rdfs:label "prostate stem cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (basal cell of prostate epithelium) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMCID:PMC2673349") "An undifferentiated cell of the prostate epithelium that lacks secretory activity.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "2010-09-20T03:34:10Z") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "basal cell of prostate epithelium") -SubClassOf( ) - -# Class: (endocardial cell) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "ISSN:0452-3458") "An endothelial cell that lines the intracavitary lumen of the heart, separating the circulating blood from the underlying myocardium. This cell type releases a number of vasoactive substances including prostacyclin, nitrous oxide and endothelin.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "2010-09-21T04:33:05Z") -AnnotationAssertion( "FMA:75621") -AnnotationAssertion( "endocardial endothelial cell") -AnnotationAssertion(Annotation( "FMA:75621") "endothelial cell of endocardium") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "endocardial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (progenitor cell of endocrine pancreas) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:20025937") Annotation( "PMID:20217494") Annotation( "PMID:22728667") "A progenitor cell that is able to differentiate into the pancreas alpha, beta and delta endocrine cells. This cell type expresses neurogenin-3 and Isl-1.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-09-21T04:41:06Z") -AnnotationAssertion( "pancreatic endocrine progenitor") -AnnotationAssertion( "pancreatic islet progenitor cell") -AnnotationAssertion(rdfs:label "progenitor cell of endocrine pancreas") -SubClassOf( ) -SubClassOf( ) - -# Class: (gestational hematopoietic stem cell) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "ISBN:978-60327-246-6") "A hematopoietic stem cell that exists during embryogenesis.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-09-22T09:05:13Z") -AnnotationAssertion(rdfs:label "gestational hematopoietic stem cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (fetal liver hematopoietic progenitor cell) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "ISBN:978-1-60327-346-6") Annotation( "PMID:16569764") "A hematopoietic stem cell that resides in the fetal liver. In mice, this cell type is first observed at E10.5. This cell type is MHC-positive, HSA-positive, AA4.1-positive, CD45-positive, Sca-1 positive, CD150-positive, CD48-negative and CD244-negative.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-09-22T09:08:32Z") -AnnotationAssertion(rdfs:label "fetal liver hematopoietic progenitor cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (yolk sac hematopoietic stem cell) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "doi:10.1097/MOH.0b013e3282f97ae1") "A hematopoietic stem found in the yolk sac. In mice, this cell type is Sca-1-negative, CD45-negative, MHC-negative, HSA-positive, AA4.1-positive, CD44-positive.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-09-22T09:08:34Z") -AnnotationAssertion( "hemangioblast precursor") -AnnotationAssertion(rdfs:label "yolk sac hematopoietic stem cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (placental hematopoietic stem cell) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "ISBN:978-1-60327-346-6") "A hematopoietic stem cell of the placenta. This cell type is first observed E10.5 This cell type may give rise to fetal liver hematopoietic stem cells.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-09-22T10:30:02Z") -AnnotationAssertion(rdfs:label "placental hematopoietic stem cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - # Class: (cerebellar granule cell precursor) AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:14745007") "A cell located in the outermost proliferative zone of the external germinal layer that can differentiate into astroglial cells and granule cells. This cell type is glial fibrillary acidic protein-positive and HNK1-positive.") @@ -37665,21 +18954,6 @@ AnnotationAssertion(rdfs:label "cere SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (keratocyte) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "ISBN:978-0-7020-2958-5") "A keratocyte is a specialized fibroblast residing in the cornea stroma that has a flattened, dendritic cell located between the lamellae with a large flattened nucleus and lengthy processes which communicate with neighboring cells. This corneal layer, representing about 85-90% of corneal thickness, is built up from highly regular collagenous lamellae and extracellular matrix components. Keratocytes play the major role in keeping it transparent, healing its wounds, and synthesizing its components. This cell type secretes collagen I, V, VI, and keratin sulfate.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "2010-09-22T01:57:40Z") -AnnotationAssertion( "corneal fibroblast") -AnnotationAssertion( "corneal keratocyte") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "keratocyte") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (cortical thymic epithelial cell) AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:18403190") "An epithelial cell of the cortical portion of the thymus. Epithelial cells in this region are required for positive selection of CD8-positive T cells.") @@ -37690,30 +18964,8 @@ AnnotationAssertion( "cTEC") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "cortical thymic epithelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (medullary thymic epithelial cell) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:18180458") "An epithelial cell of the medullary thymus. This cell type expresses a diverse range of tissue-specific antigens. This promiscuous gene expression is a cell-autonomous property of medullary epithelial cells and is maintained during the entire period of thymic T cell output.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-09-23T03:17:14Z") -AnnotationAssertion( "BTO:0004563") -AnnotationAssertion( "mTEC") -AnnotationAssertion(rdfs:label "medullary thymic epithelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (myometrial cell) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:11429640") "A smooth muscle cell of the myometrium that enlarges and stretches during pregnancy, and contracts in response to oxytocin.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-09-23T03:46:34Z") -AnnotationAssertion( "BTO:0004519") -AnnotationAssertion( "myometrium smooth muscle cell") -AnnotationAssertion(rdfs:label "myometrial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (trabecular meshwork cell) AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:14500801") "A cell that lines the trabecular meshwork, which is an area of tissue in the eye located around the base of the cornea, near the ciliary body, and is responsible for draining the aqueous humor from the eye via the anterior chamber (the chamber on the front of the eye covered by the cornea). This cell may play a role in regulating intraocular pressure.") @@ -37721,7 +18973,6 @@ AnnotationAssertion( "2010-09-23T04:18:50Z") AnnotationAssertion( "trabeculocyte") AnnotationAssertion(rdfs:label "trabecular meshwork cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) # Class: (respiratory epithelial cell) @@ -37732,134 +18983,8 @@ AnnotationAssertion( AnnotationAssertion( "BTO:0004533") AnnotationAssertion( "airway epithelial cell") AnnotationAssertion(rdfs:label "respiratory epithelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) -# Class: (respiratory goblet cell) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "ISBN:0721662544") "A simple columnar epithelial cell that secretes mucin. Rough endoplasmic reticulum, mitochondria, the nucleus, and other organelles are concentrated in the basal portion. The apical plasma membrane projects microvilli to increase surface area for secretion.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-09-23T04:42:27Z") -AnnotationAssertion(Annotation( "MP:0010863") "respiratory mucosa goblet cells") -AnnotationAssertion(rdfs:label "respiratory goblet cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (somatic cell) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "ISBN:0721662544") "A cell of an organism that does not pass on its genetic material to the organism's offspring (i.e. a non-germ line cell).") -AnnotationAssertion( ) -AnnotationAssertion( "2010-09-24T09:44:42Z") -AnnotationAssertion( "BTO:0001268") -AnnotationAssertion( "FMA:72300") -AnnotationAssertion( "WBbt:0008378") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "somatic cell") -SubClassOf( ) -SubClassOf( ) - -# Class: (myotube) - -AnnotationAssertion(Annotation( "GOC:dos") Annotation( "GOC:tfm") Annotation( "ISBN:0323052908") Annotation( "PMID:22274696") "A transversely striated, synctial muscle cell, formed by the fusion of myoblasts.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-09-24T01:13:01Z") -AnnotationAssertion( "FBbt:00005812") -AnnotationAssertion( "myotubule") -AnnotationAssertion( "single cell sarcomere") -AnnotationAssertion(rdfs:label "myotube") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (ear hair cell) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tfm") Annotation( "ISBN:0192801023") "A hair cell of the ear that contains the organs of balance and hearing.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-09-24T01:49:31Z") -AnnotationAssertion( "ear receptor cell") -AnnotationAssertion(rdfs:label "ear hair cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (Schwann cell precursor) - -AnnotationAssertion(Annotation( "GOC:tfm") "A giioblast cell that develops from a migratory neural crest cell. The SCP is embedded among neurons (axons) with minimal extracellular spaces separating them from nerve cell membranes and has no basal lamina. In rodents SCPs are the only cells in the Schwann cell linage that expresses Cdh19.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-09-24T02:06:10Z") -AnnotationAssertion( "Schwann cell precursor cell") -AnnotationAssertion(rdfs:label "Schwann cell precursor") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (immature Schwann cell) - -AnnotationAssertion(Annotation( "GOC:cvs") Annotation( "GOC:tfm") Annotation( "ISBN:0721662544") "A glial cell that develops from a Schwann cell precursor. The immature Schwann cell is embedded among neurons (axons) with minimal extracellular spaces separating them from nerve cell membranes and has a basal lamina. Cells can survive without an axon present. Immature Schwann cell can be found communally ensheathing large groups of axons.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-09-24T02:10:31Z") -AnnotationAssertion( "Schwann cell") -AnnotationAssertion( "ZFA:0001725") -AnnotationAssertion(rdfs:label "immature Schwann cell") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (intermediate monocyte) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:20628149") Annotation( "PMID:20870168") "A monocyte that has characteristics of both patrolling and inflammatory monocytes.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-10-04T10:52:03Z") -AnnotationAssertion(rdfs:label "intermediate monocyte") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (Gr1-high classical monocyte) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:20628149") Annotation( "PMID:8890901") Annotation( "http://www.immgen.org/index_content.html") "A resident monocyte that is Gr-1 high, CD43-negative, CX3CR1-negative, CD115-positive, and B220-negative.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-10-04T11:26:18Z") -AnnotationAssertion(rdfs:comment "Markers are associated with mice. The Gr epitope is used to describe this cell type is found on both Ly6c and Ly6g. However, its the Ly6c that is considered the specific marker, and thus used in the cross-product.") -AnnotationAssertion(rdfs:label "Gr1-high classical monocyte") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (CD14-positive, CD16-positive monocyte) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:20628149") Annotation( "PMID:21937707") Annotation( "PMID:22343568") "A CD14-positive monocyte that is also CD16-positive and CCR2-negative.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-10-04T12:49:47Z") -AnnotationAssertion(Annotation( "PMID:22343568") "CD16+ monocyte") -AnnotationAssertion(rdfs:comment "This cell type is compatible with the HIPC Lyoplate markers for 'CD16+ monocyte'. Markers are associated with human cells. Note that this cell type encompasses both human intermediate monocytes (CD14+, CD16-low), and human non-classical monocytes (CD14-low, CD16+).") -AnnotationAssertion(rdfs:label "CD14-positive, CD16-positive monocyte") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (Gr1-positive, CD43-positive monocyte) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:20628149") "An intermediate monocyte that is Gr1-positive, CD43-positive.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-10-04T12:49:49Z") -AnnotationAssertion(rdfs:label "Gr1-positive, CD43-positive monocyte") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (fraction B/C precursor B cell) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "http://www.immgen.org/index_content.html") "A precursor B cell that is AA4-positive, IgM-negative, CD19-positive, CD43-positive and HSA-positive.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-10-05T10:11:38Z") -AnnotationAssertion(rdfs:label "fraction B/C precursor B cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (Peyer's patch B cell) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "http://www.immgen.org/index_content.html") "A resting mature B cell within the Peyer's patch that is CD19-positive, B220-positive, IgM-positive, AA4-negative, CD23-positive, CD43-negative, and CD5-negative.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-10-05T11:18:03Z") -AnnotationAssertion( "Peyers patch B cell") -AnnotationAssertion(rdfs:label "Peyer's patch B cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - # Class: (immature T cell) AnnotationAssertion(Annotation( "GOC:tfm") "A T cell that has not completed T cell selection.") @@ -37870,234 +18995,8 @@ AnnotationAssertion( "immature T-cell") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "immature T cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) -# Class: (nucleated reticulocyte) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:18182572") Annotation( "PMID:9011180") Annotation( "PMID:9046052") "A reticulocyte that retains the nucleus and other organelles. Found in birds, fish, amphibians and reptiles.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-10-15T09:24:05Z") -AnnotationAssertion(rdfs:label "nucleated reticulocyte") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (enucleated reticulocyte) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "ISBN:0-12203-052-4") Annotation( "ISBN:0721601464") "A reticulocyte lacking a nucleus and showing a basophilic reticulum under vital staining due to the presence of ribosomes.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-10-15T09:24:08Z") -AnnotationAssertion( "CALOHA:TS-0864") -AnnotationAssertion( "FMA:66785") -AnnotationAssertion(rdfs:label "enucleated reticulocyte") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (early T lineage precursor) - -AnnotationAssertion(Annotation( "GOC:dsd") Annotation( "GOC:tfm") Annotation( "PMID:16551251") Annotation( "http://www.immgen.org/index_content.html") "A pro-T cell that is lin-negative, CD25-negative, CD127-negative, CD44-positive and kit-positive.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "2010-10-21T01:16:24Z") -AnnotationAssertion( "ETP") -AnnotationAssertion( "preT.ETP.Th") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "ETPs are reportedly CD1a-negative, CD4-negative, CD7-positive, CD8a-negative, CD8b-negative, CD33-low, CD34-high, CD38-low, CD45RA-positive, and CD45RO-negative.") -AnnotationAssertion(rdfs:label "early T lineage precursor") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (oligodendrocyte precursor cell) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:10704434") Annotation( "PMID:11756508") Annotation( "PMID:20142420") Annotation( "PMID:2182078") Annotation( "PMID:24133281") Annotation( "PMID:9826671") "A progenitor cell of the central nervous system that can differentiate into oligodendrocytes or type-2 astrocytes. This cell originates from multiple structures within the developing brain including the medial ganglion eminence and the lateral ganglionic eminence. These cells migrate throughout the central nervous system and persist into adulthood where they play an important role in remyelination of injured neurons.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "2010-11-10T02:51:34Z") -AnnotationAssertion(Annotation( "PMID:2253328") "oligodendrocyte-type 2 astrocyte (O-2A) progenitor cell") -AnnotationAssertion(Annotation( ) Annotation( "PMID:24133281") "oligodendrocyte/type-2 astrocyte progenitor cell") -AnnotationAssertion( "MESH:D000073637") -AnnotationAssertion(Annotation( "PMID:24133281") Annotation( ) "O-2A/OPC") -AnnotationAssertion(Annotation( "PMID:11756508") Annotation( ) "O2A/OPC") -AnnotationAssertion( ) -AnnotationAssertion(Annotation( "ISBN:9780702028991") Annotation( "PMID:10704434") Annotation( "PMID:2182078") rdfs:comment "This cell type can be purified from optic nerves and other regions of the embryonic, postnatal and adult rat CNS and can be differentiated in vitro to oligodendrocytes and type-2 astrocytes. Some references use the terms 'oligodendrocyte precursor cell' and 'oligodendrocyte type-2 astrocyte (O-2A) progenitor' to refer to the same entity (e.g., PMID:10704434), while others describe an oligodendrocyte type-2 astrocyte (O-2A) progenitor cell as the precurosr to oligodendrocyte- and type-2 astrocyte- progenitor cells (e.g, ISBN:9780702028991).") -AnnotationAssertion(rdfs:label "oligodendrocyte precursor cell") -SubClassOf( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (Cd4-negative, CD8_alpha-negative, CD11b-positive dendritic cell) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "http://www.immgen.org/index_content.html") "Cd4-negative, CD8_alpha-negative, CD11b-positive dendritic cell is a conventional dendritic cell that is CD11b-positive, CD4-negative, CD8_alpha-negative and is CD205-positive.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-11-22T01:10:28Z") -AnnotationAssertion( "DC.8-4-11b+") -AnnotationAssertion( "spleen double-negative dendritic cell") -AnnotationAssertion(rdfs:label "Cd4-negative, CD8_alpha-negative, CD11b-positive dendritic cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (epidermal Langerhans cell) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "http://www.immgen.org/index_content.html") "A Langerhans cell that is in the epidermis and is CD45-positive, MHCII-positive, and CD11b-positive.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "2010-11-22T03:57:57Z") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "epidermal Langerhans cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (CD8alpha-negative thymic conventional dendritic cell) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:19273629") Annotation( "http://www.immgen.org/index_content.html") "A conventional thymic dendritic cell that is CD8alpha-negative.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "2010-11-23T10:58:53Z") -AnnotationAssertion( "DC.8-.Th") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "CD8alpha-negative thymic conventional dendritic cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (CD11b-positive dendritic cell) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "http://www.immgen.org/index_content.html") "A conventional dendritic cell that expresses CD11b (ITGAM).") -AnnotationAssertion( ) -AnnotationAssertion( "2010-11-23T01:50:05Z") -AnnotationAssertion(rdfs:label "CD11b-positive dendritic cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (Gr1-high myeloid suppressor cell) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "http://www.immgen.org/index_content.html") "A myeloid suppressor cell that is Gr1-high and CD11c-negative.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-11-23T02:15:12Z") -AnnotationAssertion( "MDS.Gr1hi") -AnnotationAssertion(rdfs:label "Gr1-high myeloid suppressor cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (Gr1-low myeloid suppressor cell) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "http://www.immgen.org/index_content.html") "A myeloid suppressor cell that is Gr1-low and CD11c-positive.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-11-23T02:19:43Z") -AnnotationAssertion( "MDS.Gr1lo") -AnnotationAssertion(rdfs:label "Gr1-low myeloid suppressor cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (MHC-II-negative classical monocyte) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "http://www.immgen.org/index_content.html") "Gr1-high monocyte that lacks MHC-II receptor complex.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-11-23T03:27:12Z") -AnnotationAssertion( "Mo.6C+II-") -AnnotationAssertion(rdfs:label "MHC-II-negative classical monocyte") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (MHC-II-positive classical monocyte) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "http://www.immgen.org/index_content.html") "Gr1-high monocyte that has a MHC-II receptor complex.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-11-23T03:30:21Z") -AnnotationAssertion( "Mo.6c+II") -AnnotationAssertion(rdfs:label "MHC-II-positive classical monocyte") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (nasal mucosa goblet cell) - -AnnotationAssertion(Annotation( "GOC:cjm") Annotation( "GOC:tfm") "A goblet cell located in the nasal epithelium.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-12-03T03:03:02Z") -AnnotationAssertion( "MP:0002262") -AnnotationAssertion(rdfs:label "nasal mucosa goblet cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (peritubular myoid cell) - -AnnotationAssertion(Annotation( "GOC:cjm") Annotation( "GOC:tfm") Annotation( "MP:0006420") "The flattened smooth myoepithelial cells of mesodermal origin that lie just outside the basal lamina of the seminiferous tubule.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-12-03T03:11:48Z") -AnnotationAssertion(rdfs:label "peritubular myoid cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (dermal melanocyte) - -AnnotationAssertion(Annotation( "GOC:cjm") Annotation( "GOC:tfm") Annotation( "MP:0009386") "A melanocyte that produces pigment in the dermis.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-12-03T03:17:05Z") -AnnotationAssertion(rdfs:label "dermal melanocyte") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) - -# Class: (hair follicle melanocyte) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "MP:0004381") "A melanocyte that produces pigment within the hair follicle.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-12-03T03:17:09Z") -AnnotationAssertion(rdfs:label "hair follicle melanocyte") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) - -# Class: (epithelial melanocyte) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "MP:0009388") "A melanocyte that produces pigment in the epithelium.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-12-03T03:17:14Z") -AnnotationAssertion(rdfs:comment "The text defintion reference to the MP term appears to reference an epidermal melanocyte term. This term represents any melanocyte in any epithelium.") -AnnotationAssertion(rdfs:label "epithelial melanocyte") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) - -# Class: (retinal melanocyte) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "MP:0010190") "A melanocyte of the retina. This cell type is distinct from pigmented retinal epithelium.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-12-03T03:25:32Z") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "retinal melanocyte") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) - -# Class: (strial intermediate cell) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "MP:0000048") "A melanocyte located between the epithelial marginal cell layer and the mesodermal basal cell layer within the intrastrial space; the predominant cellular component of the electrogenic machinery that generates an endocochlear potential (80-100 mV) .") -AnnotationAssertion( ) -AnnotationAssertion( "2010-12-03T03:29:15Z") -AnnotationAssertion(rdfs:label "strial intermediate cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) - -# Class: (organ of Corti supporting cell) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "MP:0004300") "A supporting cell of the organ of Corti.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-12-06T03:09:01Z") -AnnotationAssertion(rdfs:label "organ of Corti supporting cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (auditory epithelial cell) - -AnnotationAssertion(Annotation( "GOC:tfm") "A specialized cell involved in auditory sensory perception.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-12-06T03:18:43Z") -AnnotationAssertion(rdfs:label "auditory epithelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - # Class: (cardiocyte) AnnotationAssertion(Annotation( "GOC:tfm") "A cell located in the heart, including both muscle and non muscle cells.") @@ -38110,9 +19009,6 @@ AnnotationAssertion( "heart cell") AnnotationAssertion(rdfs:comment "From Onard of the FMA: Cardiac muscle cell or cardiac myocyte is a striated muscle cell. Cardiocyte on the other hand is any cell in the heart which includes cells other than muscle cells (e.g. endothelial cell of endocardium). Unless there is a consensus among anatomists that cardiocytes refer only to muscle cells, we will treat them as a general class of cells in the heart.") AnnotationAssertion(rdfs:label "cardiocyte") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf(Annotation( "true") ) # Class: (spongiotrophoblast cell) @@ -38124,37 +19020,6 @@ AnnotationAssertion(rdfs:label "spon SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (adventitial cell) - -AnnotationAssertion(Annotation( "GOC:tfm") "A cell of the adventitial layer of ductal structures such as the uterer, defent duct, biliary duct, etc") -AnnotationAssertion( ) -AnnotationAssertion( "2010-12-07T04:03:56Z") -AnnotationAssertion( "BTO:0002441") -AnnotationAssertion( "FMA:84639") -AnnotationAssertion(rdfs:label "adventitial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (enteric smooth muscle cell) - -AnnotationAssertion(Annotation( "GOC:tfm") "A smooth muscle cell of the intestine.") -AnnotationAssertion( ) -AnnotationAssertion( "2011-01-17T03:39:38Z") -AnnotationAssertion( "intestinal smooth muscle cell") -AnnotationAssertion(rdfs:label "enteric smooth muscle cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (langerin-positive lymph node dendritic cell) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "http://www.immgen.org/index_content.html") "A dermal dendritic cell isolated from skin draining lymph nodes that is langerin-positive, MHC-II-positive, and CD4-negative and CD8a-negative.") -AnnotationAssertion( ) -AnnotationAssertion( "2011-01-21T01:57:00Z") -AnnotationAssertion(rdfs:label "langerin-positive lymph node dendritic cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - # Class: (kidney epithelial cell) AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "KUPO:SJ") "An epithelial cell of the kidney.") @@ -38162,21 +19027,8 @@ AnnotationAssertion( "2011-02-08T10:46:34Z") AnnotationAssertion( "KUPO:0001019") AnnotationAssertion(rdfs:label "kidney epithelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) -# Class: (subcutaneous fat cell) - -AnnotationAssertion(Annotation( "GOC:tfm") "A fat cell that is part of subcutaneous adipose tissue.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "2011-02-21T02:51:22Z") -AnnotationAssertion( "subcutaneous adipocyte") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "subcutaneous fat cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - # Class: (renal filtration cell) AnnotationAssertion(Annotation( "GOC:tfm") "A renal filtration cell is a specialized cell of the renal system that filter fluids by charge, size or both.") @@ -38186,122 +19038,6 @@ AnnotationAssertion(rdfs:label "rena SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (mesonephric podocyte) - -AnnotationAssertion(Annotation( ) Annotation( "GOC:tfm") "A specialized epithelial cell that contains \"feet\" that interdigitate with the \"feet\" of other glomerular epithelial cells in the mesonephros.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "2011-02-08T01:58:30Z") -AnnotationAssertion(Annotation( "ZFA:0001674") "mesonephric glomerular visceral epithelial cell") -AnnotationAssertion(rdfs:label "mesonephric podocyte") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (metanephric podocyte) - -AnnotationAssertion(Annotation( "GOC:tfm") "A specialized epithelial cell that contains \"feet\" that interdigitate with the \"feet\" of other glomerular epithelial cells in the metanephros.") -AnnotationAssertion( ) -AnnotationAssertion( "2011-02-08T02:02:13Z") -AnnotationAssertion(Annotation( "10.1007/s004180050142") "metanephric glomerular visceral epithelial cell") -AnnotationAssertion(rdfs:label "metanephric podocyte") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (epithelial cell of cervix) - -AnnotationAssertion(Annotation( "GOC:tfm") "An epithelial cell of the cervix.") -AnnotationAssertion( ) -AnnotationAssertion( "2011-02-24T08:20:08Z") -AnnotationAssertion(Annotation( "GOC:tfm") "cervical canal epithelial cell") -AnnotationAssertion(Annotation( "GOC:tfm") "cervical canal of uterus epithelial cell") -AnnotationAssertion(Annotation( "GOC:tfm") "cervix epithelial cell") -AnnotationAssertion(Annotation( "GOC:tfm") "cervix of uterus epithelial cell") -AnnotationAssertion(Annotation( "GOC:tfm") "epithelial cell of cervical canal") -AnnotationAssertion(Annotation( "GOC:tfm") "epithelial cell of cervical canal of uterus") -AnnotationAssertion(Annotation( "GOC:tfm") "epithelial cell of cervix of uterus") -AnnotationAssertion(Annotation( "GOC:tfm") "epithelial cell of neck of uterus") -AnnotationAssertion(Annotation( "GOC:tfm") "epithelial cell of uterine cervix") -AnnotationAssertion(Annotation( "GOC:tfm") "neck of uterus epithelial cell") -AnnotationAssertion(Annotation( "GOC:tfm") "uterine cervix epithelial cell") -AnnotationAssertion(rdfs:label "epithelial cell of cervix") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (epithelial cell of amnion) - -AnnotationAssertion(Annotation( "GOC:tfm") "An epithelial cell that is part of the amnion.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "2011-02-28T12:38:01Z") -AnnotationAssertion( "amniotic epithelial cell") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "epithelial cell of amnion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) - -# Class: (amnion mesenchymal stem cell) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:20446274") Annotation( "PMID:21339039") "A mesenchymal stem cell of the amnion membrane.") -AnnotationAssertion( ) -AnnotationAssertion( "2011-02-28T12:44:24Z") -AnnotationAssertion( "amniotic membrane stem cell") -AnnotationAssertion(rdfs:label "amnion mesenchymal stem cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (intrahepatic cholangiocyte) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:23720296") "An epithelial cell of the intrahepatic portion of the bile duct. These cells are flattened or cuboidal in shape, and have a small nuclear-to-cytoplasmic ratio relative to large/extrahepatic cholangiocytes.") -AnnotationAssertion( ) -AnnotationAssertion( "2011-02-28T01:20:20Z") -AnnotationAssertion(Annotation( "PMID:23720296") "small bile duct cholangiocyte") -AnnotationAssertion(rdfs:label "intrahepatic cholangiocyte") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (aortic smooth muscle cell) - -AnnotationAssertion(Annotation( "GOC:tfm") "A smooth muscle cell of the aorta.") -AnnotationAssertion( ) -AnnotationAssertion( "2011-02-28T01:42:12Z") -AnnotationAssertion( "BTO:0004577") -AnnotationAssertion(rdfs:label "aortic smooth muscle cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (mesenchymal stem cell of the bone marrow) - -AnnotationAssertion(Annotation( "GOC:tfm") "A mesenchymal stem cell that is part of the bone marrow.") -AnnotationAssertion( ) -AnnotationAssertion( "2011-02-28T01:47:47Z") -AnnotationAssertion(rdfs:label "mesenchymal stem cell of the bone marrow") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (chorionic membrane mesenchymal stem cell) - -AnnotationAssertion(Annotation( "GOC:tfm") "A mesenchymal stem cell of the chorionic membrane.") -AnnotationAssertion( ) -AnnotationAssertion( "2011-02-28T03:04:35Z") -AnnotationAssertion(rdfs:label "chorionic membrane mesenchymal stem cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (vein endothelial cell) - -AnnotationAssertion(Annotation( "GOC:tfm") "An endothelial cell that is part of the vein.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "2011-02-28T03:48:11Z") -AnnotationAssertion( "FMA:62104") -AnnotationAssertion( "KUPO:0001099") -AnnotationAssertion( "endothelial cell of vein") -AnnotationAssertion( "venous endothelial cell") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "vein endothelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - # Class: (embryonic blood vessel endothelial progenitor cell) AnnotationAssertion(Annotation( "GOC:tfm") "An endothelial progenitor cell that participates in angiogenesis during development.") @@ -38310,205 +19046,6 @@ AnnotationAssertion( AnnotationAssertion(rdfs:comment "See CL:0002619.") AnnotationAssertion(rdfs:label "embryonic blood vessel endothelial progenitor cell") SubClassOf( ) -SubClassOf( ) - -# Class: (fibroblast of the aortic adventitia) - -AnnotationAssertion(Annotation( "GOC:tfm") "A fibroblast of the aortic adventitia.") -AnnotationAssertion( ) -AnnotationAssertion( "2011-02-28T04:43:41Z") -AnnotationAssertion(rdfs:label "fibroblast of the aortic adventitia") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (fibroblast of cardiac tissue) - -AnnotationAssertion(Annotation( "GOC:tfm") "A fibroblast that is part of the heart.") -AnnotationAssertion( ) -AnnotationAssertion( "2011-02-28T04:57:44Z") -AnnotationAssertion( "cardiac fibroblast") -AnnotationAssertion(rdfs:label "fibroblast of cardiac tissue") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) - -# Class: (fibroblast of choroid plexus) - -AnnotationAssertion(Annotation( "GOC:tfm") "A fibroblast that is part of the choroid plexus.") -AnnotationAssertion( ) -AnnotationAssertion( "2011-02-28T05:01:39Z") -AnnotationAssertion(rdfs:label "fibroblast of choroid plexus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (fibroblast of the conjunctiva) - -AnnotationAssertion(Annotation( "GOC:tfm") "A fibroblast that is part of the conjuctiva of the eye.") -AnnotationAssertion( ) -AnnotationAssertion( "2011-02-28T05:03:44Z") -AnnotationAssertion(rdfs:label "fibroblast of the conjunctiva") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (fibroblast of dermis) - -AnnotationAssertion( ) -AnnotationAssertion( "2011-02-28T05:05:33Z") -AnnotationAssertion(rdfs:label "fibroblast of dermis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (fibroblast of gingiva) - -AnnotationAssertion( ) -AnnotationAssertion( "2011-02-28T05:09:12Z") -AnnotationAssertion(rdfs:label "fibroblast of gingiva") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (fibroblast of lung) - -AnnotationAssertion(Annotation( "GOC:tfm") "A fibroblast that is part of lung.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "2011-02-28T05:11:03Z") -AnnotationAssertion( "BTO:0000764") -AnnotationAssertion( "CALOHA:TS-0575") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "fibroblast of lung") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (fibroblast of lymphatic vessel) - -AnnotationAssertion(Annotation( "GOC:tfm") "A fibroblast of the lymphatic system.") -AnnotationAssertion( ) -AnnotationAssertion( "2011-02-28T05:16:18Z") -AnnotationAssertion(rdfs:label "fibroblast of lymphatic vessel") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (fibroblast of mammary gland) - -AnnotationAssertion(Annotation( "GOC:tfm") "A fibroblast that is part of the mammary gland.") -AnnotationAssertion( ) -AnnotationAssertion( "2011-02-28T05:18:38Z") -AnnotationAssertion(rdfs:label "fibroblast of mammary gland") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (fibroblast of periodontium) - -AnnotationAssertion(Annotation( "GOC:tfm") "A fibroblast of the periodontium.") -AnnotationAssertion( ) -AnnotationAssertion( "2011-02-28T05:19:48Z") -AnnotationAssertion(rdfs:label "fibroblast of periodontium") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (fibroblast of pulmonary artery) - -AnnotationAssertion(Annotation( "GOC:tfm") "A fibroblast of pulmonary artery.") -AnnotationAssertion( ) -AnnotationAssertion( "2011-02-28T05:22:27Z") -AnnotationAssertion(rdfs:label "fibroblast of pulmonary artery") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (hair follicle cell) - -AnnotationAssertion(Annotation( "GOC:tfm") "An animal cell that is part of a hair follicle.") -AnnotationAssertion( ) -AnnotationAssertion( "2011-03-01T04:11:01Z") -AnnotationAssertion(rdfs:label "hair follicle cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf(Annotation( "true") ) - -# Class: (inner root sheath cell) - -AnnotationAssertion(Annotation( "GOC:tfm") "An epithelial cell that resides in the inner root sheath of the hair follicle.") -AnnotationAssertion( ) -AnnotationAssertion( "2011-03-01T04:27:51Z") -AnnotationAssertion(rdfs:label "inner root sheath cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) - -# Class: (outer root sheath cell) - -AnnotationAssertion(Annotation( "GOC:tfm") "An epithelial cell that is part of the outer root sheath.") -AnnotationAssertion( ) -AnnotationAssertion( "2011-03-01T04:29:47Z") -AnnotationAssertion(rdfs:label "outer root sheath cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) - -# Class: (hair germinal matrix cell) - -AnnotationAssertion(Annotation( "GOC:tfm") "An epidermal cell that is part of the germinal matrix.") -AnnotationAssertion( ) -AnnotationAssertion( "2011-03-01T04:31:06Z") -AnnotationAssertion( "trichocyte") -AnnotationAssertion(rdfs:label "hair germinal matrix cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (intestinal epithelial cell) - -AnnotationAssertion(Annotation( "GOC:tfm") "An epithelial cell of the intestine.") -AnnotationAssertion( ) -AnnotationAssertion( "2011-03-01T05:18:31Z") -AnnotationAssertion(rdfs:label "intestinal epithelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (nucleus pulposus cell of intervertebral disc) - -AnnotationAssertion(Annotation( "GOC:tfm") "A connective tissue cell of the nucleus pulposus cell of intervertebral disc.") -AnnotationAssertion( ) -AnnotationAssertion( "2011-03-02T02:12:23Z") -AnnotationAssertion(rdfs:label "nucleus pulposus cell of intervertebral disc") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (mesenchymal stem cell of umbilical cord) - -AnnotationAssertion(Annotation( "GOC:tfm") "A mesenchymal stem cell of the umbilical cord.") -AnnotationAssertion( ) -AnnotationAssertion( "2011-03-01T09:55:12Z") -AnnotationAssertion(rdfs:label "mesenchymal stem cell of umbilical cord") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (mesenchymal stem cell of adipose tissue) - -AnnotationAssertion(Annotation( "GOC:tfm") "A mesenchymal stem cell of adipose tissue.") -AnnotationAssertion( ) -AnnotationAssertion( "2011-03-01T09:57:17Z") -AnnotationAssertion( "mesenchymal stem cell of adipose") -AnnotationAssertion(rdfs:label "mesenchymal stem cell of adipose tissue") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (hepatic mesenchymal stem cell) - -AnnotationAssertion(Annotation( "GOC:tfm") "A mesenchymal stem cell of liver.") -AnnotationAssertion( ) -AnnotationAssertion( "2011-03-01T09:58:51Z") -AnnotationAssertion(rdfs:label "hepatic mesenchymal stem cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (vertebral mesenchymal stem cell) - -AnnotationAssertion(Annotation( "GOC:tfm") "A mesenchymal stem cell of the vertebrae.") -AnnotationAssertion( ) -AnnotationAssertion( "2011-03-01T10:40:27Z") -AnnotationAssertion(rdfs:label "vertebral mesenchymal stem cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) # Class: (Schwann cell) @@ -38525,213 +19062,6 @@ AnnotationAssertion(rdfs:label "Schw SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (stromal cell of pancreas) - -AnnotationAssertion(Annotation( "GOC:tfm") "A stromal cell of the pancreas.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "2011-03-02T02:40:41Z") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "stromal cell of pancreas") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (central nervous system pericyte) - -AnnotationAssertion(Annotation( "GOC:tfm") "A pericyte of the central nervous system.") -AnnotationAssertion( ) -AnnotationAssertion( "2011-03-02T02:54:18Z") -AnnotationAssertion(rdfs:label "central nervous system pericyte") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (placental epithelial cell) - -AnnotationAssertion(Annotation( "GOC:tfm") "An epithelial cell of the placenta.") -AnnotationAssertion( ) -AnnotationAssertion( "2011-03-02T03:21:30Z") -AnnotationAssertion(rdfs:label "placental epithelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) - -# Class: (mesenteric preadipocyte) - -AnnotationAssertion(Annotation( "GOC:tfm") "A preadipocyte found in mesenteric tissue.") -AnnotationAssertion( ) -AnnotationAssertion( "2011-03-03T04:19:40Z") -AnnotationAssertion(rdfs:label "mesenteric preadipocyte") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (omentum preadipocyte) - -AnnotationAssertion( ) -AnnotationAssertion( "2011-03-03T04:19:42Z") -AnnotationAssertion(rdfs:label "omentum preadipocyte") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (preadipocyte of the breast) - -AnnotationAssertion(Annotation( "GOC:tfm") "A preadipocyte that is part of the breast.") -AnnotationAssertion( ) -AnnotationAssertion( "2011-03-03T04:19:46Z") -AnnotationAssertion(rdfs:label "preadipocyte of the breast") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (perirenal preadipocyte) - -AnnotationAssertion( ) -AnnotationAssertion( "2011-03-03T04:20:04Z") -AnnotationAssertion(rdfs:label "perirenal preadipocyte") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (subcutaneous preadipocyte) - -AnnotationAssertion(Annotation( "GOC:tfm") "A preadipocyte that is part of subcutaneous tissue.") -AnnotationAssertion( ) -AnnotationAssertion( "2011-03-03T04:33:01Z") -AnnotationAssertion(rdfs:label "subcutaneous preadipocyte") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (renal cortical epithelial cell) - -AnnotationAssertion(Annotation( "GOC:tfm") "An epithelial cell of the kidney cortex.") -AnnotationAssertion( "KUPO:0001016") -AnnotationAssertion(rdfs:label "renal cortical epithelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) - -# Class: (retinal blood vessel endothelial cell) - -AnnotationAssertion(Annotation( "GOC:tfm") "A blood vessel endothelial cell that is part of the retina.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "2011-03-06T03:28:27Z") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "retinal blood vessel endothelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (retinal pigment epithelial cell) - -AnnotationAssertion(Annotation( "GOC:tfm") "An epithelial cell of the retinal pigmented epithelium.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "2011-03-06T03:37:09Z") -AnnotationAssertion( "BTO:0004910") -AnnotationAssertion( "FMA:75802") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "retinal pigment epithelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (smooth muscle cell of the umbilical vein) - -AnnotationAssertion(Annotation( "GOC:tfm") "A smooth muscle cell of the umbilical vein.") -AnnotationAssertion( ) -AnnotationAssertion( "2011-03-06T05:00:51Z") -AnnotationAssertion(rdfs:label "smooth muscle cell of the umbilical vein") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (smooth muscle cell of the brachiocephalic vasculature) - -AnnotationAssertion(Annotation( "GOC:tfm") "A smooth muscle cell of the bachiocephalic vasculature.") -AnnotationAssertion( ) -AnnotationAssertion( "2011-03-06T05:00:58Z") -AnnotationAssertion(rdfs:label "smooth muscle cell of the brachiocephalic vasculature") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (smooth muscle cell of the brain vasculature) - -AnnotationAssertion(Annotation( "GOC:tfm") "A vascular associated smooth muscle cell of the brain vasculature.") -AnnotationAssertion( ) -AnnotationAssertion( "2011-03-06T05:01:20Z") -AnnotationAssertion(rdfs:label "smooth muscle cell of the brain vasculature") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (smooth muscle cell of the pulmonary artery) - -AnnotationAssertion(Annotation( "GOC:tfm") "A smooth muscle of the pulmonary artery.") -AnnotationAssertion( ) -AnnotationAssertion( "2011-03-06T05:01:28Z") -AnnotationAssertion( "BTO:0003336") -AnnotationAssertion(rdfs:label "smooth muscle cell of the pulmonary artery") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (smooth muscle cell of the coronary artery) - -AnnotationAssertion(Annotation( "GOC:tfm") "A smooth muscle cell of the coronary artery.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "2011-03-06T05:01:34Z") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "smooth muscle cell of the coronary artery") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (smooth muscle cell of the internal thoracic artery) - -AnnotationAssertion(Annotation( "GOC:tfm") "A smooth muscle of the internal thoracic artery.") -AnnotationAssertion( ) -AnnotationAssertion( "2011-03-06T05:01:41Z") -AnnotationAssertion(rdfs:label "smooth muscle cell of the internal thoracic artery") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (smooth muscle cell of the umbilical artery) - -AnnotationAssertion(Annotation( "GOC:tfm") "A smooth muscle cell of the umbilical artery.") -AnnotationAssertion( ) -AnnotationAssertion( "2011-03-06T05:01:48Z") -AnnotationAssertion(rdfs:label "smooth muscle cell of the umbilical artery") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (smooth muscle cell of the subclavian artery) - -AnnotationAssertion(Annotation( "GOC:tfm") "A smooth muscle cell of the subclavian artery.") -AnnotationAssertion( ) -AnnotationAssertion( "2011-03-06T05:01:52Z") -AnnotationAssertion(rdfs:label "smooth muscle cell of the subclavian artery") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (smooth muscle cell of the carotid artery) - -AnnotationAssertion(Annotation( "GOC:tfm") "Smooth muscle cell of the carotid artery.") -AnnotationAssertion( ) -AnnotationAssertion( "2011-03-06T05:01:56Z") -AnnotationAssertion(rdfs:label "smooth muscle cell of the carotid artery") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (smooth muscle cell of bladder) - -AnnotationAssertion(Annotation( "GC:tfm") "A smooth muscle cell of the bladder.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "2011-03-06T05:43:24Z") -AnnotationAssertion( "KUPO:0001122") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "smooth muscle cell of bladder") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - # Class: (bronchial smooth muscle cell) AnnotationAssertion( ) @@ -38740,337 +19070,24 @@ AnnotationAssertion( AnnotationAssertion( "BTO:0004402") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "bronchial smooth muscle cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) -# Class: (smooth muscle cell of the esophagus) - -AnnotationAssertion(Annotation( "GOC:tfm") "A smooth muscle cell of the esophagus.") -AnnotationAssertion( ) -AnnotationAssertion( "2011-03-06T05:48:17Z") -AnnotationAssertion(rdfs:label "smooth muscle cell of the esophagus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (smooth muscle cell of trachea) - -AnnotationAssertion(Annotation( "GOC:tfm") "A smooth muscle cell of the trachea.") -AnnotationAssertion( ) -AnnotationAssertion( "2011-03-06T05:50:28Z") -AnnotationAssertion(rdfs:label "smooth muscle cell of trachea") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (uterine smooth muscle cell) - -AnnotationAssertion(Annotation( "GOC:tfm") "A smooth muscle cell of the uterus.") -AnnotationAssertion( ) -AnnotationAssertion( "2011-03-06T05:53:28Z") -AnnotationAssertion(rdfs:label "uterine smooth muscle cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (annulus pulposus cell) - -AnnotationAssertion( ) -AnnotationAssertion( "2011-03-06T06:50:53Z") -AnnotationAssertion( "anulus pulposus cell") -AnnotationAssertion(rdfs:label "annulus pulposus cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (astrocyte of the cerebellum) - -AnnotationAssertion(Annotation( "GOC:tfm") "An astrocyte of the cerebellum.") -AnnotationAssertion( ) -AnnotationAssertion( "2011-03-06T06:57:27Z") -AnnotationAssertion(rdfs:label "astrocyte of the cerebellum") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (hippocampal astrocyte) - -AnnotationAssertion(Annotation( "https://orcid.org/0000-0001-7258-9596") "An astrocyte that is part of the hippocampus.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "2011-03-06T06:57:33Z") -AnnotationAssertion( "astrocyte of the hippocampal formation") -AnnotationAssertion( "astrocyte of the hippocampus") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "hippocampal astrocyte") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (astrocyte of the cerebral cortex) - -AnnotationAssertion(Annotation( "GOC:tfm") "An astrocyte of the cerebral cortex.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "2011-03-06T06:57:36Z") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "astrocyte of the cerebral cortex") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (astrocyte of the spinal cord) - -AnnotationAssertion(Annotation( "GOC:tfm") "An astrocyte of the spinal cord.") -AnnotationAssertion( ) -AnnotationAssertion( "2011-03-06T07:11:26Z") -AnnotationAssertion(rdfs:label "astrocyte of the spinal cord") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (migratory enteric neural crest cell) - -AnnotationAssertion(Annotation( "GOC:tfm") "A neural crest cell that gives rise to cells of the enteric nervous system.") -AnnotationAssertion( ) -AnnotationAssertion( "2011-03-06T07:24:35Z") -AnnotationAssertion(rdfs:label "migratory enteric neural crest cell") -SubClassOf( ) - -# Class: (hippocampal neuron) - -AnnotationAssertion(Annotation( "GOC:tfm") "A neuron with a soma found in the hippocampus.") -AnnotationAssertion( ) -AnnotationAssertion( "2011-03-06T07:31:49Z") -AnnotationAssertion(rdfs:label "hippocampal neuron") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (raphe nuclei neuron) - -AnnotationAssertion(Annotation( "GOC:tfm") "A neuron of the raphe nuclei.") -AnnotationAssertion( ) -AnnotationAssertion( "2011-03-06T07:42:06Z") -AnnotationAssertion(rdfs:label "raphe nuclei neuron") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (neuron of the dorsal spinal cord) - -AnnotationAssertion(Annotation( "GOC:tfm") "A CNS neuron of the dorsal spinal cord.") -AnnotationAssertion( ) -AnnotationAssertion( "2011-03-06T07:43:34Z") -AnnotationAssertion(rdfs:label "neuron of the dorsal spinal cord") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (neuron of the ventral spinal cord) - -AnnotationAssertion(Annotation( "GOC:tfm") "A neuron of the ventral spinal cord.") -AnnotationAssertion( ) -AnnotationAssertion( "2011-03-06T07:46:03Z") -AnnotationAssertion(rdfs:label "neuron of the ventral spinal cord") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (striatum neuron) - -AnnotationAssertion(Annotation( "GOC:tfm") "A neuron of the striatum.") -AnnotationAssertion( ) -AnnotationAssertion( "2011-03-06T07:47:12Z") -AnnotationAssertion(rdfs:label "striatum neuron") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (neuron of the substantia nigra) - -AnnotationAssertion(Annotation( "GOC:tfm") "A neuron of the substantia nigra.") -AnnotationAssertion( ) -AnnotationAssertion( "2011-03-06T07:48:42Z") -AnnotationAssertion(rdfs:label "neuron of the substantia nigra") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (adipocyte of omentum tissue) - -AnnotationAssertion(Annotation( "GOC:tfm") "A fat cell that is part of omentum tissue.") -AnnotationAssertion( ) -AnnotationAssertion( "2011-03-14T10:17:00Z") -AnnotationAssertion( "omental adipocyte") -AnnotationAssertion( "omental fat cell") -AnnotationAssertion(rdfs:label "adipocyte of omentum tissue") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (perirenal adipocyte) - -AnnotationAssertion(Annotation( "GOC:tfm") "A fat cell of perirenal fat tissue.") -AnnotationAssertion( ) -AnnotationAssertion( "2011-03-14T10:17:05Z") -AnnotationAssertion( "perirenal adipocyte cell") -AnnotationAssertion( "perirenal fat cell") -AnnotationAssertion(rdfs:label "perirenal adipocyte") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (adipocyte of breast) - -AnnotationAssertion(Annotation( "GOC:tfm") "A fat cell that is part of the breast.") -AnnotationAssertion( ) -AnnotationAssertion( "2011-03-14T10:17:07Z") -AnnotationAssertion( "CALOHA:TS-2377") -AnnotationAssertion( "breast adipocyte") -AnnotationAssertion( "fat cell of breast") -AnnotationAssertion(rdfs:comment "Adipocytes found in the subcutaneous adipose tissue of breast. The breast consists of three main components, the skin, the subcutaneous adipose tissue and the functional glandular tissue that comprises both parenchyma and stroma.[CALOHA]") -AnnotationAssertion(rdfs:label "adipocyte of breast") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (endothelial cell of umbilical vein) - -AnnotationAssertion(Annotation( "GOC:tfm") "An endothelial cell of the umbilical vein.") -AnnotationAssertion( ) -AnnotationAssertion( "2011-03-14T11:36:51Z") -AnnotationAssertion( "BTO:0004296") -AnnotationAssertion(rdfs:label "endothelial cell of umbilical vein") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (skin fibroblast) - -AnnotationAssertion(Annotation( "GOC:tfm") "A fibroblast of skin.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "2011-03-14T12:31:49Z") -AnnotationAssertion( "BTO:0001255") -AnnotationAssertion( "CALOHA:TS-0935") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "skin fibroblast") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (gingival epithelial cell) - -AnnotationAssertion( ) -AnnotationAssertion( "2011-03-14T12:46:28Z") -AnnotationAssertion(rdfs:label "gingival epithelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) - -# Class: (prostate stromal cell) - -AnnotationAssertion(Annotation( "GOC:tfm") "A stromal cell of the prostate.") -AnnotationAssertion( ) -AnnotationAssertion( "2011-03-14T02:11:10Z") -AnnotationAssertion( "BTO:0003972") -AnnotationAssertion(rdfs:label "prostate stromal cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (acinar cell of salivary gland) - -AnnotationAssertion(Annotation( "GOC:tfm") "An acinar cell of salivary gland.") -AnnotationAssertion( ) -AnnotationAssertion( "2011-03-14T02:22:22Z") -AnnotationAssertion(rdfs:label "acinar cell of salivary gland") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - # Class: (seminiferous tubule epithelial cell) AnnotationAssertion(Annotation( "GOC:tfm") "A cell of the seminiferous tubule epithelium.") AnnotationAssertion( ) AnnotationAssertion( "2011-03-15T11:59:23Z") AnnotationAssertion(rdfs:label "seminiferous tubule epithelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (epithelial cell of upper respiratory tract) - -AnnotationAssertion( ) -AnnotationAssertion( "2011-06-21T12:28:55Z") -AnnotationAssertion(rdfs:label "epithelial cell of upper respiratory tract") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - # Class: (epithelial cell of lower respiratory tract) AnnotationAssertion( ) AnnotationAssertion( "2011-06-21T12:29:31Z") AnnotationAssertion(rdfs:label "epithelial cell of lower respiratory tract") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) -# Class: (epithelial cell of anal column) - -AnnotationAssertion(Annotation( "GOC:tfm") "An epithelial cell of the anal column.") -AnnotationAssertion( ) -AnnotationAssertion( "2011-07-08T12:11:38Z") -AnnotationAssertion(rdfs:label "epithelial cell of anal column") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) - -# Class: (keratinized epithelial cell of the anal canal) - -AnnotationAssertion(Annotation( "GOC:tfm") "An epithelial cell of the anal canal that is keratinized. This cell type is found towards the lower, rectal end of the anal canal.") -AnnotationAssertion( ) -AnnotationAssertion( "2011-07-08T02:08:40Z") -AnnotationAssertion(rdfs:label "keratinized epithelial cell of the anal canal") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (endothelial cell of venous sinus of spleen) - -AnnotationAssertion(Annotation( "GOC:tfm") "An endothelial cell that is part of the venous sinus of spleen. This endothelial cell has an elongated, spindle-shaped, flattened morphology that is parallel to long axis of sinus. This cell type rests on a basement membrane interrupted by numerous narrow slits.") -AnnotationAssertion( ) -AnnotationAssertion( "2011-07-08T03:06:49Z") -AnnotationAssertion( "FMA:72140") -AnnotationAssertion(Annotation( "FMA:62817") "stave cell") -AnnotationAssertion(rdfs:label "endothelial cell of venous sinus of spleen") -SubClassOf( ) - -# Class: (endothelial cell of high endothelial venule) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:20726857") "A venule endothelial cell that is cubodial, expresses leukocyte-specific receptors, and allows for passage of lymphocytes into bloodstream.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "2011-07-08T03:14:10Z") -AnnotationAssertion( "endothelial cell of postcapillary venule of lymph node") -AnnotationAssertion( "FMA:67759") -AnnotationAssertion( "HEV cell") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "Markers expressed on HEV include: MAdCAM-1,PNAd (sulfated and glycosylated molecules, i.e. GlyCAM-1, CD34, endomucin, nepmucin), ICAM-1, ICAM-2,Fuc-TVII, beta 3GlcNAcT-3, GlcNAc6ST2,CCL21, CCL19, CXCL13, CXCL12, Autotaxin, DARC, angiomodulin, LRHG.") -AnnotationAssertion(rdfs:label "endothelial cell of high endothelial venule") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (glandular cell of endometrium) - -AnnotationAssertion(Annotation( "GOC:tfm") "A glandular epithelial cell of the endometrium.") -AnnotationAssertion( ) -AnnotationAssertion( "2011-07-08T03:54:08Z") -AnnotationAssertion( "FMA:86489") -AnnotationAssertion(rdfs:label "glandular cell of endometrium") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (glandular cell of esophagus) - -AnnotationAssertion(Annotation( "GOC:tfm") "A glandular epithelial cell of the esophagus.") -AnnotationAssertion( ) -AnnotationAssertion( "2011-07-08T03:55:57Z") -AnnotationAssertion( "FMA:86548") -AnnotationAssertion(rdfs:label "glandular cell of esophagus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) - -# Class: (glandular cell of the large intestine) - -AnnotationAssertion(Annotation( "GOC:tfm") "A glandular epithelial cell of the large intestine.") -AnnotationAssertion( ) -AnnotationAssertion( "2011-07-08T04:03:01Z") -AnnotationAssertion( "FMA:87194") -AnnotationAssertion(rdfs:label "glandular cell of the large intestine") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - # Class: (glandular cell of stomach) AnnotationAssertion(Annotation( "GOC:tfm") "A glandular epithelial cell that is part of the stomach.") @@ -39079,30 +19096,8 @@ AnnotationAssertion( AnnotationAssertion( "CALOHA:TS-1284") AnnotationAssertion( "FMA:86554") AnnotationAssertion(rdfs:label "glandular cell of stomach") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) -# Class: (myocardial endocrine cell of atrium) - -AnnotationAssertion(Annotation( "GOC:tfm") "A myocardial endocrine cell that is part of the atrium.") -AnnotationAssertion( ) -AnnotationAssertion( "2011-07-11T02:45:39Z") -AnnotationAssertion( "FMA:83389") -AnnotationAssertion(rdfs:label "myocardial endocrine cell of atrium") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (cardioblast) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:19745164") "A stem cell that can give rise to multiple cell types (i.e. smooth muscle, endothelial) in the developing heart.") -AnnotationAssertion( ) -AnnotationAssertion( "2011-07-11T03:15:38Z") -AnnotationAssertion(Annotation( "PMID:17519333") Annotation( "PMID:19745164") "cardiovascular progenitor cell") -AnnotationAssertion(Annotation( "PMID:19745164") Annotation( ) "CPC") -AnnotationAssertion(rdfs:comment "Discrepancy in develops from origins prevents me from making the assertion that cardioblasts give rise to all instances of cardiocytes as we state cardiac muscle cells develop from cardiac myoblast, which in turn develop from muscle stem cell.") -AnnotationAssertion(rdfs:label "cardioblast") -SubClassOf( ) - # Class: (otic fibrocyte) AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:18353863") "A fibrocyte of the cochlea that has specialized structural and molecular adaptions.") @@ -39121,38 +19116,11 @@ AnnotationAssertion(rdfs:label "reti SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (tongue muscle cell) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:18816858") "A skeletal muscle cell that is part of the tongue.") -AnnotationAssertion( ) -AnnotationAssertion( "2011-08-16T03:10:02Z") -AnnotationAssertion(rdfs:label "tongue muscle cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (neural crest derived neuroblast) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:17407019") "A neuroblast derived from a neural crest cell.") -AnnotationAssertion( ) -AnnotationAssertion( "2011-08-22T09:24:15Z") -AnnotationAssertion(rdfs:label "neural crest derived neuroblast") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (PP cell of intestine) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:2420136") Annotation( "PMID:728970") "A PP cell found in intestine.") -AnnotationAssertion( ) -AnnotationAssertion( "2011-09-27T11:59:01Z") -AnnotationAssertion(rdfs:label "PP cell of intestine") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - # Class: (kidney cortical cell) AnnotationAssertion( ) AnnotationAssertion( "2011-10-25T03:49:41Z") AnnotationAssertion(rdfs:label "kidney cortical cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) # Class: (spinal cord interneuron) @@ -39160,7 +19128,6 @@ SubClassOf(Annotation( AnnotationAssertion(Annotation( "CL:CVS") "A CNS interneuron located in the spinal cord.") AnnotationAssertion(rdfs:comment "Is_a interneuron, part_of UBERON:0002240.") AnnotationAssertion(rdfs:label "spinal cord interneuron") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) # Class: (ionocyte) @@ -39168,14 +19135,6 @@ SubClassOf(Annotation( AnnotationAssertion(Annotation( "PMID:17555741") Annotation( "PMID:19268451") "Specialized epithelial cells involved in the maintenance of osmotic homeostasis. They are characterized by abundant mitochondria and ion transporters. In amniotes, they are present in the renal system. In freshwater fish, ionocytes in the skin and gills help maintain osmotic homeostasis by absorbing salt from the external environment.") AnnotationAssertion(rdfs:label "ionocyte") SubClassOf( ) -SubClassOf( ) - -# Class: (macular hair cell) - -AnnotationAssertion(Annotation( "GO:cvs") "An auditory hair cell located in the macula that is sensitive to auditory stimuli.") -AnnotationAssertion(rdfs:label "macular hair cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) # Class: (renal principal cell) @@ -39195,43 +19154,6 @@ AnnotationAssertion(rdfs:label "mult SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (auditory epithelial supporting cell) - -AnnotationAssertion(Annotation( "CL:CVS") Annotation( "GOC:tfm") "A non-sensory cell that extends from the basement membrane to the apical surface of the auditory epithelium and provides support for auditory hair cells.") -AnnotationAssertion( "auditory epithelial support cell") -AnnotationAssertion(rdfs:label "auditory epithelial supporting cell") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (lymphangioblast) - -AnnotationAssertion(Annotation( "CL:CVS") "Lymphatic progenitor cells.") -AnnotationAssertion( ) -AnnotationAssertion( "2012-01-12T04:44:34Z") -AnnotationAssertion(rdfs:comment "Usually express Prox1, or prox1b.") -AnnotationAssertion(rdfs:label "lymphangioblast") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (vascular lymphangioblast) - -AnnotationAssertion(Annotation( "CL:CVS") "Lymphatic progenitor cells, derived from the veins, that give rise to lymphatic endothelial cells.") -AnnotationAssertion( ) -AnnotationAssertion( "2012-01-12T05:21:09Z") -AnnotationAssertion( "parachordal lymphangioblast") -AnnotationAssertion(rdfs:label "vascular lymphangioblast") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (somatomotor neuron) - -AnnotationAssertion(Annotation( "ZFIN:CVS") "A motor neuron that innervates a skeletal muscle. These motor neurons are all excitatory and cholinergic.") -AnnotationAssertion( "somatic motor neuron") -AnnotationAssertion(rdfs:label "somatomotor neuron"@en) -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (hepatoblast) AnnotationAssertion(Annotation( "GOC:CVS") Annotation( "PMID:18356246") Annotation( "PMID:20483998") Annotation( "PMID:26798363") Annotation( "https://orcid.org/0000-0003-1940-6740") "Multi fate stem cell that gives rise to both hepatocytes and cholangiocytes as descendants. The term often refers to fetal precursors of hepatocytes (differently from 'hepatic stem cell', usually applied to the self-renewing pool of hepatocyte precursors in the adult liver). Hepatoblasts may also be endogenous, as some stem cells found in the liver come from the bone marrow via blood circulation.") @@ -39247,7 +19169,6 @@ AnnotationAssertion( AnnotationAssertion(rdfs:comment "unsure of neural crest contribution. In VSAO we have develops_from CL:0000008") AnnotationAssertion(rdfs:label "preameloblast") SubClassOf( ) -SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) @@ -39260,7 +19181,7 @@ AnnotationAssertion( AnnotationAssertion(Annotation( "GO_REF:0000034") "scleroblast") AnnotationAssertion(rdfs:comment "Needs logical definition. Should be capable_of skeletal system morphogenesis? or skeletal tissue development? needs to be added to GO. NOTES:a cell type of the early embryo (see also: mesenchymal cells) that will give rise to mineralized connective tissue. Scleroblasts can differentiate into osteoblasts (bone-forming cells), chondroblasts (cartilage-forming cells), odontoblasts (dentin-forming cells), ameloblasts (enamel-forming cells). The mesenchymal cells developing into osteoblasts and chondroblasts are derived from the mesoderm. Those developing into odontoblasts are neural crest cells. Those developing into ameloblasts are derived from the ectoderm. (http://www.copewithcytokines.de/cope.cgi?key=scleroblasts)") AnnotationAssertion(rdfs:label "skeletogenic cell") -SubClassOf( ) +SubClassOf( ) # Class: (precementoblast) @@ -39269,7 +19190,6 @@ AnnotationAssertion( "2012-06-15T04:37:13Z") AnnotationAssertion(rdfs:label "precementoblast") SubClassOf( ) -SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) # Class: (preodontoblast) @@ -39279,7 +19199,6 @@ AnnotationAssertion( "2012-06-15T05:15:11Z") AnnotationAssertion(rdfs:label "preodontoblast") SubClassOf( ) -SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) @@ -39300,7 +19219,6 @@ AnnotationAssertion( "2012-06-27T10:44:01Z") AnnotationAssertion(rdfs:label "prechondroblast") SubClassOf( ) -SubClassOf( ) # Class: (preosteoblast) @@ -39310,22 +19228,10 @@ AnnotationAssertion( AnnotationAssertion( "osteoprogenitor cell") AnnotationAssertion(rdfs:label "preosteoblast") SubClassOf( ) -SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (enteric neuron) - -AnnotationAssertion(Annotation( "CL:MAH") "Neuron that is part of the enteric nervous system.") -AnnotationAssertion( ) -AnnotationAssertion( "2012-06-28T08:20:31Z") -AnnotationAssertion(rdfs:label "enteric neuron") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (non-striated muscle cell) AnnotationAssertion(Annotation( "GOC:DOS") "Any muscle cell in which the fibers are not organised into sarcomeres.") @@ -39345,14 +19251,12 @@ SubClassOf( "GOC:tfm") Annotation( "ISBN:0323052908") "A transversely striated, synctial cell of skeletal muscle. It is formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.") AnnotationAssertion( "MESH:D018485") AnnotationAssertion(rdfs:label "skeletal muscle fiber"@en) -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf( ObjectSomeValuesFrom( )) # Class: (somatic muscle myotube) AnnotationAssertion(Annotation( "PMID:22274696") Annotation( "PMID:8720463") "A myotube that is part of some somatic muscle. Examples include arthropod somatic muscle cells.") AnnotationAssertion(rdfs:label "somatic muscle myotube") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) # Class: (somatic muscle cell) @@ -39365,7 +19269,6 @@ SubClassOf( "PMID:8720463") "A somatic muscle cell that is oblquely striated. Examples include the somatic muscles of nematodes.") AnnotationAssertion(rdfs:label "obliquely striated somatic muscle cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf( ) # Class: (visceral muscle cell) @@ -39373,106 +19276,16 @@ SubClassOf( "GOC:dos") "A muscle cell that is part of some visceral muscle.") AnnotationAssertion( "FBbt:00005070") AnnotationAssertion(rdfs:label "visceral muscle cell"@en) -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (striated visceral muscle cell) - -AnnotationAssertion(Annotation( "GOC:dos") "A visceral muscle cell that is striated. Examples include the visceral muscle cells of arhtropods.") -AnnotationAssertion(rdfs:label "striated visceral muscle cell"@en) -EquivalentClasses( ObjectIntersectionOf( ObjectIntersectionOf(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )))) - -# Class: (transversely striated visceral muscle cell) - -AnnotationAssertion(Annotation( "GOC:dos") "A visceral muscle that is transversely striated. Examples include the visceral muscle cells of arthropods.") -AnnotationAssertion(rdfs:label "transversely striated visceral muscle cell"@en) -EquivalentClasses( ObjectIntersectionOf( ObjectIntersectionOf(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )))) - -# Class: (adult skeletal muscle myoblast) - -AnnotationAssertion(Annotation( "PMID:23303905") "A skeletal muscle myoblast that is part of a skeletal mucle. These cells are formed following acivation and division of skeletal muscle satellite cells. They form a transient population that is lost when they fuse to form skeletal muscle fibers.") -AnnotationAssertion(Annotation( "PMID:23303905") "myogenic precursor cell") -AnnotationAssertion(rdfs:comment "The vast majority of these cells develop from skeletal muscle satellite cells, although there are some reports of other origins.") -AnnotationAssertion(rdfs:label "adult skeletal muscle myoblast") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (somatic muscle myoblast) - -AnnotationAssertion( "A myoblast that is commited to developing into a somatic muscle.") -AnnotationAssertion(rdfs:label "somatic muscle myoblast") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) # Class: (mesenchymal cell) AnnotationAssertion( "A non-polarised cell precursor cell that is part of some mesenchyme, is associated with the cell matrix but is not connected to other cells and is capable of migration.") AnnotationAssertion( "mesenchyme cell") AnnotationAssertion(rdfs:label "mesenchymal cell") -SubClassOf( ) -SubClassOf( ) +SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (anterior lateral line ganglion neuron) - -AnnotationAssertion(rdfs:label "anterior lateral line ganglion neuron") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (endocardial cushion cell) - -AnnotationAssertion(Annotation( "PMID:18816864") "A mesenchymal cell of the endocardial cushion. These cells develop via an epithelial to mesenchymal transition when endocardial cells break cell-to-cell contacts and migrate into the cardiac jelly. Cells from this population form the heart septa and valves.") -AnnotationAssertion(rdfs:label "endocardial cushion cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (pancreatic endocrine cell) - -AnnotationAssertion(Annotation( "GOC:dos") "An endocrine cell that is part of the pancreas.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "pancreatic endocrine cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (noradrenergic neuron) - -AnnotationAssertion(Annotation( "GOC:dos") "A neuron that release noradrenaline (noriphinephrine) as a neurotransmitter.") -AnnotationAssertion(rdfs:label "noradrenergic neuron") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (open tracheal system tracheocyte) - -AnnotationAssertion(Annotation( "GOC:dos") "An epithelial cell that is part of the epithelium of a tracheal tube in an open tracheal system, such as that found in insects.") -AnnotationAssertion( "FBbt:00005038") -AnnotationAssertion(rdfs:label "open tracheal system tracheocyte") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (visual system neuron) - -AnnotationAssertion( ) -AnnotationAssertion( "2017-07-09T19:12:36Z"^^xsd:dateTime) -AnnotationAssertion(rdfs:label "visual system neuron") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cortical interneuron) - -AnnotationAssertion( "An interneuron that has its soma located in the cerebral cortex.") -AnnotationAssertion( "cerebral cortex interneuron") -AnnotationAssertion(rdfs:label "cortical interneuron"@en) -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (decidual pericyte) - -AnnotationAssertion(Annotation( "PMID:30429548") "A pericyte of the decidual vasculature.") -AnnotationAssertion( ) -AnnotationAssertion( "2020-02-29T11:45:57Z"^^xsd:dateTime) -AnnotationAssertion( "decidual perivascular cell") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "decidual pericyte"@en) -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - # Class: (mural cell) AnnotationAssertion(Annotation( "Wiki:Mural_cell&oldid=930603194") "Mural cells are pericytes and the vascular smooth muscle cells (vSMCs) of the microcirculation.") @@ -39482,18 +19295,8 @@ AnnotationAssertion( AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "mural cell"@en) -SubClassOf( ) -SubClassOf( ) SubClassOf( ) -# Class: (microcirculation associated smooth muscle cell) - -AnnotationAssertion( ) -AnnotationAssertion( "2020-02-29T17:37:00Z"^^xsd:dateTime) -AnnotationAssertion(rdfs:label "microcirculation associated smooth muscle cell"@en) -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - # Class: (alpha motor neuron) AnnotationAssertion(Annotation( "DOI:10.1016/B978-0-12-801238-3.05364-2") Annotation( "Wikipedia:Alpha_motor_neuron&oldid=957148643") "A large, multipolar lower motor neuron of the brainstem and spinal cord that innervates the extrafusal muscle fibers of skeletal muscle and are directly responsible for initiating their contraction. While their cell bodies are in the CNS (in the anterior gray horn of the spinal cord), they are part of the somatic nervous system - a branch of the PNS.") @@ -39525,35 +19328,6 @@ AnnotationAssertion( "extrafusal muscle fiber"@en) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -DisjointClasses( ) - -# Class: (intrafusal muscle fiber) - -AnnotationAssertion(Annotation( "DOI:10.1016/B978-0-443-10321-6.00004-7") Annotation( "Wikipedia:Intrafusal_muscle_fiber&oldid=937508784") "A skeletal muscle fiber that is part of a muscle spindle. These are specialized muscle fibers that serve as proprioceptors, detecting the amount and rate of change in length of a muscle. They are innervated by both sensory neurons and motor neurons (gamma and beta motorneurons, collectively referred to as fusimotor neurons).") -AnnotationAssertion( ) -AnnotationAssertion( "2020-09-26T21:07:01Z"^^xsd:dateTime) -AnnotationAssertion( "TH:H3.03.00.0.00012") -AnnotationAssertion( "myofibra intrafusalis") -AnnotationAssertion(rdfs:label "intrafusal muscle fiber"@en) -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (sensory neuron of spinal nerve) - -AnnotationAssertion(Annotation( "GOC:nv") Annotation( "GOC:pr") "A sensory neuron of the spinal nerve that senses body position and sends information about how much the muscle is stretched to the spinal cord.") -AnnotationAssertion( "spinal sensory neuron") -AnnotationAssertion(rdfs:label "sensory neuron of spinal nerve") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (compound eye retinal cell) - -AnnotationAssertion( "Any cell in the compound eye, a light sensing organ composed of ommatidia.") -AnnotationAssertion( "GOC:pr") -AnnotationAssertion( "PMID:12021768") -AnnotationAssertion(rdfs:label "compound eye retinal cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))))) -SubClassOf( ) -SubClassOf( ) # Class: (retinal cell) @@ -39561,501 +19335,8 @@ AnnotationAssertion(Annotation( "PMID:10702418") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "retinal cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (enteroendocrine cell of small intestine) - -AnnotationAssertion(Annotation( "http://orcid.org/0000-0003-3440-1876") "An enteroendocrine cell that is located in the small intestine.") -AnnotationAssertion( ) -AnnotationAssertion( "small intestine enteroendocrine cell") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "enteroendocrine cell of small intestine") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (Peyer's patch lymphocyte) - -AnnotationAssertion(Annotation( "PMID:23525039") Annotation( "PMID:9252325") Annotation( "https://orcid.org/0000-0003-4183-8865") "A lymphocyte that is part of a Peyer's patch. These cells have a major role in driving the immune response to antigens sampled from the intestinal lumen, and in regulating the formation of follicle-associated epithelium and M cells in Peyer's patches by converting intestitial enterocytes into M cells.") -AnnotationAssertion( ) -AnnotationAssertion( "Peyer's patch resident lymphocyte") -AnnotationAssertion( "small intestine Peyer's patch lymphocyte") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "Peyer's patch lymphocyte") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (intestinal crypt stem cell of large intestine) - -AnnotationAssertion(Annotation( "PMID:20683682") Annotation( "https://orcid.org/0000-0003-4183-8865") "An intestinal stem cell that is located in the large intestine crypt of Liberkuhn. These stem cells reside at the bottom of crypts in the large intestine and are highly proliferative. They either differentiate into transit amplifying cells or self-renew to form new stem cells.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "crypt stem cell of large intestine") -AnnotationAssertion( "stem cell of large intestine crypt of Lieberkuhn") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "intestinal crypt stem cell of large intestine") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (intestinal crypt stem cell of small intestine) - -AnnotationAssertion(Annotation( "PMID:20683682") Annotation( "https://orcid.org/0000-0003-4183-8865") "An intestinal stem cell that is located in the small intestine crypt of Liberkuhn. These stem cells reside at the bottom of crypts in the small intestine and are highly proliferative. They either differentiate into transit amplifying cells or self-renew to form new stem cells.") -AnnotationAssertion( ) -AnnotationAssertion( "crypt stem cell of small intestine") -AnnotationAssertion( "stem cell of small intestine crypt of Lieberkuhn") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "intestinal crypt stem cell of small intestine") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (lymphocyte of large intestine lamina propria) - -AnnotationAssertion(Annotation( "https://orcid.org/0000-0003-4183-8865") "A lymphocyte that resides in the lamina propria of the large intestine.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "lamina propria lymphocyte of large intestine") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "This is a general grouping term created for use in the EMBL-EBI Single Cell Expression Atlas anatomograms. Please use a more specific cell type term for annotation if possible, given the information available to you.") -AnnotationAssertion(rdfs:label "lymphocyte of large intestine lamina propria") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (nephrogenic zone cell) - -AnnotationAssertion(Annotation( "PMID:29449449") Annotation( "https://orcid.org/0000-0002-3163-0115") "A kidney cortical cell that is part of the nephrogenic zone.") -AnnotationAssertion( ) -AnnotationAssertion( "cortical nephrogenic niche cell") -AnnotationAssertion( "cortical nephrogenic zone cell") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "nephrogenic zone cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (tuft cell of appendix) - -AnnotationAssertion(Annotation( "http://orcid.org/0000-0003-3440-1876") "An intestinal tuft cell that is a part of a vermiform appendix.") -AnnotationAssertion( ) -AnnotationAssertion( "appendix tuft cell") -AnnotationAssertion( "tuft cell of appendix vermiformis") -AnnotationAssertion( "tuft cell of vermiform appendix") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "tuft cell of appendix") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (stromal cell of lamina propria of large intestine) - -AnnotationAssertion(Annotation( "http://orcid.org/0000-0003-4183-8865") "A stromal cell found in the lamina propria of the large intestine.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "stromal cell of lamina propria of large intestine") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (stromal cell of lamina propria of small intestine) - -AnnotationAssertion(Annotation( "http://orcid.org/0000-0003-4183-8865") "A stromal cell found in the lamina propria of the small intestine.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "stromal cell of lamina propria of small intestine") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (mesothelial cell of small intestine) - -AnnotationAssertion(Annotation( "http://orcid.org/0000-0003-4183-8865") "A mesothelial cell that is part of the small intestine.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "mesothelial cell of small intestine") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (mesothelial cell of colon) - -AnnotationAssertion(Annotation( "http://orcid.org/0000-0003-3440-1876") Annotation( "http://orcid.org/0000-0003-4183-8865") "A mesothelial cell that is part of the colon.") -AnnotationAssertion( ) -AnnotationAssertion( "mesothelial cell of large intestine") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "mesothelial cell of colon") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (intestinal crypt stem cell of appendix) - -AnnotationAssertion(Annotation( "PMID:20683682") Annotation( "http://orcid.org/0000-0003-3440-1876") "An intestinal crypt stem cell that is located in the vermiform appendix. These stem cells reside at the bottom of crypts in the appendix and are highly proliferative. They either differentiate into transit amplifying cells or self-renew to form new stem cells.") -AnnotationAssertion( ) -AnnotationAssertion( "appendix intestinal crypt stem cell") -AnnotationAssertion( "intestinal crypt stem cell of appendix vermiformis") -AnnotationAssertion( "intestinal crypt stem cell of vermiform appendix") -AnnotationAssertion( "stem cell of intestinal crypt of Lieberkuhn of appendix") -AnnotationAssertion( "stem cell of intestinal crypt of Lieberkuhn of appendix vermiformis") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "intestinal crypt stem cell of appendix") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (mesothelial cell of appendix) - -AnnotationAssertion(Annotation( "http://orcid.org/0000-0003-3440-1876") "A mesothelial cell that is located in a vermiform appendix.") -AnnotationAssertion( ) -AnnotationAssertion( "appendix mesothelial cell") -AnnotationAssertion( "mesothelial cell of appendix vermiformis") -AnnotationAssertion( "mesothelial cell of vermiform appendix") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "mesothelial cell of appendix") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (enteroendocrine cell of appendix) - -AnnotationAssertion(Annotation( "http://orcid.org/0000-0003-3440-1876") "An intestinal enteroendocrine cell that is located in a vermiform appendix.") -AnnotationAssertion( ) -AnnotationAssertion( "appendix enteroendocrine cell") -AnnotationAssertion( "enteroendocrine cell of appendix vermiformis") -AnnotationAssertion( "enteroendocrine cell of vermiform appendix") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "enteroendocrine cell of appendix") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (T cell of appendix) - -AnnotationAssertion(Annotation( "http://orcid.org/0000-0003-3440-1876") "A T cell that is located in a vermiform appendix.") -AnnotationAssertion( ) -AnnotationAssertion( "T cell of appendix vermiformis") -AnnotationAssertion( "T cell of vermiform appendix") -AnnotationAssertion( "appendix T cell") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "This is a general grouping term created for use in the EMBL-EBI Single Cell Expression Atlas anatomograms. Please use a more specific cell type term for annotation if possible, given the information available to you.") -AnnotationAssertion(rdfs:label "T cell of appendix") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (B cell of appendix) - -AnnotationAssertion(Annotation( "http://orcid.org/0000-0003-3440-1876") "A B cell that is located in a vermiform appendix.") -AnnotationAssertion( ) -AnnotationAssertion( "B cell of appendix vermiformis") -AnnotationAssertion( "B cell of vermiform appendix") -AnnotationAssertion( "appendix B cell") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "This is a general grouping term created for use in the EMBL-EBI Single Cell Expression Atlas anatomograms. Please use a more specific cell type term for annotation if possible, given the information available to you.") -AnnotationAssertion(rdfs:label "B cell of appendix") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (plasma cell of appendix) - -AnnotationAssertion(Annotation( "http://orcid.org/0000-0003-3440-1876") "A plasma cell that is located in a vermiform appendix.") -AnnotationAssertion( ) -AnnotationAssertion( "appendix plasma cell") -AnnotationAssertion( "plasma cell of appendix vermiformis") -AnnotationAssertion( "plasma cell of vermiform appendix") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "This is a general grouping term created for use in the EMBL-EBI Single Cell Expression Atlas anatomograms. Please use a more specific cell type term for annotation if possible, given the information available to you.") -AnnotationAssertion(rdfs:label "plasma cell of appendix") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (dendritic cell of appendix) - -AnnotationAssertion(Annotation( "http://orcid.org/0000-0003-3440-1876") "A dendritic cell that is located in a vermiform appendix.") -AnnotationAssertion( ) -AnnotationAssertion( "appendix dendritic cell") -AnnotationAssertion( "dendritic cell of appendix vermiformis") -AnnotationAssertion( "dendritic cell of vermiform appendix") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "This is a general grouping term created for use in the EMBL-EBI Single Cell Expression Atlas anatomograms. Please use a more specific cell type term for annotation if possible, given the information available to you.") -AnnotationAssertion(rdfs:label "dendritic cell of appendix") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (stromal cell of lamina propria of vermiform appendix) - -AnnotationAssertion(Annotation( "http://orcid.org/0000-0003-3440-1876") "A stromal cell found in the lamina propria of the vermiform appendix.") -AnnotationAssertion( ) -AnnotationAssertion( "stromal cell of appendix lamina propria") -AnnotationAssertion( "stromal cell of lamina propria of appendix vermiformis") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "stromal cell of lamina propria of vermiform appendix") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (appendix macrophage) - -AnnotationAssertion(Annotation( "http://orcid.org/0000-0003-3440-1876") "A macrophage located in the vermiform appendix.") -AnnotationAssertion( ) -AnnotationAssertion( "macrophage of appendix") -AnnotationAssertion( "macrophage of appendix vermiformis") -AnnotationAssertion( "macrophage of vermiform appendix") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "This is a general grouping term created for use in the EMBL-EBI Single Cell Expression Atlas anatomograms. Please use a more specific cell type term for annotation if possible, given the information available to you.") -AnnotationAssertion(rdfs:label "appendix macrophage") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (lymph node mantle zone B cell) - -AnnotationAssertion(Annotation( "PMID:8011279") Annotation( "http://orcid.org/0000-0003-4183-8865/") Annotation( "https://www.arppress.org/v/vspfiles/assets/images/Chapter1T25LymphNodes.pdf") "A B lymphocyte that resides in the mantle zone of the lymph node germinal center. These are generally IgM and IgD positive activated B cells that form a 'corona' around the germinal center and are part of the establishment of a secondary lymphatic follicule.") -AnnotationAssertion( ) -AnnotationAssertion( "mantle zone B cell") -AnnotationAssertion( "mantle zone B cell of lymph node") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "This is a general grouping term created for use in the EMBL-EBI Single Cell Expression Atlas anatomograms. Please use a more specific cell type term for annotation if possible, given the information available to you.") -AnnotationAssertion(rdfs:label "lymph node mantle zone B cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (colon macrophage) - -AnnotationAssertion(Annotation( "http://orcid.org/0000-0003-3440-1876") "A macrophage that is located in the colon.") -AnnotationAssertion( ) -AnnotationAssertion( "macrophage of colon") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "This is a general grouping term created for use in the EMBL-EBI Single Cell Expression Atlas anatomograms. Please use a more specific cell type term for annotation if possible, given the information available to you.") -AnnotationAssertion(rdfs:label "colon macrophage") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (colon goblet cell) - -AnnotationAssertion(Annotation( "http://orcid.org/0000-0003-3440-1876") "A goblet cell that is located in the colon.") -AnnotationAssertion( ) -AnnotationAssertion( "goblet cell of colon") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "colon goblet cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (stromal cell of lamina propria of colon) - -AnnotationAssertion(Annotation( "http://orcid.org/0000-0003-3440-1876") "A stromal cell found in the lamina propria of the colon.") -AnnotationAssertion( ) -AnnotationAssertion( "stromal cell of colon lamina propria") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "stromal cell of lamina propria of colon") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (tuft cell of colon) - -AnnotationAssertion(Annotation( "http://orcid.org/0000-0003-3440-1876") "A tuft cell that is a part of the colon.") -AnnotationAssertion( ) -AnnotationAssertion( "colon tuft cell") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "tuft cell of colon") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (enteroendocrine cell of colon) - -AnnotationAssertion(Annotation( "http://orcid.org/0000-0003-3440-1876") "An enteroendocrine cell that is located in the colon.") -AnnotationAssertion( ) -AnnotationAssertion( "colon enteroendocrine cell") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "enteroendocrine cell of colon") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (intestinal crypt stem cell of colon) - -AnnotationAssertion(Annotation( "http://orcid.org/0000-0003-3440-1876") "An intestinal crypt stem cell that is located in the colon.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "intestinal crypt stem cell of colon") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (lymphocyte of small intestine lamina propria) - -AnnotationAssertion(Annotation( "PMID:26551552") Annotation( "https://orcid.org/0000-0003-4183-8865") "A lymphocyte that resides in the lamina propria of the small intestine. Lamina propria leukocytes and intraepithelial lymphocytes are the effector compartments of the gut mucosal immune system. Lymphocytes circulate through gut associated lymphoid tissues until recruitment by intestinal antigens. They are involved in the gut immune response.") -AnnotationAssertion( ) -AnnotationAssertion( "gastrointestinal tract small intestine (lamina propria) leukocyte") -AnnotationAssertion( "small intestine lamina propria leukocyte") -AnnotationAssertion( "small intestine lamina propria leukocyte (LPL)") -AnnotationAssertion( "gastrointestinal tract (lamina propria) lymphocyte of small intestine") -AnnotationAssertion( "lamina propria lymphocyte of small intestine") -AnnotationAssertion( "small intestine lamina propria lymphocyte") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "This is a general grouping term created for use in the EMBL-EBI Single Cell Expression Atlas anatomograms. Please use a more specific cell type term for annotation if possible, given the information available to you.") -AnnotationAssertion(rdfs:label "lymphocyte of small intestine lamina propria") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (B cell of medullary sinus of lymph node) - -AnnotationAssertion(Annotation( "http://orcid.org/0000-0003-4183-8865") "A B cell found in the lymph node medullary sinus.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "This is a general grouping term created for use in the EMBL-EBI Single Cell Expression Atlas anatomograms. Please use a more specific cell type term for annotation if possible, given the information available to you.") -AnnotationAssertion(rdfs:label "B cell of medullary sinus of lymph node") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (T cell of medullary sinus of lymph node) - -AnnotationAssertion(Annotation( "http://orcid.org/0000-0003-4183-8865") "A T cell found in the lymph node medullary sinus.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "This is a general grouping term created for use in the EMBL-EBI Single Cell Expression Atlas anatomograms. Please use a more specific cell type term for annotation if possible, given the information available to you.") -AnnotationAssertion(rdfs:label "T cell of medullary sinus of lymph node") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (macrophage of medullary sinus of lymph node) - -AnnotationAssertion(Annotation( "http://orcid.org/0000-0003-4183-8865") "A macrophage found in the medullary sinus of the lymph node.") -AnnotationAssertion( ) -AnnotationAssertion( "medullary sinus macrophage") -AnnotationAssertion( "lymph node medullary sinus macrophage") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "This is a general grouping term created for use in the EMBL-EBI Single Cell Expression Atlas anatomograms. Please use a more specific cell type term for annotation if possible, given the information available to you.") -AnnotationAssertion(rdfs:label "macrophage of medullary sinus of lymph node") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (anorectum macrophage) - -AnnotationAssertion(Annotation( "http://orcid.org/0000-0003-3440-1876") "A macrophage that is located in the anorectum.") -AnnotationAssertion( ) -AnnotationAssertion( "macrophage of anorectum") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "This is a general grouping term created for use in the EMBL-EBI Single Cell Expression Atlas anatomograms. Please use a more specific cell type term for annotation if possible, given the information available to you.") -AnnotationAssertion(rdfs:label "anorectum macrophage") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (smooth muscle cell of high endothelial venule of lymph node) - -AnnotationAssertion(Annotation( "PMID:27881983") Annotation( "http://orcid.org/0000-0003-4183-8865") "A layer of smooth muscle cells that forms the outer layer of the high endothelial venule of lymph node and pumps to allow flow of lymph fluid carrying lymphocytes.") -AnnotationAssertion( ) -AnnotationAssertion( "high endothelial venule smooth muscle cell") -AnnotationAssertion( "high endothelial venule of lymph node smooth muscle cell") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "smooth muscle cell of high endothelial venule of lymph node") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (B cell of anorectum) - -AnnotationAssertion(Annotation( "http://orcid.org/0000-0003-3440-1876") "A B cell that is located in the anorectum.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "This is a general grouping term created for use in the EMBL-EBI Single Cell Expression Atlas anatomograms. Please use a more specific cell type term for annotation if possible, given the information available to you.") -AnnotationAssertion(rdfs:label "B cell of anorectum") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (T cell of anorectum) - -AnnotationAssertion(Annotation( "http://orcid.org/0000-0003-3440-1876") "A T cell that is located in the anorectum.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "This is a general grouping term created for use in the EMBL-EBI Single Cell Expression Atlas anatomograms. Please use a more specific cell type term for annotation if possible, given the information available to you.") -AnnotationAssertion(rdfs:label "T cell of anorectum") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (smooth muscle cell of anorectum) - -AnnotationAssertion(Annotation( "http://orcid.org/0000-0003-3440-1876") "A smooth muscle cell that is located in the anorectum.") -AnnotationAssertion( ) -AnnotationAssertion( "anorectum smooth muscle cell") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "smooth muscle cell of anorectum") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (stromal cell of anorectum lamina propria) - -AnnotationAssertion(Annotation( "http://orcid.org/0000-0003-3440-1876") "A stromal cell found in the lamina propria of the anorectum.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "stromal cell of anorectum lamina propria") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (anorectum goblet cell) - -AnnotationAssertion(Annotation( "http://orcid.org/0000-0003-3440-1876") "A goblet cell that is located in the anorectum.") -AnnotationAssertion( ) -AnnotationAssertion( "goblet cell of anorectum") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "anorectum goblet cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (plasma cell of medullary sinus of lymph node) - -AnnotationAssertion(Annotation( "http://orcid.org/0000-0003-4183-8865") "A plasma cell that is located in the medullary sinus of the lymph node.") -AnnotationAssertion( ) -AnnotationAssertion( "medullary plasma cell") -AnnotationAssertion( "medullary sinus plasma cell") -AnnotationAssertion( "plasma cell of medullary sinus") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "This is a general grouping term created for use in the EMBL-EBI Single Cell Expression Atlas anatomograms. Please use a more specific cell type term for annotation if possible, given the information available to you.") -AnnotationAssertion(rdfs:label "plasma cell of medullary sinus of lymph node") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (marginal zone B cell of lymph node) - -AnnotationAssertion(Annotation( "WikipediaVersioned:Marginal_zone_B-cell&oldid=1032071222") Annotation( "http://orcid.org/0000-0003-4183-8865") "A mature B cell located in the marginal zone of the lymph node.") -AnnotationAssertion( ) -AnnotationAssertion( "marginal zone B cell") -AnnotationAssertion( "lymph node marginal zone B cell") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "marginal zone B cell of lymph node") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (intestinal crypt stem cell of anorectum) - -AnnotationAssertion(Annotation( "http://orcid.org/0000-0003-3440-1876") "An intestinal crypt stem cell that is located in the anorectum.") -AnnotationAssertion( ) -AnnotationAssertion( "anorectum intestinal crypt stem cell") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "intestinal crypt stem cell of anorectum") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (enteroendocrine cell of anorectum) - -AnnotationAssertion(Annotation( "http://orcid.org/0000-0003-3440-1876") "An enteroendocrine cell that is located in the anorectum.") -AnnotationAssertion( ) -AnnotationAssertion( "anorectum enteroendocrine cell") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "enteroendocrine cell of anorectum") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (lymph node paracortex T cell) - -AnnotationAssertion(Annotation( "http://orcid.org/0000-0003-4183-8865") "A T cell located in the lymph node paracortex, where macrophages and dendritic cells present antigenic peptides to these naïve T cells, stimulating them to become activated helper T cells or cytotoxic T lymphocytes.") -AnnotationAssertion( ) -AnnotationAssertion( "paracortex T cell") -AnnotationAssertion( "paracortical T cell") -AnnotationAssertion( "T cell of lymph node paracortex") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "lymph node paracortex T cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (tuft cell of anorectum) - -AnnotationAssertion(Annotation( "http://orcid.org/0000-0003-3440-1876") "An intestinal tuft cell that is located in the anorectum.") -AnnotationAssertion( ) -AnnotationAssertion( "anorectum tuft cell") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "tuft cell of anorectum") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (stratified squamous epithelial cell of anal canal) - -AnnotationAssertion(Annotation( "http://orcid.org/0000-0003-3440-1876") "A stratified squamous epithelial cell that is part of the anal canal.") -AnnotationAssertion( ) -AnnotationAssertion( "anal canal stratified squamous epithelial cell") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "This is a general grouping term created for use in the EMBL-EBI Single Cell Expression Atlas anatomograms. Please use a more specific cell type term for annotation if possible, given the information available to you.") -AnnotationAssertion(rdfs:label "stratified squamous epithelial cell of anal canal") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (tuft cell of small intestine) - -AnnotationAssertion(Annotation( "http://orcid.org/0000-0003-3440-1876") Annotation( "http://orcid.org/0000-0003-4183-8865") "A tuft cell located in the small intestine.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "brush cell of epithelium of small intestine") -AnnotationAssertion( "brush cell of epithelium proper of small intestine") -AnnotationAssertion( "brush cell of small intestine") -AnnotationAssertion( "tuft cell of epithelium of small intestine") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "tuft cell of small intestine") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (epithelial cell of endometrial gland) - -AnnotationAssertion(Annotation( "https://orcid.org/0000-0003-3440-1876") Annotation( "https://orcid.org/0000-0003-4183-8865") "An epithelial cell that is part of an endometrial gland.") -AnnotationAssertion( ) -AnnotationAssertion( "2021-11-30T16:13:30Z"^^xsd:dateTime) -AnnotationAssertion( "EFO:0010710") -AnnotationAssertion( "endometrial glandular epithelial cell") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "epithelial cell of endometrial gland") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (endothelial cell of respiratory system lymphatic vessel) - -AnnotationAssertion(Annotation( "https://orcid.org/0000-0003-3440-1876") Annotation( "https://orcid.org/0000-0003-4183-8865") "An endothelial cell that is part of a respiratory system lymphatic vessel.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "2021-12-03T14:00:44Z"^^xsd:dateTime) -AnnotationAssertion( "EFO:0010667") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "endothelial cell of respiratory system lymphatic vessel") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (lung pericyte) AnnotationAssertion(Annotation( "https://orcid.org/0000-0003-3440-1876") Annotation( "https://orcid.org/0000-0003-4183-8865") "A pericyte cell that is part of a lung.") @@ -40068,7 +19349,6 @@ AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "lung pericyte") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (Leydig stem cell) @@ -40080,173 +19360,10 @@ AnnotationAssertion(rdfs:label "Leyd SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (endothelial cell of placenta) - -AnnotationAssertion(Annotation( "https://orcid.org/0000-0003-3440-1876") Annotation( "https://orcid.org/0000-0003-4183-8865") "An endothelial cell that is part of a placenta.") -AnnotationAssertion( ) -AnnotationAssertion( "2021-12-13T13:53:01Z"^^xsd:dateTime) -AnnotationAssertion( "EFO:0010708") -AnnotationAssertion( "placental endothelial cell") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "endothelial cell of placenta") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (smooth muscle cell of placenta) - -AnnotationAssertion(Annotation( "https://orcid.org/0000-0003-3440-1876") Annotation( "https://orcid.org/0000-0003-4183-8865") "A smooth muscle cell that is part of a placenta.") -AnnotationAssertion( ) -AnnotationAssertion( "2021-12-13T13:56:42Z"^^xsd:dateTime) -AnnotationAssertion( "EFO:0010709") -AnnotationAssertion( "placental smooth muscle cell") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "smooth muscle cell of placenta") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (endothelial cell of hepatic portal vein) - -AnnotationAssertion(Annotation( "PMID:30348985") Annotation( "https://orcid.org/0000-0003-3440-1876") Annotation( "https://orcid.org/0000-0003-4183-8865") "An endothelial cell that is part of a hepatic portal vein.") -AnnotationAssertion( ) -AnnotationAssertion( "2021-12-13T14:01:05Z"^^xsd:dateTime) -AnnotationAssertion( "portal endothelial cell") -AnnotationAssertion( "EFO:0010704") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "endothelial cell of hepatic portal vein") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (endothelial cell of uterus) - -AnnotationAssertion(Annotation( "https://orcid.org/0000-0003-3440-1876") Annotation( "https://orcid.org/0000-0003-4183-8865") "An endothelial cell that is part of a uterus.") -AnnotationAssertion( ) -AnnotationAssertion( "2021-12-13T14:39:25Z"^^xsd:dateTime) -AnnotationAssertion( "EFO:0010711") -AnnotationAssertion( "uterine endothelial cell") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "endothelial cell of uterus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (embryonic skeletal muscle fiber) - -AnnotationAssertion(Annotation( "PMID:32094117") Annotation( "PMID:7196501") Annotation( "http://orcid.org/0000-0003-2034-601X") "A skeletal muscle fiber found in an embryo. In mammalian embryos, skeletal muscle expresses myosin heavy chain-embryonic (MyHC-emb, encoded by the MYH3 gene), which regulates skeletal muscle development.") -AnnotationAssertion( ) -AnnotationAssertion( "2022-02-21T15:39:10Z"^^xsd:dateTime) -AnnotationAssertion(rdfs:label "embryonic skeletal muscle fiber") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (fetal and neonatal skeletal muscle fiber) - -AnnotationAssertion(Annotation( "PMID:26180627") Annotation( "PMID:7196501") Annotation( "http://orcid.org/0000-0003-2034-601X") "A skeletal muscle fiber found at the fetal and neonatal stages. In mammalian fetuses and neonates, skeletal muscle expresses myosin heavy chain-neonatal (MyHC-neo, encoded by the MYH8 gene). This expression disappears shortly after birth and is replaced by expression of adult heavy chain myosins.") -AnnotationAssertion( ) -AnnotationAssertion( "2022-02-21T15:43:16Z"^^xsd:dateTime) -AnnotationAssertion(rdfs:label "fetal and neonatal skeletal muscle fiber") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (hepatic portal fibroblast) - -AnnotationAssertion(Annotation( "PMID:20209607") Annotation( "PMID:24814904") Annotation( "https://orcid.org/0000-0001-7655-4833") "A fibroblast located in the portal triad. Hepatic portal fibroblast are a non-parenchymal cell population located adjacent to bile duct epithelia in liver and are distinct from stellate cells. They differentiate into fibrogenic myofibroblasts during chronic injury states producing high levels of collagen.") -AnnotationAssertion( ) -AnnotationAssertion( "2022-03-17T12:00:44Z"^^xsd:dateTime) -AnnotationAssertion( "portal fibroblast") -AnnotationAssertion(rdfs:label "hepatic portal fibroblast") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (lymph node lymphatic vessel endothelial cell) - -AnnotationAssertion(Annotation( "https://orcid.org/0000-0001-7655-4833") "An endothelial cell located in a lymph node lymphatic vessel.") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "lymph node lymphatic vessel endothelial cell") -AnnotationAssertion(rdfs:seeAlso "https://github.com/obophenotype/cell-ontology/issues/1472") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (stromal cell of bone marrow) - -AnnotationAssertion( "A stromal cell that is part_of a bone marrow.") -AnnotationAssertion( ) -AnnotationAssertion( "bone marrow stromal cell") -AnnotationAssertion(rdfs:label "stromal cell of bone marrow") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (epithelial cell of umbilical artery) - -AnnotationAssertion( "An epithelial cell that is part_of a umbilical artery.") -AnnotationAssertion( ) -AnnotationAssertion( "umbilical artery epithelial cell") -AnnotationAssertion(rdfs:label "epithelial cell of umbilical artery") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (epithelial cell of alveolus of lung) - -AnnotationAssertion( "An epithelial cell that is part_of a alveolus of lung.") -AnnotationAssertion( ) -AnnotationAssertion( "MESH:D056809") -AnnotationAssertion( "alveolus of lung epithelial cell") -AnnotationAssertion(rdfs:comment "May be merged with pneumocyte in future") -AnnotationAssertion(rdfs:label "epithelial cell of alveolus of lung") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (mononuclear cell of bone marrow) - -AnnotationAssertion( "A mononuclear cell that is part_of a bone marrow.") -AnnotationAssertion( ) -AnnotationAssertion( "bone marrow mononuclear cell") -AnnotationAssertion(rdfs:label "mononuclear cell of bone marrow") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (atrioventricular bundle cell) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "A specialized cardiomyocyte that transmit signals from the AV node to the cardiac Purkinje fibers.") -AnnotationAssertion( "AV bundle cell") -AnnotationAssertion(rdfs:label "atrioventricular bundle cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (cardiac blood vessel endothelial cell) - -AnnotationAssertion(rdfs:label "cardiac blood vessel endothelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (His-Purkinje system cell) - -AnnotationAssertion(rdfs:label "His-Purkinje system cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (cardiac endothelial cell) - -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "cardiac endothelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (camera-type eye photoreceptor cell) AnnotationAssertion( "camera type eye photoreceptor cell") AnnotationAssertion(rdfs:label "camera-type eye photoreceptor cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cerebellar stellate cell) - -AnnotationAssertion(rdfs:label "cerebellar stellate cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cerebral cortex GABAergic interneuron) - -AnnotationAssertion(Annotation( "GOC:dos") "A GABAergic interneuron whose soma is located in the cerebral cortex.") -AnnotationAssertion(rdfs:label "cerebral cortex GABAergic interneuron") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cerebral cortex neuron) - -AnnotationAssertion(Annotation( "GOC:tfm") "A CNS neuron of the cerebral cortex.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "BTO:0004102") -AnnotationAssertion( "FMA:84104") -AnnotationAssertion( "cortical neuron") -AnnotationAssertion( "neuron of cerebral cortex") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "cerebral cortex neuron") -AnnotationAssertion(rdfs:seeAlso "https://github.com/obophenotype/cell-ontology/issues/1359") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (coronet cell) @@ -40261,42 +19378,7 @@ AnnotationAssertion( "MESH:D015053") AnnotationAssertion(rdfs:label "zygote"@en) AnnotationAssertion(rdfs:seeAlso ) -SubClassOf( ) - -# Class: (cardiac glial cell) - -AnnotationAssertion(rdfs:label "cardiac glial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cardiac myoblast) - -AnnotationAssertion( "MESH:D032386") -AnnotationAssertion(rdfs:label "cardiac myoblast") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (cardiac neuron) - -AnnotationAssertion(Annotation( "PMID:12486170") Annotation( "PMID:29265764") "A neuron that has its soma in the heart.") -AnnotationAssertion(rdfs:comment "This term is used in 3 GO terms that were created as part of the heart development focus project.") -AnnotationAssertion(rdfs:label "cardiac neuron") -AnnotationAssertion(rdfs:seeAlso "https://github.com/obophenotype/cell-ontology/pull/1488") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (dorsal horn interneuron) - -AnnotationAssertion(Annotation( "GOC:nv") "A CNS interneuron located in the dorsal horn of the spinal cord.") -AnnotationAssertion( "dorsal spinal cord interneuron") -AnnotationAssertion(rdfs:label "dorsal horn interneuron") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (spinal cord motor neuron) - -AnnotationAssertion(Annotation( "GOC:nv") "A motor neuron that passes from the spinal cord toward or to a muscle and conducts an impulse that causes movement.") -AnnotationAssertion(rdfs:label "spinal cord motor neuron") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) +SubClassOf( ) # Class: (magnocellular neurosecretory cell) @@ -40327,19 +19409,8 @@ AnnotationAssertion( ) AnnotationAssertion(rdfs:comment "The formal and textual definitions of this term will need to be altered if evidence for non-inhibitory GABA-ergic neurons emerges.") AnnotationAssertion(rdfs:label "GABAergic interneuron") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (paraxial cell) - -AnnotationAssertion(Annotation( "GOC:NV") Annotation( "PMID:11687492") "A cell in the area of mesoderm in the neurulating embryo that flanks and forms simultaneously with the neural tube. The cells of this region give rise to somites.") -AnnotationAssertion( "paraxial mesoderm cell") -AnnotationAssertion( "somitic mesoderm cell") -AnnotationAssertion( "presomitic mesoderm cell") -AnnotationAssertion(rdfs:label "paraxial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - # Class: (neural crest cell) AnnotationAssertion(Annotation( "https://orcid.org/0000-0001-5208-3432") Annotation( "https://orcid.org/0000-0002-9900-7880") "A cell of the neural crest. Neural crest cells are multipotent. Premigratory neural crest cells are found at the neural plate boarder, some of which will undergo ectomesynchymal transition and delamination to form migratory neural crest cells.") @@ -40347,81 +19418,13 @@ AnnotationAssertion(rdfs:label "neur SubClassOf( ) SubClassOf( ) -# Class: (motile sperm cell) - -AnnotationAssertion(Annotation( "PMID:30612620") "A sperm cell that is cabaple of motion (motility).") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "motile sperm cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (flagellated sperm cell) - -AnnotationAssertion(Annotation( "PMID:30612620") Annotation( "https://www.lexico.com/en/definition/flagellum") "A motile sperm cell that contains a slender threadlike microscopic appendage that enables motion.") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "flagellated sperm cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (mesothelial cell of epicardium) - -AnnotationAssertion( "A mesothelial cell that is part of the epicardium.") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "mesothelial cell of epicardium") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (fibroblast of upper back skin) - -AnnotationAssertion( "A fibroblast that is part of upper back skin.") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "fibroblast of upper back skin") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (fibroblast of skin of back) - -AnnotationAssertion( "A fibroblast that is part of skin of back.") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "fibroblast of skin of back") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - # Class: (progenitor cell) AnnotationAssertion(Annotation( "ISBN:978-1-62808-994-3") Annotation( "https://doi.org/10.1016/B978-0-12-409503-8.00002-0") "A precursor cell that has a tendency to differentiate into a specific type of cell. They are descendants of stem cells, only they are more constrained in their differentiation potential or capacity for self-renewal, and are often more limited in both senses.") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "progenitor cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (skeletal muscle fibroblast) - -AnnotationAssertion(Annotation( "PMID:28369879") Annotation( "https://orcid.org/0000-0001-6164-0667") "Any fibroblast that is part of skeletal muscle tissue.") -AnnotationAssertion( ) -AnnotationAssertion( "skeleton muscle fibroblast") -AnnotationAssertion(rdfs:label "skeletal muscle fibroblast") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (dermal microvascular endothelial cell) - -AnnotationAssertion(Annotation( "BTO:0004574") Annotation( "CL:patterns/cellPartOfAnatomicalEntity") "Any microvascular endothelial cell that is part of the dermis.") -AnnotationAssertion( ) -AnnotationAssertion( "DMEC cell") -AnnotationAssertion( "dermal microvascular endothelium cell") -AnnotationAssertion(rdfs:label "dermal microvascular endothelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (chorionic trophoblast cell) - -AnnotationAssertion(Annotation( "GOC:NV") "Cells of the uterine chorion that acquire specialized structural and/or functional features that characterize chorionic trophoblasts. These cells will migrate towards the spongiotrophoblast layer and give rise to syncytiotrophoblasts of the labyrinthine layer.") -AnnotationAssertion(rdfs:label "chorionic trophoblast cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - # Class: (sympathetic neuron) AnnotationAssertion(Annotation( "GOC:NV") Annotation( "isbn:0080923437") "Sympathetic neurons are part of the sympathetic nervous system and are primarily adrenergic producing the neurotransmitter noradrenalin along with other neuropeptides.") @@ -40430,56 +19433,11 @@ AnnotationAssertion( "sympathetic neuron") SubClassOf( ) -# Class: (colon epithelial cell) - -AnnotationAssertion(Annotation( "GOC:NV") "Epithelial cell that is part of the colon epithelium.") -AnnotationAssertion( "colonic epithelial cell") -AnnotationAssertion(rdfs:label "colon epithelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (spiral ganglion neuron) - -AnnotationAssertion(Annotation( "GOC:NV") "Neuron found in the spiral ganglion.") -AnnotationAssertion(rdfs:label "spiral ganglion neuron") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - # Class: (precursor cell) AnnotationAssertion(Annotation( "GOC:dos") "A cell that, by division or terminal differentiation, can give rise to other cell types.") AnnotationAssertion(rdfs:comment "Work is needed on GO 'cell differentiation' before it is clear whether the equivalent class definition 'native cell' that capable_of some 'cell differentiation' works. Also, may want to consider merging this with non-terminally differentiated cell.") AnnotationAssertion(rdfs:label "precursor cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (astrocyte of the forebrain) - -AnnotationAssertion( "An astrocyte of the forebrain.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "forebrain astrocyte") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "astrocyte of the forebrain") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (neuron of the forebrain) - -AnnotationAssertion( "A CNS neuron of the forebrain.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "forebrain neuron") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "neuron of the forebrain") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (forebrain radial glial cell) - -AnnotationAssertion(rdfs:label "forebrain radial glial cell"@en) -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) # Class: (pulmonary ionocyte) @@ -40491,84 +19449,6 @@ AnnotationAssertion(rdfs:label "pulm SubClassOf( ) SubClassOf( ) -# Class: (prostate neuroendocrine cell) - -AnnotationAssertion(Annotation( "PMID:33842835") Annotation( "http://orcid.org/0000-0001-7772-9578") "A neuroendocrine cell that is part of the prostate epithelium.") -AnnotationAssertion( ) -AnnotationAssertion( "neuroendocrine cell of prostate epithelium") -AnnotationAssertion( "neuroendocrine cell of the prostate") -AnnotationAssertion(rdfs:label "prostate neuroendocrine cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (epithelial cell of prostatic urethra) - -AnnotationAssertion(Annotation( "PMID:30566875") "An epithelial cell that is part of the prostatic urethra.") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "epithelial cell of prostatic urethra") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (neutrophillic cytoplasm) - -AnnotationAssertion(Annotation( "GOC:add") "Cytoplasm that exhibits a characteristic staining and color, pale-pink, with Wright-Giemsa stain.") -AnnotationAssertion( ) -AnnotationAssertion( "2010-05-25T01:36:34Z") -AnnotationAssertion(rdfs:label "neutrophillic cytoplasm") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (acidophilic cytoplasm) - -AnnotationAssertion(Annotation( "GOC:add") "Cytoplasm that exhibits a characteristic staining and color, red or pink, with Eosin stain.") -AnnotationAssertion( ) -AnnotationAssertion( "2009-12-22T04:23:25Z") -AnnotationAssertion( "eosinophilic") -AnnotationAssertion(rdfs:label "acidophilic cytoplasm") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (basophilic cytoplasm) - -AnnotationAssertion(Annotation( "GOC:tfm") "Cytoplasm that exhibits molecular interaction for basic dyes under specific pH conditions.") -AnnotationAssertion( ) -AnnotationAssertion( "2009-12-22T04:24:54Z") -AnnotationAssertion(rdfs:label "basophilic cytoplasm") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (polychromatophilic cytoplasm) - -AnnotationAssertion(Annotation( "GOC:tfm") "Cytoplasm that exhibits affinity for both basic and acid stains under specific pH conditions.") -AnnotationAssertion( ) -AnnotationAssertion( "2009-12-28T04:25:23Z") -AnnotationAssertion(rdfs:label "polychromatophilic cytoplasm") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (increased nucleus size) - -AnnotationAssertion(Annotation( "GOC:tfm") "A nucleus size quality which is relatively high compared to the amount of cytoplasm present in the same cell.") -AnnotationAssertion( ) -AnnotationAssertion( "2009-12-23T10:53:24Z") -AnnotationAssertion(rdfs:label "increased nucleus size") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (cartwheel heterochromatin) - -AnnotationAssertion(Annotation( "GOC:tfm") "Heterochromatin that is arranged in a carthwheel pattern.") -AnnotationAssertion( ) -AnnotationAssertion( "2009-12-28T04:28:35Z") -AnnotationAssertion(rdfs:label "cartwheel heterochromatin") -SubClassOf( ) - -# Class: (tracheobronchial serous cell) - -AnnotationAssertion( "Any serous secreting cell that is part of the tracheobronchial epithelium.") -AnnotationAssertion( ) -AnnotationAssertion( "2020-05-07T16:03:27Z"^^xsd:dateTime) -AnnotationAssertion( "serous cell of tracheobronchial tree") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "tracheobronchial serous cell"@en) -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - # Class: (tracheobronchial chondrocyte) AnnotationAssertion( "Any chondrocyte that is part of the tracheobronchial tree.") @@ -40579,39 +19459,6 @@ AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "tracheobronchial chondrocyte"@en) -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (tracheobronchial goblet cell) - -AnnotationAssertion( "Any goblet cell that is part of the tracheobronchial epithelium.") -AnnotationAssertion( ) -AnnotationAssertion( "2020-05-07T18:14:52Z"^^xsd:dateTime) -AnnotationAssertion( "goblet cell of tracheobronchial tree") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "tracheobronchial goblet cell"@en) -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (lymphatic vessel smooth muscle cell) - -AnnotationAssertion(Annotation( "PMID:15109561") "A smooth muscle cell that is part of any lymphatic vessel.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "2020-07-21T12:29:51Z"^^xsd:dateTime) -AnnotationAssertion( "smooth muscle cell of lymphatic vessel") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "lymphatic vessel smooth muscle cell"@en) -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (blood vessel smooth muscle cell) - -AnnotationAssertion(Annotation( "PMID:9108778") "A smooth muscle cell that is part of any blood vessel.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "2020-07-21T12:42:48Z"^^xsd:dateTime) -AnnotationAssertion( "smooth muscle cell of blood vessel") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "blood vessel smooth muscle cell"@en) -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (tracheobronchial smooth muscle cell) @@ -40622,151 +19469,12 @@ AnnotationAssertion( "smooth muscle cell of tracheobronchial tree") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "tracheobronchial smooth muscle cell"@en) -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (extrahepatic cholangiocyte) - -AnnotationAssertion(Annotation( "PMID:23720296") "An epithelial cell of the extrahepatic bile ducts, including the left and right hepatic duct, common hepatic duct, and common bile duct. They are columnar in shape, and have a large nuclear-to-cytoplasmic ratio relative to small/intrahepatic cholangiocytes.") -AnnotationAssertion( ) -AnnotationAssertion( "2020-09-03T12:24:24Z"^^xsd:dateTime) -AnnotationAssertion(Annotation( "PMID:23720296") "large bile duct cholangiocyte") -AnnotationAssertion(rdfs:label "extrahepatic cholangiocyte"@en) -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (endothelial cell of periportal hepatic sinusoid) - -AnnotationAssertion(Annotation( "PMID:27423426") "An endothelial cell found in the periportal region hepatic sinusoid, near the portal triad. The fenestrae of these cells are larger but fewer in number compared with those of endothelial cells near the centrilobular region of the hepatic sinusoid.") -AnnotationAssertion( ) -AnnotationAssertion( "2020-09-09T13:56:47Z"^^xsd:dateTime) -AnnotationAssertion( "EFO:0010705") -AnnotationAssertion(Annotation( "PMID:28287163") "periportal LSEC") -AnnotationAssertion(Annotation( "PMID:30348985") "periportal hepatic sinusoidal endothelial cell") -AnnotationAssertion(rdfs:label "endothelial cell of periportal hepatic sinusoid"@en) -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (endothelial cell of pericentral hepatic sinusoid) - -AnnotationAssertion(Annotation( "PMID:27423426") "An endothelial cell found in the centrilobular region hepatic sinusoid, near the central vein. The fenestrae of these cells are smaller but more numerous compared with those of endothelial cells near the periportal region of the hepatic sinusoid.") -AnnotationAssertion( ) -AnnotationAssertion( "2020-09-10T12:38:29Z"^^xsd:dateTime) -AnnotationAssertion( "EFO:0010706") -AnnotationAssertion(Annotation( "PMID:30348985") "central venous hepatic sinusoidal endothelial cell") -AnnotationAssertion(Annotation( "PMID:28287163") "pericentral LSEC") -AnnotationAssertion(rdfs:label "endothelial cell of pericentral hepatic sinusoid"@en) -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (periportal region hepatocyte) - -AnnotationAssertion(Annotation( "PMID:29763190") "Any hepatocyte that is part of the liver lobule periportal region. These cells are primarily involved in oxidative energy metabolism.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "2020-10-12T10:29:31Z"^^xsd:dateTime) -AnnotationAssertion(Annotation( "PMID:29763190") "periportal hepatocyte") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "periportal region hepatocyte"@en) -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (midzonal region hepatocyte) - -AnnotationAssertion(Annotation( "PMID:29763190") "Any hepatocyte that is part of the liver lobule midzonal region. These cells have mixed functionality in comparison with those in the other two regions of the liver lobule.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "2020-10-12T10:57:40Z"^^xsd:dateTime) -AnnotationAssertion(Annotation( "PMID:29763190") "midzonal hepatocyte") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "midzonal region hepatocyte"@en) -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (centrilobular region hepatocyte) - -AnnotationAssertion(Annotation( "PMID:29763190") "Any hepatocyte that is part of the liver lobule centrilobular region. These cells are the primary location for the biotransformation of drugs.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "2020-10-12T11:03:51Z"^^xsd:dateTime) -AnnotationAssertion(Annotation( "PMID:29763190") "centrilobular hepatocyte") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "centrilobular region hepatocyte"@en) -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (intestine goblet cell) - -AnnotationAssertion(Annotation( "PMID:1996606") Annotation( "PMID:24942678") "Goblet cells reside throughout the length of the small and large intestine and are responsible for the production and maintenance of the protective mucus blanket by synthesizing and secreting high-molecular-weight glycoproteins known as mucins. Human intestinal goblet cells secrete the MUC2 mucin, as well as a number of typical mucus components: CLCA1, FCGBP, AGR2, ZG16, and TFF3.") -AnnotationAssertion( ) -AnnotationAssertion( "2020-10-14T14:59:07Z"^^xsd:dateTime) -AnnotationAssertion(Annotation( "PMID:1996606") "intestinal goblet cell") -AnnotationAssertion(rdfs:label "intestine goblet cell"@en) -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (intestinal tuft cell) - -AnnotationAssertion(Annotation( "PMID:22527717") "Any brush cell that is part of the intestinal epithelium.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "2020-10-15T12:47:46Z"^^xsd:dateTime) -AnnotationAssertion(Annotation( "PMID:22527717") "intestinal brush cell") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "intestinal tuft cell"@en) -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (retrotrapezoid nucleus neuron) - -AnnotationAssertion(rdfs:label "retrotrapezoid nucleus neuron") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (mesonephric nephron tubule epithelial cell) - -AnnotationAssertion(rdfs:label "mesonephric nephron tubule epithelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (forebrain neuroblast) - -AnnotationAssertion(rdfs:label "forebrain neuroblast") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (lateral line nerve glial cell) - -AnnotationAssertion(rdfs:label "lateral line nerve glial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (spinal cord radial glial cell) - -AnnotationAssertion(rdfs:label "spinal cord radial glial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (pronephric nephron tubule epithelial cell) - -AnnotationAssertion(rdfs:label "pronephric nephron tubule epithelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (metanephric nephron tubule epithelial cell) - -AnnotationAssertion(rdfs:label "metanephric nephron tubule epithelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (lung goblet cell) AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "lung goblet cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cardiac valve cell) - -AnnotationAssertion(Annotation( "PMID:25311230") "A cell that is part of a cardiac valve.") -AnnotationAssertion(Annotation( "PMID:30796046") "heart valve cell") -AnnotationAssertion(rdfs:label "cardiac valve cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (growth plate cartilage chondrocyte) - -AnnotationAssertion(rdfs:label "growth plate cartilage chondrocyte") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (stomach neuroendocrine cell) - -AnnotationAssertion(rdfs:label "stomach neuroendocrine cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (lung neuroendocrine cell) @@ -40776,193 +19484,29 @@ AnnotationAssertion(Annotation( "PMID:33355253") Annotation( ) "PNEC") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "lung neuroendocrine cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (posterior lateral line nerve glial cell) - -AnnotationAssertion(rdfs:label "posterior lateral line nerve glial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (anterior lateral line nerve glial cell) - -AnnotationAssertion(rdfs:label "anterior lateral line nerve glial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (posterior lateral line ganglion neuron) - -AnnotationAssertion(rdfs:label "posterior lateral line ganglion neuron") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (lung ciliated cell) AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "lung ciliated cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) SubClassOf( ) -# Class: (lung secretory cell) - -AnnotationAssertion(rdfs:label "lung secretory cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - # Class: (trophectodermal cell) AnnotationAssertion( "trophectoderm cell") AnnotationAssertion(rdfs:label "trophectodermal cell") SubClassOf( ) -# Class: (smooth muscle cell of small intestine) - -AnnotationAssertion(Annotation( "GOC:tfm") "A smooth muscle cell that is part of the small intestine.") -AnnotationAssertion( "FMA:15050") -AnnotationAssertion(Annotation( "FMA:15050") "non-striated muscle fiber of small intestine") -AnnotationAssertion(rdfs:label "smooth muscle cell of small intestine") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (smooth muscle fiber of duodenum) - -AnnotationAssertion(Annotation( "GOC:tfm") "A smooth muscle cell that is part of the duodenum.") -AnnotationAssertion( "FMA:15058") -AnnotationAssertion(Annotation( "FMA:15058") "non-striated muscle fiber of duodenum") -AnnotationAssertion(rdfs:label "smooth muscle fiber of duodenum") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (smooth muscle fiber of jejunum) - -AnnotationAssertion(Annotation( "GOC:tfm") "A smooth muscle cell that is part of the jejunum.") -AnnotationAssertion( "FMA:15062") -AnnotationAssertion(Annotation( "FMA:15062") "non-striated muscle fiber of jejunum") -AnnotationAssertion(rdfs:label "smooth muscle fiber of jejunum") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (smooth muscle fiber of ileum) - -AnnotationAssertion(Annotation( "GOC:tfm") "A smooth muscle cell that is part of the ileum.") -AnnotationAssertion( "FMA:15066") -AnnotationAssertion(Annotation( "FMA:15066") "non-striated muscle fiber of ileum") -AnnotationAssertion(rdfs:label "smooth muscle fiber of ileum") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (smooth muscle cell of large intestine) - -AnnotationAssertion(Annotation( "GOC:tfm") "A smooth muscle cell that is part of the large intestine.") -AnnotationAssertion( ) -AnnotationAssertion( "FMA:15653") -AnnotationAssertion(Annotation( "FMA:15653") "non-striated muscle fiber of large intestine") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "smooth muscle cell of large intestine") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (smooth muscle cell of colon) - -AnnotationAssertion(Annotation( "GOC:tfm") "A smooth muscle cell that is part of the colon.") -AnnotationAssertion( "FMA:15663") -AnnotationAssertion(Annotation( "FMA:15663") "non-striated muscle fiber of colon") -AnnotationAssertion(rdfs:label "smooth muscle cell of colon") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (smooth muscle cell of cecum) - -AnnotationAssertion(Annotation( "GOC:tfm") "A smooth muscle cell that is part of the cecum.") -AnnotationAssertion( "FMA:15681") -AnnotationAssertion(Annotation( "FMA:15681") "non-striated muscle fiber of cecum") -AnnotationAssertion( "smooth muscle fiber of cecum") -AnnotationAssertion(rdfs:label "smooth muscle cell of cecum") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (smooth muscle fiber of ascending colon) - -AnnotationAssertion(Annotation( "GOC:tfm") "A smooth muscle cell that is part of the ascending colon.") -AnnotationAssertion( "FMA:17518") -AnnotationAssertion(Annotation( "FMA:17518") "non-striated muscle fiber of ascending colon") -AnnotationAssertion(rdfs:label "smooth muscle fiber of ascending colon") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (smooth muscle fiber of transverse colon) - -AnnotationAssertion(Annotation( "GOC:tfm") "A smooth muscle cell that is part of the transverse colon.") -AnnotationAssertion( "FMA:17519") -AnnotationAssertion(Annotation( "FMA:17519") "non-striated muscle fiber of transverse colon") -AnnotationAssertion(rdfs:label "smooth muscle fiber of transverse colon") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (smooth muscle fiber of descending colon) - -AnnotationAssertion(Annotation( "GOC:tfm") "A smooth muscle cell that is part of the descending colon.") -AnnotationAssertion( "FMA:17520") -AnnotationAssertion(Annotation( "FMA:17520") "non-striated muscle fiber of descending colon") -AnnotationAssertion(rdfs:label "smooth muscle fiber of descending colon") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (smooth muscle cell of sigmoid colon) - -AnnotationAssertion(Annotation( "GOC:tfm") "A smooth muscle cell that is part of the sigmoid colon.") -AnnotationAssertion( "FMA:17521") -AnnotationAssertion(Annotation( "FMA:17521") "non-striated muscle fiber of sigmoid colon") -AnnotationAssertion(rdfs:label "smooth muscle cell of sigmoid colon") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (smooth muscle cell of rectum) - -AnnotationAssertion(Annotation( "GOC:tfm") "A smooth muscle cell that is part of the rectum.") -AnnotationAssertion( "FMA:17522") -AnnotationAssertion(Annotation( "FMA:17522") "non-striated muscle fiber of rectum") -AnnotationAssertion( "smooth muscle fiber of rectum") -AnnotationAssertion(rdfs:label "smooth muscle cell of rectum") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (epithelial cell of urethra) - -AnnotationAssertion(Annotation( "GOC:tfm") "An epithelial cell that is part of the urethra.") -AnnotationAssertion( "FMA:256165") -AnnotationAssertion(rdfs:label "epithelial cell of urethra") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) - -# Class: (mesothelial cell of dura mater) - -AnnotationAssertion(Annotation( "GOC:tfm") "A mesothelial cell that is part of the dura mater.") -AnnotationAssertion( "FMA:256516") -AnnotationAssertion(Annotation( "FMA:256516") "squamous mesothelial cell of dura mater") -AnnotationAssertion(rdfs:label "mesothelial cell of dura mater") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) - -# Class: (fibroblast of papillary layer of dermis) - -AnnotationAssertion(Annotation( "GOC:tfm") "A fibroblast that is part of the papillary layer of dermis.") -AnnotationAssertion( "FMA:261277") -AnnotationAssertion(rdfs:label "fibroblast of papillary layer of dermis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - # Class: (fibroblast of areolar connective tissue) AnnotationAssertion(Annotation( "GOC:tfm") "A fibroblast that is part of the areolar connective tissue.") AnnotationAssertion( "FMA:261279") AnnotationAssertion(rdfs:label "fibroblast of areolar connective tissue") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) SubClassOf( ObjectSomeValuesFrom( )) @@ -40971,28 +19515,8 @@ SubClassOf( ObjectSomeValuesFrom( "GOC:tfm") "A fibroblast that is part of the tunica adventitia of artery.") AnnotationAssertion( "FMA:261285") AnnotationAssertion(rdfs:label "fibroblast of tunica adventitia of artery") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) -# Class: (fibroblast of dense regular elastic tissue) - -AnnotationAssertion(Annotation( "GOC:tfm") "A fibroblast that is part of the dense regular elastic tissue.") -AnnotationAssertion( "FMA:261287") -AnnotationAssertion(rdfs:label "fibroblast of dense regular elastic tissue") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (fibrocyte of adventitia of ureter) - -AnnotationAssertion(Annotation( "GOC:tfm") "A fibrocyte that is part of the adventitia of ureter.") -AnnotationAssertion( ) -AnnotationAssertion( "FMA:261289") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "fibrocyte of adventitia of ureter") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - # Class: (epicardial adipocyte) AnnotationAssertion(Annotation( "GOC:tfm") "A fat cell that is part of the epicardial fat.") @@ -41005,256 +19529,11 @@ AnnotationAssertion(rdfs:label "epic SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (adipocyte of epicardial fat of right ventricle) - -AnnotationAssertion(Annotation( "GOC:tfm") "A fat cell that is part of the epicardial fat of right ventricle.") -AnnotationAssertion( "FMA:261297") -AnnotationAssertion(Annotation( "FMA:261297") "epicardial adipocyte of right ventricle") -AnnotationAssertion(Annotation( "FMA:261297") "epicardial fat cell of right ventricle") -AnnotationAssertion(rdfs:label "adipocyte of epicardial fat of right ventricle") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (adipocyte of epicardial fat of left ventricle) - -AnnotationAssertion(Annotation( "GOC:tfm") "A fat cell that is part of the epicardial fat of left ventricle.") -AnnotationAssertion( "FMA:261300") -AnnotationAssertion(Annotation( "FMA:261300") "epicardial adipocyte of left ventricle") -AnnotationAssertion(Annotation( "FMA:261300") "epicardial fat cell of left ventricle") -AnnotationAssertion(rdfs:label "adipocyte of epicardial fat of left ventricle") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (bronchial goblet cell) - -AnnotationAssertion(Annotation( "GOC:tfm") "A goblet cell that is part of the epithelium of bronchus.") -AnnotationAssertion( "FMA:263032") -AnnotationAssertion(Annotation( "FMA:263032") "goblet cell of epithelium of bronchus") -AnnotationAssertion(rdfs:label "bronchial goblet cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (gastric goblet cell) - -AnnotationAssertion(Annotation( "GOC:tfm") "A goblet cell that is part of the epithelium of stomach.") -AnnotationAssertion( "FMA:263035") -AnnotationAssertion(Annotation( "FMA:263035") "goblet cell of epithelium of stomach") -AnnotationAssertion(rdfs:label "gastric goblet cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (gastric cardiac gland goblet cell) - -AnnotationAssertion(Annotation( "GOC:tfm") "A goblet cell that is part of the epithelium of gastric cardiac gland.") -AnnotationAssertion( "FMA:263038") -AnnotationAssertion( "goblet cell of epithelium of gastric cardiac gland") -AnnotationAssertion(rdfs:label "gastric cardiac gland goblet cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( )))) - -# Class: (principal gastric gland goblet cell) - -AnnotationAssertion(Annotation( "GOC:tfm") "A goblet cell that is part of the epithelium of principal gastric gland.") -AnnotationAssertion( "FMA:263040") -AnnotationAssertion( "goblet cell of epithelium of principal gastric gland") -AnnotationAssertion(rdfs:label "principal gastric gland goblet cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (intestinal villus goblet cell) - -AnnotationAssertion(Annotation( "GOC:tfm") "A goblet cell that is part of the epithelium of intestinal villus.") -AnnotationAssertion( "FMA:263046") -AnnotationAssertion( "goblet cell of epithelium of intestinal villus") -AnnotationAssertion(rdfs:label "intestinal villus goblet cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (large intestine goblet cell) - -AnnotationAssertion(Annotation( "GOC:tfm") "A goblet cell that is part of the epithelium of large intestine.") -AnnotationAssertion( "FMA:263054") -AnnotationAssertion( "goblet cell of epithelium of large intestine") -AnnotationAssertion(rdfs:label "large intestine goblet cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (large intestine crypt goblet cell) - -AnnotationAssertion(Annotation( "GOC:tfm") "A goblet cell that is part of the epithelium of crypt of Lieberkuhn of large intestine.") -AnnotationAssertion( ) -AnnotationAssertion( "FMA:263056") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "large intestine crypt goblet cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))))) -SubClassOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( )))))) - -# Class: (pancreatic goblet cell) - -AnnotationAssertion(Annotation( "GOC:tfm") "A goblet cell that is part of the epithelium of pancreatic duct.") -AnnotationAssertion( ) -AnnotationAssertion( "FMA:263058") -AnnotationAssertion(Annotation( "FMA:263058") "goblet cell of epithelium of pancreatic duct") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "pancreatic goblet cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (pyloric gastric gland goblet cell) - -AnnotationAssertion(Annotation( "GOC:tfm") "A goblet cell that is part of the epithelium of pyloric gland.") -AnnotationAssertion( "FMA:263061") -AnnotationAssertion( "goblet cell of epithelium of pyloric gland") -AnnotationAssertion(rdfs:label "pyloric gastric gland goblet cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( )))) - -# Class: (duodenal goblet cell) - -AnnotationAssertion(Annotation( "GOC:tfm") "A goblet cell that is part of the epithelium proper of duodenum.") -AnnotationAssertion( ) -AnnotationAssertion( "FMA:263063") -AnnotationAssertion( "goblet cell of epithelium proper of duodenum") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "duodenal goblet cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (jejunal goblet cell) - -AnnotationAssertion(Annotation( "GOC:tfm") "A goblet cell that is part of the epithelium proper of jejunum.") -AnnotationAssertion( ) -AnnotationAssertion( "FMA:263065") -AnnotationAssertion( "goblet cell of epithelium proper of jejunum") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "jejunal goblet cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( )))) - -# Class: (ileal goblet cell) - -AnnotationAssertion(Annotation( "GOC:tfm") "A goblet cell that is part of the epithelium proper of ileum.") -AnnotationAssertion( "FMA:263067") -AnnotationAssertion( "goblet cell of epithelium proper of ileum") -AnnotationAssertion(rdfs:label "ileal goblet cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( )))) - -# Class: (appendix goblet cell) - -AnnotationAssertion(Annotation( "GOC:tfm") "A goblet cell that is part of the epithelium proper of appendix.") -AnnotationAssertion( "FMA:263069") -AnnotationAssertion( "goblet cell of epithelium proper of appendix") -AnnotationAssertion(rdfs:label "appendix goblet cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( )))) - -# Class: (tracheal goblet cell) - -AnnotationAssertion(Annotation( "GOC:tfm") "A goblet cell that is part of the epithelium of trachea.") -AnnotationAssertion( ) -AnnotationAssertion( "FMA:263075") -AnnotationAssertion(Annotation( "FMA:263075") "goblet cell of epithelium of trachea") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "tracheal goblet cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (serous cell of epithelium of trachea) - -AnnotationAssertion(Annotation( "GOC:tfm") "A serous secreting cell that is part of the epithelium of trachea.") -AnnotationAssertion( ) -AnnotationAssertion( "FMA:263078") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "serous cell of epithelium of trachea") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) - -# Class: (serous cell of epithelium of bronchus) - -AnnotationAssertion(Annotation( "GOC:tfm") "A serous secreting cell that is part of the epithelium of bronchus.") -AnnotationAssertion( ) -AnnotationAssertion( "FMA:263080") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "serous cell of epithelium of bronchus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (serous cell of epithelium of terminal bronchiole) - -AnnotationAssertion(Annotation( "GOC:tfm") "A serous secreting cell that is part of the epithelium of terminal bronchiole.") -AnnotationAssertion( "FMA:263082") -AnnotationAssertion(rdfs:label "serous cell of epithelium of terminal bronchiole") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (serous cell of epithelium of lobular bronchiole) - -AnnotationAssertion(Annotation( "GOC:tfm") "A serous secreting cell that is part of the epithelium of bronchiole.") -AnnotationAssertion( "FMA:263084") -AnnotationAssertion(rdfs:label "serous cell of epithelium of lobular bronchiole") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (transitional myocyte of interatrial septum) - -AnnotationAssertion(Annotation( "GOC:tfm") "A transitional myocyte that is part of the interatrial septum.") -AnnotationAssertion( "FMA:263152") -AnnotationAssertion(rdfs:label "transitional myocyte of interatrial septum") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (transitional myocyte of interventricular septum) - -AnnotationAssertion(Annotation( "GOC:tfm") "A transitional myocyte that is part of the interventricular septum.") -AnnotationAssertion( "FMA:263154") -AnnotationAssertion(rdfs:label "transitional myocyte of interventricular septum") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (transitional myocyte of left branch of atrioventricular bundle) - -AnnotationAssertion(Annotation( "GOC:tfm") "A transitional myocyte that is part of the left branch of atrioventricular bundle.") -AnnotationAssertion( "FMA:263170") -AnnotationAssertion(rdfs:label "transitional myocyte of left branch of atrioventricular bundle") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (transitional myocyte of right branch of atrioventricular bundle) - -AnnotationAssertion(Annotation( "GOC:tfm") "A transitional myocyte that is part of the right branch of atrioventricular bundle.") -AnnotationAssertion( "FMA:263172") -AnnotationAssertion(rdfs:label "transitional myocyte of right branch of atrioventricular bundle") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (Purkinje myocyte of interventricular septum) - -AnnotationAssertion(Annotation( "GOC:tfm") "A Purkinje myocyte that is part of the interventricular septum.") -AnnotationAssertion( "FMA:263182") -AnnotationAssertion(rdfs:label "Purkinje myocyte of interventricular septum") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (type 1 vestibular sensory cell of stato-acoustic epithelium) - -AnnotationAssertion(Annotation( "GOC:tfm") "A type I vestibular sensory cell that is part of the stato-acoustic epithelium.") -AnnotationAssertion( "FMA:263186") -AnnotationAssertion(rdfs:label "type 1 vestibular sensory cell of stato-acoustic epithelium") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (type 1 vestibular sensory cell of epithelium of macula of utricle of membranous labyrinth) AnnotationAssertion(Annotation( "GOC:tfm") "A type I vestibular sensory cell that is part of the epithelium of macula of utricle of membranous labyrinth.") AnnotationAssertion( "FMA:263188") AnnotationAssertion(rdfs:label "type 1 vestibular sensory cell of epithelium of macula of utricle of membranous labyrinth") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ObjectSomeValuesFrom( )) # Class: (type 1 vestibular sensory cell of epithelium of macula of saccule of membranous labyrinth) @@ -41262,29 +19541,13 @@ SubClassOf( ObjectSomeValuesFrom( "GOC:tfm") "A type I vestibular sensory cell that is part of the epithelium of macula of saccule of membranous labyrinth.") AnnotationAssertion( "FMA:263190") AnnotationAssertion(rdfs:label "type 1 vestibular sensory cell of epithelium of macula of saccule of membranous labyrinth") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (type 1 vestibular sensory cell of epithelium of crista of ampulla of semicircular duct of membranous labyrinth) - -AnnotationAssertion(Annotation( "GOC:tfm") "A type I vestibular sensory cell that is part of the epithelium of crista of ampulla of semicircular duct of membranous labyrinth.") -AnnotationAssertion( "FMA:263192") -AnnotationAssertion(rdfs:label "type 1 vestibular sensory cell of epithelium of crista of ampulla of semicircular duct of membranous labyrinth") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (type 2 vestibular sensory cell of stato-acoustic epithelium) - -AnnotationAssertion(Annotation( "GOC:tfm") "A type II vestibular sensory cell that is part of the stato-acoustic epithelium.") -AnnotationAssertion( "FMA:263194") -AnnotationAssertion(rdfs:label "type 2 vestibular sensory cell of stato-acoustic epithelium") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (type 2 vestibular sensory cell of epithelium of macula of utricle of membranous labyrinth) AnnotationAssertion(Annotation( "GOC:tfm") "A type II vestibular sensory cell that is part of the epithelium of macula of utricle of membranous labyrinth.") AnnotationAssertion( "FMA:263196") AnnotationAssertion(rdfs:label "type 2 vestibular sensory cell of epithelium of macula of utricle of membranous labyrinth") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ObjectSomeValuesFrom( )) # Class: (type 2 vestibular sensory cell of epithelium of macula of saccule of membranous labyrinth) @@ -41292,72 +19555,18 @@ SubClassOf( ObjectSomeValuesFrom( "GOC:tfm") "A type II vestibular sensory cell that is part of the epithelium of macula of saccule of membranous labyrinth.") AnnotationAssertion( "FMA:263198") AnnotationAssertion(rdfs:label "type 2 vestibular sensory cell of epithelium of macula of saccule of membranous labyrinth") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (type 2 vestibular sensory cell of epithelium of crista of ampulla of semicircular duct of membranous labyrinth) - -AnnotationAssertion(Annotation( "GOC:tfm") "A type II vestibular sensory cell that is part of the epithelium of crista of ampulla of semicircular duct of membranous labyrinth.") -AnnotationAssertion( "FMA:263200") -AnnotationAssertion(rdfs:label "type 2 vestibular sensory cell of epithelium of crista of ampulla of semicircular duct of membranous labyrinth") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (melanocyte of eyelid) - -AnnotationAssertion(Annotation( "GOC:tfm") "A melanocyte that is part of the eyelid.") -AnnotationAssertion( "FMA:59175") -AnnotationAssertion(Annotation( "FMA:59175") "eyelid melanocyte") -AnnotationAssertion(Annotation( "FMA:59175") "sebaceous gland of wolff") -AnnotationAssertion(rdfs:label "melanocyte of eyelid") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) - -# Class: (endothelial cell of venous sinus of red pulp of spleen) - -AnnotationAssertion(Annotation( "GOC:tfm") "An endothelial cell that is part of the venous sinus of red pulp of spleen.") -AnnotationAssertion( "FMA:62817") -AnnotationAssertion(rdfs:comment "todo - add logical definition to UBERON:0009967") -AnnotationAssertion(rdfs:label "endothelial cell of venous sinus of red pulp of spleen") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (endothelial cell of hepatic sinusoid) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:3926620") "An endothelial cell that is part of the hepatic sinusoid. These cells possess flattened areas containing perforations about 0.1 micrometers in diameter, known as fenestrae. The fenestrae are arranged in groups known as sieve plates.") -AnnotationAssertion( ) -AnnotationAssertion( "BTO:000125") -AnnotationAssertion( "FMA:62911") -AnnotationAssertion(Annotation( "PMID:30348985") "LSEC") -AnnotationAssertion(Annotation( "FMA:62911") "endotheliocyte of hepatic sinusoid") -AnnotationAssertion(Annotation( "PMID:30348985") "liver sinusoidal endothelial cell") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "endothelial cell of hepatic sinusoid") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (epithelial cell of appendix) - -AnnotationAssertion(Annotation( "GOC:tfm") "An epithelial cell that is part of the appendix.") -AnnotationAssertion( "FMA:63602") -AnnotationAssertion(Annotation( "FMA:63602") "columnar epitheliocyte of appendix") -AnnotationAssertion(Annotation( "FMA:63602") "epithelial cell of vermiform appendix") -AnnotationAssertion(rdfs:label "epithelial cell of appendix") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) - # Class: (myocyte of sinoatrial node) AnnotationAssertion(Annotation( "FMA:67102") Annotation( "GOC:tfm") "A muscle cell that is part of the sinoatrial node.") AnnotationAssertion( "FMA:67102") AnnotationAssertion(Annotation( "FMA:67102") "SA nodal myocyte") AnnotationAssertion(Annotation( "GOC:pr") "SA node cardiac muscle cell") -AnnotationAssertion(Annotation( "FMA:67102") "myocyte of sinoatrial node") AnnotationAssertion(Annotation( "GOC:pr") "sinoatrial node cell") AnnotationAssertion( "sinoatrial node myocyte") AnnotationAssertion(Annotation( "FMA:67102") "sinuatrial node myocyte") AnnotationAssertion(rdfs:label "myocyte of sinoatrial node") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) # Class: (myocyte of atrioventricular node) @@ -41370,113 +19579,14 @@ AnnotationAssertion(Annotation( "GOC:pr") "atrioventricular node cell") AnnotationAssertion(Annotation( "FMA:67106") "atrioventricular node myocyte") AnnotationAssertion(rdfs:label "myocyte of atrioventricular node") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (endothelial cell of Peyer's patch) - -AnnotationAssertion(Annotation( "GOC:tfm") "An endothelial cell that is part of the small intestine Peyer's patch.") -AnnotationAssertion( "FMA:67757") -AnnotationAssertion(rdfs:label "endothelial cell of Peyer's patch") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (endothelial cell of arteriole) - -AnnotationAssertion(Annotation( "GOC:tfm") "An endothelial cell that is part of the arteriole.") -AnnotationAssertion( ) -AnnotationAssertion( "FMA:67760") -AnnotationAssertion( "KUPO:0001097") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "endothelial cell of arteriole") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (endothelial cell of artery) - -AnnotationAssertion(Annotation( "GOC:tfm") "A blood vessel endothelial cell that is part of an arterial endothelium.") -AnnotationAssertion( ) -AnnotationAssertion( "BTO:0004758") -AnnotationAssertion( "FMA:67761") -AnnotationAssertion( "KUPO:0001095") -AnnotationAssertion( "arterial endothelial cell") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "endothelial cell of artery") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (endothelial cell of venule) - -AnnotationAssertion(Annotation( "GOC:tfm") "An endothelial cell that is part of the venule.") -AnnotationAssertion( ) -AnnotationAssertion( "FMA:67762") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "endothelial cell of venule") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (epithelial cell of gallbladder) - -AnnotationAssertion(Annotation( "GOC:tfm") "An epithelial cell that is part of the gallbladder.") -AnnotationAssertion( "FMA:67780") -AnnotationAssertion(rdfs:label "epithelial cell of gallbladder") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) - -# Class: (myoepithelial cell of sweat gland) - -AnnotationAssertion(Annotation( "GOC:tfm") "A myoepithelial cell that is part of the sweat gland.") -AnnotationAssertion( ) -AnnotationAssertion( "FMA:67801") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "myoepithelial cell of sweat gland") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (myoepithelial cell of lactiferous alveolus) - -AnnotationAssertion(Annotation( "GOC:tfm") "A myoepithelial cell that is part of the mammary gland alveolus.") -AnnotationAssertion( "FMA:67802") -AnnotationAssertion(Annotation( "FMA:67802") "basal cell of alveolus of lactiferous gland") -AnnotationAssertion(Annotation( "FMA:67802") "myoepithelial cell of mammary alveolus") -AnnotationAssertion(rdfs:label "myoepithelial cell of lactiferous alveolus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (myoepithelial cell of lactiferous duct) - -AnnotationAssertion(Annotation( "GOC:tfm") "A myoepithelial cell that is part of the lactiferous duct.") -AnnotationAssertion( "FMA:67803") -AnnotationAssertion(rdfs:label "myoepithelial cell of lactiferous duct") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (chromaffin cell of paraaortic body) - -AnnotationAssertion(Annotation( "GOC:tfm") "A chromaffin cell that is part of the paraaortic body.") -AnnotationAssertion( "FMA:69328") -AnnotationAssertion(Annotation( "FMA:69328") "chromaffin cell of para-aortic body") -AnnotationAssertion(rdfs:label "chromaffin cell of paraaortic body") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (chromaffin cell of paraganglion) - -AnnotationAssertion(Annotation( "GOC:tfm") "A chromaffin cell that is part of the paraganglion.") -AnnotationAssertion( "FMA:69335") -AnnotationAssertion(rdfs:label "chromaffin cell of paraganglion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - # Class: (chromaffin cell of adrenal gland) AnnotationAssertion(Annotation( "GOC:tfm") "A chromaffin cell that is part of the adrenal gland.") AnnotationAssertion( "FMA:69794") AnnotationAssertion(Annotation( "GO:0061104") "adrenal chromaffin cell") AnnotationAssertion(rdfs:label "chromaffin cell of adrenal gland") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf(Annotation( "true") ) @@ -41487,309 +19597,8 @@ AnnotationAssertion( "chromaffin cell of adrenal cortex") AnnotationAssertion(rdfs:comment "Not clear this cell type exists. Can't call it a cortical adrenal cell because of different germ layer origin.") AnnotationAssertion(rdfs:label "adrenal cortex chromaffin cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) -# Class: (stem cell of epidermis) - -AnnotationAssertion(Annotation( "GOC:tfm") "A somatic stem cell that is part of the epidermis.") -AnnotationAssertion( "FMA:70541") -AnnotationAssertion(Annotation( "FMA:70541") "epidermal stem cell") -AnnotationAssertion(rdfs:label "stem cell of epidermis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (conjunctival epithelial cell) - -AnnotationAssertion(Annotation( "GOC:tfm") "An epithelial cell that is part of the conjunctiva.") -AnnotationAssertion( "FMA:70552") -AnnotationAssertion(Annotation( "FMA:70552") "epithelial cell of conjunctiva") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "conjunctival epithelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) - -# Class: (epithelial cell of lacrimal canaliculus) - -AnnotationAssertion(Annotation( "GOC:tfm") "An epithelial cell that is part of the lacrimal canaliculus.") -AnnotationAssertion( "FMA:70553") -AnnotationAssertion(rdfs:label "epithelial cell of lacrimal canaliculus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) - -# Class: (epithelial cell of external acoustic meatus) - -AnnotationAssertion(Annotation( "GOC:tfm") "An epithelial cell that is part of the external acoustic meatus.") -AnnotationAssertion( "FMA:70555") -AnnotationAssertion(rdfs:label "epithelial cell of external acoustic meatus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) - -# Class: (epithelial cell of lacrimal duct) - -AnnotationAssertion(Annotation( "GOC:tfm") "An epithelial cell that is part of the lacrimal duct.") -AnnotationAssertion( "FMA:70559") -AnnotationAssertion(rdfs:label "epithelial cell of lacrimal duct") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (epithelial cell of lacrimal sac) - -AnnotationAssertion(Annotation( "GOC:tfm") "An epithelial cell that is part of the lacrimal sac.") -AnnotationAssertion( "FMA:70560") -AnnotationAssertion(rdfs:label "epithelial cell of lacrimal sac") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) - -# Class: (epithelial cell of nasolacrimal duct) - -AnnotationAssertion(Annotation( "GOC:tfm") "An epithelial cell that is part of the nasolacrimal duct.") -AnnotationAssertion( "FMA:70561") -AnnotationAssertion(rdfs:label "epithelial cell of nasolacrimal duct") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (urothelial cell of trigone of urinary bladder) - -AnnotationAssertion(Annotation( "GOC:tfm") "An urothelial cell that is part of the trigone of urinary bladder.") -AnnotationAssertion( "FMA:70598") -AnnotationAssertion(Annotation( "FMA:70598") "epithelial cell of vesical trigone") -AnnotationAssertion(rdfs:label "urothelial cell of trigone of urinary bladder") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))))) - -# Class: (ciliary muscle cell) - -AnnotationAssertion(Annotation( "GOC:tfm") "A smooth muscle cell that is part of the ciliary body.") -AnnotationAssertion( "FMA:70610") -AnnotationAssertion(Annotation( "FMA:70610") "smooth muscle cell of ciliary body") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "ciliary muscle cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (mesothelial cell of anterior chamber of eye) - -AnnotationAssertion(Annotation( "GOC:tfm") "A mesothelial cell that is part of the anterior chamber of eyeball.") -AnnotationAssertion( "FMA:70615") -AnnotationAssertion(rdfs:label "mesothelial cell of anterior chamber of eye") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) - -# Class: (myoepithelial cell of dilator pupillae) - -AnnotationAssertion(Annotation( "GOC:tfm") "A myoepithelial cell that is part of the dilatator pupillae.") -AnnotationAssertion( "FMA:70619") -AnnotationAssertion(rdfs:label "myoepithelial cell of dilator pupillae") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (epithelial cell of stratum germinativum of esophagus) - -AnnotationAssertion(Annotation( "GOC:tfm") "A basal cell that is part of the epithelium of esophagus.") -AnnotationAssertion( "FMA:70731") -AnnotationAssertion(Annotation( "FMA:70731") "basal cell of esophageal epithelium") -AnnotationAssertion(rdfs:label "epithelial cell of stratum germinativum of esophagus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (epithelial cell of sweat gland) - -AnnotationAssertion(Annotation( "GOC:tfm") "An epithelial cell that is part of the sweat gland.") -AnnotationAssertion( "FMA:70952") -AnnotationAssertion(rdfs:label "epithelial cell of sweat gland") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) - -# Class: (epithelial cell of nephron) - -AnnotationAssertion(Annotation( "GOC:tfm") "An epithelial cell that is part of the nephron.") -AnnotationAssertion( "FMA:70965") -AnnotationAssertion(rdfs:label "epithelial cell of nephron") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) - -# Class: (epithelial cell of glomerular capsule) - -AnnotationAssertion(Annotation( "GOC:tfm") "An epithelial cell that is part of the glomerular capsule.") -AnnotationAssertion( "FMA:70966") -AnnotationAssertion( "KUPO:0001034") -AnnotationAssertion( "Bowmans capsule epithelial cell") -AnnotationAssertion(Annotation( "FMA:70966") "epithelial cell of Bowman's capsule") -AnnotationAssertion(rdfs:label "epithelial cell of glomerular capsule") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) -SubClassOf( ) -SubClassOf(Annotation( "true") ) - -# Class: (parietal epithelial cell) - -AnnotationAssertion(Annotation( "GOC:tfm") "An epithelial cell that is part of the glomerular parietal epithelium.") -AnnotationAssertion( ) -AnnotationAssertion( "FMA:70968") -AnnotationAssertion( "KUPO:0001035") -AnnotationAssertion(Annotation( "FMA:70968") "epithelial cell of parietal layer of glomerular capsule") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "parietal epithelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (epithelial cell of intermediate tubule) - -AnnotationAssertion(Annotation( "GOC:tfm") "An epithelial cell that is part of the intermediate tubule.") -AnnotationAssertion( "FMA:70980") -AnnotationAssertion(rdfs:label "epithelial cell of intermediate tubule") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) - -# Class: (kidney collecting duct epithelial cell) - -AnnotationAssertion(Annotation( "GOC:tfm") "An epithelial cell that is part of the collecting duct of renal tubule.") -AnnotationAssertion( ) -AnnotationAssertion( "FMA:70982") -AnnotationAssertion( "KUPO:0001059") -AnnotationAssertion(Annotation( "FMA:70982") "epithelial cell of renal collecting tubule") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "kidney collecting duct epithelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) - -# Class: (mesothelial cell of parietal peritoneum) - -AnnotationAssertion(Annotation( "GOC:tfm") "A mesothelial cell that is part of the parietal peritoneum.") -AnnotationAssertion( "FMA:72142") -AnnotationAssertion(rdfs:label "mesothelial cell of parietal peritoneum") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) - -# Class: (mesothelial cell of visceral peritoneum) - -AnnotationAssertion(Annotation( "GOC:tfm") "A mesothelial cell that is part of the visceral peritoneum.") -AnnotationAssertion( ) -AnnotationAssertion( "FMA:72143") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "mesothelial cell of visceral peritoneum") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) - -# Class: (melanocyte of skin) - -AnnotationAssertion(Annotation( "GOC:tfm") "A melanocyte that is part of the skin of body.") -AnnotationAssertion( ) -AnnotationAssertion( "CALOHA:TS-2374") -AnnotationAssertion( "FMA:72144") -AnnotationAssertion(Annotation( "FMA:72144") "skin melanocyte") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "melanocyte of skin") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) - -# Class: (chromaffin cell of ovary) - -AnnotationAssertion(Annotation( "GOC:tfm") "A chromaffin cell that is part of the ovary.") -AnnotationAssertion( "FMA:74319") -AnnotationAssertion(rdfs:label "chromaffin cell of ovary") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (chromaffin cell of right ovary) - -AnnotationAssertion(Annotation( "GOC:tfm") "A chromaffin cell that is part of the right ovary.") -AnnotationAssertion( "FMA:74320") -AnnotationAssertion(rdfs:label "chromaffin cell of right ovary") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (chromaffin cell of left ovary) - -AnnotationAssertion(Annotation( "GOC:tfm") "A chromaffin cell that is part of the left ovary.") -AnnotationAssertion( "FMA:74321") -AnnotationAssertion(rdfs:label "chromaffin cell of left ovary") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (transitional myocyte of sinoatrial node) - -AnnotationAssertion(Annotation( "GOC:tfm") "A transitional myocyte that is part of the sinoatrial node.") -AnnotationAssertion( "FMA:83384") -AnnotationAssertion( "transitinal myocyte of sinuatrial node") -AnnotationAssertion(rdfs:label "transitional myocyte of sinoatrial node") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (Purkinje myocyte of atrioventricular node) - -AnnotationAssertion(Annotation( "GOC:tfm") "A Purkinje myocyte that is part of the atrioventricular node.") -AnnotationAssertion( "FMA:83386") -AnnotationAssertion(rdfs:label "Purkinje myocyte of atrioventricular node") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (transitional myocyte of internodal tract) - -AnnotationAssertion(Annotation( "GOC:tfm") "A transitional myocyte that is part of the internodal tract.") -AnnotationAssertion( "FMA:83387") -AnnotationAssertion(rdfs:label "transitional myocyte of internodal tract") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (transitional myocyte of atrioventricular bundle) - -AnnotationAssertion(Annotation( "GOC:tfm") "A transitional myocyte that is part of the atrioventricular bundle.") -AnnotationAssertion( "FMA:83388") -AnnotationAssertion( "FMA:83885") -AnnotationAssertion(rdfs:label "transitional myocyte of atrioventricular bundle") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (myocardial endocrine cell of interventricular septum) - -AnnotationAssertion(Annotation( "GOC:tfm") "A myocardial endocrine cell that is part of the interventricular septum.") -AnnotationAssertion( "FMA:83390") -AnnotationAssertion(rdfs:label "myocardial endocrine cell of interventricular septum") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (Purkinje myocyte of internodal tract) - -AnnotationAssertion(Annotation( "GOC:tfm") "A Purkinje myocyte that is part of the internodal tract.") -AnnotationAssertion( "FMA:83392") -AnnotationAssertion(rdfs:label "Purkinje myocyte of internodal tract") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (Purkinje myocyte of atrioventricular bundle) - -AnnotationAssertion(Annotation( "GOC:tfm") "A Purkinje myocyte that is part of the atrioventricular bundle.") -AnnotationAssertion( "FMA:83393") -AnnotationAssertion(rdfs:label "Purkinje myocyte of atrioventricular bundle") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (basal cell of urothelium) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "doi:10.1038/s41385-022-00565-0") "A basal cell that is part of the urothelium. Compared to other urothelial cell types, a basal cell of the urothelium is positioned along the basement membrane, is the most undifferentiated and serves a progenitor role.") -AnnotationAssertion( "FMA:84150") -AnnotationAssertion(Annotation( "doi:10.1007/978-3-030-14366-4_8") Annotation( "doi:10.1111/cpr.13170") "urothelial basal cell") -AnnotationAssertion(Annotation( "doi:10.1038/s41385-022-00565-0") rdfs:comment "It has been noted in at least some mammalian species that the urothelial basal cell type is distinguished by expression of high levels of cytokeratin-5 (CK5), p63 and the signalling molecule Sonic hedgehog (Shh). Similar to intermediate cells, the urothelial basal cell type expresses CK17 but is negative for uroplakins (UPK) and CK20. Urothelial basal cells have also been noted to be smaller in diameter than urothelial intermediate cells.") -AnnotationAssertion(rdfs:label "basal cell of urothelium") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) - # Class: (smooth muscle cell of prostate) AnnotationAssertion(Annotation( "GOC:tfm") "A smooth muscle cell that is part of the prostate gland.") @@ -41798,7 +19607,6 @@ AnnotationAssertion( "FMA:84583") "smooth muscle fiber of prostate") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "smooth muscle cell of prostate") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) # Class: (cholangiocyte) @@ -41807,995 +19615,37 @@ AnnotationAssertion(Annotation( "FMA:86481") AnnotationAssertion( "epithelial cell of bile duct") AnnotationAssertion(rdfs:label "cholangiocyte") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( )))) -# Class: (reticular cell of splenic cord) - -AnnotationAssertion(Annotation( "GOC:tfm") "A reticular cell that is part of the splenic cord.") -AnnotationAssertion( ) -AnnotationAssertion( "FMA:86497") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "reticular cell of splenic cord") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (mesothelial cell of peritoneum) - -AnnotationAssertion(Annotation( "GOC:tfm") "A mesothelial cell that is part of the peritoneum.") -AnnotationAssertion( "FMA:86736") -AnnotationAssertion(Annotation( "FMA:86736") "peritoneal mesothelial cell") -AnnotationAssertion(rdfs:label "mesothelial cell of peritoneum") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) - -# Class: (mesothelial cell of pleura) - -AnnotationAssertion(Annotation( "GOC:tfm") "A mesothelial cell that is part of the pleura.") -AnnotationAssertion( "FMA:86737") -AnnotationAssertion(Annotation( "FMA:86737") "pleural mesothelial cell") -AnnotationAssertion(rdfs:label "mesothelial cell of pleura") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) - -# Class: (mesothelial cell of parietal pleura) - -AnnotationAssertion(Annotation( "GOC:tfm") "A mesothelial cell that is part of the parietal pleura.") -AnnotationAssertion( "FMA:86738") -AnnotationAssertion(rdfs:label "mesothelial cell of parietal pleura") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) - -# Class: (mesothelial cell of visceral pleura) - -AnnotationAssertion(Annotation( "GOC:tfm") "A mesothelial cell that is part of the visceral pleura.") -AnnotationAssertion( "FMA:86739") -AnnotationAssertion(rdfs:label "mesothelial cell of visceral pleura") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (nephron tubule epithelial cell) - -AnnotationAssertion(Annotation( "GOC:tfm") "An epithelial cell that is part of a nephron tubule.") -AnnotationAssertion( "FMA:86785") -AnnotationAssertion( "KUPO:0001022") -AnnotationAssertion( "kidney tubule epithelial cell") -AnnotationAssertion(rdfs:comment "This needs to be further defined as a juxtamedullary nephron. Will request the juxtamedullary nephron tubule class from UBERON.") -AnnotationAssertion(rdfs:label "nephron tubule epithelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (small intestine goblet cell) - -AnnotationAssertion(Annotation( "GOC:tfm") "A goblet cell that is part of the small intestine.") -AnnotationAssertion( "FMA:86929") -AnnotationAssertion( "goblet cell of epithelium of small intestine") -AnnotationAssertion( "goblet cell of small intestine") -AnnotationAssertion(Annotation( "FMA:86929") "small intestinal goblet cell") -AnnotationAssertion(rdfs:label "small intestine goblet cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (kidney cell) AnnotationAssertion( "KUPO:0001010") AnnotationAssertion(rdfs:label "kidney cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (kidney interstitial cell) - -AnnotationAssertion( "KUPO:0001013") -AnnotationAssertion(rdfs:label "kidney interstitial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (kidney medulla cell) - -AnnotationAssertion( "KUPO:0001017") -AnnotationAssertion(rdfs:label "kidney medulla cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (kidney pelvis cell) - -AnnotationAssertion( "KUPO:0001018") -AnnotationAssertion(rdfs:label "kidney pelvis cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (kidney tubule cell) - -AnnotationAssertion( "KUPO:0001020") -AnnotationAssertion(rdfs:label "kidney tubule cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (kidney glomerular epithelial cell) - -AnnotationAssertion( "KUPO:0001023") -AnnotationAssertion(rdfs:label "kidney glomerular epithelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (kidney medulla collecting duct epithelial cell) - -AnnotationAssertion( "KUPO:0001060") -AnnotationAssertion(rdfs:label "kidney medulla collecting duct epithelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (kidney inner medulla collecting duct epithelial cell) - -AnnotationAssertion( "An epithelial cell that is part of some inner medullary collecting duct.") -AnnotationAssertion( "KUPO:0001061") -AnnotationAssertion(rdfs:label "kidney inner medulla collecting duct epithelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (kidney outer medulla collecting duct epithelial cell) - -AnnotationAssertion( "KUPO:0001062") -AnnotationAssertion(rdfs:label "kidney outer medulla collecting duct epithelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (kidney cortex collecting duct epithelial cell) - -AnnotationAssertion( "KUPO:0001063") -AnnotationAssertion(rdfs:label "kidney cortex collecting duct epithelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (kidney papillary duct principal epithelial cell) - -AnnotationAssertion( "KUPO:0001064") -AnnotationAssertion(rdfs:label "kidney papillary duct principal epithelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (inner renal cortex cell) - -AnnotationAssertion( "KUPO:0001111") -AnnotationAssertion(rdfs:label "inner renal cortex cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (papillary tips cell) - -AnnotationAssertion( "A cell that is part of a tip of a renal papilla.") -AnnotationAssertion( ) -AnnotationAssertion( "KUPO:0001112") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "papillary tips cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (lower urinary tract cell) - -AnnotationAssertion( "KUPO:0001115") -AnnotationAssertion(rdfs:label "lower urinary tract cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (ureteral cell) - -AnnotationAssertion( "KUPO:0001116") -AnnotationAssertion(rdfs:label "ureteral cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (kidney nerve cell) - -AnnotationAssertion( "KUPO:0001015") -AnnotationAssertion(rdfs:label "kidney nerve cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (kidney corpuscule cell) - -AnnotationAssertion( "KUPO:0001021") -AnnotationAssertion(rdfs:label "kidney corpuscule cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (kidney cortex tubule cell) - -AnnotationAssertion( "KUPO:0001024") -AnnotationAssertion(rdfs:label "kidney cortex tubule cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (kidney outer medulla cell) - -AnnotationAssertion( "KUPO:0001025") -AnnotationAssertion(rdfs:label "kidney outer medulla cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (kidney inner medulla cell) - -AnnotationAssertion( "KUPO:0001026") -AnnotationAssertion(rdfs:label "kidney inner medulla cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) # Class: (juxtaglomerular complex cell) AnnotationAssertion( "KUPO:0001028") AnnotationAssertion(Annotation( "GO:0072052") "juxtaglomerulus cell") AnnotationAssertion(rdfs:label "juxtaglomerular complex cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (kidney cortex interstitial cell) - -AnnotationAssertion( "KUPO:0001091") -AnnotationAssertion(rdfs:label "kidney cortex interstitial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (kidney medulla interstitial cell) - -AnnotationAssertion( "KUPO:0001092") -AnnotationAssertion(rdfs:label "kidney medulla interstitial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (kidney interstitial fibroblast) AnnotationAssertion( ) AnnotationAssertion( "KUPO:0001102") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "kidney interstitial fibroblast") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (kidney pelvis smooth muscle cell) - -AnnotationAssertion( "KUPO:0001113") -AnnotationAssertion(rdfs:label "kidney pelvis smooth muscle cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (kidney pelvis urothelial cell) - -AnnotationAssertion( "KUPO:0001114") -AnnotationAssertion(rdfs:label "kidney pelvis urothelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (ureter urothelial cell) - -AnnotationAssertion( "KUPO:0001117") -AnnotationAssertion(rdfs:label "ureter urothelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (ureter adventitial cell) - -AnnotationAssertion( ) -AnnotationAssertion( "KUPO:0001119") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "ureter adventitial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (kidney cortex collecting duct principal cell) - -AnnotationAssertion( ) -AnnotationAssertion( "KUPO:0001130") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "kidney cortex collecting duct principal cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (kidney outer medulla collecting duct principal cell) - -AnnotationAssertion(Annotation( "PMID:25632105") "Principal cell that is part of some outer medullary collecting duct. It is known in some mammalian species that this cell may express the epithelial sodium channel (ENaC).") -AnnotationAssertion( ) -AnnotationAssertion( "KUPO:0001132") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "kidney outer medulla collecting duct principal cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (kidney inner medulla collecting duct principal cell) - -AnnotationAssertion( ) -AnnotationAssertion( "KUPO:0001134") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "kidney inner medulla collecting duct principal cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (kidney papillary duct principal cell) - -AnnotationAssertion( "KUPO:0001137") -AnnotationAssertion(rdfs:label "kidney papillary duct principal cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (glomerular cell) - -AnnotationAssertion( "KUPO:0001036") -AnnotationAssertion(rdfs:label "glomerular cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (kidney connecting tubule epithelial cell) - -AnnotationAssertion( ) -AnnotationAssertion( "KUPO:0001058") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "kidney connecting tubule epithelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (kidney inner medulla interstitial cell) - -AnnotationAssertion( "KUPO:0001093") -AnnotationAssertion(rdfs:label "kidney inner medulla interstitial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (kidney outer medulla interstitial cell) - -AnnotationAssertion( "KUPO:0001094") -AnnotationAssertion(rdfs:label "kidney outer medulla interstitial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (kidney proximal convoluted tubule epithelial cell) - -AnnotationAssertion( "KUPO:0001045") -AnnotationAssertion(rdfs:label "kidney proximal convoluted tubule epithelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (kidney proximal straight tubule epithelial cell) - -AnnotationAssertion( "KUPO:0001046") -AnnotationAssertion(rdfs:label "kidney proximal straight tubule epithelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (kidney distal convoluted tubule epithelial cell) - -AnnotationAssertion( ) -AnnotationAssertion( "KUPO:0001056") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "kidney distal convoluted tubule epithelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (macula densa epithelial cell) - -AnnotationAssertion( ) -AnnotationAssertion( "KUPO:0001057") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "macula densa epithelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (kidney blood vessel cell) - -AnnotationAssertion( "KUPO:0001014") -AnnotationAssertion(rdfs:label "kidney blood vessel cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (kidney arterial blood vessel cell) - -AnnotationAssertion( "KUPO:0001029") -AnnotationAssertion(rdfs:label "kidney arterial blood vessel cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (kidney capillary endothelial cell) - -AnnotationAssertion( "KUPO:0001030") -AnnotationAssertion(rdfs:label "kidney capillary endothelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (kidney venous blood vessel cell) - -AnnotationAssertion( "KUPO:0001031") -AnnotationAssertion(rdfs:label "kidney venous blood vessel cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (kidney loop of Henle epithelial cell) - -AnnotationAssertion( "KUPO:0001047") -AnnotationAssertion(rdfs:label "kidney loop of Henle epithelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (ureter smooth muscle cell) - -AnnotationAssertion( "KUPO:0001118") -AnnotationAssertion(rdfs:label "ureter smooth muscle cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (glomerular capillary endothelial cell) - -AnnotationAssertion( ) -AnnotationAssertion( "KUPO:0001037") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "glomerular capillary endothelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (kidney afferent arteriole cell) - -AnnotationAssertion( "KUPO:0001038") -AnnotationAssertion(rdfs:label "kidney afferent arteriole cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (kidney efferent arteriole cell) - -AnnotationAssertion( "KUPO:0001041") -AnnotationAssertion(rdfs:label "kidney efferent arteriole cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (kidney loop of Henle ascending limb epithelial cell) - -AnnotationAssertion( "KUPO:0001048") -AnnotationAssertion(rdfs:label "kidney loop of Henle ascending limb epithelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (kidney loop of Henle descending limb epithelial cell) - -AnnotationAssertion( "KUPO:0001053") -AnnotationAssertion(rdfs:label "kidney loop of Henle descending limb epithelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (peritubular capillary endothelial cell) - -AnnotationAssertion( "An endothelial cell that is part of some peritubular capillary.") -AnnotationAssertion( ) -AnnotationAssertion( "KUPO:0001065") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "peritubular capillary endothelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (vasa recta cell) - -AnnotationAssertion( "KUPO:0001068") -AnnotationAssertion(rdfs:label "vasa recta cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (kidney cortex artery cell) - -AnnotationAssertion( "KUPO:0001077") -AnnotationAssertion(rdfs:label "kidney cortex artery cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (kidney cortex vein cell) - -AnnotationAssertion( "KUPO:0001084") -AnnotationAssertion(rdfs:label "kidney cortex vein cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (kidney artery smooth muscle cell) - -AnnotationAssertion( "KUPO:0001096") -AnnotationAssertion(rdfs:comment "Note that the source of this term is KUPO:0001096 (artery smooth muscle cell), which we believe actually denotes the kidney specific structure.") -AnnotationAssertion(rdfs:label "kidney artery smooth muscle cell") -SubClassOf( ) -SubClassOf( ) - -# Class: (kidney arteriole smooth muscle cell) - -AnnotationAssertion( "KUPO:0001098") -AnnotationAssertion(rdfs:comment "Note that the source of this term is KUPO:0001098 (arteriole smooth muscle cell), which we believe actually denotes the kidney specific structure.") -AnnotationAssertion(rdfs:label "kidney arteriole smooth muscle cell") -SubClassOf( ) -SubClassOf( ) - -# Class: (kidney venous system smooth muscle cell) - -AnnotationAssertion( "KUPO:0001100") -AnnotationAssertion(rdfs:comment "Note that the source of this term is KUPO:0001068 (venous system smooth muscle cell), which we believe actually denotes the kidney specific structure.") -AnnotationAssertion(rdfs:label "kidney venous system smooth muscle cell") -SubClassOf( ) -SubClassOf( ) - -# Class: (kidney afferent arteriole endothelial cell) - -AnnotationAssertion( ) -AnnotationAssertion( "KUPO:0001039") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "kidney afferent arteriole endothelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) -SubClassOf( ) - -# Class: (kidney afferent arteriole smooth muscle cell) - -AnnotationAssertion( "KUPO:0001040") -AnnotationAssertion(rdfs:label "kidney afferent arteriole smooth muscle cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) -SubClassOf( ) - -# Class: (kidney efferent arteriole endothelial cell) - -AnnotationAssertion( ) -AnnotationAssertion( "KUPO:0001042") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "kidney efferent arteriole endothelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) -SubClassOf( ) - -# Class: (kidney efferent arteriole smooth muscle cell) - -AnnotationAssertion( "KUPO:0001043") -AnnotationAssertion(rdfs:label "kidney efferent arteriole smooth muscle cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) -SubClassOf( ) - -# Class: (kidney loop of Henle thick ascending limb epithelial cell) - -AnnotationAssertion(Annotation( "PMID:25318757") "An epithelial cell that is part of some loop of Henle thick ascending limb. It is known in some mammalian species that this cell may express the Na+-K+-2Cl− cotransporter (NKCC2) apically.") -AnnotationAssertion( ) -AnnotationAssertion( "KUPO:0001049") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "kidney loop of Henle thick ascending limb epithelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (kidney loop of Henle thin ascending limb epithelial cell) - -AnnotationAssertion( "An epithelial cell that is part of some loop of Henle thin ascending limb.") -AnnotationAssertion( ) -AnnotationAssertion( "KUPO:0001050") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "kidney loop of Henle thin ascending limb epithelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (kidney loop of Henle medullary thick ascending limb epithelial cell) - -AnnotationAssertion( "An epithelial cell that is part of some loop of Henle thick ascending limb segment located in the renal medulla.") -AnnotationAssertion( ) -AnnotationAssertion( "KUPO:0001051") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "kidney loop of Henle medullary thick ascending limb epithelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (kidney loop of Henle cortical thick ascending limb epithelial cell) - -AnnotationAssertion( "An epithelial cell that is part of some loop of Henle thick ascending limb segment located in the renal cortex.") -AnnotationAssertion( ) -AnnotationAssertion( "KUPO:0001052") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "kidney loop of Henle cortical thick ascending limb epithelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (kidney loop of Henle thin descending limb epithelial cell) - -AnnotationAssertion( "An epithelial cell that is part of some loop of Henle thin descending limb.") -AnnotationAssertion( ) -AnnotationAssertion( "KUPO:0001054") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "kidney loop of Henle thin descending limb epithelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (kidney outer medulla peritubular capillary cell) - -AnnotationAssertion( "KUPO:0001066") -AnnotationAssertion(rdfs:label "kidney outer medulla peritubular capillary cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (kidney cortex peritubular capillary cell) - -AnnotationAssertion( "KUPO:0001067") -AnnotationAssertion(rdfs:label "kidney cortex peritubular capillary cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (inner renal medulla vasa recta cell) - -AnnotationAssertion( "KUPO:0001069") -AnnotationAssertion(rdfs:label "inner renal medulla vasa recta cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (outer renal medulla vasa recta cell) - -AnnotationAssertion( "KUPO:0001070") -AnnotationAssertion(rdfs:label "outer renal medulla vasa recta cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (vasa recta ascending limb cell) - -AnnotationAssertion( "A cell that is part of some vasa recta ascending limb.") -AnnotationAssertion( ) -AnnotationAssertion( "KUPO:0001074") -AnnotationAssertion( ) -AnnotationAssertion(Annotation( "PMID:20392798") Annotation( "PMID:20392799") Annotation( "PMID:26062876") rdfs:comment "It is known in some mammalian species that this cell may express PV-1, a component of the fenestral diaphragm.") -AnnotationAssertion(rdfs:label "vasa recta ascending limb cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (arcuate artery cell) - -AnnotationAssertion( "KUPO:0001078") -AnnotationAssertion(rdfs:label "arcuate artery cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (interlobular artery cell) - -AnnotationAssertion( "KUPO:0001081") -AnnotationAssertion(rdfs:label "interlobular artery cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (arcuate vein cell) - -AnnotationAssertion( "KUPO:0001085") -AnnotationAssertion(rdfs:label "arcuate vein cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (interlobular vein cell) - -AnnotationAssertion( "KUPO:0001088") -AnnotationAssertion(rdfs:label "interlobular vein cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (inner medulla vasa recta ascending limb cell) - -AnnotationAssertion( "KUPO:0001075") -AnnotationAssertion(rdfs:label "inner medulla vasa recta ascending limb cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (outer medulla vasa recta ascending limb cell) - -AnnotationAssertion( "KUPO:0001076") -AnnotationAssertion(rdfs:label "outer medulla vasa recta ascending limb cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (arcuate artery endothelial cell) - -AnnotationAssertion( "KUPO:0001079") -AnnotationAssertion(rdfs:label "arcuate artery endothelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) -SubClassOf( ) - -# Class: (arcuate artery smooth muscle cell) - -AnnotationAssertion( "KUPO:0001080") -AnnotationAssertion(rdfs:label "arcuate artery smooth muscle cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) -SubClassOf( ) - -# Class: (interlobulary artery endothelial cell) - -AnnotationAssertion( "KUPO:0001082") -AnnotationAssertion(rdfs:label "interlobulary artery endothelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (interlobulary artery smooth muscle cell) - -AnnotationAssertion( "KUPO:0001083") -AnnotationAssertion(rdfs:label "interlobulary artery smooth muscle cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) -SubClassOf( ) - -# Class: (arcuate vein endothelial cell) - -AnnotationAssertion( "KUPO:0001086") -AnnotationAssertion(rdfs:label "arcuate vein endothelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (arcuate vein smooth muscle cell) - -AnnotationAssertion( "KUPO:0001087") -AnnotationAssertion(rdfs:label "arcuate vein smooth muscle cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) -SubClassOf( ) - -# Class: (interlobulary vein endothelial cell) - -AnnotationAssertion( "KUPO:0001089") -AnnotationAssertion(rdfs:label "interlobulary vein endothelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (interlobulary vein smooth muscle cell) - -AnnotationAssertion( "KUPO:0001090") -AnnotationAssertion(rdfs:label "interlobulary vein smooth muscle cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) -SubClassOf( ) - -# Class: (kidney collecting duct cell) - -AnnotationAssertion( "KUPO:0001012") -AnnotationAssertion( "Wikipedia:Kidney_collecting_duct_cell") -AnnotationAssertion(rdfs:label "kidney collecting duct cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (vasa recta descending limb cell) - -AnnotationAssertion( "A cell that is part of some vasa recta descending limb.") -AnnotationAssertion( ) -AnnotationAssertion( "KUPO:0001071") -AnnotationAssertion( ) -AnnotationAssertion(Annotation( "PMID:20392798") Annotation( "PMID:20392799") Annotation( "PMID:26062876") rdfs:comment "It is known in some mammalian species that this cell may express the urea transporter B.") -AnnotationAssertion(rdfs:label "vasa recta descending limb cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (inner medulla vasa recta descending limb cell) - -AnnotationAssertion( "KUPO:0001072") -AnnotationAssertion(rdfs:label "inner medulla vasa recta descending limb cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (outer medulla vasa recta descending limb cell) - -AnnotationAssertion( "KUPO:0001073") -AnnotationAssertion(rdfs:label "outer medulla vasa recta descending limb cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (renal interstitial pericyte) - -AnnotationAssertion( "A pericyte cell located in the kidney interstitium.") -AnnotationAssertion( ) -AnnotationAssertion( "KUPO:0001104") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "renal interstitial pericyte") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) - -# Class: (bladder cell) - -AnnotationAssertion( ) -AnnotationAssertion( "KUPO:0001120") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "bladder cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (urethra cell) - -AnnotationAssertion( "KUPO:0001123") -AnnotationAssertion(rdfs:label "urethra cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (bladder urothelial cell) - -AnnotationAssertion(Annotation( "doi:10.1038/s41385-022-00565-0") "A urothelial cell that is part of the urothelium of the urinary bladder.") -AnnotationAssertion( ) -AnnotationAssertion( "KUPO:0001121") -AnnotationAssertion( "NCIT:C32210") -AnnotationAssertion( "bladder transitional cell") -AnnotationAssertion( "transitional epithelial cell of urinary bladder") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "bladder urothelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (urethra urothelial cell) - -AnnotationAssertion( "KUPO:0001124") -AnnotationAssertion(rdfs:label "urethra urothelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (kidney collecting duct principal cell) - -AnnotationAssertion( ) -AnnotationAssertion( "KUPO:0001128") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "kidney collecting duct principal cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (epithelial cell of exocrine pancreas) - -AnnotationAssertion(Annotation( "GOC:tfm") "An epithelial cell of the exocrine pancreas.") -AnnotationAssertion( ) -AnnotationAssertion( "FMA:70986") -AnnotationAssertion( "exocrine pancreas cell") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "epithelial cell of exocrine pancreas") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (olfactory bulb interneuron) AnnotationAssertion(Annotation( "PMID:18603310") "A neuron residing in the olfactory bulb that serve to process and refine signals arising from olfactory sensory neurons") AnnotationAssertion(rdfs:label "olfactory bulb interneuron") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (sensory neuron of dorsal root ganglion) - -AnnotationAssertion(Annotation( "MP:0004297") "A sensory neuron of the dorsal root ganglia that senses body position and sends information about how much the muscle is stretched to the spinal cord.") -AnnotationAssertion(Annotation( "MP:0004297") "proprioceptive neuron") -AnnotationAssertion(rdfs:label "sensory neuron of dorsal root ganglion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (mitral cell) AnnotationAssertion(Annotation( "MP:0009954") "The large glutaminergic nerve cells whose dendrites synapse with axons of the olfactory receptor neurons in the glomerular layer of the olfactory bulb, and whose axons pass centrally in the olfactory tract to the olfactory cortex.") @@ -42820,1147 +19670,6 @@ SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (intestinal enteroendocrine cell) - -AnnotationAssertion(Annotation( "MP:0010802") "The various hormone- or neurotransmitter-secreting cells present throughout the mucosa of the intestinal tract.") -AnnotationAssertion(rdfs:label "intestinal enteroendocrine cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (stomach enteroendocrine cell) - -AnnotationAssertion(Annotation( "MP:0010803") "The various hormone- or neurotransmitter-secreting cells present throughout the mucosa of the stomach.") -AnnotationAssertion(rdfs:label "stomach enteroendocrine cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (lung endothelial cell) - -AnnotationAssertion( ) -AnnotationAssertion( "endothelial cell of lung") -AnnotationAssertion( "pulmonary vessel endothelial cell") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "lung endothelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (pulmonary artery endothelial cell) - -AnnotationAssertion( "BTO:0001141") -AnnotationAssertion(Annotation( "BTO:0001141") "PAEC cell") -AnnotationAssertion(rdfs:label "pulmonary artery endothelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (hippocampal interneuron) - -AnnotationAssertion(Annotation( "GOC:pr") "An interneuron with a soma found in the hippocampus.") -AnnotationAssertion( "FMA:84777") -AnnotationAssertion(rdfs:label "hippocampal interneuron") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (hippocampal pyramidal neuron) - -AnnotationAssertion(Annotation( "GOC:pr") Annotation( "PMID:19342486") "A pyramidal neuron with a soma found in the hippocampus.") -AnnotationAssertion( "NIFSTD:sao131261273") -AnnotationAssertion( "SAO:sao131261273") -AnnotationAssertion(Annotation( "NIFSTD:sao131261273") "hippocampus (CA) pyramidal cell") -AnnotationAssertion(Annotation( "NIFSTD:sao131261273") "hippocampus (CA) pyramidal neuron") -AnnotationAssertion(rdfs:label "hippocampal pyramidal neuron") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (colon endothelial cell) - -AnnotationAssertion(Annotation( "NPX:PDR") Annotation( "https://orcid.org/0000-0001-5208-3432") "A vascular endothelial cell found in colon blood vessels.") -AnnotationAssertion( "CALOHA:TS-2397") -AnnotationAssertion(Annotation( "CALOHA:TS-2397") Annotation( ) "colon endothelial cells") -AnnotationAssertion(Annotation( "CALOHA:TS-2397") "colonic endothelial cell") -AnnotationAssertion(rdfs:label "colon endothelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (nasopharyngeal epithelial cell) - -AnnotationAssertion(Annotation( "NPX:PDR") "Cell of the nasopharyngeal epithelium.") -AnnotationAssertion( "CALOHA:TS-2398") -AnnotationAssertion(Annotation( "CALOHA:TS-2398") "nasopharynx respiratory epithelial cells") -AnnotationAssertion(rdfs:label "nasopharyngeal epithelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (uterine cervix squamous cell) - -AnnotationAssertion(Annotation( "NPX:PDR") "Squamous cell of uterine cervix epithelium.") -AnnotationAssertion( "CALOHA:TS-1251") -AnnotationAssertion(Annotation( "CALOHA:TS-1251") "cervix squamous cell") -AnnotationAssertion(Annotation( "CALOHA:TS-1251") "cervix squamous epithelial cell") -AnnotationAssertion(Annotation( "CALOHA:TS-1251") "cervix, uterine squamous epithelial cells") -AnnotationAssertion(Annotation( "CALOHA:TS-1251") "uterine cervix squamous epithelial cell") -AnnotationAssertion(Annotation( "CALOHA:TS-1251") "uterine cervix squamous epithelial cells") -AnnotationAssertion(rdfs:label "uterine cervix squamous cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (oral mucosa squamous cell) - -AnnotationAssertion(Annotation( "NPX:PDR") "Squamous cell of oral epithelium.") -AnnotationAssertion( "CALOHA:TS-1252") -AnnotationAssertion(Annotation( "CALOHA:TS-1252") "oral cavity mucosa squamous cell") -AnnotationAssertion(Annotation( "CALOHA:TS-1252") "oral cavity mucosa squamous epithelial cell") -AnnotationAssertion(Annotation( "CALOHA:TS-1252") "oral mucosa squamous epithelial cell") -AnnotationAssertion(Annotation( "CALOHA:TS-1252") "oral mucosa squamous epithelial cells") -AnnotationAssertion(rdfs:label "oral mucosa squamous cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (tonsil squamous cell) - -AnnotationAssertion(Annotation( "NPX:PDR") "Squamous cell of tonsil epithelium.") -AnnotationAssertion( ) -AnnotationAssertion( "CALOHA:TS-1253") -AnnotationAssertion(Annotation( "CALOHA:TS-1253") "tonsil squamous epithelial cell") -AnnotationAssertion(Annotation( "CALOHA:TS-1253") "tonsil squamous epithelial cells") -AnnotationAssertion(Annotation( "CALOHA:TS-1253") "tonsillar squamous cell") -AnnotationAssertion(Annotation( "CALOHA:TS-1253") "tonsillar squamous epithelial cell") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "tonsil squamous cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (vagina squamous cell) - -AnnotationAssertion(Annotation( "NPX:PDR") "Squamous cell of vaginal epithelium.") -AnnotationAssertion( "CALOHA:TS-1254") -AnnotationAssertion(Annotation( "CALOHA:TS-1254") "vagina squamous epithelial cell") -AnnotationAssertion(Annotation( "CALOHA:TS-1254") "vagina squamous epithelial cells") -AnnotationAssertion(Annotation( "CALOHA:TS-1254") "vaginal squamous cell") -AnnotationAssertion(Annotation( "CALOHA:TS-1254") "vaginal squamous epithelial cell") -AnnotationAssertion(rdfs:label "vagina squamous cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cerebral cortex glial cell) - -AnnotationAssertion(Annotation( "NPX:PDR") "Glial cell of cerebral cortex.") -AnnotationAssertion( "CALOHA:TS-1256") -AnnotationAssertion(Annotation( "CALOHA:TS-1256") "brain cortex glial cell") -AnnotationAssertion(Annotation( "CALOHA:TS-1256") "cerebral cortex glial cells") -AnnotationAssertion(Annotation( "CALOHA:TS-1256") "cerebrum cortex glial cell") -AnnotationAssertion(rdfs:label "cerebral cortex glial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (hippocampal glial cell) - -AnnotationAssertion(Annotation( "NPX:PDR") "A glial cell that is part of the hippocampus.") -AnnotationAssertion( "CALOHA:TS-1257") -AnnotationAssertion(Annotation( "CALOHA:TS-1257") "hippocampus glial cell") -AnnotationAssertion(Annotation( "CALOHA:TS-1257") "hippocampus neuroglial cell") -AnnotationAssertion(rdfs:label "hippocampal glial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (lateral ventricle glial cell) - -AnnotationAssertion(Annotation( "NPX:PDR") "Glial cell of lateral ventricle.") -AnnotationAssertion( "CALOHA:TS-1258") -AnnotationAssertion(Annotation( "CALOHA:TS-1258") "lateral ventricle glial cells") -AnnotationAssertion(rdfs:label "lateral ventricle glial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (lateral ventricle neuron) - -AnnotationAssertion(Annotation( "NPX:PDR") "Neuron of lateral ventricle.") -AnnotationAssertion( "CALOHA:TS-1261") -AnnotationAssertion(Annotation( "CALOHA:TS-1261") "lateral ventricle neural cell") -AnnotationAssertion(Annotation( "CALOHA:TS-1261") "lateral ventricle neuronal cell") -AnnotationAssertion(Annotation( "CALOHA:TS-1261") "lateral ventricle neuronal cells") -AnnotationAssertion(rdfs:label "lateral ventricle neuron") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (appendix glandular cell) - -AnnotationAssertion(Annotation( "NPX:PDR") "Glandular cell of appendix epithelium. Example: Goblet cells; enterocytes or absorptive cells; enteroendocrine and M cells.") -AnnotationAssertion( "CALOHA:TS-1271") -AnnotationAssertion(Annotation( "CALOHA:TS-1271") "appendix glandular cells") -AnnotationAssertion(Annotation( "CALOHA:TS-1271") "caecal appendix glandular cell") -AnnotationAssertion(Annotation( "CALOHA:TS-1271") "cecal appendix glandular cell") -AnnotationAssertion(Annotation( "CALOHA:TS-1271") "vermiform appendix glandular cell") -AnnotationAssertion(rdfs:label "appendix glandular cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (mammary gland glandular cell) - -AnnotationAssertion(Annotation( "HPA:HPA") Annotation( "NPX:PDR") "Glandular cell of mammary epithelium. Example: glandular cells of large and intermediate ducts, glandular cells in terminal ducts.") -AnnotationAssertion( "CALOHA:TS-1272") -AnnotationAssertion(Annotation( "CALOHA:TS-1272") "breast glandular cell") -AnnotationAssertion(Annotation( "CALOHA:TS-1272") "breast glandular cells") -AnnotationAssertion(Annotation( "CALOHA:TS-1272") "mammary glandular cell") -AnnotationAssertion(rdfs:label "mammary gland glandular cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (uterine cervix glandular cell) - -AnnotationAssertion(Annotation( "NPX:PDR") "Glandular cell of uterine cervix epithelium.") -AnnotationAssertion( "CALOHA:TS-1273") -AnnotationAssertion(Annotation( "CALOHA:TS-1273") "cervix glandular cell") -AnnotationAssertion(Annotation( "CALOHA:TS-1273") "cervix, uterine glandular cell") -AnnotationAssertion(Annotation( "CALOHA:TS-1273") "cervix, uterine glandular cells") -AnnotationAssertion(rdfs:label "uterine cervix glandular cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (colon glandular cell) - -AnnotationAssertion(Annotation( "NPX:PDR") "Glandular cell of colon epithelium. Example: Goblet cells; enterocytes or absorptive cells; enteroendocrine and M cells.") -AnnotationAssertion( "CALOHA:TS-1274") -AnnotationAssertion(Annotation( "CALOHA:TS-1274") "colon glandular cells") -AnnotationAssertion(rdfs:label "colon glandular cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (duodenum glandular cell) - -AnnotationAssertion(Annotation( "NPX:PDR") "Glandular cell of duodenal epithelium. Example: Enterocytes, Goblet cells, enteroendocrine cells; Paneth cells; M cells; Brunner's gland cell.") -AnnotationAssertion( "CALOHA:TS-1275") -AnnotationAssertion(Annotation( "CALOHA:TS-1275") "duodenum glandular cells") -AnnotationAssertion(rdfs:label "duodenum glandular cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (epididymis glandular cell) - -AnnotationAssertion(Annotation( "NPX:PDR") "Glandular cell of epididymal epithelium.") -AnnotationAssertion( "CALOHA:TS-1276") -AnnotationAssertion(Annotation( "CALOHA:TS-1276") "epididymal glandular cell") -AnnotationAssertion(Annotation( "CALOHA:TS-1276") "epididymis glandular cells") -AnnotationAssertion(rdfs:label "epididymis glandular cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (oviduct glandular cell) - -AnnotationAssertion(Annotation( "HPA:HPA") Annotation( "NPX:PDR") "Glandular cell of oviduct epithelium. Example: peg cells, ciliated cells.") -AnnotationAssertion( "CALOHA:TS-1277") -AnnotationAssertion(Annotation( "CALOHA:TS-1277") "fallopian tube glandular cell") -AnnotationAssertion(Annotation( "CALOHA:TS-1277") "fallopian tube glandular cells") -AnnotationAssertion(Annotation( "CALOHA:TS-1277") "uterine tube glandular cell") -AnnotationAssertion(rdfs:label "oviduct glandular cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (gallbladder glandular cell) - -AnnotationAssertion(Annotation( "NPX:PDR") "Glandular cell of gallbladder epithelium.") -AnnotationAssertion( "CALOHA:TS-1278") -AnnotationAssertion(Annotation( "FMA:7202") "gall bladder glandular cell") -AnnotationAssertion(Annotation( "CALOHA:TS-1278") "gall bladder glandular cells") -AnnotationAssertion(Annotation( "CALOHA:TS-1278") "gallbladder glandular cells") -AnnotationAssertion(rdfs:label "gallbladder glandular cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (parathyroid glandular cell) - -AnnotationAssertion(Annotation( "HPA:HPA") Annotation( "NPX:PDR") "Glandular cell of parathyroid epithelium. Example: Parathyroid chief cell and parathyroid oxyphil cells.") -AnnotationAssertion( "CALOHA:TS-1279") -AnnotationAssertion(Annotation( "CALOHA:TS-1279") "parathyroid gland glandular cell") -AnnotationAssertion(Annotation( "CALOHA:TS-1279") "parathyroid gland glandular cells") -AnnotationAssertion(rdfs:label "parathyroid glandular cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (rectum glandular cell) - -AnnotationAssertion(Annotation( "NPX:PDR") "Glandular cell of rectal epithelium. Example: Goblet cell; enterocytes or absorptive cells; enteroendocrine and M cells.") -AnnotationAssertion( "CALOHA:TS-1281") -AnnotationAssertion(Annotation( "CALOHA:TS-1281") "rectal glandular cell") -AnnotationAssertion(Annotation( "CALOHA:TS-1281") "rectum glandular cells") -AnnotationAssertion(rdfs:label "rectum glandular cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (salivary gland glandular cell) - -AnnotationAssertion(Annotation( "HPA:HPA") Annotation( "NPX:PDR") "Glandular cell of salivary gland. Example: Serous cells, mucous cells, cuboidal epithelial cells of the intercalated ducts, simple cuboidal epithelium of the striated ducts, epithelial cells of excretory ducts.") -AnnotationAssertion( "CALOHA:TS-1282") -AnnotationAssertion(Annotation( "CALOHA:TS-1282") "salivary gland glandular cells") -AnnotationAssertion(rdfs:label "salivary gland glandular cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (seminal vesicle glandular cell) - -AnnotationAssertion(Annotation( "NPX:PDR") "Glandular cell of seminal vesicle epithelium.") -AnnotationAssertion( "CALOHA:TS-1283") -AnnotationAssertion(Annotation( "CALOHA:TS-1283") "seminal vesicle glandular cells") -AnnotationAssertion(rdfs:label "seminal vesicle glandular cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (small intestine glandular cell) - -AnnotationAssertion(Annotation( "NCI_Thesaurus:Small_Intestinal_Glandular_Cell") Annotation( "NPX:PDR") "A glandular cell found in the epithelium of the small intestine. Example: Enterocytes, Goblet cells, enteroendocrine cells; Paneth cells; M cells; Somatostatin-secreting Cells (D-cells) .") -AnnotationAssertion( "CALOHA:TS-1286") -AnnotationAssertion( "FMA:86928") -AnnotationAssertion(Annotation( "CALOHA:TS-1286") "small bowel glandular cell") -AnnotationAssertion(Annotation( "CALOHA:TS-1286") "small intestinal glandular cell") -AnnotationAssertion(Annotation( "CALOHA:TS-1286") "small intestine glandular cells") -AnnotationAssertion(rdfs:label "small intestine glandular cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (pancreas exocrine glandular cell) - -AnnotationAssertion(Annotation( "HPA:HPA") Annotation( "NPX:PDR") "Glandular cell of exocrine pancreas epithelium. Example: pancreatic acinar cell, glandular cells in pancreatic canaliculi, glandular cells in pancreatic ducts.") -AnnotationAssertion( ) -AnnotationAssertion( "BTO:0000028") -AnnotationAssertion( "CALOHA:TS-1242") -AnnotationAssertion(Annotation( "CALOHA:TS-1242") "exocrine pancreas glandular cell") -AnnotationAssertion(Annotation( "CALOHA:TS-1242") "pancreas exocrine glandular cells") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "pancreas exocrine glandular cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (adrenal gland glandular cell) - -AnnotationAssertion(Annotation( "NPX:PDR") "Hormone secreting cell located in the cortex of adrenal gland. Glandular cells in the adrenal cortex secrete mineralocorticoids, glucocorticoids and androgens.") -AnnotationAssertion( "CALOHA:TS-2177") -AnnotationAssertion(Annotation( "CALOHA:TS-2177") "adrenal gland glandular cells") -AnnotationAssertion(Annotation( "CALOHA:TS-2177") "adrenal glandular cell") -AnnotationAssertion(Annotation( "CALOHA:TS-2177") "suprarenal gland glandular cell") -AnnotationAssertion(rdfs:label "adrenal gland glandular cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cerebral cortex endothelial cell) - -AnnotationAssertion(Annotation( "NPX:PDR") "Endothelial cells forming the walls of the capillaries within the cerebral cortex.") -AnnotationAssertion( "CALOHA:TS-2372") -AnnotationAssertion(Annotation( "CALOHA:TS-2372") "cerebral cortex endothelial cells") -AnnotationAssertion(Annotation( "CALOHA:TS-2372") "endothelial cells of cerebral cortex") -AnnotationAssertion(rdfs:label "cerebral cortex endothelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (lung macrophage) - -AnnotationAssertion(Annotation( "HPA:HPA") Annotation( "NPX:PDR") "Circulating macrophages and tissue macrophages (alveolar macrophages) of lung.") -AnnotationAssertion( "CALOHA:TS-0576") -AnnotationAssertion(Annotation( "CALOHA:TS-0576") "lung macrophages") -AnnotationAssertion(rdfs:label "lung macrophage") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (foreskin keratinocyte) - -AnnotationAssertion(Annotation( "NPX:PDR") "Keratinocyte from foreskin.") -AnnotationAssertion( "CALOHA:TS-0385") -AnnotationAssertion(rdfs:label "foreskin keratinocyte") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (articular chondrocyte) - -AnnotationAssertion(Annotation( "NPX:PDR") "Chondrocyte forming the hyaline cartilage found in joints.") -AnnotationAssertion( "CALOHA:TS-0056") -AnnotationAssertion(rdfs:label "articular chondrocyte") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (foreskin fibroblast) - -AnnotationAssertion(Annotation( "NPX:PDR") "Fibroblast from foreskin.") -AnnotationAssertion( "CALOHA:TS-0384") -AnnotationAssertion( "BJ fibroblast") -AnnotationAssertion(rdfs:label "foreskin fibroblast") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (muscle fibroblast) - -AnnotationAssertion(Annotation( "NPX:PDR") "Fibroblast from muscle organ.") -AnnotationAssertion( "CALOHA:TS-0643") -AnnotationAssertion(rdfs:label "muscle fibroblast") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (bone marrow hematopoietic cell) - -AnnotationAssertion(Annotation( "NPX:PDR") "Hematopoietic cells resident in the bone marrow. Include: hematopoietic stem cells (lymphoid stem cells and myeloid stem cells) and the precursor cells for thrombocytes, erythrocytes, basophils, neutrophils, eosinophils, monocytes and lymphocytes.") -AnnotationAssertion( "CALOHA:TS-2109") -AnnotationAssertion(Annotation( "CALOHA:TS-2109") "bone marrow hematopoietic cells") -AnnotationAssertion(Annotation( "CALOHA:TS-2109") "bone marrow poietic cells") -AnnotationAssertion(rdfs:label "bone marrow hematopoietic cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cerebellar neuron) - -AnnotationAssertion(Annotation( "NPX:PDR") "Neuron of the cerebellum.") -AnnotationAssertion( "CALOHA:TS-2359") -AnnotationAssertion( "FMA:84665") -AnnotationAssertion(Annotation( "CALOHA:TS-2359") "cerebellum neuron") -AnnotationAssertion(rdfs:label "cerebellar neuron") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (epidermal melanocyte) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any melanocyte that is part of a epidermis.") -AnnotationAssertion( ) -AnnotationAssertion( "2014-02-03T23:03:09Z") -AnnotationAssertion( "CL:2000000") -AnnotationAssertion(rdfs:comment "These cells are found primarily, but not exclusively, in primates including humans") -AnnotationAssertion(rdfs:label "epidermal melanocyte") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (peripheral blood mononuclear cell) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "A leukocyte with a single non-segmented nucleus in the mature form found in the circulatory pool of blood.") -AnnotationAssertion( ) -AnnotationAssertion( "2014-02-11T17:29:04Z") -AnnotationAssertion( "CL:2000001") -AnnotationAssertion(rdfs:label "peripheral blood mononuclear cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (decidual cell) - -AnnotationAssertion(Annotation( "BTO:0002770") Annotation( "NCIT:C32429") Annotation( "PMID:30013421") Annotation( "PMID:30429548") Annotation( "Wiki:Decidual_cells&oldid=937509751") Annotation( "Wiki:Decidualization&oldid=908981933") "A specialized, enlarged, connective tissue cell of the decidua with enlarged nucleus, dense membrane‐bound secretory granules and cytoplasmic accumulation of glycogen and lipid droplets. These cells develop by the transformation of endometrial stromal cells during decidualization.") -AnnotationAssertion( "2014-02-20T23:06:41Z") -AnnotationAssertion( "BTO:0002770") -AnnotationAssertion( "BTO:0005756") -AnnotationAssertion( "NCIT:C32429") -AnnotationAssertion(Annotation( "BTO:0002770") Annotation( "NCIT:C32429") "decidua cell") -AnnotationAssertion(Annotation( "BTO:0005756") Annotation( "PMID:11719592") "decidual stromal cell") -AnnotationAssertion( "CL:2000002") -AnnotationAssertion(rdfs:label "decidual cell") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (pituitary gland cell) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any cell that is part of a pituitary gland.") -AnnotationAssertion( ) -AnnotationAssertion( "2014-03-26T22:14:56Z") -AnnotationAssertion( "CL:2000004") -AnnotationAssertion(rdfs:label "pituitary gland cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (brain macroglial cell) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any macroglial cell that is part of a brain.") -AnnotationAssertion( ) -AnnotationAssertion( "2014-03-28T21:35:27Z") -AnnotationAssertion( "CL:2000005") -AnnotationAssertion(rdfs:label "brain macroglial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (tonsil germinal center B cell) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any germinal center B cell that is part of a tonsil.") -AnnotationAssertion( ) -AnnotationAssertion( "2014-03-28T21:35:33Z") -AnnotationAssertion( "CL:2000006") -AnnotationAssertion(rdfs:label "tonsil germinal center B cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (articular chondrocyte of knee joint) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Chondrocyte forming the hyaline cartilage found in the knee joint.") -AnnotationAssertion( ) -AnnotationAssertion( "2014-06-04T14:40:11Z") -AnnotationAssertion( "CL:2000007") -AnnotationAssertion(rdfs:label "articular chondrocyte of knee joint") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (microvascular endothelial cell) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any blood vessel endothelial cell that is part of a microvascular endothelium.") -AnnotationAssertion( ) -AnnotationAssertion( "2014-06-04T15:07:42Z") -AnnotationAssertion( "CL:2000008") -AnnotationAssertion(rdfs:label "microvascular endothelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (dermis blood vessel endothelial cell) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any blood vessel endothelial cell that is part of a dermis.") -AnnotationAssertion( ) -AnnotationAssertion( "2014-06-04T15:12:06Z") -AnnotationAssertion( "CL:2000010") -AnnotationAssertion(rdfs:label "dermis blood vessel endothelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (dermis lymphatic vessel endothelial cell) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any endothelial cell of lymphatic vessel that is part of a dermis.") -AnnotationAssertion( ) -AnnotationAssertion( "2014-06-04T15:15:08Z") -AnnotationAssertion( "CL:2000011") -AnnotationAssertion(rdfs:label "dermis lymphatic vessel endothelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (fibroblast of pedal digit skin) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any skin fibroblast that is part of a pedal digit skin.") -AnnotationAssertion( ) -AnnotationAssertion( "2014-06-04T15:16:44Z") -AnnotationAssertion( "CL:2000012") -AnnotationAssertion(rdfs:label "fibroblast of pedal digit skin") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (fibroblast of skin of abdomen) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any skin fibroblast that is part of a skin of abdomen.") -AnnotationAssertion( ) -AnnotationAssertion( "2014-06-04T15:18:16Z") -AnnotationAssertion( "CL:2000013") -AnnotationAssertion(rdfs:label "fibroblast of skin of abdomen") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (fibroblast of upper leg skin) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any skin fibroblast that is part of a upper leg skin.") -AnnotationAssertion( ) -AnnotationAssertion( "2014-06-04T15:19:44Z") -AnnotationAssertion( "CL:2000014") -AnnotationAssertion(rdfs:label "fibroblast of upper leg skin") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (fibroblast of arm) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any skin fibroblast that is part of a arm.") -AnnotationAssertion( ) -AnnotationAssertion( "2014-06-04T15:29:06Z") -AnnotationAssertion( "CL:2000015") -AnnotationAssertion(rdfs:label "fibroblast of arm") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (lung microvascular endothelial cell) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any lung endothelial cell that is part of a microvascular endothelium.") -AnnotationAssertion( ) -AnnotationAssertion( "2014-06-04T16:00:56Z") -AnnotationAssertion( "CL:2000016") -AnnotationAssertion(rdfs:label "lung microvascular endothelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (fibroblast of peridontal ligament) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any fibroblast that is part of a periodontal ligament.") -AnnotationAssertion( ) -AnnotationAssertion( "2014-06-04T16:50:33Z") -AnnotationAssertion( "CL:2000017") -AnnotationAssertion(rdfs:label "fibroblast of peridontal ligament") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (endothelial cell of coronary artery) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any endothelial cell of artery that is part of a coronary artery.") -AnnotationAssertion( ) -AnnotationAssertion( "2014-06-04T17:08:47Z") -AnnotationAssertion( "CL:2000018") -AnnotationAssertion(rdfs:label "endothelial cell of coronary artery") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (compound eye photoreceptor cell) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any photoreceptor cell that is part of a compound eye.") -AnnotationAssertion( ) -AnnotationAssertion( "2014-06-24T23:16:45Z") -AnnotationAssertion( "FBbt:00004211") -AnnotationAssertion( "CL:2000019") -AnnotationAssertion(rdfs:label "compound eye photoreceptor cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (inner cell mass cell) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any native cell that is part of a inner cell mass.") -AnnotationAssertion( ) -AnnotationAssertion( "2014-06-24T23:16:53Z") -AnnotationAssertion( "CL:2000020") -AnnotationAssertion(rdfs:label "inner cell mass cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (sebaceous gland cell) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any native cell that is part of a sebaceous gland.") -AnnotationAssertion( ) -AnnotationAssertion( "2014-06-24T23:17:00Z") -AnnotationAssertion( "CL:2000021") -AnnotationAssertion(rdfs:label "sebaceous gland cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (cardiac septum cell) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any native cell that is part of a cardiac septum.") -AnnotationAssertion( ) -AnnotationAssertion( "2014-06-24T23:17:07Z") -AnnotationAssertion( "CL:2000022") -AnnotationAssertion(rdfs:label "cardiac septum cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (spinal cord ventral column interneuron) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any interneuron that is part of a spinal cord ventral column.") -AnnotationAssertion( ) -AnnotationAssertion( "2014-06-25T00:23:36Z") -AnnotationAssertion( "CL:2000023") -AnnotationAssertion(rdfs:label "spinal cord ventral column interneuron") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (spinal cord medial motor column neuron) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any neuron that is part of a spinal cord medial motor column.") -AnnotationAssertion( ) -AnnotationAssertion( "2014-06-25T00:23:43Z") -AnnotationAssertion( "CL:2000024") -AnnotationAssertion(rdfs:label "spinal cord medial motor column neuron") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (spinal cord oligodendrocyte) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any oligodendrocyte that is part of a spinal cord.") -AnnotationAssertion( ) -AnnotationAssertion( "2014-06-25T00:23:50Z") -AnnotationAssertion( "CL:2000025") -AnnotationAssertion(rdfs:label "spinal cord oligodendrocyte") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cerebellum basket cell) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any basket cell that is part of a cerebellum.") -AnnotationAssertion( ) -AnnotationAssertion( "2014-06-25T00:24:03Z") -AnnotationAssertion( "CL:2000027") -AnnotationAssertion(rdfs:label "cerebellum basket cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cerebellum glutamatergic neuron) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any glutamatergic neuron that is part of a cerebellum.") -AnnotationAssertion( ) -AnnotationAssertion( "2014-06-25T00:24:10Z") -AnnotationAssertion( "CL:2000028") -AnnotationAssertion(rdfs:label "cerebellum glutamatergic neuron") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (central nervous system neuron) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any neuron that is part of a central nervous system.") -AnnotationAssertion( ) -AnnotationAssertion( "2014-06-25T01:17:43Z") -AnnotationAssertion( "CL:2000029") -AnnotationAssertion(rdfs:label "central nervous system neuron") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (hypothalamus cell) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any native cell that is part of a hypothalamus.") -AnnotationAssertion( ) -AnnotationAssertion( "2014-06-25T01:17:50Z") -AnnotationAssertion( "CL:2000030") -AnnotationAssertion(rdfs:label "hypothalamus cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (lateral line ganglion neuron) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any neuron that is part of a lateral line ganglion.") -AnnotationAssertion( ) -AnnotationAssertion( "2014-06-25T01:17:57Z") -AnnotationAssertion( "CL:2000031") -AnnotationAssertion(rdfs:label "lateral line ganglion neuron") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (peripheral nervous system neuron) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "ISBN:0721662544") "A neuron that is part of a peripheral nervous system.") -AnnotationAssertion( ) -AnnotationAssertion( "2014-06-25T02:28:17Z") -AnnotationAssertion( "FMA:84664") -AnnotationAssertion( "PNS neuron") -AnnotationAssertion( "peripheral neuron") -AnnotationAssertion( "CL:2000032") -AnnotationAssertion(rdfs:label "peripheral nervous system neuron") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (limb basal cell of epidermis) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any basal cell of epidermis that is part of a limb.") -AnnotationAssertion( ) -AnnotationAssertion( "2014-06-25T02:28:25Z") -AnnotationAssertion( "CL:2000033") -AnnotationAssertion(rdfs:label "limb basal cell of epidermis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (anterior lateral line neuromast hair cell) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any neuromast hair cell that is part of a anterior lateral line.") -AnnotationAssertion( ) -AnnotationAssertion( "2014-06-25T03:44:37Z") -AnnotationAssertion( "CL:2000034") -AnnotationAssertion(rdfs:label "anterior lateral line neuromast hair cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (posterior lateral line neuromast hair cell) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any neuromast hair cell that is part of a posterior lateral line.") -AnnotationAssertion( ) -AnnotationAssertion( "2014-06-25T03:44:57Z") -AnnotationAssertion( "CL:2000037") -AnnotationAssertion(rdfs:label "posterior lateral line neuromast hair cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (bladder microvascular endothelial cell) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any microvascular endothelial cell that is part of a urinary bladder.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "2014-07-09T00:04:47Z") -AnnotationAssertion( "CL:2000040") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "bladder microvascular endothelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (dermis microvascular lymphatic vessel endothelial cell) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any dermis lymphatic vessel endothelial cell that is part of a microvascular endothelium.") -AnnotationAssertion( ) -AnnotationAssertion( "2014-07-09T00:09:54Z") -AnnotationAssertion( "CL:2000041") -AnnotationAssertion(rdfs:label "dermis microvascular lymphatic vessel endothelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (embryonic fibroblast) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any fibroblast that is part of a embryo.") -AnnotationAssertion( ) -AnnotationAssertion( "2014-07-09T00:12:00Z") -AnnotationAssertion( "CL:2000042") -AnnotationAssertion(rdfs:label "embryonic fibroblast") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (brain pericyte) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any pericyte cell that is part of a brain.") -AnnotationAssertion( ) -AnnotationAssertion( "2014-07-09T00:18:22Z") -AnnotationAssertion( "CL:2000043") -AnnotationAssertion(rdfs:label "brain pericyte") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (brain microvascular endothelial cell) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any microvascular endothelial cell that is part of a brain.") -AnnotationAssertion( ) -AnnotationAssertion( "2014-07-09T00:24:53Z") -AnnotationAssertion( "CL:2000044") -AnnotationAssertion(rdfs:label "brain microvascular endothelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (foreskin melanocyte) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any melanocyte that is part of a prepuce of penis.") -AnnotationAssertion( ) -AnnotationAssertion( "2014-07-09T00:45:07Z") -AnnotationAssertion( "CL:2000045") -AnnotationAssertion(rdfs:label "foreskin melanocyte") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (ventricular cardiac muscle cell) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any cardiac muscle cell that is part of a cardiac ventricle.") -AnnotationAssertion( ) -AnnotationAssertion( "2014-08-12T20:50:28Z") -AnnotationAssertion( "CL:2000046") -AnnotationAssertion(rdfs:label "ventricular cardiac muscle cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (brainstem motor neuron) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any motor neuron that is part of a brainstem.") -AnnotationAssertion( ) -AnnotationAssertion( "2014-10-02T23:52:53Z") -AnnotationAssertion( "CL:2000047") -AnnotationAssertion(rdfs:label "brainstem motor neuron") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (primary motor cortex pyramidal cell) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any pyramidal cell that is part of a primary motor cortex.") -AnnotationAssertion( ) -AnnotationAssertion( "2014-10-06T17:39:04Z") -AnnotationAssertion( "CL:2000049") -AnnotationAssertion(rdfs:comment "http://www.ncbi.nlm.nih.gov/pubmed/12524689") -AnnotationAssertion(rdfs:label "primary motor cortex pyramidal cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (splenic fibroblast) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any fibroblast that is part of a spleen.") -AnnotationAssertion( ) -AnnotationAssertion( "2014-10-06T18:58:47Z") -AnnotationAssertion( "CL:2000051") -AnnotationAssertion(rdfs:label "splenic fibroblast") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (umbilical artery endothelial cell) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any endothelial cell of artery that is part of a umbilical cord.") -AnnotationAssertion( ) -AnnotationAssertion( "2014-10-06T19:01:48Z") -AnnotationAssertion( "CL:2000052") -AnnotationAssertion(rdfs:comment "http://www.sciencellonline.com/site/productInformation.php?keyword=8010") -AnnotationAssertion(rdfs:label "umbilical artery endothelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (splenic endothelial cell) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any endothelial cell that is part of a spleen.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "2014-10-06T19:06:04Z") -AnnotationAssertion( "CL:2000053") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "http://www.sciencellonline.com/site/productInformation.php?keyword=5500") -AnnotationAssertion(rdfs:label "splenic endothelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (liver dendritic cell) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any dendritic cell that is part of a liver.") -AnnotationAssertion( ) -AnnotationAssertion( "2014-10-06T19:16:11Z") -AnnotationAssertion( "hepatic dendritic cell") -AnnotationAssertion( "CL:2000055") -AnnotationAssertion(rdfs:comment "http://www.jleukbio.org/content/66/2/322.abstract") -AnnotationAssertion(rdfs:label "liver dendritic cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (femural osteoblast) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any osteoblast that is part of a femur.") -AnnotationAssertion( ) -AnnotationAssertion( "2014-10-06T19:29:45Z") -AnnotationAssertion( "CL:2000057") -AnnotationAssertion(rdfs:comment "http://www.sciencellonline.com/site/productInformation.php?keyword=4610") -AnnotationAssertion(rdfs:label "femural osteoblast") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (calvarial osteoblast) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any osteoblast that is part of a skull.") -AnnotationAssertion( ) -AnnotationAssertion( "2014-10-06T19:48:30Z") -AnnotationAssertion( "CL:2000058") -AnnotationAssertion(rdfs:comment "http://www.sciencellonline.com/site/productInformation.php?keyword=4600") -AnnotationAssertion(rdfs:label "calvarial osteoblast") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (prostate gland microvascular endothelial cell) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any microvascular endothelial cell that is part of a prostate gland.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "2014-10-07T17:46:27Z") -AnnotationAssertion( "CL:2000059") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "http://www.sciencellonline.com/site/productInformation.php?keyword=4400") -AnnotationAssertion(rdfs:label "prostate gland microvascular endothelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (placental villous trophoblast) - -AnnotationAssertion(Annotation( "PMID:31049600") "A trophoblast of placental villi. These cells fuse to form synctial trophoplast - the placental side of the interface between the placenta and maternal blood sinusoids in the decidua.") -AnnotationAssertion( ) -AnnotationAssertion( "2014-10-07T17:48:27Z") -AnnotationAssertion( "BTO:0006119") -AnnotationAssertion( "BTO:0006208") -AnnotationAssertion(Annotation( "PMID:31049600") "vCTB") -AnnotationAssertion( "villous cytotrophoblast") -AnnotationAssertion( "CL:2000060") -AnnotationAssertion(rdfs:comment "Same as synctial trophoblast?") -AnnotationAssertion(rdfs:label "placental villous trophoblast") -AnnotationAssertion(rdfs:seeAlso "http://www.sciencellonline.com/site/productInformation.php?keyword=7120") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (placental amniotic mesenchymal stromal cell) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any mesenchymal stem cell that is part of a placenta.") -AnnotationAssertion( ) -AnnotationAssertion( "2014-10-07T17:51:11Z") -AnnotationAssertion( "CL:2000061") -AnnotationAssertion(rdfs:comment "http://www.sciencellonline.com/site/productInformation.php?keyword=7140") -AnnotationAssertion(rdfs:label "placental amniotic mesenchymal stromal cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (placental villus capillary endothelial cell) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any capillary endothelial cell that is part of a placenta.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "2014-10-07T17:55:56Z") -AnnotationAssertion( "CL:2000062") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "http://www.ncbi.nlm.nih.gov/books/NBK53245/") -AnnotationAssertion(rdfs:label "placental villus capillary endothelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (ovarian fibroblast) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any fibroblast that is part of a female gonad.") -AnnotationAssertion( ) -AnnotationAssertion( "2014-10-07T17:57:42Z") -AnnotationAssertion( "CL:2000063") -AnnotationAssertion(rdfs:comment "http://www.sciencellonline.com/site/productInformation.php?keyword=7330") -AnnotationAssertion(rdfs:label "ovarian fibroblast") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (ovarian surface epithelial cell) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any epithelial cell that is part of a female gonad.") -AnnotationAssertion( ) -AnnotationAssertion( "2014-10-07T17:59:13Z") -AnnotationAssertion( "CL:2000064") -AnnotationAssertion(rdfs:comment "http://www.sciencellonline.com/site/productInformation.php?keyword=7310") -AnnotationAssertion(rdfs:label "ovarian surface epithelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (ovarian microvascular endothelial cell) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any microvascular endothelial cell that is part of a female urethra.") -AnnotationAssertion( ) -AnnotationAssertion( "2014-10-07T18:18:01Z") -AnnotationAssertion( "CL:2000065") -AnnotationAssertion(rdfs:comment "http://www.sciencellonline.com/site/productInformation.php?keyword=7300") -AnnotationAssertion(rdfs:label "ovarian microvascular endothelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cardiac ventricle fibroblast) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any fibroblast that is part of a cardiac ventricle.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "2014-10-07T18:35:38Z") -AnnotationAssertion( "CL:2000066") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "http://www.sciencellonline.com/site/productInformation.php?keyword=6310") -AnnotationAssertion(rdfs:label "cardiac ventricle fibroblast") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cardiac atrium fibroblast) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any fibroblast that is part of a cardiac atrium.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "2014-10-07T18:36:54Z") -AnnotationAssertion( "CL:2000067") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "http://www.sciencellonline.com/site/productInformation.php?keyword=6320") -AnnotationAssertion(rdfs:label "cardiac atrium fibroblast") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (pericardium fibroblast) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any fibroblast that is part of a pericardium.") -AnnotationAssertion( ) -AnnotationAssertion( "2014-10-07T18:38:06Z") -AnnotationAssertion( "CL:2000068") -AnnotationAssertion(rdfs:comment "http://www.sciencellonline.com/site/productInformation.php?keyword=6430") -AnnotationAssertion(rdfs:label "pericardium fibroblast") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (gallbladder fibroblast) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any fibroblast that is part of a gallbladder.") -AnnotationAssertion( ) -AnnotationAssertion( "2014-10-07T18:41:43Z") -AnnotationAssertion( "CL:2000069") -AnnotationAssertion(rdfs:comment "http://www.sciencellonline.com/site/productInformation.php?keyword=5430") -AnnotationAssertion(rdfs:label "gallbladder fibroblast") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (optic choroid fibroblast) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any fibroblast that is part of a optic choroid.") -AnnotationAssertion( ) -AnnotationAssertion( "2014-10-07T18:50:43Z") -AnnotationAssertion( "CL:2000070") -AnnotationAssertion(rdfs:comment "http://www.sciencellonline.com/site/productInformation.php?keyword=6620") -AnnotationAssertion(rdfs:label "optic choroid fibroblast") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (mammary microvascular endothelial cell) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any microvascular endothelial cell that is part of a breast.") -AnnotationAssertion( ) -AnnotationAssertion( "2014-10-07T19:55:30Z") -AnnotationAssertion( "CL:2000071") -AnnotationAssertion(rdfs:comment "http://www.sciencellonline.com/site/productInformation.php?keyword=7600") -AnnotationAssertion(rdfs:label "mammary microvascular endothelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (adipose microvascular endothelial cell) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any microvascular endothelial cell that is part of a adipose tissue.") -AnnotationAssertion( ) -AnnotationAssertion( "2014-10-07T22:13:45Z") -AnnotationAssertion( "CL:2000072") -AnnotationAssertion(rdfs:comment "http://www.sciencellonline.com/site/productInformation.php?keyword=7200") -AnnotationAssertion(rdfs:label "adipose microvascular endothelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (migratory cardiac neural crest cell) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any migratory neural crest cell that is part of a cardiac neural crest.") -AnnotationAssertion( ) -AnnotationAssertion( "2014-11-05T01:18:43Z") -AnnotationAssertion(Annotation( "PMID:33060096") "cardiac neural crest cell") -AnnotationAssertion( "CL:2000073") -AnnotationAssertion(rdfs:label "migratory cardiac neural crest cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (splenocyte) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any leukocyte that is part of a spleen.") -AnnotationAssertion( ) -AnnotationAssertion( "2014-11-05T01:26:50Z") -AnnotationAssertion( "CL:2000074") -AnnotationAssertion(rdfs:comment "Splenocytes is a vague term that refers to any one of the different white blood cell types in the spleen. This name is seen many references as such and is not explained further, necessitating a need for this terminology.") -AnnotationAssertion(rdfs:label "splenocyte") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (anterior visceral endoderm cell) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any endodermal cell that is part of a anterior visceral endoderm.") -AnnotationAssertion( ) -AnnotationAssertion( "2014-11-05T01:34:13Z") -AnnotationAssertion( "CL:2000075") -AnnotationAssertion(rdfs:label "anterior visceral endoderm cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (hindlimb stylopod vein endothelial cell) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any vein endothelial cell that is part of a hindlimb stylopod.") -AnnotationAssertion( ) -AnnotationAssertion( "2014-12-02T18:40:47Z") -AnnotationAssertion( "CL:2000076") -AnnotationAssertion(rdfs:label "hindlimb stylopod vein endothelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (skeletal muscle tissue of pectoralis major striated muscle cell) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any striated muscle cell that is part of a skeletal muscle tissue of pectoralis major.") -AnnotationAssertion( ) -AnnotationAssertion( "2014-12-02T18:48:17Z") -AnnotationAssertion( "CL:2000077") -AnnotationAssertion(rdfs:label "skeletal muscle tissue of pectoralis major striated muscle cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (placental pericyte) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any pericyte cell that is part of a placenta.") -AnnotationAssertion( ) -AnnotationAssertion( "2014-12-02T18:51:03Z") -AnnotationAssertion( "CL:2000078") -AnnotationAssertion(rdfs:label "placental pericyte") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (mesenchymal stem cell of femoral bone marrow) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any mesenchymal stem cell of the bone marrow that is part of a femur.") -AnnotationAssertion( ) -AnnotationAssertion( "2014-12-02T19:07:31Z") -AnnotationAssertion( "CL:2000079") -AnnotationAssertion(rdfs:label "mesenchymal stem cell of femoral bone marrow") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (mesenchymal stem cell of abdominal adipose tissue) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any mesenchymal stem cell of adipose tissue that is part of an abdomen.") -AnnotationAssertion( ) -AnnotationAssertion( "2014-12-02T19:10:34Z") -AnnotationAssertion( "mesenchymal stem cell of abdominal adipose") -AnnotationAssertion( "CL:2000080") -AnnotationAssertion(rdfs:label "mesenchymal stem cell of abdominal adipose tissue") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (melanocyte of skin of face) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any melanocyte of skin that is part of a skin of face.") -AnnotationAssertion( ) -AnnotationAssertion( "2014-12-02T19:10:40Z") -AnnotationAssertion( "CL:2000081") -AnnotationAssertion(rdfs:label "melanocyte of skin of face") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (melanocyte of foreskin) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any melanocyte of skin that is part of a skin of prepuce of penis.") -AnnotationAssertion( ) -AnnotationAssertion( "2014-12-02T19:10:45Z") -AnnotationAssertion( "CL:2000082") -AnnotationAssertion(rdfs:label "melanocyte of foreskin") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (hair follicle dermal papilla cell of scalp) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any hair follicle dermal papilla cell that is part of a scalp.") -AnnotationAssertion( ) -AnnotationAssertion( "2014-12-02T19:10:50Z") -AnnotationAssertion( "CL:2000083") -AnnotationAssertion(rdfs:label "hair follicle dermal papilla cell of scalp") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (conjunctiva goblet cell) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any goblet cell that is part of a conjunctiva.") -AnnotationAssertion( ) -AnnotationAssertion( "2014-12-02T19:28:38Z") -AnnotationAssertion( "CL:2000084") -AnnotationAssertion(rdfs:label "conjunctiva goblet cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (mononuclear cell of umbilical cord) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any mononuclear cell that is part of a umbilical cord.") -AnnotationAssertion( ) -AnnotationAssertion( "2014-12-02T20:14:16Z") -AnnotationAssertion( "CL:2000085") -AnnotationAssertion(rdfs:label "mononuclear cell of umbilical cord") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (neocortex basket cell) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any basket cell that is part of a neocortex.") -AnnotationAssertion( ) -AnnotationAssertion( "2014-12-24T00:37:19Z") -AnnotationAssertion( "CL:2000086") -AnnotationAssertion(rdfs:label "neocortex basket cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (dentate gyrus of hippocampal formation basket cell) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any basket cell that is part of a dentate gyrus of hippocampal formation.") -AnnotationAssertion( ) -AnnotationAssertion( "2014-12-24T00:37:24Z") -AnnotationAssertion( "CL:2000087") -AnnotationAssertion(rdfs:label "dentate gyrus of hippocampal formation basket cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (Ammon's horn basket cell) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any basket cell that is part of a Ammon's horn.") -AnnotationAssertion( ) -AnnotationAssertion( "2014-12-24T00:37:30Z") -AnnotationAssertion( "CL:2000088") -AnnotationAssertion(rdfs:label "Ammon's horn basket cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (dentate gyrus granule cell) AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "PMID:17765709") "A granule cell that has soma location in the dentate gyrus cell layer of the hippocampal formation and has an elliptical cell body and characteristic cone-shaped tree of spiny apical dendrites. The branches extend throughout the molecular layer and the distal tips of the dendritic tree end just at the hippocampal fissure or at the ventricular surface. The dentate gyrus granule cell is the principal cell type of the dentate gyrus.") @@ -43970,461 +19679,6 @@ AnnotationAssertion( "CL:2000089") AnnotationAssertion(Annotation( "PMID:17765709") rdfs:comment "As far as can be determined, all dentate granule cells appear to project to CA3 and the axon trajectory is partially correlated with the position of the parent cell body.") AnnotationAssertion(rdfs:label "dentate gyrus granule cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (dentate gyrus of hippocampal formation stellate cell) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any stellate cell that is part of a dentate gyrus of hippocampal formation.") -AnnotationAssertion( ) -AnnotationAssertion( "2015-02-23T05:48:40Z") -AnnotationAssertion( "CL:2000090") -AnnotationAssertion(rdfs:label "dentate gyrus of hippocampal formation stellate cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (endometrial microvascular endothelial cell) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any microvascular endothelial cell that is part of a endometrial blood vessel.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "2015-03-31T21:02:36Z") -AnnotationAssertion( "CL:2000091") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "endometrial microvascular endothelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (hair follicular keratinocyte) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any keratinocyte that is part of a hair follicle.") -AnnotationAssertion( ) -AnnotationAssertion( "2015-03-31T21:07:02Z") -AnnotationAssertion( "CL:2000092") -AnnotationAssertion(rdfs:label "hair follicular keratinocyte") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (bronchus fibroblast of lung) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any fibroblast of lung that is part of a bronchus.") -AnnotationAssertion( ) -AnnotationAssertion( "2015-03-31T21:16:22Z") -AnnotationAssertion( "CL:2000093") -AnnotationAssertion(rdfs:label "bronchus fibroblast of lung") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cord blood hematopoietic stem cell) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any hematopoietic stem cell that is part of a umbilical cord blood.") -AnnotationAssertion( ) -AnnotationAssertion( "2015-05-26T18:58:34Z") -AnnotationAssertion( "CL:2000095") -AnnotationAssertion(rdfs:label "cord blood hematopoietic stem cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (fibroblast of the reticular layer of dermis) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any fibroblast that is part of a reticular layer of dermis.") -AnnotationAssertion( ) -AnnotationAssertion( "2015-08-11T16:28:16Z") -AnnotationAssertion( "CL:2000096") -AnnotationAssertion(rdfs:label "fibroblast of the reticular layer of dermis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (midbrain dopaminergic neuron) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any dopaminergic neuron that is part of a midbrain.") -AnnotationAssertion( ) -AnnotationAssertion( "2015-12-03T16:42:40Z") -AnnotationAssertion( "CL:2000097") -AnnotationAssertion(rdfs:label "midbrain dopaminergic neuron") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (ciliated epithelial cell of esophagus) - -AnnotationAssertion(Annotation( "GOC:CellBLAST") Annotation( "PMID:29802404") "A ciliated epithelial cell of the esophagus.") -AnnotationAssertion( ) -AnnotationAssertion( "2019-02-09T16:40:30Z") -AnnotationAssertion( "CL:3000000") -AnnotationAssertion(rdfs:label "ciliated epithelial cell of esophagus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (sympathetic noradrenergic neuron) - -AnnotationAssertion(Annotation( "GOC:CellBLAST") Annotation( "PMID:30096314") "Sympathetic noradrenergic neuron.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "2019-02-25T19:30:14Z") -AnnotationAssertion( "CL:3000002") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "sympathetic noradrenergic neuron") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (sympathetic cholinergic neuron) - -AnnotationAssertion(Annotation( "GOC:CellBLAST") Annotation( "PMID:30096314") "Sympathetic cholinergic neuron.") -AnnotationAssertion( ) -AnnotationAssertion( "2019-02-25T19:32:20Z") -AnnotationAssertion( "CL:3000003") -AnnotationAssertion(rdfs:label "sympathetic cholinergic neuron") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (peripheral sensory neuron) - -AnnotationAssertion(Annotation( "GOC:CellBLAST") Annotation( "PMID:30096314") "Peripheral sensory neuron.") -AnnotationAssertion( ) -AnnotationAssertion( "2019-02-25T19:34:33Z") -AnnotationAssertion( "CL:3000004") -AnnotationAssertion(rdfs:label "peripheral sensory neuron") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (fibroblast of breast) - -AnnotationAssertion( "A fibroblast that is part of the breast.") -AnnotationAssertion( ) -AnnotationAssertion( "breast fibroblast") -AnnotationAssertion(rdfs:label "fibroblast of breast") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (fibroblast of skin of scalp) - -AnnotationAssertion( "A fibroblast that is part of the skin of scalp.") -AnnotationAssertion( ) -AnnotationAssertion( "skin of scalp fibroblast") -AnnotationAssertion(rdfs:label "fibroblast of skin of scalp") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (L6b glutamatergic cortical neuron) - -AnnotationAssertion( "L6b glut") -AnnotationAssertion(Annotation( "DOI:10.1101/2020.10.19.34312") Annotation( "PMID:30382198") "A glutamatergic neuron with a soma found in cortical layer 6b. They are transcriptomically related to corticothalamic-projecting neurons but have differential projections to the thalamus or anterior cingulate.") -AnnotationAssertion( ) -AnnotationAssertion( "ILX:0770163") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "L6b glutamatergic cortical neuron") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (amygdala excitatory neuron) - -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(Annotation( "DOI:10.1101/2022.10.12.511898") rdfs:comment "An excitatory neuron that is located in the amygdala.") -AnnotationAssertion(rdfs:label "amygdala excitatory neuron") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (cerebellar inhibitory GABAergic interneuron) - -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(Annotation( "DOI:10.1101/2022.10.12.511898") rdfs:comment "A GABAergic interneuron whose soma is located in the cerebellar cortex.") -AnnotationAssertion(rdfs:label "cerebellar inhibitory GABAergic interneuron") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (dentate gyrus neuron) - -AnnotationAssertion( "A neuron with its soma located in the dentate gyrus of the hippocampus.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "dentate gyrus neuron") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (medial ganglionic eminence derived interneuron) - -AnnotationAssertion( "MGE interneuron") -AnnotationAssertion(Annotation( "DOI:10.1101/2022.10.12.511898") "An interneuron that is derived from the medial ganglionic eminence.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "MGE interneuron") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "medial ganglionic eminence derived interneuron") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (caudal ganglionic eminence derived interneuron) - -AnnotationAssertion( "CGE interneuron") -AnnotationAssertion(Annotation( "DOI:10.1101/2022.10.12.511898") "An interneuron that is derived from the caudal ganglionic eminence.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "CGE interneuron") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "caudal ganglionic eminence derived interneuron") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (thalamic excitatory neuron) - -AnnotationAssertion(Annotation( "DOI:10.1101/2022.10.12.511898") "An excitatory neuron that has its soma located in the thalamic complex.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "thalamic excitatory neuron") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (medial ganglionic eminence derived GABAergic cortical interneuron) - -AnnotationAssertion( "MGE cortical gaba interneuron") -AnnotationAssertion(Annotation( "PMID:12637172") "A GABAergic cortical interneuron that develops from the medial ganglionic eminence and has migrated to the cerebral cortex.") -AnnotationAssertion( ) -AnnotationAssertion( "MGE cortical interneuron") -AnnotationAssertion(rdfs:label "medial ganglionic eminence derived GABAergic cortical interneuron") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (caudal ganglionic eminence derived GABAergic cortical interneuron) - -AnnotationAssertion( "CGE gaba cortical interneuron") -AnnotationAssertion(Annotation( "PMID:20130169") "A GABAergic cortical interneuron that develops from the caudal ganglionic eminence and has migrated to the cerebral cortex.") -AnnotationAssertion( ) -AnnotationAssertion( "CGE cortical interneuron") -AnnotationAssertion(rdfs:label "caudal ganglionic eminence derived GABAergic cortical interneuron") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (brain vascular cell) - -AnnotationAssertion(Annotation( "DOI:10.1101/2022.10.12.511898") "A cell that is part of the brain vasculature.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "brain vascular cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (mammillary body neuron) - -AnnotationAssertion(Annotation( "DOI:10.1101/2022.10.12.511898") "A neuron that has its soma located in the mammillary body.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "mammillary body neuron") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (midbrain-derived inhibitory neuron) - -AnnotationAssertion(Annotation( "DOI:10.1101/2022.10.12.511898") "A GABAergic inhibitory neuron that is derived from the midbrain.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "midbrain-derived inhibitory neuron") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (reticulospinal neuron) - -AnnotationAssertion(Annotation( "PMID:29720934") "A neuron with soma location in the reticular formation with axons that extend into the spinal cord such. Reticulospinal neuron activity can lead to a variety of motor behaviors.") -AnnotationAssertion( ) -AnnotationAssertion(Annotation( "PMID:29720934") "RSN") -AnnotationAssertion(rdfs:label "reticulospinal neuron") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (vasopressin-secreting magnocellular cell) - -AnnotationAssertion(Annotation( "WikipediaVersioned:Magnocellular_neurosecretory_cell&oldid=1021059931") "A magnocellular neurosecretory cell that is capable of producing and secreting vasopressin.") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "vasopressin-secreting magnocellular cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (amygdala pyramidal neuron) - -AnnotationAssertion(Annotation( "PMID:1375860") "A pyramidal neuron with soma located in the amygdala.") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "amygdala pyramidal neuron") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cerebral cortex pyramidal neuron) - -AnnotationAssertion(Annotation( "PMID:30715238") "A pyramidal neuron with soma located in the cerebral cortex.") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "cerebral cortex pyramidal neuron") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cochlea auditory hair cell) - -AnnotationAssertion(Annotation( "Wikipedia:Hair_cell") "An auditory hair cell found in the cochlea.") -AnnotationAssertion( ) -AnnotationAssertion( "FMA:62364") -AnnotationAssertion( "cochlear hair cell") -AnnotationAssertion(rdfs:label "cochlea auditory hair cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (myelinating glial cell) - -AnnotationAssertion(Annotation( "DOI:10.1007/3-540-29623-9_3240") "A glial cell that myelinates axonal processes.") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "myelinating glial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (somatosensory neuron) - -AnnotationAssertion(Annotation( "PMID:22865660") "A neuron that is part of the somatic sensory system. Somatosensory neurons innervate the skin or integument to detect different types of thermal, chemical, and mechanical touch stimuli.") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "somatosensory neuron") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (koniocellular cell) - -AnnotationAssertion(Annotation( "WikipediaVersioned:Lateral_geniculate_nucleus&oldid=1098375993") "A neuron with a small cell body that is located in a koniocellular layer of the lateral geniculate nucleus (LGN).") -AnnotationAssertion( ) -AnnotationAssertion( "NIFEXT:44") -AnnotationAssertion(Annotation( "PMID:10845061") "K cell") -AnnotationAssertion(Annotation( "PMID:10845061") rdfs:comment "In adult monkeys, koniocellular cells can be distinguished from parvocellular and magnocellular of the LGN by their expression of calbindin, the alpha subunit of type II calmodulin-dependent protein kinase, and the gamma subunit of protein kinase C.") -AnnotationAssertion(rdfs:label "koniocellular cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (pulmonary capillary endothelial cell) - -AnnotationAssertion( "Any capillary endothelial cell that is part of a lung.") -AnnotationAssertion( ) -AnnotationAssertion( "2021-11-23T02:31:40Z"^^xsd:dateTime) -AnnotationAssertion( "lung capillary endothelial cell") -AnnotationAssertion(rdfs:label "pulmonary capillary endothelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (choroidal melanocyte) - -AnnotationAssertion(Annotation( "PMID:31819095") Annotation( "http://orcid.org/0000-0002-0819-0473") "A melanocyte located in the vascular uvea and involved in photoprotection, regulation of oxidative damage and immune responses.") -AnnotationAssertion( ) -AnnotationAssertion( "2022-01-20T12:59:06Z"^^xsd:dateTime) -AnnotationAssertion( "uveal melanocyte") -AnnotationAssertion(Annotation( "PMID:31819095") Annotation( "PMID:34082079") rdfs:comment "Cellular functions and extracellular interactions of choroidal melanocytes are distinct to skin melanocytes. They might have both neuroectodermal as well as mesectodermal origins.") -AnnotationAssertion(rdfs:label "choroidal melanocyte") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (stromal cell of thymus) - -AnnotationAssertion(Annotation( "doi:10.1038/s41467-020-20082-7") "A stromal cell that is part of the thymus.") -AnnotationAssertion( ) -AnnotationAssertion( "2022-07-08T11:39:38Z"^^xsd:dateTime) -AnnotationAssertion( "thymic stromal cell") -AnnotationAssertion(rdfs:label "stromal cell of thymus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (pronephric podocyte) - -AnnotationAssertion(Annotation( ) Annotation( "PMID:10322630") "A specialized epithelial cell that contains \"feet\" that interdigitate with the \"feet\" of other glomerular epithelial cells in the pronephros.") -AnnotationAssertion( ) -AnnotationAssertion( "2022-03-11T14:38:32Z"^^xsd:dateTime) -AnnotationAssertion(Annotation( "ZFA:0001673") "pronephric glomerular visceral epithelial cell") -AnnotationAssertion(rdfs:label "pronephric podocyte") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (kidney loop of Henle short descending thin limb epithelial cell) - -AnnotationAssertion(Annotation( ) Annotation( "PMID:33769951") "Epithelial cell of the descending thin limb of the short loop (cortical) nephron limited to the outer medulla (mainly inner strip). It is known in some mammalian species that the short descending limb of the loop of Henle selectively expresses the serine protease Corin, the homeobox TF Uncx, and the urea channel Slc14a2.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "2022-05-13T11:00:29Z"^^xsd:dateTime) -AnnotationAssertion( "epithelial cell of the descending thin limb of the short loop of Henle") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "kidney loop of Henle short descending thin limb epithelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (epithelial cell of early distal convoluted tubule) - -AnnotationAssertion(Annotation( ) Annotation( "PMID:24855283") "An epithelial cell located in the early distal convoluted tubule.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "2022-06-21T12:47:48Z"^^xsd:dateTime) -AnnotationAssertion(Annotation( "PMID:24855283") "DCT1 cell") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "epithelial cell of early distal convoluted tubule") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (epithelial cell of late distal convoluted tubule) - -AnnotationAssertion(Annotation( ) Annotation( "PMID:24855283") "An epithelial cell located in the late distal convoluted tubule.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "2022-06-21T13:51:46Z"^^xsd:dateTime) -AnnotationAssertion(Annotation( "PMID:24855283") "DCT2 cell") -AnnotationAssertion( ) -AnnotationAssertion(Annotation( "PMID:24855283") rdfs:comment "Although mineralocorticoid receptors are expressed throughout the entire [distal convoluted tubule], the DCT2 is sensitive to the actions of aldosterone, because it expresses an enzyme called 11-β hydroxysteroid dehydrogenase 2 (11-βHSD2)") -AnnotationAssertion(rdfs:label "epithelial cell of late distal convoluted tubule") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (kidney connecting tubule principal cell) - -AnnotationAssertion(Annotation( ) Annotation( "PMID:27582101") Annotation( "PMID:31249312") "A renal principal cell located in the connecting tubule.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "2022-06-27T15:25:10Z"^^xsd:dateTime) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "kidney connecting tubule principal cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (renal medullary fibroblast) - -AnnotationAssertion(Annotation( ) Annotation( "PMID:10559635") "A fibroblast that is located in the renal medulla interstitium.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "2022-07-05T12:13:40Z"^^xsd:dateTime) -AnnotationAssertion( "kidney medullary fibroblast") -AnnotationAssertion( ) -AnnotationAssertion(Annotation( "PMID:10559635") rdfs:comment "It has been noted that inner medullary fibroblasts are involved in the regulation of water and electrolyte homeostasis.") -AnnotationAssertion(rdfs:label "renal medullary fibroblast") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (renal cortical fibroblast) - -AnnotationAssertion(Annotation( "PMID:10559635") "A fibroblast that is located in the renal cortical interstitium.") -AnnotationAssertion( ) -AnnotationAssertion( "2022-07-05T15:50:17Z"^^xsd:dateTime) -AnnotationAssertion( "kidney cortical fibroblast") -AnnotationAssertion(Annotation( "PMID:16230044") rdfs:comment "Renal cortical fibroblasts have key roles in mediating intercellular communication with neighboring/infiltrating cells and extracellular matrix and maintenance of renal tissue architecture. They additionally have an endocrine function in the production of epoetin.") -AnnotationAssertion(rdfs:label "renal cortical fibroblast") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (GABAergic amacrine cell) - -AnnotationAssertion(Annotation( "https://doi.org/10.1016/j.cell.2020.08.013") "An amacrine cell that uses GABA as a neurotransmitter.") -AnnotationAssertion( ) -AnnotationAssertion( "2022-10-17T12:35:11Z"^^xsd:dateTime) -AnnotationAssertion( "amacrine cell, GABAergic") -AnnotationAssertion(rdfs:label "GABAergic amacrine cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (blood lymphocyte) - -AnnotationAssertion(Annotation( ) "A lymphocyte located in blood.") -AnnotationAssertion( ) -AnnotationAssertion( "2022-11-04T14:40:00Z"^^xsd:dateTime) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "blood lymphocyte") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (interstitial cell) - -AnnotationAssertion(Annotation( "PMID:24987007") "Any cell that is located within the interstitium between the cells most prominent in defining a given tissue. \"Interstitial cell\" is a morphological term and refers to a variety of cells with differing origins and phenotypes.") -AnnotationAssertion( ) -AnnotationAssertion( "2022-11-30T14:35:08Z"^^xsd:dateTime) -AnnotationAssertion(rdfs:label "interstitial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (valve interstitial cell) - -AnnotationAssertion(Annotation( ) Annotation( "PMID:25311230") Annotation( "https://doi.org/10.1098/rsif.2017.0580") Annotation( "https://doi.org/10.1161/ATVBAHA.120.314789") Annotation( "https://doi.org/10.1161/JAHA.117.006339") Annotation( "https://doi.org/10.2353/ajpath.2007.070251") "An interstitial cell that is part of a cardiac valve leaflet. Along with valve endothelial cells, a valve interstitial cell maintains tissue homeostasis for the function of cardiac valves through secreting biochemical signals, matrix proteins and matrix remodeling enzymes.") -AnnotationAssertion( ) -AnnotationAssertion( "2022-12-06T14:18:45Z"^^xsd:dateTime) -AnnotationAssertion(Annotation( "PMID:25311230") Annotation( "PMID:30796046") Annotation( ) "VIC") -AnnotationAssertion( "cardiac valve interstitial cell") -AnnotationAssertion(Annotation( "PMID:25311230") "valvular interstitial cell") -AnnotationAssertion(Annotation( "PMID:25311230") rdfs:comment "Activated valve interstitial cells undergo continual turn over into deactivated fibroblasts and other cell fates (such as apoptosis).") -AnnotationAssertion(rdfs:label "valve interstitial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (valve endothelial cell) - -AnnotationAssertion(Annotation( "PMID:25311230") "An endothelial cell that lines a surface of a cardiac valve leaflet. Along with valve interstitial cells, a valve endothelial cell maintains tissue homeostasis for the function of cardiac valves through secreting biochemical signals, matrix proteins and matrix remodeling enzymes.") -AnnotationAssertion( ) -AnnotationAssertion( "2022-12-09T11:58:49Z"^^xsd:dateTime) -AnnotationAssertion(Annotation( "PMID:25311230") Annotation( "PMID:30796046") Annotation( ) "VEC") -AnnotationAssertion(Annotation( "PMID:25311230") "valvular endothelial cell") -AnnotationAssertion(Annotation( "PMID:25311230") rdfs:comment "At least in some mammalian species, a valve endothelial cell expresses CD31. Valve endothelial cells can undergo an endothelial to mesenchymal transition to acquire a fibroblast or myofibroblast phenotype that leads to changes in the microenvironmental signals and facilitates tissue regeneration.") -AnnotationAssertion(rdfs:label "valve endothelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (respiratory ciliated cell) @@ -44432,150 +19686,8 @@ AnnotationAssertion(Annotation( "2023-01-25T11:06:01Z"^^xsd:dateTime) AnnotationAssertion( "ciliated cell of the respiratory tract") AnnotationAssertion(rdfs:label "respiratory ciliated cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (dental pulp stem cell) - -AnnotationAssertion(Annotation( ) Annotation( "DOI:10.1177/154405910208100806") "A dental pulp cell that possesses stem-cell-like qualities, including self-renewal capability and multi-lineage differentiation.") -AnnotationAssertion( "2023-01-10T14:02:02Z"^^xsd:dateTime) -AnnotationAssertion(Annotation( ) "DPSC") -AnnotationAssertion(rdfs:label "dental pulp stem cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (endometrial ciliated epithelial cell) - -AnnotationAssertion(Annotation( "doi:10.1038/s41591-020-1040-z") Annotation( "https://www.proteinatlas.org/humanproteome/single+cell+type/Glandular+epithelial+cells#endometrialciliatedcells") "A ciliated cell of the endometrial epithelium. The cilia of this cell type help move mucus from glandular tissue of the endometrium.") -AnnotationAssertion( "2023-02-09T11:25:14Z"^^xsd:dateTime) -AnnotationAssertion( "ciliated cell of the uterus") -AnnotationAssertion( "uterine ciliated cell") -AnnotationAssertion( "ciliated cell of the endometrium") -AnnotationAssertion( "endometrium ciliated epithelial cell") -AnnotationAssertion(Annotation( "ttps://www.nature.com/articles/s41591-020-1040-z") rdfs:comment "In human samples, the expression of FOXJ1 protein, a regulator for motile cilia with epithelial lineage identity, has been noted.") -AnnotationAssertion(rdfs:label "endometrial ciliated epithelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (endothelial cell of venule of lymph node) - -AnnotationAssertion(Annotation( "PMID:28217126") "A(n) endothelial cell that is part of a(n) venule of lymph node.") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "endothelial cell of venule of lymph node") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (endothelial cell of arteriole of lymph node) - -AnnotationAssertion(Annotation( "PMID:28217126") "A(n) endothelial cell that is part of a(n) arteriole of lymph node.") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "endothelial cell of arteriole of lymph node") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (neuroendocrine cell of epithelium of crypt of Lieberkuhn) - -AnnotationAssertion(Annotation( "PMID:31390635") "A(n) neuroendocrine cell that is part of a(n) epithelium of crypt of Lieberkuhn.") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "neuroendocrine cell of epithelium of crypt of Lieberkuhn") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (myoepithelial cell of bronchus submucosal gland) - -AnnotationAssertion(Annotation( "PMID:19996346") Annotation( "PMID:5487122") "A(n) myoepithelial cell that is part of a(n) bronchus submucosal gland.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "myoepithelial cell of bronchus submucosal gland") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (smooth muscle cell of taenia coli) - -AnnotationAssertion(Annotation( "PMID:10715339") Annotation( "PMID:22320805") "A(n) smooth muscle cell that is part of a(n) taenia coli.") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "smooth muscle cell of taenia coli") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (serous secreting cell of bronchus submucosal gland) - -AnnotationAssertion(Annotation( "PMID:5487122") Annotation( "PMID:9651178") "A(n) serous secreting cell that is part of a(n) bronchus submucosal gland.") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "serous secreting cell of bronchus submucosal gland") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (endothelial cell of efferent lymphatic vessel) - -AnnotationAssertion(Annotation( "PMID:32094869") "A(n) endothelial cell that is part of a(n) efferent lymphatic vessel.") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "endothelial cell of efferent lymphatic vessel") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (brush cell of epithelium of lobar bronchus) - -AnnotationAssertion(Annotation( "PMID:15817800") "A(n) brush cell that is part of a(n) epithelium of lobar bronchus.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "brush cell of epithelium of lobar bronchus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (vein endothelial cell of respiratory system) - -AnnotationAssertion(Annotation( "PMID:34030460") "A(n) vein endothelial cell that is part of a(n) respiratory system.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "vein endothelial cell of respiratory system") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (goblet cell of epithelium of lobar bronchus) - -AnnotationAssertion(Annotation( "PMID:18757316") "A(n) goblet cell that is part of a(n) epithelium of lobar bronchus.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "goblet cell of epithelium of lobar bronchus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (neuroendocrine cell of epithelium of lobar bronchus) - -AnnotationAssertion(Annotation( "PMID:26711336") Annotation( "PMID:33355253") "A(n) neuroendocrine cell that is part of a(n) epithelium of lobar bronchus.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "neuroendocrine cell of epithelium of lobar bronchus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (smooth muscle cell of large intestine smooth muscle circular layer) - -AnnotationAssertion(Annotation( "PMID:24997029") "A(n) smooth muscle cell that is part of a(n) large intestine smooth muscle circular layer.") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "smooth muscle cell of large intestine smooth muscle circular layer") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (smooth muscle cell of large intestine smooth muscle longitudinal layer) - -AnnotationAssertion(Annotation( "PMID:24997029") "A(n) smooth muscle cell that is part of a(n) large intestine smooth muscle longitudinal layer.") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "smooth muscle cell of large intestine smooth muscle longitudinal layer") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (suprabasal keratinocyte) - -AnnotationAssertion(Annotation( "PMID:35883599") Annotation( "PMID:9520465") Annotation( "https://www.proteinatlas.org/humanproteome/single+cell+type/squamous+epithelial+cells#suprabasalkeratinocytes") "A keratinocyte of the epidermis suprabasal layer. This cell may express the differentiation markers keratin 10 and keratin 1.") -AnnotationAssertion( ) -AnnotationAssertion( "2023-02-02T11:17:04Z"^^xsd:dateTime) -AnnotationAssertion(rdfs:label "suprabasal keratinocyte") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (retinal astrocyte) - -AnnotationAssertion(Annotation( "PMID:25236977") Annotation( "PMID:33796062") "A star-shaped glial cell that is part of some retina. This cell links neurons to blood vessels and may provide structural and physiological support to optic nerve head axons.") -AnnotationAssertion( ) -AnnotationAssertion( "2023-03-02T14:38:32Z"^^xsd:dateTime) -AnnotationAssertion(Annotation( ) Annotation( "PMID:33796062") "retinal astroglia") -AnnotationAssertion( ) -AnnotationAssertion(Annotation( "PMID:32555229") Annotation( "PMID:33796062") rdfs:comment "In response to elevated intraocular pressure, a retinal astrocyte may modulate extracellular matrix remodeling. In the human retina, a retinal astrocyte is GFAP-positive, SOD3-positive and GYPC-positive.") -AnnotationAssertion(rdfs:label "retinal astrocyte") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (bronchiolar smooth muscle cell) AnnotationAssertion(Annotation( "ISBN:9781260462982") Annotation( "PMID:15347627") "A smooth muscle cell that is part of a bronchiole.") @@ -44585,99 +19697,8 @@ AnnotationAssertion( "2023-03-16T09:38:17Z"^^xsd:dateTime) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "bronchiolar smooth muscle cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (lung megakaryocyte) - -AnnotationAssertion(Annotation( "PMID:33351116") "A megakaryocyte that is resident in the lung connective tissue.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "2023-03-16T11:31:23Z"^^xsd:dateTime) -AnnotationAssertion(Annotation( "PMID:36524131") "lung resident megakaryocyte") -AnnotationAssertion(Annotation( "PMID:36524131") "lung-resident megakaryocyte") -AnnotationAssertion(Annotation( "PMID:36524131") Annotation( ) "MKL") -AnnotationAssertion(Annotation( "PMID:33351116") Annotation( ) Annotation( ) "lung MKs") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "lung megakaryocyte") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (mucus secreting cell of trachea gland) - -AnnotationAssertion(Annotation( "PMID:18931053") Annotation( "PMID:29656943") "A mucus secreting cell that is part of a submucosal gland of the trachea.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "2023-03-16T13:03:13Z"^^xsd:dateTime) -AnnotationAssertion(Annotation( "PMID:18931053") "tracheal submucosal gland mucous cell") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "mucus secreting cell of trachea gland") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (myoepithelial cell of trachea gland) - -AnnotationAssertion(Annotation( "PMID:29656943") "A myoepithelial cell that is part of a submucosal gland of the trachea.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "2023-03-16T13:36:43Z"^^xsd:dateTime) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "myoepithelial cell of trachea gland") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (mucus secreting cell of bronchus submucosal gland) - -AnnotationAssertion(Annotation( "PMID:19965983") "A mucus secreting cell of a submucosal gland of the bronchus.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "2023-03-16T15:12:52Z"^^xsd:dateTime) -AnnotationAssertion(Annotation( "PMID:5487122") "bronchial gland mucous cell") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "mucus secreting cell of bronchus submucosal gland") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (perichondrial fibroblast) - -AnnotationAssertion(Annotation( "wikipedia:Perichondrium") "A fibroblast that is part of the fibrous layer of the perichondrium. This cell is responsible for collagen fiber production.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "2023-03-16T16:12:50Z"^^xsd:dateTime) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "perichondrial fibroblast") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (lung perichondrial fibroblast) - -AnnotationAssertion(Annotation( "PMID:36543915") "A perichondrial fibroblast that is part of the lung.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "2023-03-16T16:15:39Z"^^xsd:dateTime) -AnnotationAssertion(Annotation( "PMID:36543915") Annotation( ) "PC-fibro") -AnnotationAssertion(rdfs:label "lung perichondrial fibroblast") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (mucus secreting cell of tracheobronchial tree submucosal gland) - -AnnotationAssertion(Annotation( "PMID:30864819") "A mucus secreting cell of a submucosal gland of the tracheobronchial tree.") -AnnotationAssertion( ) -AnnotationAssertion( "2023-04-20T10:55:50Z"^^xsd:dateTime) -AnnotationAssertion(rdfs:label "mucus secreting cell of tracheobronchial tree submucosal gland") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (taste receptor cell of tongue) - -AnnotationAssertion(Annotation( "DOI:10.1111/j.1096-3642.1981.tb01137.x") Annotation( "PMID:10052456") Annotation( "PMID:28655883") Annotation( "http://www.nejohnston.org/Birds/documents/AvianTongues_Johnston.pdf") "A taste receptor cell that is part of a taste bud of a tongue.") -AnnotationAssertion( ) -AnnotationAssertion( "2023-05-03T07:59:58Z"^^xsd:dateTime) -AnnotationAssertion(Annotation( "DOI:10.1016/s0022-5320(69)80043-2") "gustatory cell of tongue") -AnnotationAssertion(rdfs:label "taste receptor cell of tongue") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (catecholaminergic neuron) AnnotationAssertion(Annotation( "ISBN:0521442516") Annotation( "PMID:12094209") "A neuron that releases catecholamine as a neurotransmitter.") @@ -44685,7 +19706,6 @@ AnnotationAssertion( "2023-05-18T12:07:45Z"^^xsd:dateTime) AnnotationAssertion(Annotation( "PMID:10191060") Annotation( "PMID:12128258") Annotation( "PMID:34880760") Annotation( "https://orcid.org/0000-0002-2244-7917") rdfs:comment "Frequently used when describing the developing nervous system in zebrafish. A catecholaminergic neuron expresses tyrosine hydroxylase (TH), tyrosine hydroxylase 2 (TH2), aromatic amino acid decarboxylase (AADC), dopamine b-hydroxylase (DBH), and phenylethanolamine-N-methyl transferase (PEMT), which are enzymes necessary for catecholamine synthesis.") AnnotationAssertion(rdfs:label "catecholaminergic neuron") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (perivascular cell) @@ -44693,18 +19713,6 @@ AnnotationAssertion(Annotation( ) AnnotationAssertion( "2023-08-22T13:40:28Z"^^xsd:dateTime) AnnotationAssertion(rdfs:label "perivascular cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (enteroglial cell) - -AnnotationAssertion(Annotation( "PMID:16336493") Annotation( "PMID:17483847") Annotation( "PMID:25975510") "Glial cell that provides support to the enteric nervous system. It is involved in enteric neurotransmission, in maintaining the integrity of the mucosal barrier of the gut and serves as a link between the nervous and immune systems of the gut. In enteric nerve strands, glial processes ensheath multiaxonal bundles which distinguishes enteric glia from all other peripheral glia. Ultrastructurally, the most conspicuous trait of an enteroglial cell is the presence of 10 nm filaments, which criss-cross the cell body, form axial bundles in the processes and appear to firmly anchor the cells to the ganglionic surfaces. Similar to astrocytes, their main constituent is glial fibrillary acidic protein (GFAP).") -AnnotationAssertion( ) -AnnotationAssertion( "2023-04-03T15:15:40Z"^^xsd:dateTime) -AnnotationAssertion(Annotation( "PMID:11169131") Annotation( "PMID:25170211") "enteric glial cell") -AnnotationAssertion(Annotation( ) Annotation( "PMID:11169131") "enteric glia") -AnnotationAssertion(rdfs:label "enteroglial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) # Class: (fetal pre-type II pneumocyte) @@ -44736,108 +19744,6 @@ AnnotationAssertion(rdfs:label "repr SubClassOf( ) DisjointClasses( ) -# Class: (vacuole inheritance) - -AnnotationAssertion(Annotation( "GOC:mcc") Annotation( "PMID:10873824") Annotation( "PMID:14616069") "The distribution of vacuoles into daughter cells after mitosis or meiosis, mediated by interactions between vacuoles and the cytoskeleton.") -AnnotationAssertion( ) -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0000011") -AnnotationAssertion(rdfs:label "vacuole inheritance") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) -DisjointClasses( ObjectSomeValuesFrom( )) - -# Class: (regulation of DNA recombination) - -AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198506732") "Any process that modulates the frequency, rate or extent of DNA recombination, a DNA metabolic process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0000018") -AnnotationAssertion(rdfs:label "regulation of DNA recombination") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (acyl binding) - -AnnotationAssertion(Annotation( "GOC:curators") Annotation( "ISBN:0198506732") "Binding to an acyl group, any group formally derived by removal of the hydroxyl group from the acid function of a carboxylic acid.") -AnnotationAssertion( "acyl-CoA or acyl binding") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0000035") -AnnotationAssertion(rdfs:label "acyl binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (transition metal ion transport) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "The directed movement of transition metal ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver.") -AnnotationAssertion( "transition metal transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0000041") -AnnotationAssertion(rdfs:label "transition metal ion transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (mitotic sister chromatid segregation) - -AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:jl") "The cell cycle process in which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the mitotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner. One homolog of each morphologic type goes into each of the resulting chromosome sets.") -AnnotationAssertion( "GO:0016359") -AnnotationAssertion( "mitotic chromosome segregation") -AnnotationAssertion( "mitotic sister-chromatid adhesion release") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0000070") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "mitotic sister chromatid segregation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (Golgi membrane) - -AnnotationAssertion(Annotation( "GOC:mah") "The lipid bilayer surrounding any of the compartments of the Golgi apparatus.") -AnnotationAssertion( "Golgi apparatus membrane") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0000139") -AnnotationAssertion(rdfs:label "Golgi membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (nucleotide binding) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "ISBN:0198547684") "Binding to a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0000166") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "nucleotide binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (microtubule cytoskeleton organization) - -AnnotationAssertion(Annotation( "GOC:mah") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/23114"^^xsd:anyURI) -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/23195"^^xsd:anyURI) -AnnotationAssertion(Annotation( "GOC:mah") "microtubule cytoskeleton organisation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:mah") "microtubule cytoskeleton organization and biogenesis") -AnnotationAssertion( "GO:0000226") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "microtubule cytoskeleton organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (nuclear chromosome) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mah") "A chromosome that encodes the nuclear genome and is found in the nucleus of a eukaryotic cell during the cell cycle phases when the nucleus is intact.") -AnnotationAssertion( "nuclear interphase chromosome") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0000228") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "nuclear chromosome") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (polysaccharide biosynthetic process) AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways resulting in the formation of a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically.") @@ -44850,211 +19756,6 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0000271") AnnotationAssertion(rdfs:label "polysaccharide biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (polysaccharide catabolic process) - -AnnotationAssertion(Annotation( "PMID:33139480") "The chemical reactions and pathways resulting in the breakdown of a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically.") -AnnotationAssertion( "GO:0044244") -AnnotationAssertion( "polysaccharide breakdown") -AnnotationAssertion( "polysaccharide catabolism") -AnnotationAssertion( "polysaccharide degradation") -AnnotationAssertion( "multicellular organismal polysaccharide catabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0000272") -AnnotationAssertion(rdfs:label "polysaccharide catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (mitotic cell cycle) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "ISBN:0815316194") Annotation( "Reactome:69278") "Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent.") -AnnotationAssertion( "GO:0007067") -AnnotationAssertion( "Wikipedia:Mitosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "mitosis") -AnnotationAssertion( "GO:0000278") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "Note that this term should not be confused with 'GO:0140014 ; mitotic nuclear division'. 'GO:0000278 ; mitotic cell cycle represents the entire mitotic cell cycle, while 'GO:0140014 ; mitotic nuclear division' specifically represents the actual nuclear division step of the mitotic cell cycle.") -AnnotationAssertion(rdfs:label "mitotic cell cycle") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - -# Class: (nuclear division) - -AnnotationAssertion(Annotation( "GOC:mah") "The division of a cell nucleus into two nuclei, with DNA and other nuclear contents distributed between the daughter nuclei.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "karyokinesis") -AnnotationAssertion( "GO:0000280") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "nuclear division") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (adenine nucleotide transmembrane transporter activity) - -AnnotationAssertion(Annotation( "PMID:11566870") "Enables the transfer of adenine nucleotides (AMP, ADP, and ATP) from one side of a membrane to the other.") -AnnotationAssertion(Annotation(rdfs:label "PMP34-mediated exchange of cytosolic ATP for peroxisomal AMP") "Reactome:R-HSA-389652") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0000295") -AnnotationAssertion(rdfs:label "adenine nucleotide transmembrane transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (organellar ribosome) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:mcc") "A ribosome contained within a subcellular membrane-bounded organelle.") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0000313") -AnnotationAssertion(rdfs:label "organellar ribosome") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (lytic vacuole) - -AnnotationAssertion(Annotation( "GOC:krc") "A vacuole that is maintained at an acidic pH and which contains degradative enzymes, including a wide variety of acid hydrolases.") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0000323") -AnnotationAssertion(rdfs:label "lytic vacuole") -SubClassOf( ) - -# Class: (embryonic axis specification) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:go_curators") Annotation( "GOC:sdb_2009") Annotation( "GOC:tb") "The establishment, maintenance and elaboration of a pattern along a line or a point in an embryo.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "embryonic axis determination") -AnnotationAssertion( "GO:0000578") -AnnotationAssertion(rdfs:label "embryonic axis specification") -SubClassOf( ) -SubClassOf( ) - -# Class: (nuclear membrane fusion) - -AnnotationAssertion(Annotation( "GOC:elh") "The joining of 2 or more lipid bilayer membranes that surround the nucleus.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0000740") -AnnotationAssertion(rdfs:label "nuclear membrane fusion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (karyogamy) - -AnnotationAssertion(Annotation( "GOC:elh") "The creation of a single nucleus from multiple nuclei as a result of fusing the lipid bilayers that surround each nuclei.") -AnnotationAssertion( "GO:0007335") -AnnotationAssertion( "Wikipedia:Karyogamy") -AnnotationAssertion( "nuclear fusion") -AnnotationAssertion( "nuclear fusion during karyogamy") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0000741") -AnnotationAssertion(rdfs:label "karyogamy") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (syncytium formation by plasma membrane fusion) - -AnnotationAssertion(Annotation( "GOC:mtg_muscle") Annotation( "GOC:tb") "The formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells.") -AnnotationAssertion( "cell fusion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0000768") -AnnotationAssertion(rdfs:label "syncytium formation by plasma membrane fusion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (chromatin) - -AnnotationAssertion(Annotation( "GOC:elh") Annotation( "PMID:20404130") "The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome.") -AnnotationAssertion( "GO:0000789") -AnnotationAssertion( "GO:0000790") -AnnotationAssertion( "GO:0005717") -AnnotationAssertion( "NIF_Subcellular:sao1615953555") -AnnotationAssertion( "cytoplasmic chromatin") -AnnotationAssertion( "nuclear chromatin") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "chromosome scaffold") -AnnotationAssertion( "GO:0000785") -AnnotationAssertion(rdfs:comment "Chromosomes include parts that are not part of the chromatin. Examples include the kinetochore.") -AnnotationAssertion(rdfs:label "chromatin") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (euchromatin) - -AnnotationAssertion(Annotation( "PMID:32017156") "A dispersed and relatively uncompacted form of chromatin that is in a transcription-competent conformation.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/22355"^^xsd:anyURI) -AnnotationAssertion( "GO:0005719") -AnnotationAssertion( "GO:0035327") -AnnotationAssertion( "NIF_Subcellular:sao445485807") -AnnotationAssertion( "Wikipedia:Euchromatin") -AnnotationAssertion( "transcriptionally active chromatin") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "nuclear euchromatin") -AnnotationAssertion( "GO:0000791") -AnnotationAssertion(rdfs:label "euchromatin") -SubClassOf( ) - -# Class: (heterochromatin) - -AnnotationAssertion(Annotation( "PMID:32017156") "A compact and highly condensed form of chromatin that is refractory to transcription.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/22355"^^xsd:anyURI) -AnnotationAssertion( "GO:0005720") -AnnotationAssertion( "GO:0035328") -AnnotationAssertion( "NIF_Subcellular:sao581845896") -AnnotationAssertion( "Wikipedia:Heterochromatin") -AnnotationAssertion( "transcriptionally inactive chromatin") -AnnotationAssertion( "transcriptionally silent chromatin") -AnnotationAssertion( "nuclear heterochromatin") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0000792") -AnnotationAssertion(rdfs:label "heterochromatin") -SubClassOf( ) - -# Class: (sister chromatid segregation) - -AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:elh") "The cell cycle process in which sister chromatids are organized and then physically separated and apportioned to two or more sets.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0000819") -AnnotationAssertion(rdfs:label "sister chromatid segregation") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of glutamine family amino acid metabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline.") -AnnotationAssertion( "regulation of glutamine family amino acid metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0000820") -AnnotationAssertion(rdfs:label "regulation of glutamine family amino acid metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (cell morphogenesis) - -AnnotationAssertion(Annotation( "GOC:clt") Annotation( "GOC:dph") Annotation( "GOC:go_curators") Annotation( "GOC:tb") "The developmental process in which the size or shape of a cell is generated and organized.") -AnnotationAssertion( "GO:0007148") -AnnotationAssertion( "GO:0045790") -AnnotationAssertion( "GO:0045791") -AnnotationAssertion( "cellular morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0000902") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "cell morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (response to acid chemical) - -AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "GOC:rn") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by the chemical structure of the anion portion of a dissociated acid (rather than the acid acting as a proton donor). The acid chemical may be in gaseous, liquid or solid form.") -AnnotationAssertion( "response to acid") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "response to acid anion") -AnnotationAssertion( "response to oxoanion") -AnnotationAssertion( "GO:0001101") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "This term should be used to describe a response to a specific acid as a chemical. E.g., if an organism were responding to glutamate, then the response would be glutamate-specific; the organism is actually responding to the chemical structure of the anion portion of the dissociated acid. Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. If annotating experiments where an acid is playing a role as a proton donor, please annotate to GO:0010447 'response to acidic pH' instead.") -AnnotationAssertion(rdfs:label "response to acid chemical") -SubClassOf( ) # Class: (skeletal system development) @@ -45063,7 +19764,6 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0001501") AnnotationAssertion(rdfs:label "skeletal system development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) # Class: (ossification) @@ -45077,32 +19777,8 @@ AnnotationAssertion( "GO:0001503") AnnotationAssertion(rdfs:comment "Note that this term does not have a 'developmental process' parent because ossification isn't necessarily developmental, can also occur as part of bone remodeling. Instead use 'ossification involved in bone maturation ; GO:0043931'.") AnnotationAssertion(rdfs:label "ossification") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (neurotransmitter uptake) - -AnnotationAssertion(Annotation( "ISBN:0123668387") "The directed movement of neurotransmitters into neurons or glial cells. This process leads to inactivation and recycling of neurotransmitters.") -AnnotationAssertion( "neurotransmitter recycling") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "neurotransmitter import") -AnnotationAssertion( "neurotransmitter import into glial cell") -AnnotationAssertion( "neurotransmitter import into neuron") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0001504") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "neurotransmitter uptake") -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of neurotransmitter levels) - -AnnotationAssertion(Annotation( "GOC:jl") "Any process that modulates levels of neurotransmitter.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0001505") -AnnotationAssertion(rdfs:label "regulation of neurotransmitter levels") -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - # Class: (action potential) AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:go_curators") Annotation( "GOC:tb") Annotation( "ISBN:978-0-07-139011-8") "A process in which membrane potential cycles through a depolarizing spike, triggered in response to depolarization above some threshold, followed by repolarization. This cycle is driven by the flow of ions through various voltage gated channels with different thresholds and ion specificities.") @@ -45116,86 +19792,6 @@ SubClassOf( ObjectComplementOf(Object SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) DisjointClasses( ObjectSomeValuesFrom( )) -# Class: (angiogenesis) - -AnnotationAssertion(Annotation( "ISBN:0878932453") "Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels.") -AnnotationAssertion( "Wikipedia:Angiogenesis") -AnnotationAssertion(Annotation( ) "blood vessel formation from pre-existing blood vessels") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0001525") -AnnotationAssertion(rdfs:label "angiogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cilium or flagellum-dependent cell motility) - -AnnotationAssertion(Annotation( "GOC:cilia") Annotation( "GOC:hjd") Annotation( "GOC:krc") "Cell motility due to movement of eukaryotic cilia or bacterial-type flagella or archaeal-type flagella.") -AnnotationAssertion( "ciliary/flagellar motility") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "ciliary or bacterial-type flagellar motility") -AnnotationAssertion( "GO:0001539") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "Note that we deem eukaryotic cilia and microtubule-based flagella to be equivalent, while the bacterial- and archaeal-type flagella have a different structure. The former are microtubule-based structures that lash back and forth and are present only in eukaryotes, while the latter achieve motility by rotation. Bacterial- and archaeal-type flagella are superficially similar but have a different molecular composition and fine structure. These three structures never co-exist in the same organism. Therefore, GO:0001539 'cilium or flagellum-dependent cell motility' is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term. Direct annotations to GO:0001539 'cilium or flagellum-dependent cell motility' may be amended during annotation QC.") -AnnotationAssertion(rdfs:label "cilium or flagellum-dependent cell motility") -SubClassOf( ) - -# Class: (ovarian follicle development) - -AnnotationAssertion(Annotation( "https://www.ncbi.nlm.nih.gov/books/NBK279054/") "The process whose specific outcome is the progression of the ovarian follicle over time, from its formation to the mature structure.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "follicular phase") -AnnotationAssertion( "GO:0001541") -AnnotationAssertion(rdfs:label "ovarian follicle development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (primary ovarian follicle growth) - -AnnotationAssertion(Annotation( "GOC:mtg_mpo") Annotation( "https://www.ncbi.nlm.nih.gov/books/NBK279054/") "Increase in size of primary follicles including oocyte growth and granulosa and/or theca cell proliferation until more than one layer of granulosa cells is present (preantral follicle).") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0001545") -AnnotationAssertion(rdfs:label "primary ovarian follicle growth") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (preantral ovarian follicle growth) - -AnnotationAssertion(Annotation( "https://www.ncbi.nlm.nih.gov/books/NBK279054/") "Increase in size of follicles surrounded by two or more layers of granulosa cells up to the onset of antrum formation.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0001546") -AnnotationAssertion(rdfs:label "preantral ovarian follicle growth") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (antral ovarian follicle growth) - -AnnotationAssertion(Annotation( "https://www.ncbi.nlm.nih.gov/books/NBK279054/") "Increase in size of antral follicles due to cell proliferation and/or growth of the antral cavity.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0001547") -AnnotationAssertion(rdfs:label "antral ovarian follicle growth") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (ovarian cumulus expansion) - -AnnotationAssertion(Annotation( "PMID:30010832") "Increase in size of the cumulus surrounding the oocyte including change in morphology due to proliferation and dispersion of cumulus cells.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "ovarian cumulus growth") -AnnotationAssertion( "GO:0001550") -AnnotationAssertion(rdfs:label "ovarian cumulus expansion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (luteinization) AnnotationAssertion(Annotation( "https://www.ncbi.nlm.nih.gov/books/NBK279054/") "The set of processes resulting in differentiation of theca and granulosa cells into luteal cells and in the formation of a corpus luteum after ovulation.") @@ -45208,232 +19804,6 @@ AnnotationAssertion(rdfs:label "lute SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (oocyte growth) - -AnnotationAssertion(Annotation( "https://www.ncbi.nlm.nih.gov/books/NBK279054/") "The developmental growth process in which an oocyte irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0001555") -AnnotationAssertion(rdfs:label "oocyte growth") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - -# Class: (oocyte maturation) - -AnnotationAssertion(Annotation( "GOC:devbiol") Annotation( "https://www.ncbi.nlm.nih.gov/books/NBK279054/") "A developmental process, independent of morphogenetic (shape) change, that is required for an oocyte to attain its fully functional state. Oocyte maturation commences after reinitiation of meiosis commonly starting with germinal vesicle breakdown, and continues up to the second meiotic arrest prior to fertilization.") -AnnotationAssertion( "Wikipedia:Oocyte_maturation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0001556") -AnnotationAssertion(rdfs:label "oocyte maturation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - -# Class: (regulation of cell growth) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate, extent or direction of cell growth.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0001558") -AnnotationAssertion(rdfs:label "regulation of cell growth") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (blood vessel development) - -AnnotationAssertion(Annotation( "GOC:hjd") Annotation( "UBERON:0001981") "The process whose specific outcome is the progression of a blood vessel over time, from its formation to the mature structure. The blood vessel is the vasculature carrying blood.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0001568") -AnnotationAssertion(rdfs:label "blood vessel development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (branching involved in blood vessel morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") "The process of coordinated growth and sprouting of blood vessels giving rise to the organized vascular system.") -AnnotationAssertion(Annotation( "GOC:dph") "patterning of blood vessels") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0001569") -AnnotationAssertion(rdfs:label "branching involved in blood vessel morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (vasculogenesis) - -AnnotationAssertion(Annotation( "PMID:8999798") "The differentiation of endothelial cells from progenitor cells during blood vessel development, and the de novo formation of blood vessels and tubes.") -AnnotationAssertion( "Wikipedia:Vasculogenesis") -AnnotationAssertion( "vascular morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0001570") -AnnotationAssertion(rdfs:label "vasculogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (microtubule bundle formation) - -AnnotationAssertion(Annotation( "GOC:dph") "A process that results in a parallel arrangement of microtubules.") -AnnotationAssertion( "microtubule bundling") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0001578") -AnnotationAssertion(rdfs:label "microtubule bundle formation") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (G protein-coupled adenosine receptor activity) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:mah") Annotation( "PMID:9755289") "Combining with adenosine and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.") -AnnotationAssertion( "GO:0001610") -AnnotationAssertion( "GO:0001611") -AnnotationAssertion( "GO:0001612") -AnnotationAssertion( "GO:0001613") -AnnotationAssertion( "GO:0008501") -AnnotationAssertion( "adenosine nucleotide receptor") -AnnotationAssertion( "G protein coupled adenosine receptor activity") -AnnotationAssertion( "G-protein coupled adenosine receptor activity") -AnnotationAssertion(Annotation( "PMID:9755289") "P1 receptor") -AnnotationAssertion( "adenosine receptor activity, G protein coupled") -AnnotationAssertion(Annotation( "GOC:bf") "adenosine receptor activity, G-protein coupled") -AnnotationAssertion( "A1 adenosine receptor activity, G protein coupled") -AnnotationAssertion( "A1 adenosine receptor activity, G-protein coupled") -AnnotationAssertion( "A2A adenosine receptor activity, G protein coupled") -AnnotationAssertion( "A2A adenosine receptor activity, G-protein coupled") -AnnotationAssertion( "A2B adenosine receptor activity, G protein coupled") -AnnotationAssertion( "A2B adenosine receptor activity, G-protein coupled") -AnnotationAssertion( "A3 adenosine receptor activity, G protein coupled") -AnnotationAssertion( "A3 adenosine receptor activity, G-protein coupled") -AnnotationAssertion( "G protein coupled A1 adenosine receptor activity") -AnnotationAssertion( "G protein coupled A2A adenosine receptor activity") -AnnotationAssertion( "G protein coupled A2B adenosine receptor activity") -AnnotationAssertion( "G protein coupled A3 adenosine receptor activity") -AnnotationAssertion( "G-protein-coupled A1 adenosine receptor activity") -AnnotationAssertion( "G-protein-coupled A2A adenosine receptor activity") -AnnotationAssertion( "G-protein-coupled A2B adenosine receptor activity") -AnnotationAssertion( "G-protein-coupled A3 adenosine receptor activity") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0001609") -AnnotationAssertion(rdfs:label "G protein-coupled adenosine receptor activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (purinergic nucleotide receptor activity) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:signaling") "Combining with a purine nucleotide and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2010-10-22T10:57:12Z") -AnnotationAssertion( "GO:0035586") -AnnotationAssertion(Annotation( "PMID:9755289") "purinoceptor") -AnnotationAssertion(Annotation( "PMID:9755289") "purinoreceptor") -AnnotationAssertion( "molecular_function") -AnnotationAssertion(Annotation( "PMID:9755289") "P2 receptor") -AnnotationAssertion( "purinergic receptor activity") -AnnotationAssertion( "GO:0001614") -AnnotationAssertion(rdfs:label "purinergic nucleotide receptor activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (G protein-coupled ADP receptor activity) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:signaling") Annotation( "PMID:11196645") "Combining with ADP and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.") -AnnotationAssertion( "GO:0045032") -AnnotationAssertion( "ADP receptor activity") -AnnotationAssertion( "ADP-activated nucleotide receptor activity") -AnnotationAssertion( "K101 receptor") -AnnotationAssertion(Annotation( "GOC:mah") "platelet ADP receptor activity") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "ADP-activated adenosine receptor activity") -AnnotationAssertion( "GO:0001621") -AnnotationAssertion(rdfs:label "G protein-coupled ADP receptor activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (osteoblast differentiation) - -AnnotationAssertion(Annotation( "CL:0000062") Annotation( "GOC:jid") Annotation( "GO_REF:0000034") "The process whereby a relatively unspecialized cell acquires the specialized features of an osteoblast, a mesodermal or neural crest cell that gives rise to bone.") -AnnotationAssertion( "osteoblast cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0001649") -AnnotationAssertion(rdfs:label "osteoblast differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (peptide receptor activity) - -AnnotationAssertion(Annotation( "GOC:jl") "Combining with an extracellular or intracellular peptide to initiate a change in cell activity.") -AnnotationAssertion( "endogenous peptide receptor activity") -AnnotationAssertion( "exogenous peptide receptor activity") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0001653") -AnnotationAssertion(rdfs:label "peptide receptor activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (eye development) - -AnnotationAssertion(Annotation( "GOC:jid") Annotation( "GOC:jl") "The process whose specific outcome is the progression of the eye over time, from its formation to the mature structure. The eye is the organ of sight.") -AnnotationAssertion( "GO:0042460") -AnnotationAssertion( "Wikipedia:Eye_development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0001654") -AnnotationAssertion(rdfs:label "eye development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (urogenital system development) - -AnnotationAssertion(Annotation( "GOC:go_curators") "The process whose specific outcome is the progression of the urogenital system over time, from its formation to the mature structure.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/22178"^^xsd:anyURI) -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0001655") -AnnotationAssertion(rdfs:label "urogenital system development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (metanephros development) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "ISBN:0192800752") "The process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. In mammals, the metanephros is the excretory organ of the fetus, which develops into the mature kidney and is formed from the rear portion of the nephrogenic cord. The metanephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0001656") -AnnotationAssertion(rdfs:label "metanephros development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (ureteric bud development) - -AnnotationAssertion(Annotation( "GOC:go_curators") "The process whose specific outcome is the progression of the ureteric bud over time, from its formation to the mature structure.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0001657") -AnnotationAssertion(rdfs:label "ureteric bud development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (branching involved in ureteric bud morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:16916378") "The process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules.") -AnnotationAssertion(Annotation( "GOC:dph") "ureteric bud branching") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0001658") -AnnotationAssertion(rdfs:label "branching involved in ureteric bud morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - # Class: (temperature homeostasis) AnnotationAssertion(Annotation( "GOC:jl") "A homeostatic process in which an organism modulates its internal body temperature.") @@ -45444,19 +19814,6 @@ AnnotationAssertion( "temperature homeostasis") SubClassOf( ) -# Class: (G protein-coupled receptor binding) - -AnnotationAssertion(Annotation( "GOC:ceb") Annotation( "GOC:dph") "Binding to a G protein-coupled receptor.") -AnnotationAssertion(Annotation(rdfs:label "Activation of GRIK3 homomer") "Reactome:R-HSA-500717") -AnnotationAssertion( "G protein coupled receptor binding") -AnnotationAssertion(Annotation( "GOC:bf") "G-protein coupled receptor binding") -AnnotationAssertion( "G protein coupled receptor ligand") -AnnotationAssertion( "G-protein-coupled receptor ligand") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0001664") -AnnotationAssertion(rdfs:label "G protein-coupled receptor binding") -SubClassOf( ) - # Class: (response to hypoxia) AnnotationAssertion(Annotation( "GOC:hjd") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.") @@ -45471,43 +19828,6 @@ AnnotationAssertion(rdfs:label "resp SubClassOf( ) SubClassOf( ) -# Class: (ameboidal-type cell migration) - -AnnotationAssertion(Annotation( "GOC:dph") "Cell migration that is accomplished by extension and retraction of a pseudopodium.") -AnnotationAssertion( "ameboid cell migration") -AnnotationAssertion( "amoeboid cell migration") -AnnotationAssertion( "amoeboidal cell migration") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0001667") -AnnotationAssertion(rdfs:comment "Note that this term refers to a mode of migration rather than to any particular cell type.") -AnnotationAssertion(rdfs:label "ameboidal-type cell migration") -SubClassOf( ) - -# Class: (acrosomal vesicle) - -AnnotationAssertion(Annotation( "ISBN:0124325653") Annotation( "ISBN:0198506732") "A structure in the head of a spermatozoon that contains acid hydrolases, and is concerned with the breakdown of the outer membrane of the ovum during fertilization. It lies just beneath the plasma membrane and is derived from the lysosome.") -AnnotationAssertion( "Wikipedia:Acrosome") -AnnotationAssertion(Annotation( "GOC:sart") "acrosomal granule") -AnnotationAssertion(Annotation( "GOC:dph") "acrosome") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0001669") -AnnotationAssertion(rdfs:label "acrosomal vesicle") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (male germ cell nucleus) - -AnnotationAssertion(Annotation( "CL:0000015") Annotation( "GOC:hjd") Annotation( "GOC:mtg_sensu") "The nucleus of a male germ cell, a reproductive cell in males.") -AnnotationAssertion( "GO:0043081") -AnnotationAssertion( "male germ-cell nucleus") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0001673") -AnnotationAssertion(rdfs:label "male germ cell nucleus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - # Class: (female germ cell nucleus) AnnotationAssertion(Annotation( "CL:0000021") Annotation( "GOC:hjd") "The nucleus of the female germ cell, a reproductive cell in females.") @@ -45516,24 +19836,10 @@ AnnotationAssertion( "cellular_component") AnnotationAssertion( "GO:0001674") AnnotationAssertion(rdfs:label "female germ cell nucleus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectAllValuesFrom( )) -# Class: (acrosome assembly) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:hjd") Annotation( "GOC:tb") "The formation of the acrosome from the spermatid Golgi.") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "acrosome formation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0001675") -AnnotationAssertion(rdfs:label "acrosome assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (formation of translation initiation ternary complex) AnnotationAssertion(Annotation( "GOC:hjd") "Formation of a complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2 (either eIF2 in eukaryotes, or IF2 in prokaryotes). In prokaryotes, fMet-tRNA (initiator) is used rather than Met-tRNA (initiator).") @@ -45541,20 +19847,9 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0001677") AnnotationAssertion(rdfs:label "formation of translation initiation ternary complex") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (intracellular glucose homeostasis) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:go_curators") Annotation( "GOC:tb") "A homeostatic process involved in the maintenance of a steady state level of glucose within a cell.") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "cell glucose homeostasis") -AnnotationAssertion( "cellular glucose homeostasis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0001678") -AnnotationAssertion(rdfs:label "intracellular glucose homeostasis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (histamine metabolic process) AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0395825172") "The chemical reactions and pathways involving histamine, a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans.") @@ -45562,38 +19857,10 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0001692") AnnotationAssertion(rdfs:label "histamine metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ) -# Class: (histamine biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0395825172") "The chemical reactions and pathways resulting in the formation of histamine, a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans.") -AnnotationAssertion( "GO:0001693") -AnnotationAssertion( "histamine anabolism") -AnnotationAssertion( "histamine biosynthesis") -AnnotationAssertion( "histamine formation") -AnnotationAssertion( "histamine synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0001694") -AnnotationAssertion(rdfs:label "histamine biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (histamine catabolic process) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0395825172") "The chemical reactions and pathways resulting in the breakdown of histamine, a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans.") -AnnotationAssertion( "histamine breakdown") -AnnotationAssertion( "histamine catabolism") -AnnotationAssertion( "histamine degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0001695") -AnnotationAssertion(rdfs:label "histamine catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - # Class: (gastric acid secretion) AnnotationAssertion(Annotation( "GOC:hjd") "The regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion.") @@ -45605,16 +19872,6 @@ SubClassOf( ) SubClassOf( ) -# Class: (embryonic development via the syncytial blastoderm) - -AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "GOC:mtg_sensu") "The process whose specific outcome is the progression of the embryo over time, from zygote formation through syncytial blastoderm to the hatching of the first instar larva. An example of this process is found in Drosophila melanogaster.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0001700") -AnnotationAssertion(rdfs:label "embryonic development via the syncytial blastoderm") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - # Class: (in utero embryonic development) AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "GOC:mtg_sensu") "The process whose specific outcome is the progression of the embryo in the uterus over time, from formation of the zygote in the oviduct, to birth. An example of this process is found in Mus musculus.") @@ -45625,37 +19882,12 @@ SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectAllValuesFrom( )) -# Class: (gastrulation with mouth forming second) - -AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "GOC:mtg_sensu") "A gastrulation process in which the initial invagination becomes the anus and the mouth forms second.") -AnnotationAssertion( "GO:0010003") -AnnotationAssertion( "GO:0048276") -AnnotationAssertion(Annotation( "GOC:dph") "deuterostomic gastrulation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0001702") -AnnotationAssertion(rdfs:label "gastrulation with mouth forming second") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - -# Class: (gastrulation with mouth forming first) - -AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "GOC:mtg_sensu") "A gastrulation process in which the initial invagination becomes the mouth and the anus forms second.") -AnnotationAssertion(Annotation( "GOC:dph") "protostomic gastrulation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0001703") -AnnotationAssertion(rdfs:label "gastrulation with mouth forming first") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - # Class: (formation of primary germ layer) AnnotationAssertion(Annotation( "GOC:go_curators") "The formation of the ectoderm, mesoderm and endoderm during gastrulation.") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0001704") AnnotationAssertion(rdfs:label "formation of primary germ layer") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) @@ -45666,7 +19898,6 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:0001705") AnnotationAssertion(rdfs:label "ectoderm formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) @@ -45677,7 +19908,6 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:0001706") AnnotationAssertion(rdfs:label "endoderm formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) @@ -45687,73 +19917,9 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:0001707") AnnotationAssertion(rdfs:label "mesoderm formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (morphogenesis of a polarized epithelium) - -AnnotationAssertion(Annotation( "GOC:dph") "The morphogenetic process in which the anatomical structures of a polarized epithelium are generated and organized. A polarized epithelium is an epithelium where the epithelial sheet is oriented with respect to the planar axis.") -AnnotationAssertion(Annotation( "GOC:dph") "epithelial polarization") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0001738") -AnnotationAssertion(rdfs:label "morphogenesis of a polarized epithelium") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (lens placode formation) - -AnnotationAssertion(Annotation( "GOC:dph") "The initial developmental process that will lead to the formation of an eye.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "optic placode formation") -AnnotationAssertion( "GO:0001743") -AnnotationAssertion(rdfs:label "lens placode formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (insect visual primordium formation) - -AnnotationAssertion(Annotation( "GOC:mtg_sensu") Annotation( "PMID:8402833") "Establishment of the optic lobe placode. In Drosophila, for example, the placode appears in the dorsolateral region of the head in late stage 11 embryos and is the precursor to the larval visual system.") -AnnotationAssertion( "GO:0007457") -AnnotationAssertion( "optic lobe and Bolwig's organ precursor formation") -AnnotationAssertion( "optic lobe placode formation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0001744") -AnnotationAssertion(rdfs:label "insect visual primordium formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (compound eye morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_sensu") "The morphogenetic process in which the anatomical structures of the compound eye are generated and organized. The adult compound eye is a precise assembly of 700-800 ommatidia. Each ommatidium is composed of 20 cells, identified by cell type and position. An example of compound eye morphogenesis is found in Drosophila melanogaster.") -AnnotationAssertion(Annotation( "PMID:11735386") "insect-type retina morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0001745") -AnnotationAssertion(rdfs:label "compound eye morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - -# Class: (insect visual primordium development) - -AnnotationAssertion(Annotation( "GOC:mtg_sensu") Annotation( "PMID:8402833") "The process whose specific outcome is the progression of the optic placode over time, from its formation to the mature structure. During embryonic stage 12 the placode starts to invaginate, forming a pouch. Cells that will form Bolwig's organ segregate from the ventral lip of this pouch, remaining in the head epidermis. The remainder of the invagination loses contact with the outer surface and becomes the optic lobe. An example of this process is found in Drosophila melanogaster.") -AnnotationAssertion( "GO:0048049") -AnnotationAssertion( "optic placode development") -AnnotationAssertion( "optic lobe and Bolwig's organ precursor development") -AnnotationAssertion( "optic lobe placode development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0001748") -AnnotationAssertion(rdfs:label "insect visual primordium development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - # Class: (photoreceptor outer segment) AnnotationAssertion(Annotation( "GOC:cilia") Annotation( "GOC:krc") Annotation( "GOC:pde") Annotation( "ISBN:0824072820") Annotation( "PMID:19501669") Annotation( "PMID:26574505") Annotation( "PMID:6771304") "The outer segment of a vertebrate photoreceptor that contains a stack of membrane discs embedded with photoreceptor proteins.") @@ -45766,52 +19932,6 @@ SubClassOf( ObjectSomeValuesFrom( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (compound eye photoreceptor cell differentiation) - -AnnotationAssertion(Annotation( "GOC:go_curators") "The process in which a relatively unspecialized cell acquires the specialized features of an eye photoreceptor cell.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0001751") -AnnotationAssertion(rdfs:label "compound eye photoreceptor cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (eye photoreceptor cell differentiation) - -AnnotationAssertion(Annotation( "GOC:go_curators") "The process in which a relatively unspecialized cell acquires the specialized features of a photoreceptor cell, as found in the eye, the primary visual organ of most organisms.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0001754") -AnnotationAssertion(rdfs:label "eye photoreceptor cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (neural crest cell migration) - -AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") Annotation( "ISBN:0878932437") "The characteristic movement of cells from the dorsal ridge of the neural tube to a variety of locations in a vertebrate embryo.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0001755") -AnnotationAssertion(rdfs:label "neural crest cell migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (somitogenesis) - -AnnotationAssertion(Annotation( "ISBN:0721662544") "The formation of mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo.") -AnnotationAssertion( "Wikipedia:Somitogenesis") -AnnotationAssertion(Annotation( ) "formation of mesodermal clusters") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0001756") -AnnotationAssertion(rdfs:label "somitogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (morphogenesis of a branching structure) AnnotationAssertion(Annotation( "ISBN:0721662544") "The process in which the anatomical structures of branches are generated and organized. A branch is a division or offshoot from a main stem. Examples in animals would include blood vessels, nerves, lymphatics and other endothelial or epithelial tubes.") @@ -45823,74 +19943,6 @@ SubClassOf( ) SubClassOf( ) -# Class: (neuron migration) - -AnnotationAssertion(Annotation( "CL:0000540") Annotation( "GOC:go_curators") "The characteristic movement of an immature neuron from germinal zones to specific positions where they will reside as they mature.") -AnnotationAssertion( "Wikipedia:Neural_development#Neuron_migration") -AnnotationAssertion( "Wikipedia:Neuron_migration") -AnnotationAssertion( "neuron chemotaxis") -AnnotationAssertion( "neuronal migration") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "neuron guidance") -AnnotationAssertion( "GO:0001764") -AnnotationAssertion(rdfs:label "neuron migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (establishment of lymphocyte polarity) - -AnnotationAssertion(Annotation( "GOC:mgi_curators") Annotation( "PMID:11244041") Annotation( "PMID:12615889") "The directed orientation of lymphocyte signaling molecules and associated membrane rafts towards a chemokine gradient or a contact point with an appropriate activating cell.") -AnnotationAssertion( "lymphocyte polarization") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0001767") -AnnotationAssertion(rdfs:label "establishment of lymphocyte polarity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (establishment of T cell polarity) - -AnnotationAssertion(Annotation( "GOC:mgi_curators") Annotation( "PMID:11244041") Annotation( "PMID:12615889") "The directed orientation of T cell signaling molecules and associated membrane rafts towards a chemokine gradient or a contact point with antigen presenting cell.") -AnnotationAssertion( "T cell polarization") -AnnotationAssertion( "T lymphocyte polarization") -AnnotationAssertion( "T-cell polarization") -AnnotationAssertion( "establishment of T lymphocyte polarity") -AnnotationAssertion( "establishment of T-cell polarity") -AnnotationAssertion( "establishment of T-lymphocyte polarity") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0001768") -AnnotationAssertion(rdfs:label "establishment of T cell polarity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (establishment of B cell polarity) - -AnnotationAssertion(Annotation( "GOC:mgi_curators") Annotation( "PMID:12615889") Annotation( "PMID:9692889") "The directed orientation of B cell signaling molecules and associated membrane rafts towards a chemokine gradient of a contact point with an antigen displaying cell.") -AnnotationAssertion( "B cell polarization") -AnnotationAssertion( "B lymphocyte polarization") -AnnotationAssertion( "B-cell polarization") -AnnotationAssertion( "establishment of B lymphocyte polarity") -AnnotationAssertion( "establishment of B-cell polarity") -AnnotationAssertion( "establishment of B-lymphocyte polarity") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0001769") -AnnotationAssertion(rdfs:comment "Note that 'antigen displaying cell' in this term encompasses cell types such as follicular dendritic cells which display the unprocessed antigens of a B cell, leading to activation of the B cells and antigen uptake and processing by the B cells.") -AnnotationAssertion(rdfs:label "establishment of B cell polarity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (myeloid dendritic cell activation) - -AnnotationAssertion(Annotation( "GOC:mgi_curators") Annotation( "ISBN:0781735149") "The change in morphology and behavior of a dendritic cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0001773") -AnnotationAssertion(rdfs:label "myeloid dendritic cell activation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - # Class: (cell activation) AnnotationAssertion(Annotation( "GOC:mgi_curators") "A multicellular organismal process by which exposure to an activating factor such as a cellular or soluble ligand results in a change in the morphology or behavior of a cell.") @@ -45904,186 +19956,6 @@ SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectAllValuesFrom( )) -# Class: (leukocyte homeostasis) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") "The process of regulating the proliferation and elimination of cells of the immune system such that the total number of cells of a particular cell type within a whole or part of an organism is stable over time in the absence of an outside stimulus.") -AnnotationAssertion( "immune cell homeostasis") -AnnotationAssertion( "leucocyte homeostasis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0001776") -AnnotationAssertion(rdfs:comment "Note that this term represents the return of immune system cell levels to stable numbers following an immune response as well as the proliferation and elimination of cells of the immune system required to maintain stable numbers in the absence of an outside stimulus.") -AnnotationAssertion(rdfs:label "leukocyte homeostasis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - -# Class: (T cell homeostatic proliferation) - -AnnotationAssertion(Annotation( "GOC:mgi_curators") Annotation( "ISBN:0781735149") "The non-specific expansion of T cell populations within a whole or part of an organism to reach to a total number of T cells which will then remain stable over time in the absence of an external stimulus.") -AnnotationAssertion( "T lymphocyte homeostatic proliferation") -AnnotationAssertion( "T-cell homeostatic proliferation") -AnnotationAssertion( "T-lymphocyte homeostatic proliferation") -AnnotationAssertion( "resting T cell proliferation") -AnnotationAssertion( "resting T-cell proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0001777") -AnnotationAssertion(rdfs:label "T cell homeostatic proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (neutrophil homeostasis) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:pr") Annotation( "PMID:12752675") Annotation( "PMID:12960266") "The process of regulating the proliferation and elimination of neutrophils such that the total number of neutrophils within a whole or part of an organism is stable over time in the absence of an outside stimulus.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0001780") -AnnotationAssertion(rdfs:comment "Note that this term represents the return of neutrophil levels to stable numbers following an immune response as well as the proliferation and elimination of neutrophils required to maintain stable numbers in the absence of an outside stimulus.") -AnnotationAssertion(rdfs:label "neutrophil homeostasis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (neutrophil apoptotic process) - -AnnotationAssertion(Annotation( "CL:0000775") Annotation( "GOC:add") Annotation( "GOC:mtg_apoptosis") Annotation( "PMID:12752675") Annotation( "PMID:12960266") "Any apoptotic process in a neutrophil, any of the immature or mature forms of a granular leukocyte that in its mature form has a nucleus with three to five lobes connected by slender threads of chromatin, and cytoplasm containing fine inconspicuous granules and stainable by neutral dyes.") -AnnotationAssertion( "apoptosis of neutrophils") -AnnotationAssertion( "neutrophil programmed cell death by apoptosis") -AnnotationAssertion( "programmed cell death of neutrophils by apoptosis") -AnnotationAssertion( "programmed cell death, neutrophils") -AnnotationAssertion( "neutrophil apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0001781") -AnnotationAssertion(rdfs:label "neutrophil apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (B cell homeostasis) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") Annotation( "PMID:12956429") "The process of regulating the proliferation and elimination of B cells such that the total number of B cells within a whole or part of an organism is stable over time in the absence of an outside stimulus.") -AnnotationAssertion( "B lymphocyte homeostasis") -AnnotationAssertion( "B-cell homeostasis") -AnnotationAssertion( "B-lymphocyte homeostasis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0001782") -AnnotationAssertion(rdfs:comment "Note that this term represents the return of B cell levels to stable numbers following an immune response as well as the proliferation and elimination of B cells required to maintain stable numbers in the absence of an outside stimulus.") -AnnotationAssertion(rdfs:label "B cell homeostasis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (B cell apoptotic process) - -AnnotationAssertion(Annotation( "CL:0000236") Annotation( "GOC:add") Annotation( "GOC:mtg_apoptosis") Annotation( "ISBN:0781735149") "Any apoptotic process in a B cell, a lymphocyte of B lineage with the phenotype CD19-positive and capable of B cell mediated immunity.") -AnnotationAssertion( "B cell programmed cell death by apoptosis") -AnnotationAssertion( "B lymphocyte apoptosis") -AnnotationAssertion( "B lymphocyte programmed cell death by apoptosis") -AnnotationAssertion( "B-cell apoptosis") -AnnotationAssertion( "B-cell programmed cell death by apoptosis") -AnnotationAssertion( "B-lymphocyte apoptosis") -AnnotationAssertion( "B-lymphocyte programmed cell death by apoptosis") -AnnotationAssertion( "apoptosis of B cells") -AnnotationAssertion( "apoptosis of B lymphocytes") -AnnotationAssertion( "apoptosis of B-cells") -AnnotationAssertion( "apoptosis of B-lymphocytes") -AnnotationAssertion( "programmed cell death of B cells by apoptosis") -AnnotationAssertion( "programmed cell death of B lymphocytes by apoptosis") -AnnotationAssertion( "programmed cell death of B-cells by apoptosis") -AnnotationAssertion( "programmed cell death of B-lymphocytes by apoptosis") -AnnotationAssertion( "programmed cell death, B cells") -AnnotationAssertion( "programmed cell death, B lymphocytes") -AnnotationAssertion( "programmed cell death, B-cells") -AnnotationAssertion( "programmed cell death, B-lymphocytes") -AnnotationAssertion( "B cell apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0001783") -AnnotationAssertion(rdfs:label "B cell apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (cytokine production) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") "The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/19116"^^xsd:anyURI) -AnnotationAssertion( "GO:0042032") -AnnotationAssertion( "GO:0042089") -AnnotationAssertion( "GO:0042107") -AnnotationAssertion( "GO:0050663") -AnnotationAssertion( "cytokine biosynthetic process") -AnnotationAssertion( "cytokine metabolic process") -AnnotationAssertion( "cytokine secretion") -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:mah") "interferon production") -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:mah") "interferon secretion") -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:mah") Annotation( "http://wiki.geneontology.org/index.php/Why_isn%27t_interleukin_in_GO%3F") "interleukin production") -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:mah") Annotation( "http://wiki.geneontology.org/index.php/Why_isn%27t_interleukin_in_GO%3F") "interleukin secretion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0001816") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.") -AnnotationAssertion(rdfs:label "cytokine production") -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of cytokine production) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") "Any process that modulates the frequency, rate, or extent of production of a cytokine.") -AnnotationAssertion( "GO:0042035") -AnnotationAssertion( "GO:0050707") -AnnotationAssertion( "regulation of cytokine anabolism") -AnnotationAssertion( "regulation of cytokine biosynthesis") -AnnotationAssertion( "regulation of cytokine formation") -AnnotationAssertion( "regulation of cytokine synthesis") -AnnotationAssertion( "regulation of cytokine biosynthetic process") -AnnotationAssertion( "regulation of cytokine secretion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0001817") -AnnotationAssertion(rdfs:label "regulation of cytokine production") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of cytokine production) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") "Any process that stops, prevents, or reduces the rate of production of a cytokine.") -AnnotationAssertion( "GO:0042036") -AnnotationAssertion( "GO:0050710") -AnnotationAssertion( "down regulation of cytokine biosynthetic process") -AnnotationAssertion( "down regulation of cytokine production") -AnnotationAssertion( "down-regulation of cytokine biosynthetic process") -AnnotationAssertion( "down-regulation of cytokine production") -AnnotationAssertion( "downregulation of cytokine biosynthetic process") -AnnotationAssertion( "downregulation of cytokine production") -AnnotationAssertion( "negative regulation of cytokine anabolism") -AnnotationAssertion( "negative regulation of cytokine biosynthesis") -AnnotationAssertion( "negative regulation of cytokine formation") -AnnotationAssertion( "negative regulation of cytokine synthesis") -AnnotationAssertion( "inhibition of cytokine biosynthetic process") -AnnotationAssertion( "inhibition of cytokine production") -AnnotationAssertion( "negative regulation of cytokine biosynthetic process") -AnnotationAssertion( "negative regulation of cytokine secretion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0001818") -AnnotationAssertion(rdfs:label "negative regulation of cytokine production") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of cytokine production) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") "Any process that activates or increases the frequency, rate or extent of production of a cytokine.") -AnnotationAssertion( "GO:0042108") -AnnotationAssertion( "GO:0050715") -AnnotationAssertion( "up regulation of cytokine production") -AnnotationAssertion( "up-regulation of cytokine production") -AnnotationAssertion( "upregulation of cytokine production") -AnnotationAssertion( "activation of cytokine production") -AnnotationAssertion( "positive regulation of cytokine biosynthetic process") -AnnotationAssertion( "positive regulation of cytokine secretion") -AnnotationAssertion( "stimulation of cytokine production") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0001819") -AnnotationAssertion(rdfs:label "positive regulation of cytokine production") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (serotonin secretion) AnnotationAssertion(Annotation( "GOC:ef") Annotation( "ISBN:0198506732") Annotation( "ISBN:0781735149") "The regulated release of serotonin by a cell. Serotonin (5-hydroxytryptamine, or 5-HT) is a monoamine synthesised in serotonergic neurons in the central nervous system, enterochromaffin cells in the gastrointestinal tract and some immune system cells.") @@ -46093,151 +19965,10 @@ AnnotationAssertion( "GOC:tb") "serotonin release") AnnotationAssertion( "GO:0001820") AnnotationAssertion(rdfs:label "serotonin secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ) -# Class: (histamine secretion) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "ISBN:0198506732") Annotation( "ISBN:0781735149") "The regulated release of histamine by a cell or tissue. It is formed by decarboxylation of histidine and it acts through receptors in smooth muscle and in secretory systems.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0001821") -AnnotationAssertion(rdfs:label "histamine secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (kidney development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_kidney_jan10") Annotation( "ISBN:0124020607") Annotation( "ISBN:0721662544") "The process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and/or excretes the end products of body metabolism in the form of urine.") -AnnotationAssertion( "Wikipedia:Kidney_development") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:rph") "nephrogenesis") -AnnotationAssertion( "GO:0001822") -AnnotationAssertion(rdfs:label "kidney development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (mesonephros development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "ISBN:0124020607") Annotation( "ISBN:0721662544") Annotation( "PMID:10535314") "The process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. In mammals, the mesonephros is the second of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the mesonephros will form the mature kidney.") -AnnotationAssertion(Annotation( "GOC:dph") "Wolffian body development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0001823") -AnnotationAssertion(rdfs:label "mesonephros development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (blastocyst development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "ISBN:0124020607") Annotation( "ISBN:0198542771") "The process whose specific outcome is the progression of the blastocyst over time, from its formation to the mature structure. The mammalian blastocyst is a hollow ball of cells containing two cell types, the inner cell mass and the trophectoderm.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0001824") -AnnotationAssertion(rdfs:comment "See also the Anatomical Dictionary for Mouse Development ontology terms 'TS5, embryo ; EMAP:23', 'TS5, inner cell mass ; EMAP:24' and 'TS5, trophectoderm; EMAP:28'.") -AnnotationAssertion(rdfs:label "blastocyst development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - -# Class: (blastocyst formation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "ISBN:0124020607") Annotation( "ISBN:0198542771") "The initial formation of a blastocyst from a solid ball of cells known as a morula.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0001825") -AnnotationAssertion(rdfs:comment "See also the Anatomical Dictionary for Mouse Development ontology term 'TS3, compacted morula ; EMAP:9'.") -AnnotationAssertion(rdfs:label "blastocyst formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (inner cell mass cell differentiation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "ISBN:0124020607") Annotation( "ISBN:0198542771") "The process in which a relatively unspecialized cell acquires specialized features of an inner cell mass cell.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0001826") -AnnotationAssertion(rdfs:comment "See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, inner cell mass ; EMAP:14'.") -AnnotationAssertion(rdfs:label "inner cell mass cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (trophectodermal cell differentiation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "ISBN:0124020607") Annotation( "ISBN:0198542771") "The process in which a relatively unspecialized cell acquires the specialized features of a trophectoderm cell.") -AnnotationAssertion( "trophectoderm cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0001829") -AnnotationAssertion(rdfs:comment "See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, trophectoderm ; EMAP:19'.") -AnnotationAssertion(rdfs:label "trophectodermal cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (trophectodermal cellular morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "ISBN:0124020607") Annotation( "ISBN:0198542771") "The morphogenesis of trophectoderm cells.") -AnnotationAssertion( "trophectoderm cellular morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0001831") -AnnotationAssertion(rdfs:comment "See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, trophectoderm ; EMAP:19', 'TS5, trophectoderm ; EMAP:28' and 'TS6, trophectoderm ; EMAP:39'.") -AnnotationAssertion(rdfs:label "trophectodermal cellular morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (blastocyst growth) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "ISBN:0124020607") Annotation( "ISBN:0198542771") "An increase in size of a blastocyst due to expansion of the blastocoelic cavity cell shape changes and cell proliferation.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0001832") -AnnotationAssertion(rdfs:comment "See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, blastocoelic cavity ; EMAP:17', 'TS5, blastocoelic cavity ; EMAP:27' and 'TS6, blastocoelic cavity ; EMAP:36'.") -AnnotationAssertion(rdfs:label "blastocyst growth") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (inner cell mass cell proliferation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:isa_complete") Annotation( "ISBN:0124020607") Annotation( "ISBN:0198542771") "The proliferation of cells in the inner cell mass.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0001833") -AnnotationAssertion(rdfs:comment "See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, inner cell mass ; EMAP:14' and 'TS5, inner cell mass ; EMAP:24'.") -AnnotationAssertion(rdfs:label "inner cell mass cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (trophectodermal cell proliferation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "ISBN:0124020607") Annotation( "ISBN:0198542771") "The proliferation of cells in the trophectoderm.") -AnnotationAssertion( "trophectoderm cell proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0001834") -AnnotationAssertion(rdfs:comment "See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, trophectoderm ; EMAP:19', 'TS5, trophectoderm ; EMAP:28' and 'TS6, trophectoderm ; EMAP:39'.") -AnnotationAssertion(rdfs:label "trophectodermal cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (epithelial to mesenchymal transition) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:14701881") "A transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.") -AnnotationAssertion( "EMT") -AnnotationAssertion( "epithelial-mesenchymal transition") -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:rl") "mesenchymal cell differentiation from epithelial cell") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0001837") -AnnotationAssertion(rdfs:label "epithelial to mesenchymal transition") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (embryonic epithelial tube formation) AnnotationAssertion(Annotation( "GOC:dph") Annotation( "ISBN:0824072820") "The morphogenesis of an embryonic epithelium into a tube-shaped structure.") @@ -46247,26 +19978,6 @@ AnnotationAssertion(rdfs:label "embr SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (neural plate morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "ISBN:0878932437") "The process in which the anatomical structures of the neural plate are generated and organized. The neural plate is a specialized region of columnar epithelial cells in the dorsal ectoderm that will give rise to nervous system tissue.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0001839") -AnnotationAssertion(rdfs:label "neural plate morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (neural plate development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:ef") Annotation( "ISBN:0878932437") Annotation( "ISBN:0878932585") "The process whose specific outcome is the progression of the neural plate over time, from its formation to the mature structure. The neural plate is a flat, thickened layer of ectodermal cells. The underlying dorsal mesoderm signals the ectodermal cells above it to elongate into columnar neural plate cells. The neural plate subsequently develops into the neural tube, which gives rise to the central nervous system.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0001840") -AnnotationAssertion(rdfs:label "neural plate development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (neural tube formation) AnnotationAssertion(Annotation( "GOC:dph") Annotation( "ISBN:0878932437") "The formation of a tube from the flat layer of ectodermal cells known as the neural plate. This will give rise to the central nervous system.") @@ -46277,152 +19988,18 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0001841") AnnotationAssertion(rdfs:label "neural tube formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (neural fold formation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "ISBN:0878932437") "The process in which the neural fold is formed. The edges of the neural plate thicken and move up to form a U-shaped structure called the neural groove.") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") "neural groove formation") -AnnotationAssertion( "GO:0001842") -AnnotationAssertion(rdfs:label "neural fold formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (neural tube closure) AnnotationAssertion(Annotation( "GOC:dph") Annotation( "ISBN:0878932437") "The last step in the formation of the neural tube, where the paired neural folds are brought together and fuse at the dorsal midline.") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0001843") AnnotationAssertion(rdfs:label "neural tube closure") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (polysaccharide immune receptor activity) - -AnnotationAssertion(Annotation( "PMID:14707091") "Combining with a polysaccharide and transmitting the signal to initiate an innate immune response. A polysaccharide is a polymer of many (typically more than 10) monosaccharide residues linked glycosidically.") -AnnotationAssertion( "polysaccharide receptor activity") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0001873") -AnnotationAssertion(rdfs:label "polysaccharide immune receptor activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (response to yeast) - -AnnotationAssertion(Annotation( "PMID:14707091") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a yeast species.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0001878") -AnnotationAssertion(rdfs:comment "defined as response to Saccharomycotina (true yeasts). This excludes fission yeast.") -AnnotationAssertion(rdfs:label "response to yeast") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (nucleoside binding) - -AnnotationAssertion(Annotation( "GOC:hjd") "Binding to a nucleoside, a compound consisting of a purine or pyrimidine nitrogenous base linked either to ribose or deoxyribose.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0001882") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "nucleoside binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (purine nucleoside binding) - -AnnotationAssertion(Annotation( "GOC:hjd") "Binding to a purine nucleoside, a compound consisting of a purine base linked either to ribose or deoxyribose.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0001883") -AnnotationAssertion(rdfs:label "purine nucleoside binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (endothelial cell development) - -AnnotationAssertion(Annotation( "GOC:dph") "The progression of an endothelial cell over time, from its formation to the mature structure.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0001885") -AnnotationAssertion(rdfs:label "endothelial cell development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (endothelial cell morphogenesis) - -AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "The change in form (cell shape and size) that occurs during the differentiation of an endothelial cell.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0001886") -AnnotationAssertion(rdfs:label "endothelial cell morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (liver development) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:068340007X") "The process whose specific outcome is the progression of the liver over time, from its formation to the mature structure. The liver is an exocrine gland which secretes bile and functions in metabolism of protein and carbohydrate and fat, synthesizes substances involved in the clotting of the blood, synthesizes vitamin A, detoxifies poisonous substances, stores glycogen, and breaks down worn-out erythrocytes.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0001889") -AnnotationAssertion(rdfs:label "liver development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (placenta development) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:068340007X") "The process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin.") -AnnotationAssertion( "placental development") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "placentation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0001890") -AnnotationAssertion(rdfs:label "placenta development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - -# Class: (embryonic placenta development) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:068340007X") "The embryonically driven process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin.") -AnnotationAssertion(Annotation( "GOC:dph") "fetal placenta development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0001892") -AnnotationAssertion(rdfs:label "embryonic placenta development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (maternal placenta development) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:068340007X") "Maternally driven process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin.") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") "decidua development") -AnnotationAssertion( "GO:0001893") -AnnotationAssertion(rdfs:label "maternal placenta development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (tissue homeostasis) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:isa_complete") "A homeostatic process involved in the maintenance of an internal steady state within a defined tissue of an organism, including control of cellular proliferation and death and control of metabolic function.") -AnnotationAssertion(Annotation( "GOC:add") "tissue maintenance") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0001894") -AnnotationAssertion(rdfs:label "tissue homeostasis") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (photoreceptor inner segment) AnnotationAssertion(Annotation( "GOC:add") Annotation( "PMID:12019563") "The inner segment of a vertebrate photoreceptor containing mitochondria, ribosomes and membranes where opsin molecules are assembled and passed to be part of the outer segment discs.") @@ -46434,185 +20011,6 @@ SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (regulation of protein phosphorylation) - -AnnotationAssertion(Annotation( "GOC:hjd") "Any process that modulates the frequency, rate or extent of addition of phosphate groups into an amino acid in a protein.") -AnnotationAssertion(Annotation( "GOC:bf") "regulation of protein amino acid phosphorylation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0001932") -AnnotationAssertion(rdfs:label "regulation of protein phosphorylation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of protein phosphorylation) - -AnnotationAssertion(Annotation( "GOC:hjd") "Any process that stops, prevents or reduces the rate of addition of phosphate groups to amino acids within a protein.") -AnnotationAssertion( "down regulation of protein amino acid phosphorylation") -AnnotationAssertion( "down-regulation of protein amino acid phosphorylation") -AnnotationAssertion( "downregulation of protein amino acid phosphorylation") -AnnotationAssertion(Annotation( "GOC:bf") "negative regulation of protein amino acid phosphorylation") -AnnotationAssertion( "inhibition of protein amino acid phosphorylation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0001933") -AnnotationAssertion(rdfs:label "negative regulation of protein phosphorylation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of protein phosphorylation) - -AnnotationAssertion(Annotation( "GOC:hjd") "Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to amino acids within a protein.") -AnnotationAssertion(Annotation( "GOC:bf") "positive regulation of protein amino acid phosphorylation") -AnnotationAssertion( "up regulation of protein amino acid phosphorylation") -AnnotationAssertion( "up-regulation of protein amino acid phosphorylation") -AnnotationAssertion( "upregulation of protein amino acid phosphorylation") -AnnotationAssertion( "activation of protein amino acid phosphorylation") -AnnotationAssertion( "stimulation of protein amino acid phosphorylation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0001934") -AnnotationAssertion(rdfs:label "positive regulation of protein phosphorylation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (endothelial cell proliferation) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") "The multiplication or reproduction of endothelial cells, resulting in the expansion of a cell population. Endothelial cells are thin flattened cells which line the inside surfaces of body cavities, blood vessels, and lymph vessels, making up the endothelium.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0001935") -AnnotationAssertion(rdfs:label "endothelial cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of endothelial cell proliferation) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that modulates the frequency, rate, or extent of endothelial cell proliferation.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0001936") -AnnotationAssertion(rdfs:label "regulation of endothelial cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of endothelial cell proliferation) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that stops, prevents, or reduces the rate or extent of endothelial cell proliferation.") -AnnotationAssertion( "down regulation of endothelial cell proliferation") -AnnotationAssertion( "down-regulation of endothelial cell proliferation") -AnnotationAssertion( "downregulation of endothelial cell proliferation") -AnnotationAssertion( "inhibition of endothelial cell proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0001937") -AnnotationAssertion(rdfs:label "negative regulation of endothelial cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of endothelial cell proliferation) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that activates or increases the rate or extent of endothelial cell proliferation.") -AnnotationAssertion( "up regulation of endothelial cell proliferation") -AnnotationAssertion( "up-regulation of endothelial cell proliferation") -AnnotationAssertion( "upregulation of endothelial cell proliferation") -AnnotationAssertion( "activation of endothelial cell proliferation") -AnnotationAssertion( "stimulation of endothelial cell proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0001938") -AnnotationAssertion(rdfs:label "positive regulation of endothelial cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (male pronucleus) - -AnnotationAssertion(Annotation( "GOC:hjd") Annotation( "ISBN:0198506732") "The pronucleus originating from the spermatozoa that was involved in fertilization.") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0001940") -AnnotationAssertion(rdfs:label "male pronucleus") -SubClassOf( ) - -# Class: (postsynaptic membrane organization) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:pr") "A process which results in the assembly, arrangement of constituent parts, or disassembly of a postsynaptic membrane, the specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft).") -AnnotationAssertion( "post-synaptic membrane organization") -AnnotationAssertion( "postsynaptic membrane organisation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0001941") -AnnotationAssertion(rdfs:label "postsynaptic membrane organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (hair follicle development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "UBERON:0002073") "The process whose specific outcome is the progression of the hair follicle over time, from its formation to the mature structure. A hair follicle is a tube-like opening in the epidermis where the hair shaft develops and into which the sebaceous glands open.") -AnnotationAssertion( "GO:0001943") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0001942") -AnnotationAssertion(rdfs:label "hair follicle development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (vasculature development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "UBERON:0002409") "The process whose specific outcome is the progression of the vasculature over time, from its formation to the mature structure. The vasculature is an interconnected tubular multi-tissue structure that contains fluid that is actively transported around the organism.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "vascular system development") -AnnotationAssertion( "GO:0001944") -AnnotationAssertion(rdfs:label "vasculature development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (lymph vessel development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "UBERON:0001473") "The process whose specific outcome is the progression of a lymph vessel over time, from its formation to the mature structure.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0001945") -AnnotationAssertion(rdfs:label "lymph vessel development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (lymphangiogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:11596157") "Lymph vessel formation when new vessels emerge from the proliferation of pre-existing vessels.") -AnnotationAssertion( "Wikipedia:Lymphangiogenesis") -AnnotationAssertion(Annotation( ) "lymph vessel formation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0001946") -AnnotationAssertion(rdfs:label "lymphangiogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (sebaceous gland cell differentiation) - -AnnotationAssertion(Annotation( "GOC:mgi_curators") Annotation( "PMID:15737203") "The process in which a relatively unspecialized epidermal cell acquires the specialized features of a sebaceous gland cell.") -AnnotationAssertion(Annotation( "GOC:mgi_curators") "sebocytes differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0001949") -AnnotationAssertion(rdfs:label "sebaceous gland cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (blood vessel maturation) - -AnnotationAssertion(Annotation( "GOC:dph") "A developmental process, independent of morphogenetic (shape) change, that is required for a blood vessel to attain its fully functional state.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0001955") -AnnotationAssertion(rdfs:label "blood vessel maturation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (positive regulation of neurotransmitter secretion) - -AnnotationAssertion(Annotation( "GOC:hjd") "Any process that activates or increases the frequency, rate or extent of the regulated release of a neurotransmitter.") -AnnotationAssertion( "up regulation of neurotransmitter secretion") -AnnotationAssertion( "up-regulation of neurotransmitter secretion") -AnnotationAssertion( "upregulation of neurotransmitter secretion") -AnnotationAssertion( "activation of neurotransmitter secretion") -AnnotationAssertion( "stimulation of neurotransmitter secretion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0001956") -AnnotationAssertion(rdfs:label "positive regulation of neurotransmitter secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - # Class: (intramembranous ossification) AnnotationAssertion(Annotation( "ISBN:0878932437") "Direct ossification that occurs within mesenchyme or an accumulation of relatively unspecialized cells.") @@ -46635,74 +20033,6 @@ AnnotationAssertion(rdfs:label "endo SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (regulation of cytokine-mediated signaling pathway) - -AnnotationAssertion(Annotation( "GOC:hjd") "Any process that modulates the frequency, rate or extent of the cytokine mediated signaling pathway.") -AnnotationAssertion( "regulation of cytokine and chemokine mediated signaling pathway") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "regulation of cytokine mediated signaling pathway") -AnnotationAssertion( "regulation of cytokine mediated signalling pathway") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0001959") -AnnotationAssertion(rdfs:label "regulation of cytokine-mediated signaling pathway") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (negative regulation of cytokine-mediated signaling pathway) - -AnnotationAssertion(Annotation( "GOC:hjd") "Any process that stops, prevents, or reduces the frequency, rate or extent of the cytokine mediated signaling pathway.") -AnnotationAssertion( "down regulation of cytokine mediated signaling pathway") -AnnotationAssertion( "down-regulation of cytokine mediated signaling pathway") -AnnotationAssertion( "downregulation of cytokine mediated signaling pathway") -AnnotationAssertion( "negative regulation of cytokine and chemokine mediated signaling pathway") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "negative regulation of cytokine mediated signaling pathway") -AnnotationAssertion( "negative regulation of cytokine mediated signalling pathway") -AnnotationAssertion( "inhibition of cytokine mediated signaling pathway") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0001960") -AnnotationAssertion(rdfs:label "negative regulation of cytokine-mediated signaling pathway") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of cytokine-mediated signaling pathway) - -AnnotationAssertion(Annotation( "GOC:hjd") "Any process that activates or increases the frequency, rate or extent of a cytokine mediated signaling pathway.") -AnnotationAssertion( "positive regulation of cytokine and chemokine mediated signaling pathway") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "positive regulation of cytokine mediated signaling pathway") -AnnotationAssertion( "positive regulation of cytokine mediated signalling pathway") -AnnotationAssertion( "up regulation of cytokine mediated signaling pathway") -AnnotationAssertion( "up-regulation of cytokine mediated signaling pathway") -AnnotationAssertion( "upregulation of cytokine mediated signaling pathway") -AnnotationAssertion( "activation of cytokine mediated signaling pathway") -AnnotationAssertion( "stimulation of cytokine mediated signaling pathway") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0001961") -AnnotationAssertion(rdfs:label "positive regulation of cytokine-mediated signaling pathway") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (synaptic transmission, dopaminergic) - -AnnotationAssertion(Annotation( "GOC:dos") Annotation( "GOC:dph") "The vesicular release of dopamine. from a presynapse, across a chemical synapse, the subsequent activation of dopamine receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.") -AnnotationAssertion( "dopaminergic synaptic transmission") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0001963") -AnnotationAssertion(rdfs:label "synaptic transmission, dopaminergic") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (G protein-coupled adenosine receptor signaling pathway) - -AnnotationAssertion(Annotation( "GOC:dph") "The series of molecular signals generated as a consequence of a receptor binding to extracellular adenosine and transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity.") -AnnotationAssertion(Annotation( "PMID:9755289") "P1 receptor signaling pathway") -AnnotationAssertion(Annotation( "PMID:9755289") "adenosine receptor signaling pathway, G-protein coupled") -AnnotationAssertion(Annotation( "GOC:mah") "adenosine receptor signalling pathway") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "adenosine receptor signaling pathway") -AnnotationAssertion( "GO:0001973") -AnnotationAssertion(rdfs:label "G protein-coupled adenosine receptor signaling pathway") -SubClassOf( ) - # Class: (nervous system process involved in regulation of systemic arterial blood pressure) AnnotationAssertion(Annotation( "GOC:mtg_cardio") Annotation( "ISBN:0721643949") "The regulation of blood pressure mediated by detection of stimuli and a neurological response.") @@ -46713,7 +20043,6 @@ AnnotationAssertion( "fast control of arterial pressure") AnnotationAssertion( "GO:0001976") AnnotationAssertion(rdfs:label "nervous system process involved in regulation of systemic arterial blood pressure") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (renal system process involved in regulation of blood volume) @@ -46762,19 +20091,6 @@ AnnotationAssertion(rdfs:label "regu SubClassOf( ) SubClassOf( ) -# Class: (regulation of systemic arterial blood pressure by circulatory renin-angiotensin) - -AnnotationAssertion(Annotation( "ISBN:0721643949") "The process in which angiotensinogen metabolites in the bloodstream modulate the force with which blood passes through the circulatory system. The process begins when renin is released and cleaves angiotensinogen.") -AnnotationAssertion( "circulatory renin-angiotensin blood pressure regulation") -AnnotationAssertion( "circulatory renin-angiotensin regulation of blood pressure") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "circulatory renin-angiotensin control of blood pressure") -AnnotationAssertion( "control of blood pressure by circulatory renin-angiotensin") -AnnotationAssertion( "renin-angiotensin blood pressure control") -AnnotationAssertion( "GO:0001991") -AnnotationAssertion(rdfs:label "regulation of systemic arterial blood pressure by circulatory renin-angiotensin") -SubClassOf( ) - # Class: (regulation of systemic arterial blood pressure by vasopressin) AnnotationAssertion(Annotation( "GOC:mtg_cardio") Annotation( "ISBN:0721643949") "The regulation of blood pressure mediated by the signaling molecule vasopressin. Vasopressin is produced in the hypothalamus, and affects vasoconstriction, and renal water transport.") @@ -46785,28 +20101,6 @@ AnnotationAssertion( "regulation of systemic arterial blood pressure by vasopressin") SubClassOf( ) -# Class: (renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure) - -AnnotationAssertion(Annotation( "GOC:dph") "The physiological response of the kidneys to a decrease in blood flow.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "renal response to blood flow during renin-angiotensin control of blood pressure") -AnnotationAssertion( "GO:0001999") -AnnotationAssertion(rdfs:label "renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (renin secretion into blood stream) - -AnnotationAssertion(Annotation( "ISBN:0721643949") "The regulated release of renin into the blood stream by juxtoglomerular cells.") -AnnotationAssertion( "renin release into blood stream") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002001") -AnnotationAssertion(rdfs:label "renin secretion into blood stream") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (detection of hypoxic conditions in blood by chemoreceptor signaling) AnnotationAssertion(Annotation( "GOC:dph") "The process in which information about a lack of oxygen are received and are converted to a molecular signal by chemoreceptors in the carotid bodies and the aortic bodies.") @@ -46826,19 +20120,9 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0002009") AnnotationAssertion(rdfs:label "morphogenesis of an epithelium") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (morphogenesis of an epithelial sheet) - -AnnotationAssertion(Annotation( "GOC:jl") "The process in which the anatomical structures of an epithelial sheet are generated and organized. An epithelial sheet is a flat surface consisting of closely packed epithelial cells.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002011") -AnnotationAssertion(rdfs:label "morphogenesis of an epithelial sheet") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - # Class: (regulation of blood volume by renin-angiotensin) AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_cardio") Annotation( "GOC:tb") Annotation( "ISBN:0721643949") "The process in which the renin-angiotensin system controls the rate of fluid intake and output into the blood.") @@ -46849,19 +20133,6 @@ AnnotationAssertion( "regulation of blood volume by renin-angiotensin") SubClassOf( ) -# Class: (renin-angiotensin regulation of aldosterone production) - -AnnotationAssertion(Annotation( "ISBN:0721643949") "The process in which an increase in active angiotensin stimulates the adrenal cortices to secrete aldosterone.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "renin-angiotensin control of aldosterone production") -AnnotationAssertion( "GO:0002018") -AnnotationAssertion(rdfs:label "renin-angiotensin regulation of aldosterone production") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (regulation of heart rate) AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") Annotation( "PMID:10358008") "Any process that modulates the frequency or rate of heart contraction.") @@ -46873,149 +20144,12 @@ AnnotationAssertion( "regulation of heart rate") SubClassOf( ) -# Class: (regulation of sodium ion transport) - -AnnotationAssertion(Annotation( "GOC:dph") "Any process that modulates the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion( "regulation of Na+ transport") -AnnotationAssertion( "regulation of sodium transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002028") -AnnotationAssertion(rdfs:label "regulation of sodium ion transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of L-glutamate import across plasma membrane) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that modulates the frequency, rate or extent of L-glutamate import into a cell.") -AnnotationAssertion( "al") -AnnotationAssertion( "2012-06-13T07:34:08Z") -AnnotationAssertion( "GO:1900920") -AnnotationAssertion( "regulation of L-glutamate import") -AnnotationAssertion( "regulation of L-glutamate transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of L-glutamate uptake") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002036") -AnnotationAssertion(rdfs:label "regulation of L-glutamate import across plasma membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of L-glutamate import across plasma membrane) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that stops, prevents or reduces the frequency, rate or extent of L-glutamate import into a cell.") -AnnotationAssertion( "al") -AnnotationAssertion( "2012-06-13T07:34:30Z") -AnnotationAssertion( "GO:1900921") -AnnotationAssertion( "down regulation of L-glutamate transport") -AnnotationAssertion( "down-regulation of L-glutamate transport") -AnnotationAssertion( "downregulation of L-glutamate transport") -AnnotationAssertion( "negative regulation of L-glutamate import") -AnnotationAssertion( "negative regulation of L-glutamate transport") -AnnotationAssertion( "regulation of L-glutamate import") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of L-glutamate import") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of L-glutamate import") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of L-glutamate import") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of L-glutamate import") -AnnotationAssertion( "inhibition of L-glutamate transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of L-glutamate uptake") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of L-glutamate uptake") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of L-glutamate uptake") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of L-glutamate uptake") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of L-glutamate uptake") -AnnotationAssertion( "GO:0002037") -AnnotationAssertion(rdfs:label "negative regulation of L-glutamate import across plasma membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of L-glutamate import across plasma membrane) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that activates or increases the frequency, rate or extent of L-glutamate import into a cell.") -AnnotationAssertion( "al") -AnnotationAssertion( "2012-06-13T07:34:38Z") -AnnotationAssertion( "GO:1900922") -AnnotationAssertion( "positive regulation of L-glutamate import") -AnnotationAssertion( "positive regulation of L-glutamate transport") -AnnotationAssertion( "up regulation of L-glutamate transport") -AnnotationAssertion( "upregulation of L-glutamate transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of L-glutamate import") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of L-glutamate import") -AnnotationAssertion( "up-regulation of L-glutamate transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of L-glutamate import") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of L-glutamate import") -AnnotationAssertion( "activation of L-glutamate transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of L-glutamate uptake") -AnnotationAssertion( "stimulation of L-glutamate transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of L-glutamate uptake") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of L-glutamate uptake") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of L-glutamate uptake") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of L-glutamate uptake") -AnnotationAssertion( "GO:0002038") -AnnotationAssertion(rdfs:label "positive regulation of L-glutamate import across plasma membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of neuroblast proliferation) - -AnnotationAssertion(Annotation( "GOC:dph") "Any process that activates or increases the rate of neuroblast proliferation.") -AnnotationAssertion( "up regulation of neuroblast proliferation") -AnnotationAssertion( "up-regulation of neuroblast proliferation") -AnnotationAssertion( "upregulation of neuroblast proliferation") -AnnotationAssertion( "activation of neuroblast proliferation") -AnnotationAssertion( "stimulation of neuroblast proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002052") -AnnotationAssertion(rdfs:label "positive regulation of neuroblast proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (positive regulation of mesenchymal cell proliferation) - -AnnotationAssertion(Annotation( "GOC:dph") "The process of activating or increasing the rate or extent of mesenchymal cell proliferation. Mesenchymal cells are loosely organized embryonic cells.") -AnnotationAssertion( "up regulation of mesenchymal cell proliferation") -AnnotationAssertion( "up-regulation of mesenchymal cell proliferation") -AnnotationAssertion( "upregulation of mesenchymal cell proliferation") -AnnotationAssertion( "activation of mesenchymal cell proliferation") -AnnotationAssertion( "stimulation of mesenchymal cell proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002053") -AnnotationAssertion(rdfs:label "positive regulation of mesenchymal cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (nucleobase binding) - -AnnotationAssertion(Annotation( "GOC:hjd") "Binding to a nucleobase, any of a class of pyrmidines or purines, organic nitrogenous bases.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0002054") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "nucleobase binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (adenine binding) - -AnnotationAssertion(Annotation( "GOC:hjd") "Binding to adenine, a purine base.") -AnnotationAssertion( "6-aminopurine binding") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0002055") -AnnotationAssertion(rdfs:label "adenine binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (purine nucleobase binding) - -AnnotationAssertion(Annotation( "GOC:hjd") "Binding to a purine nucleobase, an organic nitrogenous base with a purine skeleton.") -AnnotationAssertion(Annotation( "GOC:go_curators") "purine base binding") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "purine binding") -AnnotationAssertion( "GO:0002060") -AnnotationAssertion(rdfs:label "purine nucleobase binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (chondrocyte differentiation) AnnotationAssertion(Annotation( "GOC:dph") "The process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte. A chondrocyte is a polymorphic cell that forms cartilage.") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0002062") AnnotationAssertion(rdfs:label "chondrocyte differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) @@ -47025,201 +20159,9 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:0002063") AnnotationAssertion(rdfs:label "chondrocyte development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (epithelial cell development) - -AnnotationAssertion(Annotation( "GOC:dph") "The process whose specific outcome is the progression of an epithelial cell over time, from its formation to the mature structure. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002064") -AnnotationAssertion(rdfs:label "epithelial cell development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (columnar/cuboidal epithelial cell differentiation) - -AnnotationAssertion(Annotation( "GOC:dph") "The process in which a relatively unspecialized cell acquires specialized features of a columnar/cuboidal epithelial cell. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002065") -AnnotationAssertion(rdfs:label "columnar/cuboidal epithelial cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (columnar/cuboidal epithelial cell development) - -AnnotationAssertion(Annotation( "GOC:dph") "The process whose specific outcome is the progression of a columnar/cuboidal epithelial cell over time, from its formation to the mature structure. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002066") -AnnotationAssertion(rdfs:label "columnar/cuboidal epithelial cell development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (glandular epithelial cell differentiation) - -AnnotationAssertion(Annotation( "GOC:dph") "The process in which a relatively unspecialized cell acquires specialized features of a glandular epithelial cell. A glandular epithelial cell is a columnar/cuboidal epithelial cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002067") -AnnotationAssertion(rdfs:label "glandular epithelial cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (glandular epithelial cell development) - -AnnotationAssertion(Annotation( "GOC:dph") "The process whose specific outcome is the progression of a glandular epithelial cell over time, from its formation to the mature structure. A glandular epithelial cell is a columnar/cuboidal epithelial cell is a cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002068") -AnnotationAssertion(rdfs:label "glandular epithelial cell development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (columnar/cuboidal epithelial cell maturation) - -AnnotationAssertion(Annotation( "GOC:dph") "The developmental process, independent of morphogenetic (shape) change, that is required for a columna/cuboidal epithelial cell to attain its fully functional state. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002069") -AnnotationAssertion(rdfs:label "columnar/cuboidal epithelial cell maturation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (epithelial cell maturation) - -AnnotationAssertion(Annotation( "GOC:dph") "The developmental process, independent of morphogenetic (shape) change, that is required for an epithelial cell to attain its fully functional state. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002070") -AnnotationAssertion(rdfs:label "epithelial cell maturation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (glandular epithelial cell maturation) - -AnnotationAssertion(Annotation( "GOC:dph") "The developmental process, independent of morphogenetic (shape) change, that is required for a glandular epithelial cell to attain its fully functional state. A glandular epithelial cell is a columnar/cuboidal epithelial cell is a cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002071") -AnnotationAssertion(rdfs:label "glandular epithelial cell maturation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (optic cup morphogenesis involved in camera-type eye development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_sensu") Annotation( "GOC:sdb_2009") Annotation( "GOC:tb") Annotation( "ISBN:0878932437") "The invagination of the optic vesicle to form two-walled indentations, the optic cups, that will go on to form the retina. This process begins with the optic vesicle becoming a two-walled structure and its subsequent shape changes. It does not include the fate commitment of cells to become the pigmented retina and the neural retina. An example of this process is found in Mus musculus.") -AnnotationAssertion( "optic cup morphogenesis involved in camera-style eye development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002072") -AnnotationAssertion(rdfs:label "optic cup morphogenesis involved in camera-type eye development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (extraocular skeletal muscle development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_muscle") Annotation( "GOC:mtg_sensu") Annotation( "MA:0001271") Annotation( "PMID:16638982") "The process whose specific outcome is the progression of the extraocular skeletal muscle over time, from its formation to the mature structure. The extraocular muscle is derived from cranial mesoderm and controls eye movements. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle. An example of this process is found in Mus musculus.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002074") -AnnotationAssertion(rdfs:label "extraocular skeletal muscle development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (somitomeric trunk muscle development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:16638982") "The process whose specific outcome is the progression of the somitomeric trunk muscle over time, from its formation to the mature structure. The somitomeric trunk muscle is derived from somitomeric mesoderm. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle. An example of this process is found in Mus musculus.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002075") -AnnotationAssertion(rdfs:label "somitomeric trunk muscle development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (osteoblast development) - -AnnotationAssertion(Annotation( "GOC:dph") "The process whose specific outcome is the progression of an osteoblast over time, from its formation to the mature structure. Osteoblast development does not include the steps involved in committing a cranial neural crest cell or an osteoprogenitor cell to an osteoblast fate. An osteoblast is a cell that gives rise to bone.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002076") -AnnotationAssertion(rdfs:label "osteoblast development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (acrosomal membrane) - -AnnotationAssertion(Annotation( "GOC:dph") "The membrane that surrounds the acrosomal lumen. The acrosome is a special type of lysosome in the head of a spermatozoon that contains acid hydrolases and is concerned with the breakdown of the outer membrane of the ovum during fertilization.") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0002080") -AnnotationAssertion(rdfs:label "acrosomal membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (inhibition of neuroepithelial cell differentiation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:16678814") "Any process that prevents the activation of neuroepithelial cell differentiation. Neuroepithelial cell differentiation is the process in which epiblast cells acquire specialized features of neuroepithelial cells.") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "negative regulation of neural plate formation") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "repression of premature neural plate formation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002085") -AnnotationAssertion(rdfs:label "inhibition of neuroepithelial cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of respiratory gaseous exchange by nervous system process) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") Annotation( "PMID:12458206") "A process carried out by the nervous system that is required for the proper control of respiratory gaseous exchange. This process occurs in the respiratory center of the brain in vertebrates.") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "neurological control of breathing") -AnnotationAssertion( "regulation of respiratory gaseous exchange by neurological system process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002087") -AnnotationAssertion(rdfs:label "regulation of respiratory gaseous exchange by nervous system process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (lens development in camera-type eye) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "ISBN:0582064333") "The process whose specific outcome is the progression of the lens over time, from its formation to the mature structure. The lens is a transparent structure in the eye through which light is focused onto the retina. An example of this process is found in Mus musculus.") -AnnotationAssertion( "lens development") -AnnotationAssertion( "lens development in camera-style eye") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002088") -AnnotationAssertion(rdfs:label "lens development in camera-type eye") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (lens morphogenesis in camera-type eye) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_sensu") "The process in which the anatomical structures of the lens are generated and organized. The lens is a transparent structure in the eye through which light is focused onto the retina. An example of this process is found in Mus musculus.") -AnnotationAssertion( "lens morphogenesis") -AnnotationAssertion( "lens morphogenesis in camera-style eye") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002089") -AnnotationAssertion(rdfs:label "lens morphogenesis in camera-type eye") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (auditory receptor cell morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that alters the size or shape of an auditory receptor cell.") -AnnotationAssertion(Annotation( "GO:dph") "hair cell morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002093") -AnnotationAssertion(rdfs:label "auditory receptor cell morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (amphibian larval development) AnnotationAssertion(Annotation( "GOC:bf") Annotation( "PMID:27143402") "The process whose specific outcome is the progression of the amphibian larva over time, from its formation to the mature structure. Amphibian larvae, sometimes called pollywogs or tadpoles, hatch from eggs and begin to grow limbs and other adult physical features at various times, depending on the species, before they metamorphose into the adult form.") @@ -47234,22 +20176,10 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:0002119") AnnotationAssertion(rdfs:label "nematode larval development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectAllValuesFrom( )) -# Class: (osteoclast proliferation) - -AnnotationAssertion(Annotation( "CL:0000092") Annotation( "GOC:hjd") "The multiplication or reproduction of osteoclasts, resulting in the expansion of an osteoclast cell population. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue, which typically differentiates from monocytes.") -AnnotationAssertion( "hjd") -AnnotationAssertion( "2010-02-03T01:50:37Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002158") -AnnotationAssertion(rdfs:label "osteoclast proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - # Class: (larval development) AnnotationAssertion(Annotation( "GOC:jid") Annotation( "ISBN:0877795088") "The process whose specific outcome is the progression of the larva over time, from its formation to the mature structure. The larva is the early, immature form of an that at birth or hatching is fundamentally unlike its parent and must metamorphose before assuming the adult characters.") @@ -47279,192 +20209,6 @@ AnnotationAssertion(rdfs:label "inst SubClassOf( ) SubClassOf( ) -# Class: (male germ cell proliferation) - -AnnotationAssertion(Annotation( "GOC:hjd") "The multiplication or reproduction of male germ cells, resulting in the expansion of a cell population.") -AnnotationAssertion( "hjd") -AnnotationAssertion( "2010-11-18T02:35:14Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002176") -AnnotationAssertion(rdfs:label "male germ cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (cytoplasmic translation) - -AnnotationAssertion(Annotation( "GOC:hjd") "The chemical reactions and pathways resulting in the formation of a protein in the cytoplasm. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein.") -AnnotationAssertion( "hjd") -AnnotationAssertion( "2011-06-09T03:11:53Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002181") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "Note that this term applies to translation performed by cytoplasmic ribosomes, which is distinct from translation performed by organellar ribosomes. For mitochondrial translation, consider GO:0032543 'mitochondrial translation' or its child terms.") -AnnotationAssertion(rdfs:label "cytoplasmic translation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (cytoplasmic translational elongation) - -AnnotationAssertion(Annotation( "GOC:hjd") "The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis in the cytoplasm.") -AnnotationAssertion( "hjd") -AnnotationAssertion( "2011-06-09T03:14:42Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002182") -AnnotationAssertion(rdfs:label "cytoplasmic translational elongation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (cytoplasmic translational initiation) - -AnnotationAssertion(Annotation( "GOC:hjd") "The process preceding formation of the peptide bond between the first two amino acids of a protein in the cytoplasm. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA.") -AnnotationAssertion( "hjd") -AnnotationAssertion( "2011-06-09T03:15:48Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002183") -AnnotationAssertion(rdfs:label "cytoplasmic translational initiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (cytoplasmic translational termination) - -AnnotationAssertion(Annotation( "GOC:hjd") "The process resulting in the release of a polypeptide chain from the ribosome in the cytoplasm, usually in response to a termination codon.") -AnnotationAssertion( "hjd") -AnnotationAssertion( "2011-06-09T03:17:13Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002184") -AnnotationAssertion(rdfs:label "cytoplasmic translational termination") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (somatic diversification of immune receptors) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") Annotation( "PMID:16102575") Annotation( "PMID:16166509") "The somatic process allowing for the production of immune receptors whose specificity is not encoded in the germline genomic sequences.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002200") -AnnotationAssertion(rdfs:comment "Note that this process covers somatic recombination, gene conversion, hypermutation, N-region addition, and alternate splicing processes of immune receptor diversification.") -AnnotationAssertion(rdfs:label "somatic diversification of immune receptors") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (somatic recombination of immunoglobulin genes involved in immune response) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") "The process in which immunoglobulin genes are formed through recombination of the germline genetic elements, also known as immunoglobulin gene segments, within a single locus following the induction of and contributing to an immune response.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "somatic recombination of antibody genes during immune response") -AnnotationAssertion(Annotation( "GOC:dph") "somatic recombination of immunoglobulin genes during immune response") -AnnotationAssertion( "GO:0002204") -AnnotationAssertion(rdfs:label "somatic recombination of immunoglobulin genes involved in immune response") -SubClassOf( ) -SubClassOf( ) - -# Class: (somatic diversification of immunoglobulins involved in immune response) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") Annotation( "PMID:14991701") "The somatic process that results in the generation of sequence diversity of immunoglobulins after induction, and contributes to an immune response.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "somatic diversification of antibodies during immune response") -AnnotationAssertion(Annotation( "GOC:dph") "somatic diversification of immunoglobulins during immune response") -AnnotationAssertion( "GO:0002208") -AnnotationAssertion(rdfs:label "somatic diversification of immunoglobulins involved in immune response") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (defense response to insect) - -AnnotationAssertion(Annotation( "GOC:add") "A response to protect an organism from a directly detected or perceived external threat from an insect or insects to that organism.") -AnnotationAssertion( "GO:0002214") -AnnotationAssertion( "physiological defense response to insect") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002213") -AnnotationAssertion(rdfs:label "defense response to insect") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (defense response to nematode) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "PMID:11516579") Annotation( "PMID:14506883") "A response to protect an organism from a directly detected or perceived external threat from a nematode or nematodes, which results in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.") -AnnotationAssertion( "GO:0002216") -AnnotationAssertion( "physiological defense response to nematode") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002215") -AnnotationAssertion(rdfs:label "defense response to nematode") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of antimicrobial peptide production) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "PMID:11807545") "Any process that activates or increases the frequency, rate, or extent of antimicrobial peptide production.") -AnnotationAssertion( "antimicrobial peptide induction") -AnnotationAssertion( "up regulation of antimicrobial peptide production") -AnnotationAssertion( "up-regulation of antimicrobial peptide production") -AnnotationAssertion( "upregulation of antimicrobial peptide production") -AnnotationAssertion( "activation of antimicrobial peptide production") -AnnotationAssertion( "stimulation of antimicrobial peptide production") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002225") -AnnotationAssertion(rdfs:label "positive regulation of antimicrobial peptide production") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (leukocyte chemotaxis involved in inflammatory response) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") "The movement of an immune cell in response to an external stimulus contributing to an inflammatory response.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "immune cell chemotaxis during inflammatory response") -AnnotationAssertion( "leucocyte chemotaxis during inflammatory response") -AnnotationAssertion(Annotation( "GOC:dph") "leukocyte chemotaxis during inflammatory response") -AnnotationAssertion( "GO:0002232") -AnnotationAssertion(rdfs:label "leukocyte chemotaxis involved in inflammatory response") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (leukocyte chemotaxis involved in immune response) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") "The movement of an immune cell in response to an external stimulus a part of an immune response.") -AnnotationAssertion( "immune cell chemotaxis during immune response") -AnnotationAssertion( "leucocyte chemotaxis during immune response") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002233") -AnnotationAssertion(rdfs:label "leukocyte chemotaxis involved in immune response") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (hematopoietic progenitor cell differentiation) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:rl") Annotation( "ISBN:0781735149") Annotation( "PMID:16551251") "The process in which precursor cell type acquires the specialized features of a hematopoietic progenitor cell, a class of cell types including myeloid progenitor cells and lymphoid progenitor cells.") -AnnotationAssertion( "haematopoietic progenitor cell differentiation") -AnnotationAssertion( "haemopoietic progenitor cell differentiation") -AnnotationAssertion( "hemopoietic progenitor cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002244") -AnnotationAssertion(rdfs:label "hematopoietic progenitor cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (wound healing involved in inflammatory response) - -AnnotationAssertion(Annotation( "GOC:jal") Annotation( "ISBN:0721601871") "The series of events that restore integrity to damaged tissue that contribute to an inflammatory response.") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") "healing during inflammatory response") -AnnotationAssertion(Annotation( "GOC:dph") "inflammatory response wound healing") -AnnotationAssertion( "GO:0002246") -AnnotationAssertion(rdfs:label "wound healing involved in inflammatory response") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (adaptive immune response) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GO_REF:0000022") Annotation( "ISBN:0781735149") "An immune response mediated by cells expressing specific receptors for antigens produced through a somatic diversification process, and allowing for an enhanced secondary response to subsequent exposures to the same antigen (immunological memory).") -AnnotationAssertion( "Wikipedia:Adaptive_immune_system") -AnnotationAssertion(Annotation( "ISBN:068340007X") "acquired immune response") -AnnotationAssertion(Annotation( "GOC:add") "immune memory response") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002250") -AnnotationAssertion(rdfs:label "adaptive immune response") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - # Class: (organ or tissue specific immune response) AnnotationAssertion(Annotation( "GOC:jal") Annotation( "GO_REF:0000022") "An immune response taking place in an organ or tissues such as the liver, brain, mucosa, or nervous system tissues.") @@ -47483,25 +20227,6 @@ AnnotationAssertion( "immune effector process") SubClassOf( ) -# Class: (lymphocyte homeostasis) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "PMID:15826826") Annotation( "PMID:16319493") Annotation( "PMID:16551252") Annotation( "PMID:16551262") "The process of regulating the proliferation and elimination of lymphocytes such that the total number of lymphocytes within a whole or part of an organism is stable over time in the absence of an outside stimulus.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002260") -AnnotationAssertion(rdfs:label "lymphocyte homeostasis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (myeloid cell homeostasis) - -AnnotationAssertion(Annotation( "CL:0000763") Annotation( "GOC:add") "The process of regulating the proliferation and elimination of myeloid cells such that the total number of myeloid cells within a whole or part of an organism is stable over time in the absence of an outside stimulus.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002262") -AnnotationAssertion(rdfs:label "myeloid cell homeostasis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - # Class: (cell activation involved in immune response) AnnotationAssertion(Annotation( "GOC:add") Annotation( "GO_REF:0000022") Annotation( "ISBN:0781735149") "A change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response.") @@ -47509,109 +20234,8 @@ AnnotationAssertion( "GOC:tb") "cell activation during immune response") AnnotationAssertion( "GO:0002263") AnnotationAssertion(rdfs:label "cell activation involved in immune response") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) SubClassOf( ) -# Class: (endothelial cell activation involved in immune response) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") "A change in the morphology or behavior of an endothelial cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response.") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:tb") "endothelial cell activation during immune response") -AnnotationAssertion( "GO:0002264") -AnnotationAssertion(rdfs:label "endothelial cell activation involved in immune response") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (astrocyte activation involved in immune response) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "PMID:11138785") "A change in the morphology or behavior of an astrocyte resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response.") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:tb") "astrocyte activation during immune response") -AnnotationAssertion( "GO:0002265") -AnnotationAssertion(rdfs:label "astrocyte activation involved in immune response") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (leukocyte activation involved in inflammatory response) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") "A change in the morphology or behavior of a leukocyte resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an inflammatory response.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "immune cell activation during inflammatory response") -AnnotationAssertion(Annotation( "GOC:tb") "leukocyte activation during inflammatory response") -AnnotationAssertion( "GO:0002269") -AnnotationAssertion(rdfs:label "leukocyte activation involved in inflammatory response") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (myeloid leukocyte activation) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") "A change in the morphology or behavior of a myeloid leukocyte resulting from exposure to an activating factor such as a cellular or soluble ligand.") -AnnotationAssertion( "myeloid leucocyte activation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002274") -AnnotationAssertion(rdfs:label "myeloid leukocyte activation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (myeloid cell activation involved in immune response) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") "A change in the morphology or behavior of a myeloid cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response.") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:tb") "myeloid cell activation during immune response") -AnnotationAssertion( "GO:0002275") -AnnotationAssertion(rdfs:label "myeloid cell activation involved in immune response") -SubClassOf( ) -SubClassOf( ) - -# Class: (myeloid dendritic cell activation involved in immune response) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") "The change in morphology and behavior of a myeloid dendritic cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:tb") "myeloid dendritic cell activation during immune response") -AnnotationAssertion( "GO:0002277") -AnnotationAssertion(rdfs:label "myeloid dendritic cell activation involved in immune response") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (monocyte activation involved in immune response) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") Annotation( "PMID:16551245") "The change in morphology and behavior of a monocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:tb") "monocyte activation during immune response") -AnnotationAssertion( "GO:0002280") -AnnotationAssertion(rdfs:label "monocyte activation involved in immune response") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (macrophage activation involved in immune response) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") "A change in morphology and behavior of a macrophage resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.") -AnnotationAssertion( "macrophage polarization involved in immune response") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:tb") "macrophage activation during immune response") -AnnotationAssertion( "GO:0002281") -AnnotationAssertion(rdfs:label "macrophage activation involved in immune response") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (neutrophil activation involved in immune response) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") "The change in morphology and behavior of a neutrophil resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:tb") "neutrophil activation during immune response") -AnnotationAssertion( "GO:0002283") -AnnotationAssertion(rdfs:label "neutrophil activation involved in immune response") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (myeloid dendritic cell differentiation involved in immune response) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") "The process in which an immature myeloid dendritic cell acquires the specialized features of a mature myeloid dendritic cell as part of an immune response.") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:tb") "myeloid dendritic cell differentiation during immune response") -AnnotationAssertion( "GO:0002284") -AnnotationAssertion(rdfs:label "myeloid dendritic cell differentiation involved in immune response") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (lymphocyte activation involved in immune response) AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") "A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.") @@ -47619,52 +20243,9 @@ AnnotationAssertion( "GOC:tb") "lymphocyte activation during immune response") AnnotationAssertion( "GO:0002285") AnnotationAssertion(rdfs:label "lymphocyte activation involved in immune response") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) -# Class: (T cell activation involved in immune response) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") "The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific, leading to the initiation or perpetuation of an immune response.") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:tb") "T cell activation during immune response") -AnnotationAssertion( "T lymphocyte activation during immune response") -AnnotationAssertion( "T-cell activation during immune response") -AnnotationAssertion( "T-lymphocyte activation during immune response") -AnnotationAssertion( "GO:0002286") -AnnotationAssertion(rdfs:label "T cell activation involved in immune response") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (T cell differentiation involved in immune response) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") "The process in which an antigenically naive T cell acquires the specialized features of an effector, regulatory, or memory T cell as part of an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells.") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:add") "T cell development involved in immune response") -AnnotationAssertion(Annotation( "GOC:tb") "T cell differentiation during immune response") -AnnotationAssertion( "T lymphocyte differentiation during immune response") -AnnotationAssertion( "T-cell differentiation during immune response") -AnnotationAssertion( "T-lymphocyte differentiation during immune response") -AnnotationAssertion( "GO:0002292") -AnnotationAssertion(rdfs:comment "Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.") -AnnotationAssertion(rdfs:label "T cell differentiation involved in immune response") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (T cell proliferation involved in immune response) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") "The expansion of a T cell population by cell division as part of an immune response.") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:tb") "T cell proliferation during immune response") -AnnotationAssertion( "T lymphocyte proliferation during immune response") -AnnotationAssertion( "T-cell proliferation during immune response") -AnnotationAssertion( "T-lymphocyte proliferation during immune response") -AnnotationAssertion( "GO:0002309") -AnnotationAssertion(rdfs:label "T cell proliferation involved in immune response") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (B cell activation involved in immune response) AnnotationAssertion(Annotation( "GOC:jal") "The change in morphology and behavior of a mature or immature B cell during an immune response, resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.") @@ -47675,7 +20256,6 @@ AnnotationAssertion( "B-lymphocyte activation during immune response") AnnotationAssertion( "GO:0002312") AnnotationAssertion(rdfs:label "B cell activation involved in immune response") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) @@ -47691,52 +20271,9 @@ AnnotationAssertion( "GO:0002313") AnnotationAssertion(rdfs:comment "Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.") AnnotationAssertion(rdfs:label "mature B cell differentiation involved in immune response") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) -# Class: (germinal center B cell differentiation) - -AnnotationAssertion(Annotation( "GOC:jal") Annotation( "ISBN:0781735149") "The process in which a B cell in the spleen acquires the specialized features of a germinal center B cell. Germinal center B cells are rapidly cycling B cells which have downregulated IgD expression and exhibit high levels of binding by peanut agglutinin (PNA).") -AnnotationAssertion( "germinal center B lymphocyte differentiation") -AnnotationAssertion( "germinal center B-cell differentiation") -AnnotationAssertion( "germinal center B-lymphocyte differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:add") "germinal center B cell development") -AnnotationAssertion( "GO:0002314") -AnnotationAssertion(rdfs:comment "Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.") -AnnotationAssertion(rdfs:label "germinal center B cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (marginal zone B cell differentiation) - -AnnotationAssertion(Annotation( "GOC:jal") Annotation( "ISBN:0781735149") "The process in which a B cell in the spleen acquires the specialized features of a marginal zone B cell. Marginal zone B cells are localized in a distinct anatomical region of the spleen that represents the major antigen-filtering and scavenging area (by specialized macrophages resident there). It appears that they are preselected to express a BCR repertoire similar to B-1 B cells, biased toward bacterial cell wall constituents and senescent self-components (such as oxidized LDL).") -AnnotationAssertion( "marginal zone B lymphocyte differentiation") -AnnotationAssertion( "marginal zone B-cell differentiation") -AnnotationAssertion( "marginal zone B-lymphocyte differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:add") "marginal zone B cell development") -AnnotationAssertion( "GO:0002315") -AnnotationAssertion(rdfs:comment "Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.") -AnnotationAssertion(rdfs:label "marginal zone B cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (follicular B cell differentiation) - -AnnotationAssertion(Annotation( "GOC:jal") Annotation( "ISBN:0781735149") "The process in which a B cell in the spleen acquires the specialized features of a follicular B cell. Follicular B cells are major population of mature recirculating B cells in the spleen and are located in the B-cell follicle region.") -AnnotationAssertion( "follicular B lymphocyte differentiation") -AnnotationAssertion( "follicular B-cell differentiation") -AnnotationAssertion( "follicular B-lymphocyte differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:add") "follicular B cell development") -AnnotationAssertion( "GO:0002316") -AnnotationAssertion(rdfs:comment "Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.") -AnnotationAssertion(rdfs:label "follicular B cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - # Class: (plasma cell differentiation) AnnotationAssertion(Annotation( "GOC:jal") "The process in which a B cell acquires the specialized features of a plasma cell. A plasma cell is a lymphocyte which develops from a B cell and produces high amounts of antibody.") @@ -47745,18 +20282,8 @@ AnnotationAssertion(Annotation( "GO:0002317") AnnotationAssertion(rdfs:comment "Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.") AnnotationAssertion(rdfs:label "plasma cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (myeloid progenitor cell differentiation) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "PMID:16551264") "The process in which a precursor cell type acquires the specialized features of a myeloid progenitor cell. Myeloid progenitor cells include progenitor cells for any of the myeloid lineages.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002318") -AnnotationAssertion(rdfs:label "myeloid progenitor cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - # Class: (memory B cell differentiation) AnnotationAssertion(Annotation( "GOC:jal") Annotation( "ISBN:0781735149") "The process in which a B cell acquires the specialized features of a memory B cell. Memory B cells are cells that can respond rapidly to antigen re-exposure by production of high-affinity antibody.") @@ -47768,84 +20295,9 @@ AnnotationAssertion(Annotation( "GO:0002319") AnnotationAssertion(rdfs:comment "Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.") AnnotationAssertion(rdfs:label "memory B cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) -# Class: (lymphoid progenitor cell differentiation) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "PMID:16551251") Annotation( "PMID:16551264") "The process in which a precursor cell type acquires the specialized features of a lymphoid progenitor cell. Lymphoid progenitor cells include progenitor cells for any of the lymphoid lineages.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002320") -AnnotationAssertion(rdfs:label "lymphoid progenitor cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (B cell proliferation involved in immune response) - -AnnotationAssertion(Annotation( "GOC:jal") "The expansion of a B cell population by cell division following B cell activation during an immune response.") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:tb") "B cell proliferation during immune response") -AnnotationAssertion( "B lymphocyte proliferation during immune response") -AnnotationAssertion( "B-cell proliferation during immune response") -AnnotationAssertion( "B-lymphocyte proliferation during immune response") -AnnotationAssertion( "GO:0002322") -AnnotationAssertion(rdfs:label "B cell proliferation involved in immune response") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (immature B cell differentiation) - -AnnotationAssertion(Annotation( "GOC:jal") Annotation( "ISBN:0781735149") Annotation( "PMID:16551251") "The process in which a precursor cell type acquires the specialized features of an immature B cell.") -AnnotationAssertion( "immature B lymphocyte differentiation") -AnnotationAssertion( "immature B-cell differentiation") -AnnotationAssertion( "immature B-lymphocyte differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:add") "immature B cell development") -AnnotationAssertion( "GO:0002327") -AnnotationAssertion(rdfs:comment "Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.") -AnnotationAssertion(rdfs:label "immature B cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (pro-B cell differentiation) - -AnnotationAssertion(Annotation( "GOC:jal") Annotation( "ISBN:0781735149") "The process in which a precursor cell type acquires the specialized features of a pro-B cell. Pro-B cells are the earliest stage of the B cell lineage and undergo heavy chain D and J gene rearrangements, although they are not fully committed.") -AnnotationAssertion( "pro-B lymphocyte differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:add") "pro-B cell development") -AnnotationAssertion( "GO:0002328") -AnnotationAssertion(rdfs:label "pro-B cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (pre-B cell differentiation) - -AnnotationAssertion(Annotation( "GOC:jal") Annotation( "ISBN:0781735149") "The process in which a precursor cell type acquires the specialized features of a pre-B cell. Pre-B cells follow the pro-B cell stage of immature B cell differentiation and undergo rearrangement of heavy chain V, D, and J gene segments.") -AnnotationAssertion( "pre-B lymphocyte differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:add") "pre-B cell development") -AnnotationAssertion( "GO:0002329") -AnnotationAssertion(rdfs:comment "Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.") -AnnotationAssertion(rdfs:label "pre-B cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (transitional stage B cell differentiation) - -AnnotationAssertion(Annotation( "GOC:jal") Annotation( "ISBN:0781735149") "The process in which immature B cells from the bone marrow become mature B cells in the spleen. Transitional stage B cells are subdivided into transitional one (T1) and transitional two (T2) stages and are short-lived and functionally incompetent.") -AnnotationAssertion( "transitional stage B lymphocyte differentiation") -AnnotationAssertion( "transitional stage B-cell differentiation") -AnnotationAssertion( "transitional stage B-lymphocyte differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:add") "transitional stage B cell development") -AnnotationAssertion( "GO:0002332") -AnnotationAssertion(rdfs:comment "Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.") -AnnotationAssertion(rdfs:label "transitional stage B cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - # Class: (mature B cell differentiation) AnnotationAssertion(Annotation( "GOC:jal") Annotation( "ISBN:0781735149") "The process in which transitional stage B cells acquire the specialized features of mature B cells in the spleen.") @@ -47857,75 +20309,8 @@ AnnotationAssertion(Annotation( "GO:0002335") AnnotationAssertion(rdfs:comment "Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.") AnnotationAssertion(rdfs:label "mature B cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (B cell selection) - -AnnotationAssertion(Annotation( "GOC:jal") "The process dependent upon B cell antigen receptor signaling in response to self or foreign antigen through which B cells are selected for survival.") -AnnotationAssertion( "B lymphocyte selection") -AnnotationAssertion( "B-cell selection") -AnnotationAssertion( "B-lymphocyte selection") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002339") -AnnotationAssertion(rdfs:label "B cell selection") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (peripheral B cell selection) - -AnnotationAssertion(Annotation( "GOC:jal") "Any B cell selection process that occurs in the periphery.") -AnnotationAssertion( "peripheral B lymphocyte selection") -AnnotationAssertion( "peripheral B-cell selection") -AnnotationAssertion( "peripheral B-lymphocyte selection") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002343") -AnnotationAssertion(rdfs:label "peripheral B cell selection") -SubClassOf( ) - -# Class: (B cell affinity maturation) - -AnnotationAssertion(Annotation( "GOC:jal") Annotation( "GO_REF:0000022") Annotation( "ISBN:0781735149") "The process in which B cells produce antibodies with increased antigen affinity. This is accomplished by somatic hypermutation and selection for B cells which produce higher affinity antibodies to antigen.") -AnnotationAssertion( "B lymphocyte affinity maturation") -AnnotationAssertion( "B-cell affinity maturation") -AnnotationAssertion( "B-lymphocyte affinity maturation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002344") -AnnotationAssertion(rdfs:label "B cell affinity maturation") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (histamine production involved in inflammatory response) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") Annotation( "PMID:16730260") "The synthesis or release of histamine following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels.") -AnnotationAssertion( "histamine production involved in acute inflammatory response") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002349") -AnnotationAssertion(rdfs:label "histamine production involved in inflammatory response") -SubClassOf( ) - -# Class: (serotonin production involved in inflammatory response) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") Annotation( "PMID:16730260") "The synthesis or release of serotonin following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels.") -AnnotationAssertion( "serotonin production involved in acute inflammatory response") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002351") -AnnotationAssertion(rdfs:label "serotonin production involved in inflammatory response") -SubClassOf( ) - -# Class: (B cell homeostatic proliferation) - -AnnotationAssertion(Annotation( "GOC:jal") "The non-specific expansion of B cell populations within a whole or part of an organism to reach to a total number of B cells which will then remain stable over time in the absence of an external stimulus.") -AnnotationAssertion( "B lymphocyte homeostatic proliferation") -AnnotationAssertion( "B-cell homeostatic proliferation") -AnnotationAssertion( "B-lymphocyte homeostatic proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002358") -AnnotationAssertion(rdfs:label "B cell homeostatic proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ) - # Class: (leukocyte activation involved in immune response) AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") "A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.") @@ -47935,79 +20320,7 @@ AnnotationAssertion( "GOC:tb") "leukocyte activation during immune response") AnnotationAssertion( "GO:0002366") AnnotationAssertion(rdfs:label "leukocyte activation involved in immune response") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -SubClassOf( ) - -# Class: (cytokine production involved in immune response) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GO_REF:0000022") Annotation( "ISBN:0781735149") "The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus contributing to an immune response, resulting in an increase in its intracellular or extracellular levels.") -AnnotationAssertion( "GO:0002374") -AnnotationAssertion( "GO:0002375") -AnnotationAssertion( "cytokine biosynthetic process involved in immune response") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") "cytokine production during immune response") -AnnotationAssertion(Annotation( "GOC:dph") "cytokine secretion during immune response") -AnnotationAssertion( "cytokine secretion involved in immune response") -AnnotationAssertion( "GO:0002367") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.") -AnnotationAssertion(rdfs:label "cytokine production involved in immune response") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (B cell cytokine production) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") "Any process that contributes to cytokine production by a B cell.") -AnnotationAssertion( "B lymphocyte cytokine production") -AnnotationAssertion( "B-cell cytokine production") -AnnotationAssertion( "B-lymphocyte cytokine production") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002368") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.") -AnnotationAssertion(rdfs:label "B cell cytokine production") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (T cell cytokine production) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") "Any process that contributes to cytokine production by a T cell.") -AnnotationAssertion( "T lymphocyte cytokine production") -AnnotationAssertion( "T-cell cytokine production") -AnnotationAssertion( "T-lymphocyte cytokine production") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002369") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.") -AnnotationAssertion(rdfs:label "T cell cytokine production") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (dendritic cell cytokine production) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") "Any process that contributes to cytokine production by a dendritic cell.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002371") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.") -AnnotationAssertion(rdfs:label "dendritic cell cytokine production") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (myeloid dendritic cell cytokine production) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") "Any process that contributes to cytokine production by a myeloid dendritic cell.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002372") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.") -AnnotationAssertion(rdfs:label "myeloid dendritic cell cytokine production") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) # Class: (immune system process) @@ -48045,110 +20358,16 @@ AnnotationAssertion(rdfs:comment "No AnnotationAssertion(rdfs:label "immunoglobulin production") SubClassOf( ) -# Class: (immunoglobulin production involved in immunoglobulin-mediated immune response) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") Annotation( "PMID:9185563") "The appearance of immunoglobulin due to biosynthesis or secretion following a cellular stimulus during an immune response, resulting in an increase in its intracellular or extracellular levels.") -AnnotationAssertion( "GO:0002379") -AnnotationAssertion( "GO:0002380") -AnnotationAssertion( "immunoglobulin production involved in immunoglobulin mediated immune response") -AnnotationAssertion( "immunoglobulin biosynthetic process involved in immune response") -AnnotationAssertion( "immunoglobulin secretion involved in immune response") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "antibody production during immune response") -AnnotationAssertion( "antibody secretion during immune response") -AnnotationAssertion(Annotation( "GOC:dph") "immunoglobulin production during immune response") -AnnotationAssertion(Annotation( "GOC:dph") "immunoglobulin production involved in immune response") -AnnotationAssertion( "GO:0002381") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.") -AnnotationAssertion(rdfs:label "immunoglobulin production involved in immunoglobulin-mediated immune response") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (hepatic immune response) AnnotationAssertion(Annotation( "GOC:jal") Annotation( "GO_REF:0000022") Annotation( "ISBN:0781735149") "An immune response taking place in the liver.") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0002384") AnnotationAssertion(rdfs:label "hepatic immune response") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectAllValuesFrom( )) -# Class: (immune response in gut-associated lymphoid tissue) - -AnnotationAssertion(Annotation( "GOC:jal") Annotation( "ISBN:0781735149") "Immune response taking place in the gut-associated lymphoid tissue (GALT). GALT includes Peyer's patches, appendix, and solitary lymph nodules.") -AnnotationAssertion( "immune response in GALT") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002387") -AnnotationAssertion(rdfs:label "immune response in gut-associated lymphoid tissue") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (immune response in Peyer's patch) - -AnnotationAssertion(Annotation( "GOC:jal") Annotation( "ISBN:0781735149") "Immune response taking place in the Peyer's patch, nodular lymphoid structures on the serosal surface of the small intestine.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002388") -AnnotationAssertion(rdfs:label "immune response in Peyer's patch") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - -# Class: (immune response in nasopharyngeal-associated lymphoid tissue) - -AnnotationAssertion(Annotation( "GOC:jal") Annotation( "ISBN:0781735149") "An immune response taking place in the nasopharyngeal-associated lymphoid tissue (NALT). NALT includes the tonsils and adenoids.") -AnnotationAssertion( "immune response in NALT") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002395") -AnnotationAssertion(rdfs:label "immune response in nasopharyngeal-associated lymphoid tissue") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (MHC protein complex assembly) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") Annotation( "PMID:15771591") Annotation( "PMID:15928678") "The aggregation, arrangement and bonding together of a set of components to form an MHC protein complex.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002396") -AnnotationAssertion(rdfs:label "MHC protein complex assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (MHC class II protein complex assembly) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") Annotation( "PMID:15771591") "The aggregation, arrangement and bonding together of a set of components to form an MHC class II protein complex.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002399") -AnnotationAssertion(rdfs:label "MHC class II protein complex assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (dendritic cell chemotaxis) - -AnnotationAssertion(Annotation( "CL:0000451") Annotation( "GOC:add") Annotation( "ISBN:0781735149") Annotation( "PMID:15814331") Annotation( "PMID:16056255") "The movement of a dendritic cell in response to an external stimulus.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002407") -AnnotationAssertion(rdfs:label "dendritic cell chemotaxis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (myeloid dendritic cell chemotaxis) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") Annotation( "PMID:15814331") Annotation( "PMID:16056255") "The movement of a myeloid dendritic cell in response to an external stimulus.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002408") -AnnotationAssertion(rdfs:label "myeloid dendritic cell chemotaxis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (Langerhans cell chemotaxis) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "PMID:16056255") Annotation( "PMID:16387601") "The movement of a Langerhans cell in response to an external stimulus.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002409") -AnnotationAssertion(rdfs:label "Langerhans cell chemotaxis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - # Class: (production of molecular mediator of immune response) AnnotationAssertion(Annotation( "GOC:add") Annotation( "GO_REF:0000022") Annotation( "ISBN:0781735149") "The synthesis or release of any molecular mediator of the immune response, resulting in an increase in its intracellular or extracellular levels.") @@ -48161,223 +20380,6 @@ AnnotationAssertion(rdfs:label "prod SubClassOf( ) SubClassOf( ) -# Class: (histamine secretion involved in inflammatory response) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") "The regulated release of histamine by a cell as part of an inflammatory response.") -AnnotationAssertion( "histamine secretion involved in acute inflammatory response") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002441") -AnnotationAssertion(rdfs:label "histamine secretion involved in inflammatory response") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (serotonin secretion involved in inflammatory response) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") "The regulated release of serotonin by a cell as part of an inflammatory response.") -AnnotationAssertion( "serotonin secretion involved in acute inflammatory response") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:tb") "serotonin release involved in inflammatory response") -AnnotationAssertion( "GO:0002442") -AnnotationAssertion(rdfs:label "serotonin secretion involved in inflammatory response") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (leukocyte mediated immunity) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GO_REF:0000022") Annotation( "ISBN:0781735149") "Any process involved in the carrying out of an immune response by a leukocyte.") -AnnotationAssertion( "GO:0019723") -AnnotationAssertion( "GO:0042087") -AnnotationAssertion( "immune cell effector process") -AnnotationAssertion( "immune cell mediated immunity") -AnnotationAssertion( "leucocyte immune effector process") -AnnotationAssertion( "leucocyte mediated immunity") -AnnotationAssertion( "leukocyte immune effector process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "cell-mediated immune response") -AnnotationAssertion( "cellular immune response") -AnnotationAssertion( "GO:0002443") -AnnotationAssertion(rdfs:label "leukocyte mediated immunity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - -# Class: (myeloid leukocyte mediated immunity) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GO_REF:0000022") Annotation( "ISBN:0781735149") "Any process involved in the carrying out of an immune response by a myeloid leukocyte.") -AnnotationAssertion( "myeloid leucocyte immune effector process") -AnnotationAssertion( "myeloid leucocyte mediated immunity") -AnnotationAssertion( "myeloid leukocyte immune effector process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002444") -AnnotationAssertion(rdfs:label "myeloid leukocyte mediated immunity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (neutrophil mediated immunity) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GO_REF:0000022") Annotation( "ISBN:0781735149") "Any process involved in the carrying out of an immune response by a neutrophil.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002446") -AnnotationAssertion(rdfs:label "neutrophil mediated immunity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (lymphocyte mediated immunity) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GO_REF:0000022") Annotation( "ISBN:0781735149") "Any process involved in the carrying out of an immune response by a lymphocyte.") -AnnotationAssertion( "cell-mediated immunity") -AnnotationAssertion( "cellular immune response") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002449") -AnnotationAssertion(rdfs:label "lymphocyte mediated immunity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (B cell antigen processing and presentation) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") Annotation( "PMID:15771591") "The process in which a B cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.") -AnnotationAssertion( "B lymphocyte antigen processing and presentation") -AnnotationAssertion( "B-cell antigen processing and presentation") -AnnotationAssertion( "B-lymphocyte antigen processing and presentation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002450") -AnnotationAssertion(rdfs:label "B cell antigen processing and presentation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (T cell mediated immunity) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GO_REF:0000022") Annotation( "ISBN:0781735149") "Any process involved in the carrying out of an immune response by a T cell.") -AnnotationAssertion( "cell-mediated immunity") -AnnotationAssertion( "cellular immune response") -AnnotationAssertion( "T lymphocyte mediated immunity") -AnnotationAssertion( "T-cell mediated immunity") -AnnotationAssertion( "T-lymphocyte mediated immunity") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002456") -AnnotationAssertion(rdfs:label "T cell mediated immunity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (T cell antigen processing and presentation) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "PMID:11417857") Annotation( "PMID:15120183") "The process in which a T cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.") -AnnotationAssertion( "T lymphocyte antigen processing and presentation") -AnnotationAssertion( "T-cell antigen processing and presentation") -AnnotationAssertion( "T-lymphocyte antigen processing and presentation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002457") -AnnotationAssertion(rdfs:label "T cell antigen processing and presentation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:mtg_sensu") Annotation( "ISBN:0781735149") Annotation( "ISBN:1405196831") "An immune response mediated by lymphocytes expressing specific receptors for antigen produced through a somatic diversification process that includes somatic recombination of germline gene segments encoding immunoglobulin superfamily domains. Recombined receptors for antigen encoded by immunoglobulin superfamily domains include T cell receptors and immunoglobulins (antibodies) produced by B cells. The first encounter with antigen elicits a primary immune response that is slow and not of great magnitude. T and B cells selected by antigen become activated and undergo clonal expansion. A fraction of antigen-reactive T and B cells become memory cells, whereas others differentiate into effector cells. The memory cells generated during the primary response enable a much faster and stronger secondary immune response upon subsequent exposures to the same antigen (immunological memory). An example of this is the adaptive immune response found in Mus musculus.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002460") -AnnotationAssertion(rdfs:label "adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains") -SubClassOf( ) - -# Class: (germinal center formation) - -AnnotationAssertion(Annotation( "GOC:jal") Annotation( "GO_REF:0000022") Annotation( "ISBN:081533642X") "The process in which germinal centers form. A germinal center is a specialized microenvironment formed when activated B cells enter lymphoid follicles. Germinal centers are the foci for B cell proliferation and somatic hypermutation.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002467") -AnnotationAssertion(rdfs:label "germinal center formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (dendritic cell antigen processing and presentation) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") Annotation( "PMID:15771591") "The process in which a dendritic cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002468") -AnnotationAssertion(rdfs:label "dendritic cell antigen processing and presentation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (myeloid dendritic cell antigen processing and presentation) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") Annotation( "PMID:15771591") "The process in which a myeloid dendritic cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002469") -AnnotationAssertion(rdfs:label "myeloid dendritic cell antigen processing and presentation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (monocyte antigen processing and presentation) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "PMID:11200054") "The process in which a monocyte expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002471") -AnnotationAssertion(rdfs:label "monocyte antigen processing and presentation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (macrophage antigen processing and presentation) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") Annotation( "PMID:15771591") "The process in which a macrophage expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002472") -AnnotationAssertion(rdfs:label "macrophage antigen processing and presentation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (antigen processing and presentation of peptide antigen via MHC class II) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") Annotation( "PMID:15531770") Annotation( "PMID:15771591") "The process in which an antigen-presenting cell expresses a peptide antigen on its cell surface in association with an MHC class II protein complex. The peptide antigen is typically, but not always, processed from a whole protein.") -AnnotationAssertion( "peptide antigen processing and presentation via MHC class II") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002495") -AnnotationAssertion(rdfs:label "antigen processing and presentation of peptide antigen via MHC class II") -SubClassOf( ) -SubClassOf( ) - -# Class: (proteolysis associated with antigen processing and presentation) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") Annotation( "PMID:15224092") Annotation( "PMID:15771591") "The hydrolysis of a peptide bond or bonds within a protein contributing to antigen processing and presentation.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002496") -AnnotationAssertion(rdfs:label "proteolysis associated with antigen processing and presentation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (proteolysis within lysosome associated with antigen processing and presentation) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") Annotation( "PMID:15771591") "The hydrolysis of a peptide bond or bonds within a protein by lysosomal resident proteases contributing to antigen processing and presentation.") -AnnotationAssertion( "lysosomal proteolysis associated with antigen processing and presentation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002500") -AnnotationAssertion(rdfs:label "proteolysis within lysosome associated with antigen processing and presentation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (antigen processing and presentation of peptide or polysaccharide antigen via MHC class II) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") Annotation( "PMID:15531770") Annotation( "PMID:15771591") Annotation( "PMID:16153240") "The process in which an antigen-presenting cell expresses antigen (peptide or polysaccharide) on its cell surface in association with an MHC class II protein complex.") -AnnotationAssertion( "peptide or polysaccharide antigen processing and presentation of via MHC class II") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002504") -AnnotationAssertion(rdfs:label "antigen processing and presentation of peptide or polysaccharide antigen via MHC class II") -SubClassOf( ) - -# Class: (immune system development) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:dph") "The process whose specific outcome is the progression of an organismal system whose objective is to provide calibrated responses by an organism to a potential internal or invasive threat, over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002520") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "immune system development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - # Class: (leukocyte differentiation) AnnotationAssertion(Annotation( "CL:0000738") Annotation( "GOC:add") Annotation( "PMID:16551264") "The process in which a relatively unspecialized hemopoietic precursor cell acquires the specialized features of a leukocyte. A leukocyte is an achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue.") @@ -48386,1281 +20388,9 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0002521") AnnotationAssertion(rdfs:label "leukocyte differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (leukocyte migration involved in immune response) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") Annotation( "PMID:14680625") Annotation( "PMID:14708592") Annotation( "PMID:7507411") Annotation( "PMID:8600538") "The movement of a leukocyte within or between different tissues and organs of the body as part of an immune response.") -AnnotationAssertion( "immune cell migration during immune response") -AnnotationAssertion( "immune cell trafficking during immune response") -AnnotationAssertion( "leucocyte migration during immune response") -AnnotationAssertion( "leucocyte trafficking during immune response") -AnnotationAssertion( "leukocyte trafficking during immune response") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002522") -AnnotationAssertion(rdfs:label "leukocyte migration involved in immune response") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (leukocyte migration involved in inflammatory response) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") Annotation( "PMID:14680625") Annotation( "PMID:14708592") Annotation( "PMID:7507411") Annotation( "PMID:8600538") "The movement of a leukocyte within or between different tissues and organs of the body contributing to an inflammatory response.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "immune cell migration during inflammatory response") -AnnotationAssertion( "immune cell trafficking during inflammatory response") -AnnotationAssertion( "leucocyte migration during inflammatory response") -AnnotationAssertion( "leucocyte trafficking during inflammatory response") -AnnotationAssertion(Annotation( "GOC:dph") "leukocyte migration during inflammatory response") -AnnotationAssertion( "leukocyte trafficking during inflammatory response") -AnnotationAssertion( "GO:0002523") -AnnotationAssertion(rdfs:label "leukocyte migration involved in inflammatory response") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (production of molecular mediator involved in inflammatory response) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:dph") Annotation( "GOC:tb") Annotation( "ISBN:0781735149") "The synthesis or release of any molecular mediator of the inflammatory response following an inflammatory stimulus, resulting in an increase in its intracellular or extracellular levels.") -AnnotationAssertion( "production of molecular mediator involved in acute inflammatory response") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "production of cellular mediator of acute inflammation") -AnnotationAssertion( "GO:0002532") -AnnotationAssertion(rdfs:label "production of molecular mediator involved in inflammatory response") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cytokine production involved in inflammatory response) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") "The synthesis or release of a cytokine following a inflammatory stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels.") -AnnotationAssertion( "cytokine production involved in acute inflammatory response") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002534") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "cytokine production involved in inflammatory response") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (monocyte chemotaxis) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "PMID:11696603") Annotation( "PMID:15173832") "The movement of a monocyte in response to an external stimulus.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002548") -AnnotationAssertion(rdfs:label "monocyte chemotaxis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (serotonin secretion by platelet) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") "The regulated release of serotonin by a platelet or group of platelets.") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:tb") "serotonin release by platelet") -AnnotationAssertion( "GO:0002554") -AnnotationAssertion(rdfs:label "serotonin secretion by platelet") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (histamine secretion by platelet) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "PMID:9117517") "The regulated release of histamine by a platelet or group of platelets.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002555") -AnnotationAssertion(rdfs:label "histamine secretion by platelet") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (somatic diversification of immune receptors via germline recombination within a single locus) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") Annotation( "PMID:16102575") Annotation( "PMID:16166509") "The process in which immune receptor genes are diversified through recombination of the germline genetic elements within a single genetic locus.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002562") -AnnotationAssertion(rdfs:label "somatic diversification of immune receptors via germline recombination within a single locus") -SubClassOf( ) -SubClassOf( ) - -# Class: (somatic diversification of immune receptors via somatic mutation) - -AnnotationAssertion(Annotation( "ISBN:0781735149") Annotation( "PMID:16102575") "The process in which immune receptor genes are diversified through somatic mutation.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002566") -AnnotationAssertion(rdfs:label "somatic diversification of immune receptors via somatic mutation") -SubClassOf( ) - -# Class: (pro-T cell differentiation) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") "The process in which a precursor cell type acquires the specialized features of a pro-T cell. Pro-T cells are the earliest stage of the T cell lineage but are not fully committed.") -AnnotationAssertion( "pro-T lymphocyte differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002572") -AnnotationAssertion(rdfs:label "pro-T cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (myeloid leukocyte differentiation) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "PMID:16551251") "The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of any cell of the myeloid leukocyte lineage.") -AnnotationAssertion( "myeloid leucocyte differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002573") -AnnotationAssertion(rdfs:label "myeloid leukocyte differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (thrombocyte differentiation) - -AnnotationAssertion(Annotation( "GOC:add") "The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a thrombocyte, a nucleated cell found in all vertebrates but mammals involved in hemostasis.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002574") -AnnotationAssertion(rdfs:comment "Note that platelets are the non-nucleated mammalian functional equivalent of the nucleated thrombocytes of non-mammalian vertebrates and are sometimes also referred to as thrombocytes. Platelet formation in mammals is covered by the biological_process term platelet formation ; GO:0030220.") -AnnotationAssertion(rdfs:label "thrombocyte differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (platelet degranulation) - -AnnotationAssertion(Annotation( "GOC:add") "The regulated exocytosis of secretory granules containing preformed mediators such as histamine and serotonin by a platelet.") -AnnotationAssertion( "platelet exocytosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002576") -AnnotationAssertion(rdfs:label "platelet degranulation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of antigen processing and presentation) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that modulates the frequency, rate, or extent of antigen processing and presentation.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002577") -AnnotationAssertion(rdfs:label "regulation of antigen processing and presentation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of antigen processing and presentation) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation.") -AnnotationAssertion( "down regulation of antigen processing and presentation") -AnnotationAssertion( "down-regulation of antigen processing and presentation") -AnnotationAssertion( "downregulation of antigen processing and presentation") -AnnotationAssertion( "inhibition of antigen processing and presentation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002578") -AnnotationAssertion(rdfs:label "negative regulation of antigen processing and presentation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of antigen processing and presentation) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation.") -AnnotationAssertion( "up regulation of antigen processing and presentation") -AnnotationAssertion( "up-regulation of antigen processing and presentation") -AnnotationAssertion( "upregulation of antigen processing and presentation") -AnnotationAssertion( "activation of antigen processing and presentation") -AnnotationAssertion( "stimulation of antigen processing and presentation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002579") -AnnotationAssertion(rdfs:label "positive regulation of antigen processing and presentation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that modulates the frequency, rate, or extent of antigen processing and presentation of antigen (peptide or polysaccharide) via MHC class II.") -AnnotationAssertion( "regulation of peptide or polysaccharide antigen processing and presentation via MHC class II") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002580") -AnnotationAssertion(rdfs:label "regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of antigen (peptide or polysaccharide) via MHC class II.") -AnnotationAssertion( "down regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II") -AnnotationAssertion( "down-regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II") -AnnotationAssertion( "downregulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II") -AnnotationAssertion( "negative regulation of peptide or polysaccharide antigen processing and presentation via MHC class II") -AnnotationAssertion( "inhibition of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002581") -AnnotationAssertion(rdfs:label "negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of antigen (peptide or polysaccharide) via MHC class II.") -AnnotationAssertion( "positive regulation of peptide or polysaccharide antigen processing and presentation via MHC class II") -AnnotationAssertion( "up regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II") -AnnotationAssertion( "up-regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II") -AnnotationAssertion( "upregulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II") -AnnotationAssertion( "activation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II") -AnnotationAssertion( "stimulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002582") -AnnotationAssertion(rdfs:label "positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of antigen processing and presentation of peptide antigen) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that modulates the frequency, rate, or extent of antigen processing and presentation of peptide antigen.") -AnnotationAssertion( "regulation of peptide antigen processing and presentation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002583") -AnnotationAssertion(rdfs:label "regulation of antigen processing and presentation of peptide antigen") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of antigen processing and presentation of peptide antigen) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of peptide antigen.") -AnnotationAssertion( "down regulation of antigen processing and presentation of peptide antigen") -AnnotationAssertion( "down-regulation of antigen processing and presentation of peptide antigen") -AnnotationAssertion( "downregulation of antigen processing and presentation of peptide antigen") -AnnotationAssertion( "negative regulation of peptide antigen processing and presentation") -AnnotationAssertion( "inhibition of antigen processing and presentation of peptide antigen") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002584") -AnnotationAssertion(rdfs:label "negative regulation of antigen processing and presentation of peptide antigen") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of antigen processing and presentation of peptide antigen) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of peptide antigen.") -AnnotationAssertion( "positive regulation of peptide antigen processing and presentation") -AnnotationAssertion( "up regulation of antigen processing and presentation of peptide antigen") -AnnotationAssertion( "up-regulation of antigen processing and presentation of peptide antigen") -AnnotationAssertion( "upregulation of antigen processing and presentation of peptide antigen") -AnnotationAssertion( "activation of antigen processing and presentation of peptide antigen") -AnnotationAssertion( "stimulation of antigen processing and presentation of peptide antigen") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002585") -AnnotationAssertion(rdfs:label "positive regulation of antigen processing and presentation of peptide antigen") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of antigen processing and presentation of peptide antigen via MHC class II) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that modulates the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class II.") -AnnotationAssertion( "regulation of peptide antigen processing and presentation via MHC class II") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002586") -AnnotationAssertion(rdfs:label "regulation of antigen processing and presentation of peptide antigen via MHC class II") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of antigen processing and presentation of peptide antigen via MHC class II) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class II.") -AnnotationAssertion( "down regulation of antigen processing and presentation of peptide antigen via MHC class II") -AnnotationAssertion( "down-regulation of antigen processing and presentation of peptide antigen via MHC class II") -AnnotationAssertion( "downregulation of antigen processing and presentation of peptide antigen via MHC class II") -AnnotationAssertion( "negative regulation of peptide antigen processing and presentation via MHC class II") -AnnotationAssertion( "inhibition of antigen processing and presentation of peptide antigen via MHC class II") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002587") -AnnotationAssertion(rdfs:label "negative regulation of antigen processing and presentation of peptide antigen via MHC class II") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of antigen processing and presentation of peptide antigen via MHC class II) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class II.") -AnnotationAssertion( "positive regulation of peptide antigen processing and presentation via MHC class II") -AnnotationAssertion( "up regulation of antigen processing and presentation of peptide antigen via MHC class II") -AnnotationAssertion( "up-regulation of antigen processing and presentation of peptide antigen via MHC class II") -AnnotationAssertion( "upregulation of antigen processing and presentation of peptide antigen via MHC class II") -AnnotationAssertion( "activation of antigen processing and presentation of peptide antigen via MHC class II") -AnnotationAssertion( "stimulation of antigen processing and presentation of peptide antigen via MHC class II") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002588") -AnnotationAssertion(rdfs:label "positive regulation of antigen processing and presentation of peptide antigen via MHC class II") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of dendritic cell antigen processing and presentation) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that modulates the frequency, rate, or extent of dendritic cell antigen processing and presentation.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002604") -AnnotationAssertion(rdfs:label "regulation of dendritic cell antigen processing and presentation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of dendritic cell antigen processing and presentation) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that stops, prevents, or reduces the frequency, rate, or extent of dendritic cell antigen processing and presentation.") -AnnotationAssertion( "down regulation of dendritic cell antigen processing and presentation") -AnnotationAssertion( "down-regulation of dendritic cell antigen processing and presentation") -AnnotationAssertion( "downregulation of dendritic cell antigen processing and presentation") -AnnotationAssertion( "inhibition of dendritic cell antigen processing and presentation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002605") -AnnotationAssertion(rdfs:label "negative regulation of dendritic cell antigen processing and presentation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of dendritic cell antigen processing and presentation) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that activates or increases the frequency, rate, or extent of dendritic cell antigen processing and presentation.") -AnnotationAssertion( "up regulation of dendritic cell antigen processing and presentation") -AnnotationAssertion( "up-regulation of dendritic cell antigen processing and presentation") -AnnotationAssertion( "upregulation of dendritic cell antigen processing and presentation") -AnnotationAssertion( "activation of dendritic cell antigen processing and presentation") -AnnotationAssertion( "stimulation of dendritic cell antigen processing and presentation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002606") -AnnotationAssertion(rdfs:label "positive regulation of dendritic cell antigen processing and presentation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of myeloid dendritic cell antigen processing and presentation) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that modulates the frequency, rate, or extent of myeloid dendritic cell antigen processing and presentation.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002607") -AnnotationAssertion(rdfs:label "regulation of myeloid dendritic cell antigen processing and presentation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of myeloid dendritic cell antigen processing and presentation) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid dendritic cell antigen processing and presentation.") -AnnotationAssertion( "down regulation of myeloid dendritic cell antigen processing and presentation") -AnnotationAssertion( "down-regulation of myeloid dendritic cell antigen processing and presentation") -AnnotationAssertion( "downregulation of myeloid dendritic cell antigen processing and presentation") -AnnotationAssertion( "inhibition of myeloid dendritic cell antigen processing and presentation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002608") -AnnotationAssertion(rdfs:label "negative regulation of myeloid dendritic cell antigen processing and presentation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of myeloid dendritic cell antigen processing and presentation) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that activates or increases the frequency, rate, or extent of myeloid dendritic cell antigen processing and presentation.") -AnnotationAssertion( "up regulation of myeloid dendritic cell antigen processing and presentation") -AnnotationAssertion( "up-regulation of myeloid dendritic cell antigen processing and presentation") -AnnotationAssertion( "upregulation of myeloid dendritic cell antigen processing and presentation") -AnnotationAssertion( "activation of myeloid dendritic cell antigen processing and presentation") -AnnotationAssertion( "stimulation of myeloid dendritic cell antigen processing and presentation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002609") -AnnotationAssertion(rdfs:label "positive regulation of myeloid dendritic cell antigen processing and presentation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of monocyte antigen processing and presentation) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that modulates the frequency, rate, or extent of monocyte antigen processing and presentation.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002613") -AnnotationAssertion(rdfs:label "regulation of monocyte antigen processing and presentation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of monocyte antigen processing and presentation) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that stops, prevents, or reduces the frequency, rate, or extent of monocyte antigen processing and presentation.") -AnnotationAssertion( "down regulation of monocyte antigen processing and presentation") -AnnotationAssertion( "down-regulation of monocyte antigen processing and presentation") -AnnotationAssertion( "downregulation of monocyte antigen processing and presentation") -AnnotationAssertion( "inhibition of monocyte antigen processing and presentation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002614") -AnnotationAssertion(rdfs:label "negative regulation of monocyte antigen processing and presentation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of monocyte antigen processing and presentation) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that activates or increases the frequency, rate, or extent of monocyte antigen processing and presentation.") -AnnotationAssertion( "up regulation of monocyte antigen processing and presentation") -AnnotationAssertion( "up-regulation of monocyte antigen processing and presentation") -AnnotationAssertion( "upregulation of monocyte antigen processing and presentation") -AnnotationAssertion( "activation of monocyte antigen processing and presentation") -AnnotationAssertion( "stimulation of monocyte antigen processing and presentation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002615") -AnnotationAssertion(rdfs:label "positive regulation of monocyte antigen processing and presentation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of macrophage antigen processing and presentation) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that modulates the frequency, rate, or extent of macrophage antigen processing and presentation.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002616") -AnnotationAssertion(rdfs:label "regulation of macrophage antigen processing and presentation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of macrophage antigen processing and presentation) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that stops, prevents, or reduces the frequency, rate, or extent of macrophage antigen processing and presentation.") -AnnotationAssertion( "down regulation of macrophage antigen processing and presentation") -AnnotationAssertion( "down-regulation of macrophage antigen processing and presentation") -AnnotationAssertion( "downregulation of macrophage antigen processing and presentation") -AnnotationAssertion( "inhibition of macrophage antigen processing and presentation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002617") -AnnotationAssertion(rdfs:label "negative regulation of macrophage antigen processing and presentation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of macrophage antigen processing and presentation) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that activates or increases the frequency, rate, or extent of macrophage antigen processing and presentation.") -AnnotationAssertion( "up regulation of macrophage antigen processing and presentation") -AnnotationAssertion( "up-regulation of macrophage antigen processing and presentation") -AnnotationAssertion( "upregulation of macrophage antigen processing and presentation") -AnnotationAssertion( "activation of macrophage antigen processing and presentation") -AnnotationAssertion( "stimulation of macrophage antigen processing and presentation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002618") -AnnotationAssertion(rdfs:label "positive regulation of macrophage antigen processing and presentation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of B cell antigen processing and presentation) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that modulates the frequency, rate, or extent of B cell antigen processing and presentation.") -AnnotationAssertion( "regulation of B lymphocyte antigen processing and presentation") -AnnotationAssertion( "regulation of B-cell antigen processing and presentation") -AnnotationAssertion( "regulation of B-lymphocyte antigen processing and presentation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002622") -AnnotationAssertion(rdfs:label "regulation of B cell antigen processing and presentation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (negative regulation of B cell antigen processing and presentation) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell antigen processing and presentation.") -AnnotationAssertion( "down regulation of B cell antigen processing and presentation") -AnnotationAssertion( "down-regulation of B cell antigen processing and presentation") -AnnotationAssertion( "downregulation of B cell antigen processing and presentation") -AnnotationAssertion( "negative regulation of B lymphocyte antigen processing and presentation") -AnnotationAssertion( "negative regulation of B-cell antigen processing and presentation") -AnnotationAssertion( "negative regulation of B-lymphocyte antigen processing and presentation") -AnnotationAssertion( "inhibition of B cell antigen processing and presentation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002623") -AnnotationAssertion(rdfs:label "negative regulation of B cell antigen processing and presentation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of B cell antigen processing and presentation) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that activates or increases the frequency, rate, or extent of B cell antigen processing and presentation.") -AnnotationAssertion( "positive regulation of B lymphocyte antigen processing and presentation") -AnnotationAssertion( "positive regulation of B-cell antigen processing and presentation") -AnnotationAssertion( "positive regulation of B-lymphocyte antigen processing and presentation") -AnnotationAssertion( "up regulation of B cell antigen processing and presentation") -AnnotationAssertion( "up-regulation of B cell antigen processing and presentation") -AnnotationAssertion( "upregulation of B cell antigen processing and presentation") -AnnotationAssertion( "activation of B cell antigen processing and presentation") -AnnotationAssertion( "stimulation of B cell antigen processing and presentation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002624") -AnnotationAssertion(rdfs:label "positive regulation of B cell antigen processing and presentation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of T cell antigen processing and presentation) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that modulates the frequency, rate, or extent of T cell antigen processing and presentation.") -AnnotationAssertion( "regulation of T lymphocyte antigen processing and presentation") -AnnotationAssertion( "regulation of T-cell antigen processing and presentation") -AnnotationAssertion( "regulation of T-lymphocyte antigen processing and presentation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002625") -AnnotationAssertion(rdfs:label "regulation of T cell antigen processing and presentation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (negative regulation of T cell antigen processing and presentation) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell antigen processing and presentation.") -AnnotationAssertion( "down regulation of T cell antigen processing and presentation") -AnnotationAssertion( "down-regulation of T cell antigen processing and presentation") -AnnotationAssertion( "downregulation of T cell antigen processing and presentation") -AnnotationAssertion( "negative regulation of T lymphocyte antigen processing and presentation") -AnnotationAssertion( "negative regulation of T-cell antigen processing and presentation") -AnnotationAssertion( "negative regulation of T-lymphocyte antigen processing and presentation") -AnnotationAssertion( "inhibition of T cell antigen processing and presentation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002626") -AnnotationAssertion(rdfs:label "negative regulation of T cell antigen processing and presentation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of T cell antigen processing and presentation) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that activates or increases the frequency, rate, or extent of T cell antigen processing and presentation.") -AnnotationAssertion( "positive regulation of T lymphocyte antigen processing and presentation") -AnnotationAssertion( "positive regulation of T-cell antigen processing and presentation") -AnnotationAssertion( "positive regulation of T-lymphocyte antigen processing and presentation") -AnnotationAssertion( "up regulation of T cell antigen processing and presentation") -AnnotationAssertion( "up-regulation of T cell antigen processing and presentation") -AnnotationAssertion( "upregulation of T cell antigen processing and presentation") -AnnotationAssertion( "activation of T cell antigen processing and presentation") -AnnotationAssertion( "stimulation of T cell antigen processing and presentation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002627") -AnnotationAssertion(rdfs:label "positive regulation of T cell antigen processing and presentation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (regulation of proteolysis associated with antigen processing and presentation) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that modulates the frequency, rate, or extent of proteolysis associated with antigen processing and presentation.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002628") -AnnotationAssertion(rdfs:label "regulation of proteolysis associated with antigen processing and presentation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of proteolysis associated with antigen processing and presentation) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that stops, prevents, or reduces the frequency, rate, or extent of proteolysis associated with antigen processing and presentation.") -AnnotationAssertion( "down regulation of proteolysis associated with antigen processing and presentation") -AnnotationAssertion( "down-regulation of proteolysis associated with antigen processing and presentation") -AnnotationAssertion( "downregulation of proteolysis associated with antigen processing and presentation") -AnnotationAssertion( "inhibition of proteolysis associated with antigen processing and presentation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002629") -AnnotationAssertion(rdfs:label "negative regulation of proteolysis associated with antigen processing and presentation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of proteolysis associated with antigen processing and presentation) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that activates or increases the frequency, rate, or extent of proteolysis associated with antigen processing and presentation.") -AnnotationAssertion( "up regulation of proteolysis associated with antigen processing and presentation") -AnnotationAssertion( "up-regulation of proteolysis associated with antigen processing and presentation") -AnnotationAssertion( "upregulation of proteolysis associated with antigen processing and presentation") -AnnotationAssertion( "activation of proteolysis associated with antigen processing and presentation") -AnnotationAssertion( "stimulation of proteolysis associated with antigen processing and presentation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002630") -AnnotationAssertion(rdfs:label "positive regulation of proteolysis associated with antigen processing and presentation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (regulation of germinal center formation) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that modulates the frequency, rate, or extent of germinal center formation.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002634") -AnnotationAssertion(rdfs:label "regulation of germinal center formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (negative regulation of germinal center formation) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that stops, prevents, or reduces the frequency, rate, or extent of germinal center formation.") -AnnotationAssertion( "down regulation of germinal center formation") -AnnotationAssertion( "down-regulation of germinal center formation") -AnnotationAssertion( "downregulation of germinal center formation") -AnnotationAssertion( "inhibition of germinal center formation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002635") -AnnotationAssertion(rdfs:label "negative regulation of germinal center formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of germinal center formation) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that activates or increases the frequency, rate, or extent of germinal center formation.") -AnnotationAssertion( "up regulation of germinal center formation") -AnnotationAssertion( "up-regulation of germinal center formation") -AnnotationAssertion( "upregulation of germinal center formation") -AnnotationAssertion( "activation of germinal center formation") -AnnotationAssertion( "stimulation of germinal center formation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002636") -AnnotationAssertion(rdfs:label "positive regulation of germinal center formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of immunoglobulin production) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that modulates the frequency, rate, or extent of immunoglobulin production.") -AnnotationAssertion( "GO:0002640") -AnnotationAssertion( "GO:0051023") -AnnotationAssertion( "regulation of antibody production") -AnnotationAssertion( "regulation of immunoglobulin biosynthetic process") -AnnotationAssertion( "regulation of immunoglobulin secretion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002637") -AnnotationAssertion(rdfs:label "regulation of immunoglobulin production") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (negative regulation of immunoglobulin production) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that stops, prevents, or reduces the frequency, rate, or extent of immunoglobulin production.") -AnnotationAssertion( "GO:0002641") -AnnotationAssertion( "GO:0051025") -AnnotationAssertion( "down regulation of immunoglobulin production") -AnnotationAssertion( "down-regulation of immunoglobulin production") -AnnotationAssertion( "downregulation of immunoglobulin production") -AnnotationAssertion( "inhibition of immunoglobulin production") -AnnotationAssertion( "negative regulation of immunoglobulin biosynthetic process") -AnnotationAssertion( "negative regulation of immunoglobulin secretion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002638") -AnnotationAssertion(rdfs:label "negative regulation of immunoglobulin production") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of immunoglobulin production) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that activates or increases the frequency, rate, or extent of immunoglobulin production.") -AnnotationAssertion( "GO:0002642") -AnnotationAssertion( "GO:0051024") -AnnotationAssertion( "up regulation of immunoglobulin production") -AnnotationAssertion( "up-regulation of immunoglobulin production") -AnnotationAssertion( "upregulation of immunoglobulin production") -AnnotationAssertion( "activation of immunoglobulin production") -AnnotationAssertion( "positive regulation of immunoglobulin biosynthetic process") -AnnotationAssertion( "positive regulation of immunoglobulin secretion") -AnnotationAssertion( "stimulation of immunoglobulin production") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002639") -AnnotationAssertion(rdfs:label "positive regulation of immunoglobulin production") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of immune system process) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that modulates the frequency, rate, or extent of an immune system process.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002682") -AnnotationAssertion(rdfs:label "regulation of immune system process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (negative regulation of immune system process) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune system process.") -AnnotationAssertion( "down regulation of immune system process") -AnnotationAssertion( "down-regulation of immune system process") -AnnotationAssertion( "downregulation of immune system process") -AnnotationAssertion( "inhibition of immune system process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002683") -AnnotationAssertion(rdfs:label "negative regulation of immune system process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of immune system process) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that activates or increases the frequency, rate, or extent of an immune system process.") -AnnotationAssertion( "up regulation of immune system process") -AnnotationAssertion( "up-regulation of immune system process") -AnnotationAssertion( "upregulation of immune system process") -AnnotationAssertion( "activation of immune system process") -AnnotationAssertion( "stimulation of immune system process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002684") -AnnotationAssertion(rdfs:label "positive regulation of immune system process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of leukocyte migration) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that modulates the frequency, rate, or extent of leukocyte migration.") -AnnotationAssertion( "regulation of immune cell migration") -AnnotationAssertion( "regulation of leucocyte migration") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002685") -AnnotationAssertion(rdfs:label "regulation of leukocyte migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of leukocyte migration) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte migration.") -AnnotationAssertion( "down regulation of leukocyte migration") -AnnotationAssertion( "down-regulation of leukocyte migration") -AnnotationAssertion( "downregulation of leukocyte migration") -AnnotationAssertion( "negative regulation of immune cell migration") -AnnotationAssertion( "negative regulation of leucocyte migration") -AnnotationAssertion( "inhibition of leukocyte migration") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002686") -AnnotationAssertion(rdfs:label "negative regulation of leukocyte migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of leukocyte migration) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that activates or increases the frequency, rate, or extent of leukocyte migration.") -AnnotationAssertion( "positive regulation of immune cell migration") -AnnotationAssertion( "positive regulation of leucocyte migration") -AnnotationAssertion( "up regulation of leukocyte migration") -AnnotationAssertion( "up-regulation of leukocyte migration") -AnnotationAssertion( "upregulation of leukocyte migration") -AnnotationAssertion( "activation of leukocyte migration") -AnnotationAssertion( "stimulation of leukocyte migration") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002687") -AnnotationAssertion(rdfs:label "positive regulation of leukocyte migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of leukocyte chemotaxis) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that modulates the frequency, rate, or extent of leukocyte chemotaxis.") -AnnotationAssertion( "regulation of immune cell chemotaxis") -AnnotationAssertion( "regulation of leucocyte chemotaxis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002688") -AnnotationAssertion(rdfs:label "regulation of leukocyte chemotaxis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of leukocyte chemotaxis) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte chemotaxis.") -AnnotationAssertion( "down regulation of leukocyte chemotaxis") -AnnotationAssertion( "down-regulation of leukocyte chemotaxis") -AnnotationAssertion( "downregulation of leukocyte chemotaxis") -AnnotationAssertion( "negative regulation of immune cell chemotaxis") -AnnotationAssertion( "negative regulation of leucocyte chemotaxis") -AnnotationAssertion( "inhibition of leukocyte chemotaxis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002689") -AnnotationAssertion(rdfs:label "negative regulation of leukocyte chemotaxis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of leukocyte chemotaxis) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that activates or increases the frequency, rate, or extent of leukocyte chemotaxis.") -AnnotationAssertion( "positive regulation of immune cell chemotaxis") -AnnotationAssertion( "positive regulation of leucocyte chemotaxis") -AnnotationAssertion( "up regulation of leukocyte chemotaxis") -AnnotationAssertion( "up-regulation of leukocyte chemotaxis") -AnnotationAssertion( "upregulation of leukocyte chemotaxis") -AnnotationAssertion( "activation of leukocyte chemotaxis") -AnnotationAssertion( "stimulation of leukocyte chemotaxis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002690") -AnnotationAssertion(rdfs:label "positive regulation of leukocyte chemotaxis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of leukocyte activation) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that modulates the frequency, rate, or extent of leukocyte activation.") -AnnotationAssertion( "regulation of immune cell activation") -AnnotationAssertion( "regulation of leucocyte activation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002694") -AnnotationAssertion(rdfs:label "regulation of leukocyte activation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of leukocyte activation) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte activation.") -AnnotationAssertion( "down regulation of leukocyte activation") -AnnotationAssertion( "down-regulation of leukocyte activation") -AnnotationAssertion( "downregulation of leukocyte activation") -AnnotationAssertion( "negative regulation of immune cell activation") -AnnotationAssertion( "negative regulation of leucocyte activation") -AnnotationAssertion( "inhibition of leukocyte activation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002695") -AnnotationAssertion(rdfs:label "negative regulation of leukocyte activation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of leukocyte activation) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that activates or increases the frequency, rate, or extent of leukocyte activation.") -AnnotationAssertion( "positive regulation of immune cell activation") -AnnotationAssertion( "positive regulation of leucocyte activation") -AnnotationAssertion( "up regulation of leukocyte activation") -AnnotationAssertion( "up-regulation of leukocyte activation") -AnnotationAssertion( "upregulation of leukocyte activation") -AnnotationAssertion( "activation of leukocyte activation") -AnnotationAssertion( "stimulation of leukocyte activation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002696") -AnnotationAssertion(rdfs:label "positive regulation of leukocyte activation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of immune effector process) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that modulates the frequency, rate, or extent of an immune effector process.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002697") -AnnotationAssertion(rdfs:label "regulation of immune effector process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (negative regulation of immune effector process) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune effector process.") -AnnotationAssertion( "down regulation of immune effector process") -AnnotationAssertion( "down-regulation of immune effector process") -AnnotationAssertion( "downregulation of immune effector process") -AnnotationAssertion( "inhibition of immune effector process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002698") -AnnotationAssertion(rdfs:label "negative regulation of immune effector process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of immune effector process) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that activates or increases the frequency, rate, or extent of an immune effector process.") -AnnotationAssertion( "up regulation of immune effector process") -AnnotationAssertion( "up-regulation of immune effector process") -AnnotationAssertion( "upregulation of immune effector process") -AnnotationAssertion( "activation of immune effector process") -AnnotationAssertion( "stimulation of immune effector process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002699") -AnnotationAssertion(rdfs:label "positive regulation of immune effector process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of production of molecular mediator of immune response) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that modulates the frequency, rate, or extent of the production of molecular mediator of immune response.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002700") -AnnotationAssertion(rdfs:label "regulation of production of molecular mediator of immune response") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (negative regulation of production of molecular mediator of immune response) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that stops, prevents, or reduces the frequency, rate, or extent of the production of molecular mediator of immune response.") -AnnotationAssertion( "down regulation of production of molecular mediator of immune response") -AnnotationAssertion( "down-regulation of production of molecular mediator of immune response") -AnnotationAssertion( "downregulation of production of molecular mediator of immune response") -AnnotationAssertion( "inhibition of production of molecular mediator of immune response") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002701") -AnnotationAssertion(rdfs:label "negative regulation of production of molecular mediator of immune response") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of production of molecular mediator of immune response) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that activates or increases the frequency, rate, or extent of the production of molecular mediator of immune response.") -AnnotationAssertion( "up regulation of production of molecular mediator of immune response") -AnnotationAssertion( "up-regulation of production of molecular mediator of immune response") -AnnotationAssertion( "upregulation of production of molecular mediator of immune response") -AnnotationAssertion( "activation of production of molecular mediator of immune response") -AnnotationAssertion( "stimulation of production of molecular mediator of immune response") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002702") -AnnotationAssertion(rdfs:label "positive regulation of production of molecular mediator of immune response") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of leukocyte mediated immunity) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that modulates the frequency, rate, or extent of leukocyte mediated immunity.") -AnnotationAssertion( "regulation of immune cell mediated immunity") -AnnotationAssertion( "regulation of leucocyte mediated immunity") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002703") -AnnotationAssertion(rdfs:label "regulation of leukocyte mediated immunity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of leukocyte mediated immunity) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte mediated immunity.") -AnnotationAssertion( "down regulation of leukocyte mediated immunity") -AnnotationAssertion( "down-regulation of leukocyte mediated immunity") -AnnotationAssertion( "downregulation of leukocyte mediated immunity") -AnnotationAssertion( "negative regulation of immune cell mediated immunity") -AnnotationAssertion( "negative regulation of leucocyte mediated immunity") -AnnotationAssertion( "inhibition of leukocyte mediated immunity") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002704") -AnnotationAssertion(rdfs:label "negative regulation of leukocyte mediated immunity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of leukocyte mediated immunity) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that activates or increases the frequency, rate, or extent of leukocyte mediated immunity.") -AnnotationAssertion( "positive regulation of immune cell mediated immunity") -AnnotationAssertion( "positive regulation of leucocyte mediated immunity") -AnnotationAssertion( "up regulation of leukocyte mediated immunity") -AnnotationAssertion( "up-regulation of leukocyte mediated immunity") -AnnotationAssertion( "upregulation of leukocyte mediated immunity") -AnnotationAssertion( "activation of leukocyte mediated immunity") -AnnotationAssertion( "stimulation of leukocyte mediated immunity") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002705") -AnnotationAssertion(rdfs:label "positive regulation of leukocyte mediated immunity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of lymphocyte mediated immunity) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that modulates the frequency, rate, or extent of lymphocyte mediated immunity.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002706") -AnnotationAssertion(rdfs:label "regulation of lymphocyte mediated immunity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of lymphocyte mediated immunity) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that stops, prevents, or reduces the frequency, rate, or extent of lymphocyte mediated immunity.") -AnnotationAssertion( "down regulation of lymphocyte mediated immunity") -AnnotationAssertion( "down-regulation of lymphocyte mediated immunity") -AnnotationAssertion( "downregulation of lymphocyte mediated immunity") -AnnotationAssertion( "inhibition of lymphocyte mediated immunity") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002707") -AnnotationAssertion(rdfs:label "negative regulation of lymphocyte mediated immunity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of lymphocyte mediated immunity) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that activates or increases the frequency, rate, or extent of lymphocyte mediated immunity.") -AnnotationAssertion( "up regulation of lymphocyte mediated immunity") -AnnotationAssertion( "up-regulation of lymphocyte mediated immunity") -AnnotationAssertion( "upregulation of lymphocyte mediated immunity") -AnnotationAssertion( "activation of lymphocyte mediated immunity") -AnnotationAssertion( "stimulation of lymphocyte mediated immunity") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002708") -AnnotationAssertion(rdfs:label "positive regulation of lymphocyte mediated immunity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of T cell mediated immunity) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that modulates the frequency, rate, or extent of T cell mediated immunity.") -AnnotationAssertion( "regulation of T lymphocyte mediated immunity") -AnnotationAssertion( "regulation of T-cell mediated immunity") -AnnotationAssertion( "regulation of T-lymphocyte mediated immunity") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002709") -AnnotationAssertion(rdfs:label "regulation of T cell mediated immunity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of T cell mediated immunity) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell mediated immunity.") -AnnotationAssertion( "down regulation of T cell mediated immunity") -AnnotationAssertion( "down-regulation of T cell mediated immunity") -AnnotationAssertion( "downregulation of T cell mediated immunity") -AnnotationAssertion( "negative regulation of T lymphocyte mediated immunity") -AnnotationAssertion( "negative regulation of T-cell mediated immunity") -AnnotationAssertion( "negative regulation of T-lymphocyte mediated immunity") -AnnotationAssertion( "inhibition of T cell mediated immunity") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002710") -AnnotationAssertion(rdfs:label "negative regulation of T cell mediated immunity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of T cell mediated immunity) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that activates or increases the frequency, rate, or extent of T cell mediated immunity.") -AnnotationAssertion( "positive regulation of T lymphocyte mediated immunity") -AnnotationAssertion( "positive regulation of T-cell mediated immunity") -AnnotationAssertion( "positive regulation of T-lymphocyte mediated immunity") -AnnotationAssertion( "up regulation of T cell mediated immunity") -AnnotationAssertion( "up-regulation of T cell mediated immunity") -AnnotationAssertion( "upregulation of T cell mediated immunity") -AnnotationAssertion( "activation of T cell mediated immunity") -AnnotationAssertion( "stimulation of T cell mediated immunity") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002711") -AnnotationAssertion(rdfs:label "positive regulation of T cell mediated immunity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of B cell mediated immunity) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that modulates the frequency, rate, or extent of B cell mediated immunity.") -AnnotationAssertion( "regulation of B lymphocyte mediated immunity") -AnnotationAssertion( "regulation of B-cell mediated immunity") -AnnotationAssertion( "regulation of B-lymphocyte mediated immunity") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002712") -AnnotationAssertion(rdfs:label "regulation of B cell mediated immunity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of B cell mediated immunity) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell mediated immunity.") -AnnotationAssertion( "down regulation of B cell mediated immunity") -AnnotationAssertion( "down-regulation of B cell mediated immunity") -AnnotationAssertion( "downregulation of B cell mediated immunity") -AnnotationAssertion( "negative regulation of B lymphocyte mediated immunity") -AnnotationAssertion( "negative regulation of B-cell mediated immunity") -AnnotationAssertion( "negative regulation of B-lymphocyte mediated immunity") -AnnotationAssertion( "inhibition of B cell mediated immunity") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002713") -AnnotationAssertion(rdfs:label "negative regulation of B cell mediated immunity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of B cell mediated immunity) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that activates or increases the frequency, rate, or extent of B cell mediated immunity.") -AnnotationAssertion( "positive regulation of B lymphocyte mediated immunity") -AnnotationAssertion( "positive regulation of B-cell mediated immunity") -AnnotationAssertion( "positive regulation of B-lymphocyte mediated immunity") -AnnotationAssertion( "up regulation of B cell mediated immunity") -AnnotationAssertion( "up-regulation of B cell mediated immunity") -AnnotationAssertion( "upregulation of B cell mediated immunity") -AnnotationAssertion( "activation of B cell mediated immunity") -AnnotationAssertion( "stimulation of B cell mediated immunity") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002714") -AnnotationAssertion(rdfs:label "positive regulation of B cell mediated immunity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of cytokine production involved in immune response) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that modulates the frequency, rate, or extent of cytokine production that contributes to an immune response.") -AnnotationAssertion( "GO:0002739") -AnnotationAssertion( "GO:0002742") -AnnotationAssertion( "regulation of cytokine biosynthetic process involved in immune response") -AnnotationAssertion( "regulation of cytokine secretion involved in immune response") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") "regulation of cytokine production during immune response") -AnnotationAssertion( "GO:0002718") -AnnotationAssertion(rdfs:label "regulation of cytokine production involved in immune response") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of cytokine production involved in immune response) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that stops, prevents, or reduces the frequency, rate, or extent of cytokine production contributing to an immune response.") -AnnotationAssertion( "GO:0002740") -AnnotationAssertion( "GO:0002743") -AnnotationAssertion( "down-regulation of cytokine production during immune response") -AnnotationAssertion( "negative regulation of cytokine biosynthetic process involved in immune response") -AnnotationAssertion( "negative regulation of cytokine secretion involved in immune response") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "down regulation of cytokine production during immune response") -AnnotationAssertion( "downregulation of cytokine production during immune response") -AnnotationAssertion( "inhibition of cytokine production during immune response") -AnnotationAssertion(Annotation( "GOC:dph") "negative regulation of cytokine production during immune response") -AnnotationAssertion( "GO:0002719") -AnnotationAssertion(rdfs:label "negative regulation of cytokine production involved in immune response") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of cytokine production involved in immune response) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that activates or increases the frequency, rate, or extent of cytokine production that contributes to an immune response.") -AnnotationAssertion( "GO:0002741") -AnnotationAssertion( "GO:0002744") -AnnotationAssertion( "activation of cytokine production during immune response") -AnnotationAssertion( "positive regulation of cytokine biosynthetic process involved in immune response") -AnnotationAssertion( "positive regulation of cytokine secretion involved in immune response") -AnnotationAssertion( "stimulation of cytokine production during immune response") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") "positive regulation of cytokine production during immune response") -AnnotationAssertion( "up regulation of cytokine production during immune response") -AnnotationAssertion( "up-regulation of cytokine production during immune response") -AnnotationAssertion( "upregulation of cytokine production during immune response") -AnnotationAssertion( "GO:0002720") -AnnotationAssertion(rdfs:label "positive regulation of cytokine production involved in immune response") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of B cell cytokine production) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that modulates the frequency, rate, or extent of B cell cytokine production.") -AnnotationAssertion( "regulation of B lymphocyte cytokine production") -AnnotationAssertion( "regulation of B-cell cytokine production") -AnnotationAssertion( "regulation of B-lymphocyte cytokine production") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002721") -AnnotationAssertion(rdfs:label "regulation of B cell cytokine production") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of B cell cytokine production) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell cytokine production.") -AnnotationAssertion( "down regulation of B cell cytokine production") -AnnotationAssertion( "down-regulation of B cell cytokine production") -AnnotationAssertion( "downregulation of B cell cytokine production") -AnnotationAssertion( "negative regulation of B lymphocyte cytokine production") -AnnotationAssertion( "negative regulation of B-cell cytokine production") -AnnotationAssertion( "negative regulation of B-lymphocyte cytokine production") -AnnotationAssertion( "inhibition of B cell cytokine production") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002722") -AnnotationAssertion(rdfs:label "negative regulation of B cell cytokine production") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of B cell cytokine production) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that activates or increases the frequency, rate, or extent of B cell cytokine production.") -AnnotationAssertion( "positive regulation of B lymphocyte cytokine production") -AnnotationAssertion( "positive regulation of B-cell cytokine production") -AnnotationAssertion( "positive regulation of B-lymphocyte cytokine production") -AnnotationAssertion( "up regulation of B cell cytokine production") -AnnotationAssertion( "up-regulation of B cell cytokine production") -AnnotationAssertion( "upregulation of B cell cytokine production") -AnnotationAssertion( "activation of B cell cytokine production") -AnnotationAssertion( "stimulation of B cell cytokine production") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002723") -AnnotationAssertion(rdfs:label "positive regulation of B cell cytokine production") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of T cell cytokine production) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that modulates the frequency, rate, or extent of T cell cytokine production.") -AnnotationAssertion( "regulation of T lymphocyte cytokine production") -AnnotationAssertion( "regulation of T-cell cytokine production") -AnnotationAssertion( "regulation of T-lymphocyte cytokine production") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002724") -AnnotationAssertion(rdfs:label "regulation of T cell cytokine production") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of T cell cytokine production) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell cytokine production.") -AnnotationAssertion( "down regulation of T cell cytokine production") -AnnotationAssertion( "down-regulation of T cell cytokine production") -AnnotationAssertion( "downregulation of T cell cytokine production") -AnnotationAssertion( "negative regulation of T lymphocyte cytokine production") -AnnotationAssertion( "negative regulation of T-cell cytokine production") -AnnotationAssertion( "negative regulation of T-lymphocyte cytokine production") -AnnotationAssertion( "inhibition of T cell cytokine production") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002725") -AnnotationAssertion(rdfs:label "negative regulation of T cell cytokine production") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of T cell cytokine production) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that activates or increases the frequency, rate, or extent of T cell cytokine production.") -AnnotationAssertion( "positive regulation of T lymphocyte cytokine production") -AnnotationAssertion( "positive regulation of T-cell cytokine production") -AnnotationAssertion( "positive regulation of T-lymphocyte cytokine production") -AnnotationAssertion( "up regulation of T cell cytokine production") -AnnotationAssertion( "up-regulation of T cell cytokine production") -AnnotationAssertion( "upregulation of T cell cytokine production") -AnnotationAssertion( "activation of T cell cytokine production") -AnnotationAssertion( "stimulation of T cell cytokine production") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002726") -AnnotationAssertion(rdfs:label "positive regulation of T cell cytokine production") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of dendritic cell cytokine production) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that modulates the frequency, rate, or extent of dendritic cell cytokine production.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002730") -AnnotationAssertion(rdfs:label "regulation of dendritic cell cytokine production") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of dendritic cell cytokine production) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that stops, prevents, or reduces the frequency, rate, or extent of dendritic cell cytokine production.") -AnnotationAssertion( "down regulation of dendritic cell cytokine production") -AnnotationAssertion( "down-regulation of dendritic cell cytokine production") -AnnotationAssertion( "downregulation of dendritic cell cytokine production") -AnnotationAssertion( "inhibition of dendritic cell cytokine production") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002731") -AnnotationAssertion(rdfs:label "negative regulation of dendritic cell cytokine production") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of dendritic cell cytokine production) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that activates or increases the frequency, rate, or extent of dendritic cell cytokine production.") -AnnotationAssertion( "up regulation of dendritic cell cytokine production") -AnnotationAssertion( "up-regulation of dendritic cell cytokine production") -AnnotationAssertion( "upregulation of dendritic cell cytokine production") -AnnotationAssertion( "activation of dendritic cell cytokine production") -AnnotationAssertion( "stimulation of dendritic cell cytokine production") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002732") -AnnotationAssertion(rdfs:label "positive regulation of dendritic cell cytokine production") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of myeloid dendritic cell cytokine production) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that modulates the frequency, rate, or extent of myeloid dendritic cell cytokine production.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002733") -AnnotationAssertion(rdfs:label "regulation of myeloid dendritic cell cytokine production") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of myeloid dendritic cell cytokine production) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid dendritic cell cytokine production.") -AnnotationAssertion( "down regulation of myeloid dendritic cell cytokine production") -AnnotationAssertion( "down-regulation of myeloid dendritic cell cytokine production") -AnnotationAssertion( "downregulation of myeloid dendritic cell cytokine production") -AnnotationAssertion( "inhibition of myeloid dendritic cell cytokine production") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002734") -AnnotationAssertion(rdfs:label "negative regulation of myeloid dendritic cell cytokine production") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of myeloid dendritic cell cytokine production) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that activates or increases the frequency, rate, or extent of myeloid dendritic cell cytokine production.") -AnnotationAssertion( "up regulation of myeloid dendritic cell cytokine production") -AnnotationAssertion( "up-regulation of myeloid dendritic cell cytokine production") -AnnotationAssertion( "upregulation of myeloid dendritic cell cytokine production") -AnnotationAssertion( "activation of myeloid dendritic cell cytokine production") -AnnotationAssertion( "stimulation of myeloid dendritic cell cytokine production") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002735") -AnnotationAssertion(rdfs:label "positive regulation of myeloid dendritic cell cytokine production") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of antimicrobial humoral response) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that modulates the frequency, rate, or extent of an antimicrobial humoral response.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002759") -AnnotationAssertion(rdfs:label "regulation of antimicrobial humoral response") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of antimicrobial humoral response) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that activates or increases the frequency, rate, or extent of an antimicrobial humoral response.") -AnnotationAssertion( "up regulation of antimicrobial humoral response") -AnnotationAssertion( "up-regulation of antimicrobial humoral response") -AnnotationAssertion( "upregulation of antimicrobial humoral response") -AnnotationAssertion( "activation of antimicrobial humoral response") -AnnotationAssertion( "stimulation of antimicrobial humoral response") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002760") -AnnotationAssertion(rdfs:label "positive regulation of antimicrobial humoral response") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of myeloid leukocyte differentiation) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that modulates the frequency, rate, or extent of myeloid leukocyte differentiation.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002761") -AnnotationAssertion(rdfs:label "regulation of myeloid leukocyte differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of myeloid leukocyte differentiation) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid leukocyte differentiation.") -AnnotationAssertion( "down regulation of myeloid leukocyte differentiation") -AnnotationAssertion( "down-regulation of myeloid leukocyte differentiation") -AnnotationAssertion( "downregulation of myeloid leukocyte differentiation") -AnnotationAssertion( "inhibition of myeloid leukocyte differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002762") -AnnotationAssertion(rdfs:label "negative regulation of myeloid leukocyte differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of myeloid leukocyte differentiation) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that activates or increases the frequency, rate, or extent of myeloid leukocyte differentiation.") -AnnotationAssertion( "up regulation of myeloid leukocyte differentiation") -AnnotationAssertion( "up-regulation of myeloid leukocyte differentiation") -AnnotationAssertion( "upregulation of myeloid leukocyte differentiation") -AnnotationAssertion( "activation of myeloid leukocyte differentiation") -AnnotationAssertion( "stimulation of myeloid leukocyte differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002763") -AnnotationAssertion(rdfs:label "positive regulation of myeloid leukocyte differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (antimicrobial peptide production) AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") Annotation( "PMID:11807545") Annotation( "PMID:15638771") "The synthesis or release of an antimicrobial peptide during an immune response, resulting in an increase in intracellular or extracellular levels. Such peptides may have protective properties against bacteria, fungi, viruses, or protozoa.") @@ -49681,497 +20411,15 @@ AnnotationAssertion(rdfs:label "anti SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (regulation of antimicrobial peptide production) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that modulates the frequency, rate, or extent of antimicrobial peptide production.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002784") -AnnotationAssertion(rdfs:label "regulation of antimicrobial peptide production") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (negative regulation of antimicrobial peptide production) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that stops, prevents, or reduces the frequency, rate, or extent of antimicrobial peptide production.") -AnnotationAssertion( "down regulation of antimicrobial peptide production") -AnnotationAssertion( "down-regulation of antimicrobial peptide production") -AnnotationAssertion( "downregulation of antimicrobial peptide production") -AnnotationAssertion( "inhibition of antimicrobial peptide production") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002785") -AnnotationAssertion(rdfs:label "negative regulation of antimicrobial peptide production") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - # Class: (peptide secretion) AnnotationAssertion(Annotation( "GOC:add") "The controlled release of a peptide from a cell or a tissue.") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0002790") AnnotationAssertion(rdfs:label "peptide secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) -# Class: (regulation of peptide secretion) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that modulates the frequency, rate, or extent of peptide secretion.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002791") -AnnotationAssertion(rdfs:label "regulation of peptide secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of peptide secretion) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that stops, prevents, or reduces the frequency, rate, or extent of peptide secretion.") -AnnotationAssertion( "down regulation of peptide secretion") -AnnotationAssertion( "down-regulation of peptide secretion") -AnnotationAssertion( "downregulation of peptide secretion") -AnnotationAssertion( "inhibition of peptide secretion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002792") -AnnotationAssertion(rdfs:label "negative regulation of peptide secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of peptide secretion) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that activates or increases the frequency, rate, or extent of peptide secretion.") -AnnotationAssertion( "up regulation of peptide secretion") -AnnotationAssertion( "up-regulation of peptide secretion") -AnnotationAssertion( "upregulation of peptide secretion") -AnnotationAssertion( "activation of peptide secretion") -AnnotationAssertion( "stimulation of peptide secretion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002793") -AnnotationAssertion(rdfs:label "positive regulation of peptide secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of antimicrobial peptide secretion) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that modulates the frequency, rate, or extent of antimicrobial peptide secretion.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002794") -AnnotationAssertion(rdfs:label "regulation of antimicrobial peptide secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (negative regulation of antimicrobial peptide secretion) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that stops, prevents, or reduces the frequency, rate, or extent of antimicrobial peptide secretion.") -AnnotationAssertion( "down regulation of antimicrobial peptide secretion") -AnnotationAssertion( "down-regulation of antimicrobial peptide secretion") -AnnotationAssertion( "downregulation of antimicrobial peptide secretion") -AnnotationAssertion( "inhibition of antimicrobial peptide secretion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002795") -AnnotationAssertion(rdfs:label "negative regulation of antimicrobial peptide secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of antimicrobial peptide secretion) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that activates or increases the frequency, rate, or extent of antimicrobial peptide secretion.") -AnnotationAssertion( "up regulation of antimicrobial peptide secretion") -AnnotationAssertion( "up-regulation of antimicrobial peptide secretion") -AnnotationAssertion( "upregulation of antimicrobial peptide secretion") -AnnotationAssertion( "activation of antimicrobial peptide secretion") -AnnotationAssertion( "stimulation of antimicrobial peptide secretion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002796") -AnnotationAssertion(rdfs:label "positive regulation of antimicrobial peptide secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (regulation of adaptive immune response) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that modulates the frequency, rate, or extent of an adaptive immune response.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002819") -AnnotationAssertion(rdfs:label "regulation of adaptive immune response") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of adaptive immune response) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that stops, prevents, or reduces the frequency, rate, or extent of an adaptive immune response.") -AnnotationAssertion( "down regulation of adaptive immune response") -AnnotationAssertion( "down-regulation of adaptive immune response") -AnnotationAssertion( "downregulation of adaptive immune response") -AnnotationAssertion( "inhibition of adaptive immune response") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002820") -AnnotationAssertion(rdfs:label "negative regulation of adaptive immune response") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of adaptive immune response) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that activates or increases the frequency, rate, or extent of an adaptive immune response.") -AnnotationAssertion( "up regulation of adaptive immune response") -AnnotationAssertion( "up-regulation of adaptive immune response") -AnnotationAssertion( "upregulation of adaptive immune response") -AnnotationAssertion( "activation of adaptive immune response") -AnnotationAssertion( "stimulation of adaptive immune response") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002821") -AnnotationAssertion(rdfs:label "positive regulation of adaptive immune response") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:mtg_sensu") "Any process that modulates the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002822") -AnnotationAssertion(rdfs:label "regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - -# Class: (negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:mtg_sensu") "Any process that stops, prevents, or reduces the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002823") -AnnotationAssertion(rdfs:label "negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:mtg_sensu") "Any process that activates or increases the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002824") -AnnotationAssertion(rdfs:label "positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of type 2 immune response) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that modulates the frequency, rate, or extent of a type 2 immune response.") -AnnotationAssertion(Annotation( "GOC:add") "regulation of T-helper 2 type immune response") -AnnotationAssertion(Annotation( "GOC:add") "regulation of Th2 immune response") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002828") -AnnotationAssertion(rdfs:label "regulation of type 2 immune response") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of type 2 immune response) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that stops, prevents, or reduces the frequency, rate, or extent of a type 2 immune response.") -AnnotationAssertion( "down regulation of type 2 immune response") -AnnotationAssertion( "down-regulation of type 2 immune response") -AnnotationAssertion( "downregulation of type 2 immune response") -AnnotationAssertion( "inhibition of type 2 immune response") -AnnotationAssertion(Annotation( "GOC:add") "negative regulation of T-helper 2 type immune response") -AnnotationAssertion(Annotation( "GOC:add") "negative regulation of Th2 immune response") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002829") -AnnotationAssertion(rdfs:label "negative regulation of type 2 immune response") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of type 2 immune response) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that activates or increases the frequency, rate, or extent of a type 2 immune response.") -AnnotationAssertion( "up regulation of type 2 immune response") -AnnotationAssertion( "up-regulation of type 2 immune response") -AnnotationAssertion( "upregulation of type 2 immune response") -AnnotationAssertion( "activation of type 2 immune response") -AnnotationAssertion(Annotation( "GOC:add") "positive regulation of T-helper 2 type immune response") -AnnotationAssertion(Annotation( "GOC:add") "positive regulation of Th2 immune response") -AnnotationAssertion( "stimulation of type 2 immune response") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002830") -AnnotationAssertion(rdfs:label "positive regulation of type 2 immune response") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of response to biotic stimulus) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that modulates the frequency, rate, or extent of a response to biotic stimulus.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002831") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.") -AnnotationAssertion(rdfs:label "regulation of response to biotic stimulus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of response to biotic stimulus) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that stops, prevents, or reduces the frequency, rate, or extent of a response to biotic stimulus.") -AnnotationAssertion( "down regulation of response to biotic stimulus") -AnnotationAssertion( "down-regulation of response to biotic stimulus") -AnnotationAssertion( "downregulation of response to biotic stimulus") -AnnotationAssertion( "inhibition of response to biotic stimulus") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002832") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.") -AnnotationAssertion(rdfs:label "negative regulation of response to biotic stimulus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of response to biotic stimulus) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that activates or increases the frequency, rate, or extent of a response to biotic stimulus.") -AnnotationAssertion( "up regulation of response to biotic stimulus") -AnnotationAssertion( "up-regulation of response to biotic stimulus") -AnnotationAssertion( "upregulation of response to biotic stimulus") -AnnotationAssertion( "activation of response to biotic stimulus") -AnnotationAssertion( "stimulation of response to biotic stimulus") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002833") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.") -AnnotationAssertion(rdfs:label "positive regulation of response to biotic stimulus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of myeloid leukocyte mediated immunity) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that modulates the frequency, rate, or extent of myeloid leukocyte mediated immunity.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002886") -AnnotationAssertion(rdfs:label "regulation of myeloid leukocyte mediated immunity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of myeloid leukocyte mediated immunity) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid leukocyte mediated immunity.") -AnnotationAssertion( "down regulation of myeloid leukocyte mediated immunity") -AnnotationAssertion( "down-regulation of myeloid leukocyte mediated immunity") -AnnotationAssertion( "downregulation of myeloid leukocyte mediated immunity") -AnnotationAssertion( "inhibition of myeloid leukocyte mediated immunity") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002887") -AnnotationAssertion(rdfs:label "negative regulation of myeloid leukocyte mediated immunity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of myeloid leukocyte mediated immunity) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that activates or increases the frequency, rate, or extent of myeloid leukocyte mediated immunity.") -AnnotationAssertion( "up regulation of myeloid leukocyte mediated immunity") -AnnotationAssertion( "up-regulation of myeloid leukocyte mediated immunity") -AnnotationAssertion( "upregulation of myeloid leukocyte mediated immunity") -AnnotationAssertion( "activation of myeloid leukocyte mediated immunity") -AnnotationAssertion( "stimulation of myeloid leukocyte mediated immunity") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002888") -AnnotationAssertion(rdfs:label "positive regulation of myeloid leukocyte mediated immunity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of immunoglobulin mediated immune response) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that modulates the frequency, rate, or extent of an immunoglobulin mediated immune response.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002889") -AnnotationAssertion(rdfs:label "regulation of immunoglobulin mediated immune response") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of immunoglobulin mediated immune response) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that stops, prevents, or reduces the frequency, rate, or extent of an immunoglobulin mediated immune response.") -AnnotationAssertion( "down regulation of immunoglobulin mediated immune response") -AnnotationAssertion( "down-regulation of immunoglobulin mediated immune response") -AnnotationAssertion( "downregulation of immunoglobulin mediated immune response") -AnnotationAssertion( "inhibition of immunoglobulin mediated immune response") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002890") -AnnotationAssertion(rdfs:label "negative regulation of immunoglobulin mediated immune response") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of immunoglobulin mediated immune response) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that activates or increases the frequency, rate, or extent of an immunoglobulin mediated immune response.") -AnnotationAssertion( "up regulation of immunoglobulin mediated immune response") -AnnotationAssertion( "up-regulation of immunoglobulin mediated immune response") -AnnotationAssertion( "upregulation of immunoglobulin mediated immune response") -AnnotationAssertion( "activation of immunoglobulin mediated immune response") -AnnotationAssertion( "stimulation of immunoglobulin mediated immune response") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002891") -AnnotationAssertion(rdfs:label "positive regulation of immunoglobulin mediated immune response") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (mature B cell apoptotic process) - -AnnotationAssertion(Annotation( "CL:0000785") Annotation( "GOC:add") Annotation( "GOC:mtg_apoptosis") Annotation( "ISBN:0781735149") "Any apoptotic process in a B cell that is mature, having left the bone marrow.") -AnnotationAssertion( "apoptosis of mature B cells") -AnnotationAssertion( "apoptosis of mature B lymphocytes") -AnnotationAssertion( "apoptosis of mature B-cells") -AnnotationAssertion( "apoptosis of mature B-lymphocytes") -AnnotationAssertion( "mature B cell programmed cell death by apoptosis") -AnnotationAssertion( "mature B lymphocyte apoptosis") -AnnotationAssertion( "mature B lymphocyte programmed cell death by apoptosis") -AnnotationAssertion( "mature B-cell apoptosis") -AnnotationAssertion( "mature B-cell programmed cell death by apoptosis") -AnnotationAssertion( "mature B-lymphocyte apoptosis") -AnnotationAssertion( "mature B-lymphocyte programmed cell death by apoptosis") -AnnotationAssertion( "programmed cell death of mature B cells by apoptosis") -AnnotationAssertion( "programmed cell death of mature B lymphocytes by apoptosis") -AnnotationAssertion( "programmed cell death of mature B-cells by apoptosis") -AnnotationAssertion( "programmed cell death of mature B-lymphocytes by apoptosis") -AnnotationAssertion( "programmed cell death, mature B cells") -AnnotationAssertion( "programmed cell death, mature B lymphocytes") -AnnotationAssertion( "programmed cell death, mature B-cells") -AnnotationAssertion( "programmed cell death, mature B-lymphocytes") -AnnotationAssertion( "mature B cell apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002901") -AnnotationAssertion(rdfs:label "mature B cell apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (regulation of B cell apoptotic process) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:mtg_apoptosis") "Any process that modulates the frequency, rate, or extent of B cell apoptotic process.") -AnnotationAssertion( "regulation of B cell apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002902") -AnnotationAssertion(rdfs:label "regulation of B cell apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of B cell apoptotic process) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:mtg_apoptosis") "Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell apoptotic process.") -AnnotationAssertion( "down regulation of B cell apoptosis") -AnnotationAssertion( "down-regulation of B cell apoptosis") -AnnotationAssertion( "downregulation of B cell apoptosis") -AnnotationAssertion( "inhibition of B cell apoptosis") -AnnotationAssertion( "negative regulation of B cell apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002903") -AnnotationAssertion(rdfs:label "negative regulation of B cell apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of B cell apoptotic process) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:mtg_apoptosis") "Any process that activates or increases the frequency, rate, or extent of B cell apoptotic process.") -AnnotationAssertion( "up regulation of B cell apoptosis") -AnnotationAssertion( "up-regulation of B cell apoptosis") -AnnotationAssertion( "upregulation of B cell apoptosis") -AnnotationAssertion( "activation of B cell apoptosis") -AnnotationAssertion( "positive regulation of B cell apoptosis") -AnnotationAssertion( "stimulation of B cell apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002904") -AnnotationAssertion(rdfs:label "positive regulation of B cell apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of mature B cell apoptotic process) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:mtg_apoptosis") "Any process that modulates the frequency, rate, or extent of mature B cell apoptotic process.") -AnnotationAssertion( "regulation of mature B cell apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002905") -AnnotationAssertion(rdfs:label "regulation of mature B cell apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (negative regulation of mature B cell apoptotic process) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:mtg_apoptosis") "Any process that stops, prevents, or reduces the frequency, rate, or extent of mature B cell apoptotic process.") -AnnotationAssertion( "down regulation of mature B cell apoptosis") -AnnotationAssertion( "down-regulation of mature B cell apoptosis") -AnnotationAssertion( "downregulation of mature B cell apoptosis") -AnnotationAssertion( "inhibition of mature B cell apoptosis") -AnnotationAssertion( "negative regulation of mature B cell apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002906") -AnnotationAssertion(rdfs:label "negative regulation of mature B cell apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of mature B cell apoptotic process) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:mtg_apoptosis") "Any process that activates or increases the frequency, rate, or extent of mature B cell apoptotic process.") -AnnotationAssertion( "up regulation of mature B cell apoptosis") -AnnotationAssertion( "up-regulation of mature B cell apoptosis") -AnnotationAssertion( "upregulation of mature B cell apoptosis") -AnnotationAssertion( "activation of mature B cell apoptosis") -AnnotationAssertion( "positive regulation of mature B cell apoptosis") -AnnotationAssertion( "stimulation of mature B cell apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002907") -AnnotationAssertion(rdfs:label "positive regulation of mature B cell apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (regulation of humoral immune response) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that modulates the frequency, rate, or extent of a humoral immune response.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002920") -AnnotationAssertion(rdfs:label "regulation of humoral immune response") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of humoral immune response) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that stops, prevents, or reduces the frequency, rate, or extent of a humoral immune response.") -AnnotationAssertion( "down regulation of humoral immune response") -AnnotationAssertion( "down-regulation of humoral immune response") -AnnotationAssertion( "downregulation of humoral immune response") -AnnotationAssertion( "inhibition of humoral immune response") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002921") -AnnotationAssertion(rdfs:label "negative regulation of humoral immune response") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of humoral immune response) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that activates or increases the frequency, rate, or extent of a humoral immune response.") -AnnotationAssertion( "up regulation of humoral immune response") -AnnotationAssertion( "up-regulation of humoral immune response") -AnnotationAssertion( "upregulation of humoral immune response") -AnnotationAssertion( "activation of humoral immune response") -AnnotationAssertion( "stimulation of humoral immune response") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002922") -AnnotationAssertion(rdfs:label "positive regulation of humoral immune response") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (trabecular meshwork development) - -AnnotationAssertion(Annotation( "PMID:20568247") "The progression of the trabecular meshwork over time, from its formation to the mature structure. The trabecular meshwork is a fenestrated endothelial-like tissue situated at the intersection of the cornea and the iris. The trabecular meshwork provides drainage for the aqueous humor.") -AnnotationAssertion( "hjd") -AnnotationAssertion( "2012-04-19T04:50:06Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002930") -AnnotationAssertion(rdfs:label "trabecular meshwork development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (tendon sheath development) - -AnnotationAssertion(Annotation( "PMID:20696843") "The process whose specific outcome is the progression of a tendon sheath over time, from its formation to the mature structure. A tendon sheath is a layer of membrane around a tendon. It permits the tendon to move.") -AnnotationAssertion( "hjd") -AnnotationAssertion( "2012-04-23T02:11:22Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002932") -AnnotationAssertion(rdfs:label "tendon sheath development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (synoviocyte proliferation) - -AnnotationAssertion(Annotation( "PMID:10770586") Annotation( "PMID:9546370") "The multiplication or reproduction of type B synoviocytes by cell division, resulting in the expansion of their population. A type B synoviocyte is a fibroblast-like cell found in synovial tissues.") -AnnotationAssertion( "hjd") -AnnotationAssertion( "2012-11-16T14:25:45Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0002941") -AnnotationAssertion(rdfs:label "synoviocyte proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regionalization) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:isa_complete") "The pattern specification process that results in the subdivision of an axis or axes in space to define an area or volume in which specific patterns of cell differentiation will take place or in which cells interpret a specific environment.") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") "pattern formation") -AnnotationAssertion( "GO:0003002") -AnnotationAssertion(rdfs:label "regionalization") -SubClassOf( ) - # Class: (developmental process involved in reproduction) AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:isa_complete") "A developmental process in which a progressive change in the state of some part of an organism, germline or somatic, specifically contributes to its ability to form offspring.") @@ -50180,21 +20428,9 @@ AnnotationAssertion( "GOC:dph") Annotation( "GOC:tb") "reproductive developmental process") AnnotationAssertion( "GO:0003006") AnnotationAssertion(rdfs:label "developmental process involved in reproduction") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) -# Class: (heart morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:isa_complete") "The developmental process in which the heart is generated and organized. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "cardiac morphogenesis") -AnnotationAssertion( "GO:0003007") -AnnotationAssertion(rdfs:label "heart morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (system process) AnnotationAssertion(Annotation( "GOC:mtg_cardio") "A multicellular organismal process carried out by any of the organs or tissues in an organ system. An organ system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a biological objective.") @@ -50204,16 +20440,6 @@ AnnotationAssertion( "system process") SubClassOf( ) -# Class: (skeletal muscle contraction) - -AnnotationAssertion(Annotation( "GOC:mtg_cardio") Annotation( "GOC:mtg_muscle") "A process in which force is generated within skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. In the skeletal muscle, the muscle contraction takes advantage of an ordered sarcomeric structure and in most cases it is under voluntary control.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003009") -AnnotationAssertion(rdfs:label "skeletal muscle contraction") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (muscle system process) AnnotationAssertion(Annotation( "GOC:mtg_cardio") "A organ system process carried out at the level of a muscle. Muscle tissue is composed of contractile cells or fibers.") @@ -50276,15 +20502,6 @@ AnnotationAssertion( "lymph circulation") SubClassOf( ) -# Class: (vascular process in circulatory system) - -AnnotationAssertion(Annotation( "GOC:mtg_cardio") "A circulatory process that occurs at the level of the vasculature.") -AnnotationAssertion( "vasculature process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003018") -AnnotationAssertion(rdfs:label "vascular process in circulatory system") -SubClassOf( ) - # Class: (central nervous system control of baroreceptor feedback) AnnotationAssertion(Annotation( "GOC:mtg_cardio") Annotation( "ISBN:0323031951") "The neurological process in which nerve impulses arising in the aorta or the carotid sinuses travel to the medulla and reach the nucleus of tractus solaris.") @@ -50388,7 +20605,6 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:0003071") AnnotationAssertion(rdfs:label "renal system process involved in regulation of systemic arterial blood pressure") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) # Class: (regulation of systemic arterial blood pressure) @@ -50424,7 +20640,6 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:0003093") AnnotationAssertion(rdfs:label "regulation of glomerular filtration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) @@ -50434,2193 +20649,19 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:0003094") AnnotationAssertion(rdfs:label "glomerular filtration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (renal sodium ion transport) - -AnnotationAssertion(Annotation( "GOC:mtg_cardio") "The directed movement of sodium ions (Na+) by the renal system.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003096") -AnnotationAssertion(rdfs:label "renal sodium ion transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - # Class: (renal water transport) AnnotationAssertion(Annotation( "GOC:mtg_cardio") "The directed movement of water (H2O) by the renal system.") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0003097") AnnotationAssertion(rdfs:label "renal water transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (positive regulation of glomerular filtration) - -AnnotationAssertion(Annotation( "GOC:mtg_cardio") "Any process that activates or increases the frequency, rate or extent of glomerular filtration. Glomerular filtration is the processs whereby blood is filtered by the glomerulus into the renal tubule.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003104") -AnnotationAssertion(rdfs:label "positive regulation of glomerular filtration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of glomerular filtration) - -AnnotationAssertion(Annotation( "GOC:mtg_cardio") "Any process that stops, prevents, or reduces the frequency, rate or extent of glomerular filtration. Glomerular filtration is the processs whereby blood is filtered by the glomerulus into the renal tubule.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003105") -AnnotationAssertion(rdfs:label "negative regulation of glomerular filtration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (endodermal-mesodermal cell signaling) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "Any process that mediates the transfer of information from endodermal cells to mesodermal cells.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2009-09-22T03:10:29Z") -AnnotationAssertion(Annotation( "GOC:mah") "endodermal-mesodermal cell signalling") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003133") -AnnotationAssertion(rdfs:label "endodermal-mesodermal cell signaling") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (cardiogenic plate morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which the anatomical structures of the cardiogenic plate are generated and organized. The cardiogenic plate is the first recognizable structure derived from the heart field.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2009-09-22T04:12:18Z") -AnnotationAssertion(Annotation( "GOC:mtg_heart") "cardiac crescent morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003142") -AnnotationAssertion(rdfs:label "cardiogenic plate morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (embryonic heart tube morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which the anatomical structures of the embryonic heart tube are generated and organized. The embryonic heart tube is an epithelial tube that will give rise to the mature heart.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2009-09-22T04:21:17Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003143") -AnnotationAssertion(rdfs:label "embryonic heart tube morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (embryonic heart tube formation) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process that gives rise to the embryonic heart tube. This process pertains to the initial formation of a structure from unspecified parts. The embryonic heart tube is an epithelial tube that will give rise to the mature heart.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2009-09-22T04:22:34Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003144") -AnnotationAssertion(rdfs:label "embryonic heart tube formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (embryonic heart tube formation via epithelial folding) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process that gives rise to the embryonic heart tube by the cells of the heart field along a linear axis.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2009-09-22T04:26:03Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003145") -AnnotationAssertion(rdfs:label "embryonic heart tube formation via epithelial folding") -SubClassOf( ) - -# Class: (neural crest cell migration involved in heart formation) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The characteristic movement of a cell from the dorsal ridge of the neural tube towards the heart and that contributes to heart formation.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2009-09-22T04:29:55Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003147") -AnnotationAssertion(rdfs:label "neural crest cell migration involved in heart formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (outflow tract septum morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which the anatomical structures of the outflow tract septum are generated and organized. The outflow tract septum is a partition in the outflow tract.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2009-09-22T07:51:01Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003148") -AnnotationAssertion(rdfs:label "outflow tract septum morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (membranous septum morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which the membranous septum is generated and organized. The membranous septum is the upper part of ventricular septum.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2009-09-22T07:51:41Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003149") -AnnotationAssertion(rdfs:label "membranous septum morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (muscular septum morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which the muscular septum is generated and organized. The muscular septum is the lower part of the ventricular septum.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2009-09-22T07:53:28Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003150") -AnnotationAssertion(rdfs:label "muscular septum morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (outflow tract morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") Annotation( "UBERON:0004145") "The process in which the anatomical structures of the outflow tract are generated and organized. The outflow tract is the portion of the heart through which blood flows into the arteries.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2009-09-22T07:59:24Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003151") -AnnotationAssertion(rdfs:label "outflow tract morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (morphogenesis of an epithelial fold involved in embryonic heart tube formation) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The morphogenetic process in which an epithelial sheet bends along a linear axis, contributing to embryonic heart tube formation.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2009-09-23T10:10:24Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003152") -AnnotationAssertion(rdfs:label "morphogenesis of an epithelial fold involved in embryonic heart tube formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (regulation of animal organ formation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_heart") Annotation( "GOC:tb") "Any process that modulates the rate, frequency or extent of animal organ formation. Organ formation is the process pertaining to the initial formation of an organ from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure, such as inductive events, and ends when the structural rudiment of the organ is recognizable, such as a condensation of mesenchymal cells into the organ rudiment.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2009-09-30T11:21:09Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003156") -AnnotationAssertion(rdfs:label "regulation of animal organ formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (endocardium development) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process whose specific outcome is the progression of the endocardium over time, from its formation to the mature structure. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-01T12:42:27Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003157") -AnnotationAssertion(rdfs:label "endocardium development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (endothelium development) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process whose specific outcome is the progression of an endothelium over time, from its formation to the mature structure. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-01T12:50:57Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003158") -AnnotationAssertion(rdfs:label "endothelium development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (morphogenesis of an endothelium) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which the anatomical structure of an endothelium is generated and organized. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-01T01:34:06Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003159") -AnnotationAssertion(rdfs:label "morphogenesis of an endothelium") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (endocardium morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which the anatomical structure of the endocardium is generated and organized. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-01T01:37:26Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003160") -AnnotationAssertion(rdfs:label "endocardium morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cardiac conduction system development) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process whose specific outcome is the progression of the cardiac conduction system over time, from its formation to the mature structure. The cardiac conduction system consists of specialized cardiomyocytes that regulate the frequency of heart beat.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-01T01:57:16Z") -AnnotationAssertion(Annotation( "GOC:mtg_heart") "cardiac impulse conducting system development") -AnnotationAssertion(Annotation( "GOC:mtg_heart") "heart conduction system development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003161") -AnnotationAssertion(rdfs:label "cardiac conduction system development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (atrioventricular node development) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process whose specific outcome is the progression of the atrioventricular (AV) node over time, from its formation to the mature structure. The AV node is part of the cardiac conduction system that controls the timing of ventricle contraction by receiving electrical signals from the sinoatrial (SA) node and relaying them to the His-Purkinje system.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-01T02:05:13Z") -AnnotationAssertion(Annotation( "GOC:mtg_heart") "AV node development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003162") -AnnotationAssertion(rdfs:label "atrioventricular node development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (sinoatrial node development) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process whose specific outcome is the progression of the sinoatrial (SA) node over time, from its formation to the mature structure. The SA node is part of the cardiac conduction system that controls the timing of heart muscle contraction. It relays electrical signals to the AV node.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-01T02:06:09Z") -AnnotationAssertion(Annotation( "GOC:mtg_heart") "SA node development") -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mtg_cardiac_conduct_nov11") "SAN development") -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mtg_cardiac_conduct_nov11") "sinus node development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003163") -AnnotationAssertion(rdfs:label "sinoatrial node development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (His-Purkinje system development) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process whose specific outcome is the progression of the His-Purkinje system over time, from its formation to the mature structure. The His-Purkinje system receives signals from the AV node and is composed of the fibers that regulate cardiac muscle contraction in the ventricles.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-01T02:07:12Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003164") -AnnotationAssertion(rdfs:label "His-Purkinje system development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (Purkinje myocyte development) - -AnnotationAssertion(Annotation( "GOC:mtg_cardiac_conduct_nov11") Annotation( "GOC:mtg_heart") "The process whose specific outcome is the progression of a Purkinje myocyte over time, from its formation to the mature structure. The Purkinje myocyte (also known as cardiac Purkinje fiber) is part of the cardiac conduction system that receives signals from the bundle of His and innervates the ventricular cardiac muscle.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-01T02:07:50Z") -AnnotationAssertion( "cardiac Purkinje fiber development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003165") -AnnotationAssertion(rdfs:label "Purkinje myocyte development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (bundle of His development) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process whose specific outcome is the progression of the bundle of His over time, from its formation to the mature structure. The bundle of His is part of the His-Purkinje system that transmits signals from the AV node to the cardiac Purkinje fibers.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-01T02:08:43Z") -AnnotationAssertion(Annotation( "GOC:mtg_heart") "atrioventricular bundle development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003166") -AnnotationAssertion(rdfs:label "bundle of His development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (atrioventricular bundle cell differentiation) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell of the atrioventricular bundle. These cells are specialized cardiomyocytes that transmit signals from the AV node to the cardiac Purkinje fibers.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-01T02:48:23Z") -AnnotationAssertion(Annotation( "GOC:mtg_heart") "AV bundle cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003167") -AnnotationAssertion(rdfs:label "atrioventricular bundle cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (Purkinje myocyte differentiation) - -AnnotationAssertion(Annotation( "GOC:mtg_cardiac_conduct_nov11") Annotation( "GOC:mtg_heart") "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a Purkinje myocyte (also known as cardiac Purkinje fiber cell). These cells are specialized cardiomyocytes that receive signals from the bundle of His and innervate the ventricular cardiac muscle.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-01T02:49:54Z") -AnnotationAssertion( "cardiac Purkinje fiber cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003168") -AnnotationAssertion(rdfs:label "Purkinje myocyte differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (coronary vein morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which the anatomical structures of veins of the heart are generated and organized.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-08T10:45:41Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003169") -AnnotationAssertion(rdfs:label "coronary vein morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (heart valve development) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The progression of a heart valve over time, from its formation to the mature structure. A heart valve is a structure that restricts the flow of blood to different regions of the heart and forms from an endocardial cushion.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-08T10:50:09Z") -AnnotationAssertion(Annotation( "GOC:mtg_heart") "cardiac valve development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003170") -AnnotationAssertion(rdfs:label "heart valve development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (atrioventricular valve development) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The progression of the atrioventricular valve over time, from its formation to the mature structure.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-08T11:14:21Z") -AnnotationAssertion(Annotation( "GOC:mah") "AV valve development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003171") -AnnotationAssertion(rdfs:label "atrioventricular valve development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (sinoatrial valve development) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The progression of the sinoatrial valve over time, from its formation to the mature structure.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-08T11:15:39Z") -AnnotationAssertion(Annotation( "GOC:mah") "SA valve development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003172") -AnnotationAssertion(rdfs:label "sinoatrial valve development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (ventriculo bulbo valve development) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The progression of the ventriculo bulbo valve over time, from its formation to the mature structure.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-08T11:16:25Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003173") -AnnotationAssertion(rdfs:label "ventriculo bulbo valve development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (mitral valve development) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The progression of the mitral valve over time, from its formation to the mature structure.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-08T11:17:22Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003174") -AnnotationAssertion(rdfs:label "mitral valve development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (tricuspid valve development) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The progression of the tricuspid valve over time, from its formation to the mature structure.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-08T11:18:12Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003175") -AnnotationAssertion(rdfs:label "tricuspid valve development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (aortic valve development) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The progression of the aortic valve over time, from its formation to the mature structure.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-08T11:18:55Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003176") -AnnotationAssertion(rdfs:label "aortic valve development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (pulmonary valve development) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The progression of the pulmonary valve over time, from its formation to the mature structure.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-08T11:19:44Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003177") -AnnotationAssertion(rdfs:label "pulmonary valve development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (coronary sinus valve development) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The progression of the valve of the coronary sinus over time, from its formation to the mature structure.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-08T11:21:43Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003178") -AnnotationAssertion(rdfs:label "coronary sinus valve development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (heart valve morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which the structure of a heart valve is generated and organized.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-08T11:23:48Z") -AnnotationAssertion(Annotation( "GOC:vk") Annotation( "GOC:yaf") "heart valve remodeling") -AnnotationAssertion(Annotation( "GOC:vk") Annotation( "GOC:yaf") "heart valve remodelling") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003179") -AnnotationAssertion(rdfs:label "heart valve morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (aortic valve morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which the structure of the aortic valve is generated and organized.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-08T11:29:42Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003180") -AnnotationAssertion(rdfs:label "aortic valve morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (atrioventricular valve morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which the structure of the atrioventricular valve is generated and organized.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-08T11:31:59Z") -AnnotationAssertion(Annotation( "GOC:mah") "AV valve morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003181") -AnnotationAssertion(rdfs:label "atrioventricular valve morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (coronary sinus valve morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which the structure of the coronary sinus valve is generated and organized.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-08T11:33:31Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003182") -AnnotationAssertion(rdfs:label "coronary sinus valve morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (mitral valve morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which the structure of the mitral valve is generated and organized.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-08T12:02:01Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003183") -AnnotationAssertion(rdfs:label "mitral valve morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (pulmonary valve morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which the structure of the pulmonary valve is generated and organized.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-08T12:03:35Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003184") -AnnotationAssertion(rdfs:label "pulmonary valve morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (sinoatrial valve morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which the structure of the sinoatrial valve is generated and organized.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-08T12:04:52Z") -AnnotationAssertion(Annotation( "GOC:mah") "SA valve morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003185") -AnnotationAssertion(rdfs:label "sinoatrial valve morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (tricuspid valve morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which the structure of the tricuspid valve is generated and organized.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-08T12:05:45Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003186") -AnnotationAssertion(rdfs:label "tricuspid valve morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (ventriculo bulbo valve morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which the structure of the ventriculo bulbo valve is generated and organized.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-08T12:07:00Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003187") -AnnotationAssertion(rdfs:label "ventriculo bulbo valve morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (heart valve formation) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The developmental process pertaining to the initial formation of a heart valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-08T12:20:15Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003188") -AnnotationAssertion(rdfs:label "heart valve formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (aortic valve formation) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The developmental process pertaining to the initial formation of the aortic valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-08T01:05:44Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003189") -AnnotationAssertion(rdfs:label "aortic valve formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (atrioventricular valve formation) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The developmental process pertaining to the initial formation of the atrioventricular valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-08T01:07:28Z") -AnnotationAssertion(Annotation( "GOC:mah") "AV valve formation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003190") -AnnotationAssertion(rdfs:label "atrioventricular valve formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (coronary sinus valve formation) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The developmental process pertaining to the initial formation of the coronary sinus valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-08T01:09:04Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003191") -AnnotationAssertion(rdfs:label "coronary sinus valve formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (mitral valve formation) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The developmental process pertaining to the initial formation of the mitral valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-08T01:10:19Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003192") -AnnotationAssertion(rdfs:label "mitral valve formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (pulmonary valve formation) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The developmental process pertaining to the initial formation of the pulmonary valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-08T01:11:20Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003193") -AnnotationAssertion(rdfs:label "pulmonary valve formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (sinoatrial valve formation) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The developmental process pertaining to the initial formation of the sinoatrial valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-08T01:12:45Z") -AnnotationAssertion(Annotation( "GOC:mah") "SA valve formation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003194") -AnnotationAssertion(rdfs:label "sinoatrial valve formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (tricuspid valve formation) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The developmental process pertaining to the initial formation of the tricuspid valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-08T01:14:40Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003195") -AnnotationAssertion(rdfs:label "tricuspid valve formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (ventriculo bulbo valve formation) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The developmental process pertaining to the initial formation of the ventriculo bulbo valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-08T01:16:02Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003196") -AnnotationAssertion(rdfs:label "ventriculo bulbo valve formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (endocardial cushion development) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The progression of a cardiac cushion over time, from its initial formation to the mature structure. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-08T01:17:43Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003197") -AnnotationAssertion(rdfs:label "endocardial cushion development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (endocardial cushion morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which the anatomical structure of the endocardial cushion is generated and organized. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-08T01:43:22Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003203") -AnnotationAssertion(rdfs:label "endocardial cushion morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cardiac skeleton development) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The progression of the cardiac skeleton over time, from its formation to the mature structure. The cardiac skeleton is a specialized extracellular matrix that separates the atria from the ventricles and provides physical support for the heart.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-13T09:05:04Z") -AnnotationAssertion(Annotation( "GOC:mtg_heart") "heart fibrous skeleton development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003204") -AnnotationAssertion(rdfs:label "cardiac skeleton development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cardiac chamber development) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The progression of a cardiac chamber over time, from its formation to the mature structure. A cardiac chamber is an enclosed cavity within the heart.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-13T09:11:18Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003205") -AnnotationAssertion(rdfs:label "cardiac chamber development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cardiac chamber morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which a cardiac chamber is generated and organized. A cardiac chamber is an enclosed cavity within the heart.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-13T09:14:51Z") -AnnotationAssertion(Annotation( "GOC:mtg_heart") "heart chamber morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003206") -AnnotationAssertion(rdfs:label "cardiac chamber morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cardiac chamber formation) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The developmental process pertaining to the initial formation of a cardiac chamber from unspecified parts. A cardiac chamber is an enclosed cavity within the heart.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-13T09:29:13Z") -AnnotationAssertion(Annotation( "GOC:mtg_heart") "heart chamber formation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003207") -AnnotationAssertion(rdfs:label "cardiac chamber formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cardiac ventricle morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which the cardiac ventricle is generated and organized. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-13T09:38:44Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003208") -AnnotationAssertion(rdfs:label "cardiac ventricle morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cardiac atrium morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which the cardiac atrium is generated and organized. A cardiac atrium receives blood from a vein and pumps it to a cardiac ventricle.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-13T09:39:44Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003209") -AnnotationAssertion(rdfs:label "cardiac atrium morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cardiac atrium formation) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The developmental process pertaining to the initial formation of a cardiac atrium from unspecified parts. A cardiac atrium receives blood from a vein and pumps it to a cardiac ventricle.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-13T09:44:25Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003210") -AnnotationAssertion(rdfs:label "cardiac atrium formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cardiac ventricle formation) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The developmental process pertaining to the initial formation of a cardiac ventricle from unspecified parts. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-13T09:46:27Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003211") -AnnotationAssertion(rdfs:label "cardiac ventricle formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cardiac left atrium morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which the left cardiac atrium is generated and organized.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-13T09:48:16Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003212") -AnnotationAssertion(rdfs:label "cardiac left atrium morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (cardiac right atrium morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which the right cardiac atrium is generated and organized.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-13T09:49:03Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003213") -AnnotationAssertion(rdfs:label "cardiac right atrium morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (cardiac left ventricle morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which the left cardiac ventricle is generated and organized.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-13T09:50:08Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003214") -AnnotationAssertion(rdfs:label "cardiac left ventricle morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (cardiac right ventricle morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which the right cardiac ventricle is generated and organized.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-13T09:50:57Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003215") -AnnotationAssertion(rdfs:label "cardiac right ventricle morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (cardiac left atrium formation) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The developmental process pertaining to the initial formation of a left cardiac atrium from unspecified parts.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-13T09:52:31Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003216") -AnnotationAssertion(rdfs:label "cardiac left atrium formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cardiac right atrium formation) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The developmental process pertaining to the initial formation of a cardiac right atrium from unspecified parts.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-13T09:53:12Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003217") -AnnotationAssertion(rdfs:label "cardiac right atrium formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cardiac left ventricle formation) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The developmental process pertaining to the initial formation of a left cardiac ventricle from unspecified parts.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-13T09:54:33Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003218") -AnnotationAssertion(rdfs:label "cardiac left ventricle formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cardiac right ventricle formation) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The developmental process pertaining to the initial formation of a right cardiac ventricle from unspecified parts.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-13T09:55:38Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003219") -AnnotationAssertion(rdfs:label "cardiac right ventricle formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (left ventricular cardiac muscle tissue morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which the anatomical structures of left cardiac ventricle muscle are generated and organized.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-13T10:18:05Z") -AnnotationAssertion(Annotation( "GOC:mtg_heart") "left ventricular myocardium morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003220") -AnnotationAssertion(rdfs:label "left ventricular cardiac muscle tissue morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (right ventricular cardiac muscle tissue morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which the anatomical structures of the right cardiac ventricle muscle are generated and organized.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-13T10:26:33Z") -AnnotationAssertion(Annotation( "GOC:mtg_heart") "right ventricle myocardium morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003221") -AnnotationAssertion(rdfs:label "right ventricular cardiac muscle tissue morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (ventricular trabecula myocardium morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which the anatomical structures of the trabecular cardiac ventricle muscle are generated and organized.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-13T10:33:00Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") "trabecula carnea morphogenesis") -AnnotationAssertion( "GO:0003222") -AnnotationAssertion(rdfs:label "ventricular trabecula myocardium morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (ventricular compact myocardium morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which the anatomical structures of the compact cardiac ventricle muscle are generated and organized.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-13T10:34:21Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003223") -AnnotationAssertion(rdfs:label "ventricular compact myocardium morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (left ventricular compact myocardium morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which the anatomical structures of cardiac left ventricular compact myocardium are generated and organized.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-13T10:43:36Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003224") -AnnotationAssertion(rdfs:label "left ventricular compact myocardium morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (left ventricular trabecular myocardium morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which the anatomical structures of cardiac left ventricular trabecular myocardium are generated and organized.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-13T10:45:09Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003225") -AnnotationAssertion(rdfs:label "left ventricular trabecular myocardium morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (right ventricular compact myocardium morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which the anatomical structures of the right ventricular compact myocardium are generated and organized.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-13T10:48:42Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003226") -AnnotationAssertion(rdfs:label "right ventricular compact myocardium morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (right ventricular trabecular myocardium morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which the anatomical structures of the right ventricular myocardium are generated and organized.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-13T10:50:59Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003227") -AnnotationAssertion(rdfs:label "right ventricular trabecular myocardium morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (atrial cardiac muscle tissue development) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process whose specific outcome is the progression of cardiac muscle of the atrium over time, from its formation to the mature structure.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/22614"^^xsd:anyURI) -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-13T10:53:18Z") -AnnotationAssertion(Annotation( "GOC:mtg_heart") "atrial myocardium development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003228") -AnnotationAssertion(rdfs:label "atrial cardiac muscle tissue development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (ventricular cardiac muscle tissue development) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process whose specific outcome is the progression of ventricular cardiac muscle over time, from its formation to the mature structure.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-13T10:56:01Z") -AnnotationAssertion(Annotation( "GOC:mtg_heart") "ventricular myocardium development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003229") -AnnotationAssertion(rdfs:label "ventricular cardiac muscle tissue development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cardiac atrium development) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process whose specific outcome is the progression of a cardiac atrium over time, from its formation to the mature structure. A cardiac atrium receives blood from a vein and pumps it to a cardiac ventricle.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-13T11:02:07Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003230") -AnnotationAssertion(rdfs:label "cardiac atrium development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (cardiac ventricle development) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process whose specific outcome is the progression of a cardiac ventricle over time, from its formation to the mature structure. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-13T11:03:16Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003231") -AnnotationAssertion(rdfs:label "cardiac ventricle development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (bulbus arteriosus development) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process whose specific outcome is the progression of the bulbus arteriosus over time, from its formation to the mature structure. The bulbus arteriosus is an elastic heart chamber.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-13T11:05:36Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003232") -AnnotationAssertion(rdfs:label "bulbus arteriosus development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (bulbus arteriosus morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which the bulbus arteriosus is generated and organized. The bulbus arteriosus is an elastic cardiac chamber.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-13T11:07:30Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003233") -AnnotationAssertion(rdfs:label "bulbus arteriosus morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (bulbus arteriosus formation) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The developmental process pertaining to the initial formation of the bulbus arteriosus from unspecified parts. The bulbus arteriosus is an elastic chamber of the heart.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-13T11:10:02Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003234") -AnnotationAssertion(rdfs:label "bulbus arteriosus formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (sinus venosus development) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The progression of the sinus venosus over time, from its formation to the mature structure. The sinus venosus is a heart chamber attached to the atrium on the venous side of the embryonic heart.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-13T11:12:34Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003235") -AnnotationAssertion(rdfs:label "sinus venosus development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (sinus venosus morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which the sinus venosus is generated and organized. The sinus venosus is a heart chamber attached to the atrium on the venous side of the embryonic heart.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-13T11:16:52Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003236") -AnnotationAssertion(rdfs:label "sinus venosus morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (sinus venosus formation) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The developmental process pertaining to the initial formation of the sinus venosus from unspecified parts. The sinus venosus is a heart chamber attached to the atrium on the venous side of the embryonic heart.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-13T11:18:34Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003237") -AnnotationAssertion(rdfs:label "sinus venosus formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (conus arteriosus development) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The progression of the conus arteriosus over time, from its formation to the mature structure. The conus arteriosus is a valved chamber with thick muscular walls stemming from the ventricle and connecting to the pulmonary trunk.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-13T11:20:57Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003238") -AnnotationAssertion(rdfs:label "conus arteriosus development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (conus arteriosus morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which the conus arteriosus is generated and organized. The conus arteriosus is a valved chamber with thick muscular walls stemming from the ventricle and connecting to the pulmonary trunk.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-13T11:25:04Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003239") -AnnotationAssertion(rdfs:label "conus arteriosus morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (conus arteriosus formation) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The developmental process pertaining to the initial formation of the conus arteriosus from unspecified parts. The conus arteriosus is a valved chamber with thick muscular walls stemming from the ventricle and connecting to the pulmonary trunk.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-13T11:25:47Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003240") -AnnotationAssertion(rdfs:label "conus arteriosus formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (growth involved in heart morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "Developmental growth that contributes to the shaping of the heart.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-13T11:28:46Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003241") -AnnotationAssertion(rdfs:label "growth involved in heart morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cardiac muscle tissue growth involved in heart morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The developmental growth of cardiac muscle tissue that contributes to the shaping of the heart.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-13T11:44:21Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003245") -AnnotationAssertion(rdfs:label "cardiac muscle tissue growth involved in heart morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (heart capillary growth) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The increase in heart capillaries that accompanies physiological hypertrophy of cardiac muscle.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-13T11:53:12Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003248") -AnnotationAssertion(rdfs:label "heart capillary growth") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cell proliferation involved in heart valve morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The multiplication or reproduction of cells that contributes to the shaping of a heart valve.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-13T01:59:19Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003249") -AnnotationAssertion(rdfs:label "cell proliferation involved in heart valve morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of cell proliferation involved in heart valve morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "Any process that modulates the rate, frequency or extent of cell proliferation that contributes to the shaping of a heart valve.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-13T02:03:42Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003250") -AnnotationAssertion(rdfs:label "regulation of cell proliferation involved in heart valve morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of cell proliferation involved in heart valve morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "Any process that increases the rate, frequency or extent of cell proliferation that contributes to the shaping of a heart valve.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-13T02:07:20Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003251") -AnnotationAssertion(rdfs:label "positive regulation of cell proliferation involved in heart valve morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of cell proliferation involved in heart valve morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "Any process that decreases the rate, frequency or extent of cell proliferation that contributes to the shaping of a heart valve.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-13T02:10:39Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003252") -AnnotationAssertion(rdfs:label "negative regulation of cell proliferation involved in heart valve morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cardiac neural crest cell migration involved in outflow tract morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The orderly movement of a neural crest cell from one site to another that will contribute to the morphogenesis of the outflow tract.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-13T02:14:16Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003253") -AnnotationAssertion(rdfs:label "cardiac neural crest cell migration involved in outflow tract morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cardioblast migration) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The orderly movement of a cardiac progenitor cell to form the heart field. Cardiac progenitor cells are non-terminally differentiated, mesoderm-derived cells that are committed to differentiate into cells of the heart. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-15T01:52:25Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003260") -AnnotationAssertion(rdfs:label "cardioblast migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (endocardial cushion formation) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") Annotation( "PMID:15797462") "The developmental process pertaining to the initial formation of an endocardial cushion. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-20T08:53:19Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003272") -AnnotationAssertion(rdfs:label "endocardial cushion formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cell migration involved in endocardial cushion formation) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The orderly movement of a cell from one site to another that will contribute to the formation of an endocardial cushion. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-20T09:08:44Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003273") -AnnotationAssertion(rdfs:label "cell migration involved in endocardial cushion formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (apoptotic process involved in outflow tract morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:mtg_heart") "Any apoptotic process that contributes to the shaping of the outflow tract. The outflow tract is the portion of the heart through which blood flows into the arteries.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-20T09:30:01Z") -AnnotationAssertion( "apoptosis involved in outflow tract morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003275") -AnnotationAssertion(rdfs:label "apoptotic process involved in outflow tract morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (apoptotic process involved in heart valve morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:mtg_heart") "Any apoptotic process that contributes to the shaping of a heart valve.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-20T09:34:29Z") -AnnotationAssertion( "apoptosis involved in heart valve morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003276") -AnnotationAssertion(rdfs:label "apoptotic process involved in heart valve morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (apoptotic process involved in endocardial cushion morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:mtg_heart") "Any apoptotic process that contributes to the shaping of an endocardial cushion. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-20T09:37:03Z") -AnnotationAssertion( "apoptosis involved in endocardial cushion morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003277") -AnnotationAssertion(rdfs:label "apoptotic process involved in endocardial cushion morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (apoptotic process involved in heart morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:mtg_heart") "Any apoptotic process that contributes to the shaping of the heart.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-20T09:40:22Z") -AnnotationAssertion( "apoptosis involved in heart morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003278") -AnnotationAssertion(rdfs:label "apoptotic process involved in heart morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cardiac septum development) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The progression of a cardiac septum over time, from its initial formation to the mature structure.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-20T09:45:13Z") -AnnotationAssertion(Annotation( "GOC:mtg_heart") "heart septum development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003279") -AnnotationAssertion(rdfs:label "cardiac septum development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (ventricular septum development) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The progression of the ventricular septum over time from its formation to the mature structure.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-20T10:04:51Z") -AnnotationAssertion(Annotation( "GOC:mtg_heart") "interventricular septum development") -AnnotationAssertion(Annotation( "GOC:mtg_heart") "septum inferius development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003281") -AnnotationAssertion(rdfs:label "ventricular septum development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (ventricular septum intermedium development) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The progression of the ventricular septum intermedium over time, from its formation to the mature structure.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-20T10:09:53Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003282") -AnnotationAssertion(rdfs:label "ventricular septum intermedium development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (atrial septum development) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The progression of the atrial septum over time, from its initial formation to the mature structure.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-20T10:10:38Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003283") -AnnotationAssertion(rdfs:label "atrial septum development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (septum primum development) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The progression of the septum primum over time, from its formation to the mature structure.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-20T10:12:26Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003284") -AnnotationAssertion(rdfs:label "septum primum development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (septum secundum development) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The progression of the septum secundum over time, from its initial formation to the mature structure.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-20T10:21:13Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003285") -AnnotationAssertion(rdfs:label "septum secundum development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (atrial septum intermedium development) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The progression of the atrial septum intermedium over time, from its formation to the mature structure.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-20T10:23:52Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003286") -AnnotationAssertion(rdfs:label "atrial septum intermedium development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (ventricular septum intermedium morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The developmental process in which a ventricular septum intermedium is generated and organized.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-20T10:58:48Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003288") -AnnotationAssertion(rdfs:label "ventricular septum intermedium morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (atrial septum primum morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which anatomical structure of an atrial septum primum is generated and organized.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-20T10:32:32Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003289") -AnnotationAssertion(rdfs:label "atrial septum primum morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (atrial septum secundum morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which anatomical structure of an atrial septum secundum is generated and organized.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-20T10:33:57Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003290") -AnnotationAssertion(rdfs:label "atrial septum secundum morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (atrial septum intermedium morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which anatomical structure of an atrial septum intermedium is generated and organized.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-20T10:35:04Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003291") -AnnotationAssertion(rdfs:label "atrial septum intermedium morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cardiac septum cell differentiation) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which an endocardial cushion cell becomes a cell of a cardiac septum.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-20T11:03:46Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003292") -AnnotationAssertion(rdfs:label "cardiac septum cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (heart valve cell differentiation) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which an endocardial cushion cell give rise to a cell that is part of a heart valve.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-20T11:06:46Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003293") -AnnotationAssertion(rdfs:label "heart valve cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (physiological muscle hypertrophy) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The enlargement or overgrowth of all or part of a muscle organ or tissue due to an increase in the size of its muscle cells. Physiological hypertrophy is a normal process during development.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-22T09:24:51Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003298") -AnnotationAssertion(rdfs:label "physiological muscle hypertrophy") -SubClassOf( ) - -# Class: (cardiac muscle hypertrophy) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The enlargement or overgrowth of all or part of the heart muscle due to an increase in size of cardiac muscle cells without cell division.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-22T10:33:56Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003300") -AnnotationAssertion(rdfs:label "cardiac muscle hypertrophy") -SubClassOf( ) - -# Class: (physiological cardiac muscle hypertrophy) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mtg_cardiac_conduct_nov11") Annotation( "GOC:mtg_heart") "The enlargement or overgrowth of all or part of the heart muscle due to an increase in size of cardiac muscle cells without cell division. This process contributes to the developmental growth of the heart.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-22T10:38:10Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003301") -AnnotationAssertion(rdfs:label "physiological cardiac muscle hypertrophy") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (type B pancreatic cell differentiation) - -AnnotationAssertion(Annotation( "CL:0000169") Annotation( "GOC:dph") Annotation( "PMID:11076772") "The process in which relatively unspecialized cells acquire specialized structural and/or functional features of a type B pancreatic cell. A type B pancreatic cell is a cell located towards center of the islets of Langerhans that secretes insulin.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-26T09:27:23Z") -AnnotationAssertion(Annotation( "GOC:mah") "pancreatic B cell differentiation") -AnnotationAssertion(Annotation( "GOC:dph") "pancreatic beta cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003309") -AnnotationAssertion(rdfs:label "type B pancreatic cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (pancreatic A cell differentiation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:11076772") "The process in which relatively unspecialized cells acquire specialized structural and functional features of a pancreatic A cell. A pancreatic A cell is a cell in the pancreas that secretes glucagon.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-26T09:28:05Z") -AnnotationAssertion(Annotation( "GOC:dph") "pancreatic alpha cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003310") -AnnotationAssertion(rdfs:label "pancreatic A cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (pancreatic D cell differentiation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:11076772") "The process in which relatively unspecialized cells acquire specialized structural and functional features that characterize a pancreatic delta cell. A delta cell is a cell of the pancreas that produces somatostatin.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-26T09:30:27Z") -AnnotationAssertion(Annotation( "GOC:dph") "pancreatic delta cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003311") -AnnotationAssertion(rdfs:label "pancreatic D cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (pancreatic PP cell differentiation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:11076772") "The process in which relatively unspecialized cells acquire specialized structural and functional features of a pancreatic polypeptide-producing cell. A pancreatic polypeptide-producing cell is a cell in the pancreas that produces pancreatic polypeptide.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-26T09:32:32Z") -AnnotationAssertion(Annotation( "GOC:dph") "pancreatic polypeptide-producing cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003312") -AnnotationAssertion(rdfs:label "pancreatic PP cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (heart rudiment development) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The progression of the heart rudiment over time, from its initial formation to the mature structure. The heart rudiment is a cone-like structure that is formed when myocardial progenitor cells of the heart field fuse at the midline. The heart rudiment is the first structure of the heart tube.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-27T08:32:40Z") -AnnotationAssertion(Annotation( "GOC:mtg_heart") "heart cone development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003313") -AnnotationAssertion(rdfs:label "heart rudiment development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (heart rudiment morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which the anatomical structures of the heart rudiment are generated and organized.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-27T08:38:04Z") -AnnotationAssertion(Annotation( "GOC:mtg_heart") "heart cone morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003314") -AnnotationAssertion(rdfs:label "heart rudiment morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (heart rudiment formation) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The developmental process pertaining to the initial formation of the heart rudiment.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-27T08:43:37Z") -AnnotationAssertion(Annotation( "GOC:mtg_heart") "heart cone formation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003315") -AnnotationAssertion(rdfs:label "heart rudiment formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (pancreatic A cell development) - -AnnotationAssertion(Annotation( "GOC:dph") "The process whose specific outcome is the progression of a pancreatic A cell over time, from its formation to the mature structure. A pancreatic A cell is a cell in the pancreas that secretes glucagon.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-11-02T08:13:55Z") -AnnotationAssertion(Annotation( "GOC:dph") "pancreatic alpha cell development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003322") -AnnotationAssertion(rdfs:label "pancreatic A cell development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (type B pancreatic cell development) - -AnnotationAssertion(Annotation( "CL:0000169") Annotation( "GOC:dph") "The process whose specific outcome is the progression of a type B pancreatic cell over time, from its formation to the mature structure. A type B pancreatic cell is a cell located towards center of the islets of Langerhans that secretes insulin.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-11-02T08:20:11Z") -AnnotationAssertion(Annotation( "GOC:mah") "pancreatic B cell development") -AnnotationAssertion(Annotation( "GOC:dph") "pancreatic beta cell development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003323") -AnnotationAssertion(rdfs:label "type B pancreatic cell development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (pancreatic D cell development) - -AnnotationAssertion(Annotation( "GOC:dph") "The process whose specific outcome is the progression of a pancreatic delta cell over time, from its formation to the mature structure. A delta cell is a cell of the pancreas that produces somatostatin.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-11-02T08:23:26Z") -AnnotationAssertion(Annotation( "GOC:dph") "pancreatic delta cell development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003324") -AnnotationAssertion(rdfs:label "pancreatic D cell development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (pancreatic PP cell development) - -AnnotationAssertion(Annotation( "GOC:dph") "The process whose specific outcome is the progression of a pancreatic PP cell over time, from its formation to the mature structure. A pancreatic polypeptide-producing cell is a cell in the pancreas that produces pancreatic polypeptide.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-11-02T08:25:03Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003325") -AnnotationAssertion(rdfs:label "pancreatic PP cell development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (regulation of extracellular matrix constituent secretion) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the rate, frequency, or extent of the controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell or a group of cells.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-11-02T02:07:40Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003330") -AnnotationAssertion(rdfs:label "regulation of extracellular matrix constituent secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of extracellular matrix constituent secretion) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that increases the rate, frequency, or extent of the controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell or a group of cells.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-11-02T02:11:22Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003331") -AnnotationAssertion(rdfs:label "positive regulation of extracellular matrix constituent secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of extracellular matrix constituent secretion) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that decreases the rate, frequency, or extent the controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell or a group of cells.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-11-02T02:13:49Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003332") -AnnotationAssertion(rdfs:label "negative regulation of extracellular matrix constituent secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (amino acid transmembrane transport) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "The process in which an amino acid is transported across a membrane.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-11-02T02:36:11Z") -AnnotationAssertion( "amino acid membrane transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003333") -AnnotationAssertion(rdfs:comment "Note that this term is not intended for use in annotating lateral movement within membranes.") -AnnotationAssertion(rdfs:label "amino acid transmembrane transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (keratinocyte development) - -AnnotationAssertion(Annotation( "GOC:dph") "The process whose specific outcome is the progression of a keratinocyte over time, from its formation to the mature structure.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-11-24T08:55:57Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003334") -AnnotationAssertion(rdfs:label "keratinocyte development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (corneocyte development) - -AnnotationAssertion(Annotation( "GOC:dph") "The process whose specific outcome is the progression of the corneocyte over time, from its formation to the mature structure. A corneocyte is the last stage of development of a keratinocyte where the keratinocyte flattens, loses its nucleus and eventually delaminates from the epidermis.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-11-24T09:01:02Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003335") -AnnotationAssertion(rdfs:label "corneocyte development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (mesenchymal to epithelial transition involved in metanephros morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:yaf") "A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-11-24T09:29:49Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") "metanephric mesenchyme to epithelial transition") -AnnotationAssertion( "GO:0003337") -AnnotationAssertion(rdfs:label "mesenchymal to epithelial transition involved in metanephros morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (metanephros morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:yaf") "The process in which the anatomical structures of the metanephros are generated and organized.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-11-24T09:32:09Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003338") -AnnotationAssertion(rdfs:label "metanephros morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") "Any process that modulates the rate, frequency or extent of the transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-11-24T09:43:04Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003339") -AnnotationAssertion(rdfs:label "regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:yaf") "Any process that decreases the rate, frequency or extent of the transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-11-24T09:46:12Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003340") -AnnotationAssertion(rdfs:label "negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cilium movement) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:jl") "The directed, self-propelled movement of a cilium.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/19809"^^xsd:anyURI) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-11-24T09:56:26Z") -AnnotationAssertion( "GO:0036142") -AnnotationAssertion( "microtubule-based flagellum movement") -AnnotationAssertion(Annotation( "GOC:bf") "flagellar movement") -AnnotationAssertion( "flagellum movement") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "ciliary motility") -AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "cilium beating") -AnnotationAssertion( "flagellar motility") -AnnotationAssertion( "GO:0003341") -AnnotationAssertion(rdfs:comment "Note that we deem cilium and microtubule-based flagellum to be equivalent.") -AnnotationAssertion(rdfs:label "cilium movement") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) -SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) -SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) -SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) -SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) -SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) -SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) -SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) -SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) -SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) -SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) -SubClassOf( ObjectAllValuesFrom( )) -DisjointClasses( ObjectSomeValuesFrom( )) -DisjointClasses( ObjectSomeValuesFrom( )) -DisjointClasses( ObjectSomeValuesFrom( )) -DisjointClasses( ObjectSomeValuesFrom( )) -DisjointClasses( ObjectSomeValuesFrom( )) -DisjointClasses( ObjectSomeValuesFrom( )) - -# Class: (proepicardium development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:18722343") "The progression of the proepicardium from its formation to the mature structure. The proepicardium is an outpouching of the septum transversum.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-12-01T10:30:17Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003342") -AnnotationAssertion(rdfs:label "proepicardium development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (septum transversum development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:18722343") "The progression of the septum transversum from its initial formation to the mature structure. The septum transversum is a portion of the trunk mesenchyme.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-12-01T10:40:17Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003343") -AnnotationAssertion(rdfs:label "septum transversum development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (pericardium morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:18722343") "The process in which the anatomical structure of the pericardium is generated and organized.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-12-01T10:46:34Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003344") -AnnotationAssertion(rdfs:label "pericardium morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cardiac endothelial cell differentiation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:18722343") "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cardiac endothelial cell.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-12-01T11:12:05Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003348") -AnnotationAssertion(rdfs:label "cardiac endothelial cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (pulmonary myocardium development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:17638577") "The progression of the pulmonary myocardium over time, from its initial formation to the mature structure. The pulmonary myocardium is the myocardial tissue present in the pulmonary vein.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-12-01T12:50:06Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003350") -AnnotationAssertion(rdfs:label "pulmonary myocardium development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (epithelial cilium movement involved in extracellular fluid movement) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:krc") "The directed, self-propelled movement of cilia of epithelial cells. Depending on the type of cell, there may be one or many cilia per cell. This movement is usually coordinated between many epithelial cells, and serves to move extracellular fluid.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/17181"^^xsd:anyURI) -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-12-03T10:08:25Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:cilia") "cilium movement involved in fluid flow") -AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "epithelial cilium beating") -AnnotationAssertion( "GO:0003351") -AnnotationAssertion(rdfs:label "epithelial cilium movement involved in extracellular fluid movement") -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of cilium movement) - -AnnotationAssertion(Annotation( "GOC:dph") "Any process that modulates the rate, frequency, or extent of cilium movement, the directed, self-propelled movement of a cilium.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-12-03T10:12:00Z") -AnnotationAssertion( "GO:1900172") -AnnotationAssertion( "regulation of microtubule-based flagellum movement") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of flagellar movement") -AnnotationAssertion( "regulation of flagellum movement") -AnnotationAssertion( "GO:0003352") -AnnotationAssertion(rdfs:comment "Note that we deem cilium and microtubule-based flagellum to be equivalent.") -AnnotationAssertion(rdfs:label "regulation of cilium movement") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of cilium movement) - -AnnotationAssertion(Annotation( "GOC:dph") "Any process that increases the rate, frequency, or extent of cilium movement, the directed, self-propelled movement of a cilium.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-12-03T10:16:10Z") -AnnotationAssertion( "GO:1900174") -AnnotationAssertion( "positive regulation of microtubule-based flagellum movement") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of flagellar movement") -AnnotationAssertion( "positive regulation of flagellum movement") -AnnotationAssertion( "GO:0003353") -AnnotationAssertion(rdfs:comment "Note that we deem cilium and microtubule-based flagellum to be equivalent.") -AnnotationAssertion(rdfs:label "positive regulation of cilium movement") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of cilium movement) - -AnnotationAssertion(Annotation( "GOC:dph") "Any process that decreases the rate, frequency, or extent of cilium movement, the directed, self-propelled movement of a cilium.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-12-03T10:17:47Z") -AnnotationAssertion( "GO:1900173") -AnnotationAssertion( "negative regulation of microtubule-based flagellum movement") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "negative regulation of flagellum movement") -AnnotationAssertion( "GO:0003354") -AnnotationAssertion(rdfs:comment "Note that we deem cilium and microtubule-based flagellum to be equivalent.") -AnnotationAssertion(rdfs:label "negative regulation of cilium movement") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cilium movement involved in otolith formation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:krc") Annotation( "PMID:19043402") "The directed, self-propelled movement of cilia of inner ear epithelial cells, resulting the aggregation of otolith seed particles.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/17181"^^xsd:anyURI) -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-12-03T10:21:08Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003355") -AnnotationAssertion(rdfs:label "cilium movement involved in otolith formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (noradrenergic neuron differentiation) - -AnnotationAssertion(Annotation( "GOC:dph") "The process in which a relatively unspecialized cell acquires specialized features of an noradrenergic neuron, a neuron that secretes noradrenaline.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-12-03T10:34:30Z") -AnnotationAssertion(Annotation( "GOC:dph") "norepinephrine secreting neuron differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003357") -AnnotationAssertion(rdfs:label "noradrenergic neuron differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (noradrenergic neuron development) - -AnnotationAssertion(Annotation( "GOC:dph") "The process whose specific outcome is the progression of a noradrenergic neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-12-03T10:38:37Z") -AnnotationAssertion(Annotation( "GOC:dph") "norepinephrine secreting neuron development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003358") -AnnotationAssertion(rdfs:label "noradrenergic neuron development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (brainstem development) - -AnnotationAssertion(Annotation( "GOC:dph") "The progression of the brainstem from its formation to the mature structure. The brainstem is the part of the brain that connects the brain with the spinal cord.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-12-03T10:47:20Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003360") -AnnotationAssertion(rdfs:label "brainstem development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (noradrenergic neuron differentiation involved in brainstem development) - -AnnotationAssertion(Annotation( "GOC:dph") "The process in which a relatively unspecialized cell acquires specialized features of an noradrenergic neuron that is part of the brainstem.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-12-03T10:53:30Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003361") -AnnotationAssertion(rdfs:label "noradrenergic neuron differentiation involved in brainstem development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (establishment of cell polarity involved in ameboidal cell migration) - -AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "The specification and formation of anisotropic intracellular organization that contributes to the self-propelled directed movement of an ameboid cell.") -AnnotationAssertion( ) -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-12-08T04:50:41Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003365") -AnnotationAssertion(rdfs:label "establishment of cell polarity involved in ameboidal cell migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) -DisjointClasses( ObjectSomeValuesFrom( )) - -# Class: (establishment or maintenance of cytoskeleton polarity involved in ameboidal cell migration) - -AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures that contribute to the cell polarity of a migrating ameboid cell.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-12-08T05:42:46Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003371") -AnnotationAssertion(rdfs:label "establishment or maintenance of cytoskeleton polarity involved in ameboidal cell migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (establishment of cell polarity involved in gastrulation cell migration) - -AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "The specification and formation of anisotropic intracellular organization that contributes to the self-propelled directed movement of an ameboid cell taking part in gastrulation.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-12-09T06:54:44Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003379") -AnnotationAssertion(rdfs:label "establishment of cell polarity involved in gastrulation cell migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (establishment or maintenance of cytoskeleton polarity involved in gastrulation) - -AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures that contribute to the cell polarity of a migrating ameboid cell taking part in gastrulation.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-12-09T07:10:57Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003380") -AnnotationAssertion(rdfs:label "establishment or maintenance of cytoskeleton polarity involved in gastrulation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (epithelial cell morphogenesis involved in gastrulation) - -AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "The change in form that occurs when an epithelial cell progresses from it initial formation to its mature state, contributing to the process of gastrulation.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-12-09T07:18:53Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003381") -AnnotationAssertion(rdfs:label "epithelial cell morphogenesis involved in gastrulation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (epithelial cell morphogenesis) - -AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "The change in form that occurs when an epithelial cell progresses from its initial formation to its mature state.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-12-09T07:21:06Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003382") -AnnotationAssertion(rdfs:label "epithelial cell morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cell-cell signaling involved in amphid sensory organ development) - -AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that mediates the transfer of information from one cell to another and contributes to the progression of an amphid sensory organ over time, from its formation to the mature state.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-12-09T08:55:37Z") -AnnotationAssertion(Annotation( "GOC:mah") "cell-cell signalling involved in amphid sensory organ development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003385") -AnnotationAssertion(rdfs:label "cell-cell signaling involved in amphid sensory organ development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (amphid sensory organ development) - -AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "The progression of the amphid sensory organ over time, from its formation to the mature structure. Amphid sensory organs are the sensory organs of nematodes.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-12-09T09:09:20Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003386") -AnnotationAssertion(rdfs:label "amphid sensory organ development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (neuron differentiation involved in amphid sensory organ development) - -AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "The process in which a relatively unspecialized cell acquires specialized features of a neuron that contributes to the progression of the amphid sensory gland.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-12-09T09:15:00Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003387") -AnnotationAssertion(rdfs:label "neuron differentiation involved in amphid sensory organ development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (neuron development involved in amphid sensory organ development) - -AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "The process whose specific outcome is the progression of a neuron over time, that contributes to the development of the amphid sensory organ.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-12-09T09:18:06Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003388") -AnnotationAssertion(rdfs:label "neuron development involved in amphid sensory organ development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (glial cell differentiation involved in amphid sensory organ development) - -AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "The process in which a relatively unspecialized cell acquires the specialized features of a glial cell of the amphid sensory organ.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-12-09T09:55:27Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003398") -AnnotationAssertion(rdfs:label "glial cell differentiation involved in amphid sensory organ development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (optic vesicle formation) - -AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "The developmental process pertaining to the initial formation of the optic vesicle from the lateral wall of the forebrain. This process begins with the specific processes that contribute to the appearance of the vesicle and ends when the vesicle has evaginated. The optic vesicle is the evagination of neurectoderm that precedes formation of the optic cup.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-12-21T01:42:37Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003403") -AnnotationAssertion(rdfs:label "optic vesicle formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (optic vesicle morphogenesis) - -AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "The developmental process pertaining to the formation and shaping of the optic vesicle. This process begins with the specific processes that contribute to the appearance of the vesicle and ends when the vesicle has evaginated. The optic vesicle is the evagination of neurectoderm that precedes formation of the optic cup.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-12-21T01:54:34Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003404") -AnnotationAssertion(rdfs:label "optic vesicle morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (retinal pigment epithelium development) - -AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "The progression of the retinal pigment epithelium over time, from its initial formation to the mature structure. The retinal pigment epithelium is the melanin-containing layer of cells between the retina and the choroid that absorbs scattered and reflected light and removes waste products produced by the photoreceptor cells.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-12-21T02:04:27Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "RPE development") -AnnotationAssertion( "GO:0003406") -AnnotationAssertion(rdfs:label "retinal pigment epithelium development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (neural retina development) - -AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "The progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-12-21T02:15:14Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003407") -AnnotationAssertion(rdfs:label "neural retina development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cell motility involved in camera-type eye morphogenesis) - -AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another and contributes to the physical shaping or formation of the camera-type eye.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-12-21T03:04:27Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003411") -AnnotationAssertion(rdfs:label "cell motility involved in camera-type eye morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (chondrocyte differentiation involved in endochondral bone morphogenesis) - -AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "The process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte that will contribute to the development of a bone. A chondrocyte is a polymorphic cell that forms cartilage.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-12-22T08:39:58Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003413") -AnnotationAssertion(rdfs:label "chondrocyte differentiation involved in endochondral bone morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (chondrocyte morphogenesis involved in endochondral bone morphogenesis) - -AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "The process in which the structures of a chondrocyte that will contribute to bone development are generated and organized.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-12-22T08:42:55Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003414") -AnnotationAssertion(rdfs:label "chondrocyte morphogenesis involved in endochondral bone morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (chondrocyte hypertrophy) AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "The growth of a chondrocyte, where growth contributes to the progression of the chondrocyte over time.") @@ -52632,133 +20673,6 @@ AnnotationAssertion(rdfs:label "chon SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (endochondral bone growth) - -AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "The increase in size or mass of an endochondral bone that contributes to the shaping of the bone.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-12-22T08:52:55Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003416") -AnnotationAssertion(rdfs:label "endochondral bone growth") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (growth plate cartilage development) - -AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "The process whose specific outcome is the progression of the cartilage that will provide a scaffold for mineralization of endochondral bones as they elongate or grow.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-12-22T08:57:42Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003417") -AnnotationAssertion(rdfs:label "growth plate cartilage development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (growth plate cartilage chondrocyte differentiation) - -AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "The process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte that will contribute to the growth of a bone. A chondrocyte is a polymorphic cell that forms cartilage.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-12-22T09:00:56Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003418") -AnnotationAssertion(rdfs:label "growth plate cartilage chondrocyte differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (growth plate cartilage morphogenesis) - -AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "The process in which the anatomical structures of growth plate cartilage are generated and organized.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-12-22T09:21:30Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003422") -AnnotationAssertion(rdfs:label "growth plate cartilage morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (growth plate cartilage chondrocyte morphogenesis) - -AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "The process in which the structures of a chondrocyte in the growth plate cartilage are generated and organized.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-12-22T12:22:24Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003429") -AnnotationAssertion(rdfs:label "growth plate cartilage chondrocyte morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (growth plate cartilage chondrocyte growth) - -AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "The growth of a growth plate cartilage chondrocyte, where growth contributes to the progression of the chondrocyte over time from one condition to another.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-12-22T12:29:19Z") -AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "growth plate cartilage chondrocyte hypertrophy") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003430") -AnnotationAssertion(rdfs:label "growth plate cartilage chondrocyte growth") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (growth plate cartilage chondrocyte development) - -AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "The progression of a growth plate cartilage chondrocyte over time from after its fate commitment to the mature cell.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-12-22T12:32:49Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003431") -AnnotationAssertion(rdfs:label "growth plate cartilage chondrocyte development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cell growth involved in growth plate cartilage chondrocyte morphogenesis) - -AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "The growth of a growth plate cartilage chondrocyte, where growth contributes to the shaping of the chondrocyte over time.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-12-22T12:37:48Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003432") -AnnotationAssertion(rdfs:label "cell growth involved in growth plate cartilage chondrocyte morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (chondrocyte development involved in endochondral bone morphogenesis) - -AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "The progression of a chondrocyte over time from after its commitment to its mature state where the chondrocyte will contribute to the shaping of an endochondral bone.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-12-22T12:42:44Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003433") -AnnotationAssertion(rdfs:label "chondrocyte development involved in endochondral bone morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (regulation of cell adhesion involved in growth plate cartilage morphogenesis) - -AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the frequency, rate or extent of attachment of a cell to another cell or to the extracellular matrix and contributes to the shaping of the growth plate cartilage of an endochondral bone.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-12-22T01:28:15Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003436") -AnnotationAssertion(rdfs:label "regulation of cell adhesion involved in growth plate cartilage morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of cell communication involved in growth plate cartilage morphogenesis) - -AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the frequency, rate or extent of cell communication that contributes to the shaping of the growth plate cartilage.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-12-22T01:34:24Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0003437") -AnnotationAssertion(rdfs:label "regulation of cell communication involved in growth plate cartilage morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (molecular_function) AnnotationAssertion(Annotation( "GOC:pdt") "A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs.") @@ -52778,98 +20692,6 @@ SubClassOf( ) DisjointClasses( ) -# Class: (nucleic acid binding) - -AnnotationAssertion(Annotation( "GOC:jl") "Binding to a nucleic acid.") -AnnotationAssertion( "GO:0000496") -AnnotationAssertion( "base pairing") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0003676") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "nucleic acid binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (DNA binding) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:jl") Annotation( "GOC:tb") Annotation( "GOC:vw") "Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).") -AnnotationAssertion( "GO:0043566") -AnnotationAssertion( "plasmid binding") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "microtubule/chromatin interaction") -AnnotationAssertion( "structure specific DNA binding") -AnnotationAssertion( "structure-specific DNA binding") -AnnotationAssertion( "GO:0003677") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "DNA binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (chromatin binding) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0198506732") Annotation( "PMID:20404130") "Binding to chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.") -AnnotationAssertion( "lamin/chromatin binding") -AnnotationAssertion( "microtubule/chromatin interaction") -AnnotationAssertion( "nuclear membrane vesicle binding to chromatin") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0003682") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "chromatin binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (nuclear steroid receptor activity) - -AnnotationAssertion(Annotation( "GOC:signaling") Annotation( "PMID:14708019") "Combining with a steroid hormone and transmitting the signal within the cell to initiate a change in cell activity or function.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/16717"^^xsd:anyURI) -AnnotationAssertion( "steroid hormone receptor activity") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0003707") -AnnotationAssertion(rdfs:label "nuclear steroid receptor activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (RNA binding) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "GOC:mah") "Binding to an RNA molecule or a portion thereof.") -AnnotationAssertion( "GO:0000498") -AnnotationAssertion( "GO:0044822") -AnnotationAssertion(Annotation(rdfs:label "Exportin-5 recognizes 3' overhang of pre-miRNA") "Reactome:R-HSA-203922") -AnnotationAssertion( "base pairing with RNA") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "poly(A) RNA binding") -AnnotationAssertion( "poly(A)-RNA binding") -AnnotationAssertion( "poly-A RNA binding") -AnnotationAssertion( "GO:0003723") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "RNA binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - # Class: (catalytic activity) AnnotationAssertion(Annotation( "GOC:vw") Annotation( "ISBN:0198506732") "Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.") @@ -52887,1139 +20709,6 @@ AnnotationAssertion( "catalytic activity") SubClassOf( ) -# Class: (nuclease activity) - -AnnotationAssertion(Annotation( "ISBN:0198547684") "Catalysis of the hydrolysis of ester linkages within nucleic acids.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0004518") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "Note that 'tRNA nucleotidyltransferase activity ; GO:0009022', also known as 'ribonuclease PH', and 'DNA-(apurinic or apyrimidinic site) lyase activity ; GO:0003906' do not have parentage in the 'nuclease activity' branch of the ontology because both GO and the Enzyme Commission define nuclease activity as a type of hydrolysis.") -AnnotationAssertion(rdfs:label "nuclease activity") -SubClassOf( ) - -# Class: (DNA nuclease activity) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "ISBN:0198547684") "Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid.") -AnnotationAssertion( "GO:0004537") -AnnotationAssertion(Annotation(rdfs:label "Cleavage of DNA by DFF40") "Reactome:R-HSA-211247") -AnnotationAssertion(Annotation(rdfs:label "Long-range resection of DNA DSBs by EXO1 or DNA2") "Reactome:R-HSA-5685994") -AnnotationAssertion(Annotation(rdfs:label "DNA nucleases unhook the interstrand crosslink (ICL)") "Reactome:R-HSA-6785986") -AnnotationAssertion( "deoxyribonuclease activity") -AnnotationAssertion( "caspase-activated deoxyribonuclease activity") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0004536") -AnnotationAssertion(rdfs:label "DNA nuclease activity") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (protein kinase activity) - -AnnotationAssertion(Annotation( "PMID:25399640") "Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP.") -AnnotationAssertion( "GO:0050222") -AnnotationAssertion(Annotation(rdfs:label "INF-gamma induced phosphorylation of L13a") "Reactome:R-HSA-156832") -AnnotationAssertion(Annotation(rdfs:label "IRAK1 phosphorylates Pellino") "Reactome:R-HSA-937034") -AnnotationAssertion(Annotation(rdfs:label "Unknown kinase phosphorylates NICD4") "Reactome:R-HSA-9604606") -AnnotationAssertion(Annotation(rdfs:label "GTP-bound RAC1 contributes to MAPK8 activation") "Reactome:R-HSA-9673284") -AnnotationAssertion(Annotation(rdfs:label "IRAK1 phosphorylates Pellino upon TLR7/8 or 9 activation") "Reactome:R-HSA-975139") -AnnotationAssertion( "protamine kinase activity") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0004672") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "Note that triphosphate is used as a phosphate donor by at least one kinase.") -AnnotationAssertion(rdfs:label "protein kinase activity") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (protein tyrosine kinase activity) - -AnnotationAssertion(Annotation( "RHEA:10596") "Catalysis of the reaction: ATP + a protein tyrosine = ADP + protein tyrosine phosphate.") -AnnotationAssertion( "GO:0004718") -AnnotationAssertion(Annotation( "skos:narrowMatch") "EC:2.7.10.2") -AnnotationAssertion(Annotation( "skos:exactMatch") "RHEA:10596") -AnnotationAssertion(Annotation(rdfs:label "SRC autophosphorylation is positively regulated by InlA-bound CDH1") "Reactome:R-HSA-112333") -AnnotationAssertion(Annotation(rdfs:label "Fyn/Lyn-mediated phosphorylation of FcR1 gamma") "Reactome:R-HSA-114600") -AnnotationAssertion(Annotation(rdfs:label "STAT5 tyrosine phosphorylation") "Reactome:R-HSA-1168394") -AnnotationAssertion(Annotation(rdfs:label "Trans-autophosphorylation of activated ligand-responsive EGFR mutant dimers") "Reactome:R-HSA-1169421") -AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of SHC1 by ligand-responsive p-6Y-EGFR mutants") "Reactome:R-HSA-1225952") -AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of CBL by ligand-responsive p-6Y-EGFR mutants") "Reactome:R-HSA-1225960") -AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of PLCG1 by ligand-responsive p-6Y-EGFR mutants") "Reactome:R-HSA-1247844") -AnnotationAssertion(Annotation(rdfs:label "Trans-autophosphorylation of EGFRvIII mutant dimers") "Reactome:R-HSA-1248655") -AnnotationAssertion(Annotation(rdfs:label "Trans-autophosphorylation of ERBB2 homodimer") "Reactome:R-HSA-1248694") -AnnotationAssertion(Annotation(rdfs:label "SHC1 phosphorylation by ERBB2 heterodimers") "Reactome:R-HSA-1250195") -AnnotationAssertion(Annotation(rdfs:label "Trans-autophosphorylation of ERBB4 homodimers") "Reactome:R-HSA-1250315") -AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of SHC1 by ERBB4 homodimers") "Reactome:R-HSA-1250348") -AnnotationAssertion(Annotation(rdfs:label "PLCG1 phosphorylation by p-EGFR:p-ERBB2") "Reactome:R-HSA-1251922") -AnnotationAssertion(Annotation(rdfs:label "IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3:STAT5A,STAT5B phosphorylates STAT5") "Reactome:R-HSA-1295540") -AnnotationAssertion(Annotation(rdfs:label "SRC phosphorylates SPRY2 on Y55 and Y227") "Reactome:R-HSA-1295609") -AnnotationAssertion(Annotation(rdfs:label "Autocatalytic phosphorylation of BetaKlotho-bound FGFR4") "Reactome:R-HSA-1307963") -AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of JAK2") "Reactome:R-HSA-1433418") -AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of GAB2 by SFKs") "Reactome:R-HSA-1433454") -AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of SHP2 by SFKs") "Reactome:R-HSA-1433488") -AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of APS") "Reactome:R-HSA-1433506") -AnnotationAssertion(Annotation(rdfs:label "Phosphorylation and activation of VAV1") "Reactome:R-HSA-1433542") -AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of STATs") "Reactome:R-HSA-1470009") -AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of p-KIT on Y900 by Src kinases") "Reactome:R-HSA-1472121") -AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of PLCgamma by PDGFR") "Reactome:R-HSA-1524186") -AnnotationAssertion(Annotation(rdfs:label "PRLR-bound STAT5 is phosphorylated") "Reactome:R-HSA-1671691") -AnnotationAssertion(Annotation(rdfs:label "Wee1-mediated phosphorylation of Cyclin B1:phospho-Cdc2 complexes") "Reactome:R-HSA-170070") -AnnotationAssertion(Annotation(rdfs:label "Wee1-mediated phosphorylation of Cyclin A:phospho-Cdc2 complexes") "Reactome:R-HSA-170156") -AnnotationAssertion(Annotation(rdfs:label "SRC-1 autophosphorylates") "Reactome:R-HSA-170991") -AnnotationAssertion(Annotation(rdfs:label "Binding and activation of MAP Kinase") "Reactome:R-HSA-171011") -AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of Cyclin A:Cdk2 at Tyr 15") "Reactome:R-HSA-174164") -AnnotationAssertion(Annotation(rdfs:label "GAB1 phosphorylation by EGFR kinase") "Reactome:R-HSA-177930") -AnnotationAssertion(Annotation(rdfs:label "EGFR autophosphorylation") "Reactome:R-HSA-177934") -AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of EGFR by SRC kinase") "Reactome:R-HSA-177937") -AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of CBL (EGFR:CBL)") "Reactome:R-HSA-182969") -AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of CBL (EGFR:GRB2:CBL)") "Reactome:R-HSA-183058") -AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of cytosolic FGFR1 fusion dimers") "Reactome:R-HSA-1839065") -AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of BCR moiety of BCR-FGFR1") "Reactome:R-HSA-1839067") -AnnotationAssertion(Annotation(rdfs:label "Activated FGFR1 mutants and fusions phosphorylate PLCG1") "Reactome:R-HSA-1839098") -AnnotationAssertion(Annotation(rdfs:label "p-BCR-p-FGFR1 phosphorylates GAB2") "Reactome:R-HSA-1839110") -AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of STAT5 by cytosolic FGFR1 fusions") "Reactome:R-HSA-1839112") -AnnotationAssertion(Annotation(rdfs:label "Autophosphorylation of PDGF beta receptors") "Reactome:R-HSA-186786") -AnnotationAssertion(Annotation(rdfs:label "FGFR1OP-FGFR1 phosphorylates STAT1 and STAT3") "Reactome:R-HSA-1888198") -AnnotationAssertion(Annotation(rdfs:label "Autocatalytic phosphorylation of FGFR4") "Reactome:R-HSA-190326") -AnnotationAssertion(Annotation(rdfs:label "Autocatalytic phosphorylation of FGFR3b") "Reactome:R-HSA-190385") -AnnotationAssertion(Annotation(rdfs:label "Autocatalytic phosphorylation of FGFR3c") "Reactome:R-HSA-190388") -AnnotationAssertion(Annotation(rdfs:label "Autocatalytic phosphorylation of FGFR2b") "Reactome:R-HSA-190408") -AnnotationAssertion(Annotation(rdfs:label "Autocatalytic phosphorylation of FGFR2c") "Reactome:R-HSA-190413") -AnnotationAssertion(Annotation(rdfs:label "Autocatalytic phosphorylation of FGFR1b") "Reactome:R-HSA-190427") -AnnotationAssertion(Annotation(rdfs:label "Autocatalytic phosphorylation of FGFR1c") "Reactome:R-HSA-190429") -AnnotationAssertion(Annotation(rdfs:label "Autocatalytic phosphorylation of Klotho-bound FGFR1c") "Reactome:R-HSA-191062") -AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of Cx43 by c-src") "Reactome:R-HSA-191636") -AnnotationAssertion(Annotation(rdfs:label "Trans-autophosphorylation of p-Y877-ERBB2 heterodimers") "Reactome:R-HSA-1963581") -AnnotationAssertion(Annotation(rdfs:label "Trans-autophosphorylation of ERBB2 heterodimers") "Reactome:R-HSA-1963582") -AnnotationAssertion(Annotation(rdfs:label "SRC family kinases phosphorylate ERBB2") "Reactome:R-HSA-1963586") -AnnotationAssertion(Annotation(rdfs:label "Ligand-independent phosphorylation of overexpressed FGFR1") "Reactome:R-HSA-1982066") -AnnotationAssertion(Annotation(rdfs:label "Autocatalytic phosphorylation of FGFR3c P250R mutant") "Reactome:R-HSA-2012073") -AnnotationAssertion(Annotation(rdfs:label "Autocatalytic phosphorylation of FGFR3 cysteine mutants") "Reactome:R-HSA-2012082") -AnnotationAssertion(Annotation(rdfs:label "Autocatalytic phosphorylation of FGFR4 Y367C mutant") "Reactome:R-HSA-2012087") -AnnotationAssertion(Annotation(rdfs:label "ALK autophosphorylation downstream of PTN and MDK") "Reactome:R-HSA-201521") -AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of ITAM motifs in CD3 complexes") "Reactome:R-HSA-202165") -AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of ZAP-70 by Lck") "Reactome:R-HSA-202168") -AnnotationAssertion(Annotation(rdfs:label "Activation of ZAP-70") "Reactome:R-HSA-202174") -AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of SLP-76") "Reactome:R-HSA-202216") -AnnotationAssertion(Annotation(rdfs:label "Inactivation of Lck by Csk") "Reactome:R-HSA-202233") -AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of TBSMs in LAT") "Reactome:R-HSA-202245") -AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of PLC-gamma1") "Reactome:R-HSA-202248") -AnnotationAssertion(Annotation(rdfs:label "Activation of Lck") "Reactome:R-HSA-202291") -AnnotationAssertion(Annotation(rdfs:label "Change of PKC theta conformation") "Reactome:R-HSA-202307") -AnnotationAssertion(Annotation(rdfs:label "Autocatalytic phosphorylation of FGFR1c P252X mutant dimers") "Reactome:R-HSA-2023455") -AnnotationAssertion(Annotation(rdfs:label "Autocatalytic phosphorylation of FGFR1 mutants with enhanced kinase activity") "Reactome:R-HSA-2023460") -AnnotationAssertion(Annotation(rdfs:label "Phosphorylation and activation of PLCG") "Reactome:R-HSA-2029268") -AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of SYK by Src kinases") "Reactome:R-HSA-2029449") -AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of VAV") "Reactome:R-HSA-2029453") -AnnotationAssertion(Annotation(rdfs:label "Sequestering and phosphorylation Fc gamma receptors in the lipid rafts") "Reactome:R-HSA-2029459") -AnnotationAssertion(Annotation(rdfs:label "Autocatalytic phosphorylation of FGFR2 ligand-independent mutants") "Reactome:R-HSA-2029984") -AnnotationAssertion(Annotation(rdfs:label "Autocatalytic phosphorylation of overexpressed FGFR2 variants") "Reactome:R-HSA-2029989") -AnnotationAssertion(Annotation(rdfs:label "Autocatalytic phosphorylation of FGFR3 point mutants with enhanced kinase activity") "Reactome:R-HSA-2033485") -AnnotationAssertion(Annotation(rdfs:label "Autocatalytic phosphorylation of FGFR2c mutants with enhanced ligand binding") "Reactome:R-HSA-2033486") -AnnotationAssertion(Annotation(rdfs:label "Autocatalytic phosphorylation of FGFR2b mutants with enhanced ligand binding") "Reactome:R-HSA-2033488") -AnnotationAssertion(Annotation(rdfs:label "Autocatalytic phosphorylation of FGFR2 point mutants with enhanced kinase activity") "Reactome:R-HSA-2033490") -AnnotationAssertion(Annotation(rdfs:label "Autocatalytic phosphorylation of FGFR3 t(4;14) translocation mutants") "Reactome:R-HSA-2038387") -AnnotationAssertion(Annotation(rdfs:label "Autocatalytic phosphorylation of FGFR4 mutants with enhanced kinase activity") "Reactome:R-HSA-2038944") -AnnotationAssertion(Annotation(rdfs:label "Autophosphorylation of KIT") "Reactome:R-HSA-205289") -AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of PECAM-1 by Fyn or Lyn or c-Src") "Reactome:R-HSA-210291") -AnnotationAssertion(Annotation(rdfs:label "Trans-phosphorylation of Tie2") "Reactome:R-HSA-210872") -AnnotationAssertion(Annotation(rdfs:label "EGFR activates PLC-gamma1 by phosphorylation") "Reactome:R-HSA-212710") -AnnotationAssertion(Annotation(rdfs:label "ABL phosphorylates WAVEs") "Reactome:R-HSA-2130194") -AnnotationAssertion(Annotation(rdfs:label "Src phosphorylate WASP,N-WASP") "Reactome:R-HSA-2197698") -AnnotationAssertion(Annotation(rdfs:label "TIRAP is phosphorylated by BTK") "Reactome:R-HSA-2201322") -AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of SYK") "Reactome:R-HSA-2395412") -AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of DAP12") "Reactome:R-HSA-2395439") -AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of LAT by p-SYK") "Reactome:R-HSA-2395801") -AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of SLP-76 by p-SYK") "Reactome:R-HSA-2396594") -AnnotationAssertion(Annotation(rdfs:label "IGF1R phosphorylates SHC1") "Reactome:R-HSA-2404193") -AnnotationAssertion(Annotation(rdfs:label "IGF1,2:IGF1R autophosphorylates") "Reactome:R-HSA-2404199") -AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of BTK by p-SYK") "Reactome:R-HSA-2424484") -AnnotationAssertion(Annotation(rdfs:label "Phosphorylation and activation of VAV2/VAV3 by SYK") "Reactome:R-HSA-2424486") -AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of PLC-gamma by p-BTK/p-SYK") "Reactome:R-HSA-2424487") -AnnotationAssertion(Annotation(rdfs:label "IGF1,2:p-Y1161,1165,1166-IGF1R phosphorylates IRS1,2,4") "Reactome:R-HSA-2428926") -AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of beta and gamma subunits by LYN") "Reactome:R-HSA-2454208") -AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of SYK") "Reactome:R-HSA-2454239") -AnnotationAssertion(Annotation(rdfs:label "JAK2 Phosphorylates LEPR") "Reactome:R-HSA-2586553") -AnnotationAssertion(Annotation(rdfs:label "JAK2 Autophosphorylates in Response to Leptin") "Reactome:R-HSA-2586555") -AnnotationAssertion(Annotation(rdfs:label "JAK2 Phosphorylates SHP2 (PTPN11) in Response to Leptin") "Reactome:R-HSA-2671742") -AnnotationAssertion(Annotation(rdfs:label "JAK2 Phosphorylates STAT5 in Response to Leptin") "Reactome:R-HSA-2671829") -AnnotationAssertion(Annotation(rdfs:label "JAK2 Phosphoryates STAT3 in Response to Leptin") "Reactome:R-HSA-2671850") -AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of TEC kinases by p-SYK") "Reactome:R-HSA-2730833") -AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of LAT by p-SYK") "Reactome:R-HSA-2730843") -AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of SLP-76 by p-SYK") "Reactome:R-HSA-2730851") -AnnotationAssertion(Annotation(rdfs:label "Autophosphorylation of BTK/ITK") "Reactome:R-HSA-2730858") -AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of GAB2 by SYK/FYN") "Reactome:R-HSA-2730860") -AnnotationAssertion(Annotation(rdfs:label "Autophosphorylation of LYN kinase") "Reactome:R-HSA-2730862") -AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of PKC-theta") "Reactome:R-HSA-2730882") -AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of NTAL by p-SYK/Lyn") "Reactome:R-HSA-2730884") -AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of SHC by SYK kinase") "Reactome:R-HSA-2730886") -AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of PLC-gamma") "Reactome:R-HSA-2730888") -AnnotationAssertion(Annotation(rdfs:label "PRMT5 is tyrosine phosphorylated by JAK2 V617F") "Reactome:R-HSA-3215391") -AnnotationAssertion(Annotation(rdfs:label "Autophosphorylation of PTK2 at Y397") "Reactome:R-HSA-354073") -AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of pPTK2 by SRC") "Reactome:R-HSA-354124") -AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of BCAR1 by SRC-PTK2 complex") "Reactome:R-HSA-372693") -AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of nephrin by FYN") "Reactome:R-HSA-373747") -AnnotationAssertion(Annotation(rdfs:label "SEMA4D interacts with Plexin-B1:ErbB2") "Reactome:R-HSA-373750") -AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of DCC by Fyn") "Reactome:R-HSA-374701") -AnnotationAssertion(Annotation(rdfs:label "Autophosphorylation of SRC") "Reactome:R-HSA-377640") -AnnotationAssertion(Annotation(rdfs:label "Activation of Src") "Reactome:R-HSA-380780") -AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of CD28") "Reactome:R-HSA-388831") -AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of CTLA-4") "Reactome:R-HSA-388833") -AnnotationAssertion(Annotation(rdfs:label "Autophosphorylation of PDGF alpha receptors") "Reactome:R-HSA-389083") -AnnotationAssertion(Annotation(rdfs:label "Autophosphorylation of PDGF alpha/beta receptors") "Reactome:R-HSA-389086") -AnnotationAssertion(Annotation(rdfs:label "CSF1R trans-autophosphorylates on multiple tyrosine and serine residues") "Reactome:R-HSA-389159") -AnnotationAssertion(Annotation(rdfs:label "Activation of Vav1") "Reactome:R-HSA-389354") -AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of PD-1") "Reactome:R-HSA-389762") -AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of ITIM motif in SIRP alpha") "Reactome:R-HSA-391156") -AnnotationAssertion(Annotation(rdfs:label "Recruitment of FAK to NCAM1:Fyn in lipid rafts") "Reactome:R-HSA-391865") -AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of FAK by Src kinase") "Reactome:R-HSA-391866") -AnnotationAssertion(Annotation(rdfs:label "Autophosphorylation of NCAM1 bound Fyn") "Reactome:R-HSA-391871") -AnnotationAssertion(Annotation(rdfs:label "EPH receptors autophosphorylate") "Reactome:R-HSA-3928578") -AnnotationAssertion(Annotation(rdfs:label "SFKs phosphorylate EFNBs") "Reactome:R-HSA-3928580") -AnnotationAssertion(Annotation(rdfs:label "FYN phosphorylates NMDAR2B") "Reactome:R-HSA-3928583") -AnnotationAssertion(Annotation(rdfs:label "SFKs phosphorylate GIT1") "Reactome:R-HSA-3928594") -AnnotationAssertion(Annotation(rdfs:label "SFKs phosphorylate VAV2,3") "Reactome:R-HSA-3928604") -AnnotationAssertion(Annotation(rdfs:label "PTK2 autophosphorylates at Y397") "Reactome:R-HSA-3928610") -AnnotationAssertion(Annotation(rdfs:label "EPHB phosphorylates TIAM1") "Reactome:R-HSA-3928627") -AnnotationAssertion(Annotation(rdfs:label "SFKs phosphorylate NGEF") "Reactome:R-HSA-3928648") -AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of Plexin-A") "Reactome:R-HSA-399934") -AnnotationAssertion(Annotation(rdfs:label "Recruitment and activation of Cdk5") "Reactome:R-HSA-399946") -AnnotationAssertion(Annotation(rdfs:label "Tyrosine phosphorylation of CRMPs by Fes") "Reactome:R-HSA-399947") -AnnotationAssertion(Annotation(rdfs:label "p-EPHB phosphorylates SDC2") "Reactome:R-HSA-4093332") -AnnotationAssertion(Annotation(rdfs:label "Activated SRC-1 activates MAPKs (in F2R:ARRB1:MAPKs:active SRC-1)") "Reactome:R-HSA-418163") -AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of Unc5C") "Reactome:R-HSA-418859") -AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of FADK1") "Reactome:R-HSA-418872") -AnnotationAssertion(Annotation(rdfs:label "SEMA4D interacts with Plexin-B1:Met") "Reactome:R-HSA-419646") -AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of ROBO1 by ABL kinase") "Reactome:R-HSA-428888") -AnnotationAssertion(Annotation(rdfs:label "SYK activation by SRC") "Reactome:R-HSA-429441") -AnnotationAssertion(Annotation(rdfs:label "Syk activation leads to SLP-76 activation") "Reactome:R-HSA-429449") -AnnotationAssertion(Annotation(rdfs:label "FGR binds and phosphorylates LRP8") "Reactome:R-HSA-432129") -AnnotationAssertion(Annotation(rdfs:label "Syk/Lck phosphorylate LAT") "Reactome:R-HSA-434836") -AnnotationAssertion(Annotation(rdfs:label "VEGFR2 autophosphorylates") "Reactome:R-HSA-4420117") -AnnotationAssertion(Annotation(rdfs:label "SFKs phosphorylate PLCG1") "Reactome:R-HSA-4420121") -AnnotationAssertion(Annotation(rdfs:label "SRC-1 phosphorylates SHB") "Reactome:R-HSA-4420128") -AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of SRC-1") "Reactome:R-HSA-4420206") -AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of L1 by EPHB2") "Reactome:R-HSA-443817") -AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of Y1229 in L1") "Reactome:R-HSA-445076") -AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of L1 by SRC") "Reactome:R-HSA-445084") -AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of VAV2") "Reactome:R-HSA-445085") -AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of Neurofascin") "Reactome:R-HSA-445091") -AnnotationAssertion(Annotation(rdfs:label "Within the IL-2R complex JAK3 phosphorylates JAK1") "Reactome:R-HSA-451942") -AnnotationAssertion(Annotation(rdfs:label "Recruited STAT5 is phosphorylated") "Reactome:R-HSA-452097") -AnnotationAssertion(Annotation(rdfs:label "SHC1 bound to IL2 receptor is phosphorylated") "Reactome:R-HSA-452100") -AnnotationAssertion(Annotation(rdfs:label "JAK1 phosphorylates Y338, Y392 and Y510 of IL2RB") "Reactome:R-HSA-452122") -AnnotationAssertion(Annotation(rdfs:label "SYK is a substrate for JAK1") "Reactome:R-HSA-508282") -AnnotationAssertion(Annotation(rdfs:label "SRC-1 phosphorylates p-Y397-PTK2") "Reactome:R-HSA-5218640") -AnnotationAssertion(Annotation(rdfs:label "PTK2 autophosphorylates") "Reactome:R-HSA-5218642") -AnnotationAssertion(Annotation(rdfs:label "FYN autophosphorylates") "Reactome:R-HSA-5218806") -AnnotationAssertion(Annotation(rdfs:label "PTK2 and SRC-1 phosphorylate PXN on Y31 and Y118") "Reactome:R-HSA-5218809") -AnnotationAssertion(Annotation(rdfs:label "FYN phosphorylates PAK2") "Reactome:R-HSA-5218812") -AnnotationAssertion(Annotation(rdfs:label "Src kinases phosphorylate VAV") "Reactome:R-HSA-5218820") -AnnotationAssertion(Annotation(rdfs:label "PTK2/SRC-1 phosphorylates BCAR1") "Reactome:R-HSA-5218828") -AnnotationAssertion(Annotation(rdfs:label "SRC-1 phosphorylates PTK2-beta") "Reactome:R-HSA-5218830") -AnnotationAssertion(Annotation(rdfs:label "p-Y402-PTK2B phosphorylates p-5Y,S732-PTK2 on Y407") "Reactome:R-HSA-5218851") -AnnotationAssertion(Annotation(rdfs:label "AXL autophosphorylates on Y772 and Y814") "Reactome:R-HSA-5357429") -AnnotationAssertion(Annotation(rdfs:label "1,3-beta-D-glucan:p-Y15-CLEC7A:SYK phosphorylates PLCG") "Reactome:R-HSA-5607745") -AnnotationAssertion(Annotation(rdfs:label "SRC kinase phosphorylates CLEC7A:1,3-beta-D-glucan") "Reactome:R-HSA-5607750") -AnnotationAssertion(Annotation(rdfs:label "LYN and FYN phosphorylate FCER1G in CLEC6A:FCERG and CLEC4E:FCERG") "Reactome:R-HSA-5621355") -AnnotationAssertion(Annotation(rdfs:label "SYK phosphorylates PLCG2 in p-6Y-SYK:p-Y65,Y76-FCER1G:PLCG2") "Reactome:R-HSA-5621363") -AnnotationAssertion(Annotation(rdfs:label "SYK autophosphorylates") "Reactome:R-HSA-5621370") -AnnotationAssertion(Annotation(rdfs:label "SFKs phosphorylates RAF1 on Y340,Y341") "Reactome:R-HSA-5624486") -AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of PLC-gamma 1 by p-EGFRvIII mutant") "Reactome:R-HSA-5637795") -AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of SHC1 by p-5Y-EGFRvIII") "Reactome:R-HSA-5637796") -AnnotationAssertion(Annotation(rdfs:label "Activated FGFR2 phosphorylates PLCG1") "Reactome:R-HSA-5654147") -AnnotationAssertion(Annotation(rdfs:label "Activated FGFR1 phosphorylates PLCG1") "Reactome:R-HSA-5654149") -AnnotationAssertion(Annotation(rdfs:label "Activated FGFR4 phosphorylates PLCG1") "Reactome:R-HSA-5654151") -AnnotationAssertion(Annotation(rdfs:label "Activated FGFR3 phosphorylates PLCG1") "Reactome:R-HSA-5654222") -AnnotationAssertion(Annotation(rdfs:label "Activated FGFR2 phosphorylates FRS2") "Reactome:R-HSA-5654397") -AnnotationAssertion(Annotation(rdfs:label "Activated FGFR2 phosphorylates SHC1") "Reactome:R-HSA-5654407") -AnnotationAssertion(Annotation(rdfs:label "Activated FGFR3 phosphorylates FRS2") "Reactome:R-HSA-5654408") -AnnotationAssertion(Annotation(rdfs:label "Activated FGFR4 phosphorylates FRS2") "Reactome:R-HSA-5654418") -AnnotationAssertion(Annotation(rdfs:label "Activated FGFR4 phosphorylates SHC1") "Reactome:R-HSA-5654428") -AnnotationAssertion(Annotation(rdfs:label "Ligand-independent phosphorylation of overexpressed FGFR1c") "Reactome:R-HSA-5654545") -AnnotationAssertion(Annotation(rdfs:label "Activated FGFR1 phosphorylates FRS2") "Reactome:R-HSA-5654575") -AnnotationAssertion(Annotation(rdfs:label "Activated FGFR1 phosphorylates FRS3") "Reactome:R-HSA-5654578") -AnnotationAssertion(Annotation(rdfs:label "Activated FGFR1 phosphorylates SHC1") "Reactome:R-HSA-5654582") -AnnotationAssertion(Annotation(rdfs:label "Activated FGFR1:p-FRS phosphorylates PPTN11") "Reactome:R-HSA-5654587") -AnnotationAssertion(Annotation(rdfs:label "Activated FGFR2 phosphorylates FRS3") "Reactome:R-HSA-5654605") -AnnotationAssertion(Annotation(rdfs:label "Activated FGFR2 phosphorylates PPTN11") "Reactome:R-HSA-5654607") -AnnotationAssertion(Annotation(rdfs:label "Activated FGFR3 phosphorylates FRS3") "Reactome:R-HSA-5654628") -AnnotationAssertion(Annotation(rdfs:label "Activated FGFR3 phosphorylates PPTN11") "Reactome:R-HSA-5654631") -AnnotationAssertion(Annotation(rdfs:label "Activated FGFR3 phosphorylates SHC1") "Reactome:R-HSA-5654634") -AnnotationAssertion(Annotation(rdfs:label "Activated FGFR4 phosphorylates FRS3") "Reactome:R-HSA-5654653") -AnnotationAssertion(Annotation(rdfs:label "Activated FGFR4 phosphorylates PPTN11") "Reactome:R-HSA-5654655") -AnnotationAssertion(Annotation(rdfs:label "Activated FGFR3 point and translocation mutants phosphorylate PLCG1") "Reactome:R-HSA-5655243") -AnnotationAssertion(Annotation(rdfs:label "Activated FGFR2 mutants phosphorylate FRS2") "Reactome:R-HSA-5655268") -AnnotationAssertion(Annotation(rdfs:label "Activated FGFR3 point, translocation and fusion mutants phosphorylate FRS2") "Reactome:R-HSA-5655270") -AnnotationAssertion(Annotation(rdfs:label "Activated FGFR1 mutants phosphorylate FRS2") "Reactome:R-HSA-5655278") -AnnotationAssertion(Annotation(rdfs:label "Activated FGFR4 mutants phosphorylate FRS2") "Reactome:R-HSA-5655284") -AnnotationAssertion(Annotation(rdfs:label "Activated FGFR2 mutants phosphorylate PLCG1") "Reactome:R-HSA-5655301") -AnnotationAssertion(Annotation(rdfs:label "Activated FGFR4 mutants phosphorylate PLCG1") "Reactome:R-HSA-5655341") -AnnotationAssertion(Annotation(rdfs:label "WICH phosphorylates H2AFX on Y142") "Reactome:R-HSA-5683930") -AnnotationAssertion(Annotation(rdfs:label "ABL1 phosphorylates RAD52") "Reactome:R-HSA-5686587") -AnnotationAssertion(Annotation(rdfs:label "LYN phosphorylates CD22") "Reactome:R-HSA-5690702") -AnnotationAssertion(Annotation(rdfs:label "STAT3 is phosphorylated by p-Y-JAK1,P-Y-TYK2") "Reactome:R-HSA-6784006") -AnnotationAssertion(Annotation(rdfs:label "JAK1,TYK2 phosphorylate JAK1,TYK2") "Reactome:R-HSA-6784319") -AnnotationAssertion(Annotation(rdfs:label "HVEM induses BTLA phosphorylation") "Reactome:R-HSA-6790087") -AnnotationAssertion(Annotation(rdfs:label "MET dimers autophosphorylate") "Reactome:R-HSA-6806974") -AnnotationAssertion(Annotation(rdfs:label "Mcm2-7 is phosphorylated by DDK") "Reactome:R-HSA-68954") -AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of Cyclin E:CDK2 complexes by WEE1") "Reactome:R-HSA-69195") -AnnotationAssertion(Annotation(rdfs:label "Transphosphorylation of JAK1") "Reactome:R-HSA-873918") -AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of JAK2") "Reactome:R-HSA-873919") -AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of STAT1 by JAK kinases") "Reactome:R-HSA-873922") -AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of IFNGR1 by JAK kinases") "Reactome:R-HSA-873924") -AnnotationAssertion(Annotation(rdfs:label "Tyrosine kinases phosphorylate the receptor") "Reactome:R-HSA-879907") -AnnotationAssertion(Annotation(rdfs:label "Activation of STAT5a/b by JAK2") "Reactome:R-HSA-879909") -AnnotationAssertion(Annotation(rdfs:label "SHC1 bound to the common beta chain becomes tyrosine phosphorylated") "Reactome:R-HSA-879925") -AnnotationAssertion(Annotation(rdfs:label "FRK phosphorylates PTEN") "Reactome:R-HSA-8847977") -AnnotationAssertion(Annotation(rdfs:label "ERBB2 promotes PTK6 autophosphorylation") "Reactome:R-HSA-8848005") -AnnotationAssertion(Annotation(rdfs:label "PTK6 phosphorylates STAP2") "Reactome:R-HSA-8848077") -AnnotationAssertion(Annotation(rdfs:label "PTK6 phosphorylates STAT3") "Reactome:R-HSA-8848124") -AnnotationAssertion(Annotation(rdfs:label "PTK6 phosphorylates CDKN1B") "Reactome:R-HSA-8848436") -AnnotationAssertion(Annotation(rdfs:label "PTK6 phosphorylates PXN") "Reactome:R-HSA-8848606") -AnnotationAssertion(Annotation(rdfs:label "PTK6 phosphorylates BCAR1") "Reactome:R-HSA-8848726") -AnnotationAssertion(Annotation(rdfs:label "PTK6 phosphorylates AKT1") "Reactome:R-HSA-8848758") -AnnotationAssertion(Annotation(rdfs:label "PTK6 phosphorylates DOK1") "Reactome:R-HSA-8848776") -AnnotationAssertion(Annotation(rdfs:label "PTK6 phosphorylates CBL") "Reactome:R-HSA-8848818") -AnnotationAssertion(Annotation(rdfs:label "PTK6 phosphorylates ARAP1") "Reactome:R-HSA-8848873") -AnnotationAssertion(Annotation(rdfs:label "PTK6 phosphorylates KHDRBS1") "Reactome:R-HSA-8848975") -AnnotationAssertion(Annotation(rdfs:label "PTK6 phosphorylates KHDRBS2") "Reactome:R-HSA-8849032") -AnnotationAssertion(Annotation(rdfs:label "PTK6 phosphorylates KHDRBS3") "Reactome:R-HSA-8849042") -AnnotationAssertion(Annotation(rdfs:label "PTK6 phosphorylates ARHGAP35") "Reactome:R-HSA-8849068") -AnnotationAssertion(Annotation(rdfs:label "SRMS phosphorylates PTK6") "Reactome:R-HSA-8849102") -AnnotationAssertion(Annotation(rdfs:label "PTK6 phosphorylates SFPQ") "Reactome:R-HSA-8849463") -AnnotationAssertion(Annotation(rdfs:label "MET phosphorylates SHC1-2") "Reactome:R-HSA-8851890") -AnnotationAssertion(Annotation(rdfs:label "MET phosphorylates GAB1") "Reactome:R-HSA-8851933") -AnnotationAssertion(Annotation(rdfs:label "Autocatalytic phosphorylation of FGFR3 fusions") "Reactome:R-HSA-8853309") -AnnotationAssertion(Annotation(rdfs:label "FGFR2 fusions autophosphorylate") "Reactome:R-HSA-8853313") -AnnotationAssertion(Annotation(rdfs:label "Plasma membrane FGFR1 fusions autophosphorylate") "Reactome:R-HSA-8853325") -AnnotationAssertion(Annotation(rdfs:label "FYN phosphorylates DAB1 in RELN:VLDLR:DAB1:SH3KBP1") "Reactome:R-HSA-8855237") -AnnotationAssertion(Annotation(rdfs:label "EGFR phosphorylates GPNMB") "Reactome:R-HSA-8857555") -AnnotationAssertion(Annotation(rdfs:label "LINC01139 facilitates PTK6 autophosphorylation") "Reactome:R-HSA-8857577") -AnnotationAssertion(Annotation(rdfs:label "LINC01139 promotes phosphorylation of HIF1A by PTK6") "Reactome:R-HSA-8857583") -AnnotationAssertion(Annotation(rdfs:label "Inhibition of PP2A activity by phosphorylation of the catalytic subunit at tyrosine Y307") "Reactome:R-HSA-8857925") -AnnotationAssertion(Annotation(rdfs:label "EGFR phosphorylates EPS15") "Reactome:R-HSA-8867041") -AnnotationAssertion(Annotation(rdfs:label "PTK2 autophosphorylates") "Reactome:R-HSA-8874078") -AnnotationAssertion(Annotation(rdfs:label "SRC phosphorylates PTK2") "Reactome:R-HSA-8874080") -AnnotationAssertion(Annotation(rdfs:label "MET phosphorylates PTK2") "Reactome:R-HSA-8874082") -AnnotationAssertion(Annotation(rdfs:label "MET phosphorylates CBL") "Reactome:R-HSA-8875451") -AnnotationAssertion(Annotation(rdfs:label "MET phosphorylates STAT3") "Reactome:R-HSA-8875817") -AnnotationAssertion(Annotation(rdfs:label "InlB:MET dimer trans-autophophorylates") "Reactome:R-HSA-8876230") -AnnotationAssertion(Annotation(rdfs:label "InlB-activated MET phosphorylates CBL") "Reactome:R-HSA-8876246") -AnnotationAssertion(Annotation(rdfs:label "SRC phosphorylates InlA-bound CDH1 and CTNNB1") "Reactome:R-HSA-8876948") -AnnotationAssertion(Annotation(rdfs:label "SRC phosphorylates RUNX1") "Reactome:R-HSA-8937728") -AnnotationAssertion(Annotation(rdfs:label "SRC phosphorylates RUNX3") "Reactome:R-HSA-8937807") -AnnotationAssertion(Annotation(rdfs:label "SRC,YES1 phosphorylate YAP1") "Reactome:R-HSA-8937844") -AnnotationAssertion(Annotation(rdfs:label "Tyrosine kinases phosphorylate Cip/Kip inhibitors bound to CDK4/6:CCND complexes") "Reactome:R-HSA-8942607") -AnnotationAssertion(Annotation(rdfs:label "p-S13, FUNDC1 is phosphorylated by CK2 at Tyr18") "Reactome:R-HSA-8948143") -AnnotationAssertion(Annotation(rdfs:label "ABL1 phosphorylates YAP1") "Reactome:R-HSA-8956659") -AnnotationAssertion(Annotation(rdfs:label "G protein alpha (i)-SRC complex catalyzes SRC to p-Y416-SRC") "Reactome:R-HSA-8964242") -AnnotationAssertion(Annotation(rdfs:label "G alpha (s):GTP:SRC catalyzes SRC to p-Y416-SRC") "Reactome:R-HSA-8964252") -AnnotationAssertion(Annotation(rdfs:label "JAK2 bound to IL12RB2:IL12RB2 phosphorylate STAT4") "Reactome:R-HSA-8983872") -AnnotationAssertion(Annotation(rdfs:label "Phospho-JAK2 phosphorylates EPOR") "Reactome:R-HSA-9006323") -AnnotationAssertion(Annotation(rdfs:label "JAK2 transphosphorylates and is activated in response to Erythropoietin") "Reactome:R-HSA-9006332") -AnnotationAssertion(Annotation(rdfs:label "SRC phosphorylates ROBO3.1 in response to NTN1") "Reactome:R-HSA-9011241") -AnnotationAssertion(Annotation(rdfs:label "JAK2 and LYN phosphorylate STAT5 in EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2") "Reactome:R-HSA-9012650") -AnnotationAssertion(Annotation(rdfs:label "EGFR phosphorylates NOTCH3") "Reactome:R-HSA-9018572") -AnnotationAssertion(Annotation(rdfs:label "ESR-associated SRC autophosphorylates") "Reactome:R-HSA-9021609") -AnnotationAssertion(Annotation(rdfs:label "LYN phosphorylates CRKL in EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2:CRKL:RAPGEF1") "Reactome:R-HSA-9024726") -AnnotationAssertion(Annotation(rdfs:label "BDNF-bound NTRK2 dimers trans-autophosphorylate") "Reactome:R-HSA-9026464") -AnnotationAssertion(Annotation(rdfs:label "NTF3-bound NTRK2 dimers trans-autophosphorylate") "Reactome:R-HSA-9026502") -AnnotationAssertion(Annotation(rdfs:label "NTF4-bound NTRK2 dimers trans-autophosphorylate") "Reactome:R-HSA-9026510") -AnnotationAssertion(Annotation(rdfs:label "NTRK2 phosphorylates PLCG1") "Reactome:R-HSA-9026579") -AnnotationAssertion(Annotation(rdfs:label "NTRK2 phosphorylates SHC1") "Reactome:R-HSA-9026890") -AnnotationAssertion(Annotation(rdfs:label "EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2 phosphorylates IRS2") "Reactome:R-HSA-9027272") -AnnotationAssertion(Annotation(rdfs:label "JAK2 phosphorylates GAB1 in EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2:GAB1") "Reactome:R-HSA-9027273") -AnnotationAssertion(Annotation(rdfs:label "LYN phosphorylates PLCG1,2 in EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2:PLCG1,2") "Reactome:R-HSA-9027425") -AnnotationAssertion(Annotation(rdfs:label "NTRK2 phosphorylates FRS2") "Reactome:R-HSA-9028728") -AnnotationAssertion(Annotation(rdfs:label "JAK2 phosphorylates VAV1 in EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2:p-Y-CRKL:RASGEF1:p-Y-SHC1:GRB2:VAV1") "Reactome:R-HSA-9029151") -AnnotationAssertion(Annotation(rdfs:label "JAK2 phosphorylates SHC1 in EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:p-CRKL:RABGEF1:SHC1") "Reactome:R-HSA-9029155") -AnnotationAssertion(Annotation(rdfs:label "NTRK2 phosphorylates FRS3") "Reactome:R-HSA-9032426") -AnnotationAssertion(Annotation(rdfs:label "NTRK2-bound FYN autophosphorylates") "Reactome:R-HSA-9032532") -AnnotationAssertion(Annotation(rdfs:label "FYN-mediated phosphorylation of GRIN2B") "Reactome:R-HSA-9032601") -AnnotationAssertion(Annotation(rdfs:label "NTRK2 phosphorylates CDK5") "Reactome:R-HSA-9032854") -AnnotationAssertion(Annotation(rdfs:label "NTRK2 promotes TIAM1 phosphorylation") "Reactome:R-HSA-9033284") -AnnotationAssertion(Annotation(rdfs:label "NTRK3 dimers trans-autophosphorylate") "Reactome:R-HSA-9034714") -AnnotationAssertion(Annotation(rdfs:label "NTRK3 phosphorylates PLCG1") "Reactome:R-HSA-9034814") -AnnotationAssertion(Annotation(rdfs:label "NTRK3 phosphorylates SHC1") "Reactome:R-HSA-9034875") -AnnotationAssertion(Annotation(rdfs:label "SRC,FYN phosphorylate NTRK2") "Reactome:R-HSA-9037040") -AnnotationAssertion(Annotation(rdfs:label "Formation of p-STAT1 homodimer") "Reactome:R-HSA-909718") -AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of STAT1") "Reactome:R-HSA-909726") -AnnotationAssertion(Annotation(rdfs:label "Activation of JAK kinases") "Reactome:R-HSA-909729") -AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of INFAR1 by TYK2") "Reactome:R-HSA-909730") -AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of STAT2") "Reactome:R-HSA-909732") -AnnotationAssertion(Annotation(rdfs:label "CBL is tyrosine phosphorylated") "Reactome:R-HSA-912629") -AnnotationAssertion(Annotation(rdfs:label "Activated NTRK3 promotes SRC autophosphorylation") "Reactome:R-HSA-9603420") -AnnotationAssertion(Annotation(rdfs:label "FLT3LG dimer:FLT3 dimer autophosphorylates") "Reactome:R-HSA-9604767") -AnnotationAssertion(Annotation(rdfs:label "BTK autophosphorylates") "Reactome:R-HSA-9606159") -AnnotationAssertion(Annotation(rdfs:label "Phosphorylated BTK phosphorylates PLCG2") "Reactome:R-HSA-9606162") -AnnotationAssertion(Annotation(rdfs:label "p-SYK and LYN phosphorylate BTK") "Reactome:R-HSA-9606163") -AnnotationAssertion(Annotation(rdfs:label "SRC phosphorylates GluN2 (GRIN2) subunits of NMDARs") "Reactome:R-HSA-9612085") -AnnotationAssertion(Annotation(rdfs:label "NTRK1,2 in ADCYAP1(2-742):ADCYAP1R1:NTRK1,2 autophosphorylates") "Reactome:R-HSA-9612996") -AnnotationAssertion(Annotation(rdfs:label "NTRK1,2 in Ade-Rib:ADORA2A:NTRK1,2 autophosphorylates") "Reactome:R-HSA-9613023") -AnnotationAssertion(Annotation(rdfs:label "SHC1 is phosphorylated downstream of estrogen stimulation of GPER1") "Reactome:R-HSA-9624014") -AnnotationAssertion(Annotation(rdfs:label "PTK2 autophosphorylates downstream of EGFR") "Reactome:R-HSA-9625487") -AnnotationAssertion(Annotation(rdfs:label "ERBB2 homodimer phosphorylates SHC1") "Reactome:R-HSA-9634390") -AnnotationAssertion(Annotation(rdfs:label "Src phosphorylate SYK in IgG:Leishmania surface:p-FCGR3A:SYK") "Reactome:R-HSA-9664261") -AnnotationAssertion(Annotation(rdfs:label "Src phosphorylates CD3 dimers in IgG:Lma antigens:FCGR3A:CD3 dimers") "Reactome:R-HSA-9664275") -AnnotationAssertion(Annotation(rdfs:label "Phosphorylation and activation of PLCG due to FCGR3A effect") "Reactome:R-HSA-9664278") -AnnotationAssertion(Annotation(rdfs:label "ERBB2 KD mutants trans-autophosphorylate") "Reactome:R-HSA-9664588") -AnnotationAssertion(Annotation(rdfs:label "Phosphorylated heterodimers of ERBB2 KD mutants phosphorylate SHC1") "Reactome:R-HSA-9664976") -AnnotationAssertion(Annotation(rdfs:label "Phosphorylated heterodimers of ERBB2 KD mutants and EGFR phosphorylate PLCG1") "Reactome:R-HSA-9665032") -AnnotationAssertion(Annotation(rdfs:label "Heterodimers of ERBB2 ECD mutants and EGFR trans-autophosphorylate") "Reactome:R-HSA-9665389") -AnnotationAssertion(Annotation(rdfs:label "Phosphorylated heterodimers of ERBB2 ECD mutants and EGFR phosphorylate PLCG1") "Reactome:R-HSA-9665411") -AnnotationAssertion(Annotation(rdfs:label "Phosphorylated heterodimers of ERBB2 TMD/JMD mutants and EGFR phosphorylate PLCG1") "Reactome:R-HSA-9665704") -AnnotationAssertion(Annotation(rdfs:label "Phosphorylated heterodimers of ERBB2 TMD/JMD mutants phosphorylate SHC1") "Reactome:R-HSA-9665705") -AnnotationAssertion(Annotation(rdfs:label "ERBB2 TMD/JMD heterodimers trans-autophosphorylate") "Reactome:R-HSA-9665709") -AnnotationAssertion(Annotation(rdfs:label "p-6Y-SYK phosphorylates VAV1,2,3") "Reactome:R-HSA-9666425") -AnnotationAssertion(Annotation(rdfs:label "Constitutive phosphorylation of kinase domain KIT mutants") "Reactome:R-HSA-9669890") -AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of juxtamembrane domain KIT mutants") "Reactome:R-HSA-9669911") -AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of STATs downstream of KIT mutants") "Reactome:R-HSA-9670412") -AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of JAK2 downstream of KIT mutants") "Reactome:R-HSA-9670418") -AnnotationAssertion(Annotation(rdfs:label "Autophosphorylation of PDGFRA extracellular domain dimers") "Reactome:R-HSA-9672173") -AnnotationAssertion(Annotation(rdfs:label "Autophosphorylation of PDGFR mutant dimers") "Reactome:R-HSA-9672175") -AnnotationAssertion(Annotation(rdfs:label "Autophosphorylation of cytosolic PDGFRA and PDGFRB fusion proteins") "Reactome:R-HSA-9673756") -AnnotationAssertion(Annotation(rdfs:label "Autophosphorylation of membrane-tethered fusions of PDGFRA or PDGFRB") "Reactome:R-HSA-9673761") -AnnotationAssertion(Annotation(rdfs:label "p-Y-JAK1 phosphorylates CSF3R in CSF3 dimer:2xCSF3R:LYN:p-Y-JAK1") "Reactome:R-HSA-9674558") -AnnotationAssertion(Annotation(rdfs:label "p-Y-JAK1,2 phosphorylates STAT1,3,5 in CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-Y-JAK2:p-TYK2") "Reactome:R-HSA-9674567") -AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of extracellular domain KIT mutants") "Reactome:R-HSA-9680248") -AnnotationAssertion(Annotation(rdfs:label "Constitutive phosphorylation of FLT3 mutants") "Reactome:R-HSA-9695834") -AnnotationAssertion(Annotation(rdfs:label "FLT3 mutants phosphorylate GAB2") "Reactome:R-HSA-9698003") -AnnotationAssertion(Annotation(rdfs:label "FLT3 ITD mutants phosphorylate STAT5") "Reactome:R-HSA-9698005") -AnnotationAssertion(Annotation(rdfs:label "Active FLT3 phosphorylates CDKN1B") "Reactome:R-HSA-9699578") -AnnotationAssertion(Annotation(rdfs:label "Active ALK phosphorylates FRS2") "Reactome:R-HSA-9700164") -AnnotationAssertion(Annotation(rdfs:label "Active ALK phosphorylates IRS1") "Reactome:R-HSA-9700168") -AnnotationAssertion(Annotation(rdfs:label "Active ALK phosphorylates PLCG1") "Reactome:R-HSA-9700171") -AnnotationAssertion(Annotation(rdfs:label "Active ALK phosphorylates SHC1") "Reactome:R-HSA-9700175") -AnnotationAssertion(Annotation(rdfs:label "Autophosphorylation of ALK fusions") "Reactome:R-HSA-9700181") -AnnotationAssertion(Annotation(rdfs:label "Autophosphorylation of point mutants of ALK") "Reactome:R-HSA-9700186") -AnnotationAssertion(Annotation(rdfs:label "ALK mutants phosphorylate SHC1") "Reactome:R-HSA-9700193") -AnnotationAssertion(Annotation(rdfs:label "Active ALK phosphorylates SRC") "Reactome:R-HSA-9700647") -AnnotationAssertion(Annotation(rdfs:label "Active ALK phosphorylates JAK3") "Reactome:R-HSA-9701488") -AnnotationAssertion(Annotation(rdfs:label "FLT3 fusion dimers autophosphorylate") "Reactome:R-HSA-9703437") -AnnotationAssertion(Annotation(rdfs:label "FLT3 fusions phosphorylate GAB2") "Reactome:R-HSA-9703438") -AnnotationAssertion(Annotation(rdfs:label "FLT3 phosphorylates GRB10") "Reactome:R-HSA-9706344") -AnnotationAssertion(Annotation(rdfs:label "FLT3 phosphorylates CBL") "Reactome:R-HSA-9706350") -AnnotationAssertion(Annotation(rdfs:label "PTK6 phosphorylates STAT3") "Reactome:R-HSA-9709918") -AnnotationAssertion(Annotation(rdfs:label "ALK fusions phosphorylate IRS1") "Reactome:R-HSA-9712082") -AnnotationAssertion(Annotation(rdfs:label "ALK mutants phosphorylate STAT3") "Reactome:R-HSA-9712085") -AnnotationAssertion(Annotation(rdfs:label "ALK fusions phosphorylate PLCG1") "Reactome:R-HSA-9712086") -AnnotationAssertion(Annotation(rdfs:label "ALK fusions phosphorylate FRS") "Reactome:R-HSA-9712087") -AnnotationAssertion(Annotation(rdfs:label "SRC phosphorylates RHOU") "Reactome:R-HSA-9726848") -AnnotationAssertion(Annotation(rdfs:label "CSF1R trans-autophosphorylates on tyrosine-561") "Reactome:R-HSA-9733314") -AnnotationAssertion(Annotation(rdfs:label "Src family kinases phosphorylate CBL in CSF1 dimer:p-Y561-CSF1R dimer:CBL") "Reactome:R-HSA-9733323") -AnnotationAssertion(Annotation(rdfs:label "BACH1 is phosphorylated at tyrosine 486") "Reactome:R-HSA-9762209") -AnnotationAssertion(Annotation(rdfs:label "JAK2 phosphorylation of GHR") "Reactome:R-HSA-982807") -AnnotationAssertion(Annotation(rdfs:label "p-6Y-SYK phosphorylates BLNK (SLP65)") "Reactome:R-HSA-983703") -AnnotationAssertion(Annotation(rdfs:label "SYK autophosphorylates at the activated BCR") "Reactome:R-HSA-983707") -AnnotationAssertion(Annotation(rdfs:label "LYN, FYN, BLK phosphorylate ITAMs of Ig-alpha (CD79A) and Ig-beta (CD79B)") "Reactome:R-HSA-983709") -AnnotationAssertion( "protein-tyrosine kinase activity") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0004713") -AnnotationAssertion(rdfs:label "protein tyrosine kinase activity") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (transmembrane receptor protein tyrosine kinase activity) - -AnnotationAssertion(Annotation( "EC:2.7.10.1") Annotation( "GOC:mah") "Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-tyrosine = ADP + a protein-L-tyrosine phosphate.") -AnnotationAssertion(Annotation( "skos:exactMatch") "EC:2.7.10.1") -AnnotationAssertion( "MetaCyc:2.7.10.1-RXN") -AnnotationAssertion(Annotation(rdfs:label "TrkA receptor autophosphorylates") "Reactome:R-HSA-166544") -AnnotationAssertion(Annotation(rdfs:label "SHC, complexed with TrkA, is tyrosine-phosphorylated") "Reactome:R-HSA-167019") -AnnotationAssertion(Annotation(rdfs:label "TrkA phosphorylates PLCG1") "Reactome:R-HSA-167683") -AnnotationAssertion(Annotation(rdfs:label "ARMS is phosphorylated by active TrkA receptor") "Reactome:R-HSA-169905") -AnnotationAssertion(Annotation(rdfs:label "SHC1 phosphorylation by phosphorylated EGFR") "Reactome:R-HSA-177933") -AnnotationAssertion(Annotation(rdfs:label "TRKA phosphorylates IRS") "Reactome:R-HSA-198295") -AnnotationAssertion(Annotation(rdfs:label "p-Y-JAK1,p-Y-TYK2 phosphorylate IL10RA") "Reactome:R-HSA-6784324") -AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of IRS") "Reactome:R-HSA-74711") -AnnotationAssertion(Annotation(rdfs:label "Phosphorylation of SHC1") "Reactome:R-HSA-74742") -AnnotationAssertion(Annotation(rdfs:label "MST1R autophosphorylates") "Reactome:R-HSA-8852552") -AnnotationAssertion(Annotation(rdfs:label "RET tyrosine phosphorylation") "Reactome:R-HSA-8853792") -AnnotationAssertion(Annotation(rdfs:label "STAT3, STAT4 are phosphorylated by p-JAK2, p-TYK2 in IL23:IL23 receptor") "Reactome:R-HSA-8950269") -AnnotationAssertion(Annotation(rdfs:label "IL27RA and IL6ST are phosphorylated after IL27:IL27 receptor interaction and JAK's phosphorylation") "Reactome:R-HSA-8950340") -AnnotationAssertion(Annotation(rdfs:label "STAT4 is phosphorylated by p-JAK2 and/or p-Y-TYK2 after IL12:IL12R interaction") "Reactome:R-HSA-8950354") -AnnotationAssertion(Annotation(rdfs:label "IL23R in IL23:IL23 receptor complex is phosphorylated") "Reactome:R-HSA-8950364") -AnnotationAssertion(Annotation(rdfs:label "JAK1/JAK2 bound to IL35:IL6ST:IL12RB2 receptor are phosphorylated") "Reactome:R-HSA-8950405") -AnnotationAssertion(Annotation(rdfs:label "JAK2, TYK2 in IL12A:IL12RB1:TYK2:IL12B:IL12RB2:JAK2 are phosphorylated") "Reactome:R-HSA-8950423") -AnnotationAssertion(Annotation(rdfs:label "JAK1/JAK2 bound to IL12RB2:IL6ST receptor phosphorylates STAT1 and STAT4") "Reactome:R-HSA-8950453") -AnnotationAssertion(Annotation(rdfs:label "STAT3 and STAT1 are phosphorylated by JAKs after IL27:IL27R interaction") "Reactome:R-HSA-8950485") -AnnotationAssertion(Annotation(rdfs:label "JAK1, JAK2, TYK2 in IL27:EBI3:IL27RA:JAK1:IL6ST:(JAK1,JAK2,TYK2) are phosphorylated") "Reactome:R-HSA-8950537") -AnnotationAssertion(Annotation(rdfs:label "JAK2, TYK2 in IL23A:IL12B:IL23R:JAK2:IL12RB1:TYK2 are phosphorylated") "Reactome:R-HSA-8950591") -AnnotationAssertion(Annotation(rdfs:label "IL12RB2 in IL12A:IL12RB1:p-Y-TYK2:IL12B:IL12RB2:p-JAK2 is phosphorylated") "Reactome:R-HSA-8950757") -AnnotationAssertion(Annotation(rdfs:label "IL19:IL20RA:p-JAK1:IL20RB:STAT3 phosphorylates STAT3") "Reactome:R-HSA-8982163") -AnnotationAssertion(Annotation(rdfs:label "IL15RA:IL15:IL2RB:JAK1:IL2RG:JAK3 phosphorylates JAK3 and JAK1") "Reactome:R-HSA-8983300") -AnnotationAssertion(Annotation(rdfs:label "IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 phosphorylates SHC1") "Reactome:R-HSA-8983309") -AnnotationAssertion(Annotation(rdfs:label "IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 phosphorylates STAT3 and STAT5") "Reactome:R-HSA-8983371") -AnnotationAssertion(Annotation(rdfs:label "IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3:p-Y-SHC1:GRB2:GAB2 phosphorylates GAB2") "Reactome:R-HSA-8983424") -AnnotationAssertion(Annotation(rdfs:label "IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:STAT1 phosphorylates STAT1, STAT2, STAT3, STAT4 and STAT5") "Reactome:R-HSA-8986985") -AnnotationAssertion(Annotation(rdfs:label "IL26:IL20RA:JAK1:IL10RB:TYK2 phosphorylates JAK1, TYK2") "Reactome:R-HSA-8986994") -AnnotationAssertion(Annotation(rdfs:label "IL22:IL22RA1:p-JAK1:IL10RB:p-TYK2 phosphorylates IL22RA") "Reactome:R-HSA-8986995") -AnnotationAssertion(Annotation(rdfs:label "IL24:IL22RA1:JAK1:IL20RB phosphorylates JAK1") "Reactome:R-HSA-8987012") -AnnotationAssertion(Annotation(rdfs:label "IFNL1:IFNLR1:p-JAK1:IL10RB:p-TYK2 phosphorylates IFNLR1") "Reactome:R-HSA-8987040") -AnnotationAssertion(Annotation(rdfs:label "IL22:IL22RA1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2") "Reactome:R-HSA-8987042") -AnnotationAssertion(Annotation(rdfs:label "IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2:STAT3 phosphorylates STAT3") "Reactome:R-HSA-8987070") -AnnotationAssertion(Annotation(rdfs:label "IL19:IL20RA:JAK1:IL20RB phosphorylates JAK1") "Reactome:R-HSA-8987084") -AnnotationAssertion(Annotation(rdfs:label "IL24:IL22RA1:p-JAK1:IL20RB:STAT3 phosphorylates STAT3") "Reactome:R-HSA-8987096") -AnnotationAssertion(Annotation(rdfs:label "JAK1 in IL24:IL20RA:JAK1:IL20RB is phosphorylated") "Reactome:R-HSA-8987129") -AnnotationAssertion(Annotation(rdfs:label "IL20:IL20RA:JAK1:IL20RB:p-JAK3,p-JAK2:STAT3 phosphorylates STAT3") "Reactome:R-HSA-8987141") -AnnotationAssertion(Annotation(rdfs:label "IL24:IL20RA:p-JAK1:IL20RB:STAT1,STAT3 phosphorylates STAT1 or STAT3") "Reactome:R-HSA-8987150") -AnnotationAssertion(Annotation(rdfs:label "IL20:IL20RA:JAK1:IL20RB:JAK2,JAK3 phosphorylates JAK2,JAK3") "Reactome:R-HSA-8987179") -AnnotationAssertion(Annotation(rdfs:label "IFNL1:IFNLR1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2") "Reactome:R-HSA-8987202") -AnnotationAssertion(Annotation(rdfs:label "IL26:IL10RB:p-TYK2:IL20RA:p-JAK1:STAT1,STAT3 phosphorylates STAT1,STAT3") "Reactome:R-HSA-8987255") -AnnotationAssertion( "molecular_function") -AnnotationAssertion(Annotation( "EC:2.7.10.1") "receptor protein tyrosine kinase activity") -AnnotationAssertion(Annotation( "EC:2.7.10.1") "receptor protein-tyrosine kinase activity") -AnnotationAssertion( "GO:0004714") -AnnotationAssertion(rdfs:label "transmembrane receptor protein tyrosine kinase activity") -SubClassOf( ) -SubClassOf( ) - -# Class: (nuclear glucocorticoid receptor activity) - -AnnotationAssertion(Annotation( "GOC:signaling") Annotation( "PMID:17689856") Annotation( "PMID:20920967") "Combining with a glucocorticoid and transmitting the signal within the cell trigger a change in cell activity or function.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/16717"^^xsd:anyURI) -AnnotationAssertion( "glucocorticoid receptor activity") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0004883") -AnnotationAssertion(rdfs:label "nuclear glucocorticoid receptor activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (transmembrane signaling receptor activity) - -AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "Wikipedia:Transmembrane_receptor") "Combining with an extracellular or intracellular signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity or state as part of signal transduction.") -AnnotationAssertion( "GO:0004926") -AnnotationAssertion( "GO:0099600") -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:signaling") "transmembrane receptor activity") -AnnotationAssertion(Annotation(rdfs:label "Sphingomyelinase is activated by the NGF:p75NTR complex") "Reactome:R-HSA-193672") -AnnotationAssertion(Annotation( "GOC:mah") "transmembrane signalling receptor activity") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0004888") -AnnotationAssertion(rdfs:comment "This term includes intracellular membrane receptors, e.g. IP3 triggered release of Ca2+ from intracellular stores.") -AnnotationAssertion(rdfs:label "transmembrane signaling receptor activity") -SubClassOf( ) - -# Class: (cytokine receptor activity) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:mah") "Combining with a cytokine and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.") -AnnotationAssertion( "GO:0004907") -AnnotationAssertion( "IL receptor") -AnnotationAssertion(Annotation( "http://wiki.geneontology.org/index.php/Why_isn%27t_interleukin_in_GO%3F") "interleukin receptor activity") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "hematopoietin/interferon-class (D200-domain) cytokine receptor activity") -AnnotationAssertion( "GO:0004896") -AnnotationAssertion(rdfs:label "cytokine receptor activity") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (prolactin receptor activity) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:signaling") "Combining with prolactin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.") -AnnotationAssertion( ) -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0004925") -AnnotationAssertion(rdfs:label "prolactin receptor activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) -DisjointClasses( ObjectSomeValuesFrom( )) - -# Class: (G protein-coupled receptor activity) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "Wikipedia:GPCR") Annotation( "http://www.iuphar-db.org") "Combining with an extracellular signal and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.") -AnnotationAssertion( "GO:0001622") -AnnotationAssertion( "GO:0001623") -AnnotationAssertion( "GO:0001624") -AnnotationAssertion( "GO:0001625") -AnnotationAssertion( "GO:0016526") -AnnotationAssertion(Annotation(rdfs:label "Thrombin-activated PARs activate G12/13") "Reactome:R-HSA-114552") -AnnotationAssertion(Annotation(rdfs:label "Thrombin-activated PARs activate Gq") "Reactome:R-HSA-114558") -AnnotationAssertion(Annotation(rdfs:label "The high affinity receptor complex binds to G-protein") "Reactome:R-HSA-167408") -AnnotationAssertion( "Wikipedia:GPCR") -AnnotationAssertion( "G protein coupled receptor activity") -AnnotationAssertion( "G protein linked receptor activity") -AnnotationAssertion( "G-protein coupled receptor activity") -AnnotationAssertion( "G-protein linked receptor activity") -AnnotationAssertion( "GPCR activity") -AnnotationAssertion( "ligand-dependent GPCR activity") -AnnotationAssertion(Annotation( "GOC:bf") "receptor activity, G-protein coupled") -AnnotationAssertion( "EBV-induced receptor") -AnnotationAssertion( "Epstein-Barr Virus-induced receptor activity") -AnnotationAssertion( "G-protein coupled receptor activity, unknown ligand") -AnnotationAssertion( "Mas proto-oncogene receptor activity") -AnnotationAssertion( "RDC1 receptor activity") -AnnotationAssertion( "SREB receptor") -AnnotationAssertion( "orphan G protein coupled receptor activity") -AnnotationAssertion( "orphan G-protein coupled receptor activity") -AnnotationAssertion( "orphan GPCR activity") -AnnotationAssertion( "super conserved receptor expressed in brain receptor activity") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0004930") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "G protein-coupled receptor activity") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (calcitonin receptor activity) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:signaling") Annotation( "PMID:21649645") "Combining with calcitonin and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0004948") -AnnotationAssertion(rdfs:label "calcitonin receptor activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (glucagon receptor activity) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:signaling") Annotation( "PMID:22438981") "Combining with glucagon and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0004967") -AnnotationAssertion(rdfs:label "glucagon receptor activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (histamine receptor activity) - -AnnotationAssertion(Annotation( "GOC:ai") "Combining with histamine to initiate a change in cell activity. Histamine is a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0004969") -AnnotationAssertion(rdfs:label "histamine receptor activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (melanocortin receptor activity) - -AnnotationAssertion(Annotation( "GOC:ai") "Combining with melanocortin to initiate a change in cell activity.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0004977") -AnnotationAssertion(rdfs:label "melanocortin receptor activity") -SubClassOf( ) - -# Class: (corticotropin receptor activity) - -AnnotationAssertion(Annotation( "GOC:ai") "Combining with corticotropin to initiate a change in cell activity.") -AnnotationAssertion( "ACTH receptor activity") -AnnotationAssertion( "adrenocorticotropic hormone receptor activity") -AnnotationAssertion( "adrenocorticotropin receptor activity") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0004978") -AnnotationAssertion(rdfs:label "corticotropin receptor activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (G protein-coupled serotonin receptor activity) - -AnnotationAssertion(Annotation( "GOC:ai") "Combining with the biogenic amine serotonin and transmitting the signal across the membrane by activating an associated G-protein. Serotonin (5-hydroxytryptamine) is a neurotransmitter and hormone found in vertebrates and invertebrates.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/12942"^^xsd:anyURI) -AnnotationAssertion( "GO:0001585") -AnnotationAssertion( "GO:0016609") -AnnotationAssertion( "Wikipedia:5-HT_receptor") -AnnotationAssertion( "5-HT receptor") -AnnotationAssertion( "5-hydroxytryptamine receptor") -AnnotationAssertion( "G protein coupled serotonin receptor activity") -AnnotationAssertion( "G-protein coupled serotonin receptor activity") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0004993") -AnnotationAssertion(rdfs:label "G protein-coupled serotonin receptor activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (somatostatin receptor activity) - -AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:bf") Annotation( "Wikipedia:Somatostatin") "Combining with somatostatin to initiate a change in cell activity. Somatostatin is a peptide hormone that regulates the endocrine system by signaling via G protein-coupled somatostatin receptors. Somatostatin has two active forms produced by proteolytic cleavage: a 14 amino acid peptide (SST-14) and a 28 amino acid peptide (SST-28).") -AnnotationAssertion(Annotation( "Wikipedia:Somatostatin") "GHIH receptor activity") -AnnotationAssertion(Annotation( "Wikipedia:Somatostatin") "SRIF receptor activity") -AnnotationAssertion(Annotation( "Wikipedia:Somatostatin") "SST receptor activity") -AnnotationAssertion(Annotation( "Wikipedia:Somatostatin") "growth hormone-inhibiting hormone receptor activity") -AnnotationAssertion(Annotation( "Wikipedia:Somatostatin") "somatotrophin release inhibiting factor receptor activity") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0004994") -AnnotationAssertion(rdfs:label "somatostatin receptor activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (vasopressin receptor activity) - -AnnotationAssertion(Annotation( "GOC:ai") "Combining with vasopressin to initiate a change in cell activity.") -AnnotationAssertion( "GO:0016931") -AnnotationAssertion( "vasopressin activated calcium mobilizing receptor activity") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0005000") -AnnotationAssertion(rdfs:label "vasopressin receptor activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (insulin receptor activity) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "Combining with insulin receptor ligand and transmitting the signal across the plasma membrane to initiate a change in cell activity.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/23056"^^xsd:anyURI) -AnnotationAssertion(Annotation(rdfs:label "Autophosphorylation of insulin receptor") "Reactome:R-HSA-74715") -AnnotationAssertion( "insulin-activated receptor activity") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0005009") -AnnotationAssertion(rdfs:label "insulin receptor activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - -# Class: (signaling receptor binding) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:ceb") Annotation( "ISBN:0198506732") "Binding to one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.") -AnnotationAssertion( "receptor binding") -AnnotationAssertion( "Wikipedia:Ligand_(biochemistry)") -AnnotationAssertion( "receptor ligand") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "receptor-associated protein activity") -AnnotationAssertion( "GO:0005102") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "Where appropriate, also consider annotating to 'receptor agonist activity ; GO:0048018'.") -AnnotationAssertion(rdfs:label "signaling receptor binding") -SubClassOf( ) - -# Class: (cytokine receptor binding) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:vw") "Binding to a cytokine receptor.") -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:mah") "hematopoietin/interferon-class (D200-domain) cytokine receptor binding") -AnnotationAssertion( "hematopoietin/interferon-class (D200-domain) cytokine receptor ligand") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0005126") -AnnotationAssertion(rdfs:label "cytokine receptor binding") -SubClassOf( ) - -# Class: (vascular endothelial growth factor receptor binding) - -AnnotationAssertion(Annotation( "GOC:ai") "Binding to a vascular endothelial growth factor receptor.") -AnnotationAssertion( "VEGF receptor binding") -AnnotationAssertion( "VEGFR binding") -AnnotationAssertion( "vascular endothelial growth factor") -AnnotationAssertion( "vascular endothelial growth factor receptor ligand") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0005172") -AnnotationAssertion(rdfs:label "vascular endothelial growth factor receptor binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (stem cell factor receptor binding) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "PMID:10698217") "Binding to a stem cell factor receptor (SCFR), a type III transmembrane kinase receptor.") -AnnotationAssertion( "SCFR binding") -AnnotationAssertion( "KIT binding") -AnnotationAssertion( "SCF") -AnnotationAssertion( "stem cell factor") -AnnotationAssertion( "stem cell factor receptor ligand") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0005173") -AnnotationAssertion(rdfs:label "stem cell factor receptor binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (transporter activity) - -AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:dgf") "Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells.") -AnnotationAssertion( "GO:0005478") -AnnotationAssertion(Annotation(rdfs:label "Virion-associated M2 protein mediated ion infusion") "Reactome:R-HSA-168313") -AnnotationAssertion(Annotation(rdfs:label "SMAD7:SMURF1 complex is exported to the cytosol") "Reactome:R-HSA-178215") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "carrier") -AnnotationAssertion( "GO:0005215") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "Some transporters, such as certain members of the SLC family, are referred to as 'carriers'; however GO uses carrier with a different meaning: a carrier binds to and transports the substance (see GO:0140104 molecular carrier activity), whereas a transporter forms some pore that allows the passing of molecules.") -AnnotationAssertion(rdfs:label "transporter activity") -SubClassOf( ) - -# Class: (amine transmembrane transporter activity) - -AnnotationAssertion(Annotation( "GOC:mtg_transport") Annotation( "ISBN:0198506732") Annotation( "ISBN:0815340729") "Enables the transfer of amines, including polyamines, from one side of a membrane to the other. Amines are organic compounds that are weakly basic in character and contain an amino (-NH2) or substituted amino group.") -AnnotationAssertion( "GO:0005279") -AnnotationAssertion( "amine/amide/polyamine channel activity") -AnnotationAssertion( "amine/polyamine transmembrane transporter activity") -AnnotationAssertion( "amino acid-polyamine transmembrane transporter activity") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0005275") -AnnotationAssertion(rdfs:label "amine transmembrane transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (acetylcholine transmembrane transporter activity) - -AnnotationAssertion(Annotation( "GOC:ai") "Enables the transfer of acetylcholine from one side of a membrane to the other. Acetylcholine is an acetic acid ester of the organic base choline and functions as a neurotransmitter, released at the synapses of parasympathetic nerves and at neuromuscular junctions.") -AnnotationAssertion(Annotation(rdfs:label "Loading of acetylcholine in synaptic vesicles") "Reactome:R-HSA-264615") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0005277") -AnnotationAssertion(rdfs:label "acetylcholine transmembrane transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (dicarboxylic acid transmembrane transporter activity) - -AnnotationAssertion(Annotation( "GOC:ai") "Enables the transfer of dicarboxylic acids from one side of a membrane to the other. A dicarboxylic acid is an organic acid with two COOH groups.") -AnnotationAssertion( "GO:0005312") -AnnotationAssertion( "GO:0015365") -AnnotationAssertion(Annotation(rdfs:label "Sulfate is exported to the cytosol in exchange for dicarboxylate") "Reactome:R-HSA-1614546") -AnnotationAssertion(Annotation(rdfs:label "SLC25A10 mediates exchange of malate and phosphate") "Reactome:R-HSA-372843") -AnnotationAssertion( "dicarboxylate carrier") -AnnotationAssertion( "sodium:dicarboxylate/tricarboxylate symporter activity") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "dicarboxylate (succinate/fumarate/malate) antiporter activity") -AnnotationAssertion( "dicarboxylic acid permease activity") -AnnotationAssertion( "GO:0005310") -AnnotationAssertion(rdfs:label "dicarboxylic acid transmembrane transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (L-glutamate transmembrane transporter activity) - -AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:mtg_transport") Annotation( "ISBN:0815340729") "Enables the transfer of L-glutamate from one side of a membrane to the other. L-glutamate is the anion of 2-aminopentanedioic acid.") -AnnotationAssertion( "L-glutamate transporter activity") -AnnotationAssertion( "glutamate transmembrane transporter activity") -AnnotationAssertion(Annotation( "skos:broadMatch") "RHEA:66336") -AnnotationAssertion(Annotation(rdfs:label "L-Glutamate loading of synaptic vesicle") "Reactome:R-HSA-210444") -AnnotationAssertion(Annotation(rdfs:label "SLC17A6,7,8 exchange cytosolic L-Glu for synaptic vesicle H+") "Reactome:R-HSA-428052") -AnnotationAssertion(Annotation(rdfs:label "Defective SLC17A8 does not exchange cytosolic L-Glu for synaptic vesicle H+") "Reactome:R-HSA-5624256") -AnnotationAssertion( "glutamate/aspartate porter activity") -AnnotationAssertion( "glutamate/aspartate:sodium symporter activity") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0005313") -AnnotationAssertion(rdfs:label "L-glutamate transmembrane transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (lipid transporter activity) - -AnnotationAssertion(Annotation( "GOC:ai") "Enables the directed movement of lipids into, out of or within a cell, or between cells.") -AnnotationAssertion(Annotation(rdfs:label "ABCAs mediate lipid efflux") "Reactome:R-HSA-1369028") -AnnotationAssertion(Annotation(rdfs:label "ABCAs mediate lipid influx") "Reactome:R-HSA-1369052") -AnnotationAssertion(Annotation(rdfs:label "ApoB-48 + 40 triacylglycerol + 60 phospholipid => ApoB-48:TG:PL complex") "Reactome:R-HSA-174786") -AnnotationAssertion(Annotation(rdfs:label "ABCA12 transports lipids from cytosol to extracellular region") "Reactome:R-HSA-5682285") -AnnotationAssertion(Annotation(rdfs:label "Defective ABCA12 does not transport lipids from cytosol to extracellular region") "Reactome:R-HSA-5682311") -AnnotationAssertion(Annotation(rdfs:label "Defective ABCA3 does not transport PC, PG from ER membrane to lamellar body") "Reactome:R-HSA-5683672") -AnnotationAssertion(Annotation(rdfs:label "ABCA3 transports PC, PG from ER membrane to lamellar body") "Reactome:R-HSA-5683714") -AnnotationAssertion(Annotation(rdfs:label "Defective ABCA3 does not transport PC, PG from ER membrane to lamellar body") "Reactome:R-HSA-5688397") -AnnotationAssertion(Annotation(rdfs:label "TRIAP1:PRELID1, PRELID3A transports PA from the outer to the inner mitochondrial membrane") "Reactome:R-HSA-6801250") -AnnotationAssertion(Annotation(rdfs:label "ABCA5 transports CHOL from lysosomal lumen to cytosol") "Reactome:R-HSA-8848053") -AnnotationAssertion(Annotation(rdfs:label "MTTP lipidates APOB-100, forming a pre-VLDL") "Reactome:R-HSA-8866329") -AnnotationAssertion( "lipophorin") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "apolipoprotein") -AnnotationAssertion( "GO:0005319") -AnnotationAssertion(rdfs:label "lipid transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "GO_REF:0000090") ObjectSomeValuesFrom( )) - -# Class: (neurotransmitter transmembrane transporter activity) - -AnnotationAssertion(Annotation( "GOC:ai") Annotation( "ISBN:0198506732") "Enables the directed movement of a neurotransmitter into, out of or within a cell, or between cells. Neurotransmitters are any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell.") -AnnotationAssertion(Annotation(rdfs:label "Uptake of Noradrenaline") "Reactome:R-HSA-374896") -AnnotationAssertion(Annotation(rdfs:label "Noradrenaline clearance from the synaptic cleft") "Reactome:R-HSA-374919") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "neurotransmitter transporter activity") -AnnotationAssertion( "GO:0005326") -AnnotationAssertion(rdfs:label "neurotransmitter transmembrane transporter activity") -SubClassOf(Annotation( "GO_REF:0000090") ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - -# Class: (nucleoside transmembrane transporter activity) - -AnnotationAssertion(Annotation( "GOC:ai") "Enables the transfer of a nucleoside, a nucleobase linked to either beta-D-ribofuranose (ribonucleoside) or 2-deoxy-beta-D-ribofuranose, (a deoxyribonucleotide) from one side of a membrane to the other.") -AnnotationAssertion(Annotation(rdfs:label "Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2") "Reactome:R-HSA-109527") -AnnotationAssertion(Annotation(rdfs:label "Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2") "Reactome:R-HSA-109529") -AnnotationAssertion(Annotation(rdfs:label "Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1") "Reactome:R-HSA-109534") -AnnotationAssertion(Annotation(rdfs:label "Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1") "Reactome:R-HSA-109536") -AnnotationAssertion(Annotation(rdfs:label "Defective SLC29A3 does not transport nucleosides from lysosomal lumen to cytosol") "Reactome:R-HSA-5628807") -AnnotationAssertion(Annotation(rdfs:label "Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4") "Reactome:R-HSA-727740") -AnnotationAssertion(Annotation(rdfs:label "SLC29A3 transports nucleosides from lysosomal lumen to cytosol") "Reactome:R-HSA-727749") -AnnotationAssertion(Annotation(rdfs:label "SLC29A3 transports nucleosides from cytosol to lysosomal lumen") "Reactome:R-HSA-727767") -AnnotationAssertion(Annotation(rdfs:label "Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4") "Reactome:R-HSA-727768") -AnnotationAssertion(Annotation(rdfs:label "SLC29A1,2 transport 6MP from extracellular region to cytosol") "Reactome:R-HSA-9751024") -AnnotationAssertion(Annotation(rdfs:label "SLC29A3 transports RBV,RBV-TP from cytosol to mitochondrial matrix") "Reactome:R-HSA-9754929") -AnnotationAssertion(Annotation(rdfs:label "SLC29A1 transports RBV from extracellular region to cytosol") "Reactome:R-HSA-9755015") -AnnotationAssertion(Annotation(rdfs:label "SLC29A1 transports RBV from cytosol to extracellular region") "Reactome:R-HSA-9755035") -AnnotationAssertion( "intracellular nucleoside transmembrane transporter activity") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0005337") -AnnotationAssertion(rdfs:label "nucleoside transmembrane transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "GO_REF:0000090") ObjectSomeValuesFrom( )) - -# Class: (organic acid transmembrane transporter activity) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "Enables the transfer of organic acids from one side of a membrane to the other. Organic acids are acidic compound containing carbon in covalent linkage.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0005342") -AnnotationAssertion(rdfs:label "organic acid transmembrane transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (purine nucleobase transmembrane transporter activity) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "Enables the transfer of purine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, from one side of a membrane to the other.") -AnnotationAssertion(Annotation( "GOC:go_curators") "purine base transmembrane transporter activity") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "purine transmembrane transporter activity") -AnnotationAssertion( "GO:0005345") -AnnotationAssertion(rdfs:label "purine nucleobase transmembrane transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (purine ribonucleotide transmembrane transporter activity) - -AnnotationAssertion(Annotation( "GOC:ai") "Enables the transfer of a purine ribonucleotide, any compound consisting of a purine ribonucleoside (a purine organic base attached to a ribose sugar) esterified with (ortho)phosphate, from one side of a membrane to the other.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0005346") -AnnotationAssertion(rdfs:label "purine ribonucleotide transmembrane transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (ATP transmembrane transporter activity) - -AnnotationAssertion(Annotation( "GOC:ai") "Enables the transfer of ATP, adenosine triphosphate, from one side of a membrane to the other.") -AnnotationAssertion( "GO:0005348") -AnnotationAssertion(Annotation(rdfs:label "CALHM1:CALHM3 transports ATP from the cytosol to the extracellular region") "Reactome:R-HSA-9717392") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0005347") -AnnotationAssertion(rdfs:label "ATP transmembrane transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (glucose transmembrane transporter activity) - -AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:mtg_transport") Annotation( "ISBN:0815340729") "Enables the transfer of the hexose monosaccharide glucose from one side of a membrane to the other.") -AnnotationAssertion( "GO:0015579") -AnnotationAssertion(Annotation(rdfs:label "Transport of Extracellular Glucose to the Cytosol by GLUT1 and GLUT2") "Reactome:R-HSA-499981") -AnnotationAssertion(Annotation(rdfs:label "SLC2A1 tetramer transports Glc from cytosol to Golgi lumen") "Reactome:R-HSA-5653873") -AnnotationAssertion( "glucose permease activity") -AnnotationAssertion( "lactose/glucose efflux transporter activity") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "galactose/glucose (methylgalactoside) porter activity") -AnnotationAssertion( "GO:0005355") -AnnotationAssertion(rdfs:label "glucose transmembrane transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (water transmembrane transporter activity) - -AnnotationAssertion(Annotation( "GOC:ai") "Enables the transfer of water (H2O) from one side of a membrane to the other.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0005372") -AnnotationAssertion(rdfs:label "water transmembrane transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (iron ion transmembrane transporter activity) - -AnnotationAssertion(Annotation( "GOC:ai") "Enables the transfer of iron (Fe) ions from one side of a membrane to the other.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/17162"^^xsd:anyURI) -AnnotationAssertion( "GO:0005382") -AnnotationAssertion( "GO:0016033") -AnnotationAssertion( "GO:0097689") -AnnotationAssertion(Annotation(rdfs:label "SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol") "Reactome:R-HSA-435349") -AnnotationAssertion(Annotation(rdfs:label "Defective SLC11A2 does not cotransport Fe2+, H+ from extracellular region to cytosol") "Reactome:R-HSA-5623558") -AnnotationAssertion(Annotation(rdfs:label "Defective SLC40A1 does not transport Fe2+ from cytosol to extracellular region") "Reactome:R-HSA-5655733") -AnnotationAssertion(Annotation(rdfs:label "SLC40A1:CP:6Cu2+ transports Fe2+ from cytosol to extracellular region") "Reactome:R-HSA-904830") -AnnotationAssertion(Annotation(rdfs:label "MCOLN1 transports Fe2+ from endosome lumen to cytosol") "Reactome:R-HSA-917936") -AnnotationAssertion( "iron cation channel activity") -AnnotationAssertion( "iron channel activity") -AnnotationAssertion( "iron transporter activity") -AnnotationAssertion( "transmembrane iron ion permease activity") -AnnotationAssertion( "transmembrane iron permease activity") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "multicopper ferroxidase iron transport mediator activity") -AnnotationAssertion( "zinc, iron permease activity") -AnnotationAssertion( "GO:0005381") -AnnotationAssertion(rdfs:comment "An example of this is mouse ferroportin (UniProtKB:Q9JHI9), which transports iron out of the cell.") -AnnotationAssertion(rdfs:label "iron ion transmembrane transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (binding) - -AnnotationAssertion(Annotation( "GOC:ceb") Annotation( "GOC:mah") Annotation( "ISBN:0198506732") "The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.") -AnnotationAssertion( "Wikipedia:Binding_(molecular)") -AnnotationAssertion( "ligand") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0005488") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "Note that this term is in the subset of terms that should not be used for direct, manual gene product annotation. Please choose a more specific child term, or request a new one if no suitable term is available. For ligands that bind to signal transducing receptors, consider the molecular function term 'receptor binding ; GO:0005102' and its children.") -AnnotationAssertion(rdfs:label "binding") -SubClassOf( ) - -# Class: (steroid binding) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0198506732") "Binding to a steroid, any of a large group of substances that have in common a ring system based on 1,2-cyclopentanoperhydrophenanthrene.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0005496") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "steroid binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (juvenile hormone binding) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0198506732") "Binding to a juvenile hormone, a sesquiterpenoid derivative that function to maintain the larval state of insects at molting and that may be required for other processes, e.g. oogenesis.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0005500") -AnnotationAssertion(rdfs:label "juvenile hormone binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (fatty acid binding) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "Binding to a fatty acid, an aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0005504") -AnnotationAssertion(rdfs:label "fatty acid binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (iron ion binding) - -AnnotationAssertion(Annotation( "GOC:ai") "Binding to an iron (Fe) ion.") -AnnotationAssertion( "iron binding") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0005506") -AnnotationAssertion(rdfs:label "iron ion binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (calcium ion binding) - -AnnotationAssertion(Annotation( "GOC:ai") "Binding to a calcium ion (Ca2+).") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "calcium ion storage activity") -AnnotationAssertion( "GO:0005509") -AnnotationAssertion(rdfs:label "calcium ion binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (protein binding) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Binding to a protein.") -AnnotationAssertion( "GO:0001948") -AnnotationAssertion( "GO:0045308") -AnnotationAssertion( "protein amino acid binding") -AnnotationAssertion( "glycoprotein binding") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0005515") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "protein binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (collagen binding) - -AnnotationAssertion(Annotation( "GOC:ai") Annotation( "ISBN:0198506732") "Binding to collagen, a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%).") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0005518") -AnnotationAssertion(rdfs:label "collagen binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (ATP binding) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.") -AnnotationAssertion(Annotation(rdfs:label "KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel") "Reactome:R-HSA-265682") -AnnotationAssertion( "Mg-ATP binding") -AnnotationAssertion( "MgATP binding") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0005524") -AnnotationAssertion(rdfs:label "ATP binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (glucose binding) - -AnnotationAssertion(Annotation( "GOC:jl") "Binding to D- or L-enantiomers of glucose.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0005536") -AnnotationAssertion(rdfs:label "glucose binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (glycosaminoglycan binding) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0198506732") "Binding to a glycan (polysaccharide) containing a substantial proportion of aminomonosaccharide residues.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0005539") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "glycosaminoglycan binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (hyaluronic acid binding) - -AnnotationAssertion(Annotation( "GOC:jl") "Binding to hyaluronic acid, a polymer composed of repeating dimeric units of glucuronic acid and N-acetyl glucosamine.") -AnnotationAssertion( "hyaluronan binding") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0005540") -AnnotationAssertion(rdfs:label "hyaluronic acid binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (phospholipid binding) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "Binding to a phospholipid, a class of lipids containing phosphoric acid as a mono- or diester.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0005543") -AnnotationAssertion(rdfs:label "phospholipid binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (phospholipid transporter activity) - -AnnotationAssertion(Annotation( "GOC:ai") Annotation( "ISBN:0198506732") "Enables the directed movement of phospholipids into, out of or within a cell, or between cells. Phospholipids are a class of lipids containing phosphoric acid as a mono- or diester.") -AnnotationAssertion( "GO:0008497") -AnnotationAssertion(Annotation(rdfs:label "4xPALM-C-p-2S-ABCA1 tetramer transports PL from transport vesicle membrane to plasma membrane") "Reactome:R-HSA-216757") -AnnotationAssertion(Annotation(rdfs:label "ABCA7:Apo1A-mediated phospholipid efflux") "Reactome:R-HSA-382553") -AnnotationAssertion(Annotation(rdfs:label "ABCB4 transports PC from plasma membrane to extracellular region") "Reactome:R-HSA-5678706") -AnnotationAssertion(Annotation(rdfs:label "Defective ABCB4 does not transport PC from plasma membrane to extracellular region") "Reactome:R-HSA-5678749") -AnnotationAssertion(Annotation(rdfs:label "ESYT1:ESYT2:ESYT3 transport GPL from plasma membrane to ER membrane") "Reactome:R-HSA-8857662") -AnnotationAssertion(Annotation(rdfs:label "MFSD2A transports LPC from extracellular region to plasma membrane") "Reactome:R-HSA-8865637") -AnnotationAssertion(Annotation(rdfs:label "OSBPL5,8,10 exchange PS with PI4P from ER membrane to plasma membrane") "Reactome:R-HSA-8867876") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0005548") -AnnotationAssertion(rdfs:label "phospholipid transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "GO_REF:0000090") ObjectSomeValuesFrom( )) - # Class: (cellular_component) AnnotationAssertion(Annotation( "GOC:pdt") Annotation( "NIF_Subcellular:sao1337158144") "A location, relative to cellular compartments and structures, occupied by a macromolecular machine when it carries out a molecular function. There are two ways in which the gene ontology describes locations of gene products: (1) relative to cellular structures (e.g., cytoplasmic side of plasma membrane) or compartments (e.g., mitochondrion), and (2) the stable macromolecular complexes of which they are parts (e.g., the ribosome).") @@ -54094,11 +20783,9 @@ AnnotationAssertion(Annotation( "cellular_component") AnnotationAssertion( "GO:0005583") AnnotationAssertion(rdfs:label "fibrillar collagen trimer") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) -DisjointClasses( ) # Class: (collagen type I trimer) @@ -54215,81 +20902,7 @@ SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectAllValuesFrom( )) DisjointClasses( ) -DisjointClasses( ) DisjointClasses( ObjectSomeValuesFrom( )) -DisjointClasses( ObjectSomeValuesFrom( )) - -# Class: (nuclear envelope) - -AnnotationAssertion(Annotation( "ISBN:0198547684") "The double lipid bilayer enclosing the nucleus and separating its contents from the rest of the cytoplasm; includes the intermembrane space, a gap of width 20-40 nm (also called the perinuclear space).") -AnnotationAssertion( "GO:0005636") -AnnotationAssertion( "Wikipedia:Nuclear_envelope") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0005635") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "nuclear envelope") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (nuclear outer membrane) - -AnnotationAssertion(Annotation( "ISBN:0198547684") "The outer, i.e. cytoplasm-facing, lipid bilayer of the nuclear envelope; continuous with the endoplasmic reticulum of the cell and sometimes studded with ribosomes.") -AnnotationAssertion( "NIF_Subcellular:sao1617136075") -AnnotationAssertion( "nucleus outer envelope") -AnnotationAssertion( "perinuclear membrane") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0005640") -AnnotationAssertion(rdfs:label "nuclear outer membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (chromosome) - -AnnotationAssertion(Annotation( "ISBN:0198547684") "A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information.") -AnnotationAssertion( "Wikipedia:Chromosome") -AnnotationAssertion( "interphase chromosome") -AnnotationAssertion( "prophase chromosome") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "chromatid") -AnnotationAssertion( "GO:0005694") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "Chromosomes include parts that are not part of the chromatin. Examples include the kinetochore.") -AnnotationAssertion(rdfs:label "chromosome") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (nucleolus) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.") -AnnotationAssertion( "NIF_Subcellular:sao1820400233") -AnnotationAssertion( "Wikipedia:Nucleolus") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0005730") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "nucleolus") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) # Class: (cytoplasm) @@ -54309,47 +20922,6 @@ AnnotationAssertion(rdfs:label "cyto SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (lysosome) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "ISBN:0198506732") "A small lytic vacuole that has cell cycle-independent morphology found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions.") -AnnotationAssertion( ) -AnnotationAssertion( "NIF_Subcellular:sao585356902") -AnnotationAssertion( "Wikipedia:Lysosome") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0005764") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "lysosome") -SubClassOf( ) -SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) -DisjointClasses( ObjectSomeValuesFrom( )) - -# Class: (lysosomal membrane) - -AnnotationAssertion(Annotation( "GOC:ai") "The lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm.") -AnnotationAssertion( ) -AnnotationAssertion( "lysosome membrane") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0005765") -AnnotationAssertion(rdfs:label "lysosomal membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) -DisjointClasses( ObjectSomeValuesFrom( )) - -# Class: (primary lysosome) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0815316194") "A lysosome before it has fused with a vesicle or vacuole.") -AnnotationAssertion( "NIF_Subcellular:sao1140587416") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0005766") -AnnotationAssertion(rdfs:label "primary lysosome") -SubClassOf( ) - # Class: (vacuole) AnnotationAssertion(Annotation( "GOC:mtg_sensu") Annotation( "ISBN:0198506732") "A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol.") @@ -54371,109 +20943,6 @@ AnnotationAssertion(rdfs:label "vacu SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (vacuolar membrane) - -AnnotationAssertion(Annotation( "GOC:ai") "The lipid bilayer surrounding the vacuole and separating its contents from the cytoplasm of the cell.") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0005774") -AnnotationAssertion(rdfs:label "vacuolar membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (vacuolar lumen) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "The volume enclosed within the vacuolar membrane.") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0005775") -AnnotationAssertion(rdfs:label "vacuolar lumen") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (Golgi apparatus) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways.") -AnnotationAssertion( "Golgi") -AnnotationAssertion( "NIF_Subcellular:sao451912436") -AnnotationAssertion( "Wikipedia:Golgi_apparatus") -AnnotationAssertion( "Golgi complex") -AnnotationAssertion( "Golgi ribbon") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0005794") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "Note that the Golgi apparatus can be located in various places in the cytoplasm. In plants and lower animal cells, the Golgi apparatus exists as many copies of discrete stacks dispersed throughout the cytoplasm, while the Golgi apparatus of interphase mammalian cells is a juxtanuclear, often pericentriolar reticulum, where the discrete Golgi stacks are stitched together to form a compact and interconnected ribbon, sometimes called the Golgi ribbon.") -AnnotationAssertion(rdfs:label "Golgi apparatus") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - -# Class: (Golgi-associated vesicle) - -AnnotationAssertion(Annotation( "GOC:mah") "Any vesicle associated with the Golgi complex and involved in mediating transport within the Golgi or between the Golgi and other parts of the cell.") -AnnotationAssertion( "NIF_Subcellular:sao819927218") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "Golgi vesicle") -AnnotationAssertion(Annotation( "NIF_Subcellular:sao138219748") "vesicular component") -AnnotationAssertion( "GO:0005798") -AnnotationAssertion(rdfs:comment "Note that this definition includes vesicles that are transiently associated with the Golgi.") -AnnotationAssertion(rdfs:label "Golgi-associated vesicle") -SubClassOf( ) - -# Class: (cytosol) - -AnnotationAssertion(Annotation( "GOC:hjd") Annotation( "GOC:jl") "The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.") -AnnotationAssertion( "NIF_Subcellular:sao101633890") -AnnotationAssertion( "Wikipedia:Cytosol") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0005829") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "cytosol") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -DisjointClasses( ObjectSomeValuesFrom( )) -DisjointClasses( ObjectSomeValuesFrom( )) - -# Class: (ribosome) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "An intracellular organelle, about 200 A in diameter, consisting of RNA and protein. It is the site of protein biosynthesis resulting from translation of messenger RNA (mRNA). It consists of two subunits, one large and one small, each containing only protein and RNA. Both the ribosome and its subunits are characterized by their sedimentation coefficients, expressed in Svedberg units (symbol: S). Hence, the prokaryotic ribosome (70S) comprises a large (50S) subunit and a small (30S) subunit, while the eukaryotic ribosome (80S) comprises a large (60S) subunit and a small (40S) subunit. Two sites on the ribosomal large subunit are involved in translation, namely the aminoacyl site (A site) and peptidyl site (P site). Ribosomes from prokaryotes, eukaryotes, mitochondria, and chloroplasts have characteristically distinct ribosomal proteins.") -AnnotationAssertion( "GO:0033279") -AnnotationAssertion( "NIF_Subcellular:sao1429207766") -AnnotationAssertion( "Wikipedia:Ribosome") -AnnotationAssertion(Annotation( "NIF_Subcellular:sao1139385046") "free ribosome") -AnnotationAssertion(Annotation( "NIF_Subcellular:sao1291545653") "membrane bound ribosome") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "ribosomal RNA") -AnnotationAssertion( "GO:0005840") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "ribosome") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (cytoskeleton) AnnotationAssertion(Annotation( "GOC:mah") Annotation( "PMID:16959967") Annotation( "PMID:27419875") "A cellular structure that forms the internal framework of eukaryotic and prokaryotic cells. The cytoskeleton includes intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles.") @@ -54494,53 +20963,6 @@ AnnotationAssertion( "cytoskeleton") SubClassOf( ) -# Class: (microtubule) - -AnnotationAssertion(Annotation( "ISBN:0879693568") "Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle.") -AnnotationAssertion( "NIF_Subcellular:sao1846835077") -AnnotationAssertion( "Wikipedia:Microtubule") -AnnotationAssertion( "microtubuli") -AnnotationAssertion( "microtubulus") -AnnotationAssertion(Annotation( "NIF_Subcellular:sao248349196") "neurotubule") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0005874") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "microtubule") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (axonemal microtubule) - -AnnotationAssertion(Annotation( "GOC:cilia") Annotation( "ISBN:0815316194") "A microtubule in the axoneme of a eukaryotic cilium or flagellum; an axoneme contains nine modified doublet microtubules, which may or may not surround a pair of single microtubules.") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0005879") -AnnotationAssertion(rdfs:label "axonemal microtubule") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (nuclear microtubule) - -AnnotationAssertion(Annotation( "GOC:mah") "Any microtubule in the nucleus of a cell.") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0005880") -AnnotationAssertion(rdfs:label "nuclear microtubule") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cytoplasmic microtubule) - -AnnotationAssertion(Annotation( "GOC:mah") "Any microtubule in the cytoplasm of a cell.") -AnnotationAssertion( "non-spindle-associated astral microtubule") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0005881") -AnnotationAssertion(rdfs:label "cytoplasmic microtubule") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (intermediate filament) AnnotationAssertion(Annotation( "ISBN:0198506732") Annotation( "http://www.cytochemistry.net/Cell-biology/intermediate_filaments.htm") "A cytoskeletal structure that forms a distinct elongated structure, characteristically 10 nm in diameter, that occurs in the cytoplasm of eukaryotic cells. Intermediate filaments form a fibrous system, composed of chemically heterogeneous subunits and involved in mechanically integrating the various components of the cytoplasmic space. Intermediate filaments may be divided into five chemically distinct classes: Type I, acidic keratins; Type II, basic keratins; Type III, including desmin, vimentin and others; Type IV, neurofilaments and related filaments; and Type V, lamins.") @@ -54604,18 +21026,6 @@ AnnotationAssertion(rdfs:label "plas SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (insulin receptor complex) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "A disulfide-bonded, heterotetrameric receptor complex. The alpha chains are entirely extracellular, while each beta chain has one transmembrane domain. The ligand binds to the alpha subunit extracellular domain and the kinase is associated with the beta subunit intracellular domain.") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0005899") -AnnotationAssertion(rdfs:label "insulin receptor complex") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - # Class: (microvillus) AnnotationAssertion(Annotation( "ISBN:0815316194") "Thin cylindrical membrane-covered projections on the surface of an animal cell containing a core bundle of actin filaments. Present in especially large numbers on the absorptive surface of intestinal cells.") @@ -54709,40 +21119,6 @@ DisjointClasses( ObjectSomeValuesFrom DisjointClasses( ObjectSomeValuesFrom( )) DisjointClasses( ObjectSomeValuesFrom( )) -# Class: (axoneme) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:cilia") Annotation( "ISBN:0198547684") "The bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements.") -AnnotationAssertion( "GO:0035085") -AnnotationAssertion( "GO:0035086") -AnnotationAssertion( "Wikipedia:Axoneme") -AnnotationAssertion( "ciliary axoneme") -AnnotationAssertion( "cilium axoneme") -AnnotationAssertion( "flagellar axoneme") -AnnotationAssertion( "flagellum axoneme") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0005930") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "Note that cilia and eukaryotic flagella are deemed to be equivalent. In diplomonad species, such as Giardia, the axoneme may extend intracellularly up to 5um away from the plane of the plasma membrane.") -AnnotationAssertion(rdfs:label "axoneme") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cell cortex) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "ISBN:0815316194") "The region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins.") -AnnotationAssertion( "Wikipedia:Cell_cortex") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "cell periphery") -AnnotationAssertion( "peripheral cytoplasm") -AnnotationAssertion( "GO:0005938") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "cell cortex") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (carbohydrate metabolic process) AnnotationAssertion(Annotation( "GOC:mah") Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.") @@ -54767,23 +21143,8 @@ AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "carbohydrate metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (polysaccharide metabolic process) - -AnnotationAssertion(Annotation( "ISBN:0198547684") "The chemical reactions and pathways involving a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically.") -AnnotationAssertion( "GO:0044263") -AnnotationAssertion( "polysaccharide metabolism") -AnnotationAssertion( "glycan metabolic process") -AnnotationAssertion( "glycan metabolism") -AnnotationAssertion( "multicellular organismal polysaccharide metabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0005976") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "polysaccharide metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (glycogen metabolic process) AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues in alpha-(1->4) glycosidic linkage, joined together by alpha-(1->6) glycosidic linkages.") @@ -54791,7 +21152,6 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0005977") AnnotationAssertion(rdfs:label "glycogen metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ) @@ -54807,24 +21167,9 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0005978") AnnotationAssertion(rdfs:label "glycogen biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) -# Class: (regulation of glycogen biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen.") -AnnotationAssertion( "regulation of glycogen anabolism") -AnnotationAssertion( "regulation of glycogen biosynthesis") -AnnotationAssertion( "regulation of glycogen formation") -AnnotationAssertion( "regulation of glycogen synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0005979") -AnnotationAssertion(rdfs:label "regulation of glycogen biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - # Class: (glycogen catabolic process) AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues.") @@ -54836,83 +21181,6 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:0005980") AnnotationAssertion(rdfs:label "glycogen catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of glycogen catabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glycogen.") -AnnotationAssertion( "regulation of glycogen breakdown") -AnnotationAssertion( "regulation of glycogen catabolism") -AnnotationAssertion( "regulation of glycogen degradation") -AnnotationAssertion(Annotation( "GOC:sl") "regulation of glycogenolysis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0005981") -AnnotationAssertion(rdfs:label "regulation of glycogen catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (monosaccharide metabolic process) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving monosaccharides, the simplest carbohydrates. They are polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides.") -AnnotationAssertion( "monosaccharide metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0005996") -AnnotationAssertion(rdfs:label "monosaccharide metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (glucose metabolic process) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving glucose, the aldohexose gluco-hexose. D-glucose is dextrorotatory and is sometimes known as dextrose; it is an important source of energy for living organisms and is found free as well as combined in homo- and hetero-oligosaccharides and polysaccharides.") -AnnotationAssertion(Annotation( "GOC:vw") "cellular glucose metabolic process") -AnnotationAssertion( "glucose metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006006") -AnnotationAssertion(rdfs:label "glucose metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (glucose catabolic process) - -AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways resulting in the breakdown of glucose, the aldohexose gluco-hexose.") -AnnotationAssertion( "glucose breakdown") -AnnotationAssertion( "glucose catabolism") -AnnotationAssertion( "glucose degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006007") -AnnotationAssertion(rdfs:label "glucose catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (D-ribose metabolic process) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving D-ribose (ribo-pentose). As beta-D-ribofuranose, D-ribose forms the glycose group of all ribonucleosides, ribonucleotides and ribonucleic acids, and also of ribose phosphates, various glycosides, some coenzymes and some forms of vitamin B12.") -AnnotationAssertion( "D-ribose metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006014") -AnnotationAssertion(rdfs:label "D-ribose metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (aminoglycan metabolic process) - -AnnotationAssertion(Annotation( "GOC:ai") Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages.") -AnnotationAssertion( "aminoglycan metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006022") -AnnotationAssertion(rdfs:label "aminoglycan metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (aminoglycan biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:ai") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages.") -AnnotationAssertion( "aminoglycan anabolism") -AnnotationAssertion( "aminoglycan biosynthesis") -AnnotationAssertion( "aminoglycan formation") -AnnotationAssertion( "aminoglycan synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006023") -AnnotationAssertion(rdfs:label "aminoglycan biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (glycosaminoglycan biosynthetic process) @@ -54924,100 +21192,6 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0006024") AnnotationAssertion(rdfs:label "glycosaminoglycan biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (aminoglycan catabolic process) - -AnnotationAssertion(Annotation( "GOC:ai") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages.") -AnnotationAssertion( "aminoglycan breakdown") -AnnotationAssertion( "aminoglycan catabolism") -AnnotationAssertion( "aminoglycan degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006026") -AnnotationAssertion(rdfs:label "aminoglycan catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (glycosaminoglycan catabolic process) - -AnnotationAssertion(Annotation( "ISBN:0192800981") "The chemical reactions and pathways resulting in the breakdown of glycosaminoglycans, any one of a group of polysaccharides that contain amino sugars.") -AnnotationAssertion( "glycosaminoglycan breakdown") -AnnotationAssertion( "glycosaminoglycan catabolism") -AnnotationAssertion( "glycosaminoglycan degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006027") -AnnotationAssertion(rdfs:label "glycosaminoglycan catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (proteoglycan metabolic process) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans.") -AnnotationAssertion( "proteoglycan metabolism") -AnnotationAssertion( "proteoglycan sulfate transfer") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006029") -AnnotationAssertion(rdfs:label "proteoglycan metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (chitin metabolic process) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues.") -AnnotationAssertion( "beta-1,4-linked N-acetylglucosamine metabolic process") -AnnotationAssertion( "beta-1,4-linked N-acetylglucosamine metabolism") -AnnotationAssertion( "chitin metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006030") -AnnotationAssertion(rdfs:label "chitin metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (chitin biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues.") -AnnotationAssertion( "beta-1,4-linked N-acetylglucosamine biosynthesis") -AnnotationAssertion( "beta-1,4-linked N-acetylglucosamine biosynthetic process") -AnnotationAssertion( "chitin anabolism") -AnnotationAssertion( "chitin biosynthesis") -AnnotationAssertion( "chitin formation") -AnnotationAssertion( "chitin synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006031") -AnnotationAssertion(rdfs:label "chitin biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (chitin catabolic process) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues.") -AnnotationAssertion( "beta-1,4-linked N-acetylglucosamine catabolic process") -AnnotationAssertion( "beta-1,4-linked N-acetylglucosamine catabolism") -AnnotationAssertion( "chitin breakdown") -AnnotationAssertion( "chitin catabolism") -AnnotationAssertion( "chitin degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006032") -AnnotationAssertion(rdfs:label "chitin catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (amino sugar metabolic process) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0192801023") "The chemical reactions and pathways involving any amino sugar, sugars containing an amino group in place of a hydroxyl group.") -AnnotationAssertion( "amino sugar metabolism") -AnnotationAssertion( "aminosaccharide metabolic process") -AnnotationAssertion( "aminosaccharide metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006040") -AnnotationAssertion(rdfs:label "amino sugar metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (alcohol metabolic process) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom.") -AnnotationAssertion( "alcohol metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006066") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "alcohol metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) # Class: (cellular aldehyde metabolic process) @@ -55029,7 +21203,6 @@ AnnotationAssertion( "GO:0006081") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "cellular aldehyde metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ) @@ -55043,21 +21216,11 @@ AnnotationAssertion( "GO:0006082") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "organic acid metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) -# Class: (acetate metabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways involving acetate, the anion of acetic acid.") -AnnotationAssertion( "acetate metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006083") -AnnotationAssertion(rdfs:label "acetate metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (generation of precursor metabolites and energy) AnnotationAssertion(Annotation( "GOC:jl") "The chemical reactions and pathways resulting in the formation of precursor metabolites, substances from which energy is derived, and any process involved in the liberation of energy from these substances.") @@ -55079,42 +21242,6 @@ AnnotationAssertion( "generation of precursor metabolites and energy") SubClassOf( ) -# Class: (gluconeogenesis) - -AnnotationAssertion(Annotation( "MetaCyc:GLUCONEO-PWY") "The formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol.") -AnnotationAssertion( "MetaCyc:GLUCONEO-PWY") -AnnotationAssertion( "Wikipedia:Gluconeogenesis") -AnnotationAssertion( "glucose biosynthesis") -AnnotationAssertion( "glucose biosynthetic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006094") -AnnotationAssertion(rdfs:label "gluconeogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of carbohydrate metabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving carbohydrates.") -AnnotationAssertion( "regulation of carbohydrate metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006109") -AnnotationAssertion(rdfs:label "regulation of carbohydrate metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of gluconeogenesis) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of gluconeogenesis, the formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2013-01-18T12:47:43Z") -AnnotationAssertion( "GO:0090526") -AnnotationAssertion( "regulation of glucose biosynthesis") -AnnotationAssertion( "regulation of glucose biosynthetic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "regulation of gluconeogenesis involved in cellular glucose homeostasis") -AnnotationAssertion( "GO:0006111") -AnnotationAssertion(rdfs:label "regulation of gluconeogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (energy reserve metabolic process) AnnotationAssertion(Annotation( "GOC:mah") "The chemical reactions and pathways by which a cell derives energy from stored compounds such as fats or glycogen.") @@ -55125,300 +21252,6 @@ AnnotationAssertion( "energy reserve metabolic process") SubClassOf( ) -# Class: (fermentation) - -AnnotationAssertion(Annotation( "GOC:curators") Annotation( "ISBN:0201090910") Annotation( "MetaCyc:Fermentation") "The anaerobic enzymatic conversion of organic compounds, especially carbohydrates, coupling the oxidation and reduction of NAD/H and the generation of adenosine triphosphate (ATP).") -AnnotationAssertion( "MetaCyc:FERMENTATION-PWY") -AnnotationAssertion( "Wikipedia:Fermentation_(biochemistry)") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006113") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "fermentation") -SubClassOf( ) - -# Class: (nucleobase-containing compound metabolic process) - -AnnotationAssertion(Annotation( "GOC:ai") "Any cellular metabolic process involving nucleobases, nucleosides, nucleotides and nucleic acids.") -AnnotationAssertion( "GO:0055134") -AnnotationAssertion( "cellular nucleobase, nucleoside, nucleotide and nucleic acid metabolic process") -AnnotationAssertion( "cellular nucleobase, nucleoside, nucleotide and nucleic acid metabolism") -AnnotationAssertion( "nucleobase, nucleoside, nucleotide and nucleic acid metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "nucleobase, nucleoside and nucleotide metabolic process") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "nucleobase, nucleoside, nucleotide and nucleic acid metabolic process") -AnnotationAssertion( "GO:0006139") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "nucleobase-containing compound metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of nucleotide metabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleotides.") -AnnotationAssertion( "regulation of nucleotide metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006140") -AnnotationAssertion(rdfs:label "regulation of nucleotide metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of purine nucleobase metabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving purines.") -AnnotationAssertion(Annotation( "GOC:go_curators") "regulation of purine base metabolic process") -AnnotationAssertion( "regulation of purine base metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006141") -AnnotationAssertion(rdfs:label "regulation of purine nucleobase metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (purine nucleobase metabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways involving purine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, which include adenine and guanine.") -AnnotationAssertion(Annotation( "GOC:go_curators") "purine base metabolic process") -AnnotationAssertion( "purine base metabolism") -AnnotationAssertion( "purine metabolic process") -AnnotationAssertion( "purine metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006144") -AnnotationAssertion(rdfs:label "purine nucleobase metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (purine nucleobase catabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways resulting in the breakdown of purine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, which include adenine and guanine.") -AnnotationAssertion( "purine base breakdown") -AnnotationAssertion(Annotation( "GOC:go_curators") "purine base catabolic process") -AnnotationAssertion( "purine base catabolism") -AnnotationAssertion( "purine base degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006145") -AnnotationAssertion(rdfs:label "purine nucleobase catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (adenine catabolic process) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of adenine, 6-aminopurine, one of the 5 main bases found in nucleic acids and a component of numerous important derivatives of its corresponding ribonucleoside, adenosine.") -AnnotationAssertion( "adenine breakdown") -AnnotationAssertion( "adenine catabolism") -AnnotationAssertion( "adenine degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006146") -AnnotationAssertion(rdfs:label "adenine catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (purine nucleoside catabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways resulting in the breakdown of purine nucleoside, one of a family of organic molecules consisting of a purine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside).") -AnnotationAssertion( "purine nucleoside breakdown") -AnnotationAssertion( "purine nucleoside catabolism") -AnnotationAssertion( "purine nucleoside degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006152") -AnnotationAssertion(rdfs:label "purine nucleoside catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (adenosine catabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways resulting in the breakdown of adenosine, adenine riboside, a ribonucleoside found widely distributed in cells of every type as the free nucleoside and in combination in nucleic acids and various nucleoside coenzymes.") -AnnotationAssertion( "GO:0006156") -AnnotationAssertion( "adenosine breakdown") -AnnotationAssertion( "adenosine catabolism") -AnnotationAssertion( "adenosine degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "adenosine phosphorolysis") -AnnotationAssertion( "GO:0006154") -AnnotationAssertion(rdfs:label "adenosine catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (purine nucleotide metabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving a purine nucleotide, a compound consisting of nucleoside (a purine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.") -AnnotationAssertion( "purine nucleotide metabolism") -AnnotationAssertion( "purine metabolic process") -AnnotationAssertion( "purine metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006163") -AnnotationAssertion(rdfs:label "purine nucleotide metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (purine nucleotide biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of a purine nucleotide, a compound consisting of nucleoside (a purine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.") -AnnotationAssertion( "MetaCyc:DENOVOPURINE2-PWY") -AnnotationAssertion( "purine nucleotide anabolism") -AnnotationAssertion( "purine nucleotide biosynthesis") -AnnotationAssertion( "purine nucleotide formation") -AnnotationAssertion( "purine nucleotide synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006164") -AnnotationAssertion(rdfs:label "purine nucleotide biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (ADP biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways resulting in the formation of ADP, adenosine 5'-diphosphate.") -AnnotationAssertion( "ADP anabolism") -AnnotationAssertion( "ADP biosynthesis") -AnnotationAssertion( "ADP formation") -AnnotationAssertion( "ADP synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006172") -AnnotationAssertion(rdfs:label "ADP biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (purine nucleotide catabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of a purine nucleotide, a compound consisting of nucleoside (a purine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.") -AnnotationAssertion( "purine nucleotide breakdown") -AnnotationAssertion( "purine nucleotide catabolism") -AnnotationAssertion( "purine nucleotide degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006195") -AnnotationAssertion(rdfs:label "purine nucleotide catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (DNA metabolic process) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "Any cellular metabolic process involving deoxyribonucleic acid. This is one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides.") -AnnotationAssertion( "GO:0055132") -AnnotationAssertion( "DNA metabolism") -AnnotationAssertion( "cellular DNA metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006259") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "DNA metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (DNA catabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198506732") "The cellular DNA metabolic process resulting in the breakdown of DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long unbranched macromolecule formed from one or two strands of linked deoxyribonucleotides, the 3'-phosphate group of each constituent deoxyribonucleotide being joined in 3',5'-phosphodiester linkage to the 5'-hydroxyl group of the deoxyribose moiety of the next one.") -AnnotationAssertion( "DNA breakdown") -AnnotationAssertion( "DNA catabolism") -AnnotationAssertion( "DNA degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006308") -AnnotationAssertion(rdfs:label "DNA catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (apoptotic DNA fragmentation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mah") Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:tb") Annotation( "ISBN:0721639976") Annotation( "PMID:15723341") Annotation( "PMID:23379520") "The cleavage of DNA during apoptosis, which usually occurs in two stages: cleavage into fragments of about 50 kbp followed by cleavage between nucleosomes to yield 200 bp fragments.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/24396"^^xsd:anyURI) -AnnotationAssertion( "GO:0008178") -AnnotationAssertion( "DNA fragmentation") -AnnotationAssertion(Annotation( "GOC:mtg_apoptosis") "chromatinolysis") -AnnotationAssertion( "DNA catabolic process during apoptosis") -AnnotationAssertion( "DNA catabolism during apoptosis") -AnnotationAssertion(Annotation( "GOC:cjm") Annotation( "GOC:dph") Annotation( "GOC:tb") "DNA fragmentation involved in apoptotic nuclear change") -AnnotationAssertion( "endonucleolytic DNA catabolic process involved in apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006309") -AnnotationAssertion(rdfs:comment "DNA fragmentation in response to apoptotic signals is achieved through the activity of apoptotic nucleases. In human, these include DNA fragmentation factor (DFF) or caspase-activated DNase (CAD) and endonuclease G (Endo G) (reviewed in PMID:15723341). Caution is needed when apoptotic DNA laddering assays show presence of fragmented DNA. A positive assay may simply reflect the end point of a whole apoptotic process. Unless clear experimental evidence is available to show that a gene product is directly involved in fragmenting DNA, please do not annotate to GO:0006309 'apoptotic DNA fragmentation' and consider annotating instead to a more upstream process such as, e.g., GO:0042981 'regulation of apoptotic process', GO:0006915 'apoptotic process', GO:0097190 'apoptotic signaling pathway'. Also, note that gene products involved in compartmentalization of apoptotic nucleases and in activation or repression of their enzymatic activity should be annotated to the regulation term GO:1902510 'regulation of apoptotic DNA fragmentation' or to one of its children (see PMID:15723341).") -AnnotationAssertion(rdfs:label "apoptotic DNA fragmentation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (DNA recombination) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "Any process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Interchromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006310") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "DNA recombination") -SubClassOf( ) - -# Class: (chromatin organization) - -AnnotationAssertion(Annotation( "PMID:20404130") "The assembly or remodeling of chromatin composed of DNA complexed with histones, other associated proteins, and sometimes RNA.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/22130"^^xsd:anyURI) -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/23549"^^xsd:anyURI) -AnnotationAssertion( "GO:0006333") -AnnotationAssertion( "GO:0006336") -AnnotationAssertion( "GO:0016568") -AnnotationAssertion( "GO:0031497") -AnnotationAssertion( "GO:0034724") -AnnotationAssertion( "chromatin maintenance") -AnnotationAssertion(Annotation( "GOC:mah") "chromatin organisation") -AnnotationAssertion(Annotation( "GOC:mah") "establishment of chromatin architecture") -AnnotationAssertion(Annotation( "GOC:mah") "establishment or maintenance of chromatin architecture") -AnnotationAssertion( "DNA replication-independent chromatin assembly") -AnnotationAssertion( "DNA replication-independent chromatin organization") -AnnotationAssertion( "DNA replication-independent nucleosome organisation") -AnnotationAssertion( "DNA replication-independent nuclesome assembly") -AnnotationAssertion( "chromatin assembly") -AnnotationAssertion( "transcription-coupled nucleosome assembly") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "chromatin assembly or disassembly") -AnnotationAssertion( "chromatin assembly/disassembly") -AnnotationAssertion( "chromatin modification") -AnnotationAssertion( "GO:0006325") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "chromatin organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (RNA catabolic process) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage.") -AnnotationAssertion( "RNA breakdown") -AnnotationAssertion( "RNA catabolism") -AnnotationAssertion( "RNA degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006401") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "RNA catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (RNA localization) - -AnnotationAssertion(Annotation( "GOC:ai") "A process in which RNA is transported to, or maintained in, a specific location.") -AnnotationAssertion(Annotation( "GOC:mah") "RNA localisation") -AnnotationAssertion( "establishment and maintenance of RNA localization") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006403") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "RNA localization") -SubClassOf( ) - -# Class: (RNA import into nucleus) - -AnnotationAssertion(Annotation( "GOC:ma") "The import of RNA from the cytoplasm to the nucleus.") -AnnotationAssertion( "RNA import into cell nucleus") -AnnotationAssertion( "RNA transport from cytoplasm to nucleus") -AnnotationAssertion( "RNA-nucleus import") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006404") -AnnotationAssertion(rdfs:label "RNA import into nucleus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (RNA export from nucleus) - -AnnotationAssertion(Annotation( "GOC:ma") "The directed movement of RNA from the nucleus to the cytoplasm.") -AnnotationAssertion( "RNA export from cell nucleus") -AnnotationAssertion( "RNA export out of nucleus") -AnnotationAssertion( "RNA transport from nucleus to cytoplasm") -AnnotationAssertion( "RNA-nucleus export") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006405") -AnnotationAssertion(rdfs:label "RNA export from nucleus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - # Class: (translation) AnnotationAssertion(Annotation( "GOC:go_curators") "The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome.") @@ -55442,7 +21275,6 @@ AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "translation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) @@ -55495,74 +21327,6 @@ AnnotationAssertion(rdfs:label "tran SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (regulation of translation) - -AnnotationAssertion(Annotation( "GOC:isa_complete") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA.") -AnnotationAssertion( "GO:0006445") -AnnotationAssertion( "regulation of protein anabolism") -AnnotationAssertion( "regulation of protein biosynthesis") -AnnotationAssertion( "regulation of protein formation") -AnnotationAssertion( "regulation of protein synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006417") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "regulation of translation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of translational initiation) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of translational initiation.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006446") -AnnotationAssertion(rdfs:label "regulation of translational initiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (regulation of translational elongation) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate, extent or accuracy of translational elongation.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006448") -AnnotationAssertion(rdfs:label "regulation of translational elongation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (regulation of translational termination) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of translational termination.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006449") -AnnotationAssertion(rdfs:label "regulation of translational termination") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (protein phosphorylation) - -AnnotationAssertion(Annotation( "GOC:hb") "The process of introducing a phosphate group on to a protein.") -AnnotationAssertion(Annotation( "GOC:bf") "protein amino acid phosphorylation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006468") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "protein phosphorylation") -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of protein kinase activity) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of protein kinase activity.") -AnnotationAssertion( "down regulation of protein kinase activity") -AnnotationAssertion( "down-regulation of protein kinase activity") -AnnotationAssertion( "downregulation of protein kinase activity") -AnnotationAssertion( "inhibition of protein kinase activity") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006469") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "negative regulation of protein kinase activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - # Class: (proteolysis) AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:mah") "The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.") @@ -55578,28 +21342,6 @@ AnnotationAssertion(rdfs:comment "Th AnnotationAssertion(rdfs:label "proteolysis") SubClassOf( ) -# Class: (glycoprotein catabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide.") -AnnotationAssertion( "glycoprotein breakdown") -AnnotationAssertion( "glycoprotein catabolism") -AnnotationAssertion( "glycoprotein degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006516") -AnnotationAssertion(rdfs:label "glycoprotein catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (peptide metabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways involving peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another.") -AnnotationAssertion( "peptide metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006518") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "peptide metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (amino acid metabolic process) AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving amino acids, carboxylic acids containing one or more amino groups.") @@ -55619,23 +21361,10 @@ AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "amino acid metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ) -# Class: (regulation of cellular amino acid metabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amino acids.") -AnnotationAssertion( "regulation of amino acid metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006521") -AnnotationAssertion(rdfs:label "regulation of cellular amino acid metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - # Class: (glutamate metabolic process) AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways involving glutamate, the anion of 2-aminopentanedioic acid.") @@ -55646,45 +21375,9 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0006536") AnnotationAssertion(rdfs:label "glutamate metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) -# Class: (glutamate biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways resulting in the formation of glutamate, the anion of 2-aminopentanedioic acid.") -AnnotationAssertion( "glutamate anabolism") -AnnotationAssertion( "glutamate biosynthesis") -AnnotationAssertion( "glutamate formation") -AnnotationAssertion( "glutamate synthesis") -AnnotationAssertion( "glutamic acid biosynthesis") -AnnotationAssertion( "glutamic acid biosynthetic process") -AnnotationAssertion( "glutamate biosynthesis, using glutamate dehydrogenase (NAD(P)+)") -AnnotationAssertion( "glutamate biosynthesis, using glutamate synthase (NADPH)") -AnnotationAssertion( "glutamate biosynthetic process, using glutamate dehydrogenase (NAD(P)+)") -AnnotationAssertion( "glutamate biosynthetic process, using glutamate synthase (NADPH)") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006537") -AnnotationAssertion(rdfs:label "glutamate biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (glutamate catabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways resulting in the breakdown of glutamate, the anion of 2-aminopentanedioic acid.") -AnnotationAssertion( "GO:0019459") -AnnotationAssertion( "glutamate breakdown") -AnnotationAssertion( "glutamate catabolism") -AnnotationAssertion( "glutamate degradation") -AnnotationAssertion( "glutamic acid catabolic process") -AnnotationAssertion( "glutamic acid catabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "glutamate deamidation") -AnnotationAssertion( "GO:0006538") -AnnotationAssertion(rdfs:label "glutamate catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - # Class: (cellular modified amino acid metabolic process) AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways involving compounds derived from amino acids, organic acids containing one or more amino substituents.") @@ -55700,7 +21393,6 @@ AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "cellular modified amino acid metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) @@ -55714,18 +21406,6 @@ AnnotationAssertion( "biogenic amine metabolic process") SubClassOf( ) -# Class: (acetylcholine catabolic process) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0192800752") "The chemical reactions and pathways resulting in the breakdown of acetylcholine, the acetic acid ester of the organic base choline.") -AnnotationAssertion( "acetylcholine breakdown") -AnnotationAssertion( "acetylcholine catabolism") -AnnotationAssertion( "acetylcholine degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006581") -AnnotationAssertion(rdfs:label "acetylcholine catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - # Class: (catecholamine metabolic process) AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine.") @@ -55733,22 +21413,9 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0006584") AnnotationAssertion(rdfs:label "catecholamine metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) -# Class: (indolalkylamine metabolic process) - -AnnotationAssertion(Annotation( "GOC:curators") "The chemical reactions and pathways involving indolalkylamines, indole or indole derivatives containing a primary, secondary, or tertiary amine group.") -AnnotationAssertion( "indolamine metabolic process") -AnnotationAssertion( "indolamine metabolism") -AnnotationAssertion( "indolalkylamine metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006586") -AnnotationAssertion(rdfs:label "indolalkylamine metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - # Class: (thyroid hormone generation) AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0716720094") "The formation of either of the compounds secreted by the thyroid gland, mainly thyroxine and triiodothyronine. This is achieved by the iodination and joining of tyrosine molecules to form the precursor thyroglobin, proteolysis of this precursor gives rise to the thyroid hormones.") @@ -55758,43 +21425,6 @@ AnnotationAssertion(rdfs:comment "No AnnotationAssertion(rdfs:label "thyroid hormone generation") SubClassOf( ) -# Class: (protein import into nucleus) - -AnnotationAssertion(Annotation( "GOC:jl") "The directed movement of a protein from the cytoplasm to the nucleus.") -AnnotationAssertion(Annotation( "GOC:mah") "establishment of protein localization to nucleus") -AnnotationAssertion( "protein import into cell nucleus") -AnnotationAssertion( "protein nucleus import") -AnnotationAssertion( "protein transport from cytoplasm to nucleus") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006606") -AnnotationAssertion(rdfs:label "protein import into nucleus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (protein export from nucleus) - -AnnotationAssertion(Annotation( "GOC:jl") "The directed movement of a protein from the nucleus into the cytoplasm.") -AnnotationAssertion( "GO:0097349") -AnnotationAssertion( "protein export from cell nucleus") -AnnotationAssertion( "protein export out of nucleus") -AnnotationAssertion( "protein transport from nucleus to cytoplasm") -AnnotationAssertion( "protein-nucleus export") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:al") "copper-induced protein export from nucleus") -AnnotationAssertion( "GO:0006611") -AnnotationAssertion(rdfs:label "protein export from nucleus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (vacuolar protein processing) - -AnnotationAssertion(Annotation( "GOC:mah") "Protein processing that takes place in the vacuole. Most protein processing in the vacuole represents proteolytic cleavage of precursors to form active enzymes.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "vacuolar protein maturation") -AnnotationAssertion( "vacuolar proteolysis") -AnnotationAssertion( "GO:0006624") -AnnotationAssertion(rdfs:label "vacuolar protein processing") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - # Class: (lipid metabolic process) AnnotationAssertion(Annotation( "GOC:ma") "The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids.") @@ -55815,149 +21445,10 @@ AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "lipid metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ) -# Class: (fatty acid metabolic process) - -AnnotationAssertion(Annotation( "ISBN:0198547684") "The chemical reactions and pathways involving fatty acids, aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis.") -AnnotationAssertion( "Wikipedia:Fatty_acid_metabolism") -AnnotationAssertion( "fatty acid metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006631") -AnnotationAssertion(rdfs:label "fatty acid metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (fatty acid biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes.") -AnnotationAssertion( "GO:0000037") -AnnotationAssertion( "MetaCyc:FASYN-INITIAL-PWY") -AnnotationAssertion( "MetaCyc:PWY-4381") -AnnotationAssertion( "MetaCyc:PWY-5156") -AnnotationAssertion( "Wikipedia:Fatty_acid_synthesis") -AnnotationAssertion( "fatty acid anabolism") -AnnotationAssertion( "fatty acid biosynthesis") -AnnotationAssertion( "fatty acid formation") -AnnotationAssertion( "fatty acid synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006633") -AnnotationAssertion(rdfs:label "fatty acid biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (membrane lipid metabolic process) - -AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways involving membrane lipids, any lipid found in or associated with a biological membrane.") -AnnotationAssertion( "membrane lipid metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006643") -AnnotationAssertion(rdfs:label "membrane lipid metabolic process") -SubClassOf( ) - -# Class: (phospholipid metabolic process) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving phospholipids, any lipid containing phosphoric acid as a mono- or diester.") -AnnotationAssertion( "phospholipid metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006644") -AnnotationAssertion(rdfs:label "phospholipid metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (glycolipid metabolic process) - -AnnotationAssertion(Annotation( "ISBN:0198547684") "The chemical reactions and pathways involving glycolipids, a class of 1,2-di-O-acylglycerols joined at oxygen 3 by a glycosidic linkage to a carbohydrate part (usually a mono-, di- or tri-saccharide). Some substances classified as bacterial glycolipids have the sugar group acylated by one or more fatty acids and the glycerol group may be absent.") -AnnotationAssertion( "glycolipid metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006664") -AnnotationAssertion(rdfs:label "glycolipid metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (sphingolipid metabolic process) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).") -AnnotationAssertion( "sphingolipid metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006665") -AnnotationAssertion(rdfs:label "sphingolipid metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (ceramide metabolic process) - -AnnotationAssertion(Annotation( "ISBN:0198547684") "The chemical reactions and pathways involving ceramides, any N-acylated sphingoid.") -AnnotationAssertion( "ceramide metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006672") -AnnotationAssertion(rdfs:label "ceramide metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (glycosylceramide metabolic process) - -AnnotationAssertion(Annotation( "GOC:ai") Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving glycosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of a monosaccharide (or derivative) by a ceramide group.") -AnnotationAssertion( "glycosylceramide metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006677") -AnnotationAssertion(rdfs:label "glycosylceramide metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (galactosylceramide metabolic process) - -AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways involving galactosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of galactose by a ceramide group.") -AnnotationAssertion( "galactosylceramide metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006681") -AnnotationAssertion(rdfs:label "galactosylceramide metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (galactosylceramide biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways resulting in the formation of galactosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of galactose by a ceramide group.") -AnnotationAssertion( "galactosylceramide anabolism") -AnnotationAssertion( "galactosylceramide biosynthesis") -AnnotationAssertion( "galactosylceramide formation") -AnnotationAssertion( "galactosylceramide synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006682") -AnnotationAssertion(rdfs:label "galactosylceramide biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (galactosylceramide catabolic process) - -AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways resulting in the breakdown of galactosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of galactose by a ceramide group.") -AnnotationAssertion( "galactosylceramide breakdown") -AnnotationAssertion( "galactosylceramide catabolism") -AnnotationAssertion( "galactosylceramide degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006683") -AnnotationAssertion(rdfs:label "galactosylceramide catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (glycosphingolipid metabolic process) - -AnnotationAssertion(Annotation( "ISBN:0198547684") "The chemical reactions and pathways involving glycosphingolipids, any compound with residues of sphingoid and at least one monosaccharide.") -AnnotationAssertion( "glycosphingolipid metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006687") -AnnotationAssertion(rdfs:label "glycosphingolipid metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (glycosphingolipid biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways resulting in the formation of glycosphingolipid, a compound with residues of sphingoid and at least one monosaccharide.") -AnnotationAssertion( "glycosphingolipid anabolism") -AnnotationAssertion( "glycosphingolipid biosynthesis") -AnnotationAssertion( "glycosphingolipid formation") -AnnotationAssertion( "glycosphingolipid synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006688") -AnnotationAssertion(rdfs:label "glycosphingolipid biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (steroid biosynthetic process) AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus; includes de novo formation and steroid interconversion by modification.") @@ -55970,7 +21461,6 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0006694") AnnotationAssertion(rdfs:label "steroid biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ) @@ -55985,7 +21475,6 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0006699") AnnotationAssertion(rdfs:label "bile acid biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ) @@ -56001,24 +21490,11 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0006700") AnnotationAssertion(rdfs:label "C21-steroid hormone biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) -# Class: (progesterone biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "http://www.cogsci.princeton.edu/") "The chemical reactions and pathways resulting in the formation of progesterone, a steroid hormone produced in the ovary which prepares and maintains the uterus for pregnancy. Also found in plants.") -AnnotationAssertion( "progesterone anabolism") -AnnotationAssertion( "progesterone biosynthesis") -AnnotationAssertion( "progesterone formation") -AnnotationAssertion( "progesterone synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006701") -AnnotationAssertion(rdfs:label "progesterone biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (glucocorticoid biosynthetic process) AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of glucocorticoids, hormonal C21 corticosteroids synthesized from cholesterol.") @@ -56029,7 +21505,6 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0006704") AnnotationAssertion(rdfs:label "glucocorticoid biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (mineralocorticoid biosynthetic process) @@ -56041,134 +21516,8 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0006705") AnnotationAssertion(rdfs:label "mineralocorticoid biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (steroid catabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways resulting in the breakdown of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.") -AnnotationAssertion( "steroid breakdown") -AnnotationAssertion( "steroid catabolism") -AnnotationAssertion( "steroid degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006706") -AnnotationAssertion(rdfs:label "steroid catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (progesterone catabolic process) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "http://www.cogsci.princeton.edu/") "The chemical reactions and pathways resulting in the breakdown of progesterone, a steroid hormone produced in the ovary which prepares and maintains the uterus for pregnancy. Also found in plants.") -AnnotationAssertion( "progesterone breakdown") -AnnotationAssertion( "progesterone catabolism") -AnnotationAssertion( "progesterone degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006709") -AnnotationAssertion(rdfs:label "progesterone catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (mineralocorticoid catabolic process) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of mineralocorticoids, hormonal C21 corticosteroids synthesized from cholesterol.") -AnnotationAssertion( "mineralocorticoid breakdown") -AnnotationAssertion( "mineralocorticoid catabolism") -AnnotationAssertion( "mineralocorticoid degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006712") -AnnotationAssertion(rdfs:label "mineralocorticoid catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (glucocorticoid catabolic process) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of glucocorticoids, hormonal C21 corticosteroids synthesized from cholesterol.") -AnnotationAssertion( "glucocorticoid breakdown") -AnnotationAssertion( "glucocorticoid catabolism") -AnnotationAssertion( "glucocorticoid degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006713") -AnnotationAssertion(rdfs:label "glucocorticoid catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (sesquiterpenoid metabolic process) - -AnnotationAssertion(Annotation( "ISBN:0198547684") "The chemical reactions and pathways involving sesquiterpenoid compounds, terpenoids with three isoprene units.") -AnnotationAssertion( "sesquiterpenoid metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006714") -AnnotationAssertion(rdfs:label "sesquiterpenoid metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (juvenile hormone metabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198547684") "The chemical reactions and pathways involving juvenile hormones, the three sesquiterpenoid derivatives that function to maintain the larval state of insects at molting and that may be required for other processes, e.g. oogenesis.") -AnnotationAssertion( "juvenile hormone metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006716") -AnnotationAssertion(rdfs:label "juvenile hormone metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (juvenile hormone biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198547684") "The chemical reactions and pathways resulting in the formation of juvenile hormones, the three sesquiterpenoid derivatives that function to maintain the larval state of insects at molting and that may be required for other processes, e.g. oogenesis.") -AnnotationAssertion( "juvenile hormone anabolism") -AnnotationAssertion( "juvenile hormone biosynthesis") -AnnotationAssertion( "juvenile hormone formation") -AnnotationAssertion( "juvenile hormone synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006718") -AnnotationAssertion(rdfs:label "juvenile hormone biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (juvenile hormone catabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198547684") "The chemical reactions and pathways resulting in the breakdown of juvenile hormones, the three sesquiterpenoid derivatives that function to maintain the larval state of insects at molting and that may be required for other processes, e.g. oogenesis.") -AnnotationAssertion( "juvenile hormone breakdown") -AnnotationAssertion( "juvenile hormone catabolism") -AnnotationAssertion( "juvenile hormone degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006719") -AnnotationAssertion(rdfs:label "juvenile hormone catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (isoprenoid metabolic process) - -AnnotationAssertion(Annotation( "ISBN:0198547684") "The chemical reactions and pathways involving isoprenoid compounds, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues.") -AnnotationAssertion( "GO:0016096") -AnnotationAssertion( "isoprenoid metabolism") -AnnotationAssertion( "polyisoprenoid metabolic process") -AnnotationAssertion( "polyisoprenoid metabolism") -AnnotationAssertion( "polyterpene metabolic process") -AnnotationAssertion( "polyterpene metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006720") -AnnotationAssertion(rdfs:label "isoprenoid metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (terpenoid metabolic process) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving terpenoids, any member of a class of compounds characterized by an isoprenoid chemical structure and including derivatives with various functional groups.") -AnnotationAssertion( "terpenoid metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006721") -AnnotationAssertion(rdfs:label "terpenoid metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cuticle hydrocarbon biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways resulting in the formation of hydrocarbons that make up the cuticle, the outer layer of some animals and plants, which acts to prevent water loss.") -AnnotationAssertion( "cuticle hydrocarbon anabolism") -AnnotationAssertion( "cuticle hydrocarbon biosynthesis") -AnnotationAssertion( "cuticle hydrocarbon formation") -AnnotationAssertion( "cuticle hydrocarbon synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006723") -AnnotationAssertion(rdfs:label "cuticle hydrocarbon biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - # Class: (cellular aromatic compound metabolic process) AnnotationAssertion(Annotation( "GOC:ai") Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving aromatic compounds, any organic compound characterized by one or more planar rings, each of which contains conjugated double bonds and delocalized pi electrons, as carried out by individual cells.") @@ -56179,109 +21528,8 @@ AnnotationAssertion( "GO:0006725") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "cellular aromatic compound metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (nucleoside phosphate metabolic process) - -AnnotationAssertion(Annotation( "GOC:mah") "The chemical reactions and pathways involving any phosphorylated nucleoside.") -AnnotationAssertion( "nucleoside phosphate metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006753") -AnnotationAssertion(rdfs:label "nucleoside phosphate metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (ATP biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.") -AnnotationAssertion( "GO:0006758") -AnnotationAssertion( "GO:0006759") -AnnotationAssertion( "ATP anabolism") -AnnotationAssertion( "ATP biosynthesis") -AnnotationAssertion( "ATP formation") -AnnotationAssertion( "ATP synthesis") -AnnotationAssertion( "ATP regeneration") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006754") -AnnotationAssertion(rdfs:label "ATP biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (porphyrin-containing compound metabolic process) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0198506732") Annotation( "Wikipedia:Porphyrin#Natural_formation") "The chemical reactions and pathways involving any member of a large group of derivatives or analogs of porphyrin. Porphyrins consists of a ring of four pyrrole nuclei linked each to the next at their alpha positions through a methine group.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "porphyrin metabolic process") -AnnotationAssertion( "porphyrin metabolism") -AnnotationAssertion( "GO:0006778") -AnnotationAssertion(rdfs:label "porphyrin-containing compound metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (porphyrin-containing compound biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0198506732") Annotation( "Wikipedia:Porphyrin#Natural_formation") "The chemical reactions and pathways resulting in the formation of any member of a large group of derivatives or analogs of porphyrin. Porphyrin consists of a ring of four pyrrole nuclei linked each to the next at their alpha positions through a methine group.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "porphyrin anabolism") -AnnotationAssertion( "porphyrin biosynthesis") -AnnotationAssertion( "porphyrin biosynthetic process") -AnnotationAssertion( "porphyrin formation") -AnnotationAssertion( "porphyrin synthesis") -AnnotationAssertion( "GO:0006779") -AnnotationAssertion(rdfs:label "porphyrin-containing compound biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (porphyrin-containing compound catabolic process) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of any member of a large group of derivatives or analogs of porphyrin. Porphyrin consists of a ring of four pyrrole nuclei linked each to the next at their alpha positions through a methine group.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "porphyrin breakdown") -AnnotationAssertion( "porphyrin catabolic process") -AnnotationAssertion( "porphyrin catabolism") -AnnotationAssertion( "porphyrin degradation") -AnnotationAssertion( "GO:0006787") -AnnotationAssertion(rdfs:label "porphyrin-containing compound catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (sulfur compound metabolic process) - -AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways involving the nonmetallic element sulfur or compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione.") -AnnotationAssertion( "Wikipedia:Sulfur_metabolism") -AnnotationAssertion( "sulfur metabolism") -AnnotationAssertion( "sulphur metabolic process") -AnnotationAssertion( "sulphur metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006790") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "sulfur compound metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (phosphorus metabolic process) - -AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways involving the nonmetallic element phosphorus or compounds that contain phosphorus, usually in the form of a phosphate group (PO4).") -AnnotationAssertion( "phosphorus metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006793") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "phosphorus metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (phosphate-containing compound metabolic process) - -AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways involving the phosphate group, the anion or salt of any phosphoric acid.") -AnnotationAssertion( "phosphate metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "phosphate metabolic process") -AnnotationAssertion( "GO:0006796") -AnnotationAssertion(rdfs:label "phosphate-containing compound metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (nitrogen compound metabolic process) AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving organic or inorganic compounds that contain nitrogen.") @@ -56291,7 +21539,6 @@ AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "nitrogen compound metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (transport) @@ -56316,111 +21563,14 @@ AnnotationAssertion(rdfs:comment "No AnnotationAssertion(rdfs:label "transport") SubClassOf( ) -# Class: (monoatomic ion transport) - -AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of a monoatomic ion into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Monatomic ions (also called simple ions) are ions consisting of exactly one atom.") -AnnotationAssertion( "ion transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006811") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "monoatomic ion transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (monoatomic cation transport) - -AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of a monoatomic cation, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Monatomic cations (also called simple cations) are positively charged ions consisting of exactly one atom.") -AnnotationAssertion( "GO:0006819") -AnnotationAssertion( "GO:0015674") -AnnotationAssertion( "GO:0072512") -AnnotationAssertion( "cation transport") -AnnotationAssertion(Annotation( "GOC:mah") "di-, tri-valent inorganic cation transport") -AnnotationAssertion( "trivalent inorganic cation transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006812") -AnnotationAssertion(rdfs:label "monoatomic cation transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (sodium ion transport) - -AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion( "GO:0006834") -AnnotationAssertion( "GO:0016974") -AnnotationAssertion( "sodium/potassium transport") -AnnotationAssertion( "sodium transport") -AnnotationAssertion( "mitochondrial sodium/calcium ion exchange") -AnnotationAssertion( "sodium:calcium exchange") -AnnotationAssertion( "sodium:solute transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:mah") "sodium channel auxiliary protein activity") -AnnotationAssertion( "GO:0006814") -AnnotationAssertion(rdfs:label "sodium ion transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (calcium ion transport) - -AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of calcium (Ca) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion( "calcium transport") -AnnotationAssertion( "mitochondrial sodium/calcium ion exchange") -AnnotationAssertion( "sodium:calcium exchange") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006816") -AnnotationAssertion(rdfs:label "calcium ion transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (phosphate ion transport) - -AnnotationAssertion(Annotation( "GOC:krc") "The directed movement of phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "phosphate transport") -AnnotationAssertion( "GO:0006817") -AnnotationAssertion(rdfs:label "phosphate ion transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (iron ion transport) - -AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of iron (Fe) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2012-04-18T03:33:45Z") -AnnotationAssertion( "GO:0015681") -AnnotationAssertion( "GO:0015682") -AnnotationAssertion( "GO:0015684") -AnnotationAssertion( "GO:0033216") -AnnotationAssertion( "GO:0097286") -AnnotationAssertion( "iron transport") -AnnotationAssertion( "ferric ion import") -AnnotationAssertion( "ferric ion transport") -AnnotationAssertion( "ferric iron import") -AnnotationAssertion( "ferric iron transport") -AnnotationAssertion( "ferric iron uptake") -AnnotationAssertion( "ferrous ion transport") -AnnotationAssertion( "ferrous iron transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "iron ion import") -AnnotationAssertion( "GO:0006826") -AnnotationAssertion(rdfs:label "iron ion transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (water transport) AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of water (H2O) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0006833") AnnotationAssertion(rdfs:label "water transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (dicarboxylic acid transport) - -AnnotationAssertion(Annotation( "GOC:krc") "The directed movement of dicarboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion( "GO:0006841") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "sodium:dicarboxylate transport") -AnnotationAssertion( "GO:0006835") -AnnotationAssertion(rdfs:label "dicarboxylic acid transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (neurotransmitter transport) AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Neurotransmitters are any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell.") @@ -56439,61 +21589,6 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:0006837") AnnotationAssertion(rdfs:label "serotonin transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (acetate transport) - -AnnotationAssertion(Annotation( "GOC:krc") "The directed movement of acetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006846") -AnnotationAssertion(rdfs:label "acetate transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (plasma membrane acetate transport) - -AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of acetate across a plasma membrane.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006847") -AnnotationAssertion(rdfs:label "plasma membrane acetate transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (extracellular transport) - -AnnotationAssertion(Annotation( "GOC:go_curators") "The transport of substances that occurs outside cells.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006858") -AnnotationAssertion(rdfs:label "extracellular transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (extracellular amino acid transport) - -AnnotationAssertion(Annotation( "GOC:ai") "The directed extracellular movement of amino acids.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006860") -AnnotationAssertion(rdfs:label "extracellular amino acid transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (nucleotide transport) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "The directed movement of a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate, into, out of or within a cell.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006862") -AnnotationAssertion(rdfs:label "nucleotide transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (purine nucleobase transport) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "The directed movement of purine bases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion( "GO:0015852") -AnnotationAssertion(Annotation( "GOC:mah") "purine base transmembrane transport") -AnnotationAssertion(Annotation( "GOC:go_curators") "purine base transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:mah") "purine transmembrane transport") -AnnotationAssertion( "purine transport") -AnnotationAssertion( "GO:0006863") -AnnotationAssertion(rdfs:label "purine nucleobase transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (amino acid transport) @@ -56504,7 +21599,6 @@ AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "amino acid transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (lipid transport) @@ -56515,61 +21609,8 @@ AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "lipid transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (intracellular monoatomic ion homeostasis) - -AnnotationAssertion(Annotation( "GOC:mah") "A homeostatic process involved in the maintenance of a steady state level of monoatomic ions within a cell. Monatomic ions (also called simple ions) are ions consisting of exactly one atom.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/24455"^^xsd:anyURI) -AnnotationAssertion( "cellular ion homeostasis") -AnnotationAssertion( "cellular monoatomic ion homeostasis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006873") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "intracellular monoatomic ion homeostasis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (intracellular calcium ion homeostasis) - -AnnotationAssertion(Annotation( "GOC:ceb") Annotation( "GOC:mah") "A homeostatic process involved in the maintenance of a steady state level of calcium ions within a cell.") -AnnotationAssertion( "regulation of calcium ion concentration") -AnnotationAssertion( "cellular calcium ion homeostasis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006874") -AnnotationAssertion(rdfs:label "intracellular calcium ion homeostasis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (intracellular iron ion homeostasis) - -AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:mah") "A homeostatic process involved in the maintenance of a steady state level of iron ions within a cell.") -AnnotationAssertion( "iron homeostasis") -AnnotationAssertion( "cellular iron ion homeostasis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006879") -AnnotationAssertion(rdfs:label "intracellular iron ion homeostasis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (intracellular sodium ion homeostasis) - -AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:mah") "A homeostatic process involved in the maintenance of a steady state level of sodium ions within a cell.") -AnnotationAssertion( "cellular sodium ion homeostasis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006883") -AnnotationAssertion(rdfs:label "intracellular sodium ion homeostasis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (cell volume homeostasis) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:go_curators") Annotation( "GOC:tb") "Any process involved in maintaining the steady state of a cell's volume. The cell's volume refers to the three-dimensional space occupied by a cell.") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "regulation of cell volume") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006884") -AnnotationAssertion(rdfs:label "cell volume homeostasis") -SubClassOf( ) - # Class: (regulation of pH) AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:go_curators") Annotation( "GOC:tb") "Any process involved in the maintenance of an internal equilibrium of hydrogen ions, thereby modulating the internal pH, within an organism or cell.") @@ -56577,22 +21618,8 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:0006885") AnnotationAssertion(rdfs:label "regulation of pH") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (intracellular protein transport) - -AnnotationAssertion(Annotation( "GOC:mah") "The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell.") -AnnotationAssertion( "GO:0032779") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:al") "copper-induced intracellular protein transport") -AnnotationAssertion( "GO:0006886") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "intracellular protein transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (exocytosis) AnnotationAssertion(Annotation( "GOC:mah") Annotation( "ISBN:0716731363") Annotation( "PMID:22323285") "A process of secretion by a cell that results in the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle. Exocytosis can occur either by full fusion, when the vesicle collapses into the plasma membrane, or by a kiss-and-run mechanism that involves the formation of a transient contact, a pore, between a granule (for exemple of chromaffin cells) and the plasma membrane. The latter process most of the time leads to only partial secretion of the granule content. Exocytosis begins with steps that prepare vesicles for fusion with the membrane (tethering and docking) and ends when molecules are secreted from the cell.") @@ -56605,213 +21632,9 @@ AnnotationAssertion( "GO:0006887") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "exocytosis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (post-Golgi vesicle-mediated transport) - -AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:mah") "The directed movement of substances from the Golgi to other parts of the cell, including organelles and the plasma membrane, mediated by small transport vesicles.") -AnnotationAssertion( "post-Golgi transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006892") -AnnotationAssertion(rdfs:label "post-Golgi vesicle-mediated transport") -SubClassOf( ) - -# Class: (Golgi to plasma membrane transport) - -AnnotationAssertion(Annotation( "ISBN:0716731363") "The directed movement of substances from the Golgi to the plasma membrane in transport vesicles that move from the trans-Golgi network to the plasma membrane, where they fuse and release their contents by exocytosis.") -AnnotationAssertion( "Golgi to plasma membrane vesicle-mediated transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006893") -AnnotationAssertion(rdfs:label "Golgi to plasma membrane transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (Golgi to vacuole transport) - -AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of substances from the Golgi to the vacuole.") -AnnotationAssertion( "Golgi to vacuole vesicle-mediated transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006896") -AnnotationAssertion(rdfs:label "Golgi to vacuole transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (endocytosis) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "ISBN:0198506732") Annotation( "ISBN:0716731363") Annotation( "Wikipedia:Endocytosis") "A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a part of the plasma membrane to form a new membrane-bounded vesicle.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/24907"^^xsd:anyURI) -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/25268"^^xsd:anyURI) -AnnotationAssertion( "GO:0016193") -AnnotationAssertion( "GO:0016196") -AnnotationAssertion( "GO:0098701") -AnnotationAssertion( "Wikipedia:Endocytosis") -AnnotationAssertion( "endocytic import into cell") -AnnotationAssertion( "vesicle endocytosis") -AnnotationAssertion( "plasma membrane invagination") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "nonselective vesicle endocytosis") -AnnotationAssertion( "GO:0006897") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "endocytosis") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (vesicle budding from membrane) - -AnnotationAssertion(Annotation( "GOC:jid") Annotation( "GOC:tb") "The evagination of a membrane, resulting in formation of a vesicle.") -AnnotationAssertion( "jl") -AnnotationAssertion( "2013-12-19T15:26:17Z") -AnnotationAssertion( "GO:0006902") -AnnotationAssertion( "GO:1902591") -AnnotationAssertion( "membrane evagination") -AnnotationAssertion( "vesicle biosynthesis") -AnnotationAssertion( "vesicle formation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "nonselective vesicle assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "single organism membrane budding") -AnnotationAssertion( "single-organism membrane budding") -AnnotationAssertion( "vesicle budding") -AnnotationAssertion( "GO:0006900") -AnnotationAssertion(rdfs:label "vesicle budding from membrane") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (vesicle targeting) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "PMID:17335816") "The process in which vesicles are directed to specific destination membranes. Targeting involves coordinated interactions among cytoskeletal elements (microtubules or actin filaments), motor proteins, molecules at the vesicle membrane and target membrane surfaces, and vesicle cargo.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006903") -AnnotationAssertion(rdfs:label "vesicle targeting") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (vesicle fusion) - -AnnotationAssertion(Annotation( "GOC:jid") "Fusion of the membrane of a transport vesicle with its target membrane.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006906") -AnnotationAssertion(rdfs:label "vesicle fusion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (phagocytosis) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "A vesicle-mediated transport process that results in the engulfment of external particulate material by phagocytes and their delivery to the lysosome. The particles are initially contained within phagocytic vacuoles (phagosomes), which then fuse with primary lysosomes to effect digestion of the particles.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/24907"^^xsd:anyURI) -AnnotationAssertion( ) -AnnotationAssertion( "Wikipedia:Phagocytosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006909") -AnnotationAssertion(rdfs:label "phagocytosis") -SubClassOf( ) -SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) -DisjointClasses( ObjectSomeValuesFrom( )) - -# Class: (nucleocytoplasmic transport) - -AnnotationAssertion(Annotation( "GOC:go_curators") "The directed movement of molecules between the nucleus and the cytoplasm.") -AnnotationAssertion( "GO:0000063") -AnnotationAssertion( "nucleocytoplasmic shuttling") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006913") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "Note that transport through the nuclear pore complex is not transmembrane because the nuclear membrane is a double membrane, and is not traversed.") -AnnotationAssertion(rdfs:label "nucleocytoplasmic transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (apoptotic process) - -AnnotationAssertion(Annotation( "GOC:cjm") Annotation( "GOC:dhl") Annotation( "GOC:ecd") Annotation( "GOC:go_curators") Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:tb") Annotation( "ISBN:0198506732") Annotation( "PMID:18846107") Annotation( "PMID:21494263") "A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "GO:0006917") -AnnotationAssertion( "GO:0008632") -AnnotationAssertion( "cell suicide") -AnnotationAssertion( "cellular suicide") -AnnotationAssertion( "Wikipedia:Apoptosis") -AnnotationAssertion(Annotation( "GOC:sl") "apoptotic cell death") -AnnotationAssertion( "apoptotic programmed cell death") -AnnotationAssertion( "programmed cell death by apoptosis") -AnnotationAssertion( "activation of apoptosis") -AnnotationAssertion( "apoptosis") -AnnotationAssertion( "apoptosis signaling") -AnnotationAssertion(Annotation( "GOC:add") "apoptotic program") -AnnotationAssertion( "type I programmed cell death") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "apoptosis activator activity") -AnnotationAssertion( "caspase-dependent programmed cell death") -AnnotationAssertion( "commitment to apoptosis") -AnnotationAssertion( "induction of apoptosis") -AnnotationAssertion( "induction of apoptosis by p53") -AnnotationAssertion( "signaling (initiator) caspase activity") -AnnotationAssertion( "GO:0006915") -AnnotationAssertion(rdfs:label "apoptotic process") -SubClassOf( ) -SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) -SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) -SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) -DisjointClasses( ObjectSomeValuesFrom( )) -DisjointClasses( ObjectSomeValuesFrom( )) - -# Class: (cellular component disassembly involved in execution phase of apoptosis) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mah") Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:tb") "The breakdown of structures such as organelles, proteins, or other macromolecular structures during apoptosis.") -AnnotationAssertion( "cellular component disassembly involved in apoptotic process") -AnnotationAssertion( "disassembly of cell structures") -AnnotationAssertion( "cellular component disassembly involved in apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006921") -AnnotationAssertion(rdfs:label "cellular component disassembly involved in execution phase of apoptosis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (inflammatory cell apoptotic process) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "GOC:mtg_apoptosis") "Any apoptotic process in an inflammatory cell, any cell participating in the inflammatory response to a foreign substance e.g. neutrophil, macrophage.") -AnnotationAssertion( "apoptosis of inflammatory cells") -AnnotationAssertion( "inflammatory cell programmed cell death by apoptosis") -AnnotationAssertion( "killing of inflammatory cells") -AnnotationAssertion( "programmed cell death of inflammatory cells by apoptosis") -AnnotationAssertion( "programmed cell death, inflammatory cells") -AnnotationAssertion( "inflammatory cell apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006925") -AnnotationAssertion(rdfs:label "inflammatory cell apoptotic process") -SubClassOf( ) - -# Class: (chemotaxis) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "The directed movement of a motile cell or organism, or the directed growth of a cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).") -AnnotationAssertion( "Wikipedia:Chemotaxis") -AnnotationAssertion( "taxis in response to chemical stimulus") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006935") -AnnotationAssertion(rdfs:label "chemotaxis") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (muscle contraction) AnnotationAssertion(Annotation( "GOC:ef") Annotation( "GOC:mtg_muscle") Annotation( "ISBN:0198506732") "A process in which force is generated within muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis.") @@ -56823,15 +21646,6 @@ AnnotationAssertion(rdfs:label "musc SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (regulation of muscle contraction) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of muscle contraction.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006937") -AnnotationAssertion(rdfs:label "regulation of muscle contraction") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - # Class: (smooth muscle contraction) AnnotationAssertion(Annotation( "GOC:ef") Annotation( "GOC:jl") Annotation( "GOC:mtg_muscle") Annotation( "ISBN:0198506732") "A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Smooth muscle differs from striated muscle in the much higher actin/myosin ratio, the absence of conspicuous sarcomeres and the ability to contract to a much smaller fraction of its resting length.") @@ -56839,18 +21653,8 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0006939") AnnotationAssertion(rdfs:label "smooth muscle contraction") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (regulation of smooth muscle contraction) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of smooth muscle contraction.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006940") -AnnotationAssertion(rdfs:label "regulation of smooth muscle contraction") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - # Class: (striated muscle contraction) AnnotationAssertion(Annotation( "GOC:jl") Annotation( "GOC:mtg_muscle") Annotation( "ISBN:0198506732") "A process in which force is generated within striated muscle tissue, resulting in the shortening of the muscle. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Striated muscle is a type of muscle in which the repeating units (sarcomeres) of the contractile myofibrils are arranged in registry throughout the cell, resulting in transverse or oblique striations observable at the level of the light microscope.") @@ -56861,27 +21665,6 @@ AnnotationAssertion(rdfs:label "stri SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (regulation of striated muscle contraction) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of striated muscle contraction.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006942") -AnnotationAssertion(rdfs:label "regulation of striated muscle contraction") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (syncytium formation) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "The formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane. Syncytia are normally derived from single cells that fuse or fail to complete cell division.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0006949") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "syncytium formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - # Class: (response to stress) AnnotationAssertion(Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).") @@ -56945,415 +21728,6 @@ AnnotationAssertion( "humoral immune response") SubClassOf( ) -# Class: (organelle organization) - -AnnotationAssertion(Annotation( "GOC:mah") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an organelle within a cell. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.") -AnnotationAssertion( "jl") -AnnotationAssertion( "2013-12-19T15:25:51Z") -AnnotationAssertion( "GO:1902589") -AnnotationAssertion( "organelle organisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "single organism organelle organization") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:jl") Annotation( "GOC:mah") "organelle organization and biogenesis") -AnnotationAssertion( "single-organism organelle organization") -AnnotationAssertion( "GO:0006996") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "organelle organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (nucleus organization) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:ems") Annotation( "GOC:jl") Annotation( "GOC:mah") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nucleus.") -AnnotationAssertion( "GO:0048287") -AnnotationAssertion( "nuclear organisation") -AnnotationAssertion( "nuclear organization") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "nuclear morphology") -AnnotationAssertion(Annotation( "GOC:mah") "nuclear organization and biogenesis") -AnnotationAssertion(Annotation( "GOC:mah") "nucleus organization and biogenesis") -AnnotationAssertion( "GO:0006997") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "nucleus organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (nuclear envelope organization) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:ems") Annotation( "GOC:jl") Annotation( "GOC:mah") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear envelope.") -AnnotationAssertion(Annotation( "GOC:mah") "nuclear envelope organisation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:mah") "nuclear envelope organization and biogenesis") -AnnotationAssertion( "GO:0006998") -AnnotationAssertion(rdfs:label "nuclear envelope organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (nucleolus organization) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GOC:jl") Annotation( "GOC:mah") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nucleolus.") -AnnotationAssertion( "nucleolus organisation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:mah") "nucleolus organization and biogenesis") -AnnotationAssertion( "GO:0007000") -AnnotationAssertion(rdfs:label "nucleolus organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (plasma membrane organization) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:jl") Annotation( "GOC:mah") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the plasma membrane.") -AnnotationAssertion( "plasma membrane organisation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:mah") "plasma membrane organization and biogenesis") -AnnotationAssertion( "GO:0007009") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "plasma membrane organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cytoskeleton organization) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:jl") Annotation( "GOC:mah") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures.") -AnnotationAssertion( "cytoskeleton organisation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:mah") "cytoskeletal organization and biogenesis") -AnnotationAssertion( "cytoskeletal regulator activity") -AnnotationAssertion(Annotation( "GOC:mah") "cytoskeleton organization and biogenesis") -AnnotationAssertion( "GO:0007010") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "cytoskeleton organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (actin filament organization) - -AnnotationAssertion(Annotation( "GOC:mah") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments. Includes processes that control the spatial distribution of actin filaments, such as organizing filaments into meshworks, bundles, or other structures, as by cross-linking.") -AnnotationAssertion( "actin filament organisation") -AnnotationAssertion( "regulation of actin filament localization") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0007015") -AnnotationAssertion(rdfs:label "actin filament organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (microtubule-based process) - -AnnotationAssertion(Annotation( "GOC:mah") "Any cellular process that depends upon or alters the microtubule cytoskeleton, that part of the cytoskeleton comprising microtubules and their associated proteins.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/19809"^^xsd:anyURI) -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0007017") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "microtubule-based process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (microtubule-based movement) - -AnnotationAssertion(Annotation( "GOC:cjm") Annotation( "ISBN:0815316194") "A microtubule-based process that results in the movement of organelles, other microtubules, or other cellular components. Examples include motor-driven movement along microtubules and movement driven by polymerization or depolymerization of microtubules.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0007018") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "microtubule-based movement") -SubClassOf( ) - -# Class: (microtubule depolymerization) - -AnnotationAssertion(Annotation( "ISBN:0815316194") "The removal of tubulin heterodimers from one or both ends of a microtubule.") -AnnotationAssertion( "microtubule disassembly") -AnnotationAssertion( "microtubule shortening") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "microtubule catastrophe") -AnnotationAssertion( "microtubule depolymerization during nuclear congression") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0007019") -AnnotationAssertion(rdfs:label "microtubule depolymerization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (microtubule nucleation) - -AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0815316194") Annotation( "PMID:12517712") "The process in which tubulin alpha-beta heterodimers begin aggregation to form an oligomeric tubulin structure (a microtubule seed). Microtubule nucleation is the initiating step in the formation of a microtubule in the absence of any existing microtubules ('de novo' microtubule formation).") -AnnotationAssertion( "Wikipedia:Microtubule_nucleation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0007020") -AnnotationAssertion(rdfs:label "microtubule nucleation") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (negative regulation of microtubule depolymerization) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "ISBN:0815316194") "Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule depolymerization; prevention of depolymerization of a microtubule can result from binding by 'capping' at the plus end (e.g. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing drug such as taxol.") -AnnotationAssertion( "down regulation of microtubule depolymerization") -AnnotationAssertion( "down-regulation of microtubule depolymerization") -AnnotationAssertion( "downregulation of microtubule depolymerization") -AnnotationAssertion( "microtubule stabilization") -AnnotationAssertion( "negative regulation of microtubule disassembly") -AnnotationAssertion( "inhibition of microtubule depolymerization") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "microtubule rescue") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "negative regulation of microtubule catastrophe") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0007026") -AnnotationAssertion(rdfs:label "negative regulation of microtubule depolymerization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of axonemal microtubule depolymerization) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of the depolymerization of the specialized microtubules of the axoneme.") -AnnotationAssertion( "axonemal microtubule stabilization") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") "negative regulation of microtubule depolymerization in axoneme") -AnnotationAssertion( "GO:0007027") -AnnotationAssertion(rdfs:label "negative regulation of axonemal microtubule depolymerization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cytoplasm organization) - -AnnotationAssertion(Annotation( "GOC:curators") Annotation( "GOC:dph") Annotation( "GOC:jl") Annotation( "GOC:mah") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the cytoplasm. The cytoplasm is all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.") -AnnotationAssertion( "cytoplasm organisation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:mah") "cytoplasm organization and biogenesis") -AnnotationAssertion( "GO:0007028") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "cytoplasm organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (Golgi organization) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:jl") Annotation( "GOC:mah") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the Golgi apparatus.") -AnnotationAssertion( "Golgi apparatus organization") -AnnotationAssertion( "Golgi organisation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:mah") "Golgi organization and biogenesis") -AnnotationAssertion( "GO:0007030") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "Golgi organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (vacuole organization) - -AnnotationAssertion(Annotation( "GOC:mah") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vacuole.") -AnnotationAssertion( "GO:0044086") -AnnotationAssertion( "vacuole organisation") -AnnotationAssertion(Annotation( "GOC:mah") "vacuolar assembly") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:mah") "vacuole biogenesis") -AnnotationAssertion(Annotation( "GOC:mah") "vacuole organization and biogenesis") -AnnotationAssertion( "GO:0007033") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "vacuole organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (vacuolar transport) - -AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of substances into, out of or within a vacuole.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0007034") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "vacuolar transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (vacuolar calcium ion homeostasis) - -AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:mah") "Any process involved in the maintenance of an internal steady state of calcium ions in the vacuole or between a vacuole and its surroundings.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0007036") -AnnotationAssertion(rdfs:label "vacuolar calcium ion homeostasis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (protein catabolic process in the vacuole) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:vw") "The chemical reactions and pathways resulting in the breakdown of a protein in the vacuole, usually by the action of vacuolar proteases.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "vacuolar protein breakdown") -AnnotationAssertion( "vacuolar protein catabolic process") -AnnotationAssertion( "vacuolar protein catabolism") -AnnotationAssertion( "vacuolar protein degradation") -AnnotationAssertion( "GO:0007039") -AnnotationAssertion(rdfs:label "protein catabolic process in the vacuole") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (lysosome organization) - -AnnotationAssertion(Annotation( "GOC:mah") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lysosome. A lysosome is a cytoplasmic, membrane-bounded organelle that is found in most animal cells and that contains a variety of hydrolases.") -AnnotationAssertion( "lysosome organisation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:mah") "lysosome organization and biogenesis") -AnnotationAssertion( "GO:0007040") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "lysosome organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (lysosomal transport) - -AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of substances into, out of or within a lysosome.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0007041") -AnnotationAssertion(rdfs:label "lysosomal transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (cell-cell junction assembly) - -AnnotationAssertion(Annotation( "GOC:ai") "The aggregation, arrangement and bonding together of a set of components to form a junction between cells.") -AnnotationAssertion( "intercellular junction assembly") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0007043") -AnnotationAssertion(rdfs:label "cell-cell junction assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cell cycle) - -AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "GOC:mtg_cell_cycle") "The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division.") -AnnotationAssertion( "Wikipedia:Cell_cycle") -AnnotationAssertion( "cell-division cycle") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0007049") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "cell cycle") -SubClassOf( ) - -# Class: (chromosome segregation) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "GOC:mah") Annotation( "GOC:mtg_cell_cycle") Annotation( "GOC:vw") "The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. In eukaryotes, chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles.") -AnnotationAssertion( "Wikipedia:Chromosome_segregation") -AnnotationAssertion( "chromosome division") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "chromosome transmission") -AnnotationAssertion( "GO:0007059") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "chromosome segregation") -SubClassOf( ) -SubClassOf( ) - -# Class: (mitotic chromosome condensation) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "ISBN:0815316194") "The cell cycle process in which chromatin structure is compacted prior to and during mitosis in eukaryotic cells.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0007076") -AnnotationAssertion(rdfs:label "mitotic chromosome condensation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (mitotic nuclear membrane disassembly) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "PMID:32848252") "The mitotic cell cycle process in which the controlled partial or complete breakdown of the nuclear membranes during occurs during mitosis.") -AnnotationAssertion( "NEB") -AnnotationAssertion( "local NEB") -AnnotationAssertion( "nuclear envelope breakdown") -AnnotationAssertion( "mitotic nuclear envelope breakdown") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "mitotic nuclear envelope catabolism") -AnnotationAssertion( "mitotic nuclear envelope degradation") -AnnotationAssertion( "mitotic nuclear envelope disassembly") -AnnotationAssertion( "GO:0007077") -AnnotationAssertion(rdfs:label "mitotic nuclear membrane disassembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of mitotic nuclear division) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of mitosis.") -AnnotationAssertion( "regulation of mitosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0007088") -AnnotationAssertion(rdfs:label "regulation of mitotic nuclear division") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (nuclear migration) - -AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of the nucleus to a specific location within a cell.") -AnnotationAssertion( "GO:0040023") -AnnotationAssertion( "establishment of position of nucleus") -AnnotationAssertion( "nuclear movement") -AnnotationAssertion( "nuclear positioning") -AnnotationAssertion( "nucleus migration") -AnnotationAssertion( "nucleus positioning") -AnnotationAssertion( "positioning of nucleus") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "establishment of cell nucleus localization") -AnnotationAssertion( "establishment of localization of nucleus") -AnnotationAssertion(Annotation( "GOC:mah") "establishment of nucleus localisation") -AnnotationAssertion( "establishment of nucleus localization") -AnnotationAssertion( "GO:0007097") -AnnotationAssertion(rdfs:label "nuclear migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (endomitotic cell cycle) - -AnnotationAssertion(Annotation( "GOC:curators") Annotation( "GOC:dos") Annotation( "GOC:expert_vm") "A mitotic cell cycle in which chromosomes are replicated and sister chromatids separate, but spindle formation, nuclear membrane breakdown and nuclear division do not occur, resulting in an increased number of chromosomes in the cell.") -AnnotationAssertion( "Wikipedia:Mitosis#Endomitosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "endomitosis") -AnnotationAssertion( "GO:0007113") -AnnotationAssertion(rdfs:comment "Note that this term should not be confused with 'abortive mitotic cell cycle ; GO:0033277'. Although abortive mitosis is sometimes called endomitosis, GO:0033277 refers to a process in which a mitotic spindle forms and chromosome separation begins.") -AnnotationAssertion(rdfs:label "endomitotic cell cycle") -SubClassOf( ) - -# Class: (meiosis II) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mah") Annotation( "ISBN:0198547684") "The second nuclear division of meiosis, in which the two chromatids in each chromosome are separated, resulting in four daughter nuclei from the two nuclei produced in meiosis II.") -AnnotationAssertion( "Wikipedia:Meiosis#Meiosis_II") -AnnotationAssertion( "meiosis II nuclear division") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0007135") -AnnotationAssertion(rdfs:label "meiosis II") -SubClassOf( ) -SubClassOf( ) - -# Class: (male meiotic nuclear division) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mah") Annotation( "GOC:vw") "A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the male germline.") -AnnotationAssertion( ) -AnnotationAssertion( "male nuclear division") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "male meiosis") -AnnotationAssertion( "GO:0007140") -AnnotationAssertion(rdfs:label "male meiotic nuclear division") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) -DisjointClasses( ObjectSomeValuesFrom( )) - -# Class: (male meiosis II) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mah") "A cell cycle process comprising the steps by which a cell progresses through male meiosis II, the second meiotic division in the male germline.") -AnnotationAssertion( "male meiosis II nuclear division") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0007142") -AnnotationAssertion(rdfs:label "male meiosis II") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ) - # Class: (female meiotic nuclear division) AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:ems") Annotation( "GOC:mah") Annotation( "GOC:vw") "A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the female germline.") @@ -57364,22 +21738,11 @@ AnnotationAssertion( "GO:0007143") AnnotationAssertion(rdfs:comment "Note that female germ lines can be found in female or hermaphroditic organisms, so this term can be used to annotate gene products from hermaphrodites such as those of C. elegans. See also the biological process term 'meiotic nuclear division; GO:0140013'.") AnnotationAssertion(rdfs:label "female meiotic nuclear division") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) DisjointClasses( ObjectSomeValuesFrom( )) -# Class: (female meiosis II) - -AnnotationAssertion(Annotation( "GOC:mah") "The cell cycle process in which the second meiotic division occurs in the female germline.") -AnnotationAssertion( "female meiosis II nuclear division") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0007147") -AnnotationAssertion(rdfs:label "female meiosis II") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ) - # Class: (cell communication) AnnotationAssertion(Annotation( "GOC:mah") "Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.") @@ -57391,239 +21754,6 @@ AnnotationAssertion( "cell communication") SubClassOf( ) -# Class: (cell adhesion) - -AnnotationAssertion(Annotation( "GOC:hb") Annotation( "GOC:pf") "The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.") -AnnotationAssertion( "dos") -AnnotationAssertion( "2014-04-15T15:59:10Z") -AnnotationAssertion( "GO:0098602") -AnnotationAssertion( "Wikipedia:Cell_adhesion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "cell adhesion molecule activity") -AnnotationAssertion( "single organism cell adhesion") -AnnotationAssertion( "GO:0007155") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "cell adhesion") -SubClassOf( ) - -# Class: (leukocyte cell-cell adhesion) - -AnnotationAssertion(Annotation( "GOC:go_curators") "The attachment of a leukocyte to another cell via adhesion molecules.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "leukocyte adhesion") -AnnotationAssertion( "leukocyte cell adhesion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0007159") -AnnotationAssertion(rdfs:label "leukocyte cell-cell adhesion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) -SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) -SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) -SubClassOf( ObjectAllValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) -DisjointClasses( ObjectSomeValuesFrom( )) -DisjointClasses( ObjectSomeValuesFrom( )) - -# Class: (negative regulation of cell adhesion) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of cell adhesion.") -AnnotationAssertion( "down regulation of cell adhesion") -AnnotationAssertion( "down-regulation of cell adhesion") -AnnotationAssertion( "downregulation of cell adhesion") -AnnotationAssertion( "inhibition of cell adhesion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "cell adhesion receptor inhibitor activity") -AnnotationAssertion( "GO:0007162") -AnnotationAssertion(rdfs:label "negative regulation of cell adhesion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (establishment or maintenance of cell polarity) - -AnnotationAssertion(Annotation( "GOC:mah") "Any cellular process that results in the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns.") -AnnotationAssertion( "GO:0030012") -AnnotationAssertion( "GO:0030467") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:vw") "cell polarity") -AnnotationAssertion( "establishment and/or maintenance of cell polarity") -AnnotationAssertion( "establishment and/or maintenance of cell polarization") -AnnotationAssertion( "GO:0007163") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "establishment or maintenance of cell polarity") -SubClassOf( ) - -# Class: (signal transduction) - -AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "GOC:mtg_signaling_feb11") "The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.") -AnnotationAssertion( "GO:0023014") -AnnotationAssertion( "GO:0023015") -AnnotationAssertion( "GO:0023016") -AnnotationAssertion( "GO:0023033") -AnnotationAssertion( "GO:0023045") -AnnotationAssertion( "Wikipedia:Signal_transduction") -AnnotationAssertion( "signal transduction by cis-phosphorylation") -AnnotationAssertion( "signal transduction by conformational transition") -AnnotationAssertion( "signal transduction by protein phosphorylation") -AnnotationAssertion( "signal transduction by trans-phosphorylation") -AnnotationAssertion( "signaling cascade") -AnnotationAssertion( "signalling cascade") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "signaling pathway") -AnnotationAssertion(Annotation( "GOC:mah") "signalling pathway") -AnnotationAssertion( "GO:0007165") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "Note that signal transduction is defined broadly to include a ligand interacting with a receptor, downstream signaling steps and a response being triggered. A change in form of the signal in every step is not necessary. Note that in many cases the end of this process is regulation of the initiation of transcription. Note that specific transcription factors may be annotated to this term, but core/general transcription machinery such as RNA polymerase should not.") -AnnotationAssertion(rdfs:label "signal transduction") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cell surface receptor signaling pathway) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:mah") Annotation( "GOC:pr") Annotation( "GOC:signaling") "The series of molecular signals initiated by activation of a receptor on the surface of a cell. The pathway begins with binding of an extracellular ligand to a cell surface receptor, or for receptors that signal in the absence of a ligand, by ligand-withdrawal or the activity of a constitutively active receptor. The pathway ends with regulation of a downstream cellular process, e.g. transcription.") -AnnotationAssertion( "cell surface receptor linked signal transduction") -AnnotationAssertion(Annotation( "GOC:bf") "cell surface receptor linked signaling pathway") -AnnotationAssertion(Annotation( "GOC:mah") "cell surface receptor linked signalling pathway") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0007166") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "cell surface receptor signaling pathway") -SubClassOf( ) - -# Class: (enzyme-linked receptor protein signaling pathway) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:signaling") Annotation( "ISBN:0815316194") "The series of molecular signals initiated by an extracellular ligand binding to a receptor on the surface of the target cell, where the receptor possesses catalytic activity or is closely associated with an enzyme such as a protein kinase, and ending with the regulation of a downstream cellular process, e.g. transcription.") -AnnotationAssertion( "enzyme linked receptor protein signaling pathway") -AnnotationAssertion( "enzyme linked receptor protein signalling pathway") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0007167") -AnnotationAssertion(rdfs:label "enzyme-linked receptor protein signaling pathway") -SubClassOf( ) - -# Class: (transmembrane receptor protein tyrosine kinase signaling pathway) - -AnnotationAssertion(Annotation( "GOC:ceb") Annotation( "GOC:signaling") "The series of molecular signals initiated by an extracellular ligand binding to a receptor on the surface of the target cell where the receptor possesses tyrosine kinase activity, and ending with the regulation of a downstream cellular process, e.g. transcription.") -AnnotationAssertion( "transmembrane receptor protein tyrosine kinase signalling pathway") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0007169") -AnnotationAssertion(rdfs:label "transmembrane receptor protein tyrosine kinase signaling pathway") -SubClassOf( ) - -# Class: (G protein-coupled receptor signaling pathway) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:mah") Annotation( "PMID:16902576") Annotation( "PMID:24568158") Annotation( "Wikipedia:G_protein-coupled_receptor") "The series of molecular signals initiated by a ligand binding to its receptor, in which the activated receptor promotes the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, and ends with regulation of a downstream cellular process. The pathway can start from the plasma membrane, Golgi or nuclear membrane.") -AnnotationAssertion( "GO:0038042") -AnnotationAssertion( "G protein coupled receptor protein signaling pathway") -AnnotationAssertion( "G protein coupled receptor protein signalling pathway") -AnnotationAssertion( "G-protein coupled receptor protein signal transduction") -AnnotationAssertion(Annotation( "GOC:bf") "G-protein coupled receptor protein signaling pathway") -AnnotationAssertion( "G-protein coupled receptor signalling pathway") -AnnotationAssertion( "G-protein-coupled receptor protein signalling pathway") -AnnotationAssertion( "GPCR signaling pathway") -AnnotationAssertion( "GPCR signalling pathway") -AnnotationAssertion(Annotation( "GOC:bf") "G-protein coupled receptor signaling pathway via GPCR dimer") -AnnotationAssertion( "dimeric G-protein coupled receptor signaling pathway") -AnnotationAssertion(Annotation( "GOC:mah") "dimeric G-protein coupled receptor signalling pathway") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0007186") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "G protein-coupled receptor signaling pathway") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (serotonin receptor signaling pathway) - -AnnotationAssertion(Annotation( "GOC:mah") "The series of molecular signals generated as a consequence of a serotonin receptor binding to one of its physiological ligands.") -AnnotationAssertion( "serotonin receptor signalling pathway") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0007210") -AnnotationAssertion(rdfs:label "serotonin receptor signaling pathway") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (G protein-coupled acetylcholine receptor signaling pathway) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "ISBN:0815316194") "A G protein-coupled receptor signaling pathway initiated by a ligand binding to an acetylcholine receptor on the surface of a target cell, and ends with regulation of a downstream cellular process, e.g. transcription.") -AnnotationAssertion( "G-protein coupled acetylcholine receptor signaling pathway") -AnnotationAssertion( "acetylcholine receptor signalling, muscarinic pathway") -AnnotationAssertion(Annotation( "GOC:bf") "muscarinic acetylcholine receptor signaling pathway") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0007213") -AnnotationAssertion(rdfs:label "G protein-coupled acetylcholine receptor signaling pathway") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (gamma-aminobutyric acid signaling pathway) - -AnnotationAssertion(Annotation( "GOC:mah") "The series of molecular signals generated by the binding of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms, to its receptor on the surface of a target cell.") -AnnotationAssertion( "4-aminobutanoate signaling pathway") -AnnotationAssertion( "4-aminobutanoate signalling pathway") -AnnotationAssertion( "4-aminobutyrate signaling pathway") -AnnotationAssertion( "4-aminobutyrate signalling pathway") -AnnotationAssertion( "GABA signaling pathway") -AnnotationAssertion( "GABA signalling pathway") -AnnotationAssertion( "gamma-aminobutyric acid signalling pathway") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0007214") -AnnotationAssertion(rdfs:label "gamma-aminobutyric acid signaling pathway") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (glutamate receptor signaling pathway) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:signaling") Annotation( "PMID:9131252") "The series of molecular signals initiated by the binding of glutamate to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.") -AnnotationAssertion(Annotation( "GOC:bf") "glutamate signaling pathway") -AnnotationAssertion( "glutamate signalling pathway") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0007215") -AnnotationAssertion(rdfs:label "glutamate receptor signaling pathway") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (G protein-coupled glutamate receptor signaling pathway) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:signaling") Annotation( "PMID:9131252") "A G protein-coupled receptor signaling pathway initiated by glutamate binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process.") -AnnotationAssertion( "G-protein coupled glutamate receptor signaling pathway") -AnnotationAssertion(Annotation( "GOC:bf") "metabotropic glutamate receptor signaling pathway") -AnnotationAssertion( "metabotropic glutamate receptor signalling pathway") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0007216") -AnnotationAssertion(rdfs:label "G protein-coupled glutamate receptor signaling pathway") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (neuropeptide signaling pathway) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "ISBN:0815316194") "A G protein-coupled receptor signaling pathway initiated by a neuropeptide binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process.") -AnnotationAssertion( ) -AnnotationAssertion( "neuropeptide signalling pathway") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0007218") -AnnotationAssertion(rdfs:label "neuropeptide signaling pathway") -SubClassOf( ) -SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) -DisjointClasses( ObjectSomeValuesFrom( )) - # Class: (cell-cell signaling) AnnotationAssertion(Annotation( "GOC:dos") Annotation( "GOC:mah") "Any process that mediates the transfer of information from one cell to another. This process includes signal transduction in the receiving cell and, where applicable, release of a ligand and any processes that actively facilitate its transport and presentation to the receiving cell. Examples include signaling via soluble ligands, via cell adhesion molecules and via gap junctions.") @@ -57663,41 +21793,10 @@ AnnotationAssertion( ) AnnotationAssertion(rdfs:comment "A neurotransmitter is any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell. Among the many substances that have the properties of a neurotransmitter are acetylcholine, noradrenaline, adrenaline, dopamine, glycine, gamma-aminobutyrate, glutamic acid, substance P, enkephalins, endorphins and serotonin.") AnnotationAssertion(rdfs:label "neurotransmitter secretion") -SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (synaptic transmission, cholinergic) - -AnnotationAssertion(Annotation( "GOC:dos") Annotation( "Wikipedia:Cholinergic") "The vesicular release of acetylcholine from a presynapse, across a chemical synapse, the subsequent activation of dopamine receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.") -AnnotationAssertion( "cholinergic synaptic transmission") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0007271") -AnnotationAssertion(rdfs:label "synaptic transmission, cholinergic") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (ensheathment of neurons) - -AnnotationAssertion(Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:tb") "The process in which glial cells envelop neuronal cell bodies and/or axons to form an insulating layer. This can take the form of myelinating or non-myelinating ensheathment.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "ionic insulation of neurons by glial cells") -AnnotationAssertion( "GO:0007272") -AnnotationAssertion(rdfs:label "ensheathment of neurons") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (neuromuscular synaptic transmission) - -AnnotationAssertion(Annotation( "GOC:dos") Annotation( "GOC:jl") Annotation( "MeSH:D009435") "The process of synaptic transmission from a neuron to a muscle, across a synapse.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0007274") -AnnotationAssertion(rdfs:label "neuromuscular synaptic transmission") -SubClassOf( ) - # Class: (multicellular organism development) AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:ems") Annotation( "GOC:isa_complete") Annotation( "GOC:tb") "The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).") @@ -57709,7 +21808,6 @@ AnnotationAssertion( ) AnnotationAssertion(rdfs:comment "Note that this term was 'developmental process'.") AnnotationAssertion(rdfs:label "multicellular organism development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ) @@ -57739,7 +21837,6 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0007281") AnnotationAssertion(rdfs:label "germ cell development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ) @@ -57756,28 +21853,6 @@ AnnotationAssertion(rdfs:label "sper SubClassOf( ) SubClassOf( ) -# Class: (spermatogonial cell division) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:pr") Annotation( "ISBN:0879694238") "The mitotic divisions of the primary spermatogonial cell (a primordial male germ cell) to form secondary spermatogonia (primary spermatocytes).") -AnnotationAssertion( "spermatogonium division") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0007284") -AnnotationAssertion(rdfs:comment "See also the Cell Ontology terms 'spermatogonium ; CL:0000020' and 'primary spermatocyte ; CL:0000656'.") -AnnotationAssertion(rdfs:label "spermatogonial cell division") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (primary spermatocyte growth) - -AnnotationAssertion(Annotation( "GOC:jid") Annotation( "ISBN:0879694238") "The phase of growth and gene expression that male germ cells undergo as they enter the spermatocyte stage. The cells grow in volume and transcribe most of the gene products needed for the morphological events that follow meiosis.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0007285") -AnnotationAssertion(rdfs:label "primary spermatocyte growth") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (spermatid development) AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:go_curators") "The process whose specific outcome is the progression of a spermatid over time, from its formation to the mature structure.") @@ -57787,32 +21862,9 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0007286") AnnotationAssertion(rdfs:label "spermatid development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (sperm axoneme assembly) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:cilia") Annotation( "ISBN:0198547684") "The assembly and organization of the sperm flagellar axoneme, the bundle of microtubules and associated proteins that forms the core of the eukaryotic sperm flagellum, and is responsible for movement.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0007288") -AnnotationAssertion(rdfs:label "sperm axoneme assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (spermatid nucleus differentiation) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:dph") Annotation( "GOC:jl") Annotation( "GOC:mah") "The specialization of the spermatid nucleus during the development of a spermatid into a mature male gamete competent for fertilization.") -AnnotationAssertion( "spermatid nuclear differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0007289") -AnnotationAssertion(rdfs:comment "See also the Cell Ontology term 'spermatid ; CL:0000018'.") -AnnotationAssertion(rdfs:label "spermatid nucleus differentiation") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (female gamete generation) AnnotationAssertion(Annotation( "GOC:dph") Annotation( "ISBN:0198506732") "Generation of the female gamete; specialised haploid cells produced by meiosis and along with a male gamete takes part in sexual reproduction.") @@ -57821,109 +21873,6 @@ AnnotationAssertion( "female gamete generation") SubClassOf( ) -# Class: (germarium-derived egg chamber formation) - -AnnotationAssertion(Annotation( "GOC:mtg_sensu") Annotation( "ISBN:0879694238") "Construction of a stage-1 egg chamber in the anterior part of the germarium, from the progeny of germ-line and somatic stem cells. An example of this is found in Drosophila melanogaster.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0007293") -AnnotationAssertion(rdfs:label "germarium-derived egg chamber formation") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - -# Class: (follicle cell of egg chamber migration) - -AnnotationAssertion(Annotation( "GOC:mtg_sensu") Annotation( "PMID:10822261") "The directed movement of an ovarian follicle cell that takes place during oogenesis. During egg chamber formation, follicle cells migrate to envelop the germ-line cysts and move in between cysts. At stage 10B, follicle cells migrate centripetally between the nurse cells and the oocyte, enclosing the anterior of the egg. An example of this is found in Drosophila melanogaster.") -AnnotationAssertion( "follicle cell migration") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0007297") -AnnotationAssertion(rdfs:label "follicle cell of egg chamber migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - -# Class: (chorion-containing eggshell formation) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:mtg_sensu") "The construction of a chorion-containing eggshell. An example of this is found in Drosophila melanogaster.") -AnnotationAssertion( "eggshell formation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0007304") -AnnotationAssertion(rdfs:label "chorion-containing eggshell formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (vitelline membrane formation involved in chorion-containing eggshell formation) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:mtg_sensu") "Construction of the vitelline membrane portion of a chorion-containing eggshell. An example of this is found in Drosophila melanogaster.") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "vitelline membrane formation in chorion-containing eggshell") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0007305") -AnnotationAssertion(rdfs:label "vitelline membrane formation involved in chorion-containing eggshell formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (egg chorion assembly) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_sensu") Annotation( "GOC:tb") Annotation( "ISBN:0879694238") Annotation( "PMID:24804966") "Construction of the chorion portion of the egg, which is a protective, noncellular membrane that surrounds the eggs of various animals including insects and fish.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/22603"^^xsd:anyURI) -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "eggshell chorion formation") -AnnotationAssertion( "insect chorion formation") -AnnotationAssertion( "GO:0007306") -AnnotationAssertion(rdfs:label "egg chorion assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (oocyte construction) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:ems") Annotation( "GOC:mtg_sensu") Annotation( "GOC:tb") Annotation( "ISBN:0198506732") "The synthesis, deposition, and organization of the materials in a cell of an ovary; where the cell can then undergo meiosis and form an ovum. An example of this is found in Drosophila melanogaster.") -AnnotationAssertion( "GO:0048110") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "oocyte arrangement") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0007308") -AnnotationAssertion(rdfs:label "oocyte construction") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (oocyte axis specification) - -AnnotationAssertion(Annotation( "GOC:mtg_sensu") Annotation( "ISBN:0879694238") "The establishment, maintenance and elaboration of an axis in the oocyte. An example of this is found in Drosophila melanogaster.") -AnnotationAssertion( "GO:0048111") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "oocyte axis determination") -AnnotationAssertion( "GO:0007309") -AnnotationAssertion(rdfs:label "oocyte axis specification") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (oocyte anterior/posterior axis specification) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_sensu") Annotation( "GOC:tb") Annotation( "ISBN:0879694238") "Polarization of the oocyte along its anterior-posterior axis. An example of this is found in Drosophila melanogaster.") -AnnotationAssertion( "GO:0048112") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "oocyte anterior/posterior axis determination") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0007314") -AnnotationAssertion(rdfs:label "oocyte anterior/posterior axis specification") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (insemination) AnnotationAssertion(Annotation( "ISBN:0582227089") "The introduction of semen or sperm into the genital tract of a female.") @@ -57936,74 +21885,6 @@ SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (single fertilization) - -AnnotationAssertion(Annotation( "GOC:ems") Annotation( "GOC:mtg_sensu") "The union of male and female gametes to form a zygote.") -AnnotationAssertion( ) -AnnotationAssertion( "biological_process") -AnnotationAssertion( "zygote biosynthesis") -AnnotationAssertion( "zygote formation") -AnnotationAssertion( "GO:0007338") -AnnotationAssertion(rdfs:label "single fertilization") -SubClassOf( ) -SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) -SubClassOf( ObjectAllValuesFrom( )) -DisjointClasses( ObjectSomeValuesFrom( )) - -# Class: (egg activation) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "PMID:9630751") "The process in which the egg becomes metabolically active, initiates protein and DNA synthesis and undergoes structural changes to its cortex and/or cytoplasm.") -AnnotationAssertion( "Wikipedia:Egg_activation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0007343") -AnnotationAssertion(rdfs:label "egg activation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (regulation of mitotic cell cycle) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:go_curators") Annotation( "GOC:tb") "Any process that modulates the rate or extent of progress through the mitotic cell cycle.") -AnnotationAssertion( "mitotic cell cycle modulation") -AnnotationAssertion( "mitotic cell cycle regulation") -AnnotationAssertion( "modulation of mitotic cell cycle progression") -AnnotationAssertion( "regulation of mitotic cell cycle progression") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "regulation of progression through mitotic cell cycle") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "mitotic cell cycle regulator") -AnnotationAssertion( "GO:0007346") -AnnotationAssertion(rdfs:label "regulation of mitotic cell cycle") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (blastoderm segmentation) - -AnnotationAssertion(Annotation( "ISBN:0879694238") Annotation( "http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm") "The hierarchical steps resulting in the progressive subdivision of the anterior/posterior axis of the embryo.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0007350") -AnnotationAssertion(rdfs:label "blastoderm segmentation") -SubClassOf( ) -SubClassOf( ) - -# Class: (tripartite regional subdivision) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:isa_complete") Annotation( "ISBN:0879694238") Annotation( "http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm") "Subdivision of the embryo along the anterior/posterior axis into anterior, posterior and terminal regions.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0007351") -AnnotationAssertion(rdfs:label "tripartite regional subdivision") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (zygotic determination of anterior/posterior axis, embryo) - -AnnotationAssertion(Annotation( "ISBN:0879694238") Annotation( "http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm") "The specification of the anterior/posterior axis of the embryo by products of genes expressed in the zygote; exemplified in insects by the gap genes, pair rule genes and segment polarity gene cascade.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0007354") -AnnotationAssertion(rdfs:label "zygotic determination of anterior/posterior axis, embryo") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - # Class: (gastrulation) AnnotationAssertion(Annotation( "GOC:curators") Annotation( "ISBN:9780878933846") "A complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals. The details of gastrulation vary from species to species, but usually result in the formation of the three primary germ layers, ectoderm, mesoderm and endoderm.") @@ -58018,36 +21899,12 @@ SubClassOf( ObjectSomeValuesFrom( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (amnioserosa formation) - -AnnotationAssertion(Annotation( "ISBN:0879694238") "Formation of the amnioserosa, an epithelium that occupies a hole in the embryonic dorsal epidermis. This occurs by the transformation of a narrow strip of cells at the dorsal midline of the blastoderm from columnar to squamous cells, accompanied by a lateral shift.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0007378") -AnnotationAssertion(rdfs:label "amnioserosa formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (pattern specification process) - -AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "GOC:isa_complete") Annotation( "ISBN:0521436125") "Any developmental process that results in the creation of defined areas or spaces within an organism to which cells respond and eventually are instructed to differentiate.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "pattern biosynthesis") -AnnotationAssertion( "pattern formation") -AnnotationAssertion( "GO:0007389") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "pattern specification process") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (ectoderm development) AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "The process whose specific outcome is the progression of the ectoderm over time, from its formation to the mature structure. In animal embryos, the ectoderm is the outer germ layer of the embryo, formed during gastrulation.") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0007398") AnnotationAssertion(rdfs:label "ectoderm development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) # Class: (nervous system development) @@ -58058,351 +21915,16 @@ AnnotationAssertion( "GO:0007399") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "nervous system development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (neuroblast proliferation) - -AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:mtg_sensu") Annotation( "GOC:sart") "The expansion of a neuroblast population by cell division. A neuroblast is any cell that will divide and give rise to a neuron.") -AnnotationAssertion( "GO:0043349") -AnnotationAssertion( "GO:0043350") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0007405") -AnnotationAssertion(rdfs:label "neuroblast proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - -# Class: (negative regulation of neuroblast proliferation) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of the proliferation of neuroblasts.") -AnnotationAssertion( "down regulation of neuroblast proliferation") -AnnotationAssertion( "down-regulation of neuroblast proliferation") -AnnotationAssertion( "downregulation of neuroblast proliferation") -AnnotationAssertion( "suppression of neuroblast proliferation") -AnnotationAssertion( "inhibition of neuroblast proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0007406") -AnnotationAssertion(rdfs:label "negative regulation of neuroblast proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (neuroblast activation) - -AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "GOC:mtg_sensu") "A change in the morphology or behavior of a neuroblast resulting from exposure to an activating factor such as a cellular or soluble ligand.") -AnnotationAssertion( "GO:0043351") -AnnotationAssertion( "GO:0043352") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0007407") -AnnotationAssertion(rdfs:label "neuroblast activation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - -# Class: (axonogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GOC:pg") Annotation( "GOC:pr") Annotation( "ISBN:0198506732") "De novo generation of a long process of a neuron, including the terminal branched region. Refers to the morphogenesis or creation of shape or form of the developing axon, which carries efferent (outgoing) action potentials from the cell body towards target cells.") -AnnotationAssertion( "GO:0007410") -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "PMID:23517308") "axon morphogenesis") -AnnotationAssertion(Annotation( ) "neuron long process generation") -AnnotationAssertion( "axon growth") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0007409") -AnnotationAssertion(rdfs:comment "Note that 'axonogenesis' differs from 'axon development' in that the latter also covers other processes, such as axon regeneration (regrowth after loss or damage, not necessarily of the whole axon).") -AnnotationAssertion(rdfs:label "axonogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (synapse assembly) - -AnnotationAssertion(Annotation( "GOC:mah") "The aggregation, arrangement and bonding together of a set of components to form a synapse. This process ends when the synapse is mature (functional).") -AnnotationAssertion( "Wikipedia:Synaptogenesis") -AnnotationAssertion(Annotation( "GOC:mah") "synapse biogenesis") -AnnotationAssertion(Annotation( "GOC:mah") "synaptogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0007416") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "synapse assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (central nervous system development) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:jid") Annotation( "ISBN:0582227089") "The process whose specific outcome is the progression of the central nervous system over time, from its formation to the mature structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.") -AnnotationAssertion( "Wikipedia:Neural_development") -AnnotationAssertion( "CNS development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0007417") -AnnotationAssertion(rdfs:label "central nervous system development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (ventral midline development) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:go_curators") Annotation( "PMID:12075342") "The process whose specific outcome is the progression of the ventral midline over time, from its formation to the mature structure. In protostomes (such as insects, snails and worms) as well as deuterostomes (vertebrates), the midline is an embryonic region that functions in patterning of the adjacent nervous tissue. The ventral midline in insects is a cell population extending along the ventral surface of the embryo and is the region from which cells detach to form the ventrally located nerve cords. In vertebrates, the midline is originally located dorsally. During development, it folds inwards and becomes the ventral part of the dorsally located neural tube and is then called the ventral midline, or floor plate.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0007418") -AnnotationAssertion(rdfs:label "ventral midline development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (ventral cord development) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:go_curators") Annotation( "http://users.rcn.com/jkimball.ma.ultranet/BiologyPages/S/Spemann.html") "The process whose specific outcome is the progression of the ventral cord over time, from its formation to the mature structure. The ventral cord is one of the distinguishing traits of the central nervous system of all arthropods (such as insects, crustaceans and arachnids) as well as many other invertebrates, such as the annelid worms.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0007419") -AnnotationAssertion(rdfs:label "ventral cord development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (brain development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GOC:tb") Annotation( "UBERON:0000955") "The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0007420") -AnnotationAssertion(rdfs:label "brain development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (peripheral nervous system development) - -AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "UBERON:0000010") "The process whose specific outcome is the progression of the peripheral nervous system over time, from its formation to the mature structure. The peripheral nervous system is one of the two major divisions of the nervous system. Nerves in the PNS connect the central nervous system (CNS) with sensory organs, other organs, muscles, blood vessels and glands.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0007422") -AnnotationAssertion(rdfs:label "peripheral nervous system development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (sensory organ development) - -AnnotationAssertion(Annotation( "GOC:go_curators") "The process whose specific outcome is the progression of sensory organs over time, from its formation to the mature structure.") -AnnotationAssertion(Annotation( "GOC:dph") "sense organ development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0007423") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "sensory organ development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (open tracheal system development) - -AnnotationAssertion(Annotation( "GOC:mtg_sensu") Annotation( "PMID:8625828") "The process whose specific outcome is the progression of an open tracheal system over time, from its formation to the mature structure. An open tracheal system is a respiratory system, a branched network of epithelial tubes that supplies oxygen to target tissues via spiracles. An example of this is found in Drosophila melanogaster.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0007424") -AnnotationAssertion(rdfs:comment "See also the fly_anatomy.ontology term 'tracheal system ; FBbt:00005024'.") -AnnotationAssertion(rdfs:label "open tracheal system development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - -# Class: (salivary gland development) - -AnnotationAssertion(Annotation( "GOC:jid") Annotation( "UBERON:0001044") "The process whose specific outcome is the progression of the salivary gland over time, from its formation to the mature structure. Salivary glands include any of the saliva-secreting exocrine glands of the oral cavity.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0007431") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "salivary gland development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (salivary gland morphogenesis) - -AnnotationAssertion(Annotation( "GOC:jid") "The process in which the anatomical structures of the salivary gland are generated and organized.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0007435") -AnnotationAssertion(rdfs:label "salivary gland morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (ectodermal digestive tract development) - -AnnotationAssertion(Annotation( "GOC:curators") "The process whose specific outcome is the progression of the ectodermal digestive tract over time, from its formation to the mature structure. The ectodermal digestive tract includes those portions that are derived from ectoderm.") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") "ectodermal gut development") -AnnotationAssertion( "GO:0007439") -AnnotationAssertion(rdfs:label "ectodermal digestive tract development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (foregut morphogenesis) - -AnnotationAssertion(Annotation( "GOC:jid") "The process in which the anatomical structures of the foregut are generated and organized.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0007440") -AnnotationAssertion(rdfs:label "foregut morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (hindgut morphogenesis) - -AnnotationAssertion(Annotation( "GOC:jid") "The process in which the anatomical structures of the hindgut are generated and organized.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0007442") -AnnotationAssertion(rdfs:label "hindgut morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (Malpighian tubule morphogenesis) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "ISBN:0582227089") "The process in which the anatomical structures of the Malpighian tubule are generated and organized. This process takes place entirely during the embryonic phase. A Malpighian tubule is a fine, thin-walled excretory tubule in insects which leads into the posterior part of the gut.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0007443") -AnnotationAssertion(rdfs:comment "See also the fly_anatomy.ontology term 'Malpighian tubule ; FBbt:00005786'.") -AnnotationAssertion(rdfs:label "Malpighian tubule morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (imaginal disc development) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "ISBN:0879694238") "The process whose specific outcome is the progression of the imaginal disc over time, from its formation to the metamorphosis to form adult structures. Imaginal discs are epithelial infoldings in the larvae of holometabolous insects that develop into adult structures (legs, antennae, wings, etc.).") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0007444") -AnnotationAssertion(rdfs:label "imaginal disc development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - -# Class: (imaginal disc growth) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:jid") Annotation( "PMID:10679387") "The increase in mass of imaginal discs by cell proliferation prior to metamorphosis. Imaginal discs are epithelial infoldings in the larvae of holometabolous insects that develop into adult structures (legs, antennae, wings, etc.) during metamorphosis from larval to adult form.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0007446") -AnnotationAssertion(rdfs:label "imaginal disc growth") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (eye-antennal disc morphogenesis) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "ISBN:0879694238") "The process in which the anatomical structures derived from the eye-antennal disc are generated and organized. This includes the transformation of an eye-antennal imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into recognizable adult structures including the eye, antenna, head capsule and maxillary palps.") -AnnotationAssertion( "eye-antennal disc metamorphosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0007455") -AnnotationAssertion(rdfs:label "eye-antennal disc morphogenesis") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (antennal development) - -AnnotationAssertion(Annotation( "http://fly.ebi.ac.uk/.bin/cvreport2?id=FBcv0004526") "The process whose specific outcome is the progression of the antenna over time, from its formation to the mature structure. The antenna are the sensory structures on the head that are capable of detecting various environmental stimuli.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0007469") -AnnotationAssertion(rdfs:label "antennal development") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (wing disc morphogenesis) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "ISBN:0879694238") "The process in which the anatomical structures derived from the wing disc are generated and organized. This includes the transformation of a wing imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into recognizable adult structures including the wing hinge, wing blade and pleura.") -AnnotationAssertion( "wing disc metamorphosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0007472") -AnnotationAssertion(rdfs:label "wing disc morphogenesis") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (imaginal disc-derived wing morphogenesis) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:mtg_sensu") "The process in which the anatomical structures of the imaginal disc-derived wing are generated and organized. The wing is an appendage modified for flying.") -AnnotationAssertion( "wing morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0007476") -AnnotationAssertion(rdfs:label "imaginal disc-derived wing morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (leg disc morphogenesis) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "ISBN:0879694238") "The process in which the anatomical structures derived from the leg disc are generated and organized. This includes the transformation of a leg imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into recognizable adult structures including the leg, coxa and ventral thoracic pleura.") -AnnotationAssertion( "leg disc metamorphosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0007478") -AnnotationAssertion(rdfs:label "leg disc morphogenesis") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (imaginal disc-derived leg morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_sensu") Annotation( "ISBN:0879694238") "The process in which the anatomical structures of a leg derived from an imaginal disc are generated and organized. A leg is a limb on which an animal walks and stands. An example of this is found in Drosophila melanogaster.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0007480") -AnnotationAssertion(rdfs:label "imaginal disc-derived leg morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - -# Class: (haltere disc morphogenesis) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "ISBN:0879694238") "The process in which the anatomical structures derived from the haltere disc are generated and organized. This includes the transformation of a haltere imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into the recognizable adult capitellum, pedicel, haltere sclerite, metathoracic spiracle and metanotum.") -AnnotationAssertion( "haltere disc metamorphosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0007481") -AnnotationAssertion(rdfs:label "haltere disc morphogenesis") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (haltere development) - -AnnotationAssertion(Annotation( "GOC:jid") Annotation( "http://www.earthlife.net") "The process whose specific outcome is the progression of the haltere over time, from its formation to the mature structure. The haltere is the club-shaped 'balancers' found on each side of the metathorax among the true flies (Diptera). They are the much-modified hind wings.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0007482") -AnnotationAssertion(rdfs:label "haltere development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (endoderm development) AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "The process whose specific outcome is the progression of the endoderm over time, from its formation to the mature structure. The endoderm is the innermost germ layer that develops into the gastrointestinal tract, the lungs and associated tissues.") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0007492") AnnotationAssertion(rdfs:label "endoderm development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (midgut development) - -AnnotationAssertion(Annotation( "GOC:jid") Annotation( "UBERON:0001045") "The process whose specific outcome is the progression of the midgut over time, from its formation to the mature structure. The midgut is the middle part of the alimentary canal from the stomach, or entrance of the bile duct, to, or including, the large intestine.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0007494") -AnnotationAssertion(rdfs:label "midgut development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - # Class: (mesoderm development) AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "The process whose specific outcome is the progression of the mesoderm over time, from its formation to the mature structure. The mesoderm is the middle germ layer that develops into muscle, bone, cartilage, blood and connective tissue.") @@ -58410,101 +21932,8 @@ AnnotationAssertion( "GO:0007498") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "mesoderm development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (fat body development) - -AnnotationAssertion(Annotation( "ISBN:0582227089") "The process whose specific outcome is the progression of the fat body over time, from its formation to the mature structure. A fat body is an insect gland dorsal to the insect gut, with a function analogous to that of the vertebrate liver. It is a storage organ for fats, glycogen and protein and is a major site of intermediary metabolism.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0007503") -AnnotationAssertion(rdfs:label "fat body development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - -# Class: (gonadal mesoderm development) - -AnnotationAssertion(Annotation( "GOC:ai") "The process whose specific outcome is the progression of the gonadal mesoderm over time, from its formation to the mature structure. The gonadal mesoderm is the middle layer of the three primary germ layers of the embryo which will go on to form the gonads of the organism.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0007506") -AnnotationAssertion(rdfs:label "gonadal mesoderm development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (heart development) - -AnnotationAssertion(Annotation( "GOC:jid") Annotation( "UBERON:0000948") "The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.") -AnnotationAssertion( "GO:0007511") -AnnotationAssertion( "Wikipedia:Heart_development") -AnnotationAssertion( "dorsal vessel development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "cardiac development") -AnnotationAssertion( "GO:0007507") -AnnotationAssertion(rdfs:label "heart development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (hemocyte development) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:mtg_sensu") "The process whose specific outcome is the progression of the hemocyte over time, from its formation to the mature structure. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen.") -AnnotationAssertion( "arthropod blood cell development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0007516") -AnnotationAssertion(rdfs:label "hemocyte development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - -# Class: (muscle organ development) - -AnnotationAssertion(Annotation( "GOC:jid") Annotation( "ISBN:0198506732") "The process whose specific outcome is the progression of the muscle over time, from its formation to the mature structure. The muscle is an organ consisting of a tissue made up of various elongated cells that are specialized to contract and thus to produce movement and mechanical work.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0007517") -AnnotationAssertion(rdfs:label "muscle organ development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (skeletal muscle tissue development) - -AnnotationAssertion(Annotation( "GOC:mtg_muscle") "The developmental sequence of events leading to the formation of adult skeletal muscle tissue. The main events are: the fusion of myoblasts to form myotubes that increase in size by further fusion to them of myoblasts, the formation of myofibrils within their cytoplasm and the establishment of functional neuromuscular junctions with motor neurons. At this stage they can be regarded as mature muscle fibers.") -AnnotationAssertion( "GO:0048637") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "myogenesis") -AnnotationAssertion( "GO:0007519") -AnnotationAssertion(rdfs:label "skeletal muscle tissue development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (somatic muscle development) - -AnnotationAssertion(Annotation( "GOC:jid") Annotation( "GOC:mtg_muscle") "The process whose specific outcome is the progression of the somatic muscle over time, from its formation to the mature structure. Somatic muscles are striated muscle structures that connect to the exoskeleton or cuticle.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0007525") -AnnotationAssertion(rdfs:label "somatic muscle development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (neuromuscular junction development) - -AnnotationAssertion(Annotation( "GOC:mtg_OBO2OWL_2013") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a neuromuscular junction.") -AnnotationAssertion( "neuromuscular junction organization") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:pr") "NMJ stability") -AnnotationAssertion(Annotation( "GOC:pr") "neuromuscular junction stability") -AnnotationAssertion( "GO:0007528") -AnnotationAssertion(rdfs:label "neuromuscular junction development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (sex differentiation) AnnotationAssertion(Annotation( "GOC:ai") "The establishment of the sex of an organism by physical differentiation.") @@ -58514,65 +21943,6 @@ AnnotationAssertion( "sex differentiation") SubClassOf( ) -# Class: (metamorphosis) - -AnnotationAssertion(Annotation( "GOC:sensu") Annotation( "ISBN:0198506732") Annotation( "ISBN:0721662544") "A biological process in which an animal physically develops after birth or hatching, involving a conspicuous and relatively abrupt change in the animal's form or structure. Examples include the change from tadpole to frog, and the change from larva to adult. An example of this is found in Drosophila melanogaster.") -AnnotationAssertion( "GO:0046698") -AnnotationAssertion( "GO:0046699") -AnnotationAssertion( "Wikipedia:Metamorphosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0007552") -AnnotationAssertion(rdfs:label "metamorphosis") -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of juvenile hormone metabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving juvenile hormone.") -AnnotationAssertion( "regulation of juvenile hormone metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0007556") -AnnotationAssertion(rdfs:label "regulation of juvenile hormone metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (regulation of juvenile hormone biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of juvenile hormone.") -AnnotationAssertion( "regulation of juvenile hormone anabolism") -AnnotationAssertion( "regulation of juvenile hormone biosynthesis") -AnnotationAssertion( "regulation of juvenile hormone formation") -AnnotationAssertion( "regulation of juvenile hormone synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0007557") -AnnotationAssertion(rdfs:label "regulation of juvenile hormone biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of juvenile hormone secretion) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of juvenile hormone secretion.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0007558") -AnnotationAssertion(rdfs:label "regulation of juvenile hormone secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (imaginal disc morphogenesis) - -AnnotationAssertion(Annotation( "GOC:jid") "The process in which the anatomical structures derived from an imaginal disc are generated and organized. The imaginal discs are epithelial infoldings in the larvae of holometabolous insects that develop into adult appendages (legs, antennae, wings, etc.) during metamorphosis from larval to adult form.") -AnnotationAssertion( "GO:0007452") -AnnotationAssertion( "imaginal disc metamorphosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0007560") -AnnotationAssertion(rdfs:label "imaginal disc morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (eclosion) AnnotationAssertion(Annotation( "GOC:dgh") Annotation( "GOC:dos") Annotation( "GOC:mah") Annotation( "ISBN:0198600461") "The emergence of an adult insect from a pupa case.") @@ -58583,15 +21953,6 @@ AnnotationAssertion(rdfs:label "eclo SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (regulation of eclosion) - -AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198600461") "Any process that modulates the frequency, rate or extent of the emergence of an insect from a pupa-case or of a larva from an egg.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0007563") -AnnotationAssertion(rdfs:label "regulation of eclosion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - # Class: (female pregnancy) AnnotationAssertion(Annotation( "ISBN:0192800825") "The set of physiological processes that allow an embryo or foetus to develop within the body of a female animal. It covers the time from fertilization of a female ovum by a male spermatozoon until birth.") @@ -58607,17 +21968,6 @@ SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectAllValuesFrom( )) -# Class: (embryo implantation) - -AnnotationAssertion(Annotation( "GOC:isa_complete") Annotation( "http://www.medterms.com") "Attachment of the blastocyst to the uterine lining.") -AnnotationAssertion( "blastocyst implantation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0007566") -AnnotationAssertion(rdfs:label "embryo implantation") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (respiratory gaseous exchange by respiratory system) AnnotationAssertion(Annotation( "ISBN:0198506732") "The process of gaseous exchange between an organism and its environment. In plants, microorganisms, and many small animals, air or water makes direct contact with the organism's cells or tissue fluids, and the processes of diffusion supply the organism with dioxygen (O2) and remove carbon dioxide (CO2). In larger animals the efficiency of gaseous exchange is improved by specialized respiratory organs, such as lungs and gills, which are ventilated by breathing mechanisms.") @@ -58694,7 +22044,6 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0007596") AnnotationAssertion(rdfs:label "blood coagulation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) @@ -58836,32 +22185,6 @@ AnnotationAssertion( "copulation") SubClassOf( ) -# Class: (rhythmic behavior) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "GOC:pr") "The specific behavior of an organism that recur with measured regularity.") -AnnotationAssertion( "rhythmic behavioral response to stimulus") -AnnotationAssertion( "rhythmic behaviour") -AnnotationAssertion( "rhythmic behavioural response to stimulus") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0007622") -AnnotationAssertion(rdfs:label "rhythmic behavior") -SubClassOf( ) - -# Class: (circadian rhythm) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:go_curators") "Any biological process in an organism that recurs with a regularity of approximately 24 hours.") -AnnotationAssertion( "GO:0050895") -AnnotationAssertion( "Wikipedia:Circadian_rhythm") -AnnotationAssertion( "circadian process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "circadian response") -AnnotationAssertion( "response to circadian rhythm") -AnnotationAssertion( "GO:0007623") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "circadian rhythm") -SubClassOf( ) - # Class: (grooming behavior) AnnotationAssertion(Annotation( "GOC:jl") Annotation( "GOC:pr") "The specific behavior of an organism relating to grooming, cleaning and brushing to remove dirt and parasites.") @@ -58951,128 +22274,8 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0008016") AnnotationAssertion(rdfs:label "regulation of heart contraction") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (microtubule binding) - -AnnotationAssertion(Annotation( "GOC:krc") "Binding to a microtubule, a filament composed of tubulin monomers.") -AnnotationAssertion(Annotation(rdfs:label "Viral UL47:UL48 Proteins Bind HCMV Tegumented Virion to Host Microtuble and Dynein complexs") "Reactome:R-HSA-9614343") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "microtubule severing activity") -AnnotationAssertion( "microtubule/chromatin interaction") -AnnotationAssertion( "GO:0008017") -AnnotationAssertion(rdfs:label "microtubule binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (monocarboxylic acid transmembrane transporter activity) - -AnnotationAssertion(Annotation( "GOC:ai") "Enables the transfer of monocarboxylic acids from one side of a membrane to the other. A monocarboxylic acid is an organic acid with one COOH group.") -AnnotationAssertion( "GO:0008505") -AnnotationAssertion(Annotation(rdfs:label "SLC5A8 transports monocarboxylates from extracellular region to cytosol") "Reactome:R-HSA-429749") -AnnotationAssertion(Annotation(rdfs:label "SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol") "Reactome:R-HSA-433698") -AnnotationAssertion(Annotation(rdfs:label "Defective SLC16A1 does not cotransport monocarboxylates, H+ from extracellular region to cytosol") "Reactome:R-HSA-5624211") -AnnotationAssertion(Annotation(rdfs:label "SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol") "Reactome:R-HSA-9645220") -AnnotationAssertion( "monocarboxylate carrier") -AnnotationAssertion( "prostaglandin/thromboxane transporter activity") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0008028") -AnnotationAssertion(rdfs:label "monocarboxylic acid transmembrane transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (ocellus development) - -AnnotationAssertion(Annotation( "http://fly.ebi.ac.uk/.bin/cvreport2?id=FBcv0004540") "The process whose specific outcome is the progression of the ocellus over time, from its formation to the mature structure. The ocellus is a simple visual organ of insects.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0008056") -AnnotationAssertion(rdfs:label "ocellus development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (chitin binding) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0198506732") "Binding to chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0008061") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "chitin binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (glutamate receptor activity) - -AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:signaling") "Combining with glutamate and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0008066") -AnnotationAssertion(rdfs:label "glutamate receptor activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (mesodermal cell migration) - -AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:mah") Annotation( "GOC:sat") Annotation( "GOC:tb") Annotation( "PMID:25119047") "The orderly movement of mesodermal cells from one site to another.") -AnnotationAssertion( "mesoderm cell migration") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0008078") -AnnotationAssertion(rdfs:label "mesodermal cell migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (axo-dendritic transport) - -AnnotationAssertion(Annotation( "ISBN:0815316194") "The directed movement of organelles or molecules along microtubules in neuron projections.") -AnnotationAssertion( "Wikipedia:Axoplasmic_transport") -AnnotationAssertion( "axon cargo transport") -AnnotationAssertion( "axonal transport") -AnnotationAssertion( "axoplasmic transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0008088") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "axo-dendritic transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (anterograde axonal transport) - -AnnotationAssertion(Annotation( "ISBN:0815316194") "The directed movement of organelles or molecules along microtubules from the cell body toward the cell periphery in nerve cell axons.") -AnnotationAssertion( "anterograde axon cargo transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0008089") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "anterograde axonal transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (retrograde axonal transport) - -AnnotationAssertion(Annotation( "ISBN:0815316194") "The directed movement of organelles or molecules along microtubules from the cell periphery toward the cell body in nerve cell axons.") -AnnotationAssertion( "retrograde axon cargo transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0008090") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "retrograde axonal transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (cytoskeletal protein binding) - -AnnotationAssertion(Annotation( "GOC:mah") "Binding to a protein component of a cytoskeleton (actin, microtubule, or intermediate filament cytoskeleton).") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0008092") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "cytoskeletal protein binding") -SubClassOf( ) - # Class: (protein localization) AnnotationAssertion(Annotation( "GOC:ai") "Any process in which a protein is transported to, or maintained in, a specific location.") @@ -59092,28 +22295,9 @@ AnnotationAssertion( "GO:0008104") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "protein localization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) -# Class: (transcription factor binding) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "Binding to a transcription factor, a protein required to initiate or regulate transcription.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/19354"^^xsd:anyURI) -AnnotationAssertion( "TF binding") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "transcription regulator binding") -AnnotationAssertion( "GO:0008134") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "Note that this term should not be used for direct annotation. Please consier one of the more specific descendants, GO:0140297 ; DNA-binding transcription factor binding, GO:0140296 ; general transcription initiation factor binding or GO:0001221 ; transcription coregulator binding.") -AnnotationAssertion(rdfs:label "transcription factor binding") -SubClassOf( ) - # Class: (biological_process) AnnotationAssertion(Annotation( "GOC:pdt") "A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence.") @@ -59167,21 +22351,6 @@ SubClassOf( ) DisjointClasses( ) -# Class: (neuropeptide receptor activity) - -AnnotationAssertion(Annotation( "GOC:ai") "Combining with a neuropeptide to initiate a change in cell activity.") -AnnotationAssertion( ) -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0008188") -AnnotationAssertion(rdfs:label "neuropeptide receptor activity") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) -DisjointClasses( ObjectSomeValuesFrom( )) - # Class: (steroid metabolic process) AnnotationAssertion(Annotation( "ISBN:0198547684") "The chemical reactions and pathways involving steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.") @@ -59190,7 +22359,6 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0008202") AnnotationAssertion(rdfs:label "steroid metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) @@ -59201,7 +22369,6 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0008206") AnnotationAssertion(rdfs:label "bile acid metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ) @@ -59213,35 +22380,10 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0008207") AnnotationAssertion(rdfs:label "C21-steroid hormone metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ) -# Class: (C21-steroid hormone catabolic process) - -AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways resulting in the breakdown of C21-steroid hormones, steroid compounds containing 21 carbons which function as hormones.") -AnnotationAssertion( "C21-steroid hormone breakdown") -AnnotationAssertion( "C21-steroid hormone catabolism") -AnnotationAssertion( "C21-steroid hormone degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0008208") -AnnotationAssertion(rdfs:label "C21-steroid hormone catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (glucocorticoid metabolic process) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving glucocorticoids, hormonal C21 corticosteroids synthesized from cholesterol. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects.") -AnnotationAssertion( "glucocorticoid metabolism") -AnnotationAssertion( "glucocorticosteroid metabolic process") -AnnotationAssertion( "glucocorticosteroid metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0008211") -AnnotationAssertion(rdfs:label "glucocorticoid metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - # Class: (mineralocorticoid metabolic process) AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving mineralocorticoids, hormonal C21 corticosteroids synthesized from cholesterol. Mineralocorticoids act primarily on water and electrolyte balance.") @@ -59249,7 +22391,6 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0008212") AnnotationAssertion(rdfs:label "mineralocorticoid metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ) @@ -59267,55 +22408,6 @@ AnnotationAssertion(rdfs:label "regu SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (cell death) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:mtg_apoptosis") Annotation( "PMID:25236395") "Any biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as apoptotic bodies). The cell corpse (or its fragments) may be engulfed by an adjacent cell in vivo, but engulfment of whole cells should not be considered a strict criteria to define cell death as, under some circumstances, live engulfed cells can be released from phagosomes (see PMID:18045538).") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/24680"^^xsd:anyURI) -AnnotationAssertion( "biological_process") -AnnotationAssertion( "accidental cell death") -AnnotationAssertion( "necrosis") -AnnotationAssertion( "GO:0008219") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "This term should not be used for direct annotation, it is currently kept in GO as a placeholder for describing cell death phenotypes in uPHENO. When information is provided on a programmed cell death mechanism, annotations should be made to the appropriate descendant of 'cell death' (such as, but not limited to, GO:0097300 'programmed necrotic cell death' or GO:0006915 'apoptotic process'). Unintentional cell death, i.e. cell death caused by injury, ageing, or cell phenotypes observed as a result of a pathological mutation in an essential gene should NOT be annotated using GO terms.") -AnnotationAssertion(rdfs:label "cell death") -SubClassOf( ) - -# Class: (G protein-coupled amine receptor activity) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:dph") "Combining with an extracellular amine and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.") -AnnotationAssertion( "G-protein coupled amine receptor activity") -AnnotationAssertion(Annotation( "GOC:bf") "amine receptor activity, G-protein coupled") -AnnotationAssertion( "biogenic amine receptor") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0008227") -AnnotationAssertion(rdfs:label "G protein-coupled amine receptor activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (sulfate transport) - -AnnotationAssertion(Annotation( "GOC:krc") "The directed movement of sulfate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion( "GO:0006870") -AnnotationAssertion( "sulphate transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0008272") -AnnotationAssertion(rdfs:label "sulfate transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of G protein-coupled receptor signaling pathway) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of G protein-coupled receptor signaling pathway.") -AnnotationAssertion( "regulation of G protein coupled receptor protein signaling pathway") -AnnotationAssertion( "regulation of G protein coupled receptor protein signalling pathway") -AnnotationAssertion( "regulation of G-protein coupled receptor protein signaling pathway") -AnnotationAssertion( "regulation of G-protein coupled receptor protein signalling pathway") -AnnotationAssertion( "regulation of G-protein-coupled receptor protein signalling pathway") -AnnotationAssertion( "regulation of GPCR protein signaling pathway") -AnnotationAssertion( "regulation of GPCR protein signalling pathway") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0008277") -AnnotationAssertion(rdfs:label "regulation of G protein-coupled receptor signaling pathway") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (cell population proliferation) AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:mb") "The multiplication or reproduction of cells, resulting in the expansion of a cell population.") @@ -59336,141 +22428,6 @@ SubClassOf( ObjectComplementOf(Object SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) DisjointClasses( ObjectSomeValuesFrom( )) -# Class: (positive regulation of cell population proliferation) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the rate or extent of cell proliferation.") -AnnotationAssertion( ) -AnnotationAssertion( "up regulation of cell proliferation") -AnnotationAssertion( "up-regulation of cell proliferation") -AnnotationAssertion( "upregulation of cell proliferation") -AnnotationAssertion( "activation of cell proliferation") -AnnotationAssertion( "stimulation of cell proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "positive regulation of cell proliferation") -AnnotationAssertion( "GO:0008284") -AnnotationAssertion(rdfs:label "positive regulation of cell population proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) -DisjointClasses( ObjectSomeValuesFrom( )) - -# Class: (negative regulation of cell population proliferation) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents or reduces the rate or extent of cell proliferation.") -AnnotationAssertion( ) -AnnotationAssertion( "down regulation of cell proliferation") -AnnotationAssertion( "down-regulation of cell proliferation") -AnnotationAssertion( "downregulation of cell proliferation") -AnnotationAssertion( "inhibition of cell proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "negative regulation of cell proliferation") -AnnotationAssertion( "GO:0008285") -AnnotationAssertion(rdfs:label "negative regulation of cell population proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) -DisjointClasses( ObjectSomeValuesFrom( )) - -# Class: (insulin receptor signaling pathway) - -AnnotationAssertion(Annotation( "GOC:ceb") "The series of molecular signals generated as a consequence of the insulin receptor binding to insulin.") -AnnotationAssertion( "insulin receptor signalling pathway") -AnnotationAssertion( "daf-2 receptor signaling pathway") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0008286") -AnnotationAssertion(rdfs:label "insulin receptor signaling pathway") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - -# Class: (lipid binding) - -AnnotationAssertion(Annotation( "GOC:ai") "Binding to a lipid.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0008289") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "lipid binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (acetylcholine metabolic process) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "GOC:nln") Annotation( "ISBN:0192800752") "The chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues.") -AnnotationAssertion( "acetylcholine metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0008291") -AnnotationAssertion(rdfs:label "acetylcholine metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (acetylcholine biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0192800752") "The chemical reactions and pathways resulting in the formation of acetylcholine, the acetic acid ester of the organic base choline.") -AnnotationAssertion( "acetylcholine anabolism") -AnnotationAssertion( "acetylcholine biosynthesis") -AnnotationAssertion( "acetylcholine formation") -AnnotationAssertion( "acetylcholine synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0008292") -AnnotationAssertion(rdfs:label "acetylcholine biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (isoprenoid biosynthetic process) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of an isoprenoid compound, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues.") -AnnotationAssertion( "GO:0009241") -AnnotationAssertion( "MetaCyc:POLYISOPRENSYN-PWY") -AnnotationAssertion( "isoprenoid anabolism") -AnnotationAssertion( "isoprenoid biosynthesis") -AnnotationAssertion( "isoprenoid formation") -AnnotationAssertion( "isoprenoid synthesis") -AnnotationAssertion( "polyisoprenoid anabolism") -AnnotationAssertion( "polyisoprenoid biosynthesis") -AnnotationAssertion( "polyisoprenoid biosynthetic process") -AnnotationAssertion( "polyisoprenoid formation") -AnnotationAssertion( "polyisoprenoid synthesis") -AnnotationAssertion( "polyterpene biosynthesis") -AnnotationAssertion( "polyterpene biosynthetic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0008299") -AnnotationAssertion(rdfs:label "isoprenoid biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (isoprenoid catabolic process) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of an isoprenoid compound, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues.") -AnnotationAssertion( "GO:0016097") -AnnotationAssertion( "isoprenoid breakdown") -AnnotationAssertion( "isoprenoid catabolism") -AnnotationAssertion( "isoprenoid degradation") -AnnotationAssertion( "polyisoprenoid breakdown") -AnnotationAssertion( "polyisoprenoid catabolic process") -AnnotationAssertion( "polyisoprenoid catabolism") -AnnotationAssertion( "polyisoprenoid degradation") -AnnotationAssertion( "polyterpene catabolic process") -AnnotationAssertion( "polyterpene catabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0008300") -AnnotationAssertion(rdfs:label "isoprenoid catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - # Class: (associative learning) AnnotationAssertion(Annotation( "ISBN:0582227089") "Learning by associating a stimulus (the cause) with a particular outcome (the effect).") @@ -59484,91 +22441,6 @@ AnnotationAssertion( "associative learning") SubClassOf( ) -# Class: (protein transmembrane transporter activity) - -AnnotationAssertion(Annotation( "GOC:jl") "Enables the transfer of a protein from one side of a membrane to the other.") -AnnotationAssertion( "GO:0015266") -AnnotationAssertion( "GO:0015463") -AnnotationAssertion(Annotation(rdfs:label "TOMM40 complex translocates proteins from the cytosol to the mitochondrial intermembrane space") "Reactome:R-HSA-1268022") -AnnotationAssertion(Annotation(rdfs:label "TIMM23 PAM translocates proteins from the mitochondrial intermembrane space to the mitochondrial matrix") "Reactome:R-HSA-1299475") -AnnotationAssertion(Annotation(rdfs:label "Monoubiquitinated N-myristoyl GAG polyprotein is targeted to the late endosomal vesicle membrane by the ESCRT-I complex") "Reactome:R-HSA-184269") -AnnotationAssertion(Annotation(rdfs:label "Transport of GAG to the Plasma Membrane") "Reactome:R-HSA-3149434") -AnnotationAssertion(Annotation(rdfs:label "Pink1 is recruited from the cytoplasm to the mitochondria") "Reactome:R-HSA-5205661") -AnnotationAssertion(Annotation(rdfs:label "pagA(197-794):ANTRX2 oligomer transports cya and lef (target cell endosome to cytosol)") "Reactome:R-HSA-5210943") -AnnotationAssertion(Annotation(rdfs:label "pagA(197-794):ANTRX1 oligomer transports cya and lef (target cell endosome to cytosol)") "Reactome:R-HSA-5210947") -AnnotationAssertion(Annotation(rdfs:label "tetX HC transports tetX LC from target cell endosome membrane into cytosol") "Reactome:R-HSA-5228406") -AnnotationAssertion(Annotation(rdfs:label "AP4 transports APP from trans-Golgi network to endosome lumen") "Reactome:R-HSA-5229111") -AnnotationAssertion(Annotation(rdfs:label "botB HC transports botB LC from target cell synaptic vesicle membrane into cytosol") "Reactome:R-HSA-5244404") -AnnotationAssertion(Annotation(rdfs:label "botA HC transports botA LC from target cell synaptic vesicle membrane into cytosol") "Reactome:R-HSA-5244428") -AnnotationAssertion(Annotation(rdfs:label "botE HC transports botE LC from target cell synaptic vesicle membrane into cytosol") "Reactome:R-HSA-5244506") -AnnotationAssertion(Annotation(rdfs:label "botC HC transports botC LC from target cell synaptic vesicle membrane to cytosol") "Reactome:R-HSA-5246514") -AnnotationAssertion(Annotation(rdfs:label "botD HC transports botD LC from target cell synaptic vesicle membrane into cytosol") "Reactome:R-HSA-5250616") -AnnotationAssertion(Annotation(rdfs:label "botF HC transports botF LC from target cell synaptic vesicle membrane into cytosol") "Reactome:R-HSA-5250884") -AnnotationAssertion(Annotation(rdfs:label "botG HC transports botG LC from target cell synaptic vesicle membrane into cytosol") "Reactome:R-HSA-5250972") -AnnotationAssertion(Annotation(rdfs:label "DT fragment B transports DT fragment A from target cell endosome membrane") "Reactome:R-HSA-5336420") -AnnotationAssertion(Annotation(rdfs:label "SecA2 transports SapM from cytoplasm to cytosol") "Reactome:R-HSA-9636375") -AnnotationAssertion(Annotation(rdfs:label "HCMV C Nucleocapsid Translocation") "Reactome:R-HSA-9698930") -AnnotationAssertion(Annotation(rdfs:label "HCMV B Nucleocapsid Translocation") "Reactome:R-HSA-9698933") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "protein channel activity") -AnnotationAssertion( "GO:0008320") -AnnotationAssertion(rdfs:label "protein transmembrane transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "GO_REF:0000090") ObjectSomeValuesFrom( )) - -# Class: (monoatomic cation transmembrane transporter activity) - -AnnotationAssertion(Annotation( "GOC:dgf") Annotation( "GOC:mtg_transport") Annotation( "ISBN:0815340729") "Enables the transfer of cation from one side of a membrane to the other.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/24479"^^xsd:anyURI) -AnnotationAssertion( "cation transmembrane transporter activity") -AnnotationAssertion( "transmembrane cation transporter activity") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0008324") -AnnotationAssertion(rdfs:label "monoatomic cation transmembrane transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (glial cell migration) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "GOC:mtg_sensu") "The orderly movement of a glial cell, non-neuronal cells that provide support and nutrition, maintain homeostasis, form myelin, and participate in signal transmission in the nervous system.") -AnnotationAssertion( "GO:0043359") -AnnotationAssertion( "glia cell migration") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0008347") -AnnotationAssertion(rdfs:label "glial cell migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - -# Class: (negative regulation of antimicrobial humoral response) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate, or extent of an antimicrobial humoral response.") -AnnotationAssertion( "GO:0042154") -AnnotationAssertion( "GO:0042155") -AnnotationAssertion( "attenuation of antimicrobial humoral response") -AnnotationAssertion( "down regulation of antimicrobial humoral response") -AnnotationAssertion( "down-regulation of antimicrobial humoral response") -AnnotationAssertion( "downregulation of antimicrobial humoral response") -AnnotationAssertion( "inhibition of antimicrobial humoral response") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0008348") -AnnotationAssertion(rdfs:label "negative regulation of antimicrobial humoral response") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (germ cell migration) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:jl") "The orderly movement of a cell specialized to produce haploid gametes through the embryo from its site of production to the place where the gonads will form.") -AnnotationAssertion( "germ-cell migration") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "primordial germ cell migration") -AnnotationAssertion( "GO:0008354") -AnnotationAssertion(rdfs:label "germ cell migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (olfactory learning) AnnotationAssertion(Annotation( "ISBN:0582227089") "Any process in an organism in which a relatively long-lasting adaptive behavioral change occurs in response to (repeated) exposure to an olfactory cue.") @@ -59578,39 +22450,6 @@ AnnotationAssertion(rdfs:label "olfa SubClassOf( ) SubClassOf( ) -# Class: (asymmetric cell division) - -AnnotationAssertion(Annotation( "PMID:11672519") "The asymmetric division of cells to produce two daughter cells with different developmental potentials. It is of fundamental significance for the generation of cell diversity.") -AnnotationAssertion( "Wikipedia:Asymmetric_cell_division") -AnnotationAssertion( "asymmetrical cell division") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "asymmetric cytokinesis") -AnnotationAssertion( "asymmetrical cytokinesis") -AnnotationAssertion( "GO:0008356") -AnnotationAssertion(rdfs:label "asymmetric cell division") -SubClassOf( ) - -# Class: (maternal determination of anterior/posterior axis, embryo) - -AnnotationAssertion(Annotation( "ISBN:0879694238") Annotation( "http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm") "The specification of the anterior/posterior axis of the embryo by gradients of maternally-transcribed gene products; exemplified in insects by the morphogens, bicoid and nanos.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0008358") -AnnotationAssertion(rdfs:label "maternal determination of anterior/posterior axis, embryo") -SubClassOf( ) - -# Class: (axon ensheathment) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0878932437") "Any process in which the axon of a neuron is insulated, and that insulation maintained, thereby preventing dispersion of the electrical signal.") -AnnotationAssertion( "GO:0042553") -AnnotationAssertion( "cellular axon ensheathment") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "cellular nerve ensheathment") -AnnotationAssertion( "nerve ensheathment") -AnnotationAssertion( "GO:0008366") -AnnotationAssertion(rdfs:label "axon ensheathment") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (gonad development) AnnotationAssertion(Annotation( "GOC:ems") Annotation( "ISBN:0198506732") "The process whose specific outcome is the progression of the gonad over time, from its formation to the mature structure. The gonad is an animal organ that produces gametes; in some species it also produces hormones.") @@ -59618,65 +22457,12 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:0008406") AnnotationAssertion(rdfs:label "gonad development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (melatonin receptor activity) - -AnnotationAssertion(Annotation( "GOC:ai") Annotation( "ISBN:0198506732") "Combining with melatonin, N-acetyl-5-methoxytryptamine, to initiate a change in cell activity. Melatonin is a neuroendocrine substance that stimulates the aggregation of melanosomes in melanophores, thus lightening the skin.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0008502") -AnnotationAssertion(rdfs:label "melatonin receptor activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (monoamine transmembrane transporter activity) - -AnnotationAssertion(Annotation( "GOC:mah") "Enables the transfer of monoamines, organic compounds that contain one amino group that is connected to an aromatic ring by an ethylene group (-CH2-CH2-), from one side of a membrane to the other.") -AnnotationAssertion( "GO:0015201") -AnnotationAssertion(Annotation(rdfs:label "Loading of dopamine into synaptic veiscles") "Reactome:R-HSA-372542") -AnnotationAssertion(Annotation(rdfs:label "SLC6A3 cotransports DA, Na+ from extracellular region to cytosol") "Reactome:R-HSA-379393") -AnnotationAssertion(Annotation(rdfs:label "loading of Serotonin in synaptic vesicles") "Reactome:R-HSA-380586") -AnnotationAssertion(Annotation(rdfs:label "Reuptake of serotonin from the synapse") "Reactome:R-HSA-380620") -AnnotationAssertion(Annotation(rdfs:label "VMAT1/2 can mediate the transport of biogenic amines") "Reactome:R-HSA-444160") -AnnotationAssertion(Annotation(rdfs:label "Defective SLC6A3 does not cotransport DA, Na+ from extracellular region to cytosol") "Reactome:R-HSA-5660706") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0008504") -AnnotationAssertion(rdfs:label "monoamine transmembrane transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (organic anion transmembrane transporter activity) - -AnnotationAssertion(Annotation( "GOC:ai") "Enables the transfer of organic anions from one side of a membrane to the other. Organic anions are atoms or small molecules with a negative charge which contain carbon in covalent linkage.") -AnnotationAssertion(Annotation(rdfs:label "Growing HA is extruded from the cell by ABCC5") "Reactome:R-HSA-2142859") -AnnotationAssertion(Annotation(rdfs:label "OAT1-3 transport organic anions with antiport of dicarboxylic acids") "Reactome:R-HSA-561041") -AnnotationAssertion(Annotation(rdfs:label "SLC22A8 transports Cipro into renal cell") "Reactome:R-HSA-9794830") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0008514") -AnnotationAssertion(rdfs:label "organic anion transmembrane transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (G protein-coupled peptide receptor activity) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Combining with a peptide and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.") -AnnotationAssertion( "G protein coupled peptide receptor activity") -AnnotationAssertion( "G-protein coupled peptide receptor activity") -AnnotationAssertion( "peptide receptor activity, G protein coupled") -AnnotationAssertion(Annotation( "GOC:bf") "peptide receptor activity, G-protein coupled") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0008528") -AnnotationAssertion(rdfs:label "G protein-coupled peptide receptor activity") -SubClassOf( ) -SubClassOf( ) - # Class: (epidermis development) AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "UBERON:0001003") "The process whose specific outcome is the progression of the epidermis over time, from its formation to the mature structure. The epidermis is the outer epithelial layer of an animal, it may be a single layer that produces an extracellular material (e.g. the cuticle of arthropods) or a complex stratified squamous epithelium, as in the case of many vertebrate species.") @@ -59690,18 +22476,6 @@ SubClassOf( ObjectComplementOf(Object SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) DisjointClasses( ObjectSomeValuesFrom( )) -# Class: (male gonad development) - -AnnotationAssertion(Annotation( "GOC:jid") "The process whose specific outcome is the progression of the male gonad over time, from its formation to the mature structure.") -AnnotationAssertion(Annotation( "GOC:sl") "testicular development") -AnnotationAssertion(Annotation( "GOC:sl") "testis development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0008584") -AnnotationAssertion(rdfs:label "male gonad development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (female gonad development) AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GOC:tb") "The process whose specific outcome is the progression of the female gonad over time, from its formation to the mature structure.") @@ -59712,47 +22486,12 @@ AnnotationAssertion(Annotation( "GOC:sl") "ovary development") AnnotationAssertion( "GO:0008585") AnnotationAssertion(rdfs:label "female gonad development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) DisjointClasses( ObjectSomeValuesFrom( )) -# Class: (imaginal disc-derived wing vein morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_sensu") "The process in which anatomical structures of the veins on an imaginal disc-derived wing are generated and organized.") -AnnotationAssertion( "wing vein morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0008586") -AnnotationAssertion(rdfs:label "imaginal disc-derived wing vein morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (photoreceptor cell morphogenesis) - -AnnotationAssertion(Annotation( "GOC:jid") Annotation( "GOC:mah") "The process in which the structures of a photoreceptor cell are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a photoreceptor cell, a sensory cell that reacts to the presence of light. An example of this is found in Drosophila melanogaster.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "photoreceptor development") -AnnotationAssertion( "GO:0008594") -AnnotationAssertion(rdfs:label "photoreceptor cell morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (anterior/posterior axis specification, embryo) - -AnnotationAssertion(Annotation( "ISBN:0879694238") Annotation( "http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm") "The specification of the anterior/posterior axis of the embryo by the products of genes expressed maternally and genes expressed in the zygote.") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") "anterior/posterior axis determination, embryo") -AnnotationAssertion( "GO:0008595") -AnnotationAssertion(rdfs:label "anterior/posterior axis specification, embryo") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (lipid biosynthetic process) AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways resulting in the formation of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.") @@ -59764,112 +22503,9 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:0008610") AnnotationAssertion(rdfs:label "lipid biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) -# Class: (carbohydrate transport) - -AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of carbohydrate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carbohydrates are a group of organic compounds based of the general formula Cx(H2O)y.") -AnnotationAssertion( "GO:0006861") -AnnotationAssertion( "GO:0008644") -AnnotationAssertion( "sugar transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0008643") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "carbohydrate transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (hexose transmembrane transport) - -AnnotationAssertion(Annotation( "GOC:vw") "The process in which hexose is transported across a membrane. Hexoses are aldoses with a chain of six carbon atoms in the molecule.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2010-04-08T10:27:23Z") -AnnotationAssertion( "GO:0008646") -AnnotationAssertion( "GO:0008647") -AnnotationAssertion( "GO:0035428") -AnnotationAssertion( "high-affinity hexose transport") -AnnotationAssertion( "low-affinity hexose transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "hexose membrane transport") -AnnotationAssertion( "hexose transport") -AnnotationAssertion( "GO:0008645") -AnnotationAssertion(rdfs:comment "Note that this term is not intended for use in annotating lateral movement within membranes.") -AnnotationAssertion(rdfs:label "hexose transmembrane transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (amino acid biosynthetic process) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of amino acids, organic acids containing one or more amino substituents.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/17904"^^xsd:anyURI) -AnnotationAssertion( "Wikipedia:Amino_acid_synthesis") -AnnotationAssertion( "amino acid anabolism") -AnnotationAssertion( "amino acid biosynthesis") -AnnotationAssertion( "amino acid formation") -AnnotationAssertion( "amino acid synthesis") -AnnotationAssertion( "cellular amino acid biosynthetic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0008652") -AnnotationAssertion(rdfs:label "amino acid biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (phospholipid biosynthetic process) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of a phospholipid, a lipid containing phosphoric acid as a mono- or diester.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/20092"^^xsd:anyURI) -AnnotationAssertion( "MetaCyc:PHOSLIPSYN-PWY") -AnnotationAssertion( "MetaCyc:PHOSLIPSYN2-PWY") -AnnotationAssertion( "phospholipid anabolism") -AnnotationAssertion( "phospholipid biosynthesis") -AnnotationAssertion( "phospholipid formation") -AnnotationAssertion( "phospholipid synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0008654") -AnnotationAssertion(rdfs:label "phospholipid biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (catabolic process) - -AnnotationAssertion(Annotation( "ISBN:0198547684") "The chemical reactions and pathways resulting in the breakdown of substances, including the breakdown of carbon compounds with the liberation of energy for use by the cell or organism.") -AnnotationAssertion( "jl") -AnnotationAssertion( "2012-10-17T15:52:35Z") -AnnotationAssertion( "GO:0044243") -AnnotationAssertion( "GO:0044712") -AnnotationAssertion( "Wikipedia:Catabolism") -AnnotationAssertion( "breakdown") -AnnotationAssertion( "catabolism") -AnnotationAssertion( "degradation") -AnnotationAssertion( "multicellular organismal catabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "single-organism catabolic process") -AnnotationAssertion( "GO:0009056") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "catabolic process") -SubClassOf( ) - -# Class: (macromolecule catabolic process) - -AnnotationAssertion(Annotation( "GOC:mah") "The chemical reactions and pathways resulting in the breakdown of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.") -AnnotationAssertion( "GO:0043285") -AnnotationAssertion( "GO:0044266") -AnnotationAssertion(Annotation( "GOC:mtg_chebi_dec09") "biopolymer catabolic process") -AnnotationAssertion( "macromolecule breakdown") -AnnotationAssertion( "macromolecule catabolism") -AnnotationAssertion( "macromolecule degradation") -AnnotationAssertion( "multicellular organismal macromolecule catabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "cellular macromolecule catabolic process") -AnnotationAssertion( "cellular macromolecule catabolism") -AnnotationAssertion( "cellular macromolecule degradation") -AnnotationAssertion( "GO:0009057") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "macromolecule catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (biosynthetic process) AnnotationAssertion(Annotation( "GOC:curators") Annotation( "ISBN:0198547684") "The chemical reactions and pathways resulting in the formation of substances; typically the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones.") @@ -59907,37 +22543,10 @@ AnnotationAssertion( "GO:0009059") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "macromolecule biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ) -# Class: (fatty acid catabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways resulting in the breakdown of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes.") -AnnotationAssertion( "Wikipedia:Fatty_acid_degradation") -AnnotationAssertion( "fatty acid breakdown") -AnnotationAssertion( "fatty acid catabolism") -AnnotationAssertion( "fatty acid degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0009062") -AnnotationAssertion(rdfs:label "fatty acid catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (amino acid catabolic process) - -AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways resulting in the breakdown of amino acids, organic acids containing one or more amino substituents.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/17904"^^xsd:anyURI) -AnnotationAssertion( "amino acid breakdown") -AnnotationAssertion( "amino acid catabolism") -AnnotationAssertion( "amino acid degradation") -AnnotationAssertion( "cellular amino acid catabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0009063") -AnnotationAssertion(rdfs:label "amino acid catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (glutamine family amino acid metabolic process) AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways involving amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline.") @@ -59945,470 +22554,8 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0009064") AnnotationAssertion(rdfs:label "glutamine family amino acid metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (glutamine family amino acid catabolic process) - -AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways resulting in the breakdown of amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline.") -AnnotationAssertion( "glutamine family amino acid breakdown") -AnnotationAssertion( "glutamine family amino acid catabolism") -AnnotationAssertion( "glutamine family amino acid degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0009065") -AnnotationAssertion(rdfs:label "glutamine family amino acid catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (glutamine family amino acid biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways resulting in the formation of amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline.") -AnnotationAssertion( "glutamine family amino acid anabolism") -AnnotationAssertion( "glutamine family amino acid biosynthesis") -AnnotationAssertion( "glutamine family amino acid formation") -AnnotationAssertion( "glutamine family amino acid synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0009084") -AnnotationAssertion(rdfs:label "glutamine family amino acid biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (glycoprotein metabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving glycoproteins, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide.") -AnnotationAssertion( "glycoprotein metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0009100") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "glycoprotein metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (glycoprotein biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of glycoproteins, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide.") -AnnotationAssertion( "glycoprotein anabolism") -AnnotationAssertion( "glycoprotein biosynthesis") -AnnotationAssertion( "glycoprotein formation") -AnnotationAssertion( "glycoprotein synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0009101") -AnnotationAssertion(rdfs:label "glycoprotein biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (nucleobase metabolic process) - -AnnotationAssertion(Annotation( "GOC:ma") "The chemical reactions and pathways involving a nucleobase, a nitrogenous base that is a constituent of a nucleic acid, e.g. the purines: adenine, guanine, hypoxanthine, xanthine and the pyrimidines: cytosine, uracil, thymine.") -AnnotationAssertion( "nucleobase metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0009112") -AnnotationAssertion(rdfs:label "nucleobase metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (purine nucleobase biosynthetic process) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of purine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, which include adenine and guanine.") -AnnotationAssertion( "MetaCyc:PWY-841") -AnnotationAssertion( "purine base anabolism") -AnnotationAssertion( "purine base biosynthesis") -AnnotationAssertion(Annotation( "GOC:go_curators") "purine base biosynthetic process") -AnnotationAssertion( "purine base formation") -AnnotationAssertion( "purine base synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0009113") -AnnotationAssertion(rdfs:label "purine nucleobase biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (nucleoside metabolic process) - -AnnotationAssertion(Annotation( "GOC:ma") "The chemical reactions and pathways involving a nucleoside, a nucleobase linked to either beta-D-ribofuranose (a ribonucleoside) or 2-deoxy-beta-D-ribofuranose, (a deoxyribonucleoside), e.g. adenosine, guanosine, inosine, cytidine, uridine and deoxyadenosine, deoxyguanosine, deoxycytidine and thymidine (= deoxythymidine).") -AnnotationAssertion( "nucleoside metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0009116") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "nucleoside metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (nucleotide metabolic process) - -AnnotationAssertion(Annotation( "GOC:ma") "The chemical reactions and pathways involving a nucleotide, a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety; may be mono-, di- or triphosphate; this definition includes cyclic nucleotides (nucleoside cyclic phosphates).") -AnnotationAssertion( "nucleotide metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0009117") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "nucleotide metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of nucleoside metabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleosides.") -AnnotationAssertion( "regulation of nucleoside metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0009118") -AnnotationAssertion(rdfs:label "regulation of nucleoside metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (ribonucleoside metabolic process) - -AnnotationAssertion(Annotation( "GOC:jl") "The chemical reactions and pathways involving any ribonucleoside, a nucleoside in which purine or pyrimidine base is linked to a ribose (beta-D-ribofuranose) molecule.") -AnnotationAssertion( "ribonucleoside metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0009119") -AnnotationAssertion(rdfs:label "ribonucleoside metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (nucleoside diphosphate metabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving a nucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with diphosphate on the sugar.") -AnnotationAssertion( "nucleoside diphosphate metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0009132") -AnnotationAssertion(rdfs:label "nucleoside diphosphate metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (nucleoside diphosphate biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of a nucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with diphosphate on the sugar.") -AnnotationAssertion( "nucleoside diphosphate anabolism") -AnnotationAssertion( "nucleoside diphosphate biosynthesis") -AnnotationAssertion( "nucleoside diphosphate formation") -AnnotationAssertion( "nucleoside diphosphate synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0009133") -AnnotationAssertion(rdfs:label "nucleoside diphosphate biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (nucleoside diphosphate catabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of a nucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with diphosphate on the sugar.") -AnnotationAssertion( "nucleoside diphosphate breakdown") -AnnotationAssertion( "nucleoside diphosphate catabolism") -AnnotationAssertion( "nucleoside diphosphate degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0009134") -AnnotationAssertion(rdfs:label "nucleoside diphosphate catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (purine nucleoside diphosphate metabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving purine nucleoside diphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with diphosphate on the sugar.") -AnnotationAssertion( "purine nucleoside diphosphate metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0009135") -AnnotationAssertion(rdfs:label "purine nucleoside diphosphate metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (purine nucleoside diphosphate biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of purine nucleoside diphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with diphosphate on the sugar.") -AnnotationAssertion( "purine nucleoside diphosphate anabolism") -AnnotationAssertion( "purine nucleoside diphosphate biosynthesis") -AnnotationAssertion( "purine nucleoside diphosphate formation") -AnnotationAssertion( "purine nucleoside diphosphate synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0009136") -AnnotationAssertion(rdfs:label "purine nucleoside diphosphate biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (purine nucleoside diphosphate catabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of purine nucleoside diphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with diphosphate on the sugar.") -AnnotationAssertion( "purine nucleoside diphosphate breakdown") -AnnotationAssertion( "purine nucleoside diphosphate catabolism") -AnnotationAssertion( "purine nucleoside diphosphate degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0009137") -AnnotationAssertion(rdfs:label "purine nucleoside diphosphate catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (nucleoside triphosphate metabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving a nucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with triphosphate on the sugar.") -AnnotationAssertion( "nucleoside triphosphate metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0009141") -AnnotationAssertion(rdfs:label "nucleoside triphosphate metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (nucleoside triphosphate biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of a nucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with triphosphate on the sugar.") -AnnotationAssertion( "nucleoside triphosphate anabolism") -AnnotationAssertion( "nucleoside triphosphate biosynthesis") -AnnotationAssertion( "nucleoside triphosphate formation") -AnnotationAssertion( "nucleoside triphosphate synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0009142") -AnnotationAssertion(rdfs:label "nucleoside triphosphate biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (nucleoside triphosphate catabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of a nucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with triphosphate on the sugar.") -AnnotationAssertion( "nucleoside triphosphate breakdown") -AnnotationAssertion( "nucleoside triphosphate catabolism") -AnnotationAssertion( "nucleoside triphosphate degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0009143") -AnnotationAssertion(rdfs:label "nucleoside triphosphate catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (purine nucleoside triphosphate metabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving purine nucleoside triphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar.") -AnnotationAssertion( "purine nucleoside triphosphate metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0009144") -AnnotationAssertion(rdfs:label "purine nucleoside triphosphate metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (purine nucleoside triphosphate biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of purine nucleoside triphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar.") -AnnotationAssertion( "purine nucleoside triphosphate anabolism") -AnnotationAssertion( "purine nucleoside triphosphate biosynthesis") -AnnotationAssertion( "purine nucleoside triphosphate formation") -AnnotationAssertion( "purine nucleoside triphosphate synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0009145") -AnnotationAssertion(rdfs:label "purine nucleoside triphosphate biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (purine nucleoside triphosphate catabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of purine nucleoside triphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar.") -AnnotationAssertion( "purine nucleoside triphosphate breakdown") -AnnotationAssertion( "purine nucleoside triphosphate catabolism") -AnnotationAssertion( "purine nucleoside triphosphate degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0009146") -AnnotationAssertion(rdfs:label "purine nucleoside triphosphate catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (purine ribonucleotide metabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving a purine ribonucleotide, a compound consisting of ribonucleoside (a purine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.") -AnnotationAssertion( "purine ribonucleotide metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0009150") -AnnotationAssertion(rdfs:label "purine ribonucleotide metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (purine ribonucleotide biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of a purine ribonucleotide, a compound consisting of ribonucleoside (a purine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.") -AnnotationAssertion( "purine ribonucleotide anabolism") -AnnotationAssertion( "purine ribonucleotide biosynthesis") -AnnotationAssertion( "purine ribonucleotide formation") -AnnotationAssertion( "purine ribonucleotide synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0009152") -AnnotationAssertion(rdfs:label "purine ribonucleotide biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (purine ribonucleotide catabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of a purine ribonucleotide, a compound consisting of ribonucleoside (a purine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.") -AnnotationAssertion( "purine ribonucleotide breakdown") -AnnotationAssertion( "purine ribonucleotide catabolism") -AnnotationAssertion( "purine ribonucleotide degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0009154") -AnnotationAssertion(rdfs:label "purine ribonucleotide catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (nucleoside biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0140512713") "The chemical reactions and pathways resulting in the formation of any one of a family of organic molecules consisting of a purine or pyrimidine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside).") -AnnotationAssertion( "nucleoside anabolism") -AnnotationAssertion( "nucleoside biosynthesis") -AnnotationAssertion( "nucleoside formation") -AnnotationAssertion( "nucleoside synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0009163") -AnnotationAssertion(rdfs:label "nucleoside biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (nucleoside catabolic process) - -AnnotationAssertion(Annotation( "GOC:jl") "The chemical reactions and pathways resulting in the breakdown of any one of a family of organic molecules consisting of a purine or pyrimidine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside).") -AnnotationAssertion( "nucleoside breakdown") -AnnotationAssertion( "nucleoside catabolism") -AnnotationAssertion( "nucleoside degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0009164") -AnnotationAssertion(rdfs:label "nucleoside catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (nucleotide biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways resulting in the formation of nucleotides, any nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety; may be mono-, di- or triphosphate; this definition includes cyclic-nucleotides (nucleoside cyclic phosphates).") -AnnotationAssertion( "nucleotide anabolism") -AnnotationAssertion( "nucleotide biosynthesis") -AnnotationAssertion( "nucleotide formation") -AnnotationAssertion( "nucleotide synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0009165") -AnnotationAssertion(rdfs:label "nucleotide biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (nucleotide catabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways resulting in the breakdown of nucleotides, any nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety; may be mono-, di- or triphosphate; this definition includes cyclic-nucleotides (nucleoside cyclic phosphates).") -AnnotationAssertion( "nucleotide breakdown") -AnnotationAssertion( "nucleotide catabolism") -AnnotationAssertion( "nucleotide degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0009166") -AnnotationAssertion(rdfs:label "nucleotide catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (purine ribonucleoside diphosphate metabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving purine ribonucleoside diphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with diphosphate on the sugar.") -AnnotationAssertion( "purine ribonucleoside diphosphate metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0009179") -AnnotationAssertion(rdfs:label "purine ribonucleoside diphosphate metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (purine ribonucleoside diphosphate biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of purine ribonucleoside diphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with diphosphate on the sugar.") -AnnotationAssertion( "purine ribonucleoside diphosphate anabolism") -AnnotationAssertion( "purine ribonucleoside diphosphate biosynthesis") -AnnotationAssertion( "purine ribonucleoside diphosphate formation") -AnnotationAssertion( "purine ribonucleoside diphosphate synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0009180") -AnnotationAssertion(rdfs:label "purine ribonucleoside diphosphate biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (purine ribonucleoside diphosphate catabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of purine ribonucleoside diphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with diphosphate on the sugar.") -AnnotationAssertion( "purine ribonucleoside diphosphate breakdown") -AnnotationAssertion( "purine ribonucleoside diphosphate catabolism") -AnnotationAssertion( "purine ribonucleoside diphosphate degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0009181") -AnnotationAssertion(rdfs:label "purine ribonucleoside diphosphate catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (ribonucleoside diphosphate metabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving a ribonucleoside diphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with diphosphate on the sugar.") -AnnotationAssertion( "ribonucleoside diphosphate metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0009185") -AnnotationAssertion(rdfs:label "ribonucleoside diphosphate metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (ribonucleoside diphosphate biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of a ribonucleoside diphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with diphosphate on the sugar.") -AnnotationAssertion( "ribonucleoside diphosphate anabolism") -AnnotationAssertion( "ribonucleoside diphosphate biosynthesis") -AnnotationAssertion( "ribonucleoside diphosphate formation") -AnnotationAssertion( "ribonucleoside diphosphate synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0009188") -AnnotationAssertion(rdfs:label "ribonucleoside diphosphate biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (ribonucleoside diphosphate catabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of a ribonucleoside diphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with diphosphate on the sugar.") -AnnotationAssertion( "ribonucleoside diphosphate breakdown") -AnnotationAssertion( "ribonucleoside diphosphate catabolism") -AnnotationAssertion( "ribonucleoside diphosphate degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0009191") -AnnotationAssertion(rdfs:label "ribonucleoside diphosphate catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (ribonucleoside triphosphate metabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving a ribonucleoside triphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with triphosphate on the sugar.") -AnnotationAssertion( "ribonucleoside triphosphate metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0009199") -AnnotationAssertion(rdfs:label "ribonucleoside triphosphate metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (ribonucleoside triphosphate biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of a ribonucleoside triphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with triphosphate on the sugar.") -AnnotationAssertion( "ribonucleoside triphosphate anabolism") -AnnotationAssertion( "ribonucleoside triphosphate biosynthesis") -AnnotationAssertion( "ribonucleoside triphosphate formation") -AnnotationAssertion( "ribonucleoside triphosphate synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0009201") -AnnotationAssertion(rdfs:label "ribonucleoside triphosphate biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (ribonucleoside triphosphate catabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of a ribonucleoside triphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with triphosphate on the sugar.") -AnnotationAssertion( "ribonucleoside triphosphate breakdown") -AnnotationAssertion( "ribonucleoside triphosphate catabolism") -AnnotationAssertion( "ribonucleoside triphosphate degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0009203") -AnnotationAssertion(rdfs:label "ribonucleoside triphosphate catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (purine ribonucleoside triphosphate metabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving purine ribonucleoside triphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with triphosphate on the sugar.") -AnnotationAssertion( "purine ribonucleoside triphosphate metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0009205") -AnnotationAssertion(rdfs:label "purine ribonucleoside triphosphate metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (purine ribonucleoside triphosphate biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of purine ribonucleoside triphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with triphosphate on the sugar.") -AnnotationAssertion( "purine ribonucleoside triphosphate anabolism") -AnnotationAssertion( "purine ribonucleoside triphosphate biosynthesis") -AnnotationAssertion( "purine ribonucleoside triphosphate formation") -AnnotationAssertion( "purine ribonucleoside triphosphate synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0009206") -AnnotationAssertion(rdfs:label "purine ribonucleoside triphosphate biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (purine ribonucleoside triphosphate catabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of purine ribonucleoside triphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with triphosphate on the sugar.") -AnnotationAssertion( "purine ribonucleoside triphosphate breakdown") -AnnotationAssertion( "purine ribonucleoside triphosphate catabolism") -AnnotationAssertion( "purine ribonucleoside triphosphate degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0009207") -AnnotationAssertion(rdfs:label "purine ribonucleoside triphosphate catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (glycolipid biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways resulting in the formation of glycolipid, a class of 1,2-di-O-acylglycerols joined at oxygen 3 by a glycosidic linkage to a carbohydrate part (usually a mono-, di- or tri-saccharide).") -AnnotationAssertion( "MetaCyc:PWY-401") -AnnotationAssertion( "glycolipid anabolism") -AnnotationAssertion( "glycolipid biosynthesis") -AnnotationAssertion( "glycolipid formation") -AnnotationAssertion( "glycolipid synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0009247") -AnnotationAssertion(rdfs:label "glycolipid biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - # Class: (glucan biosynthetic process) AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways resulting in the formation of glucans, polysaccharides consisting only of glucose residues.") @@ -60419,54 +22566,9 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0009250") AnnotationAssertion(rdfs:label "glucan biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) -# Class: (glucan catabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways resulting in the breakdown of glucans, polysaccharides consisting only of glucose residues.") -AnnotationAssertion( "glucan breakdown") -AnnotationAssertion( "glucan catabolism") -AnnotationAssertion( "glucan degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0009251") -AnnotationAssertion(rdfs:label "glucan catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (ribonucleotide metabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving a ribonucleotide, a compound consisting of ribonucleoside (a base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.") -AnnotationAssertion( "GO:0009121") -AnnotationAssertion( "ribonucleotide metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0009259") -AnnotationAssertion(rdfs:label "ribonucleotide metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (ribonucleotide biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of a ribonucleotide, a compound consisting of ribonucleoside (a base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.") -AnnotationAssertion( "ribonucleotide anabolism") -AnnotationAssertion( "ribonucleotide biosynthesis") -AnnotationAssertion( "ribonucleotide formation") -AnnotationAssertion( "ribonucleotide synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0009260") -AnnotationAssertion(rdfs:label "ribonucleotide biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (ribonucleotide catabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of a ribonucleotide, a compound consisting of ribonucleoside (a base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.") -AnnotationAssertion( "ribonucleotide breakdown") -AnnotationAssertion( "ribonucleotide catabolism") -AnnotationAssertion( "ribonucleotide degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0009261") -AnnotationAssertion(rdfs:label "ribonucleotide catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (response to temperature stimulus) AnnotationAssertion(Annotation( "GOC:hb") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a temperature stimulus.") @@ -60487,7 +22589,6 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0009306") AnnotationAssertion(rdfs:label "protein secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) @@ -60504,31 +22605,6 @@ AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "amine metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (amine biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom.") -AnnotationAssertion( "amine anabolism") -AnnotationAssertion( "amine biosynthesis") -AnnotationAssertion( "amine formation") -AnnotationAssertion( "amine synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0009309") -AnnotationAssertion(rdfs:label "amine biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (amine catabolic process) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom.") -AnnotationAssertion( "amine breakdown") -AnnotationAssertion( "amine catabolism") -AnnotationAssertion( "amine degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0009310") -AnnotationAssertion(rdfs:label "amine catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (response to radiation) @@ -60541,44 +22617,6 @@ AnnotationAssertion(rdfs:comment "No AnnotationAssertion(rdfs:label "response to radiation") SubClassOf( ) -# Class: (phospholipid catabolic process) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of phospholipids, any lipid containing phosphoric acid as a mono- or diester.") -AnnotationAssertion( "phospholipid breakdown") -AnnotationAssertion( "phospholipid catabolism") -AnnotationAssertion( "phospholipid degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0009395") -AnnotationAssertion(rdfs:label "phospholipid catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (response to water deprivation) - -AnnotationAssertion(Annotation( "GOC:lr") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a water deprivation stimulus, prolonged deprivation of water.") -AnnotationAssertion( "response to dehydration") -AnnotationAssertion( "response to drought") -AnnotationAssertion( "response to thirst") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "drought tolerance") -AnnotationAssertion( "GO:0009414") -AnnotationAssertion(rdfs:label "response to water deprivation") -SubClassOf( ) -SubClassOf( ) - -# Class: (response to water) - -AnnotationAssertion(Annotation( "GOC:jl") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of water.") -AnnotationAssertion(Annotation( "GOC:dos") "response to water stimulus") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0009415") -AnnotationAssertion(rdfs:label "response to water") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - # Class: (response to light stimulus) AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0582227089") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light.") @@ -60586,7 +22624,6 @@ AnnotationAssertion( "GO:0009416") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "response to light stimulus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) # Class: (gamma-aminobutyric acid metabolic process) @@ -60603,48 +22640,9 @@ AnnotationAssertion( "GO:0009448") AnnotationAssertion(rdfs:comment "See also the biological process term 'neurotransmitter metabolic process ; GO:0042133'.") AnnotationAssertion(rdfs:label "gamma-aminobutyric acid metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) -# Class: (gamma-aminobutyric acid biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways resulting in the formation of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms.") -AnnotationAssertion( "4-aminobutanoate biosynthesis") -AnnotationAssertion( "4-aminobutanoate biosynthetic process") -AnnotationAssertion( "4-aminobutyrate biosynthesis") -AnnotationAssertion( "4-aminobutyrate biosynthetic process") -AnnotationAssertion( "GABA biosynthesis") -AnnotationAssertion( "GABA biosynthetic process") -AnnotationAssertion( "gamma-aminobutyric acid anabolism") -AnnotationAssertion( "gamma-aminobutyric acid biosynthesis") -AnnotationAssertion( "gamma-aminobutyric acid formation") -AnnotationAssertion( "gamma-aminobutyric acid synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0009449") -AnnotationAssertion(rdfs:comment "See also the biological process term 'neurotransmitter biosynthetic process ; GO:0042136'.") -AnnotationAssertion(rdfs:label "gamma-aminobutyric acid biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (gamma-aminobutyric acid catabolic process) - -AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways resulting in the breakdown of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms.") -AnnotationAssertion( "MetaCyc:4AMINOBUTMETAB-PWY") -AnnotationAssertion( "4-aminobutanoate catabolic process") -AnnotationAssertion( "4-aminobutanoate catabolism") -AnnotationAssertion( "4-aminobutyrate catabolic process") -AnnotationAssertion( "4-aminobutyrate catabolism") -AnnotationAssertion( "GABA catabolic process") -AnnotationAssertion( "GABA catabolism") -AnnotationAssertion( "gamma-aminobutyric acid breakdown") -AnnotationAssertion( "gamma-aminobutyric acid catabolism") -AnnotationAssertion( "gamma-aminobutyric acid degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0009450") -AnnotationAssertion(rdfs:comment "See also the biological process term 'neurotransmitter catabolic process ; GO:0042135'.") -AnnotationAssertion(rdfs:label "gamma-aminobutyric acid catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (fertilization) AnnotationAssertion(Annotation( "GOC:tb") Annotation( "ISBN:0198506732") "The union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy).") @@ -60654,7 +22652,6 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0009566") AnnotationAssertion(rdfs:label "fertilization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf( ObjectSomeValuesFrom( )) # Class: (detection of external stimulus) @@ -60770,29 +22767,6 @@ AnnotationAssertion(rdfs:label "resp SubClassOf( ) SubClassOf( ) -# Class: (response to bacterium) - -AnnotationAssertion(Annotation( "GOC:hb") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a bacterium.") -AnnotationAssertion( "GO:0009618") -AnnotationAssertion( "GO:0009680") -AnnotationAssertion( "response to bacteria") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0009617") -AnnotationAssertion(rdfs:label "response to bacterium") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (response to fungus) - -AnnotationAssertion(Annotation( "GOC:hb") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a fungus.") -AnnotationAssertion( "GO:0009621") -AnnotationAssertion( "response to fungi") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0009620") -AnnotationAssertion(rdfs:label "response to fungus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - # Class: (response to abiotic stimulus) AnnotationAssertion(Annotation( "GOC:hb") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abiotic (not derived from living organisms) stimulus.") @@ -60841,7 +22815,6 @@ AnnotationAssertion(rdfs:label "anat SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) DisjointClasses( ) -DisjointClasses( ) # Class: (catechol-containing compound metabolic process) @@ -60851,89 +22824,8 @@ AnnotationAssertion( "catechol metabolism") AnnotationAssertion( "GO:0009712") AnnotationAssertion(rdfs:label "catechol-containing compound metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (catechol-containing compound biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways resulting in the formation of catechol-containing compounds. Catechol is a compound containing a pyrocatechol nucleus or substituent.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "catechol anabolism") -AnnotationAssertion( "catechol biosynthesis") -AnnotationAssertion( "catechol biosynthetic process") -AnnotationAssertion( "catechol formation") -AnnotationAssertion( "catechol synthesis") -AnnotationAssertion( "GO:0009713") -AnnotationAssertion(rdfs:label "catechol-containing compound biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (response to endogenous stimulus) - -AnnotationAssertion(Annotation( "GOC:sm") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus arising within the organism.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0009719") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.") -AnnotationAssertion(rdfs:label "response to endogenous stimulus") -SubClassOf( ) - -# Class: (response to hormone) - -AnnotationAssertion(Annotation( "GOC:jl") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hormone stimulus.") -AnnotationAssertion(Annotation( "GOC:dos") "response to hormone stimulus") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "growth regulator") -AnnotationAssertion( "GO:0009725") -AnnotationAssertion(rdfs:label "response to hormone") -SubClassOf( ) -SubClassOf( ) - -# Class: (response to carbohydrate) - -AnnotationAssertion(Annotation( "GOC:jl") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbohydrate stimulus.") -AnnotationAssertion(Annotation( "GOC:dos") "response to carbohydrate stimulus") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0009743") -AnnotationAssertion(rdfs:label "response to carbohydrate") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (response to hexose) - -AnnotationAssertion(Annotation( "GOC:jl") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hexose stimulus.") -AnnotationAssertion(Annotation( "GOC:dos") "response to hexose stimulus") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0009746") -AnnotationAssertion(rdfs:label "response to hexose") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (response to glucose) - -AnnotationAssertion(Annotation( "GOC:jl") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucose stimulus.") -AnnotationAssertion(Annotation( "GOC:dos") "response to glucose stimulus") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0009749") -AnnotationAssertion(rdfs:label "response to glucose") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (hormone-mediated signaling pathway) - -AnnotationAssertion(Annotation( "GOC:sm") "The series of molecular signals mediated by the detection of a hormone.") -AnnotationAssertion( "hormone mediated signalling") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0009755") -AnnotationAssertion(rdfs:label "hormone-mediated signaling pathway") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (regulation of asymmetric cell division) - -AnnotationAssertion(Annotation( "GOC:lr") "Any process that modulates the frequency, rate or extent of asymmetric cell division.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0009786") -AnnotationAssertion(rdfs:label "regulation of asymmetric cell division") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (embryo development) AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "GOC:isa_complete") Annotation( "GOC:mtg_sensu") "The process whose specific outcome is the progression of an embryo from its formation until the end of its embryonic life stage. The end of the embryonic stage is organism-specific. For example, for mammals, the process would begin with zygote formation and end with birth. For insects, the process would begin at zygote formation and end with larval hatching. For plant zygotic embryos, this would be from zygote formation to the end of seed dormancy. For plant vegetative embryos, this would be from the initial determination of the cell or group of cells to form an embryo until the point when the embryo becomes independent of the parent plant.") @@ -60948,7 +22840,6 @@ AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "embryo development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ) @@ -60974,73 +22865,6 @@ SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectAllValuesFrom( )) -# Class: (axis specification) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:go_curators") Annotation( "GOC:isa_complete") "The establishment, maintenance and elaboration of a pattern along a line or around a point.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "axis determination") -AnnotationAssertion( "GO:0009798") -AnnotationAssertion(rdfs:label "axis specification") -SubClassOf( ) - -# Class: (alkaloid metabolic process) - -AnnotationAssertion(Annotation( "GOC:lr") Annotation( "ISBN:0122146743") "The chemical reactions and pathways involving alkaloids, nitrogen containing natural products which are not otherwise classified as peptides, nonprotein amino acids, amines, cyanogenic glycosides, glucosinolates, cofactors, phytohormones or primary metabolites (such as purine or pyrimidine bases).") -AnnotationAssertion( "alkaloid metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0009820") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "alkaloid metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (alkaloid biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:lr") Annotation( "ISBN:0122146743") "The chemical reactions and pathways resulting in the formation of alkaloids, nitrogen-containing natural products which are not otherwise classified as nonprotein amino acids, amines, peptides, amines, cyanogenic glycosides, glucosinolates, cofactors, phytohormones, or primary metabolite (such as purine or pyrimidine bases).") -AnnotationAssertion( "UM-BBD_enzymeID:e0711") -AnnotationAssertion( "alkaloid anabolism") -AnnotationAssertion( "alkaloid biosynthesis") -AnnotationAssertion( "alkaloid formation") -AnnotationAssertion( "alkaloid synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0009821") -AnnotationAssertion(rdfs:label "alkaloid biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (alkaloid catabolic process) - -AnnotationAssertion(Annotation( "GOC:lr") Annotation( "ISBN:0122146743") "The chemical reactions and pathways resulting in the breakdown of alkaloids, nitrogen containing natural products not otherwise classified as peptides, nonprotein amino acids, amines, cyanogenic glycosides, glucosinolates, cofactors, phytohormones or primary metabolites (such as purine or pyrimidine bases).") -AnnotationAssertion( "alkaloid breakdown") -AnnotationAssertion( "alkaloid catabolism") -AnnotationAssertion( "alkaloid degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0009822") -AnnotationAssertion(rdfs:label "alkaloid catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (embryonic pattern specification) - -AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0521436125") "The process that results in the patterns of cell differentiation that will arise in an embryo.") -AnnotationAssertion( "embryonic pattern biosynthesis") -AnnotationAssertion( "embryonic pattern formation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "ventral/lateral system") -AnnotationAssertion( "GO:0009880") -AnnotationAssertion(rdfs:label "embryonic pattern specification") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (post-embryonic animal morphogenesis) - -AnnotationAssertion(Annotation( "GOC:go_curators") "The process, occurring after animal embryonic development, by which anatomical structures are generated and organized.") -AnnotationAssertion( "post-embryonic morphogenesis of an anatomical structure") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0009886") -AnnotationAssertion(rdfs:label "post-embryonic animal morphogenesis") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (animal organ morphogenesis) AnnotationAssertion(Annotation( "GOC:dgh") Annotation( "GOC:go_curators") Annotation( "ISBN:0471245208") Annotation( "ISBN:0721662544") "Morphogenesis of an animal organ. An organ is defined as a tissue or set of tissues that work together to perform a specific function or functions. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.") @@ -61048,7 +22872,6 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0009887") AnnotationAssertion(rdfs:label "animal organ morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) @@ -61067,7 +22890,6 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0009888") AnnotationAssertion(rdfs:label "tissue development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) @@ -61087,139 +22909,6 @@ DisjointClasses( ObjectSomeValuesFrom DisjointClasses( ObjectSomeValuesFrom( )) DisjointClasses( ObjectSomeValuesFrom( )) -# Class: (regulation of biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances.") -AnnotationAssertion( "regulation of anabolism") -AnnotationAssertion( "regulation of biosynthesis") -AnnotationAssertion( "regulation of formation") -AnnotationAssertion( "regulation of synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0009889") -AnnotationAssertion(rdfs:label "regulation of biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (negative regulation of biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the rate of the chemical reactions and pathways resulting in the formation of substances.") -AnnotationAssertion( "down regulation of biosynthetic process") -AnnotationAssertion( "down-regulation of biosynthetic process") -AnnotationAssertion( "downregulation of biosynthetic process") -AnnotationAssertion( "negative regulation of anabolism") -AnnotationAssertion( "negative regulation of biosynthesis") -AnnotationAssertion( "negative regulation of formation") -AnnotationAssertion( "negative regulation of synthesis") -AnnotationAssertion( "inhibition of biosynthetic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0009890") -AnnotationAssertion(rdfs:label "negative regulation of biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances.") -AnnotationAssertion( "positive regulation of anabolism") -AnnotationAssertion( "positive regulation of biosynthesis") -AnnotationAssertion( "positive regulation of formation") -AnnotationAssertion( "positive regulation of synthesis") -AnnotationAssertion( "up regulation of biosynthetic process") -AnnotationAssertion( "up-regulation of biosynthetic process") -AnnotationAssertion( "upregulation of biosynthetic process") -AnnotationAssertion( "activation of biosynthetic process") -AnnotationAssertion( "stimulation of biosynthetic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0009891") -AnnotationAssertion(rdfs:label "positive regulation of biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of metabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.") -AnnotationAssertion( "GO:0044252") -AnnotationAssertion( "down regulation of metabolic process") -AnnotationAssertion( "down-regulation of metabolic process") -AnnotationAssertion( "downregulation of metabolic process") -AnnotationAssertion( "negative regulation of metabolism") -AnnotationAssertion( "negative regulation of organismal metabolism") -AnnotationAssertion( "inhibition of metabolic process") -AnnotationAssertion( "inhibition of organismal metabolic process") -AnnotationAssertion( "negative regulation of multicellular organismal metabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0009892") -AnnotationAssertion(rdfs:label "negative regulation of metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of metabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.") -AnnotationAssertion( "GO:0044253") -AnnotationAssertion( "positive regulation of metabolism") -AnnotationAssertion( "up regulation of metabolic process") -AnnotationAssertion( "up-regulation of metabolic process") -AnnotationAssertion( "upregulation of metabolic process") -AnnotationAssertion( "activation of metabolic process") -AnnotationAssertion( "positive regulation of multicellular organismal metabolic process") -AnnotationAssertion( "positive regulation of organismal metabolism") -AnnotationAssertion( "stimulation of metabolic process") -AnnotationAssertion( "stimulation of organismal metabolic process") -AnnotationAssertion( "up-regulation of organismal metabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0009893") -AnnotationAssertion(rdfs:label "positive regulation of metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of catabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of substances.") -AnnotationAssertion( "regulation of breakdown") -AnnotationAssertion( "regulation of catabolism") -AnnotationAssertion( "regulation of degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0009894") -AnnotationAssertion(rdfs:label "regulation of catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (negative regulation of catabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances.") -AnnotationAssertion( "down regulation of catabolic process") -AnnotationAssertion( "down-regulation of catabolic process") -AnnotationAssertion( "downregulation of catabolic process") -AnnotationAssertion( "negative regulation of breakdown") -AnnotationAssertion( "negative regulation of catabolism") -AnnotationAssertion( "negative regulation of degradation") -AnnotationAssertion( "inhibition of catabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0009895") -AnnotationAssertion(rdfs:label "negative regulation of catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of catabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances.") -AnnotationAssertion( "positive regulation of breakdown") -AnnotationAssertion( "positive regulation of catabolism") -AnnotationAssertion( "positive regulation of degradation") -AnnotationAssertion( "up regulation of catabolic process") -AnnotationAssertion( "up-regulation of catabolic process") -AnnotationAssertion( "upregulation of catabolic process") -AnnotationAssertion( "activation of catabolic process") -AnnotationAssertion( "stimulation of catabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0009896") -AnnotationAssertion(rdfs:label "positive regulation of catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - # Class: (epidermal cell differentiation) AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:go_curators") Annotation( "GOC:mtg_sensu") Annotation( "GOC:sdb_2009") Annotation( "GOC:tb") "The process in which a relatively unspecialized cell acquires specialized features of an epidermal cell, any of the cells making up the epidermis.") @@ -61228,7 +22917,6 @@ AnnotationAssertion( "GOC:kmv") Annotation( "GOC:rk") "hypodermal cell differentiation") AnnotationAssertion( "GO:0009913") AnnotationAssertion(rdfs:label "epidermal cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) @@ -61242,78 +22930,6 @@ AnnotationAssertion(rdfs:label "horm SubClassOf( ) SubClassOf( ) -# Class: (anterior/posterior axis specification) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:go_curators") Annotation( "GOC:tb") "The establishment, maintenance and elaboration of the anterior/posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism.") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") "anterior/posterior axis determination") -AnnotationAssertion( "GO:0009948") -AnnotationAssertion(rdfs:label "anterior/posterior axis specification") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (anterior/posterior pattern specification) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:go_curators") Annotation( "GOC:isa_complete") Annotation( "GOC:tb") "The regionalization process in which specific areas of cell differentiation are determined along the anterior-posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "anterior/posterior pattern formation") -AnnotationAssertion( "GO:0009952") -AnnotationAssertion(rdfs:label "anterior/posterior pattern specification") -SubClassOf( ) - -# Class: (regulation of signal transduction) - -AnnotationAssertion(Annotation( "GOC:sm") "Any process that modulates the frequency, rate or extent of signal transduction.") -AnnotationAssertion( "GO:0035466") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "regulation of signaling pathway") -AnnotationAssertion(Annotation( "GOC:mah") "regulation of signalling pathway") -AnnotationAssertion( "GO:0009966") -AnnotationAssertion(rdfs:label "regulation of signal transduction") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of signal transduction) - -AnnotationAssertion(Annotation( "GOC:sm") "Any process that activates or increases the frequency, rate or extent of signal transduction.") -AnnotationAssertion( "GO:0035468") -AnnotationAssertion( "up regulation of signal transduction") -AnnotationAssertion( "up-regulation of signal transduction") -AnnotationAssertion( "upregulation of signal transduction") -AnnotationAssertion( "activation of signal transduction") -AnnotationAssertion( "stimulation of signal transduction") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "positive regulation of signaling pathway") -AnnotationAssertion(Annotation( "GOC:mah") "positive regulation of signalling pathway") -AnnotationAssertion( "GO:0009967") -AnnotationAssertion(rdfs:label "positive regulation of signal transduction") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of signal transduction) - -AnnotationAssertion(Annotation( "GOC:sm") "Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction.") -AnnotationAssertion( "GO:0035467") -AnnotationAssertion( "down regulation of signal transduction") -AnnotationAssertion( "down-regulation of signal transduction") -AnnotationAssertion( "downregulation of signal transduction") -AnnotationAssertion( "inhibition of signal transduction") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "negative regulation of signaling pathway") -AnnotationAssertion(Annotation( "GOC:mah") "negative regulation of signalling pathway") -AnnotationAssertion( "GO:0009968") -AnnotationAssertion(rdfs:label "negative regulation of signal transduction") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - # Class: (cellular process) AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "GOC:isa_complete") "Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.") @@ -61335,75 +22951,6 @@ AnnotationAssertion(rdfs:label "cell SubClassOf( ) DisjointClasses( ) -# Class: (intracellular water homeostasis) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "A homeostatic process involved in the maintenance of a steady state level of water within a cell.") -AnnotationAssertion( "cellular water homeostasis") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "cellular osmoregulation") -AnnotationAssertion( "GO:0009992") -AnnotationAssertion(rdfs:label "intracellular water homeostasis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (oocyte differentiation) - -AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "GOC:mtg_sensu") "The process in which a relatively unspecialized immature germ cell acquires the specialized features of a mature female gamete.") -AnnotationAssertion( "oocyte cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0009994") -AnnotationAssertion(rdfs:label "oocyte differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (glial cell differentiation) - -AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "GOC:mtg_sensu") "The process in which a relatively unspecialized cell acquires the specialized features of a glial cell.") -AnnotationAssertion( "GO:0007404") -AnnotationAssertion( "GO:0043360") -AnnotationAssertion( "glia cell differentiation") -AnnotationAssertion( "neuroglia differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010001") -AnnotationAssertion(rdfs:label "glial cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - -# Class: (cardioblast differentiation) - -AnnotationAssertion(Annotation( "GOC:go_curators") "The process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.") -AnnotationAssertion(Annotation( "GOC:mtg_heart") "cardiac precursor cell differentiation") -AnnotationAssertion( "cardioblast cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "cardiomyocyte generation") -AnnotationAssertion( "GO:0010002") -AnnotationAssertion(rdfs:label "cardioblast differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (gastrulation involving germ band extension) - -AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "GOC:mtg_sensu") "A complex and coordinated series of cellular movements, including germ band extension, that occurs at the end of cleavage during embryonic development. An example of this process is found in Drosophila melanogaster.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010004") -AnnotationAssertion(rdfs:label "gastrulation involving germ band extension") -SubClassOf( ) - -# Class: (meiotic chromosome condensation) - -AnnotationAssertion(Annotation( "PMID:10072401") "Compaction of chromatin structure prior to meiosis in eukaryotic cells.") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "chromosome condensation involved in meiotic cell cycle") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010032") -AnnotationAssertion(rdfs:label "meiotic chromosome condensation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - # Class: (response to organic substance) AnnotationAssertion(Annotation( "GOC:sm") Annotation( "PMID:23356676") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic substance stimulus.") @@ -61412,180 +22959,6 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0010033") AnnotationAssertion(rdfs:label "response to organic substance") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (response to acetate) - -AnnotationAssertion(Annotation( "GOC:sm") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetate stimulus.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010034") -AnnotationAssertion(rdfs:label "response to acetate") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (response to inorganic substance) - -AnnotationAssertion(Annotation( "GOC:sm") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inorganic substance stimulus.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010035") -AnnotationAssertion(rdfs:label "response to inorganic substance") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (response to carbon dioxide) - -AnnotationAssertion(Annotation( "GOC:sm") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbon dioxide (CO2) stimulus.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010037") -AnnotationAssertion(rdfs:label "response to carbon dioxide") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (response to metal ion) - -AnnotationAssertion(Annotation( "GOC:sm") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metal ion stimulus.") -AnnotationAssertion( "response to metal") -AnnotationAssertion( "response to heavy metal") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "heavy metal sensitivity/resistance") -AnnotationAssertion( "GO:0010038") -AnnotationAssertion(rdfs:label "response to metal ion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (response to iron ion) - -AnnotationAssertion(Annotation( "GOC:sm") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron ion stimulus.") -AnnotationAssertion( "response to iron") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010039") -AnnotationAssertion(rdfs:label "response to iron ion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (zygote asymmetric cell division) - -AnnotationAssertion(Annotation( "GOC:tb") "The division of the zygote into two daughter cells that will adopt developmentally distinct potentials.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "zygote asymmetric cytokinesis") -AnnotationAssertion( "GO:0010070") -AnnotationAssertion(rdfs:label "zygote asymmetric cell division") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (formation of animal organ boundary) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:isa_complete") Annotation( "PMID:9611175") "The regionalization process that specifies animal organ primordium boundaries resulting in a restriction of organogenesis to a limited spatial domain and keeping the organ separate from surrounding tissues.") -AnnotationAssertion( "GO:0048862") -AnnotationAssertion( "organ boundary specification") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010160") -AnnotationAssertion(rdfs:label "formation of animal organ boundary") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (body morphogenesis) - -AnnotationAssertion(Annotation( "GOC:ems") Annotation( "ISBN:0140512888") "The process in which the anatomical structures of the soma are generated and organized.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010171") -AnnotationAssertion(rdfs:label "body morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (response to chitin) - -AnnotationAssertion(Annotation( "GOC:sm") "A process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chitin stimulus.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010200") -AnnotationAssertion(rdfs:label "response to chitin") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (vascular transport) - -AnnotationAssertion(Annotation( "GOC:sm") "The directed movement of substances, into, out of or within a cell, either in a vascular tissue or in the vascular membrane.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010232") -AnnotationAssertion(rdfs:label "vascular transport") -SubClassOf( ) -SubClassOf( ) - -# Class: (response to organonitrogen compound) - -AnnotationAssertion(Annotation( "PMID:9869419") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organonitrogen stimulus. An organonitrogen compound is formally a compound containing at least one carbon-nitrogen bond.") -AnnotationAssertion( "response to organic nitrogen") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010243") -AnnotationAssertion(rdfs:label "response to organonitrogen compound") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (endomembrane system organization) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:sm") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endomembrane system.") -AnnotationAssertion( "endomembrane organization") -AnnotationAssertion(Annotation( "GOC:mah") "endomembrane system organisation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010256") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "endomembrane system organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (membrane invagination) - -AnnotationAssertion(Annotation( "GOC:tb") "The infolding of a membrane.") -AnnotationAssertion( "jl") -AnnotationAssertion( "2013-12-02T13:58:34Z") -AnnotationAssertion( "GO:1902534") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "single-organism membrane invagination") -AnnotationAssertion( "GO:0010324") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "membrane invagination") -SubClassOf( ) - -# Class: (regulation of cell fate commitment) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the frequency, rate or extent of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010453") -AnnotationAssertion(rdfs:label "regulation of cell fate commitment") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of cell fate commitment) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that stops, prevents or reduces the frequency or rate of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010454") -AnnotationAssertion(rdfs:label "negative regulation of cell fate commitment") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (positive regulation of cell fate commitment) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that activates, maintains or increases the frequency or rate of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010455") -AnnotationAssertion(rdfs:label "positive regulation of cell fate commitment") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (cell proliferation in dorsal spinal cord) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "The multiplication or reproduction of cells, resulting in the expansion of the dorsal spinal cord cell population.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010456") -AnnotationAssertion(rdfs:label "cell proliferation in dorsal spinal cord") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (mesenchymal cell proliferation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010463") -AnnotationAssertion(rdfs:label "mesenchymal cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) # Class: (regulation of mesenchymal cell proliferation) @@ -61593,7 +22966,6 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:0010464") AnnotationAssertion(rdfs:label "regulation of mesenchymal cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) # Class: (gene expression) @@ -61608,846 +22980,14 @@ AnnotationAssertion( "gene expression") SubClassOf( ) -# Class: (regulation of gene expression) - -AnnotationAssertion(Annotation( "GOC:txnOH-2018") "Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA).") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/22557"^^xsd:anyURI) -AnnotationAssertion( "Wikipedia:Regulation_of_gene_expression") -AnnotationAssertion( "regulation of protein expression") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:cjm") "gene regulation") -AnnotationAssertion( "regulation of gene product expression") -AnnotationAssertion( "GO:0010468") -AnnotationAssertion(rdfs:comment "This class covers any process that regulates the rate of production of a mature gene product, and so includes processes that regulate that rate by regulating the level, stability or availability of intermediates in the process of gene expression. For example, it covers any process that regulates the level, stability or availability of mRNA or circRNA for translation and thereby regulates the rate of production of the encoded protein via translation.") -AnnotationAssertion(rdfs:label "regulation of gene expression") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of signaling receptor activity) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the frequency, rate or extent of a signaling receptor activity. Receptor activity is when a molecule combines with an extracellular or intracellular messenger to initiate a change in cell activity.") -AnnotationAssertion( "regulation of receptor activity") -AnnotationAssertion( "regulation of signalling receptor activity") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010469") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "regulation of signaling receptor activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of gastrulation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the rate or extent of gastrulation. Gastrulation is the complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010470") -AnnotationAssertion(rdfs:label "regulation of gastrulation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (epidermal cell division) - -AnnotationAssertion(Annotation( "PMID:17450124") "Any process resulting in the physical partitioning and separation of an epidermal cell, any of the cells making up the epidermis, into daughter cells.") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:kmv") Annotation( "GOC:rk") "hypodermal cell division") -AnnotationAssertion( "GO:0010481") -AnnotationAssertion(rdfs:label "epidermal cell division") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of epidermal cell division) - -AnnotationAssertion(Annotation( "PMID:17450124") "Any process that modulates the frequency, rate or extent of the physical partitioning and separation of an epidermal cell into daughter cells. An epidermal cell is any of the cells that make up the epidermis.") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:kmv") Annotation( "GOC:rk") "regulation of hypodermal cell division") -AnnotationAssertion( "GO:0010482") -AnnotationAssertion(rdfs:label "regulation of epidermal cell division") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (intercellular transport) - -AnnotationAssertion(Annotation( "GOC:dhl") "The movement of substances between cells.") -AnnotationAssertion( "jl") -AnnotationAssertion( "2013-12-19T13:24:56Z") -AnnotationAssertion( "GO:1902585") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "single organism intercellular transport") -AnnotationAssertion( "single-organism intercellular transport") -AnnotationAssertion( "GO:0010496") -AnnotationAssertion(rdfs:label "intercellular transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of platelet activation) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010543") -AnnotationAssertion(rdfs:label "regulation of platelet activation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of platelet activation) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that decreases the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010544") -AnnotationAssertion(rdfs:label "negative regulation of platelet activation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of membrane disassembly) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the frequency, rate or extent of membrane disassembly.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010549") -AnnotationAssertion(rdfs:label "regulation of membrane disassembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of macromolecule biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010556") -AnnotationAssertion(rdfs:label "regulation of macromolecule biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of macromolecule biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that increases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010557") -AnnotationAssertion(rdfs:label "positive regulation of macromolecule biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of macromolecule biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that decreases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010558") -AnnotationAssertion(rdfs:label "negative regulation of macromolecule biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of glycoprotein biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010559") -AnnotationAssertion(rdfs:label "regulation of glycoprotein biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of glycoprotein biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that increases the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010560") -AnnotationAssertion(rdfs:label "positive regulation of glycoprotein biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of glycoprotein biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that decreases the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010561") -AnnotationAssertion(rdfs:label "negative regulation of glycoprotein biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of phosphorus metabolic process) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010562") -AnnotationAssertion(rdfs:label "positive regulation of phosphorus metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of phosphorus metabolic process) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010563") -AnnotationAssertion(rdfs:label "negative regulation of phosphorus metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of cell cycle process) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010564") -AnnotationAssertion(rdfs:label "regulation of cell cycle process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of cellular ketone metabolic process) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the chemical reactions and pathways involving any of a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010565") -AnnotationAssertion(rdfs:label "regulation of cellular ketone metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of ketone biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of a ketone, carried out by individual cells.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010566") -AnnotationAssertion(rdfs:label "regulation of ketone biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of ketone catabolic process) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a ketone, carried out by individual cells.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010567") -AnnotationAssertion(rdfs:label "regulation of ketone catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of platelet activation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:sl") Annotation( "GOC:tb") "Any process that increases the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010572") -AnnotationAssertion(rdfs:label "positive regulation of platelet activation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of endothelial cell migration) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010594") -AnnotationAssertion(rdfs:label "regulation of endothelial cell migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of endothelial cell migration) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that increases the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010595") -AnnotationAssertion(rdfs:label "positive regulation of endothelial cell migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of endothelial cell migration) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that decreases the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010596") -AnnotationAssertion(rdfs:label "negative regulation of endothelial cell migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of macromolecule metabolic process) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010604") -AnnotationAssertion(rdfs:label "positive regulation of macromolecule metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of macromolecule metabolic process) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010605") -AnnotationAssertion(rdfs:label "negative regulation of macromolecule metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (post-transcriptional regulation of gene expression) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the frequency, rate or extent of gene expression after the production of an RNA transcript.") -AnnotationAssertion( "posttranscriptional regulation of gene expression") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010608") -AnnotationAssertion(rdfs:label "post-transcriptional regulation of gene expression") -SubClassOf( ) - -# Class: (regulation of cardiac muscle hypertrophy) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010611") -AnnotationAssertion(rdfs:label "regulation of cardiac muscle hypertrophy") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of cardiac muscle adaptation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the rate, extent or frequency of the process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010612") -AnnotationAssertion(rdfs:label "regulation of cardiac muscle adaptation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of cardiac muscle hypertrophy) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that increases the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010613") -AnnotationAssertion(rdfs:label "positive regulation of cardiac muscle hypertrophy") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of cardiac muscle hypertrophy) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that decreases the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010614") -AnnotationAssertion(rdfs:label "negative regulation of cardiac muscle hypertrophy") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of cardiac muscle adaptation) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that increases the rate, extent or frequency of the process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010615") -AnnotationAssertion(rdfs:label "positive regulation of cardiac muscle adaptation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of cardiac muscle adaptation) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that decreases the rate, extent or frequency of the process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010616") -AnnotationAssertion(rdfs:label "negative regulation of cardiac muscle adaptation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (programmed cell death involved in cell development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:tb") "The activation of endogenous cellular processes that result in the death of a cell as part of its development.") -AnnotationAssertion( "developmental programmed cell death") -AnnotationAssertion( "programmed cell death involved in development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010623") -AnnotationAssertion(rdfs:comment "This process is part of the natural developmental program of some cell types, but it does not always happen as part of the development or shaping of a gross anatomical structure.") -AnnotationAssertion(rdfs:label "programmed cell death involved in cell development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of Schwann cell proliferation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:sl") Annotation( "GOC:tb") "Any process that modulates the frequency or rate of multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010624") -AnnotationAssertion(rdfs:label "regulation of Schwann cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of Schwann cell proliferation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:sl") Annotation( "GOC:tb") "Any process that increases the frequency or rate of the multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010625") -AnnotationAssertion(rdfs:label "positive regulation of Schwann cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of Schwann cell proliferation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:sl") Annotation( "GOC:tb") "Any process that decreases the frequency or extent of the multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010626") -AnnotationAssertion(rdfs:label "negative regulation of Schwann cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of gene expression) - -AnnotationAssertion(Annotation( "GOC:txnOH-2018") "Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA).") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/22557"^^xsd:anyURI) -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010628") -AnnotationAssertion(rdfs:label "positive regulation of gene expression") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of gene expression) - -AnnotationAssertion(Annotation( "GOC:txnOH-2018") "Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA).") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/22557"^^xsd:anyURI) -AnnotationAssertion( "biological_process") -AnnotationAssertion( "gene silencing") -AnnotationAssertion( "GO:0010629") -AnnotationAssertion(rdfs:comment "This term covers any process that negatively regulates the rate of production of a mature gene product, and so includes processes that negatively regulate that rate by reducing the level, stability or availability of intermediates in the process of gene expression. For example, it covers any process that reduces the level, stability or availability of mRNA or circRNA for translation and thereby reduces the rate of production of the encoded protein via translation.") -AnnotationAssertion(rdfs:label "negative regulation of gene expression") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (epithelial cell migration) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "The orderly movement of an epithelial cell from one site to another, often during the development of a multicellular organism.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010631") -AnnotationAssertion(rdfs:label "epithelial cell migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (regulation of epithelial cell migration) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the frequency, rate or extent of epithelial cell migration.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010632") -AnnotationAssertion(rdfs:label "regulation of epithelial cell migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (negative regulation of epithelial cell migration) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that stops, prevents, or reduces the frequency, rate or extent of epithelial cell migration.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010633") -AnnotationAssertion(rdfs:label "negative regulation of epithelial cell migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of epithelial cell migration) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that activates or increases the frequency, rate or extent of epithelial cell migration.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010634") -AnnotationAssertion(rdfs:label "positive regulation of epithelial cell migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of organelle organization) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle.") -AnnotationAssertion(Annotation( "GOC:mah") "positive regulation of organelle organisation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:mah") "positive regulation of organelle organization and biogenesis") -AnnotationAssertion( "GO:0010638") -AnnotationAssertion(rdfs:label "positive regulation of organelle organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of organelle organization) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that decreases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle.") -AnnotationAssertion(Annotation( "GOC:mah") "negative regulation of organelle organisation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:mah") "negative regulation of organelle organization and biogenesis") -AnnotationAssertion( "GO:0010639") -AnnotationAssertion(rdfs:label "negative regulation of organelle organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - # Class: (regulation of cell communication) AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0010646") AnnotationAssertion(rdfs:label "regulation of cell communication") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (positive regulation of cell communication) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that increases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010647") -AnnotationAssertion(rdfs:label "positive regulation of cell communication") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of cell communication) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that decreases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010648") -AnnotationAssertion(rdfs:label "negative regulation of cell communication") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of muscle cell apoptotic process) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:tb") "Any process that decreases the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death.") -AnnotationAssertion( "negative regulation of muscle cell apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010656") -AnnotationAssertion(rdfs:label "negative regulation of muscle cell apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (muscle cell apoptotic process) - -AnnotationAssertion(Annotation( "CL:0000187") Annotation( "GOC:dph") Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:tb") "A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a muscle cell and result in its death. A muscle cell is a mature contractile cell, commonly known as a myocyte, that forms one of three kinds of muscle.") -AnnotationAssertion( "muscle cell apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010657") -AnnotationAssertion(rdfs:label "muscle cell apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - -# Class: (striated muscle cell apoptotic process) - -AnnotationAssertion(Annotation( "CL:0000737") Annotation( "GOC:dph") Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:tb") "A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a striated muscle cell and result in its death. Striated muscle cells make up striated muscle fibers which are divided by transverse bands into striations.") -AnnotationAssertion( "striated muscle cell apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010658") -AnnotationAssertion(rdfs:label "striated muscle cell apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (cardiac muscle cell apoptotic process) - -AnnotationAssertion(Annotation( "CL:0000746") Annotation( "GOC:dph") Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:tb") "A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a cardiac muscle cell and result in its death. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction.") -AnnotationAssertion( "cardiac muscle cell apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010659") -AnnotationAssertion(rdfs:label "cardiac muscle cell apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of muscle cell apoptotic process) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:tb") "Any process that modulates the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death.") -AnnotationAssertion( "regulation of muscle cell apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010660") -AnnotationAssertion(rdfs:label "regulation of muscle cell apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of muscle cell apoptotic process) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:tb") "Any process that increases the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death.") -AnnotationAssertion( "positive regulation of muscle cell apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010661") -AnnotationAssertion(rdfs:label "positive regulation of muscle cell apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of striated muscle cell apoptotic process) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:tb") "Any process that modulates the rate or extent of striated muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a striated muscle cell and result in its death.") -AnnotationAssertion( "regulation of striated muscle cell apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010662") -AnnotationAssertion(rdfs:label "regulation of striated muscle cell apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of striated muscle cell apoptotic process) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:tb") "Any process that increases the rate or extent of striated muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a striated muscle cell and result in its death.") -AnnotationAssertion( "positive regulation of striated muscle cell apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010663") -AnnotationAssertion(rdfs:label "positive regulation of striated muscle cell apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of striated muscle cell apoptotic process) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:rl") Annotation( "GOC:tb") "Any process that decreases the rate or extent of striated muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a striated muscle cell and result in its death.") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:rl") Annotation( "GOC:tb") "down regulation of striated muscle cell apoptosis") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:rl") Annotation( "GOC:tb") "down-regulation of striated muscle cell apoptosis") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:rl") Annotation( "GOC:tb") "downregulation of striated muscle cell apoptosis") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:rl") Annotation( "GOC:tb") "inhibition of striated muscle cell apoptosis") -AnnotationAssertion( "negative regulation of striated muscle cell apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010664") -AnnotationAssertion(rdfs:label "negative regulation of striated muscle cell apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of cardiac muscle cell apoptotic process) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:tb") "Any process that modulates the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death.") -AnnotationAssertion( "regulation of cardiac muscle cell apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010665") -AnnotationAssertion(rdfs:label "regulation of cardiac muscle cell apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of cardiac muscle cell apoptotic process) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:tb") "Any process that increases the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death.") -AnnotationAssertion( "positive regulation of cardiac muscle cell apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010666") -AnnotationAssertion(rdfs:label "positive regulation of cardiac muscle cell apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of cardiac muscle cell apoptotic process) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:rl") Annotation( "GOC:tb") "Any process that decreases the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death.") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:rl") Annotation( "GOC:tb") "down regulation of cardiac muscle cell apoptosis") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:rl") Annotation( "GOC:tb") "down-regulation of cardiac muscle cell apoptosis") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:rl") Annotation( "GOC:tb") "downregulation of cardiac muscle cell apoptosis") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:rl") Annotation( "GOC:tb") "inhibition of cardiac muscle cell apoptosis") -AnnotationAssertion( "negative regulation of cardiac muscle cell apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010667") -AnnotationAssertion(rdfs:label "negative regulation of cardiac muscle cell apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (ectodermal cell differentiation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "The process in which relatively unspecialized cells acquire specialized structural and/or functional features of an ectodermal cell. Differentiation includes the processes involved in commitment of a cell to a specific fate.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010668") -AnnotationAssertion(rdfs:label "ectodermal cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (negative regulation of norepinephrine secretion) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that decreases the frequency, rate or extent of the regulated release of norepinephrine.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010700") -AnnotationAssertion(rdfs:label "negative regulation of norepinephrine secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of norepinephrine secretion) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that increases the frequency, rate or extent of the regulated release of norepinephrine.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010701") -AnnotationAssertion(rdfs:label "positive regulation of norepinephrine secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of collagen catabolic process) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the rate, frequency or extent of collagen catabolism. Collagen catabolism is the proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix.") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "regulation of collagen breakdown") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "regulation of collagen catabolism") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "regulation of collagen degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010710") -AnnotationAssertion(rdfs:label "regulation of collagen catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of collagen catabolic process) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that decreases the rate, frequency or extent of collagen catabolism. Collagen catabolism is the proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix.") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "down regulation of collagen catabolic process") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "down-regulation of collagen catabolic process") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "downregulation of collagen catabolic process") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "negative regulation of collagen breakdown") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "negative regulation of collagen catabolism") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "negative regulation of collagen degradation") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "inhibition of collagen catabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010711") -AnnotationAssertion(rdfs:label "negative regulation of collagen catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of collagen metabolic process) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals.") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "regulation of collagen metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010712") -AnnotationAssertion(rdfs:label "regulation of collagen metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of collagen metabolic process) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010713") -AnnotationAssertion(rdfs:label "negative regulation of collagen metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of collagen metabolic process) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals.") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "positive regulation of collagen metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010714") -AnnotationAssertion(rdfs:label "positive regulation of collagen metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of extracellular matrix disassembly) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix.") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "regulation of extracellular matrix breakdown") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "regulation of extracellular matrix degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010715") -AnnotationAssertion(rdfs:label "regulation of extracellular matrix disassembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of extracellular matrix disassembly) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that decreases the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix.") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "down regulation of extracellular matrix disassembly") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "down-regulation of extracellular matrix disassembly") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "downregulation of extracellular matrix disassembly") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "negative regulation of extracellular matrix breakdown") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "negative regulation of extracellular matrix degradation") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "inhibition of extracellular matrix disassembly") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010716") -AnnotationAssertion(rdfs:label "negative regulation of extracellular matrix disassembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of epithelial to mesenchymal transition) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010717") -AnnotationAssertion(rdfs:label "regulation of epithelial to mesenchymal transition") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of epithelial to mesenchymal transition) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that increases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition is where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010718") -AnnotationAssertion(rdfs:label "positive regulation of epithelial to mesenchymal transition") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (negative regulation of epithelial to mesenchymal transition) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that decreases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010719") -AnnotationAssertion(rdfs:label "negative regulation of epithelial to mesenchymal transition") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of cell development) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that increases the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010720") -AnnotationAssertion(rdfs:label "positive regulation of cell development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of cell development) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that decreases the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010721") -AnnotationAssertion(rdfs:label "negative regulation of cell development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of macrophage chemotaxis) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the rate, frequency or extent of macrophage chemotaxis. Macrophage chemotaxis is the movement of a macrophage in response to an external stimulus.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010758") -AnnotationAssertion(rdfs:label "regulation of macrophage chemotaxis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of macrophage chemotaxis) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that increases the rate, frequency or extent of macrophage chemotaxis. Macrophage chemotaxis is the movement of a macrophage in response to an external stimulus.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010759") -AnnotationAssertion(rdfs:label "positive regulation of macrophage chemotaxis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of macrophage chemotaxis) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that decreases the rate, frequency or extent of macrophage chemotaxis. Macrophage chemotaxis is the movement of a macrophage in response to an external stimulus.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010760") -AnnotationAssertion(rdfs:label "negative regulation of macrophage chemotaxis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (fibroblast migration) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:tb") "Cell migration that is accomplished by extension and retraction of a fibroblast pseudopodium. A fibroblast is a connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules.") -AnnotationAssertion(Annotation( "GOC:dph") "fibroblast cell migration") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010761") -AnnotationAssertion(rdfs:label "fibroblast migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of fibroblast migration) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium.") -AnnotationAssertion(Annotation( "GOC:dph") "regulation of fibroblast cell migration") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010762") -AnnotationAssertion(rdfs:label "regulation of fibroblast migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of fibroblast migration) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that increases the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium.") -AnnotationAssertion(Annotation( "GOC:dph") "positive regulation of fibroblast cell migration") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010763") -AnnotationAssertion(rdfs:label "positive regulation of fibroblast migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of fibroblast migration) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that decreases the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium.") -AnnotationAssertion(Annotation( "GOC:dph") "negative regulation of fibroblast cell migration") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010764") -AnnotationAssertion(rdfs:label "negative regulation of fibroblast migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of sodium ion transport) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that increases the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010765") -AnnotationAssertion(rdfs:label "positive regulation of sodium ion transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of sodium ion transport) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that decreases the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010766") -AnnotationAssertion(rdfs:label "negative regulation of sodium ion transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of cell morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that increases the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/24299"^^xsd:anyURI) -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010770") -AnnotationAssertion(rdfs:label "positive regulation of cell morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (negative regulation of cell morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that decreases the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/24299"^^xsd:anyURI) -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010771") -AnnotationAssertion(rdfs:label "negative regulation of cell morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (calcitonin catabolic process) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:rl") "The chemical reactions and pathways resulting in the breakdown of the peptide calcitonin.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010816") -AnnotationAssertion(rdfs:label "calcitonin catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - # Class: (regulation of hormone levels) AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the levels of hormone within an organism or a tissue. A hormone is any substance formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells in the same organism, upon which it has a specific regulatory action.") @@ -62455,127 +22995,6 @@ AnnotationAssertion( "GO:0010817") AnnotationAssertion(rdfs:label "regulation of hormone levels") -# Class: (T cell chemotaxis) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "The directed movement of a T cell in response to an external stimulus. A T cell is a type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex.") -AnnotationAssertion(Annotation( "CL:0000084") "T-cell chemotaxis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010818") -AnnotationAssertion(rdfs:label "T cell chemotaxis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of T cell chemotaxis) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the rate, frequency or extent of T cell chemotaxis. T cell chemotaxis is the directed movement of a T cell in response to an external stimulus.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010819") -AnnotationAssertion(rdfs:label "regulation of T cell chemotaxis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of T cell chemotaxis) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that increases the rate, frequency or extent of T cell chemotaxis. T cell chemotaxis is the directed movement of a T cell in response to an external stimulus.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010820") -AnnotationAssertion(rdfs:label "positive regulation of T cell chemotaxis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of glucose transmembrane transport) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the frequency, rate or extent of glucose transport across a membrane. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "regulation of glucose transport") -AnnotationAssertion( "GO:0010827") -AnnotationAssertion(rdfs:label "regulation of glucose transmembrane transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of glucose transmembrane transport) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that increases the frequency, rate or extent of glucose transport across a membrane. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "positive regulation of glucose transport") -AnnotationAssertion( "GO:0010828") -AnnotationAssertion(rdfs:label "positive regulation of glucose transmembrane transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of glucose transmembrane transport) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that decreases the frequency, rate or extent of glucose transport across a membrane. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "negative regulation of glucose transport") -AnnotationAssertion( "GO:0010829") -AnnotationAssertion(rdfs:label "negative regulation of glucose transmembrane transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of myotube differentiation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010830") -AnnotationAssertion(rdfs:label "regulation of myotube differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of myotube differentiation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that activates, maintains or increases the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010831") -AnnotationAssertion(rdfs:label "positive regulation of myotube differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of myotube differentiation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that decreases the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010832") -AnnotationAssertion(rdfs:label "negative regulation of myotube differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of keratinocyte proliferation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the rate, frequency or extent of keratinocyte proliferation. Keratinocyte proliferation is the multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010837") -AnnotationAssertion(rdfs:label "regulation of keratinocyte proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (positive regulation of keratinocyte proliferation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that increases the rate, frequency or extent of keratinocyte proliferation. Keratinocyte proliferation is the multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010838") -AnnotationAssertion(rdfs:label "positive regulation of keratinocyte proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of keratinocyte proliferation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that decreases the rate, frequency or extent of keratinocyte proliferation. Keratinocyte proliferation is the multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010839") -AnnotationAssertion(rdfs:label "negative regulation of keratinocyte proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (retina layer formation) - -AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") Annotation( "PMID:1270266") "The process in which the vertebrate retina is organized into three laminae: the outer nuclear layer (ONL), which contains photoreceptor nuclei; the inner nuclear layer (INL), which contains amacrine, bipolar and horizontal cells; and the retinal ganglion cell (RGC) layer. Between the inner and outer nuclear layers, the outer plexiform layer (OPL) contains connections between the photoreceptors and bipolar and horizontal cells. The inner plexiform layer (IPL) is positioned between the INL and the ganglion cell layer and contains the dendrites of RGCs and processes of bipolar and amacrine cells. Spanning all layers of the retina are the radially oriented Mueller glia.") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "retinal lamination") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "retinal layer formation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010842") -AnnotationAssertion(rdfs:label "retina layer formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (lipid localization) AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process in which a lipid is transported to, or maintained in, a specific location.") @@ -62583,282 +23002,8 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:0010876") AnnotationAssertion(rdfs:label "lipid localization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (positive regulation of steroid biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:tb") "Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010893") -AnnotationAssertion(rdfs:label "positive regulation of steroid biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of steroid biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:tb") "Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010894") -AnnotationAssertion(rdfs:label "negative regulation of steroid biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of glucose metabolic process) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:tb") "Any process that modulates the rate, frequency or extent of glucose metabolism. Glucose metabolic processes are the chemical reactions and pathways involving glucose, the aldohexose gluco-hexose.") -AnnotationAssertion(Annotation( "GOC:tb") "regulation of glucose metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010906") -AnnotationAssertion(rdfs:label "regulation of glucose metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (positive regulation of glucose metabolic process) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:tb") "Any process that increases the rate, frequency or extent of glucose metabolism. Glucose metabolic processes are the chemical reactions and pathways involving glucose, the aldohexose gluco-hexose.") -AnnotationAssertion(Annotation( "GOC:tb") "positive regulation of glucose metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010907") -AnnotationAssertion(rdfs:label "positive regulation of glucose metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (cellular component assembly involved in morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "The cellular component assembly that is part of the initial shaping of the component during its developmental progression.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010927") -AnnotationAssertion(rdfs:label "cellular component assembly involved in morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (macrophage cytokine production) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:rl") Annotation( "GOC:tb") "The appearance of a macrophage cytokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010934") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.") -AnnotationAssertion(rdfs:label "macrophage cytokine production") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of macrophage cytokine production) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:rl") "Any process that modulates the rate, frequency or extent of macrophage cytokine production. Macrophage cytokine production is the appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010935") -AnnotationAssertion(rdfs:label "regulation of macrophage cytokine production") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of macrophage cytokine production) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:rl") "Any process that decreases the rate, frequency or extent of macrophage cytokine production. Macrophage cytokine production is the appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010936") -AnnotationAssertion(rdfs:label "negative regulation of macrophage cytokine production") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of cytoplasmic microtubule depolymerization) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the frequency, rate or extent of cytoplasmic microtubule depolymerization.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010937") -AnnotationAssertion(rdfs:label "regulation of cytoplasmic microtubule depolymerization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cytoplasmic microtubule depolymerization) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "The removal of tubulin heterodimers from one or both ends of a cytoplasmic microtubule.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010938") -AnnotationAssertion(rdfs:label "cytoplasmic microtubule depolymerization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (negative regulation of cell cycle process) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that decreases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2009-04-27T09:53:22Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010948") -AnnotationAssertion(rdfs:label "negative regulation of cell cycle process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (positive regulation of protein processing) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mah") Annotation( "GOC:tb") "Any process that increases the rate, frequency or extent of protein maturation by peptide bond cleavage.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2009-04-27T12:09:13Z") -AnnotationAssertion(Annotation( "GOC:bf") "positive regulation of protein maturation by peptide bond cleavage") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010954") -AnnotationAssertion(rdfs:label "positive regulation of protein processing") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (negative regulation of protein processing) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mah") Annotation( "GOC:tb") "Any process that decreases the rate, frequency or extent of protein maturation by peptide bond cleavage.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2009-04-27T12:10:19Z") -AnnotationAssertion(Annotation( "GOC:bf") "negative regulation of protein maturation by peptide bond cleavage") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010955") -AnnotationAssertion(rdfs:label "negative regulation of protein processing") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of amino acid import across plasma membrane) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the frequency, rate or extent of amino acid import into a cell.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2009-05-06T11:33:12Z") -AnnotationAssertion( "regulation of amino acid import") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010958") -AnnotationAssertion(rdfs:label "regulation of amino acid import across plasma membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of metal ion transport) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the frequency, rate, or extent of metal ion transport. Metal ion transport is the directed movement of metal ions, any metal ion with an electric charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2009-05-06T11:40:55Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010959") -AnnotationAssertion(rdfs:label "regulation of metal ion transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of glucan biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the rate, frequency, or extent of glucan biosynthesis. Glucan biosynthetic processes are the chemical reactions and pathways resulting in the formation of glucans, polysaccharides consisting only of glucose residues.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2009-05-11T12:17:53Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010962") -AnnotationAssertion(rdfs:label "regulation of glucan biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of phosphate transport) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the frequency, rate or extent of phosphate transport. Phosphate transport is the directed movement of phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2009-05-20T11:42:50Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010966") -AnnotationAssertion(rdfs:label "regulation of phosphate transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of microtubule nucleation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the rate, frequency or extent of microtubule nucleation. Microtubule nucleation is the 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2009-05-20T11:51:21Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010968") -AnnotationAssertion(rdfs:label "regulation of microtubule nucleation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (transport along microtubule) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mah") Annotation( "GOC:tb") "The movement of organelles or other particles from one location in the cell to another along microtubules, driven by motor activity.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2009-05-27T10:56:08Z") -AnnotationAssertion( "microtubule-based transport") -AnnotationAssertion(Annotation( "GOC:dph") "establishment of localization by movement along microtubule") -AnnotationAssertion( "movement along microtubule") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010970") -AnnotationAssertion(rdfs:label "transport along microtubule") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of neuron projection development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).") -AnnotationAssertion( "tb") -AnnotationAssertion( "2009-06-01T10:44:45Z") -AnnotationAssertion(Annotation( "GOC:mah") "regulation of neurite biosynthesis") -AnnotationAssertion(Annotation( "GOC:mah") "regulation of neurite development") -AnnotationAssertion(Annotation( "GOC:mah") "regulation of neurite formation") -AnnotationAssertion(Annotation( "GOC:mah") "regulation of neurite growth") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010975") -AnnotationAssertion(rdfs:label "regulation of neuron projection development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of neuron projection development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that increases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).") -AnnotationAssertion( "tb") -AnnotationAssertion( "2009-06-01T10:46:44Z") -AnnotationAssertion(Annotation( "GOC:mah") "positive regulation of neurite biosynthesis") -AnnotationAssertion(Annotation( "GOC:mah") "positive regulation of neurite development") -AnnotationAssertion(Annotation( "GOC:mah") "positive regulation of neurite formation") -AnnotationAssertion(Annotation( "GOC:mah") "positive regulation of neurite growth") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0010976") -AnnotationAssertion(rdfs:label "positive regulation of neuron projection development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of neuron projection development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that decreases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).") -AnnotationAssertion( "tb") -AnnotationAssertion( "2009-06-01T10:47:42Z") -AnnotationAssertion(Annotation( "GOC:mah") "negative regulation of neurite biosynthesis") -AnnotationAssertion(Annotation( "GOC:mah") "negative regulation of neurite development") -AnnotationAssertion(Annotation( "GOC:mah") "negative regulation of neurite formation") -AnnotationAssertion(Annotation( "GOC:mah") "negative regulation of neurite growth") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:pr") "growth cone collapse") -AnnotationAssertion( "GO:0010977") -AnnotationAssertion(rdfs:label "negative regulation of neuron projection development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (programmed cell death) - -AnnotationAssertion(Annotation( "GOC:lr") Annotation( "GOC:mtg_apoptosis") "A process which begins when a cell receives an internal or external signal and activates a series of biochemical events (signaling pathway). The process ends with the death of the cell.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/24835"^^xsd:anyURI) -AnnotationAssertion( "GO:0016244") -AnnotationAssertion( "regulated cell death") -AnnotationAssertion( "Wikipedia:Programmed_cell_death") -AnnotationAssertion( "caspase-independent cell death") -AnnotationAssertion( "non-apoptotic programmed cell death") -AnnotationAssertion( "nonapoptotic programmed cell death") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "PCD") -AnnotationAssertion( "RCD") -AnnotationAssertion( "caspase-independent apoptosis") -AnnotationAssertion( "GO:0012501") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "Note that this term should be used to annotate gene products in the organism undergoing the programmed cell death. To annotate genes in another organism whose products modulate programmed cell death in a host organism, consider the term 'modulation by symbiont of host programmed cell death ; GO:0052040'. Also, note that 'programmed cell death ; GO:0012501' should be used to refer to instances of caspase-independent cell death mechanisms, in the absence of further indications on the process taking place. At present, caspase-independent cell death is not yet represented in GO due to the lack of consensus and in-depth research on the topic. 'programmed cell death ; GO:0012501' may also be used to annotate gene products in taxa where apoptosis as defined in GO:0006915 does not occur, such as plants. You may also consider these specific children: GO:0097468 'programmed cell death in response to reactive oxygen species' (with descendants GO:0010421 'hydrogen peroxide-mediated programmed cell death' and GO:0010343 'singlet oxygen-mediated programmed cell death'), and GO:0009626 'plant-type hypersensitive response' and its children.") -AnnotationAssertion(rdfs:label "programmed cell death") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - # Class: (endomembrane system) AnnotationAssertion(Annotation( "GOC:lh") "A collection of membranous structures involved in transport within the cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles.") @@ -62881,100 +23026,6 @@ AnnotationAssertion( "cellular_component") AnnotationAssertion( "GO:0012506") AnnotationAssertion(rdfs:label "vesicle membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (astrocyte development) - -AnnotationAssertion(Annotation( "GOC:dgh") Annotation( "GOC:ef") "The process aimed at the progression of an astrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. An astrocyte is the most abundant type of glial cell. Astrocytes provide support for neurons and regulate the environment in which they function.") -AnnotationAssertion( "astrocyte cell development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0014002") -AnnotationAssertion(rdfs:label "astrocyte development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (oligodendrocyte development) - -AnnotationAssertion(Annotation( "GOC:dgh") Annotation( "GOC:ef") "The process aimed at the progression of an oligodendrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. An oligodendrocyte is a type of glial cell involved in myelinating the axons in the central nervous system.") -AnnotationAssertion( "oligodendrocyte cell development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0014003") -AnnotationAssertion(rdfs:label "oligodendrocyte development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (glial cell proliferation) - -AnnotationAssertion(Annotation( "GOC:ef") Annotation( "ISBN:0878932585") "The multiplication or reproduction of glial cells by cell division, resulting in the expansion of their population. Glial cells exist throughout the nervous system, and include Schwann cells, astrocytes, and oligodendrocytes among others.") -AnnotationAssertion( "glia proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0014009") -AnnotationAssertion(rdfs:label "glial cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (Schwann cell proliferation) - -AnnotationAssertion(Annotation( "GOC:ef") Annotation( "ISBN:0878932585") "The multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0014010") -AnnotationAssertion(rdfs:label "Schwann cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of gliogenesis) - -AnnotationAssertion(Annotation( "GOC:ef") "Any process that modulates the frequency, rate or extent of gliogenesis, the formation of mature glia.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0014013") -AnnotationAssertion(rdfs:label "regulation of gliogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of gliogenesis) - -AnnotationAssertion(Annotation( "GOC:ef") "Any process that stops, prevents, or reduces the frequency, rate or extent of gliogenesis, the formation of mature glia.") -AnnotationAssertion( "down regulation of gliogenesis") -AnnotationAssertion( "down-regulation of gliogenesis") -AnnotationAssertion( "downregulation of gliogenesis") -AnnotationAssertion( "inhibition of gliogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0014014") -AnnotationAssertion(rdfs:label "negative regulation of gliogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of gliogenesis) - -AnnotationAssertion(Annotation( "GOC:ef") "Any process that activates or increases the frequency, rate or extent of gliogenesis, the formation of mature glia.") -AnnotationAssertion( "up regulation of gliogenesis") -AnnotationAssertion( "up-regulation of gliogenesis") -AnnotationAssertion( "upregulation of gliogenesis") -AnnotationAssertion( "activation of gliogenesis") -AnnotationAssertion( "stimulation of gliogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0014015") -AnnotationAssertion(rdfs:label "positive regulation of gliogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (neuroblast differentiation) - -AnnotationAssertion(Annotation( "GOC:ef") Annotation( "ISBN:0878932585") "The process in which a relatively unspecialized cell acquires specialized features of a neuroblast. There are at least four stages through which the pluripotent cells of epiblast or blastula become neuroblasts.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0014016") -AnnotationAssertion(rdfs:label "neuroblast differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (neuroblast development) - -AnnotationAssertion(Annotation( "GOC:ef") Annotation( "ISBN:0878932585") "The process aimed at the progression of a neuroblast over time, from initial commitment of the cell to a specific state, to the mature neuroblast. It does not include processes where the neuroblast turns into a glial cell or a neuron.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0014019") -AnnotationAssertion(rdfs:label "neuroblast development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) # Class: (primary neural tube formation) @@ -62989,599 +23040,15 @@ AnnotationAssertion(rdfs:label "prim SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (neural rod formation) - -AnnotationAssertion(Annotation( "GOC:dh") Annotation( "GOC:ef") "The formation of a solid rod of neurectoderm derived from the neural keel. The neural rod is roughly circular in cross section. Neural rod formation occurs during primary neurulation in teleosts.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0014023") -AnnotationAssertion(rdfs:label "neural rod formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - -# Class: (neural keel formation) - -AnnotationAssertion(Annotation( "GOC:dh") Annotation( "GOC:ef") "The formation of a thickened region of the neurectoderm that is roughly triangular in cross section. The neural keel develops from the neural plate and develops into the neural rod. Neural keel formation occurs during primary neurulation in teleosts.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0014025") -AnnotationAssertion(rdfs:label "neural keel formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (notochord formation) - -AnnotationAssertion(Annotation( "GOC:dh") Annotation( "GOC:ef") "The formation of the notochord from the chordamesoderm. The notochord is composed of large cells packed within a firm connective tissue sheath and is found in all chordates at the ventral surface of the neural tube. In vertebrates, the notochord contributes to the vertebral column.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0014028") -AnnotationAssertion(rdfs:label "notochord formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (neural crest formation) - -AnnotationAssertion(Annotation( "GOC:dh") Annotation( "GOC:ef") "The formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation procedes.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0014029") -AnnotationAssertion(rdfs:label "neural crest formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (mesenchymal cell development) - -AnnotationAssertion(Annotation( "GOC:dh") Annotation( "GOC:ef") "The process aimed at the progression of a mesenchymal cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0014031") -AnnotationAssertion(rdfs:label "mesenchymal cell development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (neural crest cell development) - -AnnotationAssertion(Annotation( "GOC:dh") Annotation( "GOC:ef") "The process aimed at the progression of a neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0014032") -AnnotationAssertion(rdfs:label "neural crest cell development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (neural crest cell differentiation) - -AnnotationAssertion(Annotation( "GOC:dh") Annotation( "GOC:ef") "The process in which a relatively unspecialized cell acquires specialized features of a neural crest cell.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0014033") -AnnotationAssertion(rdfs:label "neural crest cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (Schwann cell differentiation) - -AnnotationAssertion(Annotation( "GOC:ef") "The process in which a relatively unspecialized cell acquires the specialized features of a Schwann cell. Schwann cells are found in the peripheral nervous system, where they insulate neurons and axons, and regulate the environment in which neurons function.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0014037") -AnnotationAssertion(rdfs:label "Schwann cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (regulation of Schwann cell differentiation) - -AnnotationAssertion(Annotation( "GOC:ef") "Any process that modulates the frequency, rate or extent of Schwann cell differentiation.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0014038") -AnnotationAssertion(rdfs:label "regulation of Schwann cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of Schwann cell differentiation) - -AnnotationAssertion(Annotation( "GOC:ef") "Any process that stops, prevents, or reduces the frequency, rate or extent of Schwann cell differentiation.") -AnnotationAssertion( "down regulation of Schwann cell differentiation") -AnnotationAssertion( "down-regulation of Schwann cell differentiation") -AnnotationAssertion( "downregulation of Schwann cell differentiation") -AnnotationAssertion( "inhibition of Schwann cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0014039") -AnnotationAssertion(rdfs:label "negative regulation of Schwann cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of Schwann cell differentiation) - -AnnotationAssertion(Annotation( "GOC:ef") "Any process that activates or increases the frequency, rate or extent of Schwann cell differentiation.") -AnnotationAssertion( "up regulation of Schwann cell differentiation") -AnnotationAssertion( "up-regulation of Schwann cell differentiation") -AnnotationAssertion( "upregulation of Schwann cell differentiation") -AnnotationAssertion( "activation of Schwann cell differentiation") -AnnotationAssertion( "stimulation of Schwann cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0014040") -AnnotationAssertion(rdfs:label "positive regulation of Schwann cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of neuron maturation) - -AnnotationAssertion(Annotation( "GOC:ef") "Any process that modulates the frequency, rate or extent of neuron maturation, the process leading to the attainment of the full functional capacity of a neuron. This process is independent of morphogenetic change.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0014041") -AnnotationAssertion(rdfs:label "regulation of neuron maturation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of neuron maturation) - -AnnotationAssertion(Annotation( "GOC:ef") "Any process that activates or increases the frequency, rate or extent of neuron maturation.") -AnnotationAssertion( "up regulation of neuron maturation") -AnnotationAssertion( "up-regulation of neuron maturation") -AnnotationAssertion( "upregulation of neuron maturation") -AnnotationAssertion( "activation of neuron maturation") -AnnotationAssertion( "stimulation of neuron maturation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0014042") -AnnotationAssertion(rdfs:label "positive regulation of neuron maturation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of neuron maturation) - -AnnotationAssertion(Annotation( "GOC:ef") "Any process that stops, prevents, or reduces the frequency, rate or extent of neuron maturation.") -AnnotationAssertion( "down regulation of neuron maturation") -AnnotationAssertion( "down-regulation of neuron maturation") -AnnotationAssertion( "downregulation of neuron maturation") -AnnotationAssertion( "inhibition of neuron maturation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0014043") -AnnotationAssertion(rdfs:label "negative regulation of neuron maturation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (Schwann cell development) - -AnnotationAssertion(Annotation( "GOC:dgh") Annotation( "GOC:ef") "The process aimed at the progression of a Schwann cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. Schwann cells are found in the peripheral nervous system, where they insulate neurons and axons, and regulate the environment in which neurons function.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0014044") -AnnotationAssertion(rdfs:label "Schwann cell development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (dopamine secretion) - -AnnotationAssertion(Annotation( "GOC:ef") "The regulated release of dopamine by a cell. Dopamine is a catecholamine and a precursor of adrenaline and noradrenaline. It acts as a neurotransmitter in the central nervous system but it is also produced peripherally and acts as a hormone.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0014046") -AnnotationAssertion(rdfs:label "dopamine secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - # Class: (glutamate secretion) AnnotationAssertion(Annotation( "GOC:ef") "The controlled release of glutamate by a cell. The glutamate is the most abundant excitatory neurotransmitter in the nervous system.") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0014047") AnnotationAssertion(rdfs:label "glutamate secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) -# Class: (regulation of glutamate secretion) - -AnnotationAssertion(Annotation( "GOC:ef") "Any process that modulates the frequency, rate or extent of the controlled release of glutamate.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0014048") -AnnotationAssertion(rdfs:label "regulation of glutamate secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of glutamate secretion) - -AnnotationAssertion(Annotation( "GOC:ef") "Any process that activates or increases the frequency, rate or extent of the controlled release of glutamate.") -AnnotationAssertion( "up regulation of glutamate secretion") -AnnotationAssertion( "up-regulation of glutamate secretion") -AnnotationAssertion( "upregulation of glutamate secretion") -AnnotationAssertion( "activation of glutamate secretion") -AnnotationAssertion( "stimulation of glutamate secretion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0014049") -AnnotationAssertion(rdfs:label "positive regulation of glutamate secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of glutamate secretion) - -AnnotationAssertion(Annotation( "GOC:ef") "Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of glutamate.") -AnnotationAssertion( "down regulation of glutamate secretion") -AnnotationAssertion( "down-regulation of glutamate secretion") -AnnotationAssertion( "downregulation of glutamate secretion") -AnnotationAssertion( "inhibition of glutamate secretion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0014050") -AnnotationAssertion(rdfs:label "negative regulation of glutamate secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (gamma-aminobutyric acid secretion) - -AnnotationAssertion(Annotation( "GOC:ef") "The regulated release of gamma-aminobutyric acid by a cell or a tissue. The gamma-aminobutyric acid is the principal inhibitory neurotransmitter in the brain but is also found in several extraneural tissues.") -AnnotationAssertion( "GABA secretion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0014051") -AnnotationAssertion(rdfs:label "gamma-aminobutyric acid secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of gamma-aminobutyric acid secretion) - -AnnotationAssertion(Annotation( "GOC:ef") "Any process that modulates the frequency, rate or extent of the regulated release of gamma-aminobutyric acid.") -AnnotationAssertion( "regulation of GABA secretion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0014052") -AnnotationAssertion(rdfs:label "regulation of gamma-aminobutyric acid secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of gamma-aminobutyric acid secretion) - -AnnotationAssertion(Annotation( "GOC:ef") "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of gamma-aminobutyric acid.") -AnnotationAssertion( "down regulation of gamma-aminobutyric acid secretion") -AnnotationAssertion( "down-regulation of gamma-aminobutyric acid secretion") -AnnotationAssertion( "downregulation of gamma-aminobutyric acid secretion") -AnnotationAssertion( "negative regulation of GABA secretion") -AnnotationAssertion( "inhibition of gamma-aminobutyric acid secretion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0014053") -AnnotationAssertion(rdfs:label "negative regulation of gamma-aminobutyric acid secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of gamma-aminobutyric acid secretion) - -AnnotationAssertion(Annotation( "GOC:ef") "Any process that activates or increases the frequency, rate or extent of the regulated release of gamma-aminobutyric acid.") -AnnotationAssertion( "positive regulation of GABA secretion") -AnnotationAssertion( "up regulation of gamma-aminobutyric acid secretion") -AnnotationAssertion( "up-regulation of gamma-aminobutyric acid secretion") -AnnotationAssertion( "upregulation of gamma-aminobutyric acid secretion") -AnnotationAssertion( "activation of gamma-aminobutyric acid secretion") -AnnotationAssertion( "stimulation of gamma-aminobutyric acid secretion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0014054") -AnnotationAssertion(rdfs:label "positive regulation of gamma-aminobutyric acid secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (acetylcholine secretion, neurotransmission) - -AnnotationAssertion(Annotation( "GOC:ef") "The regulated release of acetylcholine by a cell. The acetylcholine acts as a neurotransmitter that acts in both the peripheral nervous system (PNS) and central nervous system (CNS).") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0014055") -AnnotationAssertion(rdfs:label "acetylcholine secretion, neurotransmission") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of acetylcholine secretion, neurotransmission) - -AnnotationAssertion(Annotation( "GOC:ef") "Any process that modulates the frequency, rate or extent of the regulated release of acetylcholine.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0014056") -AnnotationAssertion(rdfs:label "regulation of acetylcholine secretion, neurotransmission") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of acetylcholine secretion, neurotransmission) - -AnnotationAssertion(Annotation( "GOC:ef") "Any process that activates or increases the frequency, rate or extent of the regulated release of acetylcholine.") -AnnotationAssertion( "up regulation of acetylcholine secretion") -AnnotationAssertion( "up-regulation of acetylcholine secretion") -AnnotationAssertion( "upregulation of acetylcholine secretion") -AnnotationAssertion( "activation of acetylcholine secretion") -AnnotationAssertion( "stimulation of acetylcholine secretion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0014057") -AnnotationAssertion(rdfs:label "positive regulation of acetylcholine secretion, neurotransmission") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (negative regulation of acetylcholine secretion, neurotransmission) - -AnnotationAssertion(Annotation( "GOC:ef") "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of acetylcholine.") -AnnotationAssertion( "down regulation of acetylcholine secretion") -AnnotationAssertion( "down-regulation of acetylcholine secretion") -AnnotationAssertion( "downregulation of acetylcholine secretion") -AnnotationAssertion( "inhibition of acetylcholine secretion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0014058") -AnnotationAssertion(rdfs:label "negative regulation of acetylcholine secretion, neurotransmission") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (regulation of dopamine secretion) - -AnnotationAssertion(Annotation( "GOC:ef") "Any process that modulates the frequency, rate or extent of the regulated release of dopamine.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0014059") -AnnotationAssertion(rdfs:label "regulation of dopamine secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of epinephrine secretion) - -AnnotationAssertion(Annotation( "GOC:ef") "Any process that modulates the frequency, rate or extent of the regulated release of epinephrine.") -AnnotationAssertion( "regulation of adrenaline secretion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0014060") -AnnotationAssertion(rdfs:label "regulation of epinephrine secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of norepinephrine secretion) - -AnnotationAssertion(Annotation( "GOC:ef") "Any process that modulates the frequency, rate or extent of the regulated release of norepinephrine.") -AnnotationAssertion( "regulation of noradrenaline secretion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0014061") -AnnotationAssertion(rdfs:label "regulation of norepinephrine secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of serotonin secretion) - -AnnotationAssertion(Annotation( "GOC:ef") "Any process that modulates the frequency, rate or extent of the regulated release of serotonin.") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:tb") "regulation of serotonin release") -AnnotationAssertion( "GO:0014062") -AnnotationAssertion(rdfs:label "regulation of serotonin secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of serotonin secretion) - -AnnotationAssertion(Annotation( "GOC:ef") "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of serotonin.") -AnnotationAssertion( "down regulation of serotonin secretion") -AnnotationAssertion( "down-regulation of serotonin secretion") -AnnotationAssertion( "downregulation of serotonin secretion") -AnnotationAssertion( "inhibition of serotonin secretion") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:tb") "positive regulation of serotonin release") -AnnotationAssertion( "GO:0014063") -AnnotationAssertion(rdfs:label "negative regulation of serotonin secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of serotonin secretion) - -AnnotationAssertion(Annotation( "GOC:ef") "Any process that activates or increases the frequency, rate or extent of the regulated release of serotonin.") -AnnotationAssertion( "up regulation of serotonin secretion") -AnnotationAssertion( "up-regulation of serotonin secretion") -AnnotationAssertion( "upregulation of serotonin secretion") -AnnotationAssertion( "activation of serotonin secretion") -AnnotationAssertion( "stimulation of serotonin secretion") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:tb") "positive regulation of serotonin release") -AnnotationAssertion( "GO:0014064") -AnnotationAssertion(rdfs:label "positive regulation of serotonin secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (response to organic cyclic compound) - -AnnotationAssertion(Annotation( "GOC:ef") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus.") -AnnotationAssertion(Annotation( "GOC:mah") "response to organic cyclic substance") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0014070") -AnnotationAssertion(rdfs:label "response to organic cyclic compound") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (response to purine-containing compound) - -AnnotationAssertion(Annotation( "GOC:ef") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a purine-containing compound stimulus.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "response to purine") -AnnotationAssertion( "GO:0014074") -AnnotationAssertion(rdfs:label "response to purine-containing compound") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (response to amine) - -AnnotationAssertion(Annotation( "GOC:ef") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amine stimulus. An amine is a compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups.") -AnnotationAssertion(Annotation( "GOC:dos") "response to amine stimulus") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0014075") -AnnotationAssertion(rdfs:label "response to amine") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (striated muscle tissue development) - -AnnotationAssertion(Annotation( "CL:0000737") Annotation( "GOC:dph") Annotation( "GOC:mtg_muscle") "The process whose specific outcome is the progression of a striated muscle over time, from its formation to the mature structure. Striated muscle contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle. Skeletal muscle myoblasts fuse to form myotubes and eventually multinucleated muscle fibers. The fusion of cardiac cells is very rare and can only form binucleate cells.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0014706") -AnnotationAssertion(rdfs:label "striated muscle tissue development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (branchiomeric skeletal muscle development) - -AnnotationAssertion(Annotation( "GOC:mtg_muscle") "The process whose specific outcome is the progression of the branchiomeric skeletal muscle over time, from its formation to the mature structure. The branchiomeric muscle is derived from cranial mesoderm and controls facial expression, pharyngeal and laryngeal function, operating the jaw. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle. Branchiomeric muscles of mammals correspond to the gill musculature of fish.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0014707") -AnnotationAssertion(rdfs:label "branchiomeric skeletal muscle development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of somitomeric trunk muscle development) - -AnnotationAssertion(Annotation( "GOC:mtg_muscle") "Any process that modulates the frequency, rate or extent of somitomeric trunk muscle development.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0014708") -AnnotationAssertion(rdfs:label "regulation of somitomeric trunk muscle development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of somitomeric trunk muscle development) - -AnnotationAssertion(Annotation( "GOC:mtg_muscle") "Any process that activates, maintains or increases the frequency, rate or extent of somitomeric trunk muscle development. The somitomeric trunk muscle is derived from somitomeric mesoderm. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0014709") -AnnotationAssertion(rdfs:label "positive regulation of somitomeric trunk muscle development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of somitomeric trunk muscle development) - -AnnotationAssertion(Annotation( "GOC:mtg_muscle") "Any process that stops, prevents, or reduces the frequency, rate or extent of somitomeric trunk muscle development. The somitomeric trunk muscle is derived from somitomeric mesoderm. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0014710") -AnnotationAssertion(rdfs:label "negative regulation of somitomeric trunk muscle development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of branchiomeric skeletal muscle development) - -AnnotationAssertion(Annotation( "GOC:mtg_muscle") "Any process that modulates the frequency, rate or extent of branchiomeric skeletal muscle development. Branchiomeric skeletal muscle development is the process whose specific outcome is the progression of the branchiomeric skeletal muscle over time, from its formation to the mature structure.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0014711") -AnnotationAssertion(rdfs:label "regulation of branchiomeric skeletal muscle development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of branchiomeric skeletal muscle development) - -AnnotationAssertion(Annotation( "GOC:mtg_muscle") "Any process that activates, maintains or increases the frequency, rate or extent of branchiomeric skeletal muscle development. Branchiomeric skeletal muscle development is the process whose specific outcome is the progression of the branchiomeric skeletal muscle over time, from its formation to the mature structure.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0014712") -AnnotationAssertion(rdfs:label "positive regulation of branchiomeric skeletal muscle development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of branchiomeric skeletal muscle development) - -AnnotationAssertion(Annotation( "GOC:mtg_muscle") "Any process that stops, prevents, or reduces the frequency, rate or extent of branchiomeric skeletal muscle development. Branchiomeric skeletal muscle development is the process whose specific outcome is the progression of the branchiomeric skeletal muscle over time, from its formation to the mature structure.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0014713") -AnnotationAssertion(rdfs:label "negative regulation of branchiomeric skeletal muscle development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of extraocular skeletal muscle development) - -AnnotationAssertion(Annotation( "GOC:mtg_muscle") "Any process that modulates the frequency, rate or extent of extraocular skeletal muscle development. Extraocular skeletal muscle development is the process whose specific outcome is the progression of the extraocular skeletal muscle over time, from its formation to the mature structure. The extraocular muscle is derived from cranial mesoderm and controls eye movements. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0014725") -AnnotationAssertion(rdfs:label "regulation of extraocular skeletal muscle development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of extraocular skeletal muscle development) - -AnnotationAssertion(Annotation( "GOC:mtg_muscle") "Any process that stops, prevents, or reduces the frequency, rate or extent of extraocular skeletal muscle development. Extraocular skeletal muscle development is the process whose specific outcome is the progression of the extraocular skeletal muscle over time, from its formation to the mature structure. The extraocular muscle is derived from cranial mesoderm and controls eye movements. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0014726") -AnnotationAssertion(rdfs:label "negative regulation of extraocular skeletal muscle development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of extraocular skeletal muscle development) - -AnnotationAssertion(Annotation( "GOC:mtg_muscle") "Any process that activates, maintains or increases the frequency, rate or extent of extraocular skeletal muscle development. Extraocular skeletal muscle development is the process whose specific outcome is the progression of the extraocular skeletal muscle over time, from its formation to the mature structure. The extraocular muscle is derived from cranial mesoderm and controls eye movements. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0014727") -AnnotationAssertion(rdfs:label "positive regulation of extraocular skeletal muscle development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of skeletal muscle adaptation) - -AnnotationAssertion(Annotation( "GOC:mtg_muscle") "Any process in which skeletal muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "regulation of skeletal muscle plasticity") -AnnotationAssertion( "GO:0014733") -AnnotationAssertion(rdfs:label "regulation of skeletal muscle adaptation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (skeletal muscle hypertrophy) - -AnnotationAssertion(Annotation( "GOC:mtg_muscle") "The enlargement or overgrowth of all or part of an organ due to an increase in size (not length) of individual muscle fibers without cell division. In the case of skeletal muscle cells this happens due to the additional synthesis of sarcomeric proteins and assembly of myofibrils.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0014734") -AnnotationAssertion(rdfs:label "skeletal muscle hypertrophy") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of muscle hypertrophy) - -AnnotationAssertion(Annotation( "GOC:mtg_muscle") "Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle hypertrophy.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0014741") -AnnotationAssertion(rdfs:label "negative regulation of muscle hypertrophy") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of muscle hypertrophy) - -AnnotationAssertion(Annotation( "GOC:mtg_muscle") "Any process that activates or increases the frequency, rate or extent of muscle hypertrophy.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0014742") -AnnotationAssertion(rdfs:label "positive regulation of muscle hypertrophy") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of muscle hypertrophy) - -AnnotationAssertion(Annotation( "GOC:mtg_muscle") "Any process that modulates the frequency, rate or extent of muscle hypertrophy.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0014743") -AnnotationAssertion(rdfs:label "regulation of muscle hypertrophy") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of muscle adaptation) - -AnnotationAssertion(Annotation( "GOC:mtg_muscle") "Any process that activates or increases the frequency, rate or extent of muscle adaptation.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "positive regulation of muscle plasticity") -AnnotationAssertion( "GO:0014744") -AnnotationAssertion(rdfs:label "positive regulation of muscle adaptation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (negative regulation of muscle adaptation) - -AnnotationAssertion(Annotation( "GOC:mtg_muscle") "Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle adaptation.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "negative regulation of muscle plasticity") -AnnotationAssertion( "GO:0014745") -AnnotationAssertion(rdfs:label "negative regulation of muscle adaptation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (smooth muscle adaptation) - -AnnotationAssertion(Annotation( "GOC:mtg_muscle") "Any process in which smooth muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "smooth muscle plasticity") -AnnotationAssertion( "GO:0014805") -AnnotationAssertion(rdfs:label "smooth muscle adaptation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of somitogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_muscle") "Any process that modulates the frequency, rate or extent of somitogenesis.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0014807") -AnnotationAssertion(rdfs:label "regulation of somitogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (muscle cell migration) - -AnnotationAssertion(Annotation( "CL:0000187") Annotation( "GOC:mtg_muscle") "The orderly movement of a muscle cell from one site to another, often during the development of a multicellular organism.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0014812") -AnnotationAssertion(rdfs:label "muscle cell migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of skeletal muscle contraction) - -AnnotationAssertion(Annotation( "GOC:ef") Annotation( "GOC:mtg_muscle") "Any process that modulates the frequency, rate or extent of skeletal muscle contraction.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0014819") -AnnotationAssertion(rdfs:label "regulation of skeletal muscle contraction") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (phasic smooth muscle contraction) AnnotationAssertion(Annotation( "GOC:mtg_muscle") "A process in which force is generated within phasic smooth muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. In the phasic smooth muscle, the muscle contraction occurs without an ordered sarcomeric structure. Phasic smooth muscle contraction occurs in a series of discrete contractions and relaxations.") @@ -63590,309 +23057,6 @@ AnnotationAssertion( "phasic smooth muscle contraction") SubClassOf( ) -# Class: (intestine smooth muscle contraction) - -AnnotationAssertion(Annotation( "GOC:mtg_muscle") Annotation( "MA:0001539") Annotation( "MSH:D007422") "A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the intestine. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The intestine is the section of the alimentary canal from the stomach to the anal canal. It includes the large intestine and small intestine.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0014827") -AnnotationAssertion(rdfs:label "intestine smooth muscle contraction") -SubClassOf( ) -SubClassOf( ) - -# Class: (gastro-intestinal system smooth muscle contraction) - -AnnotationAssertion(Annotation( "GOC:mtg_muscle") Annotation( "MA:0001523") Annotation( "MSH:D041981") "A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the gastro-intestinal system. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The gastro-intestinal system generally refers to the digestive structures stretching from the mouth to anus, but does not include the accessory glandular organs (liver, pancreas and biliary tract).") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0014831") -AnnotationAssertion(rdfs:label "gastro-intestinal system smooth muscle contraction") -SubClassOf( ) - -# Class: (urinary bladder smooth muscle contraction) - -AnnotationAssertion(Annotation( "GOC:mr") Annotation( "GOC:mtg_muscle") Annotation( "PMID:11768524") Annotation( "PMID:18276178") Annotation( "PMID:538956") "A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the urinary bladder. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The urinary bladder is a musculomembranous sac along the urinary tract.") -AnnotationAssertion( ) -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0014832") -AnnotationAssertion(rdfs:label "urinary bladder smooth muscle contraction") -SubClassOf( ) -SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) -DisjointClasses( ObjectSomeValuesFrom( )) - -# Class: (myoblast differentiation involved in skeletal muscle regeneration) - -AnnotationAssertion(Annotation( "CL:0000056") Annotation( "GOC:ef") Annotation( "GOC:mtg_muscle") Annotation( "PMID:16607119") "The process in which a relatively unspecialized satellite cell acquires specialized features of a myoblast. This occurs as part of skeletal muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0014835") -AnnotationAssertion(rdfs:label "myoblast differentiation involved in skeletal muscle regeneration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (myoblast migration involved in skeletal muscle regeneration) - -AnnotationAssertion(Annotation( "CL:0000056") Annotation( "GOC:ef") Annotation( "GOC:mtg_muscle") Annotation( "PMID:16607119") "The process in which a myoblast migrates along an entire fiber to the site of injury. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.") -AnnotationAssertion( "mononucleate cell migration involved in skeletal muscle regeneration") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0014839") -AnnotationAssertion(rdfs:label "myoblast migration involved in skeletal muscle regeneration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (urinary tract smooth muscle contraction) - -AnnotationAssertion(Annotation( "GOC:ef") Annotation( "GOC:mtg_muscle") Annotation( "MA:0000325") Annotation( "MSH:D014551") "A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the urinary tract. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The urinary tract consists of organs of the body that produce and discharge urine. These include the kidneys, ureters, bladder, and urethra.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0014848") -AnnotationAssertion(rdfs:label "urinary tract smooth muscle contraction") -SubClassOf( ) - -# Class: (ureter smooth muscle contraction) - -AnnotationAssertion(Annotation( "GOC:mtg_muscle") Annotation( "MA:0000378") "A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the ureter. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The ureter is one of a pair of thick-walled tubes that transports urine from the kidney pelvis to the urinary bladder.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0014849") -AnnotationAssertion(rdfs:label "ureter smooth muscle contraction") -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of skeletal muscle contraction by neural stimulation via neuromuscular junction) - -AnnotationAssertion(Annotation( "GOC:ef") Annotation( "GOC:mtg_muscle") "Any process that modulates the frequency, rate or extent of skeletal muscle contraction by variation of the pattern of stimulation by nervous system.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0014852") -AnnotationAssertion(rdfs:label "regulation of skeletal muscle contraction by neural stimulation via neuromuscular junction") -SubClassOf( ) - -# Class: (regulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction) - -AnnotationAssertion(Annotation( "GOC:ef") Annotation( "GOC:mtg_muscle") "Any process, involved in skeletal muscle contraction, that modulates the establishment or extent of the excitatory postsynaptic potential (EPSP). Excitatory postsynaptic potential (EPSP) is a temporay increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential.") -AnnotationAssertion( "regulation of excitatory post-synaptic membrane potential involved in skeletal muscle contraction") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0014853") -AnnotationAssertion(rdfs:label "regulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (striated muscle cell proliferation) - -AnnotationAssertion(Annotation( "CL:0000737") Annotation( "GOC:ef") Annotation( "GOC:mtg_muscle") "The multiplication or reproduction of striated muscle cells, resulting in the expansion of a cell population. Striated muscles contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0014855") -AnnotationAssertion(rdfs:label "striated muscle cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (skeletal muscle cell proliferation) - -AnnotationAssertion(Annotation( "CL:0000188") Annotation( "GOC:ef") Annotation( "GOC:mtg_muscle") "The multiplication or reproduction of skeletal muscle cells, resulting in the expansion of a cell population.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0014856") -AnnotationAssertion(rdfs:label "skeletal muscle cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of skeletal muscle cell proliferation) - -AnnotationAssertion(Annotation( "CL:0000188") Annotation( "GOC:ef") Annotation( "GOC:mtg_muscle") "Any process that modulates the frequency, rate or extent of skeletal muscle cell proliferation.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0014857") -AnnotationAssertion(rdfs:label "regulation of skeletal muscle cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of skeletal muscle cell proliferation) - -AnnotationAssertion(Annotation( "CL:0000188") Annotation( "GOC:ef") Annotation( "GOC:mtg_muscle") "Any process that activates or increases the frequency, rate or extent of skeletal muscle cell proliferation.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0014858") -AnnotationAssertion(rdfs:label "positive regulation of skeletal muscle cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of skeletal muscle cell proliferation) - -AnnotationAssertion(Annotation( "CL:0000188") Annotation( "GOC:ef") Annotation( "GOC:mtg_muscle") "Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle cell proliferation.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0014859") -AnnotationAssertion(rdfs:label "negative regulation of skeletal muscle cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (neurotransmitter secretion involved in regulation of skeletal muscle contraction) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_muscle") Annotation( "GOC:tb") "The regulated release of neurotransmitter into the synaptic cleft involved in skeletal muscle contraction. A neurotransmitter is any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell. Among the many substances that have the properties of a neurotransmitter are acetylcholine, noradrenaline, adrenaline, dopamine, glycine, gamma aminobutyrate, glutamic acid, substance P, enkephalins, endorphins and serotonin.") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "neurotransmitter secretion involved in control of skeletal muscle contraction") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0014860") -AnnotationAssertion(rdfs:label "neurotransmitter secretion involved in regulation of skeletal muscle contraction") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (regulation of skeletal muscle contraction via regulation of action potential) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mtg_cardiac_conduct_nov11") Annotation( "GOC:mtg_muscle") "Any process that modulates the frequency, rate or extent of skeletal muscle contraction by depolarization of muscle membrane and ionic fluxes.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "regulation of skeletal muscle contraction via membrane action potential") -AnnotationAssertion( "GO:0014861") -AnnotationAssertion(rdfs:label "regulation of skeletal muscle contraction via regulation of action potential") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (skeletal myofibril assembly) - -AnnotationAssertion(Annotation( "GOC:ef") Annotation( "GOC:mtg_muscle") "The process whose specific outcome is the progression of the skeletal myofibril over time, from its formation to the mature structure. A skeletal myofibril is a myofibril specific to skeletal muscle cells.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0014866") -AnnotationAssertion(rdfs:label "skeletal myofibril assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (myoblast division) - -AnnotationAssertion(Annotation( "CL:0000056") Annotation( "GOC:ef") Annotation( "GOC:mtg_muscle") "The process resulting in the physical partitioning and separation of a myoblast into daughter cells. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0014872") -AnnotationAssertion(rdfs:label "myoblast division") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (response to stimulus involved in regulation of muscle adaptation) - -AnnotationAssertion(Annotation( "GOC:ef") Annotation( "GOC:mtg_muscle") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. This occurs as part of the regulation of muscle adaptation.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "response to stimulus involved in regulation of muscle plasticity") -AnnotationAssertion( "GO:0014874") -AnnotationAssertion(rdfs:label "response to stimulus involved in regulation of muscle adaptation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (response to electrical stimulus involved in regulation of muscle adaptation) - -AnnotationAssertion(Annotation( "GOC:ef") Annotation( "GOC:mtg_muscle") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electrical stimulus. This process occurs as part of the regulation of muscle adaptation.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "response to electrical stimulus involved in regulation of muscle plasticity") -AnnotationAssertion( "GO:0014878") -AnnotationAssertion(rdfs:label "response to electrical stimulus involved in regulation of muscle adaptation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (detection of electrical stimulus involved in regulation of muscle adaptation) - -AnnotationAssertion(Annotation( "GOC:ef") Annotation( "GOC:mtg_muscle") "The series of events by which an electrical stimulus is received and converted into a molecular signal. This occurs as part of the regulation of muscle adaptation.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0014879") -AnnotationAssertion(rdfs:label "detection of electrical stimulus involved in regulation of muscle adaptation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cardiac muscle adaptation) - -AnnotationAssertion(Annotation( "GOC:mtg_muscle") "The process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "cardiac muscle plasticity") -AnnotationAssertion( "GO:0014887") -AnnotationAssertion(rdfs:label "cardiac muscle adaptation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (striated muscle adaptation) - -AnnotationAssertion(Annotation( "GOC:mtg_muscle") "Any process in which striated muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "striated muscle plasticity") -AnnotationAssertion( "GO:0014888") -AnnotationAssertion(rdfs:label "striated muscle adaptation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (smooth muscle hypertrophy) - -AnnotationAssertion(Annotation( "GOC:mtg_muscle") "The enlargement or overgrowth of all or part of an organ due to an increase in size of its smooth muscle cells without cell division. Physiological hypertrophy is a normal process during development, and can also occur in mature structures on demand. In the uterus, smooth muscle cells undergo hypertrophy during pregnancy.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0014895") -AnnotationAssertion(rdfs:label "smooth muscle hypertrophy") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (muscle hypertrophy) - -AnnotationAssertion(Annotation( "GOC:mtg_muscle") "The muscle system process that results in enlargement or overgrowth of all or part of a muscle organ due to an increase in the size of its muscle cells. Physiological hypertrophy is a normal process during development (it stops in cardiac muscle after adolescence) and can also be brought on in response to demand. In athletes cardiac and skeletal muscles undergo hypertrophy stimulated by increasing muscle activity on exercise. Smooth muscle cells in the uterus undergo hypertrophy during pregnancy.") -AnnotationAssertion( "Wikipedia:Muscle_hypertrophy") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0014896") -AnnotationAssertion(rdfs:label "muscle hypertrophy") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (striated muscle hypertrophy) - -AnnotationAssertion(Annotation( "GOC:mtg_muscle") "The enlargement or overgrowth of all or part of an organ due to an increase in size of muscle cells without cell division. In the case of striated muscle, this happens due to the additional synthesis of sarcomeric proteins and assembly of myofibrils.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0014897") -AnnotationAssertion(rdfs:label "striated muscle hypertrophy") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (myotube differentiation) - -AnnotationAssertion(Annotation( "GOC:mtg_muscle") "The process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotube differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual myotubes can fuse to form bigger myotubes and start to contract. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0014902") -AnnotationAssertion(rdfs:label "myotube differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (myotube cell development) - -AnnotationAssertion(Annotation( "GOC:mtg_muscle") "The process aimed at the progression of a myotube cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0014904") -AnnotationAssertion(rdfs:label "myotube cell development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (myotube cell development involved in skeletal muscle regeneration) - -AnnotationAssertion(Annotation( "GOC:mtg_muscle") "The process aimed at the progression of a myotube cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. This occurs as part of the process of skeletal muscle regeneration. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0014906") -AnnotationAssertion(rdfs:label "myotube cell development involved in skeletal muscle regeneration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (myotube differentiation involved in skeletal muscle regeneration) - -AnnotationAssertion(Annotation( "GOC:mtg_muscle") "The process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotube differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual myotubes can fuse to form bigger myotubes and start to contract. This process occurs as part of the process of skeletal muscle regeneration. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0014908") -AnnotationAssertion(rdfs:label "myotube differentiation involved in skeletal muscle regeneration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (smooth muscle cell migration) - -AnnotationAssertion(Annotation( "CL:0000192") Annotation( "GOC:mtg_muscle") "The orderly movement of a smooth muscle cell from one site to another, often during the development of a multicellular organism.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0014909") -AnnotationAssertion(rdfs:label "smooth muscle cell migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of smooth muscle cell migration) - -AnnotationAssertion(Annotation( "CL:0000192") Annotation( "GOC:mtg_muscle") "Any process that modulates the frequency, rate or extent of smooth muscle cell migration.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0014910") -AnnotationAssertion(rdfs:label "regulation of smooth muscle cell migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of smooth muscle cell migration) - -AnnotationAssertion(Annotation( "CL:0000192") Annotation( "GOC:mtg_muscle") "Any process that activates, maintains or increases the frequency, rate or extent of smooth muscle cell migration.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0014911") -AnnotationAssertion(rdfs:label "positive regulation of smooth muscle cell migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of smooth muscle cell migration) - -AnnotationAssertion(Annotation( "CL:0000192") Annotation( "GOC:mtg_muscle") "Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle cell migration.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0014912") -AnnotationAssertion(rdfs:label "negative regulation of smooth muscle cell migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (protein transport) AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") @@ -63904,77 +23068,10 @@ AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "protein transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ) -# Class: (monoatomic ion transmembrane transporter activity) - -AnnotationAssertion(Annotation( "GOC:dgf") Annotation( "GOC:mtg_transport") Annotation( "ISBN:0815340729") "Enables the transfer of an ion from one side of a membrane to the other.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/24479"^^xsd:anyURI) -AnnotationAssertion( "ion transmembrane transporter activity") -AnnotationAssertion( "ion transporter activity") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0015075") -AnnotationAssertion(rdfs:label "monoatomic ion transmembrane transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "GO_REF:0000090") ObjectSomeValuesFrom( )) - -# Class: (sodium ion transmembrane transporter activity) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:ai") Annotation( "RHEA:34963") "Enables the transfer of sodium ions (Na+) from one side of a membrane to the other.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/24076"^^xsd:anyURI) -AnnotationAssertion( "GO:0022816") -AnnotationAssertion( "RHEA:34963") -AnnotationAssertion( "sodium transporter activity") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0015081") -AnnotationAssertion(rdfs:label "sodium ion transmembrane transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (calcium ion transmembrane transporter activity) - -AnnotationAssertion(Annotation( "GOC:dgf") Annotation( "RHEA:29671") "Enables the transfer of calcium (Ca) ions from one side of a membrane to the other.") -AnnotationAssertion( "RHEA:29671") -AnnotationAssertion(Annotation(rdfs:label "CatSper Channel Mediated Calcium Transport") "Reactome:R-HSA-2534359") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0015085") -AnnotationAssertion(rdfs:label "calcium ion transmembrane transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (organic cation transmembrane transporter activity) - -AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:mtg_transport") Annotation( "ISBN:0815340729") "Enables the transfer of organic cations from one side of a membrane to the other. Organic cations are atoms or small molecules with a positive charge that contain carbon in covalent linkage.") -AnnotationAssertion(Annotation(rdfs:label "abacavir [extracellular] => abacavir [cytosol]") "Reactome:R-HSA-2161500") -AnnotationAssertion(Annotation(rdfs:label "OCT1 transports organic cations into hepatic cells") "Reactome:R-HSA-549129") -AnnotationAssertion(Annotation(rdfs:label "OCT2 mediates tubular uptake of organic cations in the kidney") "Reactome:R-HSA-549279") -AnnotationAssertion(Annotation(rdfs:label "OCT3 mediates renal clearance of organic cations") "Reactome:R-HSA-549304") -AnnotationAssertion(Annotation(rdfs:label "OCT1 transports organic cations out of hepatic cells") "Reactome:R-HSA-549322") -AnnotationAssertion(Annotation(rdfs:label "OCT2 mediates tubular secretion of organic cations in the kidney") "Reactome:R-HSA-561054") -AnnotationAssertion(Annotation(rdfs:label "OCT3 mediates renal uptake of organic cations") "Reactome:R-HSA-561072") -AnnotationAssertion(Annotation(rdfs:label "SLCO1A2 transports Cipro(1+) into the cytosol") "Reactome:R-HSA-9794270") -AnnotationAssertion(Annotation(rdfs:label "SLC22A1 transports Cipro into renal cell") "Reactome:R-HSA-9794523") -AnnotationAssertion(Annotation(rdfs:label "SLC22A1 transports Cipro into hepatic cell") "Reactome:R-HSA-9795207") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0015101") -AnnotationAssertion(rdfs:label "organic cation transmembrane transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (inorganic anion transmembrane transporter activity) - -AnnotationAssertion(Annotation( "GOC:ai") "Enables the transfer of inorganic anions from one side of a membrane to the other. Inorganic anions are atoms or small molecules with a negative charge which do not contain carbon in covalent linkage.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0015103") -AnnotationAssertion(rdfs:label "inorganic anion transmembrane transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (bicarbonate transmembrane transporter activity) AnnotationAssertion(Annotation( "GOC:ai") "Enables the transfer of bicarbonate from one side of a membrane to the other. Bicarbonate is the hydrogencarbonate ion, HCO3-.") @@ -63983,384 +23080,9 @@ AnnotationAssertion(Annotation(rdfs:label "BESTs transport cytosolic HCO3- to ex AnnotationAssertion( "molecular_function") AnnotationAssertion( "GO:0015106") AnnotationAssertion(rdfs:label "bicarbonate transmembrane transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (phosphate ion transmembrane transporter activity) - -AnnotationAssertion(Annotation( "GOC:ai") "Enables the transfer of phosphate (PO4 3-) ions from one side of a membrane to the other.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2012-11-22T15:43:10Z") -AnnotationAssertion( "GO:1901677") -AnnotationAssertion( "RHEA:32823") -AnnotationAssertion( "molecular_function") -AnnotationAssertion(Annotation( "GOC:vw") "phosphate transmembrane transporter activity") -AnnotationAssertion( "GO:0015114") -AnnotationAssertion(rdfs:label "phosphate ion transmembrane transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "GO_REF:0000090") ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (sulfate transmembrane transporter activity) - -AnnotationAssertion(Annotation( "GOC:ai") "Enables the transfer of sulfate ions, SO4(2-), from one side of a membrane to the other.") -AnnotationAssertion( "RHEA:34983") -AnnotationAssertion(Annotation(rdfs:label "Defective SLC26A2 does not cotransport extracellular SO4(2-), H+ to cytosol") "Reactome:R-HSA-3560789") -AnnotationAssertion(Annotation(rdfs:label "SLC26A1,2 cotransport SO4(2-), H+ from extracellular region to cytosol") "Reactome:R-HSA-427555") -AnnotationAssertion(Annotation(rdfs:label "SLC26A11 transports SO4(2-) from extracellular region to cytosol") "Reactome:R-HSA-8875871") -AnnotationAssertion( "sulphate transporter activity") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "sulfate permease activity") -AnnotationAssertion( "GO:0015116") -AnnotationAssertion(rdfs:label "sulfate transmembrane transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "GO_REF:0000090") ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (acetate transmembrane transporter activity) - -AnnotationAssertion(Annotation( "GOC:ai") "Enables the transfer of acetate from one side of a membrane to the other. Acetate is the 2-carbon carboxylic acid ethanoic acid.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0015123") -AnnotationAssertion(rdfs:label "acetate transmembrane transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "GO_REF:0000090") ObjectSomeValuesFrom( )) - -# Class: (bile acid transmembrane transporter activity) - -AnnotationAssertion(Annotation( "GOC:ai") "Enables the transfer of bile acid from one side of a membrane to the other. Bile acids are any of a group of steroid carboxylic acids occurring in bile, where they are present as the sodium salts of their amides with glycine or taurine.") -AnnotationAssertion(Annotation(rdfs:label "SLCO1B3 transports ALB:(GCCA, TCCA) from extracellular region to cytosol") "Reactome:R-HSA-194079") -AnnotationAssertion(Annotation(rdfs:label "SLCO1B1 transports ALB:(GCCA,TCCA) from extracellular region to cytosol") "Reactome:R-HSA-194083") -AnnotationAssertion(Annotation(rdfs:label "Transport (influx) of bile salts and acids by OATP-A") "Reactome:R-HSA-194130") -AnnotationAssertion(Annotation(rdfs:label "Defective SLCO1B1 does not transport BIL from extracellular region (blood) to cytosol (hepatocyte)") "Reactome:R-HSA-5661184") -AnnotationAssertion(Annotation(rdfs:label "Defective SLCO1B3 does not transport BIL from extracellular region (blood) to cytosol (hepatocyte)") "Reactome:R-HSA-5661198") -AnnotationAssertion(Annotation(rdfs:label "SLC51A:SLC51B transports bile salts from cytosol to extracellular region") "Reactome:R-HSA-9733964") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0015125") -AnnotationAssertion(rdfs:label "bile acid transmembrane transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (bilirubin transmembrane transporter activity) - -AnnotationAssertion(Annotation( "GOC:ai") Annotation( "ISBN:0198547684") "Enables the transfer of bilirubin from one side of a membrane to the other. Bilirubin is a linear tetrapyrrole produced in the reticuloendothelial system from biliverdin and transported to the liver as a complex with serum albumin. In the liver, bilirubin is converted to bilirubin bisglucuronide, which is excreted in the bile.") -AnnotationAssertion(Annotation(rdfs:label "Defective ABCC2 does not transport BMG,BDG from cytosol to extracellular region") "Reactome:R-HSA-5679031") -AnnotationAssertion(Annotation(rdfs:label "ABCC2 transports BMG,BDG from cytosol to extracellular region") "Reactome:R-HSA-5679041") -AnnotationAssertion(Annotation(rdfs:label "ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region") "Reactome:R-HSA-9661417") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0015127") -AnnotationAssertion(rdfs:label "bilirubin transmembrane transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (carbohydrate transmembrane transporter activity) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "GOC:mtg_transport") Annotation( "ISBN:0815340729") "Enables the transfer of carbohydrate from one side of a membrane to the other.") -AnnotationAssertion( "GO:1901476") -AnnotationAssertion( "sugar transporter") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "carbohydrate transporter activity") -AnnotationAssertion( "GO:0015144") -AnnotationAssertion(rdfs:label "carbohydrate transmembrane transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "GO_REF:0000090") ObjectSomeValuesFrom( )) - -# Class: (monosaccharide transmembrane transporter activity) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "GOC:mtg_transport") Annotation( "ISBN:0815340729") "Enables the transfer of a monosaccharide from one side of a membrane to the other.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0015145") -AnnotationAssertion(rdfs:label "monosaccharide transmembrane transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (pentose transmembrane transporter activity) - -AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:mtg_transport") Annotation( "ISBN:0815340729") "Enables the transfer of a pentose sugar from one side of a membrane to the other. Pentose is a monosaccharide with 5 carbon atoms.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0015146") -AnnotationAssertion(rdfs:label "pentose transmembrane transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (hexose transmembrane transporter activity) - -AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:mtg_transport") Annotation( "ISBN:0815340729") "Enables the transfer of a hexose sugar, a monosaccharide with 6 carbon atoms, from one side of a membrane to the other.") -AnnotationAssertion(Annotation(rdfs:label "SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region") "Reactome:R-HSA-189242") -AnnotationAssertion(Annotation(rdfs:label "Defective SLC2A2 does not transport Fru, Gal, Glc from cytosol to extracellular region") "Reactome:R-HSA-5638222") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0015149") -AnnotationAssertion(rdfs:label "hexose transmembrane transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "GO_REF:0000090") ObjectSomeValuesFrom( )) - -# Class: (polysaccharide transmembrane transporter activity) - -AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:mtg_transport") Annotation( "ISBN:0815340729") "Enables the transfer of polysaccharides from one side of a membrane to the other. A polysaccharide is a polymer of many (typically more than 10) monosaccharide residues linked glycosidically.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0015159") -AnnotationAssertion(rdfs:label "polysaccharide transmembrane transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (amino acid transmembrane transporter activity) - -AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:mtg_transport") Annotation( "ISBN:0815340729") "Enables the transfer of amino acids from one side of a membrane to the other. Amino acids are organic molecules that contain an amino group and a carboxyl group.") -AnnotationAssertion( "GO:0015359") -AnnotationAssertion( "amino acid transporter activity") -AnnotationAssertion(Annotation(rdfs:label "glutamate uptake by astrocytes") "Reactome:R-HSA-210439") -AnnotationAssertion(Annotation(rdfs:label "L-Glutamine transport into neurons") "Reactome:R-HSA-212642") -AnnotationAssertion(Annotation(rdfs:label "SLC6A18 transports Gly from extracellular region to cytosol") "Reactome:R-HSA-351963") -AnnotationAssertion(Annotation(rdfs:label "SLC6A6-mediated uptake of taurine and beta-alanine") "Reactome:R-HSA-351987") -AnnotationAssertion(Annotation(rdfs:label "SLC6A12 (BGT-1)-mediated uptake of GABA and betaine") "Reactome:R-HSA-352029") -AnnotationAssertion(Annotation(rdfs:label "SLC6A20 cotransports L-Pro, Na+ from the extracellular region to cytosol") "Reactome:R-HSA-352052") -AnnotationAssertion(Annotation(rdfs:label "SLC6A15-mediated amino acid uptake") "Reactome:R-HSA-352059") -AnnotationAssertion(Annotation(rdfs:label "SLC43A1 (LAT3)-mediated uptake of large neutral amino acids") "Reactome:R-HSA-352103") -AnnotationAssertion(Annotation(rdfs:label "SLC43A2 (LAT4)-mediated uptake of large neutral amino acids") "Reactome:R-HSA-352107") -AnnotationAssertion(Annotation(rdfs:label "SLC38A2 (ATA2)-mediated uptake of neutral amino acids") "Reactome:R-HSA-352108") -AnnotationAssertion(Annotation(rdfs:label "SLC38A1 (ATA1)-mediated uptake of neutral amino acids") "Reactome:R-HSA-352119") -AnnotationAssertion(Annotation(rdfs:label "SLC38A4 (ATA3)-mediated uptake of arginine and lysine") "Reactome:R-HSA-352136") -AnnotationAssertion(Annotation(rdfs:label "SLC16A10-mediated uptake of aromatic amino acids") "Reactome:R-HSA-352158") -AnnotationAssertion(Annotation(rdfs:label "SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine") "Reactome:R-HSA-352174") -AnnotationAssertion(Annotation(rdfs:label "SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine") "Reactome:R-HSA-352182") -AnnotationAssertion(Annotation(rdfs:label "SLC7A8-mediated uptake of neutral amino acids") "Reactome:R-HSA-352191") -AnnotationAssertion(Annotation(rdfs:label "SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol") "Reactome:R-HSA-352232") -AnnotationAssertion(Annotation(rdfs:label "SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine") "Reactome:R-HSA-352347") -AnnotationAssertion(Annotation(rdfs:label "SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine") "Reactome:R-HSA-352354") -AnnotationAssertion(Annotation(rdfs:label "SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine") "Reactome:R-HSA-352364") -AnnotationAssertion(Annotation(rdfs:label "SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine") "Reactome:R-HSA-352371") -AnnotationAssertion(Annotation(rdfs:label "SLC1A5-mediated exchange of alanine and glutamine across the plasma membrane") "Reactome:R-HSA-352379") -AnnotationAssertion(Annotation(rdfs:label "SLC1A5-mediated exchange of glutamine and alanine across the plasma membrane") "Reactome:R-HSA-352385") -AnnotationAssertion(Annotation(rdfs:label "SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol") "Reactome:R-HSA-375405") -AnnotationAssertion(Annotation(rdfs:label "SLC36A1-mediated uptake of glycine, proline, and alanine") "Reactome:R-HSA-375417") -AnnotationAssertion(Annotation(rdfs:label "SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol") "Reactome:R-HSA-375473") -AnnotationAssertion(Annotation(rdfs:label "SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol") "Reactome:R-HSA-375487") -AnnotationAssertion(Annotation(rdfs:label "SLC7A2, isoform B (CAT-2B)-mediated uptake of cationic amino acids") "Reactome:R-HSA-375768") -AnnotationAssertion(Annotation(rdfs:label "SLC7A3 (CAT-3)-mediated uptake of cationic amino acids") "Reactome:R-HSA-375770") -AnnotationAssertion(Annotation(rdfs:label "SLC7A1 (CAT-1)-mediated uptake of cationic amino acids") "Reactome:R-HSA-375776") -AnnotationAssertion(Annotation(rdfs:label "SLC7A2, isoform A (CAT-2A)-mediated uptake of cationic amino acids") "Reactome:R-HSA-375790") -AnnotationAssertion(Annotation(rdfs:label "SLC7A10-mediated uptake of small neutral amino acids") "Reactome:R-HSA-376200") -AnnotationAssertion(Annotation(rdfs:label "SLC7A11-mediated exchange of extracellular cysteine and cytosolic glutamate") "Reactome:R-HSA-378513") -AnnotationAssertion(Annotation(rdfs:label "SLC7A7:SLC3A2 exchanges L-Arg for L-Leu, Na+ across the plasma membrane") "Reactome:R-HSA-379415") -AnnotationAssertion(Annotation(rdfs:label "SLC7A6 (y+LAT2)-mediated exchange of extracellular leucine for cytosolic arginine") "Reactome:R-HSA-379426") -AnnotationAssertion(Annotation(rdfs:label "SLC7A9:SLC3A1 exchanges L-Arg, CySS-, L-Lys for L-Leu") "Reactome:R-HSA-379432") -AnnotationAssertion(Annotation(rdfs:label "Defective SLC36A2 does not cotransport Gly, L-Pro with H+ from extracellular region to cytosol") "Reactome:R-HSA-5653850") -AnnotationAssertion(Annotation(rdfs:label "Defective SLC3A1 (in SLC7A9:SLC3A1) does not exchange L-Arg, CySS-, L-Lys for L-Leu") "Reactome:R-HSA-5655702") -AnnotationAssertion(Annotation(rdfs:label "Variant SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol") "Reactome:R-HSA-5659674") -AnnotationAssertion(Annotation(rdfs:label "Defective SLC6A19 does not cotransport neutral amino acids, Na+ from extracellular region to cytosol") "Reactome:R-HSA-5659734") -AnnotationAssertion(Annotation(rdfs:label "Defective SLC6A18 does not transport Gly from extracellular region to cytosol") "Reactome:R-HSA-5659755") -AnnotationAssertion(Annotation(rdfs:label "Variant SLC6A20 does not cotransport L-Pro, Na+ from extracellulare region to cytosol") "Reactome:R-HSA-5660694") -AnnotationAssertion(Annotation(rdfs:label "Defective SLC7A9 (in SLC7A9:SLC3A1) does not exchange L-Arg, CySS-, L-Lys for L-Leu") "Reactome:R-HSA-5660890") -AnnotationAssertion(Annotation(rdfs:label "Defective SLC7A7 does not exchange L-Arg for L-Leu, Na+ across the plasma membrane") "Reactome:R-HSA-5660910") -AnnotationAssertion(Annotation(rdfs:label "Loading of GABA into clathrin sculpted GABA transport vesicle lumen") "Reactome:R-HSA-888592") -AnnotationAssertion(Annotation(rdfs:label "SLC38A9 transports L-Arg from lysosomal lumen to cytosol") "Reactome:R-HSA-8952726") -AnnotationAssertion( "amino acid permease activity") -AnnotationAssertion( "amino acid/choline transmembrane transporter activity") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "general amino acid permease activity") -AnnotationAssertion( "hydroxy/aromatic amino acid permease activity") -AnnotationAssertion( "GO:0015171") -AnnotationAssertion(rdfs:label "amino acid transmembrane transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "GO_REF:0000090") ObjectSomeValuesFrom( )) - -# Class: (acidic amino acid transmembrane transporter activity) - -AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:mtg_transport") Annotation( "ISBN:0815340729") "Enables the transfer of acidic amino acids from one side of a membrane to the other. Acidic amino acids have side chains with a negative charge at pH 7.3.") -AnnotationAssertion( "acidic amino acid transporter activity") -AnnotationAssertion(Annotation(rdfs:label "SLC25A12,13 exchange cytosolic L-Glu for mitochondrial matrix L-Asp") "Reactome:R-HSA-372448") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0015172") -AnnotationAssertion(rdfs:label "acidic amino acid transmembrane transporter activity") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (L-amino acid transmembrane transporter activity) - -AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:jsg") Annotation( "GOC:mah") Annotation( "GOC:mtg_transport") Annotation( "ISBN:0815340729") "Enables the transfer of an L-amino acid from one side of a membrane to the other. L-amino acids are the L-enantiomers of amino acids.") -AnnotationAssertion( "L-amino acid transporter activity") -AnnotationAssertion(Annotation(rdfs:label "Glutamine transport from astrocytes") "Reactome:R-HSA-212614") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0015179") -AnnotationAssertion(rdfs:label "L-amino acid transmembrane transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf(Annotation( "GO_REF:0000090") ObjectSomeValuesFrom( )) - -# Class: (gamma-aminobutyric acid transmembrane transporter activity) - -AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "GOC:mtg_transport") Annotation( "ISBN:0198506732") Annotation( "ISBN:0815340729") "Enables the transfer of gamma-aminobutyric acid from one side of a membrane to the other. Gamma-aminobutyric acid is 4-aminobutyrate (GABA).") -AnnotationAssertion( "4-aminobutanoate transporter activity") -AnnotationAssertion( "4-aminobutyrate transporter activity") -AnnotationAssertion( "GABA transporter activity") -AnnotationAssertion( "betaine/GABA:sodium symporter activity") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0015185") -AnnotationAssertion(rdfs:label "gamma-aminobutyric acid transmembrane transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (nucleobase transmembrane transporter activity) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "Enables the transfer of a nucleobase, any nitrogenous base that is a constituent of a nucleoside, nucleotide, or nucleic acidfrom one side of a membrane to the other.") -AnnotationAssertion( "GO:0015392") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0015205") -AnnotationAssertion(rdfs:label "nucleobase transmembrane transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (adenine transmembrane transporter activity) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Enables the transfer of adenine, 6-aminopurine, from one side of a membrane to the other.") -AnnotationAssertion( "RHEA:34999") -AnnotationAssertion(Annotation(rdfs:label "SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane") "Reactome:R-HSA-163215") -AnnotationAssertion(Annotation(rdfs:label "ARL2:GTP:ARL2BP:SLC25A4 dimer exchanges ATP for ADP across the mitochondrial inner membrane") "Reactome:R-HSA-5672027") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0015207") -AnnotationAssertion(rdfs:label "adenine transmembrane transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (purine nucleoside transmembrane transporter activity) - -AnnotationAssertion(Annotation( "GOC:ai") "Enables the transfer of a purine nucleoside, a purine base covalently bonded to a ribose or deoxyribose sugar, from one side of a membrane to the other.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0015211") -AnnotationAssertion(rdfs:label "purine nucleoside transmembrane transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "GO_REF:0000090") ObjectSomeValuesFrom( )) - -# Class: (nucleotide transmembrane transporter activity) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "Enables the transfer of a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate, from one side of a membrane to the other.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0015215") -AnnotationAssertion(rdfs:label "nucleotide transmembrane transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf(Annotation( "GO_REF:0000090") ObjectSomeValuesFrom( )) - -# Class: (purine nucleotide transmembrane transporter activity) - -AnnotationAssertion(Annotation( "GOC:ai") "Enables the transfer of a purine nucleotide, any compound consisting of a purine nucleoside esterified with (ortho)phosphate, from one side of a membrane to the other.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0015216") -AnnotationAssertion(rdfs:label "purine nucleotide transmembrane transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (ADP transmembrane transporter activity) - -AnnotationAssertion(Annotation( "GOC:ai") "Enables the transfer of ADP, adenosine diphosphate, from one side of a membrane to the other.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0015217") -AnnotationAssertion(rdfs:label "ADP transmembrane transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (choline transmembrane transporter activity) - -AnnotationAssertion(Annotation( "GOC:ai") "Enables the transfer of choline from one side of a membrane to the other. Choline (2-hydroxyethyltrimethylammonium) is an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine.") -AnnotationAssertion( "GO:0005306") -AnnotationAssertion(Annotation(rdfs:label "SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol") "Reactome:R-HSA-429594") -AnnotationAssertion(Annotation(rdfs:label "Cho transports from the extracellular space to the cytosol") "Reactome:R-HSA-444433") -AnnotationAssertion(Annotation(rdfs:label "Defective SLC5A7 does not cotransport Cho, Cl-, Na+ from extracellular region to cytosol") "Reactome:R-HSA-5658483") -AnnotationAssertion(Annotation(rdfs:label "SLC44A1 transports Cho from cytosol to mitochondrial matrix") "Reactome:R-HSA-6797956") -AnnotationAssertion( "choline permease activity") -AnnotationAssertion( "amino acid/choline transmembrane transporter activity") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0015220") -AnnotationAssertion(rdfs:label "choline transmembrane transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (fatty acid transmembrane transporter activity) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "Enables the transfer of fatty acids from one side of a membrane to the other. Fatty acids are aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis.") -AnnotationAssertion( "GO:0015246") -AnnotationAssertion( "fatty-acyl group transporter activity") -AnnotationAssertion(Annotation(rdfs:label "Defective SLC27A4 does not transport LCFAs from extracellular region to cytosol") "Reactome:R-HSA-5627891") -AnnotationAssertion(Annotation(rdfs:label "SLC27A1,4,6 transport LCFAs from extracellular region to cytosol") "Reactome:R-HSA-879585") -AnnotationAssertion( "fatty acyl transporter activity") -AnnotationAssertion( "peroxisomal fatty acyl transporter") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "fatty acid transporter activity") -AnnotationAssertion( "GO:0015245") -AnnotationAssertion(rdfs:label "fatty acid transmembrane transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (inorganic molecular entity transmembrane transporter activity) - -AnnotationAssertion(Annotation( "GOC:mtg_transport") Annotation( "ISBN:0815340729") "Enables the transfer of an inorganic molecular entity from the outside of a cell to the inside of the cell across a membrane. An inorganic molecular entity is a molecular entity that contains no carbon.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/14372"^^xsd:anyURI) -AnnotationAssertion( "inorganic solute uptake transmembrane transporter activity") -AnnotationAssertion( "inorganic uptake permease activity") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0015318") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "inorganic molecular entity transmembrane transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (acetylcholine receptor activity) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "GOC:signaling") "Combining with an acetylcholine receptor ligand and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0015464") -AnnotationAssertion(rdfs:comment "For nicotinic acetylcholine receptors that act as ion channels, instead use 'acetylcholine-gated cation channel activity ; GO:0022848'.") -AnnotationAssertion(rdfs:label "acetylcholine receptor activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (formate transmembrane transporter activity) - -AnnotationAssertion(Annotation( "GOC:ai") "Enables the transfer of formate from one side of a membrane to the other. Formate is also known as methanoate, the anion HCOO- derived from methanoic (formic) acid.") -AnnotationAssertion( "GO:0015659") -AnnotationAssertion( "RHEA:29679") -AnnotationAssertion( "formate uptake permease activity") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "formate uptake transmembrane transporter activity") -AnnotationAssertion( "GO:0015499") -AnnotationAssertion(rdfs:label "formate transmembrane transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (alkane transmembrane transporter activity) - -AnnotationAssertion(Annotation( "GOC:ai") "Enables the transfer of alkanes from one side of a membrane to the other. Alkanes are saturated aliphatic hydrocarbon compounds.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0015567") -AnnotationAssertion(rdfs:label "alkane transmembrane transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "GO_REF:0000090") ObjectSomeValuesFrom( )) - -# Class: (D-ribose transmembrane transporter activity) - -AnnotationAssertion(Annotation( "GOC:mtg_transport") Annotation( "ISBN:0198506732") Annotation( "ISBN:0815340729") "Enables the transfer of D-ribose from one side of a membrane to the other. As beta-D-ribofuranose, D-ribose forms the glycose group of all ribonucleosides, ribonucleotides and ribonucleic acids, and also of ribose phosphates, various glycosides, some coenzymes and some forms of vitamin B12.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0015591") -AnnotationAssertion(rdfs:label "D-ribose transmembrane transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (organophosphate ester transmembrane transporter activity) - -AnnotationAssertion(Annotation( "GOC:mcc") "Enables the transfer of organophosphate esters from one side of a membrane to the other. Organophosphate esters are small organic molecules containing phosphate ester bonds.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0015605") -AnnotationAssertion(rdfs:label "organophosphate ester transmembrane transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (actin cytoskeleton) AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0395825172") Annotation( "ISBN:0815316194") "The part of the cytoskeleton (the internal framework of a cell) composed of actin and associated proteins. Includes actin cytoskeleton-associated complexes.") @@ -64369,124 +23091,12 @@ AnnotationAssertion( "actin cytoskeleton") SubClassOf( ) -# Class: (microtubule cytoskeleton) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0395825172") "The part of the cytoskeleton (the internal framework of a cell) composed of microtubules and associated proteins.") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0015630") -AnnotationAssertion(rdfs:label "microtubule cytoskeleton") -SubClassOf( ) - -# Class: (tubulin binding) - -AnnotationAssertion(Annotation( "GOC:clt") "Binding to monomeric or multimeric forms of tubulin, including microtubules.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0015631") -AnnotationAssertion(rdfs:label "tubulin binding") -SubClassOf( ) - -# Class: (short-chain fatty acid transmembrane transporter activity) - -AnnotationAssertion(Annotation( "GOC:mah") "Enables the transfer of short-chain fatty acids from one side of a membrane to the other. A short-chain fatty acid is a fatty acid with an aliphatic tail of less than 6 carbons.") -AnnotationAssertion( "GO:0015635") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "short-chain fatty acid transporter activity") -AnnotationAssertion( "short-chain fatty acid uptake transporter activity") -AnnotationAssertion( "GO:0015636") -AnnotationAssertion(rdfs:label "short-chain fatty acid transmembrane transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (quaternary ammonium group transmembrane transporter activity) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "Enables the transfer of quaternary ammonium groups from one side of a membrane to the other. Quaternary ammonium groups are any compound that can be regarded as derived from ammonium hydroxide or an ammonium salt by replacement of all four hydrogen atoms of the NH4+ ion by organic groups.") -AnnotationAssertion( "GO:0015202") -AnnotationAssertion( "quaternary amine transmembrane transporter activity") -AnnotationAssertion( "quaternary ammonium compound transporter activity") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0015651") -AnnotationAssertion(rdfs:label "quaternary ammonium group transmembrane transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (alcohol transmembrane transporter activity) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "Enables the transfer of an alcohol from one side of a membrane to the other. An alcohol is any carbon compound that contains a hydroxyl group.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0015665") -AnnotationAssertion(rdfs:label "alcohol transmembrane transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (gas transport) - -AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of substances that are gaseous in normal living conditions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0015669") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "gas transport") -SubClassOf( ) - -# Class: (carbon dioxide transport) - -AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of carbon dioxide (CO2) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0015670") -AnnotationAssertion(rdfs:label "carbon dioxide transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (oxygen transport) - -AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of oxygen (O2) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0015671") -AnnotationAssertion(rdfs:label "oxygen transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (organic cation transport) - -AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of organic cations into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organic cations are atoms or small molecules with a positive charge which contain carbon in covalent linkage.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0015695") -AnnotationAssertion(rdfs:label "organic cation transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (quaternary ammonium group transport) - -AnnotationAssertion(Annotation( "GOC:ai") Annotation( "ISBN:0198506732") "The directed movement into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore of quaternary ammonium compounds, any compound that can be regarded as derived from ammonium hydroxide or an ammonium salt by replacement of all four hydrogen atoms of the NH4+ ion by organic groups.") -AnnotationAssertion( "GO:0015845") -AnnotationAssertion( "quaternary amine transport") -AnnotationAssertion( "quaternary ammonium compound transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0015697") -AnnotationAssertion(rdfs:label "quaternary ammonium group transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (inorganic anion transport) - -AnnotationAssertion(Annotation( "GOC:krc") "The directed movement of inorganic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Inorganic anions are atoms or small molecules with a negative charge which do not contain carbon in covalent linkage.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0015698") -AnnotationAssertion(rdfs:label "inorganic anion transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (bicarbonate transport) AnnotationAssertion(Annotation( "GOC:krc") "The directed movement of bicarbonate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0015701") AnnotationAssertion(rdfs:label "bicarbonate transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (organic anion transport) - -AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:krc") "The directed movement of organic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organic anions are atoms or small molecules with a negative charge which contain carbon in covalent linkage.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0015711") -AnnotationAssertion(rdfs:label "organic anion transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (monocarboxylic acid transport) @@ -64494,7 +23104,6 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:0015718") AnnotationAssertion(rdfs:label "monocarboxylic acid transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) # Class: (bile acid and bile salt transport) @@ -64505,74 +23114,10 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0015721") AnnotationAssertion(rdfs:label "bile acid and bile salt transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ) -# Class: (bilirubin transport) - -AnnotationAssertion(Annotation( "GOC:krc") "The directed movement of bilirubin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0015723") -AnnotationAssertion(rdfs:label "bilirubin transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (formate transport) - -AnnotationAssertion(Annotation( "GOC:krc") "The directed movement of formate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0015724") -AnnotationAssertion(rdfs:label "formate transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (organophosphate ester transport) - -AnnotationAssertion(Annotation( "GOC:mcc") "The directed movement of organophosphate esters into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organophosphate esters are small organic molecules containing phosphate ester bonds.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0015748") -AnnotationAssertion(rdfs:label "organophosphate ester transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (monosaccharide transmembrane transport) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:vw") Annotation( "GO_REF:0000069") "The process in which a monosaccharide is transported across a lipid bilayer, from one side of a membrane to the other. Monosaccharides are the simplest carbohydrates; they are polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides.") -AnnotationAssertion( "vw") -AnnotationAssertion( "2017-02-19T10:41:27Z") -AnnotationAssertion( "GO:1905950") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "monosaccharide transport") -AnnotationAssertion( "GO:0015749") -AnnotationAssertion(rdfs:label "monosaccharide transmembrane transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (pentose transmembrane transport) - -AnnotationAssertion(Annotation( "GOC:ai") "The process in which pentose is transported across a lipid bilayer, from one side of a membrane to the other. A pentose is any aldose with a chain of five carbon atoms in the molecule.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "pentose transport") -AnnotationAssertion( "GO:0015750") -AnnotationAssertion(rdfs:label "pentose transmembrane transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (D-ribose transmembrane transport) - -AnnotationAssertion(Annotation( "GOC:ai") "The process in which D-ribose is transported across a lipid bilayer, from one side of a membrane to the other. As beta-D-ribofuranose, D-ribose forms the glycose group of all ribonucleosides, ribonucleotides and ribonucleic acids, and also of ribose phosphates, various glycosides, some coenzymes and some forms of vitamin B12.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "D-ribose transport") -AnnotationAssertion( "GO:0015752") -AnnotationAssertion(rdfs:label "D-ribose transmembrane transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (polysaccharide transport) - -AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of polysaccharides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A polysaccharide is a polymer of many (typically more than 10) monosaccharide residues linked glycosidically.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0015774") -AnnotationAssertion(rdfs:label "polysaccharide transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (acidic amino acid transport) AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of acidic amino acids, amino acids with a pH below 7, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") @@ -64581,38 +23126,6 @@ AnnotationAssertion( "acidic amino acid transport") SubClassOf( ) -# Class: (L-amino acid transport) - -AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:jsg") Annotation( "GOC:mah") "The directed movement of L-enantiomer amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0015807") -AnnotationAssertion(rdfs:label "L-amino acid transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (gamma-aminobutyric acid transport) - -AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198506732") "The directed movement of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion( "4-aminobutanoate transport") -AnnotationAssertion( "4-aminobutyrate transport") -AnnotationAssertion( "GABA transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0015812") -AnnotationAssertion(rdfs:comment "See also the biological process term 'neurotransmitter transport ; GO:0006836'.") -AnnotationAssertion(rdfs:label "gamma-aminobutyric acid transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (L-glutamate transmembrane transport) - -AnnotationAssertion(Annotation( "PMID:21307582") "The directed movement of L-glutamate across a membrane.") -AnnotationAssertion( "GO:0089711") -AnnotationAssertion( "L-glutamate transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "mitochondrial aspartate/glutamate transport") -AnnotationAssertion( "GO:0015813") -AnnotationAssertion(rdfs:label "L-glutamate transmembrane transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ) - # Class: (peptide transport) AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") @@ -64620,41 +23133,9 @@ AnnotationAssertion( "GO:0015833") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "peptide transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) -# Class: (amine transport) - -AnnotationAssertion(Annotation( "GOC:ai") Annotation( "ISBN:0198506732") "The directed movement of amines, including polyamines, organic compounds containing one or more amino groups, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "amine/polyamine transport") -AnnotationAssertion( "GO:0015837") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "amine transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (monoamine transport) - -AnnotationAssertion(Annotation( "GOC:mah") "The directed movement of monoamines, organic compounds that contain one amino group that is connected to an aromatic ring by an ethylene group (-CH2-CH2-), into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion( "GO:0015873") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0015844") -AnnotationAssertion(rdfs:label "monoamine transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (organic acid transport) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "The directed movement of organic acids, any acidic compound containing carbon in covalent linkage, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0015849") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "organic acid transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (organic hydroxy compound transport) AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of an organic hydroxy compound (organic alcohol) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. An organic hydroxy compound is an organic compound having at least one hydroxy group attached to a carbon atom.") @@ -64662,222 +23143,9 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0015850") AnnotationAssertion(rdfs:label "organic hydroxy compound transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) -# Class: (nucleobase transport) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "The directed movement of a nucleobase, any nitrogenous base that is a constituent of a nucleoside, nucleotide, or nucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion(Annotation( "GOC:mah") "nucleobase transmembrane transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0015851") -AnnotationAssertion(rdfs:label "nucleobase transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (adenine transport) - -AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198506732") "The directed movement of adenine, 6-aminopurine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion(Annotation( "GOC:mah") "adenine transmembrane transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0015853") -AnnotationAssertion(rdfs:label "adenine transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (nucleoside transport) - -AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of a nucleoside, a nucleobase linked to either beta-D-ribofuranose (ribonucleoside) or 2-deoxy-beta-D-ribofuranose, (a deoxyribonucleotide), into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0015858") -AnnotationAssertion(rdfs:label "nucleoside transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (intracellular nucleoside transport) - -AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of a nucleoside, a nucleobase linked to either beta-D-ribofuranose (ribonucleoside) or 2-deoxy-beta-D-ribofuranose, (a deoxyribonucleotide), within a cell.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0015859") -AnnotationAssertion(rdfs:label "intracellular nucleoside transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (purine nucleoside transmembrane transport) - -AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:vw") "The process in which a purine nucleoside is transported across a membrane. A purine nucleoside is a purine base covalently bonded to a ribose or deoxyribose sugar.") -AnnotationAssertion( "GO:0035427") -AnnotationAssertion(Annotation( "GOC:vw") "purine nucleoside transport") -AnnotationAssertion( "purine nucleoside membrane transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0015860") -AnnotationAssertion(rdfs:comment "Note that this term is not intended for use in annotating lateral movement within membranes.") -AnnotationAssertion(rdfs:label "purine nucleoside transmembrane transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (purine nucleotide transport) - -AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of a purine nucleotide, any compound consisting of a purine nucleoside esterified with (ortho)phosphate, into, out of or within a cell.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0015865") -AnnotationAssertion(rdfs:label "purine nucleotide transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (ADP transport) - -AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of ADP, adenosine diphosphate, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0015866") -AnnotationAssertion(rdfs:label "ADP transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (ATP transport) - -AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of ATP, adenosine triphosphate, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0015867") -AnnotationAssertion(rdfs:label "ATP transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (purine ribonucleotide transport) - -AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of a purine ribonucleotide, any compound consisting of a purine ribonucleoside (a purine organic base attached to a ribose sugar) esterified with (ortho)phosphate, into, out of or within a cell.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0015868") -AnnotationAssertion(rdfs:label "purine ribonucleotide transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (protein-DNA complex transport) - -AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of protein-DNA complexes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion(Annotation( "GOC:mah") "DNA-protein complex transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0015869") -AnnotationAssertion(rdfs:label "protein-DNA complex transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (acetylcholine transport) - -AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of acetylcholine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Acetylcholine is an acetic acid ester of the organic base choline and functions as a neurotransmitter, released at the synapses of parasympathetic nerves and at neuromuscular junctions.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0015870") -AnnotationAssertion(rdfs:label "acetylcholine transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (choline transport) - -AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of choline into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Choline (2-hydroxyethyltrimethylammonium) is an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0015871") -AnnotationAssertion(rdfs:label "choline transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (dopamine transport) - -AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of dopamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Dopamine is a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0015872") -AnnotationAssertion(rdfs:label "dopamine transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (norepinephrine transport) - -AnnotationAssertion(Annotation( "GOC:ai") Annotation( "ISBN:0198506732") "The directed movement of norepinephrine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Norepinephrine (3,4-dihydroxyphenyl-2-aminoethanol) is a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine.") -AnnotationAssertion( "levarterenol transport") -AnnotationAssertion( "noradrenaline transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0015874") -AnnotationAssertion(rdfs:label "norepinephrine transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (alkane transport) - -AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of alkanes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Alkanes are saturated aliphatic hydrocarbon compounds.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0015895") -AnnotationAssertion(rdfs:label "alkane transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (fatty acid transport) - -AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of fatty acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Fatty acids are aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0015908") -AnnotationAssertion(rdfs:label "fatty acid transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (short-chain fatty acid transport) - -AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of short-chain fatty acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A short-chain fatty acid is a fatty acid with an aliphatic tail of less than 6 carbons.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0015912") -AnnotationAssertion(rdfs:label "short-chain fatty acid transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (short-chain fatty acid transmembrane transport) - -AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of short-chain fatty acids into a cell or organelle. A short-chain fatty acid is a fatty acid with an aliphatic tail of less than 6 carbons.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/24587"^^xsd:anyURI) -AnnotationAssertion( "short-chain fatty acid uptake") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "short-chain fatty acid import") -AnnotationAssertion( "GO:0015913") -AnnotationAssertion(rdfs:label "short-chain fatty acid transmembrane transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (phospholipid transport) - -AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of phospholipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Phospholipids are any lipids containing phosphoric acid as a mono- or diester.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0015914") -AnnotationAssertion(rdfs:label "phospholipid transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (nucleobase-containing compound transport) - -AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "nucleobase, nucleoside, nucleotide and nucleic acid transport") -AnnotationAssertion( "GO:0015931") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "nucleobase-containing compound transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (nucleobase-containing compound transmembrane transporter activity) - -AnnotationAssertion(Annotation( "GOC:ai") "Enables the transfer of nucleobases, nucleosides, nucleotides and nucleic acids from one side of a membrane to the other.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "nucleobase, nucleoside, nucleotide and nucleic acid transmembrane transporter activity") -AnnotationAssertion( "GO:0015932") -AnnotationAssertion(rdfs:label "nucleobase-containing compound transmembrane transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (formate metabolic process) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving formate, also known as methanoate, the anion HCOO- derived from methanoic (formic) acid.") -AnnotationAssertion( "formate metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0015942") -AnnotationAssertion(rdfs:label "formate metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (formate biosynthetic process) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of formate, also known as methanoate, the anion HCOO- derived from methanoic (formic) acid.") -AnnotationAssertion( "formate anabolism") -AnnotationAssertion( "formate biosynthesis") -AnnotationAssertion( "formate formation") -AnnotationAssertion( "formate synthesis") -AnnotationAssertion( "formic acid biosynthesis") -AnnotationAssertion( "formic acid biosynthetic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0015943") -AnnotationAssertion(rdfs:label "formate biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (energy derivation by oxidation of organic compounds) AnnotationAssertion(Annotation( "GOC:mah") "The chemical reactions and pathways by which a cell derives energy from organic compounds; results in the oxidation of the compounds from which energy is released.") @@ -64915,44 +23183,6 @@ AnnotationAssertion(rdfs:label "memb SubClassOf( ) DisjointClasses( ) -# Class: (lipid catabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways resulting in the breakdown of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.") -AnnotationAssertion( "GO:0006724") -AnnotationAssertion( "GO:0044240") -AnnotationAssertion( "Wikipedia:Lipid_catabolism") -AnnotationAssertion( "lipid breakdown") -AnnotationAssertion( "lipid catabolism") -AnnotationAssertion( "lipid degradation") -AnnotationAssertion( "lipolysis") -AnnotationAssertion( "multicellular organism lipid catabolic process") -AnnotationAssertion( "multicellular organismal lipid catabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0016042") -AnnotationAssertion(rdfs:label "lipid catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cellular component organization) - -AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:jl") Annotation( "GOC:mah") "A process that results in the assembly, arrangement of constituent parts, or disassembly of a cellular component.") -AnnotationAssertion( "GO:0044235") -AnnotationAssertion( "GO:0071842") -AnnotationAssertion( "cell organisation") -AnnotationAssertion(Annotation( "GOC:mah") "cellular component organisation at cellular level") -AnnotationAssertion(Annotation( "GOC:mah") "cellular component organisation in other organism") -AnnotationAssertion( "cellular component organization at cellular level") -AnnotationAssertion( "cellular component organization in other organism") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:mah") "cell organization and biogenesis") -AnnotationAssertion( "GO:0016043") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "cellular component organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - # Class: (detection of temperature stimulus) AnnotationAssertion(Annotation( "GOC:hb") "The series of events in which a temperature stimulus (hot or cold) is received and converted into a molecular signal.") @@ -64984,58 +23214,9 @@ AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "cell growth") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) -# Class: (vesicle organization) - -AnnotationAssertion(Annotation( "GOC:mah") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vesicle.") -AnnotationAssertion( "vesicle organisation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:mah") "vesicle organization and biogenesis") -AnnotationAssertion( "GO:0016050") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "vesicle organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (carbohydrate biosynthetic process) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.") -AnnotationAssertion( "GO:0006093") -AnnotationAssertion( "anabolic carbohydrate metabolic process") -AnnotationAssertion( "anabolic carbohydrate metabolism") -AnnotationAssertion( "carbohydrate anabolism") -AnnotationAssertion( "carbohydrate biosynthesis") -AnnotationAssertion( "carbohydrate formation") -AnnotationAssertion( "carbohydrate synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0016051") -AnnotationAssertion(rdfs:label "carbohydrate biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (carbohydrate catabolic process) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.") -AnnotationAssertion( "jl") -AnnotationAssertion( "2012-10-23T16:34:39Z") -AnnotationAssertion( "GO:0006095") -AnnotationAssertion( "GO:0044276") -AnnotationAssertion( "GO:0044724") -AnnotationAssertion( "carbohydrate breakdown") -AnnotationAssertion( "carbohydrate catabolism") -AnnotationAssertion( "carbohydrate degradation") -AnnotationAssertion( "catabolic carbohydrate metabolic process") -AnnotationAssertion( "catabolic carbohydrate metabolism") -AnnotationAssertion( "multicellular organismal carbohydrate catabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "single-organism carbohydrate catabolic process") -AnnotationAssertion( "GO:0016052") -AnnotationAssertion(rdfs:label "carbohydrate catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (organic acid biosynthetic process) AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of organic acids, any acidic compound containing carbon in covalent linkage.") @@ -65046,292 +23227,11 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0016053") AnnotationAssertion(rdfs:label "organic acid biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) -# Class: (organic acid catabolic process) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of organic acids, any acidic compound containing carbon in covalent linkage.") -AnnotationAssertion( "organic acid breakdown") -AnnotationAssertion( "organic acid catabolism") -AnnotationAssertion( "organic acid degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0016054") -AnnotationAssertion(rdfs:label "organic acid catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of membrane potential in photoreceptor cell) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:hb") Annotation( "GOC:tb") "Hyperpolarization (vertebrates) or depolarization (invertebrates) of the photoreceptor cell membrane via closing/opening of cation specific channels as a result of signals generated by rhodopsin activation by a photon.") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "changes in polarization state of photoreceptor cell membrane") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0016057") -AnnotationAssertion(rdfs:label "regulation of membrane potential in photoreceptor cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (immunoglobulin mediated immune response) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GO_REF:0000022") Annotation( "ISBN:0781735149") "An immune response mediated by immunoglobulins, whether cell-bound or in solution.") -AnnotationAssertion( "antibody-mediated immune response") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0016064") -AnnotationAssertion(rdfs:label "immunoglobulin mediated immune response") -SubClassOf( ) - -# Class: (RNA metabolic process) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "The cellular chemical reactions and pathways involving RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage.") -AnnotationAssertion( "RNA metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0016070") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "RNA metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (synaptic vesicle exocytosis) - -AnnotationAssertion(Annotation( "GOC:jid") Annotation( "GOC:lmg") "Fusion of intracellular membrane-bounded vesicles with the pre-synaptic membrane of the neuronal cell resulting in release of neurotransmitter into the synaptic cleft.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0016079") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "synaptic vesicle exocytosis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (sesquiterpenoid biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways resulting in the formation of sesquiterpenoid compounds, terpenoids with three isoprene units.") -AnnotationAssertion( "sesquiterpenoid anabolism") -AnnotationAssertion( "sesquiterpenoid biosynthesis") -AnnotationAssertion( "sesquiterpenoid formation") -AnnotationAssertion( "sesquiterpenoid synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0016106") -AnnotationAssertion(rdfs:label "sesquiterpenoid biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (sesquiterpenoid catabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways resulting in the breakdown of sesquiterpenoid compounds, terpenoids with three isoprene units.") -AnnotationAssertion( "sesquiterpenoid breakdown") -AnnotationAssertion( "sesquiterpenoid catabolism") -AnnotationAssertion( "sesquiterpenoid degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0016107") -AnnotationAssertion(rdfs:label "sesquiterpenoid catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (tetraterpenoid metabolic process) - -AnnotationAssertion(Annotation( "ISBN:0198547684") "The chemical reactions and pathways involving tetraterpenoid compounds, terpenoids with eight isoprene units.") -AnnotationAssertion( "tetraterpenoid metabolism") -AnnotationAssertion( "tetraterpene metabolic process") -AnnotationAssertion( "tetraterpene metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0016108") -AnnotationAssertion(rdfs:label "tetraterpenoid metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (tetraterpenoid biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways resulting in the formation of tetraterpenoid compounds, terpenoids with eight isoprene units.") -AnnotationAssertion( "tetraterpenoid anabolism") -AnnotationAssertion( "tetraterpenoid biosynthesis") -AnnotationAssertion( "tetraterpenoid formation") -AnnotationAssertion( "tetraterpenoid synthesis") -AnnotationAssertion( "tetraterpene biosynthesis") -AnnotationAssertion( "tetraterpene biosynthetic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0016109") -AnnotationAssertion(rdfs:label "tetraterpenoid biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (tetraterpenoid catabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways resulting in the breakdown of tetraterpenoid compounds, terpenoids with eight isoprene units.") -AnnotationAssertion( "tetraterpenoid breakdown") -AnnotationAssertion( "tetraterpenoid catabolism") -AnnotationAssertion( "tetraterpenoid degradation") -AnnotationAssertion( "tetraterpene catabolic process") -AnnotationAssertion( "tetraterpene catabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0016110") -AnnotationAssertion(rdfs:label "tetraterpenoid catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (terpenoid biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways resulting in the formation of terpenoids, any member of a class of compounds characterized by an isoprenoid chemical structure.") -AnnotationAssertion( "Wikipedia:Terpenoid") -AnnotationAssertion( "terpenoid anabolism") -AnnotationAssertion( "terpenoid biosynthesis") -AnnotationAssertion( "terpenoid formation") -AnnotationAssertion( "terpenoid synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0016114") -AnnotationAssertion(rdfs:label "terpenoid biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (terpenoid catabolic process) - -AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways resulting in the breakdown of terpenoids, any member of a class of compounds characterized by an isoprenoid chemical structure.") -AnnotationAssertion( "terpenoid breakdown") -AnnotationAssertion( "terpenoid catabolism") -AnnotationAssertion( "terpenoid degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0016115") -AnnotationAssertion(rdfs:label "terpenoid catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (carotenoid metabolic process) - -AnnotationAssertion(Annotation( "ISBN:0198547684") "The chemical reactions and pathways involving carotenoids, tetraterpenoid compounds in which two units of 4 isoprenoid residues joined head-to-tail are themselves joined tail-to-tail.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "carotenoid metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0016116") -AnnotationAssertion(rdfs:label "carotenoid metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) -SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) -SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) -DisjointClasses( ObjectSomeValuesFrom( )) -DisjointClasses( ObjectSomeValuesFrom( )) - -# Class: (carotenoid biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways resulting in the formation of carotenoids, tetraterpenoid compounds in which two units of 4 isoprenoid residues joined head-to-tail are themselves joined tail-to-tail.") -AnnotationAssertion( "MetaCyc:CAROTENOID-PWY") -AnnotationAssertion( "carotenoid anabolism") -AnnotationAssertion( "carotenoid biosynthesis") -AnnotationAssertion( "carotenoid formation") -AnnotationAssertion( "carotenoid synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0016117") -AnnotationAssertion(rdfs:label "carotenoid biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (carotenoid catabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways resulting in the breakdown of carotenoids, tetraterpenoid compounds in which two units of 4 isoprenoid residues joined head-to-tail are themselves joined tail-to-tail.") -AnnotationAssertion( "carotenoid breakdown") -AnnotationAssertion( "carotenoid catabolism") -AnnotationAssertion( "carotenoid degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0016118") -AnnotationAssertion(rdfs:label "carotenoid catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (carotene metabolic process) - -AnnotationAssertion(Annotation( "ISBN:0198547684") "The chemical reactions and pathways involving carotenes, hydrocarbon carotenoids.") -AnnotationAssertion( "carotene metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0016119") -AnnotationAssertion(rdfs:label "carotene metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (carotene biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways resulting in the formation of carotenes, hydrocarbon carotenoids.") -AnnotationAssertion( "carotene anabolism") -AnnotationAssertion( "carotene biosynthesis") -AnnotationAssertion( "carotene formation") -AnnotationAssertion( "carotene synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0016120") -AnnotationAssertion(rdfs:label "carotene biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (carotene catabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways resulting in the breakdown of carotenes, hydrocarbon carotenoids.") -AnnotationAssertion( "carotene breakdown") -AnnotationAssertion( "carotene catabolism") -AnnotationAssertion( "carotene degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0016121") -AnnotationAssertion(rdfs:label "carotene catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (xanthophyll metabolic process) - -AnnotationAssertion(Annotation( "ISBN:0198547684") "The chemical reactions and pathways involving xanthophylls, oxygen-containing carotenoids.") -AnnotationAssertion( "xanthophyll metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0016122") -AnnotationAssertion(rdfs:label "xanthophyll metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (xanthophyll biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways resulting in the formation of xanthophylls, oxygen-containing carotenoids.") -AnnotationAssertion( "xanthophyll anabolism") -AnnotationAssertion( "xanthophyll biosynthesis") -AnnotationAssertion( "xanthophyll formation") -AnnotationAssertion( "xanthophyll synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0016123") -AnnotationAssertion(rdfs:label "xanthophyll biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (xanthophyll catabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways resulting in the breakdown of xanthophylls, oxygen-containing carotenoids.") -AnnotationAssertion( "xanthophyll breakdown") -AnnotationAssertion( "xanthophyll catabolism") -AnnotationAssertion( "xanthophyll degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0016124") -AnnotationAssertion(rdfs:label "xanthophyll catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (vesicle-mediated transport) - -AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:mah") Annotation( "ISBN:08789310662000") "A cellular transport process in which transported substances are moved in membrane-bounded vesicles; transported substances are enclosed in the vesicle lumen or located in the vesicle membrane. The process begins with a step that directs a substance to the forming vesicle, and includes vesicle budding and coating. Vesicles are then targeted to, and fuse with, an acceptor membrane.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/25421"^^xsd:anyURI) -AnnotationAssertion( "GO:0006899") -AnnotationAssertion( "vesicle transport") -AnnotationAssertion(Annotation( "GOC:mah") "vesicular transport") -AnnotationAssertion( "nonselective vesicle transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "protein sorting along secretory pathway") -AnnotationAssertion( "vesicle trafficking") -AnnotationAssertion( "GO:0016192") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "vesicle-mediated transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of striated muscle tissue development) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of striated muscle development.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0016202") -AnnotationAssertion(rdfs:label "regulation of striated muscle tissue development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - # Class: (kinase activity) AnnotationAssertion(Annotation( "ISBN:0198506732") "Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.") @@ -65350,48 +23250,6 @@ AnnotationAssertion(rdfs:label "kina SubClassOf( ) SubClassOf( ObjectHasSelf()) -# Class: (phosphorylation) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide.") -AnnotationAssertion( "Wikipedia:Phosphorylation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0016310") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "phosphorylation") -SubClassOf( ) - -# Class: (mushroom body development) - -AnnotationAssertion(Annotation( "PMID:8790424") "The process whose specific outcome is the progression of the mushroom body over time, from its formation to the mature structure. The mushroom body is composed of the prominent neuropil structures of the insect central brain, thought to be crucial for olfactory associated learning. These consist mainly of a bulbous calyx and tightly packaged arrays of thin parallel fibers of the Kenyon cells.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0016319") -AnnotationAssertion(rdfs:label "mushroom body development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (female meiosis chromosome segregation) - -AnnotationAssertion(Annotation( "GOC:ai") "The cell cycle process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets during the meiotic cell cycle in a female.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0016321") -AnnotationAssertion(rdfs:label "female meiosis chromosome segregation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (oocyte microtubule cytoskeleton organization) - -AnnotationAssertion(Annotation( "GOC:mtg_sensu") Annotation( "PMID:11231123") "Formation and maintenance of a polarized microtubule array originating from a microtubule-organizing center (MTOC) in the oocyte. An example of this is found in Drosophila melanogaster.") -AnnotationAssertion( "GO:0048130") -AnnotationAssertion( "oocyte microtubule cytoskeleton organisation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0016325") -AnnotationAssertion(rdfs:label "oocyte microtubule cytoskeleton organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (morphogenesis of embryonic epithelium) AnnotationAssertion(Annotation( "GOC:jl") "The process in which the anatomical structures of embryonic epithelia are generated and organized.") @@ -65401,53 +23259,6 @@ AnnotationAssertion(rdfs:label "morp SubClassOf( ) SubClassOf( ) -# Class: (dendrite development) - -AnnotationAssertion(Annotation( "GOC:aruk") Annotation( "GOC:bc") Annotation( "GOC:jl") Annotation( "ISBN:0198506732") Annotation( "PMID:22683681") "The process whose specific outcome is the progression of the dendrite over time, from its formation to the mature structure.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0016358") -AnnotationAssertion(rdfs:label "dendrite development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (somatic cell DNA recombination) - -AnnotationAssertion(Annotation( "GOC:ma") "Recombination occurring within or between DNA molecules in somatic cells.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0016444") -AnnotationAssertion(rdfs:label "somatic cell DNA recombination") -SubClassOf( ) - -# Class: (somatic diversification of immunoglobulins) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:ma") Annotation( "ISBN:0781735149") "The somatic process that results in the generation of sequence diversity of immunoglobulins.") -AnnotationAssertion( "somatic diversification of antibodies") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0016445") -AnnotationAssertion(rdfs:label "somatic diversification of immunoglobulins") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (somatic hypermutation of immunoglobulin genes) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") Annotation( "PMID:11205330") Annotation( "PMID:11205333") Annotation( "PMID:14975236") Annotation( "PMID:7813007") "Mutations occurring somatically that result in amino acid changes in the rearranged V regions of immunoglobulins.") -AnnotationAssertion( "somatic hypermutation of antibody genes") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0016446") -AnnotationAssertion(rdfs:label "somatic hypermutation of immunoglobulin genes") -SubClassOf( ) -SubClassOf( ) - -# Class: (somatic recombination of immunoglobulin gene segments) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") "The process in which immunoglobulin genes are formed through recombination of the germline genetic elements, as known as immunoglobulin gene segments, within a single locus.") -AnnotationAssertion( "somatic recombination of antibody gene segments") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0016447") -AnnotationAssertion(rdfs:label "somatic recombination of immunoglobulin gene segments") -SubClassOf( ) -SubClassOf( ) - # Class: (cell migration) AnnotationAssertion(Annotation( "GOC:cjm") Annotation( "GOC:dph") Annotation( "GOC:ems") Annotation( "GOC:pf") Annotation( "Wikipedia:Cell_migration") "The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues.") @@ -65462,14 +23273,6 @@ SubClassOf( ObjectComplementOf(Object SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) DisjointClasses( ObjectSomeValuesFrom( )) -# Class: (cytosolic transport) - -AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of substances or organelles within the cytosol.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0016482") -AnnotationAssertion(rdfs:label "cytosolic transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (protein processing) AnnotationAssertion(Annotation( "GOC:curators") Annotation( "GOC:jl") Annotation( "GOC:jsg") "Any protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein. Protein maturation is the process leading to the attainment of the full functional capacity of a protein.") @@ -65485,81 +23288,6 @@ AnnotationAssertion(rdfs:label "prot SubClassOf( ) SubClassOf( ) -# Class: (peptide hormone processing) - -AnnotationAssertion(Annotation( "GOC:mah") "The generation of a mature peptide hormone by posttranslational processing of a prohormone.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0016486") -AnnotationAssertion(rdfs:label "peptide hormone processing") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (protein-hormone receptor activity) - -AnnotationAssertion(Annotation( "GOC:mah") "Combining with a protein hormone to initiate a change in cell activity.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0016500") -AnnotationAssertion(rdfs:label "protein-hormone receptor activity") -SubClassOf( ) - -# Class: (nucleotide receptor activity) - -AnnotationAssertion(Annotation( "GOC:signaling") Annotation( "ISBN:0198506732") "Combining with a nucleotide and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. A nucleotide is a compound that consists of a nucleoside esterified with a phosphate molecule.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0016502") -AnnotationAssertion(rdfs:label "nucleotide receptor activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (negative regulation of angiogenesis) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of angiogenesis.") -AnnotationAssertion( "down regulation of angiogenesis") -AnnotationAssertion( "down-regulation of angiogenesis") -AnnotationAssertion( "downregulation of angiogenesis") -AnnotationAssertion( "inhibition of angiogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0016525") -AnnotationAssertion(rdfs:label "negative regulation of angiogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (sarcoplasm) - -AnnotationAssertion(Annotation( "ISBN:0198547684") "The cytoplasm of a muscle cell; includes the sarcoplasmic reticulum.") -AnnotationAssertion( ) -AnnotationAssertion( "Wikipedia:Sarcoplasm") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0016528") -AnnotationAssertion(rdfs:label "sarcoplasm") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) -DisjointClasses( ObjectSomeValuesFrom( )) - -# Class: (glutamate binding) - -AnnotationAssertion(Annotation( "GOC:ai") "Binding to glutamate, the anion of 2-aminopentanedioic acid.") -AnnotationAssertion( "glutamic acid binding") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0016595") -AnnotationAssertion(rdfs:label "glutamate binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (amino acid binding) - -AnnotationAssertion(Annotation( "GOC:ai") "Binding to an amino acid, organic acids containing one or more amino substituents.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0016597") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "amino acid binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (transferase activity) AnnotationAssertion(Annotation( "ISBN:0198506732") "Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2.") @@ -65594,187 +23322,6 @@ AnnotationAssertion(rdfs:comment "No AnnotationAssertion(rdfs:label "transferase activity, transferring phosphorus-containing groups") SubClassOf( ) -# Class: (phosphotransferase activity, alcohol group as acceptor) - -AnnotationAssertion(Annotation( "GOC:jl") "Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to an alcohol group (acceptor).") -AnnotationAssertion( "EC:2.7.1.-") -AnnotationAssertion(Annotation(rdfs:label "abacavir + AMP => abacavir monophosphate + adenosine") "Reactome:R-HSA-2161193") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0016773") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "phosphotransferase activity, alcohol group as acceptor") -SubClassOf( ) - -# Class: (hydrolase activity) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc.") -AnnotationAssertion( "EC:3.-.-.-") -AnnotationAssertion(Annotation(rdfs:label "Partial proteolysis of antigen in phagolysosomes") "Reactome:R-HSA-1236938") -AnnotationAssertion(Annotation(rdfs:label "Production of AA by iPLA2 upon FCGR activation") "Reactome:R-HSA-2029475") -AnnotationAssertion(Annotation(rdfs:label "ABHD4 hydrolyses NAPE") "Reactome:R-HSA-5694583") -AnnotationAssertion(Annotation(rdfs:label "ABHD14B hydrolyses PNPB") "Reactome:R-HSA-5695964") -AnnotationAssertion(Annotation(rdfs:label "CMBL hydrolyses OM to OLMS") "Reactome:R-HSA-6786190") -AnnotationAssertion(Annotation(rdfs:label "HDHD1:Mg2+ dephosphorylates PURIDP") "Reactome:R-HSA-6788295") -AnnotationAssertion(Annotation(rdfs:label "ENPPs hydrolyse CoA-SH to PPANT, PAP") "Reactome:R-HSA-8938314") -AnnotationAssertion(Annotation(rdfs:label "Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate") "Reactome:R-HSA-8952137") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0016787") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "hydrolase activity") -SubClassOf( ) - -# Class: (hydrolase activity, acting on ester bonds) - -AnnotationAssertion(Annotation( "GOC:jl") "Catalysis of the hydrolysis of any ester bond.") -AnnotationAssertion( "EC:3.1.-.-") -AnnotationAssertion(Annotation(rdfs:label "uPAR-acyl-GPI + H2O -> uPAR + long-chain fatty acid") "Reactome:R-HSA-162729") -AnnotationAssertion(Annotation(rdfs:label "Butyrylcholinesterase hydrolyzes acyl Ghrelin") "Reactome:R-HSA-9023617") -AnnotationAssertion(Annotation(rdfs:label "Platelet-activating factor acetylhydrolase (PLA2G7) hydrolyzes acyl Ghrelin") "Reactome:R-HSA-9023619") -AnnotationAssertion(Annotation(rdfs:label "BCHE hydrolyzes ASA-") "Reactome:R-HSA-9749609") -AnnotationAssertion( "esterase activity") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0016788") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "hydrolase activity, acting on ester bonds") -SubClassOf( ) - -# Class: (G protein-coupled acetylcholine receptor activity) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:fj") Annotation( "GOC:mah") "Combining with acetylcholine and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.") -AnnotationAssertion( "GO:0004981") -AnnotationAssertion( "G protein coupled acetylcholine receptor activity") -AnnotationAssertion( "G-protein coupled acetylcholine receptor activity") -AnnotationAssertion(Annotation( "GOC:bf") "acetylcholine receptor activity, G-protein coupled") -AnnotationAssertion( "metabotropic acetylcholine receptor activity") -AnnotationAssertion( "muscarinic acetylcholine receptor activity") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0016907") -AnnotationAssertion(rdfs:label "G protein-coupled acetylcholine receptor activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (GABA receptor activity) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "GOC:signaling") Annotation( "PMID:10637650") "Combining with gamma-aminobutyric acid (GABA), and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. (GABA, 4-aminobutyrate) is an amino acid which acts as a neurotransmitter in some organisms.") -AnnotationAssertion( "4-aminobutanoate receptor activity") -AnnotationAssertion( "4-aminobutyrate receptor activity") -AnnotationAssertion( "GABA binding") -AnnotationAssertion( "gamma-aminobutyrate binding") -AnnotationAssertion( "gamma-aminobutyric acid binding") -AnnotationAssertion( "gamma-aminobutyric acid receptor activity") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0016917") -AnnotationAssertion(rdfs:comment "See also the molecular function term 'neurotransmitter receptor activity ; GO:0030594'.") -AnnotationAssertion(rdfs:label "GABA receptor activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (peptide hormone binding) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0198506732") "Binding to a peptide with hormonal activity in animals.") -AnnotationAssertion( "polypeptide hormone binding") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0017046") -AnnotationAssertion(rdfs:label "peptide hormone binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (purine nucleotide binding) - -AnnotationAssertion(Annotation( "GOC:ai") "Binding to a purine nucleotide, a compound consisting of a purine nucleoside esterified with (ortho)phosphate.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0017076") -AnnotationAssertion(rdfs:label "purine nucleotide binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (response to insecticide) - -AnnotationAssertion(Annotation( "GOC:curators") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insecticide stimulus. Insecticides are chemicals used to kill insects.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "insecticide resistance") -AnnotationAssertion( "insecticide susceptibility/resistance") -AnnotationAssertion( "GO:0017085") -AnnotationAssertion(rdfs:label "response to insecticide") -SubClassOf( ) - -# Class: (nucleologenesis) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0198506732") "A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a nucleolus, a small, dense body one or more of which are present in the nucleus of eukaryotic cells.") -AnnotationAssertion( "nucleolus biogenesis") -AnnotationAssertion(Annotation( "GOC:mah") "nucleolus assembly") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0017126") -AnnotationAssertion(rdfs:label "nucleologenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (stem cell division) - -AnnotationAssertion(Annotation( "GOC:jid") Annotation( "ISBN:0582227089") "The self-renewing division of a stem cell. A stem cell is an undifferentiated cell, in the embryo or adult, that can undergo unlimited division and give rise to one or several different cell types.") -AnnotationAssertion( ) -AnnotationAssertion( "stem cell renewal") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0017145") -AnnotationAssertion(rdfs:label "stem cell division") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) -DisjointClasses( ObjectSomeValuesFrom( )) - -# Class: (negative regulation of translation) - -AnnotationAssertion(Annotation( "GOC:isa_complete") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA.") -AnnotationAssertion( "GO:0016478") -AnnotationAssertion( "down regulation of protein biosynthetic process") -AnnotationAssertion( "down-regulation of protein biosynthetic process") -AnnotationAssertion( "downregulation of protein biosynthetic process") -AnnotationAssertion( "negative regulation of protein anabolism") -AnnotationAssertion( "negative regulation of protein biosynthesis") -AnnotationAssertion( "negative regulation of protein biosynthetic process") -AnnotationAssertion( "negative regulation of protein formation") -AnnotationAssertion( "negative regulation of protein synthesis") -AnnotationAssertion( "inhibition of protein biosynthetic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "protein biosynthesis inhibitor activity") -AnnotationAssertion( "protein biosynthetic process inhibitor activity") -AnnotationAssertion( "GO:0017148") -AnnotationAssertion(rdfs:label "negative regulation of translation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (regulation of exocytosis) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of exocytosis.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0017157") -AnnotationAssertion(rdfs:label "regulation of exocytosis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (peptidyl-tyrosine phosphorylation) - -AnnotationAssertion(Annotation( "RESID:AA0039") "The phosphorylation of peptidyl-tyrosine to form peptidyl-O4'-phospho-L-tyrosine.") -AnnotationAssertion( "RESID:AA0039") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0018108") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "peptidyl-tyrosine phosphorylation") -SubClassOf( ) -SubClassOf( ) - # Class: (heterocycle biosynthetic process) AnnotationAssertion(Annotation( "ISBN:0198547684") "The chemical reactions and pathways resulting in the formation of heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings).") @@ -65785,45 +23332,9 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0018130") AnnotationAssertion(rdfs:label "heterocycle biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) -# Class: (keratan sulfate biosynthetic process) - -AnnotationAssertion(Annotation( "ISBN:0198547684") Annotation( "RESID:AA0247") "The chemical reactions and pathways resulting in the formation of keratan sulfate, a glycosaminoglycan with repeat units consisting of beta-1,4-linked D-galactopyranosyl-beta-(1,4)-N-acetyl-D-glucosamine 6-sulfate and with variable amounts of fucose, sialic acid and mannose units; keratan sulfate chains are covalently linked by a glycosidic attachment through the trisaccharide galactosyl-galactosyl-xylose to peptidyl-threonine or serine residues.") -AnnotationAssertion( "RESID:AA0247") -AnnotationAssertion( "keratan sulfate anabolism") -AnnotationAssertion( "keratan sulfate biosynthesis") -AnnotationAssertion( "keratan sulfate formation") -AnnotationAssertion( "keratan sulfate synthesis") -AnnotationAssertion( "keratan sulphate biosynthesis") -AnnotationAssertion( "keratan sulphate biosynthetic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0018146") -AnnotationAssertion(rdfs:label "keratan sulfate biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (peptidyl-amino acid modification) - -AnnotationAssertion(Annotation( "GOC:mah") "The alteration of an amino acid residue in a peptide.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0018193") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "peptidyl-amino acid modification") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (peptidyl-tyrosine modification) - -AnnotationAssertion(Annotation( "GOC:go_curators") "The modification of peptidyl-tyrosine.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0018212") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "peptidyl-tyrosine modification") -SubClassOf( ) - # Class: (phenol-containing compound metabolic process) AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring.") @@ -65837,7 +23348,6 @@ AnnotationAssertion( "GO:0018958") AnnotationAssertion(rdfs:comment "Note that phenol metabolism is not included as a child of 'xenobiotic metabolism' because although it is synthesized industrially, phenol is also found naturally in animal wastes and other organic materials. It is often formed by the activity of microorganisms, which can chemically modify a variety of xenobiotic and naturally occurring phenolic compounds.") AnnotationAssertion(rdfs:label "phenol-containing compound metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ) @@ -65869,101 +23379,6 @@ AnnotationAssertion( "single-organism reproductive behavior") AnnotationAssertion( "GO:0019098") AnnotationAssertion(rdfs:label "reproductive behavior") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (transmembrane receptor protein kinase activity) - -AnnotationAssertion(Annotation( "GOC:mah") "Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: a protein + ATP = a phosphoprotein + ADP.") -AnnotationAssertion(Annotation(rdfs:label "STAT3 is phosphorylated by TSLP:IL7R:CRLF2:STAT3 complex") "Reactome:R-HSA-8983059") -AnnotationAssertion(Annotation(rdfs:label "JAK3 in IL7:p-Y449-IL7R:JAK1:IL2RG:JAK3 is phosphorylated") "Reactome:R-HSA-8983063") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0019199") -AnnotationAssertion(rdfs:label "transmembrane receptor protein kinase activity") -SubClassOf( ) -SubClassOf( ) - -# Class: (intermediate filament binding) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "Binding to an intermediate filament, a distinct elongated structure, characteristically 10 nm in diameter, that occurs in the cytoplasm of higher eukaryotic cells. Intermediate filaments form a fibrous system, composed of chemically heterogeneous subunits and involved in mechanically integrating the various components of the cytoplasmic space.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0019215") -AnnotationAssertion(rdfs:label "intermediate filament binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of lipid metabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving lipids.") -AnnotationAssertion( "regulation of lipid metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0019216") -AnnotationAssertion(rdfs:label "regulation of lipid metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of fatty acid metabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving fatty acids.") -AnnotationAssertion( "GO:0006632") -AnnotationAssertion( "regulation of fatty acid metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0019217") -AnnotationAssertion(rdfs:label "regulation of fatty acid metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of steroid metabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving steroids.") -AnnotationAssertion( "regulation of steroid metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0019218") -AnnotationAssertion(rdfs:label "regulation of steroid metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of nucleobase-containing compound metabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any cellular process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids.") -AnnotationAssertion( "regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process") -AnnotationAssertion( "GO:0019219") -AnnotationAssertion(rdfs:label "regulation of nucleobase-containing compound metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of phosphate metabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphates.") -AnnotationAssertion( "regulation of phosphate metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0019220") -AnnotationAssertion(rdfs:label "regulation of phosphate metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cytokine-mediated signaling pathway) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:signaling") Annotation( "PMID:19295629") "The series of molecular signals initiated by the binding of a cytokine to a receptor on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription.") -AnnotationAssertion( "cytokine and chemokine mediated signaling pathway") -AnnotationAssertion( "cytokine mediated signalling pathway") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0019221") -AnnotationAssertion(rdfs:label "cytokine-mediated signaling pathway") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (regulation of metabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.") -AnnotationAssertion( "GO:0044246") -AnnotationAssertion( "regulation of metabolism") -AnnotationAssertion( "regulation of multicellular organismal metabolic process") -AnnotationAssertion(Annotation( "GOC:tb") "regulation of organismal metabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0019222") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "regulation of metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (transmission of nerve impulse) @@ -65978,17 +23393,6 @@ SubClassOf( ObjectSomeValuesFrom( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (neuronal action potential) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:isa_complete") Annotation( "GOC:tb") "An action potential that occurs in a neuron.") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "generation of action potential") -AnnotationAssertion( "GO:0019228") -AnnotationAssertion(rdfs:label "neuronal action potential") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (proprioception) AnnotationAssertion(Annotation( "ISBN:072168677X") "The series of events by which an organism senses the position, location, orientation, and movement of the body and its parts. Proprioception is mediated by proprioceptors, sensory nerve terminals found in muscles, tendons, and joint capsules, which give information concerning movements and position of the body. The receptors in the labyrinth are sometimes also considered proprioceptors.") @@ -66019,162 +23423,6 @@ AnnotationAssertion( "response to pheromone") SubClassOf( ) -# Class: (D-ribose biosynthetic process) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of D-ribose, (ribo-pentose).") -AnnotationAssertion( "D-ribose anabolism") -AnnotationAssertion( "D-ribose biosynthesis") -AnnotationAssertion( "D-ribose formation") -AnnotationAssertion( "D-ribose synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0019302") -AnnotationAssertion(rdfs:label "D-ribose biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (D-ribose catabolic process) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of D-ribose (ribo-pentose).") -AnnotationAssertion( "MetaCyc:RIBOKIN-PWY") -AnnotationAssertion( "D-ribose breakdown") -AnnotationAssertion( "D-ribose catabolism") -AnnotationAssertion( "D-ribose degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0019303") -AnnotationAssertion(rdfs:label "D-ribose catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (hexose metabolic process) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving a hexose, any monosaccharide with a chain of six carbon atoms in the molecule.") -AnnotationAssertion( "hexose metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0019318") -AnnotationAssertion(rdfs:label "hexose metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (hexose biosynthetic process) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of hexose, any monosaccharide with a chain of six carbon atoms in the molecule.") -AnnotationAssertion( "hexose anabolism") -AnnotationAssertion( "hexose biosynthesis") -AnnotationAssertion( "hexose formation") -AnnotationAssertion( "hexose synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0019319") -AnnotationAssertion(rdfs:label "hexose biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (hexose catabolic process) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of hexose, any monosaccharide with a chain of six carbon atoms in the molecule.") -AnnotationAssertion( "hexose breakdown") -AnnotationAssertion( "hexose catabolism") -AnnotationAssertion( "hexose degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0019320") -AnnotationAssertion(rdfs:label "hexose catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (pentose metabolic process) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving a pentose, any monosaccharide with a chain of five carbon atoms in the molecule.") -AnnotationAssertion( "pentose metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0019321") -AnnotationAssertion(rdfs:label "pentose metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (pentose biosynthetic process) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of a pentose, any monosaccharide with a chain of five carbon atoms in the molecule.") -AnnotationAssertion( "pentose anabolism") -AnnotationAssertion( "pentose biosynthesis") -AnnotationAssertion( "pentose formation") -AnnotationAssertion( "pentose synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0019322") -AnnotationAssertion(rdfs:label "pentose biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (pentose catabolic process) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of a pentose, any monosaccharide with a chain of five carbon atoms in the molecule.") -AnnotationAssertion( "pentose breakdown") -AnnotationAssertion( "pentose catabolism") -AnnotationAssertion( "pentose degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0019323") -AnnotationAssertion(rdfs:label "pentose catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (phenol-containing compound catabolic process) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring.") -AnnotationAssertion( "MetaCyc:PHENOLDEG-PWY") -AnnotationAssertion( "phenol-containing compound breakdown") -AnnotationAssertion( "phenol-containing compound catabolism") -AnnotationAssertion( "phenol-containing compound degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0019336") -AnnotationAssertion(rdfs:label "phenol-containing compound catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (galactolipid metabolic process) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving galactolipids, any glycolipid containing one of more residues of galactose and/or N-acetylgalactosamine.") -AnnotationAssertion( "galactolipid metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0019374") -AnnotationAssertion(rdfs:label "galactolipid metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (galactolipid biosynthetic process) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of galactolipids, any glycolipid containing one of more residues of galactose and/or N-acetylgalactosamine.") -AnnotationAssertion( "galactolipid anabolism") -AnnotationAssertion( "galactolipid biosynthesis") -AnnotationAssertion( "galactolipid formation") -AnnotationAssertion( "galactolipid synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0019375") -AnnotationAssertion(rdfs:label "galactolipid biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (galactolipid catabolic process) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of galactolipids, any glycolipid containing one of more residues of galactose and/or N-acetylgalactosamine.") -AnnotationAssertion( "galactolipid breakdown") -AnnotationAssertion( "galactolipid catabolism") -AnnotationAssertion( "galactolipid degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0019376") -AnnotationAssertion(rdfs:label "galactolipid catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (glycolipid catabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways resulting in the breakdown of glycolipid, a class of 1,2-di-O-acylglycerols joined at oxygen 3 by a glycosidic linkage to a carbohydrate part (usually a mono-, di- or tri-saccharide).") -AnnotationAssertion( "glycolipid breakdown") -AnnotationAssertion( "glycolipid catabolism") -AnnotationAssertion( "glycolipid degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0019377") -AnnotationAssertion(rdfs:label "glycolipid catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (acetate biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways resulting in the formation of acetate, the anion of acetic acid.") -AnnotationAssertion( "acetate anabolism") -AnnotationAssertion( "acetate biosynthesis") -AnnotationAssertion( "acetate formation") -AnnotationAssertion( "acetate synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0019413") -AnnotationAssertion(rdfs:label "acetate biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (aromatic compound biosynthetic process) AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways resulting in the formation of aromatic compounds, any substance containing an aromatic carbon ring.") @@ -66187,35 +23435,9 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0019438") AnnotationAssertion(rdfs:label "aromatic compound biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) -# Class: (aromatic compound catabolic process) - -AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways resulting in the breakdown of aromatic compounds, any substance containing an aromatic carbon ring.") -AnnotationAssertion( "aromatic compound breakdown") -AnnotationAssertion( "aromatic compound catabolism") -AnnotationAssertion( "aromatic compound degradation") -AnnotationAssertion( "aromatic hydrocarbon catabolic process") -AnnotationAssertion( "aromatic hydrocarbon catabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0019439") -AnnotationAssertion(rdfs:label "aromatic compound catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (D-amino acid catabolic process) - -AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:jsg") "The chemical reactions and pathways resulting in the breakdown of D-amino acids, the D-enantiomers of amino acids.") -AnnotationAssertion( "D-amino acid breakdown") -AnnotationAssertion( "D-amino acid catabolism") -AnnotationAssertion( "D-amino acid degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0019478") -AnnotationAssertion(rdfs:label "D-amino acid catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (protein metabolic process) AnnotationAssertion(Annotation( "GOC:ma") "The chemical reactions and pathways involving a protein. Includes protein modification.") @@ -66238,107 +23460,8 @@ AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "protein metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (butyrate metabolic process) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving any butyrate, the anions of butyric acid (butanoic acid), a saturated, unbranched aliphatic acid.") -AnnotationAssertion( "GO:0043437") -AnnotationAssertion( "butanoic acid metabolic process") -AnnotationAssertion( "butanoic acid metabolism") -AnnotationAssertion( "butyrate metabolism") -AnnotationAssertion( "butyric acid metabolic process") -AnnotationAssertion( "butyric acid metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0019605") -AnnotationAssertion(rdfs:label "butyrate metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (catechol-containing compound catabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways resulting in the breakdown of catechol-containing compounds. Catechol is a compound containing a pyrocatechol nucleus or substituent.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "catechol breakdown") -AnnotationAssertion( "catechol catabolic process") -AnnotationAssertion( "catechol catabolism") -AnnotationAssertion( "catechol degradation") -AnnotationAssertion( "GO:0019614") -AnnotationAssertion(rdfs:label "catechol-containing compound catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (short-chain fatty acid catabolic process) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of a fatty acid with an aliphatic tail of less than 6 carbons.") -AnnotationAssertion( "MetaCyc:ACETOACETATE-DEG-PWY") -AnnotationAssertion( "short-chain fatty acid breakdown") -AnnotationAssertion( "short-chain fatty acid catabolism") -AnnotationAssertion( "short-chain fatty acid degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0019626") -AnnotationAssertion(rdfs:label "short-chain fatty acid catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (organophosphate metabolic process) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving organophosphates, any phosphate-containing organic compound.") -AnnotationAssertion( "organophosphate metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0019637") -AnnotationAssertion(rdfs:label "organophosphate metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (anaerobic purine nucleobase catabolic process) - -AnnotationAssertion(Annotation( "GOC:mah") "The anaerobic chemical reactions and pathways resulting in the breakdown of purine nucleobases, yielding energy in the form of ATP.") -AnnotationAssertion( "MetaCyc:P164-PWY") -AnnotationAssertion( "MetaCyc:PWY-5044") -AnnotationAssertion( "MetaCyc:PWY-5497") -AnnotationAssertion(Annotation( "GOC:go_curators") "anaerobic purine base catabolic process") -AnnotationAssertion( "anaerobic purine base catabolism") -AnnotationAssertion( "purine base fermentation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "anaerobic purine catabolic process") -AnnotationAssertion( "purine fermentation") -AnnotationAssertion( "GO:0019653") -AnnotationAssertion(rdfs:label "anaerobic purine nucleobase catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (acetate fermentation) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "MetaCyc:P142-PWY") "The anaerobic chemical reactions and pathways resulting in the breakdown of acetate, yielding energy in the form of ATP.") -AnnotationAssertion( ) -AnnotationAssertion( "MetaCyc:P142-PWY") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0019654") -AnnotationAssertion(rdfs:label "acetate fermentation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) -DisjointClasses( ObjectSomeValuesFrom( )) - -# Class: (nitrogenous compound fermentation) - -AnnotationAssertion(Annotation( "GOC:mah") "The anaerobic chemical reactions and pathways resulting in the breakdown of a nitrogen-containing compound, yielding energy in the form of ATP.") -AnnotationAssertion( "nitrogenous compound catabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0019666") -AnnotationAssertion(rdfs:label "nitrogenous compound fermentation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (ribose phosphate metabolic process) - -AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways involving ribose phosphate, any phosphorylated ribose sugar.") -AnnotationAssertion( "ribose phosphate metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0019693") -AnnotationAssertion(rdfs:label "ribose phosphate metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (choline metabolic process) AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0192801023") "The chemical reactions and pathways involving choline (2-hydroxyethyltrimethylammonium), an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine.") @@ -66346,38 +23469,8 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0019695") AnnotationAssertion(rdfs:label "choline metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (B cell mediated immunity) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GO_REF:0000022") Annotation( "ISBN:0781735149") "Any process involved with the carrying out of an immune response by a B cell, through, for instance, the production of antibodies or cytokines, or antigen presentation to T cells.") -AnnotationAssertion( "B lymphocyte mediated immune effector process") -AnnotationAssertion( "B lymphocyte mediated immunity") -AnnotationAssertion( "B-cell mediated immune effector process") -AnnotationAssertion( "B-cell mediated immunity") -AnnotationAssertion( "B-lymphocyte mediated immune effector process") -AnnotationAssertion( "B-lymphocyte mediated immunity") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0019724") -AnnotationAssertion(rdfs:label "B cell mediated immunity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (cellular homeostasis) - -AnnotationAssertion(Annotation( "GOC:isa_complete") Annotation( "GOC:jl") Annotation( "ISBN:0395825172") "Any process involved in the maintenance of an internal steady state at the level of the cell.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0019725") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "cellular homeostasis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) -DisjointClasses( ) - # Class: (antimicrobial humoral response) AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "GOC:mtg_sensu") "An immune response against microbes mediated through a body fluid. Examples of this process are seen in the antimicrobial humoral response of Drosophila melanogaster and Mus musculus.") @@ -66389,31 +23482,6 @@ AnnotationAssertion(rdfs:label "anti SubClassOf( ) SubClassOf( ) -# Class: (regulation of isoprenoid metabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving isoprenoids.") -AnnotationAssertion( "regulation of isoprenoid metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0019747") -AnnotationAssertion(rdfs:label "regulation of isoprenoid metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (secondary metabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways resulting in many of the chemical changes of compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon. In multicellular organisms secondary metabolism is generally carried out in specific cell types, and may be useful for the organism as a whole. In unicellular organisms, secondary metabolism is often used for the production of antibiotics or for the utilization and acquisition of unusual nutrients.") -AnnotationAssertion( "Wikipedia:Secondary_metabolism") -AnnotationAssertion( "secondary metabolism") -AnnotationAssertion( "secondary metabolite metabolic process") -AnnotationAssertion( "secondary metabolite metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0019748") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "secondary metabolic process") -SubClassOf( ) - # Class: (carboxylic acid metabolic process) AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving carboxylic acids, any organic acid containing one or more carboxyl (COOH) groups or anions (COO-).") @@ -66421,102 +23489,8 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0019752") AnnotationAssertion(rdfs:label "carboxylic acid metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (one-carbon compound transport) - -AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of one-carbon compounds into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion( "one carbon compound transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0019755") -AnnotationAssertion(rdfs:label "one-carbon compound transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (immunoglobulin complex) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:jl") Annotation( "ISBN:0781765196") "A protein complex that in its canonical form is composed of two identical immunoglobulin heavy chains and two identical immunoglobulin light chains, held together by disulfide bonds and sometimes complexed with additional proteins. An immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.") -AnnotationAssertion( "antibody") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0019814") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "Note that an immunoglobulin complex has the function of antigen binding if a suitable antigen is available.") -AnnotationAssertion(rdfs:label "immunoglobulin complex") -SubClassOf( ) - -# Class: (B cell receptor complex) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") "An immunoglobulin complex that is present in the plasma membrane of B cells and that in its canonical form is composed of two identical immunoglobulin heavy chains and two identical immunoglobulin light chains and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins.") -AnnotationAssertion( "GO:0042570") -AnnotationAssertion( "B lymphocyte receptor complex") -AnnotationAssertion( "B-cell receptor complex") -AnnotationAssertion( "B-lymphocyte receptor complex") -AnnotationAssertion( "BCR complex") -AnnotationAssertion( "immunoglobulin complex, membrane bound") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "B cell receptor accessory molecule complex") -AnnotationAssertion(Annotation( "GOC:mah") "antibody") -AnnotationAssertion( "GO:0019815") -AnnotationAssertion(rdfs:comment "Note that an immunoglobulin complex has the function of antigen binding if a suitable antigen is available.") -AnnotationAssertion(rdfs:label "B cell receptor complex") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (oxygen binding) - -AnnotationAssertion(Annotation( "GOC:jl") "Binding to oxygen (O2).") -AnnotationAssertion( "cytochrome P450") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "cytochrome P450 activity") -AnnotationAssertion( "GO:0019825") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "oxygen binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (stem cell population maintenance) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "ISBN:0878932437") "The process by which an organism or tissue maintains a population of stem cells of a single type. This can be achieved by a number of mechanisms: stem cell asymmetric division maintains stem cell numbers; stem cell symmetric division increases them; maintenance of a stem cell niche maintains the conditions for commitment to the stem cell fate for some types of stem cell; stem cells may arise de novo from other cell types.") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:vk") "maintenance of pluripotency") -AnnotationAssertion( "GO:0019827") -AnnotationAssertion(rdfs:label "stem cell population maintenance") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (isoprenoid binding) - -AnnotationAssertion(Annotation( "GOC:jl") "Binding to an isoprenoid compound, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0019840") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "isoprenoid binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (outer membrane) - -AnnotationAssertion(Annotation( "GOC:go_curators") "The external membrane of Gram-negative bacteria or certain organelles such as mitochondria and chloroplasts; freely permeable to most ions and metabolites.") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0019867") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "outer membrane") -SubClassOf( ) - -# Class: (antigen processing and presentation) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GO_REF:0000022") Annotation( "ISBN:0781735149") Annotation( "PMID:15771591") Annotation( "PMID:15928678") "The process in which an antigen-presenting cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.") -AnnotationAssertion( "GO:0030333") -AnnotationAssertion( "Wikipedia:Antigen_presentation") -AnnotationAssertion( "antigen presentation") -AnnotationAssertion( "antigen processing") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0019882") -AnnotationAssertion(rdfs:label "antigen processing and presentation") -SubClassOf( ) - # Class: (sexual reproduction) AnnotationAssertion(Annotation( "Wikipedia:Sexual_reproduction") "A type of reproduction that combines the genetic material of two gametes (such as a sperm or egg cell or fungal spores). The gametes have an haploid genome (with a single set of chromosomes, the product of a meiotic division) and combines with one another to produce a zygote (diploid).") @@ -66528,54 +23502,6 @@ AnnotationAssertion(rdfs:comment "No AnnotationAssertion(rdfs:label "sexual reproduction") SubClassOf( ) -# Class: (cytokine binding) - -AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:bf") Annotation( "ISBN:0198599471") "Binding to a cytokine, any of a group of proteins that function to control the survival, growth and differentiation of tissues and cells, and which have autocrine and paracrine activity.") -AnnotationAssertion( ) -AnnotationAssertion( "GO:0019965") -AnnotationAssertion( "IL binding") -AnnotationAssertion( "interleukin binding") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0019955") -AnnotationAssertion(rdfs:label "cytokine binding") -SubClassOf( ) -SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) -DisjointClasses( ObjectSomeValuesFrom( )) - -# Class: (prechordal plate formation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The formation of the prechordal plate. The prechordal plate is a thickening of the endoderm at the cranial end of the primitive streak formed by the involution of Spemann's organizer cells. The prechordal plate and the notochord induce the formation of the neural plate from the overlying ectodermal cells.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021501") -AnnotationAssertion(rdfs:label "prechordal plate formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (neural fold bending) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:15806586") "The morphogenesis of the neural fold elevations that results in the movement of the tips of the elevations towards each other in order to fuse.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021503") -AnnotationAssertion(rdfs:label "neural fold bending") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (neural fold hinge point formation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:13679871") Annotation( "PMID:15806586") "The formation of the median and lateral hinge points in the neural folds. These are created by apical constriction and basal expansion of the underlying neural cells. The median hinge point extends for the entire length of the neural tube, and the lateral hinge points do not form in the spinal cord region of the neural tube.") -AnnotationAssertion(Annotation( "GOC:cls") "neural fold furrowing") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021504") -AnnotationAssertion(rdfs:label "neural fold hinge point formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (anterior neuropore closure) AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The joining together of the neural folds of the rostral opening of the neural tube. The anterior neuropore appears before the process of neural tube closure is complete.") @@ -66585,1618 +23511,6 @@ AnnotationAssertion(rdfs:label "ante SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (floor plate formation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:11262869") "The formation of a ventral region of glial cells in the neural tube that provides inductive signals for the specification of neuronal cell types. The floor plate is evident at the ventral midline by the neural fold stage.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021508") -AnnotationAssertion(rdfs:label "floor plate formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (roof plate formation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:15936325") "The formation of a single row of glia at the dorsal midline of the developing neural tube. This region provides inductive signals for the specification of neuronal cell types and of the specification of neural crest cells. The cells comprising the roof plate are the precursors to radial glial cells.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021509") -AnnotationAssertion(rdfs:label "roof plate formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (spinal cord development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process whose specific outcome is the progression of the spinal cord over time, from its formation to the mature structure. The spinal cord primarily conducts sensory and motor nerve impulses between the brain and the peripheral nervous tissues.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021510") -AnnotationAssertion(rdfs:label "spinal cord development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (ventral spinal cord interneuron differentiation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:11262869") "The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of ventral spinal cord interneurons. Ventral spinal cord interneurons are cells located in the ventral portion of the spinal cord that transmit signals between sensory and motor neurons and are required for reflexive responses. Differentiation includes the processes involved in commitment of a cell to a specific fate.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021514") -AnnotationAssertion(rdfs:label "ventral spinal cord interneuron differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cell differentiation in spinal cord) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:11262869") "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the spinal cord. Differentiation includes the processes involved in commitment of a cell to a specific fate.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021515") -AnnotationAssertion(rdfs:label "cell differentiation in spinal cord") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (dorsal spinal cord development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:11179871") "The process whose specific outcome is the progression of the dorsal region of the spinal cord over time, from its formation to the mature structure. The dorsal region of the mature spinal cord contains neurons that process and relay sensory input.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021516") -AnnotationAssertion(rdfs:label "dorsal spinal cord development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (ventral spinal cord development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process whose specific outcome is the progression of the ventral region of the spinal cord over time, from its formation to the mature structure. The neurons of the ventral region of the mature spinal cord participate in motor output.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021517") -AnnotationAssertion(rdfs:label "ventral spinal cord development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (spinal cord motor neuron differentiation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:11262869") "The process in which neuroepithelial cells in the ventral neural tube acquire specialized structural and/or functional features of motor neurons. Motor neurons innervate an effector (muscle or glandular) tissue and are responsible for transmission of motor impulses from the brain to the periphery. Differentiation includes the processes involved in commitment of a cell to a specific fate.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021522") -AnnotationAssertion(rdfs:label "spinal cord motor neuron differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (somatic motor neuron differentiation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:11262869") "The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of somatic motor neurons. Somatic motor neurons innervate skeletal muscle targets and are responsible for transmission of motor impulses from the brain to the periphery. Differentiation includes the processes involved in commitment of a cell to a specific fate.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021523") -AnnotationAssertion(rdfs:label "somatic motor neuron differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (spinal cord radial glial cell differentiation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:16185248") "The process in which neuroepithelial cells in the ventral neural tube acquire specialized structural and/or functional features of radial glial cells. Radial cell precursors differentiate into both neuronal cell types and mature radial glial cells. Mature radial glial cells regulate the axon growth and pathfinding processes that occur during white matter patterning of the developing spinal cord. Differentiation includes the processes involved in commitment of a cell to a specific fate.") -AnnotationAssertion( "radial glial cell differentiation in spinal cord") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021531") -AnnotationAssertion(rdfs:label "spinal cord radial glial cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (neural tube patterning) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The regionalization process that regulates the coordinated growth that establishes the non-random spatial arrangement of the neural tube.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021532") -AnnotationAssertion(rdfs:label "neural tube patterning") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cell differentiation in hindbrain) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mature cells of the hindbrain. Differentiation includes the processes involved in commitment of a cell to a specific fate.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021533") -AnnotationAssertion(rdfs:label "cell differentiation in hindbrain") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - -# Class: (cell proliferation in hindbrain) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The multiplication or reproduction of cells, resulting in the expansion of a cell population in the hindbrain.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021534") -AnnotationAssertion(rdfs:label "cell proliferation in hindbrain") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - -# Class: (cell migration in hindbrain) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The orderly movement of a cell that will reside in the hindbrain.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021535") -AnnotationAssertion(rdfs:label "cell migration in hindbrain") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - -# Class: (diencephalon development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process whose specific outcome is the progression of the diencephalon over time, from its formation to the mature structure. The diencephalon is the paired caudal parts of the prosencephalon from which the thalamus, hypothalamus, epithalamus and subthalamus are derived; these regions regulate autonomic, visceral and endocrine function, and process information directed to the cerebral cortex.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021536") -AnnotationAssertion(rdfs:label "diencephalon development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (telencephalon development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:12626695") "The process whose specific outcome is the progression of the telencephalon over time, from its formation to the mature structure. The telencephalon is the paired anteriolateral division of the prosencephalon plus the lamina terminalis from which the olfactory lobes, cerebral cortex, and subcortical nuclei are derived.") -AnnotationAssertion(Annotation( "GOC:sl") Annotation( "PMID:22331407") "cerebrum development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021537") -AnnotationAssertion(rdfs:label "telencephalon development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (epithalamus development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The progression of the epithalamus over time from its initial formation until its mature state. The epithalamus is the small dorsomedial area of the thalamus including the habenular nuclei and associated fiber bundles, the pineal body, and the epithelial roof of the third ventricle.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021538") -AnnotationAssertion(rdfs:label "epithalamus development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (subthalamus development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process whose specific outcome is the progression of the subthalamus over time, from its formation to the mature structure. The subthalamus is the anterior part of the diencephalon that lies between the thalamus, hypothalamus, and tegmentum of the mesencephalon, including subthalamic nucleus, zona incerta, the fields of Forel, and the nucleus of ansa lenticularis.") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:cls") "ventral thalamus development") -AnnotationAssertion( "GO:0021539") -AnnotationAssertion(rdfs:label "subthalamus development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (corpus callosum morphogenesis) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process in which the anatomical structures of the corpus callosum are generated and organized. The corpus callosum is a thick bundle of nerve fibers comprising a commissural plate connecting the two cerebral hemispheres. It consists of contralateral axon projections that provides communications between the right and left cerebral hemispheres.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021540") -AnnotationAssertion(rdfs:label "corpus callosum morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (ammon gyrus development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process whose specific outcome is the progression of the ammon gyrus over time, from its formation to the mature structure. The ammon gyrus, often subdivided into the CA1 and CA3 regions, is one of the two interlocking gyri of the hippocampus that is rich in large pyramidal neurons.") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:cls") "Ammon's horn development") -AnnotationAssertion(Annotation( "GOC:cls") "cornu ammonis development") -AnnotationAssertion( "GO:0021541") -AnnotationAssertion(rdfs:label "ammon gyrus development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (dentate gyrus development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process whose specific outcome is the progression of the dentate gyrus over time, from its formation to the mature structure. The dentate gyrus is one of two interlocking gyri of the hippocampus. It contains granule cells, which project to the pyramidal cells and interneurons of the CA3 region of the ammon gyrus.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021542") -AnnotationAssertion(rdfs:label "dentate gyrus development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (pallium development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:12626695") "The process whose specific outcome is the progression of the pallium over time, from its formation to the mature structure. The pallium is the roof region of the telencephalon.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021543") -AnnotationAssertion(rdfs:label "pallium development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (subpallium development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:12626695") "The process whose specific outcome is the progression of the subpallium over time, from its formation to the mature structure. The subpallium is the base region of the telencephalon.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021544") -AnnotationAssertion(rdfs:label "subpallium development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cranial nerve development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process whose specific outcome is the progression of the cranial nerves over time, from its formation to the mature structure. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021545") -AnnotationAssertion(rdfs:label "cranial nerve development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (rhombomere development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process whose specific outcome is the progression of the rhombomere over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021546") -AnnotationAssertion(rdfs:label "rhombomere development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (midbrain-hindbrain boundary initiation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:isa_complete") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:15541513") "The regionalization process that gives rise to the midbrain-hindbrain boundary. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate.") -AnnotationAssertion(Annotation( "GOC:cls") "MHB biosynthesis") -AnnotationAssertion(Annotation( "GOC:cls") "MHB formation") -AnnotationAssertion(Annotation( "GOC:cls") "midbrain-hindbrain boundary biosynthesis") -AnnotationAssertion(Annotation( "GOC:cls") "midbrain-hindbrain boundary formation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:cls") "isthmus biosynthesis") -AnnotationAssertion(Annotation( "GOC:cls") "isthmus formation") -AnnotationAssertion( "GO:0021547") -AnnotationAssertion(rdfs:label "midbrain-hindbrain boundary initiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (pons development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process whose specific outcome is the progression of the pons over time, from its formation to the mature structure. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021548") -AnnotationAssertion(rdfs:label "pons development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cerebellum development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process whose specific outcome is the progression of the cerebellum over time, from its formation to the mature structure. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. In mice, the cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021549") -AnnotationAssertion(rdfs:label "cerebellum development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (medulla oblongata development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process whose specific outcome is the progression of the medulla oblongata over time, from its formation to the mature structure. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate.") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:cls") "medulla development") -AnnotationAssertion(Annotation( "GOC:cls") "myelencephalon development") -AnnotationAssertion( "GO:0021550") -AnnotationAssertion(rdfs:label "medulla oblongata development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (central nervous system morphogenesis) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0582227089") "The process in which the anatomical structure of the central nervous system is generated and organized. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021551") -AnnotationAssertion(rdfs:label "central nervous system morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (olfactory nerve development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process whose specific outcome is the progression of the olfactory nerve over time, from its formation to the mature structure. The olfactory nerve is a collection of sensory nerve rootlets that extend down from the olfactory bulb to the olfactory mucosa of the upper parts of the nasal cavity. This nerve conducts odor information to the brainstem.") -AnnotationAssertion(Annotation( "GOC:cls") "cranial nerve 1 development") -AnnotationAssertion(Annotation( "GOC:cls") "cranial nerve I development") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:cls") "CN 1 development") -AnnotationAssertion( "GO:0021553") -AnnotationAssertion(rdfs:label "olfactory nerve development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (optic nerve development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process whose specific outcome is the progression of the optic nerve over time, from its formation to the mature structure. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain.") -AnnotationAssertion(Annotation( "GOC:cls") "cranial nerve 2 development") -AnnotationAssertion(Annotation( "GOC:cls") "cranial nerve II development") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:cls") "CN II development") -AnnotationAssertion( "GO:0021554") -AnnotationAssertion(rdfs:label "optic nerve development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (midbrain-hindbrain boundary morphogenesis) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:15541513") "The process in which the anatomical structure of the midbrain-hindbrain boundary is generated and organized. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate.") -AnnotationAssertion(Annotation( "GOC:cls") "MHB morphogenesis") -AnnotationAssertion(Annotation( "GOC:cls") "isthmus morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021555") -AnnotationAssertion(rdfs:label "midbrain-hindbrain boundary morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (central nervous system formation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0582227089") "The process that gives rise to the central nervous system. This process pertains to the initial formation of a structure from unspecified parts. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain, spinal cord and spinal nerves. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021556") -AnnotationAssertion(rdfs:label "central nervous system formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (oculomotor nerve development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process whose specific outcome is the progression of the oculomotor nerve over time, from its formation to the mature structure. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle.") -AnnotationAssertion(Annotation( "GOC:cls") "cranial nerve 3 development") -AnnotationAssertion(Annotation( "GOC:cls") "cranial nerve III development") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:cls") "CN III development") -AnnotationAssertion( "GO:0021557") -AnnotationAssertion(rdfs:label "oculomotor nerve development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (trochlear nerve development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process whose specific outcome is the progression of the trochlear nerve over time, from its formation to the mature structure. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle.") -AnnotationAssertion(Annotation( "GOC:cls") "cranial nerve 4 development") -AnnotationAssertion(Annotation( "GOC:cls") "cranial nerve IV development") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:cls") "CN IV development") -AnnotationAssertion( "GO:0021558") -AnnotationAssertion(rdfs:label "trochlear nerve development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (trigeminal nerve development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process whose specific outcome is the progression of the trigeminal nerve over time, from its formation to the mature structure. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae.") -AnnotationAssertion(Annotation( "GOC:cls") "cranial nerve 5 development") -AnnotationAssertion(Annotation( "GOC:cls") "cranial nerve V development") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:cls") "CN V development") -AnnotationAssertion( "GO:0021559") -AnnotationAssertion(rdfs:label "trigeminal nerve development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (abducens nerve development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process whose specific outcome is the progression of the abducens nerve over time, from its formation to the mature structure. The motor function of the abducens nerve is to contract the lateral rectus which results in abduction of the eye.") -AnnotationAssertion(Annotation( "GOC:cls") "cranial nerve 6 development") -AnnotationAssertion(Annotation( "GOC:cls") "cranial nerve VI development") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:cls") "CN VI development") -AnnotationAssertion( "GO:0021560") -AnnotationAssertion(rdfs:label "abducens nerve development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (facial nerve development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process whose specific outcome is the progression of the facial nerve over time, from its formation to the mature structure. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial opthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives off nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities.") -AnnotationAssertion(Annotation( "GOC:cls") "cranial nerve 7 development") -AnnotationAssertion(Annotation( "GOC:cls") "cranial nerve VII development") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:cls") "CN VII development") -AnnotationAssertion( "GO:0021561") -AnnotationAssertion(rdfs:label "facial nerve development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (vestibulocochlear nerve development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process whose specific outcome is the progression of the vestibulocochlear nerve over time, from its formation to the mature structure. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea.") -AnnotationAssertion(Annotation( "GOC:cls") "CN VIII development") -AnnotationAssertion(Annotation( "PMID:11533729") "acoustic nerve development") -AnnotationAssertion(Annotation( "GOC:cls") "cranial nerve 8 development") -AnnotationAssertion(Annotation( "GOC:cls") "cranial nerve VIII development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021562") -AnnotationAssertion(rdfs:label "vestibulocochlear nerve development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (glossopharyngeal nerve development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion.") -AnnotationAssertion(Annotation( "GOC:cls") "cranial nerve 9 development") -AnnotationAssertion(Annotation( "GOC:cls") "cranial nerve IX development") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:cls") "CN IX development") -AnnotationAssertion( "GO:0021563") -AnnotationAssertion(rdfs:label "glossopharyngeal nerve development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (vagus nerve development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process whose specific outcome is the progression of the vagus nerve over time, from its formation to the mature structure. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis.") -AnnotationAssertion(Annotation( "GOC:cls") "cranial nerve X development") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:cls") "CN X development") -AnnotationAssertion(Annotation( "GOC:cls") "cranial nerve 10 development") -AnnotationAssertion( "GO:0021564") -AnnotationAssertion(rdfs:label "vagus nerve development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (accessory nerve development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process whose specific outcome is the progression of the accessory nerve over time, from its formation to the mature structure. In mice, the spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve.") -AnnotationAssertion(Annotation( "GOC:cls") "cranial nerve XI development") -AnnotationAssertion(Annotation( "PMID:11533729") "spinal accessory nerve development") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:cls") "CN XI development") -AnnotationAssertion(Annotation( "GOC:cls") "cranial nerve 11 development") -AnnotationAssertion( "GO:0021565") -AnnotationAssertion(rdfs:label "accessory nerve development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (hypoglossal nerve development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process whose specific outcome is the progression of the hypoglossal nerve over time, from its formation to the mature structure. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue.") -AnnotationAssertion(Annotation( "GOC:cls") "cranial nerve XII development") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:cls") "CN XII development") -AnnotationAssertion(Annotation( "GOC:cls") "cranial nerve 12 development") -AnnotationAssertion( "GO:0021566") -AnnotationAssertion(rdfs:label "hypoglossal nerve development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (rhombomere 1 development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process whose specific outcome is the progression of rhombomere 1 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021567") -AnnotationAssertion(rdfs:label "rhombomere 1 development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (rhombomere 2 development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process whose specific outcome is the progression of rhombomere 2 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021568") -AnnotationAssertion(rdfs:label "rhombomere 2 development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (rhombomere 3 development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process whose specific outcome is the progression of rhombomere 3 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021569") -AnnotationAssertion(rdfs:label "rhombomere 3 development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (rhombomere 4 development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process whose specific outcome is the progression of rhombomere 4 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021570") -AnnotationAssertion(rdfs:label "rhombomere 4 development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (rhombomere 5 development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process whose specific outcome is the progression of rhombomere 5 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021571") -AnnotationAssertion(rdfs:label "rhombomere 5 development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (rhombomere 6 development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process whose specific outcome is the progression of rhombomere 6 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021572") -AnnotationAssertion(rdfs:label "rhombomere 6 development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (rhombomere 7 development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process whose specific outcome is the progression of rhombomere 7 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021573") -AnnotationAssertion(rdfs:label "rhombomere 7 development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (rhombomere 8 development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process whose specific outcome is the progression of rhombomere 8 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021574") -AnnotationAssertion(rdfs:label "rhombomere 8 development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (hindbrain morphogenesis) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process in which the anatomical structure of the hindbrain is generated and organized. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "rhombencephalon morphogenesis") -AnnotationAssertion( "GO:0021575") -AnnotationAssertion(rdfs:label "hindbrain morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (hindbrain formation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process that gives rise to the hindbrain. This process pertains to the initial formation of a structure from unspecified parts. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021576") -AnnotationAssertion(rdfs:label "hindbrain formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (hindbrain maturation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "A developmental process, independent of morphogenetic (shape) change, that is required for the hindbrain to attain its fully functional state. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021578") -AnnotationAssertion(rdfs:label "hindbrain maturation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (medulla oblongata morphogenesis) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process in which the anatomical structure of the medulla oblongata is generated and organized. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "medulla morphogenesis") -AnnotationAssertion( "myelencephalon morphogenesis") -AnnotationAssertion( "GO:0021579") -AnnotationAssertion(rdfs:label "medulla oblongata morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (medulla oblongata formation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process that gives rise to the medulla oblongata. This process pertains to the initial formation of a structure from unspecified parts. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "medulla biosynthesis") -AnnotationAssertion( "medulla formation") -AnnotationAssertion( "myelencephalon biosynthesis") -AnnotationAssertion( "myelencephalon formation") -AnnotationAssertion( "GO:0021580") -AnnotationAssertion(rdfs:label "medulla oblongata formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (medulla oblongata maturation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "A developmental process, independent of morphogenetic (shape) change, that is required for the medulla oblongata to attain its fully functional state. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "medulla maturation") -AnnotationAssertion( "myelencephalon maturation") -AnnotationAssertion( "GO:0021582") -AnnotationAssertion(rdfs:label "medulla oblongata maturation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (pons morphogenesis) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process in which the anatomical structure of the pons is generated and organized. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021583") -AnnotationAssertion(rdfs:label "pons morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (pons formation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process that gives rise to the pons. This process pertains to the initial formation of a structure from unspecified parts. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021584") -AnnotationAssertion(rdfs:label "pons formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (pons maturation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "A developmental process, independent of morphogenetic (shape) change, that is required for the pons to attain its fully functional state. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021586") -AnnotationAssertion(rdfs:label "pons maturation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cerebellum morphogenesis) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process in which the anatomical structure of the cerebellum is generated and organized. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. The cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021587") -AnnotationAssertion(rdfs:label "cerebellum morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cerebellum formation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process that gives rise to the cerebellum. This process pertains to the initial formation of a structure from unspecified parts. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. The cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021588") -AnnotationAssertion(rdfs:label "cerebellum formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cerebellum maturation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellum to attain its fully functional state. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. The cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021590") -AnnotationAssertion(rdfs:label "cerebellum maturation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (ventricular system development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process whose specific outcome is the progression of the brain ventricular system over time, from its formation to the mature structure. The brain ventricular system consists of four communicating cavities within the brain that are continuous with the central canal of the spinal cord. These cavities include two lateral ventricles, the third ventricle and the fourth ventricle. Cerebrospinal fluid fills the ventricles and is produced by the choroid plexus.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021591") -AnnotationAssertion(rdfs:label "ventricular system development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (fourth ventricle development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process whose specific outcome is the progression of the fourth ventricle over time, from its formation to the mature structure. The fourth ventricle is an irregularly shaped cavity in the rhombencephalon, between the medulla oblongata, the pons, and the isthmus in front, and the cerebellum behind. It is continuous with the central canal of the cord below and with the cerebral aqueduct above, and through its lateral and median apertures it communicates with the subarachnoid space.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021592") -AnnotationAssertion(rdfs:label "fourth ventricle development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (rhombomere morphogenesis) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process in which the anatomical structure of the rhombomere is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021593") -AnnotationAssertion(rdfs:label "rhombomere morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (rhombomere formation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process that gives rise to the rhombomere. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021594") -AnnotationAssertion(rdfs:label "rhombomere formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (abducens nerve morphogenesis) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process in which the anatomical structure of the abducens nerve is generated and organized. The motor function of the abducens nerve is to contract the lateral rectus which results in abduction of the eye.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "CN VI development") -AnnotationAssertion( "GO:0021598") -AnnotationAssertion(rdfs:label "abducens nerve morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (abducens nerve formation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process that gives rise to the abducens nerve. This process pertains to the initial formation of a structure from unspecified parts. The motor function of the abducens nerve is to contract the lateral rectus which results in abduction of the eye.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "CN VI biosynthesis") -AnnotationAssertion( "CN VI formation") -AnnotationAssertion( "GO:0021599") -AnnotationAssertion(rdfs:label "abducens nerve formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (abducens nerve maturation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "A developmental process, independent of morphogenetic (shape) change, that is required for the abducens nerve to attain its fully functional state. The motor function of the abducens nerve is to contract the lateral rectus which results in abduction of the eye.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "CN VI maturation") -AnnotationAssertion( "GO:0021601") -AnnotationAssertion(rdfs:label "abducens nerve maturation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cranial nerve morphogenesis) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process in which the anatomical structure of the cranial nerves are generated and organized. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021602") -AnnotationAssertion(rdfs:label "cranial nerve morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cranial nerve formation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process that gives rise to the cranial nerves. This process pertains to the initial formation of a structure from unspecified parts. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021603") -AnnotationAssertion(rdfs:label "cranial nerve formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cranial nerve maturation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "A developmental process, independent of morphogenetic (shape) change, that is required for a cranial nerve to attain its fully functional state. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021605") -AnnotationAssertion(rdfs:label "cranial nerve maturation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (accessory nerve maturation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "A developmental process, independent of morphogenetic (shape) change, that is required for the accessory nerve to attain its fully functional state. The spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "CN XI maturation") -AnnotationAssertion( "spinal accessory nerve maturation") -AnnotationAssertion( "GO:0021606") -AnnotationAssertion(rdfs:label "accessory nerve maturation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (accessory nerve morphogenesis) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process in which the anatomical structure of the accessory nerve is generated and organized. The spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "CN XI morphogenesis") -AnnotationAssertion( "GO:0021607") -AnnotationAssertion(rdfs:label "accessory nerve morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (accessory nerve formation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process that gives rise to the accessory nerve. This process pertains to the initial formation of a structure from unspecified parts. The spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "CN XI biosynthesis") -AnnotationAssertion( "CN XI formation") -AnnotationAssertion( "GO:0021608") -AnnotationAssertion(rdfs:label "accessory nerve formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (facial nerve morphogenesis) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process in which the anatomical structure of the facial nerve is generated and organized. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial opthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives of nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "CN VII morphogenesis") -AnnotationAssertion( "GO:0021610") -AnnotationAssertion(rdfs:label "facial nerve morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (facial nerve formation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process that gives rise to the facial nerve. This process pertains to the initial formation of a structure from unspecified parts. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial opthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives of nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "CN VII biosynthesis") -AnnotationAssertion( "CN VII formation") -AnnotationAssertion( "GO:0021611") -AnnotationAssertion(rdfs:label "facial nerve formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (facial nerve maturation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "A developmental process, independent of morphogenetic (shape) change, that is required for the facial nerve to attain its fully functional state. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial opthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives of nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "CN VII maturation") -AnnotationAssertion( "GO:0021613") -AnnotationAssertion(rdfs:label "facial nerve maturation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (glossopharyngeal nerve maturation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "A developmental process, independent of morphogenetic (shape) change, that is required for the glossopharyngeal nerve to attain its fully functional state. Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "CN IX maturation") -AnnotationAssertion( "GO:0021614") -AnnotationAssertion(rdfs:label "glossopharyngeal nerve maturation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (glossopharyngeal nerve morphogenesis) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process in which the anatomical structure of the glossopharyngeal nerve is generated and organized. Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "CN IX morphogenesis") -AnnotationAssertion( "GO:0021615") -AnnotationAssertion(rdfs:label "glossopharyngeal nerve morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (glossopharyngeal nerve formation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process that gives rise to the glossopharyngeal nerve. This process pertains to the initial formation of a structure from unspecified parts. Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "CN IX biosynthesis") -AnnotationAssertion( "CN IX formation") -AnnotationAssertion( "GO:0021616") -AnnotationAssertion(rdfs:label "glossopharyngeal nerve formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (hypoglossal nerve morphogenesis) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process in which the anatomical structure of the hypoglossal nerve is generated and organized. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "CN XII morphogenesis") -AnnotationAssertion( "GO:0021618") -AnnotationAssertion(rdfs:label "hypoglossal nerve morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (hypoglossal nerve maturation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "A developmental process, independent of morphogenetic (shape) change, that is required for the hypoglossal nerve to attain its fully functional state. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "CN XII maturation") -AnnotationAssertion( "GO:0021619") -AnnotationAssertion(rdfs:label "hypoglossal nerve maturation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (hypoglossal nerve formation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process that gives rise to the hypoglossal nerve. This process pertains to the initial formation of a structure from unspecified parts. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "CN XII biosynthesis") -AnnotationAssertion( "CN XII formation") -AnnotationAssertion( "GO:0021620") -AnnotationAssertion(rdfs:label "hypoglossal nerve formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (oculomotor nerve morphogenesis) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process in which the anatomical structure of the oculomotor nerve is generated and organized. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "CN III morphogenesis") -AnnotationAssertion( "GO:0021622") -AnnotationAssertion(rdfs:label "oculomotor nerve morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (oculomotor nerve formation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process that gives rise to the oculomotor nerve. This process pertains to the initial formation of a structure from unspecified parts. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "CN III biosynthesis") -AnnotationAssertion( "CN III formation") -AnnotationAssertion( "GO:0021623") -AnnotationAssertion(rdfs:label "oculomotor nerve formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (oculomotor nerve maturation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "A developmental process, independent of morphogenetic (shape) change, that is required for the oculomotor nerve to attain its fully functional state. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "CN III maturation") -AnnotationAssertion( "GO:0021625") -AnnotationAssertion(rdfs:label "oculomotor nerve maturation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (central nervous system maturation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0582227089") "A developmental process, independent of morphogenetic (shape) change, that is required for the central nervous system to attain its fully functional state. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021626") -AnnotationAssertion(rdfs:label "central nervous system maturation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (olfactory nerve morphogenesis) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process in which the anatomical structure of the olfactory nerve is generated and organized. The olfactory nerve is a collection of sensory nerve rootlets that extend down from the olfactory bulb to the olfactory mucosa of the upper parts of the nasal cavity. This nerve conducts odor information to the brainstem.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "CN I morphogenesis") -AnnotationAssertion( "GO:0021627") -AnnotationAssertion(rdfs:label "olfactory nerve morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (olfactory nerve formation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process that gives rise to the olfactory nerve. This process pertains to the initial formation of a structure from unspecified parts. The olfactory nerve is a collection of sensory nerve rootlets that extend down from the olfactory bulb to the olfactory mucosa of the upper parts of the nasal cavity. This nerve conducts odor information to the brainstem.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "CN I biosynthesis") -AnnotationAssertion( "CN I formation") -AnnotationAssertion( "GO:0021628") -AnnotationAssertion(rdfs:label "olfactory nerve formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (olfactory nerve maturation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "A developmental process, independent of morphogenetic (shape) change, that is required for the olfactory nerve to attain its fully functional state. The olfactory nerve is a collection of sensory nerve rootlets that extend down from the olfactory bulb to the olfactory mucosa of the upper parts of the nasal cavity. This nerve conducts odor information to the brainstem.") -AnnotationAssertion( "CN I maturation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021630") -AnnotationAssertion(rdfs:label "olfactory nerve maturation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (optic nerve morphogenesis) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process in which the anatomical structure of the optic nerve is generated and organized. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "CN II morphogenesis") -AnnotationAssertion( "GO:0021631") -AnnotationAssertion(rdfs:label "optic nerve morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (optic nerve maturation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "A developmental process, independent of morphogenetic (shape) change, that is required for the optic nerve to attain its fully functional state. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain.") -AnnotationAssertion( "CN II maturation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021632") -AnnotationAssertion(rdfs:label "optic nerve maturation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (optic nerve formation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process that gives rise to the optic nerve. This process pertains to the initial formation of a structure from unspecified parts. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "CN II biosynthesis") -AnnotationAssertion( "CN II formation") -AnnotationAssertion( "GO:0021634") -AnnotationAssertion(rdfs:label "optic nerve formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (trigeminal nerve maturation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "A developmental process, independent of morphogenetic (shape) change, that is required for the trigeminal nerve to attain its fully functional state. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "CN V maturation") -AnnotationAssertion( "GO:0021635") -AnnotationAssertion(rdfs:label "trigeminal nerve maturation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (trigeminal nerve morphogenesis) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process in which the anatomical structure of the trigeminal nerve is generated and organized. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "CN V morphogenesis") -AnnotationAssertion( "GO:0021636") -AnnotationAssertion(rdfs:label "trigeminal nerve morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (trigeminal nerve formation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process that gives rise to the trigeminal nerve. This process pertains to the initial formation of a structure from unspecified parts. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "CN V biosynthesis") -AnnotationAssertion( "CN V formation") -AnnotationAssertion( "GO:0021638") -AnnotationAssertion(rdfs:label "trigeminal nerve formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (trochlear nerve morphogenesis) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process in which the anatomical structure of the trochlear nerve is generated and organized. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "CH IV morphogenesis") -AnnotationAssertion( "GO:0021639") -AnnotationAssertion(rdfs:label "trochlear nerve morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (trochlear nerve maturation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "A developmental process, independent of morphogenetic (shape) change, that is required for the trochlear nerve to attain its fully functional state. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "CN IV maturation") -AnnotationAssertion( "GO:0021640") -AnnotationAssertion(rdfs:label "trochlear nerve maturation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (trochlear nerve formation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process that gives rise to the trochlear nerve. This process pertains to the initial formation of a structure from unspecified parts. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "CN IV biosynthesis") -AnnotationAssertion( "CN IV formation") -AnnotationAssertion( "GO:0021642") -AnnotationAssertion(rdfs:label "trochlear nerve formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (vagus nerve maturation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "A developmental process, independent of morphogenetic (shape) change, that is required for the vagus nerve to attain its fully functional state. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "CN X maturation") -AnnotationAssertion( "GO:0021643") -AnnotationAssertion(rdfs:label "vagus nerve maturation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (vagus nerve morphogenesis) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process in which the anatomical structure of the vagus nerve is generated and organized. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "CN X morphogenesis") -AnnotationAssertion( "GO:0021644") -AnnotationAssertion(rdfs:label "vagus nerve morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (vagus nerve formation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process that gives rise to the vagus nerve. This process pertains to the initial formation of a structure from unspecified parts. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "CN X biosynthesis") -AnnotationAssertion( "CN X formation") -AnnotationAssertion( "GO:0021646") -AnnotationAssertion(rdfs:label "vagus nerve formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (vestibulocochlear nerve maturation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "A developmental process, independent of morphogenetic (shape) change, that is required for the vestibulocochlear nerve to attain its fully functional state. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "CN VIII maturation") -AnnotationAssertion( "auditory nerve maturation") -AnnotationAssertion( "GO:0021647") -AnnotationAssertion(rdfs:label "vestibulocochlear nerve maturation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (vestibulocochlear nerve morphogenesis) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process in which the anatomical structure of the vestibulocochlear nerve is generated and organized. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "CN VIII morphogenesis") -AnnotationAssertion( "GO:0021648") -AnnotationAssertion(rdfs:label "vestibulocochlear nerve morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (vestibulocochlear nerve formation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process that gives rise to the vestibulocochlear nerve. This process pertains to the initial formation of a structure from unspecified parts. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "CN VII formation") -AnnotationAssertion( "GO:0021650") -AnnotationAssertion(rdfs:label "vestibulocochlear nerve formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (rhombomere 1 morphogenesis) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process in which the anatomical structure of rhombomere 1 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021651") -AnnotationAssertion(rdfs:label "rhombomere 1 morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (rhombomere 1 formation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process that gives rise to rhombomere 1. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021652") -AnnotationAssertion(rdfs:label "rhombomere 1 formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (rhombomere boundary formation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process that gives rise to a rhombomere boundary. This process pertains to the initial formation of a boundary delimiting a rhombomere. Rhombomeres are transverse segments of the developing rhombencephalon that are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021654") -AnnotationAssertion(rdfs:label "rhombomere boundary formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (rhombomere 2 morphogenesis) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process in which the anatomical structure of rhombomere 2 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021655") -AnnotationAssertion(rdfs:label "rhombomere 2 morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (rhombomere 2 formation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process that gives rise to rhombomere 2. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021657") -AnnotationAssertion(rdfs:label "rhombomere 2 formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (rhombomere 3 morphogenesis) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process in which the anatomical structure of rhombomere 3 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021658") -AnnotationAssertion(rdfs:label "rhombomere 3 morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (rhombomere 3 formation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process that gives rise to rhombomere 3. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021660") -AnnotationAssertion(rdfs:label "rhombomere 3 formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (rhombomere 4 morphogenesis) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process in which the anatomical structure of rhombomere 4 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021661") -AnnotationAssertion(rdfs:label "rhombomere 4 morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (rhombomere 4 formation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process that gives rise to rhombomere 4. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021663") -AnnotationAssertion(rdfs:label "rhombomere 4 formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (rhombomere 5 morphogenesis) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process in which the anatomical structures of rhombomere 5 are generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021664") -AnnotationAssertion(rdfs:label "rhombomere 5 morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (rhombomere 5 formation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process that gives rise to rhombomere 5. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021666") -AnnotationAssertion(rdfs:label "rhombomere 5 formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (rhombomere 6 morphogenesis) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process in which the anatomical structure of rhombomere 6 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021667") -AnnotationAssertion(rdfs:label "rhombomere 6 morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (rhombomere 6 formation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process that gives rise to rhombomere 6. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021669") -AnnotationAssertion(rdfs:label "rhombomere 6 formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (lateral ventricle development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process whose specific outcome is the progression of the lateral ventricles over time, from the formation to the mature structure. The two lateral ventricles are a cavity in each of the cerebral hemispheres derived from the cavity of the embryonic neural tube. They are separated from each other by the septum pellucidum, and each communicates with the third ventricle by the foramen of Monro, through which also the choroid plexuses of the lateral ventricles become continuous with that of the third ventricle.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021670") -AnnotationAssertion(rdfs:label "lateral ventricle development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (rhombomere 7 morphogenesis) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process in which the anatomical structure of rhombomere 7 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021671") -AnnotationAssertion(rdfs:label "rhombomere 7 morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (rhombomere 7 formation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process that gives rise to rhombomere 7. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021673") -AnnotationAssertion(rdfs:label "rhombomere 7 formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (rhombomere 8 morphogenesis) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process in which the anatomical structure of rhombomere 8 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021674") -AnnotationAssertion(rdfs:label "rhombomere 8 morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (nerve development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process whose specific outcome is the progression of a nerve over time, from its formation to the mature structure.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021675") -AnnotationAssertion(rdfs:label "nerve development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (rhombomere 8 formation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process that gives rise to rhombomere 8. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021677") -AnnotationAssertion(rdfs:label "rhombomere 8 formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (third ventricle development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process whose specific outcome is the progression of the third ventricle over time, from its formation to the mature structure. The third ventricle is the narrow cleft inferior to the corpus callosum, within the diencephalon, between the paired thalami. Its floor is formed by the hypothalamus, its anterior wall by the lamina terminalis, and its roof by ependyma, and it communicates with the fourth ventricle by the cerebral aqueduct, and with the lateral ventricles by the interventricular foramina.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021678") -AnnotationAssertion(rdfs:label "third ventricle development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cerebellar molecular layer development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process whose specific outcome is the progression of the cerebellar molecular layer nerve over time, from its formation to the mature structure. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021679") -AnnotationAssertion(rdfs:label "cerebellar molecular layer development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cerebellar Purkinje cell layer development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process whose specific outcome is the progression of the cerebellar Purkinje cell layer over time, from its formation to the mature structure. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021680") -AnnotationAssertion(rdfs:label "cerebellar Purkinje cell layer development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cerebellar granular layer development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process whose specific outcome is the progression of the cerebellar granule layer over time, from its formation to the mature structure. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021681") -AnnotationAssertion(rdfs:label "cerebellar granular layer development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (nerve maturation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "A developmental process, independent of morphogenetic (shape) change, that is required for a nerve to attain its fully functional state.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021682") -AnnotationAssertion(rdfs:label "nerve maturation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cerebellar granular layer morphogenesis) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process in which the anatomical structure of the cerebellar granular layer is generated and organized. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021683") -AnnotationAssertion(rdfs:label "cerebellar granular layer morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cerebellar granular layer formation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process that gives rise to the cerebellar granule layer. This process pertains to the initial formation of a structure from unspecified parts. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021684") -AnnotationAssertion(rdfs:label "cerebellar granular layer formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cerebellar granular layer maturation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellar granular layer to attain its fully functional state. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021686") -AnnotationAssertion(rdfs:label "cerebellar granular layer maturation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cerebellar molecular layer morphogenesis) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process in which the anatomical structure of the cerebellar molecular layer is generated and organized. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021687") -AnnotationAssertion(rdfs:label "cerebellar molecular layer morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cerebellar molecular layer formation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process that gives rise to the cerebellar molecular layer. This process pertains to the initial formation of a structure from unspecified parts. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021688") -AnnotationAssertion(rdfs:label "cerebellar molecular layer formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cerebellar molecular layer maturation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellar molecular layer to attain its fully functional state. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021690") -AnnotationAssertion(rdfs:label "cerebellar molecular layer maturation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cerebellar Purkinje cell layer maturation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellar Purkinje cell layer to attain its fully functional state. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021691") -AnnotationAssertion(rdfs:label "cerebellar Purkinje cell layer maturation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cerebellar Purkinje cell layer morphogenesis) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process in which the anatomical structure of the cerebellar Purkinje cell layer is generated and organized. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021692") -AnnotationAssertion(rdfs:label "cerebellar Purkinje cell layer morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cerebellar Purkinje cell layer formation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process that gives rise to the cerebellar Purkinje cell layer. This process pertains to the initial formation of a structure from unspecified parts. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021694") -AnnotationAssertion(rdfs:label "cerebellar Purkinje cell layer formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cerebellar cortex development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process whose specific outcome is the progression of the cerebellar cortex over time, from its formation to the mature structure. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021695") -AnnotationAssertion(rdfs:label "cerebellar cortex development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cerebellar cortex morphogenesis) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process in which the anatomical structure of the cranial nerves are generated and organized. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021696") -AnnotationAssertion(rdfs:label "cerebellar cortex morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cerebellar cortex formation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process that gives rise to the cerebellar cortex. This process pertains to the initial formation of a structure from unspecified parts. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021697") -AnnotationAssertion(rdfs:label "cerebellar cortex formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cerebellar cortex maturation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellar cortex to attain its fully functional state. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021699") -AnnotationAssertion(rdfs:label "cerebellar cortex maturation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (developmental maturation) AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "A developmental process, independent of morphogenetic (shape) change, that is required for an anatomical structure, cell or cellular component to attain its fully functional state.") @@ -68206,1085 +23520,12 @@ AnnotationAssertion( "developmental maturation") SubClassOf( ) -# Class: (cerebellar Golgi cell differentiation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:15157725") "The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar Golgi cell. Differentiation includes the processes involved in commitment of a neuroblast to a Golgi cell fate. A cerebellar Golgi cell is an inhibitory GABAergic interneuron found in the cerebellar cortex.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021701") -AnnotationAssertion(rdfs:label "cerebellar Golgi cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cerebellar Purkinje cell differentiation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:15157725") "The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar Purkinje cell. Differentiation includes the processes involved in commitment of a neuroblast to a Purkinje cell fate. A Purkinje cell is an inhibitory GABAergic neuron found in the cerebellar cortex that projects to the deep cerebellar nuclei and brain stem.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021702") -AnnotationAssertion(rdfs:label "cerebellar Purkinje cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (locus ceruleus development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process whose specific outcome is the progression of the locus ceruleus over time, from its formation to the mature structure. The locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic.") -AnnotationAssertion( "locus caeruleus development") -AnnotationAssertion( "locus coeruleus development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021703") -AnnotationAssertion(rdfs:label "locus ceruleus development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (locus ceruleus morphogenesis) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process in which the anatomical structure of the locus ceruleus is generated and organized. In mice, the locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021704") -AnnotationAssertion(rdfs:label "locus ceruleus morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (locus ceruleus formation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process that gives rise to the locus ceruleus. This process pertains to the initial formation of a structure from unspecified parts. In mice, the locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021705") -AnnotationAssertion(rdfs:label "locus ceruleus formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (locus ceruleus maturation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "A developmental process, independent of morphogenetic (shape) change, that is required for the locus ceruleus to attain its fully functional state. The locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021706") -AnnotationAssertion(rdfs:label "locus ceruleus maturation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cerebellar granule cell differentiation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:15157725") "The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar granule cell. Differentiation includes the processes involved in commitment of a neuroblast to a granule cell fate. A granule cell is a glutamatergic interneuron found in the cerebellar cortex.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021707") -AnnotationAssertion(rdfs:label "cerebellar granule cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cerebellar stellate cell differentiation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:15157725") "The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar stellate cell. Differentiation includes the processes involved in commitment of a neuroblast to a cerebellar stellate cell fate. A cerebellar stellate cell is an inhibitory GABAergic interneuron found in the cerebellar cortex.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021710") -AnnotationAssertion(rdfs:label "cerebellar stellate cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (inferior olivary nucleus development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process whose specific outcome is the progression of the inferior olivary nucleus over time, from its formation to the mature structure. The inferior olivary nucleus is a capsule-shaped structure in the ventral medulla located just lateral and dorsal to the medullary pyramids. Neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex; these neurons have been implicated in various functions, such as learning and timing of movements.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "inferior olive development") -AnnotationAssertion( "GO:0021713") -AnnotationAssertion(rdfs:label "inferior olivary nucleus development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (inferior olivary nucleus morphogenesis) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process in which the anatomical structure of the inferior olivary nucleus is generated and organized. The inferior olivary nucleus is a capsule-shaped structure in the ventral medulla located just lateral and dorsal to the medullary pyramids. Neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex; these neurons have been implicated in various functions, such as learning and timing of movements.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "inferior olive morphogenesis") -AnnotationAssertion( "GO:0021714") -AnnotationAssertion(rdfs:label "inferior olivary nucleus morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (inferior olivary nucleus formation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process that gives rise to the inferior olivary nucleus. This process pertains to the initial formation of a structure from unspecified parts. The inferior olivary nucleus is a capsule-shaped structure in the ventral medulla located just lateral and dorsal to the medullary pyramids. Neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex; these neurons have been implicated in various functions, such as learning and timing of movements.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "inferior olive biosynthesis") -AnnotationAssertion( "inferior olive formation") -AnnotationAssertion( "GO:0021715") -AnnotationAssertion(rdfs:label "inferior olivary nucleus formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (inferior olivary nucleus maturation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "A developmental process, independent of morphogenetic (shape) change, that is required for the inferior olivary nucleus to attain its fully functional state. The inferior olivary nucleus is a capsule-shaped structure in the ventral medulla located just lateral and dorsal to the medullary pyramids. Neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex; these neurons have been implicated in various functions, such as learning and timing of movements.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "inferior olive maturation") -AnnotationAssertion( "GO:0021717") -AnnotationAssertion(rdfs:label "inferior olivary nucleus maturation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (superior olivary nucleus development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process whose specific outcome is the progression of the superior olivary nucleus over time, from its formation to the mature structure. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "superior olive development") -AnnotationAssertion( "GO:0021718") -AnnotationAssertion(rdfs:label "superior olivary nucleus development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (superior olivary nucleus morphogenesis) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process in which the anatomical structure of the superior olivary nucleus is generated and organized. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "superior olive morphogenesis") -AnnotationAssertion( "GO:0021719") -AnnotationAssertion(rdfs:label "superior olivary nucleus morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (superior olivary nucleus formation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process that gives rise to the superior olivary nucleus. This process pertains to the initial formation of a structure from unspecified parts. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021720") -AnnotationAssertion(rdfs:label "superior olivary nucleus formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (superior olivary nucleus maturation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "A developmental process, independent of morphogenetic (shape) change, that is required for the superior olivary nucleus to attain its fully functional state. The superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "superior olive maturation") -AnnotationAssertion( "GO:0021722") -AnnotationAssertion(rdfs:label "superior olivary nucleus maturation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (medullary reticular formation development) - -AnnotationAssertion(Annotation( "GOC:cjm") Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "Wikipedia:Rhombencephalon") Annotation( "http://www.brainspan.org") "The process whose specific outcome is the progression of the medullary reticular formation over time, from its formation to the mature structure. The medullary reticular formation is a series of brain nuclei located in the medulla oblongata.") -AnnotationAssertion( "rhombencephalic reticular formation development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021723") -AnnotationAssertion(rdfs:label "medullary reticular formation development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (inferior raphe nucleus development) - -AnnotationAssertion(Annotation( "GOC:cjm") Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:cvs") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:19003874") Annotation( "ZFA:0000366") "The process whose specific outcome is the progression of the inferior raphe nucleus over time, from its formation to the mature structure.") -AnnotationAssertion( "inferior central nucleus development") -AnnotationAssertion( "posterior raphe nucleus development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021724") -AnnotationAssertion(rdfs:label "inferior raphe nucleus development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - -# Class: (superior raphe nucleus development) - -AnnotationAssertion(Annotation( "GOC:cjm") Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:cvs") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:19003874") Annotation( "ZFA:0000440") "The process whose specific outcome is the progression of the superior raphe nucleus over time, from its formation to the mature structure.") -AnnotationAssertion( "anterior raphe nucleus development") -AnnotationAssertion( "superior central nucleus development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021725") -AnnotationAssertion(rdfs:label "superior raphe nucleus development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - -# Class: (lateral reticular nucleus development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process whose specific outcome is the progression of the lateral reticular nucleus over time, from its formation to the mature structure.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021726") -AnnotationAssertion(rdfs:label "lateral reticular nucleus development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (intermediate reticular formation development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process whose specific outcome is the progression of the intermediate reticular formation over time, from its formation to the mature structure.") -AnnotationAssertion(Annotation( "http://www.brainspan.org") "intermediate reticular nucleus development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021727") -AnnotationAssertion(rdfs:label "intermediate reticular formation development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (inferior reticular formation development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process whose specific outcome is the progression of the inferior reticular formation over time, from its formation to the mature structure.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021728") -AnnotationAssertion(rdfs:label "inferior reticular formation development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (superior reticular formation development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process whose specific outcome is the progression of the superior reticular formation over time, from its formation to the mature structure.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021729") -AnnotationAssertion(rdfs:label "superior reticular formation development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (trigeminal sensory nucleus development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process whose specific outcome is the progression of the trigeminal sensory nucleus over time, from its formation to the mature structure.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021730") -AnnotationAssertion(rdfs:comment "Note that this term was placed as a child of 'brain development' because the nucleus spans multiple brain regions from midbrain to spinal cord.") -AnnotationAssertion(rdfs:label "trigeminal sensory nucleus development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (trigeminal motor nucleus development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process whose specific outcome is the progression of the trigeminal motor nucleus over time, from its formation to the mature structure.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021731") -AnnotationAssertion(rdfs:label "trigeminal motor nucleus development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (midbrain-hindbrain boundary maturation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:15541513") "A developmental process, independent of morphogenetic (shape) change, that is required for the midbrain-hindbrain boundary to attain its fully functional state. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "MHB maturation") -AnnotationAssertion( "isthmus maturation") -AnnotationAssertion( "GO:0021732") -AnnotationAssertion(rdfs:label "midbrain-hindbrain boundary maturation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (dentate nucleus development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process whose specific outcome is the progression of the dentate nucleus over time, from its formation to the mature structure.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021735") -AnnotationAssertion(rdfs:label "dentate nucleus development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (globose nucleus development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process whose specific outcome is the progression of the globose nucleus over time, from its formation to the mature structure.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021736") -AnnotationAssertion(rdfs:label "globose nucleus development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (emboliform nucleus development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process whose specific outcome is the progression of the emboliform nucleus over time, from its formation to the mature structure.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021737") -AnnotationAssertion(rdfs:label "emboliform nucleus development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (fastigial nucleus development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process whose specific outcome is the progression of the fastigial nucleus over time, from its formation to the mature structure.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021738") -AnnotationAssertion(rdfs:label "fastigial nucleus development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (mesencephalic trigeminal nucleus development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process whose specific outcome is the progression of the mesencephalic trigeminal nucleus over time, from its formation to the mature structure.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021739") -AnnotationAssertion(rdfs:label "mesencephalic trigeminal nucleus development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (principal sensory nucleus of trigeminal nerve development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process whose specific outcome is the progression of the pontine nucleus over time, from its formation to the mature structure.") -AnnotationAssertion(Annotation( "GOC:dph") "pontine nucleus development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021740") -AnnotationAssertion(rdfs:comment "Note that this term was placed as a child of 'brain development' because the nucleus spans multiple brain regions.") -AnnotationAssertion(rdfs:label "principal sensory nucleus of trigeminal nerve development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (spinal trigeminal nucleus development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process whose specific outcome is the progression of the spinal trigeminal nucleus over time, from its formation to the mature structure.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021741") -AnnotationAssertion(rdfs:label "spinal trigeminal nucleus development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (abducens nucleus development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process whose specific outcome is the progression of the abducens nucleus over time, from its formation to the mature structure.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021742") -AnnotationAssertion(rdfs:label "abducens nucleus development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (hypoglossal nucleus development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process whose specific outcome is the progression of the hypoglossal nucleus over time, from its formation to the mature structure.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021743") -AnnotationAssertion(rdfs:label "hypoglossal nucleus development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (dorsal motor nucleus of vagus nerve development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process whose specific outcome is the progression of the dorsal motor nucleus of the vagus nerve over time, from its formation to the mature structure.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021744") -AnnotationAssertion(rdfs:label "dorsal motor nucleus of vagus nerve development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (nucleus ambiguus development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process whose specific outcome is the progression of the nucleus ambiguus over time, from its formation to the mature structure.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021745") -AnnotationAssertion(rdfs:label "nucleus ambiguus development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (solitary nucleus development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process whose specific outcome is the progression of the solitary nucleus over time, from its formation to the mature structure.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021746") -AnnotationAssertion(rdfs:label "solitary nucleus development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cochlear nucleus development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process whose specific outcome is the progression of the cochlear nucleus over time, from its formation to the mature structure.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021747") -AnnotationAssertion(rdfs:label "cochlear nucleus development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (dorsal cochlear nucleus development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process whose specific outcome is the progression of the dorsal cochlear nucleus over time, from its formation to the mature structure.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021748") -AnnotationAssertion(rdfs:label "dorsal cochlear nucleus development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (ventral cochlear nucleus development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process whose specific outcome is the progression of the ventral cochlear nucleus over time, from its formation to the mature structure.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021749") -AnnotationAssertion(rdfs:label "ventral cochlear nucleus development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (vestibular nucleus development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:16221589") "The process whose specific outcome is the progression of the vestibular nucleus over time, from its formation to the mature structure.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021750") -AnnotationAssertion(rdfs:label "vestibular nucleus development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (salivary nucleus development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process whose specific outcome is the progression of a salivary nucleus over time, from its formation to the mature structure.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021751") -AnnotationAssertion(rdfs:label "salivary nucleus development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (inferior salivary nucleus development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process whose specific outcome is the progression of the inferior salivary nucleus over time, from its formation to the mature structure.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021752") -AnnotationAssertion(rdfs:label "inferior salivary nucleus development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (superior salivary nucleus development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process whose specific outcome is the progression of the superior salivary nucleus over time, from its formation to the mature structure.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021753") -AnnotationAssertion(rdfs:label "superior salivary nucleus development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (facial nucleus development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process whose specific outcome is the progression of the facial nucleus over time, from its formation to the mature structure.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021754") -AnnotationAssertion(rdfs:label "facial nucleus development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (striatum development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0878937420") "The progression of the striatum over time from its initial formation until its mature state. The striatum is a region of the forebrain consisting of the caudate nucleus, putamen and fundus striati.") -AnnotationAssertion( "neostriatum development") -AnnotationAssertion( "striate nucleus development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021756") -AnnotationAssertion(rdfs:label "striatum development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (caudate nucleus development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0878937420") "The progression of the caudate nucleus over time from its initial formation until its mature state. The caudate nucleus is the C-shaped structures of the striatum containing input neurons involved with control of voluntary movement in the brain.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021757") -AnnotationAssertion(rdfs:label "caudate nucleus development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (putamen development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0878937420") "The progression of the putamen over time from its initial formation until its mature state. The putamen is the lens-shaped basal ganglion involved with control of voluntary movement in the brain.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021758") -AnnotationAssertion(rdfs:label "putamen development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (globus pallidus development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0878937420") "The progression of the globus pallidus over time from its initial formation until its mature state. The globus pallidus is one of the basal ganglia involved with control of voluntary movement in the brain.") -AnnotationAssertion(Annotation( "PMID:16271465") "pallidum development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021759") -AnnotationAssertion(rdfs:label "globus pallidus development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (limbic system development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0878937420") "The progression of the limbic system over time from its initial formation until its mature state. The limbic system is a collection of structures in the brain involved in emotion, motivation and emotional aspects of memory.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021761") -AnnotationAssertion(rdfs:label "limbic system development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (substantia nigra development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") Annotation( "ISBN:0878937420") "The progression of the substantia nigra over time from its initial formation until its mature state. The substantia nigra is the layer of gray substance that separates the posterior parts of the cerebral peduncles (tegmentum mesencephali) from the anterior parts; it normally includes a posterior compact part with many pigmented cells (pars compacta) and an anterior reticular part whose cells contain little pigment (pars reticularis).") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021762") -AnnotationAssertion(rdfs:label "substantia nigra development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (subthalamic nucleus development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0878937420") "The progression of the subthalamic nucleus over time from its initial formation until its mature state. The subthalamic nucleus is the lens-shaped nucleus located in the ventral part of the subthalamus on the inner aspect of the internal capsule that is concerned with the integration of somatic motor function.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "corpus luysi development") -AnnotationAssertion( "GO:0021763") -AnnotationAssertion(rdfs:label "subthalamic nucleus development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (amygdala development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0878937420") "The progression of the amygdala over time from its initial formation until its mature state. The amygdala is an almond-shaped set of neurons in the medial temporal lobe of the brain that play a key role in processing emotions such as fear and pleasure.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021764") -AnnotationAssertion(rdfs:label "amygdala development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cingulate gyrus development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0878937420") "The progression of the cingulate gyrus over time from its initial formation until its mature state. The cingulate gyrus is a ridge in the cerebral cortex located dorsal to the corpus callosum.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021765") -AnnotationAssertion(rdfs:label "cingulate gyrus development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (hippocampus development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0878937420") Annotation( "UBERON:0002421") "The progression of the hippocampus over time from its initial formation until its mature state.") -AnnotationAssertion(Annotation( "ABA:HPF") "hippocampal formation development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021766") -AnnotationAssertion(rdfs:label "hippocampus development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (mammillary body development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0878937420") "The progression of the mammillary body over time from its initial formation until its mature state. The mammillary body is a protrusion at the posterior end of the hypothalamus that contains hypothalamic nuclei.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021767") -AnnotationAssertion(rdfs:label "mammillary body development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (nucleus accumbens development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0878937420") "The progression of the nucleus accumbens over time from its initial formation until its mature state. The nucleus accumbens is a collection of pleomorphic cells in the caudal part of the anterior horn of the lateral ventricle, in the region of the olfactory tubercle, lying between the head of the caudate nucleus and the anterior perforated substance. It is part of the ventral striatum, a composite structure considered part of the basal ganglia.") -AnnotationAssertion( "ventral striatum development") -AnnotationAssertion(Annotation( "GOC:dgh") "accumbens nucleus development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021768") -AnnotationAssertion(rdfs:label "nucleus accumbens development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (orbitofrontal cortex development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0878937420") "The progression of the orbitofrontal cortex over time from its initial formation until its mature state. The orbitofrontal cortex is a cerebral cortex region located in the frontal lobe.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021769") -AnnotationAssertion(rdfs:label "orbitofrontal cortex development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (parahippocampal gyrus development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0878937420") "The progression of the parahippocampal gyrus over time from its initial formation until its mature state. The parahippocampal gyrus is a ridge in the cerebral cortex.") -AnnotationAssertion( "Wikipedia:parahippocampal_gyrus") -AnnotationAssertion(Annotation( "GOC:dgh") "hippocampal gyrus development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021770") -AnnotationAssertion(rdfs:label "parahippocampal gyrus development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (lateral geniculate nucleus development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0878937420") "The progression of the lateral geniculate nucleus over time from its initial formation until its mature state. The lateral geniculate nucleus is the primary processor of visual information received from the retina.") -AnnotationAssertion(Annotation( "GOC:dgh") "LGN development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021771") -AnnotationAssertion(rdfs:label "lateral geniculate nucleus development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (olfactory bulb development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0878937420") "The progression of the olfactory bulb over time from its initial formation until its mature state. The olfactory bulb coordinates neuronal signaling involved in the perception of smell. It receives input from the sensory neurons and outputs to the olfactory cortex.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021772") -AnnotationAssertion(rdfs:label "olfactory bulb development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (glial cell development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process aimed at the progression of a glial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021782") -AnnotationAssertion(rdfs:label "glial cell development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (preganglionic parasympathetic fiber development) - -AnnotationAssertion(Annotation( "GOC:cjm") Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process whose specific outcome is the progression of a preganglionic parasympathetic fiber over time, from its formation to the mature structure. A preganglionic parasympathetic fiber is a cholinergic axonal fiber projecting from the CNS to a parasympathetic ganglion.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021783") -AnnotationAssertion(rdfs:label "preganglionic parasympathetic fiber development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (postganglionic parasympathetic fiber development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process whose specific outcome is the progression of the postganglionic portion of the parasympathetic fiber over time, from its formation to the mature structure. The parasympathetic fiber is one of the two divisions of the vertebrate autonomic nervous system. Parasympathetic nerves emerge cranially as pre ganglionic fibers from oculomotor, facial, glossopharyngeal and vagus and from the sacral region of the spinal cord. Most neurons are cholinergic and responses are mediated by muscarinic receptors. The parasympathetic system innervates, for example: salivary glands, thoracic and abdominal viscera, bladder and genitalia.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021784") -AnnotationAssertion(rdfs:label "postganglionic parasympathetic fiber development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (thalamus development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process in which the thalamus changes over time, from its initial formation to its mature state.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021794") -AnnotationAssertion(rdfs:label "thalamus development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cerebral cortex cell migration) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The orderly movement of cells from one site to another in the cerebral cortex.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021795") -AnnotationAssertion(rdfs:label "cerebral cortex cell migration") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cerebral cortex radially oriented cell migration) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:12626695") "The migration of cells in the developing cerebral cortex in which cells move from the ventricular and/or subventricular zone toward the surface of the brain.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021799") -AnnotationAssertion(rdfs:label "cerebral cortex radially oriented cell migration") -SubClassOf( ) - -# Class: (cerebral cortex radial glia-guided migration) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:12626695") "The radial migration of neuronal or glial precursor cells along radial glial cells during the development of the cerebral cortex.") -AnnotationAssertion( "cerebral cortex radial glia guided migration") -AnnotationAssertion( "cerebral cortex radial glia-dependent cell migration") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "PMID:12626695") "glial-guided locomotion") -AnnotationAssertion( "GO:0021801") -AnnotationAssertion(rdfs:label "cerebral cortex radial glia-guided migration") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cell motility involved in cerebral cortex radial glia guided migration) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:12626695") "The movement of a cell along the process of a radial glial cell involved in cerebral cortex glial-mediated radial migration.") -AnnotationAssertion(Annotation( "GOC:dph") "cell locomotion involved in cerebral cortex glial-mediated radial migration") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") "cell locomotion involved in cerebral cortex radial glia guided migration") -AnnotationAssertion( "GO:0021814") -AnnotationAssertion(rdfs:label "cell motility involved in cerebral cortex radial glia guided migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:12626695") "Rearrangements of the microtubule cytoskeleton that contribute to the movement of cells along radial glial cells as a component of the process of cerebral cortex glial-mediated radial migration.") -AnnotationAssertion(Annotation( "GOC:dph") "modulation of microtubule cytoskeleton involved in cerebral cortex glial-mediated radial migration") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021815") -AnnotationAssertion(rdfs:label "modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (layer formation in cerebral cortex) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:12626695") "The detachment of cells from radial glial fibers at the appropriate time when they cease to migrate and form distinct layer in the cerebral cortex.") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "PMID:12626695") "cerebral cortex lamination") -AnnotationAssertion( "GO:0021819") -AnnotationAssertion(rdfs:label "layer formation in cerebral cortex") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (negative regulation of cell motility involved in cerebral cortex radial glia guided migration) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GOC:tb") Annotation( "GO_REF:0000021") Annotation( "PMID:12626695") "The intracellular signaling pathway that results in the cessation of cell movement involved in lamination of the cerebral cortex.") -AnnotationAssertion( "down regulation of cell locomotion involved in cerebral cortex glial-mediated radial cell migration") -AnnotationAssertion( "down-regulation of cell locomotion involved in cerebral cortex glial-mediated radial cell migration") -AnnotationAssertion( "downregulation of cell locomotion involved in cerebral cortex glial-mediated radial cell migration") -AnnotationAssertion(Annotation( "GOC:dph") "negative regulation of cell locomotion involved in cerebral cortex glial-mediated radial migration") -AnnotationAssertion( "inhibition of cell locomotion involved in cerebral cortex glial-mediated radial cell migration") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "negative regulation of cell locomotion involved in cerebral cortex radial glia guided migration") -AnnotationAssertion( "GO:0021822") -AnnotationAssertion(rdfs:label "negative regulation of cell motility involved in cerebral cortex radial glia guided migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (substrate-independent telencephalic tangential migration) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:12626695") "The process where neuronal precursors migrate tangentially in the telencephalon, primarily guided by interactions that do not require cell-cell contact.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021826") -AnnotationAssertion(rdfs:label "substrate-independent telencephalic tangential migration") -SubClassOf( ) - -# Class: (interneuron migration from the subpallium to the cortex) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:12626695") "The directed movement of interneurons from the subpallium to the cortex during forebrain development.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021830") -AnnotationAssertion(rdfs:label "interneuron migration from the subpallium to the cortex") -SubClassOf( ) - -# Class: (substrate-independent telencephalic tangential interneuron migration) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:12626695") "The directional movement of tangentially migrating interneurons that are not guided by attaching to extracellular substrates.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021843") -AnnotationAssertion(rdfs:label "substrate-independent telencephalic tangential interneuron migration") -SubClassOf( ) - -# Class: (cell proliferation in forebrain) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The creation of greater cell numbers in the forebrain due to cell division of progenitor cells.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021846") -AnnotationAssertion(rdfs:label "cell proliferation in forebrain") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (neuroblast division in subpallium) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:12626695") "The division of neuroblasts in the subpallium area of the forebrain. The interneuron precursors that these cells give rise to include GABAergic interneurons and will migrate tangentially.") -AnnotationAssertion(Annotation( "PMID:16226447") "neuroblast division in the ventral telencephalon") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021848") -AnnotationAssertion(rdfs:label "neuroblast division in subpallium") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (neuroblast division in subventricular zone) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:12626695") "The division of neuroblasts in the subventricular zone of the forebrain. The interneuron precursors that these cells give rise to include adult olfactory bulb interneurons and migrate tangentially.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021849") -AnnotationAssertion(rdfs:label "neuroblast division in subventricular zone") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (pyramidal neuron migration to cerebral cortex) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:12626695") Annotation( "PMID:22192824") "The migration of a pyramidal neuron precursor from the ventricular zone to the correct layer of the cerebral cortex.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/21476"^^xsd:anyURI) -AnnotationAssertion( "pyramidal neuron migration") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "PMID:12626695") "projection neuron migration") -AnnotationAssertion( "GO:0021852") -AnnotationAssertion(rdfs:label "pyramidal neuron migration to cerebral cortex") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cerebral cortex GABAergic interneuron migration) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:12626695") "The migration of GABAergic interneuron precursors from the subpallium to the cerebral cortex.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021853") -AnnotationAssertion(rdfs:label "cerebral cortex GABAergic interneuron migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (hypothalamus development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The progression of the hypothalamus region of the forebrain, from its initial formation to its mature state.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021854") -AnnotationAssertion(rdfs:label "hypothalamus development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (pyramidal neuron differentiation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process in which a neuroblast or one of its progeny commits to a pyramidal neuron fate, migrates from the ventricular zone to the appropriate layer in the cortex and develops into a mature neuron.") -AnnotationAssertion(Annotation( "PMID:16226447") "projection neuron differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021859") -AnnotationAssertion(rdfs:label "pyramidal neuron differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (pyramidal neuron development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The progression of a pyramidal neuron from its initial formation to its mature state.") -AnnotationAssertion(Annotation( "PMID:16226447") "projection neuron development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021860") -AnnotationAssertion(rdfs:label "pyramidal neuron development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (forebrain radial glial cell differentiation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:16226447") "The process in which neuroepithelial cells of the neural tube give rise to radial glial cells, specialized bipotential progenitors cells of the forebrain. Differentiation includes the processes involved in commitment of a cell to a specific fate.") -AnnotationAssertion( "radial glial cell differentiation in forebrain") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021861") -AnnotationAssertion(rdfs:label "forebrain radial glial cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (forebrain neuroblast differentiation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:16226447") "The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of basal progenitor cells, neuroblasts that lose their contacts with the ventricular surface. Differentiation includes the processes involved in commitment of a cell to a specific fate.") -AnnotationAssertion(Annotation( "PMID:16226447") "abventricular progenitor cell differentiation") -AnnotationAssertion(Annotation( "PMID:16226447") "intermediate progenitor cell differentiation") -AnnotationAssertion(Annotation( "PMID:16226447") "non-surface dividing progenitor cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021863") -AnnotationAssertion(rdfs:label "forebrain neuroblast differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (forebrain generation of neurons) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process in which nerve cells are generated in the forebrain. This includes the production of neuroblasts from and their differentiation into neurons.") -AnnotationAssertion( "generation of neurons in forebrain") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021872") -AnnotationAssertion(rdfs:label "forebrain generation of neurons") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (forebrain neuron differentiation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:16226447") "The process in which a relatively unspecialized cell acquires specialized features of a neuron that will reside in the forebrain.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021879") -AnnotationAssertion(rdfs:label "forebrain neuron differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (forebrain neuron development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process whose specific outcome is the progression of a neuron that resides in the forebrain, from its initial commitment to its fate, to the fully functional differentiated cell.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021884") -AnnotationAssertion(rdfs:label "forebrain neuron development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (forebrain cell migration) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The orderly movement of a cell from one site to another at least one of which is located in the forebrain.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021885") -AnnotationAssertion(rdfs:label "forebrain cell migration") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (olfactory bulb interneuron differentiation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:12626695") "The process in which a neuroblast acquires specialized features of an interneuron residing in the olfactory bulb.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021889") -AnnotationAssertion(rdfs:label "olfactory bulb interneuron differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (olfactory bulb interneuron development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:12626695") "The process whose specific outcome is the progression of an interneuron residing in the olfactory bulb, from its initial commitment, to the fully functional differentiated cell.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021891") -AnnotationAssertion(rdfs:label "olfactory bulb interneuron development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cerebral cortex GABAergic interneuron differentiation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:12626695") "The process in which a relatively unspecialized cell acquires specialized features of a GABAergic interneuron residing in the cerebral cortex.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021892") -AnnotationAssertion(rdfs:label "cerebral cortex GABAergic interneuron differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (cerebral cortex GABAergic interneuron development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:12626695") "The process whose specific outcome is the progression of a cerebral cortex GABAergic interneuron over time, from initial commitment to its fate, to the fully functional differentiated cell.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021894") -AnnotationAssertion(rdfs:label "cerebral cortex GABAergic interneuron development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cerebral cortex neuron differentiation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process in which a relatively unspecialized cell acquires specialized features of a neuron residing in the cerebral cortex.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021895") -AnnotationAssertion(rdfs:label "cerebral cortex neuron differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (forebrain astrocyte differentiation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:16226447") "The process in which a relatively unspecialized cell acquires the specialized features of an astrocyte residing in the forebrain. An astrocyte is the most abundant type of glial cell. Astrocytes provide support for neurons and regulate the environment in which they function.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021896") -AnnotationAssertion(rdfs:label "forebrain astrocyte differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (forebrain astrocyte development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process aimed at the progression of an astrocyte that resides in the forebrain, from initial commitment of the cell to its fate, to the fully functional differentiated cell. An astrocyte is the most abundant type of glial cell. Astrocytes provide support for neurons and regulate the environment in which they function.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021897") -AnnotationAssertion(rdfs:label "forebrain astrocyte development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (rostrocaudal neural tube patterning) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:11262869") "The process in which the neural tube is divided into specific regions along the rostrocaudal axis.") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") "anterior-posterior neural tube patterning") -AnnotationAssertion( "GO:0021903") -AnnotationAssertion(rdfs:label "rostrocaudal neural tube patterning") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (forebrain-midbrain boundary formation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:11262869") "The process whose specific outcome is the creation of the forebrain-midbrain boundary.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021905") -AnnotationAssertion(rdfs:label "forebrain-midbrain boundary formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (hindbrain-spinal cord boundary formation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:11262869") "The process whose specific outcome is the formation of the hindbrain-spinal cord boundary.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021906") -AnnotationAssertion(rdfs:label "hindbrain-spinal cord boundary formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (neural tube development) AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process whose specific outcome is the progression of the neural tube over time, from its formation to the mature structure. The mature structure of the neural tube exists when the tube has been segmented into the forebrain, midbrain, hindbrain and spinal cord regions. In addition neural crest has budded away from the epithelium.") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0021915") AnnotationAssertion(rdfs:label "neural tube development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ) @@ -69292,287 +23533,6 @@ SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (regulation of cell proliferation in dorsal spinal cord) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process that modulates the frequency, rate or extent of cell proliferation in the dorsal spinal cord.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021921") -AnnotationAssertion(rdfs:label "regulation of cell proliferation in dorsal spinal cord") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (central nervous system projection neuron axonogenesis) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body towards target cells in a different central nervous system region.") -AnnotationAssertion(Annotation( "GOC:dph") "central nervous system axon tract development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021952") -AnnotationAssertion(rdfs:label "central nervous system projection neuron axonogenesis") -SubClassOf( ) - -# Class: (central nervous system neuron differentiation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process in which a relatively unspecialized cell acquires specialized features of a neuron whose cell body resides in the central nervous system.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021953") -AnnotationAssertion(rdfs:label "central nervous system neuron differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (central nervous system neuron development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process whose specific outcome is the progression of a neuron whose cell body is located in the central nervous system, from initial commitment of the cell to a neuronal fate, to the fully functional differentiated neuron.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021954") -AnnotationAssertion(rdfs:label "central nervous system neuron development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (central nervous system neuron axonogenesis) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "Generation of a long process from a neuron whose cell body resides in the central nervous system. The process carries efferent (outgoing) action potentials from the cell body towards target cells.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021955") -AnnotationAssertion(rdfs:label "central nervous system neuron axonogenesis") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (corticospinal tract morphogenesis) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:9878731") "Generation of a long process of a pyramidal cell, that carries efferent (outgoing) action potentials from the cell body in cerebral cortex layer V towards target cells in the gray matter of the spinal cord. This axonal process is a member of those that make up the corticospinal tract.") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:9878731") "CST axonogenesis") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:9878731") "corticospinal tract axonogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021957") -AnnotationAssertion(rdfs:label "corticospinal tract morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (gracilis tract morphogenesis) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:12867698") "Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the dorsal root ganglion towards target cells in the medulla. This axonal process is a member of those that make up the gracilis tract, a group of axons that are from neurons involved in proprioception from the lower trunk and lower limb.") -AnnotationAssertion(Annotation( "PMID:12867698") "tract of Goll morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021958") -AnnotationAssertion(rdfs:label "gracilis tract morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (cuneatus tract morphogenesis) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:12867698") "Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the dorsal root ganglion towards target cells in the medulla. This axonal process is a member of those that make up the cuneatus tract, a group of axons that are from neurons involved in proprioception from the upper trunk and upper limb.") -AnnotationAssertion(Annotation( "PMID:12867698") "tract of Burdach morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021959") -AnnotationAssertion(rdfs:label "cuneatus tract morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (anterior commissure morphogenesis) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0878937420") "Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in one half of the cerebral cortex towards target cells in the contralateral half. This axonal process is a member of those that make up the anterior commissure, a small midline fiber tract that lies at the anterior end of the corpus callosum.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021960") -AnnotationAssertion(rdfs:label "anterior commissure morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (posterior commissure morphogenesis) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the midbrain towards target cells in the diencephalon.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021961") -AnnotationAssertion(rdfs:label "posterior commissure morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (vestibulospinal tract morphogenesis) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the vestibular nucleus of the pons towards target cells in the spinal cord.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021962") -AnnotationAssertion(rdfs:label "vestibulospinal tract morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (spinothalamic tract morphogenesis) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the spinal cord towards target cells in the thalamus. This axonal process is a member of those that make up the spinothalamic tract, one of the major routes of nociceptive signaling.") -AnnotationAssertion( "dorsolateral tract of Lissauer morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021963") -AnnotationAssertion(rdfs:label "spinothalamic tract morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (rubrospinal tract morphogenesis) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the red nucleus of the midbrain towards target cells in the spinal cord.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021964") -AnnotationAssertion(rdfs:label "rubrospinal tract morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (spinal cord ventral commissure morphogenesis) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process in which the anatomical structures of the spinal cord ventral commissure are generated and organized.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021965") -AnnotationAssertion(rdfs:label "spinal cord ventral commissure morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (trigeminothalamic tract morphogenesis) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0878937420") "Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in spinal cord towards target cells in the thalamus. This axonal process is a member of those that make up the trigeminothalamic tract, one of the major routes of nociceptive and temperature signaling from the face.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021974") -AnnotationAssertion(rdfs:label "trigeminothalamic tract morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (pons reticulospinal tract morphogenesis) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the pons towards target cells in the spinal cord.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021975") -AnnotationAssertion(rdfs:label "pons reticulospinal tract morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (medulla reticulospinal tract morphogenesis) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the medulla towards target cells in the spinal cord.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021976") -AnnotationAssertion(rdfs:label "medulla reticulospinal tract morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (tectospinal tract morphogenesis) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the superior colliculus of the midbrain towards target cells in the ventral spinal cord.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021977") -AnnotationAssertion(rdfs:label "tectospinal tract morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (pineal gland development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The progression of the pineal gland over time from its initial formation until its mature state. The pineal gland is an endocrine gland that secretes melatonin and is involved in circadian rhythms.") -AnnotationAssertion(Annotation( "GOC:dph") "epiphysis development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021982") -AnnotationAssertion(rdfs:label "pineal gland development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (pituitary gland development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The progression of the pituitary gland over time from its initial formation until its mature state. The pituitary gland is an endocrine gland that secretes hormones that regulate many other glands.") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") "hypophysis development") -AnnotationAssertion( "GO:0021983") -AnnotationAssertion(rdfs:label "pituitary gland development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (adenohypophysis development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The progression of the adenohypophysis over time from its initial formation until its mature state. The adenohypophysis is the anterior part of the pituitary. It secretes a variety of hormones and its function is regulated by the hypothalamus.") -AnnotationAssertion( "adenophysis development") -AnnotationAssertion( "anterior pituitary development") -AnnotationAssertion( "anterior pituitary gland development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021984") -AnnotationAssertion(rdfs:label "adenohypophysis development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (neurohypophysis development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The progression of the neurohypophysis over time from its initial formation until its mature state. The neurohypophysis is the part of the pituitary gland that secretes hormones involved in blood pressure regulation.") -AnnotationAssertion( "neurophysis development") -AnnotationAssertion( "posterior pituitary development") -AnnotationAssertion( "posterior pituitary gland development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021985") -AnnotationAssertion(rdfs:label "neurohypophysis development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (habenula development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:9780721601465") "The progression of the habenula over time from its initial formation until its mature state. The habenula is the group of nuclei that makes up the stalk of the pineal gland.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021986") -AnnotationAssertion(rdfs:label "habenula development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cerebral cortex development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The progression of the cerebral cortex over time from its initial formation until its mature state. The cerebral cortex is the outer layered region of the telencephalon.") -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "PMID:25904839") "corticogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") "neocortex development") -AnnotationAssertion( "GO:0021987") -AnnotationAssertion(rdfs:label "cerebral cortex development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (olfactory lobe development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The progression of the olfactory lobe over time from its initial formation until its mature state. The olfactory lobe is the area of the brain that process the neural inputs for the sense of smell.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021988") -AnnotationAssertion(rdfs:label "olfactory lobe development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (olfactory cortex development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The progression of the olfactory cortex over time from its initial formation until its mature state. The olfactory cortex is involved in the perception of smell. It receives input from the olfactory bulb and is responsible for the identification of odors.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021989") -AnnotationAssertion(rdfs:label "olfactory cortex development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (neural plate formation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0878932437") Annotation( "ISBN:0878932585") Annotation( "PMID:15806586") "The formation of the flat, thickened layer of ectodermal cells known as the neural plate. The underlying dorsal mesoderm signals the ectodermal cells above it to elongate into columnar neural plate cells. The neural plate subsequently develops into the neural tube, which gives rise to the central nervous system.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021990") -AnnotationAssertion(rdfs:label "neural plate formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (neuropore closure) AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process of joining together the neural folds at either end of the neural tube.") @@ -69582,38 +23542,6 @@ AnnotationAssertion(rdfs:label "neur SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (lamina terminalis formation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process in which the anterior-most portion of the neural axis is formed by closure of the anterior neuropore.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0021996") -AnnotationAssertion(rdfs:label "lamina terminalis formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (neural plate anterior/posterior regionalization) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process that regulates the coordinated growth and differentiation that establishes the non-random anterior-posterior spatial arrangement of the neural plate.") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") "neural plate anterior/posterior pattern formation") -AnnotationAssertion( "GO:0021999") -AnnotationAssertion(rdfs:label "neural plate anterior/posterior regionalization") -SubClassOf( ) -SubClassOf( ) - -# Class: (zona limitans intrathalamica formation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:11425897") Annotation( "PMID:16452095") "The formation of the narrow stripe of cells that lies between the prospective dorsal and ventral thalami. This boundary contains signals that pattern the prethalamic and thalamic territories of the future mid-diencephalon.") -AnnotationAssertion( "zli biosynthesis") -AnnotationAssertion( "zli formation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0022006") -AnnotationAssertion(rdfs:label "zona limitans intrathalamica formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (neurogenesis) AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "Generation of cells within the nervous system.") @@ -69626,142 +23554,6 @@ AnnotationAssertion(rdfs:label "neur SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (central nervous system vasculogenesis) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The differentiation of endothelial cells from progenitor cells during blood vessel development, and the de novo formation of blood vessels and tubes in the central nervous system. The capillary endothelial cells in the brain are specialized to form the blood-brain barrier.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/21480"^^xsd:anyURI) -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0022009") -AnnotationAssertion(rdfs:label "central nervous system vasculogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (central nervous system myelination) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process in which neuronal axons and dendrites become coated with a segmented lipid-rich sheath (myelin) to enable faster and more energetically efficient conduction of electrical impulses. The sheath is formed by the cell membranes of oligodendrocytes in the central nervous system. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier.") -AnnotationAssertion( "myelination in central nervous system") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0022010") -AnnotationAssertion(rdfs:label "central nervous system myelination") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - -# Class: (myelination in peripheral nervous system) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process in which neuronal axons and dendrites become coated with a segmented lipid-rich sheath (myelin) to enable faster and more energetically efficient conduction of electrical impulses. The sheath is formed by the cell membranes of Schwann cells in the peripheral nervous system. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier.") -AnnotationAssertion( "peripheral nervous system myelination") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0022011") -AnnotationAssertion(rdfs:label "myelination in peripheral nervous system") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (subpallium cell proliferation in forebrain) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The multiplication or reproduction of subpallium cells in the forebrain, resulting in the expansion of a cell population.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0022012") -AnnotationAssertion(rdfs:label "subpallium cell proliferation in forebrain") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (tangential migration from the subventricular zone to the olfactory bulb) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The migration of cells in the telencephalon from the subventricular zone to the olfactory bulb in which cells move orthogonally to the direction of radial migration and do not use radial glial cell processes as substrates for migration.") -AnnotationAssertion( "rostral migratory stream migration") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0022028") -AnnotationAssertion(rdfs:label "tangential migration from the subventricular zone to the olfactory bulb") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (telencephalon cell migration) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The orderly movement of a cell from one site to another at least one of which is located in the telencephalon.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0022029") -AnnotationAssertion(rdfs:label "telencephalon cell migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (telencephalon glial cell migration) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The orderly movement of glial cells through the telencephalon.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0022030") -AnnotationAssertion(rdfs:label "telencephalon glial cell migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (telencephalon astrocyte cell migration) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The orderly movement of an astrocyte cell through the telencephalon.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0022031") -AnnotationAssertion(rdfs:label "telencephalon astrocyte cell migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (telencephalon oligodendrocyte cell migration) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The multiplication or reproduction of telencephalon oligodendrocyte cells, resulting in the expansion of a cell population.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0022032") -AnnotationAssertion(rdfs:label "telencephalon oligodendrocyte cell migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (rhombomere cell migration) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:15629700") "The movement of a cell within a rhombomere. This process is known to occur as an early step in the generation of anatomical structure from a rhombomere.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0022035") -AnnotationAssertion(rdfs:label "rhombomere cell migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (metencephalon development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process whose specific outcome is the progression of the metencephalon over time, from its formation to the mature structure.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0022037") -AnnotationAssertion(rdfs:label "metencephalon development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (corpus callosum development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process whose specific outcome is the progression of the corpus callosum over time, from its formation to the mature structure. The corpus callosum is a thick bundle of nerve fibers comprising a commissural plate connecting the two cerebral hemispheres. It consists of contralateral axon projections that provide communication between the right and left cerebral hemispheres.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0022038") -AnnotationAssertion(rdfs:label "corpus callosum development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cell cycle process) - -AnnotationAssertion(Annotation( "GOC:isa_complete") Annotation( "GOC:mtg_cell_cycle") "The cellular process that ensures successive accurate and complete genome replication and chromosome segregation.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0022402") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "cell cycle process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (molting cycle process) AnnotationAssertion(Annotation( "GOC:isa_complete") "A multicellular organismal process involved in the periodic casting off and regeneration of an outer covering of cuticle, feathers, hair, horns, skin.") @@ -69771,86 +23563,6 @@ AnnotationAssertion(rdfs:label "molt SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (hair cycle process) - -AnnotationAssertion(Annotation( "GOC:isa_complete") "A multicellular organismal process involved in the cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair; one of the collection or mass of filaments growing from the skin of an animal, and forming a covering for a part of the head or for any part or the whole of the body.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0022405") -AnnotationAssertion(rdfs:label "hair cycle process") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (membrane docking) - -AnnotationAssertion(Annotation( "GOC:isa_complete") Annotation( "PMID:27875684") "The initial attachment of a membrane or protein to a target membrane. Docking requires only that the proteins come close enough to interact and adhere.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0022406") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "membrane docking") -SubClassOf( ) - -# Class: (regulation of cell-cell adhesion) - -AnnotationAssertion(Annotation( "GOC:isa_complete") "Any process that modulates the frequency, rate or extent of attachment of a cell to another cell.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0022407") -AnnotationAssertion(rdfs:label "regulation of cell-cell adhesion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (negative regulation of cell-cell adhesion) - -AnnotationAssertion(Annotation( "GOC:isa_complete") "Any process that stops, prevents or reduces the rate or extent of cell adhesion to another cell.") -AnnotationAssertion( "down regulation of cell-cell adhesion") -AnnotationAssertion( "down-regulation of cell-cell adhesion") -AnnotationAssertion( "downregulation of cell-cell adhesion") -AnnotationAssertion( "inhibition of cell-cell adhesion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0022408") -AnnotationAssertion(rdfs:label "negative regulation of cell-cell adhesion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of cell-cell adhesion) - -AnnotationAssertion(Annotation( "GOC:isa_complete") "Any process that activates or increases the rate or extent of cell adhesion to another cell.") -AnnotationAssertion( "up regulation of cell-cell adhesion") -AnnotationAssertion( "up-regulation of cell-cell adhesion") -AnnotationAssertion( "upregulation of cell-cell adhesion") -AnnotationAssertion( "activation of cell-cell adhesion") -AnnotationAssertion( "stimulation of cell-cell adhesion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0022409") -AnnotationAssertion(rdfs:label "positive regulation of cell-cell adhesion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (circadian sleep/wake cycle process) - -AnnotationAssertion(Annotation( "GOC:isa_complete") "A behavioral process involved in the cycle from wakefulness through an orderly succession of sleep states and stages that occurs on an approximately 24 hour rhythm.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0022410") -AnnotationAssertion(rdfs:label "circadian sleep/wake cycle process") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cellular component disassembly) - -AnnotationAssertion(Annotation( "GOC:isa_complete") "A cellular process that results in the breakdown of a cellular component.") -AnnotationAssertion( "GO:0071845") -AnnotationAssertion( "cell structure disassembly") -AnnotationAssertion( "cellular component disassembly at cellular level") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0022411") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "cellular component disassembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -DisjointClasses( ) - # Class: (cellular process involved in reproduction in multicellular organism) AnnotationAssertion(Annotation( "GOC:isa_complete") "A process, occurring at the cellular level, that is involved in the reproductive function of a multicellular organism.") @@ -69858,7 +23570,6 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0022412") AnnotationAssertion(rdfs:label "cellular process involved in reproduction in multicellular organism") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) @@ -69873,7 +23584,6 @@ AnnotationAssertion( "GO:0022414") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "reproductive process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) DisjointClasses( ) # Class: (digestive system process) @@ -69883,7 +23593,6 @@ AnnotationAssertion( "GO:0022600") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "digestive system process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) # Class: (ovulation cycle process) @@ -69900,64 +23609,6 @@ SubClassOf( ObjectSomeValuesFrom( ObjectSomeValuesFrom( )) SubClassOf( ObjectAllValuesFrom( )) -# Class: (regulation of anatomical structure morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of anatomical structure morphogenesis.") -AnnotationAssertion( "regulation of morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0022603") -AnnotationAssertion(rdfs:label "regulation of anatomical structure morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of cell morphogenesis) - -AnnotationAssertion(Annotation( "GOC:isa_complete") "Any process that modulates the frequency, rate or extent of cell morphogenesis. Cell morphogenesis is the developmental process in which the shape of a cell is generated and organized.") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "negative regulation of cell shape and cell size") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "positive regulation of cell shape and cell size") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "regulation of cell shape and cell size") -AnnotationAssertion( "GO:0022604") -AnnotationAssertion(rdfs:label "regulation of cell morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (mammalian oogenesis stage) - -AnnotationAssertion(Annotation( "GOC:isa_complete") Annotation( "GOC:mtg_sensu") "A reproductive process that is a step in the formation and maturation of an ovum or female gamete from a primordial female germ cell.") -AnnotationAssertion( "mammalian oogenesis process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0022605") -AnnotationAssertion(rdfs:label "mammalian oogenesis stage") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cellular component assembly) - -AnnotationAssertion(Annotation( "GOC:isa_complete") "The aggregation, arrangement and bonding together of a cellular component.") -AnnotationAssertion( "GO:0071844") -AnnotationAssertion( "cell structure assembly") -AnnotationAssertion( "cellular component assembly at cellular level") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0022607") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "cellular component assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (gland morphogenesis) - -AnnotationAssertion(Annotation( "GOC:isa_complete") "The process in which the anatomical structures of a gland are generated and organized.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0022612") -AnnotationAssertion(rdfs:label "gland morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (ribonucleoprotein complex biogenesis) AnnotationAssertion(Annotation( "GOC:isa_complete") Annotation( "GOC:mah") "A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a complex containing RNA and proteins. Includes the biosynthesis of the constituent RNA and protein molecules, and those macromolecular modifications that are involved in synthesis or assembly of the ribonucleoprotein complex.") @@ -69968,15 +23619,6 @@ AnnotationAssertion( "ribonucleoprotein complex biogenesis") SubClassOf( ) -# Class: (extracellular matrix disassembly) - -AnnotationAssertion(Annotation( "GOC:jid") "A process that results in the breakdown of the extracellular matrix.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0022617") -AnnotationAssertion(rdfs:label "extracellular matrix disassembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - # Class: (protein-RNA complex assembly) AnnotationAssertion(Annotation( "GOC:jl") "The aggregation, arrangement and bonding together of proteins and RNA molecules to form a ribonucleoprotein complex.") @@ -69987,138 +23629,10 @@ AnnotationAssertion( "GO:0022618") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "protein-RNA complex assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (cytosolic ribosome) - -AnnotationAssertion(Annotation( "GOC:mtg_sensu") "A ribosome located in the cytosol.") -AnnotationAssertion( "GO:0005830") -AnnotationAssertion( "GO:0009281") -AnnotationAssertion( "GO:0030871") -AnnotationAssertion( "70S ribosome") -AnnotationAssertion( "80S ribosome") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0022626") -AnnotationAssertion(rdfs:label "cytosolic ribosome") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - -# Class: (active transmembrane transporter activity) - -AnnotationAssertion(Annotation( "GOC:mtg_transport") Annotation( "ISBN:0815340729") "Enables the transfer of a specific substance or related group of substances from one side of a membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction.") -AnnotationAssertion( "active carrier activity") -AnnotationAssertion( "carrier activity") -AnnotationAssertion( "permease activity") -AnnotationAssertion( "pump activity") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0022804") -AnnotationAssertion(rdfs:label "active transmembrane transporter activity") -SubClassOf( ) - -# Class: (active monoatomic ion transmembrane transporter activity) - -AnnotationAssertion(Annotation( "GOC:mtg_transport") Annotation( "ISBN:0815340729") "Enables the transfer of an ion from one side of a membrane to the other up the solute's concentration gradient. This is carried out by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/24479"^^xsd:anyURI) -AnnotationAssertion( "active ion transmembrane transporter activity") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0022853") -AnnotationAssertion(rdfs:label "active monoatomic ion transmembrane transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (transmembrane transporter activity) - -AnnotationAssertion(Annotation( "GOC:jid") Annotation( "GOC:mtg_transport") Annotation( "ISBN:0815340729") "Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other.") -AnnotationAssertion( "GO:0005386") -AnnotationAssertion( "GO:0015563") -AnnotationAssertion( "GO:0015646") -AnnotationAssertion( "GO:0022891") -AnnotationAssertion( "GO:0022892") -AnnotationAssertion(Annotation(rdfs:label "Egress of internalized antigen to the cytosol via sec61") "Reactome:R-HSA-1236947") -AnnotationAssertion(Annotation(rdfs:label "SLC2A9 transports Fru, Glc, urate") "Reactome:R-HSA-429036") -AnnotationAssertion(Annotation(rdfs:label "Defective SLC2A9 does not transport Fru, Glc, urate") "Reactome:R-HSA-5638209") -AnnotationAssertion(Annotation(rdfs:label "Fe3+ dissociates from SLC22A17:LCN2:2,5DHBA") "Reactome:R-HSA-5671707") -AnnotationAssertion(Annotation(rdfs:label "An unknown carrier transports cytosolic glyoxylate to the peroxisome") "Reactome:R-HSA-6784434") -AnnotationAssertion(Annotation(rdfs:label "An unknown carrier transports mitochondrial glyoxylate to the cytosol") "Reactome:R-HSA-6784436") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "substrate-specific transmembrane transporter activity") -AnnotationAssertion( "substrate-specific transporter activity") -AnnotationAssertion( "uptake permease activity") -AnnotationAssertion( "uptake transmembrane transporter activity") -AnnotationAssertion( "GO:0022857") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "transmembrane transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (macromolecule transmembrane transporter activity) - -AnnotationAssertion(Annotation( "GOC:mtg_transport") Annotation( "ISBN:0815340729") "Enables the transfer of a macromolecule from one side of a membrane to the other.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0022884") -AnnotationAssertion(rdfs:label "macromolecule transmembrane transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (inorganic cation transmembrane transporter activity) - -AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:mtg_transport") Annotation( "ISBN:0815340729") "Enables the transfer of inorganic cations from one side of a membrane to the other. Inorganic cations are atoms or small molecules with a positive charge that do not contain carbon in covalent linkage.") -AnnotationAssertion( "GO:0015077") -AnnotationAssertion( "GO:0015082") -AnnotationAssertion( "GO:0072509") -AnnotationAssertion( "GO:0072510") -AnnotationAssertion(Annotation( "GOC:mah") "di-, tri-valent inorganic cation transmembrane transporter activity") -AnnotationAssertion( "divalent inorganic cation transmembrane transporter activity") -AnnotationAssertion( "monovalent inorganic cation transmembrane transporter activity") -AnnotationAssertion( "trivalent inorganic cation transmembrane transporter activity") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0022890") -AnnotationAssertion(rdfs:label "inorganic cation transmembrane transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of transmembrane transporter activity) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_cardio") Annotation( "GOC:mtg_transport") "Any process that modulates the frequency, rate or extent of transmembrane transporter activity.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0022898") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "regulation of transmembrane transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (signal transduction involved in regulation of gene expression) - -AnnotationAssertion(Annotation( "GOC:mtg_signal") "Any process that modulates the frequency, rate or extent of gene expression as a consequence of a process in which a signal is released and/or conveyed from one location to another.") -AnnotationAssertion( "2010-02-16T09:30:50Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:bf") "regulation of gene expression as a consequence of signal transmission") -AnnotationAssertion( "GO:0023019") -AnnotationAssertion(rdfs:label "signal transduction involved in regulation of gene expression") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (MHC protein complex binding) - -AnnotationAssertion(Annotation( "GOC:mtg_signal") Annotation( "GOC:vw") "Binding to a major histocompatibility complex.") -AnnotationAssertion( "2010-02-16T09:30:50Z") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0023023") -AnnotationAssertion(rdfs:label "MHC protein complex binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (MHC class II protein complex binding) - -AnnotationAssertion(Annotation( "GOC:mtg_signal") Annotation( "GOC:vw") "Binding to a class II major histocompatibility complex.") -AnnotationAssertion( "2010-02-16T09:30:50Z") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0023026") -AnnotationAssertion(rdfs:label "MHC class II protein complex binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - # Class: (regulation of signaling) AnnotationAssertion(Annotation( "GOC:mtg_signal") "Any process that modulates the frequency, rate or extent of a signaling process.") @@ -70128,7 +23642,6 @@ AnnotationAssertion(Annotation( "GOC:mah") "regulation of signalling process") AnnotationAssertion( "GO:0023051") AnnotationAssertion(rdfs:label "regulation of signaling") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (signaling) @@ -70156,34 +23669,6 @@ AnnotationAssertion(rdfs:label "sign SubClassOf( ) DisjointClasses( ) -# Class: (positive regulation of signaling) - -AnnotationAssertion(Annotation( "GOC:mtg_signal") "Any process that activates, maintains or increases the frequency, rate or extent of a signaling process.") -AnnotationAssertion( "2010-02-16T09:30:50Z") -AnnotationAssertion(Annotation( "GOC:mah") "positive regulation of signalling process") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:bf") "positive regulation of signaling process") -AnnotationAssertion( "GO:0023056") -AnnotationAssertion(rdfs:label "positive regulation of signaling") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (negative regulation of signaling) - -AnnotationAssertion(Annotation( "GOC:mtg_signal") "Any process that stops, prevents, or reduces the frequency, rate or extent of a signaling process.") -AnnotationAssertion( "2010-02-16T09:30:50Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:bf") "negative regulation of signaling process") -AnnotationAssertion(Annotation( "GOC:mah") "negative regulation of signalling process") -AnnotationAssertion( "GO:0023057") -AnnotationAssertion(rdfs:label "negative regulation of signaling") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (signal release) AnnotationAssertion(Annotation( "GOC:mtg_signal") "The process in which a signal is secreted or discharged into the extracellular medium from a cellular source.") @@ -70192,49 +23677,8 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:0023061") AnnotationAssertion(rdfs:label "signal release") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (metal ion transport) - -AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of metal ions, any metal ion with an electric charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/23033"^^xsd:anyURI) -AnnotationAssertion( "mah") -AnnotationAssertion( "2009-07-31T01:07:46Z") -AnnotationAssertion( "GO:0070838") -AnnotationAssertion( "GO:0070839") -AnnotationAssertion( "divalent metal ion export") -AnnotationAssertion( "divalent metal ion transport") -AnnotationAssertion( "heavy metal ion transport") -AnnotationAssertion( "metal ion export") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030001") -AnnotationAssertion(rdfs:label "metal ion transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (intracellular monoatomic cation homeostasis) - -AnnotationAssertion(Annotation( "GOC:ceb") Annotation( "GOC:mah") "A homeostatic process involved in the maintenance of a steady state level of monoatomic cations within a cell. Monatomic cations (also called simple cations) are cations consisting of exactly one atom.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/24455"^^xsd:anyURI) -AnnotationAssertion( "cellular cation homeostasis") -AnnotationAssertion( "cellular monoatomic cation homeostasis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030003") -AnnotationAssertion(rdfs:label "intracellular monoatomic cation homeostasis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (establishment of cell polarity) - -AnnotationAssertion(Annotation( "GOC:mah") "The specification and formation of anisotropic intracellular organization or cell growth patterns.") -AnnotationAssertion( "GO:0000283") -AnnotationAssertion( "GO:0030468") -AnnotationAssertion( "cell polarization") -AnnotationAssertion( "bud site selection/establishment of cell polarity") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030010") -AnnotationAssertion(rdfs:label "establishment of cell polarity") -SubClassOf( ) - # Class: (myofibril) AnnotationAssertion(Annotation( "ISBN:0815316194") "The contractile element of skeletal and cardiac muscle; a long, highly organized bundle of actin, myosin, and other proteins that contracts by a sliding filament mechanism.") @@ -70242,98 +23686,8 @@ AnnotationAssertion( "cellular_component") AnnotationAssertion( "GO:0030016") AnnotationAssertion(rdfs:label "myofibril") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (sarcomere) - -AnnotationAssertion(Annotation( "ISBN:0815316194") "The repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs.") -AnnotationAssertion( "Wikipedia:Sarcomere") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0030017") -AnnotationAssertion(rdfs:label "sarcomere") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (actin filament-based process) - -AnnotationAssertion(Annotation( "GOC:mah") "Any cellular process that depends upon or alters the actin cytoskeleton, that part of the cytoskeleton comprising actin filaments and their associated proteins.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "microfilament-based process") -AnnotationAssertion( "GO:0030029") -AnnotationAssertion(rdfs:label "actin filament-based process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (cell projection organization) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "GOC:mah") Annotation( "http://www.cogsci.princeton.edu/~wn/") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon.") -AnnotationAssertion( "cell projection organisation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:mah") "cell projection organization and biogenesis") -AnnotationAssertion(Annotation( "GOC:mah") "cell surface structure organization and biogenesis") -AnnotationAssertion( "GO:0030030") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "cell projection organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (cell projection assembly) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "GOC:mah") Annotation( "http://www.cogsci.princeton.edu/~wn/") "Formation of a prolongation or process extending from a cell, e.g. a flagellum or axon.") -AnnotationAssertion( "formation of a cell surface projection") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:mah") "cell projection biogenesis") -AnnotationAssertion( "GO:0030031") -AnnotationAssertion(rdfs:label "cell projection assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (microvillus assembly) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "ISBN:0815316194") "Formation of a microvillus, a thin cylindrical membrane-covered projection on the surface of a cell.") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:mah") "microvillus biogenesis") -AnnotationAssertion( "GO:0030033") -AnnotationAssertion(rdfs:label "microvillus assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (actin cytoskeleton organization) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:jl") Annotation( "GOC:mah") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/23114"^^xsd:anyURI) -AnnotationAssertion( "actin cytoskeleton organisation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:mah") "actin cytoskeleton organization and biogenesis") -AnnotationAssertion( "actin modulating activity") -AnnotationAssertion( "GO:0030036") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "actin cytoskeleton organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (actin filament-based movement) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mah") "Movement of organelles or other particles along actin filaments, or sliding of actin filaments past each other, mediated by motor proteins.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/19809"^^xsd:anyURI) -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030048") -AnnotationAssertion(rdfs:label "actin filament-based movement") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (vesicle transport along actin filament) - -AnnotationAssertion(Annotation( "GOC:mah") "Movement of a vesicle along an actin filament, mediated by motor proteins.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030050") -AnnotationAssertion(rdfs:label "vesicle transport along actin filament") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - # Class: (cell junction) AnnotationAssertion(Annotation( "GOC:aruk") Annotation( "GOC:bc") Annotation( "GOC:mah") Annotation( "ISBN:0198506732") Annotation( "PMID:26820516") Annotation( "PMID:28096264") Annotation( "http://www.vivo.colostate.edu/hbooks/cmb/cells/pmemb/junctions_a.html") "A cellular component that forms a specialized region of connection between two or more cells, or between a cell and the extracellular matrix, or between two membrane-bound components of a cell, such as flagella.") @@ -70350,23 +23704,12 @@ SubClassOf( ObjectComplementOf(Object SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) DisjointClasses( ObjectSomeValuesFrom( )) -# Class: (insulin processing) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "The formation of mature insulin by proteolysis of the precursor preproinsulin. The signal sequence is first cleaved from preproinsulin to form proinsulin; proinsulin is then cleaved to release the C peptide, leaving the A and B chains of mature insulin linked by disulfide bridges.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030070") -AnnotationAssertion(rdfs:label "insulin processing") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - # Class: (peptide hormone secretion) AnnotationAssertion(Annotation( "GOC:mah") "The regulated release of a peptide hormone from a cell.") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0030072") AnnotationAssertion(rdfs:label "peptide hormone secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) @@ -70377,7 +23720,6 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0030073") AnnotationAssertion(rdfs:label "insulin secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) @@ -70395,7 +23737,6 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0030097") AnnotationAssertion(rdfs:label "hemopoiesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (lymphocyte differentiation) @@ -70408,53 +23749,17 @@ AnnotationAssertion(Annotation( "GO:0030098") AnnotationAssertion(rdfs:comment "Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.") AnnotationAssertion(rdfs:label "lymphocyte differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) -# Class: (myeloid cell differentiation) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") "The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of any cell of the myeloid leukocyte, megakaryocyte, thrombocyte, or erythrocyte lineages.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030099") -AnnotationAssertion(rdfs:label "myeloid cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (regulation of endocytosis) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of endocytosis.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030100") -AnnotationAssertion(rdfs:label "regulation of endocytosis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - # Class: (vasopressin secretion) AnnotationAssertion(Annotation( "GOC:mah") "The regulated release of vasopressin from secretory granules into the blood.") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0030103") AnnotationAssertion(rdfs:label "vasopressin secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (transport vesicle) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "PMID:22160157") "Any of the vesicles of the constitutive secretory pathway, which carry cargo from the endoplasmic reticulum to the Golgi, between Golgi cisternae, from the Golgi to the ER (retrograde transport) or to destinations within or outside the cell.") -AnnotationAssertion( "NIF_Subcellular:sao885490876") -AnnotationAssertion( "constitutive secretory pathway transport vesicle") -AnnotationAssertion( "Golgi to vacuole transport vesicle") -AnnotationAssertion( "Golgi-vacuole transport vesicle") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "secretory vesicle") -AnnotationAssertion( "GO:0030133") -AnnotationAssertion(rdfs:comment "Note that the term 'secretory vesicle' is sometimes used in this sense, but can also mean 'secretory granule ; GO:0030141'.") -AnnotationAssertion(rdfs:label "transport vesicle") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (secretory granule) AnnotationAssertion(Annotation( "GOC:mah") Annotation( "ISBN:0198506732") "A small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion. Secretory granules move towards the periphery of the cell and upon stimulation, their membranes fuse with the cell membrane, and their protein load is exteriorized. Processing of the contained protein may take place in secretory granules.") @@ -70471,32 +23776,6 @@ SubClassOf( ObjectSomeValuesFrom( ObjectSomeValuesFrom( )) DisjointClasses( ObjectSomeValuesFrom( )) -# Class: (sphingolipid biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).") -AnnotationAssertion( "MetaCyc:PWY-5129") -AnnotationAssertion( "sphingolipid anabolism") -AnnotationAssertion( "sphingolipid biosynthesis") -AnnotationAssertion( "sphingolipid formation") -AnnotationAssertion( "sphingolipid synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030148") -AnnotationAssertion(rdfs:label "sphingolipid biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (sphingolipid catabolic process) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).") -AnnotationAssertion( "sphingolipid breakdown") -AnnotationAssertion( "sphingolipid catabolism") -AnnotationAssertion( "sphingolipid degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030149") -AnnotationAssertion(rdfs:label "sphingolipid catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - # Class: (cell differentiation) AnnotationAssertion(Annotation( "ISBN:0198506732") "The cellular developmental process in which a relatively unspecialized cell, e.g. embryonic or regenerative cell, acquires specialized structural and/or functional features that characterize a specific cell. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.") @@ -70511,100 +23790,8 @@ AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (regulation of cell adhesion) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of attachment of a cell to another cell or to the extracellular matrix.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "cell adhesion receptor regulator activity") -AnnotationAssertion( "GO:0030155") -AnnotationAssertion(rdfs:label "regulation of cell adhesion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of proteolysis) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein.") -AnnotationAssertion( "regulation of peptidolysis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030162") -AnnotationAssertion(rdfs:label "regulation of proteolysis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (protein catabolic process) - -AnnotationAssertion(Annotation( "GOC:mah") "The chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/23112"^^xsd:anyURI) -AnnotationAssertion( "GO:0044254") -AnnotationAssertion( "GO:0044257") -AnnotationAssertion( "Wikipedia:Protein_catabolism") -AnnotationAssertion( "cellular protein breakdown") -AnnotationAssertion( "cellular protein catabolic process") -AnnotationAssertion( "cellular protein catabolism") -AnnotationAssertion( "cellular protein degradation") -AnnotationAssertion( "protein breakdown") -AnnotationAssertion( "protein catabolism") -AnnotationAssertion( "protein degradation") -AnnotationAssertion( "multicellular organismal protein catabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "pheromone catabolic process") -AnnotationAssertion( "pheromone catabolism") -AnnotationAssertion( "GO:0030163") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "This term refers to the breakdown of mature proteins. For cleavage events involved in generating a mature protein from a precursor, consider instead the term 'protein maturation ; GO:0051604' and its children.") -AnnotationAssertion(rdfs:label "protein catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (proteoglycan biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans.") -AnnotationAssertion( "proteoglycan anabolism") -AnnotationAssertion( "proteoglycan biosynthesis") -AnnotationAssertion( "proteoglycan formation") -AnnotationAssertion( "proteoglycan synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030166") -AnnotationAssertion(rdfs:label "proteoglycan biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (proteoglycan catabolic process) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans.") -AnnotationAssertion( "proteoglycan breakdown") -AnnotationAssertion( "proteoglycan catabolism") -AnnotationAssertion( "proteoglycan degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030167") -AnnotationAssertion(rdfs:label "proteoglycan catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (platelet activation) - -AnnotationAssertion(Annotation( "http://www.graylab.ac.uk/omd/") "A series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue. These events include shape change, adhesiveness, aggregation, and release reactions. When carried through to completion, these events lead to the formation of a stable hemostatic plug.") -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:pde") "blood coagulation, platelet activation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030168") -AnnotationAssertion(rdfs:label "platelet activation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (neuron differentiation) - -AnnotationAssertion(Annotation( "GOC:mah") "The process in which a relatively unspecialized cell acquires specialized features of a neuron.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030182") -AnnotationAssertion(rdfs:label "neuron differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (B cell differentiation) AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GO_REF:0000022") "The process in which a precursor cell type acquires the specialized features of a B cell. A B cell is a lymphocyte of B lineage with the phenotype CD19-positive and capable of B cell mediated immunity.") @@ -70617,7 +23804,6 @@ AnnotationAssertion(Annotation( "GO:0030183") AnnotationAssertion(rdfs:comment "Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.") AnnotationAssertion(rdfs:label "B cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) @@ -70628,7 +23814,6 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0030186") AnnotationAssertion(rdfs:label "melatonin metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ) @@ -70643,57 +23828,11 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0030187") AnnotationAssertion(rdfs:label "melatonin biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) -# Class: (regulation of blood coagulation) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of blood coagulation.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030193") -AnnotationAssertion(rdfs:label "regulation of blood coagulation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of blood coagulation) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of blood coagulation.") -AnnotationAssertion( "up regulation of blood coagulation") -AnnotationAssertion( "up-regulation of blood coagulation") -AnnotationAssertion( "upregulation of blood coagulation") -AnnotationAssertion( "activation of blood coagulation") -AnnotationAssertion( "stimulation of blood coagulation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030194") -AnnotationAssertion(rdfs:label "positive regulation of blood coagulation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of blood coagulation) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of blood coagulation.") -AnnotationAssertion( "down regulation of blood coagulation") -AnnotationAssertion( "down-regulation of blood coagulation") -AnnotationAssertion( "downregulation of blood coagulation") -AnnotationAssertion( "inhibition of blood coagulation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030195") -AnnotationAssertion(rdfs:label "negative regulation of blood coagulation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - # Class: (extracellular matrix organization) AnnotationAssertion(Annotation( "GOC:mah") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix.") @@ -70705,105 +23844,8 @@ AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "extracellular matrix organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (collagen fibril organization) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "ISBN:0815316194") "Any process that determines the size and arrangement of collagen fibrils within an extracellular matrix.") -AnnotationAssertion( ) -AnnotationAssertion( "collagen fibril organisation") -AnnotationAssertion(Annotation( "GOC:mah") "fibrillar collagen organization") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030199") -AnnotationAssertion(rdfs:label "collagen fibril organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) -DisjointClasses( ObjectSomeValuesFrom( )) - -# Class: (glycosaminoglycan metabolic process) - -AnnotationAssertion(Annotation( "ISBN:0192800981") "The chemical reactions and pathways involving glycosaminoglycans, any of a group of polysaccharides that contain amino sugars.") -AnnotationAssertion( "glycosaminoglycan metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030203") -AnnotationAssertion(rdfs:label "glycosaminoglycan metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (chondroitin sulfate metabolic process) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving chondroitin sulfate, any member of a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues, the repeat units of which consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate. They usually occur linked to a protein to form proteoglycans. Two subgroups exist, one in which the sulfate is on the 4-position (chondroitin sulfate A) and the second in which it is in the 6-position (chondroitin sulfate C). They often are polydisperse and often differ in the degree of sulfation from tissue to tissue. The chains of repeating disaccharide are covalently linked to the side chains of serine residues in the polypeptide backbone of a protein by a glycosidic attachment through the trisaccharide unit galactosyl-galactosyl-xylosyl. Chondroitin sulfate B is more usually known as dermatan sulfate.") -AnnotationAssertion( "chondroitin sulfate metabolism") -AnnotationAssertion( "chondroitin sulphate metabolic process") -AnnotationAssertion( "chondroitin sulphate metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030204") -AnnotationAssertion(rdfs:label "chondroitin sulfate metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (chondroitin sulfate biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of chondroitin sulfate, any member of a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues, the repeat units of which consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate.") -AnnotationAssertion( "chondroitin sulfate anabolism") -AnnotationAssertion( "chondroitin sulfate biosynthesis") -AnnotationAssertion( "chondroitin sulfate formation") -AnnotationAssertion( "chondroitin sulfate synthesis") -AnnotationAssertion( "chondroitin sulphate biosynthesis") -AnnotationAssertion( "chondroitin sulphate biosynthetic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030206") -AnnotationAssertion(rdfs:label "chondroitin sulfate biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (chondroitin sulfate catabolic process) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of chondroitin sulfate, any member of a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues, the repeat units of which consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate.") -AnnotationAssertion( "chondroitin sulfate breakdown") -AnnotationAssertion( "chondroitin sulfate catabolism") -AnnotationAssertion( "chondroitin sulfate degradation") -AnnotationAssertion( "chondroitin sulphate catabolic process") -AnnotationAssertion( "chondroitin sulphate catabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030207") -AnnotationAssertion(rdfs:label "chondroitin sulfate catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (hyaluronan metabolic process) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving hyaluronan, the naturally occurring anionic form of hyaluronic acid, any member of a group of glycosaminoglycans, the repeat units of which consist of beta-1,4 linked D-glucuronyl-beta-(1,3)-N-acetyl-D-glucosamine.") -AnnotationAssertion( "hyaluronan metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030212") -AnnotationAssertion(rdfs:label "hyaluronan metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (hyaluronan biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of hyaluronan, the naturally occurring anionic form of hyaluronic acid, any member of a group of glycosaminoglycans, the repeat units of which consist of beta-1,4 linked D-glucuronyl-beta-(1,3)-N-acetyl-D-glucosamine.") -AnnotationAssertion( "hyaluronan anabolism") -AnnotationAssertion( "hyaluronan biosynthesis") -AnnotationAssertion( "hyaluronan formation") -AnnotationAssertion( "hyaluronan synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030213") -AnnotationAssertion(rdfs:label "hyaluronan biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (hyaluronan catabolic process) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of hyaluronan, the naturally occurring anionic form of hyaluronic acid, any member of a group of glycosaminoglycans, the repeat units of which consist of beta-1,4 linked D-glucuronyl-beta-(1,3)-N-acetyl-D-glucosamine.") -AnnotationAssertion( "hyaluronan breakdown") -AnnotationAssertion( "hyaluronan catabolism") -AnnotationAssertion( "hyaluronan degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030214") -AnnotationAssertion(rdfs:label "hyaluronan catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (keratinocyte differentiation) AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mah") Annotation( "GOC:sdb_2009") Annotation( "GOC:tb") "The process in which a relatively unspecialized cell acquires specialized features of a keratinocyte.") @@ -70811,7 +23853,6 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0030216") AnnotationAssertion(rdfs:label "keratinocyte differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) @@ -70828,239 +23869,9 @@ AnnotationAssertion(Annotation( "GO:0030217") AnnotationAssertion(rdfs:comment "Note that the term 'thymocyte differentiation' was merged into this term because thymocytes are T cells, and thus the term was essentially redundant. Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.") AnnotationAssertion(rdfs:label "T cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) -# Class: (erythrocyte differentiation) - -AnnotationAssertion(Annotation( "GOC:mah") "The process in which a myeloid precursor cell acquires specializes features of an erythrocyte.") -AnnotationAssertion( "Wikipedia:Erythropoiesis") -AnnotationAssertion(Annotation( "CL:0000232") "RBC differentiation") -AnnotationAssertion( "erythrocyte cell differentiation") -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:dph") "erythropoiesis") -AnnotationAssertion(Annotation( "CL:0000232") "red blood cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030218") -AnnotationAssertion(rdfs:label "erythrocyte differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (megakaryocyte differentiation) - -AnnotationAssertion(Annotation( "GOC:mah") "The process in which a myeloid precursor cell acquires specializes features of a megakaryocyte.") -AnnotationAssertion( "megakaryocyte cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030219") -AnnotationAssertion(rdfs:label "megakaryocyte differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (platelet formation) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "ISBN:0815316194") "The process in which platelets bud from long processes extended by megakaryocytes.") -AnnotationAssertion(Annotation( "GOC:curators") Annotation( ) "platelet extrusion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030220") -AnnotationAssertion(rdfs:label "platelet formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (neutrophil differentiation) - -AnnotationAssertion(Annotation( "GOC:mah") "The process in which a myeloid precursor cell acquires the specialized features of a neutrophil.") -AnnotationAssertion( "neutrophil cell differentiation") -AnnotationAssertion(Annotation( "GOC:yaf") "neutrophil granulocyte differentiation") -AnnotationAssertion(Annotation( "GOC:yaf") "neutrophil granulocytopoiesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030223") -AnnotationAssertion(rdfs:label "neutrophil differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (monocyte differentiation) - -AnnotationAssertion(Annotation( "GOC:mah") "The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a monocyte.") -AnnotationAssertion( "monocyte cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030224") -AnnotationAssertion(rdfs:label "monocyte differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (macrophage differentiation) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") "The process in which a relatively unspecialized monocyte acquires the specialized features of a macrophage.") -AnnotationAssertion( "macrophage cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030225") -AnnotationAssertion(rdfs:label "macrophage differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (myofibril assembly) - -AnnotationAssertion(Annotation( "GOC:mah") "Formation of myofibrils, the repeating units of striated muscle.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030239") -AnnotationAssertion(rdfs:label "myofibril assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cellulose metabolic process) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation.") -AnnotationAssertion( "GO:0016177") -AnnotationAssertion( "cellulose metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030243") -AnnotationAssertion(rdfs:label "cellulose metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cellulose biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation.") -AnnotationAssertion( "GO:0016178") -AnnotationAssertion( "MetaCyc:PWY-1001") -AnnotationAssertion( "cellulose anabolism") -AnnotationAssertion( "cellulose biosynthesis") -AnnotationAssertion( "cellulose formation") -AnnotationAssertion( "cellulose synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030244") -AnnotationAssertion(rdfs:label "cellulose biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cellulose catabolic process) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation.") -AnnotationAssertion( "GO:0016179") -AnnotationAssertion( "cellulose breakdown") -AnnotationAssertion( "cellulose catabolism") -AnnotationAssertion( "cellulose degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030245") -AnnotationAssertion(rdfs:label "cellulose catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (carbohydrate binding) - -AnnotationAssertion(Annotation( "GOC:mah") "Binding to a carbohydrate, which includes monosaccharides, oligosaccharides and polysaccharides as well as substances derived from monosaccharides by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom. Cyclitols are generally not regarded as carbohydrates.") -AnnotationAssertion( "GO:0005529") -AnnotationAssertion( "sugar binding") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "selectin") -AnnotationAssertion( "GO:0030246") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "carbohydrate binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (polysaccharide binding) - -AnnotationAssertion(Annotation( "GOC:mah") "Binding to a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically.") -AnnotationAssertion( "GO:0002506") -AnnotationAssertion( "polysaccharide assembly with MHC class II protein complex") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0030247") -AnnotationAssertion(rdfs:label "polysaccharide binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cellulose binding) - -AnnotationAssertion(Annotation( "GOC:mah") "Binding to cellulose.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0030248") -AnnotationAssertion(rdfs:label "cellulose binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (growth hormone secretion) - -AnnotationAssertion(Annotation( "GOC:mah") "The regulated release of growth hormone from secretory granules into the blood.") -AnnotationAssertion(Annotation( "GOC:mah") "somatotropin secretion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030252") -AnnotationAssertion(rdfs:label "growth hormone secretion") -SubClassOf( ) - -# Class: (chromosome condensation) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "ISBN:0815316194") "The progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis, in eukaryotic cells.") -AnnotationAssertion( "GO:0000068") -AnnotationAssertion(Annotation( "Wikipedia:DNA_condensation") "DNA condensation") -AnnotationAssertion(Annotation( "GOC:bf") "eukaryotic chromosome condensation") -AnnotationAssertion(Annotation( "GOC:bf") "nuclear chromosome condensation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030261") -AnnotationAssertion(rdfs:label "chromosome condensation") -SubClassOf( ) - -# Class: (apoptotic nuclear changes) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:mtg_apoptosis") "Alterations undergone by nuclei at the molecular and morphological level as part of the execution phase of apoptosis.") -AnnotationAssertion( "apoptotic nuclear change") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030262") -AnnotationAssertion(rdfs:label "apoptotic nuclear changes") -SubClassOf( ) - -# Class: (apoptotic chromosome condensation) - -AnnotationAssertion(Annotation( "GOC:mah") "The compaction of chromatin during apoptosis.") -AnnotationAssertion( "Wikipedia:Pyknosis") -AnnotationAssertion( "pyknosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030263") -AnnotationAssertion(rdfs:label "apoptotic chromosome condensation") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (nuclear fragmentation involved in apoptotic nuclear change) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mah") Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:tb") Annotation( "ISBN:0721639976") "The breakdown of the nucleus into small membrane-bounded compartments, or blebs, each of which contain compacted DNA.") -AnnotationAssertion( "apoptotic nuclear fragmentation") -AnnotationAssertion( "nucleus fragmentation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "nuclear fragmentation during apoptosis") -AnnotationAssertion( "GO:0030264") -AnnotationAssertion(rdfs:label "nuclear fragmentation involved in apoptotic nuclear change") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of ossification) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance.") -AnnotationAssertion( "regulation of bone biosynthesis") -AnnotationAssertion( "regulation of bone formation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030278") -AnnotationAssertion(rdfs:label "regulation of ossification") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of ossification) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance.") -AnnotationAssertion( "down regulation of ossification") -AnnotationAssertion( "down-regulation of ossification") -AnnotationAssertion( "downregulation of ossification") -AnnotationAssertion( "negative regulation of bone biosynthesis") -AnnotationAssertion( "negative regulation of bone formation") -AnnotationAssertion( "inhibition of ossification") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030279") -AnnotationAssertion(rdfs:label "negative regulation of ossification") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - # Class: (bone mineralization) AnnotationAssertion(Annotation( "GOC:mah") Annotation( "PMID:22936354") "The deposition of hydroxyapatite, a form of calcium phosphate with the formula Ca10(PO4)6(OH)2, in bone tissue.") @@ -71068,41 +23879,9 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0030282") AnnotationAssertion(rdfs:label "bone mineralization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (positive regulation of cell growth) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate, extent or direction of cell growth.") -AnnotationAssertion( "up regulation of cell growth") -AnnotationAssertion( "up-regulation of cell growth") -AnnotationAssertion( "upregulation of cell growth") -AnnotationAssertion( "activation of cell growth") -AnnotationAssertion( "stimulation of cell growth") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030307") -AnnotationAssertion(rdfs:label "positive regulation of cell growth") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of cell growth) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate, extent or direction of cell growth.") -AnnotationAssertion( "down regulation of cell growth") -AnnotationAssertion( "down-regulation of cell growth") -AnnotationAssertion( "downregulation of cell growth") -AnnotationAssertion( "inhibition of cell growth") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030308") -AnnotationAssertion(rdfs:label "negative regulation of cell growth") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - # Class: (external encapsulating structure) AnnotationAssertion(Annotation( "GOC:go_curators") "A structure that lies outside the plasma membrane and surrounds the entire cell or cells. This does not include the periplasmic space.") @@ -71119,129 +23898,6 @@ SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (osteoclast differentiation) - -AnnotationAssertion(Annotation( "CL:0000092") Annotation( "GOC:add") Annotation( "ISBN:0781735149") Annotation( "PMID:12161749") "The process in which a relatively unspecialized monocyte acquires the specialized features of an osteoclast. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue.") -AnnotationAssertion( "osteoclast cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030316") -AnnotationAssertion(rdfs:label "osteoclast differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (flagellated sperm motility) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:cilia") Annotation( "GOC:krc") Annotation( "GO_REF:0000060") Annotation( "PMID:26680031") "The directed, self-propelled movement of a cilium (aka flagellum) that contributes to the movement of a flagellated sperm.") -AnnotationAssertion( "GO:0097724") -AnnotationAssertion( "GO:1905419") -AnnotationAssertion( "sperm motility") -AnnotationAssertion( "sperm movement") -AnnotationAssertion( "Wikipedia:Sperm_motility") -AnnotationAssertion( "flagellated sperm movement") -AnnotationAssertion(Annotation( "GOC:cilia") Annotation( "GOC:krc") "sperm flagellum movement") -AnnotationAssertion( "sperm flagellum movement involved in flagellated sperm motility") -AnnotationAssertion(Annotation( "GOC:TermGenie") "sperm flagellum movement involved in flagellated sperm movement") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030317") -AnnotationAssertion(rdfs:label "flagellated sperm motility") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (melanocyte differentiation) - -AnnotationAssertion(Annotation( "GOC:mah") "The process in which a relatively unspecialized cell acquires specialized features of a melanocyte.") -AnnotationAssertion( "melanocyte cell differentiation") -AnnotationAssertion( "melanophore differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030318") -AnnotationAssertion(rdfs:label "melanocyte differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (respiratory tube development) - -AnnotationAssertion(Annotation( "GOC:jid") "The process whose specific outcome is the progression of the respiratory tube over time, from its formation to the mature structure. The respiratory tube is assumed to mean any tube in the respiratory tract.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030323") -AnnotationAssertion(rdfs:label "respiratory tube development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (lung development) - -AnnotationAssertion(Annotation( "GOC:jid") Annotation( "UBERON:0002048") "The process whose specific outcome is the progression of the lung over time, from its formation to the mature structure. In all air-breathing vertebrates the lungs are developed from the ventral wall of the oesophagus as a pouch which divides into two sacs. In amphibians and many reptiles the lungs retain very nearly this primitive sac-like character, but in the higher forms the connection with the esophagus becomes elongated into the windpipe and the inner walls of the sacs become more and more divided, until, in the mammals, the air spaces become minutely divided into tubes ending in small air cells, in the walls of which the blood circulates in a fine network of capillaries. In mammals the lungs are more or less divided into lobes, and each lung occupies a separate cavity in the thorax.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030324") -AnnotationAssertion(rdfs:label "lung development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (adrenal gland development) - -AnnotationAssertion(Annotation( "GOC:dgh") "The process whose specific outcome is the progression of the adrenal gland over time, from its formation to the mature structure. This gland can either be a discrete structure located bilaterally above each kidney, or a cluster of cells in the head kidney that perform the functions of the adrenal gland. In either case, this organ consists of two cells types, aminergic chromaffin cells and steroidogenic cortical cells.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "interrenal gland") -AnnotationAssertion( "GO:0030325") -AnnotationAssertion(rdfs:label "adrenal gland development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (regulation of cell migration) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of cell migration.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030334") -AnnotationAssertion(rdfs:label "regulation of cell migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (positive regulation of cell migration) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of cell migration.") -AnnotationAssertion( "up regulation of cell migration") -AnnotationAssertion( "up-regulation of cell migration") -AnnotationAssertion( "upregulation of cell migration") -AnnotationAssertion( "activation of cell migration") -AnnotationAssertion( "stimulation of cell migration") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030335") -AnnotationAssertion(rdfs:label "positive regulation of cell migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of cell migration) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of cell migration.") -AnnotationAssertion( "down regulation of cell migration") -AnnotationAssertion( "down-regulation of cell migration") -AnnotationAssertion( "downregulation of cell migration") -AnnotationAssertion( "inhibition of cell migration") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030336") -AnnotationAssertion(rdfs:label "negative regulation of cell migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (membrane disassembly) - -AnnotationAssertion(Annotation( "GOC:mah") "The controlled breakdown of any cell membrane in the context of a normal process such as autophagy.") -AnnotationAssertion( "membrane breakdown") -AnnotationAssertion( "membrane catabolism") -AnnotationAssertion( "membrane degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030397") -AnnotationAssertion(rdfs:label "membrane disassembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - # Class: (defecation) AnnotationAssertion(Annotation( "GOC:mah") "The expulsion of feces from the rectum.") @@ -71275,19 +23931,6 @@ SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (sleep) - -AnnotationAssertion(Annotation( "ISBN:0192800981") "Any process in which an organism enters and maintains a periodic, readily reversible state of reduced awareness and metabolic activity. Usually accompanied by physical relaxation, the onset of sleep in humans and other mammals is marked by a change in the electrical activity of the brain.") -AnnotationAssertion( "Wikipedia:Sleep") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "diapause") -AnnotationAssertion( "dormancy") -AnnotationAssertion( "lethargus") -AnnotationAssertion( "GO:0030431") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "sleep") -SubClassOf( ) - # Class: (peristalsis) AnnotationAssertion(Annotation( "ISBN:0198506732") "A wavelike sequence of involuntary muscular contraction and relaxation that passes along a tubelike structure, such as the intestine, impelling the contents onwards.") @@ -71297,258 +23940,14 @@ AnnotationAssertion( "peristalsis") SubClassOf( ) -# Class: (nuclear migration along microtubule) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:sgd_curators") "The directed movement of the nucleus along microtubules within the cell, mediated by motor proteins.") -AnnotationAssertion( "GO:0000065") -AnnotationAssertion( "nuclear movement, microtubule-mediated") -AnnotationAssertion( "nucleus migration") -AnnotationAssertion( "microtubule cytoskeleton-dependent nuclear positioning") -AnnotationAssertion( "microtubule cytoskeleton-dependent nucleus positioning") -AnnotationAssertion( "microtubule-dependent nuclear positioning") -AnnotationAssertion( "microtubule-dependent nucleus positioning") -AnnotationAssertion( "microtubule-mediated nuclear migration") -AnnotationAssertion( "nuclear migration, microtubule-mediated") -AnnotationAssertion( "transport of nucleus by microtubules") -AnnotationAssertion( "transport of nucleus, microtubule-mediated") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030473") -AnnotationAssertion(rdfs:label "nuclear migration along microtubule") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (smooth muscle contractile fiber) - -AnnotationAssertion(Annotation( "GOC:mah") "The contractile fiber of smooth muscle cells.") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0030485") -AnnotationAssertion(rdfs:label "smooth muscle contractile fiber") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of bone mineralization) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of bone mineralization.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030500") -AnnotationAssertion(rdfs:label "regulation of bone mineralization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of bone mineralization) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of bone mineralization.") -AnnotationAssertion( "up regulation of bone mineralization") -AnnotationAssertion( "up-regulation of bone mineralization") -AnnotationAssertion( "upregulation of bone mineralization") -AnnotationAssertion( "activation of bone mineralization") -AnnotationAssertion( "stimulation of bone mineralization") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030501") -AnnotationAssertion(rdfs:label "positive regulation of bone mineralization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of bone mineralization) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of bone mineralization.") -AnnotationAssertion( "down regulation of bone mineralization") -AnnotationAssertion( "down-regulation of bone mineralization") -AnnotationAssertion( "downregulation of bone mineralization") -AnnotationAssertion( "inhibition of bone mineralization") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030502") -AnnotationAssertion(rdfs:label "negative regulation of bone mineralization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (intracellular steroid hormone receptor signaling pathway) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:signaling") "The series of molecular signals initiated by a steroid binding to an intracellular steroid hormone receptor.") -AnnotationAssertion(Annotation( "GOC:bf") "steroid hormone receptor signaling pathway") -AnnotationAssertion(Annotation( "GOC:bf") "steroid hormone receptor signalling pathway") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030518") -AnnotationAssertion(rdfs:label "intracellular steroid hormone receptor signaling pathway") -SubClassOf( ) -SubClassOf( ) - -# Class: (intracellular receptor signaling pathway) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:mah") "The series of molecular signals initiated by a ligand binding to a receptor located within a cell.") -AnnotationAssertion( "intracellular receptor mediated signaling pathway") -AnnotationAssertion( "intracellular receptor-mediated signaling pathway") -AnnotationAssertion( "intracellular receptor-mediated signalling pathway") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030522") -AnnotationAssertion(rdfs:label "intracellular receptor signaling pathway") -SubClassOf( ) - -# Class: (male genitalia development) - -AnnotationAssertion(Annotation( "GOC:ems") Annotation( "ISBN:0140512888") "The process whose specific outcome is the progression of the male genitalia over time, from its formation to the mature structure.") -AnnotationAssertion( "male genital development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030539") -AnnotationAssertion(rdfs:label "male genitalia development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (female genitalia development) - -AnnotationAssertion(Annotation( "GOC:mah") "The process whose specific outcome is the progression of the female genitalia over time, from formation to the mature structure.") -AnnotationAssertion( "female genital development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030540") -AnnotationAssertion(rdfs:label "female genitalia development") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (adenyl nucleotide binding) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "Binding to an adenyl nucleotide, an adenosine esterified with (ortho)phosphate.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0030554") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "adenyl nucleotide binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (bile acid catabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways resulting in the breakdown of bile acids, any of a group of steroid carboxylic acids occurring in bile.") -AnnotationAssertion( "GO:0019613") -AnnotationAssertion( "MetaCyc:7ALPHADEHYDROX-PWY") -AnnotationAssertion( "bile acid breakdown") -AnnotationAssertion( "bile acid catabolism") -AnnotationAssertion( "bile acid degradation") -AnnotationAssertion( "bile acid 7alpha-dehydroxylation pathway") -AnnotationAssertion( "cholate catabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030573") -AnnotationAssertion(rdfs:label "bile acid catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (collagen catabolic process) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "ISBN:0815316194") "The proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix, usually carried out by proteases secreted by nearby cells.") -AnnotationAssertion( "collagen breakdown") -AnnotationAssertion( "collagen catabolism") -AnnotationAssertion( "collagen degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030574") -AnnotationAssertion(rdfs:label "collagen catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (neutrophil chemotaxis) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0198506732") "The directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030593") -AnnotationAssertion(rdfs:label "neutrophil chemotaxis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (neurotransmitter receptor activity) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "GOC:signaling") "Combining with a neurotransmitter and transmitting the signal to initiate a change in cell activity.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0030594") -AnnotationAssertion(rdfs:comment "A strict definition of neurotransmitter receptor activity would limit its use to receptor activity at the postsynaptic membrane as part of synaptic transmission, but we recognize that usage is often much broader than this. For the strict use case, please see 'postsynaptic neurotransmitter receptor activity'") -AnnotationAssertion(rdfs:label "neurotransmitter receptor activity") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - -# Class: (leukocyte chemotaxis) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:jl") "The movement of a leukocyte in response to an external stimulus.") -AnnotationAssertion( "immune cell chemotaxis") -AnnotationAssertion( "leucocyte chemotaxis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030595") -AnnotationAssertion(rdfs:label "leukocyte chemotaxis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (intracellular sulfate ion homeostasis) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "PMID:24193406") "A homeostatic process involved in the maintenance of a steady state level of sulfate ions within a cell.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/24514"^^xsd:anyURI) -AnnotationAssertion( "sulphate ion homeostasis") -AnnotationAssertion( "cellular sulfate ion homeostasis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030642") -AnnotationAssertion(rdfs:label "intracellular sulfate ion homeostasis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (intracellular phosphate ion homeostasis) - -AnnotationAssertion(Annotation( "GOC:mah") "A homeostatic process involved in the maintenance of a steady state level of phosphate ions within a cell.") -AnnotationAssertion( "cellular phosphate ion homeostasis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030643") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "intracellular phosphate ion homeostasis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (glucose catabolic process to butyrate) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "The anaerobic chemical reactions and pathways resulting in the breakdown of glucose, with the production of acetic acid, butyric acid, carbon dioxide (CO2), and dihydrogen; effected by some saccharolytic species of Clostridium, e.g. C. butyricum.") -AnnotationAssertion( "butyrate fermentation") -AnnotationAssertion( "glucose fermentation to butyrate") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030645") -AnnotationAssertion(rdfs:label "glucose catabolic process to butyrate") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (transport vesicle membrane) - -AnnotationAssertion(Annotation( "GOC:mah") "The lipid bilayer surrounding a transport vesicle.") -AnnotationAssertion( "secretory vesicle membrane") -AnnotationAssertion( "constitutive secretory pathway transport vesicle membrane") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0030658") -AnnotationAssertion(rdfs:label "transport vesicle membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (cytoplasmic vesicle membrane) AnnotationAssertion(Annotation( "GOC:mah") "The lipid bilayer surrounding a cytoplasmic vesicle.") AnnotationAssertion( "cellular_component") AnnotationAssertion( "GO:0030659") AnnotationAssertion(rdfs:label "cytoplasmic vesicle membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (Golgi-associated vesicle membrane) - -AnnotationAssertion(Annotation( "GOC:mah") "The lipid bilayer surrounding a vesicle associated with the Golgi apparatus.") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "Golgi vesicle membrane") -AnnotationAssertion( "GO:0030660") -AnnotationAssertion(rdfs:label "Golgi-associated vesicle membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (chitosome membrane) - -AnnotationAssertion(Annotation( "GOC:mah") "The lipid bilayer surrounding a chitosome.") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0030661") -AnnotationAssertion(rdfs:label "chitosome membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (secretory granule membrane) AnnotationAssertion(Annotation( "GOC:mah") "The lipid bilayer surrounding a secretory granule.") @@ -71556,287 +23955,18 @@ AnnotationAssertion( "cellular_component") AnnotationAssertion( "GO:0030667") AnnotationAssertion(rdfs:label "secretory granule membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (eggshell formation) - -AnnotationAssertion(Annotation( "GOC:mtg_sensu") Annotation( "ISBN:0879694238") Annotation( "PMID:10822261") "Construction of the eggshell, a product of the somatic follicle cell epithelium and a structure that supports the egg in a hostile environment, minimizing water loss whilst allowing gas exchanges essential for embryonic respiration.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030703") -AnnotationAssertion(rdfs:label "eggshell formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - -# Class: (vitelline membrane formation) - -AnnotationAssertion(Annotation( "ISBN:0879694238") "Construction of the vitelline membrane portion of the egg shell, a rigid structure required to maintain the shape of the egg.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030704") -AnnotationAssertion(rdfs:label "vitelline membrane formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (cytoskeleton-dependent intracellular transport) - -AnnotationAssertion(Annotation( "GOC:mah") "The directed movement of substances along cytoskeletal fibers such as microfilaments or microtubules within a cell.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030705") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "cytoskeleton-dependent intracellular transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (follicle cell of egg chamber development) - -AnnotationAssertion(Annotation( "GOC:mtg_sensu") Annotation( "PMID:10822261") "The process that occurs during oogenesis involving the ovarian follicle cells, somatic cells which surround the germ cells of an ovary. An example of this is found in Drosophila melanogaster.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030707") -AnnotationAssertion(rdfs:label "follicle cell of egg chamber development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - -# Class: (germ-line stem cell population maintenance) - -AnnotationAssertion(Annotation( "ISBN:0879694238") "Any process by which an organism or tissue maintains a population of germ-line stem cells.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030718") -AnnotationAssertion(rdfs:label "germ-line stem cell population maintenance") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (oocyte localization involved in germarium-derived egg chamber formation) - -AnnotationAssertion(Annotation( "GOC:mtg_sensu") Annotation( "PMID:10449356") "Directed movement of the oocyte, following its specification, from its original central position in the cyst to a posterior position relative to the nurse cells of the egg chamber, and its maintenance in this posterior location. This is the first sign of anterior-posterior asymmetry in the developing egg chamber.") -AnnotationAssertion( "establishment and maintenance of oocyte localization in egg chamber") -AnnotationAssertion( "establishment and maintenance of oocyte position during oogenesis") -AnnotationAssertion(Annotation( "GOC:mah") "oocyte localisation involved in germarium-derived egg chamber formation") -AnnotationAssertion( "oogenesis, establishment and maintenance of oocyte localization") -AnnotationAssertion( "oogenesis, oocyte localization") -AnnotationAssertion( "oocyte positioning during oogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "oocyte localization during germarium-derived egg chamber formation") -AnnotationAssertion( "oocyte localization during oogenesis") -AnnotationAssertion( "GO:0030720") -AnnotationAssertion(rdfs:label "oocyte localization involved in germarium-derived egg chamber formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - -# Class: (regulation of nucleotide biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nucleotides.") -AnnotationAssertion( "regulation of nucleotide anabolism") -AnnotationAssertion( "regulation of nucleotide biosynthesis") -AnnotationAssertion( "regulation of nucleotide formation") -AnnotationAssertion( "regulation of nucleotide synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030808") -AnnotationAssertion(rdfs:label "regulation of nucleotide biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of nucleotide biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nucleotides.") -AnnotationAssertion( "down regulation of nucleotide biosynthetic process") -AnnotationAssertion( "down-regulation of nucleotide biosynthetic process") -AnnotationAssertion( "downregulation of nucleotide biosynthetic process") -AnnotationAssertion( "negative regulation of nucleotide anabolism") -AnnotationAssertion( "negative regulation of nucleotide biosynthesis") -AnnotationAssertion( "negative regulation of nucleotide formation") -AnnotationAssertion( "negative regulation of nucleotide synthesis") -AnnotationAssertion( "inhibition of nucleotide biosynthetic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030809") -AnnotationAssertion(rdfs:label "negative regulation of nucleotide biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of nucleotide biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nucleotides.") -AnnotationAssertion( "positive regulation of nucleotide anabolism") -AnnotationAssertion( "positive regulation of nucleotide biosynthesis") -AnnotationAssertion( "positive regulation of nucleotide formation") -AnnotationAssertion( "positive regulation of nucleotide synthesis") -AnnotationAssertion( "up regulation of nucleotide biosynthetic process") -AnnotationAssertion( "up-regulation of nucleotide biosynthetic process") -AnnotationAssertion( "upregulation of nucleotide biosynthetic process") -AnnotationAssertion( "activation of nucleotide biosynthetic process") -AnnotationAssertion( "stimulation of nucleotide biosynthetic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030810") -AnnotationAssertion(rdfs:label "positive regulation of nucleotide biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of nucleotide catabolic process) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of nucleotides.") -AnnotationAssertion( "regulation of nucleotide breakdown") -AnnotationAssertion( "regulation of nucleotide catabolism") -AnnotationAssertion( "regulation of nucleotide degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030811") -AnnotationAssertion(rdfs:label "regulation of nucleotide catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of nucleotide catabolic process) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of nucleotides.") -AnnotationAssertion( "down regulation of nucleotide catabolic process") -AnnotationAssertion( "down-regulation of nucleotide catabolic process") -AnnotationAssertion( "downregulation of nucleotide catabolic process") -AnnotationAssertion( "negative regulation of nucleotide breakdown") -AnnotationAssertion( "negative regulation of nucleotide catabolism") -AnnotationAssertion( "negative regulation of nucleotide degradation") -AnnotationAssertion( "inhibition of nucleotide catabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030812") -AnnotationAssertion(rdfs:label "negative regulation of nucleotide catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of nucleotide catabolic process) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of nucleotides.") -AnnotationAssertion( "positive regulation of nucleotide breakdown") -AnnotationAssertion( "positive regulation of nucleotide catabolism") -AnnotationAssertion( "positive regulation of nucleotide degradation") -AnnotationAssertion( "up regulation of nucleotide catabolic process") -AnnotationAssertion( "up-regulation of nucleotide catabolic process") -AnnotationAssertion( "upregulation of nucleotide catabolic process") -AnnotationAssertion( "activation of nucleotide catabolic process") -AnnotationAssertion( "stimulation of nucleotide catabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030813") -AnnotationAssertion(rdfs:label "positive regulation of nucleotide catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (prostate gland development) - -AnnotationAssertion(Annotation( "PMID:11839751") "The process whose specific outcome is the progression of the prostate gland over time, from its formation to the mature structure. The prostate gland is a partly muscular, partly glandular body that is situated near the base of the mammalian male urethra and secretes an alkaline viscid fluid which is a major constituent of the ejaculatory fluid.") -AnnotationAssertion( "prostate development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030850") -AnnotationAssertion(rdfs:label "prostate gland development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (granulocyte differentiation) - -AnnotationAssertion(Annotation( "GOC:ecd") Annotation( "http://life.nthu.edu.tw/~g864204/dict-search1.htm") "The process in which a myeloid precursor cell acquires the specialized features of a granulocyte. Granulocytes are a class of leukocytes characterized by the presence of granules in their cytoplasm. These cells are active in allergic immune reactions such as arthritic inflammation and rashes. This class includes basophils, eosinophils and neutrophils.") -AnnotationAssertion( "granulocyte cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030851") -AnnotationAssertion(rdfs:label "granulocyte differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of granulocyte differentiation) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of granulocyte differentiation.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030852") -AnnotationAssertion(rdfs:label "regulation of granulocyte differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of granulocyte differentiation) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of granulocyte differentiation.") -AnnotationAssertion( "down regulation of granulocyte differentiation") -AnnotationAssertion( "down-regulation of granulocyte differentiation") -AnnotationAssertion( "downregulation of granulocyte differentiation") -AnnotationAssertion( "inhibition of granulocyte differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030853") -AnnotationAssertion(rdfs:label "negative regulation of granulocyte differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of granulocyte differentiation) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of granulocyte differentiation.") -AnnotationAssertion( "up regulation of granulocyte differentiation") -AnnotationAssertion( "up-regulation of granulocyte differentiation") -AnnotationAssertion( "upregulation of granulocyte differentiation") -AnnotationAssertion( "activation of granulocyte differentiation") -AnnotationAssertion( "stimulation of granulocyte differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030854") -AnnotationAssertion(rdfs:label "positive regulation of granulocyte differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (epithelial cell differentiation) AnnotationAssertion(Annotation( "GOC:ecd") Annotation( "PMID:11839751") "The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell, any of the cells making up an epithelium.") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0030855") AnnotationAssertion(rdfs:label "epithelial cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (regulation of epithelial cell differentiation) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of epithelial cell differentiation.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030856") -AnnotationAssertion(rdfs:label "regulation of epithelial cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of epithelial cell differentiation) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of epithelial cell differentiation.") -AnnotationAssertion( "down regulation of epithelial cell differentiation") -AnnotationAssertion( "down-regulation of epithelial cell differentiation") -AnnotationAssertion( "downregulation of epithelial cell differentiation") -AnnotationAssertion( "inhibition of epithelial cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030857") -AnnotationAssertion(rdfs:label "negative regulation of epithelial cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of epithelial cell differentiation) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of epithelial cell differentiation.") -AnnotationAssertion( "up regulation of epithelial cell differentiation") -AnnotationAssertion( "up-regulation of epithelial cell differentiation") -AnnotationAssertion( "upregulation of epithelial cell differentiation") -AnnotationAssertion( "activation of epithelial cell differentiation") -AnnotationAssertion( "stimulation of epithelial cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030858") -AnnotationAssertion(rdfs:label "positive regulation of epithelial cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (thyroid gland development) - -AnnotationAssertion(Annotation( "GOC:dgh") "The process whose specific outcome is the progression of the thyroid gland over time, from its formation to the mature structure. The thyroid gland is an endoderm-derived gland that produces thyroid hormone.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030878") -AnnotationAssertion(rdfs:label "thyroid gland development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (mammary gland development) AnnotationAssertion(Annotation( "PMID:9576833") "The process whose specific outcome is the progression of the mammary gland over time, from its formation to the mature structure. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk. Its development starts with the formation of the mammary line and ends as the mature gland cycles between nursing and weaning stages.") @@ -71844,209 +23974,10 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:0030879") AnnotationAssertion(rdfs:label "mammary gland development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectAllValuesFrom( )) -# Class: (regulation of myeloid dendritic cell activation) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency or rate of myeloid dendritic cell activation.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030885") -AnnotationAssertion(rdfs:label "regulation of myeloid dendritic cell activation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of myeloid dendritic cell activation) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of myeloid dendritic cell activation.") -AnnotationAssertion( "down regulation of myeloid dendritic cell activation") -AnnotationAssertion( "down-regulation of myeloid dendritic cell activation") -AnnotationAssertion( "downregulation of myeloid dendritic cell activation") -AnnotationAssertion( "inhibition of myeloid dendritic cell activation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030886") -AnnotationAssertion(rdfs:label "negative regulation of myeloid dendritic cell activation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of myeloid dendritic cell activation) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that stimulates, induces or increases the rate of myeloid dendritic cell activation.") -AnnotationAssertion( "up regulation of myeloid dendritic cell activation") -AnnotationAssertion( "up-regulation of myeloid dendritic cell activation") -AnnotationAssertion( "upregulation of myeloid dendritic cell activation") -AnnotationAssertion( "activation of myeloid dendritic cell activation") -AnnotationAssertion( "stimulation of myeloid dendritic cell activation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030887") -AnnotationAssertion(rdfs:label "positive regulation of myeloid dendritic cell activation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of B cell proliferation) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of B cell proliferation.") -AnnotationAssertion( "regulation of B lymphocyte proliferation") -AnnotationAssertion( "regulation of B-cell proliferation") -AnnotationAssertion( "regulation of B-lymphocyte proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030888") -AnnotationAssertion(rdfs:label "regulation of B cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of B cell proliferation) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents or reduces the rate or extent of B cell proliferation.") -AnnotationAssertion( "down regulation of B cell proliferation") -AnnotationAssertion( "down-regulation of B cell proliferation") -AnnotationAssertion( "downregulation of B cell proliferation") -AnnotationAssertion( "negative regulation of B lymphocyte proliferation") -AnnotationAssertion( "negative regulation of B-cell proliferation") -AnnotationAssertion( "negative regulation of B-lymphocyte proliferation") -AnnotationAssertion( "inhibition of B cell proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030889") -AnnotationAssertion(rdfs:label "negative regulation of B cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of B cell proliferation) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the rate or extent of B cell proliferation.") -AnnotationAssertion( "positive regulation of B lymphocyte proliferation") -AnnotationAssertion( "positive regulation of B-cell proliferation") -AnnotationAssertion( "positive regulation of B-lymphocyte proliferation") -AnnotationAssertion( "up regulation of B cell proliferation") -AnnotationAssertion( "up-regulation of B cell proliferation") -AnnotationAssertion( "upregulation of B cell proliferation") -AnnotationAssertion( "activation of B cell proliferation") -AnnotationAssertion( "stimulation of B cell proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030890") -AnnotationAssertion(rdfs:label "positive regulation of B cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (forebrain development) - -AnnotationAssertion(Annotation( "http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=forebrain") "The process whose specific outcome is the progression of the forebrain over time, from its formation to the mature structure. The forebrain is the anterior of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes especially the cerebral hemispheres, the thalamus, and the hypothalamus and especially in higher vertebrates is the main control center for sensory and associative information processing, visceral functions, and voluntary motor functions).") -AnnotationAssertion( "prosencephalon development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030900") -AnnotationAssertion(rdfs:label "forebrain development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (midbrain development) - -AnnotationAssertion(Annotation( "http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=midbrain") "The process whose specific outcome is the progression of the midbrain over time, from its formation to the mature structure. The midbrain is the middle division of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes a ventral part containing the cerebral peduncles and a dorsal tectum containing the corpora quadrigemina and that surrounds the aqueduct of Sylvius connecting the third and fourth ventricles).") -AnnotationAssertion( "mesencephalon development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030901") -AnnotationAssertion(rdfs:label "midbrain development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (hindbrain development) - -AnnotationAssertion(Annotation( "http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=hindbrain") "The process whose specific outcome is the progression of the hindbrain over time, from its formation to the mature structure. The hindbrain is the posterior of the three primary divisions of the developing chordate brain, or the corresponding part of the adult brain (in vertebrates, includes the cerebellum, pons, and medulla oblongata and controls the autonomic functions and equilibrium).") -AnnotationAssertion( "rhombencephalon development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030902") -AnnotationAssertion(rdfs:label "hindbrain development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (notochord development) - -AnnotationAssertion(Annotation( "GOC:dgh") "The process whose specific outcome is the progression of the notochord over time, from its formation to the mature structure. The notochord is a mesoderm-derived structure located ventral of the developing nerve cord. In vertebrates, the notochord serves as a core around which other mesodermal cells form the vertebrae. In the most primitive chordates, which lack vertebrae, the notochord persists as a substitute for a vertebral column.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030903") -AnnotationAssertion(rdfs:label "notochord development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (olfactory placode formation) - -AnnotationAssertion(Annotation( "GOC:dgh") "The formation of a thickening of the neural ectoderm in the head region of the vertebrate embryo which develops into the olfactory region of the nasal cavity.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030910") -AnnotationAssertion(rdfs:label "olfactory placode formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (otic vesicle formation) - -AnnotationAssertion(Annotation( "GOC:dgh") "The process resulting in the transition of the otic placode into the otic vesicle, a transient embryonic structure formed during development of the vertebrate inner ear.") -AnnotationAssertion( "otocyst biosynthesis") -AnnotationAssertion( "otocyst formation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030916") -AnnotationAssertion(rdfs:label "otic vesicle formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (midbrain-hindbrain boundary development) - -AnnotationAssertion(Annotation( "GOC:dgh") "The process whose specific outcome is the progression of the midbrain-hindbrain boundary over time, from its formation to the mature structure. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages.") -AnnotationAssertion( "MHB development") -AnnotationAssertion( "isthmic organizer development") -AnnotationAssertion( "isthmomesencephalic boundary development") -AnnotationAssertion( "isthmus development") -AnnotationAssertion( "midbrain-hindbrain orgainizer development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030917") -AnnotationAssertion(rdfs:label "midbrain-hindbrain boundary development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (transmembrane collagen trimer) - -AnnotationAssertion(Annotation( "ISBN:0721639976") "Any collagen trimer that passes through a lipid bilayer membrane.") -AnnotationAssertion(Annotation( "ISBN:0198599587") "MACIT") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0030936") -AnnotationAssertion(rdfs:label "transmembrane collagen trimer") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (establishment or maintenance of microtubule cytoskeleton polarity) - -AnnotationAssertion(Annotation( "GOC:mah") "Any cellular process that results in the specification, formation or maintenance of polarized microtubule-based cytoskeletal structures.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0030951") -AnnotationAssertion(rdfs:label "establishment or maintenance of microtubule cytoskeleton polarity") -SubClassOf( ) -SubClassOf( ) - -# Class: (establishment or maintenance of cytoskeleton polarity) - -AnnotationAssertion(Annotation( "GOC:mah") "Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "cytoskeleton polarization") -AnnotationAssertion( "GO:0030952") -AnnotationAssertion(rdfs:label "establishment or maintenance of cytoskeleton polarity") -SubClassOf( ) -SubClassOf( ) - # Class: (intraciliary transport particle) AnnotationAssertion(Annotation( "GOC:cilia") Annotation( "GOC:kmv") Annotation( "PMID:14570576") Annotation( "PMID:22118932") Annotation( "PMID:23945166") "A nonmembrane-bound oligomeric protein complex that participates in bidirectional transport of molecules (cargo) along axonemal microtubules.") @@ -72081,66 +24012,6 @@ SubClassOf( ) DisjointClasses( ) -# Class: (pancreas development) - -AnnotationAssertion(Annotation( "GOC:cvs") "The process whose specific outcome is the progression of the pancreas over time, from its formation to the mature structure. The pancreas is an endoderm derived structure that produces precursors of digestive enzymes and blood glucose regulating hormones.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/23777"^^xsd:anyURI) -AnnotationAssertion( "Wikipedia:Pancreas") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0031016") -AnnotationAssertion(rdfs:label "pancreas development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (exocrine pancreas development) - -AnnotationAssertion(Annotation( "GOC:cvs") "The process whose specific outcome is the progression of the exocrine pancreas over time, from its formation to the mature structure. The exocrine pancreas produces and store zymogens of digestive enzymes, such as chymotrypsinogen and trypsinogen in the acinar cells.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0031017") -AnnotationAssertion(rdfs:label "exocrine pancreas development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (endocrine pancreas development) - -AnnotationAssertion(Annotation( "GOC:cvs") "The process whose specific outcome is the progression of the endocrine pancreas over time, from its formation to the mature structure. The endocrine pancreas is made up of islet cells that produce insulin, glucagon and somatostatin.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0031018") -AnnotationAssertion(rdfs:label "endocrine pancreas development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (nuclear migration along microfilament) - -AnnotationAssertion(Annotation( "GOC:mah") "The directed movement of the nucleus along microfilaments within the cell, mediated by motor proteins.") -AnnotationAssertion( "nuclear migration, microfilament-mediated") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0031022") -AnnotationAssertion(rdfs:label "nuclear migration along microfilament") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (actomyosin structure organization) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:jl") Annotation( "GOC:mah") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures containing both actin and myosin or paramyosin. The myosin may be organized into filaments.") -AnnotationAssertion( "actomyosin organization") -AnnotationAssertion( "actomyosin structure organisation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:mah") "actomyosin structure organization and biogenesis") -AnnotationAssertion( "GO:0031032") -AnnotationAssertion(rdfs:comment "Note that this term is a child of 'actin cytoskeleton organization and biogenesis ; GO:0030036' because the actin cytoskeleton is defined as actin filaments and associated proteins.") -AnnotationAssertion(rdfs:label "actomyosin structure organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - # Class: (dense core granule) AnnotationAssertion(Annotation( "NIF_Subcellular:sao772007592") Annotation( "PMID:14690495") "Electron-dense organelle with a granular internal matrix; contains proteins destined to be secreted.") @@ -72151,39 +24022,6 @@ AnnotationAssertion( "dense core granule") SubClassOf( ) -# Class: (hair follicle morphogenesis) - -AnnotationAssertion(Annotation( "GOC:ln") "The process in which the anatomical structures of the hair follicle are generated and organized.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0031069") -AnnotationAssertion(rdfs:label "hair follicle morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (embryonic camera-type eye development) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:mtg_sensu") "The process occurring during the embryonic phase whose specific outcome is the progression of the eye over time, from its formation to the mature structure.") -AnnotationAssertion( "embryonic eye development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0031076") -AnnotationAssertion(rdfs:label "embryonic camera-type eye development") -SubClassOf( ) -SubClassOf( ) - -# Class: (organelle membrane) - -AnnotationAssertion(Annotation( "GOC:dos") Annotation( "GOC:mah") "A membrane that is one of the two lipid bilayers of an organelle envelope or the outermost membrane of single membrane bound organelle.") -AnnotationAssertion( "NIF_Subcellular:sao830981606") -AnnotationAssertion( "cellular_component") -AnnotationAssertion(Annotation( "NIF_Subcellular:sao830981606") "intracellular membrane") -AnnotationAssertion( "GO:0031090") -AnnotationAssertion(rdfs:label "organelle membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (regeneration) AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:pr") "The regrowth of a lost or destroyed body part, such as an organ or tissue. This process may occur via renewal, repair, and/or growth alone (i.e. increase in size or mass).") @@ -72194,181 +24032,6 @@ AnnotationAssertion(rdfs:label "rege SubClassOf( ) SubClassOf( ) -# Class: (animal organ regeneration) - -AnnotationAssertion(Annotation( "GOC:mah") "The regrowth of a lost or destroyed animal organ.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0031100") -AnnotationAssertion(rdfs:label "animal organ regeneration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (fin regeneration) - -AnnotationAssertion(Annotation( "GOC:dgh") "The regrowth of fin tissue following its loss or destruction.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0031101") -AnnotationAssertion(rdfs:label "fin regeneration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (microtubule polymerization or depolymerization) - -AnnotationAssertion(Annotation( "GOC:mah") "Assembly or disassembly of microtubules by the addition or removal of tubulin heterodimers from a microtubule.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/23195"^^xsd:anyURI) -AnnotationAssertion( "microtubule dynamics") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0031109") -AnnotationAssertion(rdfs:label "microtubule polymerization or depolymerization") -SubClassOf( ) - -# Class: (regulation of microtubule polymerization or depolymerization) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of microtubule polymerization or depolymerization by the addition or removal of tubulin heterodimers from a microtubule.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0031110") -AnnotationAssertion(rdfs:label "regulation of microtubule polymerization or depolymerization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of microtubule polymerization or depolymerization) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule polymerization or depolymerization.") -AnnotationAssertion( "down regulation of microtubule polymerization or depolymerization") -AnnotationAssertion( "down-regulation of microtubule polymerization or depolymerization") -AnnotationAssertion( "downregulation of microtubule polymerization or depolymerization") -AnnotationAssertion( "inhibition of microtubule polymerization or depolymerization") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0031111") -AnnotationAssertion(rdfs:label "negative regulation of microtubule polymerization or depolymerization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of microtubule polymerization or depolymerization) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of microtubule polymerization or depolymerization.") -AnnotationAssertion( "up regulation of microtubule polymerization or depolymerization") -AnnotationAssertion( "up-regulation of microtubule polymerization or depolymerization") -AnnotationAssertion( "upregulation of microtubule polymerization or depolymerization") -AnnotationAssertion( "activation of microtubule polymerization or depolymerization") -AnnotationAssertion( "stimulation of microtubule polymerization or depolymerization") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0031112") -AnnotationAssertion(rdfs:label "positive regulation of microtubule polymerization or depolymerization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of microtubule polymerization) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of microtubule polymerization.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0031113") -AnnotationAssertion(rdfs:label "regulation of microtubule polymerization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of microtubule depolymerization) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of microtubule depolymerization.") -AnnotationAssertion( "regulation of microtubule disassembly") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0031114") -AnnotationAssertion(rdfs:label "regulation of microtubule depolymerization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of microtubule polymerization) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule polymerization.") -AnnotationAssertion( "down regulation of microtubule polymerization") -AnnotationAssertion( "down-regulation of microtubule polymerization") -AnnotationAssertion( "downregulation of microtubule polymerization") -AnnotationAssertion( "inhibition of microtubule polymerization") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0031115") -AnnotationAssertion(rdfs:label "negative regulation of microtubule polymerization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of microtubule polymerization) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of microtubule polymerization.") -AnnotationAssertion( "up regulation of microtubule polymerization") -AnnotationAssertion( "up-regulation of microtubule polymerization") -AnnotationAssertion( "upregulation of microtubule polymerization") -AnnotationAssertion( "activation of microtubule polymerization") -AnnotationAssertion( "stimulation of microtubule polymerization") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0031116") -AnnotationAssertion(rdfs:label "positive regulation of microtubule polymerization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of microtubule depolymerization) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of microtubule depolymerization.") -AnnotationAssertion( "microtubule destabilization") -AnnotationAssertion( "positive regulation of microtubule disassembly") -AnnotationAssertion( "up regulation of microtubule depolymerization") -AnnotationAssertion( "up-regulation of microtubule depolymerization") -AnnotationAssertion( "upregulation of microtubule depolymerization") -AnnotationAssertion( "activation of microtubule depolymerization") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "positive regulation of microtubule catastrophe") -AnnotationAssertion( "stimulation of microtubule depolymerization") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0031117") -AnnotationAssertion(rdfs:label "positive regulation of microtubule depolymerization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cytoplasmic microtubule organization) - -AnnotationAssertion(Annotation( "GOC:mah") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures formed of microtubules and associated proteins in the cytoplasm of a cell.") -AnnotationAssertion( "cytoplasmic microtubule organisation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:mah") "cytoplasmic microtubule organization and biogenesis") -AnnotationAssertion( "GO:0031122") -AnnotationAssertion(rdfs:label "cytoplasmic microtubule organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (developmental induction) - -AnnotationAssertion(Annotation( "GOC:cjm") Annotation( "GOC:dph") Annotation( "GOC:mah") Annotation( "PMID:24503535") "A developmental process involving two tissues in which one tissue (the inducer) produces a signal that directs cell fate commitment of cells in the second tissue (the responder).") -AnnotationAssertion( ) -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0031128") -AnnotationAssertion(rdfs:label "developmental induction") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) -DisjointClasses( ObjectSomeValuesFrom( )) - -# Class: (pseudopodium) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "A temporary protrusion or retractile process of a cell, associated with flowing movements of the protoplasm, and serving for locomotion and feeding.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/21139"^^xsd:anyURI) -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/21141"^^xsd:anyURI) -AnnotationAssertion( "Wikipedia:Pseudopod") -AnnotationAssertion( "pseudopod") -AnnotationAssertion( "pseudopodial protrusion") -AnnotationAssertion( "axopodium") -AnnotationAssertion( "lobopodium") -AnnotationAssertion( "reticulopodium") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0031143") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "pseudopodium") -SubClassOf( ) - -# Class: (neuron projection development) - -AnnotationAssertion(Annotation( "GOC:mah") "The process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).") -AnnotationAssertion( "neurite biosynthesis") -AnnotationAssertion(Annotation( "GOC:dph") "neurite development") -AnnotationAssertion( "neurite formation") -AnnotationAssertion( "neurite growth") -AnnotationAssertion( "neurite outgrowth") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0031175") -AnnotationAssertion(rdfs:label "neuron projection development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (biomineral tissue development) AnnotationAssertion(Annotation( "PMID:15132736") "Formation of hard tissues that consist mainly of inorganic compounds, and also contain a small amounts of organic matrices that are believed to play important roles in their formation.") @@ -72379,463 +24042,6 @@ AnnotationAssertion(rdfs:label "biom SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (cell leading edge) - -AnnotationAssertion(Annotation( "GOC:pg") "The area of a motile cell closest to the direction of movement.") -AnnotationAssertion( "front of cell") -AnnotationAssertion( "leading edge of cell") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0031252") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "cell leading edge") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cell projection membrane) - -AnnotationAssertion(Annotation( "GOC:krc") Annotation( "GOC:mah") "The portion of the plasma membrane surrounding a plasma membrane bounded cell surface projection.") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "membrane extension") -AnnotationAssertion( "membrane projection") -AnnotationAssertion( "GO:0031253") -AnnotationAssertion(rdfs:label "cell projection membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (leading edge membrane) - -AnnotationAssertion(Annotation( "GOC:mah") "The portion of the plasma membrane surrounding the leading edge of a motile cell.") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0031256") -AnnotationAssertion(rdfs:label "leading edge membrane") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (pseudopodium organization) - -AnnotationAssertion(Annotation( "GOC:pg") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a pseudopodium, a temporary protrusion or retractile process of a cell, associated with cellular movement.") -AnnotationAssertion( "pseudopodium organisation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:mah") "pseudopodium organization and biogenesis") -AnnotationAssertion( "GO:0031268") -AnnotationAssertion(rdfs:label "pseudopodium organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (pseudopodium assembly) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mah") Annotation( "GOC:pg") Annotation( "GOC:tb") "The assembly of a pseudopodium by rearrangement of the actin cytoskeleton and overlying membrane.") -AnnotationAssertion( "pseudopodium extension") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "pseudopodium formation") -AnnotationAssertion( "GO:0031269") -AnnotationAssertion(rdfs:label "pseudopodium assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (pseudopodium retraction) - -AnnotationAssertion(Annotation( "GOC:pg") "The myosin-based contraction and retraction of a pseudopodium.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0031270") -AnnotationAssertion(rdfs:label "pseudopodium retraction") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of pseudopodium assembly) - -AnnotationAssertion(Annotation( "GOC:pg") "Any process that modulates the frequency, rate or extent of the assembly of pseudopodia.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "regulation of pseudopodium formation") -AnnotationAssertion( "GO:0031272") -AnnotationAssertion(rdfs:label "regulation of pseudopodium assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of pseudopodium assembly) - -AnnotationAssertion(Annotation( "GOC:pg") "Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly of pseudopodia.") -AnnotationAssertion( "inhibition of pseudopodium formation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "down regulation of pseudopodium formation") -AnnotationAssertion( "down-regulation of pseudopodium formation") -AnnotationAssertion( "downregulation of pseudopodium formation") -AnnotationAssertion( "negative regulation of pseudopodium formation") -AnnotationAssertion( "GO:0031273") -AnnotationAssertion(rdfs:label "negative regulation of pseudopodium assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of pseudopodium assembly) - -AnnotationAssertion(Annotation( "GOC:pg") "Any process that activates or increases the frequency, rate or extent of the assembly of pseudopodia.") -AnnotationAssertion( "activation of pseudopodium formation") -AnnotationAssertion( "stimulation of pseudopodium formation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") "positive regulation of pseudopodium formation") -AnnotationAssertion( "up regulation of pseudopodium formation") -AnnotationAssertion( "up-regulation of pseudopodium formation") -AnnotationAssertion( "upregulation of pseudopodium formation") -AnnotationAssertion( "GO:0031274") -AnnotationAssertion(rdfs:label "positive regulation of pseudopodium assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of cellular metabolic process) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances.") -AnnotationAssertion( "regulation of cellular metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0031323") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "regulation of cellular metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of cellular metabolic process) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances.") -AnnotationAssertion( "down regulation of cellular metabolic process") -AnnotationAssertion( "down-regulation of cellular metabolic process") -AnnotationAssertion( "downregulation of cellular metabolic process") -AnnotationAssertion( "negative regulation of cellular metabolism") -AnnotationAssertion( "inhibition of cellular metabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0031324") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "negative regulation of cellular metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of cellular metabolic process) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances.") -AnnotationAssertion( "positive regulation of cellular metabolism") -AnnotationAssertion( "up regulation of cellular metabolic process") -AnnotationAssertion( "up-regulation of cellular metabolic process") -AnnotationAssertion( "upregulation of cellular metabolic process") -AnnotationAssertion( "activation of cellular metabolic process") -AnnotationAssertion( "stimulation of cellular metabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0031325") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "positive regulation of cellular metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of cellular biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.") -AnnotationAssertion( "regulation of cellular anabolism") -AnnotationAssertion( "regulation of cellular biosynthesis") -AnnotationAssertion( "regulation of cellular formation") -AnnotationAssertion( "regulation of cellular synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0031326") -AnnotationAssertion(rdfs:label "regulation of cellular biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of cellular biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.") -AnnotationAssertion( "down regulation of cellular biosynthetic process") -AnnotationAssertion( "down-regulation of cellular biosynthetic process") -AnnotationAssertion( "downregulation of cellular biosynthetic process") -AnnotationAssertion( "negative regulation of cellular anabolism") -AnnotationAssertion( "negative regulation of cellular biosynthesis") -AnnotationAssertion( "negative regulation of cellular formation") -AnnotationAssertion( "negative regulation of cellular synthesis") -AnnotationAssertion( "inhibition of cellular biosynthetic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0031327") -AnnotationAssertion(rdfs:label "negative regulation of cellular biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of cellular biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.") -AnnotationAssertion( "positive regulation of cellular anabolism") -AnnotationAssertion( "positive regulation of cellular biosynthesis") -AnnotationAssertion( "positive regulation of cellular formation") -AnnotationAssertion( "positive regulation of cellular synthesis") -AnnotationAssertion( "up regulation of cellular biosynthetic process") -AnnotationAssertion( "up-regulation of cellular biosynthetic process") -AnnotationAssertion( "upregulation of cellular biosynthetic process") -AnnotationAssertion( "activation of cellular biosynthetic process") -AnnotationAssertion( "stimulation of cellular biosynthetic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0031328") -AnnotationAssertion(rdfs:label "positive regulation of cellular biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of cellular catabolic process) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells.") -AnnotationAssertion( "regulation of cellular breakdown") -AnnotationAssertion( "regulation of cellular catabolism") -AnnotationAssertion( "regulation of cellular degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0031329") -AnnotationAssertion(rdfs:label "regulation of cellular catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of cellular catabolic process) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells.") -AnnotationAssertion( "down regulation of cellular catabolic process") -AnnotationAssertion( "down-regulation of cellular catabolic process") -AnnotationAssertion( "downregulation of cellular catabolic process") -AnnotationAssertion( "negative regulation of cellular breakdown") -AnnotationAssertion( "negative regulation of cellular catabolism") -AnnotationAssertion( "negative regulation of cellular degradation") -AnnotationAssertion( "inhibition of cellular catabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0031330") -AnnotationAssertion(rdfs:label "negative regulation of cellular catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of cellular catabolic process) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells.") -AnnotationAssertion( "positive regulation of cellular breakdown") -AnnotationAssertion( "positive regulation of cellular catabolism") -AnnotationAssertion( "positive regulation of cellular degradation") -AnnotationAssertion( "up regulation of cellular catabolic process") -AnnotationAssertion( "up-regulation of cellular catabolic process") -AnnotationAssertion( "upregulation of cellular catabolic process") -AnnotationAssertion( "activation of cellular catabolic process") -AnnotationAssertion( "stimulation of cellular catabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0031331") -AnnotationAssertion(rdfs:label "positive regulation of cellular catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of protein-containing complex assembly) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of protein complex assembly.") -AnnotationAssertion( "down regulation of protein complex assembly") -AnnotationAssertion( "down-regulation of protein complex assembly") -AnnotationAssertion( "downregulation of protein complex assembly") -AnnotationAssertion( "inhibition of protein complex assembly") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "negative regulation of protein complex assembly") -AnnotationAssertion( "GO:0031333") -AnnotationAssertion(rdfs:label "negative regulation of protein-containing complex assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of protein-containing complex assembly) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of protein complex assembly.") -AnnotationAssertion( "up regulation of protein complex assembly") -AnnotationAssertion( "up-regulation of protein complex assembly") -AnnotationAssertion( "upregulation of protein complex assembly") -AnnotationAssertion( "activation of protein complex assembly") -AnnotationAssertion( "stimulation of protein complex assembly") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "positive regulation of protein complex assembly") -AnnotationAssertion( "GO:0031334") -AnnotationAssertion(rdfs:label "positive regulation of protein-containing complex assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (regulation of vesicle fusion) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of vesicle fusion.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0031338") -AnnotationAssertion(rdfs:label "regulation of vesicle fusion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of vesicle fusion) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of vesicle fusion.") -AnnotationAssertion( "down regulation of vesicle fusion") -AnnotationAssertion( "down-regulation of vesicle fusion") -AnnotationAssertion( "downregulation of vesicle fusion") -AnnotationAssertion( "inhibition of vesicle fusion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0031339") -AnnotationAssertion(rdfs:label "negative regulation of vesicle fusion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of vesicle fusion) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of vesicle fusion.") -AnnotationAssertion( "up regulation of vesicle fusion") -AnnotationAssertion( "up-regulation of vesicle fusion") -AnnotationAssertion( "upregulation of vesicle fusion") -AnnotationAssertion( "activation of vesicle fusion") -AnnotationAssertion( "stimulation of vesicle fusion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0031340") -AnnotationAssertion(rdfs:label "positive regulation of vesicle fusion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of cell projection organization) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell projections.") -AnnotationAssertion( "regulation of cell projection organisation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:mah") "regulation of cell projection organization and biogenesis") -AnnotationAssertion( "GO:0031344") -AnnotationAssertion(rdfs:label "regulation of cell projection organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of cell projection organization) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell projections.") -AnnotationAssertion(Annotation( "GOC:mah") "down regulation of cell projection organization") -AnnotationAssertion( "down-regulation of cell projection organization") -AnnotationAssertion( "downregulation of cell projection organization") -AnnotationAssertion( "negative regulation of cell projection organisation") -AnnotationAssertion( "inhibition of cell projection organization") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:mah") "negative regulation of cell projection organization and biogenesis") -AnnotationAssertion( "GO:0031345") -AnnotationAssertion(rdfs:label "negative regulation of cell projection organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of cell projection organization) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of the process involved in the formation, arrangement of constituent parts, or disassembly of cell projections.") -AnnotationAssertion( "positive regulation of cell projection organisation") -AnnotationAssertion( "up regulation of cell projection organization") -AnnotationAssertion( "up-regulation of cell projection organization") -AnnotationAssertion( "upregulation of cell projection organization") -AnnotationAssertion( "activation of cell projection organization") -AnnotationAssertion( "stimulation of cell projection organization") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:mah") "positive regulation of cell projection organization and biogenesis") -AnnotationAssertion( "GO:0031346") -AnnotationAssertion(rdfs:label "positive regulation of cell projection organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of defense response) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of a defense response.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0031347") -AnnotationAssertion(rdfs:label "regulation of defense response") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (negative regulation of defense response) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of a defense response.") -AnnotationAssertion( "down regulation of defense response") -AnnotationAssertion( "down-regulation of defense response") -AnnotationAssertion( "downregulation of defense response") -AnnotationAssertion( "inhibition of defense response") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0031348") -AnnotationAssertion(rdfs:label "negative regulation of defense response") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of defense response) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of a defense response.") -AnnotationAssertion( "up regulation of defense response") -AnnotationAssertion( "up-regulation of defense response") -AnnotationAssertion( "upregulation of defense response") -AnnotationAssertion( "activation of defense response") -AnnotationAssertion( "stimulation of defense response") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0031349") -AnnotationAssertion(rdfs:label "positive regulation of defense response") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of protein modification process) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:tb") "Any process that modulates the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0031399") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "regulation of protein modification process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of protein modification process) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:tb") "Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein.") -AnnotationAssertion( "down regulation of protein modification") -AnnotationAssertion( "down-regulation of protein modification") -AnnotationAssertion( "downregulation of protein modification") -AnnotationAssertion( "inhibition of protein modification") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0031400") -AnnotationAssertion(rdfs:label "negative regulation of protein modification process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of protein modification process) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:tb") "Any process that activates or increases the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein.") -AnnotationAssertion( "up regulation of protein modification") -AnnotationAssertion( "up-regulation of protein modification") -AnnotationAssertion( "upregulation of protein modification") -AnnotationAssertion( "activation of protein modification") -AnnotationAssertion( "stimulation of protein modification") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0031401") -AnnotationAssertion(rdfs:label "positive regulation of protein modification process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (sodium ion binding) - -AnnotationAssertion(Annotation( "GOC:mah") "Binding to a sodium ion (Na+).") -AnnotationAssertion( "Na+ ion binding") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0031402") -AnnotationAssertion(rdfs:label "sodium ion binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (carboxylic acid binding) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "ISBN:0198506732") "Binding to a carboxylic acid, an organic acid containing one or more carboxyl (COOH) groups or anions (COO-).") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0031406") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "carboxylic acid binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (pigment binding) - -AnnotationAssertion(Annotation( "GOC:mah") "Binding to a pigment, a general or particular coloring matter in living organisms, e.g. melanin.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0031409") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "pigment binding") -SubClassOf( ) - # Class: (cytoplasmic vesicle) AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:mah") Annotation( "GOC:vesicles") "A vesicle found in the cytoplasm of a cell.") @@ -72853,7 +24059,6 @@ AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "cytoplasmic vesicle") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) @@ -72864,15 +24069,6 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0031413") AnnotationAssertion(rdfs:label "regulation of buoyancy") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (alkali metal ion binding) - -AnnotationAssertion(Annotation( "GOC:mah") "Binding to an alkali metal ion; alkali metals are those elements in group Ia of the periodic table, with the exception of hydrogen.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0031420") -AnnotationAssertion(rdfs:label "alkali metal ion binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (keratinization) @@ -72884,360 +24080,6 @@ SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (protein-containing complex localization) - -AnnotationAssertion(Annotation( "GOC:mah") "A localization process that acts on a protein complex; the complex is transported to, or maintained in, a specific location.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/22021"^^xsd:anyURI) -AnnotationAssertion( "GO:0034629") -AnnotationAssertion( "establishment and maintenance of protein complex localization") -AnnotationAssertion(Annotation( "GOC:mah") "protein complex localisation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:mah") "cellular protein complex localisation") -AnnotationAssertion( "cellular protein complex localization") -AnnotationAssertion( "cellular protein-containing complex localization") -AnnotationAssertion( "establishment and maintenance of cellular protein complex localization") -AnnotationAssertion( "protein complex localization") -AnnotationAssertion( "GO:0031503") -AnnotationAssertion(rdfs:label "protein-containing complex localization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (motile cilium) - -AnnotationAssertion(Annotation( "GOC:cilia") Annotation( "GOC:dgh") Annotation( "GOC:kmv") Annotation( "PMID:17009929") Annotation( "PMID:20144998") Annotation( "PMID:22118931") "A cilium which may have a variable arrangement of axonemal microtubules and also contains molecular motors. It may beat with a whip-like pattern that promotes cell motility or transport of fluids and other cells across a cell surface, such as on epithelial cells that line the lumenal ducts of various tissues; or they may display a distinct twirling motion that directs fluid flow asymmetrically across the cellular surface to affect asymmetric body plan organization. Motile cilia can be found in single as well as multiple copies per cell.") -AnnotationAssertion( "GO:0009434") -AnnotationAssertion( "GO:0031512") -AnnotationAssertion( "motile cilia") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "microtubule-based flagellum") -AnnotationAssertion( "motile primary cilia") -AnnotationAssertion( "motile primary cilium") -AnnotationAssertion( "motile secondary cilium") -AnnotationAssertion( "nodal cilium") -AnnotationAssertion( "GO:0031514") -AnnotationAssertion(rdfs:label "motile cilium") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (neuromuscular junction) - -AnnotationAssertion(Annotation( "GOC:nln") "The junction between the axon of a motor neuron and a muscle fiber. In response to the arrival of action potentials, the presynaptic button releases molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane of the muscle fiber, leading to a change in post-synaptic potential.") -AnnotationAssertion( "NIF_Subcellular:sao1124888485") -AnnotationAssertion( "Wikipedia:Neuromuscular_junction") -AnnotationAssertion( "cellular_component") -AnnotationAssertion(Annotation( "GOC:ha") "NMJ") -AnnotationAssertion(Annotation( "NIF_Subcellular:nlx_subcell_20090512") "motor endplate") -AnnotationAssertion( "GO:0031594") -AnnotationAssertion(rdfs:comment "In vertebrates, the term 'neuromuscular junction' is limited to synapses targeting skeletal muscle fibers - all of which are cholinergic and excitatory. Both inhibitory and excitatory neuromuscular junctions exist in invertebrates, utilizing a range of neurotransmitters including glutamate, GABA and 5-HT.") -AnnotationAssertion(rdfs:label "neuromuscular junction") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of myelination) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the formation of a myelin sheath around nerve axons.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0031641") -AnnotationAssertion(rdfs:label "regulation of myelination") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (negative regulation of myelination) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of the formation of a myelin sheath around nerve axons.") -AnnotationAssertion( "down regulation of myelination") -AnnotationAssertion( "down-regulation of myelination") -AnnotationAssertion( "downregulation of myelination") -AnnotationAssertion( "inhibition of myelination") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0031642") -AnnotationAssertion(rdfs:label "negative regulation of myelination") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (positive regulation of myelination) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of the formation of a myelin sheath around nerve axons.") -AnnotationAssertion( "up regulation of myelination") -AnnotationAssertion( "up-regulation of myelination") -AnnotationAssertion( "upregulation of myelination") -AnnotationAssertion( "activation of myelination") -AnnotationAssertion( "stimulation of myelination") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0031643") -AnnotationAssertion(rdfs:label "positive regulation of myelination") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of nervous system process) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mah") Annotation( "GOC:tb") "Any process that modulates the frequency, rate or extent of a neurophysiological process, an organ system process carried out by any of the organs or tissues of the nervous system.") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "regulation of neurological process") -AnnotationAssertion( "regulation of neurological system process") -AnnotationAssertion( "regulation of neurophysiological process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0031644") -AnnotationAssertion(rdfs:label "regulation of nervous system process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (negative regulation of nervous system process) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mah") Annotation( "GOC:tb") "Any process that stops, prevents, or reduces the frequency, rate or extent of a neurophysiological process.") -AnnotationAssertion( "down regulation of neurological process") -AnnotationAssertion( "down-regulation of neurological process") -AnnotationAssertion( "downregulation of neurological process") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "negative regulation of neurological process") -AnnotationAssertion( "negative regulation of neurological system process") -AnnotationAssertion( "negative regulation of neurophysiological process") -AnnotationAssertion( "inhibition of neurological process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0031645") -AnnotationAssertion(rdfs:label "negative regulation of nervous system process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (positive regulation of nervous system process) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mah") Annotation( "GOC:tb") "Any process that activates or increases the frequency, rate or extent of a neurophysiological process.") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "positive regulation of neurological process") -AnnotationAssertion( "positive regulation of neurological system process") -AnnotationAssertion( "positive regulation of neurophysiological process") -AnnotationAssertion( "up regulation of neurological process") -AnnotationAssertion( "up-regulation of neurological process") -AnnotationAssertion( "upregulation of neurological process") -AnnotationAssertion( "activation of neurological process") -AnnotationAssertion( "stimulation of neurological process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0031646") -AnnotationAssertion(rdfs:label "positive regulation of nervous system process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (CCR2 chemokine receptor binding) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:nln") "Binding to a CCR2 chemokine receptor.") -AnnotationAssertion( "monocyte chemoattractant protein 1 receptor binding") -AnnotationAssertion( "CCR2 chemokine receptor ligand") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0031727") -AnnotationAssertion(rdfs:label "CCR2 chemokine receptor binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (CX3C chemokine receptor binding) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:nln") "Binding to a CX3C chemokine receptor.") -AnnotationAssertion( "fractalkine receptor binding") -AnnotationAssertion( "CX3C chemokine receptor ligand") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0031737") -AnnotationAssertion(rdfs:label "CX3C chemokine receptor binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of glucocorticoid metabolic process) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving glucocorticoids.") -AnnotationAssertion( "regulation of glucocorticoid metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0031943") -AnnotationAssertion(rdfs:label "regulation of glucocorticoid metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of glucocorticoid metabolic process) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving glucocorticoids.") -AnnotationAssertion( "down regulation of glucocorticoid metabolic process") -AnnotationAssertion( "down-regulation of glucocorticoid metabolic process") -AnnotationAssertion( "downregulation of glucocorticoid metabolic process") -AnnotationAssertion( "negative regulation of glucocorticoid metabolism") -AnnotationAssertion( "inhibition of glucocorticoid metabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0031944") -AnnotationAssertion(rdfs:label "negative regulation of glucocorticoid metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of glucocorticoid metabolic process) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving glucocorticoids.") -AnnotationAssertion( "positive regulation of glucocorticoid metabolism") -AnnotationAssertion( "up regulation of glucocorticoid metabolic process") -AnnotationAssertion( "up-regulation of glucocorticoid metabolic process") -AnnotationAssertion( "upregulation of glucocorticoid metabolic process") -AnnotationAssertion( "activation of glucocorticoid metabolic process") -AnnotationAssertion( "stimulation of glucocorticoid metabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0031945") -AnnotationAssertion(rdfs:label "positive regulation of glucocorticoid metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of glucocorticoid biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucocorticoids.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0031946") -AnnotationAssertion(rdfs:label "regulation of glucocorticoid biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of glucocorticoid biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucocorticoids.") -AnnotationAssertion( "down regulation of glucocorticoid biosynthetic process") -AnnotationAssertion( "down-regulation of glucocorticoid biosynthetic process") -AnnotationAssertion( "downregulation of glucocorticoid biosynthetic process") -AnnotationAssertion( "inhibition of glucocorticoid biosynthetic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0031947") -AnnotationAssertion(rdfs:label "negative regulation of glucocorticoid biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of glucocorticoid biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucocorticoids.") -AnnotationAssertion( "up regulation of glucocorticoid biosynthetic process") -AnnotationAssertion( "up-regulation of glucocorticoid biosynthetic process") -AnnotationAssertion( "upregulation of glucocorticoid biosynthetic process") -AnnotationAssertion( "activation of glucocorticoid biosynthetic process") -AnnotationAssertion( "stimulation of glucocorticoid biosynthetic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0031948") -AnnotationAssertion(rdfs:label "positive regulation of glucocorticoid biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of glucocorticoid catabolic process) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glucocorticoids.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0031949") -AnnotationAssertion(rdfs:label "regulation of glucocorticoid catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (negative regulation of glucocorticoid catabolic process) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glucocorticoids.") -AnnotationAssertion( "down regulation of glucocorticoid catabolic process") -AnnotationAssertion( "down-regulation of glucocorticoid catabolic process") -AnnotationAssertion( "downregulation of glucocorticoid catabolic process") -AnnotationAssertion( "inhibition of glucocorticoid catabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0031950") -AnnotationAssertion(rdfs:label "negative regulation of glucocorticoid catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (positive regulation of glucocorticoid catabolic process) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glucocorticoids.") -AnnotationAssertion( "up regulation of glucocorticoid catabolic process") -AnnotationAssertion( "up-regulation of glucocorticoid catabolic process") -AnnotationAssertion( "upregulation of glucocorticoid catabolic process") -AnnotationAssertion( "activation of glucocorticoid catabolic process") -AnnotationAssertion( "stimulation of glucocorticoid catabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0031951") -AnnotationAssertion(rdfs:label "positive regulation of glucocorticoid catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (corticosteroid receptor signaling pathway) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "PMID:11027914") Annotation( "PMID:12606724") "The series of molecular signals initiated by corticosteroid binding to its receptor, and ending with the regulation of a downstream cellular process, e.g. transcription.") -AnnotationAssertion( "corticosteroid receptor signalling pathway") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0031958") -AnnotationAssertion(rdfs:label "corticosteroid receptor signaling pathway") -SubClassOf( ) -SubClassOf( ) - -# Class: (response to corticosteroid) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "PMID:11027914") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticosteroid hormone stimulus. A corticosteroid is a steroid hormone that is produced in the adrenal cortex. Corticosteroids are involved in a wide range of physiologic systems such as stress response, immune response and regulation of inflammation, carbohydrate metabolism, protein catabolism, blood electrolyte levels, and behavior. They include glucocorticoids and mineralocorticoids.") -AnnotationAssertion(Annotation( "GOC:dos") "response to corticosteroid stimulus") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0031960") -AnnotationAssertion(rdfs:label "response to corticosteroid") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (nuclear membrane) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:pz") "Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space.") -AnnotationAssertion( "NIF_Subcellular:sao1687101204") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0031965") -AnnotationAssertion(rdfs:label "nuclear membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (organelle envelope) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:pz") "A double membrane structure enclosing an organelle, including two lipid bilayers and the region between them. In some cases, an organelle envelope may have more than two membranes.") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0031967") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "organelle envelope") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (organelle outer membrane) - -AnnotationAssertion(Annotation( "GOC:mah") "The outer, i.e. cytoplasm-facing in a cellular organelle, lipid bilayer of an organelle envelope.") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0031968") -AnnotationAssertion(rdfs:label "organelle outer membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (membrane-enclosed lumen) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:mah") "The enclosed volume within a sealed membrane or between two sealed membranes. Encompasses the volume enclosed by the membranes of a particular organelle, e.g. endoplasmic reticulum lumen, or the space between the two lipid bilayers of a double membrane surrounding an organelle, e.g. nuclear envelope lumen.") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0031974") -AnnotationAssertion(rdfs:label "membrane-enclosed lumen") -SubClassOf( ) -DisjointClasses( ) - -# Class: (envelope) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:pz") "A multilayered structure surrounding all or part of a cell; encompasses one or more lipid bilayers, and may include a cell wall layer; also includes the space between layers.") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0031975") -AnnotationAssertion(rdfs:label "envelope") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (nuclear lumen) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:pz") "The volume enclosed by the nuclear inner membrane.") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0031981") -AnnotationAssertion(rdfs:label "nuclear lumen") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (vesicle) AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:pz") Annotation( "GOC:vesicles") "Any small, fluid-filled, spherical organelle enclosed by membrane.") @@ -73252,765 +24094,6 @@ AnnotationAssertion( "vesicle") SubClassOf( ) -# Class: (locomotion involved in locomotory behavior) - -AnnotationAssertion(Annotation( "GOC:mah") "Self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement.") -AnnotationAssertion( "locomotion during locomotory behaviour") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0031987") -AnnotationAssertion(rdfs:label "locomotion involved in locomotory behavior") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (positive regulation of insulin secretion) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of the regulated release of insulin.") -AnnotationAssertion( "up regulation of insulin secretion") -AnnotationAssertion( "up-regulation of insulin secretion") -AnnotationAssertion( "upregulation of insulin secretion") -AnnotationAssertion( "activation of insulin secretion") -AnnotationAssertion( "stimulation of insulin secretion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032024") -AnnotationAssertion(rdfs:label "positive regulation of insulin secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (bile acid binding) - -AnnotationAssertion(Annotation( "GOC:rph") "Binding to a bile acid, a steroid carboxylic acids occurring in bile.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0032052") -AnnotationAssertion(rdfs:label "bile acid binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of translational initiation in response to stress) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents or reduces the rate of translation initiation as a result of a stimulus indicating the organism is under stress.") -AnnotationAssertion( "down regulation of translation initiation in response to stress") -AnnotationAssertion( "down-regulation of translation initiation in response to stress") -AnnotationAssertion( "downregulation of translation initiation in response to stress") -AnnotationAssertion( "inhibition of translation initiation in response to stress") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032057") -AnnotationAssertion(rdfs:label "negative regulation of translational initiation in response to stress") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of translational initiation in response to stress) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of translation initiation as a result of a stimulus indicating the organism is under stress.") -AnnotationAssertion( "up regulation of translation initiation in response to stress") -AnnotationAssertion( "up-regulation of translation initiation in response to stress") -AnnotationAssertion( "upregulation of translation initiation in response to stress") -AnnotationAssertion( "activation of translation initiation in response to stress") -AnnotationAssertion( "stimulation of translation initiation in response to stress") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032058") -AnnotationAssertion(rdfs:label "positive regulation of translational initiation in response to stress") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (bleb) - -AnnotationAssertion(Annotation( "GOC:mtg_apoptosis") Annotation( "PMID:12083798") Annotation( "PMID:16624291") Annotation( "Wikipedia:Bleb_(cell_biology)") "A cell extension caused by localized decoupling of the cytoskeleton from the plasma membrane and characterized by rapid formation, rounded shape, and scarcity of organelles within the protrusion. Blebs are formed during apoptosis and other cellular processes, including cell locomotion, cell division, and as a result of physical or chemical stresses.") -AnnotationAssertion( "Wikipedia:Bleb_(cell_biology)") -AnnotationAssertion(Annotation( "GOC:pr") "plasma membrane bleb") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0032059") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "bleb") -SubClassOf( ) - -# Class: (bleb assembly) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:mtg_apoptosis") Annotation( "PMID:12083798") Annotation( "PMID:16624291") Annotation( "Wikipedia:Bleb_(cell_biology)") "The assembly of a bleb, a cell extension caused by localized decoupling of the cytoskeleton from the plasma membrane and characterized by rapid formation, rounded shape, and scarcity of organelles within the protrusion. Plasma membrane blebbing occurs during apoptosis and other cellular processes, including cell locomotion, cell division, and as a result of physical or chemical stresses.") -AnnotationAssertion(Annotation( "GOC:pr") "blebbing") -AnnotationAssertion(Annotation( "GOC:pr") "membrane blebbing") -AnnotationAssertion( "cell blebbing") -AnnotationAssertion(Annotation( "GOC:pr") "plasma membrane bleb assembly") -AnnotationAssertion(Annotation( "GOC:pr") "plasma membrane blebbing") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032060") -AnnotationAssertion(rdfs:label "bleb assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (maintenance of protein location in cell cortex) - -AnnotationAssertion(Annotation( "GOC:vw") "A process in which a protein or protein complex is maintained in a specific location in the cell cortex.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "cortical protein anchoring") -AnnotationAssertion( "GO:0032065") -AnnotationAssertion(rdfs:label "maintenance of protein location in cell cortex") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of nuclease activity) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of nuclease activity, the hydrolysis of ester linkages within nucleic acids.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "nuclease regulator activity") -AnnotationAssertion( "GO:0032069") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "regulation of nuclease activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (regulation of deoxyribonuclease activity) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of deoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "DNase regulator") -AnnotationAssertion( "deoxyribonuclease regulator") -AnnotationAssertion( "GO:0032070") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "regulation of deoxyribonuclease activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (negative regulation of nuclease activity) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops or reduces the rate of nuclease activity, the hydrolysis of ester linkages within nucleic acids.") -AnnotationAssertion( "down regulation of nuclease activity") -AnnotationAssertion( "down-regulation of nuclease activity") -AnnotationAssertion( "downregulation of nuclease activity") -AnnotationAssertion( "inhibition of nuclease activity") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "nuclease inhibitor") -AnnotationAssertion( "GO:0032074") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "negative regulation of nuclease activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of nuclease activity) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of nuclease activity, the hydrolysis of ester linkages within nucleic acids.") -AnnotationAssertion( "up regulation of nuclease activity") -AnnotationAssertion( "up-regulation of nuclease activity") -AnnotationAssertion( "upregulation of nuclease activity") -AnnotationAssertion( "activation of nuclease activity") -AnnotationAssertion( "stimulation of nuclease activity") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "nuclease activator") -AnnotationAssertion( "GO:0032075") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "positive regulation of nuclease activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (negative regulation of deoxyribonuclease activity) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops or reduces the rate of deoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid.") -AnnotationAssertion( "down regulation of deoxyribonuclease activity") -AnnotationAssertion( "down-regulation of deoxyribonuclease activity") -AnnotationAssertion( "downregulation of deoxyribonuclease activity") -AnnotationAssertion( "inhibition of deoxyribonuclease activity") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "DNase inhibitor") -AnnotationAssertion( "deoxyribonuclease inhibitor") -AnnotationAssertion( "GO:0032076") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "negative regulation of deoxyribonuclease activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (positive regulation of deoxyribonuclease activity) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of deoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid.") -AnnotationAssertion( "up regulation of deoxyribonuclease activity") -AnnotationAssertion( "up-regulation of deoxyribonuclease activity") -AnnotationAssertion( "upregulation of deoxyribonuclease activity") -AnnotationAssertion( "activation of deoxyribonuclease activity") -AnnotationAssertion( "stimulation of deoxyribonuclease activity") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "DNase activator") -AnnotationAssertion( "deoxyribonuclease activator") -AnnotationAssertion( "GO:0032077") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "positive regulation of deoxyribonuclease activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (negative regulation of protein binding) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of protein binding.") -AnnotationAssertion( "down regulation of protein binding") -AnnotationAssertion( "down-regulation of protein binding") -AnnotationAssertion( "downregulation of protein binding") -AnnotationAssertion( "inhibition of protein binding") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032091") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "negative regulation of protein binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of protein binding) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of protein binding.") -AnnotationAssertion( "up regulation of protein binding") -AnnotationAssertion( "up-regulation of protein binding") -AnnotationAssertion( "upregulation of protein binding") -AnnotationAssertion( "activation of protein binding") -AnnotationAssertion( "stimulation of protein binding") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032092") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "positive regulation of protein binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of response to external stimulus) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of a response to an external stimulus.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032101") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.") -AnnotationAssertion(rdfs:label "regulation of response to external stimulus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (negative regulation of response to external stimulus) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of a response to an external stimulus.") -AnnotationAssertion( "down regulation of response to external stimulus") -AnnotationAssertion( "down-regulation of response to external stimulus") -AnnotationAssertion( "downregulation of response to external stimulus") -AnnotationAssertion( "inhibition of response to external stimulus") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032102") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.") -AnnotationAssertion(rdfs:label "negative regulation of response to external stimulus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of response to external stimulus) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates, maintains or increases the rate of a response to an external stimulus.") -AnnotationAssertion( "up regulation of response to external stimulus") -AnnotationAssertion( "up-regulation of response to external stimulus") -AnnotationAssertion( "upregulation of response to external stimulus") -AnnotationAssertion( "activation of response to external stimulus") -AnnotationAssertion( "stimulation of response to external stimulus") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032103") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.") -AnnotationAssertion(rdfs:label "positive regulation of response to external stimulus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (dense core granule membrane) - -AnnotationAssertion(Annotation( "GOC:mah") "The lipid bilayer surrounding a dense core granule.") -AnnotationAssertion(Annotation( "GOC:kmv") "dense core vesicle membrane") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0032127") -AnnotationAssertion(rdfs:label "dense core granule membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (regulation of synaptic transmission, cholinergic) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032222") -AnnotationAssertion(rdfs:label "regulation of synaptic transmission, cholinergic") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of synaptic transmission, cholinergic) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine.") -AnnotationAssertion( "down regulation of synaptic transmission, cholinergic") -AnnotationAssertion( "down-regulation of synaptic transmission, cholinergic") -AnnotationAssertion( "downregulation of synaptic transmission, cholinergic") -AnnotationAssertion( "inhibition of synaptic transmission, cholinergic") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032223") -AnnotationAssertion(rdfs:label "negative regulation of synaptic transmission, cholinergic") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of synaptic transmission, cholinergic) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates, maintains or increases the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine.") -AnnotationAssertion( "up regulation of synaptic transmission, cholinergic") -AnnotationAssertion( "up-regulation of synaptic transmission, cholinergic") -AnnotationAssertion( "upregulation of synaptic transmission, cholinergic") -AnnotationAssertion( "activation of synaptic transmission, cholinergic") -AnnotationAssertion( "stimulation of synaptic transmission, cholinergic") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032224") -AnnotationAssertion(rdfs:label "positive regulation of synaptic transmission, cholinergic") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of synaptic transmission, dopaminergic) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of dopaminergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter dopamine.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032225") -AnnotationAssertion(rdfs:label "regulation of synaptic transmission, dopaminergic") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of synaptic transmission, dopaminergic) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates, maintains or increases the frequency, rate or extent of dopaminergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter dopamine.") -AnnotationAssertion( "up regulation of synaptic transmission, dopaminergic") -AnnotationAssertion( "up-regulation of synaptic transmission, dopaminergic") -AnnotationAssertion( "upregulation of synaptic transmission, dopaminergic") -AnnotationAssertion( "activation of synaptic transmission, dopaminergic") -AnnotationAssertion( "stimulation of synaptic transmission, dopaminergic") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032226") -AnnotationAssertion(rdfs:label "positive regulation of synaptic transmission, dopaminergic") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of synaptic transmission, dopaminergic) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of dopaminergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter dopamine.") -AnnotationAssertion( "down regulation of synaptic transmission, dopaminergic") -AnnotationAssertion( "down-regulation of synaptic transmission, dopaminergic") -AnnotationAssertion( "downregulation of synaptic transmission, dopaminergic") -AnnotationAssertion( "inhibition of synaptic transmission, dopaminergic") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032227") -AnnotationAssertion(rdfs:label "negative regulation of synaptic transmission, dopaminergic") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of synaptic transmission, GABAergic) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA).") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032228") -AnnotationAssertion(rdfs:label "regulation of synaptic transmission, GABAergic") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of synaptic transmission, GABAergic) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA).") -AnnotationAssertion( "down regulation of synaptic transmission, GABAergic") -AnnotationAssertion( "down-regulation of synaptic transmission, GABAergic") -AnnotationAssertion( "downregulation of synaptic transmission, GABAergic") -AnnotationAssertion( "inhibition of synaptic transmission, GABAergic") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032229") -AnnotationAssertion(rdfs:label "negative regulation of synaptic transmission, GABAergic") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of synaptic transmission, GABAergic) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates, maintains or increases the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA).") -AnnotationAssertion( "up regulation of synaptic transmission, GABAergic") -AnnotationAssertion( "up-regulation of synaptic transmission, GABAergic") -AnnotationAssertion( "upregulation of synaptic transmission, GABAergic") -AnnotationAssertion( "activation of synaptic transmission, GABAergic") -AnnotationAssertion( "stimulation of synaptic transmission, GABAergic") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032230") -AnnotationAssertion(rdfs:label "positive regulation of synaptic transmission, GABAergic") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of actin filament bundle assembly) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the assembly of actin filament bundles.") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "regulation of actin cable assembly") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") "regulation of actin filament bundle formation") -AnnotationAssertion( "GO:0032231") -AnnotationAssertion(rdfs:label "regulation of actin filament bundle assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (negative regulation of actin filament bundle assembly) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly of actin filament bundles.") -AnnotationAssertion( "down regulation of actin filament bundle formation") -AnnotationAssertion( "down-regulation of actin filament bundle formation") -AnnotationAssertion( "downregulation of actin filament bundle formation") -AnnotationAssertion( "inhibition of actin filament bundle formation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032232") -AnnotationAssertion(rdfs:label "negative regulation of actin filament bundle assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (positive regulation of actin filament bundle assembly) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of the assembly of actin filament bundles.") -AnnotationAssertion( "up regulation of actin filament bundle formation") -AnnotationAssertion( "up-regulation of actin filament bundle formation") -AnnotationAssertion( "upregulation of actin filament bundle formation") -AnnotationAssertion( "activation of actin filament bundle formation") -AnnotationAssertion( "stimulation of actin filament bundle formation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032233") -AnnotationAssertion(rdfs:label "positive regulation of actin filament bundle assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (adenosine transport) - -AnnotationAssertion(Annotation( "GOC:mah") "The directed movement of adenosine, adenine riboside, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032238") -AnnotationAssertion(rdfs:label "adenosine transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of nucleobase-containing compound transport) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport") -AnnotationAssertion( "GO:0032239") -AnnotationAssertion(rdfs:label "regulation of nucleobase-containing compound transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of nucleobase-containing compound transport) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion( "down regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport") -AnnotationAssertion( "down-regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport") -AnnotationAssertion( "downregulation of nucleobase, nucleoside, nucleotide and nucleic acid transport") -AnnotationAssertion( "inhibition of nucleobase, nucleoside, nucleotide and nucleic acid transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport") -AnnotationAssertion( "GO:0032240") -AnnotationAssertion(rdfs:label "negative regulation of nucleobase-containing compound transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of nucleobase-containing compound transport) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion( "up regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport") -AnnotationAssertion( "up-regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport") -AnnotationAssertion( "upregulation of nucleobase, nucleoside, nucleotide and nucleic acid transport") -AnnotationAssertion( "activation of nucleobase, nucleoside, nucleotide and nucleic acid transport") -AnnotationAssertion( "stimulation of nucleobase, nucleoside, nucleotide and nucleic acid transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport") -AnnotationAssertion( "GO:0032241") -AnnotationAssertion(rdfs:label "positive regulation of nucleobase-containing compound transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of nucleoside transport) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the directed movement of a nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032242") -AnnotationAssertion(rdfs:label "regulation of nucleoside transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of nucleoside transport) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion( "down regulation of nucleoside transport") -AnnotationAssertion( "down-regulation of nucleoside transport") -AnnotationAssertion( "downregulation of nucleoside transport") -AnnotationAssertion( "inhibition of nucleoside transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032243") -AnnotationAssertion(rdfs:label "negative regulation of nucleoside transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of nucleoside transport) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of the directed movement of a nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion( "up regulation of nucleoside transport") -AnnotationAssertion( "up-regulation of nucleoside transport") -AnnotationAssertion( "upregulation of nucleoside transport") -AnnotationAssertion( "activation of nucleoside transport") -AnnotationAssertion( "stimulation of nucleoside transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032244") -AnnotationAssertion(rdfs:label "positive regulation of nucleoside transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of purine nucleoside transport) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the directed movement of a purine nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032245") -AnnotationAssertion(rdfs:label "regulation of purine nucleoside transport") -SubClassOf( ) - -# Class: (negative regulation of purine nucleoside transport) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a purine nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion( "down regulation of purine nucleoside transport") -AnnotationAssertion( "down-regulation of purine nucleoside transport") -AnnotationAssertion( "downregulation of purine nucleoside transport") -AnnotationAssertion( "inhibition of purine nucleoside transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032247") -AnnotationAssertion(rdfs:label "negative regulation of purine nucleoside transport") -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of purine nucleoside transport) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of the directed movement of a purine nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion( "up regulation of purine nucleoside transport") -AnnotationAssertion( "up-regulation of purine nucleoside transport") -AnnotationAssertion( "upregulation of purine nucleoside transport") -AnnotationAssertion( "activation of purine nucleoside transport") -AnnotationAssertion( "stimulation of purine nucleoside transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032248") -AnnotationAssertion(rdfs:label "positive regulation of purine nucleoside transport") -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of adenosine transport) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the directed movement of adenosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032249") -AnnotationAssertion(rdfs:label "regulation of adenosine transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (negative regulation of adenosine transport) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of adenosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion( "down regulation of adenosine transport") -AnnotationAssertion( "down-regulation of adenosine transport") -AnnotationAssertion( "downregulation of adenosine transport") -AnnotationAssertion( "inhibition of adenosine transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032250") -AnnotationAssertion(rdfs:label "negative regulation of adenosine transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (positive regulation of adenosine transport) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of the directed movement of adenosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion( "up regulation of adenosine transport") -AnnotationAssertion( "up-regulation of adenosine transport") -AnnotationAssertion( "upregulation of adenosine transport") -AnnotationAssertion( "activation of adenosine transport") -AnnotationAssertion( "stimulation of adenosine transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032251") -AnnotationAssertion(rdfs:label "positive regulation of adenosine transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (secretory granule localization) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process in which a secretory granule is transported to, and/or maintained in, a specific location within the cell.") -AnnotationAssertion(Annotation( "GOC:mah") "secretory granule localisation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "secretory granule clustering") -AnnotationAssertion( "GO:0032252") -AnnotationAssertion(rdfs:label "secretory granule localization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (dense core granule localization) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process in which a dense core granule is transported to, and/or maintained in, a specific location within the cell.") -AnnotationAssertion(Annotation( "GOC:mah") "dense core granule localisation") -AnnotationAssertion(Annotation( "GOC:kmv") "dense core vesicle localization") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "dense core granule clustering") -AnnotationAssertion( "GO:0032253") -AnnotationAssertion(rdfs:label "dense core granule localization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of protein polymerization) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the process of creating protein polymers.") -AnnotationAssertion( "regulation of protein polymerisation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032271") -AnnotationAssertion(rdfs:label "regulation of protein polymerization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of protein polymerization) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of the process of creating protein polymers.") -AnnotationAssertion( "down regulation of protein polymerization") -AnnotationAssertion( "down-regulation of protein polymerization") -AnnotationAssertion( "downregulation of protein polymerization") -AnnotationAssertion( "inhibition of protein polymerization") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032272") -AnnotationAssertion(rdfs:label "negative regulation of protein polymerization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of protein polymerization) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of the process of creating protein polymers.") -AnnotationAssertion( "up regulation of protein polymerization") -AnnotationAssertion( "up-regulation of protein polymerization") -AnnotationAssertion( "upregulation of protein polymerization") -AnnotationAssertion( "activation of protein polymerization") -AnnotationAssertion( "stimulation of protein polymerization") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032273") -AnnotationAssertion(rdfs:label "positive regulation of protein polymerization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (gonadotropin secretion) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "ISBN:0721662544") "The regulated release of a gonadotropin, any hormone that stimulates the gonads, especially follicle-stimulating hormone and luteinizing hormone.") -AnnotationAssertion( "gonadotrophin secretion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032274") -AnnotationAssertion(rdfs:label "gonadotropin secretion") -SubClassOf( ) - -# Class: (luteinizing hormone secretion) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "The regulated release of luteinizing hormone, a gonadotropic glycoprotein hormone secreted by the anterior pituitary.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032275") -AnnotationAssertion(rdfs:label "luteinizing hormone secretion") -SubClassOf( ) - -# Class: (regulation of gonadotropin secretion) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the regulated release of a gonadotropin.") -AnnotationAssertion( "regulation of gonadotrophin secretion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032276") -AnnotationAssertion(rdfs:label "regulation of gonadotropin secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (negative regulation of gonadotropin secretion) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a gonadotropin.") -AnnotationAssertion( "down regulation of gonadotropin secretion") -AnnotationAssertion( "down-regulation of gonadotropin secretion") -AnnotationAssertion( "downregulation of gonadotropin secretion") -AnnotationAssertion(Annotation( "GOC:dph") "negative regulation of gonadotrophin secretion") -AnnotationAssertion( "inhibition of gonadotropin secretion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032277") -AnnotationAssertion(rdfs:label "negative regulation of gonadotropin secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of gonadotropin secretion) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of the regulated release of a gonadotropin.") -AnnotationAssertion(Annotation( "GOC:dph") "positive regulation of gonadotrophin secretion") -AnnotationAssertion( "up regulation of gonadotropin secretion") -AnnotationAssertion( "up-regulation of gonadotropin secretion") -AnnotationAssertion( "upregulation of gonadotropin secretion") -AnnotationAssertion( "activation of gonadotropin secretion") -AnnotationAssertion( "stimulation of gonadotropin secretion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032278") -AnnotationAssertion(rdfs:label "positive regulation of gonadotropin secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (myelin assembly) - -AnnotationAssertion(Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:tb") "The process in which the wraps of cell membrane that constitute myelin are laid down around an axon in the central or peripheral nervous system.") -AnnotationAssertion( "myelin sheath assembly") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "myelin formation") -AnnotationAssertion( "GO:0032288") -AnnotationAssertion(rdfs:label "myelin assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (central nervous system myelin formation) - -AnnotationAssertion(Annotation( "GOC:dgh") "The process in which the wraps of cell membrane that constitute myelin are laid down around an axon by an oligodendrocyte in the central nervous system.") -AnnotationAssertion( "central nervous system myelin sheath formation") -AnnotationAssertion( "myelin formation in central nervous system") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032289") -AnnotationAssertion(rdfs:label "central nervous system myelin formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - -# Class: (peripheral nervous system myelin formation) - -AnnotationAssertion(Annotation( "GOC:dgh") "The process in which the wraps of cell membrane that constitute myelin are laid down around an axon by Schwann cells in the peripheral nervous system.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/19106"^^xsd:anyURI) -AnnotationAssertion( "myelin formation in peripheral nervous system") -AnnotationAssertion( "peripheral nervous system myelin sheath formation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032290") -AnnotationAssertion(rdfs:label "peripheral nervous system myelin formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (axon ensheathment in central nervous system) - -AnnotationAssertion(Annotation( "GOC:dgh") "The process in which a glial cell membrane closes around an axon in the central nervous system. This can be a myelinating or a non-myelinating neuron-glial interaction.") -AnnotationAssertion( "ensheathment of axons in central nervous system") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032291") -AnnotationAssertion(rdfs:label "axon ensheathment in central nervous system") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - -# Class: (peripheral nervous system axon ensheathment) - -AnnotationAssertion(Annotation( "GOC:dgh") "The process in which a Schwann cell membrane closes around an axon in the peripheral nervous system. This can be a myelinating or a non-myelinating neuron-glial interaction.") -AnnotationAssertion( "ensheathment of axons in peripheral nervous system") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032292") -AnnotationAssertion(rdfs:label "peripheral nervous system axon ensheathment") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of chondrocyte differentiation) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of chondrocyte differentiation.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032330") -AnnotationAssertion(rdfs:label "regulation of chondrocyte differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of chondrocyte differentiation) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of chondrocyte differentiation.") -AnnotationAssertion( "down regulation of chondrocyte differentiation") -AnnotationAssertion( "down-regulation of chondrocyte differentiation") -AnnotationAssertion( "downregulation of chondrocyte differentiation") -AnnotationAssertion( "inhibition of chondrocyte differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032331") -AnnotationAssertion(rdfs:label "negative regulation of chondrocyte differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of chondrocyte differentiation) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of chondrocyte differentiation.") -AnnotationAssertion( "up regulation of chondrocyte differentiation") -AnnotationAssertion( "up-regulation of chondrocyte differentiation") -AnnotationAssertion( "upregulation of chondrocyte differentiation") -AnnotationAssertion( "activation of chondrocyte differentiation") -AnnotationAssertion( "stimulation of chondrocyte differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032332") -AnnotationAssertion(rdfs:label "positive regulation of chondrocyte differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - # Class: (aldosterone metabolic process) AnnotationAssertion(Annotation( "PMID:16527843") "The chemical reactions and pathways involving aldosterone, a corticosteroid hormone that is produced by the zona glomerulosa of the adrenal cortex and regulates salt (sodium and potassium) and water balance.") @@ -74018,7 +24101,6 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0032341") AnnotationAssertion(rdfs:label "aldosterone metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ) @@ -74031,7 +24113,6 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:0032342") AnnotationAssertion(rdfs:label "aldosterone biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ) @@ -74039,403 +24120,6 @@ SubClassOf( ) SubClassOf( ) -# Class: (aldosterone catabolic process) - -AnnotationAssertion(Annotation( "PMID:16527843") "The chemical reactions and pathways resulting in the breakdown of aldosterone, a corticosteroid hormone that is produced by the zona glomerulosa of the adrenal cortex and regulates salt (sodium and potassium) and water balance.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032343") -AnnotationAssertion(rdfs:label "aldosterone catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of aldosterone metabolic process) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving aldosterone.") -AnnotationAssertion( "regulation of aldosterone metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032344") -AnnotationAssertion(rdfs:label "regulation of aldosterone metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of aldosterone metabolic process) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving aldosterone.") -AnnotationAssertion( "down regulation of aldosterone metabolic process") -AnnotationAssertion( "down-regulation of aldosterone metabolic process") -AnnotationAssertion( "downregulation of aldosterone metabolic process") -AnnotationAssertion( "negative regulation of aldosterone metabolism") -AnnotationAssertion( "inhibition of aldosterone metabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032345") -AnnotationAssertion(rdfs:label "negative regulation of aldosterone metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of aldosterone metabolic process) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving aldosterone.") -AnnotationAssertion( "positive regulation of aldosterone metabolism") -AnnotationAssertion( "up regulation of aldosterone metabolic process") -AnnotationAssertion( "up-regulation of aldosterone metabolic process") -AnnotationAssertion( "upregulation of aldosterone metabolic process") -AnnotationAssertion( "activation of aldosterone metabolic process") -AnnotationAssertion( "stimulation of aldosterone metabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032346") -AnnotationAssertion(rdfs:label "positive regulation of aldosterone metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of aldosterone biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of aldosterone.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032347") -AnnotationAssertion(rdfs:label "regulation of aldosterone biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of aldosterone biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of aldosterone.") -AnnotationAssertion( "down regulation of aldosterone biosynthetic process") -AnnotationAssertion( "down-regulation of aldosterone biosynthetic process") -AnnotationAssertion( "downregulation of aldosterone biosynthetic process") -AnnotationAssertion( "inhibition of aldosterone biosynthetic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032348") -AnnotationAssertion(rdfs:label "negative regulation of aldosterone biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of aldosterone biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of aldosterone.") -AnnotationAssertion( "up regulation of aldosterone biosynthetic process") -AnnotationAssertion( "up-regulation of aldosterone biosynthetic process") -AnnotationAssertion( "upregulation of aldosterone biosynthetic process") -AnnotationAssertion( "activation of aldosterone biosynthetic process") -AnnotationAssertion( "stimulation of aldosterone biosynthetic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032349") -AnnotationAssertion(rdfs:label "positive regulation of aldosterone biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of hormone metabolic process) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving any hormone.") -AnnotationAssertion( "regulation of hormone metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032350") -AnnotationAssertion(rdfs:label "regulation of hormone metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of hormone metabolic process) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving any hormone.") -AnnotationAssertion( "down regulation of hormone metabolic process") -AnnotationAssertion( "down-regulation of hormone metabolic process") -AnnotationAssertion( "downregulation of hormone metabolic process") -AnnotationAssertion( "negative regulation of hormone metabolism") -AnnotationAssertion( "inhibition of hormone metabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032351") -AnnotationAssertion(rdfs:label "negative regulation of hormone metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of hormone metabolic process) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving any hormone.") -AnnotationAssertion( "positive regulation of hormone metabolism") -AnnotationAssertion( "up regulation of hormone metabolic process") -AnnotationAssertion( "up-regulation of hormone metabolic process") -AnnotationAssertion( "upregulation of hormone metabolic process") -AnnotationAssertion( "activation of hormone metabolic process") -AnnotationAssertion( "stimulation of hormone metabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032352") -AnnotationAssertion(rdfs:label "positive regulation of hormone metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of hormone biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hormones.") -AnnotationAssertion( "down regulation of hormone biosynthetic process") -AnnotationAssertion( "down-regulation of hormone biosynthetic process") -AnnotationAssertion( "downregulation of hormone biosynthetic process") -AnnotationAssertion( "inhibition of hormone biosynthetic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032353") -AnnotationAssertion(rdfs:label "negative regulation of hormone biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (intracellular oxygen homeostasis) - -AnnotationAssertion(Annotation( "GOC:rph") "A homeostatic process involved in the maintenance of a steady state level of oxygen within a cell.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/24224"^^xsd:anyURI) -AnnotationAssertion( "oxygen homeostasis") -AnnotationAssertion( "cellular oxygen homeostasis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032364") -AnnotationAssertion(rdfs:label "intracellular oxygen homeostasis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (intracellular lipid transport) - -AnnotationAssertion(Annotation( "GOC:mah") "The directed movement of lipids within cells.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032365") -AnnotationAssertion(rdfs:label "intracellular lipid transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (regulation of lipid transport) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032368") -AnnotationAssertion(rdfs:label "regulation of lipid transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (negative regulation of lipid transport) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion( "down regulation of lipid transport") -AnnotationAssertion( "down-regulation of lipid transport") -AnnotationAssertion( "downregulation of lipid transport") -AnnotationAssertion( "inhibition of lipid transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032369") -AnnotationAssertion(rdfs:label "negative regulation of lipid transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of lipid transport) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion( "up regulation of lipid transport") -AnnotationAssertion( "up-regulation of lipid transport") -AnnotationAssertion( "upregulation of lipid transport") -AnnotationAssertion( "activation of lipid transport") -AnnotationAssertion( "stimulation of lipid transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032370") -AnnotationAssertion(rdfs:label "positive regulation of lipid transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (regulation of intracellular lipid transport) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the directed movement of lipids within cells.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032377") -AnnotationAssertion(rdfs:label "regulation of intracellular lipid transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of intracellular lipid transport) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of lipids within cells.") -AnnotationAssertion( "down regulation of intracellular lipid transport") -AnnotationAssertion( "down-regulation of intracellular lipid transport") -AnnotationAssertion( "downregulation of intracellular lipid transport") -AnnotationAssertion( "inhibition of intracellular lipid transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032378") -AnnotationAssertion(rdfs:label "negative regulation of intracellular lipid transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of intracellular lipid transport) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of the directed movement of lipids within cells.") -AnnotationAssertion( "up regulation of intracellular lipid transport") -AnnotationAssertion( "up-regulation of intracellular lipid transport") -AnnotationAssertion( "upregulation of intracellular lipid transport") -AnnotationAssertion( "activation of intracellular lipid transport") -AnnotationAssertion( "stimulation of intracellular lipid transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032379") -AnnotationAssertion(rdfs:label "positive regulation of intracellular lipid transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of intracellular transport) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the directed movement of substances within cells.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032386") -AnnotationAssertion(rdfs:label "regulation of intracellular transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of intracellular transport) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances within cells.") -AnnotationAssertion( "down regulation of intracellular transport") -AnnotationAssertion( "down-regulation of intracellular transport") -AnnotationAssertion( "downregulation of intracellular transport") -AnnotationAssertion( "inhibition of intracellular transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032387") -AnnotationAssertion(rdfs:label "negative regulation of intracellular transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of intracellular transport) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of the directed movement of substances within cells.") -AnnotationAssertion( "up regulation of intracellular transport") -AnnotationAssertion( "up-regulation of intracellular transport") -AnnotationAssertion( "upregulation of intracellular transport") -AnnotationAssertion( "activation of intracellular transport") -AnnotationAssertion( "stimulation of intracellular transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032388") -AnnotationAssertion(rdfs:label "positive regulation of intracellular transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (melanosome localization) - -AnnotationAssertion(Annotation( "GOC:ln") "Any process in which a melanosome is transported to, and/or maintained in, a specific location within the cell.") -AnnotationAssertion(Annotation( "GOC:mah") "melanosome localisation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032400") -AnnotationAssertion(rdfs:label "melanosome localization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (establishment of melanosome localization) - -AnnotationAssertion(Annotation( "GOC:mah") "The directed movement of a melanosome to a specific location.") -AnnotationAssertion(Annotation( "GOC:mah") "establishment of melanosome localisation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032401") -AnnotationAssertion(rdfs:label "establishment of melanosome localization") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (melanosome transport) - -AnnotationAssertion(Annotation( "GOC:ln") "The directed movement of melanosomes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032402") -AnnotationAssertion(rdfs:label "melanosome transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of transporter activity) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the activity of a transporter.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032409") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "regulation of transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of transporter activity) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops or reduces the activity of a transporter.") -AnnotationAssertion( "down regulation of transporter activity") -AnnotationAssertion( "down-regulation of transporter activity") -AnnotationAssertion( "downregulation of transporter activity") -AnnotationAssertion( "inhibition of transporter activity") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032410") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "negative regulation of transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (positive regulation of transporter activity) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the activity of a transporter.") -AnnotationAssertion( "up regulation of transporter activity") -AnnotationAssertion( "up-regulation of transporter activity") -AnnotationAssertion( "upregulation of transporter activity") -AnnotationAssertion( "activation of transporter activity") -AnnotationAssertion( "stimulation of transporter activity") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032411") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "positive regulation of transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of monoatomic ion transmembrane transporter activity) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:tb") "Any process that modulates the activity of an ion transporter.") -AnnotationAssertion( "regulation of ion transmembrane transporter activity") -AnnotationAssertion(Annotation( "GOC:tb") "regulation of ion transporter activity") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032412") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "regulation of monoatomic ion transmembrane transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of ion transmembrane transporter activity) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:tb") "Any process that stops or reduces the activity of an ion transporter.") -AnnotationAssertion( "down regulation of ion transporter activity") -AnnotationAssertion( "down-regulation of ion transporter activity") -AnnotationAssertion( "downregulation of ion transporter activity") -AnnotationAssertion(Annotation( "GOC:tb") "negative regulation of ion transporter activity") -AnnotationAssertion( "inhibition of ion transporter activity") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032413") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "negative regulation of ion transmembrane transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of ion transmembrane transporter activity) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:tb") "Any process that activates or increases the activity of an ion transporter.") -AnnotationAssertion(Annotation( "GOC:tb") "positive regulation of ion transporter activity") -AnnotationAssertion( "up regulation of ion transporter activity") -AnnotationAssertion( "up-regulation of ion transporter activity") -AnnotationAssertion( "upregulation of ion transporter activity") -AnnotationAssertion( "activation of ion transporter activity") -AnnotationAssertion( "stimulation of ion transporter activity") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032414") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "positive regulation of ion transmembrane transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (lysosome localization) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process in which a lysosome is transported to, and/or maintained in, a specific location.") -AnnotationAssertion(Annotation( "GOC:mah") "lysosome localisation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032418") -AnnotationAssertion(rdfs:label "lysosome localization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (actin filament bundle) AnnotationAssertion(Annotation( "GOC:mah") "An assembly of actin filaments that are on the same axis but may be oriented with the same or opposite polarities and may be packed with different levels of tightness.") @@ -74450,63 +24134,6 @@ SubClassOf( ObjectSomeValuesFrom( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (melanosome organization) - -AnnotationAssertion(Annotation( "GOC:vk") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a melanosome. A melanosome is a tissue-specific, membrane-bounded cytoplasmic organelle within which melanin pigments are synthesized and stored.") -AnnotationAssertion(Annotation( "GOC:mah") "melanosome organisation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:mah") "melanosome organization and biogenesis") -AnnotationAssertion( "GO:0032438") -AnnotationAssertion(rdfs:label "melanosome organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (Golgi calcium ion homeostasis) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process involved in the maintenance of an internal steady state of calcium ions within the Golgi apparatus of a cell or between the Golgi and its surroundings.") -AnnotationAssertion( "Golgi calcium ion concentration regulation") -AnnotationAssertion( "calcium ion homeostasis in Golgi") -AnnotationAssertion( "regulation of Golgi calcium ion concentration") -AnnotationAssertion( "regulation of calcium ion concentration in Golgi") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032468") -AnnotationAssertion(rdfs:label "Golgi calcium ion homeostasis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - -# Class: (Golgi calcium ion transport) - -AnnotationAssertion(Annotation( "GOC:mah") "The directed movement of calcium ions (Ca2+) into, out of or within the Golgi apparatus.") -AnnotationAssertion( "Golgi calcium transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032472") -AnnotationAssertion(rdfs:label "Golgi calcium ion transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (otolith morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dgh") "The process in which the anatomical structures of an otolith are generated and organized.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032474") -AnnotationAssertion(rdfs:label "otolith morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (otolith formation) - -AnnotationAssertion(Annotation( "GOC:dgh") "The process that gives rise to an otolith. This process pertains to the initial formation of a structure from unspecified parts.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032475") -AnnotationAssertion(rdfs:label "otolith formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (multicellular organismal process) AnnotationAssertion(Annotation( "GOC:curators") Annotation( "GOC:dph") Annotation( "GOC:isa_complete") Annotation( "GOC:tb") "Any biological process, occurring at the level of a multicellular organism, pertinent to its function.") @@ -74567,181 +24194,12 @@ AnnotationAssertion(rdfs:label "mult SubClassOf( ) SubClassOf( ) -# Class: (maintenance of protein location in cell) - -AnnotationAssertion(Annotation( "GOC:isa_complete") Annotation( "GOC:mah") "Any process in which a protein is maintained in a specific location within, or in the membrane of, a cell, and is prevented from moving elsewhere.") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "maintenance of protein localization in cell") -AnnotationAssertion( "GO:0032507") -AnnotationAssertion(rdfs:label "maintenance of protein location in cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - -# Class: (microvillus organization) - -AnnotationAssertion(Annotation( "GOC:mah") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a microvillus, a thin cylindrical membrane-covered projection on the surface of a cell.") -AnnotationAssertion( ) -AnnotationAssertion(Annotation( "GOC:mah") "microvillus organisation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:mah") "microvillus organization and biogenesis") -AnnotationAssertion( "GO:0032528") -AnnotationAssertion(rdfs:label "microvillus organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) -DisjointClasses( ObjectSomeValuesFrom( )) - -# Class: (follicle cell microvillus organization) - -AnnotationAssertion(Annotation( "GOC:sart") Annotation( "PMID:16507588") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a microvillus on a follicle cell. A microvillus is a thin cylindrical membrane-covered projection on the surface of an animal cell containing a core bundle of actin filaments.") -AnnotationAssertion(Annotation( "GOC:mah") "follicle cell microvillus organisation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:mah") "follicle cell microvillus organization and biogenesis") -AnnotationAssertion( "GO:0032529") -AnnotationAssertion(rdfs:label "follicle cell microvillus organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of microvillus organization) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a microvillus.") -AnnotationAssertion(Annotation( "GOC:mah") "regulation of microvillus organisation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:mah") "regulation of microvillus organization and biogenesis") -AnnotationAssertion( "GO:0032530") -AnnotationAssertion(rdfs:label "regulation of microvillus organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of follicle cell microvillus organization) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a microvillus on a follicle cell.") -AnnotationAssertion(Annotation( "GOC:mah") "regulation of follicle cell microvillus organisation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:mah") "regulation of follicle cell microvillus organization and biogenesis") -AnnotationAssertion( "GO:0032531") -AnnotationAssertion(rdfs:label "regulation of follicle cell microvillus organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of microvillus assembly) - -AnnotationAssertion(Annotation( "GOC:mah") "A process that modulates the formation of a microvillus.") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:mah") "regulation of microvillus biogenesis") -AnnotationAssertion( "GO:0032534") -AnnotationAssertion(rdfs:label "regulation of microvillus assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (ribonucleoside binding) - -AnnotationAssertion(Annotation( "GOC:mah") "Binding to a ribonucleoside, a compound consisting of a purine or pyrimidine nitrogenous base linked to ribose.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0032549") -AnnotationAssertion(rdfs:label "ribonucleoside binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (purine ribonucleoside binding) - -AnnotationAssertion(Annotation( "GOC:mah") "Binding to a purine ribonucleoside, a compound consisting of a purine base linked to ribose.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0032550") -AnnotationAssertion(rdfs:label "purine ribonucleoside binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (ribonucleotide binding) - -AnnotationAssertion(Annotation( "GOC:mah") "Binding to a ribonucleotide, any compound consisting of a ribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0032553") -AnnotationAssertion(rdfs:label "ribonucleotide binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (purine ribonucleotide binding) - -AnnotationAssertion(Annotation( "GOC:mah") "Binding to a purine ribonucleotide, any compound consisting of a purine ribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0032555") -AnnotationAssertion(rdfs:label "purine ribonucleotide binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (adenyl ribonucleotide binding) - -AnnotationAssertion(Annotation( "GOC:mah") "Binding to an adenyl ribonucleotide, any compound consisting of adenosine esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0032559") -AnnotationAssertion(rdfs:label "adenyl ribonucleotide binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (response to progesterone) - -AnnotationAssertion(Annotation( "GOC:sl") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a progesterone stimulus.") -AnnotationAssertion(Annotation( "GOC:dos") "response to progesterone stimulus") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032570") -AnnotationAssertion(rdfs:label "response to progesterone") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (neuron projection membrane) - -AnnotationAssertion(Annotation( "GOC:mah") "The portion of the plasma membrane surrounding a neuron projection.") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0032589") -AnnotationAssertion(rdfs:label "neuron projection membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (dendrite membrane) - -AnnotationAssertion(Annotation( "GOC:mah") "The portion of the plasma membrane surrounding a dendrite.") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0032590") -AnnotationAssertion(rdfs:label "dendrite membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (protein transport within lipid bilayer) - -AnnotationAssertion(Annotation( "GOC:mah") "The directed movement of a protein from one location to another within a lipid bilayer.") -AnnotationAssertion( "protein translocation within membrane") -AnnotationAssertion( "receptor translocation within membrane") -AnnotationAssertion( "receptor transport within lipid bilayer") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032594") -AnnotationAssertion(rdfs:label "protein transport within lipid bilayer") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (RNA biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:txnOH") "The chemical reactions and pathways resulting in the formation of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. Includes polymerization of ribonucleotide monomers. Refers not only to transcription but also to e.g. viral RNA replication.") -AnnotationAssertion( "GO:0062103") -AnnotationAssertion( "RNA anabolism") -AnnotationAssertion( "RNA biosynthesis") -AnnotationAssertion( "RNA formation") -AnnotationAssertion( "RNA synthesis") -AnnotationAssertion( "double-stranded RNA biosynthesis") -AnnotationAssertion( "double-stranded RNA biosynthetic process") -AnnotationAssertion( "dsRNA biosynthesis") -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_telomere") Annotation( "GOC:nc") Annotation( "GOC:rl") "dsRNA biosynthetic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032774") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "Note that, in some cases, viral RNA replication and viral transcription from RNA actually refer to the same process, but may be called differently depending on the focus of a specific research study.") -AnnotationAssertion(rdfs:label "RNA biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (bile acid secretion) AnnotationAssertion(Annotation( "GOC:ecd") "The regulated release of bile acid, composed of any of a group of steroid carboxylic acids occurring in bile, by a cell or a tissue.") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0032782") AnnotationAssertion(rdfs:label "bile acid secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) # Class: (monocarboxylic acid metabolic process) @@ -74753,152 +24211,8 @@ AnnotationAssertion( "GO:0032787") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "monocarboxylic acid metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (ribosome disassembly) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:vk") "The disaggregation of a ribosome into its constituent components; includes the dissociation of ribosomal subunits.") -AnnotationAssertion(Annotation( "GOC:db") Annotation( "PMID:9463391") "ribosome recycling") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "ribosome dissociation factor") -AnnotationAssertion( "GO:0032790") -AnnotationAssertion(rdfs:label "ribosome disassembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (lacrimal gland development) - -AnnotationAssertion(Annotation( "GOC:ln") "The process whose specific outcome is the progression of the lacrimal gland over time, from its formation to the mature structure. The lacrimal gland produces secretions that lubricate and protect the cornea of the eye.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032808") -AnnotationAssertion(rdfs:label "lacrimal gland development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (negative regulation of epinephrine secretion) - -AnnotationAssertion(Annotation( "GOC:vk") "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of epinephrine.") -AnnotationAssertion( "down regulation of epinephrine secretion") -AnnotationAssertion( "down-regulation of epinephrine secretion") -AnnotationAssertion( "downregulation of epinephrine secretion") -AnnotationAssertion( "negative regulation of adrenaline secretion") -AnnotationAssertion( "inhibition of epinephrine secretion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032811") -AnnotationAssertion(rdfs:label "negative regulation of epinephrine secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of epinephrine secretion) - -AnnotationAssertion(Annotation( "GOC:vk") "Any process that activates or increases the frequency, rate or extent of the regulated release of epinephrine.") -AnnotationAssertion( "positive regulation of adrenaline secretion") -AnnotationAssertion( "up regulation of epinephrine secretion") -AnnotationAssertion( "up-regulation of epinephrine secretion") -AnnotationAssertion( "upregulation of epinephrine secretion") -AnnotationAssertion( "activation of epinephrine secretion") -AnnotationAssertion( "stimulation of epinephrine secretion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032812") -AnnotationAssertion(rdfs:label "positive regulation of epinephrine secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (glomerulus development) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:mtg_kidney_jan10") "The progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the vertebrate kidney. The glomerulus is part of the nephron and is restricted to one body segment.") -AnnotationAssertion( "glomerular development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032835") -AnnotationAssertion(rdfs:label "glomerulus development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (glomerular basement membrane development) - -AnnotationAssertion(Annotation( "GOC:sr") "The process whose specific outcome is the progression of the glomerular basement membrane over time, from its formation to the mature structure. The glomerular basement membrane is the basal laminal portion of the glomerulus which performs the actual filtration.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032836") -AnnotationAssertion(rdfs:label "glomerular basement membrane development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (plasma membrane bounded cell projection cytoplasm) - -AnnotationAssertion(Annotation( "GOC:krc") Annotation( "GOC:mah") "All of the contents of a plasma membrane bounded cell projection, excluding the plasma membrane surrounding the projection.") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0032838") -AnnotationAssertion(rdfs:label "plasma membrane bounded cell projection cytoplasm") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (dendrite cytoplasm) - -AnnotationAssertion(Annotation( "GOC:mah") "All of the contents of a dendrite, excluding the surrounding plasma membrane.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/14472"^^xsd:anyURI) -AnnotationAssertion( "dendritic cytoplasm") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0032839") -AnnotationAssertion(rdfs:label "dendrite cytoplasm") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (calcitonin binding) - -AnnotationAssertion(Annotation( "GOC:ecd") "Binding to calcitonin, a peptide hormone responsible for reducing serum calcium levels by inhibiting osteoclastic bone reabsorption and promoting renal calcium excretion. It is synthesized and released by the C cells of the thyroid.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0032841") -AnnotationAssertion(rdfs:label "calcitonin binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (response to insulin) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "ISBN:0198506732") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms.") -AnnotationAssertion(Annotation( "GOC:dos") "response to insulin stimulus") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032868") -AnnotationAssertion(rdfs:label "response to insulin") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (cellular response to insulin stimulus) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "ISBN:0198506732") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032869") -AnnotationAssertion(rdfs:label "cellular response to insulin stimulus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (cellular response to hormone stimulus) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hormone stimulus.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032870") -AnnotationAssertion(rdfs:label "cellular response to hormone stimulus") -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of karyogamy) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of karyogamy, the creation of a single nucleus from multiple nuclei as a result of membrane fusion.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032871") -AnnotationAssertion(rdfs:label "regulation of karyogamy") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of establishment or maintenance of cell polarity) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032878") -AnnotationAssertion(rdfs:label "regulation of establishment or maintenance of cell polarity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (regulation of localization) AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of any process in which a cell, a substance, or a cellular entity is transported to, or maintained in, a specific location.") @@ -74906,116 +24220,8 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:0032879") AnnotationAssertion(rdfs:label "regulation of localization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (regulation of protein localization) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mah") Annotation( "GOC:tb") "Any process that modulates the frequency, rate or extent of any process in which a protein is transported to, or maintained in, a specific location.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/22021"^^xsd:anyURI) -AnnotationAssertion( "jl") -AnnotationAssertion( "2015-01-20T14:32:14Z") -AnnotationAssertion( "GO:1903827") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of cellular protein localisation") -AnnotationAssertion( "regulation of cellular protein localization") -AnnotationAssertion(Annotation( "GOC:mah") "regulation of protein localisation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032880") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "regulation of protein localization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of polysaccharide metabolic process) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving polysaccharides.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032881") -AnnotationAssertion(rdfs:label "regulation of polysaccharide metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of chitin metabolic process) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving chitin.") -AnnotationAssertion( "regulation of chitin metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032882") -AnnotationAssertion(rdfs:label "regulation of chitin metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of chitin biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of chitin.") -AnnotationAssertion( "regulation of chitin anabolism") -AnnotationAssertion( "regulation of chitin formation") -AnnotationAssertion( "regulation of chitin synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "regulation of chitin biosynthesis") -AnnotationAssertion( "GO:0032883") -AnnotationAssertion(rdfs:label "regulation of chitin biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of polysaccharide biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of polysaccharides.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032885") -AnnotationAssertion(rdfs:label "regulation of polysaccharide biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of microtubule-based process) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of any cellular process that depends upon or alters the microtubule cytoskeleton.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032886") -AnnotationAssertion(rdfs:label "regulation of microtubule-based process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of organic acid transport) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032890") -AnnotationAssertion(rdfs:label "regulation of organic acid transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (negative regulation of organic acid transport) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion( "down regulation of organic acid transport") -AnnotationAssertion( "down-regulation of organic acid transport") -AnnotationAssertion( "downregulation of organic acid transport") -AnnotationAssertion( "inhibition of organic acid transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032891") -AnnotationAssertion(rdfs:label "negative regulation of organic acid transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of organic acid transport) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion( "up regulation of organic acid transport") -AnnotationAssertion( "up-regulation of organic acid transport") -AnnotationAssertion( "upregulation of organic acid transport") -AnnotationAssertion( "activation of organic acid transport") -AnnotationAssertion( "stimulation of organic acid transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032892") -AnnotationAssertion(rdfs:label "positive regulation of organic acid transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - # Class: (secretion by cell) AnnotationAssertion(Annotation( "GOC:mah") "The controlled release of a substance by a cell.") @@ -75046,170 +24252,8 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0032943") AnnotationAssertion(rdfs:label "mononuclear cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (regulation of mononuclear cell proliferation) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that modulates the frequency, rate or extent of mononuclear cell proliferation.") -AnnotationAssertion( "regulation of PBMC proliferation") -AnnotationAssertion( "regulation of peripheral blood mononuclear cell proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032944") -AnnotationAssertion(rdfs:label "regulation of mononuclear cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (negative regulation of mononuclear cell proliferation) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that stops, prevents, or reduces the frequency, rate or extent of mononuclear cell proliferation.") -AnnotationAssertion( "negative regulation of PBMC proliferation") -AnnotationAssertion( "negative regulation of peripheral blood mononuclear cell proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032945") -AnnotationAssertion(rdfs:label "negative regulation of mononuclear cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of mononuclear cell proliferation) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that activates or increases the frequency, rate or extent of mononuclear cell proliferation.") -AnnotationAssertion( "up regulation of mononuclear cell proliferation") -AnnotationAssertion( "up-regulation of mononuclear cell proliferation") -AnnotationAssertion( "upregulation of mononuclear cell proliferation") -AnnotationAssertion( "activation of mononuclear cell proliferation") -AnnotationAssertion( "positive regulation of PBMC proliferation") -AnnotationAssertion( "positive regulation of peripheral blood mononuclear cell proliferation") -AnnotationAssertion( "stimulation of mononuclear cell proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032946") -AnnotationAssertion(rdfs:label "positive regulation of mononuclear cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of actin cytoskeleton organization) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins.") -AnnotationAssertion(Annotation( "GOC:mah") "regulation of actin cytoskeleton organisation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:mah") "regulation of actin cytoskeleton organization and biogenesis") -AnnotationAssertion( "GO:0032956") -AnnotationAssertion(rdfs:label "regulation of actin cytoskeleton organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (collagen metabolic process) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%).") -AnnotationAssertion( "collagen metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032963") -AnnotationAssertion(rdfs:label "collagen metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (collagen biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%).") -AnnotationAssertion( "collagen anabolism") -AnnotationAssertion( "collagen biosynthesis") -AnnotationAssertion( "collagen formation") -AnnotationAssertion( "collagen synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032964") -AnnotationAssertion(rdfs:label "collagen biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of collagen biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals.") -AnnotationAssertion( "regulation of collagen anabolism") -AnnotationAssertion( "regulation of collagen biosynthesis") -AnnotationAssertion( "regulation of collagen formation") -AnnotationAssertion( "regulation of collagen synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032965") -AnnotationAssertion(rdfs:label "regulation of collagen biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of collagen biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals.") -AnnotationAssertion( "negative regulation of collagen anabolism") -AnnotationAssertion( "negative regulation of collagen biosynthesis") -AnnotationAssertion( "negative regulation of collagen formation") -AnnotationAssertion( "negative regulation of collagen synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032966") -AnnotationAssertion(rdfs:label "negative regulation of collagen biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of collagen biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals.") -AnnotationAssertion( "positive regulation of collagen anabolism") -AnnotationAssertion( "positive regulation of collagen biosynthesis") -AnnotationAssertion( "positive regulation of collagen formation") -AnnotationAssertion( "positive regulation of collagen synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032967") -AnnotationAssertion(rdfs:label "positive regulation of collagen biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of actin filament-based process) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of any cellular process that depends upon or alters the actin cytoskeleton.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032970") -AnnotationAssertion(rdfs:label "regulation of actin filament-based process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (amino acid export across plasma membrane) - -AnnotationAssertion(Annotation( "GOC:jl") "The directed movement of amino acids from inside of a cell, across the plasma membrane and into the extracellular region.") -AnnotationAssertion( "jl") -AnnotationAssertion( "2012-11-14T14:27:40Z") -AnnotationAssertion( "GO:0044746") -AnnotationAssertion( "amino acid export") -AnnotationAssertion( "amino acid transmembrane export") -AnnotationAssertion( "amino acid efflux") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032973") -AnnotationAssertion(rdfs:label "amino acid export across plasma membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (amino acid transmembrane export from vacuole) - -AnnotationAssertion(Annotation( "GOC:mah") "The directed movement of amino acids out of the vacuole, across the vacuolar membrane.") -AnnotationAssertion( "amino acid efflux from vacuole") -AnnotationAssertion( "vacuolar amino acid export") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032974") -AnnotationAssertion(rdfs:label "amino acid transmembrane export from vacuole") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (amino acid transmembrane import into vacuole) - -AnnotationAssertion(Annotation( "GOC:mah") "The directed movement of amino acids into the vacuole across the vacuolar membrane.") -AnnotationAssertion( "vacuolar amino acid import") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032975") -AnnotationAssertion(rdfs:label "amino acid transmembrane import into vacuole") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (keratinocyte activation) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "PMID:15737202") "A change in the morphology or behavior of a keratinocyte resulting from exposure to an activating factor such as a cellular or soluble ligand. Upon activation, keratinocytes become migratory and hyperproliferative, and produce growth factors and cytokines.") -AnnotationAssertion( ) -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032980") -AnnotationAssertion(rdfs:label "keratinocyte activation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) -DisjointClasses( ObjectSomeValuesFrom( )) - # Class: (protein-containing complex disassembly) AnnotationAssertion(Annotation( "GOC:mah") "The disaggregation of a protein-containing macromolecular complex into its constituent components.") @@ -75224,51 +24268,8 @@ AnnotationAssertion( "macromolecule complex disassembly") AnnotationAssertion( "GO:0032984") AnnotationAssertion(rdfs:label "protein-containing complex disassembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (protein-DNA complex disassembly) - -AnnotationAssertion(Annotation( "GOC:mah") "The disaggregation of a protein-DNA complex into its constituent components.") -AnnotationAssertion(Annotation( "GOC:mah") "DNA-protein complex disassembly") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032986") -AnnotationAssertion(rdfs:label "protein-DNA complex disassembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (protein-RNA complex disassembly) - -AnnotationAssertion(Annotation( "GOC:mah") "The disaggregation of a protein-RNA complex into its constituent components.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/25143"^^xsd:anyURI) -AnnotationAssertion( "RNA-protein complex disassembly") -AnnotationAssertion( "RNP complex disassembly") -AnnotationAssertion( "ribonucleoprotein complex disassembly") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032988") -AnnotationAssertion(rdfs:label "protein-RNA complex disassembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (cellular component morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mah") Annotation( "GOC:tb") "The process in which cellular structures, including whole cells or cell parts, are generated and organized.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/25496"^^xsd:anyURI) -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "cellular structure morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032989") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "cellular component morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cell part morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mah") "The process in which the anatomical structures of a cell part are generated and organized.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0032990") -AnnotationAssertion(rdfs:label "cell part morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (protein-containing complex) AnnotationAssertion(Annotation( "GOC:dos") Annotation( "GOC:mah") "A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.") @@ -75291,174 +24292,6 @@ SubClassOf( ObjectSomeValuesFrom( )) DisjointClasses( ) -# Class: (protein-DNA complex) - -AnnotationAssertion(Annotation( "GOC:mah") "A macromolecular complex containing both protein and DNA molecules.") -AnnotationAssertion(Annotation( "GOC:mah") "DNA-protein complex") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0032993") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "Note that this term is intended to classify complexes that have DNA as one of the members of the complex, that is, the complex does not exist if DNA is not present. Protein complexes that interact with DNA e.g. transcription factor complexes should not be classified here.") -AnnotationAssertion(rdfs:label "protein-DNA complex") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (Fc receptor complex) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") "A protein complex composed of a subunit or subunits capable of binding the Fc portion of an immunoglobulin with additional signaling components. The complex functions as a receptor for immunoglobulin.") -AnnotationAssertion( "immunoglobulin receptor complex") -AnnotationAssertion( "Fc-receptor complex") -AnnotationAssertion( "FcR complex") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0032997") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "Fc receptor complex") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (Fc-gamma receptor III complex) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") Annotation( "PMID:11244038") Annotation( "PMID:12413532") "A protein complex composed of an Fc-gamma RIII alpha chain and an Fc-epsilon RI gamma chain dimer with or without an Fc-epsilon RI beta chain and additional signaling components. The complex functions primarily as an activating receptor for IgG.") -AnnotationAssertion( "IgG receptor complex") -AnnotationAssertion( "immunoglobulin G receptor complex") -AnnotationAssertion( "FcgRIII complex") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0033001") -AnnotationAssertion(rdfs:label "Fc-gamma receptor III complex") -SubClassOf( ) - -# Class: (muscle cell proliferation) - -AnnotationAssertion(Annotation( "CL:0000187") Annotation( "GOC:mah") "The expansion of a muscle cell population by cell division.") -AnnotationAssertion( "myocyte proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0033002") -AnnotationAssertion(rdfs:label "muscle cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (tetrapyrrole metabolic process) - -AnnotationAssertion(Annotation( "GOC:mah") "The chemical reactions and pathways involving tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next.") -AnnotationAssertion( "tetrapyrrole metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0033013") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "tetrapyrrole metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (tetrapyrrole biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:mah") "The chemical reactions and pathways leading to the formation of tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next.") -AnnotationAssertion( "tetrapyrrole anabolism") -AnnotationAssertion( "tetrapyrrole biosynthesis") -AnnotationAssertion( "tetrapyrrole formation") -AnnotationAssertion( "tetrapyrrole synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0033014") -AnnotationAssertion(rdfs:label "tetrapyrrole biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (tetrapyrrole catabolic process) - -AnnotationAssertion(Annotation( "GOC:mah") "The chemical reactions and pathways leading to the breakdown of tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next.") -AnnotationAssertion( "tetrapyrrole breakdown") -AnnotationAssertion( "tetrapyrrole catabolism") -AnnotationAssertion( "tetrapyrrole degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0033015") -AnnotationAssertion(rdfs:label "tetrapyrrole catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (myeloid cell apoptotic process) - -AnnotationAssertion(Annotation( "CL:0000763") Annotation( "GOC:add") Annotation( "GOC:mtg_apoptosis") Annotation( "PMID:11292031") Annotation( "PMID:15330259") Annotation( "PMID:17133093") "Any apoptotic process in a myeloid cell, a cell of the monocyte, granulocyte, mast cell, megakaryocyte, or erythroid lineage.") -AnnotationAssertion( "apoptosis of myeloid cells") -AnnotationAssertion( "myeloid cell apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0033028") -AnnotationAssertion(rdfs:label "myeloid cell apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of neutrophil apoptotic process) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:mtg_apoptosis") "Any process that modulates the frequency, rate, or extent of neutrophil apoptotic process.") -AnnotationAssertion( "regulation of neutrophil apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0033029") -AnnotationAssertion(rdfs:label "regulation of neutrophil apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (negative regulation of neutrophil apoptotic process) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:mtg_apoptosis") "Any process that stops, prevents, or reduces the frequency, rate, or extent of neutrophil apoptotic process.") -AnnotationAssertion( "down regulation of neutrophil apoptosis") -AnnotationAssertion( "down-regulation of neutrophil apoptosis") -AnnotationAssertion( "downregulation of neutrophil apoptosis") -AnnotationAssertion( "inhibition of neutrophil apoptosis") -AnnotationAssertion( "negative regulation of neutrophil apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0033030") -AnnotationAssertion(rdfs:label "negative regulation of neutrophil apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of neutrophil apoptotic process) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:mtg_apoptosis") "Any process that activates or increases the frequency, rate, or extent of neutrophil apoptotic process.") -AnnotationAssertion( "up regulation of neutrophil apoptosis") -AnnotationAssertion( "up-regulation of neutrophil apoptosis") -AnnotationAssertion( "upregulation of neutrophil apoptosis") -AnnotationAssertion( "activation of neutrophil apoptosis") -AnnotationAssertion( "positive regulation of neutrophil apoptosis") -AnnotationAssertion( "stimulation of neutrophil apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0033031") -AnnotationAssertion(rdfs:label "positive regulation of neutrophil apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (regulation of myeloid cell apoptotic process) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:mtg_apoptosis") "Any process that modulates the frequency, rate, or extent of myeloid cell apoptotic process.") -AnnotationAssertion( "regulation of myeloid cell apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0033032") -AnnotationAssertion(rdfs:label "regulation of myeloid cell apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of myeloid cell apoptotic process) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:mtg_apoptosis") "Any process that stops, prevents, or reduces the frequency, rate, or extent of a myeloid cell apoptotic process.") -AnnotationAssertion( "down regulation of myeloid cell apoptosis") -AnnotationAssertion( "down-regulation of myeloid cell apoptosis") -AnnotationAssertion( "downregulation of myeloid cell apoptosis") -AnnotationAssertion( "inhibition of myeloid cell apoptosis") -AnnotationAssertion( "negative regulation of myeloid cell apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0033033") -AnnotationAssertion(rdfs:label "negative regulation of myeloid cell apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of myeloid cell apoptotic process) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:mtg_apoptosis") "Any process that activates or increases the frequency, rate, or extent of myeloid cell apoptotic process.") -AnnotationAssertion( "up regulation of myeloid cell apoptosis") -AnnotationAssertion( "up-regulation of myeloid cell apoptosis") -AnnotationAssertion( "upregulation of myeloid cell apoptosis") -AnnotationAssertion( "activation of myeloid cell apoptosis") -AnnotationAssertion( "positive regulation of myeloid cell apoptosis") -AnnotationAssertion( "stimulation of myeloid cell apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0033034") -AnnotationAssertion(rdfs:label "positive regulation of myeloid cell apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (macromolecule localization) AnnotationAssertion(Annotation( "GOC:mah") "Any process in which a macromolecule is transported to, or maintained in, a specific location.") @@ -75469,985 +24302,6 @@ AnnotationAssertion( "macromolecule localization") SubClassOf( ) -# Class: (polysaccharide localization) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process in which a polysaccharide is transported to, or maintained in, a specific location.") -AnnotationAssertion(Annotation( "GOC:mah") "polysaccharide localisation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0033037") -AnnotationAssertion(rdfs:label "polysaccharide localization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of organelle organization) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle.") -AnnotationAssertion(Annotation( "GOC:mah") "regulation of organelle organisation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:mah") "regulation of organelle organization and biogenesis") -AnnotationAssertion( "GO:0033043") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "regulation of organelle organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of chromosome organization) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a chromosome.") -AnnotationAssertion(Annotation( "GOC:mah") "regulation of chromosome organisation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:mah") "regulation of chromosome organization and biogenesis") -AnnotationAssertion( "GO:0033044") -AnnotationAssertion(rdfs:label "regulation of chromosome organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of sister chromatid segregation) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of sister chromatid segregation.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0033045") -AnnotationAssertion(rdfs:label "regulation of sister chromatid segregation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of sister chromatid segregation) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of sister chromatid segregation.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0033046") -AnnotationAssertion(rdfs:label "negative regulation of sister chromatid segregation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of mitotic sister chromatid segregation) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of sister chromatid segregation during mitosis.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0033047") -AnnotationAssertion(rdfs:label "regulation of mitotic sister chromatid segregation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of mitotic sister chromatid segregation) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of sister chromatid segregation during mitosis.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0033048") -AnnotationAssertion(rdfs:label "negative regulation of mitotic sister chromatid segregation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (D-glutamate metabolic process) - -AnnotationAssertion(Annotation( "GOC:jsg") Annotation( "GOC:mah") "The chemical reactions and pathways involving D-glutamate, the D-enantiomer of the amino acid glutamate, i.e. (2R)-2-aminopentanedioic acid.") -AnnotationAssertion( "D-glutamate metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0033054") -AnnotationAssertion(rdfs:label "D-glutamate metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cellular pigmentation) - -AnnotationAssertion(Annotation( "GOC:mtg_MIT_16mar07") "The deposition or aggregation of coloring matter in a cell.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0033059") -AnnotationAssertion(rdfs:label "cellular pigmentation") -SubClassOf( ) -SubClassOf( ) - -# Class: (T cell differentiation in thymus) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") "The process in which a precursor cell type acquires the specialized features of a T cell via a differentiation pathway dependent upon transit through the thymus.") -AnnotationAssertion( "thymic T cell differentiation") -AnnotationAssertion( "thymocyte cell differentiation") -AnnotationAssertion( "thymocyte differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:add") "T cell development in thymus") -AnnotationAssertion( "GO:0033077") -AnnotationAssertion(rdfs:comment "Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.") -AnnotationAssertion(rdfs:label "T cell differentiation in thymus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (immature T cell proliferation) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") "The expansion of an immature T cell population by cell division.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0033079") -AnnotationAssertion(rdfs:label "immature T cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (immature T cell proliferation in thymus) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") "The expansion of an immature T cell population by cell division in the thymus.") -AnnotationAssertion( "thymic T cell proliferation") -AnnotationAssertion( "thymocyte cell proliferation") -AnnotationAssertion( "thymocyte proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0033080") -AnnotationAssertion(rdfs:label "immature T cell proliferation in thymus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (regulation of T cell differentiation in thymus) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of T cell differentiation in the thymus.") -AnnotationAssertion( "regulation of thymic T cell differentiation") -AnnotationAssertion( "regulation of thymocyte cell differentiation") -AnnotationAssertion( "regulation of thymocyte differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:add") "regulation of T cell development in thymus") -AnnotationAssertion( "GO:0033081") -AnnotationAssertion(rdfs:comment "Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.") -AnnotationAssertion(rdfs:label "regulation of T cell differentiation in thymus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of immature T cell proliferation) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of immature T cell proliferation.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0033083") -AnnotationAssertion(rdfs:label "regulation of immature T cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of immature T cell proliferation in thymus) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of immature T cell proliferation in the thymus.") -AnnotationAssertion( "regulation of thymic T cell proliferation") -AnnotationAssertion( "regulation of thymocyte cell proliferation") -AnnotationAssertion( "regulation of thymocyte proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0033084") -AnnotationAssertion(rdfs:comment "Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.") -AnnotationAssertion(rdfs:label "regulation of immature T cell proliferation in thymus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of T cell differentiation in thymus) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of T cell differentiation in the thymus.") -AnnotationAssertion( "negative regulation of thymic T cell differentiation") -AnnotationAssertion( "negative regulation of thymocyte cell differentiation") -AnnotationAssertion( "negative regulation of thymocyte differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:add") "negative regulation of T cell development in thymus") -AnnotationAssertion( "GO:0033085") -AnnotationAssertion(rdfs:comment "Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.") -AnnotationAssertion(rdfs:label "negative regulation of T cell differentiation in thymus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of immature T cell proliferation) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of immature T cell proliferation.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0033087") -AnnotationAssertion(rdfs:label "negative regulation of immature T cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of immature T cell proliferation in thymus) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of immature T cell proliferation in the thymus.") -AnnotationAssertion( "negative regulation of thymic T cell proliferation") -AnnotationAssertion( "negative regulation of thymocyte cell proliferation") -AnnotationAssertion( "negative regulation of thymocyte proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0033088") -AnnotationAssertion(rdfs:label "negative regulation of immature T cell proliferation in thymus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of T cell differentiation in thymus) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of T cell differentiation in the thymus.") -AnnotationAssertion( "positive regulation of thymic T cell differentiation") -AnnotationAssertion( "positive regulation of thymocyte cell differentiation") -AnnotationAssertion( "positive regulation of thymocyte differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:add") "positive regulation of T cell development in thymus") -AnnotationAssertion( "GO:0033089") -AnnotationAssertion(rdfs:comment "Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.") -AnnotationAssertion(rdfs:label "positive regulation of T cell differentiation in thymus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of immature T cell proliferation) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of immature T cell proliferation.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0033091") -AnnotationAssertion(rdfs:label "positive regulation of immature T cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of immature T cell proliferation in thymus) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of immature T cell proliferation in the thymus.") -AnnotationAssertion( "positive regulation of thymic T cell proliferation") -AnnotationAssertion( "positive regulation of thymocyte cell proliferation") -AnnotationAssertion( "positive regulation of thymocyte proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0033092") -AnnotationAssertion(rdfs:label "positive regulation of immature T cell proliferation in thymus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of purine nucleotide catabolic process) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of purine nucleotides.") -AnnotationAssertion( "regulation of purine nucleotide breakdown") -AnnotationAssertion( "regulation of purine nucleotide catabolism") -AnnotationAssertion( "regulation of purine nucleotide degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0033121") -AnnotationAssertion(rdfs:label "regulation of purine nucleotide catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of purine nucleotide catabolic process) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of purine nucleotides.") -AnnotationAssertion( "negative regulation of purine nucleotide breakdown") -AnnotationAssertion( "negative regulation of purine nucleotide catabolism") -AnnotationAssertion( "negative regulation of purine nucleotide degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0033122") -AnnotationAssertion(rdfs:label "negative regulation of purine nucleotide catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of purine nucleotide catabolic process) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of purine nucleotides.") -AnnotationAssertion( "positive regulation of purine nucleotide breakdown") -AnnotationAssertion( "positive regulation of purine nucleotide catabolism") -AnnotationAssertion( "positive regulation of purine nucleotide degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0033123") -AnnotationAssertion(rdfs:label "positive regulation of purine nucleotide catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of intracellular steroid hormone receptor signaling pathway) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the activity of any intracellular steroid hormone receptor signaling pathway.") -AnnotationAssertion(Annotation( "GOC:bf") "regulation of steroid hormone receptor signaling pathway") -AnnotationAssertion( "regulation of steroid hormone receptor signalling pathway") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0033143") -AnnotationAssertion(rdfs:label "regulation of intracellular steroid hormone receptor signaling pathway") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of intracellular steroid hormone receptor signaling pathway) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of any intracellular steroid hormone receptor signaling pathway.") -AnnotationAssertion(Annotation( "GOC:bf") "negative regulation of steroid hormone receptor signaling pathway") -AnnotationAssertion(Annotation( "GOC:bf") "negative regulation of steroid hormone receptor signalling pathway") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0033144") -AnnotationAssertion(rdfs:label "negative regulation of intracellular steroid hormone receptor signaling pathway") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of intracellular steroid hormone receptor signaling pathway) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of the activity of any intracellular steroid hormone receptor signaling pathway.") -AnnotationAssertion(Annotation( "GOC:bf") "positive regulation of steroid hormone receptor signaling pathway") -AnnotationAssertion( "positive regulation of steroid hormone receptor signalling pathway") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0033145") -AnnotationAssertion(rdfs:label "positive regulation of intracellular steroid hormone receptor signaling pathway") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (V(D)J recombination) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781700221") Annotation( "ISBN:0781735149") "The process in which immune receptor V, D, and J, or V and J gene segments, depending on the specific receptor, are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS).") -AnnotationAssertion( "Wikipedia:V(D)J_recombination") -AnnotationAssertion( "V(D)J joining") -AnnotationAssertion( "V-D-J joining") -AnnotationAssertion( "V-D-J recombination") -AnnotationAssertion( "V-J joining") -AnnotationAssertion( "V-J recombination") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0033151") -AnnotationAssertion(rdfs:label "V(D)J recombination") -SubClassOf( ) - -# Class: (immunoglobulin V(D)J recombination) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") "The process in which immunoglobulin gene segments are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS). For immunoglobulin heavy chains V, D, and J gene segments are joined, and for immunoglobulin light chains V and J gene segments are joined.") -AnnotationAssertion(Annotation( "GOC:add") "immunoglobulin V(D)J joining") -AnnotationAssertion(Annotation( "GOC:add") "immunoglobulin V-D-J joining") -AnnotationAssertion(Annotation( "GOC:add") "immunoglobulin V-D-J recombination") -AnnotationAssertion(Annotation( "GOC:add") "immunoglobulin V-J joining") -AnnotationAssertion(Annotation( "GOC:add") "immunoglobulin V-J recombination") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0033152") -AnnotationAssertion(rdfs:label "immunoglobulin V(D)J recombination") -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of intracellular protein transport) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the directed movement of proteins within cells.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0033157") -AnnotationAssertion(rdfs:label "regulation of intracellular protein transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (melanosome membrane) - -AnnotationAssertion(Annotation( "GOC:mah") "The lipid bilayer surrounding a melanosome.") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0033162") -AnnotationAssertion(rdfs:label "melanosome membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (response to ATP) - -AnnotationAssertion(Annotation( "GOC:sl") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ATP (adenosine 5'-triphosphate) stimulus.") -AnnotationAssertion( "response to adenosine 5'-triphosphate") -AnnotationAssertion( "response to adenosine triphosphate") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0033198") -AnnotationAssertion(rdfs:label "response to ATP") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (iron import into cell) - -AnnotationAssertion(Annotation( "PMID:18622392") Annotation( "PMID:23192658") Annotation( "Wikipedia:Human_iron_metabolism") "The directed movement of iron ions from outside of a cell into the cytoplasmic compartment. This may occur via transport across the plasma membrane or via endocytosis.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2009-05-01T04:19:14Z") -AnnotationAssertion( "GO:0070627") -AnnotationAssertion( "ferrous ion import") -AnnotationAssertion( "ferrous iron import") -AnnotationAssertion( "ferrous iron uptake") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "iron assimilation") -AnnotationAssertion( "GO:0033212") -AnnotationAssertion(rdfs:label "iron import into cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (amide binding) - -AnnotationAssertion(Annotation( "GOC:mah") "Binding to an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0033218") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "amide binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of amine metabolic process) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform amines.") -AnnotationAssertion( "regulation of amine metabolism") -AnnotationAssertion( "regulation of cellular amine metabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0033238") -AnnotationAssertion(rdfs:label "regulation of amine metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of amine metabolic process) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amines.") -AnnotationAssertion( "negative regulation of amine metabolism") -AnnotationAssertion( "negative regulation of cellular amine metabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0033239") -AnnotationAssertion(rdfs:label "negative regulation of amine metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of amine metabolic process) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amines.") -AnnotationAssertion( "positive regulation of amine metabolism") -AnnotationAssertion( "positive regulation of cellular amine metabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0033240") -AnnotationAssertion(rdfs:label "positive regulation of amine metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of amine catabolic process) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines.") -AnnotationAssertion( "regulation of amine breakdown") -AnnotationAssertion( "regulation of amine catabolism") -AnnotationAssertion( "regulation of amine degradation") -AnnotationAssertion( "regulation of cellular amine catabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0033241") -AnnotationAssertion(rdfs:label "regulation of amine catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of amine catabolic process) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines.") -AnnotationAssertion( "negative regulation of amine breakdown") -AnnotationAssertion( "negative regulation of amine catabolism") -AnnotationAssertion( "negative regulation of amine degradation") -AnnotationAssertion( "negative regulation of cellular amine catabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0033242") -AnnotationAssertion(rdfs:label "negative regulation of amine catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of amine catabolic process) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines.") -AnnotationAssertion( "positive regulation of amine breakdown") -AnnotationAssertion( "positive regulation of amine catabolism") -AnnotationAssertion( "positive regulation of amine degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0033243") -AnnotationAssertion(rdfs:label "positive regulation of amine catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (choline binding) - -AnnotationAssertion(Annotation( "GOC:mlg") "Binding to choline, the amine 2-hydroxy-N,N,N-trimethylethanaminium.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0033265") -AnnotationAssertion(rdfs:label "choline binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cell proliferation in midbrain) - -AnnotationAssertion(Annotation( "GOC:dgf") Annotation( "GO_REF:0000021") "The multiplication or reproduction of cells, resulting in the expansion of a cell population in the midbrain.") -AnnotationAssertion( "cell proliferation in mesencephalon") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "mesencepahalic cell proliferation") -AnnotationAssertion( "GO:0033278") -AnnotationAssertion(rdfs:label "cell proliferation in midbrain") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (monocarboxylic acid binding) - -AnnotationAssertion(Annotation( "GOC:mah") "Binding to a monocarboxylic acid, any organic acid containing one carboxyl (COOH) group or anion (COO-).") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0033293") -AnnotationAssertion(rdfs:label "monocarboxylic acid binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (Leydig cell differentiation) - -AnnotationAssertion(Annotation( "GOC:ln") Annotation( "PMID:12050120") "The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a Leydig cell. A Leydig cell is a testosterone-secreting cell in the interstitial area, between the seminiferous tubules, in the testis.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0033327") -AnnotationAssertion(rdfs:label "Leydig cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (fin development) - -AnnotationAssertion(Annotation( "GOC:dgh") "The process whose specific outcome is the progression of a fin over time, from its formation to the mature structure.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0033333") -AnnotationAssertion(rdfs:label "fin development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (fin morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dgh") "The process in which the anatomical structures of a fin are generated and organized.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0033334") -AnnotationAssertion(rdfs:label "fin morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (anal fin development) - -AnnotationAssertion(Annotation( "GOC:dgh") "The process whose specific outcome is the progression of the anal fin over time, from its formation to the mature structure.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0033335") -AnnotationAssertion(rdfs:label "anal fin development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (caudal fin development) - -AnnotationAssertion(Annotation( "GOC:dgh") "The process whose specific outcome is the progression of the caudal fin over time, from its formation to the mature structure.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0033336") -AnnotationAssertion(rdfs:label "caudal fin development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (dorsal fin development) - -AnnotationAssertion(Annotation( "GOC:dgh") "The process whose specific outcome is the progression of the dorsal fin over time, from its formation to the mature structure.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0033337") -AnnotationAssertion(rdfs:label "dorsal fin development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (medial fin development) - -AnnotationAssertion(Annotation( "GOC:dgh") "The process whose specific outcome is the progression of a medial fin over time, from its formation to the mature structure.") -AnnotationAssertion( "median fin development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0033338") -AnnotationAssertion(rdfs:label "medial fin development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (pectoral fin development) - -AnnotationAssertion(Annotation( "GOC:dgh") "The process whose specific outcome is the progression of the pectoral fin over time, from its formation to the mature structure.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0033339") -AnnotationAssertion(rdfs:label "pectoral fin development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (pelvic fin development) - -AnnotationAssertion(Annotation( "GOC:dgh") "The process whose specific outcome is the progression of the pelvic fin over time, from its formation to the mature structure.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0033340") -AnnotationAssertion(rdfs:label "pelvic fin development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of collagen binding) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of collagen binding.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0033341") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "regulation of collagen binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of collagen binding) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of collagen binding.") -AnnotationAssertion( "down regulation of collagen binding") -AnnotationAssertion( "down-regulation of collagen binding") -AnnotationAssertion( "downregulation of collagen binding") -AnnotationAssertion( "inhibition of collagen binding") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0033342") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "negative regulation of collagen binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of collagen binding) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of collagen binding.") -AnnotationAssertion( "up regulation of collagen binding") -AnnotationAssertion( "up-regulation of collagen binding") -AnnotationAssertion( "upregulation of collagen binding") -AnnotationAssertion( "activation of collagen binding") -AnnotationAssertion( "stimulation of collagen binding") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0033343") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "positive regulation of collagen binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (secretory granule organization) - -AnnotationAssertion(Annotation( "GOC:mah") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a secretory granule. A secretory granule is a small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion.") -AnnotationAssertion(Annotation( "GOC:mah") "secretory granule organisation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:mah") "secretory granule organization and biogenesis") -AnnotationAssertion( "GO:0033363") -AnnotationAssertion(rdfs:label "secretory granule organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (protein localization to organelle) - -AnnotationAssertion(Annotation( "GOC:mah") "A process in which a protein is transported to, or maintained in, a location within an organelle.") -AnnotationAssertion(Annotation( "GOC:mah") "protein localisation to organelle") -AnnotationAssertion(Annotation( "GOC:mah") "protein localization in organelle") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0033365") -AnnotationAssertion(rdfs:label "protein localization to organelle") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (protein localization to secretory granule) - -AnnotationAssertion(Annotation( "GOC:mah") "A process in which a protein is transported to, or maintained in, a location within a secretory granule.") -AnnotationAssertion(Annotation( "GOC:mah") "protein localisation in secretory granule") -AnnotationAssertion( "protein localization in secretory granule") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0033366") -AnnotationAssertion(rdfs:label "protein localization to secretory granule") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (T cell secretory granule organization) - -AnnotationAssertion(Annotation( "GOC:mah") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a secretory granule in a T cell. A secretory granule is a small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion.") -AnnotationAssertion(Annotation( "GOC:mah") "T cell secretory granule organisation") -AnnotationAssertion( "T lymphocyte secretory granule organization") -AnnotationAssertion( "T-cell secretory granule organization") -AnnotationAssertion( "T-lymphocyte secretory granule organization") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:mah") "T cell secretory granule organization and biogenesis") -AnnotationAssertion( "T-lymphocyte secretory granule maturation") -AnnotationAssertion( "GO:0033371") -AnnotationAssertion(rdfs:label "T cell secretory granule organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (carbohydrate homeostasis) - -AnnotationAssertion(Annotation( "GOC:mah") "A homeostatic process involved in the maintenance of an internal steady state of a carbohydrate within an organism or cell.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0033500") -AnnotationAssertion(rdfs:label "carbohydrate homeostasis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (floor plate development) - -AnnotationAssertion(Annotation( "GOC:dh") "The progression of the floor plate over time from its initial formation until its mature state.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0033504") -AnnotationAssertion(rdfs:label "floor plate development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (floor plate morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dh") "The process in which the anatomical structure of the floor plate is generated and organized.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0033505") -AnnotationAssertion(rdfs:label "floor plate morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (glutamate catabolic process to butyrate) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "MetaCyc:PWY-5087") "The chemical reactions and pathways resulting in the breakdown of glutamate into other compounds, including butyrate.") -AnnotationAssertion( "MetaCyc:PWY-5087") -AnnotationAssertion( "glutamate breakdown to butyrate") -AnnotationAssertion( "glutamate degradation to butyrate") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0033508") -AnnotationAssertion(rdfs:label "glutamate catabolic process to butyrate") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (tetrapyrrole biosynthetic process from glutamate) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "MetaCyc:PWY-5188") "The chemical reactions and pathways leading to the formation of tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next, from other compounds, including L-glutamate.") -AnnotationAssertion( "MetaCyc:PWY-5188") -AnnotationAssertion( "tetrapyrrole anabolism from glutamate") -AnnotationAssertion( "tetrapyrrole biosynthesis from glutamate") -AnnotationAssertion( "tetrapyrrole formation from glutamate") -AnnotationAssertion( "tetrapyrrole synthesis from glutamate") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0033526") -AnnotationAssertion(rdfs:label "tetrapyrrole biosynthetic process from glutamate") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (lactoferrin transmembrane transporter activity) - -AnnotationAssertion(Annotation( "GOC:mlg") "Enables the transfer of lactoferrin from one side of a membrane to the other.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0033569") -AnnotationAssertion(rdfs:label "lactoferrin transmembrane transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (lactoferrin transport) - -AnnotationAssertion(Annotation( "GOC:mlg") "The directed movement of lactoferrin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0033571") -AnnotationAssertion(rdfs:label "lactoferrin transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (response to testosterone) - -AnnotationAssertion(Annotation( "GOC:sl") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a testosterone stimulus.") -AnnotationAssertion(Annotation( "GOC:dos") "response to testosterone stimulus") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0033574") -AnnotationAssertion(rdfs:label "response to testosterone") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of dopamine secretion) - -AnnotationAssertion(Annotation( "GOC:sl") "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of dopamine.") -AnnotationAssertion( "down regulation of dopamine secretion") -AnnotationAssertion( "down-regulation of dopamine secretion") -AnnotationAssertion( "downregulation of dopamine secretion") -AnnotationAssertion( "inhibition of dopamine secretion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0033602") -AnnotationAssertion(rdfs:label "negative regulation of dopamine secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of dopamine secretion) - -AnnotationAssertion(Annotation( "GOC:sl") "Any process that activates or increases the frequency, rate or extent of the regulated release of dopamine.") -AnnotationAssertion( "up regulation of dopamine secretion") -AnnotationAssertion( "up-regulation of dopamine secretion") -AnnotationAssertion( "upregulation of dopamine secretion") -AnnotationAssertion( "activation of dopamine secretion") -AnnotationAssertion( "stimulation of dopamine secretion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0033603") -AnnotationAssertion(rdfs:label "positive regulation of dopamine secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of catecholamine secretion) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a catecholamine.") -AnnotationAssertion( "down regulation of catecholamine secretion") -AnnotationAssertion( "down-regulation of catecholamine secretion") -AnnotationAssertion( "downregulation of catecholamine secretion") -AnnotationAssertion( "inhibition of catecholamine secretion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0033604") -AnnotationAssertion(rdfs:label "negative regulation of catecholamine secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of catecholamine secretion) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of the regulated release of a catecholamine.") -AnnotationAssertion( "up regulation of catecholamine secretion") -AnnotationAssertion( "up-regulation of catecholamine secretion") -AnnotationAssertion( "upregulation of catecholamine secretion") -AnnotationAssertion( "activation of catecholamine secretion") -AnnotationAssertion( "stimulation of catecholamine secretion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0033605") -AnnotationAssertion(rdfs:label "positive regulation of catecholamine secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of kinase activity) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.") -AnnotationAssertion( "down regulation of kinase activity") -AnnotationAssertion( "down-regulation of kinase activity") -AnnotationAssertion( "downregulation of kinase activity") -AnnotationAssertion( "inhibition of kinase activity") -AnnotationAssertion( "kinase inhibitor") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0033673") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "negative regulation of kinase activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of kinase activity) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.") -AnnotationAssertion( "up regulation of kinase activity") -AnnotationAssertion( "up-regulation of kinase activity") -AnnotationAssertion( "upregulation of kinase activity") -AnnotationAssertion( "kinase activator") -AnnotationAssertion( "stimulation of kinase activity") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0033674") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "positive regulation of kinase activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (regulation of luteinizing hormone secretion) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the regulated release of luteinizing hormone.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0033684") -AnnotationAssertion(rdfs:label "regulation of luteinizing hormone secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of luteinizing hormone secretion) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of luteinizing hormone.") -AnnotationAssertion( "down regulation of luteinizing hormone secretion") -AnnotationAssertion( "down-regulation of luteinizing hormone secretion") -AnnotationAssertion( "downregulation of luteinizing hormone secretion") -AnnotationAssertion( "inhibition of luteinizing hormone secretion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0033685") -AnnotationAssertion(rdfs:label "negative regulation of luteinizing hormone secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of luteinizing hormone secretion) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of the regulated release of luteinizing hormone.") -AnnotationAssertion( "up regulation of luteinizing hormone secretion") -AnnotationAssertion( "up-regulation of luteinizing hormone secretion") -AnnotationAssertion( "upregulation of luteinizing hormone secretion") -AnnotationAssertion( "activation of luteinizing hormone secretion") -AnnotationAssertion( "stimulation of luteinizing hormone secretion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0033686") -AnnotationAssertion(rdfs:label "positive regulation of luteinizing hormone secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (osteoblast proliferation) - -AnnotationAssertion(Annotation( "GOC:mah") "The multiplication or reproduction of osteoblasts, resulting in the expansion of an osteoblast cell population. An osteoblast is a bone-forming cell which secretes an extracellular matrix. Hydroxyapatite crystals are then deposited into the matrix to form bone.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0033687") -AnnotationAssertion(rdfs:label "osteoblast proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of osteoblast proliferation) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of osteoblast proliferation.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0033688") -AnnotationAssertion(rdfs:label "regulation of osteoblast proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of osteoblast proliferation) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents or reduces the rate or extent of osteoblast proliferation.") -AnnotationAssertion( "down regulation of osteoblast proliferation") -AnnotationAssertion( "down-regulation of osteoblast proliferation") -AnnotationAssertion( "downregulation of osteoblast proliferation") -AnnotationAssertion( "inhibition of osteoblast proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0033689") -AnnotationAssertion(rdfs:label "negative regulation of osteoblast proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of osteoblast proliferation) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the rate or extent of osteoblast proliferation.") -AnnotationAssertion( "up regulation of osteoblast proliferation") -AnnotationAssertion( "up-regulation of osteoblast proliferation") -AnnotationAssertion( "upregulation of osteoblast proliferation") -AnnotationAssertion( "activation of osteoblast proliferation") -AnnotationAssertion( "stimulation of osteoblast proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0033690") -AnnotationAssertion(rdfs:label "positive regulation of osteoblast proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (ribosome localization) - -AnnotationAssertion(Annotation( "GOC:mah") "A process in which a ribosome is transported to, and/or maintained in, a specific location.") -AnnotationAssertion( "GO:0033753") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "establishment of ribosome localisation") -AnnotationAssertion( "establishment of ribosome localization") -AnnotationAssertion( "ribosome localisation") -AnnotationAssertion( "GO:0033750") -AnnotationAssertion(rdfs:label "ribosome localization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (response to glucagon) - -AnnotationAssertion(Annotation( "GOC:sl") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucagon stimulus.") -AnnotationAssertion(Annotation( "GOC:dos") "response to glucagon stimulus") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0033762") -AnnotationAssertion(rdfs:label "response to glucagon") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (response to lipid) - -AnnotationAssertion(Annotation( "GOC:sl") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid stimulus.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0033993") -AnnotationAssertion(rdfs:label "response to lipid") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (protein localization to Golgi apparatus) - -AnnotationAssertion(Annotation( "GOC:mah") "A process in which a protein is transported to, or maintained in, a location within the Golgi apparatus.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2011-02-14T02:26:36Z") -AnnotationAssertion( "GO:0000042") -AnnotationAssertion( "GO:0072600") -AnnotationAssertion(Annotation( "GOC:mah") "protein localisation in Golgi apparatus") -AnnotationAssertion( "protein localization in Golgi apparatus") -AnnotationAssertion(Annotation( "GOC:mah") "establishment of protein localisation to Golgi") -AnnotationAssertion( "establishment of protein localization in Golgi") -AnnotationAssertion( "establishment of protein localization to Golgi") -AnnotationAssertion(Annotation( "GOC:mah") "establishment of protein localization to Golgi apparatus") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "protein targeting to Golgi") -AnnotationAssertion( "protein-Golgi targeting") -AnnotationAssertion( "GO:0034067") -AnnotationAssertion(rdfs:label "protein localization to Golgi apparatus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (response to cytokine) - -AnnotationAssertion(Annotation( "GOC:sl") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokine stimulus.") -AnnotationAssertion(Annotation( "GOC:dos") "response to cytokine stimulus") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0034097") -AnnotationAssertion(rdfs:label "response to cytokine") -SubClassOf( ) - -# Class: (erythrocyte homeostasis) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "PMID:10694114") Annotation( "PMID:14754397") "Any process of regulating the production and elimination of erythrocytes within an organism.") -AnnotationAssertion(Annotation( "CL:0000232") "RBC homeostasis") -AnnotationAssertion(Annotation( "CL:0000232") "red blood cell homeostasis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0034101") -AnnotationAssertion(rdfs:label "erythrocyte homeostasis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of tissue remodeling) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that modulates the frequency, rate, or extent of tissue remodeling.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0034103") -AnnotationAssertion(rdfs:label "regulation of tissue remodeling") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of tissue remodeling) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that stops, prevents, or reduces the frequency, rate, or extent of tissue remodeling.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0034104") -AnnotationAssertion(rdfs:label "negative regulation of tissue remodeling") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of tissue remodeling) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that activates or increases the frequency, rate, or extent of tissue remodeling.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0034105") -AnnotationAssertion(rdfs:label "positive regulation of tissue remodeling") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (apolipoprotein binding) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:rl") "Binding to an apolipoprotein, the protein component of a lipoprotein complex.") -AnnotationAssertion( ) -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0034185") -AnnotationAssertion(rdfs:label "apolipoprotein binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) -DisjointClasses( ObjectSomeValuesFrom( )) - -# Class: (carbohydrate transmembrane transport) - -AnnotationAssertion(Annotation( "GOC:mah") "The process in which a carbohydrate is transported across a membrane.") -AnnotationAssertion( "carbohydrate membrane transport") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "transmembrane carbohydrate transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0034219") -AnnotationAssertion(rdfs:comment "Note that this term is not intended for use in annotating lateral movement within membranes.") -AnnotationAssertion(rdfs:label "carbohydrate transmembrane transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - # Class: (monoatomic ion transmembrane transport) AnnotationAssertion(Annotation( "GOC:mah") "A process in which a monoatomic ion is transported across a membrane. Monatomic ions (also called simple ions) are ions consisting of exactly one atom.") @@ -76460,343 +24314,6 @@ AnnotationAssertion( "GO:0034220") AnnotationAssertion(rdfs:comment "Note that this term is not intended for use in annotating lateral movement within membranes.") AnnotationAssertion(rdfs:label "monoatomic ion transmembrane transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of syncytium formation by plasma membrane fusion) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that decreases the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0034242") -AnnotationAssertion(rdfs:label "negative regulation of syncytium formation by plasma membrane fusion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of amide metabolic process) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amides.") -AnnotationAssertion( "regulation of amide metabolism") -AnnotationAssertion( "regulation of cellular amide metabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0034248") -AnnotationAssertion(rdfs:label "regulation of amide metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of amide metabolic process) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amides.") -AnnotationAssertion( "negative regulation of amide metabolism") -AnnotationAssertion( "negative regulation of cellular amide metabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0034249") -AnnotationAssertion(rdfs:label "negative regulation of amide metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of amide metabolic process) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amides.") -AnnotationAssertion( "positive regulation of amide metabolism") -AnnotationAssertion( "positive regulation of cellular amide metabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0034250") -AnnotationAssertion(rdfs:label "positive regulation of amide metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of amide catabolic process) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of amides.") -AnnotationAssertion( "regulation of amide breakdown") -AnnotationAssertion( "regulation of amide catabolism") -AnnotationAssertion( "regulation of amide degradation") -AnnotationAssertion( "regulation of cellular amide catabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0034251") -AnnotationAssertion(rdfs:label "regulation of amide catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of amide catabolic process) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of amides.") -AnnotationAssertion( "negative regulation of amide breakdown") -AnnotationAssertion( "negative regulation of amide catabolism") -AnnotationAssertion( "negative regulation of cellular amide catabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "negative regulation of amide degradation") -AnnotationAssertion( "GO:0034252") -AnnotationAssertion(rdfs:label "negative regulation of amide catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of amide catabolic process) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of amides.") -AnnotationAssertion( "positive regulation of amide breakdown") -AnnotationAssertion( "positive regulation of amide catabolism") -AnnotationAssertion( "positive regulation of cellular amide catabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "positive regulation of amide degradation") -AnnotationAssertion( "GO:0034253") -AnnotationAssertion(rdfs:label "positive regulation of amide catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (response to monosaccharide) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monosaccharide stimulus.") -AnnotationAssertion(Annotation( "GOC:dos") "response to monosaccharide stimulus") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0034284") -AnnotationAssertion(rdfs:label "response to monosaccharide") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (primary alcohol metabolic process) - -AnnotationAssertion(Annotation( "GOC:mah") "The chemical reactions and pathways involving primary alcohols. A primary alcohol is any alcohol in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it.") -AnnotationAssertion( "monohydric alcohol metabolic process") -AnnotationAssertion(Annotation( "GOC:mah") "primary alcohol metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0034308") -AnnotationAssertion(rdfs:label "primary alcohol metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (primary alcohol biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:mah") "The chemical reactions and pathways resulting in the formation of primary alcohols. A primary alcohol is any alcohol in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it.") -AnnotationAssertion( "monohydric alcohol biosynthetic process") -AnnotationAssertion(Annotation( "GOC:mah") "primary alcohol anabolism") -AnnotationAssertion(Annotation( "GOC:mah") "primary alcohol biosynthesis") -AnnotationAssertion(Annotation( "GOC:mah") "primary alcohol formation") -AnnotationAssertion(Annotation( "GOC:mah") "primary alcohol synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0034309") -AnnotationAssertion(rdfs:label "primary alcohol biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (primary alcohol catabolic process) - -AnnotationAssertion(Annotation( "GOC:mah") "The chemical reactions and pathways resulting in the breakdown of primary alcohols. A primary alcohol is any alcohol in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it.") -AnnotationAssertion( "monohydric alcohol catabolic process") -AnnotationAssertion(Annotation( "GOC:mah") "primary alcohol breakdown") -AnnotationAssertion(Annotation( "GOC:mah") "primary alcohol catabolism") -AnnotationAssertion(Annotation( "GOC:mah") "primary alcohol degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0034310") -AnnotationAssertion(rdfs:label "primary alcohol catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cell junction assembly) - -AnnotationAssertion(Annotation( "GOC:mah") "A cellular process that results in the aggregation, arrangement and bonding together of a set of components to form a cell junction.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0034329") -AnnotationAssertion(rdfs:label "cell junction assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cell junction organization) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:jl") Annotation( "GOC:mah") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cell junction. A cell junction is a specialized region of connection between two cells or between a cell and the extracellular matrix.") -AnnotationAssertion( "cell junction assembly and maintenance") -AnnotationAssertion(Annotation( "GOC:mah") "cell junction organisation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "cell junction biogenesis") -AnnotationAssertion( "GO:0034330") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "cell junction organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (glial cell apoptotic process) - -AnnotationAssertion(Annotation( "CL:0000125") Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:sart") "Any apoptotic process in a glial cell, a non-neuronal cell of the nervous system.") -AnnotationAssertion( "apoptosis of glia") -AnnotationAssertion( "apoptosis of glial cells") -AnnotationAssertion( "glia apoptosis") -AnnotationAssertion( "glia programmed cell death by apoptosis") -AnnotationAssertion( "glial cell programmed cell death by apoptosis") -AnnotationAssertion( "programmed cell death of glia by apoptosis") -AnnotationAssertion( "programmed cell death of glial cells by apoptosis") -AnnotationAssertion( "programmed cell death, glia") -AnnotationAssertion( "programmed cell death, glial cells") -AnnotationAssertion( "glial cell apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0034349") -AnnotationAssertion(rdfs:label "glial cell apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of glial cell apoptotic process) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:mtg_apoptosis") "Any process that modulates the frequency, rate, or extent of glial cell apoptotic process.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "regulation of glial cell apoptosis") -AnnotationAssertion( "GO:0034350") -AnnotationAssertion(rdfs:label "regulation of glial cell apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of glial cell apoptotic process) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:mtg_apoptosis") "Any process that stops, prevents, or reduces the frequency, rate, or extent of glial cell apoptotic process.") -AnnotationAssertion( "down regulation of glial cell apoptosis") -AnnotationAssertion( "down-regulation of glial cell apoptosis") -AnnotationAssertion( "downregulation of glial cell apoptosis") -AnnotationAssertion( "inhibition of glial cell apoptosis") -AnnotationAssertion( "negative regulation of glial cell apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0034351") -AnnotationAssertion(rdfs:label "negative regulation of glial cell apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of glial cell apoptotic process) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:mtg_apoptosis") "Any process that activates or increases the frequency, rate, or extent of glial cell apoptotic process.") -AnnotationAssertion( "up regulation of glial cell apoptosis") -AnnotationAssertion( "up-regulation of glial cell apoptosis") -AnnotationAssertion( "upregulation of glial cell apoptosis") -AnnotationAssertion( "activation of glial cell apoptosis") -AnnotationAssertion( "positive regulation of glial cell apoptosis") -AnnotationAssertion( "stimulation of glial cell apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0034352") -AnnotationAssertion(rdfs:label "positive regulation of glial cell apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (smooth muscle cell apoptotic process) - -AnnotationAssertion(Annotation( "CL:0000192") Annotation( "GOC:BHF") Annotation( "GOC:mah") Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:rl") "Any apoptotic process in a smooth muscle cell. Smooth muscle consists of non-striated, elongated, spindle-shaped cell found lining the digestive tract, uterus, and blood vessels.") -AnnotationAssertion( "SMC apoptosis") -AnnotationAssertion( "apoptosis of smooth muscle cells") -AnnotationAssertion( "programmed cell death of smooth muscle cells by apoptosis") -AnnotationAssertion( "programmed cell death, smooth muscle cells") -AnnotationAssertion( "smooth muscle cell programmed cell death by apoptosis") -AnnotationAssertion( "smooth muscle cell apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0034390") -AnnotationAssertion(rdfs:label "smooth muscle cell apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of smooth muscle cell apoptotic process) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:rl") "Any process that modulates the frequency, rate, or extent of smooth muscle cell apoptotic process.") -AnnotationAssertion( "regulation of SMC apoptosis") -AnnotationAssertion( "regulation of smooth muscle cell apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0034391") -AnnotationAssertion(rdfs:label "regulation of smooth muscle cell apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of smooth muscle cell apoptotic process) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:rl") "Any process that stops, prevents, or reduces the frequency, rate, or extent of smooth muscle cell apoptotic process.") -AnnotationAssertion( "down regulation of smooth muscle cell apoptosis") -AnnotationAssertion( "down-regulation of smooth muscle cell apoptosis") -AnnotationAssertion( "downregulation of smooth muscle cell apoptosis") -AnnotationAssertion( "negative regulation of SMC apoptosis") -AnnotationAssertion( "inhibition of smooth muscle cell apoptosis") -AnnotationAssertion( "negative regulation of smooth muscle cell apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0034392") -AnnotationAssertion(rdfs:label "negative regulation of smooth muscle cell apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of smooth muscle cell apoptotic process) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:rl") "Any process that activates or increases the frequency, rate, or extent of smooth muscle cell apoptotic process.") -AnnotationAssertion( "positive regulation of SMC apoptosis") -AnnotationAssertion( "up regulation of smooth muscle cell apoptosis") -AnnotationAssertion( "up-regulation of smooth muscle cell apoptosis") -AnnotationAssertion( "upregulation of smooth muscle cell apoptosis") -AnnotationAssertion( "activation of smooth muscle cell apoptosis") -AnnotationAssertion( "positive regulation of smooth muscle cell apoptosis") -AnnotationAssertion( "stimulation of smooth muscle cell apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0034393") -AnnotationAssertion(rdfs:label "positive regulation of smooth muscle cell apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (nucleobase-containing small molecule biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:mah") "The chemical reactions and pathways resulting in the formation of a nucleobase-containing small molecule: a nucleobase, a nucleoside, or a nucleotide.") -AnnotationAssertion( "nucleobase, nucleoside and nucleotide anabolism") -AnnotationAssertion( "nucleobase, nucleoside and nucleotide biosynthesis") -AnnotationAssertion( "nucleobase, nucleoside and nucleotide formation") -AnnotationAssertion( "nucleobase, nucleoside and nucleotide synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0034404") -AnnotationAssertion(rdfs:label "nucleobase-containing small molecule biosynthetic process") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (tectobulbar tract morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dsf") Annotation( "PMID:15065115") Annotation( "PMID:17507550") Annotation( "PMID:8038988") "Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the optic tectum towards target cells in the premotor reticulospinal system in the hindbrain.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0034429") -AnnotationAssertion(rdfs:label "tectobulbar tract morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (glycoprotein transport) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mah") Annotation( "GOC:rl") "The directed movement of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0034436") -AnnotationAssertion(rdfs:label "glycoprotein transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (vacuolar transmembrane transport) - -AnnotationAssertion(Annotation( "GOC:mah") "The process in which a solute is transported from one side of the vacuolar membrane to the other.") -AnnotationAssertion( "vacuolar membrane transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0034486") -AnnotationAssertion(rdfs:comment "Note that this term is not intended for use in annotating lateral movement within membranes.") -AnnotationAssertion(rdfs:label "vacuolar transmembrane transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (vacuolar amino acid transmembrane transport) - -AnnotationAssertion(Annotation( "GOC:mah") "The process in which an amino acid is transported from one side of the vacuolar membrane to the other.") -AnnotationAssertion( "vacuolar amino acid membrane transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0034487") -AnnotationAssertion(rdfs:comment "Note that this term is not intended for use in annotating lateral movement within membranes.") -AnnotationAssertion(rdfs:label "vacuolar amino acid transmembrane transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (protein localization to chromosome) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process in which a protein is transported to, or maintained at, a specific location on a chromosome.") -AnnotationAssertion(Annotation( "GOC:mah") "protein localisation to chromosome") -AnnotationAssertion( "condensin localization to chromosome") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0034502") -AnnotationAssertion(rdfs:label "protein localization to chromosome") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (protein localization to nucleus) - -AnnotationAssertion(Annotation( "GOC:ecd") "A process in which a protein transports or maintains the localization of another protein to the nucleus.") -AnnotationAssertion( "2012-11-07T15:45:54Z") -AnnotationAssertion( "GO:0044744") -AnnotationAssertion(Annotation( "GOC:mah") "protein localisation to nucleus") -AnnotationAssertion( "protein localization in cell nucleus") -AnnotationAssertion(Annotation( "GOC:mah") "protein localization in nucleus") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "protein targeting to nucleus") -AnnotationAssertion( "GO:0034504") -AnnotationAssertion(rdfs:label "protein localization to nucleus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (tooth mineralization) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "MP:0002817") Annotation( "MSH:D014074") "The process in which calcium salts are deposited into calcareous tooth structures such as dental enamel, dentin and cementum.") -AnnotationAssertion( "tooth calcification") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0034505") -AnnotationAssertion(rdfs:label "tooth mineralization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) # Class: (cellular nitrogen compound metabolic process) @@ -76809,503 +24326,6 @@ AnnotationAssertion(rdfs:label "cell SubClassOf( ) SubClassOf( ) -# Class: (nucleobase-containing compound biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:mah") "The chemical reactions and pathways resulting in the formation of nucleobases, nucleosides, nucleotides and nucleic acids.") -AnnotationAssertion( "nucleobase, nucleoside, nucleotide and nucleic acid anabolism") -AnnotationAssertion( "nucleobase, nucleoside, nucleotide and nucleic acid biosynthesis") -AnnotationAssertion( "nucleobase, nucleoside, nucleotide and nucleic acid formation") -AnnotationAssertion( "nucleobase, nucleoside, nucleotide and nucleic acid synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0034654") -AnnotationAssertion(rdfs:label "nucleobase-containing compound biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (nucleobase-containing compound catabolic process) - -AnnotationAssertion(Annotation( "GOC:mah") "The chemical reactions and pathways resulting in the breakdown of nucleobases, nucleosides, nucleotides and nucleic acids.") -AnnotationAssertion( "nucleobase, nucleoside, nucleotide and nucleic acid breakdown") -AnnotationAssertion( "nucleobase, nucleoside, nucleotide and nucleic acid catabolism") -AnnotationAssertion( "nucleobase, nucleoside, nucleotide and nucleic acid degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "nucleobase, nucleoside, nucleotide and nucleic acid catabolic process") -AnnotationAssertion( "GO:0034655") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "nucleobase-containing compound catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (nucleobase-containing small molecule catabolic process) - -AnnotationAssertion(Annotation( "GOC:mah") "The chemical reactions and pathways resulting in the breakdown of a nucleobase-containing small molecule: a nucleobase, a nucleoside, or a nucleotide.") -AnnotationAssertion( "nucleobase, nucleoside and nucleotide breakdown") -AnnotationAssertion( "nucleobase, nucleoside and nucleotide catabolism") -AnnotationAssertion( "nucleobase, nucleoside and nucleotide degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0034656") -AnnotationAssertion(rdfs:label "nucleobase-containing small molecule catabolic process") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (anterior/posterior pattern specification involved in pronephros development) - -AnnotationAssertion(Annotation( "GOC:mah") "The developmental process that results in the creation of defined areas or spaces within the pronephros along the anterior/posterior axis to which cells respond and eventually are instructed to differentiate.") -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "anterior/posterior pattern specification involved in pronephric kidney development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0034672") -AnnotationAssertion(rdfs:label "anterior/posterior pattern specification involved in pronephros development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (iron ion transmembrane transport) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "PMID:11390404") "A process in which an iron ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.") -AnnotationAssertion( "vw") -AnnotationAssertion( "2015-02-06T11:29:22Z") -AnnotationAssertion( "GO:0000040") -AnnotationAssertion( "GO:0006827") -AnnotationAssertion( "GO:0061839") -AnnotationAssertion( "GO:1903874") -AnnotationAssertion( "iron ion membrane transport") -AnnotationAssertion( "transmembrane iron transport") -AnnotationAssertion( "ferrous ion transmembrane transport") -AnnotationAssertion( "ferrous iron transmembrane transport") -AnnotationAssertion( "high affinity ferrous ion transmembrane transport") -AnnotationAssertion( "high affinity iron ion transport") -AnnotationAssertion( "high-affinity ferrous ion transmembrane transport") -AnnotationAssertion( "high-affinity iron ion transmembrane transport") -AnnotationAssertion( "high-affinity iron ion transport") -AnnotationAssertion( "iron(2+) transmembrane transport") -AnnotationAssertion( "low affinity iron ion transport") -AnnotationAssertion( "low-affinity iron ion transmembrane transport") -AnnotationAssertion( "low-affinity iron ion transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0034755") -AnnotationAssertion(rdfs:comment "Note that this term is not intended for use in annotating lateral movement within membranes.") -AnnotationAssertion(rdfs:label "iron ion transmembrane transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of iron ion transport) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the directed movement of iron ions (Fe) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2012-04-18T04:00:14Z") -AnnotationAssertion( "GO:1900390") -AnnotationAssertion( "regulation of Fe transport") -AnnotationAssertion( "regulation of iron transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of iron import") -AnnotationAssertion( "regulation of iron ion import") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0034756") -AnnotationAssertion(rdfs:label "regulation of iron ion transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of iron ion transport) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of iron ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion( "down regulation of iron ion transport") -AnnotationAssertion( "down-regulation of iron ion transport") -AnnotationAssertion( "downregulation of iron ion transport") -AnnotationAssertion( "negative regulation of iron transport") -AnnotationAssertion( "inhibition of iron ion transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0034757") -AnnotationAssertion(rdfs:label "negative regulation of iron ion transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of iron ion transport) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of the directed movement of iron ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion( "positive regulation of iron transport") -AnnotationAssertion( "up regulation of iron ion transport") -AnnotationAssertion( "up-regulation of iron ion transport") -AnnotationAssertion( "upregulation of iron ion transport") -AnnotationAssertion( "activation of iron ion transport") -AnnotationAssertion( "stimulation of iron ion transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0034758") -AnnotationAssertion(rdfs:label "positive regulation of iron ion transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of iron ion transmembrane transport) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the directed movement of iron ions (Fe) from one side of a membrane to the other by means of some agent such as a transporter or pore.") -AnnotationAssertion( "regulation of iron ion membrane transport") -AnnotationAssertion( "regulation of transmembrane Fe transport") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "regulation of transmembrane iron ion transport") -AnnotationAssertion( "regulation of transmembrane iron transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0034759") -AnnotationAssertion(rdfs:label "regulation of iron ion transmembrane transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of iron ion transmembrane transport) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of iron ions from one side of a membrane to the other by means of some agent such as a transporter or pore.") -AnnotationAssertion( "down regulation of transmembrane iron ion transport") -AnnotationAssertion( "down-regulation of transmembrane iron ion transport") -AnnotationAssertion( "downregulation of transmembrane iron ion transport") -AnnotationAssertion( "negative regulation of iron ion membrane transport") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "negative regulation of transmembrane iron ion transport") -AnnotationAssertion( "negative regulation of transmembrane iron transport") -AnnotationAssertion( "inhibition of transmembrane iron ion transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0034760") -AnnotationAssertion(rdfs:label "negative regulation of iron ion transmembrane transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of iron ion transmembrane transport) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of the directed movement of iron ions from one side of a membrane to the other by means of some agent such as a transporter or pore.") -AnnotationAssertion( "positive regulation of iron ion membrane transport") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "positive regulation of transmembrane iron ion transport") -AnnotationAssertion( "positive regulation of transmembrane iron transport") -AnnotationAssertion( "up regulation of transmembrane iron ion transport") -AnnotationAssertion( "up-regulation of transmembrane iron ion transport") -AnnotationAssertion( "upregulation of transmembrane iron ion transport") -AnnotationAssertion( "activation of transmembrane iron ion transport") -AnnotationAssertion( "stimulation of transmembrane iron ion transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0034761") -AnnotationAssertion(rdfs:label "positive regulation of iron ion transmembrane transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of transmembrane transport) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other.") -AnnotationAssertion( "regulation of membrane transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0034762") -AnnotationAssertion(rdfs:label "regulation of transmembrane transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of transmembrane transport) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other.") -AnnotationAssertion( "down regulation of transmembrane transport") -AnnotationAssertion( "down-regulation of transmembrane transport") -AnnotationAssertion( "downregulation of transmembrane transport") -AnnotationAssertion( "negative regulation of membrane transport") -AnnotationAssertion( "inhibition of transmembrane transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0034763") -AnnotationAssertion(rdfs:label "negative regulation of transmembrane transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of transmembrane transport) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other.") -AnnotationAssertion( "positive regulation of membrane transport") -AnnotationAssertion( "up regulation of transmembrane transport") -AnnotationAssertion( "up-regulation of transmembrane transport") -AnnotationAssertion( "upregulation of transmembrane transport") -AnnotationAssertion( "activation of transmembrane transport") -AnnotationAssertion( "stimulation of transmembrane transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0034764") -AnnotationAssertion(rdfs:label "positive regulation of transmembrane transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of monoatomic ion transmembrane transport) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other.") -AnnotationAssertion( "regulation of ion transmembrane transport") -AnnotationAssertion( "regulation of ion membrane transport") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "regulation of transmembrane ion transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0034765") -AnnotationAssertion(rdfs:label "regulation of monoatomic ion transmembrane transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of monoatomic ion transmembrane transport) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other.") -AnnotationAssertion( "negative regulation of ion transmembrane transport") -AnnotationAssertion( "down regulation of transmembrane ion transport") -AnnotationAssertion( "down-regulation of transmembrane ion transport") -AnnotationAssertion( "downregulation of transmembrane ion transport") -AnnotationAssertion( "negative regulation of ion membrane transport") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "negative regulation of transmembrane ion transport") -AnnotationAssertion( "inhibition of transmembrane ion transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0034766") -AnnotationAssertion(rdfs:label "negative regulation of monoatomic ion transmembrane transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of monoatomic ion transmembrane transport) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other.") -AnnotationAssertion( "positive regulation of ion transmembrane transport") -AnnotationAssertion( "positive regulation of ion membrane transport") -AnnotationAssertion( "positive regulation of transmembrane ion transport") -AnnotationAssertion( "up regulation of transmembrane ion transport") -AnnotationAssertion( "up-regulation of transmembrane ion transport") -AnnotationAssertion( "upregulation of transmembrane ion transport") -AnnotationAssertion( "activation of transmembrane ion transport") -AnnotationAssertion( "stimulation of transmembrane ion transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0034767") -AnnotationAssertion(rdfs:label "positive regulation of monoatomic ion transmembrane transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (basement membrane disassembly) - -AnnotationAssertion(Annotation( "GOC:sart") Annotation( "PMID:17301221") "The controlled breakdown of the basement membrane in the context of a normal process such as imaginal disc eversion.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-08-13T11:27:24Z") -AnnotationAssertion( "GO:0060881") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "basal lamina disassembly") -AnnotationAssertion( "GO:0034769") -AnnotationAssertion(rdfs:comment "Note that this term has no relationship to 'membrane disassembly ; GO:0030397' because the basement membrane is not a lipid bilayer.") -AnnotationAssertion(rdfs:label "basement membrane disassembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (response to histamine) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mah") Annotation( "GOC:vk") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a histamine stimulus. Histamine, the biogenic amine 2-(1H-imidazol-4-yl)ethanamine, is involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter.") -AnnotationAssertion( "response to histamine stimulus") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0034776") -AnnotationAssertion(rdfs:label "response to histamine") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (somatic stem cell population maintenance) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "ISBN:0582227089") "Any process by which an organism retains a population of somatic stem cells, undifferentiated cells in the embryo or adult which can undergo unlimited division and give rise to cell types of the body other than those of the germ-line.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035019") -AnnotationAssertion(rdfs:label "somatic stem cell population maintenance") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (male pronucleus assembly) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "PMID:11735001") "The conversion at fertilization of the inactive sperm nucleus into a male pronucleus with its chromosomes processed for the first zygotic division.") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") "male pronucleus formation") -AnnotationAssertion( "GO:0035039") -AnnotationAssertion(rdfs:label "male pronucleus assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (sperm nuclear envelope removal) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "PMID:11735001") "Removal of the sperm nuclear envelope, allowing entry of maternal factors into the sperm nucleus.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035040") -AnnotationAssertion(rdfs:label "sperm nuclear envelope removal") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (sperm plasma membrane disassembly) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "ISBN:0879694238") "The gradual disintegration of the sperm plasma membrane following insemination. This process is seen in Drosophila after entry of the entire sperm, surrounded by its plasma membrane, into the egg.") -AnnotationAssertion( "sperm plasma membrane breakdown") -AnnotationAssertion( "sperm plasma membrane catabolism") -AnnotationAssertion( "sperm plasma membrane degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035045") -AnnotationAssertion(rdfs:label "sperm plasma membrane disassembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (embryonic heart tube development) - -AnnotationAssertion(Annotation( "GOC:go_curators") "The process whose specific outcome is the progression of the embryonic heart tube over time, from its formation to the mature structure. The heart tube forms as the heart rudiment from the heart field.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035050") -AnnotationAssertion(rdfs:label "embryonic heart tube development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cardiocyte differentiation) - -AnnotationAssertion(Annotation( "GOC:bf") "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell that will form part of the cardiac organ of an individual.") -AnnotationAssertion( "cardiac cell differentiation") -AnnotationAssertion( "heart cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035051") -AnnotationAssertion(rdfs:label "cardiocyte differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (axoneme assembly) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:cilia") Annotation( "GOC:jl") Annotation( "ISBN:0815316194") "The assembly and organization of an axoneme, the bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements.") -AnnotationAssertion( "GO:0035083") -AnnotationAssertion( "GO:0035084") -AnnotationAssertion( "ciliary axoneme assembly") -AnnotationAssertion( "cilium axoneme assembly") -AnnotationAssertion( "flagellar axoneme assembly") -AnnotationAssertion( "flagellum axoneme assembly") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:mah") "axoneme biogenesis") -AnnotationAssertion(Annotation( "GOC:mah") "cilium axoneme biogenesis") -AnnotationAssertion( "GO:0035082") -AnnotationAssertion(rdfs:comment "Note that cilia and eukaryotic flagella are deemed to be equivalent.") -AnnotationAssertion(rdfs:label "axoneme assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (hemocyte migration) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:mtg_sensu") Annotation( "PMID:12885551") "The directed movement of a hemocyte within the embryo. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. In Drosophila, embryonic hemocytes originate from the head mesoderm as a cluster of cells. The cluster splits into two and one group of cells crosses the amnioserosa. Both populations then spread toward the middle of the embryo and then disperse evenly throughout the embryo.") -AnnotationAssertion( "arthropod blood cell migration") -AnnotationAssertion( "hemocyte cell migration") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035099") -AnnotationAssertion(rdfs:label "hemocyte migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - -# Class: (appendage morphogenesis) - -AnnotationAssertion(Annotation( "ISBN:0582227089") "The process in which the anatomical structures of appendages are generated and organized. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035107") -AnnotationAssertion(rdfs:label "appendage morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (limb morphogenesis) - -AnnotationAssertion(Annotation( "UBERON:0002101") "The process in which the anatomical structures of a limb are generated and organized. A limb is a paired appendage of a tetrapod used for locomotion or grasping.") -AnnotationAssertion(Annotation( "GOC:dph") "limb bud morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035108") -AnnotationAssertion(rdfs:label "limb morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (genitalia morphogenesis) - -AnnotationAssertion(Annotation( "GOC:bf") "The process in which the anatomical structures of genitalia are generated and organized. The genitalia are the organs of reproduction or generation, external and internal.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "genital morphogenesis") -AnnotationAssertion( "GO:0035112") -AnnotationAssertion(rdfs:label "genitalia morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (imaginal disc-derived appendage morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_sensu") Annotation( "ISBN:0582227089") "The process in which the anatomical structures of appendages are generated and organized. An appendage is an organ or part that is attached to the trunk of an organism.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035114") -AnnotationAssertion(rdfs:label "imaginal disc-derived appendage morphogenesis") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (post-embryonic appendage morphogenesis) - -AnnotationAssertion(Annotation( "ISBN:0582227089") "The process, occurring after embryonic development, by which the anatomical structures of an appendage are generated and organized. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035120") -AnnotationAssertion(rdfs:label "post-embryonic appendage morphogenesis") -SubClassOf( ) -SubClassOf( ) - -# Class: (forelimb morphogenesis) - -AnnotationAssertion(Annotation( "GOC:go_curators") "The process in which the anatomical structures of the forelimb are generated and organized. The forelimbs are the front limbs of an animal, e.g. the arms of a human.") -AnnotationAssertion( "GO:0035140") -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:cjm") "arm morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035136") -AnnotationAssertion(rdfs:label "forelimb morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (hindlimb morphogenesis) - -AnnotationAssertion(Annotation( "GOC:go_curators") "The process in which the anatomical structures of the hindlimb are generated and organized.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035137") -AnnotationAssertion(rdfs:label "hindlimb morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (pectoral fin morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dgh") "The process in which the anatomical structures of the pectoral fin are generated and organized. Pectoral fins are bilaterally paired fins mounted laterally and located behind the gill covers of fish. These fins are used for lateral mobility and propulsion.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035138") -AnnotationAssertion(rdfs:label "pectoral fin morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (pelvic fin morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dgh") "The process in which the anatomical structures of the pelvic fin are generated and organized. Pelvic fins are bilaterally paired fins mounted in a ventral-lateral position on most fish. These fins are used primarily for lateral mobility and propulsion.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035139") -AnnotationAssertion(rdfs:label "pelvic fin morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (medial fin morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dgh") "The process in which the anatomical structures of the medial fin are generated and organized. A medial fin is an unpaired fin of fish, usually located dorsomedially or ventromedially and primarily used for stability while swimming.") -AnnotationAssertion( "median fin morphogenesis") -AnnotationAssertion( "unpaired fin morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035141") -AnnotationAssertion(rdfs:label "medial fin morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (dorsal fin morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dgh") "The process in which the anatomical structures of the dorsal fin are generated and organized. A dorsal fin is an unpaired medial fin on the dorsal aspect of fish that provides lateral stability while swimming. Generally fish have one or two dorsal fins.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035142") -AnnotationAssertion(rdfs:label "dorsal fin morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (caudal fin morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dgh") "The process in which the anatomical structures of the caudal fin are generated and organized. A caudal fin is an unpaired medial fin mounted at the caudal end of the fish, and is the main fin used for propulsion.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035143") -AnnotationAssertion(rdfs:label "caudal fin morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (anal fin morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dgh") "The process in which the anatomical structures of the anal fin are generated and organized. An anal fin is an unpaired medial fin on the ventral aspect near the caudal end of a fish, which provides lateral stability while swimming.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035144") -AnnotationAssertion(rdfs:label "anal fin morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (tube formation) AnnotationAssertion(Annotation( "GOC:bf") "Creation of the central hole of a tube in an anatomical structure through which gases and/or liquids flow.") @@ -77314,36 +24334,10 @@ AnnotationAssertion( "GOC:dph") Annotation( "GOC:mah") "lumen formation in an anatomical structure") AnnotationAssertion( "GO:0035148") AnnotationAssertion(rdfs:label "tube formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (embryonic hemopoiesis) - -AnnotationAssertion(Annotation( "GOC:bf") "The stages of blood cell formation that take place within the embryo.") -AnnotationAssertion( "embryonic haematopoiesis") -AnnotationAssertion( "embryonic haemopoiesis") -AnnotationAssertion( "embryonic hematopoiesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035162") -AnnotationAssertion(rdfs:label "embryonic hemopoiesis") -SubClassOf( ) -SubClassOf( ) - -# Class: (hemocyte proliferation) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:mtg_sensu") "The multiplication or reproduction of hemocytes, resulting in the expansion of the cell population. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen.") -AnnotationAssertion( "arthropod blood cell proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035172") -AnnotationAssertion(rdfs:label "hemocyte proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - # Class: (hatching) AnnotationAssertion(Annotation( "GOC:dgh") Annotation( "GOC:isa_complete") Annotation( "ISBN:0198612001") "The emergence of an immature organism from a protective structure.") @@ -77353,140 +24347,26 @@ AnnotationAssertion(rdfs:label "hatc SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (syncytial nuclear migration) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "ISBN:0879694238") Annotation( "PMID:8314839") "The directed movement of nuclei within the syncytial embryo of insects. These precise temporal and spatial patterns of nuclear movement are coordinated with mitotic divisons and are required during blastoderm formation to reposition dividing nuclei from the interior of the syncytial embryo to the cortex.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035190") -AnnotationAssertion(rdfs:label "syncytial nuclear migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (regulation of hemocyte proliferation) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:mtg_sensu") "Any process that modulates the frequency, rate or extent of hemocyte proliferation. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. An example of this is found in Drosophila melanogaster.") -AnnotationAssertion( "regulation of arthropod blood cell proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035206") -AnnotationAssertion(rdfs:label "regulation of hemocyte proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of hemocyte proliferation) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:mtg_sensu") "Any process that stops, prevents or reduces the rate or extent of hemocyte proliferation. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. An example of this is found in Drosophila melanogaster.") -AnnotationAssertion( "down regulation of hemocyte proliferation") -AnnotationAssertion( "down-regulation of hemocyte proliferation") -AnnotationAssertion( "downregulation of hemocyte proliferation") -AnnotationAssertion( "negative regulation of arthropod blood cell proliferation") -AnnotationAssertion( "inhibition of hemocyte proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035207") -AnnotationAssertion(rdfs:label "negative regulation of hemocyte proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - -# Class: (positive regulation of hemocyte proliferation) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:mtg_sensu") "Any process that activates or increases the rate or extent of hemocyte proliferation. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) that are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. An example of this process is found in Drosophila melanogaster.") -AnnotationAssertion( "positive regulation of arthropod blood cell proliferation") -AnnotationAssertion( "up regulation of hemocyte proliferation") -AnnotationAssertion( "up-regulation of hemocyte proliferation") -AnnotationAssertion( "upregulation of hemocyte proliferation") -AnnotationAssertion( "activation of hemocyte proliferation") -AnnotationAssertion( "stimulation of hemocyte proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035208") -AnnotationAssertion(rdfs:label "positive regulation of hemocyte proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (pupal development) AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:mtg_sensu") "The process whose specific outcome is the progression of the pupa over time, from its formation to the mature structure. The pupa is a dormant life stage interposed between the larval and the adult stages in insects that undergo a complete metamorphosis.") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0035209") AnnotationAssertion(rdfs:label "pupal development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (spermathecum morphogenesis) - -AnnotationAssertion(Annotation( "PMID:12679097") "The process in which the anatomical structures of a spermathecum, a sperm storage organ, are generated and organized. Paired spermathecae lie at the anterior end of the insect uterus on the dorsal side. Each spermatheca consists of an oval shaped capsule, connected to the uterus by a spermathecal stalk.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035211") -AnnotationAssertion(rdfs:comment "See also the fly_anatomy.ontology term 'spermathecum ; FBbt:00004921'.") -AnnotationAssertion(rdfs:label "spermathecum morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (eye-antennal disc development) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "ISBN:0879694238") "Progression of the eye-antennal imaginal disc over time, from its initial formation through to its metamorphosis to form adult structures including the eye, antenna, head capsule and maxillary palps.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035214") -AnnotationAssertion(rdfs:label "eye-antennal disc development") -SubClassOf( ) - -# Class: (haltere disc development) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "ISBN:0879694238") "Progression of the haltere imaginal disc over time, from its initial formation through to its metamorphosis to form the adult capitellum, pedicel, haltere sclerite, metathoracic spiracle and metanotum.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035216") -AnnotationAssertion(rdfs:label "haltere disc development") -SubClassOf( ) - -# Class: (leg disc development) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "ISBN:0879694238") "Progression of the leg imaginal disc over time, from its initial formation through to its metamorphosis to form adult structures including the leg, coxa and ventral thoracic pleura.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035218") -AnnotationAssertion(rdfs:label "leg disc development") -SubClassOf( ) - -# Class: (wing disc development) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "ISBN:0879694238") "Progression of the wing disc over time, from its initial formation through to its metamorphosis to form adult structures including the wing hinge, wing blade and pleura.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035220") -AnnotationAssertion(rdfs:label "wing disc development") -SubClassOf( ) - -# Class: (ectopic germ cell programmed cell death) - -AnnotationAssertion(Annotation( "PMID:12814944") "Programmed cell death of an errant germ line cell that is outside the normal migratory path or ectopic to the gonad. This is an important mechanism of regulating germ cell survival within the embryo.") -AnnotationAssertion( "programmed cell death of ectopic germ cells") -AnnotationAssertion( "programmed cell death, ectopic germ cells") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035234") -AnnotationAssertion(rdfs:label "ectopic germ cell programmed cell death") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - # Class: (tube morphogenesis) AnnotationAssertion(Annotation( "GOC:bf") Annotation( "PMID:14624839") "The process in which the anatomical structures of a tube are generated and organized. Epithelial and endothelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues, with tube shape and organization varying from the single-celled excretory organ in Caenorhabditis elegans to the branching trees of the mammalian kidney and insect tracheal system.") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0035239") AnnotationAssertion(rdfs:label "tube morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (dopamine binding) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "Binding to dopamine, a catecholamine neurotransmitter formed by aromatic-L-amino-acid decarboxylase from 3,4-dihydroxy-L-phenylalanine.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0035240") -AnnotationAssertion(rdfs:label "dopamine binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (synaptic transmission, glutamatergic) AnnotationAssertion(Annotation( "GOC:dos") "The vesicular release of glutamate from a presynapse, across a chemical synapse, the subsequent activation of glutamate receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.") @@ -77496,576 +24376,15 @@ AnnotationAssertion( "synaptic transmission, glutamatergic") SubClassOf( ) -# Class: (internal genitalia morphogenesis) - -AnnotationAssertion(Annotation( "http://www.ndif.org/Terms/genitalia.html") "The process in which the anatomical structures of the internal genitalia are generated and organized. The internal genitalia are the internal sex organs such as the uterine tube, the uterus and the vagina in female mammals, and the testis, seminal vesicle, ejaculatory duct and prostate in male mammals.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035260") -AnnotationAssertion(rdfs:label "internal genitalia morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (external genitalia morphogenesis) - -AnnotationAssertion(Annotation( "http://www.ndif.org/Terms/genitalia.html") "The process in which the anatomical structures of the external genitalia are generated and organized. The external genitalia are the outer sex organs, such as the penis or vulva in mammals.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035261") -AnnotationAssertion(rdfs:label "external genitalia morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (gonad morphogenesis) - -AnnotationAssertion(Annotation( "ISBN:0198612001") "The process in which the anatomical structures of the gonads are generated and organized. A gonad is an animal organ producing gametes, e.g. the testes or the ovary in mammals.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035262") -AnnotationAssertion(rdfs:label "gonad morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (multicellular organism growth) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:curators") Annotation( "GOC:dph") Annotation( "GOC:tb") "The increase in size or mass of an entire multicellular organism, as opposed to cell growth.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "body growth") -AnnotationAssertion( "GO:0035264") -AnnotationAssertion(rdfs:label "multicellular organism growth") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (organ growth) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "ISBN:0471245208") Annotation( "ISBN:0721662544") "The increase in size or mass of an organ. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that function together as to perform a specific function.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035265") -AnnotationAssertion(rdfs:label "organ growth") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (endocrine system development) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "Wikipedia:Development_of_the_endocrine_system") "Progression of the endocrine system over time, from its formation to a mature structure. The endocrine system is a system of hormones and ductless glands, where the glands release hormones directly into the blood, lymph or other intercellular fluid, and the hormones circulate within the body to affect distant organs. The major glands that make up the human endocrine system are the hypothalamus, pituitary, thyroid, parathryoids, adrenals, pineal body, and the reproductive glands which include the ovaries and testes.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035270") -AnnotationAssertion(rdfs:label "endocrine system development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (exocrine system development) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "Wikipedia:Exocrine_gland") "Progression of the exocrine system over time, from its formation to a mature structure. The exocrine system is a system of hormones and glands, where the glands secrete straight to a target site via ducts or tubes. The human exocrine system includes the salivary glands, sweat glands and many glands of the digestive system.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035272") -AnnotationAssertion(rdfs:label "exocrine system development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (segmentation) - -AnnotationAssertion(Annotation( "PMID:10611687") Annotation( "PMID:9706689") "The regionalization process that divides an organism or part of an organism into a series of semi-repetitive parts, or segments, often arranged along a longitudinal axis.") -AnnotationAssertion( "Wikipedia:Segmentation_(biology)") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035282") -AnnotationAssertion(rdfs:label "segmentation") -SubClassOf( ) - -# Class: (trunk segmentation) - -AnnotationAssertion(Annotation( "PMID:1360402") "Partitioning of the blastoderm embryo into trunk segmental units. In Drosophila, the trunk segments include thoracic segments and abdominal segments A1 to A8.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035290") -AnnotationAssertion(rdfs:label "trunk segmentation") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (tube development) AnnotationAssertion(Annotation( "PMID:12526790") "The process whose specific outcome is the progression of a tube over time, from its initial formation to a mature structure. Epithelial and endothelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues including lung and trachea, kidney, the mammary gland, the vascular system and the gastrointestinal and urinary-genital tracts.") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0035295") AnnotationAssertion(rdfs:label "tube development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (hair cell differentiation) - -AnnotationAssertion(Annotation( "GOC:bf") "The process in which a relatively unspecialized cell acquires specialized features of a hair cell.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035315") -AnnotationAssertion(rdfs:label "hair cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (non-sensory hair organization) - -AnnotationAssertion(Annotation( "GOC:mtg_sensu") Annotation( "PMID:11064425") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of non-sensory hairs. These hairs are polarized cellular extensions that cover much of the insect epidermis.") -AnnotationAssertion( "trichome organisation") -AnnotationAssertion( "trichome organization and biogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:mah") "non-sensory hair organization and biogenesis") -AnnotationAssertion( "GO:0035316") -AnnotationAssertion(rdfs:comment "See also the fly_anatomy.ontology term 'trichome ; FBbt:00004979'.") -AnnotationAssertion(rdfs:label "non-sensory hair organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - -# Class: (imaginal disc-derived wing hair organization) - -AnnotationAssertion(Annotation( "GOC:mtg_sensu") Annotation( "PMID:11064425") Annotation( "PMID:12540853") "A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of an imaginal disc-derived wing hair. A wing hair is an actin-rich, polarized, non-sensory apical projection that protrudes from each of the approximately 30,000 wing epithelial cells. An example of this is found in Drosophila melanogaster.") -AnnotationAssertion( "wing hair organisation") -AnnotationAssertion( "wing trichome organization and biogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:mah") "imaginal disc-derived wing hair organization and biogenesis") -AnnotationAssertion(Annotation( "GOC:mah") "wing hair organization and biogenesis") -AnnotationAssertion( "GO:0035317") -AnnotationAssertion(rdfs:comment "See also the fly_anatomy.ontology term 'wing hair ; FBbt:00004340'.") -AnnotationAssertion(rdfs:label "imaginal disc-derived wing hair organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (mesenchymal cell migration involved in limb bud formation) - -AnnotationAssertion(Annotation( "GOC:dgh") "The orderly movement of a mesenchymal cell from one site to another that will contribute to the formation of a limb bud.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2010-02-24T02:05:14Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035322") -AnnotationAssertion(rdfs:label "mesenchymal cell migration involved in limb bud formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (pre-B cell receptor complex) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781765196") Annotation( "PMID:16464608") Annotation( "PMID:17306522") "An immunoglobulin-like complex that is present in at least the plasma membrane of pre-B cells, and that is composed of two identical immunoglobulin heavy chains and two surrogate light chains, each composed of the lambda-5 and VpreB proteins, and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2010-03-11T10:46:10Z") -AnnotationAssertion( "pre-BCR") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0035369") -AnnotationAssertion(rdfs:comment "Despite its name, the pre-BCR is not a receptor complex, as it appears to provide a low level of signal not dependent on a ligand, but rather simply on correct assembly of the complex as a measure for correct Ig heavy chain recombination and folding. A significant proportion of pre-BCR complexes fail to reach the cell surface, and in some cases may provide their signaling function from the trans-Golgi network or lysosome.") -AnnotationAssertion(rdfs:label "pre-B cell receptor complex") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (protein localization to microtubule) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:lb") "A process in which a protein is transported to, or maintained at, a microtubule.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2010-03-11T11:00:56Z") -AnnotationAssertion(Annotation( "GOC:mah") "protein localisation to microtubule") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035372") -AnnotationAssertion(rdfs:label "protein localization to microtubule") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (chondroitin sulfate binding) - -AnnotationAssertion(Annotation( "GOC:kmv") Annotation( "ISBN:0198506732") "Binding to chondroitin sulfate, a glycosaminoglycan made up of two alternating monosaccharides: D-glucuronic acid (GlcA) and N-acetyl-D-galactosamine (GalNAc).") -AnnotationAssertion( "bf") -AnnotationAssertion( "2010-03-12T10:25:34Z") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0035374") -AnnotationAssertion(rdfs:label "chondroitin sulfate binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (transepithelial water transport) - -AnnotationAssertion(Annotation( "GOC:yaf") "The directed movement of water (H2O) from one side of an epithelium to the other.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2010-03-18T10:55:38Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035377") -AnnotationAssertion(rdfs:label "transepithelial water transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (carbon dioxide transmembrane transport) - -AnnotationAssertion(Annotation( "GOC:yaf") "The process in which carbon dioxide (CO2) is transported across a membrane.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2010-03-18T11:17:54Z") -AnnotationAssertion( "carbon dioxide membrane transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035378") -AnnotationAssertion(rdfs:comment "Note that this term is not intended for use in annotating lateral movement within membranes.") -AnnotationAssertion(rdfs:label "carbon dioxide transmembrane transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (carbon dioxide transmembrane transporter activity) - -AnnotationAssertion(Annotation( "GOC:yaf") "Enables the transfer of carbon dioxide (CO2) from one side of a membrane to the other.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2010-03-18T11:19:38Z") -AnnotationAssertion(Annotation(rdfs:label "AQP1 tetramer transports CO2 from extracellular region to cytosol") "Reactome:R-HSA-1237042") -AnnotationAssertion(Annotation(rdfs:label "RHAG transports CO2 from extracellular region to cytosol") "Reactome:R-HSA-1237069") -AnnotationAssertion(Annotation(rdfs:label "RHAG transports CO2 from cytosol to extracellular region") "Reactome:R-HSA-1247645") -AnnotationAssertion(Annotation(rdfs:label "AQP1 tetramer transports CO2 from cytosol to extracellular region") "Reactome:R-HSA-1247649") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0035379") -AnnotationAssertion(rdfs:label "carbon dioxide transmembrane transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "GO_REF:0000090") ObjectSomeValuesFrom( )) - -# Class: (protein localization to synapse) - -AnnotationAssertion(Annotation( "GOC:bf") "Any process in which a protein is transported to, and/or maintained at the synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2010-03-29T10:58:53Z") -AnnotationAssertion(Annotation( "GOC:mah") "protein localisation to synapse") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035418") -AnnotationAssertion(rdfs:label "protein localization to synapse") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (acetate transmembrane transport) - -AnnotationAssertion(Annotation( "GOC:vw") "The process in which acetate is transported across a membrane. Acetate is the 2-carbon carboxylic acid ethanoic acid.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2010-04-08T10:59:01Z") -AnnotationAssertion( "acetate membrane transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035433") -AnnotationAssertion(rdfs:comment "Note that this term is not intended for use in annotating lateral movement within membranes.") -AnnotationAssertion(rdfs:label "acetate transmembrane transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (phosphate ion transmembrane transport) - -AnnotationAssertion(Annotation( "GOC:vw") "The process in which a phosphate is transported across a membrane.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2010-04-08T11:24:06Z") -AnnotationAssertion( "phosphate ion membrane transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035435") -AnnotationAssertion(rdfs:comment "Note that this term is not intended for use in annotating lateral movement within membranes.") -AnnotationAssertion(rdfs:label "phosphate ion transmembrane transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (cell migration involved in vasculogenesis) - -AnnotationAssertion(Annotation( "GOC:dgh") "The orderly movement of a cell from one site to another that will contribute to the differentiation of an endothelial cell that will form de novo blood vessels and tubes.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2010-04-09T03:53:01Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035441") -AnnotationAssertion(rdfs:label "cell migration involved in vasculogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (intracellular signal transduction) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:jl") Annotation( "GOC:signaling") Annotation( "ISBN:3527303782") "The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2010-05-14T01:14:37Z") -AnnotationAssertion( "GO:0007242") -AnnotationAssertion( "GO:0007243") -AnnotationAssertion( "GO:0023013") -AnnotationAssertion( "GO:0023034") -AnnotationAssertion(Annotation( "ISBN:3527303782") "intracellular signaling chain") -AnnotationAssertion(Annotation( "GOC:signaling") "intracellular protein kinase cascade") -AnnotationAssertion( "intracellular signal transduction pathway") -AnnotationAssertion(Annotation( "GOC:signaling") "protein kinase cascade") -AnnotationAssertion( "signal transmission via intracellular cascade") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:signaling") "intracellular signaling cascade") -AnnotationAssertion( "intracellular signaling pathway") -AnnotationAssertion( "signal transduction via intracellular signaling cascade") -AnnotationAssertion( "GO:0035556") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "intracellular signal transduction") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of chromatin binding) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "PMID:20404130") "Any process that modulates the frequency, rate or extent of chromatin binding. Chromatin binding is the selective interaction with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2010-05-19T10:28:36Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035561") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "regulation of chromatin binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of chromatin binding) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "PMID:20404130") "Any process that stops or reduces the frequency, rate or extent of chromatin binding. Chromatin binding is the selective interaction with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2010-05-19T10:29:06Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035562") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "negative regulation of chromatin binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of chromatin binding) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "PMID:20404130") "Any process that increases the frequency, rate or extent of chromatin binding. Chromatin binding is the selective interaction with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2010-05-19T10:29:41Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035563") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "positive regulation of chromatin binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (azurophil granule membrane) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "PMID:17152095") "The lipid bilayer surrounding an azurophil granule, a primary lysosomal granule found in neutrophil granulocytes that contains a wide range of hydrolytic enzymes and is released into the extracellular fluid.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2010-10-05T01:29:10Z") -AnnotationAssertion( "primary granule membrane") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0035577") -AnnotationAssertion(rdfs:label "azurophil granule membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (G protein-coupled purinergic receptor signaling pathway) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "PMID:9755289") "A G protein-coupled receptor signaling pathway initiated by an extracellular purine or purine derivative binding to its receptor, and ending with the regulation of a downstream cellular process.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2010-10-22T11:11:53Z") -AnnotationAssertion( "G-protein coupled purinergic receptor signaling pathway") -AnnotationAssertion(Annotation( "GOC:mah") "G-protein coupled purinergic receptor signalling pathway") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035588") -AnnotationAssertion(rdfs:label "G protein-coupled purinergic receptor signaling pathway") -SubClassOf( ) -SubClassOf( ) - -# Class: (G protein-coupled purinergic nucleotide receptor signaling pathway) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "PMID:9755289") "A G protein-coupled receptor signaling pathway initiated by an extracellular purine nucleotide binding to its receptor, and ending with the regulation of a downstream cellular process.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2010-10-22T11:18:59Z") -AnnotationAssertion( "G-protein coupled purinergic nucleotide receptor signaling pathway") -AnnotationAssertion(Annotation( "GOC:mah") "G-protein coupled purinergic nucleotide receptor signalling pathway") -AnnotationAssertion(Annotation( "PMID:9755289") "P2Y receptor signaling pathway") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035589") -AnnotationAssertion(rdfs:label "G protein-coupled purinergic nucleotide receptor signaling pathway") -SubClassOf( ) - -# Class: (purinergic nucleotide receptor signaling pathway) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "PMID:9755289") "The series of molecular signals initiated by an extracellular purine nucleotide binding to its receptor, and ending with the regulation of a downstream cellular process, e.g. transcription.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2010-10-22T11:09:40Z") -AnnotationAssertion( "GO:0035587") -AnnotationAssertion(Annotation( "GOC:mah") "purinergic nucleotide receptor signalling pathway") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "PMID:9755289") "P2 receptor signaling pathway") -AnnotationAssertion( "purinergic receptor signaling pathway") -AnnotationAssertion(Annotation( "GOC:mah") "purinergic receptor signalling pathway") -AnnotationAssertion(Annotation( "PMID:9755289") "purinoceptor signaling pathway") -AnnotationAssertion( "GO:0035590") -AnnotationAssertion(rdfs:label "purinergic nucleotide receptor signaling pathway") -SubClassOf( ) - -# Class: (establishment of protein localization to extracellular region) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:bf") "The directed movement of a protein to a specific location within the extracellular region.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2010-11-09T10:25:08Z") -AnnotationAssertion(Annotation( "GOC:mah") "establishment of protein localisation in extracellular region") -AnnotationAssertion( "establishment of protein localization in extracellular region") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035592") -AnnotationAssertion(rdfs:label "establishment of protein localization to extracellular region") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (intrahepatic bile duct development) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "PMID:20614624") "The progression of the intrahepatic bile ducts over time, from their formation to the mature structure. Intrahepatic bile ducts (bile ducts within the liver) collect bile from bile canaliculi in the liver, and connect to the extrahepatic bile ducts (bile ducts outside the liver).") -AnnotationAssertion( "bf") -AnnotationAssertion( "2010-12-08T04:10:50Z") -AnnotationAssertion(Annotation( "PMID:20614624") "IHBD development") -AnnotationAssertion(Annotation( "PMID:20614624") "intrahepatic biliary duct development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035622") -AnnotationAssertion(rdfs:label "intrahepatic bile duct development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (ceramide transport) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:sart") "The directed movement of ceramides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Ceramides are a class of lipid composed of sphingosine linked to a fatty acid.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2010-12-10T10:02:16Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035627") -AnnotationAssertion(rdfs:label "ceramide transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cystic duct development) - -AnnotationAssertion(Annotation( "PMID:20614624") "The progression of the cystic duct over time, from its formation to the mature structure. The cystic duct runs from the gallbladder to the common bile duct.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2010-12-10T01:24:28Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035628") -AnnotationAssertion(rdfs:label "cystic duct development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (bone mineralization involved in bone maturation) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:bf") "The deposition of hydroxyapatite, involved in the progression of the skeleton from its formation to its mature state.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2010-12-20T01:57:31Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035630") -AnnotationAssertion(rdfs:comment "Bone mineralization can also occur after a fracture and as a response to stress; in these cases, consider using the term 'bone mineralization ; GO:0030282'.") -AnnotationAssertion(rdfs:label "bone mineralization involved in bone maturation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (purine ribonucleoside triphosphate binding) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:ebc") Annotation( "ISBN:0198506732") "Binding to a purine ribonucleoside triphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with triphosphate on the sugar.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-01-14T02:46:42Z") -AnnotationAssertion(Annotation( "GOC:ebc") "purine NTP binding") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0035639") -AnnotationAssertion(rdfs:label "purine ribonucleoside triphosphate binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (enteric smooth muscle cell differentiation) - -AnnotationAssertion(Annotation( "CL:0002504") Annotation( "GOC:BHF") "The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell of the intestine.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-01-21T02:58:58Z") -AnnotationAssertion(Annotation( "CL:0002504") "intestinal smooth muscle cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035645") -AnnotationAssertion(rdfs:label "enteric smooth muscle cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (neuromast hair cell development) - -AnnotationAssertion(Annotation( "CL:0000856") "The process whose specific outcome is the progression of a neuromast hair cell over time, from its formation to the mature structure. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. Cell development does not include the steps involved in committing a cell to a specific fate.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-02-14T11:01:42Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035675") -AnnotationAssertion(rdfs:label "neuromast hair cell development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (anterior lateral line neuromast hair cell development) - -AnnotationAssertion(Annotation( "ISBN:0125296509") Annotation( "ISBN:0387968377") "The process whose specific outcome is the progression of an anterior lateral line neuromast hair cell over time, from its formation to the mature structure. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. Cell development does not include the steps involved in committing a cell to a specific fate.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-02-14T11:03:57Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035676") -AnnotationAssertion(rdfs:label "anterior lateral line neuromast hair cell development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (posterior lateral line neuromast hair cell development) - -AnnotationAssertion(Annotation( "ISBN:0125296509") "The process whose specific outcome is the progression of a posterior lateral line neuromast hair cell over time, from its formation to the mature structure. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. Cell development does not include the steps involved in committing a cell to a specific fate.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-02-14T11:04:57Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035677") -AnnotationAssertion(rdfs:label "posterior lateral line neuromast hair cell development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (neuromast hair cell morphogenesis) - -AnnotationAssertion(Annotation( "CL:0000856") "The change in form (cell shape and size) that occurs when a neuromast hair cell progresses from its initial formation to its mature state. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-02-14T11:06:15Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035678") -AnnotationAssertion(rdfs:label "neuromast hair cell morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (astrocyte chemotaxis) - -AnnotationAssertion(Annotation( "CL:0000127") Annotation( "GOC:BHF") Annotation( "PMID:12271471") "The directed movement of an astrocyte guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-02-28T03:17:52Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035700") -AnnotationAssertion(rdfs:label "astrocyte chemotaxis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (hematopoietic stem cell migration) - -AnnotationAssertion(Annotation( "CL:0000037") Annotation( "GOC:BHF") Annotation( "PMID:20234092") "The orderly movement of a hematopoietic stem cell from one site to another. A hematopoietic stem cell is a cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-02-28T03:20:36Z") -AnnotationAssertion(Annotation( "CL:0000037") "hemopoietic stem cell migration") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035701") -AnnotationAssertion(rdfs:label "hematopoietic stem cell migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (monocyte homeostasis) - -AnnotationAssertion(Annotation( "CL:0000576") Annotation( "GOC:BHF") Annotation( "PMID:18832716") "The process of regulating the proliferation and elimination of monocytes such that the total number of monocytes within a whole or part of an organism is stable over time in the absence of an outside stimulus.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-03-02T11:32:57Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035702") -AnnotationAssertion(rdfs:label "monocyte homeostasis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (sodium ion transmembrane transport) - -AnnotationAssertion(Annotation( "GOC:vw") "A process in which a sodium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-03-10T02:52:36Z") -AnnotationAssertion( "sodium ion membrane transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035725") -AnnotationAssertion(rdfs:comment "Note that this term is not intended for use in annotating lateral movement within membranes.") -AnnotationAssertion(rdfs:label "sodium ion transmembrane transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (hepatic stellate cell activation) - -AnnotationAssertion(Annotation( "CL:0000632") Annotation( "GOC:bf") "A change in the morphology or behavior of a hepatic stellate cell resulting from exposure to a cytokine, chemokine, hormone, cellular ligand or soluble factor.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-03-11T10:04:12Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035733") -AnnotationAssertion(rdfs:label "hepatic stellate cell activation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - # Class: (intraciliary transport involved in cilium assembly) AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:cilia") Annotation( "Reactome:R-HSA-5620924.2") "The bidirectional movement of large protein complexes along microtubules within a cilium that contributes to cilium assembly.") @@ -78078,260 +24397,6 @@ AnnotationAssertion( "intraflagellar transport involved in cilium morphogenesis") AnnotationAssertion( "GO:0035735") AnnotationAssertion(rdfs:label "intraciliary transport involved in cilium assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cell proliferation involved in compound eye morphogenesis) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:sart") "The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to compound eye morphogenesis.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-03-17T10:57:03Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035736") -AnnotationAssertion(rdfs:label "cell proliferation involved in compound eye morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (B cell chemotaxis) - -AnnotationAssertion(Annotation( "CL:0000236") Annotation( "GOC:BHF") "The directed movement of a B cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-03-23T10:30:33Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035754") -AnnotationAssertion(rdfs:label "B cell chemotaxis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (dorsal motor nucleus of vagus nerve maturation) - -AnnotationAssertion(Annotation( "GOC:dgh") "A developmental process, independent of morphogenetic (shape) change, that is required for the dorsal motor nucleus of the vagus nerve to attain its fully functional state.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-03-29T02:45:50Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035761") -AnnotationAssertion(rdfs:label "dorsal motor nucleus of vagus nerve maturation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (dorsal motor nucleus of vagus nerve morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dgh") "The process in which the dorsal motor nucleus of the vagus nerve is generated and organized. Morphogenesis pertains to the creation of form.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-03-29T02:47:18Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035762") -AnnotationAssertion(rdfs:label "dorsal motor nucleus of vagus nerve morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (dorsal motor nucleus of vagus nerve formation) - -AnnotationAssertion(Annotation( "GOC:dgh") "The process that gives rise to the dorsal motor nucleus of the vagus nerve. This process pertains to the initial formation of a structure from unspecified parts.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-03-29T02:48:26Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035764") -AnnotationAssertion(rdfs:label "dorsal motor nucleus of vagus nerve formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (motor neuron precursor migration involved in dorsal motor nucleus of vagus nerve formation) - -AnnotationAssertion(Annotation( "GOC:dgh") Annotation( "PMID:21262462") "The orderly movement of a motor neuron precursor cell that contributes to formation of the dorsal motor nucleus of the vagus nerve.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-03-29T02:52:09Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035765") -AnnotationAssertion(rdfs:label "motor neuron precursor migration involved in dorsal motor nucleus of vagus nerve formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (endothelial cell chemotaxis) - -AnnotationAssertion(Annotation( "CL:0000115") Annotation( "GOC:BHF") "The directed movement of an endothelial cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-03-31T04:31:37Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035767") -AnnotationAssertion(rdfs:label "endothelial cell chemotaxis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (insulin secretion involved in cellular response to glucose stimulus) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:yaf") Annotation( "PMID:8492079") "The regulated release of proinsulin from secretory granules (B granules) in the B cells of the pancreas; accompanied by cleavage of proinsulin to form mature insulin, in response to a glucose stimulus.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-04-01T01:14:40Z") -AnnotationAssertion(Annotation( "GOC:bf") "insulin secretion involved in cellular response to glucose") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035773") -AnnotationAssertion(rdfs:label "insulin secretion involved in cellular response to glucose stimulus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of insulin secretion involved in cellular response to glucose stimulus) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:yaf") "Any process that increases the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-04-01T01:49:09Z") -AnnotationAssertion(Annotation( "GOC:bf") "positive regulation of insulin secretion in response to glucose") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035774") -AnnotationAssertion(rdfs:label "positive regulation of insulin secretion involved in cellular response to glucose stimulus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (pronephric glomerulus morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") Annotation( "GOC:yaf") Annotation( "PMID:18787069") "The process in which the anatomical structures of the pronephric glomerulus are generated and organized. The pronephric glomerulus is part of the pronephric nephron and is restricted to one body segment.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-04-04T10:59:28Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035775") -AnnotationAssertion(rdfs:comment "This term is intended for annotation of fish and other organisms which contain a glomerulus as part of the pronephric nephron. It should not be used for annotation of Xenopus, which contains a pronephric glomus rather than a glomerulus.") -AnnotationAssertion(rdfs:label "pronephric glomerulus morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (pronephric proximal tubule development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") Annotation( "GOC:yaf") Annotation( "PMID:18787069") "The progression of the pronephric proximal tubule over time, from its formation to the mature structure. A pronephric nephron tubule is an epithelial tube that is part of the pronephros.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-04-04T11:02:54Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035776") -AnnotationAssertion(rdfs:label "pronephric proximal tubule development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (pronephric distal tubule development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") Annotation( "GOC:yaf") Annotation( "PMID:18787069") "The process whose specific outcome is the progression of the pronephric distal tubule over time, from its formation to the mature structure. A pronephric nephron tubule is an epithelial tube that is part of the pronephros.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-04-04T11:06:01Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035777") -AnnotationAssertion(rdfs:label "pronephric distal tubule development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (pronephric nephron tubule epithelial cell differentiation) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") Annotation( "GOC:yaf") Annotation( "PMID:18787069") "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the pronephric nephron tubule as it progresses from its formation to the mature state.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-04-04T11:07:47Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035778") -AnnotationAssertion(rdfs:label "pronephric nephron tubule epithelial cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (angioblast cell differentiation) - -AnnotationAssertion(Annotation( "CL:0000566") Annotation( "GOC:yaf") "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an angioblast cell. Angioblasts are one of the two products formed from hemangioblast cells (the other being pluripotent hemopoietic stem cells).") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-04-04T11:10:38Z") -AnnotationAssertion(Annotation( "CL:0000566") "angioblastic mesenchymal cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035779") -AnnotationAssertion(rdfs:label "angioblast cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cell migration involved in kidney development) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:mtg_kidney_jan10") Annotation( "GOC:yaf") "The orderly movement of a cell from one site to another that will contribute to the progression of the kidney over time, from its formation to the mature organ.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-04-06T10:39:52Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035787") -AnnotationAssertion(rdfs:label "cell migration involved in kidney development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cell migration involved in metanephros development) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:mtg_kidney_jan10") Annotation( "GOC:yaf") "The orderly movement of a cell from one site to another that will contribute to the progression of the metanephric kidney over time, from its formation to the mature organ.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-04-06T10:42:21Z") -AnnotationAssertion(Annotation( "GOC:bf") "cell migration involved in metanephric kidney development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035788") -AnnotationAssertion(rdfs:label "cell migration involved in metanephros development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (ureter maturation) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:mtg_kidney_jan10") Annotation( "GOC:yaf") Annotation( "PMID:17881463") "A developmental process, independent of morphogenetic (shape) change, that is required for the ureter to attain its fully functional state. The ureter is a muscular tube that transports urine from the kidney to the urinary bladder or from the Malpighian tubule to the hindgut.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-04-14T01:13:39Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035799") -AnnotationAssertion(rdfs:label "ureter maturation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (adrenal cortex development) - -AnnotationAssertion(Annotation( "PMID:12185666") Annotation( "PMID:21115154") Annotation( "Wikipedia:Adrenal_cortex") "The process whose specific outcome is the progression of the adrenal cortex over time, from its formation to the mature structure. The adrenal cortex is located at the periphery of the adrenal gland and controls glucose and electrolyte metabolism, response to stress and sexual development through the production of different classes of steroid hormones (glucocorticoids, mineralocorticoids and androgens).") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-04-18T10:25:39Z") -AnnotationAssertion(Annotation( "MA:0000118") "adrenal gland cortex development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035801") -AnnotationAssertion(rdfs:label "adrenal cortex development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (adrenal cortex formation) - -AnnotationAssertion(Annotation( "PMID:12185666") Annotation( "PMID:21115154") "The process that gives rise to the adrenal cortex. This process pertains to the initial formation of a structure from unspecified parts. The adrenogonadal primordium from which the adrenal cortex is formed derives from a condensation of coelomic epithelial cells (the urogenital ridge; the same structure from which gonads and kidney also originate).") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-04-18T10:26:49Z") -AnnotationAssertion(Annotation( "MA:0000118") "adrenal gland cortex formation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035802") -AnnotationAssertion(rdfs:label "adrenal cortex formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (egg coat formation) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:sart") Annotation( "GOC:yaf") Annotation( "PMID:16944418") Annotation( "PMID:17163408") "Construction of an egg coat, a specialized extracellular matrix that surrounds the ovum of animals. The egg coat provides structural support and can play an essential role in oogenesis, fertilization and early development.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-04-19T01:48:43Z") -AnnotationAssertion(Annotation( "PMID:16944418") Annotation( "PMID:17163408") "VE formation") -AnnotationAssertion(Annotation( "PMID:18420282") "ZP assembly") -AnnotationAssertion(Annotation( "PMID:16944418") "vitelline envelope formation") -AnnotationAssertion(Annotation( "GOC:yaf") Annotation( "PMID:18420282") "zona pellucida assembly") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035803") -AnnotationAssertion(rdfs:label "egg coat formation") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (egg coat) - -AnnotationAssertion(Annotation( "PMID:16944418") Annotation( "PMID:17163408") "A specialized extracellular matrix that surrounds the plasma membrane of the ovum of animals. The egg coat provides structural support and can play an essential role in oogenesis, fertilization and early development.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-04-19T02:07:23Z") -AnnotationAssertion(Annotation( "PMID:16944418") Annotation( "PMID:17163408") "vitelline membrane") -AnnotationAssertion(Annotation( "PMID:16944418") Annotation( "PMID:17163408") "zona pellucida") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0035805") -AnnotationAssertion(rdfs:label "egg coat") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) # Class: (regulation of urine volume) @@ -78346,202 +24411,6 @@ AnnotationAssertion(rdfs:label "regu SubClassOf( ) SubClassOf( ) -# Class: (indole alkaloid metabolic process) - -AnnotationAssertion(Annotation( "GOC:yaf") "The chemical reactions and pathways involving an indole alkaloid, an alkaloid containing an indole skeleton.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-05-04T03:17:44Z") -AnnotationAssertion(Annotation( "GOC:bf") "indole alkaloid metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035834") -AnnotationAssertion(rdfs:label "indole alkaloid metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (indole alkaloid biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:yaf") "The chemical reactions and pathways resulting in the formation of an indole alkaloid, an alkaloid containing an indole skeleton.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-05-04T03:18:31Z") -AnnotationAssertion(Annotation( "GOC:bf") "indole alkaloid anabolism") -AnnotationAssertion(Annotation( "GOC:bf") "indole alkaloid biosynthesis") -AnnotationAssertion(Annotation( "GOC:bf") "indole alkaloid formation") -AnnotationAssertion(Annotation( "GOC:bf") "indole alkaloid synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035835") -AnnotationAssertion(rdfs:label "indole alkaloid biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cloaca development) - -AnnotationAssertion(Annotation( "GOC:dgh") Annotation( "ISBN:0582227089") "The process whose specific outcome is the progression of the cloaca over time, from it's formation to the mature structure. The cloaca is the common chamber into which intestinal, genital and urinary canals open in vertebrates.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-05-06T01:54:35Z") -AnnotationAssertion(Annotation( "GOC:bf") "cloacal development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035844") -AnnotationAssertion(rdfs:label "cloaca development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (photoreceptor cell outer segment organization) - -AnnotationAssertion(Annotation( "ISBN:0824072820") Annotation( "PMID:14507858") "A process that is carried out at the cellular level and results in the assembly, arrangement of constituent parts, or disassembly of the outer segment of a photoreceptor cell, a sensory cell that reacts to the presence of light. The outer segment of the photoreceptor cell contains the light-absorbing materials.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-05-10T10:44:09Z") -AnnotationAssertion(Annotation( "GOC:mah") "photoreceptor cell outer segment organisation") -AnnotationAssertion(Annotation( "GOC:bf") "photoreceptor outer segment organization") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035845") -AnnotationAssertion(rdfs:label "photoreceptor cell outer segment organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (oviduct epithelium development) - -AnnotationAssertion(Annotation( "GOC:yaf") Annotation( "http://www.thefreedictionary.com/oviduct") "The progression of the oviduct epithelium over time from its initial formation to the mature structure. An oviduct is a tube through which an ova passes from the ovary to the uterus, or from the ovary to the outside of the organism. The oviduct epithelium is the specialized epithelium that lines the oviduct.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-05-10T10:53:05Z") -AnnotationAssertion(Annotation( "GOC:yaf") "fallopian tube epithelium development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035846") -AnnotationAssertion(rdfs:label "oviduct epithelium development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (uterine epithelium development) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:yaf") "The progression of an epithelium of the uterus over time from its initial formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-05-10T10:57:45Z") -AnnotationAssertion(Annotation( "GOC:yaf") "uterus epithelial development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035847") -AnnotationAssertion(rdfs:label "uterine epithelium development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (oviduct morphogenesis) - -AnnotationAssertion(Annotation( "GOC:yaf") Annotation( "http://www.thefreedictionary.com/oviduct") "The process in which anatomical structures of the oviduct are generated and organized. An oviduct is a tube through which an ova passes from the ovary to the uterus, or from the ovary to the outside of the organism.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-05-10T11:01:20Z") -AnnotationAssertion(Annotation( "GOC:yaf") "fallopian tube morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035848") -AnnotationAssertion(rdfs:label "oviduct morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (epithelial cell differentiation involved in kidney development) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:mtg_kidney_jan10") Annotation( "GOC:yaf") Annotation( "PMID:16216236") "The process in which relatively unspecialized cells acquire specialized structural and/or functional features of an epithelial cell that characterize the cells of the kidney as it progresses from its formation to the mature state.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-05-11T11:34:21Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035850") -AnnotationAssertion(rdfs:label "epithelial cell differentiation involved in kidney development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (megakaryocyte development) - -AnnotationAssertion(Annotation( "CL:0000556") Annotation( "GOC:BHF") Annotation( "GOC:vk") "The process whose specific outcome is the progression of a megakaryocyte cell over time, from its formation to the mature structure. Megakaryocyte development does not include the steps involved in committing a cell to a megakaryocyte fate. A megakaryocyte is a giant cell 50 to 100 micron in diameter, with a greatly lobulated nucleus, found in the bone marrow.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-05-13T01:28:06Z") -AnnotationAssertion(Annotation( "GOC:bf") "megakaryocyte cell development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035855") -AnnotationAssertion(rdfs:label "megakaryocyte development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (ciliary transition zone) - -AnnotationAssertion(Annotation( "GOC:cilia") Annotation( "GOC:kmv") Annotation( "PMID:21422230") "A region of the cilium between the basal body and proximal segment that is characterized by Y-shaped assemblages that connect axonemal microtubules to the ciliary membrane. The ciliary transition zone appears to function as a gate that controls ciliary membrane composition and separates the cytosol from the ciliary plasm.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-05-25T03:09:58Z") -AnnotationAssertion( "cilial transition zone") -AnnotationAssertion( "cilium transition zone") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "connecting cilium") -AnnotationAssertion( "GO:0035869") -AnnotationAssertion(rdfs:comment "Depending on the species, this region may have a distinct geometrically shaped electron-dense structure within the axonemal lumen visible in electron microscopy images; most animals don't display this inner structure. The axoneme extends through the ciliary transition zone, but only consists of the outer doublets. The central pair, axonemal spokes, and dynein complexes are not found in this part of the ciliary shaft. Note that the connecting cilium of the photoreceptor cells is thought to be equivalent to the transition zone.") -AnnotationAssertion(rdfs:label "ciliary transition zone") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (nail development) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "ISBN:0323025781") Annotation( "UBERON:0001705") Annotation( "Wikipedia:Nail_(anatomy)") "The process whose specific outcome is the progression of a nail over time, from its formation to the mature structure. A nail is a horn-like envelope covering the outer end of a finger or toe, and consists of the nail plate, the nail matrix and the nail bed below it, and the grooves surrounding it.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-05-31T02:30:34Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035878") -AnnotationAssertion(rdfs:label "nail development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (amacrine cell differentiation) - -AnnotationAssertion(Annotation( "CL:0000561") Annotation( "GOC:bf") "The process in which a relatively unspecialized cell acquires specialized features of an amacrine cell, an interneuron generated in the inner nuclear layer (INL) of the vertebrate retina. Amacrine cells integrate, modulate, and interpose a temporal domain in the visual message presented to the retinal ganglion cells, with which they synapse in the inner plexiform layer. Amacrine cells lack large axons.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-06-06T11:32:50Z") -AnnotationAssertion(Annotation( "CL:0000561") "amacrine neuron differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035881") -AnnotationAssertion(rdfs:label "amacrine cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (enteroendocrine cell differentiation) - -AnnotationAssertion(Annotation( "CL:0000164") Annotation( "GOC:bf") "The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of an enteroendocrine cell. Enteroendocrine cells are hormonally active epithelial cells in the gut that constitute the diffuse neuroendocrine system.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-06-06T11:48:51Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035883") -AnnotationAssertion(rdfs:label "enteroendocrine cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (vascular associated smooth muscle cell differentiation) - -AnnotationAssertion(Annotation( "GOC:sl") Annotation( "PMID:16151017") Annotation( "PMID:18267954") "The process in which a relatively unspecialized cell acquires specialized features of a vascular smooth muscle cell.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-06-08T11:23:52Z") -AnnotationAssertion(Annotation( "PMID:16151017") "VSMC differentiation") -AnnotationAssertion( "vascular smooth muscle cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035886") -AnnotationAssertion(rdfs:label "vascular associated smooth muscle cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (aortic smooth muscle cell differentiation) - -AnnotationAssertion(Annotation( "GOC:sl") "The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell surrounding the aorta.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-06-08T11:34:26Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035887") -AnnotationAssertion(rdfs:label "aortic smooth muscle cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - # Class: (parathyroid hormone secretion) AnnotationAssertion(Annotation( "GOC:cjm") Annotation( "PMID:12171519") Annotation( "PMID:21164021") "The regulated release of parathyroid hormone into the circulatory system.") @@ -78555,141 +24424,6 @@ AnnotationAssertion( "parathyroid hormone secretion") SubClassOf( ) -# Class: (aorta development) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:dgh") Annotation( "MA:0000062") Annotation( "UBERON:0000947") Annotation( "Wikipedia:Aorta") "The progression of the aorta over time, from its initial formation to the mature structure. An aorta is an artery that carries blood from the heart to other parts of the body.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-06-24T11:00:07Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035904") -AnnotationAssertion(rdfs:label "aorta development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (ascending aorta development) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:dgh") Annotation( "MA:0002570") Annotation( "UBERON:0001496") Annotation( "Wikipedia:Ascending_aorta") "The progression of the ascending aorta over time, from its initial formation to the mature structure. The ascending aorta is the portion of the aorta in a two-pass circulatory system that lies between the heart and the arch of aorta. In a two-pass circulatory system blood passes twice through the heart to supply the body once.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-06-24T11:02:01Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035905") -AnnotationAssertion(rdfs:label "ascending aorta development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (descending aorta development) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:dgh") Annotation( "MA:0002571") Annotation( "UBERON:0001514") Annotation( "Wikipedia:Descending_aorta") "The progression of the descending aorta over time, from its initial formation to the mature structure. The descending aorta is the portion of the aorta in a two-pass circulatory system from the arch of aorta to the point where it divides into the common iliac arteries. In a two-pass circulatory system blood passes twice through the heart to supply the body once.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-06-24T11:05:22Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035906") -AnnotationAssertion(rdfs:label "descending aorta development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (dorsal aorta development) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:dgh") Annotation( "UBERON:0005805") Annotation( "Wikipedia:Aorta") Annotation( "ZFA:0000014") "The progression of the dorsal aorta over time, from its initial formation to the mature structure. The dorsal aorta is a blood vessel in a single-pass circulatory system that carries oxygenated blood from the gills to the rest of the body. In a single-pass circulatory system blood passes once through the heart to supply the body once.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-06-24T11:07:01Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035907") -AnnotationAssertion(rdfs:label "dorsal aorta development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (ventral aorta development) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:dgh") Annotation( "UBERON:0003085") Annotation( "Wikipedia:Aorta") Annotation( "ZFA:0000604") "The progression of the ventral aorta over time, from its initial formation to the mature structure. The ventral aorta is a blood vessel in a single-pass circulatory system that carries de-oxygenated blood from the heart to the gills. In a single-pass circulatory system blood passes once through the heart to supply the body once.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-06-24T11:08:49Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035908") -AnnotationAssertion(rdfs:label "ventral aorta development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (aorta morphogenesis) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:dgh") Annotation( "MA:0000062") Annotation( "UBERON:0000947") Annotation( "Wikipedia:Aorta") "The process in which the anatomical structures of an aorta are generated and organized. An aorta is an artery that carries blood from the heart to other parts of the body.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-06-24T11:11:11Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035909") -AnnotationAssertion(rdfs:label "aorta morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (ascending aorta morphogenesis) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:dgh") Annotation( "MA:0002570") Annotation( "UBERON:0001496") Annotation( "Wikipedia:Ascending_aorta") "The process in which the anatomical structures of the ascending aorta are generated and organized. The ascending aorta is the portion of the aorta in a two-pass circulatory system that lies between the heart and the arch of aorta. In a two-pass circulatory system blood passes twice through the heart to supply the body once.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-06-24T11:14:52Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035910") -AnnotationAssertion(rdfs:label "ascending aorta morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (descending aorta morphogenesis) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:dgh") Annotation( "MA:0002571") Annotation( "UBERON:0001514") Annotation( "Wikipedia:Descending_aorta") "The process in which the anatomical structures of the descending aorta are generated and organized. The descending aorta is the portion of the aorta in a two-pass circulatory system from the arch of aorta to the point where it divides into the common iliac arteries. In a two-pass circulatory system blood passes twice through the heart to supply the body once.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-06-24T11:19:24Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035911") -AnnotationAssertion(rdfs:label "descending aorta morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (dorsal aorta morphogenesis) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:dgh") Annotation( "UBERON:0005805") Annotation( "Wikipedia:Aorta") Annotation( "ZFA:0000014") "The process in which the anatomical structures of the dorsal aorta are generated and organized. The dorsal aorta is a blood vessel in a single-pass circulatory system that carries oxygenated blood from the gills to the rest of the body. In a single-pass circulatory system blood passes once through the heart to supply the body once.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-06-24T11:22:14Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035912") -AnnotationAssertion(rdfs:label "dorsal aorta morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (ventral aorta morphogenesis) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:dgh") Annotation( "UBERON:0003085") Annotation( "Wikipedia:Aorta") Annotation( "ZFA:0000604") "The process in which the anatomical structures of the ventral aorta are generated and organized. The ventral aorta is a blood vessel in a single-pass circulatory system that carries de-oxygenated blood from the heart to the gills. In a single-pass circulatory system blood passes once through the heart to supply the body once.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-06-24T11:24:36Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035913") -AnnotationAssertion(rdfs:label "ventral aorta morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (skeletal muscle cell differentiation) - -AnnotationAssertion(Annotation( "CL:0000188") Annotation( "GOC:BHF") Annotation( "GOC:vk") "The process in which a relatively unspecialized cell acquires specialized features of a skeletal muscle cell, a somatic cell located in skeletal muscle.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-06-24T02:36:19Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035914") -AnnotationAssertion(rdfs:label "skeletal muscle cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (steroid hormone secretion) AnnotationAssertion(Annotation( "GOC:sl") "The regulated release of any steroid that acts as a hormone into the circulatory system.") @@ -78698,7 +24432,6 @@ AnnotationAssertion( AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0035929") AnnotationAssertion(rdfs:label "steroid hormone secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) @@ -78711,7 +24444,6 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:0035930") AnnotationAssertion(rdfs:label "corticosteroid hormone secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) # Class: (mineralocorticoid secretion) @@ -78722,7 +24454,6 @@ AnnotationAssertion( AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0035931") AnnotationAssertion(rdfs:label "mineralocorticoid secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) # Class: (aldosterone secretion) @@ -78733,146 +24464,9 @@ AnnotationAssertion( AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0035932") AnnotationAssertion(rdfs:label "aldosterone secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) -# Class: (glucocorticoid secretion) - -AnnotationAssertion(Annotation( "GOC:sl") "The regulated release of any glucocorticoid hormone into the circulatory system. Glucocorticoids are a class of steroid hormones that regulate a variety of physiological processes, in particular control of the concentration of glucose in blood.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-07-20T01:08:37Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035933") -AnnotationAssertion(rdfs:label "glucocorticoid secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (androgen secretion) - -AnnotationAssertion(Annotation( "GOC:sl") "The regulated release of an androgen into the circulatory system. Androgens are steroid hormones that stimulate or control the development and maintenance of masculine characteristics in vertebrates.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-07-20T01:11:31Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035935") -AnnotationAssertion(rdfs:label "androgen secretion") -SubClassOf( ) - -# Class: (testosterone secretion) - -AnnotationAssertion(Annotation( "GOC:sl") Annotation( "PMID:12606499") "The regulated release of testosterone into the circulatory system. Testosterone is an androgen having 17beta-hydroxy and 3-oxo groups, together with unsaturation at C-4-C-5.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-07-20T01:13:13Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035936") -AnnotationAssertion(rdfs:label "testosterone secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (tongue muscle cell differentiation) - -AnnotationAssertion(Annotation( "CL:0002673") Annotation( "GOC:yaf") Annotation( "PMID:3393851") "The process in which a relatively unspecialized cell acquires specialized features of a tongue muscle cell.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-08-22T01:35:16Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035981") -AnnotationAssertion(rdfs:label "tongue muscle cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (endodermal cell differentiation) - -AnnotationAssertion(Annotation( "CL:0000223") Annotation( "GOC:yaf") Annotation( "PMID:17624332") "The process in which a relatively unspecialized cell acquires the specialized features of an endoderm cell, a cell of the inner of the three germ layers of the embryo.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-08-25T04:50:36Z") -AnnotationAssertion(Annotation( "CL:0000223") "endoderm cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035987") -AnnotationAssertion(rdfs:label "endodermal cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (tendon development) - -AnnotationAssertion(Annotation( "GOC:yaf") Annotation( "PMID:21412429") Annotation( "UBERON:0000043") "The process whose specific outcome is the progression of a tendon over time, from its formation to the mature structure. A tendon is a fibrous, strong, connective tissue that connects muscle to bone or integument and is capable of withstanding tension. Tendons and muscles work together to exert a pulling force.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-08-26T04:14:30Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "UBERON:0000043") "sinew development") -AnnotationAssertion( "GO:0035989") -AnnotationAssertion(rdfs:label "tendon development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (tendon cell differentiation) - -AnnotationAssertion(Annotation( "CL:0000388") Annotation( "GOC:yaf") Annotation( "PMID:21412429") "The process in which a relatively unspecialized cell acquires the specialized features of a tendon cell. Tendon cell are elongated fibrocytes in which the cytoplasm is stretched between the collagen fibres of the tendon. Tendon cells have a central cell nucleus with a prominent nucleolus, a well-developed rough endoplasmic reticulum, and are responsible for synthesis and turnover of tendon fibres and ground substance.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-08-26T04:16:06Z") -AnnotationAssertion(Annotation( "CL:0000388") "muscle attachment cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "CL:0000388") "tenocyte differentiation") -AnnotationAssertion( "GO:0035990") -AnnotationAssertion(rdfs:label "tendon cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (tendon formation) - -AnnotationAssertion(Annotation( "GOC:yaf") Annotation( "PMID:17567668") Annotation( "UBERON:0000043") "The process that gives rise to a tendon. This process pertains to the initial formation of a tendon from unspecified parts.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-08-30T01:35:10Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035992") -AnnotationAssertion(rdfs:label "tendon formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (deltoid tuberosity development) - -AnnotationAssertion(Annotation( "GOC:yaf") Annotation( "PMID:17567668") Annotation( "UBERON:0002498") Annotation( "Wikipedia:Deltoid_tuberosity") "The process whose specific outcome is the progression of the deltoid tuberosity over time, from its formation to the mature structure. The deltoid tuberosity is the region on the shaft of the humerus to which the deltoid muscle attaches. The deltoid tuberosity develops through endochondral ossification in a two-phase process; an initiating tendon-dependent phase, and a muscle-dependent growth phase.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-08-30T01:46:53Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0035993") -AnnotationAssertion(rdfs:label "deltoid tuberosity development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (limb joint morphogenesis) - -AnnotationAssertion(Annotation( "GOC:bf") "The process in which the anatomical structures of a limb joint are generated and organized. A limb joint is a flexible region that separates the rigid sections of a limb to allow movement in a controlled manner.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-10-13T04:52:59Z") -AnnotationAssertion(Annotation( "GOC:bf") "knee morphogenesis") -AnnotationAssertion(Annotation( "GOC:bf") "leg joint morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0036022") -AnnotationAssertion(rdfs:label "limb joint morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (osteoclast development) - -AnnotationAssertion(Annotation( "CL:0000092") Annotation( "GOC:bf") Annotation( "GOC:yaf") "The process whose specific outcome is the progression of a osteoclast from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-11-02T05:20:35Z") -AnnotationAssertion(Annotation( "GOC:bf") "osteoclast cell development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0036035") -AnnotationAssertion(rdfs:label "osteoclast development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (direct ossification) AnnotationAssertion(Annotation( "GO_REF:0000034") "The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance, that does not require the replacement of preexisting tissues.") @@ -78904,65 +24498,6 @@ AnnotationAssertion( "replacement ossification") SubClassOf( ) -# Class: (germ cell proliferation) - -AnnotationAssertion(Annotation( "CL:0000586") Annotation( "GOC:kmv") "The multiplication or reproduction of germ cells, reproductive cells in multicellular organisms, resulting in the expansion of a cell population.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2012-01-17T04:06:27Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0036093") -AnnotationAssertion(rdfs:label "germ cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (small molecule binding) - -AnnotationAssertion(Annotation( "GOC:curators") Annotation( "GOC:pde") Annotation( "GOC:pm") "Binding to a small molecule, any low molecular weight, monomeric, non-encoded molecule.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2012-01-17T04:20:34Z") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0036094") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "Small molecules in GO include monosaccharides but exclude disaccharides and polysaccharides.") -AnnotationAssertion(rdfs:label "small molecule binding") -SubClassOf( ) - -# Class: (female germ-line stem cell population maintenance) - -AnnotationAssertion(Annotation( "GOC:sart") "The process by which an organism or tissue maintains a population of female germ-line stem cells.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2012-01-26T01:58:10Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0036099") -AnnotationAssertion(rdfs:label "female germ-line stem cell population maintenance") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (Schwann cell migration) - -AnnotationAssertion(Annotation( "CL:0002573") Annotation( "PMID:20335460") "The orderly movement of a Schwann cell from one site to another. A Schwann cell is a glial cell that ensheathes axons of neuron in the peripheral nervous system and is necessary for their maintainance and function.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2012-03-06T10:44:39Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0036135") -AnnotationAssertion(rdfs:label "Schwann cell migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (dendritic cell homeostasis) - -AnnotationAssertion(Annotation( "CL:0000451") Annotation( "GOC:uh") Annotation( "PMID:12570827") Annotation( "PMID:19176316") "The process of regulating the proliferation and elimination of dendritic cells such that the total number of dendritic cells within a whole or part of an organism is stable over time in the absence of an outside stimulus.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2012-03-12T11:05:36Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "PMID:19176316") "DC homeostasis") -AnnotationAssertion( "GO:0036145") -AnnotationAssertion(rdfs:label "dendritic cell homeostasis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - # Class: (rumination) AnnotationAssertion(Annotation( "GOC:maf") Annotation( "Wikipedia:Rumination") "A digestive process in which food, usually grass or hay, is swallowed into a multi-compartmented stomach, regurgitated, chewed again, and swallowed again.") @@ -78974,17 +24509,6 @@ AnnotationAssertion( "rumination") SubClassOf( ) -# Class: (melanocyte-stimulating hormone secretion) - -AnnotationAssertion(Annotation( "GOC:cjm") Annotation( "Wikipedia:Melanocyte-stimulating_hormone") "The regulated release of a melanocyte-stimulating hormone, any of a group of peptide hormones that are produced by cells in the intermediate lobe of the pituitary gland, and stimulate the production of melanin to increase pigmentation.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2012-03-26T01:16:55Z") -AnnotationAssertion(Annotation( "GOC:cjm") "MSH secretion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0036160") -AnnotationAssertion(rdfs:label "melanocyte-stimulating hormone secretion") -SubClassOf( ) - # Class: (calcitonin secretion) AnnotationAssertion(Annotation( "GOC:cjm") "The regulated release of calcitonin, a peptide hormone that participates in calcium and phosphorus metabolism, from a cell.") @@ -78993,22 +24517,8 @@ AnnotationAssertion( AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0036161") AnnotationAssertion(rdfs:label "calcitonin secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (osteoclast maturation) - -AnnotationAssertion(Annotation( "CL:0000092") Annotation( "GOC:pg") "A developmental process, independent of morphogenetic (shape) change, that is required for an osteoclast cell to attain its fully functional state. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue, and which typically differentiates from monocytes.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2012-03-29T02:04:00Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "CL:0000092") "chondroclast maturation") -AnnotationAssertion( "GO:0036179") -AnnotationAssertion(rdfs:label "osteoclast maturation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (muscle cell projection) AnnotationAssertion(Annotation( "CL:0000187") Annotation( "GOC:kmv") Annotation( "PMID:15930100") Annotation( "PMID:22464329") "A prolongation or process extending from a muscle cell. A muscle cell is a mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns.") @@ -79020,50 +24530,6 @@ AnnotationAssertion(Annotation( "cellular_component") AnnotationAssertion( "GO:0036194") AnnotationAssertion(rdfs:label "muscle cell projection") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (muscle cell projection membrane) - -AnnotationAssertion(Annotation( "CL:0000187") Annotation( "GOC:kmv") Annotation( "PMID:15930100") Annotation( "PMID:22464329") "The portion of the plasma membrane surrounding a muscle cell projection.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2012-04-20T10:21:51Z") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0036195") -AnnotationAssertion(rdfs:label "muscle cell projection membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (protein modification process) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:jl") "The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications). Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification).") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/23112"^^xsd:anyURI) -AnnotationAssertion( "bf") -AnnotationAssertion( "2012-04-26T01:47:12Z") -AnnotationAssertion( "GO:0006464") -AnnotationAssertion( "cellular protein modification process") -AnnotationAssertion( "process resulting in protein modification") -AnnotationAssertion(Annotation( "GOC:bf") "protein modification") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0036211") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "protein modification process") -SubClassOf( ) -SubClassOf( ) - -# Class: (granulocyte activation) - -AnnotationAssertion(Annotation( "CL:0000094") Annotation( "GOC:nhn") "The change in morphology and behavior of a granulocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2012-05-11T10:57:48Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0036230") -AnnotationAssertion(rdfs:label "granulocyte activation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) # Class: (response to decreased oxygen levels) @@ -79077,138 +24543,6 @@ AnnotationAssertion(rdfs:comment "Th AnnotationAssertion(rdfs:label "response to decreased oxygen levels") SubClassOf( ) -# Class: (atrioventricular canal development) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:gr") Annotation( "PMID:14701881") Annotation( "UBERON:0002087") Annotation( "ZFA:0001315") "The progression of the atrioventricular canal over time, from its formation to the mature structure. The atrioventricular canal is the part of the heart connecting the atrium to the cardiac ventricle.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2012-08-08T09:55:37Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0036302") -AnnotationAssertion(rdfs:label "atrioventricular canal development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (lymph vessel morphogenesis) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:gr") Annotation( "PMID:18093989") "The process in which the anatomical structures of lymph vessels are generated and organized. The lymph vessel is the vasculature carrying lymph.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2012-08-08T10:08:47Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0036303") -AnnotationAssertion(rdfs:label "lymph vessel morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (umbilical cord morphogenesis) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:gr") Annotation( "PMID:15107403") "The process in which the anatomical structures of the umbilical cord are generated and organized. The umbilical cord is an organ or embryonic origin consisting of the 2 umbilical arteries and the one umbilical vein. The umbilical cord connects the cardiovascular system of the fetus to the mother via the placenta.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2012-08-08T10:12:11Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0036304") -AnnotationAssertion(rdfs:label "umbilical cord morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (ameloblast differentiation) - -AnnotationAssertion(Annotation( "CL:0000059") "The process in which a relatively unspecialized cell acquires specialized features of an ameloblast, a cylindrical epithelial cell in the innermost layer of the enamel organ.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2012-08-08T13:49:15Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0036305") -AnnotationAssertion(rdfs:label "ameloblast differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (hepatocyte homeostasis) - -AnnotationAssertion(Annotation( "CL:0000182") Annotation( "GOC:nhn") Annotation( "PMID:19878874") "Any biological process involved in the maintenance of the steady-state number of hepatocytes within a population of cells. Hepatocytes are specialized epithelial cells of the liver that are organized into interconnected plates called lobules.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2012-09-05T10:17:07Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0036333") -AnnotationAssertion(rdfs:label "hepatocyte homeostasis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (epidermal stem cell homeostasis) - -AnnotationAssertion(Annotation( "CL:1000428") Annotation( "GOC:nhn") Annotation( "PMID:17666529") "Any biological process involved in the maintenance of the steady-state number of epidermal stem cells within a population of cells.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2012-09-05T10:21:23Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0036334") -AnnotationAssertion(rdfs:label "epidermal stem cell homeostasis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (dendritic cell migration) - -AnnotationAssertion(Annotation( "CL:0000451") Annotation( "GOC:nhn") Annotation( "PMID:19339990") "The movement of a dendritic cell within or between different tissues and organs of the body.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2012-09-05T10:24:46Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0036336") -AnnotationAssertion(rdfs:label "dendritic cell migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (post-anal tail morphogenesis) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:kmv") Annotation( "Wikipedia:Chordate") "The process in which a post-anal tail is generated and organized. A post-anal tail is a muscular region of the body that extends posterior to the anus. The post-anal tail may aid locomotion and balance.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2012-09-11T13:54:49Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0036342") -AnnotationAssertion(rdfs:label "post-anal tail morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - -# Class: (platelet morphogenesis) - -AnnotationAssertion(Annotation( "CL:0000233") Annotation( "GOC:BHF") Annotation( "GOC:vk") "Generation and organization of a platelet, a non-nucleated disk-shaped cell formed by extrusion from megakaryocytes, found in the blood of all mammals, and mainly involved in blood coagulation.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2012-09-11T15:15:35Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0036344") -AnnotationAssertion(rdfs:label "platelet morphogenesis") -SubClassOf( ) - -# Class: (platelet maturation) - -AnnotationAssertion(Annotation( "CL:0000233") Annotation( "GOC:BHF") Annotation( "GOC:vk") "A developmental process, independent of morphogenetic (shape) change, that is required for a platelet to attain its fully functional state. A platelet is a non-nucleated disk-shaped cell formed by extrusion from megakaryocytes, found in the blood of all mammals, and mainly involved in blood coagulation.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2012-09-11T15:23:11Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0036345") -AnnotationAssertion(rdfs:label "platelet maturation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (sodium ion export across plasma membrane) - -AnnotationAssertion(Annotation( "GOC:vw") Annotation( "PMID:14674689") "The directed movement of sodium ions from inside of a cell, across the plasma membrane and into the extracellular region.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2009-12-16T11:13:55Z") -AnnotationAssertion( "GO:0071436") -AnnotationAssertion( "GO:0098667") -AnnotationAssertion( "sodium ion export from cell") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:mah") "sodium export") -AnnotationAssertion( "sodium ion export") -AnnotationAssertion( "GO:0036376") -AnnotationAssertion(rdfs:label "sodium ion export across plasma membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - # Class: (myofilament) AnnotationAssertion(Annotation( "Wikipedia:Myofilament") "Any of the smallest contractile units of a myofibril (striated muscle fiber).") @@ -79233,372 +24567,6 @@ AnnotationAssertion(rdfs:label "soma SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (trunk neural crest cell migration) - -AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:bf") Annotation( "GOC:mat") Annotation( "PMID:2387238") "The characteristic movement of trunk neural crest cells from the neural tube to other locations in the vertebrate embryo.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2014-08-26T15:27:44Z") -AnnotationAssertion(Annotation( "PMID:2387238") "trunk NCC migration") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0036484") -AnnotationAssertion(rdfs:label "trunk neural crest cell migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (Golgi membrane fusion) - -AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:bf") Annotation( "PMID:12473691") "The joining of two lipid bilayers that surround the Golgi apparatus to form a single Golgi membrane.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2015-05-21T10:05:06Z") -AnnotationAssertion( "Golgi apparatus membrane fusion") -AnnotationAssertion(Annotation( "GOC:bf") "membrane fusion involved in Golgi reassembly") -AnnotationAssertion(Annotation( "PMID:10811609") "post-mitotic fusion of Golgi membranes") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0036504") -AnnotationAssertion(rdfs:label "Golgi membrane fusion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (astrocyte-dopaminergic neuron signaling) - -AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:bf") Annotation( "PMID:12794311") Annotation( "PMID:21752258") "Cell-cell signaling that mediates the transfer of information from an astrocyte to a dopaminergic neuron.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2016-02-29T14:05:47Z") -AnnotationAssertion(Annotation( "GOC:bf") "astrocyte-dopaminergic neuron cell signaling") -AnnotationAssertion(Annotation( "PMID:21752258") "mesencephalic dopaminergic neuron-astrocyte crosstalk") -AnnotationAssertion(Annotation( "PMID:21752258") "midbrain dopaminergic neuron-astrocyte crosstalk") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "PMID:21752258") "dopaminergic neuron-astrocyte crosstalk") -AnnotationAssertion( "GO:0036520") -AnnotationAssertion(rdfs:label "astrocyte-dopaminergic neuron signaling") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (signaling receptor activity) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:signaling") "Receiving a signal and transmitting it in the cell to initiate a change in cell activity. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-08-01T02:45:27Z") -AnnotationAssertion( "GO:0004872") -AnnotationAssertion( "GO:0019041") -AnnotationAssertion( "receptor activity") -AnnotationAssertion(Annotation( "GOC:bf") "receptor activity involved in signal transduction") -AnnotationAssertion( "signalling receptor activity") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0038023") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "signaling receptor activity") -SubClassOf( ) - -# Class: (prolactin signaling pathway) - -AnnotationAssertion(Annotation( "GOC:nhn") Annotation( "GOC:signaling") Annotation( "PMID:21664429") "The series of molecular signals initiated by the binding of the peptide hormone prolactin to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.") -AnnotationAssertion( ) -AnnotationAssertion( "bf") -AnnotationAssertion( "2012-05-14T01:52:59Z") -AnnotationAssertion(Annotation( "PMID:21664429") Annotation( "PR:000013246") "PRL signaling pathway") -AnnotationAssertion(Annotation( "GOC:bf") "prolactin-mediated signaling pathway") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0038161") -AnnotationAssertion(rdfs:label "prolactin signaling pathway") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) -DisjointClasses( ObjectSomeValuesFrom( )) - -# Class: (somatostatin receptor signaling pathway) - -AnnotationAssertion(Annotation( "GOC:jc") Annotation( "PMID:18006219") Annotation( "PMID:8769369") "A G protein-coupled receptor signaling pathway initiated by somatostatin binding to the somatostatin receptor (SSTR) on the surface of a target cell, and ending with the regulation of a downstream cellular process.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2012-06-12T10:30:01Z") -AnnotationAssertion(Annotation( "GOC:bf") "SST receptor signaling pathway") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:bf") "SSTR signaling pathway") -AnnotationAssertion( "GO:0038169") -AnnotationAssertion(rdfs:comment "In addition to somatostatin (SST), the somatostatin receptors (SSTRs) can also be activated by the agonist cortistatin (CST). For signal transduction specifically initiated by the ligand somatostatin, consider instead annotating to the child term 'somatostatin signaling pathway ; GO:0038170'.") -AnnotationAssertion(rdfs:label "somatostatin receptor signaling pathway") -SubClassOf( ) - -# Class: (somatostatin signaling pathway) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:nhn") Annotation( "GOC:signaling") Annotation( "PMID:18006219") Annotation( "Wikipedia:Somatostatin") "A G protein-coupled receptor signaling pathway initiated by somatostatin binding to a somatostatin receptor (SSTR), and ending with the regulation of a downstream cellular process, e.g. transcription.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2012-06-12T10:33:21Z") -AnnotationAssertion(Annotation( "Wikipedia:Somatostatin") "SRIF signaling pathway") -AnnotationAssertion(Annotation( "Wikipedia:Somatostatin") "SST signaling pathway") -AnnotationAssertion(Annotation( "GOC:bf") "somatostatin signalling pathway") -AnnotationAssertion(Annotation( "GOC:bf") "somatostatin-activated somatostatin receptor signaling pathway") -AnnotationAssertion(Annotation( "GOC:bf") "somatostatin-mediated signaling pathway") -AnnotationAssertion(Annotation( "Wikipedia:Somatostatin") "somatotrophin release inhibiting factor signaling pathway") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0038170") -AnnotationAssertion(rdfs:label "somatostatin signaling pathway") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (pattern recognition receptor activity) - -AnnotationAssertion(Annotation( "GOC:ar") Annotation( "GOC:bf") "Combining with a pathogen-associated molecular pattern (PAMP), a structure conserved among microbial species to initiate an innate immune response.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/17995"^^xsd:anyURI) -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/18588"^^xsd:anyURI) -AnnotationAssertion( "bf") -AnnotationAssertion( "2013-05-29T15:24:44Z") -AnnotationAssertion( "GO:0008329") -AnnotationAssertion( "Wikipedia:Pattern_recognition_receptor") -AnnotationAssertion( "PRR") -AnnotationAssertion(Annotation( "Wikipedia:Pattern_recognition_receptor") "PRR activity") -AnnotationAssertion( "MAMP receptor activity") -AnnotationAssertion( "PAMP receptor activity") -AnnotationAssertion( "microbe-associated molecular pattern receptor activity") -AnnotationAssertion( "pathogen associated molecular pattern receptor activity") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "macrophage receptor activity") -AnnotationAssertion( "signaling pattern recognition receptor activity") -AnnotationAssertion( "GO:0038187") -AnnotationAssertion(rdfs:label "pattern recognition receptor activity") -SubClassOf( ) - -# Class: (pronephric nephron tubule formation) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The developmental process pertaining to the initial formation of a pronephric nephron tubule from unspecified parts. A pronephric nephron tubule is an epithelial tube that is part of a nephron in the pronephros.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2010-07-02T09:37:27Z") -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "pronephric tubule formation") -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "pronephros tubule formation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0039006") -AnnotationAssertion(rdfs:label "pronephric nephron tubule formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (pronephric nephron morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the anatomical structures of the pronephric nephron are generated and organized. A pronephric nephron is the functional unit of the pronephros.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2010-07-02T09:38:53Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0039007") -AnnotationAssertion(rdfs:label "pronephric nephron morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (pronephric nephron tubule morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") Annotation( "ZFA:00001558") "The process in which the anatomical structures of a pronephric nephron tubule are generated and organized from an epithelium. A pronephric nephron tubule is an epithelial tube that is part of the pronephric nephron.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2010-07-02T09:45:55Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0039008") -AnnotationAssertion(rdfs:label "pronephric nephron tubule morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (rectal diverticulum development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") Annotation( "PMID:10535314") Annotation( "PMID:18226983") Annotation( "XAO:0001015") "The process whose specific outcome is the progression of the rectal diverticulum over time, from its formation to the mature structure. The rectal diverticulum is an outgrowth of the cloaca and links the pronephric kidney to the exterior.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2010-07-02T09:48:58Z") -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "pronephric rectal diverticulum development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0039009") -AnnotationAssertion(rdfs:label "rectal diverticulum development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (pronephric proximal tubule morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the anatomical structures of a pronephric nephron proximal tubule are generated and organized. A pronephric nephron tubule is an epithelial tube that is part of the pronephros.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2010-07-02T09:53:12Z") -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "pronephros proximal tubule morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0039011") -AnnotationAssertion(rdfs:label "pronephric proximal tubule morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (pronephric distal tubule morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the anatomical structures of a pronephric nephron distal tubule are generated and organized. A pronephric nephron tubule is an epithelial tube that is part of the pronephros.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2010-07-02T09:58:03Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0039013") -AnnotationAssertion(rdfs:label "pronephric distal tubule morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cell differentiation involved in pronephros development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the pronephros as it progresses from its formation to the mature state.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2010-07-02T09:59:25Z") -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "cell differentiation involved in pronephric kidney development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0039014") -AnnotationAssertion(rdfs:label "cell differentiation involved in pronephros development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cell proliferation involved in pronephros development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The multiplication or reproduction of cells, resulting in the expansion of the population in the pronephros.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2010-07-02T10:01:49Z") -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "cell proliferation involved in pronephric kidney development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0039015") -AnnotationAssertion(rdfs:label "cell proliferation involved in pronephros development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cell-cell signaling involved in pronephros development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "Any process that mediates the transfer of information from one cell to another and contributes to the progression of the pronephros over time, from its formation to the mature organ.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2010-07-02T10:03:16Z") -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "cell-cell signaling involved in pronephric kidney development") -AnnotationAssertion(Annotation( "GOC:mah") "cell-cell signalling involved in pronephros development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0039016") -AnnotationAssertion(rdfs:label "cell-cell signaling involved in pronephros development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (pattern specification involved in pronephros development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "Any developmental process that results in the creation of defined areas or spaces within the pronephros to which cells respond and eventually are instructed to differentiate.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2010-07-02T10:04:39Z") -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "pattern specification involved in pronephric kidney development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0039017") -AnnotationAssertion(rdfs:label "pattern specification involved in pronephros development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (nephrostome development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") Annotation( "PMID:14686690") Annotation( "PMID:15647339") Annotation( "XAO:0000062") "The process whose specific outcome is the progression of the nephrostome over time, from its formation to the mature structure. The nephrostome is the opening of the pronephros into the body cavity.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2010-07-02T10:08:16Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0039018") -AnnotationAssertion(rdfs:label "nephrostome development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (pronephric nephron development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") Annotation( "XAO:00002785") "The process whose specific outcome is the progression of the pronephric nephron over time, from its formation to the mature structure. A pronephric nephron is the functional unit of the pronephros.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2010-07-02T10:10:20Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0039019") -AnnotationAssertion(rdfs:label "pronephric nephron development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (pronephric nephron tubule development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") Annotation( "PMID:19909807") Annotation( "PMID:9268568") "The process whose specific outcome is the progression of a pronephric nephron tubule over time, from its formation to the mature structure. The pronephric nephron tubule is an epithelial tube that is part of the pronephric nephron and connects the filtration unit (glomerulus or glomus) of the pronephros to the pronephric duct.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2010-07-02T10:11:36Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0039020") -AnnotationAssertion(rdfs:label "pronephric nephron tubule development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (pronephric glomerulus development) - -AnnotationAssertion(Annotation( "GOC:dgh") Annotation( "GOC:mtg_kidney_jan10") Annotation( "ZFA:00001557") "The progression of the glomerulus of the pronephric kidney over time from its initial formation until its mature state. The pronephric glomerulus is part of the pronephric nephron and is restricted to one body segment.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2010-07-02T10:13:38Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0039021") -AnnotationAssertion(rdfs:comment "This term is intended for annotation of fish and other organisms which contain a glomerulus as part of the pronephric nephron. It should not be used for annotation of Xenopus, which contains a pronephric glomus rather than a glomerulus.") -AnnotationAssertion(rdfs:label "pronephric glomerulus development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (pronephric duct development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") Annotation( "PMID:15647339") Annotation( "XAO:0000063") Annotation( "ZFA:0000150") "The process whose specific outcome is the progression of the pronephric duct over time, from its formation to the mature structure. The pronephric duct collects the filtrate from the pronephric tubules and opens to the exterior of the pronephric kidney.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2010-07-02T10:15:03Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0039022") -AnnotationAssertion(rdfs:label "pronephric duct development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (pronephric duct morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") Annotation( "XAO:0000063") Annotation( "ZFA:0000150") "The process in which the anatomical structures of the pronephric duct are generated and organized. The pronephric duct collects the filtrate from the pronephric tubules and opens to the exterior of the kidney.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2010-07-02T10:18:09Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0039023") -AnnotationAssertion(rdfs:label "pronephric duct morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (collagen and cuticulin-based cuticle development) - -AnnotationAssertion(Annotation( "GOC:mtg_sensu") "Synthesis and deposition of a collagen and cuticulin-based noncellular, hardened, or membranous secretion from an epithelial sheet. An example of this process is found in Caenorhabditis elegans.") -AnnotationAssertion( "collagen and cuticulin-based cuticle anabolism") -AnnotationAssertion( "collagen and cuticulin-based cuticle biosynthetic process") -AnnotationAssertion( "collagen and cuticulin-based cuticle formation") -AnnotationAssertion( "collagen and cuticulin-based cuticle synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0040002") -AnnotationAssertion(rdfs:label "collagen and cuticulin-based cuticle development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - -# Class: (chitin-based cuticle development) - -AnnotationAssertion(Annotation( "GOC:mtg_sensu") "Synthesis and deposition of a chitin-based noncellular, hardened, or membranous secretion from an epithelial sheet. An example of this process is found in Drosophila melanogaster.") -AnnotationAssertion( "chitin-based cuticle anabolism") -AnnotationAssertion( "chitin-based cuticle biosynthetic process") -AnnotationAssertion( "chitin-based cuticle formation") -AnnotationAssertion( "chitin-based cuticle synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0040003") -AnnotationAssertion(rdfs:label "chitin-based cuticle development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - # Class: (growth) AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:ma") "The increase in size or mass of an entire organism, a part of an organism or a cell.") @@ -79618,15 +24586,6 @@ SubClassOf( ObjectSomeValuesFrom( ObjectAllValuesFrom( )) DisjointClasses( ) -# Class: (regulation of growth) - -AnnotationAssertion(Annotation( "GOC:ems") Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the growth of all or part of an organism so that it occurs at its proper speed, either globally or in a specific part of the organism's development.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0040008") -AnnotationAssertion(rdfs:label "regulation of growth") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - # Class: (locomotion) AnnotationAssertion(Annotation( "GOC:dgh") "Self-propelled movement of a cell or organism from one location to another.") @@ -79648,43 +24607,8 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:0040012") AnnotationAssertion(rdfs:label "regulation of locomotion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (negative regulation of locomotion) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of locomotion of a cell or organism.") -AnnotationAssertion( "down regulation of locomotion") -AnnotationAssertion( "down-regulation of locomotion") -AnnotationAssertion( "downregulation of locomotion") -AnnotationAssertion( "inhibition of locomotion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0040013") -AnnotationAssertion(rdfs:label "negative regulation of locomotion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of multicellular organism growth) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:ems") Annotation( "GOC:tb") "Any process that modulates the frequency, rate or extent of growth of the body of an organism so that it reaches its usual body size.") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "regulation of body growth") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "regulation of body size") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0040014") -AnnotationAssertion(rdfs:label "regulation of multicellular organism growth") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of multicellular organism growth) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:ems") Annotation( "GOC:tb") "Any process that stops, prevents, or reduces the frequency, rate or extent of growth of an organism to reach its usual body size.") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "negative regulation of body growth") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "negative regulation of body size") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0040015") -AnnotationAssertion(rdfs:label "negative regulation of multicellular organism growth") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (embryonic cleavage) AnnotationAssertion(Annotation( "GOC:clt") Annotation( "ISBN:0070524300") "The first few specialized divisions of an activated animal egg.") @@ -79705,58 +24629,9 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0040017") AnnotationAssertion(rdfs:label "positive regulation of locomotion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) -# Class: (positive regulation of multicellular organism growth) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:go_curators") Annotation( "GOC:tb") "Any process that activates or increases the frequency, rate or extent of growth of an organism to reach its usual body size.") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "positive regulation of body growth") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "positive regulation of body size") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0040018") -AnnotationAssertion(rdfs:label "positive regulation of multicellular organism growth") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of embryonic development) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of embryonic development.") -AnnotationAssertion( "up regulation of embryonic development") -AnnotationAssertion( "up-regulation of embryonic development") -AnnotationAssertion( "upregulation of embryonic development") -AnnotationAssertion( "activation of embryonic development") -AnnotationAssertion( "stimulation of embryonic development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0040019") -AnnotationAssertion(rdfs:label "positive regulation of embryonic development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of meiotic nuclear division) - -AnnotationAssertion(Annotation( "GOC:ems") Annotation( "GOC:ma") "Any process that modulates the frequency, rate or extent of meiotic nuclear division, the process in which the nucleus of a diploid cell divides twice forming four haploid cells, one or more of which usually function as gametes.") -AnnotationAssertion(Annotation( "GOC:vw") "regulation of meiosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0040020") -AnnotationAssertion(rdfs:label "regulation of meiotic nuclear division") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (regulation of development, heterochronic) - -AnnotationAssertion(Annotation( "PMID:9442909") "Any process that modulates the consistent predetermined time point at which an integrated living unit or organism progresses from an initial condition to a later condition and the rate at which this time point is reached.") -AnnotationAssertion( "heterochronic regulation of development") -AnnotationAssertion( "temporal regulation of development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "developmental timing") -AnnotationAssertion( "GO:0040034") -AnnotationAssertion(rdfs:label "regulation of development, heterochronic") -SubClassOf( ) - # Class: (fluid transport) AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of substances that are in liquid form in normal living conditions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") @@ -79766,14 +24641,6 @@ AnnotationAssertion( "fluid transport") SubClassOf( ) -# Class: (epithelial fluid transport) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "PMID:11390830") "The directed movement of fluid across epithelia.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042045") -AnnotationAssertion(rdfs:label "epithelial fluid transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (olfactory behavior) AnnotationAssertion(Annotation( "GOC:jid") Annotation( "GOC:pr") "The behavior of an organism in response to an odor.") @@ -79788,15 +24655,6 @@ AnnotationAssertion( "olfactory behavior") SubClassOf( ) -# Class: (regulation of dopamine metabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving dopamine.") -AnnotationAssertion( "regulation of dopamine metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042053") -AnnotationAssertion(rdfs:label "regulation of dopamine metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (wound healing) AnnotationAssertion(Annotation( "GOC:bf") Annotation( "PMID:15269788") "The series of events that restore integrity to a damaged tissue, following an injury.") @@ -79808,124 +24666,6 @@ AnnotationAssertion(rdfs:label "woun SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (gliogenesis) - -AnnotationAssertion(Annotation( "GOC:dgh") Annotation( "GOC:jid") "The process that results in the generation of glial cells. This includes the production of glial progenitors and their differentiation into mature glia.") -AnnotationAssertion(Annotation( ) "glial cell generation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042063") -AnnotationAssertion(rdfs:label "gliogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (glial cell growth) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:isa_complete") Annotation( "GOC:jid") "Growth of glial cells, non-neuronal cells that provide support and nutrition, maintain homeostasis, form myelin, and participate in signal transmission in the nervous system.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042065") -AnnotationAssertion(rdfs:label "glial cell growth") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (regulation of catecholamine metabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving catecholamines.") -AnnotationAssertion( "regulation of catecholamine metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042069") -AnnotationAssertion(rdfs:label "regulation of catecholamine metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (intraciliary transport) - -AnnotationAssertion(Annotation( "GOC:cilia") Annotation( "GOC:kmv") Annotation( "PMID:17981739") Annotation( "PMID:18180368") Annotation( "PMID:22869374") Annotation( "Reactome:R-HSA-5620924.2") "The bidirectional movement of large protein complexes along microtubules within a cilium, mediated by motor proteins.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "GO:0035734") -AnnotationAssertion( "Wikipedia:Intraflagellar_transport") -AnnotationAssertion( "intraflagellar transport") -AnnotationAssertion( "intraflagellar transport involved in cilium organization") -AnnotationAssertion( "intraflagellar transport involved in microtubule-based flagellum organisation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "IFT") -AnnotationAssertion( "GO:0042073") -AnnotationAssertion(rdfs:comment "Note that we deem cilium and microtubule-based flagellum to be equivalent.") -AnnotationAssertion(rdfs:label "intraciliary transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) -SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) -SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) -SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) -SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) -SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) -SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) -SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) -SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) -SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) -SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) -SubClassOf( ObjectAllValuesFrom( )) -DisjointClasses( ObjectSomeValuesFrom( )) -DisjointClasses( ObjectSomeValuesFrom( )) -DisjointClasses( ObjectSomeValuesFrom( )) -DisjointClasses( ObjectSomeValuesFrom( )) -DisjointClasses( ObjectSomeValuesFrom( )) -DisjointClasses( ObjectSomeValuesFrom( )) - -# Class: (cell migration involved in gastrulation) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0878932437") Annotation( "http://www.cellmigration.org/") "The migration of individual cells within the blastocyst to help establish the multi-layered body plan of the organism (gastrulation). For example, the migration of cells from the surface to the interior of the embryo (ingression).") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042074") -AnnotationAssertion(rdfs:label "cell migration involved in gastrulation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (germ-line stem cell division) - -AnnotationAssertion(Annotation( "GOC:jid") Annotation( "PMID:2279698") "The self-renewing division of a germline stem cell to produce a daughter stem cell and a daughter germ cell, which will divide to form the gametes.") -AnnotationAssertion( "GO:0048131") -AnnotationAssertion( "germ-line stem cell renewal") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042078") -AnnotationAssertion(rdfs:label "germ-line stem cell division") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (type 2 immune response) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") Annotation( "PMID:18000958") Annotation( "PMID:18007680") Annotation( "PMID:20065995") Annotation( "PMID:20200518") "An immune response which is associated with resistance to extracellular organisms such as helminths and pathological conditions such as allergy, which is orchestrated by the production of particular cytokines, most notably IL-4, IL-5, IL-10, and IL-13, by any of a variety of cell types including T-helper 2 cells, eosinophils, basophils, mast cells, and nuocytes, resulting in enhanced production of certain antibody isotypes and other effects.") -AnnotationAssertion(Annotation( "GOC:add") "T-helper 2 type immune response") -AnnotationAssertion(Annotation( "GOC:add") "Th2 immune response") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042092") -AnnotationAssertion(rdfs:label "type 2 immune response") -SubClassOf( ) - -# Class: (T cell proliferation) - -AnnotationAssertion(Annotation( "GOC:jl") "The expansion of a T cell population by cell division. Follows T cell activation.") -AnnotationAssertion( "GO:0042111") -AnnotationAssertion( "T lymphocyte proliferation") -AnnotationAssertion( "T-cell proliferation") -AnnotationAssertion( "T-lymphocyte proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042098") -AnnotationAssertion(rdfs:label "T cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - # Class: (B cell proliferation) AnnotationAssertion(Annotation( "GOC:jl") "The expansion of a B cell population by cell division. Follows B cell activation.") @@ -79936,42 +24676,9 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0042100") AnnotationAssertion(rdfs:label "B cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) -# Class: (positive regulation of T cell proliferation) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the rate or extent of T cell proliferation.") -AnnotationAssertion( "positive regulation of T lymphocyte proliferation") -AnnotationAssertion( "positive regulation of T-lymphocyte proliferation") -AnnotationAssertion( "up regulation of T cell proliferation") -AnnotationAssertion( "up-regulation of T cell proliferation") -AnnotationAssertion( "upregulation of T cell proliferation") -AnnotationAssertion( "activation of T cell proliferation") -AnnotationAssertion( "stimulation of T cell proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042102") -AnnotationAssertion(rdfs:label "positive regulation of T cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of T cell homeostatic proliferation) - -AnnotationAssertion(Annotation( "GOC:jl") "Any process that activates or increases the rate or extent of resting T cell proliferation.") -AnnotationAssertion( "positive regulation of T lymphocyte homeostatic proliferation") -AnnotationAssertion( "positive regulation of T-cell homeostatic proliferation") -AnnotationAssertion( "positive regulation of T-lymphocyte homeostatic proliferation") -AnnotationAssertion( "positive regulation of resting T cell proliferation") -AnnotationAssertion( "up regulation of T cell homeostatic proliferation") -AnnotationAssertion( "up-regulation of T cell homeostatic proliferation") -AnnotationAssertion( "upregulation of T cell homeostatic proliferation") -AnnotationAssertion( "activation of T cell homeostatic proliferation") -AnnotationAssertion( "stimulation of T cell homeostatic proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042103") -AnnotationAssertion(rdfs:label "positive regulation of T cell homeostatic proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (T cell activation) AnnotationAssertion(Annotation( "GOC:mgi_curators") Annotation( "ISBN:0781735149") "The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.") @@ -79981,7 +24688,6 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0042110") AnnotationAssertion(rdfs:label "T cell activation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) # Class: (B cell activation) @@ -79993,45 +24699,8 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0042113") AnnotationAssertion(rdfs:label "B cell activation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (macrophage activation) - -AnnotationAssertion(Annotation( "GOC:mgi_curators") Annotation( "ISBN:0781735149") Annotation( "PMID:14506301") "A change in morphology and behavior of a macrophage resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.") -AnnotationAssertion( "macrophage polarization") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042116") -AnnotationAssertion(rdfs:label "macrophage activation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (monocyte activation) - -AnnotationAssertion(Annotation( "GOC:mgi_curators") Annotation( "ISBN:0781735149") "The change in morphology and behavior of a monocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042117") -AnnotationAssertion(rdfs:label "monocyte activation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (endothelial cell activation) - -AnnotationAssertion(Annotation( "GOC:mgi_curators") Annotation( "ISBN:0781735149") Annotation( "PMID:12851652") Annotation( "PMID:14581484") "The change in morphology and behavior of an endothelial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042118") -AnnotationAssertion(rdfs:label "endothelial cell activation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (neutrophil activation) - -AnnotationAssertion(Annotation( "GOC:mgi_curators") Annotation( "ISBN:0781735149") "The change in morphology and behavior of a neutrophil resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042119") -AnnotationAssertion(rdfs:label "neutrophil activation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (regulation of cell population proliferation) AnnotationAssertion(Annotation( "GOC:jl") "Any process that modulates the frequency, rate or extent of cell proliferation.") @@ -80040,212 +24709,11 @@ AnnotationAssertion( "regulation of cell proliferation") AnnotationAssertion( "GO:0042127") AnnotationAssertion(rdfs:label "regulation of cell population proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) DisjointClasses( ObjectSomeValuesFrom( )) -# Class: (regulation of T cell proliferation) - -AnnotationAssertion(Annotation( "GOC:jl") "Any process that modulates the frequency, rate or extent of T cell proliferation.") -AnnotationAssertion( "regulation of T lymphocyte proliferation") -AnnotationAssertion( "regulation of T-cell proliferation") -AnnotationAssertion( "regulation of T-lymphocyte proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042129") -AnnotationAssertion(rdfs:label "regulation of T cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of T cell proliferation) - -AnnotationAssertion(Annotation( "GOC:jl") "Any process that stops, prevents or reduces the rate or extent of T cell proliferation.") -AnnotationAssertion( "down regulation of T cell proliferation") -AnnotationAssertion( "down-regulation of T cell proliferation") -AnnotationAssertion( "downregulation of T cell proliferation") -AnnotationAssertion( "negative regulation of T lymphocyte proliferation") -AnnotationAssertion( "negative regulation of T-cell proliferation") -AnnotationAssertion( "negative regulation of T-lymphocyte proliferation") -AnnotationAssertion( "inhibition of T cell proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042130") -AnnotationAssertion(rdfs:label "negative regulation of T cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (neurotransmitter metabolic process) - -AnnotationAssertion(Annotation( "GOC:jl") "The chemical reactions and pathways involving neurotransmitters, any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell.") -AnnotationAssertion( ) -AnnotationAssertion( "neurotransmitter metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042133") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "neurotransmitter metabolic process") -SubClassOf( ) -SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) -DisjointClasses( ObjectSomeValuesFrom( )) - -# Class: (neurotransmitter catabolic process) - -AnnotationAssertion(Annotation( "GOC:jl") "The chemical reactions and pathways resulting in the breakdown of any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell.") -AnnotationAssertion( "neurotransmitter breakdown") -AnnotationAssertion( "neurotransmitter catabolism") -AnnotationAssertion( "neurotransmitter degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042135") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "neurotransmitter catabolic process") -SubClassOf( ) -SubClassOf( ) - -# Class: (neurotransmitter biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:jl") "The chemical reactions and pathways resulting in the formation of any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell.") -AnnotationAssertion( "neurotransmitter biosynthesis and storage") -AnnotationAssertion( "neurotransmitter biosynthetic process and storage") -AnnotationAssertion( "neurotransmitter anabolism") -AnnotationAssertion( "neurotransmitter biosynthesis") -AnnotationAssertion( "neurotransmitter formation") -AnnotationAssertion( "neurotransmitter synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042136") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "neurotransmitter biosynthetic process") -SubClassOf( ) -SubClassOf( ) - -# Class: (lipoprotein metabolic process) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving any conjugated, water-soluble protein in which the covalently attached nonprotein group consists of a lipid or lipids.") -AnnotationAssertion( "lipoprotein metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042157") -AnnotationAssertion(rdfs:label "lipoprotein metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (lipoprotein biosynthetic process) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of any conjugated, water-soluble protein in which the covalently attached nonprotein group consists of a lipid or lipids.") -AnnotationAssertion( "lipoprotein anabolism") -AnnotationAssertion( "lipoprotein biosynthesis") -AnnotationAssertion( "lipoprotein formation") -AnnotationAssertion( "lipoprotein synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042158") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "lipoprotein biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (lipoprotein catabolic process) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of any conjugated, water-soluble protein in which the covalently attached nonprotein group consists of a lipid or lipids.") -AnnotationAssertion( "lipoprotein breakdown") -AnnotationAssertion( "lipoprotein catabolism") -AnnotationAssertion( "lipoprotein degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042159") -AnnotationAssertion(rdfs:label "lipoprotein catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (neurotransmitter binding) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "Binding to a neurotransmitter, any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0042165") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "neurotransmitter binding") -SubClassOf( ) - -# Class: (acetylcholine binding) - -AnnotationAssertion(Annotation( "GOC:ai") "Binding to acetylcholine, an acetic acid ester of the organic base choline that functions as a neurotransmitter, released at the synapses of parasympathetic nerves and at neuromuscular junctions.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0042166") -AnnotationAssertion(rdfs:label "acetylcholine binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (nuclear outer membrane-endoplasmic reticulum membrane network) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:jl") Annotation( "GOC:mah") Annotation( "GOC:mcc") Annotation( "GOC:pr") Annotation( "GOC:vw") "The continuous network of membranes encompassing the nuclear outer membrane and the endoplasmic reticulum membrane.") -AnnotationAssertion(Annotation( "GOC:mah") "nuclear membrane-ER network") -AnnotationAssertion(Annotation( "GOC:mah") "nuclear membrane-endoplasmic reticulum continuum") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "NE-ER continuum") -AnnotationAssertion( "NE-ER network") -AnnotationAssertion( "nuclear envelope-ER network") -AnnotationAssertion( "nuclear envelope-endoplasmic reticulum continuum") -AnnotationAssertion(Annotation( "GOC:mah") "nuclear envelope-endoplasmic reticulum network") -AnnotationAssertion( "GO:0042175") -AnnotationAssertion(rdfs:label "nuclear outer membrane-endoplasmic reticulum membrane network") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (regulation of protein catabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "GOC:jl") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/23112"^^xsd:anyURI) -AnnotationAssertion( "kmv") -AnnotationAssertion( "2014-08-21T15:05:45Z") -AnnotationAssertion( "GO:1903362") -AnnotationAssertion( "GO:2000598") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of cellular protein breakdown") -AnnotationAssertion( "regulation of cellular protein catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of cellular protein catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of cellular protein degradation") -AnnotationAssertion( "regulation of protein breakdown") -AnnotationAssertion( "regulation of protein catabolism") -AnnotationAssertion( "regulation of protein degradation") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of cyclin breakdown") -AnnotationAssertion( "regulation of cyclin catabolic process") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of cyclin catabolism") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of cyclin degradation") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of degradation of cyclin") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042176") -AnnotationAssertion(rdfs:label "regulation of protein catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of protein catabolic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:kmv") Annotation( "GOC:obol") Annotation( "GO_REF:0000058") Annotation( "PMID:24785082") "Any process that stops, prevents or reduces the frequency, rate or extent of protein catabolic process.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/23112"^^xsd:anyURI) -AnnotationAssertion( "GO:1903363") -AnnotationAssertion( "GO:2000599") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of cellular protein breakdown") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of cellular protein catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of cellular protein catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of cellular protein degradation") -AnnotationAssertion( "down regulation of protein catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of cellular protein breakdown") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of cellular protein catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of cellular protein catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of cellular protein degradation") -AnnotationAssertion( "down-regulation of protein catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of cellular protein breakdown") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of cellular protein catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of cellular protein catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of cellular protein degradation") -AnnotationAssertion( "downregulation of protein catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of cellular protein breakdown") -AnnotationAssertion( "negative regulation of cellular protein catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of cellular protein catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of cellular protein degradation") -AnnotationAssertion( "negative regulation of protein breakdown") -AnnotationAssertion( "negative regulation of protein catabolism") -AnnotationAssertion( "negative regulation of protein degradation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of cellular protein breakdown") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of cellular protein catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of cellular protein catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of cellular protein degradation") -AnnotationAssertion( "inhibition of protein catabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042177") -AnnotationAssertion(rdfs:label "negative regulation of protein catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (cellular ketone metabolic process) AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0787650153") "The chemical reactions and pathways involving any of a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms, as carried out by individual cells. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups.") @@ -80254,7 +24722,6 @@ AnnotationAssertion( "GO:0042180") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "cellular ketone metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ) @@ -80270,65 +24737,11 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0042181") AnnotationAssertion(rdfs:label "ketone biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) -# Class: (ketone catabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways resulting in the breakdown of ketones, a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups.") -AnnotationAssertion( "ketone breakdown") -AnnotationAssertion( "ketone catabolism") -AnnotationAssertion( "ketone degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042182") -AnnotationAssertion(rdfs:label "ketone catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (formate catabolic process) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of formate, also known as methanoate, the anion HCOO- derived from methanoic (formic) acid.") -AnnotationAssertion( "formate breakdown") -AnnotationAssertion( "formate catabolism") -AnnotationAssertion( "formate degradation") -AnnotationAssertion( "formic acid catabolic process") -AnnotationAssertion( "formic acid catabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042183") -AnnotationAssertion(rdfs:label "formate catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (terpene metabolic process) - -AnnotationAssertion(Annotation( "GOC:curators") "The chemical reactions and pathways involving terpenes, any of a large group of hydrocarbons that are made up of isoprene (C5H8) units which may be cyclic, acyclic or multicyclic, saturated or unsaturated, and may contain various functional groups.") -AnnotationAssertion( "terpene metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042214") -AnnotationAssertion(rdfs:label "terpene metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cellular modified amino acid catabolic process) - -AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways resulting in the breakdown of compounds derived from amino acids, organic acids containing one or more amino substituents.") -AnnotationAssertion( "amino acid derivative catabolic process") -AnnotationAssertion( "cellular amino acid derivative breakdown") -AnnotationAssertion( "cellular amino acid derivative catabolic process") -AnnotationAssertion( "cellular amino acid derivative catabolism") -AnnotationAssertion( "cellular amino acid derivative degradation") -AnnotationAssertion(Annotation( "GOC:mah") "cellular modified amino acid breakdown") -AnnotationAssertion(Annotation( "GOC:mah") "cellular modified amino acid catabolism") -AnnotationAssertion(Annotation( "GOC:mah") "cellular modified amino acid degradation") -AnnotationAssertion(Annotation( "GOC:mah") "modified amino acid catabolic process") -AnnotationAssertion(Annotation( "GOC:mah") "modified amino acid catabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042219") -AnnotationAssertion(rdfs:label "cellular modified amino acid catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (response to chemical) AnnotationAssertion(Annotation( "GOC:jl") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus.") @@ -80344,7 +24757,6 @@ AnnotationAssertion( ) AnnotationAssertion(rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.") AnnotationAssertion(rdfs:label "response to chemical") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) # Class: (tissue regeneration) @@ -80354,72 +24766,12 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0042246") AnnotationAssertion(rdfs:label "tissue regeneration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) DisjointClasses( ObjectSomeValuesFrom( )) -# Class: (ribosome biogenesis) - -AnnotationAssertion(Annotation( "GOC:ma") Annotation( "PMID:26404467") Annotation( "Wikipedia:Ribosome_biogenesis") "A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits; includes transport to the sites of protein synthesis.") -AnnotationAssertion( "GO:0007046") -AnnotationAssertion( "ribosome biogenesis and assembly") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042254") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "ribosome biogenesis") -SubClassOf( ) - -# Class: (ribosome assembly) - -AnnotationAssertion(Annotation( "GOC:ma") Annotation( "PMID:30467428") "The aggregation, arrangement and bonding together of the mature ribosome and of its subunits.") -AnnotationAssertion( "GO:0042257") -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:vw") "ribosomal subunit assembly") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042255") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "ribosome assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (peptide binding) - -AnnotationAssertion(Annotation( "GOC:jl") "Binding to a peptide, an organic compound comprising two or more amino acids linked by peptide bonds.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0042277") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "peptide binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (purine nucleoside metabolic process) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0140512713") "The chemical reactions and pathways involving one of a family of organic molecules consisting of a purine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside).") -AnnotationAssertion( "purine metabolic process") -AnnotationAssertion( "purine metabolism") -AnnotationAssertion( "purine nucleoside metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042278") -AnnotationAssertion(rdfs:label "purine nucleoside metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (phosphate ion binding) - -AnnotationAssertion(Annotation( "GOC:jl") "Binding to a phosphate ion.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0042301") -AnnotationAssertion(rdfs:label "phosphate ion binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (molting cycle) AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0198506732") "The periodic casting off and regeneration of an outer covering of cuticle, feathers, hair, horns, skin, etc.") @@ -80430,215 +24782,6 @@ AnnotationAssertion( "molting cycle") SubClassOf( ) -# Class: (regulation of fatty acid biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "GOC:jl") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fatty acids, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils.") -AnnotationAssertion( "regulation of fatty acid anabolism") -AnnotationAssertion( "regulation of fatty acid biosynthesis") -AnnotationAssertion( "regulation of fatty acid formation") -AnnotationAssertion( "regulation of fatty acid synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042304") -AnnotationAssertion(rdfs:label "regulation of fatty acid biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of protein import into nucleus) - -AnnotationAssertion(Annotation( "GOC:jl") "Any process that modulates the frequency, rate or extent of movement of proteins from the cytoplasm to the nucleus.") -AnnotationAssertion( "regulation of protein import into cell nucleus") -AnnotationAssertion( "regulation of protein transport from cytoplasm to nucleus") -AnnotationAssertion( "regulation of protein-nucleus import") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042306") -AnnotationAssertion(rdfs:label "regulation of protein import into nucleus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of protein import into nucleus) - -AnnotationAssertion(Annotation( "GOC:jl") "Any process that activates or increases the frequency, rate or extent of movement of proteins from the cytoplasm into the nucleus.") -AnnotationAssertion( "positive regulation of protein import into cell nucleus") -AnnotationAssertion( "positive regulation of protein transport from cytoplasm to nucleus") -AnnotationAssertion( "positive regulation of protein-nucleus import") -AnnotationAssertion( "up regulation of protein import into nucleus") -AnnotationAssertion( "up-regulation of protein import into nucleus") -AnnotationAssertion( "upregulation of protein import into nucleus") -AnnotationAssertion( "activation of protein import into nucleus") -AnnotationAssertion( "stimulation of protein import into nucleus") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042307") -AnnotationAssertion(rdfs:label "positive regulation of protein import into nucleus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of protein import into nucleus) - -AnnotationAssertion(Annotation( "GOC:jl") "Any process that stops, prevents, or reduces the frequency, rate or extent of the movement of proteins from the cytoplasm into the nucleus.") -AnnotationAssertion( "down regulation of protein import into nucleus") -AnnotationAssertion( "down-regulation of protein import into nucleus") -AnnotationAssertion( "downregulation of protein import into nucleus") -AnnotationAssertion( "negative regulation of protein import into cell nucleus") -AnnotationAssertion( "negative regulation of protein transport from cytoplasm to nucleus") -AnnotationAssertion( "negative regulation of protein-nucleus import") -AnnotationAssertion( "inhibition of protein import into nucleus") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042308") -AnnotationAssertion(rdfs:label "negative regulation of protein import into nucleus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of circadian sleep/wake cycle, sleep) - -AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "GOC:jl") Annotation( "ISBN:0192800981") "Any process that stops, prevents or reduces the duration or quality of sleep, a readily reversible state of reduced awareness and metabolic activity that occurs periodically in many animals.") -AnnotationAssertion( "down regulation of circadian sleep/wake cycle, sleep") -AnnotationAssertion( "down-regulation of circadian sleep/wake cycle, sleep") -AnnotationAssertion( "downregulation of circadian sleep/wake cycle, sleep") -AnnotationAssertion( "negative regulation of sleep") -AnnotationAssertion( "inhibition of circadian sleep/wake cycle, sleep") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042321") -AnnotationAssertion(rdfs:label "negative regulation of circadian sleep/wake cycle, sleep") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of circadian sleep/wake cycle, non-REM sleep) - -AnnotationAssertion(Annotation( "GOC:jl") "Any process that stops, prevents or reduces the duration or quality of non-rapid eye movement (NREM) sleep.") -AnnotationAssertion( "down regulation of circadian sleep/wake cycle, non-REM sleep") -AnnotationAssertion( "down-regulation of circadian sleep/wake cycle, non-REM sleep") -AnnotationAssertion( "downregulation of circadian sleep/wake cycle, non-REM sleep") -AnnotationAssertion( "negative regulation of non-REM sleep") -AnnotationAssertion( "inhibition of circadian sleep/wake cycle, non-REM sleep") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042323") -AnnotationAssertion(rdfs:label "negative regulation of circadian sleep/wake cycle, non-REM sleep") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of phosphorylation) - -AnnotationAssertion(Annotation( "GOC:jl") "Any process that modulates the frequency, rate or extent of addition of phosphate groups into a molecule.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042325") -AnnotationAssertion(rdfs:label "regulation of phosphorylation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of phosphorylation) - -AnnotationAssertion(Annotation( "GOC:jl") "Any process that stops, prevents or decreases the rate of addition of phosphate groups to a molecule.") -AnnotationAssertion( "down regulation of phosphorylation") -AnnotationAssertion( "down-regulation of phosphorylation") -AnnotationAssertion( "downregulation of phosphorylation") -AnnotationAssertion( "inhibition of phosphorylation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042326") -AnnotationAssertion(rdfs:label "negative regulation of phosphorylation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of phosphorylation) - -AnnotationAssertion(Annotation( "GOC:jl") "Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to a molecule.") -AnnotationAssertion( "up regulation of phosphorylation") -AnnotationAssertion( "up-regulation of phosphorylation") -AnnotationAssertion( "upregulation of phosphorylation") -AnnotationAssertion( "activation of phosphorylation") -AnnotationAssertion( "stimulation of phosphorylation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042327") -AnnotationAssertion(rdfs:label "positive regulation of phosphorylation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (taxis) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0192801023") "The directed movement of a motile cell or organism in response to an external stimulus.") -AnnotationAssertion( "Wikipedia:Taxis") -AnnotationAssertion( "directed movement in response to stimulus") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042330") -AnnotationAssertion(rdfs:label "taxis") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cuticle development) - -AnnotationAssertion(Annotation( "ISBN:0192800825") "The chemical reactions and pathways resulting in the formation of a cuticle, the outer layer of some animals and plants, which acts to prevent water loss.") -AnnotationAssertion( "cuticle anabolism") -AnnotationAssertion( "cuticle biosynthesis") -AnnotationAssertion( "cuticle biosynthetic process") -AnnotationAssertion( "cuticle formation") -AnnotationAssertion( "cuticle synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042335") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "cuticle development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cuticle development involved in chitin-based cuticle molting cycle) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:jl") Annotation( "GOC:mtg_sensu") Annotation( "GOC:tb") "The synthesis and deposition of a chitin-based non-cellular, hardened, or membranous secretion from an epithelial sheet, occurring as part of the molting cycle. An example of this is found in Drosophila melanogaster.") -AnnotationAssertion( "cuticle anabolism during molting") -AnnotationAssertion( "cuticle biosynthetic process during molting") -AnnotationAssertion( "cuticle formation during molting") -AnnotationAssertion( "cuticle synthesis during molting") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "chitin-based cuticle development during molting") -AnnotationAssertion( "GO:0042337") -AnnotationAssertion(rdfs:label "cuticle development involved in chitin-based cuticle molting cycle") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (keratan sulfate metabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways involving keratan sulfate, a glycosaminoglycan with repeat units consisting of beta-1,4-linked D-galactopyranosyl-beta-(1,4)-N-acetyl-D-glucosamine 6-sulfate and with variable amounts of fucose, sialic acid and mannose units; keratan sulfate chains are covalently linked by a glycosidic attachment through the trisaccharide galactosyl-galactosyl-xylose to peptidyl-threonine or serine residues.") -AnnotationAssertion( "keratan sulfate metabolism") -AnnotationAssertion( "keratan sulphate metabolic process") -AnnotationAssertion( "keratan sulphate metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042339") -AnnotationAssertion(rdfs:label "keratan sulfate metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (keratan sulfate catabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways resulting in the breakdown of keratan sulfate, a glycosaminoglycan with repeat units consisting of beta-1,4-linked D-galactopyranosyl-beta-(1,4)-N-acetyl-D-glucosamine 6-sulfate and with variable amounts of fucose, sialic acid and mannose units; keratan sulfate chains are covalently linked by a glycosidic attachment through the trisaccharide galactosyl-galactosyl-xylose to peptidyl-threonine or serine residues.") -AnnotationAssertion( "keratan sulfate breakdown") -AnnotationAssertion( "keratan sulfate catabolism") -AnnotationAssertion( "keratan sulfate degradation") -AnnotationAssertion( "keratan sulphate catabolic process") -AnnotationAssertion( "keratan sulphate catabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042340") -AnnotationAssertion(rdfs:label "keratan sulfate catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (chemokine receptor binding) - -AnnotationAssertion(Annotation( "GOC:ai") "Binding to a chemokine receptor.") -AnnotationAssertion( "chemokine receptor ligand") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0042379") -AnnotationAssertion(rdfs:label "chemokine receptor binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (hemocyte differentiation) - -AnnotationAssertion(Annotation( "CL:0000387") Annotation( "GOC:jl") Annotation( "GOC:mtg_sensu") Annotation( "PMID:9550723") "The process in which a relatively unspecialized cell acquires the characteristics of a mature hemocyte. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen.") -AnnotationAssertion( "arthropod blood cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042386") -AnnotationAssertion(rdfs:label "hemocyte differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - # Class: (regulation of membrane potential) AnnotationAssertion(Annotation( "GOC:jl") Annotation( "GOC:mtg_cardio") Annotation( "GOC:tb") Annotation( "ISBN:0198506732") "Any process that modulates the establishment or extent of a membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.") @@ -80647,49 +24790,6 @@ AnnotationAssertion( "regulation of membrane potential") SubClassOf( ObjectSomeValuesFrom( )) -# Class: (cellular modified amino acid biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways resulting in the formation of compounds derived from amino acids, organic acids containing one or more amino substituents.") -AnnotationAssertion( "amino acid derivative biosynthetic process") -AnnotationAssertion( "cellular amino acid derivative anabolism") -AnnotationAssertion( "cellular amino acid derivative biosynthesis") -AnnotationAssertion( "cellular amino acid derivative biosynthetic process") -AnnotationAssertion( "cellular amino acid derivative formation") -AnnotationAssertion( "cellular amino acid derivative synthesis") -AnnotationAssertion(Annotation( "GOC:mah") "cellular modified amino acid anabolism") -AnnotationAssertion(Annotation( "GOC:mah") "cellular modified amino acid biosynthesis") -AnnotationAssertion(Annotation( "GOC:mah") "cellular modified amino acid formation") -AnnotationAssertion(Annotation( "GOC:mah") "cellular modified amino acid synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042398") -AnnotationAssertion(rdfs:label "cellular modified amino acid biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (biogenic amine biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0395825172") "The chemical reactions and pathways occurring at the level of individual cells resulting in the formation of any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters.") -AnnotationAssertion( "biogenic amine anabolism") -AnnotationAssertion( "biogenic amine biosynthesis") -AnnotationAssertion( "biogenic amine formation") -AnnotationAssertion( "biogenic amine synthesis") -AnnotationAssertion( "cellular biogenic amine biosynthetic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042401") -AnnotationAssertion(rdfs:label "biogenic amine biosynthetic process") -SubClassOf( ) -SubClassOf( ) - -# Class: (cellular biogenic amine catabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "GOC:jl") Annotation( "ISBN:0198506732") "The chemical reactions and pathways occurring at the level of individual cells resulting in the breakdown of biogenic amines, any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters.") -AnnotationAssertion( "biogenic amine breakdown") -AnnotationAssertion( "biogenic amine catabolism") -AnnotationAssertion( "biogenic amine degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042402") -AnnotationAssertion(rdfs:label "cellular biogenic amine catabolic process") -SubClassOf( ) - # Class: (thyroid hormone metabolic process) AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving any of the compounds secreted by the thyroid gland, largely thyroxine and triiodothyronine.") @@ -80701,186 +24801,6 @@ SubClassOf( ) SubClassOf( ) -# Class: (epinephrine metabolic process) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0192801023") Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving epinephrine, a hormone produced by the medulla of the adrenal glands that increases heart activity, improves the power and prolongs the action of muscles, and increases the rate and depth of breathing. It is synthesized by the methylation of norepinephrine.") -AnnotationAssertion( "adrenaline metabolic process") -AnnotationAssertion( "adrenaline metabolism") -AnnotationAssertion( "epinephrine metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042414") -AnnotationAssertion(rdfs:label "epinephrine metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (norepinephrine metabolic process) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving norepinephrine, a hormone secreted by the adrenal medulla, and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts in the central nervous system. It is also the demethylated biosynthetic precursor of epinephrine.") -AnnotationAssertion( "levarterenol metabolic process") -AnnotationAssertion( "levarterenol metabolism") -AnnotationAssertion( "noradrenaline metabolic process") -AnnotationAssertion( "noradrenaline metabolism") -AnnotationAssertion( "norepinephrine metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042415") -AnnotationAssertion(rdfs:label "norepinephrine metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (dopamine biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline.") -AnnotationAssertion( "dopamine anabolism") -AnnotationAssertion( "dopamine biosynthesis") -AnnotationAssertion( "dopamine formation") -AnnotationAssertion( "dopamine synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042416") -AnnotationAssertion(rdfs:label "dopamine biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (dopamine metabolic process) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline.") -AnnotationAssertion( "dopamine metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042417") -AnnotationAssertion(rdfs:label "dopamine metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (epinephrine biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0192801023") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of epinephrine, a hormone produced by the medulla of the adrenal glands that increases heart activity, improves the power and prolongs the action of muscles, and increases the rate and depth of breathing. It is synthesized by the methylation of norepinephrine.") -AnnotationAssertion( "adrenaline biosynthesis") -AnnotationAssertion( "adrenaline biosynthetic process") -AnnotationAssertion( "epinephrine anabolism") -AnnotationAssertion( "epinephrine biosynthesis") -AnnotationAssertion( "epinephrine formation") -AnnotationAssertion( "epinephrine synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042418") -AnnotationAssertion(rdfs:label "epinephrine biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (epinephrine catabolic process) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0192801023") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of epinephrine, a hormone produced by the medulla of the adrenal glands that increases heart activity, improves the power and prolongs the action of muscles, and increases the rate and depth of breathing. It is synthesized by the methylation of norepinephrine.") -AnnotationAssertion( "adrenaline catabolic process") -AnnotationAssertion( "adrenaline catabolism") -AnnotationAssertion( "epinephrine breakdown") -AnnotationAssertion( "epinephrine catabolism") -AnnotationAssertion( "epinephrine degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042419") -AnnotationAssertion(rdfs:label "epinephrine catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (dopamine catabolic process) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline.") -AnnotationAssertion( "dopamine breakdown") -AnnotationAssertion( "dopamine catabolism") -AnnotationAssertion( "dopamine degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042420") -AnnotationAssertion(rdfs:label "dopamine catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (norepinephrine biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of norepinephrine, a hormone secreted by the adrenal medulla, and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts in the central nervous system. It is also the demethylated biosynthetic precursor of epinephrine.") -AnnotationAssertion( "levarterenol biosynthesis") -AnnotationAssertion( "levarterenol biosynthetic process") -AnnotationAssertion( "noradrenaline biosynthesis") -AnnotationAssertion( "noradrenaline biosynthetic process") -AnnotationAssertion( "norepinephrine anabolism") -AnnotationAssertion( "norepinephrine biosynthesis") -AnnotationAssertion( "norepinephrine formation") -AnnotationAssertion( "norepinephrine synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042421") -AnnotationAssertion(rdfs:label "norepinephrine biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (norepinephrine catabolic process) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of norepinephrine, a hormone secreted by the adrenal medulla, and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts in the central nervous system. It is also the demethylated biosynthetic precursor of epinephrine.") -AnnotationAssertion( "Wikipedia:Norepinephrine#Degradation") -AnnotationAssertion( "levarterenol catabolic process") -AnnotationAssertion( "levarterenol catabolism") -AnnotationAssertion( "noradrenaline catabolic process") -AnnotationAssertion( "noradrenaline catabolism") -AnnotationAssertion( "norepinephrine breakdown") -AnnotationAssertion( "norepinephrine catabolism") -AnnotationAssertion( "norepinephrine degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042422") -AnnotationAssertion(rdfs:label "norepinephrine catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (catecholamine biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine.") -AnnotationAssertion( "Wikipedia:Catecholamines") -AnnotationAssertion( "catecholamine anabolism") -AnnotationAssertion( "catecholamine biosynthesis") -AnnotationAssertion( "catecholamine formation") -AnnotationAssertion( "catecholamine synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042423") -AnnotationAssertion(rdfs:label "catecholamine biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (catecholamine catabolic process) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine.") -AnnotationAssertion( "catecholamine breakdown") -AnnotationAssertion( "catecholamine catabolism") -AnnotationAssertion( "catecholamine degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042424") -AnnotationAssertion(rdfs:label "catecholamine catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (choline biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0192801023") "The chemical reactions and pathways resulting in the formation of choline (2-hydroxyethyltrimethylammonium), an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine.") -AnnotationAssertion( "MetaCyc:PWY-4762") -AnnotationAssertion( "choline anabolism") -AnnotationAssertion( "choline biosynthesis") -AnnotationAssertion( "choline formation") -AnnotationAssertion( "choline synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042425") -AnnotationAssertion(rdfs:label "choline biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (choline catabolic process) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0192801023") "The chemical reactions and pathways resulting in the breakdown of choline (2-hydroxyethyltrimethylammonium), an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine.") -AnnotationAssertion( "choline breakdown") -AnnotationAssertion( "choline catabolism") -AnnotationAssertion( "choline degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042426") -AnnotationAssertion(rdfs:label "choline catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (serotonin biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties.") -AnnotationAssertion( "Wikipedia:Serotonin") -AnnotationAssertion( "serotonin anabolism") -AnnotationAssertion( "serotonin biosynthesis") -AnnotationAssertion( "serotonin formation") -AnnotationAssertion( "serotonin synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042427") -AnnotationAssertion(rdfs:label "serotonin biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (serotonin metabolic process) AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties.") @@ -80888,23 +24808,11 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0042428") AnnotationAssertion(rdfs:label "serotonin metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) -# Class: (serotonin catabolic process) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties.") -AnnotationAssertion( "serotonin breakdown") -AnnotationAssertion( "serotonin catabolism") -AnnotationAssertion( "serotonin degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042429") -AnnotationAssertion(rdfs:label "serotonin catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (indole-containing compound metabolic process) AnnotationAssertion(Annotation( "GOC:jl") Annotation( "GOC:mah") "The chemical reactions and pathways involving compounds that contain an indole (2,3-benzopyrrole) skeleton.") @@ -80919,7 +24827,6 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0042430") AnnotationAssertion(rdfs:label "indole-containing compound metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ) @@ -80938,7 +24845,6 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0042435") AnnotationAssertion(rdfs:label "indole-containing compound biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ) @@ -80946,44 +24852,6 @@ SubClassOf( ) SubClassOf( ) -# Class: (indole-containing compound catabolic process) - -AnnotationAssertion(Annotation( "GOC:jl") "The chemical reactions and pathways resulting in the breakdown of compounds that contain an indole (2,3-benzopyrrole) skeleton.") -AnnotationAssertion( "indole derivative catabolic process") -AnnotationAssertion( "indole derivative catabolism") -AnnotationAssertion( "indole-containing compound breakdown") -AnnotationAssertion( "indole-containing compound catabolism") -AnnotationAssertion( "indole-containing compound degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042436") -AnnotationAssertion(rdfs:label "indole-containing compound catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (pigment metabolic process) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving pigment, any general or particular coloring matter in living organisms, e.g. melanin.") -AnnotationAssertion( "pigment metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042440") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "pigment metabolic process") -SubClassOf( ) - -# Class: (melatonin catabolic process) - -AnnotationAssertion(Annotation( "GOC:jl") "The chemical reactions and pathways resulting in the breakdown of melatonin (N-acetyl-5-methoxytryptamine).") -AnnotationAssertion( "GO:0042449") -AnnotationAssertion( "melatonin breakdown") -AnnotationAssertion( "melatonin catabolism") -AnnotationAssertion( "melatonin degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042442") -AnnotationAssertion(rdfs:label "melatonin catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - # Class: (hormone metabolic process) AnnotationAssertion(Annotation( "GOC:jl") "The chemical reactions and pathways involving any hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone.") @@ -81013,146 +24881,6 @@ AnnotationAssertion( "hormone biosynthetic process") SubClassOf( ) -# Class: (hormone catabolic process) - -AnnotationAssertion(Annotation( "GOC:jl") "The chemical reactions and pathways resulting in the breakdown of any hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone.") -AnnotationAssertion( "hormone breakdown") -AnnotationAssertion( "hormone catabolism") -AnnotationAssertion( "hormone degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042447") -AnnotationAssertion(rdfs:label "hormone catabolic process") -SubClassOf( ) -SubClassOf( ) - -# Class: (progesterone metabolic process) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "http://www.cogsci.princeton.edu/") "The chemical reactions and pathways involving progesterone, a steroid hormone produced in the ovary which prepares and maintains the uterus for pregnancy. Also found in plants.") -AnnotationAssertion( "progesterone metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042448") -AnnotationAssertion(rdfs:label "progesterone metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (purine nucleoside biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways resulting in the formation of any purine nucleoside, one of a family of organic molecules consisting of a purine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside).") -AnnotationAssertion( "purine nucleoside anabolism") -AnnotationAssertion( "purine nucleoside biosynthesis") -AnnotationAssertion( "purine nucleoside formation") -AnnotationAssertion( "purine nucleoside synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042451") -AnnotationAssertion(rdfs:label "purine nucleoside biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (ribonucleoside catabolic process) - -AnnotationAssertion(Annotation( "GOC:jl") "The chemical reactions and pathways resulting in the breakdown of any ribonucleoside, a nucleoside in which purine or pyrimidine base is linked to a ribose (beta-D-ribofuranose) molecule.") -AnnotationAssertion( "ribonucleoside breakdown") -AnnotationAssertion( "ribonucleoside catabolism") -AnnotationAssertion( "ribonucleoside degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042454") -AnnotationAssertion(rdfs:label "ribonucleoside catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (ribonucleoside biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:jl") "The chemical reactions and pathways resulting in the formation of any ribonucleoside, a nucleoside in which purine or pyrimidine base is linked to a ribose (beta-D-ribofuranose) molecule.") -AnnotationAssertion( "ribonucleoside anabolism") -AnnotationAssertion( "ribonucleoside biosynthesis") -AnnotationAssertion( "ribonucleoside formation") -AnnotationAssertion( "ribonucleoside synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042455") -AnnotationAssertion(rdfs:label "ribonucleoside biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (photoreceptor cell development) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Development of a photoreceptor, a cell that responds to incident electromagnetic radiation, particularly visible light.") -AnnotationAssertion( "GO:0046531") -AnnotationAssertion( "photoreceptor morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042461") -AnnotationAssertion(rdfs:label "photoreceptor cell development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (eye photoreceptor cell development) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0192800981") "Development of a photoreceptor, a sensory cell in the eye that reacts to the presence of light. They usually contain a pigment that undergoes a chemical change when light is absorbed, thus stimulating a nerve.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042462") -AnnotationAssertion(rdfs:label "eye photoreceptor cell development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (melanosome) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "PMID:11584301") "A tissue-specific, membrane-bounded cytoplasmic organelle within which melanin pigments are synthesized and stored. Melanosomes are synthesized in melanocyte cells.") -AnnotationAssertion( ) -AnnotationAssertion(Annotation( "GOC:kmv") ) -AnnotationAssertion( "Wikipedia:Melanosome") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0042470") -AnnotationAssertion(rdfs:label "melanosome") -SubClassOf( ) -SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "GOC:kmv") ObjectComplementOf(ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) -SubClassOf(Annotation( "GOC:kmv") ObjectSomeValuesFrom( ObjectComplementOf())) -SubClassOf( ObjectAllValuesFrom( )) -DisjointClasses( ObjectSomeValuesFrom( )) -DisjointClasses(Annotation( "GOC:kmv") ObjectSomeValuesFrom( )) - -# Class: (ear morphogenesis) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0192801023") "The process in which the anatomical structures of the ear are generated and organized. The ear is the sense organ in vertebrates that is specialized for the detection of sound, and the maintenance of balance. Includes the outer ear and middle ear, which collect and transmit sound waves; and the inner ear, which contains the organs of balance and (except in fish) hearing. Also includes the pinna, the visible part of the outer ear, present in some mammals.") -AnnotationAssertion( "hearing organ morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042471") -AnnotationAssertion(rdfs:label "ear morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (inner ear morphogenesis) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0192801023") "The process in which the anatomical structures of the inner ear are generated and organized. The inner ear is the structure in vertebrates that contains the organs of balance and hearing. It consists of soft hollow sensory structures (the membranous labyrinth) containing fluid (endolymph) surrounded by fluid (perilymph) and encased in a bony cavity (the bony labyrinth). It consists of two chambers, the sacculus and utriculus, from which arise the cochlea and semicircular canals respectively.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042472") -AnnotationAssertion(rdfs:label "inner ear morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (outer ear morphogenesis) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0192801023") "The process in which the anatomical structures of the outer ear are generated and organized. The outer ear is the part of the ear external to the tympanum (eardrum). It consists of a tube (the external auditory meatus) that directs sound waves on to the tympanum, and may also include the external pinna, which extends beyond the skull.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042473") -AnnotationAssertion(rdfs:label "outer ear morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (middle ear morphogenesis) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0192801023") "The process in which the anatomical structures of the middle ear are generated and organized. The middle ear is the air-filled cavity within the skull of vertebrates that lies between the outer ear and the inner ear. It is linked to the pharynx (and therefore to outside air) via the Eustachian tube and in mammals contains the three ear ossicles, which transmit auditory vibrations from the outer ear (via the tympanum) to the inner ear (via the oval window).") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042474") -AnnotationAssertion(rdfs:label "middle ear morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (odontogenesis of dentin-containing tooth) AnnotationAssertion(Annotation( "GOC:cjm") Annotation( "GOC:mah") Annotation( "GOC:mtg_sensu") Annotation( "PMID:10333884") Annotation( "PMID:15355794") "The process whose specific outcome is the progression of a dentin-containing tooth over time, from its formation to the mature structure. A dentin-containing tooth is a hard, bony organ borne on the jaw or other bone of a vertebrate, and is composed mainly of dentin, a dense calcified substance, covered by a layer of enamel.") @@ -81165,7 +24893,6 @@ AnnotationAssertion( "GO:0042475") AnnotationAssertion(rdfs:comment "Note that placoid scales found in the cartilaginous fishes presumably develop through the same processes, but are found on the dermis, rather than in the mouth or pharynx. See Wikipedia:Placoid_scale#Placoid_scales.") AnnotationAssertion(rdfs:label "odontogenesis of dentin-containing tooth") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectAllValuesFrom( )) @@ -81184,217 +24911,11 @@ AnnotationAssertion( "tooth development") AnnotationAssertion( "GO:0042476") AnnotationAssertion(rdfs:label "odontogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) DisjointClasses( ObjectSomeValuesFrom( )) -# Class: (regulation of eye photoreceptor cell development) - -AnnotationAssertion(Annotation( "GOC:jl") "Any process that modulates the frequency, rate or extent of eye photoreceptor development.") -AnnotationAssertion( "regulation of eye photoreceptor development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042478") -AnnotationAssertion(rdfs:label "regulation of eye photoreceptor cell development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of eye photoreceptor cell development) - -AnnotationAssertion(Annotation( "GOC:jl") "Any process that activates or increases the frequency, rate or extent of eye photoreceptor development.") -AnnotationAssertion( "positive regulation of eye photoreceptor development") -AnnotationAssertion( "up regulation of eye photoreceptor cell development") -AnnotationAssertion( "up-regulation of eye photoreceptor cell development") -AnnotationAssertion( "upregulation of eye photoreceptor cell development") -AnnotationAssertion( "activation of eye photoreceptor cell development") -AnnotationAssertion( "stimulation of eye photoreceptor cell development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042479") -AnnotationAssertion(rdfs:label "positive regulation of eye photoreceptor cell development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (negative regulation of eye photoreceptor cell development) - -AnnotationAssertion(Annotation( "GOC:jl") "Any process that stops, prevents, or reduces the frequency, rate or extent of eye photoreceptor development.") -AnnotationAssertion( "down regulation of eye photoreceptor cell development") -AnnotationAssertion( "down-regulation of eye photoreceptor cell development") -AnnotationAssertion( "downregulation of eye photoreceptor cell development") -AnnotationAssertion( "negative regulation of eye photoreceptor development") -AnnotationAssertion( "inhibition of eye photoreceptor cell development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042480") -AnnotationAssertion(rdfs:label "negative regulation of eye photoreceptor cell development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of odontogenesis) - -AnnotationAssertion(Annotation( "GOC:jl") "Any process that modulates the frequency, rate or extent of the formation and development of a tooth or teeth.") -AnnotationAssertion( "GO:0042484") -AnnotationAssertion( "regulation of tooth development") -AnnotationAssertion( "regulation of odontogenesis of calcareous or chitinous tooth") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042481") -AnnotationAssertion(rdfs:label "regulation of odontogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of odontogenesis) - -AnnotationAssertion(Annotation( "GOC:jl") "Any process that activates or increases the frequency, rate or extent of the formation and development of a tooth or teeth.") -AnnotationAssertion( "GO:0042485") -AnnotationAssertion( "positive regulation of tooth development") -AnnotationAssertion( "up regulation of odontogenesis") -AnnotationAssertion( "up-regulation of odontogenesis") -AnnotationAssertion( "upregulation of odontogenesis") -AnnotationAssertion( "activation of odontogenesis") -AnnotationAssertion( "positive regulation of odontogenesis of calcareous or chitinous tooth") -AnnotationAssertion( "stimulation of odontogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042482") -AnnotationAssertion(rdfs:label "positive regulation of odontogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of odontogenesis) - -AnnotationAssertion(Annotation( "GOC:jl") "Any process that stops, prevents, or reduces the frequency, rate or extent of the formation and development of a tooth or teeth.") -AnnotationAssertion( "GO:0042486") -AnnotationAssertion( "down regulation of odontogenesis") -AnnotationAssertion( "down-regulation of odontogenesis") -AnnotationAssertion( "downregulation of odontogenesis") -AnnotationAssertion( "negative regulation of tooth development") -AnnotationAssertion( "inhibition of odontogenesis") -AnnotationAssertion( "negative regulation of odontogenesis of calcareous or chitinous tooth") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042483") -AnnotationAssertion(rdfs:label "negative regulation of odontogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of odontogenesis of dentin-containing tooth) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "GOC:mtg_sensu") Annotation( "PMID:15355794") "Any process that modulates the frequency, rate or extent of the formation and development of teeth, the hard, bony appendages which are borne on the jaws, or on other bones in the walls of the mouth or pharynx of most vertebrates.") -AnnotationAssertion( "regulation of odontogenesis of dentine-containing teeth") -AnnotationAssertion(Annotation( "GOC:mah") "regulation of odontogenesis of dentine-containing tooth") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042487") -AnnotationAssertion(rdfs:label "regulation of odontogenesis of dentin-containing tooth") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of odontogenesis of dentin-containing tooth) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "PMID:15355794") "Any process that activates or increases the frequency, rate or extent of the formation and development of teeth, the hard, bony appendages that are borne on the jaws, or on other bones in the walls of the mouth or pharynx of most vertebrates.") -AnnotationAssertion( "activation of odontogenesis") -AnnotationAssertion( "stimulation of odontogenesis") -AnnotationAssertion( "up regulation of odontogenesis") -AnnotationAssertion( "up-regulation of odontogenesis") -AnnotationAssertion( "upregulation of odontogenesis") -AnnotationAssertion( "positive regulation of odontogenesis of dentine-containing teeth") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "positive regulation of odontogenesis of dentine-containing tooth") -AnnotationAssertion( "GO:0042488") -AnnotationAssertion(rdfs:label "positive regulation of odontogenesis of dentin-containing tooth") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of odontogenesis of dentin-containing tooth) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "GOC:mtg_sensu") Annotation( "PMID:15355794") "Any process that stops, prevents, or reduces the frequency, rate or extent of the formation and development of teeth, the hard, bony appendages which are borne on the jaws, or on other bones in the walls of the mouth or pharynx.") -AnnotationAssertion( "down regulation of odontogenesis") -AnnotationAssertion( "down-regulation of odontogenesis") -AnnotationAssertion( "downregulation of odontogenesis") -AnnotationAssertion( "inhibition of odontogenesis") -AnnotationAssertion( "negative regulation of odontogenesis") -AnnotationAssertion( "negative regulation of odontogenesis of dentine-containing teeth") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "negative regulation of odontogenesis of dentine-containing tooth") -AnnotationAssertion( "GO:0042489") -AnnotationAssertion(rdfs:label "negative regulation of odontogenesis of dentin-containing tooth") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (mechanoreceptor differentiation) - -AnnotationAssertion(Annotation( "CL:0000199") Annotation( "GOC:jl") "The process in which a relatively unspecialized cell acquires specialized features of a mechanoreceptor, a cell specialized to transduce mechanical stimuli and relay that information centrally in the nervous system.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042490") -AnnotationAssertion(rdfs:label "mechanoreceptor differentiation") -SubClassOf( ) - -# Class: (inner ear auditory receptor cell differentiation) - -AnnotationAssertion(Annotation( "CL:0000201") Annotation( "GOC:jl") "The process in which a relatively unspecialized inner cell acquires specialized features of an auditory hair cell.") -AnnotationAssertion( "auditory hair cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "auditory receptor cell differentiation") -AnnotationAssertion( "GO:0042491") -AnnotationAssertion(rdfs:comment "Note that this term refers to the mechanosensory hair cells of the inner ear.") -AnnotationAssertion(rdfs:label "inner ear auditory receptor cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (neuron maturation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:jl") "A developmental process, independent of morphogenetic (shape) change, that is required for a neuron to attain its fully functional state.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042551") -AnnotationAssertion(rdfs:label "neuron maturation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (myelination) - -AnnotationAssertion(Annotation( "GOC:dgh") Annotation( "GOC:mah") "The process in which myelin sheaths are formed and maintained around neurons. Oligodendrocytes in the brain and spinal cord and Schwann cells in the peripheral nervous system wrap axons with compact layers of their plasma membrane. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier.") -AnnotationAssertion( "Wikipedia:Myelin") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:cjm") Annotation( "HP:0003429") "myelinogenesis") -AnnotationAssertion( "GO:0042552") -AnnotationAssertion(rdfs:label "myelination") -SubClassOf( ) - -# Class: (hormone binding) - -AnnotationAssertion(Annotation( "GOC:jl") "Binding to an hormone, a naturally occurring substance secreted by specialized cells that affect the metabolism or behavior of cells possessing functional receptors for the hormone. Hormones may be produced by the same, or different, cell as express the receptor.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0042562") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "hormone binding") -SubClassOf( ) - -# Class: (immunoglobulin complex, circulating) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") "An immunoglobulin complex that is secreted into extracellular space and found in mucosal areas or other tissues or circulating in the blood or lymph. In its canonical form, a circulating immunoglobulin complex is composed of two identical heavy chains and two identical light chains, held together by disulfide bonds. Some forms of are polymers of the basic structure and contain additional components such as J-chain and the secretory component.") -AnnotationAssertion( "Wikipedia:Antibody") -AnnotationAssertion(Annotation( "GOC:add") "antibody") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0042571") -AnnotationAssertion(rdfs:comment "Note that an immunoglobulin complex has the function of antigen binding if a suitable antigen is available.") -AnnotationAssertion(rdfs:label "immunoglobulin complex, circulating") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (azurophil granule) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "PMID:17152095") "Primary lysosomal granule found in neutrophil granulocytes. Contains a wide range of hydrolytic enzymes and is released into the extracellular fluid.") -AnnotationAssertion( "primary granule") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0042582") -AnnotationAssertion(rdfs:label "azurophil granule") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (germinal vesicle) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "GOC:mtg_sensu") Annotation( "PMID:19019837") "The enlarged, fluid filled nucleus of a primary oocyte, the development of which is suspended in prophase I of the first meiotic division between embryohood and sexual maturity.") -AnnotationAssertion( "primary oocyte nucleus") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0042585") -AnnotationAssertion(rdfs:label "germinal vesicle") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - # Class: (zymogen granule) AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0198506732") "A membrane-bounded, cytoplasmic secretory granule found in enzyme-secreting cells and visible by light microscopy. Contain zymogen, an inactive enzyme precursor, often of a digestive enzyme.") @@ -81409,7 +24930,6 @@ AnnotationAssertion(Annotation( "cellular_component") AnnotationAssertion( "GO:0042589") AnnotationAssertion(rdfs:label "zymogen granule membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) @@ -81433,121 +24953,6 @@ AnnotationAssertion( "homeostatic process") SubClassOf( ) -# Class: (glucose homeostasis) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process involved in the maintenance of an internal steady state of glucose within an organism or cell.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042593") -AnnotationAssertion(rdfs:label "glucose homeostasis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (egg chorion) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0721662544") "A protective, noncellular membrane that surrounds the eggs of various animals including insects and fish.") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0042600") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "Note that this term does not refer to the extraembryonic membrane surrounding the embryo of amniote vertebrates as this is an anatomical structure and is therefore not covered by GO.") -AnnotationAssertion(rdfs:label "egg chorion") -SubClassOf( ) - -# Class: (MHC protein complex) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:jl") Annotation( "ISBN:0781735149") Annotation( "PMID:15928678") Annotation( "PMID:16153240") "A transmembrane protein complex composed of an MHC alpha chain and, in most cases, either an MHC class II beta chain or an invariant beta2-microglobin chain, and with or without a bound peptide, lipid, or polysaccharide antigen.") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0042611") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "MHC protein complex") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (MHC class II protein complex) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:jl") Annotation( "ISBN:0120781859") Annotation( "PMID:15928678") "A transmembrane protein complex composed of an MHC class II alpha and MHC class II beta chain, and with or without a bound peptide or polysaccharide antigen.") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0042613") -AnnotationAssertion(rdfs:label "MHC class II protein complex") -SubClassOf( ) - -# Class: (hair cycle) - -AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "PMID:12230507") "The cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair; one of the collection or mass of filaments growing from the skin of an animal, and forming a covering for a part of the head or for any part or the whole of the body.") -AnnotationAssertion( ) -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042633") -AnnotationAssertion(rdfs:label "hair cycle") -SubClassOf( ) -SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) -SubClassOf( ObjectAllValuesFrom( )) -DisjointClasses( ObjectSomeValuesFrom( )) - -# Class: (regulation of hair cycle) - -AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "PMID:12230507") "Any process that modulates the frequency, rate or extent of the cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042634") -AnnotationAssertion(rdfs:label "regulation of hair cycle") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of hair cycle) - -AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "PMID:12230507") "Any process that activates or increases the frequency, rate or extent of the cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair.") -AnnotationAssertion( "up regulation of hair cycle") -AnnotationAssertion( "up-regulation of hair cycle") -AnnotationAssertion( "upregulation of hair cycle") -AnnotationAssertion( "activation of hair cycle") -AnnotationAssertion( "stimulation of hair cycle") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042635") -AnnotationAssertion(rdfs:label "positive regulation of hair cycle") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of hair cycle) - -AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "PMID:12230507") "Any process that stops, prevents, or reduces the frequency, rate or extent of the cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair.") -AnnotationAssertion( "down regulation of hair cycle") -AnnotationAssertion( "down-regulation of hair cycle") -AnnotationAssertion( "downregulation of hair cycle") -AnnotationAssertion( "inhibition of hair cycle") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042636") -AnnotationAssertion(rdfs:label "negative regulation of hair cycle") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (actomyosin) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any complex of actin, myosin, and accessory proteins.") -AnnotationAssertion( "actomyosin complex") -AnnotationAssertion( "actomyosin structure") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0042641") -AnnotationAssertion(rdfs:label "actomyosin") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (retinal cone cell differentiation) - -AnnotationAssertion(Annotation( "GOC:go_curators") "The process in which a relatively unspecialized cell acquires the specialized features of a retinal cone cell.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042670") -AnnotationAssertion(rdfs:label "retinal cone cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (muscle cell differentiation) - -AnnotationAssertion(Annotation( "CL:0000187") Annotation( "GOC:go_curators") "The process in which a relatively unspecialized cell acquires specialized features of a muscle cell.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "myogenesis") -AnnotationAssertion( "GO:0042692") -AnnotationAssertion(rdfs:label "muscle cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (ovulation cycle) AnnotationAssertion(Annotation( "ISBN:0721662544") "The type of sexual cycle seen in females, often with physiologic changes in the endometrium that recur at regular intervals during the reproductive years.") @@ -81566,22 +24971,11 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:0042701") AnnotationAssertion(rdfs:label "progesterone secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (uterine wall growth) - -AnnotationAssertion(Annotation( "GOC:jl") "The regrowth of the endometrium and blood vessels in the uterus following menstruation, resulting from a rise in progesterone levels.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042702") -AnnotationAssertion(rdfs:label "uterine wall growth") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (sperm ejaculation) AnnotationAssertion(Annotation( "GOC:jl") Annotation( "http://www.cogsci.princeton.edu/~wn/") "The expulsion of seminal fluid, thick white fluid containing spermatozoa, from the male genital tract.") @@ -81592,47 +24986,12 @@ SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (defense response to bacterium) - -AnnotationAssertion(Annotation( "GOC:jl") "Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism.") -AnnotationAssertion( "GO:0009816") -AnnotationAssertion( "GO:0042830") -AnnotationAssertion( "defence response to bacteria") -AnnotationAssertion( "defence response to bacterium") -AnnotationAssertion( "defense response to bacteria") -AnnotationAssertion( "defense response to bacterium, incompatible interaction") -AnnotationAssertion( "resistance response to pathogenic bacteria") -AnnotationAssertion( "resistance response to pathogenic bacterium") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "antibacterial peptide activity") -AnnotationAssertion( "GO:0042742") -AnnotationAssertion(rdfs:label "defense response to bacterium") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (circadian sleep/wake cycle) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "http://www.sleepquest.com") "The cycle from wakefulness through an orderly succession of sleep states and stages that occurs on an approximately 24 hour rhythm.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042745") -AnnotationAssertion(rdfs:label "circadian sleep/wake cycle") -SubClassOf( ) - -# Class: (circadian sleep/wake cycle, non-REM sleep) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "http://www.sleepquest.com") "All sleep stages in the circadian sleep/wake cycle other than REM sleep. These stages are characterized by a slowing of brain waves and other physiological functions.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042748") -AnnotationAssertion(rdfs:label "circadian sleep/wake cycle, non-REM sleep") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (regulation of circadian sleep/wake cycle) AnnotationAssertion(Annotation( "GOC:jl") "Any process that modulates the frequency, rate or extent of the circadian sleep/wake cycle.") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0042749") AnnotationAssertion(rdfs:label "regulation of circadian sleep/wake cycle") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ) @@ -81643,49 +25002,8 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:0042752") AnnotationAssertion(rdfs:label "regulation of circadian rhythm") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (positive regulation of circadian rhythm) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of a circadian rhythm behavior.") -AnnotationAssertion( "up regulation of circadian rhythm") -AnnotationAssertion( "up-regulation of circadian rhythm") -AnnotationAssertion( "upregulation of circadian rhythm") -AnnotationAssertion( "activation of circadian rhythm") -AnnotationAssertion( "stimulation of circadian rhythm") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042753") -AnnotationAssertion(rdfs:label "positive regulation of circadian rhythm") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of circadian rhythm) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of a circadian rhythm behavior.") -AnnotationAssertion( "down regulation of circadian rhythm") -AnnotationAssertion( "down-regulation of circadian rhythm") -AnnotationAssertion( "downregulation of circadian rhythm") -AnnotationAssertion( "inhibition of circadian rhythm") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042754") -AnnotationAssertion(rdfs:label "negative regulation of circadian rhythm") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of sulfur metabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving sulfur, the nonmetallic element sulfur or compounds that contain sulfur.") -AnnotationAssertion( "regulation of sulfur metabolism") -AnnotationAssertion( "regulation of sulphur metabolic process") -AnnotationAssertion( "regulation of sulphur metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042762") -AnnotationAssertion(rdfs:label "regulation of sulfur metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (amide transport) AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0198506732") "The directed movement of an amide, any compound containing one, two, or three acyl groups attached to a nitrogen atom, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") @@ -81693,134 +25011,8 @@ AnnotationAssertion( "GO:0042886") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "amide transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (amide transmembrane transporter activity) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0198506732") "Enables the transfer of an amide, any compound containing one, two, or three acyl groups attached to a nitrogen atom, from one side of a membrane to the other.") -AnnotationAssertion( "amine/amide/polyamine channel activity") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0042887") -AnnotationAssertion(rdfs:label "amide transmembrane transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (glucocorticoid receptor signaling pathway) - -AnnotationAssertion(Annotation( "GOC:mah") "The series of molecular signals initiated by glucocorticoid binding to its receptor.") -AnnotationAssertion( "glucocorticoid receptor signalling pathway") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042921") -AnnotationAssertion(rdfs:label "glucocorticoid receptor signaling pathway") -SubClassOf( ) - -# Class: (neuropeptide binding) - -AnnotationAssertion(Annotation( "http://www.wormbook.org/chapters/www_neuropeptides/neuropeptides.html") "Interacting selectively and non-covalently and stoichiometrically with neuropeptides, peptides with direct synaptic effects (peptide neurotransmitters) or indirect modulatory effects on the nervous system (peptide neuromodulators).") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0042923") -AnnotationAssertion(rdfs:label "neuropeptide binding") -SubClassOf( ) - -# Class: (D-amino acid transport) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "GOC:jsg") Annotation( "GOC:mah") "The directed movement of the D-enantiomer of an amino acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042940") -AnnotationAssertion(rdfs:label "D-amino acid transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (D-amino acid transmembrane transporter activity) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "GOC:jsg") Annotation( "GOC:mah") Annotation( "GOC:mtg_transport") Annotation( "ISBN:0815340729") "Enables the transfer of D-amino acids from one side of a membrane to the other. D-amino acids are the D-enantiomers of amino acids.") -AnnotationAssertion( "D-amino acid transporter activity") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0042943") -AnnotationAssertion(rdfs:label "D-amino acid transmembrane transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (lipoprotein transport) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0198506732") "The directed movement of any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042953") -AnnotationAssertion(rdfs:label "lipoprotein transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of apoptotic process) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "GOC:mtg_apoptosis") "Any process that modulates the occurrence or rate of cell death by apoptotic process.") -AnnotationAssertion( "regulation of apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "apoptosis regulator activity") -AnnotationAssertion( "GO:0042981") -AnnotationAssertion(rdfs:comment "This term should only be used when it is not possible to determine which phase or subtype of the apoptotic process is regulated by a gene product. Whenever detailed information is available, the more granular children terms should be used.") -AnnotationAssertion(rdfs:label "regulation of apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cell projection) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "http://www.cogsci.princeton.edu/~wn/") "A prolongation or process extending from a cell, e.g. a flagellum or axon.") -AnnotationAssertion( "cell process") -AnnotationAssertion( "cellular process") -AnnotationAssertion( "cellular projection") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0042995") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "cell projection") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (regulation of Golgi to plasma membrane protein transport) - -AnnotationAssertion(Annotation( "GOC:jl") "Any process that modulates the frequency, rate or extent of the transport of proteins from the Golgi to the plasma membrane.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042996") -AnnotationAssertion(rdfs:label "regulation of Golgi to plasma membrane protein transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of Golgi to plasma membrane protein transport) - -AnnotationAssertion(Annotation( "GOC:jl") "Any process that stops, prevents, or reduces the frequency, rate or extent of the transport of proteins from the Golgi to the plasma membrane.") -AnnotationAssertion( "down regulation of Golgi to plasma membrane protein transport") -AnnotationAssertion( "down-regulation of Golgi to plasma membrane protein transport") -AnnotationAssertion( "downregulation of Golgi to plasma membrane protein transport") -AnnotationAssertion( "inhibition of Golgi to plasma membrane protein transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042997") -AnnotationAssertion(rdfs:label "negative regulation of Golgi to plasma membrane protein transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (positive regulation of Golgi to plasma membrane protein transport) - -AnnotationAssertion(Annotation( "GOC:jl") "Any process that activates or increases the frequency, rate or extent of the transport of proteins from the Golgi to the plasma membrane.") -AnnotationAssertion( "up regulation of Golgi to plasma membrane protein transport") -AnnotationAssertion( "up-regulation of Golgi to plasma membrane protein transport") -AnnotationAssertion( "upregulation of Golgi to plasma membrane protein transport") -AnnotationAssertion( "activation of Golgi to plasma membrane protein transport") -AnnotationAssertion( "stimulation of Golgi to plasma membrane protein transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042998") -AnnotationAssertion(rdfs:label "positive regulation of Golgi to plasma membrane protein transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (Golgi to plasma membrane protein transport) - -AnnotationAssertion(Annotation( "ISBN:0716731363") "The directed movement of proteins from the Golgi to the plasma membrane in transport vesicles that move from the trans-Golgi network to the plasma membrane.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0043001") -AnnotationAssertion(rdfs:label "Golgi to plasma membrane protein transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - # Class: (neuron projection) AnnotationAssertion(Annotation( "GOC:jl") Annotation( "http://www.cogsci.princeton.edu/~wn/") "A prolongation or process extending from a nerve cell, e.g. an axon or dendrite.") @@ -81835,7 +25027,6 @@ AnnotationAssertion(Annotation( "GO:0043005") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "neuron projection") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) @@ -81851,56 +25042,6 @@ SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectAllValuesFrom( )) -# Class: (camera-type eye development) - -AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "GOC:mtg_sensu") "The process whose specific outcome is the progression of the camera-type eye over time, from its formation to the mature structure. The camera-type eye is an organ of sight that receives light through an aperture and focuses it through a lens, projecting it on a photoreceptor field.") -AnnotationAssertion( ) -AnnotationAssertion( "GO:0001747") -AnnotationAssertion( "GO:0031075") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0043010") -AnnotationAssertion(rdfs:label "camera-type eye development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) -DisjointClasses( ObjectSomeValuesFrom( )) - -# Class: (myeloid dendritic cell differentiation) - -AnnotationAssertion(Annotation( "CL:0000782") Annotation( "GOC:jl") "The process in which a monocyte acquires the specialized features of a dendritic cell, an immunocompetent cell of the lymphoid and hemopoietic systems and skin.") -AnnotationAssertion( "Wikipedia:Dendritic_cell") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0043011") -AnnotationAssertion(rdfs:label "myeloid dendritic cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (ribonucleoprotein complex binding) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:go_curators") Annotation( "GOC:vk") "Binding to a complex of RNA and protein.") -AnnotationAssertion( "RNP binding") -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:vk") "protein-RNA complex binding") -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:vk") "ribonucleoprotein binding") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0043021") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "ribonucleoprotein complex binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (ribosome binding) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Binding to a ribosome.") -AnnotationAssertion( "GO:0030376") -AnnotationAssertion( "ribosome receptor activity") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0043022") -AnnotationAssertion(rdfs:label "ribosome binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - # Class: (neuronal cell body) AnnotationAssertion(Annotation( "GOC:go_curators") "The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.") @@ -81913,82 +25054,10 @@ AnnotationAssertion( ) AnnotationAssertion(rdfs:comment "Note that 'cell body' and 'cell soma' are not used in the literature for cells that lack projections, nor for some cells (e.g. yeast with mating projections) that do have projections.") AnnotationAssertion(rdfs:label "neuronal cell body") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (T cell homeostasis) - -AnnotationAssertion(Annotation( "GOC:mgi_curators") Annotation( "ISBN:0781735149") "The process of regulating the proliferation and elimination of T cells such that the total number of T cells within a whole or part of an organism is stable over time in the absence of an outside stimulus.") -AnnotationAssertion( "T lymphocyte homeostasis") -AnnotationAssertion( "T-cell homeostasis") -AnnotationAssertion( "T-lymphocyte homeostasis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0043029") -AnnotationAssertion(rdfs:comment "Note that this term represents the return of T cell levels to stable numbers following an immune response as well as the proliferation and elimination of T cells required to maintain stable numbers in the absence of an outside stimulus.") -AnnotationAssertion(rdfs:label "T cell homeostasis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of macrophage activation) - -AnnotationAssertion(Annotation( "GOC:jl") "Any process that modulates the frequency or rate of macrophage activation.") -AnnotationAssertion( "regulation of macrophage polarization") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0043030") -AnnotationAssertion(rdfs:label "regulation of macrophage activation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of macrophage activation) - -AnnotationAssertion(Annotation( "GOC:jl") "Any process that stops, prevents, or reduces the frequency, rate or extent of macrophage activation.") -AnnotationAssertion( "down regulation of macrophage activation") -AnnotationAssertion( "down-regulation of macrophage activation") -AnnotationAssertion( "downregulation of macrophage activation") -AnnotationAssertion( "negative regulation of macrophage polarization") -AnnotationAssertion( "inhibition of macrophage activation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0043031") -AnnotationAssertion(rdfs:label "negative regulation of macrophage activation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of macrophage activation) - -AnnotationAssertion(Annotation( "GOC:jl") "Any process that stimulates, induces or increases the rate of macrophage activation.") -AnnotationAssertion( "positive regulation of macrophage polarization") -AnnotationAssertion( "up regulation of macrophage activation") -AnnotationAssertion( "up-regulation of macrophage activation") -AnnotationAssertion( "upregulation of macrophage activation") -AnnotationAssertion( "activation of macrophage activation") -AnnotationAssertion( "stimulation of macrophage activation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0043032") -AnnotationAssertion(rdfs:label "positive regulation of macrophage activation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (peptide biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:jl") "The chemical reactions and pathways resulting in the formation of peptides, compounds of 2 or more (but usually less than 100) amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another. This may include the translation of a precursor protein and its subsequent processing into a functional peptide.") -AnnotationAssertion( "peptide anabolism") -AnnotationAssertion( "peptide biosynthesis") -AnnotationAssertion( "peptide formation") -AnnotationAssertion( "peptide synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0043043") -AnnotationAssertion(rdfs:label "peptide biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (otic placode formation) - -AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "PMID:12668634") "The initial developmental process that will lead to the formation of the vertebrate inner ear. The otic placode forms as a thickening of the head ectoderm adjacent to the developing hindbrain.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0043049") -AnnotationAssertion(rdfs:label "otic placode formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (extracellular structure organization) AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:dph") Annotation( "GOC:jl") Annotation( "GOC:mah") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures in the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane, and also covers the host cell environment outside an intracellular parasite.") @@ -81999,81 +25068,6 @@ AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "extracellular structure organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of apoptotic process) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "GOC:mtg_apoptosis") "Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process.") -AnnotationAssertion( "up regulation of apoptosis") -AnnotationAssertion( "up-regulation of apoptosis") -AnnotationAssertion( "upregulation of apoptosis") -AnnotationAssertion( "activation of apoptosis") -AnnotationAssertion( "positive regulation of apoptosis") -AnnotationAssertion( "stimulation of apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "pro-apoptosis") -AnnotationAssertion( "GO:0043065") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "This term should only be used when it is not possible to determine which phase or subtype of the apoptotic process is positively regulated by a gene product. Whenever detailed information is available, the more granular children terms should be used.") -AnnotationAssertion(rdfs:label "positive regulation of apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of apoptotic process) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "GOC:mtg_apoptosis") "Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.") -AnnotationAssertion( "GO:0006916") -AnnotationAssertion( "anti-apoptosis") -AnnotationAssertion( "down regulation of apoptosis") -AnnotationAssertion( "down-regulation of apoptosis") -AnnotationAssertion( "downregulation of apoptosis") -AnnotationAssertion( "inhibition of apoptosis") -AnnotationAssertion( "negative regulation of apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "apoptosis inhibitor activity") -AnnotationAssertion( "pro-survival") -AnnotationAssertion( "GO:0043066") -AnnotationAssertion(rdfs:comment "This term should only be used when it is not possible to determine which phase or subtype of the apoptotic process is negatively regulated by a gene product. Whenever detailed information is available, the more granular children terms should be used.") -AnnotationAssertion(rdfs:label "negative regulation of apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of programmed cell death) - -AnnotationAssertion(Annotation( "GOC:jl") "Any process that modulates the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes.") -AnnotationAssertion( "GO:0043070") -AnnotationAssertion( "regulation of non-apoptotic programmed cell death") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0043067") -AnnotationAssertion(rdfs:label "regulation of programmed cell death") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of programmed cell death) - -AnnotationAssertion(Annotation( "GOC:jl") "Any process that activates or increases the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes.") -AnnotationAssertion( "GO:0043071") -AnnotationAssertion( "up regulation of programmed cell death") -AnnotationAssertion( "up-regulation of programmed cell death") -AnnotationAssertion( "upregulation of programmed cell death") -AnnotationAssertion( "activation of programmed cell death") -AnnotationAssertion( "positive regulation of non-apoptotic programmed cell death") -AnnotationAssertion( "stimulation of programmed cell death") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0043068") -AnnotationAssertion(rdfs:label "positive regulation of programmed cell death") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of programmed cell death) - -AnnotationAssertion(Annotation( "GOC:jl") "Any process that stops, prevents, or reduces the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes.") -AnnotationAssertion( "GO:0043072") -AnnotationAssertion( "down regulation of programmed cell death") -AnnotationAssertion( "down-regulation of programmed cell death") -AnnotationAssertion( "downregulation of programmed cell death") -AnnotationAssertion( "inhibition of programmed cell death") -AnnotationAssertion( "negative regulation of non-apoptotic programmed cell death") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0043069") -AnnotationAssertion(rdfs:label "negative regulation of programmed cell death") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (germ cell nucleus) @@ -82082,7 +25076,6 @@ AnnotationAssertion( "cellular_component") AnnotationAssertion( "GO:0043073") AnnotationAssertion(rdfs:label "germ cell nucleus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) # Class: (penile erection) @@ -82096,83 +25089,6 @@ SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (positive regulation of catalytic activity) - -AnnotationAssertion(Annotation( "GOC:ebc") Annotation( "GOC:jl") Annotation( "GOC:tb") Annotation( "GOC:vw") "Any process that activates or increases the activity of an enzyme.") -AnnotationAssertion( "GO:0048554") -AnnotationAssertion(Annotation( "GOC:tb") "positive regulation of enzyme activity") -AnnotationAssertion( "up regulation of enzyme activity") -AnnotationAssertion( "up-regulation of enzyme activity") -AnnotationAssertion( "upregulation of enzyme activity") -AnnotationAssertion( "activation of enzyme activity") -AnnotationAssertion( "activation of metalloenzyme activity") -AnnotationAssertion( "positive regulation of metalloenzyme activity") -AnnotationAssertion( "stimulation of enzyme activity") -AnnotationAssertion( "stimulation of metalloenzyme activity") -AnnotationAssertion( "up regulation of metalloenzyme activity") -AnnotationAssertion( "up-regulation of metalloenzyme activity") -AnnotationAssertion( "upregulation of metalloenzyme activity") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0043085") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "positive regulation of catalytic activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of catalytic activity) - -AnnotationAssertion(Annotation( "GOC:ebc") Annotation( "GOC:jl") Annotation( "GOC:tb") Annotation( "GOC:vw") "Any process that stops or reduces the activity of an enzyme.") -AnnotationAssertion( "GO:0048553") -AnnotationAssertion( "down regulation of enzyme activity") -AnnotationAssertion( "down-regulation of enzyme activity") -AnnotationAssertion( "down-regulation of metalloenzyme activity") -AnnotationAssertion( "downregulation of enzyme activity") -AnnotationAssertion(Annotation( "GOC:tb") "negative regulation of enzyme activity") -AnnotationAssertion( "down regulation of metalloenzyme activity") -AnnotationAssertion( "downregulation of metalloenzyme activity") -AnnotationAssertion( "inhibition of enzyme activity") -AnnotationAssertion( "inhibition of metalloenzyme activity") -AnnotationAssertion( "negative regulation of metalloenzyme activity") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0043086") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "negative regulation of catalytic activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of vascular permeability) - -AnnotationAssertion(Annotation( "GOC:jl") "Any process that modulates the extent to which blood vessels can be pervaded by fluid.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0043114") -AnnotationAssertion(rdfs:label "regulation of vascular permeability") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (negative regulation of vascular permeability) - -AnnotationAssertion(Annotation( "GOC:jl") "Any process that reduces the extent to which blood vessels can be pervaded by fluid.") -AnnotationAssertion( "down regulation of vascular permeability") -AnnotationAssertion( "down-regulation of vascular permeability") -AnnotationAssertion( "downregulation of vascular permeability") -AnnotationAssertion( "inhibition of vascular permeability") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0043116") -AnnotationAssertion(rdfs:label "negative regulation of vascular permeability") -SubClassOf( ) - -# Class: (positive regulation of vascular permeability) - -AnnotationAssertion(Annotation( "GOC:jl") "Any process that increases the extent to which blood vessels can be pervaded by fluid.") -AnnotationAssertion( "up regulation of vascular permeability") -AnnotationAssertion( "up-regulation of vascular permeability") -AnnotationAssertion( "upregulation of vascular permeability") -AnnotationAssertion( "activation of vascular permeability") -AnnotationAssertion( "stimulation of vascular permeability") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0043117") -AnnotationAssertion(rdfs:label "positive regulation of vascular permeability") -SubClassOf( ) - # Class: (surfactant homeostasis) AnnotationAssertion(Annotation( "PMID:23708874") Annotation( "PMID:9751757") "Any process involved in the maintenance of a steady-state level of a surface-active agent that maintains the surface tension of a liquid.") @@ -82186,68 +25102,6 @@ AnnotationAssertion( "surfactant homeostasis") SubClassOf( ) -# Class: (hindgut contraction) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "GOC:mtg_muscle") Annotation( "UBERON:0001046") "A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the hindgut. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The hindgut is the posterior part of the alimentary canal, including the rectum, and the large intestine.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0043133") -AnnotationAssertion(rdfs:label "hindgut contraction") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of hindgut contraction) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "UBERON:0001046") "Any process that modulates the frequency, rate or extent of muscle contraction of the hindgut, the posterior part of the alimentary canal, including the rectum, and the large intestine.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0043134") -AnnotationAssertion(rdfs:label "regulation of hindgut contraction") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of translation by machinery localization) - -AnnotationAssertion(Annotation( "GOC:jl") "Any process in which proteins and protein complexes involved in translation are transported to, or maintained in, a specific location.") -AnnotationAssertion( "establishment and maintenance of translational machinery localization") -AnnotationAssertion( "establishment and maintenance of translational protein localization") -AnnotationAssertion(Annotation( "GOC:mah") "regulation of translation by machinery localisation") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "translational machinery localization") -AnnotationAssertion( "translational protein localization") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0043143") -AnnotationAssertion(rdfs:label "regulation of translation by machinery localization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (ion binding) - -AnnotationAssertion(Annotation( "GOC:jl") "Binding to an ion, a charged atoms or groups of atoms.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "atom binding") -AnnotationAssertion( "GO:0043167") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "ion binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (anion binding) - -AnnotationAssertion(Annotation( "GOC:jl") "Binding to an anion, a charged atom or group of atoms with a net negative charge.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0043168") -AnnotationAssertion(rdfs:label "anion binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cation binding) - -AnnotationAssertion(Annotation( "GOC:jl") "Binding to a cation, a charged atom or group of atoms with a net positive charge.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0043169") -AnnotationAssertion(rdfs:label "cation binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (macromolecule metabolic process) AnnotationAssertion(Annotation( "GOC:mah") "The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.") @@ -82262,80 +25116,6 @@ AnnotationAssertion( "GO:0043170") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "macromolecule metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (peptide catabolic process) - -AnnotationAssertion(Annotation( "GOC:jl") "The chemical reactions and pathways resulting in the breakdown of peptides, compounds of 2 or more (but usually less than 100) amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another.") -AnnotationAssertion( "peptide breakdown") -AnnotationAssertion( "peptide catabolism") -AnnotationAssertion( "peptide degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0043171") -AnnotationAssertion(rdfs:label "peptide catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (amine binding) - -AnnotationAssertion(Annotation( "GOC:jl") "Binding to an amine, a weakly basic organic compound that contains an amino or a substituted amino group.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0043176") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "amine binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (organic acid binding) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0198506732") "Binding to an organic acid, any acidic compound containing carbon in covalent linkage.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0043177") -AnnotationAssertion(rdfs:label "organic acid binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (alcohol binding) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0198506732") "Binding to an alcohol, any of a class of alkyl compounds containing a hydroxyl group.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0043178") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "alcohol binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (vascular endothelial growth factor receptor 2 binding) - -AnnotationAssertion(Annotation( "GOC:st") "Binding to a vascular endothelial growth factor receptor 2.") -AnnotationAssertion( "KDR binding") -AnnotationAssertion( "Flk-1 binding") -AnnotationAssertion( "VEGF receptor 2 binding") -AnnotationAssertion( "VEGFR 2 binding") -AnnotationAssertion( "kinase domain region binding") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0043184") -AnnotationAssertion(rdfs:label "vascular endothelial growth factor receptor 2 binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (sulfate binding) - -AnnotationAssertion(Annotation( "GOC:mlg") "Binding to sulfate, SO4(2-), a negatively charged small molecule.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0043199") -AnnotationAssertion(rdfs:label "sulfate binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (response to amino acid) - -AnnotationAssertion(Annotation( "GOC:ef") Annotation( "GOC:mlg") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups.") -AnnotationAssertion( "GO:0010237") -AnnotationAssertion(Annotation( "GOC:dos") "response to amino acid stimulus") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0043200") -AnnotationAssertion(rdfs:label "response to amino acid") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) # Class: (response to external biotic stimulus) @@ -82346,14 +25126,6 @@ AnnotationAssertion(rdfs:label "resp SubClassOf( ) SubClassOf( ) -# Class: (glycosphingolipid binding) - -AnnotationAssertion(Annotation( "GOC:jl") "Binding to glycosphingolipid, a compound with residues of sphingoid and at least one monosaccharide.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0043208") -AnnotationAssertion(rdfs:label "glycosphingolipid binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (myelin sheath) AnnotationAssertion(Annotation( "GOC:cjm") Annotation( "GOC:jl") Annotation( "NIF_Subcellular:sao593830697") Annotation( "Wikipedia:Myelin") "An electrically insulating fatty layer that surrounds the axons of many neurons. It is an outgrowth of glial cells: Schwann cells supply the myelin for peripheral neurons while oligodendrocytes supply it to those of the central nervous system.") @@ -82394,22 +25166,7 @@ AnnotationAssertion( "cellular_component") AnnotationAssertion( "GO:0043227") AnnotationAssertion(rdfs:label "membrane-bounded organelle") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -DisjointClasses( ) - -# Class: (non-membrane-bounded organelle) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane. Includes ribosomes, the cytoskeleton and chromosomes.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/21881"^^xsd:anyURI) -AnnotationAssertion( "NIF_Subcellular:sao1456184038") -AnnotationAssertion( "non-membrane-enclosed organelle") -AnnotationAssertion( "biological condensate") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0043228") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "non-membrane-bounded organelle") -SubClassOf( ) # Class: (intracellular organelle) @@ -82418,19 +25175,6 @@ AnnotationAssertion( "GO:0043229") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "intracellular organelle") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -DisjointClasses( ) - -# Class: (extracellular organelle) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "PMID:9914479") "Organized structure of distinctive morphology and function, occurring outside the cell. Includes, for example, extracellular membrane vesicles (EMVs) and the cellulosomes of anaerobic bacteria and fungi.") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0043230") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "extracellular organelle") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) # Class: (intracellular membrane-bounded organelle) @@ -82440,7 +25184,6 @@ AnnotationAssertion( "GO:0043231") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "intracellular membrane-bounded organelle") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) # Class: (intracellular non-membrane-bounded organelle) @@ -82451,160 +25194,6 @@ AnnotationAssertion( "GO:0043232") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "intracellular non-membrane-bounded organelle") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (organelle lumen) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "GOC:mah") "The internal volume enclosed by the membranes of a particular organelle; includes the volume enclosed by a single organelle membrane, e.g. endoplasmic reticulum lumen, or the volume enclosed by the innermost of the two lipid bilayers of an organelle envelope, e.g. nuclear lumen.") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0043233") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "organelle lumen") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (receptor complex) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any protein complex that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0043235") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "receptor complex") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of protein-containing complex disassembly) - -AnnotationAssertion(Annotation( "GOC:jl") "Any process that stops, prevents, or reduces the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components.") -AnnotationAssertion( "down regulation of protein complex disassembly") -AnnotationAssertion( "down-regulation of protein complex disassembly") -AnnotationAssertion( "downregulation of protein complex disassembly") -AnnotationAssertion( "inhibition of protein complex disassembly") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "negative regulation of protein complex disassembly") -AnnotationAssertion( "GO:0043242") -AnnotationAssertion(rdfs:label "negative regulation of protein-containing complex disassembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of protein-containing complex disassembly) - -AnnotationAssertion(Annotation( "GOC:jl") "Any process that activates or increases the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components.") -AnnotationAssertion( "up regulation of protein complex disassembly") -AnnotationAssertion( "up-regulation of protein complex disassembly") -AnnotationAssertion( "upregulation of protein complex disassembly") -AnnotationAssertion( "activation of protein complex disassembly") -AnnotationAssertion( "stimulation of protein complex disassembly") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "positive regulation of protein complex disassembly") -AnnotationAssertion( "GO:0043243") -AnnotationAssertion(rdfs:label "positive regulation of protein-containing complex disassembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of protein-containing complex disassembly) - -AnnotationAssertion(Annotation( "GOC:jl") "Any process that modulates the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "regulation of protein complex disassembly") -AnnotationAssertion( "GO:0043244") -AnnotationAssertion(rdfs:label "regulation of protein-containing complex disassembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (erythrocyte maturation) - -AnnotationAssertion(Annotation( "GOC:devbiol") Annotation( "GOC:jl") "A developmental process, independent of morphogenetic (shape) change, that is required for an erythrocyte to attain its fully functional state.") -AnnotationAssertion(Annotation( "CL:0000232") "RBC maturation") -AnnotationAssertion(Annotation( "CL:0000232") "red blood cell maturation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0043249") -AnnotationAssertion(rdfs:label "erythrocyte maturation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (regulation of protein-containing complex assembly) - -AnnotationAssertion(Annotation( "GOC:jl") "Any process that modulates the frequency, rate or extent of protein complex assembly.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "regulation of protein complex assembly") -AnnotationAssertion( "GO:0043254") -AnnotationAssertion(rdfs:label "regulation of protein-containing complex assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (regulation of carbohydrate biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:jl") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of carbohydrates.") -AnnotationAssertion( "regulation of carbohydrate anabolism") -AnnotationAssertion( "regulation of carbohydrate biosynthesis") -AnnotationAssertion( "regulation of carbohydrate formation") -AnnotationAssertion( "regulation of carbohydrate synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0043255") -AnnotationAssertion(rdfs:label "regulation of carbohydrate biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (extracellular non-membrane-bounded organelle) - -AnnotationAssertion(Annotation( "GOC:jl") "Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring outside the cell.") -AnnotationAssertion( "extracellular non-membrane-enclosed organelle") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0043264") -AnnotationAssertion(rdfs:label "extracellular non-membrane-bounded organelle") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of monoatomic ion transport) - -AnnotationAssertion(Annotation( "GOC:jl") "Any process that modulates the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion( "regulation of ion transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0043269") -AnnotationAssertion(rdfs:label "regulation of monoatomic ion transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (positive regulation of monoatomic ion transport) - -AnnotationAssertion(Annotation( "GOC:jl") "Any process that activates or increases the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion( "up regulation of ion transport") -AnnotationAssertion( "up-regulation of ion transport") -AnnotationAssertion( "upregulation of ion transport") -AnnotationAssertion( "activation of ion transport") -AnnotationAssertion( "stimulation of ion transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0043270") -AnnotationAssertion(rdfs:label "positive regulation of monoatomic ion transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of monoatomic ion transport) - -AnnotationAssertion(Annotation( "GOC:jl") "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion( "negative regulation of ion transport") -AnnotationAssertion( "down regulation of ion transport") -AnnotationAssertion( "down-regulation of ion transport") -AnnotationAssertion( "downregulation of ion transport") -AnnotationAssertion( "inhibition of ion transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0043271") -AnnotationAssertion(rdfs:label "negative regulation of monoatomic ion transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (response to alkaloid) - -AnnotationAssertion(Annotation( "GOC:jl") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkaloid stimulus. Alkaloids are a large group of nitrogenous substances found in naturally in plants, many of which have extracts that are pharmacologically active.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0043279") -AnnotationAssertion(rdfs:label "response to alkaloid") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (pharyngeal muscle development) - -AnnotationAssertion(Annotation( "GOC:go_curators") "The process whose specific outcome is the progression of the pharyngeal muscle over time, from its formation to the mature structure. A pharyngeal muscle is any muscle that forms part of the pharynx.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0043282") -AnnotationAssertion(rdfs:label "pharyngeal muscle development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) # Class: (contractile fiber) @@ -82628,314 +25217,6 @@ AnnotationAssertion( "apical junction complex") SubClassOf( ) -# Class: (apical junction assembly) - -AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "PMID:10854689") Annotation( "PMID:14729475") Annotation( "PMID:15196556") "The formation of an apical junction, a functional unit located near the cell apex at the points of contact between epithelial cells composed of the tight junction, the zonula adherens junction and the desmosomes, by the aggregation, arrangement and bonding together of its constituents.") -AnnotationAssertion(Annotation( "GOC:mah") "apical junction complex assembly") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0043297") -AnnotationAssertion(rdfs:label "apical junction assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (leukocyte degranulation) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GO_REF:0000022") Annotation( "ISBN:0781735149") "The regulated exocytosis of secretory granules by a leukocyte.") -AnnotationAssertion( "immune cell degranulation") -AnnotationAssertion( "immune cell granule exocytosis") -AnnotationAssertion( "leucocyte degranulation") -AnnotationAssertion( "leukocyte granule exocytosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0043299") -AnnotationAssertion(rdfs:label "leukocyte degranulation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - -# Class: (regulation of leukocyte degranulation) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") "Any process that modulates the frequency, rate, or extent of leukocyte degranulation.") -AnnotationAssertion( "regulation of immune cell degranulation") -AnnotationAssertion( "regulation of immune cell granule exocytosis") -AnnotationAssertion( "regulation of leucocyte degranulation") -AnnotationAssertion( "regulation of leukocyte granule exocytosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0043300") -AnnotationAssertion(rdfs:label "regulation of leukocyte degranulation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of leukocyte degranulation) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") "Any process that stops, prevents, or reduces the rate of leukocyte degranulation.") -AnnotationAssertion( "down regulation of leukocyte degranulation") -AnnotationAssertion( "down-regulation of leukocyte degranulation") -AnnotationAssertion( "downregulation of leukocyte degranulation") -AnnotationAssertion( "negative regulation of immune cell degranulation") -AnnotationAssertion( "negative regulation of leucocyte degranulation") -AnnotationAssertion( "inhibition of leukocyte degranulation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0043301") -AnnotationAssertion(rdfs:label "negative regulation of leukocyte degranulation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of leukocyte degranulation) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") "Any process that activates or increases the frequency, rate or extent of leukocyte degranulation.") -AnnotationAssertion( "positive regulation of immune cell degranulation") -AnnotationAssertion( "positive regulation of leucocyte degranulation") -AnnotationAssertion( "up regulation of leukocyte degranulation") -AnnotationAssertion( "up-regulation of leukocyte degranulation") -AnnotationAssertion( "upregulation of leukocyte degranulation") -AnnotationAssertion( "activation of leukocyte degranulation") -AnnotationAssertion( "stimulation of leukocyte degranulation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0043302") -AnnotationAssertion(rdfs:label "positive regulation of leukocyte degranulation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (neutrophil degranulation) - -AnnotationAssertion(Annotation( "ISBN:0781735149") "The regulated exocytosis of secretory granules containing preformed mediators such as proteases, lipases, and inflammatory mediators by a neutrophil.") -AnnotationAssertion( "neutrophil granule exocytosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "heterophil degranulation") -AnnotationAssertion( "GO:0043312") -AnnotationAssertion(rdfs:label "neutrophil degranulation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (regulation of neutrophil degranulation) - -AnnotationAssertion(Annotation( "ISBN:0781735149") "Any process that modulates the frequency, rate, or extent of neutrophil degranulation.") -AnnotationAssertion( "regulation of neutrophil granule exocytosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0043313") -AnnotationAssertion(rdfs:label "regulation of neutrophil degranulation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (negative regulation of neutrophil degranulation) - -AnnotationAssertion(Annotation( "ISBN:0781735149") "Any process that stops, prevents, or reduces the rate of neutrophil degranulation.") -AnnotationAssertion( "down regulation of neutrophil degranulation") -AnnotationAssertion( "down-regulation of neutrophil degranulation") -AnnotationAssertion( "downregulation of neutrophil degranulation") -AnnotationAssertion( "negative regulation of neutrophil granule exocytosis") -AnnotationAssertion( "inhibition of neutrophil degranulation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0043314") -AnnotationAssertion(rdfs:label "negative regulation of neutrophil degranulation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of neutrophil degranulation) - -AnnotationAssertion(Annotation( "ISBN:0781735149") "Any process that activates or increases the frequency, rate or extent of neutrophil degranulation.") -AnnotationAssertion( "positive regulation of neutrophil granule exocytosis") -AnnotationAssertion( "up regulation of neutrophil degranulation") -AnnotationAssertion( "up-regulation of neutrophil degranulation") -AnnotationAssertion( "upregulation of neutrophil degranulation") -AnnotationAssertion( "activation of neutrophil degranulation") -AnnotationAssertion( "stimulation of neutrophil degranulation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0043315") -AnnotationAssertion(rdfs:label "positive regulation of neutrophil degranulation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (pigment metabolic process involved in developmental pigmentation) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving biological pigments e.g. melanin, occurring as part of the development of an organ or organism.") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "pigment metabolic process during developmental pigmentation") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "pigment metabolism during developmental pigmentation") -AnnotationAssertion( "GO:0043324") -AnnotationAssertion(rdfs:label "pigment metabolic process involved in developmental pigmentation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (enucleate erythrocyte differentiation) - -AnnotationAssertion(Annotation( "GOC:go_curators") "The process in which a myeloid precursor cell acquires specialized features of an erythrocyte without a nucleus. An example of this process is found in Mus musculus.") -AnnotationAssertion(Annotation( "CL:0000232") "enucleate RBC differentiation") -AnnotationAssertion(Annotation( "CL:0000232") "enucleate red blood cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0043353") -AnnotationAssertion(rdfs:label "enucleate erythrocyte differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (enucleate erythrocyte maturation) - -AnnotationAssertion(Annotation( "GOC:go_curators") "A developmental process, independent of morphogenetic (shape) change, that is required for an enucleate erythrocyte to attain its fully functional state. An enucleate erythrocyte is an erythrocyte without a nucleus.") -AnnotationAssertion(Annotation( "CL:0000232") "enucleate RBC maturation") -AnnotationAssertion(Annotation( "CL:0000232") "enucleate red blood cell maturation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0043354") -AnnotationAssertion(rdfs:label "enucleate erythrocyte maturation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (nucleate erythrocyte maturation) - -AnnotationAssertion(Annotation( "GOC:devbiol") Annotation( "GOC:jl") "A developmental process, independent of morphogenetic (shape) change, that is required for a nucleate erythrocyte to attain its fully functional state. A nucleate erythrocyte is an erythrocyte with a nucleus.") -AnnotationAssertion(Annotation( "CL:0000232") "nucleate RBC maturation") -AnnotationAssertion(Annotation( "CL:0000232") "nucleate red blood cell maturation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0043362") -AnnotationAssertion(rdfs:label "nucleate erythrocyte maturation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (nucleate erythrocyte differentiation) - -AnnotationAssertion(Annotation( "GOC:jl") "The process in which a myeloid precursor cell acquires specializes features of an erythrocyte with a nucleus, as found in non-mammalian vertebrates such as birds.") -AnnotationAssertion(Annotation( "CL:0000232") "nucleate RBC differentiation") -AnnotationAssertion(Annotation( "CL:0000232") "nucleate red blood cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0043363") -AnnotationAssertion(rdfs:label "nucleate erythrocyte differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (positive regulation of DNA binding) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:jl") Annotation( "GOC:tb") "Any process that increases the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid).") -AnnotationAssertion( "up regulation of DNA binding") -AnnotationAssertion( "up-regulation of DNA binding") -AnnotationAssertion( "upregulation of DNA binding") -AnnotationAssertion( "activation of DNA binding") -AnnotationAssertion( "stimulation of DNA binding") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0043388") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "positive regulation of DNA binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of DNA binding) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:jl") Annotation( "GOC:tb") "Any process that stops or reduces the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid).") -AnnotationAssertion( "down regulation of DNA binding") -AnnotationAssertion( "down-regulation of DNA binding") -AnnotationAssertion( "downregulation of DNA binding") -AnnotationAssertion( "inhibition of DNA binding") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0043392") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "negative regulation of DNA binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of protein binding) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of protein binding.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0043393") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "regulation of protein binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (proteoglycan binding) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "Binding to a proteoglycan, any glycoprotein in which the carbohydrate units are glycosaminoglycans.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0043394") -AnnotationAssertion(rdfs:label "proteoglycan binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (steroid hormone mediated signaling pathway) - -AnnotationAssertion(Annotation( "PMID:12606724") "The series of molecular signals mediated by a steroid hormone binding to a receptor.") -AnnotationAssertion( "steroid hormone mediated signalling") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0043401") -AnnotationAssertion(rdfs:label "steroid hormone mediated signaling pathway") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (glucocorticoid mediated signaling pathway) - -AnnotationAssertion(Annotation( "PMID:15240347") "The series of molecular signals mediated by the detection of a glucocorticoid hormone.") -AnnotationAssertion( "glucocorticoid mediated signalling") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0043402") -AnnotationAssertion(rdfs:label "glucocorticoid mediated signaling pathway") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (skeletal muscle tissue regeneration) - -AnnotationAssertion(Annotation( "GOC:ef") Annotation( "GOC:mtg_muscle") Annotation( "PMID:12021255") Annotation( "PMID:16607119") "The regrowth of skeletal muscle tissue to repair injured or damaged muscle fibers in the postnatal stage.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "myofiber turnover") -AnnotationAssertion( "GO:0043403") -AnnotationAssertion(rdfs:label "skeletal muscle tissue regeneration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (macromolecule modification) - -AnnotationAssertion(Annotation( "GOC:go_curators") "The covalent alteration of one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule, resulting in a change in its properties.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0043412") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "macromolecule modification") -SubClassOf( ) - -# Class: (positive regulation of skeletal muscle tissue regeneration) - -AnnotationAssertion(Annotation( "GOC:jl") "Any process that activates or increase the rate of skeletal muscle regeneration.") -AnnotationAssertion( "up regulation of skeletal muscle regeneration") -AnnotationAssertion( "up-regulation of skeletal muscle regeneration") -AnnotationAssertion( "upregulation of skeletal muscle regeneration") -AnnotationAssertion( "activation of skeletal muscle regeneration") -AnnotationAssertion( "stimulation of skeletal muscle regeneration") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0043415") -AnnotationAssertion(rdfs:label "positive regulation of skeletal muscle tissue regeneration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of skeletal muscle tissue regeneration) - -AnnotationAssertion(Annotation( "GOC:jl") "Any process that modulates the frequency, rate or extent of skeletal muscle.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0043416") -AnnotationAssertion(rdfs:label "regulation of skeletal muscle tissue regeneration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of skeletal muscle tissue regeneration) - -AnnotationAssertion(Annotation( "GOC:jl") "Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle regeneration.") -AnnotationAssertion( "down regulation of skeletal muscle regeneration") -AnnotationAssertion( "down-regulation of skeletal muscle regeneration") -AnnotationAssertion( "downregulation of skeletal muscle regeneration") -AnnotationAssertion( "inhibition of skeletal muscle regeneration") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0043417") -AnnotationAssertion(rdfs:label "negative regulation of skeletal muscle tissue regeneration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (response to peptide hormone) - -AnnotationAssertion(Annotation( "PMID:11027914") Annotation( "PMID:15134857") Annotation( "Wikipedia:Peptide_hormone") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide hormone stimulus. A peptide hormone is any of a class of peptides that are secreted into the blood stream and have endocrine functions in living animals.") -AnnotationAssertion(Annotation( "GOC:dos") "response to peptide hormone stimulus") -AnnotationAssertion( "response to polypeptide hormone stimulus") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0043434") -AnnotationAssertion(rdfs:label "response to peptide hormone") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - # Class: (oxoacid metabolic process) AnnotationAssertion(Annotation( "Wikipedia:Oxyacid") "The chemical reactions and pathways involving any oxoacid; an oxoacid is a compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons).") @@ -82949,326 +25230,16 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0043436") AnnotationAssertion(rdfs:label "oxoacid metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (cellular alkane metabolic process) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "Wikipedia:Alkane") "The chemical reactions and pathways involving an alkane, any acyclic branched or unbranched hydrocarbon having the general formula CnH2n+2, as carried out by individual cells.") -AnnotationAssertion( "alkane metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0043446") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "cellular alkane metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (alkane biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "Wikipedia:Alkane") "The chemical reactions and pathways resulting in the formation of an alkane, any acyclic branched or unbranched hydrocarbon having the general formula CnH2n+2.") -AnnotationAssertion( "alkane anabolism") -AnnotationAssertion( "alkane biosynthesis") -AnnotationAssertion( "alkane formation") -AnnotationAssertion( "alkane synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0043447") -AnnotationAssertion(rdfs:label "alkane biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (alkane catabolic process) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "Wikipedia:Alkane") "The chemical reactions and pathways resulting in the breakdown of an alkane, any acyclic branched or unbranched hydrocarbon having the general formula CnH2n+2.") -AnnotationAssertion( "alkane breakdown") -AnnotationAssertion( "alkane catabolism") -AnnotationAssertion( "alkane degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0043448") -AnnotationAssertion(rdfs:label "alkane catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of secondary metabolic process) - -AnnotationAssertion(Annotation( "GOC:jl") "Any process that modulates the frequency, rate or extent of secondary metabolism, the chemical reactions and pathways involving compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon.") -AnnotationAssertion( "regulation of secondary metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0043455") -AnnotationAssertion(rdfs:label "regulation of secondary metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of fermentation) - -AnnotationAssertion(Annotation( "GOC:jl") "Any process that modulates the frequency, rate or extent of fermentation, the anaerobic enzymatic conversion of organic compounds, especially carbohydrates, to other compounds, especially to ethyl alcohol, resulting in energy in the form of adenosine triphosphate (ATP).") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0043465") -AnnotationAssertion(rdfs:label "regulation of fermentation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of generation of precursor metabolites and energy) - -AnnotationAssertion(Annotation( "GOC:jl") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of precursor metabolites, substances from which energy is derived, and the processes involved in the liberation of energy from these substances.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0043467") -AnnotationAssertion(rdfs:label "regulation of generation of precursor metabolites and energy") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of carbohydrate catabolic process) - -AnnotationAssertion(Annotation( "GOC:mlg") "Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of carbohydrates.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0043470") -AnnotationAssertion(rdfs:label "regulation of carbohydrate catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (pigmentation) - -AnnotationAssertion(Annotation( "GOC:jl") "The accumulation of pigment in an organism, tissue or cell, either by increased deposition or by increased number of cells.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0043473") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "pigmentation") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - -# Class: (pigment metabolic process involved in pigmentation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:jl") Annotation( "GOC:tb") "The chemical reactions and pathways involving a pigment, any general or particular coloring matter in living organisms, resulting in the deposition or aggregation of pigment in an organism, tissue or cell.") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "pigment metabolic process during pigmentation") -AnnotationAssertion( "pigment metabolism during pigmentation") -AnnotationAssertion( "GO:0043474") -AnnotationAssertion(rdfs:label "pigment metabolic process involved in pigmentation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (muscle adaptation) - -AnnotationAssertion(Annotation( "GOC:mtg_muscle") Annotation( "PMID:11181628") Annotation( "PMID:11449884") Annotation( "PMID:12605307") "A process in which muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "muscle plasticity") -AnnotationAssertion( "GO:0043500") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "muscle adaptation") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (skeletal muscle adaptation) - -AnnotationAssertion(Annotation( "GOC:mtg_muscle") Annotation( "PMID:11181628") Annotation( "PMID:11449884") Annotation( "PMID:12605307") "Any process in which skeletal muscles change their phenotypic profiles in response to altered functional demands and a variety of signals.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "skeletal muscle plasticity") -AnnotationAssertion( "GO:0043501") -AnnotationAssertion(rdfs:label "skeletal muscle adaptation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of muscle adaptation) - -AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "GOC:mtg_muscle") "Any process that modulates the frequency, rate or extent of muscle adaptation.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "regulation of muscle plasticity") -AnnotationAssertion( "GO:0043502") -AnnotationAssertion(rdfs:label "regulation of muscle adaptation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of neuron apoptotic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "GOC:mtg_apoptosis") "Any process that modulates the occurrence or rate of cell death by apoptotic process in neurons.") -AnnotationAssertion( "regulation of apoptosis of neuronal cells") -AnnotationAssertion( "regulation of apoptosis of neurons") -AnnotationAssertion( "regulation of neuron programmed cell death") -AnnotationAssertion( "regulation of neuronal cell programmed cell death") -AnnotationAssertion( "regulation of programmed cell death of neuronal cells") -AnnotationAssertion( "regulation of programmed cell death, neurons") -AnnotationAssertion( "regulation of neuron apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0043523") -AnnotationAssertion(rdfs:label "regulation of neuron apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of neuron apoptotic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "GOC:mtg_apoptosis") "Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process in neurons.") -AnnotationAssertion( "down regulation of neuron apoptosis") -AnnotationAssertion( "down-regulation of neuron apoptosis") -AnnotationAssertion( "downregulation of neuron apoptosis") -AnnotationAssertion( "negative regulation of programmed cell death, neurons") -AnnotationAssertion( "inhibition of neuron apoptosis") -AnnotationAssertion( "negative regulation of neuron apoptosis") -AnnotationAssertion( "neuron survival") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0043524") -AnnotationAssertion(rdfs:label "negative regulation of neuron apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of neuron apoptotic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "GOC:mtg_apoptosis") "Any process that activates or increases the frequency, rate or extent of cell death of neurons by apoptotic process.") -AnnotationAssertion( "positive regulation of programmed cell death, neurons") -AnnotationAssertion( "up regulation of neuron apoptosis") -AnnotationAssertion( "up-regulation of neuron apoptosis") -AnnotationAssertion( "upregulation of neuron apoptosis") -AnnotationAssertion( "activation of neuron apoptosis") -AnnotationAssertion( "positive regulation of neuron apoptosis") -AnnotationAssertion( "stimulation of neuron apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0043525") -AnnotationAssertion(rdfs:label "positive regulation of neuron apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (ADP binding) - -AnnotationAssertion(Annotation( "GOC:jl") "Binding to ADP, adenosine 5'-diphosphate.") -AnnotationAssertion( "adenosine 5'-diphosphate binding") -AnnotationAssertion( "adenosine diphosphate binding") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0043531") -AnnotationAssertion(rdfs:label "ADP binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (blood vessel endothelial cell migration) - -AnnotationAssertion(Annotation( "PMID:11166264") "The orderly movement of an endothelial cell into the extracellular matrix in order to form new blood vessels during angiogenesis.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0043534") -AnnotationAssertion(rdfs:label "blood vessel endothelial cell migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of blood vessel endothelial cell migration) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of the migration of the endothelial cells of blood vessels.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0043535") -AnnotationAssertion(rdfs:label "regulation of blood vessel endothelial cell migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of blood vessel endothelial cell migration) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of the migration of the endothelial cells of blood vessels.") -AnnotationAssertion( "up regulation of blood vessel endothelial cell migration") -AnnotationAssertion( "up-regulation of blood vessel endothelial cell migration") -AnnotationAssertion( "upregulation of blood vessel endothelial cell migration") -AnnotationAssertion( "activation of blood vessel endothelial cell migration") -AnnotationAssertion( "stimulation of blood vessel endothelial cell migration") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0043536") -AnnotationAssertion(rdfs:label "positive regulation of blood vessel endothelial cell migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of blood vessel endothelial cell migration) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of the migration of the endothelial cells of blood vessels.") -AnnotationAssertion( "down regulation of blood vessel endothelial cell migration") -AnnotationAssertion( "down-regulation of blood vessel endothelial cell migration") -AnnotationAssertion( "downregulation of blood vessel endothelial cell migration") -AnnotationAssertion( "inhibition of blood vessel endothelial cell migration") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0043537") -AnnotationAssertion(rdfs:label "negative regulation of blood vessel endothelial cell migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (endothelial cell migration) - -AnnotationAssertion(Annotation( "GOC:go_curators") "The orderly movement of an endothelial cell into the extracellular matrix to form an endothelium.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0043542") -AnnotationAssertion(rdfs:label "endothelial cell migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of kinase activity) - -AnnotationAssertion(Annotation( "GOC:bf") "Any process that modulates the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0043549") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "regulation of kinase activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (insulin binding) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "Binding to insulin, a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms.") -AnnotationAssertion( ) -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0043559") -AnnotationAssertion(rdfs:label "insulin binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) -DisjointClasses( ObjectSomeValuesFrom( )) - # Class: (regulation of respiratory gaseous exchange) AnnotationAssertion(Annotation( "GOC:jl") "Any process that modulates the frequency, rate or extent of the process of gaseous exchange between an organism and its environment.") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0043576") AnnotationAssertion(rdfs:label "regulation of respiratory gaseous exchange") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (ear development) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0192801023") "The process whose specific outcome is the progression of the ear over time, from its formation to the mature structure. The ear is the sense organ in vertebrates that is specialized for the detection of sound, and the maintenance of balance. Includes the outer ear and middle ear, which collect and transmit sound waves; and the inner ear, which contains the organs of balance and (except in fish) hearing. Also includes the pinna, the visible part of the outer ear, present in some mammals.") -AnnotationAssertion( "hearing organ development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0043583") -AnnotationAssertion(rdfs:label "ear development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (nose development) - -AnnotationAssertion(Annotation( "GOC:jl") "The process whose specific outcome is the progression of the nose over time, from its formation to the mature structure. The nose is the specialized structure of the face that serves as the organ of the sense of smell and as part of the respiratory system. Includes the nasi externus (external nose) and cavitas nasi (nasal cavity).") -AnnotationAssertion( "nasus development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0043584") -AnnotationAssertion(rdfs:label "nose development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (nose morphogenesis) - -AnnotationAssertion(Annotation( "GOC:jl") "The process in which the anatomical structures of the nose are generated and organized. The nose is the specialized structure of the face that serves as the organ of the sense of smell and as part of the respiratory system. Includes the nasi externus (external nose) and cavitas nasi (nasal cavity).") -AnnotationAssertion( "nasus morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0043585") -AnnotationAssertion(rdfs:label "nose morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (tongue development) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "UBERON:0001723") "The process whose specific outcome is the progression of the tongue over time, from its formation to the mature structure. The tongue is the movable, muscular organ on the floor of the mouth of most vertebrates, in many other mammals is the principal organ of taste, aids in the prehension of food, in swallowing, and in modifying the voice as in speech.") -AnnotationAssertion( "glossa development") -AnnotationAssertion( "lingua development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0043586") -AnnotationAssertion(rdfs:label "tongue development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (tongue morphogenesis) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "UBERON:0001723") "The process in which the anatomical structures of the tongue are generated and organized. The tongue is the movable, muscular organ on the floor of the mouth of most vertebrates, in man other mammals is the principal organ of taste, aids in the prehension of food, in swallowing, and in modifying the voice as in speech.") -AnnotationAssertion( "lingua morphogenesis") -AnnotationAssertion( "glossa morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0043587") -AnnotationAssertion(rdfs:label "tongue morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (skin development) AnnotationAssertion(Annotation( "GOC:jl") Annotation( "UBERON:0002097") "The process whose specific outcome is the progression of the skin over time, from its formation to the mature structure. The skin is the external membranous integument of an animal. In vertebrates the skin generally consists of two layers, an outer nonsensitive and nonvascular epidermis (cuticle or skarfskin) composed of cells which are constantly growing and multiplying in the deeper, and being thrown off in the superficial layers, as well as an inner vascular dermis (cutis, corium or true skin) composed mostly of connective tissue.") @@ -83278,7 +25249,6 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0043588") AnnotationAssertion(rdfs:label "skin development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) @@ -83287,16 +25257,6 @@ SubClassOf( ObjectSomeValuesFrom( ObjectSomeValuesFrom( )) DisjointClasses( ObjectSomeValuesFrom( )) -# Class: (skin morphogenesis) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "UBERON:0002097") "The process in which the anatomical structures of the skin are generated and organized. The skin is the external membranous integument of an animal. In vertebrates the skin generally consists of two layers, an outer nonsensitive and nonvascular epidermis (cuticle or skarfskin) composed of cells which are constantly growing and multiplying in the deeper, and being thrown off in the superficial layers, as well as an inner, sensitive and vascular dermis (cutis, corium or true skin) composed mostly of connective tissue.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0043589") -AnnotationAssertion(rdfs:label "skin morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (amide metabolic process) AnnotationAssertion(Annotation( "GOC:curators") "The chemical reactions and pathways involving an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group, as carried out by individual cells.") @@ -83306,7 +25266,6 @@ AnnotationAssertion( "GO:0043603") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "amide metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (amide biosynthetic process) @@ -83314,30 +25273,9 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:0043604") AnnotationAssertion(rdfs:label "amide biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) -# Class: (amide catabolic process) - -AnnotationAssertion(Annotation( "GOC:curators") "The chemical reactions and pathways resulting in the breakdown of an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group.") -AnnotationAssertion( "cellular amide catabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0043605") -AnnotationAssertion(rdfs:label "amide catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (astrocyte cell migration) - -AnnotationAssertion(Annotation( "CL:0000127") Annotation( "GOC:go_curators") "The orderly movement of an astrocyte, a class of large neuroglial (macroglial) cells in the central nervous system, the largest and most numerous neuroglial cells in the brain and spinal cord.") -AnnotationAssertion( "astrocyte migration") -AnnotationAssertion( "astrocytic glial cell migration") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0043615") -AnnotationAssertion(rdfs:label "astrocyte cell migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - # Class: (keratinocyte proliferation) AnnotationAssertion(Annotation( "CL:0000311") "The multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population. Keratinocytes are epidermal cells which synthesize keratin and undergo a characteristic change as they move upward from the basal layers of the epidermis to the cornified (horny) layer of the skin.") @@ -83345,7 +25283,6 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0043616") AnnotationAssertion(rdfs:label "keratinocyte proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) @@ -83360,36 +25297,8 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0043648") AnnotationAssertion(rdfs:label "dicarboxylic acid metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (dicarboxylic acid catabolic process) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of dicarboxylic acids, any organic acid containing two carboxyl (-COOH) groups.") -AnnotationAssertion( "dicarboxylate catabolic process") -AnnotationAssertion( "dicarboxylate catabolism") -AnnotationAssertion( "dicarboxylic acid breakdown") -AnnotationAssertion( "dicarboxylic acid catabolism") -AnnotationAssertion( "dicarboxylic acid degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0043649") -AnnotationAssertion(rdfs:label "dicarboxylic acid catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (dicarboxylic acid biosynthetic process) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of dicarboxylic acids, any organic acid containing two carboxyl (-COOH) groups.") -AnnotationAssertion( "dicarboxylate biosynthesis") -AnnotationAssertion( "dicarboxylate biosynthetic process") -AnnotationAssertion( "dicarboxylic acid anabolism") -AnnotationAssertion( "dicarboxylic acid biosynthesis") -AnnotationAssertion( "dicarboxylic acid formation") -AnnotationAssertion( "dicarboxylic acid synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0043650") -AnnotationAssertion(rdfs:label "dicarboxylic acid biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (detection of pheromone) AnnotationAssertion(Annotation( "GOC:mah") "The series of events in which a pheromone stimulus is received by a cell and converted into a molecular signal.") @@ -83399,25 +25308,6 @@ AnnotationAssertion(rdfs:label "dete SubClassOf( ) SubClassOf( ) -# Class: (ossification involved in bone maturation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mah") Annotation( "GOC:mtg_mpo") "The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone, involved in the progression of the skeleton from its formation to its mature state.") -AnnotationAssertion(Annotation( "GOC:dph") "ossification involved in skeletal development") -AnnotationAssertion(Annotation( "GO_REF:0000034") "ossification involved in bone modeling") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0043931") -AnnotationAssertion(rdfs:label "ossification involved in bone maturation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (ossification involved in bone remodeling) - -AnnotationAssertion(Annotation( "GOC:mtg_mpo") Annotation( "GO_REF:0000034") "The formation or growth of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone, involved in response to injury or other physical, physiological or environmental stress stimuli.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "ossification involved in bone remodelling") -AnnotationAssertion( "GO:0043932") -AnnotationAssertion(rdfs:label "ossification involved in bone remodeling") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (protein-containing complex organization) AnnotationAssertion(Annotation( "GOC:mah") "Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein complex.") @@ -83439,7 +25329,6 @@ AnnotationAssertion( "protein-containing complex subunit organization") AnnotationAssertion( "GO:0043933") AnnotationAssertion(rdfs:label "protein-containing complex organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (glucan metabolic process) @@ -83448,7 +25337,6 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0044042") AnnotationAssertion(rdfs:label "glucan metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (regulation of system process) @@ -83456,7 +25344,6 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:0044057") AnnotationAssertion(rdfs:label "regulation of system process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) # Class: (regulation of digestive system process) @@ -83465,39 +25352,8 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:0044058") AnnotationAssertion(rdfs:label "regulation of digestive system process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (regulation of endocrine process) - -AnnotationAssertion(Annotation( "GOC:jl") "Any process that modulates the frequency, rate or extent of an endocrine process, a process involving the secretion of or response to endocrine hormones. An endocrine hormone is a hormone released into the circulatory system.") -AnnotationAssertion( "regulation of endocrine system process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0044060") -AnnotationAssertion(rdfs:label "regulation of endocrine process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of excretion) - -AnnotationAssertion(Annotation( "GOC:jl") "Any process that modulates the frequency, rate, or extent of excretion, the elimination by an organism of the waste products that arise as a result of metabolic activity.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0044062") -AnnotationAssertion(rdfs:label "regulation of excretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of respiratory system process) - -AnnotationAssertion(Annotation( "GOC:jl") "Any process that modulates the frequency, rate or extent of a respiratory system process, an organ system process carried out by any of the organs or tissues of the respiratory system.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0044065") -AnnotationAssertion(rdfs:label "regulation of respiratory system process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - # Class: (cellular component biogenesis) AnnotationAssertion(Annotation( "GOC:jl") Annotation( "GOC:mah") "A process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component. Includes biosynthesis of constituent macromolecules, and those macromolecular modifications that are involved in synthesis or assembly of the cellular component.") @@ -83509,88 +25365,6 @@ AnnotationAssertion( "cellular component biogenesis") SubClassOf( ) -# Class: (regulation of cellular component biogenesis) - -AnnotationAssertion(Annotation( "GOC:jl") "Any process that modulates the frequency, rate or extent of cellular component biogenesis, a process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0044087") -AnnotationAssertion(rdfs:label "regulation of cellular component biogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of vacuole organization) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a vacuole.") -AnnotationAssertion(Annotation( "GOC:mah") "regulation of vacuole organisation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:mah") "regulation of vacuole biogenesis") -AnnotationAssertion( "GO:0044088") -AnnotationAssertion(rdfs:label "regulation of vacuole organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of cellular component biogenesis) - -AnnotationAssertion(Annotation( "GOC:jl") "Any process that activates or increases the frequency, rate or extent of cellular component biogenesis, a process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0044089") -AnnotationAssertion(rdfs:label "positive regulation of cellular component biogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of vacuole organization) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a vacuole.") -AnnotationAssertion(Annotation( "GOC:mah") "positive regulation of vacuole organisation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:mah") "positive regulation of vacuole biogenesis") -AnnotationAssertion( "GO:0044090") -AnnotationAssertion(rdfs:label "positive regulation of vacuole organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (membrane biogenesis) - -AnnotationAssertion(Annotation( "GOC:jl") "A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a membrane.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0044091") -AnnotationAssertion(rdfs:label "membrane biogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of molecular function) - -AnnotationAssertion(Annotation( "GO:jl") "Any process that stops or reduces the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding.") -AnnotationAssertion( "jl") -AnnotationAssertion( "2009-04-21T04:07:27Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0044092") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "negative regulation of molecular function") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (positive regulation of molecular function) - -AnnotationAssertion(Annotation( "GO:jl") "Any process that activates or increases the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding.") -AnnotationAssertion( "jl") -AnnotationAssertion( "2009-04-21T04:11:06Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0044093") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "positive regulation of molecular function") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (translation initiation ternary complex) - -AnnotationAssertion(Annotation( "GOC:jl") "A ribonucleoprotein complex that contains aminoacylated initiator methionine tRNA, GTP, and initiation factor 2 (either eIF2 in eukaryotes, or IF2 in prokaryotes). In prokaryotes, fMet-tRNA (initiator) is used rather than Met-tRNA (initiator).") -AnnotationAssertion( "jl") -AnnotationAssertion( "2009-10-22T02:38:55Z") -AnnotationAssertion( "translation initiation (ternary) complex") -AnnotationAssertion( "Met-tRNA/eIF2.GTP ternary complex") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0044207") -AnnotationAssertion(rdfs:label "translation initiation ternary complex") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (cellular metabolic process) AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways by which individual cells transform chemical substances.") @@ -83614,31 +25388,6 @@ AnnotationAssertion( "primary metabolic process") SubClassOf( ) -# Class: (cellular lipid catabolic process) - -AnnotationAssertion(Annotation( "GOC:jl") "The chemical reactions and pathways resulting in the breakdown of lipids, as carried out by individual cells.") -AnnotationAssertion( "cellular lipid breakdown") -AnnotationAssertion( "cellular lipid catabolism") -AnnotationAssertion( "cellular lipid degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0044242") -AnnotationAssertion(rdfs:label "cellular lipid catabolic process") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (cellular catabolic process) - -AnnotationAssertion(Annotation( "GOC:jl") "The chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells.") -AnnotationAssertion( "cellular breakdown") -AnnotationAssertion( "cellular catabolism") -AnnotationAssertion( "cellular degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0044248") -AnnotationAssertion(rdfs:label "cellular catabolic process") -SubClassOf( ) -SubClassOf( ) - # Class: (cellular biosynthetic process) AnnotationAssertion(Annotation( "GOC:jl") "The chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.") @@ -83652,40 +25401,6 @@ AnnotationAssertion(rdfs:label "cell SubClassOf( ) SubClassOf( ) -# Class: (cellular lipid metabolic process) - -AnnotationAssertion(Annotation( "GOC:jl") "The chemical reactions and pathways involving lipids, as carried out by individual cells.") -AnnotationAssertion( "cellular lipid metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0044255") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "cellular lipid metabolic process") -SubClassOf( ) -SubClassOf( ) - -# Class: (intestinal lipid catabolic process) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "http://www.emc.maricopa.edu/") "The chemical reactions and pathways resulting in the breakdown into fatty acids and monoglycerides of lipids in the small intestine. Lipids are broken down by lipases released by the pancreas.") -AnnotationAssertion( "intestinal lipid breakdown") -AnnotationAssertion( "intestinal lipid catabolism") -AnnotationAssertion( "intestinal lipid degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0044258") -AnnotationAssertion(rdfs:label "intestinal lipid catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cellular nitrogen compound catabolic process) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of organic and inorganic nitrogenous compounds.") -AnnotationAssertion( "nitrogen compound breakdown") -AnnotationAssertion( "nitrogen compound catabolism") -AnnotationAssertion( "nitrogen compound degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0044270") -AnnotationAssertion(rdfs:label "cellular nitrogen compound catabolic process") -SubClassOf( ) -SubClassOf( ) - # Class: (cellular nitrogen compound biosynthetic process) AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of organic and inorganic nitrogenous compounds.") @@ -83699,35 +25414,6 @@ AnnotationAssertion(rdfs:label "cell SubClassOf( ) SubClassOf( ) -# Class: (sulfur compound biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:jl") "The chemical reactions and pathways resulting in the formation of compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione.") -AnnotationAssertion( "sulfur compound anabolism") -AnnotationAssertion( "sulfur compound biosynthesis") -AnnotationAssertion( "sulfur compound formation") -AnnotationAssertion( "sulfur compound synthesis") -AnnotationAssertion( "sulfur biosynthesis") -AnnotationAssertion( "sulfur biosynthetic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0044272") -AnnotationAssertion(rdfs:label "sulfur compound biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (sulfur compound catabolic process) - -AnnotationAssertion(Annotation( "GOC:jl") "The chemical reactions and pathways resulting in the breakdown of compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione.") -AnnotationAssertion( "sulfur compound breakdown") -AnnotationAssertion( "sulfur compound catabolism") -AnnotationAssertion( "sulfur compound degradation") -AnnotationAssertion( "sulfur catabolic process") -AnnotationAssertion( "sulfur catabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0044273") -AnnotationAssertion(rdfs:label "sulfur compound catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - # Class: (small molecule metabolic process) AnnotationAssertion(Annotation( "GOC:curators") Annotation( "GOC:pde") Annotation( "GOC:vw") "The chemical reactions and pathways involving small molecules, any low molecular weight, monomeric, non-encoded molecule.") @@ -83743,19 +25429,6 @@ AnnotationAssertion(rdfs:comment "Sm AnnotationAssertion(rdfs:label "small molecule metabolic process") SubClassOf( ) -# Class: (small molecule catabolic process) - -AnnotationAssertion(Annotation( "GOC:curators") Annotation( "GOC:vw") "The chemical reactions and pathways resulting in the breakdown of small molecules, any low molecular weight, monomeric, non-encoded molecule.") -AnnotationAssertion( "jl") -AnnotationAssertion( "2010-01-26T12:06:10Z") -AnnotationAssertion( "small molecule catabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0044282") -AnnotationAssertion(rdfs:comment "Small molecules in GO include monosaccharides but exclude disaccharides and polysaccharides.") -AnnotationAssertion(rdfs:label "small molecule catabolic process") -SubClassOf( ) -SubClassOf( ) - # Class: (small molecule biosynthetic process) AnnotationAssertion(Annotation( "GOC:curators") Annotation( "GOC:pde") Annotation( "GOC:vw") "The chemical reactions and pathways resulting in the formation of small molecules, any low molecular weight, monomeric, non-encoded molecule.") @@ -83790,56 +25463,6 @@ SubClassOf( ObjectSomeValuesFrom( ObjectSomeValuesFrom( ObjectComplementOf())) DisjointClasses( ObjectSomeValuesFrom( )) -# Class: (dentate gyrus mossy fiber) - -AnnotationAssertion(Annotation( "NIF_Subcellular:nlx_subcell_20090601") Annotation( "PMID:17765709") "Distinctive, unmyelinated axons produced by dentate gyrus granule cells.") -AnnotationAssertion( "jl") -AnnotationAssertion( "2010-02-05T11:23:55Z") -AnnotationAssertion( "granule cell axon") -AnnotationAssertion( "NIF_Subcellular:nlx_subcell_20090601") -AnnotationAssertion( "dentate gyrus mossy fibre") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0044302") -AnnotationAssertion(rdfs:label "dentate gyrus mossy fiber") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (type B pancreatic cell proliferation) - -AnnotationAssertion(Annotation( "GOC:jl") Annotation( "GOC:yaf") "The multiplication or reproduction of pancreatic B cells, resulting in the expansion of an pancreatic B cell population. Pancreatic B cell are cells of the pancreas that secrete insulin.") -AnnotationAssertion( "jl") -AnnotationAssertion( "2010-08-25T01:44:51Z") -AnnotationAssertion(Annotation( "GOC:mah") "pancreatic B cell proliferation") -AnnotationAssertion( "pancreatic beta cell proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0044342") -AnnotationAssertion(rdfs:label "type B pancreatic cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (fibroblast apoptotic process) - -AnnotationAssertion(Annotation( "CL:0000057") Annotation( "GOC:jl") Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:yaf") "Any apoptotic process in a fibroblast, a connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules.") -AnnotationAssertion( "jl") -AnnotationAssertion( "2010-09-23T11:33:38Z") -AnnotationAssertion( "fibroblast apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0044346") -AnnotationAssertion(rdfs:label "fibroblast apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (protein localization to cytoskeleton) - -AnnotationAssertion(Annotation( "GOC:jl") "A process in which a protein is transported to, or maintained in, a location within the cytoskeleton.") -AnnotationAssertion( "jl") -AnnotationAssertion( "2011-12-13T11:43:24Z") -AnnotationAssertion(Annotation( "GOC:mah") "protein localisation to cytoskeleton") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0044380") -AnnotationAssertion(rdfs:label "protein localization to cytoskeleton") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (biological process involved in interspecies interaction between organisms) AnnotationAssertion(Annotation( "GOC:cc") "Any process evolved to enable an interaction with an organism of a different species.") @@ -83860,57 +25483,6 @@ SubClassOf( ObjectComplementOf(Object SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) DisjointClasses( ObjectSomeValuesFrom( )) -# Class: (motile cilium assembly) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:cilia") Annotation( "GOC:krc") Annotation( "GO_REF:0000079") Annotation( "PMID:19776033") Annotation( "PMID:21129373") Annotation( "ZFIN:dsf") "The aggregation, arrangement and bonding together of a set of components to form a motile cilium.") -AnnotationAssertion( "krc") -AnnotationAssertion( "2015-02-06T17:23:23Z") -AnnotationAssertion( "GO:1903887") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "motile primary cilia assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "motile primary cilia formation") -AnnotationAssertion( "motile primary cilium assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "motile primary cilium formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "nodal cilium assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "nodal cilium formation") -AnnotationAssertion( "GO:0044458") -AnnotationAssertion(rdfs:label "motile cilium assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (secondary metabolite biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:jl") "The chemical reactions and pathways resulting in the formation of secondary metabolites, the compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon.") -AnnotationAssertion( "jl") -AnnotationAssertion( "2012-03-29T01:55:18Z") -AnnotationAssertion( "secondary metabolite biosynthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0044550") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "secondary metabolite biosynthetic process") -SubClassOf( ) -SubClassOf( ) - -# Class: (dendritic cell proliferation) - -AnnotationAssertion(Annotation( "CL:0000451") Annotation( "PMID:18469816") "The expansion of a dendritic cell population by cell division. A dendritic cell is a cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation.") -AnnotationAssertion( "jl") -AnnotationAssertion( "2012-04-05T04:31:39Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0044565") -AnnotationAssertion(rdfs:label "dendritic cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (chondrocyte activation) - -AnnotationAssertion(Annotation( "CL:0000138") Annotation( "GOC:jl") "A change in the morphology or behavior of a chondrocyte resulting from exposure to an activating factor such as a cellular or soluble ligand. A chondrocyte is a polymorphic cell that forms cartilage.") -AnnotationAssertion( "jl") -AnnotationAssertion( "2012-04-05T04:45:38Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0044566") -AnnotationAssertion(rdfs:label "chondrocyte activation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - # Class: (multi-organism reproductive process) AnnotationAssertion(Annotation( "GOC:jl") "A biological process that directly contributes to the process of producing new individuals, involving another organism.") @@ -83933,33 +25505,6 @@ AnnotationAssertion( "multi-multicellular organism process") SubClassOf( ) -# Class: (protein transmembrane import into intracellular organelle) - -AnnotationAssertion(Annotation( "GOC:jl") "The directed movement of proteins into an intracellular organelle, across a membrane.") -AnnotationAssertion( "jl") -AnnotationAssertion( "2012-11-07T15:37:36Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0044743") -AnnotationAssertion(rdfs:label "protein transmembrane import into intracellular organelle") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (cilium organization) - -AnnotationAssertion(Annotation( "GOC:cilia") Annotation( "GOC:jl") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole.") -AnnotationAssertion( "jl") -AnnotationAssertion( "2013-03-27T15:09:58Z") -AnnotationAssertion( "microtubule-based flagellum organization") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0044782") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "Note that we deem cilium and microtubule-based flagellum to be equivalent.") -AnnotationAssertion(rdfs:label "cilium organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - # Class: (biological phase) AnnotationAssertion(Annotation( "GOC:jl") "A distinct period or stage in a biological process or cycle.") @@ -83977,107 +25522,6 @@ DisjointClasses( ) DisjointClasses( ) -# Class: (lipoprotein localization) - -AnnotationAssertion(Annotation( "GOC:jl") "Any process in which a lipoprotein is transported to, or maintained in, a specific location.") -AnnotationAssertion( "jl") -AnnotationAssertion( "2014-11-25T16:27:06Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0044872") -AnnotationAssertion(rdfs:label "lipoprotein localization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (lipoprotein localization to membrane) - -AnnotationAssertion(Annotation( "GOC:jl") "A process in which a lipoprotein is transported to, or maintained in, a specific location in a membrane.") -AnnotationAssertion( "jl") -AnnotationAssertion( "2014-11-25T16:28:43Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0044873") -AnnotationAssertion(rdfs:label "lipoprotein localization to membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (lipoprotein localization to outer membrane) - -AnnotationAssertion(Annotation( "GOC:jl") "A process in which a lipoprotein is transported to, or maintained in, a specific location in an outer membrane.") -AnnotationAssertion( "jl") -AnnotationAssertion( "2014-11-25T16:30:30Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0044874") -AnnotationAssertion(rdfs:label "lipoprotein localization to outer membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (protein-containing complex binding) - -AnnotationAssertion(Annotation( "GOC:jl") "Binding to a macromolecular complex.") -AnnotationAssertion( "jl") -AnnotationAssertion( "2014-12-16T11:38:58Z") -AnnotationAssertion( "GO:0032403") -AnnotationAssertion( "protein complex binding") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "macromolecular complex binding") -AnnotationAssertion( "GO:0044877") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "protein-containing complex binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (chitosome) - -AnnotationAssertion(Annotation( "ISBN:0198506732") Annotation( "PMID:8970154") "An intracellular membrane-bounded particle found in fungi and containing chitin synthase; it synthesizes chitin microfibrils. Chitin synthase activity exists in chitosomes and they are proposed to act as a reservoir for regulated transport of chitin synthase enzymes to the division septum.") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0045009") -AnnotationAssertion(rdfs:label "chitosome") -SubClassOf( ) - -# Class: (plasma membrane fusion) - -AnnotationAssertion(Annotation( "GOC:elh") Annotation( "GOC:mtg_muscle") "The joining of the lipid bilayer membrane that surround a cell with that of another cell, producing a single cell.") -AnnotationAssertion( "GO:0006947") -AnnotationAssertion( "cell fusion") -AnnotationAssertion( "cell-cell fusion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045026") -AnnotationAssertion(rdfs:label "plasma membrane fusion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (G protein-coupled purinergic nucleotide receptor activity) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "PMID:9755289") "Combining with a purine nucleotide and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.") -AnnotationAssertion( "G protein coupled purinergic nucleotide receptor activity") -AnnotationAssertion( "G-protein coupled purinergic nucleotide receptor activity") -AnnotationAssertion( "purinergic nucleotide receptor activity, G protein coupled") -AnnotationAssertion(Annotation( "GOC:bf") "purinergic nucleotide receptor activity, G-protein coupled") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "P2Y") -AnnotationAssertion(Annotation( "PMID:9755289") "P2Y receptor") -AnnotationAssertion( "GO:0045028") -AnnotationAssertion(rdfs:label "G protein-coupled purinergic nucleotide receptor activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (G protein-coupled ATP receptor activity) - -AnnotationAssertion(Annotation( "GOC:mah") "Combining with ATP and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.") -AnnotationAssertion( "ATP-activated nucleotide receptor activity") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "ATP-activated adenosine receptor activity") -AnnotationAssertion( "GO:0045031") -AnnotationAssertion(rdfs:label "G protein-coupled ATP receptor activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulated exocytosis) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "ISBN:0716731363") "A process of exocytosis in which soluble proteins and other substances are initially stored in secretory vesicles for later release. It is found mainly in cells that are specialized for secreting products such as hormones, neurotransmitters, or digestive enzymes rapidly on demand.") -AnnotationAssertion( "regulated secretory pathway") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045055") -AnnotationAssertion(rdfs:label "regulated exocytosis") -SubClassOf( ) - # Class: (T cell selection) AnnotationAssertion(Annotation( "ISBN:0781735149") Annotation( "PMID:12414722") "The process in which T cells that express T cell receptors that are restricted by self MHC protein complexes and tolerant to self antigens are selected for further maturation.") @@ -84102,44 +25546,6 @@ AnnotationAssertion( "keratin filament") SubClassOf( ) -# Class: (intermediate filament-based process) - -AnnotationAssertion(Annotation( "GOC:ai") "Any cellular process that depends upon or alters the intermediate filament cytoskeleton, that part of the cytoskeleton comprising intermediate filaments and their associated proteins.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045103") -AnnotationAssertion(rdfs:label "intermediate filament-based process") -SubClassOf( ) - -# Class: (intermediate filament cytoskeleton organization) - -AnnotationAssertion(Annotation( "GOC:ai") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising intermediate filaments and their associated proteins.") -AnnotationAssertion( "intermediate filament cytoskeleton organisation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:mah") "intermediate filament cytoskeleton organization and biogenesis") -AnnotationAssertion( "GO:0045104") -AnnotationAssertion(rdfs:label "intermediate filament cytoskeleton organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (intermediate filament organization) - -AnnotationAssertion(Annotation( "GOC:ai") "Control of the spatial distribution of intermediate filaments; includes organizing filaments into meshworks, bundles, or other structures, as by cross-linking.") -AnnotationAssertion( "intermediate filament organisation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045109") -AnnotationAssertion(rdfs:label "intermediate filament organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (intermediate filament bundle assembly) - -AnnotationAssertion(Annotation( "ISBN:0716731363") "The formation of the bundles of intermediate filaments. Intermediate filament-associated proteins (IFAPs) cross-link intermediate filaments with one another, forming a bundle or a network, and with other cell structures, including the plasma membrane. The organization of intermediate filaments and their supportive function in various cells types depends in large part on their linkage to other cell structures via IFAPs.") -AnnotationAssertion( "tonofilament assembly") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045110") -AnnotationAssertion(rdfs:label "intermediate filament bundle assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (intermediate filament cytoskeleton) AnnotationAssertion(Annotation( "ISBN:0716731363") "Cytoskeletal structure made from intermediate filaments, typically organized in the cytosol as an extended system that stretches from the nuclear envelope to the plasma membrane. Some intermediate filaments run parallel to the cell surface, while others traverse the cytosol; together they form an internal framework that helps support the shape and resilience of the cell.") @@ -84148,43 +25554,6 @@ AnnotationAssertion( "intermediate filament cytoskeleton") SubClassOf( ) -# Class: (azole transmembrane transport) - -AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:3527307206") Annotation( "Wikipedia:Azole") "The directed movement of azoles, heterocyclic compounds found in many biologically important substances, across a lipid bilayer, across a membrane.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "azole transport") -AnnotationAssertion( "GO:0045117") -AnnotationAssertion(rdfs:label "azole transmembrane transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (pronucleus) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "The nucleus of either the ovum or the spermatozoon following fertilization. Thus, in the fertilized ovum, there are two pronuclei, one originating from the ovum, the other from the spermatozoon that brought about fertilization; they approach each other, but do not fuse until just before the first cleavage, when each pronucleus loses its membrane to release its contents.") -AnnotationAssertion( "Wikipedia:Pronucleus") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0045120") -AnnotationAssertion(rdfs:label "pronucleus") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - -# Class: (regulation of bone resorption) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of bone tissue loss (resorption).") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045124") -AnnotationAssertion(rdfs:label "regulation of bone resorption") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (meiotic chromosome segregation) - -AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:mah") "The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets during M phase of the meiotic cell cycle.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045132") -AnnotationAssertion(rdfs:label "meiotic chromosome segregation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (development of primary sexual characteristics) AnnotationAssertion(Annotation( "GOC:ai") "The process whose specific outcome is the progression of the primary sexual characteristics over time, from their formation to the mature structures. The primary sexual characteristics are the testes in males and the ovaries in females and they develop in response to sex hormone secretion.") @@ -84195,43 +25564,6 @@ SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (meiotic sister chromatid segregation) - -AnnotationAssertion(Annotation( "GOC:ai") Annotation( "ISBN:0815316194") "The cell cycle process in which sister chromatids are organized and then physically separated and randomly apportioned to two sets during the second division of the meiotic cell cycle.") -AnnotationAssertion( "meiosis II, chromosome segregation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045144") -AnnotationAssertion(rdfs:label "meiotic sister chromatid segregation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (cell fate commitment) - -AnnotationAssertion(Annotation( "ISBN:0716731185") "The cellular developmental process by which a cell establishes the intrinsic character of a cell or tissue region irreversibly committing it to a particular fate.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/24390"^^xsd:anyURI) -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045165") -AnnotationAssertion(rdfs:comment "Note that this term was 'cell fate determination' but the term name was changed to better match its existing definition and the child term 'cell fate determination; GO:0001709' was also created.") -AnnotationAssertion(rdfs:label "cell fate commitment") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cell-cell signaling involved in cell fate commitment) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:go_curators") Annotation( "GOC:tb") "Signaling at long or short range between cells that results in the commitment of a cell to a certain fate.") -AnnotationAssertion( "cell fate commitment, cell-cell signaling") -AnnotationAssertion( "cell fate commitment, cell-cell signalling") -AnnotationAssertion( "cell-cell signaling during in cell fate commitment") -AnnotationAssertion( "cell-cell signaling resulting in cell fate commitment") -AnnotationAssertion( "cell-cell signalling during cell fate commitment") -AnnotationAssertion( "cell-cell signalling resulting in cell fate commitment") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "cell-cell signalling involved in cell fate specification") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045168") -AnnotationAssertion(rdfs:label "cell-cell signaling involved in cell fate commitment") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (establishment of protein localization) AnnotationAssertion(Annotation( "GOC:bf") "The directed movement of a protein to a specific location.") @@ -84241,22 +25573,8 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0045184") AnnotationAssertion(rdfs:label "establishment of protein localization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (maintenance of protein location) - -AnnotationAssertion(Annotation( "GOC:bf") "Any process in which a protein is maintained in a location and prevented from moving elsewhere. These include sequestration, stabilization to prevent transport elsewhere and the active retrieval of proteins that do move away.") -AnnotationAssertion( "active protein retrieval") -AnnotationAssertion( "protein retention") -AnnotationAssertion( "protein sequestering") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "maintenance of protein localization") -AnnotationAssertion( "GO:0045185") -AnnotationAssertion(rdfs:label "maintenance of protein location") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (regulation of circadian sleep/wake cycle, sleep) AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0192800981") "Any process that modulates the frequency, rate or extent of sleep; a readily reversible state of reduced awareness and metabolic activity that occurs periodically in many animals.") @@ -84264,7 +25582,6 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0045187") AnnotationAssertion(rdfs:label "regulation of circadian sleep/wake cycle, sleep") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) # Class: (regulation of circadian sleep/wake cycle, non-REM sleep) @@ -84274,61 +25591,8 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0045188") AnnotationAssertion(rdfs:label "regulation of circadian sleep/wake cycle, non-REM sleep") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (isotype switching) - -AnnotationAssertion(Annotation( "ISBN:0781735149") "The switching of activated B cells from IgM biosynthesis to biosynthesis of other isotypes of immunoglobulin, accomplished through a recombination process involving an intrachromosomal deletion involving switch regions that reside 5' of each constant region gene segment in the immunoglobulin heavy chain locus.") -AnnotationAssertion( "Wikipedia:Immunoglobulin_class_switching") -AnnotationAssertion( "class switch recombination") -AnnotationAssertion( "class switching") -AnnotationAssertion( "isotype switch recombination") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045190") -AnnotationAssertion(rdfs:comment "Note that IgM and IgD can be coexpressed by B cells via an alternate splicing mechanism, but true recombinational isotype switching to IgD has been demonstrated as well. Note that this term is best used to annotate gene products which are involved in the mechanism of DNA recombination used in isotype switching, like the B cell specific Swap70 factor in the mouse, rather than gene products which promote isotype switching such as cytokines or co-stimulatory molecules, which should instead be annotated to 'regulation of isotype switching ; GO:0045191'.") -AnnotationAssertion(rdfs:label "isotype switching") -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of isotype switching) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of isotype switching.") -AnnotationAssertion( "regulation of class switch recombination") -AnnotationAssertion( "regulation of class switching") -AnnotationAssertion( "regulation of isotype switch recombination") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045191") -AnnotationAssertion(rdfs:label "regulation of isotype switching") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (establishment or maintenance of neuroblast polarity) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:mah") Annotation( "GOC:mtg_sensu") Annotation( "PMID:19375318") Annotation( "PMID:20066083") "Any cellular process that results in the specification, formation or maintenance of the apicobasal polarity of a neuroblast cell, a progenitor of the central nervous system.") -AnnotationAssertion( "GO:0043339") -AnnotationAssertion( "GO:0043342") -AnnotationAssertion( "establishment and/or maintenance of neuroblast cell polarity") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045196") -AnnotationAssertion(rdfs:label "establishment or maintenance of neuroblast polarity") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (establishment of neuroblast polarity) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:mtg_sensu") "The specification and formation of the apicobasal polarity of a neuroblast cell, a progenitor of the central nervous system.") -AnnotationAssertion( "GO:0043340") -AnnotationAssertion( "GO:0043343") -AnnotationAssertion( "establishment of neuroblast cell polarity") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045200") -AnnotationAssertion(rdfs:label "establishment of neuroblast polarity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - # Class: (synapse) AnnotationAssertion(Annotation( "GOC:aruk") Annotation( "ISBN:0198506732") Annotation( "PMID:24619342") Annotation( "PMID:29383328") Annotation( "PMID:31998110") "The junction between an axon of one neuron and a dendrite of another neuron, a muscle fiber or a glial cell. As the axon approaches the synapse it enlarges into a specialized structure, the presynaptic terminal bouton, which contains mitochondria and synaptic vesicles. At the tip of the terminal bouton is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic terminal bouton secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane.") @@ -84350,134 +25614,6 @@ SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectAllValuesFrom( )) -# Class: (postsynaptic membrane) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "A specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft). Neurotransmitters cross the synaptic cleft and transmit the signal to the postsynaptic membrane.") -AnnotationAssertion( "post-synaptic membrane") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0045211") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "postsynaptic membrane") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (sarcomere organization) - -AnnotationAssertion(Annotation( "GOC:bf") "The myofibril assembly process that results in the organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs.") -AnnotationAssertion( "GO:0006938") -AnnotationAssertion( "sarcomere alignment") -AnnotationAssertion( "sarcomere organisation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045214") -AnnotationAssertion(rdfs:label "sarcomere organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cell-cell junction organization) - -AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:dph") Annotation( "GOC:jl") Annotation( "GOC:mah") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cell-cell junction. A cell-cell junction is a specialized region of connection between two cells.") -AnnotationAssertion( "cell-cell junction assembly and maintenance") -AnnotationAssertion(Annotation( "GOC:mah") "cell-cell junction organisation") -AnnotationAssertion( "intercellular junction assembly and maintenance") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "cell-cell junction biogenesis") -AnnotationAssertion( "GO:0045216") -AnnotationAssertion(rdfs:label "cell-cell junction organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (CD4 biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of CD4, a CD marker that occurs on T-helper cells and is involved in MHC class II restricted interactions.") -AnnotationAssertion( "CD4 anabolism") -AnnotationAssertion( "CD4 biosynthesis") -AnnotationAssertion( "CD4 formation") -AnnotationAssertion( "CD4 synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045222") -AnnotationAssertion(rdfs:label "CD4 biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of CD4 production) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of CD4.") -AnnotationAssertion( "regulation of CD4 anabolism") -AnnotationAssertion( "regulation of CD4 biosynthesis") -AnnotationAssertion( "regulation of CD4 biosynthetic process") -AnnotationAssertion( "regulation of CD4 formation") -AnnotationAssertion( "regulation of CD4 synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045223") -AnnotationAssertion(rdfs:label "regulation of CD4 production") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of CD4 production) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of CD4.") -AnnotationAssertion( "positive regulation of CD4 anabolism") -AnnotationAssertion( "positive regulation of CD4 biosynthesis") -AnnotationAssertion( "positive regulation of CD4 biosynthetic process") -AnnotationAssertion( "positive regulation of CD4 formation") -AnnotationAssertion( "positive regulation of CD4 synthesis") -AnnotationAssertion( "up regulation of CD4 biosynthetic process") -AnnotationAssertion( "up-regulation of CD4 biosynthetic process") -AnnotationAssertion( "upregulation of CD4 biosynthetic process") -AnnotationAssertion( "activation of CD4 biosynthetic process") -AnnotationAssertion( "stimulation of CD4 biosynthetic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045224") -AnnotationAssertion(rdfs:label "positive regulation of CD4 production") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of CD4 production) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of CD4.") -AnnotationAssertion( "down regulation of CD4 biosynthetic process") -AnnotationAssertion( "down-regulation of CD4 biosynthetic process") -AnnotationAssertion( "downregulation of CD4 biosynthetic process") -AnnotationAssertion( "negative regulation of CD4 anabolism") -AnnotationAssertion( "negative regulation of CD4 biosynthesis") -AnnotationAssertion( "negative regulation of CD4 biosynthetic process") -AnnotationAssertion( "negative regulation of CD4 formation") -AnnotationAssertion( "negative regulation of CD4 synthesis") -AnnotationAssertion( "inhibition of CD4 biosynthetic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045225") -AnnotationAssertion(rdfs:label "negative regulation of CD4 production") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (external encapsulating structure organization) - -AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:dph") Annotation( "GOC:jl") Annotation( "GOC:mah") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of external structures that lie outside the plasma membrane and surround the entire cell.") -AnnotationAssertion( "external encapsulating structure organisation") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:jl") Annotation( "GOC:mah") "external encapsulating structure organization and biogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045229") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "external encapsulating structure organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (cadherin binding) - -AnnotationAssertion(Annotation( "GOC:bf") "Binding to cadherin, a type I membrane protein involved in cell adhesion.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0045296") -AnnotationAssertion(rdfs:label "cadherin binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (otolith mineralization) - -AnnotationAssertion(Annotation( "GOC:dsf") Annotation( "PMID:15581873") "The precipitation of specific crystal forms of calcium carbonate with extracellular matrix proteins in the otolith organs of the vertebrate inner ear.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045299") -AnnotationAssertion(rdfs:label "otolith mineralization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (leukocyte activation) AnnotationAssertion(Annotation( "GOC:add") "A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor.") @@ -84487,7 +25623,6 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0045321") AnnotationAssertion(rdfs:label "leukocyte activation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) @@ -84499,2849 +25634,8 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:0045443") AnnotationAssertion(rdfs:label "juvenile hormone secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (fat cell differentiation) - -AnnotationAssertion(Annotation( "CL:0000136") Annotation( "GOC:go_curators") "The process in which a relatively unspecialized cell acquires specialized features of an adipocyte, an animal connective tissue cell specialized for the synthesis and storage of fat.") -AnnotationAssertion( "adipocyte cell differentiation") -AnnotationAssertion( "adipocyte differentiation") -AnnotationAssertion( "adipose cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "adipogenesis") -AnnotationAssertion( "GO:0045444") -AnnotationAssertion(rdfs:label "fat cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (myoblast differentiation) - -AnnotationAssertion(Annotation( "CL:0000056") Annotation( "GOC:go_curators") Annotation( "GOC:mtg_muscle") "The process in which a relatively unspecialized cell acquires specialized features of a myoblast. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into striated muscle fibers.") -AnnotationAssertion( "myoblast cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045445") -AnnotationAssertion(rdfs:label "myoblast differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (endothelial cell differentiation) - -AnnotationAssertion(Annotation( "CL:0000115") Annotation( "GOC:go_curators") "The process in which a mesodermal, bone marrow or neural crest cell acquires specialized features of an endothelial cell, a thin flattened cell. A layer of such cells lines the inside surfaces of body cavities, blood vessels, and lymph vessels, making up the endothelium.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045446") -AnnotationAssertion(rdfs:label "endothelial cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (bone resorption) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "PMID:10968780") "The process in which specialized cells known as osteoclasts degrade the organic and inorganic portions of bone, and endocytose and transport the degradation products.") -AnnotationAssertion( "Wikipedia:Bone_resorption") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045453") -AnnotationAssertion(rdfs:label "bone resorption") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (regulation of imaginal disc growth) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of the growth of the imaginal disc.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045570") -AnnotationAssertion(rdfs:label "regulation of imaginal disc growth") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of imaginal disc growth) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of imaginal disc growth.") -AnnotationAssertion( "down regulation of imaginal disc growth") -AnnotationAssertion( "down-regulation of imaginal disc growth") -AnnotationAssertion( "downregulation of imaginal disc growth") -AnnotationAssertion( "inhibition of imaginal disc growth") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045571") -AnnotationAssertion(rdfs:label "negative regulation of imaginal disc growth") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of imaginal disc growth) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of imaginal disc growth.") -AnnotationAssertion( "up regulation of imaginal disc growth") -AnnotationAssertion( "up-regulation of imaginal disc growth") -AnnotationAssertion( "upregulation of imaginal disc growth") -AnnotationAssertion( "activation of imaginal disc growth") -AnnotationAssertion( "stimulation of imaginal disc growth") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045572") -AnnotationAssertion(rdfs:label "positive regulation of imaginal disc growth") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of B cell differentiation) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of B cell differentiation.") -AnnotationAssertion( "regulation of B lymphocyte differentiation") -AnnotationAssertion( "regulation of B-cell differentiation") -AnnotationAssertion( "regulation of B-lymphocyte differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:add") "regulation of B cell development") -AnnotationAssertion( "GO:0045577") -AnnotationAssertion(rdfs:comment "Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.") -AnnotationAssertion(rdfs:label "regulation of B cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of B cell differentiation) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of B cell differentiation.") -AnnotationAssertion( "down regulation of B cell differentiation") -AnnotationAssertion( "down-regulation of B cell differentiation") -AnnotationAssertion( "downregulation of B cell differentiation") -AnnotationAssertion( "negative regulation of B lymphocyte differentiation") -AnnotationAssertion( "negative regulation of B-cell differentiation") -AnnotationAssertion( "negative regulation of B-lymphocyte differentiation") -AnnotationAssertion( "inhibition of B cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:add") "negative regulation of B cell development") -AnnotationAssertion( "GO:0045578") -AnnotationAssertion(rdfs:comment "Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.") -AnnotationAssertion(rdfs:label "negative regulation of B cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of B cell differentiation) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of B cell differentiation.") -AnnotationAssertion( "positive regulation of B lymphocyte differentiation") -AnnotationAssertion( "positive regulation of B-cell differentiation") -AnnotationAssertion( "positive regulation of B-lymphocyte differentiation") -AnnotationAssertion( "up regulation of B cell differentiation") -AnnotationAssertion( "up-regulation of B cell differentiation") -AnnotationAssertion( "upregulation of B cell differentiation") -AnnotationAssertion( "activation of B cell differentiation") -AnnotationAssertion( "stimulation of B cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:add") "positive regulation of B cell development") -AnnotationAssertion( "GO:0045579") -AnnotationAssertion(rdfs:comment "Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.") -AnnotationAssertion(rdfs:label "positive regulation of B cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of T cell differentiation) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of T cell differentiation.") -AnnotationAssertion( "regulation of T lymphocyte differentiation") -AnnotationAssertion( "regulation of T-cell differentiation") -AnnotationAssertion( "regulation of T-lymphocyte differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:add") "regulation of T cell development") -AnnotationAssertion( "GO:0045580") -AnnotationAssertion(rdfs:comment "Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.") -AnnotationAssertion(rdfs:label "regulation of T cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of T cell differentiation) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of T cell differentiation.") -AnnotationAssertion( "down regulation of T cell differentiation") -AnnotationAssertion( "down-regulation of T cell differentiation") -AnnotationAssertion( "downregulation of T cell differentiation") -AnnotationAssertion( "negative regulation of T lymphocyte differentiation") -AnnotationAssertion( "negative regulation of T-cell differentiation") -AnnotationAssertion( "negative regulation of T-lymphocyte differentiation") -AnnotationAssertion( "inhibition of T cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:add") "negative regulation of T cell development") -AnnotationAssertion( "GO:0045581") -AnnotationAssertion(rdfs:comment "Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.") -AnnotationAssertion(rdfs:label "negative regulation of T cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of T cell differentiation) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of T cell differentiation.") -AnnotationAssertion( "positive regulation of T lymphocyte differentiation") -AnnotationAssertion( "positive regulation of T-cell differentiation") -AnnotationAssertion( "positive regulation of T-lymphocyte differentiation") -AnnotationAssertion( "up regulation of T cell differentiation") -AnnotationAssertion( "up-regulation of T cell differentiation") -AnnotationAssertion( "upregulation of T cell differentiation") -AnnotationAssertion( "activation of T cell differentiation") -AnnotationAssertion( "stimulation of T cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:add") "positive regulation of T cell development") -AnnotationAssertion( "GO:0045582") -AnnotationAssertion(rdfs:comment "Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.") -AnnotationAssertion(rdfs:label "positive regulation of T cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of cell differentiation) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of cell differentiation, the process in which relatively unspecialized cells acquire specialized structural and functional features.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045595") -AnnotationAssertion(rdfs:label "regulation of cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of cell differentiation) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of cell differentiation.") -AnnotationAssertion( "down regulation of cell differentiation") -AnnotationAssertion( "down-regulation of cell differentiation") -AnnotationAssertion( "downregulation of cell differentiation") -AnnotationAssertion( "inhibition of cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045596") -AnnotationAssertion(rdfs:label "negative regulation of cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of cell differentiation) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of cell differentiation.") -AnnotationAssertion( "up regulation of cell differentiation") -AnnotationAssertion( "up-regulation of cell differentiation") -AnnotationAssertion( "upregulation of cell differentiation") -AnnotationAssertion( "activation of cell differentiation") -AnnotationAssertion( "stimulation of cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045597") -AnnotationAssertion(rdfs:label "positive regulation of cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of fat cell differentiation) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of adipocyte differentiation.") -AnnotationAssertion( "regulation of adipocyte cell differentiation") -AnnotationAssertion( "regulation of adipocyte differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045598") -AnnotationAssertion(rdfs:label "regulation of fat cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of fat cell differentiation) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of adipocyte differentiation.") -AnnotationAssertion( "down regulation of fat cell differentiation") -AnnotationAssertion( "down-regulation of fat cell differentiation") -AnnotationAssertion( "downregulation of fat cell differentiation") -AnnotationAssertion( "negative regulation of adipocyte cell differentiation") -AnnotationAssertion( "negative regulation of adipocyte differentiation") -AnnotationAssertion( "inhibition of fat cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045599") -AnnotationAssertion(rdfs:label "negative regulation of fat cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of fat cell differentiation) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of adipocyte differentiation.") -AnnotationAssertion( "positive regulation of adipocyte cell differentiation") -AnnotationAssertion( "positive regulation of adipocyte differentiation") -AnnotationAssertion( "up regulation of fat cell differentiation") -AnnotationAssertion( "up-regulation of fat cell differentiation") -AnnotationAssertion( "upregulation of fat cell differentiation") -AnnotationAssertion( "activation of fat cell differentiation") -AnnotationAssertion( "stimulation of fat cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045600") -AnnotationAssertion(rdfs:label "positive regulation of fat cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of endothelial cell differentiation) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of endothelial cell differentiation.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045601") -AnnotationAssertion(rdfs:label "regulation of endothelial cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of endothelial cell differentiation) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of endothelial cell differentiation.") -AnnotationAssertion( "down regulation of endothelial cell differentiation") -AnnotationAssertion( "down-regulation of endothelial cell differentiation") -AnnotationAssertion( "downregulation of endothelial cell differentiation") -AnnotationAssertion( "inhibition of endothelial cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045602") -AnnotationAssertion(rdfs:label "negative regulation of endothelial cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of endothelial cell differentiation) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of endothelial cell differentiation.") -AnnotationAssertion( "up regulation of endothelial cell differentiation") -AnnotationAssertion( "up-regulation of endothelial cell differentiation") -AnnotationAssertion( "upregulation of endothelial cell differentiation") -AnnotationAssertion( "activation of endothelial cell differentiation") -AnnotationAssertion( "stimulation of endothelial cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045603") -AnnotationAssertion(rdfs:label "positive regulation of endothelial cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of epidermal cell differentiation) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of epidermal cell differentiation.") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:kmv") Annotation( "GOC:rk") "regulation of hypodermal cell differentiation") -AnnotationAssertion( "GO:0045604") -AnnotationAssertion(rdfs:label "regulation of epidermal cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of epidermal cell differentiation) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of epidermal cell differentiation.") -AnnotationAssertion( "down regulation of epidermal cell differentiation") -AnnotationAssertion( "down-regulation of epidermal cell differentiation") -AnnotationAssertion( "downregulation of epidermal cell differentiation") -AnnotationAssertion( "inhibition of epidermal cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:kmv") Annotation( "GOC:rk") "negative regulation of hypodermal cell differentiation") -AnnotationAssertion( "GO:0045605") -AnnotationAssertion(rdfs:label "negative regulation of epidermal cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of epidermal cell differentiation) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of epidermal cell differentiation.") -AnnotationAssertion( "up regulation of epidermal cell differentiation") -AnnotationAssertion( "up-regulation of epidermal cell differentiation") -AnnotationAssertion( "upregulation of epidermal cell differentiation") -AnnotationAssertion( "activation of epidermal cell differentiation") -AnnotationAssertion( "stimulation of epidermal cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:kmv") Annotation( "GOC:rk") "positive regulation of hypodermal cell differentiation") -AnnotationAssertion( "GO:0045606") -AnnotationAssertion(rdfs:label "positive regulation of epidermal cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of inner ear auditory receptor cell differentiation) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of auditory hair cell differentiation.") -AnnotationAssertion( "regulation of auditory hair cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "regulation of auditory receptor cell differentiation") -AnnotationAssertion( "GO:0045607") -AnnotationAssertion(rdfs:label "regulation of inner ear auditory receptor cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of inner ear auditory receptor cell differentiation) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of auditory hair cell differentiation.") -AnnotationAssertion( "down regulation of auditory receptor cell differentiation") -AnnotationAssertion( "down-regulation of auditory receptor cell differentiation") -AnnotationAssertion( "downregulation of auditory receptor cell differentiation") -AnnotationAssertion( "negative regulation of auditory hair cell differentiation") -AnnotationAssertion( "inhibition of auditory receptor cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "negative regulation of auditory receptor cell differentiation") -AnnotationAssertion( "GO:0045608") -AnnotationAssertion(rdfs:label "negative regulation of inner ear auditory receptor cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of inner ear auditory receptor cell differentiation) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of auditory hair cell differentiation.") -AnnotationAssertion( "positive regulation of auditory hair cell differentiation") -AnnotationAssertion( "up regulation of auditory receptor cell differentiation") -AnnotationAssertion( "up-regulation of auditory receptor cell differentiation") -AnnotationAssertion( "upregulation of auditory receptor cell differentiation") -AnnotationAssertion( "activation of auditory receptor cell differentiation") -AnnotationAssertion( "stimulation of auditory receptor cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "positive regulation of auditory receptor cell differentiation") -AnnotationAssertion( "GO:0045609") -AnnotationAssertion(rdfs:label "positive regulation of inner ear auditory receptor cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of hemocyte differentiation) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of hemocyte differentiation.") -AnnotationAssertion( "regulation of arthropod blood cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045610") -AnnotationAssertion(rdfs:label "regulation of hemocyte differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (negative regulation of hemocyte differentiation) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of hemocyte differentiation.") -AnnotationAssertion( "down regulation of hemocyte differentiation") -AnnotationAssertion( "down-regulation of hemocyte differentiation") -AnnotationAssertion( "downregulation of hemocyte differentiation") -AnnotationAssertion( "negative regulation of arthropod blood cell differentiation") -AnnotationAssertion( "inhibition of hemocyte differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045611") -AnnotationAssertion(rdfs:label "negative regulation of hemocyte differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of hemocyte differentiation) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of hemocyte differentiation.") -AnnotationAssertion( "positive regulation of arthropod blood cell differentiation") -AnnotationAssertion( "up regulation of hemocyte differentiation") -AnnotationAssertion( "up-regulation of hemocyte differentiation") -AnnotationAssertion( "upregulation of hemocyte differentiation") -AnnotationAssertion( "activation of hemocyte differentiation") -AnnotationAssertion( "stimulation of hemocyte differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045612") -AnnotationAssertion(rdfs:label "positive regulation of hemocyte differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of keratinocyte differentiation) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of keratinocyte differentiation.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045616") -AnnotationAssertion(rdfs:label "regulation of keratinocyte differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (negative regulation of keratinocyte differentiation) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of keratinocyte differentiation.") -AnnotationAssertion( "down regulation of keratinocyte differentiation") -AnnotationAssertion( "down-regulation of keratinocyte differentiation") -AnnotationAssertion( "downregulation of keratinocyte differentiation") -AnnotationAssertion( "inhibition of keratinocyte differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045617") -AnnotationAssertion(rdfs:label "negative regulation of keratinocyte differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of keratinocyte differentiation) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of keratinocyte differentiation.") -AnnotationAssertion( "up regulation of keratinocyte differentiation") -AnnotationAssertion( "up-regulation of keratinocyte differentiation") -AnnotationAssertion( "upregulation of keratinocyte differentiation") -AnnotationAssertion( "activation of keratinocyte differentiation") -AnnotationAssertion( "stimulation of keratinocyte differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045618") -AnnotationAssertion(rdfs:label "positive regulation of keratinocyte differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of lymphocyte differentiation) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of lymphocyte differentiation.") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:add") "regulation of lymphocyte development") -AnnotationAssertion( "GO:0045619") -AnnotationAssertion(rdfs:comment "Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.") -AnnotationAssertion(rdfs:label "regulation of lymphocyte differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of lymphocyte differentiation) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte differentiation.") -AnnotationAssertion( "down regulation of lymphocyte differentiation") -AnnotationAssertion( "down-regulation of lymphocyte differentiation") -AnnotationAssertion( "downregulation of lymphocyte differentiation") -AnnotationAssertion( "inhibition of lymphocyte differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:add") "negative regulation of lymphocyte development") -AnnotationAssertion( "GO:0045620") -AnnotationAssertion(rdfs:comment "Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.") -AnnotationAssertion(rdfs:label "negative regulation of lymphocyte differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of lymphocyte differentiation) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of lymphocyte differentiation.") -AnnotationAssertion( "up regulation of lymphocyte differentiation") -AnnotationAssertion( "up-regulation of lymphocyte differentiation") -AnnotationAssertion( "upregulation of lymphocyte differentiation") -AnnotationAssertion( "activation of lymphocyte differentiation") -AnnotationAssertion( "stimulation of lymphocyte differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:add") "positive regulation of lymphocyte development") -AnnotationAssertion( "GO:0045621") -AnnotationAssertion(rdfs:comment "Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.") -AnnotationAssertion(rdfs:label "positive regulation of lymphocyte differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of mechanoreceptor differentiation) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of mechanoreceptor differentiation.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045631") -AnnotationAssertion(rdfs:label "regulation of mechanoreceptor differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of mechanoreceptor differentiation) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of mechanoreceptor differentiation.") -AnnotationAssertion( "down regulation of mechanoreceptor differentiation") -AnnotationAssertion( "down-regulation of mechanoreceptor differentiation") -AnnotationAssertion( "downregulation of mechanoreceptor differentiation") -AnnotationAssertion( "inhibition of mechanoreceptor differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045632") -AnnotationAssertion(rdfs:label "negative regulation of mechanoreceptor differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of mechanoreceptor differentiation) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of mechanoreceptor differentiation.") -AnnotationAssertion( "up regulation of mechanoreceptor differentiation") -AnnotationAssertion( "up-regulation of mechanoreceptor differentiation") -AnnotationAssertion( "upregulation of mechanoreceptor differentiation") -AnnotationAssertion( "activation of mechanoreceptor differentiation") -AnnotationAssertion( "stimulation of mechanoreceptor differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045633") -AnnotationAssertion(rdfs:label "positive regulation of mechanoreceptor differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of melanocyte differentiation) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of melanocyte differentiation.") -AnnotationAssertion( "regulation of melanophore differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045634") -AnnotationAssertion(rdfs:label "regulation of melanocyte differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of melanocyte differentiation) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of melanocyte differentiation.") -AnnotationAssertion( "down regulation of melanocyte differentiation") -AnnotationAssertion( "down-regulation of melanocyte differentiation") -AnnotationAssertion( "downregulation of melanocyte differentiation") -AnnotationAssertion( "negative regulation of melanophore differentiation") -AnnotationAssertion( "inhibition of melanocyte differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045635") -AnnotationAssertion(rdfs:label "negative regulation of melanocyte differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of melanocyte differentiation) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of melanocyte differentiation.") -AnnotationAssertion( "positive regulation of melanophore differentiation") -AnnotationAssertion( "up regulation of melanocyte differentiation") -AnnotationAssertion( "up-regulation of melanocyte differentiation") -AnnotationAssertion( "upregulation of melanocyte differentiation") -AnnotationAssertion( "activation of melanocyte differentiation") -AnnotationAssertion( "stimulation of melanocyte differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045636") -AnnotationAssertion(rdfs:label "positive regulation of melanocyte differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of myeloid cell differentiation) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of myeloid cell differentiation.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045637") -AnnotationAssertion(rdfs:label "regulation of myeloid cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (negative regulation of myeloid cell differentiation) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of myeloid cell differentiation.") -AnnotationAssertion( "down regulation of myeloid cell differentiation") -AnnotationAssertion( "down-regulation of myeloid cell differentiation") -AnnotationAssertion( "downregulation of myeloid cell differentiation") -AnnotationAssertion( "inhibition of myeloid cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045638") -AnnotationAssertion(rdfs:label "negative regulation of myeloid cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of myeloid cell differentiation) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of myeloid cell differentiation.") -AnnotationAssertion( "up regulation of myeloid cell differentiation") -AnnotationAssertion( "up-regulation of myeloid cell differentiation") -AnnotationAssertion( "upregulation of myeloid cell differentiation") -AnnotationAssertion( "activation of myeloid cell differentiation") -AnnotationAssertion( "stimulation of myeloid cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045639") -AnnotationAssertion(rdfs:label "positive regulation of myeloid cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of erythrocyte differentiation) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of erythrocyte differentiation.") -AnnotationAssertion(Annotation( "CL:0000232") "regulation of RBC differentiation") -AnnotationAssertion(Annotation( "CL:0000232") "regulation of red blood cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045646") -AnnotationAssertion(rdfs:label "regulation of erythrocyte differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of erythrocyte differentiation) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of erythrocyte differentiation.") -AnnotationAssertion( "down regulation of erythrocyte differentiation") -AnnotationAssertion( "down-regulation of erythrocyte differentiation") -AnnotationAssertion( "downregulation of erythrocyte differentiation") -AnnotationAssertion(Annotation( "CL:0000232") "negative regulation of RBC differentiation") -AnnotationAssertion(Annotation( "CL:0000232") "negative regulation of red blood cell differentiation") -AnnotationAssertion( "inhibition of erythrocyte differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045647") -AnnotationAssertion(rdfs:label "negative regulation of erythrocyte differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of erythrocyte differentiation) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of erythrocyte differentiation.") -AnnotationAssertion(Annotation( "CL:0000232") "positive regulation of RBC differentiation") -AnnotationAssertion(Annotation( "CL:0000232") "positive regulation of red blood cell differentiation") -AnnotationAssertion( "up regulation of erythrocyte differentiation") -AnnotationAssertion( "up-regulation of erythrocyte differentiation") -AnnotationAssertion( "upregulation of erythrocyte differentiation") -AnnotationAssertion( "activation of erythrocyte differentiation") -AnnotationAssertion( "stimulation of erythrocyte differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045648") -AnnotationAssertion(rdfs:label "positive regulation of erythrocyte differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of macrophage differentiation) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of macrophage differentiation.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045649") -AnnotationAssertion(rdfs:label "regulation of macrophage differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of macrophage differentiation) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of macrophage differentiation.") -AnnotationAssertion( "down regulation of macrophage differentiation") -AnnotationAssertion( "down-regulation of macrophage differentiation") -AnnotationAssertion( "downregulation of macrophage differentiation") -AnnotationAssertion( "inhibition of macrophage differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045650") -AnnotationAssertion(rdfs:label "negative regulation of macrophage differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of macrophage differentiation) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of macrophage differentiation.") -AnnotationAssertion( "up regulation of macrophage differentiation") -AnnotationAssertion( "up-regulation of macrophage differentiation") -AnnotationAssertion( "upregulation of macrophage differentiation") -AnnotationAssertion( "activation of macrophage differentiation") -AnnotationAssertion( "stimulation of macrophage differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045651") -AnnotationAssertion(rdfs:label "positive regulation of macrophage differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of megakaryocyte differentiation) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of megakaryocyte differentiation.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045652") -AnnotationAssertion(rdfs:label "regulation of megakaryocyte differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of megakaryocyte differentiation) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of megakaryocyte differentiation.") -AnnotationAssertion( "down regulation of megakaryocyte differentiation") -AnnotationAssertion( "down-regulation of megakaryocyte differentiation") -AnnotationAssertion( "downregulation of megakaryocyte differentiation") -AnnotationAssertion( "inhibition of megakaryocyte differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045653") -AnnotationAssertion(rdfs:label "negative regulation of megakaryocyte differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of megakaryocyte differentiation) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of megakaryocyte differentiation.") -AnnotationAssertion( "up regulation of megakaryocyte differentiation") -AnnotationAssertion( "up-regulation of megakaryocyte differentiation") -AnnotationAssertion( "upregulation of megakaryocyte differentiation") -AnnotationAssertion( "activation of megakaryocyte differentiation") -AnnotationAssertion( "stimulation of megakaryocyte differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045654") -AnnotationAssertion(rdfs:label "positive regulation of megakaryocyte differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of monocyte differentiation) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of monocyte differentiation.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045655") -AnnotationAssertion(rdfs:label "regulation of monocyte differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of monocyte differentiation) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of monocyte differentiation.") -AnnotationAssertion( "down regulation of monocyte differentiation") -AnnotationAssertion( "down-regulation of monocyte differentiation") -AnnotationAssertion( "downregulation of monocyte differentiation") -AnnotationAssertion( "inhibition of monocyte differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045656") -AnnotationAssertion(rdfs:label "negative regulation of monocyte differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of monocyte differentiation) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of monocyte differentiation.") -AnnotationAssertion( "up regulation of monocyte differentiation") -AnnotationAssertion( "up-regulation of monocyte differentiation") -AnnotationAssertion( "upregulation of monocyte differentiation") -AnnotationAssertion( "activation of monocyte differentiation") -AnnotationAssertion( "stimulation of monocyte differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045657") -AnnotationAssertion(rdfs:label "positive regulation of monocyte differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of neutrophil differentiation) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of neutrophil differentiation.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045658") -AnnotationAssertion(rdfs:label "regulation of neutrophil differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of neutrophil differentiation) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of neutrophil differentiation.") -AnnotationAssertion( "down regulation of neutrophil differentiation") -AnnotationAssertion( "down-regulation of neutrophil differentiation") -AnnotationAssertion( "downregulation of neutrophil differentiation") -AnnotationAssertion( "inhibition of neutrophil differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045659") -AnnotationAssertion(rdfs:label "negative regulation of neutrophil differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of neutrophil differentiation) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of neutrophil differentiation.") -AnnotationAssertion( "up regulation of neutrophil differentiation") -AnnotationAssertion( "up-regulation of neutrophil differentiation") -AnnotationAssertion( "upregulation of neutrophil differentiation") -AnnotationAssertion( "activation of neutrophil differentiation") -AnnotationAssertion( "stimulation of neutrophil differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045660") -AnnotationAssertion(rdfs:label "positive regulation of neutrophil differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of myoblast differentiation) - -AnnotationAssertion(Annotation( "CL:0000056") Annotation( "GOC:go_curators") Annotation( "GOC:mtg_muscle") "Any process that modulates the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045661") -AnnotationAssertion(rdfs:label "regulation of myoblast differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of myoblast differentiation) - -AnnotationAssertion(Annotation( "CL:0000056") Annotation( "GOC:go_curators") Annotation( "GOC:mtg_muscle") "Any process that stops, prevents, or reduces the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.") -AnnotationAssertion( "down regulation of myoblast differentiation") -AnnotationAssertion( "down-regulation of myoblast differentiation") -AnnotationAssertion( "downregulation of myoblast differentiation") -AnnotationAssertion( "inhibition of myoblast differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045662") -AnnotationAssertion(rdfs:label "negative regulation of myoblast differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of myoblast differentiation) - -AnnotationAssertion(Annotation( "CL:0000056") Annotation( "GOC:go_curators") Annotation( "GOC:mtg_muscle") "Any process that activates or increases the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.") -AnnotationAssertion( "up regulation of myoblast differentiation") -AnnotationAssertion( "up-regulation of myoblast differentiation") -AnnotationAssertion( "upregulation of myoblast differentiation") -AnnotationAssertion( "activation of myoblast differentiation") -AnnotationAssertion( "stimulation of myoblast differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045663") -AnnotationAssertion(rdfs:label "positive regulation of myoblast differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of neuron differentiation) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of neuron differentiation.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045664") -AnnotationAssertion(rdfs:label "regulation of neuron differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - -# Class: (negative regulation of neuron differentiation) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of neuron differentiation.") -AnnotationAssertion( "down regulation of neuron differentiation") -AnnotationAssertion( "down-regulation of neuron differentiation") -AnnotationAssertion( "downregulation of neuron differentiation") -AnnotationAssertion( "inhibition of neuron differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045665") -AnnotationAssertion(rdfs:label "negative regulation of neuron differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of neuron differentiation) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of neuron differentiation.") -AnnotationAssertion( "up regulation of neuron differentiation") -AnnotationAssertion( "up-regulation of neuron differentiation") -AnnotationAssertion( "upregulation of neuron differentiation") -AnnotationAssertion( "activation of neuron differentiation") -AnnotationAssertion( "stimulation of neuron differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045666") -AnnotationAssertion(rdfs:label "positive regulation of neuron differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of osteoblast differentiation) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of osteoblast differentiation.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045667") -AnnotationAssertion(rdfs:label "regulation of osteoblast differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of osteoblast differentiation) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of osteoblast differentiation.") -AnnotationAssertion( "down regulation of osteoblast differentiation") -AnnotationAssertion( "down-regulation of osteoblast differentiation") -AnnotationAssertion( "downregulation of osteoblast differentiation") -AnnotationAssertion( "inhibition of osteoblast differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045668") -AnnotationAssertion(rdfs:label "negative regulation of osteoblast differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of osteoblast differentiation) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of osteoblast differentiation.") -AnnotationAssertion( "up regulation of osteoblast differentiation") -AnnotationAssertion( "up-regulation of osteoblast differentiation") -AnnotationAssertion( "upregulation of osteoblast differentiation") -AnnotationAssertion( "activation of osteoblast differentiation") -AnnotationAssertion( "stimulation of osteoblast differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045669") -AnnotationAssertion(rdfs:label "positive regulation of osteoblast differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of osteoclast differentiation) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of osteoclast differentiation.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045670") -AnnotationAssertion(rdfs:label "regulation of osteoclast differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of osteoclast differentiation) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of osteoclast differentiation.") -AnnotationAssertion( "down regulation of osteoclast differentiation") -AnnotationAssertion( "down-regulation of osteoclast differentiation") -AnnotationAssertion( "downregulation of osteoclast differentiation") -AnnotationAssertion( "inhibition of osteoclast differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045671") -AnnotationAssertion(rdfs:label "negative regulation of osteoclast differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of osteoclast differentiation) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of osteoclast differentiation.") -AnnotationAssertion( "up regulation of osteoclast differentiation") -AnnotationAssertion( "up-regulation of osteoclast differentiation") -AnnotationAssertion( "upregulation of osteoclast differentiation") -AnnotationAssertion( "activation of osteoclast differentiation") -AnnotationAssertion( "stimulation of osteoclast differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045672") -AnnotationAssertion(rdfs:label "positive regulation of osteoclast differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of epidermis development) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of epidermis development.") -AnnotationAssertion( "regulation of epidermal development") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:kmv") Annotation( "GOC:rk") "regulation of hypodermis development") -AnnotationAssertion( "GO:0045682") -AnnotationAssertion(rdfs:label "regulation of epidermis development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (negative regulation of epidermis development) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of epidermis development.") -AnnotationAssertion( "down regulation of epidermis development") -AnnotationAssertion( "down-regulation of epidermis development") -AnnotationAssertion( "downregulation of epidermis development") -AnnotationAssertion( "negative regulation of epidermal development") -AnnotationAssertion( "inhibition of epidermis development") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:kmv") Annotation( "GOC:rk") "negative regulation of hypodermis development") -AnnotationAssertion( "GO:0045683") -AnnotationAssertion(rdfs:label "negative regulation of epidermis development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of epidermis development) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of epidermis development.") -AnnotationAssertion( "positive regulation of epidermal development") -AnnotationAssertion( "up regulation of epidermis development") -AnnotationAssertion( "up-regulation of epidermis development") -AnnotationAssertion( "upregulation of epidermis development") -AnnotationAssertion( "activation of epidermis development") -AnnotationAssertion( "stimulation of epidermis development") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:kmv") Annotation( "GOC:rk") "positive regulation of hypodermis development") -AnnotationAssertion( "GO:0045684") -AnnotationAssertion(rdfs:label "positive regulation of epidermis development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of glial cell differentiation) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of glia cell differentiation.") -AnnotationAssertion( "regulation of glia cell differentiation") -AnnotationAssertion( "regulation of neuroglia differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045685") -AnnotationAssertion(rdfs:label "regulation of glial cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of glial cell differentiation) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of glia cell differentiation.") -AnnotationAssertion( "down regulation of glial cell differentiation") -AnnotationAssertion( "down-regulation of glial cell differentiation") -AnnotationAssertion( "downregulation of glial cell differentiation") -AnnotationAssertion( "negative regulation of glia cell differentiation") -AnnotationAssertion( "negative regulation of neuroglia differentiation") -AnnotationAssertion( "inhibition of glial cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045686") -AnnotationAssertion(rdfs:label "negative regulation of glial cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (positive regulation of glial cell differentiation) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of glia cell differentiation.") -AnnotationAssertion( "positive regulation of glia cell differentiation") -AnnotationAssertion( "positive regulation of neuroglia differentiation") -AnnotationAssertion( "up regulation of glial cell differentiation") -AnnotationAssertion( "up-regulation of glial cell differentiation") -AnnotationAssertion( "upregulation of glial cell differentiation") -AnnotationAssertion( "activation of glial cell differentiation") -AnnotationAssertion( "stimulation of glial cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045687") -AnnotationAssertion(rdfs:label "positive regulation of glial cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of spermatid nuclear differentiation) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of spermatid nuclear differentiation.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045700") -AnnotationAssertion(rdfs:label "regulation of spermatid nuclear differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (negative regulation of spermatid nuclear differentiation) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of spermatid nuclear differentiation.") -AnnotationAssertion( "down regulation of spermatid nuclear differentiation") -AnnotationAssertion( "down-regulation of spermatid nuclear differentiation") -AnnotationAssertion( "downregulation of spermatid nuclear differentiation") -AnnotationAssertion( "inhibition of spermatid nuclear differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045701") -AnnotationAssertion(rdfs:label "negative regulation of spermatid nuclear differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of spermatid nuclear differentiation) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of spermatid nuclear differentiation.") -AnnotationAssertion( "up regulation of spermatid nuclear differentiation") -AnnotationAssertion( "up-regulation of spermatid nuclear differentiation") -AnnotationAssertion( "upregulation of spermatid nuclear differentiation") -AnnotationAssertion( "activation of spermatid nuclear differentiation") -AnnotationAssertion( "stimulation of spermatid nuclear differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045702") -AnnotationAssertion(rdfs:label "positive regulation of spermatid nuclear differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of fatty acid biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fatty acids.") -AnnotationAssertion( "down regulation of fatty acid biosynthetic process") -AnnotationAssertion( "down-regulation of fatty acid biosynthetic process") -AnnotationAssertion( "downregulation of fatty acid biosynthetic process") -AnnotationAssertion( "negative regulation of fatty acid anabolism") -AnnotationAssertion( "negative regulation of fatty acid biosynthesis") -AnnotationAssertion( "negative regulation of fatty acid formation") -AnnotationAssertion( "negative regulation of fatty acid synthesis") -AnnotationAssertion( "inhibition of fatty acid biosynthetic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045717") -AnnotationAssertion(rdfs:label "negative regulation of fatty acid biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of glycogen biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen.") -AnnotationAssertion( "down regulation of glycogen biosynthetic process") -AnnotationAssertion( "down-regulation of glycogen biosynthetic process") -AnnotationAssertion( "downregulation of glycogen biosynthetic process") -AnnotationAssertion( "negative regulation of glycogen anabolism") -AnnotationAssertion( "negative regulation of glycogen biosynthesis") -AnnotationAssertion( "negative regulation of glycogen formation") -AnnotationAssertion( "negative regulation of glycogen synthesis") -AnnotationAssertion( "inhibition of glycogen biosynthetic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045719") -AnnotationAssertion(rdfs:label "negative regulation of glycogen biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of gluconeogenesis) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of gluconeogenesis.") -AnnotationAssertion( "down regulation of gluconeogenesis") -AnnotationAssertion( "down-regulation of gluconeogenesis") -AnnotationAssertion( "downregulation of gluconeogenesis") -AnnotationAssertion( "inhibition of gluconeogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045721") -AnnotationAssertion(rdfs:label "negative regulation of gluconeogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of gluconeogenesis) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of gluconeogenesis.") -AnnotationAssertion( "up regulation of gluconeogenesis") -AnnotationAssertion( "up-regulation of gluconeogenesis") -AnnotationAssertion( "upregulation of gluconeogenesis") -AnnotationAssertion( "activation of gluconeogenesis") -AnnotationAssertion( "stimulation of gluconeogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045722") -AnnotationAssertion(rdfs:label "positive regulation of gluconeogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (positive regulation of fatty acid biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fatty acids.") -AnnotationAssertion( "positive regulation of fatty acid anabolism") -AnnotationAssertion( "positive regulation of fatty acid biosynthesis") -AnnotationAssertion( "positive regulation of fatty acid formation") -AnnotationAssertion( "positive regulation of fatty acid synthesis") -AnnotationAssertion( "up regulation of fatty acid biosynthetic process") -AnnotationAssertion( "up-regulation of fatty acid biosynthetic process") -AnnotationAssertion( "upregulation of fatty acid biosynthetic process") -AnnotationAssertion( "activation of fatty acid biosynthetic process") -AnnotationAssertion( "stimulation of fatty acid biosynthetic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045723") -AnnotationAssertion(rdfs:label "positive regulation of fatty acid biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of cilium assembly) - -AnnotationAssertion(Annotation( "GOC:cilia") Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of the formation of a cilium.") -AnnotationAssertion( "positive regulation of flagellum assembly") -AnnotationAssertion( "up regulation of cilium assembly") -AnnotationAssertion( "up-regulation of cilium assembly") -AnnotationAssertion( "upregulation of cilium assembly") -AnnotationAssertion( "activation of cilium assembly") -AnnotationAssertion( "stimulation of cilium assembly") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:mah") "positive regulation of flagellum biogenesis") -AnnotationAssertion( "GO:0045724") -AnnotationAssertion(rdfs:label "positive regulation of cilium assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of glycogen biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen.") -AnnotationAssertion( "positive regulation of glycogen anabolism") -AnnotationAssertion( "positive regulation of glycogen biosynthesis") -AnnotationAssertion( "positive regulation of glycogen formation") -AnnotationAssertion( "positive regulation of glycogen synthesis") -AnnotationAssertion( "up regulation of glycogen biosynthetic process") -AnnotationAssertion( "up-regulation of glycogen biosynthetic process") -AnnotationAssertion( "upregulation of glycogen biosynthetic process") -AnnotationAssertion( "activation of glycogen biosynthetic process") -AnnotationAssertion( "stimulation of glycogen biosynthetic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045725") -AnnotationAssertion(rdfs:label "positive regulation of glycogen biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of translation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:go_curators") Annotation( "GOC:tb") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA.") -AnnotationAssertion( "GO:0045946") -AnnotationAssertion( "positive regulation of protein anabolism") -AnnotationAssertion( "positive regulation of protein biosynthesis") -AnnotationAssertion(Annotation( "GOC:tb") "positive regulation of protein biosynthetic process") -AnnotationAssertion( "positive regulation of protein formation") -AnnotationAssertion( "positive regulation of protein synthesis") -AnnotationAssertion( "up regulation of protein biosynthetic process") -AnnotationAssertion( "up-regulation of protein biosynthetic process") -AnnotationAssertion( "upregulation of protein biosynthetic process") -AnnotationAssertion( "activation of protein biosynthetic process") -AnnotationAssertion( "stimulation of protein biosynthetic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045727") -AnnotationAssertion(rdfs:label "positive regulation of translation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of protein catabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/23112"^^xsd:anyURI) -AnnotationAssertion( "GO:1903364") -AnnotationAssertion( "GO:2000600") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of cellular protein breakdown") -AnnotationAssertion( "positive regulation of cellular protein catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of cellular protein catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of cellular protein degradation") -AnnotationAssertion( "positive regulation of protein breakdown") -AnnotationAssertion( "positive regulation of protein catabolism") -AnnotationAssertion( "positive regulation of protein degradation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of cellular protein breakdown") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of cellular protein catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of cellular protein catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of cellular protein degradation") -AnnotationAssertion( "up regulation of protein catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of cellular protein breakdown") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of cellular protein catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of cellular protein catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of cellular protein degradation") -AnnotationAssertion( "up-regulation of protein catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of cellular protein breakdown") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of cellular protein catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of cellular protein catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of cellular protein degradation") -AnnotationAssertion( "upregulation of protein catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of cellular protein breakdown") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of cellular protein catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of cellular protein catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of cellular protein degradation") -AnnotationAssertion( "activation of protein catabolic process") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of cyclin breakdown") -AnnotationAssertion( "positive regulation of cyclin catabolic process") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of cyclin catabolism") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of cyclin degradation") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of degradation of cyclin") -AnnotationAssertion( "stimulation of protein catabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045732") -AnnotationAssertion(rdfs:label "positive regulation of protein catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (acetate catabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways resulting in the breakdown of acetate, the anion of acetic acid.") -AnnotationAssertion( "GO:0019663") -AnnotationAssertion( "acetate breakdown") -AnnotationAssertion( "acetate catabolism") -AnnotationAssertion( "acetate degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "homoacetate catabolic process") -AnnotationAssertion( "GO:0045733") -AnnotationAssertion(rdfs:label "acetate catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of acetate catabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of acetate, the anion of acetic acid.") -AnnotationAssertion( "regulation of acetate breakdown") -AnnotationAssertion( "regulation of acetate catabolism") -AnnotationAssertion( "regulation of acetate degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045734") -AnnotationAssertion(rdfs:label "regulation of acetate catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (negative regulation of G protein-coupled receptor signaling pathway) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of G protein-coupled receptor signaling pathway.") -AnnotationAssertion( "down regulation of G-protein coupled receptor protein signaling pathway") -AnnotationAssertion( "down-regulation of G-protein coupled receptor protein signaling pathway") -AnnotationAssertion( "downregulation of G-protein coupled receptor protein signaling pathway") -AnnotationAssertion( "negative regulation of G protein coupled receptor protein signaling pathway") -AnnotationAssertion( "negative regulation of G protein coupled receptor protein signalling pathway") -AnnotationAssertion( "negative regulation of G-protein coupled receptor protein signaling pathway") -AnnotationAssertion( "negative regulation of G-protein coupled receptor protein signalling pathway") -AnnotationAssertion( "negative regulation of G-protein-coupled receptor protein signalling pathway") -AnnotationAssertion( "negative regulation of GPCR protein signaling pathway") -AnnotationAssertion( "negative regulation of GPCR protein signalling pathway") -AnnotationAssertion( "inhibition of G-protein coupled receptor protein signaling pathway") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045744") -AnnotationAssertion(rdfs:label "negative regulation of G protein-coupled receptor signaling pathway") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of G protein-coupled receptor signaling pathway) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of G protein-coupled receptor signaling pathway activity.") -AnnotationAssertion( "positive regulation of G protein coupled receptor protein signaling pathway") -AnnotationAssertion( "positive regulation of G protein coupled receptor protein signalling pathway") -AnnotationAssertion( "positive regulation of G-protein coupled receptor protein signaling pathway") -AnnotationAssertion( "positive regulation of G-protein coupled receptor protein signalling pathway") -AnnotationAssertion( "positive regulation of G-protein-coupled receptor protein signaling pathway") -AnnotationAssertion( "positive regulation of G-protein-coupled receptor protein signalling pathway") -AnnotationAssertion( "positive regulation of GPCR protein signaling pathway") -AnnotationAssertion( "positive regulation of GPCR protein signalling pathway") -AnnotationAssertion( "up regulation of G-protein coupled receptor protein signaling pathway") -AnnotationAssertion( "up-regulation of G-protein coupled receptor protein signaling pathway") -AnnotationAssertion( "upregulation of G-protein coupled receptor protein signaling pathway") -AnnotationAssertion( "activation of G-protein coupled receptor protein signaling pathway") -AnnotationAssertion( "stimulation of G-protein coupled receptor protein signaling pathway") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045745") -AnnotationAssertion(rdfs:label "positive regulation of G protein-coupled receptor signaling pathway") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of acetate catabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of acetate.") -AnnotationAssertion( "down regulation of acetate catabolic process") -AnnotationAssertion( "down-regulation of acetate catabolic process") -AnnotationAssertion( "downregulation of acetate catabolic process") -AnnotationAssertion( "negative regulation of acetate breakdown") -AnnotationAssertion( "negative regulation of acetate catabolism") -AnnotationAssertion( "negative regulation of acetate degradation") -AnnotationAssertion( "inhibition of acetate catabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045753") -AnnotationAssertion(rdfs:label "negative regulation of acetate catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of acetate catabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of acetate.") -AnnotationAssertion( "positive regulation of acetate breakdown") -AnnotationAssertion( "positive regulation of acetate catabolism") -AnnotationAssertion( "positive regulation of acetate degradation") -AnnotationAssertion( "up regulation of acetate catabolic process") -AnnotationAssertion( "up-regulation of acetate catabolic process") -AnnotationAssertion( "upregulation of acetate catabolic process") -AnnotationAssertion( "activation of acetate catabolic process") -AnnotationAssertion( "stimulation of acetate catabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045754") -AnnotationAssertion(rdfs:label "positive regulation of acetate catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of action potential) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of action potential creation, propagation or termination. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.") -AnnotationAssertion( "down regulation of action potential") -AnnotationAssertion( "down-regulation of action potential") -AnnotationAssertion( "downregulation of action potential") -AnnotationAssertion( "inhibition of action potential") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045759") -AnnotationAssertion(rdfs:label "negative regulation of action potential") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (positive regulation of action potential) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of action potential creation, propagation or termination. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.") -AnnotationAssertion( "up regulation of action potential") -AnnotationAssertion( "up-regulation of action potential") -AnnotationAssertion( "upregulation of action potential") -AnnotationAssertion( "activation of action potential") -AnnotationAssertion( "stimulation of action potential") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045760") -AnnotationAssertion(rdfs:label "positive regulation of action potential") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (negative regulation of cellular amino acid metabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amino acid.") -AnnotationAssertion( "down regulation of amino acid metabolic process") -AnnotationAssertion( "down-regulation of amino acid metabolic process") -AnnotationAssertion( "downregulation of amino acid metabolic process") -AnnotationAssertion( "negative regulation of amino acid metabolism") -AnnotationAssertion( "inhibition of amino acid metabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045763") -AnnotationAssertion(rdfs:label "negative regulation of cellular amino acid metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of amino acid metabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amino acid.") -AnnotationAssertion( "positive regulation of amino acid metabolism") -AnnotationAssertion( "positive regulation of cellular amino acid metabolic process") -AnnotationAssertion( "up regulation of amino acid metabolic process") -AnnotationAssertion( "up-regulation of amino acid metabolic process") -AnnotationAssertion( "upregulation of amino acid metabolic process") -AnnotationAssertion( "activation of amino acid metabolic process") -AnnotationAssertion( "stimulation of amino acid metabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045764") -AnnotationAssertion(rdfs:label "positive regulation of amino acid metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of angiogenesis) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of angiogenesis.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045765") -AnnotationAssertion(rdfs:label "regulation of angiogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of angiogenesis) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases angiogenesis.") -AnnotationAssertion( "up regulation of angiogenesis") -AnnotationAssertion( "up-regulation of angiogenesis") -AnnotationAssertion( "upregulation of angiogenesis") -AnnotationAssertion( "activation of angiogenesis") -AnnotationAssertion( "stimulation of angiogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045766") -AnnotationAssertion(rdfs:label "positive regulation of angiogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of asymmetric cell division) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of asymmetric cell division.") -AnnotationAssertion( "down regulation of asymmetric cell division") -AnnotationAssertion( "down-regulation of asymmetric cell division") -AnnotationAssertion( "downregulation of asymmetric cell division") -AnnotationAssertion( "inhibition of asymmetric cell division") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045769") -AnnotationAssertion(rdfs:label "negative regulation of asymmetric cell division") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of asymmetric cell division) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of asymmetric cell division.") -AnnotationAssertion( "up regulation of asymmetric cell division") -AnnotationAssertion( "up-regulation of asymmetric cell division") -AnnotationAssertion( "upregulation of asymmetric cell division") -AnnotationAssertion( "activation of asymmetric cell division") -AnnotationAssertion( "stimulation of asymmetric cell division") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045770") -AnnotationAssertion(rdfs:label "positive regulation of asymmetric cell division") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of ossification) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance.") -AnnotationAssertion( "positive regulation of bone biosynthesis") -AnnotationAssertion( "positive regulation of bone formation") -AnnotationAssertion( "up regulation of ossification") -AnnotationAssertion( "up-regulation of ossification") -AnnotationAssertion( "upregulation of ossification") -AnnotationAssertion( "activation of ossification") -AnnotationAssertion( "stimulation of ossification") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045778") -AnnotationAssertion(rdfs:label "positive regulation of ossification") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of bone resorption) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of bone resorption.") -AnnotationAssertion( "down regulation of bone resorption") -AnnotationAssertion( "down-regulation of bone resorption") -AnnotationAssertion( "downregulation of bone resorption") -AnnotationAssertion( "inhibition of bone resorption") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045779") -AnnotationAssertion(rdfs:label "negative regulation of bone resorption") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of bone resorption) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of bone resorption.") -AnnotationAssertion( "up regulation of bone resorption") -AnnotationAssertion( "up-regulation of bone resorption") -AnnotationAssertion( "upregulation of bone resorption") -AnnotationAssertion( "activation of bone resorption") -AnnotationAssertion( "stimulation of bone resorption") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045780") -AnnotationAssertion(rdfs:label "positive regulation of bone resorption") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of cell adhesion) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of cell adhesion.") -AnnotationAssertion( "up regulation of cell adhesion") -AnnotationAssertion( "up-regulation of cell adhesion") -AnnotationAssertion( "upregulation of cell adhesion") -AnnotationAssertion( "activation of cell adhesion") -AnnotationAssertion( "stimulation of cell adhesion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045785") -AnnotationAssertion(rdfs:label "positive regulation of cell adhesion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of cell cycle) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:go_curators") Annotation( "GOC:tb") "Any process that stops, prevents or reduces the rate or extent of progression through the cell cycle.") -AnnotationAssertion( "down regulation of progression through cell cycle") -AnnotationAssertion( "down-regulation of progression through cell cycle") -AnnotationAssertion( "downregulation of progression through cell cycle") -AnnotationAssertion( "negative regulation of cell cycle progression") -AnnotationAssertion( "negative regulation of progression through cell cycle") -AnnotationAssertion( "inhibition of progression through cell cycle") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045786") -AnnotationAssertion(rdfs:label "negative regulation of cell cycle") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of cell cycle) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the rate or extent of progression through the cell cycle.") -AnnotationAssertion( "positive regulation of cell cycle progression") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "positive regulation of progression through cell cycle") -AnnotationAssertion( "up regulation of progression through cell cycle") -AnnotationAssertion( "up-regulation of progression through cell cycle") -AnnotationAssertion( "upregulation of progression through cell cycle") -AnnotationAssertion( "activation of progression through cell cycle") -AnnotationAssertion( "stimulation of progression through cell cycle") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045787") -AnnotationAssertion(rdfs:label "positive regulation of cell cycle") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of eclosion) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of eclosion.") -AnnotationAssertion( "down regulation of eclosion") -AnnotationAssertion( "down-regulation of eclosion") -AnnotationAssertion( "downregulation of eclosion") -AnnotationAssertion( "inhibition of eclosion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045804") -AnnotationAssertion(rdfs:label "negative regulation of eclosion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of eclosion) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of eclosion.") -AnnotationAssertion( "up regulation of eclosion") -AnnotationAssertion( "up-regulation of eclosion") -AnnotationAssertion( "upregulation of eclosion") -AnnotationAssertion( "activation of eclosion") -AnnotationAssertion( "stimulation of eclosion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045805") -AnnotationAssertion(rdfs:label "positive regulation of eclosion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of endocytosis) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of endocytosis.") -AnnotationAssertion( "down regulation of endocytosis") -AnnotationAssertion( "down-regulation of endocytosis") -AnnotationAssertion( "downregulation of endocytosis") -AnnotationAssertion( "inhibition of endocytosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045806") -AnnotationAssertion(rdfs:label "negative regulation of endocytosis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (positive regulation of endocytosis) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of endocytosis.") -AnnotationAssertion( "up regulation of endocytosis") -AnnotationAssertion( "up-regulation of endocytosis") -AnnotationAssertion( "upregulation of endocytosis") -AnnotationAssertion( "activation of endocytosis") -AnnotationAssertion( "stimulation of endocytosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045807") -AnnotationAssertion(rdfs:label "positive regulation of endocytosis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (negative regulation of glycogen catabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glycogen.") -AnnotationAssertion( "down regulation of glycogen catabolic process") -AnnotationAssertion( "down-regulation of glycogen catabolic process") -AnnotationAssertion( "downregulation of glycogen catabolic process") -AnnotationAssertion( "negative regulation of glycogen breakdown") -AnnotationAssertion( "negative regulation of glycogen catabolism") -AnnotationAssertion( "negative regulation of glycogen degradation") -AnnotationAssertion(Annotation( "GOC:sl") "negative regulation of glycogenolysis") -AnnotationAssertion( "inhibition of glycogen catabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045818") -AnnotationAssertion(rdfs:label "negative regulation of glycogen catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of glycogen catabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glycogen.") -AnnotationAssertion( "positive regulation of glycogen breakdown") -AnnotationAssertion( "positive regulation of glycogen catabolism") -AnnotationAssertion( "positive regulation of glycogen degradation") -AnnotationAssertion(Annotation( "GOC:sl") "positive regulation of glycogenolysis") -AnnotationAssertion( "up regulation of glycogen catabolic process") -AnnotationAssertion( "up-regulation of glycogen catabolic process") -AnnotationAssertion( "upregulation of glycogen catabolic process") -AnnotationAssertion( "activation of glycogen catabolic process") -AnnotationAssertion( "stimulation of glycogen catabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045819") -AnnotationAssertion(rdfs:label "positive regulation of glycogen catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of heart contraction) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of heart contraction.") -AnnotationAssertion( "down regulation of heart contraction") -AnnotationAssertion( "down-regulation of heart contraction") -AnnotationAssertion( "downregulation of heart contraction") -AnnotationAssertion( "inhibition of heart contraction") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "negative regulation of cardiac contraction") -AnnotationAssertion( "GO:0045822") -AnnotationAssertion(rdfs:label "negative regulation of heart contraction") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of heart contraction) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of heart contraction.") -AnnotationAssertion( "positive regulation of cardiac contraction") -AnnotationAssertion( "up regulation of heart contraction") -AnnotationAssertion( "up-regulation of heart contraction") -AnnotationAssertion( "upregulation of heart contraction") -AnnotationAssertion( "activation of heart contraction") -AnnotationAssertion( "stimulation of heart contraction") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045823") -AnnotationAssertion(rdfs:label "positive regulation of heart contraction") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of isoprenoid metabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving isoprenoid.") -AnnotationAssertion( "down regulation of isoprenoid metabolic process") -AnnotationAssertion( "down-regulation of isoprenoid metabolic process") -AnnotationAssertion( "downregulation of isoprenoid metabolic process") -AnnotationAssertion( "negative regulation of isoprenoid metabolism") -AnnotationAssertion( "inhibition of isoprenoid metabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045827") -AnnotationAssertion(rdfs:label "negative regulation of isoprenoid metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of isoprenoid metabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving isoprenoid.") -AnnotationAssertion( "positive regulation of isoprenoid metabolism") -AnnotationAssertion( "up regulation of isoprenoid metabolic process") -AnnotationAssertion( "up-regulation of isoprenoid metabolic process") -AnnotationAssertion( "upregulation of isoprenoid metabolic process") -AnnotationAssertion( "activation of isoprenoid metabolic process") -AnnotationAssertion( "stimulation of isoprenoid metabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045828") -AnnotationAssertion(rdfs:label "positive regulation of isoprenoid metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of isotype switching) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of isotype switching.") -AnnotationAssertion( "down regulation of isotype switching") -AnnotationAssertion( "down-regulation of isotype switching") -AnnotationAssertion( "downregulation of isotype switching") -AnnotationAssertion( "negative regulation of class switch recombination") -AnnotationAssertion( "negative regulation of class switching") -AnnotationAssertion( "negative regulation of isotype switch recombination") -AnnotationAssertion( "inhibition of isotype switching") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045829") -AnnotationAssertion(rdfs:label "negative regulation of isotype switching") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of isotype switching) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of isotype switching.") -AnnotationAssertion( "positive regulation of class switch recombination") -AnnotationAssertion( "positive regulation of class switching") -AnnotationAssertion( "positive regulation of isotype switch recombination") -AnnotationAssertion( "up regulation of isotype switching") -AnnotationAssertion( "up-regulation of isotype switching") -AnnotationAssertion( "upregulation of isotype switching") -AnnotationAssertion( "activation of isotype switching") -AnnotationAssertion( "stimulation of isotype switching") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045830") -AnnotationAssertion(rdfs:label "positive regulation of isotype switching") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (negative regulation of lipid metabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving lipids.") -AnnotationAssertion( "down regulation of lipid metabolic process") -AnnotationAssertion( "down-regulation of lipid metabolic process") -AnnotationAssertion( "downregulation of lipid metabolic process") -AnnotationAssertion( "negative regulation of lipid metabolism") -AnnotationAssertion( "inhibition of lipid metabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045833") -AnnotationAssertion(rdfs:label "negative regulation of lipid metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of lipid metabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving lipids.") -AnnotationAssertion( "positive regulation of lipid metabolism") -AnnotationAssertion( "up regulation of lipid metabolic process") -AnnotationAssertion( "up-regulation of lipid metabolic process") -AnnotationAssertion( "upregulation of lipid metabolic process") -AnnotationAssertion( "activation of lipid metabolic process") -AnnotationAssertion( "stimulation of lipid metabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045834") -AnnotationAssertion(rdfs:label "positive regulation of lipid metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of meiotic nuclear division) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of meiosis.") -AnnotationAssertion( "down regulation of meiosis") -AnnotationAssertion( "down-regulation of meiosis") -AnnotationAssertion( "downregulation of meiosis") -AnnotationAssertion( "negative regulation of meiosis") -AnnotationAssertion( "inhibition of meiosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045835") -AnnotationAssertion(rdfs:label "negative regulation of meiotic nuclear division") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (positive regulation of meiotic nuclear division) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of meiosis.") -AnnotationAssertion( "positive regulation of meiosis") -AnnotationAssertion( "up regulation of meiosis") -AnnotationAssertion( "up-regulation of meiosis") -AnnotationAssertion( "upregulation of meiosis") -AnnotationAssertion( "activation of meiosis") -AnnotationAssertion( "stimulation of meiosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045836") -AnnotationAssertion(rdfs:label "positive regulation of meiotic nuclear division") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (negative regulation of mitotic nuclear division) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:go_curators") Annotation( "GOC:tb") "Any process that stops, prevents or reduces the rate or extent of mitosis. Mitosis is the division of the eukaryotic cell nucleus to produce two daughter nuclei that, usually, contain the identical chromosome complement to their mother.") -AnnotationAssertion( "down regulation of mitosis") -AnnotationAssertion( "down-regulation of mitosis") -AnnotationAssertion( "downregulation of mitosis") -AnnotationAssertion( "negative regulation of mitosis") -AnnotationAssertion( "inhibition of mitosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045839") -AnnotationAssertion(rdfs:label "negative regulation of mitotic nuclear division") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of mitotic nuclear division) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of mitosis.") -AnnotationAssertion( "positive regulation of mitosis") -AnnotationAssertion( "up regulation of mitosis") -AnnotationAssertion( "up-regulation of mitosis") -AnnotationAssertion( "upregulation of mitosis") -AnnotationAssertion( "activation of mitosis") -AnnotationAssertion( "mitogenic activity") -AnnotationAssertion( "stimulation of mitosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045840") -AnnotationAssertion(rdfs:label "positive regulation of mitotic nuclear division") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (negative regulation of striated muscle tissue development) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle development.") -AnnotationAssertion( "down regulation of striated muscle development") -AnnotationAssertion( "down-regulation of striated muscle development") -AnnotationAssertion( "downregulation of striated muscle development") -AnnotationAssertion( "inhibition of striated muscle development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045843") -AnnotationAssertion(rdfs:label "negative regulation of striated muscle tissue development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (positive regulation of striated muscle tissue development) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of striated muscle development.") -AnnotationAssertion( "up regulation of striated muscle development") -AnnotationAssertion( "up-regulation of striated muscle development") -AnnotationAssertion( "upregulation of striated muscle development") -AnnotationAssertion( "activation of striated muscle development") -AnnotationAssertion( "stimulation of striated muscle development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045844") -AnnotationAssertion(rdfs:label "positive regulation of striated muscle tissue development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (pH reduction) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that reduces the internal pH of an organism, part of an organism or a cell, measured by the concentration of the hydrogen ion.") -AnnotationAssertion( "acidification") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045851") -AnnotationAssertion(rdfs:label "pH reduction") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (pH elevation) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that increases the internal pH of an organism, part of an organism or a cell, measured by the concentration of the hydrogen ion.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045852") -AnnotationAssertion(rdfs:label "pH elevation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of protein kinase activity) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of protein kinase activity.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045859") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "regulation of protein kinase activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of protein kinase activity) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of protein kinase activity.") -AnnotationAssertion( "up regulation of protein kinase activity") -AnnotationAssertion( "up-regulation of protein kinase activity") -AnnotationAssertion( "upregulation of protein kinase activity") -AnnotationAssertion( "stimulation of protein kinase activity") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045860") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "positive regulation of protein kinase activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (negative regulation of proteolysis) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein.") -AnnotationAssertion( "down regulation of proteolysis") -AnnotationAssertion( "down-regulation of proteolysis") -AnnotationAssertion( "downregulation of proteolysis") -AnnotationAssertion( "negative regulation of peptidolysis") -AnnotationAssertion( "inhibition of proteolysis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045861") -AnnotationAssertion(rdfs:label "negative regulation of proteolysis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (positive regulation of proteolysis) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein.") -AnnotationAssertion( "positive regulation of peptidolysis") -AnnotationAssertion( "up regulation of proteolysis") -AnnotationAssertion( "up-regulation of proteolysis") -AnnotationAssertion( "upregulation of proteolysis") -AnnotationAssertion( "activation of proteolysis") -AnnotationAssertion( "stimulation of proteolysis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045862") -AnnotationAssertion(rdfs:label "positive regulation of proteolysis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (negative regulation of translational elongation) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of translational elongation.") -AnnotationAssertion( "down regulation of translational elongation") -AnnotationAssertion( "down-regulation of translational elongation") -AnnotationAssertion( "downregulation of translational elongation") -AnnotationAssertion( "inhibition of translational elongation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045900") -AnnotationAssertion(rdfs:label "negative regulation of translational elongation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (positive regulation of translational elongation) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of translational elongation.") -AnnotationAssertion( "up regulation of translational elongation") -AnnotationAssertion( "up-regulation of translational elongation") -AnnotationAssertion( "upregulation of translational elongation") -AnnotationAssertion( "activation of translational elongation") -AnnotationAssertion( "stimulation of translational elongation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045901") -AnnotationAssertion(rdfs:label "positive regulation of translational elongation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (negative regulation of translational termination) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of translational termination.") -AnnotationAssertion( "down regulation of translational termination") -AnnotationAssertion( "down-regulation of translational termination") -AnnotationAssertion( "downregulation of translational termination") -AnnotationAssertion( "inhibition of translational termination") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045904") -AnnotationAssertion(rdfs:label "negative regulation of translational termination") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (positive regulation of translational termination) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of translational termination.") -AnnotationAssertion( "up regulation of translational termination") -AnnotationAssertion( "up-regulation of translational termination") -AnnotationAssertion( "upregulation of translational termination") -AnnotationAssertion( "activation of translational termination") -AnnotationAssertion( "stimulation of translational termination") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045905") -AnnotationAssertion(rdfs:label "positive regulation of translational termination") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (negative regulation of DNA recombination) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of DNA recombination.") -AnnotationAssertion( "down regulation of DNA recombination") -AnnotationAssertion( "down-regulation of DNA recombination") -AnnotationAssertion( "downregulation of DNA recombination") -AnnotationAssertion( "inhibition of DNA recombination") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045910") -AnnotationAssertion(rdfs:label "negative regulation of DNA recombination") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of DNA recombination) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of DNA recombination.") -AnnotationAssertion( "up regulation of DNA recombination") -AnnotationAssertion( "up-regulation of DNA recombination") -AnnotationAssertion( "upregulation of DNA recombination") -AnnotationAssertion( "activation of DNA recombination") -AnnotationAssertion( "stimulation of DNA recombination") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045911") -AnnotationAssertion(rdfs:label "positive regulation of DNA recombination") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of carbohydrate metabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving carbohydrate.") -AnnotationAssertion( "down regulation of carbohydrate metabolic process") -AnnotationAssertion( "down-regulation of carbohydrate metabolic process") -AnnotationAssertion( "downregulation of carbohydrate metabolic process") -AnnotationAssertion( "negative regulation of carbohydrate metabolism") -AnnotationAssertion( "inhibition of carbohydrate metabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045912") -AnnotationAssertion(rdfs:label "negative regulation of carbohydrate metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of carbohydrate metabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving carbohydrate.") -AnnotationAssertion( "positive regulation of carbohydrate metabolism") -AnnotationAssertion( "up regulation of carbohydrate metabolic process") -AnnotationAssertion( "up-regulation of carbohydrate metabolic process") -AnnotationAssertion( "upregulation of carbohydrate metabolic process") -AnnotationAssertion( "activation of carbohydrate metabolic process") -AnnotationAssertion( "stimulation of carbohydrate metabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045913") -AnnotationAssertion(rdfs:label "positive regulation of carbohydrate metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of catecholamine metabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving catecholamine.") -AnnotationAssertion( "down regulation of catecholamine metabolic process") -AnnotationAssertion( "down-regulation of catecholamine metabolic process") -AnnotationAssertion( "downregulation of catecholamine metabolic process") -AnnotationAssertion( "negative regulation of catecholamine metabolism") -AnnotationAssertion( "inhibition of catecholamine metabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045914") -AnnotationAssertion(rdfs:label "negative regulation of catecholamine metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of catecholamine metabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving catecholamine.") -AnnotationAssertion( "positive regulation of catecholamine metabolism") -AnnotationAssertion( "up regulation of catecholamine metabolic process") -AnnotationAssertion( "up-regulation of catecholamine metabolic process") -AnnotationAssertion( "upregulation of catecholamine metabolic process") -AnnotationAssertion( "activation of catecholamine metabolic process") -AnnotationAssertion( "stimulation of catecholamine metabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045915") -AnnotationAssertion(rdfs:label "positive regulation of catecholamine metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of exocytosis) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of exocytosis.") -AnnotationAssertion( "down regulation of exocytosis") -AnnotationAssertion( "down-regulation of exocytosis") -AnnotationAssertion( "downregulation of exocytosis") -AnnotationAssertion( "inhibition of exocytosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045920") -AnnotationAssertion(rdfs:label "negative regulation of exocytosis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of exocytosis) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of exocytosis.") -AnnotationAssertion( "up regulation of exocytosis") -AnnotationAssertion( "up-regulation of exocytosis") -AnnotationAssertion( "upregulation of exocytosis") -AnnotationAssertion( "activation of exocytosis") -AnnotationAssertion( "stimulation of exocytosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045921") -AnnotationAssertion(rdfs:label "positive regulation of exocytosis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of fatty acid metabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving fatty acids.") -AnnotationAssertion( "down regulation of fatty acid metabolic process") -AnnotationAssertion( "down-regulation of fatty acid metabolic process") -AnnotationAssertion( "downregulation of fatty acid metabolic process") -AnnotationAssertion( "negative regulation of fatty acid metabolism") -AnnotationAssertion( "inhibition of fatty acid metabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045922") -AnnotationAssertion(rdfs:label "negative regulation of fatty acid metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of fatty acid metabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving fatty acids.") -AnnotationAssertion( "positive regulation of fatty acid metabolism") -AnnotationAssertion( "up regulation of fatty acid metabolic process") -AnnotationAssertion( "up-regulation of fatty acid metabolic process") -AnnotationAssertion( "upregulation of fatty acid metabolic process") -AnnotationAssertion( "activation of fatty acid metabolic process") -AnnotationAssertion( "stimulation of fatty acid metabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045923") -AnnotationAssertion(rdfs:label "positive regulation of fatty acid metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of growth) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents or reduces the rate or extent of growth, the increase in size or mass of all or part of an organism.") -AnnotationAssertion( "down regulation of growth") -AnnotationAssertion( "down-regulation of growth") -AnnotationAssertion( "downregulation of growth") -AnnotationAssertion( "inhibition of growth") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045926") -AnnotationAssertion(rdfs:label "negative regulation of growth") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of growth) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the rate or extent of growth, the increase in size or mass of all or part of an organism.") -AnnotationAssertion( "up regulation of growth") -AnnotationAssertion( "up-regulation of growth") -AnnotationAssertion( "upregulation of growth") -AnnotationAssertion( "activation of growth") -AnnotationAssertion( "stimulation of growth") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045927") -AnnotationAssertion(rdfs:label "positive regulation of growth") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of juvenile hormone metabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving juvenile hormone.") -AnnotationAssertion( "down regulation of juvenile hormone metabolic process") -AnnotationAssertion( "down-regulation of juvenile hormone metabolic process") -AnnotationAssertion( "downregulation of juvenile hormone metabolic process") -AnnotationAssertion( "negative regulation of juvenile hormone metabolism") -AnnotationAssertion( "inhibition of juvenile hormone metabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045928") -AnnotationAssertion(rdfs:label "negative regulation of juvenile hormone metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of juvenile hormone metabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving juvenile hormone.") -AnnotationAssertion( "positive regulation of juvenile hormone metabolism") -AnnotationAssertion( "up regulation of juvenile hormone metabolic process") -AnnotationAssertion( "up-regulation of juvenile hormone metabolic process") -AnnotationAssertion( "upregulation of juvenile hormone metabolic process") -AnnotationAssertion( "activation of juvenile hormone metabolic process") -AnnotationAssertion( "stimulation of juvenile hormone metabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045929") -AnnotationAssertion(rdfs:label "positive regulation of juvenile hormone metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of mitotic cell cycle) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:go_curators") Annotation( "GOC:tb") "Any process that stops, prevents or reduces the rate or extent of progression through the mitotic cell cycle.") -AnnotationAssertion( "down regulation of progression through mitotic cell cycle") -AnnotationAssertion( "down-regulation of progression through mitotic cell cycle") -AnnotationAssertion( "downregulation of progression through mitotic cell cycle") -AnnotationAssertion( "negative regulation of mitotic cell cycle progression") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "negative regulation of progression through mitotic cell cycle") -AnnotationAssertion( "inhibition of progression through mitotic cell cycle") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045930") -AnnotationAssertion(rdfs:label "negative regulation of mitotic cell cycle") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of mitotic cell cycle) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:go_curators") Annotation( "GOC:tb") "Any process that activates or increases the rate or extent of progression through the mitotic cell cycle.") -AnnotationAssertion( "positive regulation of mitotic cell cycle progression") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "positive regulation of progression through mitotic cell cycle") -AnnotationAssertion( "up regulation of progression through mitotic cell cycle") -AnnotationAssertion( "up-regulation of progression through mitotic cell cycle") -AnnotationAssertion( "upregulation of progression through mitotic cell cycle") -AnnotationAssertion( "activation of progression through mitotic cell cycle") -AnnotationAssertion( "stimulation of progression through mitotic cell cycle") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045931") -AnnotationAssertion(rdfs:label "positive regulation of mitotic cell cycle") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of muscle contraction) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of muscle contraction.") -AnnotationAssertion( "down regulation of muscle contraction") -AnnotationAssertion( "down-regulation of muscle contraction") -AnnotationAssertion( "downregulation of muscle contraction") -AnnotationAssertion( "inhibition of muscle contraction") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045932") -AnnotationAssertion(rdfs:label "negative regulation of muscle contraction") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of muscle contraction) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of muscle contraction.") -AnnotationAssertion( "up regulation of muscle contraction") -AnnotationAssertion( "up-regulation of muscle contraction") -AnnotationAssertion( "upregulation of muscle contraction") -AnnotationAssertion( "activation of muscle contraction") -AnnotationAssertion( "stimulation of muscle contraction") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045933") -AnnotationAssertion(rdfs:label "positive regulation of muscle contraction") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of nucleobase-containing compound metabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any cellular process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids.") -AnnotationAssertion( "down regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process") -AnnotationAssertion( "down-regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process") -AnnotationAssertion( "downregulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process") -AnnotationAssertion( "negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism") -AnnotationAssertion( "inhibition of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process") -AnnotationAssertion( "GO:0045934") -AnnotationAssertion(rdfs:label "negative regulation of nucleobase-containing compound metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of nucleobase-containing compound metabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any cellular process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids.") -AnnotationAssertion( "positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism") -AnnotationAssertion( "up regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process") -AnnotationAssertion( "up-regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process") -AnnotationAssertion( "upregulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process") -AnnotationAssertion( "activation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process") -AnnotationAssertion( "stimulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process") -AnnotationAssertion( "GO:0045935") -AnnotationAssertion(rdfs:label "positive regulation of nucleobase-containing compound metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of phosphate metabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving phosphates.") -AnnotationAssertion( "down regulation of phosphate metabolic process") -AnnotationAssertion( "down-regulation of phosphate metabolic process") -AnnotationAssertion( "downregulation of phosphate metabolic process") -AnnotationAssertion( "negative regulation of phosphate metabolism") -AnnotationAssertion( "inhibition of phosphate metabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045936") -AnnotationAssertion(rdfs:label "negative regulation of phosphate metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of phosphate metabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving phosphates.") -AnnotationAssertion( "positive regulation of phosphate metabolism") -AnnotationAssertion( "up regulation of phosphate metabolic process") -AnnotationAssertion( "up-regulation of phosphate metabolic process") -AnnotationAssertion( "upregulation of phosphate metabolic process") -AnnotationAssertion( "activation of phosphate metabolic process") -AnnotationAssertion( "stimulation of phosphate metabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045937") -AnnotationAssertion(rdfs:label "positive regulation of phosphate metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of circadian sleep/wake cycle, sleep) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the duration or quality of sleep, a readily reversible state of reduced awareness and metabolic activity that occurs periodically in many animals.") -AnnotationAssertion( "positive regulation of sleep") -AnnotationAssertion( "up regulation of circadian sleep/wake cycle, sleep") -AnnotationAssertion( "up-regulation of circadian sleep/wake cycle, sleep") -AnnotationAssertion( "upregulation of circadian sleep/wake cycle, sleep") -AnnotationAssertion( "activation of circadian sleep/wake cycle, sleep") -AnnotationAssertion( "stimulation of circadian sleep/wake cycle, sleep") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045938") -AnnotationAssertion(rdfs:label "positive regulation of circadian sleep/wake cycle, sleep") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of steroid metabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving steroids.") -AnnotationAssertion( "down regulation of steroid metabolic process") -AnnotationAssertion( "down-regulation of steroid metabolic process") -AnnotationAssertion( "downregulation of steroid metabolic process") -AnnotationAssertion( "negative regulation of steroid metabolism") -AnnotationAssertion( "inhibition of steroid metabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045939") -AnnotationAssertion(rdfs:label "negative regulation of steroid metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of steroid metabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving steroids.") -AnnotationAssertion( "positive regulation of steroid metabolism") -AnnotationAssertion( "up regulation of steroid metabolic process") -AnnotationAssertion( "up-regulation of steroid metabolic process") -AnnotationAssertion( "upregulation of steroid metabolic process") -AnnotationAssertion( "activation of steroid metabolic process") -AnnotationAssertion( "stimulation of steroid metabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045940") -AnnotationAssertion(rdfs:label "positive regulation of steroid metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of translational initiation) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of translational initiation.") -AnnotationAssertion( "down regulation of translational initiation") -AnnotationAssertion( "down-regulation of translational initiation") -AnnotationAssertion( "downregulation of translational initiation") -AnnotationAssertion( "inhibition of translational initiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045947") -AnnotationAssertion(rdfs:label "negative regulation of translational initiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (positive regulation of translational initiation) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of translational initiation.") -AnnotationAssertion( "up regulation of translational initiation") -AnnotationAssertion( "up-regulation of translational initiation") -AnnotationAssertion( "upregulation of translational initiation") -AnnotationAssertion( "activation of translational initiation") -AnnotationAssertion( "stimulation of translational initiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045948") -AnnotationAssertion(rdfs:label "positive regulation of translational initiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of juvenile hormone catabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of juvenile hormone.") -AnnotationAssertion( "regulation of juvenile hormone breakdown") -AnnotationAssertion( "regulation of juvenile hormone catabolism") -AnnotationAssertion( "regulation of juvenile hormone degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045952") -AnnotationAssertion(rdfs:label "regulation of juvenile hormone catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of dopamine metabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving dopamine.") -AnnotationAssertion( "down regulation of dopamine metabolic process") -AnnotationAssertion( "down-regulation of dopamine metabolic process") -AnnotationAssertion( "downregulation of dopamine metabolic process") -AnnotationAssertion( "negative regulation of dopamine metabolism") -AnnotationAssertion( "inhibition of dopamine metabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045963") -AnnotationAssertion(rdfs:label "negative regulation of dopamine metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of dopamine metabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving dopamine.") -AnnotationAssertion( "positive regulation of dopamine metabolism") -AnnotationAssertion( "up regulation of dopamine metabolic process") -AnnotationAssertion( "up-regulation of dopamine metabolic process") -AnnotationAssertion( "upregulation of dopamine metabolic process") -AnnotationAssertion( "activation of dopamine metabolic process") -AnnotationAssertion( "stimulation of dopamine metabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045964") -AnnotationAssertion(rdfs:label "positive regulation of dopamine metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of juvenile hormone biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of juvenile hormone.") -AnnotationAssertion( "down regulation of juvenile hormone biosynthetic process") -AnnotationAssertion( "down-regulation of juvenile hormone biosynthetic process") -AnnotationAssertion( "downregulation of juvenile hormone biosynthetic process") -AnnotationAssertion( "negative regulation of juvenile hormone anabolism") -AnnotationAssertion( "negative regulation of juvenile hormone biosynthesis") -AnnotationAssertion( "negative regulation of juvenile hormone formation") -AnnotationAssertion( "negative regulation of juvenile hormone synthesis") -AnnotationAssertion( "inhibition of juvenile hormone biosynthetic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045968") -AnnotationAssertion(rdfs:label "negative regulation of juvenile hormone biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of juvenile hormone biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of juvenile hormone.") -AnnotationAssertion( "positive regulation of juvenile hormone anabolism") -AnnotationAssertion( "positive regulation of juvenile hormone biosynthesis") -AnnotationAssertion( "positive regulation of juvenile hormone formation") -AnnotationAssertion( "positive regulation of juvenile hormone synthesis") -AnnotationAssertion( "up regulation of juvenile hormone biosynthetic process") -AnnotationAssertion( "up-regulation of juvenile hormone biosynthetic process") -AnnotationAssertion( "upregulation of juvenile hormone biosynthetic process") -AnnotationAssertion( "activation of juvenile hormone biosynthetic process") -AnnotationAssertion( "stimulation of juvenile hormone biosynthetic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045969") -AnnotationAssertion(rdfs:label "positive regulation of juvenile hormone biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of juvenile hormone catabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of juvenile hormone.") -AnnotationAssertion( "down regulation of juvenile hormone catabolic process") -AnnotationAssertion( "down-regulation of juvenile hormone catabolic process") -AnnotationAssertion( "downregulation of juvenile hormone catabolic process") -AnnotationAssertion( "negative regulation of juvenile hormone breakdown") -AnnotationAssertion( "negative regulation of juvenile hormone catabolism") -AnnotationAssertion( "negative regulation of juvenile hormone degradation") -AnnotationAssertion( "inhibition of juvenile hormone catabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045970") -AnnotationAssertion(rdfs:label "negative regulation of juvenile hormone catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of juvenile hormone catabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of juvenile hormone.") -AnnotationAssertion( "positive regulation of juvenile hormone breakdown") -AnnotationAssertion( "positive regulation of juvenile hormone catabolism") -AnnotationAssertion( "positive regulation of juvenile hormone degradation") -AnnotationAssertion( "up regulation of juvenile hormone catabolic process") -AnnotationAssertion( "up-regulation of juvenile hormone catabolic process") -AnnotationAssertion( "upregulation of juvenile hormone catabolic process") -AnnotationAssertion( "activation of juvenile hormone catabolic process") -AnnotationAssertion( "stimulation of juvenile hormone catabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045971") -AnnotationAssertion(rdfs:label "positive regulation of juvenile hormone catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of juvenile hormone secretion) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of juvenile hormone.") -AnnotationAssertion( "down regulation of juvenile hormone secretion") -AnnotationAssertion( "down-regulation of juvenile hormone secretion") -AnnotationAssertion( "downregulation of juvenile hormone secretion") -AnnotationAssertion( "inhibition of juvenile hormone secretion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045972") -AnnotationAssertion(rdfs:label "negative regulation of juvenile hormone secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of juvenile hormone secretion) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of the regulated release of juvenile hormone.") -AnnotationAssertion( "up regulation of juvenile hormone secretion") -AnnotationAssertion( "up-regulation of juvenile hormone secretion") -AnnotationAssertion( "upregulation of juvenile hormone secretion") -AnnotationAssertion( "activation of juvenile hormone secretion") -AnnotationAssertion( "stimulation of juvenile hormone secretion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045973") -AnnotationAssertion(rdfs:label "positive regulation of juvenile hormone secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of nucleoside metabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleosides.") -AnnotationAssertion( "down regulation of nucleoside metabolic process") -AnnotationAssertion( "down-regulation of nucleoside metabolic process") -AnnotationAssertion( "downregulation of nucleoside metabolic process") -AnnotationAssertion( "negative regulation of nucleoside metabolism") -AnnotationAssertion( "inhibition of nucleoside metabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045978") -AnnotationAssertion(rdfs:label "negative regulation of nucleoside metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of nucleoside metabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nucleosides.") -AnnotationAssertion( "positive regulation of nucleoside metabolism") -AnnotationAssertion( "up regulation of nucleoside metabolic process") -AnnotationAssertion( "up-regulation of nucleoside metabolic process") -AnnotationAssertion( "upregulation of nucleoside metabolic process") -AnnotationAssertion( "activation of nucleoside metabolic process") -AnnotationAssertion( "stimulation of nucleoside metabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045979") -AnnotationAssertion(rdfs:label "positive regulation of nucleoside metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of nucleotide metabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleotides.") -AnnotationAssertion( "down regulation of nucleotide metabolic process") -AnnotationAssertion( "down-regulation of nucleotide metabolic process") -AnnotationAssertion( "downregulation of nucleotide metabolic process") -AnnotationAssertion( "negative regulation of nucleotide metabolism") -AnnotationAssertion( "inhibition of nucleotide metabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045980") -AnnotationAssertion(rdfs:label "negative regulation of nucleotide metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of nucleotide metabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nucleotides.") -AnnotationAssertion( "positive regulation of nucleotide metabolism") -AnnotationAssertion( "up regulation of nucleotide metabolic process") -AnnotationAssertion( "up-regulation of nucleotide metabolic process") -AnnotationAssertion( "upregulation of nucleotide metabolic process") -AnnotationAssertion( "activation of nucleotide metabolic process") -AnnotationAssertion( "stimulation of nucleotide metabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045981") -AnnotationAssertion(rdfs:label "positive regulation of nucleotide metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of purine nucleobase metabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving purine nucleobases.") -AnnotationAssertion( "down regulation of purine base metabolic process") -AnnotationAssertion( "down-regulation of purine base metabolic process") -AnnotationAssertion( "downregulation of purine base metabolic process") -AnnotationAssertion(Annotation( "GOC:go_curators") "negative regulation of purine base metabolic process") -AnnotationAssertion( "negative regulation of purine base metabolism") -AnnotationAssertion( "inhibition of purine base metabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045982") -AnnotationAssertion(rdfs:label "negative regulation of purine nucleobase metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of purine nucleobase metabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving purine bases.") -AnnotationAssertion( "positive regulation of purine base metabolic process") -AnnotationAssertion( "positive regulation of purine base metabolism") -AnnotationAssertion( "up regulation of purine base metabolic process") -AnnotationAssertion( "up-regulation of purine base metabolic process") -AnnotationAssertion( "upregulation of purine base metabolic process") -AnnotationAssertion( "activation of purine base metabolic process") -AnnotationAssertion( "stimulation of purine base metabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045983") -AnnotationAssertion(rdfs:label "positive regulation of purine nucleobase metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of smooth muscle contraction) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle contraction.") -AnnotationAssertion( "down regulation of smooth muscle contraction") -AnnotationAssertion( "down-regulation of smooth muscle contraction") -AnnotationAssertion( "downregulation of smooth muscle contraction") -AnnotationAssertion( "inhibition of smooth muscle contraction") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "smooth muscle relaxation") -AnnotationAssertion( "GO:0045986") -AnnotationAssertion(rdfs:label "negative regulation of smooth muscle contraction") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of smooth muscle contraction) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of smooth muscle contraction.") -AnnotationAssertion( "up regulation of smooth muscle contraction") -AnnotationAssertion( "up-regulation of smooth muscle contraction") -AnnotationAssertion( "upregulation of smooth muscle contraction") -AnnotationAssertion( "activation of smooth muscle contraction") -AnnotationAssertion( "stimulation of smooth muscle contraction") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045987") -AnnotationAssertion(rdfs:label "positive regulation of smooth muscle contraction") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of striated muscle contraction) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle contraction.") -AnnotationAssertion( "down regulation of striated muscle contraction") -AnnotationAssertion( "down-regulation of striated muscle contraction") -AnnotationAssertion( "downregulation of striated muscle contraction") -AnnotationAssertion( "inhibition of striated muscle contraction") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045988") -AnnotationAssertion(rdfs:label "negative regulation of striated muscle contraction") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of striated muscle contraction) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of striated muscle contraction.") -AnnotationAssertion( "up regulation of striated muscle contraction") -AnnotationAssertion( "up-regulation of striated muscle contraction") -AnnotationAssertion( "upregulation of striated muscle contraction") -AnnotationAssertion( "activation of striated muscle contraction") -AnnotationAssertion( "stimulation of striated muscle contraction") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045989") -AnnotationAssertion(rdfs:label "positive regulation of striated muscle contraction") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of embryonic development) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of embryonic development.") -AnnotationAssertion( "down regulation of embryonic development") -AnnotationAssertion( "down-regulation of embryonic development") -AnnotationAssertion( "downregulation of embryonic development") -AnnotationAssertion( "inhibition of embryonic development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045992") -AnnotationAssertion(rdfs:label "negative regulation of embryonic development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of embryonic development) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of embryonic development.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0045995") -AnnotationAssertion(rdfs:label "regulation of embryonic development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (positive regulation of circadian sleep/wake cycle, non-REM sleep) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the duration or quality of non-rapid eye movement (NREM) sleep.") -AnnotationAssertion( "positive regulation of non-REM sleep") -AnnotationAssertion( "up regulation of circadian sleep/wake cycle, non-REM sleep") -AnnotationAssertion( "up-regulation of circadian sleep/wake cycle, non-REM sleep") -AnnotationAssertion( "upregulation of circadian sleep/wake cycle, non-REM sleep") -AnnotationAssertion( "activation of circadian sleep/wake cycle, non-REM sleep") -AnnotationAssertion( "stimulation of circadian sleep/wake cycle, non-REM sleep") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046010") -AnnotationAssertion(rdfs:label "positive regulation of circadian sleep/wake cycle, non-REM sleep") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of T cell homeostatic proliferation) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of resting T cell proliferation.") -AnnotationAssertion( "regulation of T lymphocyte homeostatic proliferation") -AnnotationAssertion( "regulation of T-cell homeostatic proliferation") -AnnotationAssertion( "regulation of T-lymphocyte homeostatic proliferation") -AnnotationAssertion( "regulation of resting T cell proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046013") -AnnotationAssertion(rdfs:label "regulation of T cell homeostatic proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of T cell homeostatic proliferation) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents or reduces the rate or extent of resting T cell proliferation.") -AnnotationAssertion( "down regulation of T cell homeostatic proliferation") -AnnotationAssertion( "down-regulation of T cell homeostatic proliferation") -AnnotationAssertion( "downregulation of T cell homeostatic proliferation") -AnnotationAssertion( "negative regulation of T lymphocyte homeostatic proliferation") -AnnotationAssertion( "negative regulation of T-cell homeostatic proliferation") -AnnotationAssertion( "negative regulation of T-lymphocyte homeostatic proliferation") -AnnotationAssertion( "negative regulation of resting T cell proliferation") -AnnotationAssertion( "inhibition of T cell homeostatic proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046014") -AnnotationAssertion(rdfs:label "negative regulation of T cell homeostatic proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (ADP metabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways involving ADP, adenosine 5'-diphosphate.") -AnnotationAssertion( "ADP metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046031") -AnnotationAssertion(rdfs:label "ADP metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (ADP catabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways resulting in the breakdown of ADP, adenosine 5'-diphosphate.") -AnnotationAssertion( "ADP breakdown") -AnnotationAssertion( "ADP catabolism") -AnnotationAssertion( "ADP degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046032") -AnnotationAssertion(rdfs:label "ADP catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (ATP metabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways involving ATP, adenosine triphosphate, a universally important coenzyme and enzyme regulator.") -AnnotationAssertion( "ATP metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046034") -AnnotationAssertion(rdfs:label "ATP metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (adenine metabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways involving adenine, 6-aminopurine, one of the five main bases found in nucleic acids and a component of numerous important derivatives of its corresponding ribonucleoside, adenosine.") -AnnotationAssertion( "adenine metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046083") -AnnotationAssertion(rdfs:label "adenine metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (adenine biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways resulting in the formation of adenine, 6-aminopurine, one of the five main bases found in nucleic acids and a component of numerous important derivatives of its corresponding ribonucleoside, adenosine.") -AnnotationAssertion( "adenine anabolism") -AnnotationAssertion( "adenine biosynthesis") -AnnotationAssertion( "adenine formation") -AnnotationAssertion( "adenine synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046084") -AnnotationAssertion(rdfs:label "adenine biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (adenosine metabolic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways involving adenosine, adenine riboside, a ribonucleoside found widely distributed in cells of every type as the free nucleoside and in combination in nucleic acids and various nucleoside coenzymes.") -AnnotationAssertion( "adenosine metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046085") -AnnotationAssertion(rdfs:label "adenosine metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (adenosine biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways resulting in the formation of adenosine, adenine riboside, a ribonucleoside found widely distributed in cells of every type as the free nucleoside and in combination in nucleic acids and various nucleoside coenzymes.") -AnnotationAssertion( "adenosine anabolism") -AnnotationAssertion( "adenosine biosynthesis") -AnnotationAssertion( "adenosine formation") -AnnotationAssertion( "adenosine synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046086") -AnnotationAssertion(rdfs:label "adenosine biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (nucleobase biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways resulting in the formation of a nucleobase, a nitrogenous base that is a constituent of a nucleic acid.") -AnnotationAssertion( "nucleobase anabolism") -AnnotationAssertion( "nucleobase biosynthesis") -AnnotationAssertion( "nucleobase formation") -AnnotationAssertion( "nucleobase synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046112") -AnnotationAssertion(rdfs:label "nucleobase biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (nucleobase catabolic process) - -AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways resulting in the breakdown of a nucleobase, a nitrogenous base that is a constituent of a nucleic acid.") -AnnotationAssertion( "nucleobase breakdown") -AnnotationAssertion( "nucleobase catabolism") -AnnotationAssertion( "nucleobase degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046113") -AnnotationAssertion(rdfs:label "nucleobase catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (purine ribonucleoside metabolic process) - -AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways involving any ribonucleoside, a nucleoside in which purine base is linked to a ribose (beta-D-ribofuranose) molecule.") -AnnotationAssertion( "purine ribonucleoside metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046128") -AnnotationAssertion(rdfs:label "purine ribonucleoside metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (purine ribonucleoside biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways resulting in the formation of any purine ribonucleoside, a nucleoside in which purine base is linked to a ribose (beta-D-ribofuranose) molecule.") -AnnotationAssertion( "purine ribonucleoside anabolism") -AnnotationAssertion( "purine ribonucleoside biosynthesis") -AnnotationAssertion( "purine ribonucleoside formation") -AnnotationAssertion( "purine ribonucleoside synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046129") -AnnotationAssertion(rdfs:label "purine ribonucleoside biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (purine ribonucleoside catabolic process) - -AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways resulting in the breakdown of any purine ribonucleoside, a nucleoside in which purine base is linked to a ribose (beta-D-ribofuranose) molecule.") -AnnotationAssertion( "purine ribonucleoside breakdown") -AnnotationAssertion( "purine ribonucleoside catabolism") -AnnotationAssertion( "purine ribonucleoside degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046130") -AnnotationAssertion(rdfs:label "purine ribonucleoside catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (pigment biosynthetic process) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of a pigment, any general or particular coloring matter in living organisms, e.g. melanin.") -AnnotationAssertion( "pigment anabolism") -AnnotationAssertion( "pigment biosynthesis") -AnnotationAssertion( "pigment formation") -AnnotationAssertion( "pigment synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046148") -AnnotationAssertion(rdfs:label "pigment biosynthetic process") -SubClassOf( ) - -# Class: (alcohol catabolic process) - -AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways resulting in the breakdown of alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom.") -AnnotationAssertion( "alcohol breakdown") -AnnotationAssertion( "alcohol catabolism") -AnnotationAssertion( "alcohol degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046164") -AnnotationAssertion(rdfs:label "alcohol catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (alcohol biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways resulting in the formation of alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom.") -AnnotationAssertion( "alcohol anabolism") -AnnotationAssertion( "alcohol biosynthesis") -AnnotationAssertion( "alcohol formation") -AnnotationAssertion( "alcohol synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046165") -AnnotationAssertion(rdfs:label "alcohol biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - # Class: (aldehyde biosynthetic process) AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways resulting in the formation of aldehydes, any organic compound with the formula R-CH=O.") @@ -87352,170 +25646,11 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0046184") AnnotationAssertion(rdfs:label "aldehyde biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) -# Class: (aldehyde catabolic process) - -AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways resulting in the breakdown of aldehydes, any organic compound with the formula R-CH=O.") -AnnotationAssertion( "aldehyde breakdown") -AnnotationAssertion( "aldehyde catabolism") -AnnotationAssertion( "aldehyde degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046185") -AnnotationAssertion(rdfs:label "aldehyde catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (phenol-containing compound biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways resulting in the formation of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring.") -AnnotationAssertion( "phenol-containing compound anabolism") -AnnotationAssertion( "phenol-containing compound biosynthesis") -AnnotationAssertion( "phenol-containing compound formation") -AnnotationAssertion( "phenol-containing compound synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046189") -AnnotationAssertion(rdfs:label "phenol-containing compound biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (indolalkylamine biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:curators") "The chemical reactions and pathways resulting in the formation of indolalkylamines, indole or indole derivatives containing a primary, secondary, or tertiary amine group.") -AnnotationAssertion( "indolalkylamine anabolism") -AnnotationAssertion( "indolalkylamine biosynthesis") -AnnotationAssertion( "indolalkylamine formation") -AnnotationAssertion( "indolalkylamine synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046219") -AnnotationAssertion(rdfs:label "indolalkylamine biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (terpene biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways resulting in the formation of terpenes, any of a large group of hydrocarbons made up of isoprene units.") -AnnotationAssertion( "terpene anabolism") -AnnotationAssertion( "terpene biosynthesis") -AnnotationAssertion( "terpene formation") -AnnotationAssertion( "terpene synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046246") -AnnotationAssertion(rdfs:label "terpene biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (terpene catabolic process) - -AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways resulting in the breakdown of terpenes, any of a large group of hydrocarbons made up of isoprene units.") -AnnotationAssertion( "terpene breakdown") -AnnotationAssertion( "terpene catabolism") -AnnotationAssertion( "terpene degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046247") -AnnotationAssertion(rdfs:label "terpene catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (amino sugar catabolic process) - -AnnotationAssertion(Annotation( "GOC:curators") "The chemical reactions and pathways resulting in the breakdown of any amino sugar, sugars containing an amino group in place of a hydroxyl group.") -AnnotationAssertion( "amino sugar breakdown") -AnnotationAssertion( "amino sugar catabolism") -AnnotationAssertion( "amino sugar degradation") -AnnotationAssertion( "aminosaccharide catabolic process") -AnnotationAssertion( "aminosaccharide catabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046348") -AnnotationAssertion(rdfs:label "amino sugar catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (amino sugar biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:curators") "The chemical reactions and pathways resulting in the formation of any amino sugar, sugars containing an amino group in place of a hydroxyl group.") -AnnotationAssertion( "amino sugar anabolism") -AnnotationAssertion( "amino sugar biosynthesis") -AnnotationAssertion( "amino sugar formation") -AnnotationAssertion( "amino sugar synthesis") -AnnotationAssertion( "aminosaccharide biosynthesis") -AnnotationAssertion( "aminosaccharide biosynthetic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046349") -AnnotationAssertion(rdfs:label "amino sugar biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (butyrate biosynthetic process) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of butyrate, the anion of butyric acid.") -AnnotationAssertion( "GO:0043439") -AnnotationAssertion( "butanoic acid anabolism") -AnnotationAssertion( "butanoic acid biosynthesis") -AnnotationAssertion( "butanoic acid biosynthetic process") -AnnotationAssertion( "butanoic acid formation") -AnnotationAssertion( "butanoic acid synthesis") -AnnotationAssertion( "butyrate anabolism") -AnnotationAssertion( "butyrate biosynthesis") -AnnotationAssertion( "butyrate formation") -AnnotationAssertion( "butyrate synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046358") -AnnotationAssertion(rdfs:label "butyrate biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (butyrate catabolic process) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of butyrate, the anion of butyric acid.") -AnnotationAssertion( "GO:0043440") -AnnotationAssertion( "butanoic acid breakdown") -AnnotationAssertion( "butanoic acid catabolic process") -AnnotationAssertion( "butanoic acid catabolism") -AnnotationAssertion( "butanoic acid degradation") -AnnotationAssertion( "butyrate breakdown") -AnnotationAssertion( "butyrate catabolism") -AnnotationAssertion( "butyrate degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046359") -AnnotationAssertion(rdfs:label "butyrate catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (monosaccharide biosynthetic process) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of monosaccharides, polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms.") -AnnotationAssertion( "monosaccharide anabolism") -AnnotationAssertion( "monosaccharide biosynthesis") -AnnotationAssertion( "monosaccharide formation") -AnnotationAssertion( "monosaccharide synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046364") -AnnotationAssertion(rdfs:label "monosaccharide biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (monosaccharide catabolic process) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of monosaccharides, polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms.") -AnnotationAssertion( "monosaccharide breakdown") -AnnotationAssertion( "monosaccharide catabolism") -AnnotationAssertion( "monosaccharide degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046365") -AnnotationAssertion(rdfs:label "monosaccharide catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (ribose phosphate biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways resulting in the formation of ribose phosphate, any phosphorylated ribose sugar.") -AnnotationAssertion( "ribose phosphate anabolism") -AnnotationAssertion( "ribose phosphate biosynthesis") -AnnotationAssertion( "ribose phosphate formation") -AnnotationAssertion( "ribose phosphate synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046390") -AnnotationAssertion(rdfs:label "ribose phosphate biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (carboxylic acid biosynthetic process) AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of carboxylic acids, any organic acid containing one or more carboxyl (-COOH) groups.") @@ -87526,124 +25661,9 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0046394") AnnotationAssertion(rdfs:label "carboxylic acid biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) -# Class: (carboxylic acid catabolic process) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of carboxylic acids, any organic acid containing one or more carboxyl (-COOH) groups.") -AnnotationAssertion( "carboxylic acid breakdown") -AnnotationAssertion( "carboxylic acid catabolism") -AnnotationAssertion( "carboxylic acid degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046395") -AnnotationAssertion(rdfs:label "carboxylic acid catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (D-amino acid metabolic process) - -AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:jsg") "The chemical reactions and pathways involving D-amino acids, the D-enantiomers of amino acids.") -AnnotationAssertion( "D-amino acid metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046416") -AnnotationAssertion(rdfs:label "D-amino acid metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (organophosphate catabolic process) - -AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways resulting in the breakdown of organophosphates, any phosphate-containing organic compound.") -AnnotationAssertion( "organophosphate breakdown") -AnnotationAssertion( "organophosphate catabolism") -AnnotationAssertion( "organophosphate degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046434") -AnnotationAssertion(rdfs:label "organophosphate catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (D-amino acid biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:jsg") "The chemical reactions and pathways resulting in the formation of D-amino acids, the D-enantiomers of amino acids.") -AnnotationAssertion( "D-amino acid anabolism") -AnnotationAssertion( "D-amino acid biosynthesis") -AnnotationAssertion( "D-amino acid formation") -AnnotationAssertion( "D-amino acid synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046437") -AnnotationAssertion(rdfs:label "D-amino acid biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (short-chain fatty acid metabolic process) - -AnnotationAssertion(Annotation( "Wikipedia:Fatty_acid_metabolism") "The chemical reactions and pathways involving a fatty acid with an aliphatic tail of less than 6 carbons.") -AnnotationAssertion( "short-chain fatty acid metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046459") -AnnotationAssertion(rdfs:label "short-chain fatty acid metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (membrane lipid catabolic process) - -AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways resulting in the breakdown of membrane lipids, any lipid found in or associated with a biological membrane.") -AnnotationAssertion(Annotation( "GOC:tb") "membrane lipid peroxidation") -AnnotationAssertion( "membrane lipid breakdown") -AnnotationAssertion( "membrane lipid catabolism") -AnnotationAssertion( "membrane lipid degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046466") -AnnotationAssertion(rdfs:label "membrane lipid catabolic process") -SubClassOf( ) -SubClassOf( ) - -# Class: (membrane lipid biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways resulting in the formation of membrane lipids, any lipid found in or associated with a biological membrane.") -AnnotationAssertion( "membrane lipid anabolism") -AnnotationAssertion( "membrane lipid biosynthesis") -AnnotationAssertion( "membrane lipid formation") -AnnotationAssertion( "membrane lipid synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046467") -AnnotationAssertion(rdfs:label "membrane lipid biosynthetic process") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (glycosylceramide biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways resulting in the formation of glycosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of a monosaccharide (or derivative) by a ceramide group.") -AnnotationAssertion( "glycosylceramide anabolism") -AnnotationAssertion( "glycosylceramide biosynthesis") -AnnotationAssertion( "glycosylceramide formation") -AnnotationAssertion( "glycosylceramide synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046476") -AnnotationAssertion(rdfs:label "glycosylceramide biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (glycosylceramide catabolic process) - -AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways resulting in the breakdown of glycosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of a monosaccharide (or derivative) by a ceramide group.") -AnnotationAssertion( "glycosylceramide breakdown") -AnnotationAssertion( "glycosylceramide catabolism") -AnnotationAssertion( "glycosylceramide degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046477") -AnnotationAssertion(rdfs:label "glycosylceramide catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (glycosphingolipid catabolic process) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of glycosphingolipid, a compound with residues of sphingoid and at least one monosaccharide.") -AnnotationAssertion( "glycosphingolipid breakdown") -AnnotationAssertion( "glycosphingolipid catabolism") -AnnotationAssertion( "glycosphingolipid degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046479") -AnnotationAssertion(rdfs:label "glycosphingolipid catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (heterocycle metabolic process) AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings).") @@ -87652,92 +25672,8 @@ AnnotationAssertion( "GO:0046483") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "heterocycle metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (ceramide biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways resulting in the formation of ceramides, any N-acylated sphingoid.") -AnnotationAssertion( "ceramide anabolism") -AnnotationAssertion( "ceramide biosynthesis") -AnnotationAssertion( "ceramide formation") -AnnotationAssertion( "ceramide synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046513") -AnnotationAssertion(rdfs:label "ceramide biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (ceramide catabolic process) - -AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways resulting in the breakdown of ceramides, any N-acetylated sphingoid.") -AnnotationAssertion( "ceramide breakdown") -AnnotationAssertion( "ceramide catabolism") -AnnotationAssertion( "ceramide degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046514") -AnnotationAssertion(rdfs:label "ceramide catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (photoreceptor cell differentiation) - -AnnotationAssertion(Annotation( "GOC:ai") Annotation( "ISBN:0198506732") "The specialization of organization of a photoreceptor, a cell that responds to incident electromagnetic radiation, particularly visible light. An example of this process is found in Drosophila melanogaster.") -AnnotationAssertion( "GO:0007467") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046530") -AnnotationAssertion(rdfs:label "photoreceptor cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of photoreceptor cell differentiation) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of photoreceptor cell differentiation. An example of this process is found in Drosophila melanogaster.") -AnnotationAssertion( "GO:0045673") -AnnotationAssertion( "regulation of photoreceptor differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046532") -AnnotationAssertion(rdfs:label "regulation of photoreceptor cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of photoreceptor cell differentiation) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of photoreceptor cell differentiation. An example of this process is found in Drosophila melanogaster.") -AnnotationAssertion( "GO:0045674") -AnnotationAssertion( "down regulation of photoreceptor cell differentiation") -AnnotationAssertion( "down regulation of photoreceptor differentiation") -AnnotationAssertion( "down-regulation of photoreceptor cell differentiation") -AnnotationAssertion( "down-regulation of photoreceptor differentiation") -AnnotationAssertion( "downregulation of photoreceptor cell differentiation") -AnnotationAssertion( "downregulation of photoreceptor differentiation") -AnnotationAssertion( "negative regulation of photoreceptor differentiation") -AnnotationAssertion( "inhibition of photoreceptor cell differentiation") -AnnotationAssertion( "inhibition of photoreceptor differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046533") -AnnotationAssertion(rdfs:label "negative regulation of photoreceptor cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (positive regulation of photoreceptor cell differentiation) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of photoreceptor cell differentiation. An example of this process is found in Drosophila melanogaster.") -AnnotationAssertion( "GO:0045675") -AnnotationAssertion( "positive regulation of photoreceptor differentiation") -AnnotationAssertion( "up regulation of photoreceptor cell differentiation") -AnnotationAssertion( "up regulation of photoreceptor differentiation") -AnnotationAssertion( "up-regulation of photoreceptor cell differentiation") -AnnotationAssertion( "up-regulation of photoreceptor differentiation") -AnnotationAssertion( "upregulation of photoreceptor cell differentiation") -AnnotationAssertion( "upregulation of photoreceptor differentiation") -AnnotationAssertion( "activation of photoreceptor cell differentiation") -AnnotationAssertion( "activation of photoreceptor differentiation") -AnnotationAssertion( "stimulation of photoreceptor cell differentiation") -AnnotationAssertion( "stimulation of photoreceptor differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046534") -AnnotationAssertion(rdfs:label "positive regulation of photoreceptor cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - # Class: (saliva secretion) AnnotationAssertion(Annotation( "GOC:curators") Annotation( "UBERON:0001836") "The regulated release of saliva from the salivary glands. In man, the saliva is a turbid and slightly viscous fluid, generally of an alkaline reaction, and is secreted by the parotid, submaxillary, and sublingual glands. In the mouth the saliva is mixed with the secretion from the buccal glands. In man and many animals, saliva is an important digestive fluid on account of the presence of the peculiar enzyme, ptyalin.") @@ -87759,123 +25695,12 @@ AnnotationAssertion(rdfs:label "deve SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (development of primary male sexual characteristics) - -AnnotationAssertion(Annotation( "GOC:ai") "The process whose specific outcome is the progression of the primary male sexual characteristics over time, from their formation to the mature structures. The primary male sexual characteristics are the testes, and they develop in response to sex hormone secretion.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046546") -AnnotationAssertion(rdfs:label "development of primary male sexual characteristics") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (retinal rod cell development) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "Development of a rod cell, one of the sensory cells in the eye that reacts to the presence of light. Rod cells contain the photopigment rhodopsin or porphyropsin and are responsible for vision in dim light.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046548") -AnnotationAssertion(rdfs:label "retinal rod cell development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (retinal cone cell development) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "Development of a cone cell, one of the sensory cells in the eye that reacts to the presence of light. Cone cells contain the photopigment iodopsin or cyanopsin and are responsible for photopic (daylight) vision.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046549") -AnnotationAssertion(rdfs:label "retinal cone cell development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (regulation of organ growth) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:tb") "Any process that modulates the frequency, rate or extent of growth of an organ of an organism.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046620") -AnnotationAssertion(rdfs:label "regulation of organ growth") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of organ growth) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:tb") "Any process that stops, prevents, or reduces the frequency, rate or extent of growth of an organ of an organism.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046621") -AnnotationAssertion(rdfs:label "negative regulation of organ growth") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of organ growth) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:tb") "Any process that activates or increases the frequency, rate or extent of growth of an organ of an organism.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046622") -AnnotationAssertion(rdfs:label "positive regulation of organ growth") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (sphingolipid transporter activity) - -AnnotationAssertion(Annotation( "GOC:ai") Annotation( "ISBN:0198506732") "Enables the directed movement of sphingolipids into, out of or within a cell, or between cells. Sphingolipids are a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).") -AnnotationAssertion(Annotation(rdfs:label "SPNS2 transports S1P from cytosol to extracellular region") "Reactome:R-HSA-9695890") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0046624") -AnnotationAssertion(rdfs:label "sphingolipid transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (sphingolipid binding) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "Binding to a sphingolipid, a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0046625") -AnnotationAssertion(rdfs:label "sphingolipid binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of insulin receptor signaling pathway) - -AnnotationAssertion(Annotation( "GOC:bf") "Any process that modulates the frequency, rate or extent of insulin receptor signaling.") -AnnotationAssertion( "regulation of insulin receptor signalling pathway") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046626") -AnnotationAssertion(rdfs:label "regulation of insulin receptor signaling pathway") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - -# Class: (negative regulation of insulin receptor signaling pathway) - -AnnotationAssertion(Annotation( "GOC:bf") "Any process that stops, prevents, or reduces the frequency, rate or extent of insulin receptor signaling.") -AnnotationAssertion( "down regulation of insulin receptor signaling pathway") -AnnotationAssertion( "down-regulation of insulin receptor signaling pathway") -AnnotationAssertion( "downregulation of insulin receptor signaling pathway") -AnnotationAssertion( "negative regulation of insulin receptor signalling pathway") -AnnotationAssertion( "inhibition of insulin receptor signaling pathway") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046627") -AnnotationAssertion(rdfs:label "negative regulation of insulin receptor signaling pathway") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of insulin receptor signaling pathway) - -AnnotationAssertion(Annotation( "GOC:bf") "Any process that increases the frequency, rate or extent of insulin receptor signaling.") -AnnotationAssertion( "positive regulation of insulin receptor signalling pathway") -AnnotationAssertion( "up regulation of insulin receptor signaling pathway") -AnnotationAssertion( "up-regulation of insulin receptor signaling pathway") -AnnotationAssertion( "upregulation of insulin receptor signaling pathway") -AnnotationAssertion( "activation of insulin receptor signaling pathway") -AnnotationAssertion( "stimulation of insulin receptor signaling pathway") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046628") -AnnotationAssertion(rdfs:label "positive regulation of insulin receptor signaling pathway") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - # Class: (lymphocyte activation) AnnotationAssertion(Annotation( "GOC:mgi_curators") Annotation( "ISBN:0781735149") "A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor.") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0046649") AnnotationAssertion(rdfs:label "lymphocyte activation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) # Class: (lymphocyte proliferation) @@ -87884,7 +25709,6 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:0046651") AnnotationAssertion(rdfs:label "lymphocyte proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) @@ -87897,148 +25721,6 @@ AnnotationAssertion(rdfs:label "fema SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (male sex differentiation) - -AnnotationAssertion(Annotation( "GOC:bf") "The establishment of the sex of a male organism by physical differentiation.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046661") -AnnotationAssertion(rdfs:label "male sex differentiation") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (retinal cell programmed cell death) - -AnnotationAssertion(Annotation( "GOC:bf") "Programmed cell death that occurs in the developing retina.") -AnnotationAssertion( "programmed cell death, retina cells") -AnnotationAssertion( "programmed cell death, retinal cells") -AnnotationAssertion( "retina cell programmed cell death") -AnnotationAssertion( "retina programmed cell death") -AnnotationAssertion( "retinal programmed cell death") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046666") -AnnotationAssertion(rdfs:label "retinal cell programmed cell death") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (compound eye retinal cell programmed cell death) - -AnnotationAssertion(Annotation( "PMID:12006672") "Programmed cell death that occurs in the retina to remove excess cells between ommatidia, thus resulting in a hexagonal lattice, precise with respect to cell number and position surrounding each ommatidium.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046667") -AnnotationAssertion(rdfs:label "compound eye retinal cell programmed cell death") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (regulation of retinal cell programmed cell death) - -AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:tb") "Any process that modulates the frequency, rate or extent of programmed cell death that occurs in the retina.") -AnnotationAssertion(Annotation( "GOC:tb") "regulation of retinal programmed cell death") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046668") -AnnotationAssertion(rdfs:label "regulation of retinal cell programmed cell death") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of compound eye retinal cell programmed cell death) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of programmed cell death that occurs in the compound eye retina.") -AnnotationAssertion( "regulation of retinal cell programmed cell death") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046669") -AnnotationAssertion(rdfs:label "regulation of compound eye retinal cell programmed cell death") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of retinal cell programmed cell death) - -AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:tb") "Any process that activates or increases the frequency, rate or extent of programmed cell death that occurs in the retina.") -AnnotationAssertion(Annotation( "GOC:tb") "positive regulation of retinal programmed cell death") -AnnotationAssertion( "up regulation of retinal programmed cell death") -AnnotationAssertion( "up-regulation of retinal programmed cell death") -AnnotationAssertion( "upregulation of retinal programmed cell death") -AnnotationAssertion( "activation of retinal programmed cell death") -AnnotationAssertion( "stimulation of retinal programmed cell death") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046670") -AnnotationAssertion(rdfs:label "positive regulation of retinal cell programmed cell death") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of retinal cell programmed cell death) - -AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:tb") "Any process that stops, prevents, or reduces the frequency, rate or extent of programmed cell death that occurs in the retina.") -AnnotationAssertion( "down regulation of retinal programmed cell death") -AnnotationAssertion( "down-regulation of retinal programmed cell death") -AnnotationAssertion( "downregulation of retinal programmed cell death") -AnnotationAssertion(Annotation( "GOC:tb") "negative regulation of retinal programmed cell death") -AnnotationAssertion( "inhibition of retinal programmed cell death") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046671") -AnnotationAssertion(rdfs:label "negative regulation of retinal cell programmed cell death") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of compound eye retinal cell programmed cell death) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of programmed cell death that occurs in the compound eye retina.") -AnnotationAssertion( "activation of retinal cell programmed cell death") -AnnotationAssertion( "positive regulation of retinal cell programmed cell death") -AnnotationAssertion( "stimulation of retinal cell programmed cell death") -AnnotationAssertion( "up regulation of retinal cell programmed cell death") -AnnotationAssertion( "up-regulation of retinal cell programmed cell death") -AnnotationAssertion( "upregulation of retinal cell programmed cell death") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046672") -AnnotationAssertion(rdfs:label "positive regulation of compound eye retinal cell programmed cell death") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of compound eye retinal cell programmed cell death) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of programmed cell death that occurs in the compound eye retina.") -AnnotationAssertion( "down regulation of retinal cell programmed cell death") -AnnotationAssertion( "down-regulation of retinal cell programmed cell death") -AnnotationAssertion( "downregulation of retinal cell programmed cell death") -AnnotationAssertion( "inhibition of retinal cell programmed cell death") -AnnotationAssertion( "negative regulation of retina cell programmed cell death") -AnnotationAssertion( "negative regulation of retinal cell programmed cell death") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046673") -AnnotationAssertion(rdfs:label "negative regulation of compound eye retinal cell programmed cell death") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of insulin secretion) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of insulin.") -AnnotationAssertion( "down regulation of insulin secretion") -AnnotationAssertion( "down-regulation of insulin secretion") -AnnotationAssertion( "downregulation of insulin secretion") -AnnotationAssertion( "inhibition of insulin secretion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046676") -AnnotationAssertion(rdfs:label "negative regulation of insulin secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (response to carbamate) - -AnnotationAssertion(Annotation( "ISBN:0721662544") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbamate stimulus. Carbamates are a group of insecticides and parasiticides that act by inhibiting cholinesterase.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "carbamate resistance") -AnnotationAssertion( "carbamate susceptibility/resistance") -AnnotationAssertion( "GO:0046681") -AnnotationAssertion(rdfs:label "response to carbamate") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (response to organophosphorus) - -AnnotationAssertion(Annotation( "ISBN:0721662544") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organophosphorus stimulus. Organophosphorus is a compound containing phosphorus bound to an organic molecule; several organophosphorus compounds are used as insecticides, and they are highly toxic cholinesterase inhibitors.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "organophosphorus resistance") -AnnotationAssertion( "organophosphorus susceptibility/resistance") -AnnotationAssertion( "GO:0046683") -AnnotationAssertion(rdfs:label "response to organophosphorus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (sperm competition) AnnotationAssertion(Annotation( "PMID:10885514") "Any process that contributes to the success of sperm fertilization in multiply-mated females.") @@ -88051,33 +25733,6 @@ SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (heterocycle catabolic process) - -AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways resulting in the breakdown of heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings).") -AnnotationAssertion( "heterocycle breakdown") -AnnotationAssertion( "heterocycle catabolism") -AnnotationAssertion( "heterocycle degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046700") -AnnotationAssertion(rdfs:label "heterocycle catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (muscle cell cellular homeostasis) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "PMID:3091429") Annotation( "PMID:7781901") "The cellular homeostatic process that preserves a muscle cell in a stable functional or structural state.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/24218"^^xsd:anyURI) -AnnotationAssertion( ) -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "muscle fiber maintenance") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") "muscle homeostasis") -AnnotationAssertion( "GO:0046716") -AnnotationAssertion(rdfs:label "muscle cell cellular homeostasis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) -DisjointClasses( ObjectSomeValuesFrom( )) - # Class: (acid secretion) AnnotationAssertion(Annotation( "GOC:ai") "The controlled release of acid by a cell or a tissue.") @@ -88086,344 +25741,6 @@ AnnotationAssertion( "acid secretion") SubClassOf( ) -# Class: (formic acid secretion) - -AnnotationAssertion(Annotation( "GOC:ai") "The controlled release of formic acid, HCOOH, by a cell or a tissue.") -AnnotationAssertion( "formate secretion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046721") -AnnotationAssertion(rdfs:label "formic acid secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (microtubule polymerization) - -AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:go_curators") "The addition of tubulin heterodimers to one or both ends of a microtubule.") -AnnotationAssertion( "microtubule assembly") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "microtubule formation") -AnnotationAssertion( "GO:0046785") -AnnotationAssertion(rdfs:label "microtubule polymerization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (regulation of nucleocytoplasmic transport) - -AnnotationAssertion(Annotation( "GOC:bf") "Any process that modulates the frequency, rate or extent of the directed movement of substances between the nucleus and the cytoplasm.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046822") -AnnotationAssertion(rdfs:label "regulation of nucleocytoplasmic transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of nucleocytoplasmic transport) - -AnnotationAssertion(Annotation( "GOC:bf") "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances between the cytoplasm and the nucleus.") -AnnotationAssertion( "down regulation of nucleocytoplasmic transport") -AnnotationAssertion( "down-regulation of nucleocytoplasmic transport") -AnnotationAssertion( "downregulation of nucleocytoplasmic transport") -AnnotationAssertion( "inhibition of nucleocytoplasmic transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046823") -AnnotationAssertion(rdfs:label "negative regulation of nucleocytoplasmic transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of nucleocytoplasmic transport) - -AnnotationAssertion(Annotation( "GOC:bf") "Any process that activates or increases the frequency, rate or extent of the directed movement of substances between the nucleus and the cytoplasm.") -AnnotationAssertion( "up regulation of nucleocytoplasmic transport") -AnnotationAssertion( "up-regulation of nucleocytoplasmic transport") -AnnotationAssertion( "upregulation of nucleocytoplasmic transport") -AnnotationAssertion( "activation of nucleocytoplasmic transport") -AnnotationAssertion( "stimulation of nucleocytoplasmic transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046824") -AnnotationAssertion(rdfs:label "positive regulation of nucleocytoplasmic transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of protein export from nucleus) - -AnnotationAssertion(Annotation( "GOC:bf") "Any process that modulates the frequency, rate or extent of the directed movement of proteins from the nucleus to the cytoplasm.") -AnnotationAssertion( "regulation of protein export from cell nucleus") -AnnotationAssertion( "regulation of protein export out of nucleus") -AnnotationAssertion( "regulation of protein transport from nucleus to cytoplasm") -AnnotationAssertion( "regulation of protein-nucleus export") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046825") -AnnotationAssertion(rdfs:label "regulation of protein export from nucleus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of protein export from nucleus) - -AnnotationAssertion(Annotation( "GOC:bf") "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of proteins from the nucleus into the cytoplasm.") -AnnotationAssertion( "down regulation of protein export from nucleus") -AnnotationAssertion( "down-regulation of protein export from nucleus") -AnnotationAssertion( "downregulation of protein export from nucleus") -AnnotationAssertion( "negative regulation of protein export from cell nucleus") -AnnotationAssertion( "negative regulation of protein export out of nucleus") -AnnotationAssertion( "negative regulation of protein transport from nucleus to cytoplasm") -AnnotationAssertion( "negative regulation of protein-nucleus export") -AnnotationAssertion( "inhibition of protein export from nucleus") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046826") -AnnotationAssertion(rdfs:label "negative regulation of protein export from nucleus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (positive regulation of protein export from nucleus) - -AnnotationAssertion(Annotation( "GOC:bf") "Any process that activates or increases the frequency, rate or extent of directed movement of proteins from the nucleus into the cytoplasm.") -AnnotationAssertion( "positive regulation of protein export from cell nucleus") -AnnotationAssertion( "positive regulation of protein export out of nucleus") -AnnotationAssertion( "positive regulation of protein transport from nucleus to cytoplasm") -AnnotationAssertion( "positive regulation of protein-nucleus export") -AnnotationAssertion( "up regulation of protein export from nucleus") -AnnotationAssertion( "up-regulation of protein export from nucleus") -AnnotationAssertion( "upregulation of protein export from nucleus") -AnnotationAssertion( "activation of protein export from nucleus") -AnnotationAssertion( "stimulation of protein export from nucleus") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046827") -AnnotationAssertion(rdfs:label "positive regulation of protein export from nucleus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of RNA import into nucleus) - -AnnotationAssertion(Annotation( "GOC:bf") "Any process that modulates the frequency, rate or extent of movement of RNA from the cytoplasm to the nucleus.") -AnnotationAssertion( "regulation of RNA import into cell nucleus") -AnnotationAssertion( "regulation of RNA transport from cytoplasm to nucleus") -AnnotationAssertion( "regulation of RNA-nucleus import") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046828") -AnnotationAssertion(rdfs:label "regulation of RNA import into nucleus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of RNA import into nucleus) - -AnnotationAssertion(Annotation( "GOC:bf") "Any process that stops, prevents, or reduces the frequency, rate or extent of the movement of RNA from the cytoplasm into the nucleus.") -AnnotationAssertion( "down regulation of RNA import into nucleus") -AnnotationAssertion( "down-regulation of RNA import into nucleus") -AnnotationAssertion( "downregulation of RNA import into nucleus") -AnnotationAssertion( "negative regulation of RNA import into cell nucleus") -AnnotationAssertion( "negative regulation of RNA transport from cytoplasm to nucleus") -AnnotationAssertion( "negative regulation of RNA-nucleus import") -AnnotationAssertion( "inhibition of RNA import into nucleus") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046829") -AnnotationAssertion(rdfs:label "negative regulation of RNA import into nucleus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of RNA import into nucleus) - -AnnotationAssertion(Annotation( "GOC:bf") "Any process that activates or increases the frequency, rate or extent of movement of RNA from the cytoplasm into the nucleus.") -AnnotationAssertion( "positive regulation of RNA import into cell nucleus") -AnnotationAssertion( "positive regulation of RNA transport from cytoplasm to nucleus") -AnnotationAssertion( "positive regulation of RNA-nucleus import") -AnnotationAssertion( "up regulation of RNA import into nucleus") -AnnotationAssertion( "up-regulation of RNA import into nucleus") -AnnotationAssertion( "upregulation of RNA import into nucleus") -AnnotationAssertion( "activation of RNA import into nucleus") -AnnotationAssertion( "stimulation of RNA import into nucleus") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046830") -AnnotationAssertion(rdfs:label "positive regulation of RNA import into nucleus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of RNA export from nucleus) - -AnnotationAssertion(Annotation( "GOC:bf") "Any process that modulates the frequency, rate or extent of the directed movement of RNA from the nucleus to the cytoplasm.") -AnnotationAssertion( "regulation of RNA export from cell nucleus") -AnnotationAssertion( "regulation of RNA export out of nucleus") -AnnotationAssertion( "regulation of RNA transport from nucleus to cytoplasm") -AnnotationAssertion( "regulation of RNA-nucleus export") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046831") -AnnotationAssertion(rdfs:label "regulation of RNA export from nucleus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of RNA export from nucleus) - -AnnotationAssertion(Annotation( "GOC:bf") "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of RNA from the nucleus into the cytoplasm.") -AnnotationAssertion( "down regulation of RNA export from nucleus") -AnnotationAssertion( "down-regulation of RNA export from nucleus") -AnnotationAssertion( "downregulation of RNA export from nucleus") -AnnotationAssertion( "negative regulation of RNA export from cell nucleus") -AnnotationAssertion( "negative regulation of RNA export out of nucleus") -AnnotationAssertion( "negative regulation of RNA transport from nucleus to cytoplasm") -AnnotationAssertion( "negative regulation of RNA-nucleus export") -AnnotationAssertion( "inhibition of RNA export from nucleus") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046832") -AnnotationAssertion(rdfs:label "negative regulation of RNA export from nucleus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of RNA export from nucleus) - -AnnotationAssertion(Annotation( "GOC:bf") "Any process that activates or increases the frequency, rate or extent of directed movement of RNA from the nucleus into the cytoplasm.") -AnnotationAssertion( "positive regulation of RNA export from cell nucleus") -AnnotationAssertion( "positive regulation of RNA export out of nucleus") -AnnotationAssertion( "positive regulation of RNA transport from nucleus to cytoplasm") -AnnotationAssertion( "positive regulation of RNA-nucleus export") -AnnotationAssertion( "up regulation of RNA export from nucleus") -AnnotationAssertion( "up-regulation of RNA export from nucleus") -AnnotationAssertion( "upregulation of RNA export from nucleus") -AnnotationAssertion( "activation of RNA export from nucleus") -AnnotationAssertion( "stimulation of RNA export from nucleus") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046833") -AnnotationAssertion(rdfs:label "positive regulation of RNA export from nucleus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (glycolipid transport) - -AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of glycolipids, compounds containing (usually) 1-4 linked monosaccharide residues joined by a glycosyl linkage to a lipid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046836") -AnnotationAssertion(rdfs:label "glycolipid transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (hydroxyapatite binding) - -AnnotationAssertion(Annotation( "PMID:2438276") "Binding to hydroxyapatite, the calcium phosphate mineral of formula Ca10(PO4)6(OH)2 found both in rocks of nonorganic origin and as a component of bone and dentin.") -AnnotationAssertion(Annotation( "GOC:vk") "hydroxylapatite binding") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0046848") -AnnotationAssertion(rdfs:label "hydroxyapatite binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (bone remodeling) - -AnnotationAssertion(Annotation( "GOC:curators") "The continuous turnover of bone matrix and mineral that involves first, an increase in resorption (osteoclastic activity) and later, reactive bone formation (osteoblastic activity). The process of bone remodeling takes place in the adult skeleton at discrete foci. The process ensures the mechanical integrity of the skeleton throughout life and plays an important role in calcium homeostasis. An imbalance in the regulation of bone resorption and bone formation results in many of the metabolic bone diseases, such as osteoporosis.") -AnnotationAssertion( "Wikipedia:Bone_remodeling") -AnnotationAssertion( "bone remodelling") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046849") -AnnotationAssertion(rdfs:label "bone remodeling") -SubClassOf( ) - -# Class: (regulation of bone remodeling) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of bone remodeling, the processes of bone formation and resorption that combine to maintain skeletal integrity.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046850") -AnnotationAssertion(rdfs:label "regulation of bone remodeling") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of bone remodeling) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of bone remodeling.") -AnnotationAssertion( "down regulation of bone remodeling") -AnnotationAssertion( "down-regulation of bone remodeling") -AnnotationAssertion( "downregulation of bone remodeling") -AnnotationAssertion( "inhibition of bone remodeling") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046851") -AnnotationAssertion(rdfs:label "negative regulation of bone remodeling") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of bone remodeling) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of bone remodeling.") -AnnotationAssertion( "up regulation of bone remodeling") -AnnotationAssertion( "up-regulation of bone remodeling") -AnnotationAssertion( "upregulation of bone remodeling") -AnnotationAssertion( "activation of bone remodeling") -AnnotationAssertion( "stimulation of bone remodeling") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046852") -AnnotationAssertion(rdfs:label "positive regulation of bone remodeling") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (isoprenoid transport) - -AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of isoprenoids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Isoprenoids comprise a group of compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046864") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "isoprenoid transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (terpenoid transport) - -AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of terpenoids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Terpenoids are a class of compounds characterized by an isoprenoid chemical structure and include derivatives with various functional groups.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046865") -AnnotationAssertion(rdfs:label "terpenoid transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (tetraterpenoid transport) - -AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of tetraterpenoids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Tetraterpenoids are terpenoids with eight isoprene units.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046866") -AnnotationAssertion(rdfs:label "tetraterpenoid transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (carotenoid transport) - -AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of carotenoids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carotenoids are tetraterpenoid compounds in which two units of 4 isoprenoid residues joined head-to-tail are themselves joined tail-to-tail.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046867") -AnnotationAssertion(rdfs:label "carotenoid transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (metal ion binding) - -AnnotationAssertion(Annotation( "GOC:ai") "Binding to a metal ion.") -AnnotationAssertion( "metal binding") -AnnotationAssertion( "heavy metal binding") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0046872") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "metal ion binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (metal ion transmembrane transporter activity) - -AnnotationAssertion(Annotation( "GOC:ai") "Enables the transfer of metal ions from one side of a membrane to the other.") -AnnotationAssertion( "heavy metal ion porter activity") -AnnotationAssertion( "heavy metal ion transporter activity") -AnnotationAssertion( "heavy metal ion:hydrogen symporter activity") -AnnotationAssertion( "heavy metal-exporting ATPase activity") -AnnotationAssertion( "high affinity metal ion uptake transporter activity") -AnnotationAssertion( "low affinity metal ion uptake transporter activity") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0046873") -AnnotationAssertion(rdfs:label "metal ion transmembrane transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (regulation of saliva secretion) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of the regulated release of saliva from a cell or a tissue.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046877") -AnnotationAssertion(rdfs:label "regulation of saliva secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of saliva secretion) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of the regulated release of saliva.") -AnnotationAssertion( "up regulation of saliva secretion") -AnnotationAssertion( "up-regulation of saliva secretion") -AnnotationAssertion( "upregulation of saliva secretion") -AnnotationAssertion( "activation of saliva secretion") -AnnotationAssertion( "stimulation of saliva secretion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046878") -AnnotationAssertion(rdfs:label "positive regulation of saliva secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - # Class: (hormone secretion) AnnotationAssertion(Annotation( "ISBN:0198506732") "The regulated release of hormones, substances with a specific regulatory effect on a particular organ or group of cells.") @@ -88439,115 +25756,11 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:0046883") AnnotationAssertion(rdfs:label "regulation of hormone secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) -# Class: (regulation of hormone biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hormones.") -AnnotationAssertion( "regulation of hormone anabolism") -AnnotationAssertion( "regulation of hormone biosynthesis") -AnnotationAssertion( "regulation of hormone formation") -AnnotationAssertion( "regulation of hormone synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046885") -AnnotationAssertion(rdfs:label "regulation of hormone biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of hormone biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hormones.") -AnnotationAssertion( "positive regulation of hormone anabolism") -AnnotationAssertion( "positive regulation of hormone biosynthesis") -AnnotationAssertion( "positive regulation of hormone formation") -AnnotationAssertion( "positive regulation of hormone synthesis") -AnnotationAssertion( "up regulation of hormone biosynthetic process") -AnnotationAssertion( "up-regulation of hormone biosynthetic process") -AnnotationAssertion( "upregulation of hormone biosynthetic process") -AnnotationAssertion( "activation of hormone biosynthetic process") -AnnotationAssertion( "stimulation of hormone biosynthetic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046886") -AnnotationAssertion(rdfs:label "positive regulation of hormone biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of hormone secretion) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of the regulated release of a hormone from a cell.") -AnnotationAssertion( "up regulation of hormone secretion") -AnnotationAssertion( "up-regulation of hormone secretion") -AnnotationAssertion( "upregulation of hormone secretion") -AnnotationAssertion( "activation of hormone secretion") -AnnotationAssertion( "stimulation of hormone secretion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046887") -AnnotationAssertion(rdfs:label "positive regulation of hormone secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of hormone secretion) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a hormone from a cell.") -AnnotationAssertion( "down regulation of hormone secretion") -AnnotationAssertion( "down-regulation of hormone secretion") -AnnotationAssertion( "downregulation of hormone secretion") -AnnotationAssertion( "inhibition of hormone secretion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046888") -AnnotationAssertion(rdfs:label "negative regulation of hormone secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of lipid biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids.") -AnnotationAssertion( "positive regulation of lipid anabolism") -AnnotationAssertion( "positive regulation of lipid biosynthesis") -AnnotationAssertion( "positive regulation of lipid formation") -AnnotationAssertion( "positive regulation of lipid synthesis") -AnnotationAssertion(Annotation( "GOC:sl") "positive regulation of lipogenesis") -AnnotationAssertion( "up regulation of lipid biosynthetic process") -AnnotationAssertion( "up-regulation of lipid biosynthetic process") -AnnotationAssertion( "upregulation of lipid biosynthetic process") -AnnotationAssertion( "activation of lipid biosynthetic process") -AnnotationAssertion( "stimulation of lipid biosynthetic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046889") -AnnotationAssertion(rdfs:label "positive regulation of lipid biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of lipid biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids.") -AnnotationAssertion( "regulation of lipid anabolism") -AnnotationAssertion( "regulation of lipid biosynthesis") -AnnotationAssertion( "regulation of lipid formation") -AnnotationAssertion( "regulation of lipid synthesis") -AnnotationAssertion(Annotation( "GOC:sl") "regulation of lipogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046890") -AnnotationAssertion(rdfs:label "regulation of lipid biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - # Class: (secretion) AnnotationAssertion(Annotation( "GOC:ai") "The controlled release of a substance by a cell or a tissue.") @@ -88557,341 +25770,12 @@ AnnotationAssertion( "secretion") SubClassOf( ) -# Class: (tetrapyrrole binding) - -AnnotationAssertion(Annotation( "GOC:curators") Annotation( "ISBN:0198506732") "Binding to a tetrapyrrole, a compound containing four pyrrole nuclei variously substituted and linked to each other through carbons at the alpha position.") -AnnotationAssertion( "porphyrin binding") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0046906") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "tetrapyrrole binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (intracellular transport) - -AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of substances within a cell.") -AnnotationAssertion( "jl") -AnnotationAssertion( "2013-12-18T14:04:50Z") -AnnotationAssertion( "GO:1902582") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "single organism intracellular transport") -AnnotationAssertion( "single-organism intracellular transport") -AnnotationAssertion( "GO:0046907") -AnnotationAssertion(rdfs:label "intracellular transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (transition metal ion binding) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "Binding to a transition metal ions; a transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0046914") -AnnotationAssertion(rdfs:label "transition metal ion binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (transition metal ion transmembrane transporter activity) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "Enables the transfer of transition metal ions from one side of a membrane to the other. A transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0046915") -AnnotationAssertion(rdfs:label "transition metal ion transmembrane transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (regulation of neurotransmitter secretion) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of the regulated release of a neurotransmitter from a cell.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046928") -AnnotationAssertion(rdfs:label "regulation of neurotransmitter secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (negative regulation of neurotransmitter secretion) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a neurotransmitter.") -AnnotationAssertion( "down regulation of neurotransmitter secretion") -AnnotationAssertion( "down-regulation of neurotransmitter secretion") -AnnotationAssertion( "downregulation of neurotransmitter secretion") -AnnotationAssertion( "conotoxin activity") -AnnotationAssertion( "inhibition of neurotransmitter secretion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0046929") -AnnotationAssertion(rdfs:label "negative regulation of neurotransmitter secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (carboxylic acid transport) AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of carboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carboxylic acids are organic acids containing one or more carboxyl (COOH) groups or anions (COO-).") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0046942") AnnotationAssertion(rdfs:label "carboxylic acid transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (carboxylic acid transmembrane transporter activity) - -AnnotationAssertion(Annotation( "GOC:ai") "Enables the transfer of carboxylic acids from one side of a membrane to the other. Carboxylic acids are organic acids containing one or more carboxyl (COOH) groups or anions (COO-).") -AnnotationAssertion(Annotation(rdfs:label "Exchange of isocitrate and 2-oxoglutarate across the peroxisomal membrane") "Reactome:R-HSA-390347") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0046943") -AnnotationAssertion(rdfs:label "carboxylic acid transmembrane transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (vesicle transport along microtubule) - -AnnotationAssertion(Annotation( "GOC:ecd") Annotation( "GOC:rl") "The directed movement of a vesicle along a microtubule, mediated by motor proteins. This process begins with the attachment of a vesicle to a microtubule, and ends when the vesicle reaches its final destination.") -AnnotationAssertion(Annotation( "GOC:rl") "microtubule-based vesicle localization") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0047496") -AnnotationAssertion(rdfs:label "vesicle transport along microtubule") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (antigen processing and presentation of peptide antigen) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") Annotation( "PMID:15771591") "The process in which an antigen-presenting cell expresses peptide antigen in association with an MHC protein complex on its cell surface, including proteolysis and transport steps for the peptide antigen both prior to and following assembly with the MHC protein complex. The peptide antigen is typically, but not always, processed from an endogenous or exogenous protein.") -AnnotationAssertion( "antigen presentation, peptide antigen") -AnnotationAssertion( "peptide antigen processing and presentation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048002") -AnnotationAssertion(rdfs:label "antigen processing and presentation of peptide antigen") -SubClassOf( ) - -# Class: (CCR chemokine receptor binding) - -AnnotationAssertion(Annotation( "GOC:ai") "Binding to a CCR chemokine receptor.") -AnnotationAssertion( "beta chemokine receptor binding") -AnnotationAssertion( "CCR chemokine receptor ligand") -AnnotationAssertion( "beta chemokine receptor ligand") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0048020") -AnnotationAssertion(rdfs:label "CCR chemokine receptor binding") -SubClassOf( ) - -# Class: (monosaccharide binding) - -AnnotationAssertion(Annotation( "GOC:jid") "Binding to a monosaccharide. Monosaccharides are the simplest carbohydrates; they are polyhydroxy aldehydes H[CH(OH)]nC(=O)H or polyhydroxy ketones H[CHOH]nC(=O)[CHOH]mH with three or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0048029") -AnnotationAssertion(rdfs:label "monosaccharide binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (embryonic eye morphogenesis) - -AnnotationAssertion(Annotation( "GOC:jid") "The process occurring in the embryo by which the anatomical structures of the post-embryonic eye are generated and organized.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048048") -AnnotationAssertion(rdfs:label "embryonic eye morphogenesis") -SubClassOf( ) -SubClassOf( ) - -# Class: (compound eye corneal lens development) - -AnnotationAssertion(Annotation( "GOC:jid") "The process whose specific outcome is the progression of the corneal lens in the compound eye over time, from its formation to the mature structure. The corneal lens is a chitinous extracellular secretion of the four underlying cone cells and the pigment cells.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048058") -AnnotationAssertion(rdfs:label "compound eye corneal lens development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - -# Class: (developmental pigmentation) - -AnnotationAssertion(Annotation( "ISBN:0582227089") "The developmental process that results in the deposition of coloring matter in an organism, tissue or cell.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "pigmentation during development") -AnnotationAssertion( "GO:0048066") -AnnotationAssertion(rdfs:label "developmental pigmentation") -SubClassOf( ) - -# Class: (regulation of developmental pigmentation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GOC:tb") "Any process that modulates the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism.") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "regulation of pigmentation during development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048070") -AnnotationAssertion(rdfs:label "regulation of developmental pigmentation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of developmental pigmentation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GOC:tb") "Any process that decreases the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism.") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "down regulation of developmental pigmentation") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "down-regulation of developmental pigmentation") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "downregulation of developmental pigmentation") -AnnotationAssertion( "inhibition of pigmentation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048086") -AnnotationAssertion(rdfs:label "negative regulation of developmental pigmentation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of developmental pigmentation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GOC:tb") "Any process that increases the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism.") -AnnotationAssertion(Annotation( "GOC:dph") "up regulation of developmental pigmentation") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "up-regulation of developmental pigmentation") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "upregulation of developmental pigmentation") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "activation of developmental pigmentation") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "stimulation of developmental pigmentation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048087") -AnnotationAssertion(rdfs:label "positive regulation of developmental pigmentation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (somatic stem cell division) - -AnnotationAssertion(Annotation( "GOC:jid") Annotation( "ISBN:0582227089") "The self-renewing division of a somatic stem cell, a stem cell that can give rise to cell types of the body other than those of the germ-line.") -AnnotationAssertion( "somatic stem cell renewal") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048103") -AnnotationAssertion(rdfs:label "somatic stem cell division") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (female germ-line stem cell asymmetric division) - -AnnotationAssertion(Annotation( "GOC:jid") Annotation( "GOC:mtg_sensu") "The self-renewing division of a germline stem cell in the female gonad, to produce a daughter stem cell and a daughter germ cell, which will divide to form the female gametes.") -AnnotationAssertion( "GO:0048141") -AnnotationAssertion( "female germ-line stem cell renewal") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048132") -AnnotationAssertion(rdfs:label "female germ-line stem cell asymmetric division") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - -# Class: (spermatocyte division) - -AnnotationAssertion(Annotation( "GOC:jid") Annotation( "GOC:pr") Annotation( "ISBN:0879694238") "The meiotic divisions undergone by the primary and secondary spermatocytes to produce haploid spermatids.") -AnnotationAssertion( "spermatocyte cell division") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048137") -AnnotationAssertion(rdfs:label "spermatocyte division") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (astrocyte activation) - -AnnotationAssertion(Annotation( "GOC:mgi_curators") Annotation( "PMID:10526094") Annotation( "PMID:10695728") Annotation( "PMID:12529254") Annotation( "PMID:12580336") Annotation( "PMID:9585813") "A change in morphology and behavior of an astrocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048143") -AnnotationAssertion(rdfs:label "astrocyte activation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (fibroblast proliferation) - -AnnotationAssertion(Annotation( "GOC:jid") "The multiplication or reproduction of fibroblast cells, resulting in the expansion of the fibroblast population.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048144") -AnnotationAssertion(rdfs:label "fibroblast proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of fibroblast proliferation) - -AnnotationAssertion(Annotation( "GOC:jid") "Any process that modulates the frequency, rate or extent of multiplication or reproduction of fibroblast cells.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048145") -AnnotationAssertion(rdfs:label "regulation of fibroblast proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of fibroblast proliferation) - -AnnotationAssertion(Annotation( "GOC:jid") "Any process that activates or increases the frequency, rate or extent of multiplication or reproduction of fibroblast cells.") -AnnotationAssertion( "up regulation of fibroblast proliferation") -AnnotationAssertion( "up-regulation of fibroblast proliferation") -AnnotationAssertion( "upregulation of fibroblast proliferation") -AnnotationAssertion( "activation of fibroblast proliferation") -AnnotationAssertion( "stimulation of fibroblast proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048146") -AnnotationAssertion(rdfs:label "positive regulation of fibroblast proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of fibroblast proliferation) - -AnnotationAssertion(Annotation( "GOC:jid") "Any process that stops, prevents, or reduces the frequency, rate or extent of multiplication or reproduction of fibroblast cells.") -AnnotationAssertion( "down regulation of fibroblast proliferation") -AnnotationAssertion( "down-regulation of fibroblast proliferation") -AnnotationAssertion( "downregulation of fibroblast proliferation") -AnnotationAssertion( "inhibition of fibroblast proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048147") -AnnotationAssertion(rdfs:label "negative regulation of fibroblast proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (multi-layer follicle stage) - -AnnotationAssertion(Annotation( "GOC:jid") Annotation( "GOC:mtg_sensu") Annotation( "ISBN:0198542771") "The stage in oogenesis when many layers of follicle cells surround the oocyte. There is a yolk nucleus (Balbiani's Body) near the germinal vesicle.") -AnnotationAssertion( "mammalian oogenesis stage 5") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048162") -AnnotationAssertion(rdfs:label "multi-layer follicle stage") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - -# Class: (fused antrum stage) - -AnnotationAssertion(Annotation( "GOC:jid") Annotation( "GOC:mtg_sensu") Annotation( "ISBN:0198542771") "The stage in oogenesis when the antral spaces fuse to form a single antral space. The oocyte is suspended in the cumulus oophorous and the first polar body in the perivitelline space.") -AnnotationAssertion( "mammalian oogenesis stage 8") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048165") -AnnotationAssertion(rdfs:label "fused antrum stage") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - -# Class: (Golgi vesicle transport) - -AnnotationAssertion(Annotation( "GOC:jid") Annotation( "ISBN:0716731363") Annotation( "PMID:10219233") "The directed movement of substances into, out of or within the Golgi apparatus, mediated by vesicles.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "Golgi-derived vesicle transport") -AnnotationAssertion( "GO:0048193") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "Golgi vesicle transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (Golgi vesicle budding) - -AnnotationAssertion(Annotation( "GOC:jid") Annotation( "ISBN:0716731363") Annotation( "PMID:10219233") "The evagination of the Golgi membrane, resulting in formation of a vesicle.") -AnnotationAssertion( "Golgi-derived vesicle budding") -AnnotationAssertion( "dictyosome vesicle budding") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048194") -AnnotationAssertion(rdfs:label "Golgi vesicle budding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (vesicle targeting, to, from or within Golgi) - -AnnotationAssertion(Annotation( "GOC:jid") Annotation( "GOC:mah") Annotation( "ISBN:0716731363") Annotation( "PMID:10219233") "The process in which vesicles are directed to specific destination membranes during transport to, from or within the Golgi apparatus; mediated by the addition of specific coat proteins, including COPI and COPII proteins and clathrin, to the membrane during vesicle formation.") -AnnotationAssertion( "Golgi vesicle targeting") -AnnotationAssertion( "dictyosome vesicle targeting") -AnnotationAssertion( "vesicle targeting, to, from or within dictyosome") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048199") -AnnotationAssertion(rdfs:label "vesicle targeting, to, from or within Golgi") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (regulation of vesicle targeting, to, from or within Golgi) - -AnnotationAssertion(Annotation( "GOC:jid") Annotation( "GOC:mah") Annotation( "ISBN:0716731363") Annotation( "PMID:10219233") "Any process that modulates the frequency, rate, or destination of vesicle-mediated transport to, from or within the Golgi apparatus.") -AnnotationAssertion( "regulation of Golgi vesicle targeting") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048209") -AnnotationAssertion(rdfs:label "regulation of vesicle targeting, to, from or within Golgi") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) # Class: (male gamete generation) @@ -88914,24 +25798,6 @@ SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (epinephrine transport) - -AnnotationAssertion(Annotation( "GOC:jid") "The directed movement of epinephrine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion( "adrenaline transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048241") -AnnotationAssertion(rdfs:label "epinephrine transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (epinephrine secretion) - -AnnotationAssertion(Annotation( "GOC:ef") Annotation( "GOC:jid") "The regulated release of epinephrine by a cell. Epinephrine is a catecholamine hormone secreted by the adrenal medulla and a neurotransmitter, released by certain neurons and active in the central nervous system.") -AnnotationAssertion( "adrenaline secretion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048242") -AnnotationAssertion(rdfs:label "epinephrine secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (norepinephrine secretion) AnnotationAssertion(Annotation( "GOC:ef") Annotation( "GOC:jid") "The regulated release of norepinephrine by a cell. Norepinephrine is a catecholamine and it acts as a hormone and as a neurotransmitter of most of the sympathetic nervous system.") @@ -88939,278 +25805,17 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0048243") AnnotationAssertion(rdfs:label "norepinephrine secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (macrophage chemotaxis) - -AnnotationAssertion(Annotation( "GOC:jid") "The movement of a macrophage in response to an external stimulus.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048246") -AnnotationAssertion(rdfs:label "macrophage chemotaxis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (lymphocyte chemotaxis) - -AnnotationAssertion(Annotation( "GOC:hjd") Annotation( "GOC:jid") Annotation( "PMID:12391252") "The directed movement of a lymphocyte in response to an external stimulus.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048247") -AnnotationAssertion(rdfs:label "lymphocyte chemotaxis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (elastic fiber assembly) - -AnnotationAssertion(Annotation( "GOC:jid") Annotation( "PMID:10841810") Annotation( "PMID:12615674") "Assembly of the extracellular matrix fibers that enables the matrix to recoil after transient stretching.") -AnnotationAssertion( "elastic fibre assembly") -AnnotationAssertion(Annotation( "GOC:BHF") "elastin fiber assembly") -AnnotationAssertion(Annotation( "GOC:BHF") "elastin fibre assembly") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048251") -AnnotationAssertion(rdfs:label "elastic fiber assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (vesicle fusion with Golgi apparatus) - -AnnotationAssertion(Annotation( "GOC:jid") "The joining of the lipid bilayer membrane around a vesicle to the lipid bilayer membrane around the Golgi.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048280") -AnnotationAssertion(rdfs:label "vesicle fusion with Golgi apparatus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (organelle fusion) - -AnnotationAssertion(Annotation( "GOC:jid") "The creation of a single organelle from two or more organelles.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048284") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "organelle fusion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (organelle fission) - -AnnotationAssertion(Annotation( "GOC:jid") "The creation of two or more organelles by division of one organelle.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048285") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "organelle fission") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (lung alveolus development) - -AnnotationAssertion(Annotation( "GOC:mtg_lung") Annotation( "PMID:9751757") "The process whose specific outcome is the progression of the alveolus over time, from its formation to the mature structure. The alveolus is a sac for holding air in the lungs; formed by the terminal dilation of air passageways.") -AnnotationAssertion(Annotation( "PMID:17911382") "alveolarization") -AnnotationAssertion(Annotation( "GOC:17911382") "alveologenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048286") -AnnotationAssertion(rdfs:label "lung alveolus development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (nuclear membrane fusion involved in karyogamy) - -AnnotationAssertion(Annotation( "GOC:jid") "The joining of 2 or more lipid bilayer membranes that surround the nucleus during the creation of a single nucleus from multiple nuclei.") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "nuclear membrane fusion during karyogamy") -AnnotationAssertion( "GO:0048288") -AnnotationAssertion(rdfs:label "nuclear membrane fusion involved in karyogamy") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (calcium-dependent protein binding) - -AnnotationAssertion(Annotation( "GOC:jid") Annotation( "PMID:10485905") "Binding to a protein or protein complex in the presence of calcium.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0048306") -AnnotationAssertion(rdfs:label "calcium-dependent protein binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (organelle inheritance) - -AnnotationAssertion(Annotation( "GOC:jid") "The partitioning of organelles between daughter cells at cell division.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048308") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "organelle inheritance") -SubClassOf( ) - -# Class: (Golgi inheritance) - -AnnotationAssertion(Annotation( "GOC:jid") Annotation( "PMID:12851069") "The partitioning of Golgi apparatus between daughter cells at cell division.") -AnnotationAssertion( "Golgi apparatus inheritance") -AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "Golgi division") -AnnotationAssertion( "Golgi partitioning") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048313") -AnnotationAssertion(rdfs:label "Golgi inheritance") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (axial mesoderm development) - -AnnotationAssertion(Annotation( "GOC:dgh") "The process whose specific outcome is the progression of the axial mesoderm over time, from its formation to the mature structure. The axial mesoderm includes the prechordal mesoderm and the chordamesoderm. It gives rise to the prechordal plate and to the notochord.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048318") -AnnotationAssertion(rdfs:label "axial mesoderm development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (axial mesoderm morphogenesis) - -AnnotationAssertion(Annotation( "GOC:go_curators") "The process in which the anatomical structures of the axial mesoderm are generated and organized.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048319") -AnnotationAssertion(rdfs:label "axial mesoderm morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (axial mesoderm formation) - -AnnotationAssertion(Annotation( "GOC:dgh") "The process that gives rise to the axial mesoderm. This process pertains to the initial formation of the structure from unspecified parts.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048320") -AnnotationAssertion(rdfs:label "axial mesoderm formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (mesoderm morphogenesis) AnnotationAssertion(Annotation( "GOC:go_curators") "The process in which the anatomical structures of the mesoderm are generated and organized.") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0048332") AnnotationAssertion(rdfs:label "mesoderm morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (mesodermal cell differentiation) - -AnnotationAssertion(Annotation( "GOC:dgh") "The process in which a relatively unspecialized cell acquires the specialized features of a mesoderm cell.") -AnnotationAssertion( "mesoderm cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048333") -AnnotationAssertion(rdfs:label "mesodermal cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (paraxial mesoderm development) - -AnnotationAssertion(Annotation( "GOC:dgh") "The process whose specific outcome is the progression of the paraxial mesoderm over time, from its formation to the mature structure. The paraxial mesoderm is the mesoderm located bilaterally adjacent to the notochord and neural tube.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048339") -AnnotationAssertion(rdfs:label "paraxial mesoderm development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (paraxial mesoderm morphogenesis) - -AnnotationAssertion(Annotation( "GOC:go_curators") "The process in which the anatomical structures of the paraxial mesoderm are generated and organized.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048340") -AnnotationAssertion(rdfs:label "paraxial mesoderm morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (paraxial mesoderm formation) - -AnnotationAssertion(Annotation( "GOC:dgh") "The process that gives rise to the paraxial mesoderm. This process pertains to the initial formation of the structure from unspecified parts.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048341") -AnnotationAssertion(rdfs:label "paraxial mesoderm formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (lateral mesoderm development) - -AnnotationAssertion(Annotation( "GOC:go_curators") "The process whose specific outcome is the progression of the lateral mesoderm over time, from its formation to the mature structure.") -AnnotationAssertion( "lateral plate mesoderm development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048368") -AnnotationAssertion(rdfs:label "lateral mesoderm development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (lateral mesoderm morphogenesis) - -AnnotationAssertion(Annotation( "GOC:go_curators") "The process in which the anatomical structures of the lateral mesoderm are generated and organized.") -AnnotationAssertion( "lateral plate mesoderm morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048369") -AnnotationAssertion(rdfs:label "lateral mesoderm morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (lateral mesoderm formation) - -AnnotationAssertion(Annotation( "GOC:jid") "The process that gives rise to the lateral mesoderm. This process pertains to the initial formation of the structure from unspecified parts.") -AnnotationAssertion( "lateral plate mesoderm biosynthesis") -AnnotationAssertion( "lateral plate mesoderm formation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048370") -AnnotationAssertion(rdfs:label "lateral mesoderm formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (mesectoderm development) - -AnnotationAssertion(Annotation( "GOC:jid") "The process whose specific outcome is the progression of the mesectoderm over time, from its formation to the mature structure. In animal embryos, mesectoderm development processes give rise to both mesoderm and ectoderm tissues.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048383") -AnnotationAssertion(rdfs:label "mesectoderm development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (intermediate mesoderm development) - -AnnotationAssertion(Annotation( "GOC:dgh") "The process whose specific outcome is the progression of the intermediate mesoderm over time, from its formation to the mature structure. The intermediate mesoderm is located between the lateral mesoderm and the paraxial mesoderm. It develops into the kidney and gonads.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048389") -AnnotationAssertion(rdfs:label "intermediate mesoderm development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (intermediate mesoderm morphogenesis) - -AnnotationAssertion(Annotation( "GOC:go_curators") "The process in which the anatomical structures of the intermediate mesoderm are generated and organized.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048390") -AnnotationAssertion(rdfs:label "intermediate mesoderm morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (intermediate mesoderm formation) - -AnnotationAssertion(Annotation( "GOC:dgh") "The process that gives rise to the intermediate mesoderm. This process pertains to the initial formation of the structure from unspecified parts.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048391") -AnnotationAssertion(rdfs:label "intermediate mesoderm formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (cell development) AnnotationAssertion(Annotation( "GOC:go_curators") "The cellular developmental process in which a specific cell progresses from an immature to a mature state. Cell development start once cell commitment has taken place.") @@ -89220,7 +25825,6 @@ AnnotationAssertion(Annotation( "GO:0048468") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "cell development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) @@ -89234,7 +25838,6 @@ AnnotationAssertion(Annotation( "GO:0048469") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "cell maturation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) @@ -89249,63 +25852,12 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:0048477") AnnotationAssertion(rdfs:label "oogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectAllValuesFrom( )) -# Class: (autonomic nervous system development) - -AnnotationAssertion(Annotation( "FMA:9905") Annotation( "GOC:jid") Annotation( "GOC:sr") "The process whose specific outcome is the progression of the autonomic nervous system over time, from its formation to the mature structure. The autonomic nervous system is composed of neurons that are not under conscious control, and is comprised of two antagonistic components, the sympathetic and parasympathetic nervous systems. The autonomic nervous system regulates key functions including the activity of the cardiac (heart) muscle, smooth muscles (e.g. of the gut), and glands.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048483") -AnnotationAssertion(rdfs:label "autonomic nervous system development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (enteric nervous system development) - -AnnotationAssertion(Annotation( "FMA:66070") Annotation( "GOC:jid") Annotation( "GOC:sr") "The process whose specific outcome is the progression of the enteric nervous system over time, from its formation to the mature structure. The enteric nervous system is composed of two ganglionated neural plexuses in the gut wall which form one of the three major divisions of the autonomic nervous system. The enteric nervous system innervates the gastrointestinal tract, the pancreas, and the gallbladder. It contains sensory neurons, interneurons, and motor neurons. Thus the circuitry can autonomously sense the tension and the chemical environment in the gut and regulate blood vessel tone, motility, secretions, and fluid transport. The system is itself governed by the central nervous system and receives both parasympathetic and sympathetic innervation.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048484") -AnnotationAssertion(rdfs:label "enteric nervous system development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (sympathetic nervous system development) - -AnnotationAssertion(Annotation( "FMA:9906") Annotation( "GOC:jid") Annotation( "GOC:sr") "The process whose specific outcome is the progression of the sympathetic nervous system over time, from its formation to the mature structure. The sympathetic nervous system is one of the two divisions of the vertebrate autonomic nervous system (the other being the parasympathetic nervous system). The sympathetic preganglionic neurons have their cell bodies in the thoracic and lumbar regions of the spinal cord and connect to the paravertebral chain of sympathetic ganglia. Innervate heart and blood vessels, sweat glands, viscera and the adrenal medulla. Most sympathetic neurons, but not all, use noradrenaline as a post-ganglionic neurotransmitter.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048485") -AnnotationAssertion(rdfs:label "sympathetic nervous system development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (parasympathetic nervous system development) - -AnnotationAssertion(Annotation( "FMA:9907") Annotation( "GOC:jid") Annotation( "GOC:sr") "The process whose specific outcome is the progression of the parasympathetic nervous system over time, from its formation to the mature structure. The parasympathetic nervous system is one of the two divisions of the vertebrate autonomic nervous system. Parasympathetic nerves emerge cranially as pre ganglionic fibers from oculomotor, facial, glossopharyngeal and vagus and from the sacral region of the spinal cord. Most neurons are cholinergic and responses are mediated by muscarinic receptors. The parasympathetic system innervates, for example: salivary glands, thoracic and abdominal viscera, bladder and genitalia.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048486") -AnnotationAssertion(rdfs:label "parasympathetic nervous system development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (regulation of timing of cell differentiation) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GOC:tb") "The process controlling the activation and/or rate at which relatively unspecialized cells acquire specialized features. Any process that modulates the rate, frequency or extent of the XXX at a consistent predetermined time point during its development.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "timing of cell differentiation") -AnnotationAssertion( "GO:0048505") -AnnotationAssertion(rdfs:label "regulation of timing of cell differentiation") -SubClassOf( ) -SubClassOf( ) - # Class: (rhythmic process) AnnotationAssertion(Annotation( "GOC:jid") "Any process pertinent to the generation and maintenance of rhythms in the physiology of an organism.") @@ -89318,41 +25870,18 @@ SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectAllValuesFrom( )) -# Class: (circadian behavior) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:go_curators") Annotation( "GOC:pr") "The specific behavior of an organism that recurs with a regularity of approximately 24 hours.") -AnnotationAssertion( "circadian rhythm behavior") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048512") -AnnotationAssertion(rdfs:label "circadian behavior") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - # Class: (animal organ development) AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:jid") "Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/25943"^^xsd:anyURI) AnnotationAssertion( "Wikipedia:Organogenesis") AnnotationAssertion( "development of an organ") AnnotationAssertion( "organogenesis") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0048513") AnnotationAssertion(rdfs:label "animal organ development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (blood vessel morphogenesis) - -AnnotationAssertion(Annotation( "GOC:jid") "The process in which the anatomical structures of blood vessels are generated and organized. The blood vessel is the vasculature carrying blood.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048514") -AnnotationAssertion(rdfs:label "blood vessel morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (spermatid differentiation) AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:jid") "The process whose specific outcome is the progression of a spermatid over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.") @@ -89360,7 +25889,6 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0048515") AnnotationAssertion(rdfs:label "spermatid differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ) @@ -89380,7 +25908,6 @@ AnnotationAssertion( "GO:0048518") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "positive regulation of biological process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) # Class: (negative regulation of biological process) @@ -89396,295 +25923,8 @@ AnnotationAssertion( "GO:0048519") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "negative regulation of biological process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (positive regulation of behavior) - -AnnotationAssertion(Annotation( "GOC:jid") Annotation( "GOC:pr") "Any process that activates or increases the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli.") -AnnotationAssertion( "up regulation of behavior") -AnnotationAssertion( "up-regulation of behavior") -AnnotationAssertion( "upregulation of behavior") -AnnotationAssertion( "activation of behavior") -AnnotationAssertion( "stimulation of behavior") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048520") -AnnotationAssertion(rdfs:label "positive regulation of behavior") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of behavior) - -AnnotationAssertion(Annotation( "GOC:jid") Annotation( "GOC:pr") "Any process that stops, prevents, or reduces the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli.") -AnnotationAssertion( "down regulation of behavior") -AnnotationAssertion( "down-regulation of behavior") -AnnotationAssertion( "downregulation of behavior") -AnnotationAssertion( "inhibition of behavior") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048521") -AnnotationAssertion(rdfs:label "negative regulation of behavior") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of cellular process) - -AnnotationAssertion(Annotation( "GOC:jid") "Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.") -AnnotationAssertion( "GO:0051242") -AnnotationAssertion( "positive regulation of cellular physiological process") -AnnotationAssertion( "up regulation of cellular process") -AnnotationAssertion( "up-regulation of cellular process") -AnnotationAssertion( "upregulation of cellular process") -AnnotationAssertion( "activation of cellular process") -AnnotationAssertion( "stimulation of cellular process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048522") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "positive regulation of cellular process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of cellular process) - -AnnotationAssertion(Annotation( "GOC:jid") "Any process that stops, prevents, or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.") -AnnotationAssertion( "GO:0051243") -AnnotationAssertion( "down regulation of cellular process") -AnnotationAssertion( "down-regulation of cellular process") -AnnotationAssertion( "downregulation of cellular process") -AnnotationAssertion( "negative regulation of cellular physiological process") -AnnotationAssertion( "inhibition of cellular process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048523") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "negative regulation of cellular process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (hematopoietic or lymphoid organ development) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:rl") Annotation( "ISBN:0781735149") "The process whose specific outcome is the progression of any organ involved in hematopoiesis (also known as hemopoiesis) or lymphoid cell activation over time, from its formation to the mature structure. Such development includes differentiation of resident cell types (stromal cells) and of migratory cell types dependent on the unique microenvironment afforded by the organ for their proper differentiation.") -AnnotationAssertion( "haematopoietic or lymphoid organ development") -AnnotationAssertion( "haemopoietic or lymphoid organ development") -AnnotationAssertion( "hemopoietic or lymphoid organ development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048534") -AnnotationAssertion(rdfs:label "hematopoietic or lymphoid organ development") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (lymph node development) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:068340007X") Annotation( "ISBN:0781735149") "The process whose specific outcome is the progression of lymph nodes over time, from their formation to the mature structure. A lymph node is a round, oval, or bean shaped structure localized in clusters along the lymphatic vessels, with a distinct internal structure including specialized vasculature and B- and T-zones for the activation of lymphocytes.") -AnnotationAssertion( "lymph gland development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048535") -AnnotationAssertion(rdfs:label "lymph node development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (spleen development) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") "The process whose specific outcome is the progression of the spleen over time, from its formation to the mature structure. The spleen is a large vascular lymphatic organ composed of white and red pulp, involved both in hemopoietic and immune system functions.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048536") -AnnotationAssertion(rdfs:label "spleen development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (mucosa-associated lymphoid tissue development) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") "The process whose specific outcome is the progression of mucosal-associated lymphoid tissue over time, from its formation to the mature structure. Mucosal-associated lymphoid tissue is typically found as nodules associated with mucosal epithelia with distinct internal structures including B- and T-zones for the activation of lymphocytes.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/19918"^^xsd:anyURI) -AnnotationAssertion( "mucosal-associated lymphoid tissue development") -AnnotationAssertion( "BALT development") -AnnotationAssertion( "GALT development") -AnnotationAssertion( "NALT development") -AnnotationAssertion( "bronchial-associated lymphoid tissue development") -AnnotationAssertion( "gut-associated lymphoid tissue development") -AnnotationAssertion( "nasopharyngeal-associated lymphoid tissue development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048537") -AnnotationAssertion(rdfs:label "mucosa-associated lymphoid tissue development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (thymus development) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") "The process whose specific outcome is the progression of the thymus over time, from its formation to the mature structure. The thymus is a symmetric bi-lobed organ involved primarily in the differentiation of immature to mature T cells, with unique vascular, nervous, epithelial, and lymphoid cell components.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048538") -AnnotationAssertion(rdfs:comment "Note that this term is reserved for annotation of gene products involved in the formation of the thymus itself, not for gene products involved in T cell differentiation in the thymus or elsewhere.") -AnnotationAssertion(rdfs:label "thymus development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (bone marrow development) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") "The process whose specific outcome is the progression of the bone marrow over time, from its formation to the mature structure.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048539") -AnnotationAssertion(rdfs:label "bone marrow development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (bursa of Fabricius development) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") "The process whose specific outcome is the progression of the bursa of Fabricius over time, from its formation to the mature structure. The bursa of Fabricius is an organ found in birds involved in B cell differentiation.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048540") -AnnotationAssertion(rdfs:label "bursa of Fabricius development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - -# Class: (Peyer's patch development) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") "The process whose specific outcome is the progression of Peyer's patches over time, from their formation to the mature structure. Peyer's patches are typically found as nodules associated with gut epithelium with distinct internal structures including B- and T-zones for the activation of lymphocytes.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GALT development") -AnnotationAssertion( "gut-associated lymphoid tissue development") -AnnotationAssertion( "GO:0048541") -AnnotationAssertion(rdfs:label "Peyer's patch development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (response to steroid hormone) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a steroid hormone stimulus.") -AnnotationAssertion(Annotation( "GOC:dos") "response to steroid hormone stimulus") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048545") -AnnotationAssertion(rdfs:label "response to steroid hormone") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (digestive tract morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:go_curators") Annotation( "PMID:12618131") "The process in which the anatomical structures of the digestive tract are generated and organized. The digestive tract is the anatomical structure through which food passes and is processed.") -AnnotationAssertion( "GO:0048547") -AnnotationAssertion(Annotation( "GOC:dph") "gut morphogenesis") -AnnotationAssertion( "alimentary canal morphogenesis") -AnnotationAssertion( "digestive tube morphogenesis") -AnnotationAssertion( "gastrointestinal tract morphogenesis") -AnnotationAssertion( "intestinal morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048546") -AnnotationAssertion(rdfs:label "digestive tract morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (embryonic organ morphogenesis) - -AnnotationAssertion(Annotation( "GOC:jid") "Morphogenesis, during the embryonic phase, of a tissue or tissues that work together to perform a specific function or functions. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048562") -AnnotationAssertion(rdfs:label "embryonic organ morphogenesis") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (post-embryonic animal organ morphogenesis) - -AnnotationAssertion(Annotation( "GOC:jid") "Morphogenesis, during the post-embryonic phase, of an animal tissue or tissues that work together to perform a specific function or functions. Morphogenesis pertains to process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048563") -AnnotationAssertion(rdfs:label "post-embryonic animal organ morphogenesis") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (digestive tract development) - -AnnotationAssertion(Annotation( "GOC:go_curators") "The process whose specific outcome is the progression of the digestive tract over time, from its formation to the mature structure. The digestive tract is the anatomical structure through which food passes and is processed.") -AnnotationAssertion(Annotation( "GOC:dph") "gut development") -AnnotationAssertion( "intestinal development") -AnnotationAssertion( "intestine development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048565") -AnnotationAssertion(rdfs:label "digestive tract development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (embryonic organ development) - -AnnotationAssertion(Annotation( "GOC:jid") "Development, taking place during the embryonic phase, of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.") -AnnotationAssertion( "embryonic organogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048568") -AnnotationAssertion(rdfs:label "embryonic organ development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (post-embryonic animal organ development) - -AnnotationAssertion(Annotation( "GOC:jid") "Development, taking place during the post-embryonic phase of an animal tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.") -AnnotationAssertion( "post-embryonic animal organogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048569") -AnnotationAssertion(rdfs:label "post-embryonic animal organ development") -SubClassOf( ) -SubClassOf( ) - -# Class: (notochord morphogenesis) - -AnnotationAssertion(Annotation( "GOC:jid") "The process in which the anatomical structures of the notochord are generated and organized. The notochord is a mesoderm-derived structure located ventral of the developing nerve cord. In vertebrates, the notochord serves as a core around which other mesodermal cells form the vertebrae. In the most primitive chordates, which lack vertebrae, the notochord persists as a substitute for a vertebral column.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048570") -AnnotationAssertion(rdfs:label "notochord morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (regulation of post-embryonic development) - -AnnotationAssertion(Annotation( "GOC:jid") "Any process that modulates the frequency, rate or extent of post-embryonic development. Post-embryonic development is defined as the process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048580") -AnnotationAssertion(rdfs:label "regulation of post-embryonic development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (negative regulation of post-embryonic development) - -AnnotationAssertion(Annotation( "GOC:jid") "Any process that stops, prevents, or reduces the frequency, rate or extent of post-embryonic development. Post-embryonic development is defined as the process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure.") -AnnotationAssertion( "down regulation of post-embryonic development") -AnnotationAssertion( "down-regulation of post-embryonic development") -AnnotationAssertion( "downregulation of post-embryonic development") -AnnotationAssertion( "inhibition of post-embryonic development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048581") -AnnotationAssertion(rdfs:label "negative regulation of post-embryonic development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of post-embryonic development) - -AnnotationAssertion(Annotation( "GOC:jid") "Any process that activates or increases the frequency, rate or extent of post-embryonic development. Post-embryonic development is defined as the process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure.") -AnnotationAssertion( "up regulation of post-embryonic development") -AnnotationAssertion( "up-regulation of post-embryonic development") -AnnotationAssertion( "upregulation of post-embryonic development") -AnnotationAssertion( "activation of post-embryonic development") -AnnotationAssertion( "stimulation of post-embryonic development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048582") -AnnotationAssertion(rdfs:label "positive regulation of post-embryonic development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - # Class: (regulation of response to stimulus) AnnotationAssertion(Annotation( "GOC:jid") "Any process that modulates the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.") @@ -89693,42 +25933,8 @@ AnnotationAssertion( ) AnnotationAssertion(rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.") AnnotationAssertion(rdfs:label "regulation of response to stimulus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (positive regulation of response to stimulus) - -AnnotationAssertion(Annotation( "GOC:jid") "Any process that activates, maintains or increases the rate of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.") -AnnotationAssertion( "up regulation of response to stimulus") -AnnotationAssertion( "up-regulation of response to stimulus") -AnnotationAssertion( "upregulation of response to stimulus") -AnnotationAssertion( "activation of response to stimulus") -AnnotationAssertion( "stimulation of response to stimulus") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048584") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.") -AnnotationAssertion(rdfs:label "positive regulation of response to stimulus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of response to stimulus) - -AnnotationAssertion(Annotation( "GOC:jid") "Any process that stops, prevents, or reduces the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.") -AnnotationAssertion( "down regulation of response to stimulus") -AnnotationAssertion( "down-regulation of response to stimulus") -AnnotationAssertion( "downregulation of response to stimulus") -AnnotationAssertion( "inhibition of response to stimulus") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048585") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.") -AnnotationAssertion(rdfs:label "negative regulation of response to stimulus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - # Class: (developmental cell growth) AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "GOC:isa_complete") "The growth of a cell, where growth contributes to the progression of the cell over time from one condition to another.") @@ -89746,42 +25952,6 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:0048589") AnnotationAssertion(rdfs:label "developmental growth") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (eye morphogenesis) - -AnnotationAssertion(Annotation( "GOC:jid") Annotation( "GOC:mtg_sensu") "The process in which the anatomical structures of the eye are generated and organized.") -AnnotationAssertion( "GO:0048748") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048592") -AnnotationAssertion(rdfs:label "eye morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (camera-type eye morphogenesis) - -AnnotationAssertion(Annotation( "GOC:jid") Annotation( "GOC:mtg_sensu") "The process in which the anatomical structures of the eye are generated and organized. The camera-type eye is an organ of sight that receives light through an aperture and focuses it through a lens, projecting it on a photoreceptor field.") -AnnotationAssertion( "GO:0048594") -AnnotationAssertion( "GO:0048595") -AnnotationAssertion(Annotation( "GOC:dph") "camera-style eye morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048593") -AnnotationAssertion(rdfs:label "camera-type eye morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (embryonic camera-type eye morphogenesis) - -AnnotationAssertion(Annotation( "GOC:jid") Annotation( "GOC:mtg_sensu") "The process in which the anatomical structures of the eye are generated and organized during embryonic development.") -AnnotationAssertion( "embryonic eye morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048596") -AnnotationAssertion(rdfs:label "embryonic camera-type eye morphogenesis") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) # Class: (embryonic morphogenesis) @@ -89795,30 +25965,6 @@ SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (oocyte development) - -AnnotationAssertion(Annotation( "GOC:go_curators") "The process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048599") -AnnotationAssertion(rdfs:label "oocyte development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (oocyte morphogenesis) - -AnnotationAssertion(Annotation( "GOC:go_curators") "The process in which the structures of an oocyte are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of an oocyte.") -AnnotationAssertion( "oocyte morphogenesis during differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048601") -AnnotationAssertion(rdfs:label "oocyte morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - # Class: (reproductive structure development) AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:isa_complete") Annotation( "GOC:jid") "The reproductive developmental process whose specific outcome is the progression of somatic structures that will be used in the process of creating new individuals from one or more parents, from their formation to the mature structures.") @@ -89841,211 +25987,6 @@ AnnotationAssertion(rdfs:label "mult SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (embryonic hindgut morphogenesis) - -AnnotationAssertion(Annotation( "GOC:jid") Annotation( "GOC:rc") "The process in which the anatomical structures of the hindgut are generated and organized, during the embryonic phase.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048619") -AnnotationAssertion(rdfs:label "embryonic hindgut morphogenesis") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (myoblast development) - -AnnotationAssertion(Annotation( "CL:0000056") Annotation( "GOC:dph") Annotation( "GOC:mtg_muscle") "The process whose specific outcome is the progression of the myoblast over time, from its formation to the mature structure. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048627") -AnnotationAssertion(rdfs:label "myoblast development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (myoblast maturation) - -AnnotationAssertion(Annotation( "CL:0000056") Annotation( "GOC:dph") Annotation( "GOC:mtg_muscle") "A developmental process, independent of morphogenetic (shape) change, that is required for a myoblast to attain its fully functional state. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048628") -AnnotationAssertion(rdfs:label "myoblast maturation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (skeletal muscle tissue growth) - -AnnotationAssertion(Annotation( "GOC:lm") Annotation( "PMID:15726494") Annotation( "PMID:15907921") "The increase in size or mass of a skeletal muscle. This may be due to a change in the fiber number or size.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048630") -AnnotationAssertion(rdfs:label "skeletal muscle tissue growth") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (regulation of skeletal muscle tissue growth) - -AnnotationAssertion(Annotation( "GOC:lm") Annotation( "PMID:15726494") Annotation( "PMID:15907921") "Any process that modulates the frequency, rate or extent of skeletal muscle growth.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048631") -AnnotationAssertion(rdfs:label "regulation of skeletal muscle tissue growth") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of skeletal muscle tissue growth) - -AnnotationAssertion(Annotation( "GOC:lm") Annotation( "PMID:15726494") Annotation( "PMID:15907921") "Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle growth.") -AnnotationAssertion( "down regulation of skeletal muscle growth") -AnnotationAssertion( "down-regulation of skeletal muscle growth") -AnnotationAssertion( "downregulation of skeletal muscle growth") -AnnotationAssertion( "inhibition of skeletal muscle growth") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048632") -AnnotationAssertion(rdfs:label "negative regulation of skeletal muscle tissue growth") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of skeletal muscle tissue growth) - -AnnotationAssertion(Annotation( "GOC:lm") Annotation( "PMID:15726494") Annotation( "PMID:15907921") "Any process that activates, maintains or increases the rate of skeletal muscle growth.") -AnnotationAssertion( "up regulation of skeletal muscle growth") -AnnotationAssertion( "up-regulation of skeletal muscle growth") -AnnotationAssertion( "upregulation of skeletal muscle growth") -AnnotationAssertion( "activation of skeletal muscle growth") -AnnotationAssertion( "stimulation of skeletal muscle growth") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048633") -AnnotationAssertion(rdfs:label "positive regulation of skeletal muscle tissue growth") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (regulation of muscle organ development) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of muscle development.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048634") -AnnotationAssertion(rdfs:label "regulation of muscle organ development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of muscle organ development) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of muscle development.") -AnnotationAssertion( "down regulation of muscle development") -AnnotationAssertion( "down-regulation of muscle development") -AnnotationAssertion( "downregulation of muscle development") -AnnotationAssertion( "inhibition of muscle development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048635") -AnnotationAssertion(rdfs:label "negative regulation of muscle organ development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of muscle organ development) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates, maintains or increases the rate of muscle development.") -AnnotationAssertion( "up regulation of muscle development") -AnnotationAssertion( "up-regulation of muscle development") -AnnotationAssertion( "upregulation of muscle development") -AnnotationAssertion( "activation of muscle development") -AnnotationAssertion( "stimulation of muscle development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048636") -AnnotationAssertion(rdfs:label "positive regulation of muscle organ development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (regulation of developmental growth) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of developmental growth.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048638") -AnnotationAssertion(rdfs:label "regulation of developmental growth") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of developmental growth) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates, maintains or increases the rate of developmental growth.") -AnnotationAssertion( "up regulation of developmental growth") -AnnotationAssertion( "up-regulation of developmental growth") -AnnotationAssertion( "upregulation of developmental growth") -AnnotationAssertion( "activation of developmental growth") -AnnotationAssertion( "stimulation of developmental growth") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048639") -AnnotationAssertion(rdfs:label "positive regulation of developmental growth") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of developmental growth) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of developmental growth.") -AnnotationAssertion( "down regulation of developmental growth") -AnnotationAssertion( "down-regulation of developmental growth") -AnnotationAssertion( "downregulation of developmental growth") -AnnotationAssertion( "inhibition of developmental growth") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048640") -AnnotationAssertion(rdfs:label "negative regulation of developmental growth") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of skeletal muscle tissue development) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of skeletal muscle tissue development.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048641") -AnnotationAssertion(rdfs:label "regulation of skeletal muscle tissue development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of skeletal muscle tissue development) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle tissue development.") -AnnotationAssertion( "down regulation of skeletal muscle development") -AnnotationAssertion( "down-regulation of skeletal muscle development") -AnnotationAssertion( "downregulation of skeletal muscle development") -AnnotationAssertion( "inhibition of skeletal muscle development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048642") -AnnotationAssertion(rdfs:label "negative regulation of skeletal muscle tissue development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of skeletal muscle tissue development) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates, maintains or increases the rate of skeletal muscle tissue development.") -AnnotationAssertion( "up regulation of skeletal muscle development") -AnnotationAssertion( "up-regulation of skeletal muscle development") -AnnotationAssertion( "upregulation of skeletal muscle development") -AnnotationAssertion( "activation of skeletal muscle development") -AnnotationAssertion( "stimulation of skeletal muscle development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048643") -AnnotationAssertion(rdfs:label "positive regulation of skeletal muscle tissue development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (muscle organ morphogenesis) - -AnnotationAssertion(Annotation( "GOC:jid") "The process in which the anatomical structures of muscle are generated and organized.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048644") -AnnotationAssertion(rdfs:label "muscle organ morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (animal organ formation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:jid") "The process pertaining to the initial formation of an animal organ from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure, such as inductive events, and ends when the structural rudiment of the organ is recognizable, such as a condensation of mesenchymal cells into the organ rudiment. Organs are a natural part or structure in an animal or a plant, capable of performing some special action (termed its function), which is essential to the life or well-being of the whole. The heart and lungs are organs of animals, and the petal and leaf are organs of plants. In animals the organs are generally made up of several tissues, one of which usually predominates, and determines the principal function of the organ.") -AnnotationAssertion( "animal organ primordium initiation") -AnnotationAssertion( "initiation of an animal organ primordium") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048645") -AnnotationAssertion(rdfs:label "animal organ formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (anatomical structure formation involved in morphogenesis) AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GOC:tb") "The developmental process pertaining to the initial formation of an anatomical structure from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.") @@ -90058,208 +25999,16 @@ AnnotationAssertion(rdfs:label "anat SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (smooth muscle cell proliferation) - -AnnotationAssertion(Annotation( "CL:0000192") Annotation( "GOC:ebc") Annotation( "PMID:1840698") "The multiplication or reproduction of smooth muscle cells, resulting in the expansion of a cell population.") -AnnotationAssertion( "SMC proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048659") -AnnotationAssertion(rdfs:label "smooth muscle cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of smooth muscle cell proliferation) - -AnnotationAssertion(Annotation( "CL:0000192") Annotation( "GOC:ebc") "Any process that modulates the frequency, rate or extent of smooth muscle cell proliferation.") -AnnotationAssertion( "regulation of SMC proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048660") -AnnotationAssertion(rdfs:label "regulation of smooth muscle cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of smooth muscle cell proliferation) - -AnnotationAssertion(Annotation( "CL:0000192") Annotation( "GOC:ebc") "Any process that activates or increases the rate or extent of smooth muscle cell proliferation.") -AnnotationAssertion( "positive regulation of SMC proliferation") -AnnotationAssertion( "up regulation of smooth muscle cell proliferation") -AnnotationAssertion( "up-regulation of smooth muscle cell proliferation") -AnnotationAssertion( "upregulation of smooth muscle cell proliferation") -AnnotationAssertion( "activation of smooth muscle cell proliferation") -AnnotationAssertion( "stimulation of smooth muscle cell proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048661") -AnnotationAssertion(rdfs:label "positive regulation of smooth muscle cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of smooth muscle cell proliferation) - -AnnotationAssertion(Annotation( "CL:0000192") Annotation( "GOC:ebc") "Any process that stops, prevents or reduces the rate or extent of smooth muscle cell proliferation.") -AnnotationAssertion( "down regulation of smooth muscle cell proliferation") -AnnotationAssertion( "down-regulation of smooth muscle cell proliferation") -AnnotationAssertion( "downregulation of smooth muscle cell proliferation") -AnnotationAssertion( "negative regulation of SMC proliferation") -AnnotationAssertion( "inhibition of smooth muscle cell proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048662") -AnnotationAssertion(rdfs:label "negative regulation of smooth muscle cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (neuron development) - -AnnotationAssertion(Annotation( "GOC:dph") "The process whose specific outcome is the progression of a neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048666") -AnnotationAssertion(rdfs:label "neuron development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cell morphogenesis involved in neuron differentiation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "The process in which the structures of a neuron are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a neuron.") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "neuron morphogenesis involved in differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048667") -AnnotationAssertion(rdfs:label "cell morphogenesis involved in neuron differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (generation of neurons) - -AnnotationAssertion(Annotation( "GOC:nln") "The process in which nerve cells are generated. This includes the production of neuroblasts and their differentiation into neurons.") -AnnotationAssertion( "neuron generation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048699") -AnnotationAssertion(rdfs:label "generation of neurons") -SubClassOf( ) - -# Class: (skeletal system morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:dsf") Annotation( "GOC:jid") Annotation( "GOC:tb") "The process in which the anatomical structures of the skeleton are generated and organized.") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "skeletal morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048705") -AnnotationAssertion(rdfs:label "skeletal system morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (instar larval or pupal morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_sensu") Annotation( "GOC:rc") "The process, occurring during instar larval or pupal development, by which anatomical structures are generated and organized.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048707") -AnnotationAssertion(rdfs:label "instar larval or pupal morphogenesis") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (astrocyte differentiation) - -AnnotationAssertion(Annotation( "GOC:vp") Annotation( "PMID:15139015") "The process in which a relatively unspecialized cell acquires the specialized features of an astrocyte. An astrocyte is the most abundant type of glial cell. Astrocytes provide support for neurons and regulate the environment in which they function.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048708") -AnnotationAssertion(rdfs:label "astrocyte differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (oligodendrocyte differentiation) - -AnnotationAssertion(Annotation( "GOC:vp") Annotation( "PMID:15139015") "The process in which a relatively unspecialized cell acquires the specialized features of an oligodendrocyte. An oligodendrocyte is a type of glial cell involved in myelinating the axons of neurons in the central nervous system.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048709") -AnnotationAssertion(rdfs:label "oligodendrocyte differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (regulation of astrocyte differentiation) - -AnnotationAssertion(Annotation( "GOC:vp") Annotation( "PMID:15139015") "Any process that modulates the frequency, rate or extent of astrocyte differentiation.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048710") -AnnotationAssertion(rdfs:label "regulation of astrocyte differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of astrocyte differentiation) - -AnnotationAssertion(Annotation( "GOC:vp") Annotation( "PMID:15139015") "Any process that activates or increases the frequency, rate or extent of astrocyte differentiation.") -AnnotationAssertion( "up regulation of astrocyte differentiation") -AnnotationAssertion( "up-regulation of astrocyte differentiation") -AnnotationAssertion( "upregulation of astrocyte differentiation") -AnnotationAssertion( "activation of astrocyte differentiation") -AnnotationAssertion( "stimulation of astrocyte differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048711") -AnnotationAssertion(rdfs:label "positive regulation of astrocyte differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of astrocyte differentiation) - -AnnotationAssertion(Annotation( "GOC:vp") Annotation( "PMID:15139015") "Any process that stops, prevents, or reduces the frequency, rate or extent of astrocyte differentiation.") -AnnotationAssertion( "down regulation of astrocyte differentiation") -AnnotationAssertion( "down-regulation of astrocyte differentiation") -AnnotationAssertion( "downregulation of astrocyte differentiation") -AnnotationAssertion( "inhibition of astrocyte differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048712") -AnnotationAssertion(rdfs:label "negative regulation of astrocyte differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of oligodendrocyte differentiation) - -AnnotationAssertion(Annotation( "GOC:vp") Annotation( "PMID:15139015") "Any process that modulates the frequency, rate or extent of oligodendrocyte differentiation.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048713") -AnnotationAssertion(rdfs:label "regulation of oligodendrocyte differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of oligodendrocyte differentiation) - -AnnotationAssertion(Annotation( "GOC:vp") Annotation( "PMID:15139015") "Any process that activates or increases the frequency, rate or extent of oligodendrocyte differentiation.") -AnnotationAssertion( "up regulation of oligodendrocyte differentiation") -AnnotationAssertion( "up-regulation of oligodendrocyte differentiation") -AnnotationAssertion( "upregulation of oligodendrocyte differentiation") -AnnotationAssertion( "activation of oligodendrocyte differentiation") -AnnotationAssertion( "stimulation of oligodendrocyte differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048714") -AnnotationAssertion(rdfs:label "positive regulation of oligodendrocyte differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of oligodendrocyte differentiation) - -AnnotationAssertion(Annotation( "GOC:vp") Annotation( "PMID:15139015") "Any process that stops, prevents, or reduces the frequency, rate or extent of oligodendrocyte differentiation.") -AnnotationAssertion( "down regulation of oligodendrocyte differentiation") -AnnotationAssertion( "down-regulation of oligodendrocyte differentiation") -AnnotationAssertion( "downregulation of oligodendrocyte differentiation") -AnnotationAssertion( "inhibition of oligodendrocyte differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048715") -AnnotationAssertion(rdfs:label "negative regulation of oligodendrocyte differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (tissue morphogenesis) AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:jid") "The process in which the anatomical structures of a tissue are generated and organized.") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0048729") AnnotationAssertion(rdfs:label "tissue morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (epidermis morphogenesis) - -AnnotationAssertion(Annotation( "GOC:jid") Annotation( "UBERON:0001003") "The process in which the anatomical structures of the epidermis are generated and organized. The epidermis is the outer epithelial layer of an animal, it may be a single layer that produces an extracellular material (e.g. the cuticle of arthropods) or a complex stratified squamous epithelium, as in the case of many vertebrate species.") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:kmv") Annotation( "GOC:rk") "hypodermis morphogenesis") -AnnotationAssertion( "GO:0048730") -AnnotationAssertion(rdfs:label "epidermis morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (system development) AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:jid") "The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.") @@ -90267,7 +26016,6 @@ AnnotationAssertion( "GO:0048731") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "system development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) @@ -90277,182 +26025,9 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:0048732") AnnotationAssertion(rdfs:label "gland development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) -# Class: (sebaceous gland development) - -AnnotationAssertion(Annotation( "GOC:jid") "The process whose specific outcome is the progression of the sebaceous gland over time, from its formation to the mature structure.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048733") -AnnotationAssertion(rdfs:label "sebaceous gland development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (haltere morphogenesis) - -AnnotationAssertion(Annotation( "GOC:jid") Annotation( "GOC:rc") "The process in which the anatomical structures of a haltere are generated and organized.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048735") -AnnotationAssertion(rdfs:label "haltere morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (appendage development) - -AnnotationAssertion(Annotation( "GOC:jid") Annotation( "GOC:rc") "The process whose specific outcome is the progression of an appendage over time, from its formation to the mature structure. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048736") -AnnotationAssertion(rdfs:label "appendage development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (imaginal disc-derived appendage development) - -AnnotationAssertion(Annotation( "GOC:jid") Annotation( "GOC:mtg_sensu") Annotation( "GOC:rc") "The process whose specific outcome is the progression of an appendage over time, from its formation in the imaginal disc to the mature structure. An appendage is an organ or part that is attached to the trunk of an organism.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048737") -AnnotationAssertion(rdfs:label "imaginal disc-derived appendage development") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - -# Class: (cardiac muscle tissue development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GOC:lm") "The process whose specific outcome is the progression of cardiac muscle over time, from its formation to the mature structure.") -AnnotationAssertion( "heart muscle development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048738") -AnnotationAssertion(rdfs:label "cardiac muscle tissue development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (skeletal muscle fiber development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:ef") Annotation( "GOC:jid") Annotation( "GOC:lm") Annotation( "GOC:mtg_muscle") "The process whose specific outcome is the progression of the skeletal muscle fiber over time, from its formation to the mature structure. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast.") -AnnotationAssertion( "skeletal muscle fibre development") -AnnotationAssertion( "skeletal myofiber development") -AnnotationAssertion( "skeletal myofibre development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048741") -AnnotationAssertion(rdfs:label "skeletal muscle fiber development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (regulation of skeletal muscle fiber development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GOC:mtg_muscle") Annotation( "GOC:sm") "Any process that modulates the frequency, rate or extent of skeletal muscle fiber development. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast.") -AnnotationAssertion( "regulation of skeletal muscle fibre development") -AnnotationAssertion( "regulation of skeletal myofiber development") -AnnotationAssertion( "regulation of skeletal myofibre development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048742") -AnnotationAssertion(rdfs:label "regulation of skeletal muscle fiber development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of skeletal muscle fiber development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GOC:lm") Annotation( "GOC:mtg_muscle") "Any process that activates, maintains or increases the rate of skeletal muscle fiber development. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast.") -AnnotationAssertion( "positive regulation of skeletal muscle fibre development") -AnnotationAssertion( "positive regulation of skeletal myofiber development") -AnnotationAssertion( "positive regulation of skeletal myofibre development") -AnnotationAssertion( "up regulation of skeletal muscle fiber development") -AnnotationAssertion( "up-regulation of skeletal muscle fiber development") -AnnotationAssertion( "upregulation of skeletal muscle fiber development") -AnnotationAssertion( "activation of skeletal muscle fiber development") -AnnotationAssertion( "stimulation of skeletal muscle fiber development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048743") -AnnotationAssertion(rdfs:label "positive regulation of skeletal muscle fiber development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of skeletal muscle fiber development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GOC:lm") Annotation( "GOC:mtg_muscle") "Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle fiber development. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast.") -AnnotationAssertion( "down regulation of skeletal muscle fiber development") -AnnotationAssertion( "down-regulation of skeletal muscle fiber development") -AnnotationAssertion( "downregulation of skeletal muscle fiber development") -AnnotationAssertion( "negative regulation of skeletal muscle fibre development") -AnnotationAssertion( "negative regulation of skeletal myofiber development") -AnnotationAssertion( "negative regulation of skeletal myofibre development") -AnnotationAssertion( "inhibition of skeletal muscle fiber development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048744") -AnnotationAssertion(rdfs:label "negative regulation of skeletal muscle fiber development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (smooth muscle tissue development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GOC:lm") "The process whose specific outcome is the progression of smooth muscle over time, from its formation to the mature structure.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048745") -AnnotationAssertion(rdfs:label "smooth muscle tissue development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (compound eye development) - -AnnotationAssertion(Annotation( "GOC:jid") Annotation( "GOC:mtg_sensu") Annotation( "Wikipedia:Eye") "The process whose specific outcome is the progression of the compound eye over time, from its formation to the mature structure. The compound eye is an organ of sight that contains multiple repeating units, often arranged hexagonally. Each unit has its own lens and photoreceptor cell(s) and can generate either a single pixelated image or multiple images, per eye.") -AnnotationAssertion( "GO:0007456") -AnnotationAssertion(Annotation( "PMID:11735386") "insect-type retina development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048749") -AnnotationAssertion(rdfs:label "compound eye development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (compound eye corneal lens morphogenesis) - -AnnotationAssertion(Annotation( "GOC:jid") "The process in which the anatomical structures of the compound eye corneal lens are generated and organized.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048750") -AnnotationAssertion(rdfs:label "compound eye corneal lens morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - -# Class: (semicircular canal morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") "The process in which the anatomical structures of the semicircular canals are generated and organized.") -AnnotationAssertion( "embryonic semicircular canal morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048752") -AnnotationAssertion(rdfs:label "semicircular canal morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (pigment granule organization) - -AnnotationAssertion(Annotation( "GOC:rc") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a pigment granule.") -AnnotationAssertion( "pigment granule organisation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:mah") "pigment granule organization and biogenesis") -AnnotationAssertion( "GO:0048753") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "pigment granule organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (branching morphogenesis of an epithelial tube) AnnotationAssertion(Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") "The process in which the anatomical structures of branches in an epithelial tube are generated and organized. A tube is a long hollow cylinder.") @@ -90460,30 +26035,10 @@ AnnotationAssertion( "GOC:dph") Annotation( "GOC:tb") "tubulogenesis") AnnotationAssertion( "GO:0048754") AnnotationAssertion(rdfs:label "branching morphogenesis of an epithelial tube") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (branching morphogenesis of a nerve) - -AnnotationAssertion(Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") "The process in which the anatomical structures of branches in a nerve are generated and organized. This term refers to an anatomical structure (nerve) not a cell (neuron).") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048755") -AnnotationAssertion(rdfs:label "branching morphogenesis of a nerve") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (mesenchymal cell differentiation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:jid") "The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal cell. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048762") -AnnotationAssertion(rdfs:label "mesenchymal cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (pigment granule) AnnotationAssertion(Annotation( "GOC:jid") Annotation( "GOC:mh") "A small, subcellular membrane-bounded vesicle containing pigment and/or pigment precursor molecules. Pigment granule biogenesis is poorly understood, as pigment granules are derived from multiple sources including the endoplasmic reticulum, coated vesicles, lysosomes, and endosomes.") @@ -90492,425 +26047,6 @@ AnnotationAssertion( "pigment granule") SubClassOf( ) -# Class: (tissue remodeling) - -AnnotationAssertion(Annotation( "GOC:ebc") "The reorganization or renovation of existing tissues. This process can either change the characteristics of a tissue such as in blood vessel remodeling, or result in the dynamic equilibrium of a tissue such as in bone remodeling.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048771") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "tissue remodeling") -SubClassOf( ) - -# Class: (hatching gland development) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:dh") Annotation( "GOC:jid") "The process whose specific outcome is the progression of the hatching gland over time, from its formation to the mature structure. The cells of the hatching gland contain enzymes responsible for solubilization of the egg chorion, facilitating the hatching process.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048785") -AnnotationAssertion(rdfs:label "hatching gland development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (pronephros development) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:mtg_kidney_jan10") Annotation( "PMID:10535314") Annotation( "PMID:15968585") Annotation( "PMID:18322540") Annotation( "XAO:00002000") Annotation( "ZFA:0000151") "The process whose specific outcome is the progression of the pronephros over time, from its formation to the mature structure. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life.") -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "pronephric kidney development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048793") -AnnotationAssertion(rdfs:label "pronephros development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (swim bladder development) - -AnnotationAssertion(Annotation( "GOC:mh") "The process whose specific outcome is the progression of the swim bladder over time, from its formation to the mature structure. The swim bladder is used by some fishes to maintain buoyancy and may function in addition as a sound producing organ, a sound receptor, and a respiratory organ.") -AnnotationAssertion( "gas bladder development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048794") -AnnotationAssertion(rdfs:label "swim bladder development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (swim bladder morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mh") "The process in which the anatomical structure of the swim bladder is generated and organized. The swim bladder is used by some fishes to maintain buoyancy and may function in addition as a sound producing organ, a sound receptor, and a respiratory organ.") -AnnotationAssertion( "gas bladder morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048795") -AnnotationAssertion(rdfs:label "swim bladder morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (swim bladder maturation) - -AnnotationAssertion(Annotation( "GOC:devbiol") "A developmental process, independent of morphogenetic (shape) change, that is required for a swim bladder to attain its fully functional state. The swim bladder is used by some fishes to maintain buoyancy and may function in addition as a sound producing organ, a sound receptor, and a respiratory organ.") -AnnotationAssertion( "gas bladder maturation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048796") -AnnotationAssertion(rdfs:label "swim bladder maturation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (swim bladder formation) - -AnnotationAssertion(Annotation( "GOC:mh") "The process that gives rise to the swim bladder. This process pertains to the initial formation of a structure from unspecified parts. The swim bladder is used by some fishes to maintain buoyancy and may function in addition as a sound producing organ, a sound receptor, and a respiratory organ.") -AnnotationAssertion( "gas bladder biosynthesis") -AnnotationAssertion( "gas bladder formation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048797") -AnnotationAssertion(rdfs:label "swim bladder formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (animal organ maturation) - -AnnotationAssertion(Annotation( "GOC:curators") "A developmental process, independent of morphogenetic (shape) change, that is required for an animal organ to attain its fully functional state. An organ is a tissue or set of tissues that work together to perform a specific function or functions.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048799") -AnnotationAssertion(rdfs:label "animal organ maturation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (antennal morphogenesis) - -AnnotationAssertion(Annotation( "GOC:jid") "The process in which the anatomical structures of the antenna are generated and organized.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048800") -AnnotationAssertion(rdfs:label "antennal morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (genitalia development) - -AnnotationAssertion(Annotation( "GOC:jid") "The process whose specific outcome is the progression of the genitalia over time, from its formation to the mature structure.") -AnnotationAssertion( "genital development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048806") -AnnotationAssertion(rdfs:label "genitalia development") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (male genitalia morphogenesis) - -AnnotationAssertion(Annotation( "GOC:ems") Annotation( "ISBN:0140512888") "The process in which the anatomical structures of male genitalia are generated and organized.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "male genital morphogenesis") -AnnotationAssertion( "GO:0048808") -AnnotationAssertion(rdfs:label "male genitalia morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (neuron projection morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mah") "The process in which the anatomical structures of a neuron projection are generated and organized. A neuron projection is any process extending from a neural cell, such as axons or dendrites.") -AnnotationAssertion( "neurite biosynthesis") -AnnotationAssertion( "neurite formation") -AnnotationAssertion( "neurite growth") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "neurite morphogenesis") -AnnotationAssertion( "GO:0048812") -AnnotationAssertion(rdfs:label "neuron projection morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (dendrite morphogenesis) - -AnnotationAssertion(Annotation( "GOC:aruk") Annotation( "GOC:bc") Annotation( "GOC:jl") Annotation( "ISBN:0198506732") Annotation( "PMID:22683681") "The process in which the anatomical structures of a dendrite are generated and organized.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048813") -AnnotationAssertion(rdfs:label "dendrite morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (regulation of dendrite morphogenesis) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of dendrite morphogenesis.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048814") -AnnotationAssertion(rdfs:label "regulation of dendrite morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (ocellus morphogenesis) - -AnnotationAssertion(Annotation( "http://fly.ebi.ac.uk/.bin/cvreport2?id=FBcv0004540") "The process in which the anatomical structures of the ocellus are generated and organized. The ocellus is a simple visual organ of insects.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048816") -AnnotationAssertion(rdfs:label "ocellus morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (negative regulation of hair follicle maturation) - -AnnotationAssertion(Annotation( "GOC:devbiol") "Any process that stops, prevents, or reduces the frequency, rate or extent of hair follicle maturation.") -AnnotationAssertion( "down regulation of hair follicle maturation") -AnnotationAssertion( "down-regulation of hair follicle maturation") -AnnotationAssertion( "downregulation of hair follicle maturation") -AnnotationAssertion( "inhibition of hair follicle maturation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048817") -AnnotationAssertion(rdfs:label "negative regulation of hair follicle maturation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (positive regulation of hair follicle maturation) - -AnnotationAssertion(Annotation( "GOC:devbiol") "Any process that activates or increases the frequency, rate or extent of hair follicle maturation.") -AnnotationAssertion( "up regulation of hair follicle maturation") -AnnotationAssertion( "up-regulation of hair follicle maturation") -AnnotationAssertion( "upregulation of hair follicle maturation") -AnnotationAssertion( "activation of hair follicle maturation") -AnnotationAssertion( "stimulation of hair follicle maturation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048818") -AnnotationAssertion(rdfs:label "positive regulation of hair follicle maturation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of hair follicle maturation) - -AnnotationAssertion(Annotation( "GOC:devbiol") "Any process that modulates the frequency, rate or extent of hair follicle maturation.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048819") -AnnotationAssertion(rdfs:label "regulation of hair follicle maturation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (hair follicle maturation) - -AnnotationAssertion(Annotation( "GOC:devbiol") "A developmental process, independent of morphogenetic (shape) change, that is required for a hair follicle to attain its fully functional state.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048820") -AnnotationAssertion(rdfs:label "hair follicle maturation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (erythrocyte development) - -AnnotationAssertion(Annotation( "GOC:devbiol") "The process whose specific outcome is the progression of an erythrocyte over time, from its formation to the mature structure.") -AnnotationAssertion(Annotation( "CL:0000232") "RBC development") -AnnotationAssertion(Annotation( "CL:0000232") "red blood cell development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048821") -AnnotationAssertion(rdfs:label "erythrocyte development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (enucleate erythrocyte development) - -AnnotationAssertion(Annotation( "GOC:devbiol") "The process aimed at the progression of an enucleate erythrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.") -AnnotationAssertion(Annotation( "CL:0000232") "enucleate RBC development") -AnnotationAssertion(Annotation( "CL:0000232") "enucleate red blood cell development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048822") -AnnotationAssertion(rdfs:label "enucleate erythrocyte development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (nucleate erythrocyte development) - -AnnotationAssertion(Annotation( "GOC:devbiol") "The process aimed at the progression of a nucleate erythrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.") -AnnotationAssertion(Annotation( "CL:0000232") "nucleate RBC development") -AnnotationAssertion(Annotation( "CL:0000232") "nucleate red blood cell development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048823") -AnnotationAssertion(rdfs:label "nucleate erythrocyte development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (inner ear development) - -AnnotationAssertion(Annotation( "GOC:sr") "The process whose specific outcome is the progression of the inner ear over time, from its formation to the mature structure.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048839") -AnnotationAssertion(rdfs:label "inner ear development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (otolith development) - -AnnotationAssertion(Annotation( "GOC:sr") "The process whose specific outcome is the progression of the otolith over time, from its formation to the mature structure.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048840") -AnnotationAssertion(rdfs:label "otolith development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - -# Class: (artery morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dsf") Annotation( "PMID:16740480") "The process in which the anatomical structures of arterial blood vessels are generated and organized. Arteries are blood vessels that transport blood from the heart to the body and its organs.") -AnnotationAssertion( "arterial morphogenesis") -AnnotationAssertion(Annotation( "GOC:mtg_heart") "arteriogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048844") -AnnotationAssertion(rdfs:label "artery morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (venous blood vessel morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dsf") Annotation( "PMID:16740480") "The process in which the anatomical structures of venous blood vessels are generated and organized. Veins are blood vessels that transport blood from the body and its organs to the heart.") -AnnotationAssertion( "vein morphogenesis") -AnnotationAssertion( "venous morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048845") -AnnotationAssertion(rdfs:label "venous blood vessel morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (adenohypophysis formation) - -AnnotationAssertion(Annotation( "GOC:cvs") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") "The process that gives rise to adenohypophysis. This process pertains to the initial formation of a structure from unspecified parts. The adenohypophysis is the anterior part of the pituitary. It secretes a variety of hormones and its function is regulated by the hypothalamus.") -AnnotationAssertion( "adenophysis biosynthesis") -AnnotationAssertion( "adenophysis formation") -AnnotationAssertion( "anterior pituitary biosynthesis") -AnnotationAssertion( "anterior pituitary formation") -AnnotationAssertion( "anterior pituitary gland biosynthesis") -AnnotationAssertion( "anterior pituitary gland formation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048847") -AnnotationAssertion(rdfs:label "adenohypophysis formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (neurohypophysis morphogenesis) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") "The process in which the anatomical structures of the neurohypophysis are generated and organized. The neurohypophysis is the part of the pituitary gland that secretes hormones involved in blood pressure regulation.") -AnnotationAssertion( "neurophysis morphogenesis") -AnnotationAssertion( "posterior pituitary gland morphogenesis") -AnnotationAssertion( "posterior pituitary morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048848") -AnnotationAssertion(rdfs:label "neurohypophysis morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (neurohypophysis formation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") "The process that gives rise to neurohypophysis. This process pertains to the initial formation of a structure from unspecified parts. The neurohypophysis is the part of the pituitary gland that secretes hormones involved in blood pressure regulation.") -AnnotationAssertion( "neurophysis biosynthesis") -AnnotationAssertion( "neurophysis formation") -AnnotationAssertion( "posterior pituitary biosynthesis") -AnnotationAssertion( "posterior pituitary formation") -AnnotationAssertion( "posterior pituitary gland biosynthesis") -AnnotationAssertion( "posterior pituitary gland formation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048849") -AnnotationAssertion(rdfs:label "neurohypophysis formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (hypophysis morphogenesis) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") "The process in which the anatomical structures of the hypophysis are generated and organized. The pituitary gland is an endocrine gland that secretes hormones that regulate many other glands.") -AnnotationAssertion( "pituitary gland morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048850") -AnnotationAssertion(rdfs:label "hypophysis morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (hypophysis formation) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") "The process in which the anatomical structures of the hypophysis are generated and organized. The hypophysis is an endocrine gland that secretes hormones that regulate many other glands.") -AnnotationAssertion( "hypophysis biosynthesis") -AnnotationAssertion( "pituitary gland biosynthesis") -AnnotationAssertion( "pituitary gland formation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048851") -AnnotationAssertion(rdfs:label "hypophysis formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (diencephalon morphogenesis) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "ISBN:0838580343") "The process in which the anatomical structures of the diencephalon are generated and organized. The diencephalon is the paired caudal parts of the prosencephalon from which the thalamus, hypothalamus, epithalamus and subthalamus are derived; these regions regulate autonomic, visceral and endocrine function, and process information directed to the cerebral cortex.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048852") -AnnotationAssertion(rdfs:label "diencephalon morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (forebrain morphogenesis) - -AnnotationAssertion(Annotation( "GOC:cvs") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") "The process in which the anatomical structures of the forebrain are generated and organized. The forebrain is the anterior of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes especially the cerebral hemispheres, the thalamus, and the hypothalamus and especially in higher vertebrates is the main control center for sensory and associative information processing, visceral functions, and voluntary motor functions).") -AnnotationAssertion( "prosencephalon morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048853") -AnnotationAssertion(rdfs:label "forebrain morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (brain morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dgh") Annotation( "GOC:jid") "The process in which the anatomical structures of the brain are generated and organized. The brain is one of the two components of the central nervous system and is the center of thought and emotion. It is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048854") -AnnotationAssertion(rdfs:label "brain morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (adenohypophysis morphogenesis) - -AnnotationAssertion(Annotation( "GOC:cvs") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") "The process in which the anatomical structures of the adenohypophysis are generated and organized. The adenohypophysis is the anterior part of the pituitary. It secretes a variety of hormones and its function is regulated by the hypothalamus.") -AnnotationAssertion( "adenophysis morphogenesis") -AnnotationAssertion( "anterior pituitary gland morphogenesis") -AnnotationAssertion( "anterior pituitary morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048855") -AnnotationAssertion(rdfs:label "adenohypophysis morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (anatomical structure development) AnnotationAssertion(Annotation( "GO_REF:0000021") "The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.") @@ -90921,70 +26057,8 @@ AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "anatomical structure development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (neural nucleus development) - -AnnotationAssertion(Annotation( "GO_REF:0000021") "The biological process whose specific outcome is the progression of a neural nucleus from its initial condition to its mature state. A neural nucleus is an anatomical structure consisting of a discrete aggregate of neuronal soma.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048857") -AnnotationAssertion(rdfs:label "neural nucleus development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (cell projection morphogenesis) - -AnnotationAssertion(Annotation( "GO_REF:0000021") "The process in which the anatomical structures of a cell projection are generated and organized.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048858") -AnnotationAssertion(rdfs:label "cell projection morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (formation of anatomical boundary) - -AnnotationAssertion(Annotation( "GO_REF:0000021") "The process in which the limits of an anatomical structure are generated. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048859") -AnnotationAssertion(rdfs:label "formation of anatomical boundary") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (glioblast division) - -AnnotationAssertion(Annotation( "GOC:devbiol") "The process resulting in the physical partitioning and separation of a glioblast into daughter cells.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048860") -AnnotationAssertion(rdfs:label "glioblast division") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (stem cell differentiation) - -AnnotationAssertion(Annotation( "CL:0000034") Annotation( "GOC:isa_complete") "The process in which a relatively unspecialized cell acquires specialized features of a stem cell. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells.") -AnnotationAssertion( ) -AnnotationAssertion( "Wikipedia:Stem_cell_differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048863") -AnnotationAssertion(rdfs:label "stem cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) -DisjointClasses( ObjectSomeValuesFrom( )) - -# Class: (stem cell development) - -AnnotationAssertion(Annotation( "CL:0000034") Annotation( "GOC:isa_complete") "The process whose specific outcome is the progression of the stem cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to its specific fate.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048864") -AnnotationAssertion(rdfs:label "stem cell development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (cellular developmental process) AnnotationAssertion(Annotation( "GOC:isa_complete") "A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition.") @@ -91019,939 +26093,14 @@ AnnotationAssertion(rdfs:label "mult SubClassOf( ) SubClassOf( ) -# Class: (homeostasis of number of cells) - -AnnotationAssertion(Annotation( "GOC:isa_complete") "Any biological process involved in the maintenance of the steady-state number of cells within a population of cells.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/24218"^^xsd:anyURI) -AnnotationAssertion( "cell population homeostasis") -AnnotationAssertion(Annotation( "GOC:dph") "homeostasis of cell number") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048872") -AnnotationAssertion(rdfs:label "homeostasis of number of cells") -SubClassOf( ) - -# Class: (homeostasis of number of cells within a tissue) - -AnnotationAssertion(Annotation( "GOC:isa_complete") "Any biological process involved in the maintenance of the steady-state number of cells within a population of cells in a tissue.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048873") -AnnotationAssertion(rdfs:label "homeostasis of number of cells within a tissue") -SubClassOf( ) -SubClassOf( ) - -# Class: (chemical homeostasis) - -AnnotationAssertion(Annotation( "GOC:isa_complete") "Any biological process involved in the maintenance of an internal steady state of a chemical.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048878") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "chemical homeostasis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (sensory system development) - -AnnotationAssertion(Annotation( "GOC:dgh") "The process whose specific outcome is the progression of a sensory system over time from its formation to the mature structure.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048880") -AnnotationAssertion(rdfs:label "sensory system development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (mechanosensory lateral line system development) - -AnnotationAssertion(Annotation( "ISBN:0125296509") "The process whose specific outcome is the progression of the mechanosensory lateral line system over time, from its formation to the mature structure. The mechanosensory lateral line system consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head and body of all fishes and most amphibians. The neuromasts are innervated by several lateral line nerves, which project primarily to the hindbrain. The mechanosensory lateral line system is stimulated by local water displacements and vibrations, and detects propulsion of the fish through the water, as well as facilitating shoaling, prey capture, and predator and obstacle avoidance.") -AnnotationAssertion(Annotation( "ISBN:0125296509") "LL system development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048881") -AnnotationAssertion(rdfs:label "mechanosensory lateral line system development") -SubClassOf( ) - -# Class: (lateral line development) - -AnnotationAssertion(Annotation( "ISBN:0125296509") "The process whose specific outcome is the progression of the lateral line over time, from its formation to the mature structure. The lateral line consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head and body of all fishes and most amphibians. The lateral line develops from cranial ectodermal placodes situated behind the ear and between the eye and ear.") -AnnotationAssertion( "LL development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048882") -AnnotationAssertion(rdfs:label "lateral line development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (neuromast development) - -AnnotationAssertion(Annotation( "ISBN:0125296509") "The process whose specific outcome is the progression of the neuromast over time, from its formation to the mature structure. The neuromast is the sensory organ of the lateral line and is composed of a population of sensory hair cells, and nonsensory supporting cells and mantle cells. Neuromasts are located superficially on the epithelium or in lateral line canals.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048884") -AnnotationAssertion(rdfs:label "neuromast development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (neuromast hair cell differentiation) - -AnnotationAssertion(Annotation( "CL:0000856") Annotation( "ISBN:0125296509") "The process in which a relatively unspecialized cell acquires specialized features of a neuromast hair cell. Hair cells are the sensory receptors of the neuromast and are located in a portion of the neuromast called the sensory strip. Each hair cell of the neuromast is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. There are approximately seven hair cells within each neuromast, with each hair cell innervated by afferent and efferent neurons.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048886") -AnnotationAssertion(rdfs:label "neuromast hair cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (lateral line ganglion development) - -AnnotationAssertion(Annotation( "ISBN:0125296509") Annotation( "ISBN:0387968377") "The process whose specific outcome is the progression of the lateral line ganglion over time, from its formation to the mature structure. The lateral line ganglion develops from cranial ectodermal placodes situated between the eye and ear and behind the ear.") -AnnotationAssertion( "gLL ganglion development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048890") -AnnotationAssertion(rdfs:label "lateral line ganglion development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (lateral line ganglion neuron differentiation) - -AnnotationAssertion(Annotation( "PMID:15018940") "The process in which a relatively unspecialized cell acquires specialized features of a lateral line ganglion neuron.") -AnnotationAssertion( "gLL neuron differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048891") -AnnotationAssertion(rdfs:label "lateral line ganglion neuron differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (lateral line nerve development) - -AnnotationAssertion(Annotation( "ISBN:0125296509") "The process whose specific outcome is the progression of the lateral line nerve over time, form its formation to the mature structure. Lateral line nerves project primarily to an octavolateralis column in the hindbrain that consists of the medial octavolateralis nucleus (MON), the caudal octavolateralis nucleus, and the magnocellular nucleus.") -AnnotationAssertion( "nLL development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048892") -AnnotationAssertion(rdfs:label "lateral line nerve development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (lateral line nerve glial cell differentiation) - -AnnotationAssertion(Annotation( "PMID:12062041") "The process in which a relatively unspecialized cell acquires specialized features of a glial cell in a lateral line nerve.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048895") -AnnotationAssertion(rdfs:label "lateral line nerve glial cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (lateral line nerve glial cell migration) - -AnnotationAssertion(Annotation( "PMID:12062041") "The movement of a glial cell along the axons in a lateral line nerve.") -AnnotationAssertion( "glial cell migration in lateral line nerve") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048896") -AnnotationAssertion(rdfs:label "lateral line nerve glial cell migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (anterior lateral line system development) - -AnnotationAssertion(Annotation( "ISBN:0125296509") Annotation( "PMID:15018940") "The process whose specific outcome is the progression of the anterior lateral line system over time, from its formation to the mature structure. The anterior lateral line system develops from cranial ectodermal placodes, situated between the eye and the ear, that give rise to both the neuromasts and the anterior lateral line sensory nerves that innervate the neuromasts. The anterior lateral line system consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head of all fishes and most amphibians and are innervated by several lateral line nerves, which project to the hindbrain. The anterior lateral line system is stimulated by local water displacements and vibrations, and detects propulsion of the fish through the water, as well as facilitating shoaling, prey capture, and predator and obstacle avoidance.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "ALL system development") -AnnotationAssertion( "GO:0048898") -AnnotationAssertion(rdfs:label "anterior lateral line system development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (anterior lateral line development) - -AnnotationAssertion(Annotation( "ISBN:0125296509") "The process whose specific outcome is the progression of the anterior lateral line over time, from its formation to the mature structure. The anterior lateral line consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head of all fishes and most amphibians. The anterior lateral line develops from cranial ectodermal placodes situated between the eye and ear.") -AnnotationAssertion( "anterior LL development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048899") -AnnotationAssertion(rdfs:label "anterior lateral line development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (anterior lateral line neuromast development) - -AnnotationAssertion(Annotation( "ISBN:0125296509") "The process whose specific outcome is the progression of the anterior lateral line neuromast over time, from its formation to the mature structure. The neuromast is the sensory receptor of the anterior lateral line system and is composed of a population of sensory hair cells, and nonsensory supporting cells and mantle cells. Neuromast are located superficially on the epithelium or in lateral line canals.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048901") -AnnotationAssertion(rdfs:label "anterior lateral line neuromast development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (anterior lateral line neuromast hair cell differentiation) - -AnnotationAssertion(Annotation( "ISBN:0125296509") Annotation( "ISBN:0387968377") "The process in which a relatively unspecialized cell acquires specialized features of an anterior lateral line neuromast hair cell. Neuromast hair cells are the sensory receptors of the neuromast and are located in a portion of the neuromast called the sensory strip. Each hair cell of the neuromast is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. There are approximately seven hair cells within each neuromast, with each hair cell innervated by afferent and efferent neurons.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048903") -AnnotationAssertion(rdfs:label "anterior lateral line neuromast hair cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (anterior lateral line ganglion development) - -AnnotationAssertion(Annotation( "ISBN:0125296509") "The process whose specific outcome is the progression of the anterior lateral line ganglion over time, from its formation to the mature structure. The anterior lateral line ganglion develops from cranial ectodermal placodes situated between the eye and ear.") -AnnotationAssertion( "gALL development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048907") -AnnotationAssertion(rdfs:label "anterior lateral line ganglion development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (anterior lateral line nerve development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0125296509") "The process whose specific outcome is the progression of the anterior lateral line nerve over time, form its formation to the mature structure. The anterior lateral line nerve contains efferent axons that innervate hair cells of the ALL and afferent axons that project to an octavolateralis column in the hindbrain. The octavolateralis column consists of the medial octavolateralis nucleus (MON), the caudal octavolateralis nucleus, and the magnocellular nucleus.") -AnnotationAssertion( "GO:0021734") -AnnotationAssertion( "ALLN development") -AnnotationAssertion( "nALL development") -AnnotationAssertion( "rostral lateral line nerve development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048909") -AnnotationAssertion(rdfs:label "anterior lateral line nerve development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (anterior lateral line nerve glial cell differentiation) - -AnnotationAssertion(Annotation( "PMID:15832385") "The process in which a relatively unspecialized cell acquires specialized features of a glial cell in the anterior lateral line nerve.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048913") -AnnotationAssertion(rdfs:label "anterior lateral line nerve glial cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (posterior lateral line system development) - -AnnotationAssertion(Annotation( "ISBN:0125296509") Annotation( "PMID:15018940") "The process whose specific outcome is the progression of the posterior lateral line system over time, from its formation to the mature structure. The posterior lateral line system develops from cranial ectodermal placodes, situated behind the ear, that give rise to both the neuromasts and the posterior lateral line sensory nerves that innervate the neuromasts. The posterior lateral line system consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head of all fishes and most amphibians. The neuromasts are innervated by several lateral line nerves, which project primarily to the hindbrain. The posterior mechanosensory lateral line system is stimulated by local water displacements and vibrations, and detects propulsion of the fish through the water, as well as facilitating shoaling, prey capture, and predator and obstacle avoidance.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "PLL") -AnnotationAssertion( "GO:0048915") -AnnotationAssertion(rdfs:label "posterior lateral line system development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (posterior lateral line development) - -AnnotationAssertion(Annotation( "ISBN:0125296509") "The process whose specific outcome is the progression of the posterior lateral line over time, from its formation to the mature structure. The posterior lateral line consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the body and trunk of all fishes and most amphibians. The posterior lateral line develops from cranial ectodermal placodes situated behind the ear.") -AnnotationAssertion( "PLL development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048916") -AnnotationAssertion(rdfs:label "posterior lateral line development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (posterior lateral line ganglion development) - -AnnotationAssertion(Annotation( "ISBN:0125296509") Annotation( "ISBN:0387968377") "The process whose specific outcome is the progression of the posterior lateral line ganglion over time, from its formation to the mature structure. The posterior lateral line ganglion develops from cranial ectodermal placodes situated behind the ear.") -AnnotationAssertion( "gPLL development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048917") -AnnotationAssertion(rdfs:label "posterior lateral line ganglion development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (posterior lateral line nerve development) - -AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0125296509") "The process whose specific outcome is the progression of the posterior lateral line nerve over time, from its formation to the mature structure. The posterior lateral line nerve innervates hair cells of the PLL and projects to an octavolateralis column in the hindbrain that consists of the medial octavolateralis nucleus (MON), the caudal octavolateralis nucleus, and the magnocellular nucleus.") -AnnotationAssertion( "GO:0021733") -AnnotationAssertion( "PLLN development") -AnnotationAssertion( "caudal lateral line nerve development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048918") -AnnotationAssertion(rdfs:label "posterior lateral line nerve development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (posterior lateral line neuromast development) - -AnnotationAssertion(Annotation( "ISBN:0125296509") "The process whose specific outcome is the progression of the posterior lateral line neuromast over time, from its formation to the mature structure. The neuromast is the sensory receptor of the anterior lateral line system and is composed of a population of sensory hair cells, and nonsensory supporting cells and mantle cells. Neuromast are located superficially on the epithelium or in lateral line canals.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048919") -AnnotationAssertion(rdfs:label "posterior lateral line neuromast development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (posterior lateral line neuromast hair cell differentiation) - -AnnotationAssertion(Annotation( "ISBN:0125296509") "The process in which a relatively unspecialized cell acquires specialized features of a posterior lateral line neuromast hair cell. (N.B. This may be development of neuromast hair cell type or a set of cell of neuromast hair cell type. This will involve the change of a cell or set of cells from one cell identity to another). Hair cells are the sensory receptors of the neuromast and are located in a portion of the neuromast called the sensory strip. Each hair cell of the neuromast is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. There are approximately seven hair cells within each neuromast, with each hair cell innervated by afferent and efferent neurons.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048923") -AnnotationAssertion(rdfs:label "posterior lateral line neuromast hair cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (lateral line system development) - -AnnotationAssertion(Annotation( "GOC:dgh") Annotation( "ISBN:0125296509") "The process whose specific outcome is the progression of the lateral line system over time, from its formation to the mature structure. The lateral line system is a network of sensory organs (neuromasts) and lateral line nerves located superficially on the skin or just under the skin in fluid-filled canals on the head and body of all fishes and most amphibians. The lateral line system develops from cranial ectodermal placodes situated between the eye and ear.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048925") -AnnotationAssertion(rdfs:label "lateral line system development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (posterior lateral line ganglion neuron differentiation) - -AnnotationAssertion(Annotation( "PMID:15018940") "The process in which a relatively unspecialized cell acquires specialized features of a neuron of the posterior lateral line ganglion.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048928") -AnnotationAssertion(rdfs:label "posterior lateral line ganglion neuron differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (posterior lateral line nerve glial cell differentiation) - -AnnotationAssertion(Annotation( "PMID:15832385") "The process in which a relatively unspecialized cell acquires specialized features of a glial cell in the posterior lateral line nerve.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048931") -AnnotationAssertion(rdfs:label "posterior lateral line nerve glial cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (peripheral nervous system neuron differentiation) - -AnnotationAssertion(Annotation( "GOC:dgh") "The process in which a relatively unspecialized cell acquires specialized features of a neuron whose cell body resides in the peripheral nervous system.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048934") -AnnotationAssertion(rdfs:label "peripheral nervous system neuron differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (peripheral nervous system neuron development) - -AnnotationAssertion(Annotation( "GOC:dgh") "The process whose specific outcome is the progression of a neuron whose cell body is located in the peripheral nervous system, from initial commitment of the cell to a neuronal fate, to the fully functional differentiated neuron.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048935") -AnnotationAssertion(rdfs:label "peripheral nervous system neuron development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (lateral line nerve glial cell development) - -AnnotationAssertion(Annotation( "GOC:dgh") "The process aimed at the progression of a lateral line glial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048937") -AnnotationAssertion(rdfs:label "lateral line nerve glial cell development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (lateral line nerve glial cell morphogenesis involved in differentiation) - -AnnotationAssertion(Annotation( "GOC:dgh") "The process in which the structure of a glial cell in a lateral line nerve is generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a glial cell in a lateral line nerve.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048938") -AnnotationAssertion(rdfs:label "lateral line nerve glial cell morphogenesis involved in differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (anterior lateral line nerve glial cell development) - -AnnotationAssertion(Annotation( "GOC:dgh") "The process aimed at the progression of a glial cell in the anterior lateral line nerve over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048939") -AnnotationAssertion(rdfs:label "anterior lateral line nerve glial cell development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (anterior lateral line nerve glial cell morphogenesis involved in differentiation) - -AnnotationAssertion(Annotation( "GOC:dgh") "The process in which the structures of a glial cell in the anterior lateral line nerve are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a glial cell in the anterior lateral line nerve.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048940") -AnnotationAssertion(rdfs:label "anterior lateral line nerve glial cell morphogenesis involved in differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (posterior lateral line nerve glial cell development) - -AnnotationAssertion(Annotation( "GOC:dgh") "The process aimed at the progression of a glial cell in the posterior lateral line nerve over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048941") -AnnotationAssertion(rdfs:label "posterior lateral line nerve glial cell development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (posterior lateral line nerve glial cell morphogenesis involved in differentiation) - -AnnotationAssertion(Annotation( "GOC:dgh") "The process in which the structures of a glial cell in the posterior lateral line nerve are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a glial cell in the posterior lateral line nerve.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048942") -AnnotationAssertion(rdfs:label "posterior lateral line nerve glial cell morphogenesis involved in differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (chromosome localization) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process in which a chromosome is transported to, or maintained in, a specific location.") -AnnotationAssertion(Annotation( "GOC:mah") "chromosome localisation") -AnnotationAssertion( "establishment and maintenance of chromosome localization") -AnnotationAssertion( "establishment and maintenance of chromosome position") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0050000") -AnnotationAssertion(rdfs:label "chromosome localization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (catecholamine secretion) - -AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:ef") "The regulated release of catecholamines by a cell. The catecholamines are a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0050432") -AnnotationAssertion(rdfs:label "catecholamine secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of catecholamine secretion) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of the regulated release of catecholamines.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0050433") -AnnotationAssertion(rdfs:label "regulation of catecholamine secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (chondroitin sulfate proteoglycan biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways resulting in the formation of chondroitin sulfate proteoglycan, any glycoprotein whose glycosaminoglycan units are chondroitin sulfate. Chondroitin sulfates are a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues; the repeat units consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate.") -AnnotationAssertion( "chondroitin sulfate proteoglycan anabolism") -AnnotationAssertion( "chondroitin sulfate proteoglycan biosynthesis") -AnnotationAssertion( "chondroitin sulfate proteoglycan formation") -AnnotationAssertion( "chondroitin sulfate proteoglycan synthesis") -AnnotationAssertion( "chondroitin sulphate proteoglycan biosynthesis") -AnnotationAssertion( "chondroitin sulphate proteoglycan biosynthetic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0050650") -AnnotationAssertion(rdfs:label "chondroitin sulfate proteoglycan biosynthetic process") -SubClassOf( ) -SubClassOf( ) - -# Class: (chondroitin sulfate proteoglycan metabolic process) - -AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways involving chondroitin sulfate proteoglycan, any glycoprotein whose glycosaminoglycan units are chondroitin sulfate. Chondroitin sulfates are a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues; the repeat units consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate.") -AnnotationAssertion( "chondroitin sulfate proteoglycan metabolism") -AnnotationAssertion( "chondroitin sulphate proteoglycan metabolic process") -AnnotationAssertion( "chondroitin sulphate proteoglycan metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0050654") -AnnotationAssertion(rdfs:label "chondroitin sulfate proteoglycan metabolic process") -SubClassOf( ) - -# Class: (nucleic acid transport) - -AnnotationAssertion(Annotation( "GOC:ai") Annotation( "ISBN:0198506732") "The directed movement of nucleic acids, single or double-stranded polynucleotides involved in the storage, transmission and transfer of genetic information, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0050657") -AnnotationAssertion(rdfs:label "nucleic acid transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (RNA transport) - -AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of RNA, ribonucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0050658") -AnnotationAssertion(rdfs:label "RNA transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of lymphocyte proliferation) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of lymphocyte proliferation.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0050670") -AnnotationAssertion(rdfs:label "regulation of lymphocyte proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of lymphocyte proliferation) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the rate or extent of lymphocyte proliferation.") -AnnotationAssertion( "up regulation of lymphocyte proliferation") -AnnotationAssertion( "up-regulation of lymphocyte proliferation") -AnnotationAssertion( "upregulation of lymphocyte proliferation") -AnnotationAssertion( "activation of lymphocyte proliferation") -AnnotationAssertion( "stimulation of lymphocyte proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0050671") -AnnotationAssertion(rdfs:label "positive regulation of lymphocyte proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of lymphocyte proliferation) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents or reduces the rate or extent of lymphocyte proliferation.") -AnnotationAssertion( "down regulation of lymphocyte proliferation") -AnnotationAssertion( "down-regulation of lymphocyte proliferation") -AnnotationAssertion( "downregulation of lymphocyte proliferation") -AnnotationAssertion( "inhibition of lymphocyte proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0050672") -AnnotationAssertion(rdfs:label "negative regulation of lymphocyte proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - # Class: (epithelial cell proliferation) AnnotationAssertion(Annotation( "ISBN:0721662544") "The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population. Epithelial cells make up the epithelium, the covering of internal and external surfaces of the body, including the lining of vessels and other small cavities. It consists of cells joined by small amounts of cementing substances.") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0050673") AnnotationAssertion(rdfs:label "epithelial cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (urothelial cell proliferation) - -AnnotationAssertion(Annotation( "ISBN:0721662544") "The multiplication or reproduction of urothelial cells, resulting in the expansion of a cell population. Urothelial cells make up a layer of transitional epithelium in the wall of the bladder, ureter, and renal pelvis, external to the lamina propria.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0050674") -AnnotationAssertion(rdfs:label "urothelial cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of urothelial cell proliferation) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of urothelial cell proliferation.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0050675") -AnnotationAssertion(rdfs:label "regulation of urothelial cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of urothelial cell proliferation) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents or reduces the rate or extent of urothelial cell proliferation.") -AnnotationAssertion( "down regulation of urothelial cell proliferation") -AnnotationAssertion( "down-regulation of urothelial cell proliferation") -AnnotationAssertion( "downregulation of urothelial cell proliferation") -AnnotationAssertion( "inhibition of urothelial cell proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0050676") -AnnotationAssertion(rdfs:label "negative regulation of urothelial cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of urothelial cell proliferation) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the rate or extent of urothelial cell proliferation.") -AnnotationAssertion( "up regulation of urothelial cell proliferation") -AnnotationAssertion( "up-regulation of urothelial cell proliferation") -AnnotationAssertion( "upregulation of urothelial cell proliferation") -AnnotationAssertion( "activation of urothelial cell proliferation") -AnnotationAssertion( "stimulation of urothelial cell proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0050677") -AnnotationAssertion(rdfs:label "positive regulation of urothelial cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of epithelial cell proliferation) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of epithelial cell proliferation.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0050678") -AnnotationAssertion(rdfs:label "regulation of epithelial cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (positive regulation of epithelial cell proliferation) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the rate or extent of epithelial cell proliferation.") -AnnotationAssertion( "up regulation of epithelial cell proliferation") -AnnotationAssertion( "up-regulation of epithelial cell proliferation") -AnnotationAssertion( "upregulation of epithelial cell proliferation") -AnnotationAssertion( "activation of epithelial cell proliferation") -AnnotationAssertion( "stimulation of epithelial cell proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0050679") -AnnotationAssertion(rdfs:label "positive regulation of epithelial cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of epithelial cell proliferation) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents or reduces the rate or extent of epithelial cell proliferation.") -AnnotationAssertion( "down regulation of epithelial cell proliferation") -AnnotationAssertion( "down-regulation of epithelial cell proliferation") -AnnotationAssertion( "downregulation of epithelial cell proliferation") -AnnotationAssertion( "inhibition of epithelial cell proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0050680") -AnnotationAssertion(rdfs:label "negative regulation of epithelial cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of protein secretion) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of the controlled release of a protein from a cell.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0050708") -AnnotationAssertion(rdfs:label "regulation of protein secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of protein secretion) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a protein from a cell.") -AnnotationAssertion( "down regulation of protein secretion") -AnnotationAssertion( "down-regulation of protein secretion") -AnnotationAssertion( "downregulation of protein secretion") -AnnotationAssertion( "inhibition of protein secretion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0050709") -AnnotationAssertion(rdfs:label "negative regulation of protein secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of protein secretion) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of the controlled release of a protein from a cell.") -AnnotationAssertion( "up regulation of protein secretion") -AnnotationAssertion( "up-regulation of protein secretion") -AnnotationAssertion( "upregulation of protein secretion") -AnnotationAssertion( "activation of protein secretion") -AnnotationAssertion( "stimulation of protein secretion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0050714") -AnnotationAssertion(rdfs:label "positive regulation of protein secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of inflammatory response) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of the inflammatory response, the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0050727") -AnnotationAssertion(rdfs:label "regulation of inflammatory response") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of inflammatory response) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of the inflammatory response.") -AnnotationAssertion( "GO:0030236") -AnnotationAssertion( "anti-inflammatory response") -AnnotationAssertion( "down regulation of inflammatory response") -AnnotationAssertion( "down-regulation of inflammatory response") -AnnotationAssertion( "downregulation of inflammatory response") -AnnotationAssertion( "inhibition of inflammatory response") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0050728") -AnnotationAssertion(rdfs:label "negative regulation of inflammatory response") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of inflammatory response) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of the inflammatory response.") -AnnotationAssertion( "up regulation of inflammatory response") -AnnotationAssertion( "up-regulation of inflammatory response") -AnnotationAssertion( "upregulation of inflammatory response") -AnnotationAssertion( "activation of inflammatory response") -AnnotationAssertion( "stimulation of inflammatory response") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0050729") -AnnotationAssertion(rdfs:label "positive regulation of inflammatory response") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of peptidyl-tyrosine phosphorylation) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0050730") -AnnotationAssertion(rdfs:label "regulation of peptidyl-tyrosine phosphorylation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of peptidyl-tyrosine phosphorylation) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine.") -AnnotationAssertion( "up regulation of peptidyl-tyrosine phosphorylation") -AnnotationAssertion( "up-regulation of peptidyl-tyrosine phosphorylation") -AnnotationAssertion( "upregulation of peptidyl-tyrosine phosphorylation") -AnnotationAssertion( "activation of peptidyl-tyrosine phosphorylation") -AnnotationAssertion( "stimulation of peptidyl-tyrosine phosphorylation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0050731") -AnnotationAssertion(rdfs:label "positive regulation of peptidyl-tyrosine phosphorylation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of peptidyl-tyrosine phosphorylation) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine.") -AnnotationAssertion( "down regulation of peptidyl-tyrosine phosphorylation") -AnnotationAssertion( "down-regulation of peptidyl-tyrosine phosphorylation") -AnnotationAssertion( "downregulation of peptidyl-tyrosine phosphorylation") -AnnotationAssertion( "inhibition of peptidyl-tyrosine phosphorylation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0050732") -AnnotationAssertion(rdfs:label "negative regulation of peptidyl-tyrosine phosphorylation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of lipoprotein metabolic process) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving lipoproteins, any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids.") -AnnotationAssertion( "regulation of lipoprotein metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0050746") -AnnotationAssertion(rdfs:label "regulation of lipoprotein metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (positive regulation of lipoprotein metabolic process) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving lipoproteins, any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids.") -AnnotationAssertion( "positive regulation of lipoprotein metabolism") -AnnotationAssertion( "up regulation of lipoprotein metabolic process") -AnnotationAssertion( "up-regulation of lipoprotein metabolic process") -AnnotationAssertion( "upregulation of lipoprotein metabolic process") -AnnotationAssertion( "activation of lipoprotein metabolic process") -AnnotationAssertion( "stimulation of lipoprotein metabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0050747") -AnnotationAssertion(rdfs:label "positive regulation of lipoprotein metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (negative regulation of lipoprotein metabolic process) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving lipoproteins, any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids.") -AnnotationAssertion( "down regulation of lipoprotein metabolic process") -AnnotationAssertion( "down-regulation of lipoprotein metabolic process") -AnnotationAssertion( "downregulation of lipoprotein metabolic process") -AnnotationAssertion( "negative regulation of lipoprotein metabolism") -AnnotationAssertion( "inhibition of lipoprotein metabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0050748") -AnnotationAssertion(rdfs:label "negative regulation of lipoprotein metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of phagocytosis) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of phagocytosis, the process in which phagocytes engulf external particulate material.") -AnnotationAssertion( ) -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0050764") -AnnotationAssertion(rdfs:label "regulation of phagocytosis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) -SubClassOf( ObjectSomeValuesFrom( )) -DisjointClasses( ObjectSomeValuesFrom( )) - -# Class: (negative regulation of phagocytosis) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of phagocytosis.") -AnnotationAssertion( "down regulation of phagocytosis") -AnnotationAssertion( "down-regulation of phagocytosis") -AnnotationAssertion( "downregulation of phagocytosis") -AnnotationAssertion( "inhibition of phagocytosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0050765") -AnnotationAssertion(rdfs:label "negative regulation of phagocytosis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of phagocytosis) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of phagocytosis.") -AnnotationAssertion( "up regulation of phagocytosis") -AnnotationAssertion( "up-regulation of phagocytosis") -AnnotationAssertion( "upregulation of phagocytosis") -AnnotationAssertion( "activation of phagocytosis") -AnnotationAssertion( "stimulation of phagocytosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0050766") -AnnotationAssertion(rdfs:label "positive regulation of phagocytosis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of neurogenesis) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of neurogenesis, the generation of cells in the nervous system.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0050767") -AnnotationAssertion(rdfs:label "regulation of neurogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (negative regulation of neurogenesis) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of neurogenesis, the generation of cells within the nervous system.") -AnnotationAssertion( "down regulation of neurogenesis") -AnnotationAssertion( "down-regulation of neurogenesis") -AnnotationAssertion( "downregulation of neurogenesis") -AnnotationAssertion( "inhibition of neurogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0050768") -AnnotationAssertion(rdfs:label "negative regulation of neurogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of neurogenesis) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of neurogenesis, the generation of cells within the nervous system.") -AnnotationAssertion( "up regulation of neurogenesis") -AnnotationAssertion( "up-regulation of neurogenesis") -AnnotationAssertion( "upregulation of neurogenesis") -AnnotationAssertion( "activation of neurogenesis") -AnnotationAssertion( "stimulation of neurogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0050769") -AnnotationAssertion(rdfs:label "positive regulation of neurogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of axonogenesis) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of axonogenesis, the generation of an axon, the long process of a neuron.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0050770") -AnnotationAssertion(rdfs:label "regulation of axonogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (negative regulation of axonogenesis) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of axonogenesis.") -AnnotationAssertion( "down regulation of axonogenesis") -AnnotationAssertion( "down-regulation of axonogenesis") -AnnotationAssertion( "downregulation of axonogenesis") -AnnotationAssertion( "inhibition of axonogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0050771") -AnnotationAssertion(rdfs:label "negative regulation of axonogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of axonogenesis) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of axonogenesis.") -AnnotationAssertion( "up regulation of axonogenesis") -AnnotationAssertion( "up-regulation of axonogenesis") -AnnotationAssertion( "upregulation of axonogenesis") -AnnotationAssertion( "activation of axonogenesis") -AnnotationAssertion( "stimulation of axonogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0050772") -AnnotationAssertion(rdfs:label "positive regulation of axonogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of dendrite development) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of dendrite development.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0050773") -AnnotationAssertion(rdfs:label "regulation of dendrite development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of dendrite morphogenesis) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of dendrite morphogenesis.") -AnnotationAssertion( "down regulation of dendrite morphogenesis") -AnnotationAssertion( "down-regulation of dendrite morphogenesis") -AnnotationAssertion( "downregulation of dendrite morphogenesis") -AnnotationAssertion( "inhibition of dendrite morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0050774") -AnnotationAssertion(rdfs:label "negative regulation of dendrite morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (positive regulation of dendrite morphogenesis) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of dendrite morphogenesis.") -AnnotationAssertion( "up regulation of dendrite morphogenesis") -AnnotationAssertion( "up-regulation of dendrite morphogenesis") -AnnotationAssertion( "upregulation of dendrite morphogenesis") -AnnotationAssertion( "activation of dendrite morphogenesis") -AnnotationAssertion( "stimulation of dendrite morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0050775") -AnnotationAssertion(rdfs:label "positive regulation of dendrite morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (regulation of immune response) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0050776") -AnnotationAssertion(rdfs:label "regulation of immune response") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of immune response) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.") -AnnotationAssertion( "down regulation of immune response") -AnnotationAssertion( "down-regulation of immune response") -AnnotationAssertion( "downregulation of immune response") -AnnotationAssertion( "inhibition of immune response") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0050777") -AnnotationAssertion(rdfs:label "negative regulation of immune response") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of immune response) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.") -AnnotationAssertion( "up regulation of immune response") -AnnotationAssertion( "up-regulation of immune response") -AnnotationAssertion( "upregulation of immune response") -AnnotationAssertion( "stimulation of immune response") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0050778") -AnnotationAssertion(rdfs:label "positive regulation of immune response") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - # Class: (regulation of biological process) AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.") @@ -91963,29 +26112,14 @@ AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "regulation of biological process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (regulation of catalytic activity) - -AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:ebc") Annotation( "GOC:vw") "Any process that modulates the activity of an enzyme.") -AnnotationAssertion( "GO:0048552") -AnnotationAssertion( "regulation of enzyme activity") -AnnotationAssertion( "regulation of metalloenzyme activity") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0050790") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "regulation of catalytic activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (regulation of developmental process) AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of development, the biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0050793") AnnotationAssertion(rdfs:label "regulation of developmental process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) # Class: (regulation of cellular process) @@ -91997,7 +26131,6 @@ AnnotationAssertion( "GO:0050794") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "regulation of cellular process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (regulation of behavior) @@ -92006,134 +26139,8 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0050795") AnnotationAssertion(rdfs:label "regulation of behavior") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (regulation of insulin secretion) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of the regulated release of insulin.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0050796") -AnnotationAssertion(rdfs:label "regulation of insulin secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (monoatomic ion homeostasis) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process involved in the maintenance of an internal steady state of monoatomic ions within an organism or cell. Monatomic ions (also called simple ions) are ions consisting of exactly one atom.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/24455"^^xsd:anyURI) -AnnotationAssertion( "GO:2000021") -AnnotationAssertion( "ion homeostasis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "electrolyte homeostasis") -AnnotationAssertion( "negative regulation of crystal formation") -AnnotationAssertion( "regulation of ion homeostasis") -AnnotationAssertion( "GO:0050801") -AnnotationAssertion(rdfs:label "monoatomic ion homeostasis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (circadian sleep/wake cycle, sleep) - -AnnotationAssertion(Annotation( "GOC:ai") "The part of the circadian sleep/wake cycle where the organism is asleep.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0050802") -AnnotationAssertion(rdfs:label "circadian sleep/wake cycle, sleep") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of synapse structure or activity) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the physical form or the activity of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell).") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0050803") -AnnotationAssertion(rdfs:label "regulation of synapse structure or activity") -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - -# Class: (modulation of chemical synaptic transmission) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency or amplitude of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse. Amplitude, in this case, refers to the change in postsynaptic membrane potential due to a single instance of synaptic transmission.") -AnnotationAssertion( "modulation of synaptic transmission") -AnnotationAssertion( "regulation of chemical synaptic transmission") -AnnotationAssertion( "regulation of synaptic transmission") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0050804") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "modulation of chemical synaptic transmission") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (negative regulation of synaptic transmission) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse.") -AnnotationAssertion( "down regulation of synaptic transmission") -AnnotationAssertion( "down-regulation of synaptic transmission") -AnnotationAssertion( "downregulation of synaptic transmission") -AnnotationAssertion( "inhibition of synaptic transmission") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0050805") -AnnotationAssertion(rdfs:label "negative regulation of synaptic transmission") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of synaptic transmission) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse.") -AnnotationAssertion( "up regulation of synaptic transmission") -AnnotationAssertion( "up-regulation of synaptic transmission") -AnnotationAssertion( "upregulation of synaptic transmission") -AnnotationAssertion( "activation of synaptic transmission") -AnnotationAssertion( "stimulation of synaptic transmission") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0050806") -AnnotationAssertion(rdfs:label "positive regulation of synaptic transmission") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of synapse organization) - -AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the physical form of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell).") -AnnotationAssertion(Annotation( "GOC:mah") "regulation of synapse organisation") -AnnotationAssertion( "regulation of synapse structure") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:mah") "regulation of synapse organization and biogenesis") -AnnotationAssertion( "GO:0050807") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "regulation of synapse organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (synapse organization) - -AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:pr") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell).") -AnnotationAssertion( "synapse organisation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:aruk") "synapse development") -AnnotationAssertion(Annotation( "GOC:BHF") "synapse morphogenesis") -AnnotationAssertion(Annotation( "GOC:mah") "synapse organization and biogenesis") -AnnotationAssertion( "GO:0050808") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "synapse organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of steroid biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.") -AnnotationAssertion( "regulation of steroid anabolism") -AnnotationAssertion( "regulation of steroid biosynthesis") -AnnotationAssertion( "regulation of steroid formation") -AnnotationAssertion( "regulation of steroid synthesis") -AnnotationAssertion( "regulation of steroidogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0050810") -AnnotationAssertion(rdfs:label "regulation of steroid biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - # Class: (coagulation) AnnotationAssertion(Annotation( "ISBN:0198506732") "The process in which a fluid solution, or part of it, changes into a solid or semisolid mass.") @@ -92144,251 +26151,6 @@ AnnotationAssertion( "coagulation") SubClassOf( ) -# Class: (regulation of coagulation) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of coagulation, the process in which a fluid solution, or part of it, changes into a solid or semisolid mass.") -AnnotationAssertion( "regulation of clotting") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0050818") -AnnotationAssertion(rdfs:label "regulation of coagulation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (negative regulation of coagulation) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of coagulation.") -AnnotationAssertion( "down regulation of coagulation") -AnnotationAssertion( "down-regulation of coagulation") -AnnotationAssertion( "downregulation of coagulation") -AnnotationAssertion( "negative regulation of clotting") -AnnotationAssertion( "inhibition of coagulation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "anticoagulant activity") -AnnotationAssertion( "GO:0050819") -AnnotationAssertion(rdfs:label "negative regulation of coagulation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of coagulation) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of coagulation.") -AnnotationAssertion( "positive regulation of clotting") -AnnotationAssertion( "up regulation of coagulation") -AnnotationAssertion( "up-regulation of coagulation") -AnnotationAssertion( "upregulation of coagulation") -AnnotationAssertion( "activation of coagulation") -AnnotationAssertion( "stimulation of coagulation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0050820") -AnnotationAssertion(rdfs:label "positive regulation of coagulation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (defense response to fungus) - -AnnotationAssertion(Annotation( "GOC:ai") "Reactions triggered in response to the presence of a fungus that act to protect the cell or organism.") -AnnotationAssertion( "GO:0009623") -AnnotationAssertion( "GO:0009817") -AnnotationAssertion( "GO:0042831") -AnnotationAssertion( "defence response to fungi") -AnnotationAssertion( "defence response to fungus") -AnnotationAssertion( "defense response to fungi") -AnnotationAssertion( "defense response to fungus, incompatible interaction") -AnnotationAssertion( "resistance response to pathogenic fungi") -AnnotationAssertion( "resistance response to pathogenic fungus") -AnnotationAssertion( "response to parasitic fungi") -AnnotationAssertion( "response to parasitic fungus") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0050832") -AnnotationAssertion(rdfs:label "defense response to fungus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cell adhesion molecule binding) - -AnnotationAssertion(Annotation( "GOC:ai") "Binding to a cell adhesion molecule.") -AnnotationAssertion( "CAM binding") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "adhesive extracellular matrix constituent") -AnnotationAssertion( "cell adhesion molecule activity") -AnnotationAssertion( "cell adhesion receptor activity") -AnnotationAssertion( "GO:0050839") -AnnotationAssertion(rdfs:label "cell adhesion molecule binding") -SubClassOf( ) - -# Class: (extracellular matrix binding) - -AnnotationAssertion(Annotation( "GOC:ai") "Binding to a component of the extracellular matrix.") -AnnotationAssertion( "extracellular matrix constituent binding") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "adhesive extracellular matrix constituent") -AnnotationAssertion( "GO:0050840") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "extracellular matrix binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of T cell activation) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of T cell activation.") -AnnotationAssertion( "regulation of T lymphocyte activation") -AnnotationAssertion( "regulation of T-cell activation") -AnnotationAssertion( "regulation of T-lymphocyte activation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0050863") -AnnotationAssertion(rdfs:label "regulation of T cell activation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of B cell activation) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of B cell activation.") -AnnotationAssertion( "regulation of B lymphocyte activation") -AnnotationAssertion( "regulation of B-cell activation") -AnnotationAssertion( "regulation of B-lymphocyte activation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0050864") -AnnotationAssertion(rdfs:label "regulation of B cell activation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of cell activation) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of cell activation, the change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0050865") -AnnotationAssertion(rdfs:label "regulation of cell activation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (negative regulation of cell activation) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of cell activation.") -AnnotationAssertion( "down regulation of cell activation") -AnnotationAssertion( "down-regulation of cell activation") -AnnotationAssertion( "downregulation of cell activation") -AnnotationAssertion( "inhibition of cell activation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0050866") -AnnotationAssertion(rdfs:label "negative regulation of cell activation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of cell activation) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of activation.") -AnnotationAssertion( "up regulation of cell activation") -AnnotationAssertion( "up-regulation of cell activation") -AnnotationAssertion( "upregulation of cell activation") -AnnotationAssertion( "activation of cell activation") -AnnotationAssertion( "stimulation of cell activation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0050867") -AnnotationAssertion(rdfs:label "positive regulation of cell activation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of T cell activation) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of T cell activation.") -AnnotationAssertion( "down regulation of T cell activation") -AnnotationAssertion( "down-regulation of T cell activation") -AnnotationAssertion( "downregulation of T cell activation") -AnnotationAssertion( "negative regulation of T lymphocyte activation") -AnnotationAssertion( "negative regulation of T-cell activation") -AnnotationAssertion( "negative regulation of T-lymphocyte activation") -AnnotationAssertion( "inhibition of T cell activation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0050868") -AnnotationAssertion(rdfs:label "negative regulation of T cell activation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of B cell activation) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of B cell activation.") -AnnotationAssertion( "down regulation of B cell activation") -AnnotationAssertion( "down-regulation of B cell activation") -AnnotationAssertion( "downregulation of B cell activation") -AnnotationAssertion( "negative regulation of B lymphocyte activation") -AnnotationAssertion( "negative regulation of B-cell activation") -AnnotationAssertion( "negative regulation of B-lymphocyte activation") -AnnotationAssertion( "inhibition of B cell activation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0050869") -AnnotationAssertion(rdfs:label "negative regulation of B cell activation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of T cell activation) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of T cell activation.") -AnnotationAssertion( "positive regulation of T lymphocyte activation") -AnnotationAssertion( "positive regulation of T-cell activation") -AnnotationAssertion( "positive regulation of T-lymphocyte activation") -AnnotationAssertion( "up regulation of T cell activation") -AnnotationAssertion( "up-regulation of T cell activation") -AnnotationAssertion( "upregulation of T cell activation") -AnnotationAssertion( "activation of T cell activation") -AnnotationAssertion( "stimulation of T cell activation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0050870") -AnnotationAssertion(rdfs:label "positive regulation of T cell activation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of B cell activation) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of B cell activation.") -AnnotationAssertion( "positive regulation of B lymphocyte activation") -AnnotationAssertion( "positive regulation of B-cell activation") -AnnotationAssertion( "positive regulation of B-lymphocyte activation") -AnnotationAssertion( "up regulation of B cell activation") -AnnotationAssertion( "up-regulation of B cell activation") -AnnotationAssertion( "upregulation of B cell activation") -AnnotationAssertion( "activation of B cell activation") -AnnotationAssertion( "stimulation of B cell activation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0050871") -AnnotationAssertion(rdfs:label "positive regulation of B cell activation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (white fat cell differentiation) - -AnnotationAssertion(Annotation( "PMID:12508945") "The process in which a relatively unspecialized cell acquires specialized features of a white adipocyte, an animal connective tissue cell involved in energy storage. White adipocytes have cytoplasmic lipids arranged in a unique vacuole.") -AnnotationAssertion( "white adipocyte cell differentiation") -AnnotationAssertion( "white adipocyte differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0050872") -AnnotationAssertion(rdfs:label "white fat cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (brown fat cell differentiation) - -AnnotationAssertion(Annotation( "PMID:12588810") "The process in which a relatively unspecialized cell acquires specialized features of a brown adipocyte, an animal connective tissue cell involved in adaptive thermogenesis. Brown adipocytes contain multiple small droplets of triglycerides and a high number of mitochondria.") -AnnotationAssertion( ) -AnnotationAssertion( "brown adipocyte cell differentiation") -AnnotationAssertion( "brown adipocyte differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0050873") -AnnotationAssertion(rdfs:label "brown fat cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) -DisjointClasses( ObjectSomeValuesFrom( )) - # Class: (nervous system process) AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:mtg_cardio") "A organ system process carried out by any of the organs or tissues of neurological system.") @@ -92404,7 +26166,6 @@ AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "nervous system process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectAllValuesFrom( )) @@ -92485,7 +26246,6 @@ AnnotationAssertion( "GOC:dph") Annotation( "GOC:tb") "body fluid osmoregulation") AnnotationAssertion( "GO:0050891") AnnotationAssertion(rdfs:label "multicellular organismal-level water homeostasis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) # Class: (response to stimulus) @@ -92505,23 +26265,6 @@ AnnotationAssertion(rdfs:comment "No AnnotationAssertion(rdfs:label "response to stimulus") SubClassOf( ) -# Class: (leukocyte migration) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") Annotation( "PMID:14680625") Annotation( "PMID:14708592") Annotation( "PMID:7507411") Annotation( "PMID:8600538") "The movement of a leukocyte within or between different tissues and organs of the body.") -AnnotationAssertion( "immune cell migration") -AnnotationAssertion( "immune cell trafficking") -AnnotationAssertion( "leucocyte migration") -AnnotationAssertion( "leucocyte trafficking") -AnnotationAssertion( "leukocyte trafficking") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0050900") -AnnotationAssertion(rdfs:label "leukocyte migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - # Class: (neuromuscular process) AnnotationAssertion(Annotation( "GOC:ai") "Any process pertaining to the functions of the nervous and muscular systems of an organism.") @@ -92543,7 +26286,6 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0050906") AnnotationAssertion(rdfs:label "detection of stimulus involved in sensory perception") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) # Class: (detection of chemical stimulus involved in sensory perception) @@ -92558,7 +26300,6 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0050907") AnnotationAssertion(rdfs:label "detection of chemical stimulus involved in sensory perception") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) @@ -92576,23 +26317,9 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0050908") AnnotationAssertion(rdfs:label "detection of light stimulus involved in visual perception") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) -# Class: (sensory perception of taste) - -AnnotationAssertion(Annotation( "GOC:ai") "The series of events required for an organism to receive a gustatory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Gustation involves the direct detection of chemical composition, usually through contact with chemoreceptor cells. This is a neurological process.") -AnnotationAssertion( "Wikipedia:Taste") -AnnotationAssertion( "gustation") -AnnotationAssertion( "sense of taste") -AnnotationAssertion( "taste") -AnnotationAssertion( "taste perception") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0050909") -AnnotationAssertion(rdfs:label "sensory perception of taste") -SubClassOf( ) - # Class: (detection of mechanical stimulus involved in sensory perception of sound) AnnotationAssertion(Annotation( "GOC:ai") "The series of events involved in the perception of sound vibration in which the vibration is received and converted into a molecular signal.") @@ -92609,7 +26336,6 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0050910") AnnotationAssertion(rdfs:label "detection of mechanical stimulus involved in sensory perception of sound") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) @@ -92628,7 +26354,6 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0050911") AnnotationAssertion(rdfs:label "detection of chemical stimulus involved in sensory perception of smell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) # Class: (detection of chemical stimulus involved in sensory perception of taste) @@ -92645,95 +26370,8 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0050912") AnnotationAssertion(rdfs:label "detection of chemical stimulus involved in sensory perception of taste") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (regulation of chemotaxis) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0050920") -AnnotationAssertion(rdfs:label "regulation of chemotaxis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of chemotaxis) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient.") -AnnotationAssertion( "up regulation of chemotaxis") -AnnotationAssertion( "up-regulation of chemotaxis") -AnnotationAssertion( "upregulation of chemotaxis") -AnnotationAssertion( "activation of chemotaxis") -AnnotationAssertion( "stimulation of chemotaxis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0050921") -AnnotationAssertion(rdfs:label "positive regulation of chemotaxis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (negative regulation of chemotaxis) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient.") -AnnotationAssertion( "down regulation of chemotaxis") -AnnotationAssertion( "down-regulation of chemotaxis") -AnnotationAssertion( "downregulation of chemotaxis") -AnnotationAssertion( "inhibition of chemotaxis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0050922") -AnnotationAssertion(rdfs:label "negative regulation of chemotaxis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (pigment cell differentiation) - -AnnotationAssertion(Annotation( "GOC:dgh") "The process in which a relatively unspecialized cell acquires the specialized features of a pigmented cell, such as a melanocyte.") -AnnotationAssertion( "GO:0043357") -AnnotationAssertion( "GO:0043358") -AnnotationAssertion( "chromatophore differentiation") -AnnotationAssertion( "pigmented cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0050931") -AnnotationAssertion(rdfs:comment "Note that the chromatophore mentioned here is distinct from the pigment bearing structure found in certain photosynthetic bacteria and cyanobacteria. It is also different from the plant chromoplast, which is also sometimes called a chromatophore.") -AnnotationAssertion(rdfs:label "pigment cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (regulation of pigment cell differentiation) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of pigmented cell differentiation.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0050932") -AnnotationAssertion(rdfs:label "regulation of pigment cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of pigment cell differentiation) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of pigment cell differentiation.") -AnnotationAssertion( "down regulation of pigment cell differentiation") -AnnotationAssertion( "down-regulation of pigment cell differentiation") -AnnotationAssertion( "downregulation of pigment cell differentiation") -AnnotationAssertion( "inhibition of pigment cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0050941") -AnnotationAssertion(rdfs:label "negative regulation of pigment cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (positive regulation of pigment cell differentiation) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of pigment cell differentiation.") -AnnotationAssertion( "up regulation of pigment cell differentiation") -AnnotationAssertion( "up-regulation of pigment cell differentiation") -AnnotationAssertion( "upregulation of pigment cell differentiation") -AnnotationAssertion( "activation of pigment cell differentiation") -AnnotationAssertion( "stimulation of pigment cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0050942") -AnnotationAssertion(rdfs:label "positive regulation of pigment cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - # Class: (sensory perception of temperature stimulus) AnnotationAssertion(Annotation( "GOC:ai") "The series of events required for an organism to receive a sensory temperature stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.") @@ -92770,17 +26408,6 @@ AnnotationAssertion( "sensory perception of mechanical stimulus") SubClassOf( ) -# Class: (electroception) - -AnnotationAssertion(Annotation( "GOC:ai") Annotation( "PMID:10210663") Annotation( "Wikipedia:Electroreception") "The series of events required for an organism to receive an electrical stimulus, convert it to a molecular signal, and recognize and characterize the signal. Many fish possess an electroception sense; for example, the electric eel uses low voltage pulses of electricity for navigation and prey location.") -AnnotationAssertion( "Wikipedia:Electroreception") -AnnotationAssertion( "electroception sense") -AnnotationAssertion( "electroceptive sense") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0050956") -AnnotationAssertion(rdfs:label "electroception") -SubClassOf( ) - # Class: (equilibrioception) AnnotationAssertion(Annotation( "http://www.medterms.com") "The series of events required for an organism to receive an orientational stimulus, convert it to a molecular signal, and recognize and characterize the signal. Equilibrioception refers to a combination of processes by which an organism can perceive its orientation with respect to gravity. In animals, stimuli come from labyrinth system of the inner ears, monitoring the direction of motion; visual stimuli, with information on orientation and motion; pressure receptors, which tell the organism which body surfaces are in contact with the ground; and proprioceptive cues, which report which parts of the body are in motion.") @@ -92833,7 +26460,6 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0050961") AnnotationAssertion(rdfs:label "detection of temperature stimulus involved in sensory perception") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) @@ -92850,7 +26476,6 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0050962") AnnotationAssertion(rdfs:label "detection of light stimulus involved in sensory perception") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) @@ -92867,7 +26492,6 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0050963") AnnotationAssertion(rdfs:label "detection of electrical stimulus involved in sensory perception") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) @@ -92885,28 +26509,8 @@ AnnotationAssertion( "sensory transduction of electrical stimulus during electroception") AnnotationAssertion( "GO:0050964") AnnotationAssertion(rdfs:label "detection of electrical stimulus involved in electroception") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (detection of temperature stimulus involved in sensory perception of pain) - -AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:dos") "The series of events involved in the perception of pain in which a temperature stimulus is received and converted into a molecular signal.") -AnnotationAssertion( "perception of pain, detection of temperature stimulus") -AnnotationAssertion( "perception of pain, sensory detection of temperature stimulus") -AnnotationAssertion( "perception of pain, sensory transduction of temperature stimulus") -AnnotationAssertion( "sensory detection of temperature stimulus during perception of pain") -AnnotationAssertion( "sensory detection of thermal stimulus during sensory perception of pain") -AnnotationAssertion( "sensory perception of pain, sensory detection of thermal stimulus") -AnnotationAssertion( "sensory perception of pain, sensory transduction of thermal stimulus") -AnnotationAssertion( "sensory transduction of temperature stimulus during perception of pain") -AnnotationAssertion( "sensory transduction of thermal stimulus during sensory perception of pain") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:pr") "thermal nociception") -AnnotationAssertion( "GO:0050965") -AnnotationAssertion(rdfs:label "detection of temperature stimulus involved in sensory perception of pain") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - # Class: (detection of mechanical stimulus involved in sensory perception of pain) AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:dos") "The series of events involved in the perception of pain in which a mechanical stimulus is received and converted into a molecular signal.") @@ -92919,53 +26523,8 @@ AnnotationAssertion( "GOC:pr") "mechanical nociception") AnnotationAssertion( "GO:0050966") AnnotationAssertion(rdfs:label "detection of mechanical stimulus involved in sensory perception of pain") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (detection of electrical stimulus involved in sensory perception of pain) - -AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:dos") Annotation( "GOC:dph") Annotation( "GOC:tb") "The series of events that contribute to the perception of pain in which an electrical stimulus is received and converted into a molecular signal.") -AnnotationAssertion( "perception of pain, detection of electrical stimulus") -AnnotationAssertion( "perception of pain, sensory detection of electrical stimulus") -AnnotationAssertion( "perception of pain, sensory transduction of electrical stimulus") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "detection of electrical stimulus during sensory perception of pain") -AnnotationAssertion( "sensory detection of electrical stimulus during perception of pain") -AnnotationAssertion( "sensory transduction of electrical stimulus during perception of pain") -AnnotationAssertion( "GO:0050967") -AnnotationAssertion(rdfs:label "detection of electrical stimulus involved in sensory perception of pain") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (detection of chemical stimulus involved in sensory perception of pain) - -AnnotationAssertion(Annotation( "GOC:ai") "The series of events involved in the perception of pain in which a chemical stimulus is received and converted into a molecular signal.") -AnnotationAssertion( "perception of pain, detection of chemical stimulus") -AnnotationAssertion( "perception of pain, sensory detection of chemical stimulus") -AnnotationAssertion( "perception of pain, sensory transduction of chemical stimulus") -AnnotationAssertion( "sensory detection of chemical stimulus during perception of pain") -AnnotationAssertion( "sensory transduction of chemical stimulus during perception of pain") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:pr") "chemical nociception") -AnnotationAssertion( "GO:0050968") -AnnotationAssertion(rdfs:label "detection of chemical stimulus involved in sensory perception of pain") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (detection of mechanical stimulus involved in echolocation) - -AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:dos") "The series of events involved in echolocation in which a mechanical stimulus is received and converted into a molecular signal. The stimulus is in the form of a reflected sound wave (an echo), which the organism uses to determine the distance to the object that reflected the sound wave.") -AnnotationAssertion( "echolocation, detection of mechanical stimulus") -AnnotationAssertion( "echolocation, sensory detection of mechanical stimulus") -AnnotationAssertion( "echolocation, sensory transduction of mechanical stimulus") -AnnotationAssertion( "sensory detection of mechanical stimulus during echolocation") -AnnotationAssertion( "sensory transduction of mechanical stimulus during echolocation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0050972") -AnnotationAssertion(rdfs:label "detection of mechanical stimulus involved in echolocation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - # Class: (detection of mechanical stimulus involved in equilibrioception) AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:dos") "The series of events involved in equilibrioception in which a mechanical stimulus is received and converted into a molecular signal. During equilibrioception, mechanical stimuli may be in the form of input from pressure receptors or from the labyrinth system of the inner ears.") @@ -92977,7 +26536,6 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0050973") AnnotationAssertion(rdfs:label "detection of mechanical stimulus involved in equilibrioception") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) # Class: (detection of mechanical stimulus involved in sensory perception) @@ -92992,7 +26550,6 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0050974") AnnotationAssertion(rdfs:label "detection of mechanical stimulus involved in sensory perception") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) @@ -93022,7 +26579,6 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0050976") AnnotationAssertion(rdfs:label "detection of mechanical stimulus involved in sensory perception of touch") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) # Class: (detection of electrical stimulus) @@ -93044,144 +26600,14 @@ SubClassOf( ) SubClassOf( ) -# Class: (regulation of lipid catabolic process) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of lipids.") -AnnotationAssertion( "regulation of lipid breakdown") -AnnotationAssertion( "regulation of lipid catabolism") -AnnotationAssertion( "regulation of lipid degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0050994") -AnnotationAssertion(rdfs:label "regulation of lipid catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of lipid catabolic process) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of lipids.") -AnnotationAssertion( "down regulation of lipid catabolic process") -AnnotationAssertion( "down-regulation of lipid catabolic process") -AnnotationAssertion( "downregulation of lipid catabolic process") -AnnotationAssertion( "negative regulation of lipid breakdown") -AnnotationAssertion( "negative regulation of lipid catabolism") -AnnotationAssertion( "negative regulation of lipid degradation") -AnnotationAssertion( "inhibition of lipid catabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0050995") -AnnotationAssertion(rdfs:label "negative regulation of lipid catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of lipid catabolic process) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of lipids.") -AnnotationAssertion( "positive regulation of lipid breakdown") -AnnotationAssertion( "positive regulation of lipid catabolism") -AnnotationAssertion( "positive regulation of lipid degradation") -AnnotationAssertion( "up regulation of lipid catabolic process") -AnnotationAssertion( "up-regulation of lipid catabolic process") -AnnotationAssertion( "upregulation of lipid catabolic process") -AnnotationAssertion( "activation of lipid catabolic process") -AnnotationAssertion( "stimulation of lipid catabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0050996") -AnnotationAssertion(rdfs:label "positive regulation of lipid catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (quaternary ammonium group binding) - -AnnotationAssertion(Annotation( "GOC:ai") "Binding to a quaternary ammonium group, including glycine betaine, choline, carnitine and proline. A quaternary ammonium group is any compound that can be regarded as derived from ammonium hydroxide or an ammonium salt by replacement of all four hydrogen atoms of the NH4+ ion by organic groups.") -AnnotationAssertion( "quaternary amine binding") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0050997") -AnnotationAssertion(rdfs:label "quaternary ammonium group binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (actin filament bundle assembly) - -AnnotationAssertion(Annotation( "GOC:ai") "The assembly of actin filament bundles; actin filaments are on the same axis but may be oriented with the same or opposite polarities and may be packed with different levels of tightness.") -AnnotationAssertion( "GO:0045011") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "actin bundling activity") -AnnotationAssertion(Annotation( "GOC:mah") "actin cable assembly") -AnnotationAssertion(Annotation( "GOC:mah") "actin cable formation") -AnnotationAssertion( "GO:0051017") -AnnotationAssertion(rdfs:label "actin filament bundle assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (DNA transport) - -AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of RNA, deoxyribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051027") -AnnotationAssertion(rdfs:label "DNA transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (nucleic acid transmembrane transporter activity) - -AnnotationAssertion(Annotation( "GOC:ai") "Enables the transfer of nucleic acids from one side of a membrane to the other. Nucleic acids are single or double-stranded polynucleotides involved in the storage, transmission and transfer of genetic information.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0051032") -AnnotationAssertion(rdfs:label "nucleic acid transmembrane transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (RNA transmembrane transporter activity) - -AnnotationAssertion(Annotation( "GOC:ai") "Enables the transfer of RNA, ribonucleic acid, from one side of a membrane to the other.") -AnnotationAssertion(Annotation(rdfs:label "Exportin complex translocates pre-miRNA to cytosol") "Reactome:R-HSA-203906") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0051033") -AnnotationAssertion(rdfs:label "RNA transmembrane transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (DNA transmembrane transporter activity) - -AnnotationAssertion(Annotation( "GOC:ai") "Enables the transfer of DNA, deoxyribonucleic acid, from one side of a membrane to the other.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0051035") -AnnotationAssertion(rdfs:label "DNA transmembrane transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (regulation of secretion) AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of the controlled release of a substance from a cell or a tissue.") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0051046") AnnotationAssertion(rdfs:label "regulation of secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (positive regulation of secretion) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of the controlled release of a substance from a cell or a tissue.") -AnnotationAssertion( "up regulation of secretion") -AnnotationAssertion( "up-regulation of secretion") -AnnotationAssertion( "upregulation of secretion") -AnnotationAssertion( "activation of secretion") -AnnotationAssertion( "stimulation of secretion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051047") -AnnotationAssertion(rdfs:label "positive regulation of secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of secretion) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a substance from a cell or a tissue.") -AnnotationAssertion( "down regulation of secretion") -AnnotationAssertion( "down-regulation of secretion") -AnnotationAssertion( "downregulation of secretion") -AnnotationAssertion( "inhibition of secretion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051048") -AnnotationAssertion(rdfs:label "negative regulation of secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - # Class: (regulation of transport) AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") @@ -93189,142 +26615,8 @@ AnnotationAssertion( "GO:0051049") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "regulation of transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (positive regulation of transport) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion( "up regulation of transport") -AnnotationAssertion( "up-regulation of transport") -AnnotationAssertion( "upregulation of transport") -AnnotationAssertion( "activation of transport") -AnnotationAssertion( "stimulation of transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051050") -AnnotationAssertion(rdfs:label "positive regulation of transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of transport) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion( "down regulation of transport") -AnnotationAssertion( "down-regulation of transport") -AnnotationAssertion( "downregulation of transport") -AnnotationAssertion( "inhibition of transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051051") -AnnotationAssertion(rdfs:label "negative regulation of transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of DNA metabolic process) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving DNA.") -AnnotationAssertion( "regulation of DNA metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051052") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "regulation of DNA metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of DNA metabolic process) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving DNA.") -AnnotationAssertion( "down regulation of DNA metabolic process") -AnnotationAssertion( "down-regulation of DNA metabolic process") -AnnotationAssertion( "downregulation of DNA metabolic process") -AnnotationAssertion( "negative regulation of DNA metabolism") -AnnotationAssertion( "inhibition of DNA metabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051053") -AnnotationAssertion(rdfs:label "negative regulation of DNA metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of DNA metabolic process) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving DNA.") -AnnotationAssertion( "positive regulation of DNA metabolism") -AnnotationAssertion( "up regulation of DNA metabolic process") -AnnotationAssertion( "up-regulation of DNA metabolic process") -AnnotationAssertion( "upregulation of DNA metabolic process") -AnnotationAssertion( "activation of DNA metabolic process") -AnnotationAssertion( "stimulation of DNA metabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051054") -AnnotationAssertion(rdfs:label "positive regulation of DNA metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of lipid biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids.") -AnnotationAssertion( "down regulation of lipid biosynthetic process") -AnnotationAssertion( "down-regulation of lipid biosynthetic process") -AnnotationAssertion( "downregulation of lipid biosynthetic process") -AnnotationAssertion( "negative regulation of lipid anabolism") -AnnotationAssertion( "negative regulation of lipid biosynthesis") -AnnotationAssertion( "negative regulation of lipid formation") -AnnotationAssertion( "negative regulation of lipid synthesis") -AnnotationAssertion(Annotation( "GOC:sl") "negative regulation of lipogenesis") -AnnotationAssertion( "inhibition of lipid biosynthetic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051055") -AnnotationAssertion(rdfs:label "negative regulation of lipid biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (NF-kappaB binding) - -AnnotationAssertion(Annotation( "GOC:ai") "Binding to NF-kappaB, a transcription factor for eukaryotic RNA polymerase II promoters.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0051059") -AnnotationAssertion(rdfs:label "NF-kappaB binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (meiotic nuclear membrane disassembly) - -AnnotationAssertion(Annotation( "GOC:bf") "The cell cycle process in which the controlled breakdown of the nuclear membranes during meiotic cell division occurs.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "meiotic nuclear envelope breakdown") -AnnotationAssertion( "meiotic nuclear envelope catabolism") -AnnotationAssertion( "meiotic nuclear envelope degradation") -AnnotationAssertion( "meiotic nuclear envelope disassembly") -AnnotationAssertion( "GO:0051078") -AnnotationAssertion(rdfs:label "meiotic nuclear membrane disassembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (meiosis II nuclear membrane disassembly) - -AnnotationAssertion(Annotation( "GOC:bf") "The controlled breakdown of the nuclear membranes during the second division of meiosis.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "meiosis II nuclear envelope breakdown") -AnnotationAssertion( "meiosis II nuclear envelope catabolism") -AnnotationAssertion( "meiosis II nuclear envelope degradation") -AnnotationAssertion( "meiosis II nuclear envelope disassembly") -AnnotationAssertion( "GO:0051080") -AnnotationAssertion(rdfs:label "meiosis II nuclear membrane disassembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (nuclear membrane disassembly) - -AnnotationAssertion(Annotation( "GOC:ai") "The controlled breakdown of the nuclear membranes, for example during cellular division.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "nuclear envelope breakdown") -AnnotationAssertion( "nuclear envelope catabolism") -AnnotationAssertion( "nuclear envelope degradation") -AnnotationAssertion( "nuclear envelope disassembly") -AnnotationAssertion( "GO:0051081") -AnnotationAssertion(rdfs:label "nuclear membrane disassembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (negative regulation of developmental process) AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents or reduces the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).") @@ -93335,369 +26627,9 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0051093") AnnotationAssertion(rdfs:label "negative regulation of developmental process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) -# Class: (positive regulation of developmental process) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).") -AnnotationAssertion( "up regulation of developmental process") -AnnotationAssertion( "up-regulation of developmental process") -AnnotationAssertion( "upregulation of developmental process") -AnnotationAssertion( "activation of developmental process") -AnnotationAssertion( "stimulation of developmental process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051094") -AnnotationAssertion(rdfs:label "positive regulation of developmental process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of binding) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051098") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "regulation of binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of binding) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule.") -AnnotationAssertion( "up regulation of binding") -AnnotationAssertion( "up-regulation of binding") -AnnotationAssertion( "upregulation of binding") -AnnotationAssertion( "activation of binding") -AnnotationAssertion( "stimulation of binding") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051099") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "positive regulation of binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of binding) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops or reduces the rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule.") -AnnotationAssertion( "down regulation of binding") -AnnotationAssertion( "down-regulation of binding") -AnnotationAssertion( "downregulation of binding") -AnnotationAssertion( "inhibition of binding") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051100") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "negative regulation of binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of DNA binding) - -AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid).") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051101") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "regulation of DNA binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (sugar transmembrane transporter activity) - -AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:mtg_transport") Annotation( "ISBN:0815340729") "Enables the transfer of a sugar from one side of a membrane to the other. A sugar is any member of a class of sweet, water-soluble, crystallizable carbohydrates, which are the monosaccharides and smaller oligosaccharides.") -AnnotationAssertion(Annotation(rdfs:label "GLUT7 and GLUT11 transport glucose and fructose") "Reactome:R-HSA-428779") -AnnotationAssertion(Annotation(rdfs:label "SLC45A3 transports Glc from extracellular region to cytosol") "Reactome:R-HSA-8875902") -AnnotationAssertion(Annotation(rdfs:label "SLC50A1 transports Glc from cytosol to extracellular region") "Reactome:R-HSA-8876319") -AnnotationAssertion( "sugar/polyol channel activity") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0051119") -AnnotationAssertion(rdfs:label "sugar transmembrane transporter activity") -SubClassOf( ) - -# Class: (regulation of cellular component organization) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.") -AnnotationAssertion( "regulation of cellular component organisation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:mah") "regulation of cell organisation") -AnnotationAssertion(Annotation( "GOC:mah") "regulation of cell organization") -AnnotationAssertion(Annotation( "GOC:mah") "regulation of cellular component organization and biogenesis") -AnnotationAssertion( "GO:0051128") -AnnotationAssertion(rdfs:label "regulation of cellular component organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of cellular component organization) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.") -AnnotationAssertion( "down regulation of cell organization") -AnnotationAssertion( "down-regulation of cell organization") -AnnotationAssertion( "downregulation of cell organization") -AnnotationAssertion( "inhibition of cell organization") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:mah") "negative regulation of cell organisation") -AnnotationAssertion(Annotation( "GOC:mah") "negative regulation of cellular component organization and biogenesis") -AnnotationAssertion( "GO:0051129") -AnnotationAssertion(rdfs:label "negative regulation of cellular component organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of cellular component organization) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.") -AnnotationAssertion( "positive regulation of cell organisation") -AnnotationAssertion( "up regulation of cell organization") -AnnotationAssertion( "up-regulation of cell organization") -AnnotationAssertion( "upregulation of cell organization") -AnnotationAssertion( "activation of cell organization") -AnnotationAssertion( "stimulation of cell organization") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:mah") "positive regulation of cellular component organization and biogenesis") -AnnotationAssertion( "GO:0051130") -AnnotationAssertion(rdfs:label "positive regulation of cellular component organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (smooth muscle cell differentiation) - -AnnotationAssertion(Annotation( "CL:0000192") Annotation( "GOC:ai") "The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell; smooth muscle lacks transverse striations in its constituent fibers and are almost always involuntary.") -AnnotationAssertion( "nonstriated muscle cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051145") -AnnotationAssertion(rdfs:label "smooth muscle cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (striated muscle cell differentiation) - -AnnotationAssertion(Annotation( "CL:0000737") Annotation( "GOC:ai") "The process in which a relatively unspecialized cell acquires specialized features of a striated muscle cell; striated muscle fibers are divided by transverse bands into striations, and cardiac and voluntary muscle are types of striated muscle.") -AnnotationAssertion( "voluntary muscle cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051146") -AnnotationAssertion(rdfs:label "striated muscle cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of muscle cell differentiation) - -AnnotationAssertion(Annotation( "CL:0000187") Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of muscle cell differentiation.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051147") -AnnotationAssertion(rdfs:label "regulation of muscle cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of muscle cell differentiation) - -AnnotationAssertion(Annotation( "CL:0000187") Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of muscle cell differentiation.") -AnnotationAssertion( "down regulation of muscle cell differentiation") -AnnotationAssertion( "down-regulation of muscle cell differentiation") -AnnotationAssertion( "downregulation of muscle cell differentiation") -AnnotationAssertion( "inhibition of muscle cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051148") -AnnotationAssertion(rdfs:label "negative regulation of muscle cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of muscle cell differentiation) - -AnnotationAssertion(Annotation( "CL:0000187") Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of muscle cell differentiation.") -AnnotationAssertion( "up regulation of muscle cell differentiation") -AnnotationAssertion( "up-regulation of muscle cell differentiation") -AnnotationAssertion( "upregulation of muscle cell differentiation") -AnnotationAssertion( "activation of muscle cell differentiation") -AnnotationAssertion( "stimulation of muscle cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051149") -AnnotationAssertion(rdfs:label "positive regulation of muscle cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of smooth muscle cell differentiation) - -AnnotationAssertion(Annotation( "CL:0000192") Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of smooth muscle cell differentiation.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051150") -AnnotationAssertion(rdfs:label "regulation of smooth muscle cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of smooth muscle cell differentiation) - -AnnotationAssertion(Annotation( "CL:0000192") Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle cell differentiation.") -AnnotationAssertion( "down regulation of smooth muscle cell differentiation") -AnnotationAssertion( "down-regulation of smooth muscle cell differentiation") -AnnotationAssertion( "downregulation of smooth muscle cell differentiation") -AnnotationAssertion( "inhibition of smooth muscle cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051151") -AnnotationAssertion(rdfs:label "negative regulation of smooth muscle cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of smooth muscle cell differentiation) - -AnnotationAssertion(Annotation( "CL:0000192") Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of smooth muscle cell differentiation.") -AnnotationAssertion( "up regulation of smooth muscle cell differentiation") -AnnotationAssertion( "up-regulation of smooth muscle cell differentiation") -AnnotationAssertion( "upregulation of smooth muscle cell differentiation") -AnnotationAssertion( "activation of smooth muscle cell differentiation") -AnnotationAssertion( "stimulation of smooth muscle cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051152") -AnnotationAssertion(rdfs:label "positive regulation of smooth muscle cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of striated muscle cell differentiation) - -AnnotationAssertion(Annotation( "CL:0000737") Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of striated muscle cell differentiation.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051153") -AnnotationAssertion(rdfs:label "regulation of striated muscle cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of striated muscle cell differentiation) - -AnnotationAssertion(Annotation( "CL:0000737") Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle cell differentiation.") -AnnotationAssertion( "down regulation of striated muscle cell differentiation") -AnnotationAssertion( "down-regulation of striated muscle cell differentiation") -AnnotationAssertion( "downregulation of striated muscle cell differentiation") -AnnotationAssertion( "inhibition of striated muscle cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051154") -AnnotationAssertion(rdfs:label "negative regulation of striated muscle cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of striated muscle cell differentiation) - -AnnotationAssertion(Annotation( "CL:0000737") Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of striated muscle cell differentiation.") -AnnotationAssertion( "up regulation of striated muscle cell differentiation") -AnnotationAssertion( "up-regulation of striated muscle cell differentiation") -AnnotationAssertion( "upregulation of striated muscle cell differentiation") -AnnotationAssertion( "activation of striated muscle cell differentiation") -AnnotationAssertion( "stimulation of striated muscle cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051155") -AnnotationAssertion(rdfs:label "positive regulation of striated muscle cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (nuclear export) - -AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of substances out of the nucleus.") -AnnotationAssertion( "export from nucleus") -AnnotationAssertion( "nucleus export") -AnnotationAssertion( "substance nuclear export") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051168") -AnnotationAssertion(rdfs:label "nuclear export") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (nuclear transport) - -AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of substances into, out of, or within the nucleus.") -AnnotationAssertion( "Wikipedia:Nuclear_transport") -AnnotationAssertion( "nucleus transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051169") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "nuclear transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (import into nucleus) - -AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of substances into the nucleus.") -AnnotationAssertion( "jl") -AnnotationAssertion( "2013-12-19T15:26:34Z") -AnnotationAssertion( "GO:1902593") -AnnotationAssertion( "nuclear import") -AnnotationAssertion( "nuclear translocation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051170") -AnnotationAssertion(rdfs:label "import into nucleus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (regulation of nitrogen compound metabolic process) - -AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:tb") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds.") -AnnotationAssertion(Annotation( "GOC:tb") "regulation of nitrogen metabolic process") -AnnotationAssertion( "regulation of nitrogen metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051171") -AnnotationAssertion(rdfs:label "regulation of nitrogen compound metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (negative regulation of nitrogen compound metabolic process) - -AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:tb") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds.") -AnnotationAssertion( "down regulation of nitrogen metabolic process") -AnnotationAssertion( "down-regulation of nitrogen metabolic process") -AnnotationAssertion( "downregulation of nitrogen metabolic process") -AnnotationAssertion(Annotation( "GOC:tb") "negative regulation of nitrogen metabolic process") -AnnotationAssertion( "negative regulation of nitrogen metabolism") -AnnotationAssertion( "inhibition of nitrogen metabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051172") -AnnotationAssertion(rdfs:label "negative regulation of nitrogen compound metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of nitrogen compound metabolic process) - -AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:tb") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds.") -AnnotationAssertion(Annotation( "GOC:tb") "positive regulation of nitrogen metabolic process") -AnnotationAssertion( "positive regulation of nitrogen metabolism") -AnnotationAssertion( "up regulation of nitrogen metabolic process") -AnnotationAssertion( "up-regulation of nitrogen metabolic process") -AnnotationAssertion( "upregulation of nitrogen metabolic process") -AnnotationAssertion( "activation of nitrogen metabolic process") -AnnotationAssertion( "stimulation of nitrogen metabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051173") -AnnotationAssertion(rdfs:label "positive regulation of nitrogen compound metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of phosphorus metabolic process) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus.") -AnnotationAssertion( "regulation of phosphorus metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051174") -AnnotationAssertion(rdfs:label "regulation of phosphorus metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of sulfur metabolic process) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving sulfur or compounds containing sulfur.") -AnnotationAssertion( "down regulation of sulfur metabolic process") -AnnotationAssertion( "down-regulation of sulfur metabolic process") -AnnotationAssertion( "downregulation of sulfur metabolic process") -AnnotationAssertion( "negative regulation of sulfur metabolism") -AnnotationAssertion( "negative regulation of sulphur metabolic process") -AnnotationAssertion( "negative regulation of sulphur metabolism") -AnnotationAssertion( "inhibition of sulfur metabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051175") -AnnotationAssertion(rdfs:label "negative regulation of sulfur metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of sulfur metabolic process) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving sulfur or compounds containing sulfur.") -AnnotationAssertion( "positive regulation of sulfur metabolism") -AnnotationAssertion( "positive regulation of sulphur metabolic process") -AnnotationAssertion( "positive regulation of sulphur metabolism") -AnnotationAssertion( "up regulation of sulfur metabolic process") -AnnotationAssertion( "up-regulation of sulfur metabolic process") -AnnotationAssertion( "upregulation of sulfur metabolic process") -AnnotationAssertion( "activation of sulfur metabolic process") -AnnotationAssertion( "stimulation of sulfur metabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051176") -AnnotationAssertion(rdfs:label "positive regulation of sulfur metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (localization) AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:dos") "Any process in which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported, tethered to or otherwise maintained in a specific location. In the case of substances, localization may also be achieved via selective degradation.") @@ -93718,45 +26650,6 @@ AnnotationAssertion( "localization") SubClassOf( ) -# Class: (sequestering of calcium ion) - -AnnotationAssertion(Annotation( "GOC:ai") "The process of binding or confining calcium ions such that they are separated from other components of a biological system.") -AnnotationAssertion( "calcium ion (Ca2+) retention") -AnnotationAssertion( "calcium ion (Ca2+) sequestering") -AnnotationAssertion( "calcium ion (Ca2+) sequestration") -AnnotationAssertion( "calcium ion (Ca2+) storage") -AnnotationAssertion( "retention of calcium ion (Ca2+)") -AnnotationAssertion( "sequestering of calcium ion (Ca2+)") -AnnotationAssertion( "sequestration of calcium ion (Ca2+)") -AnnotationAssertion( "storage of calcium ion (Ca2+)") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "calcium ion storage activity") -AnnotationAssertion( "negative regulation of calcium ion (Ca2+) transport") -AnnotationAssertion( "GO:0051208") -AnnotationAssertion(rdfs:label "sequestering of calcium ion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (release of sequestered calcium ion into cytosol) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:hjd") Annotation( "GOC:mtg_lung") Annotation( "PMID:1814929") "The process in which calcium ions sequestered in the endoplasmic reticulum, Golgi apparatus or mitochondria are released into the cytosolic compartment.") -AnnotationAssertion( "calcium ion (Ca2+) mobilization") -AnnotationAssertion( "calcium mobilization") -AnnotationAssertion( "cytoplasmic release of sequestered calcium ion (Ca2+)") -AnnotationAssertion( "cytoplasmic release of stored calcium ion (Ca2+)") -AnnotationAssertion( "release of sequestered calcium ion (Ca2+)") -AnnotationAssertion( "release of sequestered calcium ion into cytoplasm") -AnnotationAssertion( "release of stored calcium ion (Ca2+)") -AnnotationAssertion( "release of stored calcium ion (Ca2+) into cytoplasm") -AnnotationAssertion( "cytosolic release of sequestered calcium ion (Ca2+)") -AnnotationAssertion( "cytosolic release of stored calcium ion (Ca2+)") -AnnotationAssertion( "release of stored calcium ion (Ca2+) into cytosol") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051209") -AnnotationAssertion(rdfs:label "release of sequestered calcium ion into cytosol") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ) - # Class: (cartilage development) AnnotationAssertion(Annotation( "GOC:cjm") Annotation( "PMID:23251424") "The process whose specific outcome is the progression of a cartilage element over time, from its formation to the mature structure. Cartilage elements are skeletal elements that consist of connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.") @@ -93770,58 +26663,18 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0051216") AnnotationAssertion(rdfs:label "cartilage development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (positive regulation of protein transport) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion( "up regulation of protein transport") -AnnotationAssertion( "up-regulation of protein transport") -AnnotationAssertion( "upregulation of protein transport") -AnnotationAssertion( "activation of protein transport") -AnnotationAssertion( "stimulation of protein transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051222") -AnnotationAssertion(rdfs:label "positive regulation of protein transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of protein transport) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051223") -AnnotationAssertion(rdfs:label "regulation of protein transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of protein transport) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion( "down regulation of protein transport") -AnnotationAssertion( "down-regulation of protein transport") -AnnotationAssertion( "downregulation of protein transport") -AnnotationAssertion( "inhibition of protein transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051224") -AnnotationAssertion(rdfs:label "negative regulation of protein transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - # Class: (establishment of localization) AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:dos") "Any process that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/24200"^^xsd:anyURI) AnnotationAssertion(Annotation( "GOC:mah") "establishment of localisation") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0051234") +AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( ) @@ -93829,55 +26682,14 @@ AnnotationAssertion( "establishment of localization") SubClassOf( ) -# Class: (maintenance of location) - -AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process in which a cell, substance or cellular entity, such as a protein complex or organelle, is maintained in a location and prevented from moving elsewhere.") -AnnotationAssertion( "maintenance of localization") -AnnotationAssertion( "retention") -AnnotationAssertion( "sequestering") -AnnotationAssertion( "storage") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051235") -AnnotationAssertion(rdfs:label "maintenance of location") -SubClassOf( ) - -# Class: (establishment of RNA localization) - -AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of RNA to a specific location.") -AnnotationAssertion( "RNA positioning") -AnnotationAssertion( "RNA recruitment") -AnnotationAssertion(Annotation( "GOC:mah") "establishment of RNA localisation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051236") -AnnotationAssertion(rdfs:label "establishment of RNA localization") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (regulation of multicellular organismal process) AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs.") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0051239") AnnotationAssertion(rdfs:label "regulation of multicellular organismal process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (positive regulation of multicellular organismal process) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of an organismal process, any of the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs.") -AnnotationAssertion( "up regulation of multicellular organismal process") -AnnotationAssertion( "up-regulation of multicellular organismal process") -AnnotationAssertion( "upregulation of multicellular organismal process") -AnnotationAssertion( "activation of multicellular organismal process") -AnnotationAssertion( "stimulation of multicellular organismal process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051240") -AnnotationAssertion(rdfs:label "positive regulation of multicellular organismal process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (negative regulation of multicellular organismal process) AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of an organismal process, the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs.") @@ -93888,312 +26700,10 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0051241") AnnotationAssertion(rdfs:label "negative regulation of multicellular organismal process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (regulation of protein metabolic process) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a protein.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/23112"^^xsd:anyURI) -AnnotationAssertion( "GO:0032268") -AnnotationAssertion( "regulation of protein metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "regulation of cellular protein metabolic process") -AnnotationAssertion( "regulation of cellular protein metabolism") -AnnotationAssertion( "GO:0051246") -AnnotationAssertion(rdfs:label "regulation of protein metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of protein metabolic process) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/23112"^^xsd:anyURI) -AnnotationAssertion( "GO:0032270") -AnnotationAssertion( "positive regulation of cellular protein metabolic process") -AnnotationAssertion( "positive regulation of cellular protein metabolism") -AnnotationAssertion( "positive regulation of protein metabolism") -AnnotationAssertion( "up regulation of cellular protein metabolic process") -AnnotationAssertion( "up regulation of protein metabolic process") -AnnotationAssertion( "up-regulation of cellular protein metabolic process") -AnnotationAssertion( "up-regulation of protein metabolic process") -AnnotationAssertion( "upregulation of cellular protein metabolic process") -AnnotationAssertion( "upregulation of protein metabolic process") -AnnotationAssertion( "activation of cellular protein metabolic process") -AnnotationAssertion( "activation of protein metabolic process") -AnnotationAssertion( "stimulation of cellular protein metabolic process") -AnnotationAssertion( "stimulation of protein metabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051247") -AnnotationAssertion(rdfs:label "positive regulation of protein metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of protein metabolic process) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of chemical reactions and pathways involving a protein.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/23112"^^xsd:anyURI) -AnnotationAssertion( "GO:0032269") -AnnotationAssertion( "down regulation of cellular protein metabolic process") -AnnotationAssertion( "down regulation of protein metabolic process") -AnnotationAssertion( "down-regulation of cellular protein metabolic process") -AnnotationAssertion( "down-regulation of protein metabolic process") -AnnotationAssertion( "downregulation of cellular protein metabolic process") -AnnotationAssertion( "downregulation of protein metabolic process") -AnnotationAssertion( "negative regulation of cellular protein metabolic process") -AnnotationAssertion( "negative regulation of cellular protein metabolism") -AnnotationAssertion( "negative regulation of protein metabolism") -AnnotationAssertion( "inhibition of cellular protein metabolic process") -AnnotationAssertion( "inhibition of protein metabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051248") -AnnotationAssertion(rdfs:label "negative regulation of protein metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of lymphocyte activation) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of lymphocyte activation.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051249") -AnnotationAssertion(rdfs:label "regulation of lymphocyte activation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (negative regulation of lymphocyte activation) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte activation.") -AnnotationAssertion( "down regulation of lymphocyte activation") -AnnotationAssertion( "down-regulation of lymphocyte activation") -AnnotationAssertion( "downregulation of lymphocyte activation") -AnnotationAssertion( "inhibition of lymphocyte activation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051250") -AnnotationAssertion(rdfs:label "negative regulation of lymphocyte activation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of lymphocyte activation) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of lymphocyte activation.") -AnnotationAssertion( "up regulation of lymphocyte activation") -AnnotationAssertion( "up-regulation of lymphocyte activation") -AnnotationAssertion( "upregulation of lymphocyte activation") -AnnotationAssertion( "activation of lymphocyte activation") -AnnotationAssertion( "stimulation of lymphocyte activation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051251") -AnnotationAssertion(rdfs:label "positive regulation of lymphocyte activation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of RNA metabolic process) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving RNA.") -AnnotationAssertion( "regulation of RNA metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051252") -AnnotationAssertion(rdfs:label "regulation of RNA metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of RNA metabolic process) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving RNA.") -AnnotationAssertion( "down regulation of RNA metabolic process") -AnnotationAssertion( "down-regulation of RNA metabolic process") -AnnotationAssertion( "downregulation of RNA metabolic process") -AnnotationAssertion( "negative regulation of RNA metabolism") -AnnotationAssertion( "inhibition of RNA metabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051253") -AnnotationAssertion(rdfs:label "negative regulation of RNA metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of RNA metabolic process) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving RNA.") -AnnotationAssertion( "positive regulation of RNA metabolism") -AnnotationAssertion( "up regulation of RNA metabolic process") -AnnotationAssertion( "up-regulation of RNA metabolic process") -AnnotationAssertion( "upregulation of RNA metabolic process") -AnnotationAssertion( "activation of RNA metabolic process") -AnnotationAssertion( "stimulation of RNA metabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051254") -AnnotationAssertion(rdfs:label "positive regulation of RNA metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (protein polymerization) - -AnnotationAssertion(Annotation( "GOC:ai") "The process of creating protein polymers, compounds composed of a large number of component monomers; polymeric proteins may be made up of different or identical monomers. Polymerization occurs by the addition of extra monomers to an existing poly- or oligomeric protein.") -AnnotationAssertion( "protein polymer biosynthesis") -AnnotationAssertion( "protein polymer biosynthetic process") -AnnotationAssertion( "protein polymer formation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051258") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "protein polymerization") -SubClassOf( ) - -# Class: (protein depolymerization) - -AnnotationAssertion(Annotation( "GOC:ai") "The process in which protein polymers, compounds composed of a large number of component monomers, are broken down. Depolymerization occurs by the successive removal of monomers from an existing poly- or oligomeric protein.") -AnnotationAssertion( "protein polymer breakdown") -AnnotationAssertion( "protein polymer catabolic process") -AnnotationAssertion( "protein polymer catabolism") -AnnotationAssertion( "protein polymer degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051261") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "protein depolymerization") -SubClassOf( ) - -# Class: (chromosome organization) - -AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:dph") Annotation( "GOC:jl") Annotation( "GOC:mah") "A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of chromosomes, structures composed of a very long molecule of DNA and associated proteins that carries hereditary information. This term covers covalent modifications at the molecular level as well as spatial relationships among the major components of a chromosome.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/22811"^^xsd:anyURI) -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/4585"^^xsd:anyURI) -AnnotationAssertion( "GO:0006323") -AnnotationAssertion( "GO:0007001") -AnnotationAssertion( "GO:0051277") -AnnotationAssertion( "DNA condensation") -AnnotationAssertion( "chromosome organisation") -AnnotationAssertion( "DNA packaging") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:mah") "chromosome organization and biogenesis") -AnnotationAssertion( "maintenance of genome integrity") -AnnotationAssertion( "nuclear genome maintenance") -AnnotationAssertion( "GO:0051276") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "chromosome organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of release of sequestered calcium ion into cytosol) - -AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:tb") "Any process that modulates the frequency, rate or extent of the release into the cytosolic compartment of calcium ions sequestered in the endoplasmic reticulum or mitochondria.") -AnnotationAssertion( "regulation of release of sequestered calcium ion (Ca2+)") -AnnotationAssertion( "regulation of release of stored calcium ion (Ca2+)") -AnnotationAssertion( "regulation of calcium ion (Ca2+) mobilization") -AnnotationAssertion( "regulation of calcium mobilization") -AnnotationAssertion( "regulation of cytoplasmic release of sequestered calcium ion (Ca2+)") -AnnotationAssertion( "regulation of cytoplasmic release of stored calcium ion (Ca2+)") -AnnotationAssertion( "regulation of release of stored calcium ion (Ca2+) into cytoplasm") -AnnotationAssertion( "regulation of release of stored calcium ion (Ca2+) into cytosol") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051279") -AnnotationAssertion(rdfs:label "regulation of release of sequestered calcium ion into cytosol") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of release of sequestered calcium ion into cytosol) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of the release into the cytosolic compartment of calcium ions sequestered in the endoplasmic reticulum or mitochondria.") -AnnotationAssertion( "negative regulation of calcium ion (Ca2+) mobilization") -AnnotationAssertion( "negative regulation of calcium mobilization") -AnnotationAssertion( "negative regulation of cytoplasmic release of sequestered calcium ion (Ca2+)") -AnnotationAssertion( "negative regulation of cytoplasmic release of stored calcium ion (Ca2+)") -AnnotationAssertion( "negative regulation of release of sequestered calcium ion (Ca2+)") -AnnotationAssertion( "negative regulation of release of sequestered calcium ion into cytoplasm") -AnnotationAssertion( "negative regulation of release of stored calcium ion (Ca2+)") -AnnotationAssertion( "negative regulation of release of stored calcium ion (Ca2+) into cytoplasm") -AnnotationAssertion( "down regulation of release of sequestered calcium ion into cytosol") -AnnotationAssertion( "down-regulation of release of sequestered calcium ion into cytosol") -AnnotationAssertion( "downregulation of release of sequestered calcium ion into cytosol") -AnnotationAssertion( "negative regulation of cytosolic release of sequestered calcium ion (Ca2+)") -AnnotationAssertion( "negative regulation of cytosolic release of stored calcium ion (Ca2+)") -AnnotationAssertion( "negative regulation of release of stored calcium ion (Ca2+) into cytosol") -AnnotationAssertion( "inhibition of release of sequestered calcium ion into cytosol") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051280") -AnnotationAssertion(rdfs:label "negative regulation of release of sequestered calcium ion into cytosol") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of release of sequestered calcium ion into cytosol) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of the release into the cytosolic compartment of calcium ions sequestered in the endoplasmic reticulum or mitochondria.") -AnnotationAssertion( "positive regulation of calcium ion (Ca2+) mobilization") -AnnotationAssertion( "positive regulation of calcium mobilization") -AnnotationAssertion( "positive regulation of cytoplasmic release of sequestered calcium ion (Ca2+)") -AnnotationAssertion( "positive regulation of cytoplasmic release of stored calcium ion (Ca2+)") -AnnotationAssertion( "positive regulation of release of sequestered calcium ion (Ca2+)") -AnnotationAssertion( "positive regulation of release of sequestered calcium ion into cytoplasm") -AnnotationAssertion( "positive regulation of release of stored calcium ion (Ca2+)") -AnnotationAssertion( "positive regulation of release of stored calcium ion (Ca2+) into cytoplasm") -AnnotationAssertion( "positive regulation of cytosolic release of sequestered calcium ion (Ca2+)") -AnnotationAssertion( "positive regulation of cytosolic release of stored calcium ion (Ca2+)") -AnnotationAssertion( "positive regulation of release of stored calcium ion (Ca2+) into cytosol") -AnnotationAssertion( "up regulation of release of sequestered calcium ion into cytosol") -AnnotationAssertion( "up-regulation of release of sequestered calcium ion into cytosol") -AnnotationAssertion( "upregulation of release of sequestered calcium ion into cytosol") -AnnotationAssertion( "activation of release of sequestered calcium ion into cytosol") -AnnotationAssertion( "stimulation of release of sequestered calcium ion into cytosol") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051281") -AnnotationAssertion(rdfs:label "positive regulation of release of sequestered calcium ion into cytosol") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of sequestering of calcium ion) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of the binding or confining calcium ions such that they are separated from other components of a biological system.") -AnnotationAssertion( "regulation of calcium ion (Ca2+) retention") -AnnotationAssertion( "regulation of calcium ion (Ca2+) sequestering") -AnnotationAssertion( "regulation of calcium ion (Ca2+) sequestration") -AnnotationAssertion( "regulation of calcium ion (Ca2+) storage") -AnnotationAssertion( "regulation of retention of calcium ion (Ca2+)") -AnnotationAssertion( "regulation of sequestering of calcium ion (Ca2+)") -AnnotationAssertion( "regulation of sequestration of calcium ion (Ca2+)") -AnnotationAssertion( "regulation of storage of calcium ion (Ca2+)") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051282") -AnnotationAssertion(rdfs:label "regulation of sequestering of calcium ion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (negative regulation of sequestering of calcium ion) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of the binding or confining calcium ions such that they are separated from other components of a biological system.") -AnnotationAssertion( "down regulation of sequestering of calcium ion") -AnnotationAssertion( "down-regulation of sequestering of calcium ion") -AnnotationAssertion( "downregulation of sequestering of calcium ion") -AnnotationAssertion( "negative regulation of calcium ion (Ca2+) retention") -AnnotationAssertion( "negative regulation of calcium ion (Ca2+) sequestering") -AnnotationAssertion( "negative regulation of calcium ion (Ca2+) sequestration") -AnnotationAssertion( "negative regulation of calcium ion (Ca2+) storage") -AnnotationAssertion( "negative regulation of retention of calcium ion (Ca2+)") -AnnotationAssertion( "negative regulation of sequestering of calcium ion (Ca2+)") -AnnotationAssertion( "negative regulation of sequestration of calcium ion (Ca2+)") -AnnotationAssertion( "negative regulation of storage of calcium ion (Ca2+)") -AnnotationAssertion( "inhibition of sequestering of calcium ion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051283") -AnnotationAssertion(rdfs:label "negative regulation of sequestering of calcium ion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of sequestering of calcium ion) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of the binding or confining calcium ions such that they are separated from other components of a biological system.") -AnnotationAssertion( "positive regulation of calcium ion (Ca2+) retention") -AnnotationAssertion( "positive regulation of calcium ion (Ca2+) sequestering") -AnnotationAssertion( "positive regulation of calcium ion (Ca2+) sequestration") -AnnotationAssertion( "positive regulation of calcium ion (Ca2+) storage") -AnnotationAssertion( "positive regulation of retention of calcium ion (Ca2+)") -AnnotationAssertion( "positive regulation of sequestering of calcium ion (Ca2+)") -AnnotationAssertion( "positive regulation of sequestration of calcium ion (Ca2+)") -AnnotationAssertion( "positive regulation of storage of calcium ion (Ca2+)") -AnnotationAssertion( "up regulation of sequestering of calcium ion") -AnnotationAssertion( "up-regulation of sequestering of calcium ion") -AnnotationAssertion( "upregulation of sequestering of calcium ion") -AnnotationAssertion( "activation of sequestering of calcium ion") -AnnotationAssertion( "stimulation of sequestering of calcium ion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051284") -AnnotationAssertion(rdfs:label "positive regulation of sequestering of calcium ion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - # Class: (cell division) AnnotationAssertion(Annotation( "GOC:di") Annotation( "GOC:go_curators") Annotation( "GOC:pr") "The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells.") @@ -94207,586 +26717,6 @@ AnnotationAssertion(rdfs:comment "No AnnotationAssertion(rdfs:label "cell division") SubClassOf( ) -# Class: (regulation of cell division) - -AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of the physical partitioning and separation of a cell into daughter cells.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051302") -AnnotationAssertion(rdfs:label "regulation of cell division") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (establishment of chromosome localization) - -AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of a chromosome to a specific location.") -AnnotationAssertion( "chromosome positioning") -AnnotationAssertion(Annotation( "GOC:mah") "establishment of chromosome localisation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051303") -AnnotationAssertion(rdfs:label "establishment of chromosome localization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (meiotic cell cycle) - -AnnotationAssertion(Annotation( "GOC:ai") "Progression through the phases of the meiotic cell cycle, in which canonically a cell replicates to produce four offspring with half the chromosomal content of the progenitor cell via two nuclear divisions.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/24599"^^xsd:anyURI) -AnnotationAssertion( "GO:0007126") -AnnotationAssertion( "Wikipedia:Meiosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "meiosis") -AnnotationAssertion( "GO:0051321") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "Note that this term should not be confused with 'GO:0140013 ; meiotic nuclear division'. 'GO:0051321 ; meiotic cell cycle represents the entire mitotic cell cycle, while 'GO:0140013 meiotic nuclear division' specifically represents the actual nuclear division step of the mitotic cell cycle.") -AnnotationAssertion(rdfs:label "meiotic cell cycle") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - -# Class: (regulation of hydrolase activity) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3.") -AnnotationAssertion( "hydrolase regulator") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051336") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "regulation of hydrolase activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of transferase activity) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2.") -AnnotationAssertion( "transferase regulator") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051338") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "This term is useful for grouping, but is too general for manual annotation. Please use a child term instead.") -AnnotationAssertion(rdfs:label "regulation of transferase activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of hydrolase activity) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds.") -AnnotationAssertion( "hydrolase activator") -AnnotationAssertion( "up regulation of hydrolase activity") -AnnotationAssertion( "up-regulation of hydrolase activity") -AnnotationAssertion( "upregulation of hydrolase activity") -AnnotationAssertion( "activation of hydrolase activity") -AnnotationAssertion( "stimulation of hydrolase activity") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051345") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "positive regulation of hydrolase activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of hydrolase activity) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops or reduces the rate of hydrolase activity, the catalysis of the hydrolysis of various bonds.") -AnnotationAssertion( "down regulation of hydrolase activity") -AnnotationAssertion( "down-regulation of hydrolase activity") -AnnotationAssertion( "downregulation of hydrolase activity") -AnnotationAssertion( "hydrolase inhibitor") -AnnotationAssertion( "inhibition of hydrolase activity") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051346") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "negative regulation of hydrolase activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of transferase activity) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor.") -AnnotationAssertion( "transferase activator") -AnnotationAssertion( "up regulation of transferase activity") -AnnotationAssertion( "up-regulation of transferase activity") -AnnotationAssertion( "upregulation of transferase activity") -AnnotationAssertion( "activation of transferase activity") -AnnotationAssertion( "stimulation of transferase activity") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051347") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "This term is useful for grouping, but is too general for manual annotation. Please use a child term instead.") -AnnotationAssertion(rdfs:label "positive regulation of transferase activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of transferase activity) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops or reduces the rate of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor.") -AnnotationAssertion( "down regulation of transferase activity") -AnnotationAssertion( "down-regulation of transferase activity") -AnnotationAssertion( "downregulation of transferase activity") -AnnotationAssertion( "transferase inhibitor") -AnnotationAssertion( "inhibition of transferase activity") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051348") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "This term is useful for grouping, but is too general for manual annotation. Please use a child term instead.") -AnnotationAssertion(rdfs:label "negative regulation of transferase activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (proprioception involved in equilibrioception) - -AnnotationAssertion(Annotation( "GOC:ai") "The series of events contributing to equilibrioception by which an organism senses the position, location, orientation, and movement of the body and its parts. Proprioception plays an important role in the ability of an organism to perceive its orientation with respect to gravity.") -AnnotationAssertion( "equilibrioception by proprioception") -AnnotationAssertion( "perception of orientation with respect to gravity by proprioception") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "proprioception during equilibrioception") -AnnotationAssertion( "GO:0051355") -AnnotationAssertion(rdfs:label "proprioception involved in equilibrioception") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (visual perception involved in equilibrioception) - -AnnotationAssertion(Annotation( "GOC:ai") "The series of events during equilibrioception required for an organism to receive a visual stimulus, convert it to a molecular signal, and recognize and characterize the signal. Visual input plays an important role in the ability of an organism to perceive its orientation with respect to gravity.") -AnnotationAssertion( "perception of orientation with respect to gravity by visual perception") -AnnotationAssertion( "equilibrioception by visual perception") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "visual perception during equilibrioception") -AnnotationAssertion( "GO:0051356") -AnnotationAssertion(rdfs:label "visual perception involved in equilibrioception") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (serotonin binding) - -AnnotationAssertion(Annotation( "GOC:ai") "Binding to serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties.") -AnnotationAssertion( "5-hydroxytryptamine binding") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0051378") -AnnotationAssertion(rdfs:label "serotonin binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (epinephrine binding) - -AnnotationAssertion(Annotation( "GOC:ai") "Binding to epinephrine, a hormone produced by the medulla of the adrenal glands that increases heart activity, improves the power and prolongs the action of muscles, and increases the rate and depth of breathing. It is synthesized by the methylation of norepinephrine.") -AnnotationAssertion( "adrenaline binding") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0051379") -AnnotationAssertion(rdfs:label "epinephrine binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (norepinephrine binding) - -AnnotationAssertion(Annotation( "GOC:ai") "Binding to norepinephrine, (3,4-dihydroxyphenyl-2-aminoethanol), a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine.") -AnnotationAssertion( "noradrenaline binding") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0051380") -AnnotationAssertion(rdfs:label "norepinephrine binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (histamine binding) - -AnnotationAssertion(Annotation( "GOC:ai") "Binding to histamine, a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0051381") -AnnotationAssertion(rdfs:label "histamine binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (response to glucocorticoid) - -AnnotationAssertion(Annotation( "GOC:ai") Annotation( "PMID:9884123") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucocorticoid stimulus. Glucocorticoids are hormonal C21 corticosteroids synthesized from cholesterol with the ability to bind with the cortisol receptor and trigger similar effects. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects.") -AnnotationAssertion(Annotation( "GOC:dos") "response to glucocorticoid stimulus") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051384") -AnnotationAssertion(rdfs:label "response to glucocorticoid") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (response to mineralocorticoid) - -AnnotationAssertion(Annotation( "GOC:ai") Annotation( "PMID:9884123") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mineralocorticoid stimulus. Mineralocorticoids are hormonal C21 corticosteroids synthesized from cholesterol and characterized by their similarity to aldosterone. Mineralocorticoids act primarily on water and electrolyte balance.") -AnnotationAssertion(Annotation( "GOC:dos") "response to mineralocorticoid stimulus") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051385") -AnnotationAssertion(rdfs:label "response to mineralocorticoid") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (neuron apoptotic process) - -AnnotationAssertion(Annotation( "CL:0000540") Annotation( "GOC:mtg_apoptosis") "Any apoptotic process in a neuron, the basic cellular unit of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system.") -AnnotationAssertion( "apoptosis of neuronal cells") -AnnotationAssertion( "apoptosis of neurons") -AnnotationAssertion( "neuron programmed cell death by apoptosis") -AnnotationAssertion( "neuronal cell apoptosis") -AnnotationAssertion( "neuronal cell programmed cell death by apoptosis") -AnnotationAssertion( "programmed cell death of neuronal cells by apoptosis") -AnnotationAssertion( "programmed cell death of neurons by apoptosis") -AnnotationAssertion( "programmed cell death, neuronal cells") -AnnotationAssertion( "programmed cell death, neurons") -AnnotationAssertion( "neuron apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051402") -AnnotationAssertion(rdfs:label "neuron apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (detoxification of nitrogen compound) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that reduces or removes the toxicity of nitrogenous compounds which are dangerous or toxic. This includes the aerobic conversion of toxic compounds to harmless substances.") -AnnotationAssertion( "detoxification of nitrogenous compound") -AnnotationAssertion( "nitric oxide (NO) detoxification") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051410") -AnnotationAssertion(rdfs:label "detoxification of nitrogen compound") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (regulation of meiotic cell cycle) - -AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the rate or extent of progression through the meiotic cell cycle.") -AnnotationAssertion( "meiotic cell cycle modulation") -AnnotationAssertion( "meiotic cell cycle regulation") -AnnotationAssertion( "modulation of meiotic cell cycle progression") -AnnotationAssertion( "regulation of meiotic cell cycle progression") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "regulation of progression through meiotic cell cycle") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "meiotic cell cycle regulator") -AnnotationAssertion( "GO:0051445") -AnnotationAssertion(rdfs:label "regulation of meiotic cell cycle") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of meiotic cell cycle) - -AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that activates or increases the frequency, rate or extent of progression through the meiotic cell cycle.") -AnnotationAssertion( "positive regulation of meiotic cell cycle progression") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "positive regulation of progression through meiotic cell cycle") -AnnotationAssertion( "up regulation of progression through meiotic cell cycle") -AnnotationAssertion( "up-regulation of progression through meiotic cell cycle") -AnnotationAssertion( "upregulation of progression through meiotic cell cycle") -AnnotationAssertion( "activation of progression through meiotic cell cycle") -AnnotationAssertion( "stimulation of progression through meiotic cell cycle") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051446") -AnnotationAssertion(rdfs:label "positive regulation of meiotic cell cycle") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of meiotic cell cycle) - -AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that stops, prevents or reduces the rate or extent of progression through the meiotic cell cycle.") -AnnotationAssertion( "down regulation of progression through meiotic cell cycle") -AnnotationAssertion( "down-regulation of progression through meiotic cell cycle") -AnnotationAssertion( "downregulation of progression through meiotic cell cycle") -AnnotationAssertion( "negative regulation of meiotic cell cycle progression") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "negative regulation of progression through meiotic cell cycle") -AnnotationAssertion( "inhibition of progression through meiotic cell cycle") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051447") -AnnotationAssertion(rdfs:label "negative regulation of meiotic cell cycle") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (myoblast proliferation) - -AnnotationAssertion(Annotation( "CL:0000056") Annotation( "GOC:ai") Annotation( "GOC:mtg_muscle") "The multiplication or reproduction of myoblasts, resulting in the expansion of a myoblast cell population. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051450") -AnnotationAssertion(rdfs:label "myoblast proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (myoblast migration) - -AnnotationAssertion(Annotation( "CL:0000056") Annotation( "GOC:ai") Annotation( "GOC:mtg_muscle") "The orderly movement of a myoblast from one site to another, often during the development of a multicellular organism. A myoblast is a cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051451") -AnnotationAssertion(rdfs:label "myoblast migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (maintenance of protein location in nucleus) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process in which a protein is maintained in the nucleus and prevented from moving elsewhere. These include sequestration within the nucleus, protein stabilization to prevent transport elsewhere and the active retrieval of proteins that escape the nucleus.") -AnnotationAssertion( "maintenance of nuclear protein localization") -AnnotationAssertion( "maintenance of protein location in cell nucleus") -AnnotationAssertion( "nuclear protein retention") -AnnotationAssertion( "nuclear protein sequestering") -AnnotationAssertion( "nuclear protein sequestration") -AnnotationAssertion( "protein retention in nucleus") -AnnotationAssertion( "protein sequestration in nucleus") -AnnotationAssertion( "protein storage in nucleus") -AnnotationAssertion( "protein-nuclear retention") -AnnotationAssertion( "sequestration of protein in nucleus") -AnnotationAssertion( "storage of protein in nucleus") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "maintenance of protein localization in nucleus") -AnnotationAssertion( "GO:0051457") -AnnotationAssertion(rdfs:label "maintenance of protein location in nucleus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - -# Class: (corticotropin secretion) - -AnnotationAssertion(Annotation( "GOC:cjm") Annotation( "PMID:11027914") "The regulated release of corticotropin by a cell. Corticotropin hormone is a polypeptide hormone synthesized and secreted from corticotropes in the anterior lobe of the pituitary gland in response to corticotropin-releasing hormone (CRH) released by the hypothalamus.") -AnnotationAssertion( "ACTH secretion") -AnnotationAssertion( "adrenocorticotropic hormone secretion") -AnnotationAssertion( "adrenotropic hormone secretion") -AnnotationAssertion( "adrenotropin secretion") -AnnotationAssertion( "corticotropic hormone secretion") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "adrenocorticotropin secretion") -AnnotationAssertion( "GO:0051458") -AnnotationAssertion(rdfs:label "corticotropin secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of corticotropin secretion) - -AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:dph") "Any process that modulates the frequency, rate or extent of the regulated release of corticotropic hormone from a cell.") -AnnotationAssertion( "regulation of ACTH secretion") -AnnotationAssertion(Annotation( "GOC:dph") "regulation of adrenocorticotropic hormone secretion") -AnnotationAssertion( "regulation of adrenocorticotropin secretion") -AnnotationAssertion( "regulation of adrenotropin hormone secretion") -AnnotationAssertion( "regulation of adrenotropin secretion") -AnnotationAssertion( "regulation of corticotropic hormone secretion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051459") -AnnotationAssertion(rdfs:label "regulation of corticotropin secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (negative regulation of corticotropin secretion) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of corticotropic hormone from a cell.") -AnnotationAssertion( "down regulation of adrenocorticotropin secretion") -AnnotationAssertion( "down-regulation of adrenocorticotropin secretion") -AnnotationAssertion( "downregulation of adrenocorticotropin secretion") -AnnotationAssertion( "negative regulation of ACTH secretion") -AnnotationAssertion( "negative regulation of adrenocorticotropic hormone secretion") -AnnotationAssertion( "negative regulation of adrenocorticotropin secretion") -AnnotationAssertion( "negative regulation of adrenotropic hormone secretion") -AnnotationAssertion( "negative regulation of adrenotropin secretion") -AnnotationAssertion( "negative regulation of corticotropic hormone secretion") -AnnotationAssertion( "inhibition of adrenocorticotropin secretion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051460") -AnnotationAssertion(rdfs:label "negative regulation of corticotropin secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of corticotropin secretion) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of the regulated release of corticotropin hormone from a cell.") -AnnotationAssertion( "positive regulation of ACTH secretion") -AnnotationAssertion( "positive regulation of adrenocorticotropic hormone secretion") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "positive regulation of adrenocorticotropin secretion") -AnnotationAssertion( "positive regulation of adrenotropic hormone secretion") -AnnotationAssertion( "positive regulation of adrenotropin secretion") -AnnotationAssertion( "positive regulation of corticotropic hormone secretion") -AnnotationAssertion( "up regulation of adrenocorticotropin secretion") -AnnotationAssertion( "up-regulation of adrenocorticotropin secretion") -AnnotationAssertion( "upregulation of adrenocorticotropin secretion") -AnnotationAssertion( "activation of adrenocorticotropin secretion") -AnnotationAssertion( "stimulation of adrenocorticotropin secretion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051461") -AnnotationAssertion(rdfs:label "positive regulation of corticotropin secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (vesicle fusion with vacuole) - -AnnotationAssertion(Annotation( "GOC:ai") "The joining of the lipid bilayer membrane around a vesicle with the lipid bilayer membrane around the vacuole.") -AnnotationAssertion( "GO:0042146") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "heterotypic vacuole fusion (non-autophagic)") -AnnotationAssertion( "heterotypic vacuole fusion, non-autophagic") -AnnotationAssertion( "GO:0051469") -AnnotationAssertion(rdfs:label "vesicle fusion with vacuole") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of cytoskeleton organization) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures.") -AnnotationAssertion(Annotation( "GOC:mah") "regulation of cytoskeleton organisation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:mah") "regulation of cytoskeleton organization and biogenesis") -AnnotationAssertion( "GO:0051493") -AnnotationAssertion(rdfs:label "regulation of cytoskeleton organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of cytoskeleton organization) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures.") -AnnotationAssertion( "down regulation of cytoskeleton organization") -AnnotationAssertion( "down-regulation of cytoskeleton organization") -AnnotationAssertion( "downregulation of cytoskeleton organization") -AnnotationAssertion(Annotation( "GOC:mah") "negative regulation of cytoskeleton organisation") -AnnotationAssertion( "inhibition of cytoskeleton organization") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:mah") "negative regulation of cytoskeleton organization and biogenesis") -AnnotationAssertion( "GO:0051494") -AnnotationAssertion(rdfs:label "negative regulation of cytoskeleton organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of cytoskeleton organization) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures.") -AnnotationAssertion(Annotation( "GOC:mah") "positive regulation of cytoskeleton organisation") -AnnotationAssertion( "up regulation of cytoskeleton organization") -AnnotationAssertion( "up-regulation of cytoskeleton organization") -AnnotationAssertion( "upregulation of cytoskeleton organization") -AnnotationAssertion( "activation of cytoskeleton organization") -AnnotationAssertion( "stimulation of cytoskeleton organization") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:mah") "positive regulation of cytoskeleton organization and biogenesis") -AnnotationAssertion( "GO:0051495") -AnnotationAssertion(rdfs:label "positive regulation of cytoskeleton organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (adenine nucleotide transport) - -AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of adenine nucleotides, ATP, ADP, and/or AMP, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051503") -AnnotationAssertion(rdfs:label "adenine nucleotide transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (keratinocyte migration) - -AnnotationAssertion(Annotation( "ISBN:0721662544") "The directed movement of a keratinocyte, epidermal cells which synthesize keratin, from one site to another.") -AnnotationAssertion( ) -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051546") -AnnotationAssertion(rdfs:label "keratinocyte migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) -DisjointClasses( ObjectSomeValuesFrom( )) - -# Class: (regulation of keratinocyte migration) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of keratinocyte migration.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051547") -AnnotationAssertion(rdfs:label "regulation of keratinocyte migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of keratinocyte migration) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of keratinocyte migration.") -AnnotationAssertion( "down regulation of keratinocyte migration") -AnnotationAssertion( "down-regulation of keratinocyte migration") -AnnotationAssertion( "downregulation of keratinocyte migration") -AnnotationAssertion( "inhibition of keratinocyte migration") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051548") -AnnotationAssertion(rdfs:label "negative regulation of keratinocyte migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of keratinocyte migration) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of keratinocyte migration.") -AnnotationAssertion( "up regulation of keratinocyte migration") -AnnotationAssertion( "up-regulation of keratinocyte migration") -AnnotationAssertion( "upregulation of keratinocyte migration") -AnnotationAssertion( "activation of keratinocyte migration") -AnnotationAssertion( "stimulation of keratinocyte migration") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051549") -AnnotationAssertion(rdfs:label "positive regulation of keratinocyte migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of neurotransmitter uptake) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of the directed movement of a neurotransmitter into a neuron or glial cell.") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "regulation of neurotransmitter import") -AnnotationAssertion( "regulation of neurotransmitter reuptake") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051580") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "regulation of neurotransmitter uptake") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of neurotransmitter uptake) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a neurotransmitter into a neuron or glial cell.") -AnnotationAssertion( "down regulation of neurotransmitter uptake") -AnnotationAssertion( "down-regulation of neurotransmitter uptake") -AnnotationAssertion( "downregulation of neurotransmitter uptake") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "negative regulation of neurotransmitter import") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051581") -AnnotationAssertion(rdfs:label "negative regulation of neurotransmitter uptake") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of neurotransmitter uptake) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of the directed movement of a neurotransmitter into a neuron or glial cell.") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "positive regulation of neurotransmitter import") -AnnotationAssertion( "up regulation of neurotransmitter uptake") -AnnotationAssertion( "up-regulation of neurotransmitter uptake") -AnnotationAssertion( "upregulation of neurotransmitter uptake") -AnnotationAssertion( "activation of neurotransmitter uptake") -AnnotationAssertion( "stimulation of neurotransmitter uptake") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051582") -AnnotationAssertion(rdfs:label "positive regulation of neurotransmitter uptake") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of neurotransmitter transport) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of the directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051588") -AnnotationAssertion(rdfs:label "regulation of neurotransmitter transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of neurotransmitter transport) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion( "down regulation of neurotransmitter transport") -AnnotationAssertion( "down-regulation of neurotransmitter transport") -AnnotationAssertion( "downregulation of neurotransmitter transport") -AnnotationAssertion( "inhibition of neurotransmitter transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051589") -AnnotationAssertion(rdfs:label "negative regulation of neurotransmitter transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of neurotransmitter transport) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of the directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion( "up regulation of neurotransmitter transport") -AnnotationAssertion( "up-regulation of neurotransmitter transport") -AnnotationAssertion( "upregulation of neurotransmitter transport") -AnnotationAssertion( "activation of neurotransmitter transport") -AnnotationAssertion( "stimulation of neurotransmitter transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051590") -AnnotationAssertion(rdfs:label "positive regulation of neurotransmitter transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (response to calcium ion) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus.") -AnnotationAssertion( "response to Ca2+ ion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051592") -AnnotationAssertion(rdfs:label "response to calcium ion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (response to electrical stimulus) AnnotationAssertion(Annotation( "GOC:ai") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electrical stimulus.") @@ -94796,23 +26726,6 @@ AnnotationAssertion( "response to electrical stimulus") SubClassOf( ) -# Class: (proteolysis involved in protein catabolic process) - -AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:dph") Annotation( "GOC:tb") "The hydrolysis of a peptide bond or bonds within a protein as part of the chemical reactions and pathways resulting in the breakdown of a protein by individual cells.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/23112"^^xsd:anyURI) -AnnotationAssertion( "peptidolysis involved in cellular protein catabolic process") -AnnotationAssertion( "peptidolysis involved in cellular protein catabolism") -AnnotationAssertion( "proteolysis involved in cellular protein catabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "peptidolysis during cellular protein catabolic process") -AnnotationAssertion( "peptidolysis during cellular protein catabolism") -AnnotationAssertion( "proteolysis during cellular protein catabolic process") -AnnotationAssertion( "proteolysis during cellular protein catabolism") -AnnotationAssertion( "GO:0051603") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "proteolysis involved in protein catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (protein maturation) AnnotationAssertion(Annotation( "GOC:ai") "Any process leading to the attainment of the full functional capacity of a protein.") @@ -94841,225 +26754,6 @@ AnnotationAssertion( "detection of stimulus") SubClassOf( ) -# Class: (histamine transport) - -AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of histamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Histamine is a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051608") -AnnotationAssertion(rdfs:label "histamine transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (histamine uptake) - -AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of histamine into a cell, typically presynaptic neurons or glial cells. Histamine is a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans.") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "histamine import") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051615") -AnnotationAssertion(rdfs:label "histamine uptake") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of histamine uptake) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of the directed movement of the neurotransmitter histamine into a cell.") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "regulation of histamine import") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051616") -AnnotationAssertion(rdfs:label "regulation of histamine uptake") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of histamine uptake) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of histamine into a cell.") -AnnotationAssertion( "down regulation of histamine uptake") -AnnotationAssertion( "down-regulation of histamine uptake") -AnnotationAssertion( "downregulation of histamine uptake") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "negative regulation of histamine import") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051617") -AnnotationAssertion(rdfs:label "negative regulation of histamine uptake") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of histamine uptake) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of the directed movement of histamine into a cell.") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "positive regulation of histamine import") -AnnotationAssertion( "up regulation of histamine uptake") -AnnotationAssertion( "up-regulation of histamine uptake") -AnnotationAssertion( "upregulation of histamine uptake") -AnnotationAssertion( "activation of histamine uptake") -AnnotationAssertion( "stimulation of histamine uptake") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051618") -AnnotationAssertion(rdfs:label "positive regulation of histamine uptake") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (norepinephrine uptake) - -AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of norepinephrine into a cell, typically presynaptic neurons or glial cells. Norepinephrine (3,4-dihydroxyphenyl-2-aminoethanol) is a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine.") -AnnotationAssertion( "levarterenol reuptake") -AnnotationAssertion( "levarterenol uptake") -AnnotationAssertion( "noradrenaline reuptake") -AnnotationAssertion( "noradrenaline uptake") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "norepinephrine import") -AnnotationAssertion( "norepinephrine reuptake") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051620") -AnnotationAssertion(rdfs:label "norepinephrine uptake") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (regulation of norepinephrine uptake) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of the directed movement of the neurotransmitter norepinephrine into a cell.") -AnnotationAssertion( "regulation of levarterenol uptake") -AnnotationAssertion( "regulation of noradrenaline uptake") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "regulation of norepinephrine import") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051621") -AnnotationAssertion(rdfs:label "regulation of norepinephrine uptake") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of norepinephrine uptake) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of norepinephrine into a cell.") -AnnotationAssertion( "down regulation of norepinephrine uptake") -AnnotationAssertion( "down-regulation of norepinephrine uptake") -AnnotationAssertion( "downregulation of norepinephrine uptake") -AnnotationAssertion( "negative regulation of levarterenol uptake") -AnnotationAssertion( "negative regulation of noradrenaline uptake") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "negative regulation of norepinephrine import") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051622") -AnnotationAssertion(rdfs:label "negative regulation of norepinephrine uptake") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of norepinephrine uptake) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of the directed movement of norepinephrine into a cell.") -AnnotationAssertion( "positive regulation of levarterenol uptake") -AnnotationAssertion( "positive regulation of noradrenaline uptake") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "positive regulation of norepinephrine import") -AnnotationAssertion( "up regulation of norepinephrine uptake") -AnnotationAssertion( "up-regulation of norepinephrine uptake") -AnnotationAssertion( "upregulation of norepinephrine uptake") -AnnotationAssertion( "activation of norepinephrine uptake") -AnnotationAssertion( "stimulation of norepinephrine uptake") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051623") -AnnotationAssertion(rdfs:label "positive regulation of norepinephrine uptake") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (epinephrine uptake) - -AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of epinephrine into a cell, typically presynaptic neurons or glial cells. Epinephrine is a hormone produced by the medulla of the adrenal glands that increases heart activity, improves the power and prolongs the action of muscles, and increases the rate and depth of breathing. It is synthesized by the methylation of norepinephrine.") -AnnotationAssertion( "adrenaline reuptake") -AnnotationAssertion( "adrenaline uptake") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "epinephrine import") -AnnotationAssertion( "epinephrine reuptake") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051625") -AnnotationAssertion(rdfs:label "epinephrine uptake") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (regulation of epinephrine uptake) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of the directed movement of the neurotransmitter epinephrine into a cell.") -AnnotationAssertion( "regulation of adrenaline uptake") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "regulation of epinephrine import") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051626") -AnnotationAssertion(rdfs:label "regulation of epinephrine uptake") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of epinephrine uptake) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of epinephrine into a cell.") -AnnotationAssertion( "down regulation of epinephrine uptake") -AnnotationAssertion( "down-regulation of epinephrine uptake") -AnnotationAssertion( "downregulation of epinephrine uptake") -AnnotationAssertion( "negative regulation of adrenaline uptake") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "negative regulation of epinephrine import") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051627") -AnnotationAssertion(rdfs:label "negative regulation of epinephrine uptake") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of epinephrine uptake) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of the directed movement of epinephrine into a cell.") -AnnotationAssertion( "positive regulation of adrenaline uptake") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "positive regulation of epinephrine import") -AnnotationAssertion( "up regulation of epinephrine uptake") -AnnotationAssertion( "up-regulation of epinephrine uptake") -AnnotationAssertion( "upregulation of epinephrine uptake") -AnnotationAssertion( "activation of epinephrine uptake") -AnnotationAssertion( "stimulation of epinephrine uptake") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051628") -AnnotationAssertion(rdfs:label "positive regulation of epinephrine uptake") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (acetylcholine uptake) - -AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of acetylcholine into a cell, typically presynaptic neurons or glial cells. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues.") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "acetylcholine import") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051630") -AnnotationAssertion(rdfs:label "acetylcholine uptake") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (regulation of acetylcholine uptake) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of the directed movement of the neurotransmitter acetylcholine into a cell.") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "regulation of acetylcholine import") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051631") -AnnotationAssertion(rdfs:label "regulation of acetylcholine uptake") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (negative regulation of acetylcholine uptake) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of acetylcholine into a cell.") -AnnotationAssertion( "down regulation of acetylcholine uptake") -AnnotationAssertion( "down-regulation of acetylcholine uptake") -AnnotationAssertion( "downregulation of acetylcholine uptake") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "negative regulation of acetylcholine import") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051632") -AnnotationAssertion(rdfs:label "negative regulation of acetylcholine uptake") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (positive regulation of acetylcholine uptake) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of the directed movement of acetylcholine into a cell.") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "positive regulation of acetylcholine import") -AnnotationAssertion( "up regulation of acetylcholine uptake") -AnnotationAssertion( "up-regulation of acetylcholine uptake") -AnnotationAssertion( "upregulation of acetylcholine uptake") -AnnotationAssertion( "activation of acetylcholine uptake") -AnnotationAssertion( "stimulation of acetylcholine uptake") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051633") -AnnotationAssertion(rdfs:label "positive regulation of acetylcholine uptake") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (organelle localization) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process in which an organelle is transported to, and/or maintained in, a specific location.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/19809"^^xsd:anyURI) -AnnotationAssertion( "establishment and maintenance of organelle localization") -AnnotationAssertion(Annotation( "GOC:mah") "organelle localisation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051640") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "organelle localization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - # Class: (cellular localization) AnnotationAssertion(Annotation( "GOC:tb") Annotation( "GOC:vw") "A cellular localization process whereby a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a cell including the localization of substances or cellular entities to the cell membrane.") @@ -95080,195 +26774,6 @@ AnnotationAssertion(rdfs:label "cell SubClassOf( ) SubClassOf( ) -# Class: (Golgi localization) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process in which the Golgi is transported to, and/or maintained in, a specific location within the cell.") -AnnotationAssertion( "Golgi apparatus localization") -AnnotationAssertion( "Golgi body localization") -AnnotationAssertion(Annotation( "GOC:mah") "Golgi localisation") -AnnotationAssertion( "establishment and maintenance of Golgi localization") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051645") -AnnotationAssertion(rdfs:label "Golgi localization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (nucleus localization) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process in which the nucleus is transported to, and/or maintained in, a specific location within the cell.") -AnnotationAssertion( "cell nucleus localization") -AnnotationAssertion( "establishment and maintenance of nucleus localization") -AnnotationAssertion( "localization of nucleus") -AnnotationAssertion(Annotation( "GOC:mah") "nucleus localisation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051647") -AnnotationAssertion(rdfs:label "nucleus localization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (vesicle localization) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process in which a vesicle or vesicles are transported to, and/or maintained in, a specific location.") -AnnotationAssertion( "cytoplasmic vesicle localization") -AnnotationAssertion( "establishment and maintenance of vesicle localization") -AnnotationAssertion(Annotation( "GOC:mah") "vesicle localisation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051648") -AnnotationAssertion(rdfs:label "vesicle localization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (establishment of localization in cell) - -AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:dos") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process, occuring in a cell, that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation.") -AnnotationAssertion(Annotation( "GOC:mah") "establishment of localisation in cell") -AnnotationAssertion( "establishment of intracellular localization") -AnnotationAssertion( "establishment of localization within cell") -AnnotationAssertion( "positioning within cell") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "establishment of cellular localization") -AnnotationAssertion( "GO:0051649") -AnnotationAssertion(rdfs:label "establishment of localization in cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - -# Class: (establishment of vesicle localization) - -AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of a vesicle to a specific location.") -AnnotationAssertion(Annotation( "GOC:mah") "establishment of vesicle localisation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051650") -AnnotationAssertion(rdfs:label "establishment of vesicle localization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (maintenance of location in cell) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process in which a substance or cellular entity, such as a protein complex or organelle, is maintained in a specific location within, or in the membrane of, a cell, and is prevented from moving elsewhere.") -AnnotationAssertion( "cellular retention") -AnnotationAssertion( "cellular sequestering") -AnnotationAssertion( "cellular storage") -AnnotationAssertion( "intracellular retention") -AnnotationAssertion( "intracellular sequestering") -AnnotationAssertion( "intracellular storage") -AnnotationAssertion( "maintenance of intracellular localization") -AnnotationAssertion( "maintenance of localization within cell") -AnnotationAssertion( "retention within cell") -AnnotationAssertion( "sequestering within cell") -AnnotationAssertion( "storage within cell") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "maintenance of cellular localization") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "maintenance of localization in cell") -AnnotationAssertion( "GO:0051651") -AnnotationAssertion(rdfs:label "maintenance of location in cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (maintenance of chromosome location) - -AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process in which a chromosome is maintained in a specific location within a cell and prevented from moving elsewhere.") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "maintenance of chromosome localization") -AnnotationAssertion( "GO:0051652") -AnnotationAssertion(rdfs:label "maintenance of chromosome location") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (maintenance of vesicle location) - -AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process in which a vesicle is maintained in a specific location within a cell and prevented from moving elsewhere.") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "maintenance of vesicle localization") -AnnotationAssertion( "GO:0051655") -AnnotationAssertion(rdfs:label "maintenance of vesicle location") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (establishment of organelle localization) - -AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of an organelle to a specific location.") -AnnotationAssertion(Annotation( "GOC:mah") "establishment of organelle localisation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051656") -AnnotationAssertion(rdfs:label "establishment of organelle localization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (maintenance of organelle location) - -AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process in which an organelle is maintained in a specific location within a cell and prevented from moving elsewhere.") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "maintenance of organelle localization") -AnnotationAssertion( "GO:0051657") -AnnotationAssertion(rdfs:label "maintenance of organelle location") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (maintenance of nucleus location) - -AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process in which the nucleus is maintained in a specific location within a cell and prevented from moving elsewhere.") -AnnotationAssertion( "maintenance of cell nucleus location") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "maintenance of nucleus localization") -AnnotationAssertion( "GO:0051658") -AnnotationAssertion(rdfs:label "maintenance of nucleus location") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (localization within membrane) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process in which a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a membrane.") -AnnotationAssertion( "establishment and maintenance of localization in membrane") -AnnotationAssertion( "establishment and maintenance of position in membrane") -AnnotationAssertion(Annotation( "GOC:mah") "localisation within membrane") -AnnotationAssertion( "localization to membrane") -AnnotationAssertion( "positioning within membrane") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051668") -AnnotationAssertion(rdfs:label "localization within membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (localization of cell) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process in which a cell is transported to, and/or maintained in, a specific location.") -AnnotationAssertion( "cell localization") -AnnotationAssertion( "establishment and maintenance of cell localization") -AnnotationAssertion( "establishment and maintenance of localization of cell") -AnnotationAssertion(Annotation( "GOC:mah") "localisation of cell") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051674") -AnnotationAssertion(rdfs:label "localization of cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (establishment of Golgi localization) - -AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of the Golgi to a specific location.") -AnnotationAssertion( "establishment of Golgi apparatus localization") -AnnotationAssertion( "establishment of Golgi body localization") -AnnotationAssertion(Annotation( "GOC:mah") "establishment of Golgi localisation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051683") -AnnotationAssertion(rdfs:label "establishment of Golgi localization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (maintenance of Golgi location) - -AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process in which the Golgi is maintained in a specific location within a cell and prevented from moving elsewhere.") -AnnotationAssertion( "maintenance of Golgi apparatus localization") -AnnotationAssertion( "maintenance of Golgi body localization") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "maintenance of Golgi localization") -AnnotationAssertion( "GO:0051684") -AnnotationAssertion(rdfs:label "maintenance of Golgi location") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - # Class: (response to other organism) AnnotationAssertion(Annotation( "GOC:ai") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from another living organism.") @@ -95277,7 +26782,6 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0051707") AnnotationAssertion(rdfs:label "response to other organism") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) @@ -95292,617 +26796,6 @@ AnnotationAssertion(rdfs:label "cell SubClassOf( ) SubClassOf( ) -# Class: (regulation of cell cycle) - -AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the rate or extent of progression through the cell cycle.") -AnnotationAssertion( "GO:0000074") -AnnotationAssertion( "GO:0007050") -AnnotationAssertion( "GO:0071156") -AnnotationAssertion( "GO:0071157") -AnnotationAssertion( "GO:0071158") -AnnotationAssertion( "GO:0071850") -AnnotationAssertion( "cell cycle modulation") -AnnotationAssertion( "cell cycle regulation") -AnnotationAssertion( "control of cell cycle progression") -AnnotationAssertion( "modulation of cell cycle progression") -AnnotationAssertion( "regulation of cell cycle progression") -AnnotationAssertion( "regulation of progression through cell cycle") -AnnotationAssertion(Annotation( "GOC:mah") "arrest of mitotic cell cycle progression") -AnnotationAssertion( "cell cycle arrest") -AnnotationAssertion( "mitotic cell cycle arrest") -AnnotationAssertion( "negative regulation of cell cycle arrest") -AnnotationAssertion( "positive regulation of cell cycle arrest") -AnnotationAssertion( "regulation of cell cycle arrest") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "cell cycle regulator") -AnnotationAssertion( "tumor suppressor") -AnnotationAssertion( "GO:0051726") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "regulation of cell cycle") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (xanthophyll binding) - -AnnotationAssertion(Annotation( "ISBN:0122146743") "Binding to xanthophylls, any of several neutral yellow to orange carotenoid pigments containing oxygen.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0051738") -AnnotationAssertion(rdfs:label "xanthophyll binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (sesquiterpene metabolic process) - -AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways involving sesquiterpenes, any of a class of terpenes of the formula C15H24 or a derivative of such a terpene.") -AnnotationAssertion( "sesquiterpene metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051761") -AnnotationAssertion(rdfs:label "sesquiterpene metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (sesquiterpene biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways resulting in the formation of sesquiterpenes, any of a class of terpenes of the formula C15H24 or a derivative of such a terpene.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051762") -AnnotationAssertion(rdfs:label "sesquiterpene biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (sesquiterpene catabolic process) - -AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways resulting in the breakdown of sesquiterpenes, any of a class of terpenes of the formula C15H24 or a derivative of such a terpene.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051763") -AnnotationAssertion(rdfs:label "sesquiterpene catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of cell division) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of cell division.") -AnnotationAssertion( "up regulation of cell division") -AnnotationAssertion( "up-regulation of cell division") -AnnotationAssertion( "upregulation of cell division") -AnnotationAssertion( "activation of cell division") -AnnotationAssertion( "stimulation of cell division") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051781") -AnnotationAssertion(rdfs:label "positive regulation of cell division") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of cell division) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of cell division.") -AnnotationAssertion( "down regulation of cell division") -AnnotationAssertion( "down-regulation of cell division") -AnnotationAssertion( "downregulation of cell division") -AnnotationAssertion( "inhibition of cell division") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051782") -AnnotationAssertion(rdfs:label "negative regulation of cell division") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of nuclear division) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051783") -AnnotationAssertion(rdfs:label "regulation of nuclear division") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (negative regulation of nuclear division) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information.") -AnnotationAssertion( "down regulation of nuclear division") -AnnotationAssertion( "down-regulation of nuclear division") -AnnotationAssertion( "downregulation of nuclear division") -AnnotationAssertion( "inhibition of nuclear division") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051784") -AnnotationAssertion(rdfs:label "negative regulation of nuclear division") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of nuclear division) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information.") -AnnotationAssertion( "up regulation of nuclear division") -AnnotationAssertion( "up-regulation of nuclear division") -AnnotationAssertion( "upregulation of nuclear division") -AnnotationAssertion( "activation of nuclear division") -AnnotationAssertion( "stimulation of nuclear division") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051785") -AnnotationAssertion(rdfs:label "positive regulation of nuclear division") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (short-chain fatty acid biosynthetic process) - -AnnotationAssertion(Annotation( "Wikipedia:Fatty_acid_metabolism") "The chemical reactions and pathways resulting in the formation of a fatty acid with an aliphatic tail of less than 6 carbons.") -AnnotationAssertion( "short chain fatty acid biosynthesis") -AnnotationAssertion( "short chain fatty acid biosynthetic process") -AnnotationAssertion( "short-chain fatty acid anabolism") -AnnotationAssertion( "short-chain fatty acid biosynthesis") -AnnotationAssertion( "short-chain fatty acid formation") -AnnotationAssertion( "short-chain fatty acid synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051790") -AnnotationAssertion(rdfs:label "short-chain fatty acid biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of hair follicle development) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of hair follicle development.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051797") -AnnotationAssertion(rdfs:label "regulation of hair follicle development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of hair follicle development) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of hair follicle development.") -AnnotationAssertion( "up regulation of hair follicle development") -AnnotationAssertion( "up-regulation of hair follicle development") -AnnotationAssertion( "upregulation of hair follicle development") -AnnotationAssertion( "activation of hair follicle development") -AnnotationAssertion( "stimulation of hair follicle development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051798") -AnnotationAssertion(rdfs:label "positive regulation of hair follicle development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of hair follicle development) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of hair follicle development.") -AnnotationAssertion( "down regulation of hair follicle development") -AnnotationAssertion( "down-regulation of hair follicle development") -AnnotationAssertion( "downregulation of hair follicle development") -AnnotationAssertion( "inhibition of hair follicle development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051799") -AnnotationAssertion(rdfs:label "negative regulation of hair follicle development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (glycolipid binding) - -AnnotationAssertion(Annotation( "PMID:19635802") "Binding to a glycolipid, any compound containing one or more monosaccharide residues bound by a glycosidic linkage to a hydrophobic group such as an acylglycerol, a sphingoid, a ceramide (N-acylsphingoid) or a prenyl phosphate.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0051861") -AnnotationAssertion(rdfs:label "glycolipid binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (pigment granule localization) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process in which a pigment granule is transported to, and/or maintained in, a specific location within the cell.") -AnnotationAssertion(Annotation( "GOC:mah") "pigment granule localisation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051875") -AnnotationAssertion(rdfs:label "pigment granule localization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (regulation of cardioblast differentiation) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of cardioblast differentiation, the process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051890") -AnnotationAssertion(rdfs:label "regulation of cardioblast differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of cardioblast differentiation) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of cardioblast differentiation, the process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.") -AnnotationAssertion( "up regulation of cardioblast differentiation") -AnnotationAssertion( "up-regulation of cardioblast differentiation") -AnnotationAssertion( "upregulation of cardioblast differentiation") -AnnotationAssertion( "activation of cardioblast differentiation") -AnnotationAssertion( "stimulation of cardioblast differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051891") -AnnotationAssertion(rdfs:label "positive regulation of cardioblast differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of cardioblast differentiation) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of cardioblast differentiation, the process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.") -AnnotationAssertion( "down regulation of cardioblast differentiation") -AnnotationAssertion( "down-regulation of cardioblast differentiation") -AnnotationAssertion( "downregulation of cardioblast differentiation") -AnnotationAssertion( "inhibition of cardioblast differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051892") -AnnotationAssertion(rdfs:label "negative regulation of cardioblast differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (pigment granule transport) - -AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of pigment granules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion( "pigment granule translocation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051904") -AnnotationAssertion(rdfs:label "pigment granule transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (establishment of pigment granule localization) - -AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of a pigment granule to a specific location.") -AnnotationAssertion(Annotation( "GOC:mah") "establishment of pigment granule localisation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051905") -AnnotationAssertion(rdfs:label "establishment of pigment granule localization") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (regulation of calcium ion transport) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of the directed movement of calcium ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion( "regulation of calcium transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051924") -AnnotationAssertion(rdfs:label "regulation of calcium ion transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of calcium ion transport) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of calcium ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion( "down regulation of calcium ion transport") -AnnotationAssertion( "down-regulation of calcium ion transport") -AnnotationAssertion( "downregulation of calcium ion transport") -AnnotationAssertion( "negative regulation of calcium transport") -AnnotationAssertion( "inhibition of calcium ion transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051926") -AnnotationAssertion(rdfs:label "negative regulation of calcium ion transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of calcium ion transport) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of the directed movement of calcium ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion( "positive regulation of calcium transport") -AnnotationAssertion( "up regulation of calcium ion transport") -AnnotationAssertion( "up-regulation of calcium ion transport") -AnnotationAssertion( "upregulation of calcium ion transport") -AnnotationAssertion( "activation of calcium ion transport") -AnnotationAssertion( "stimulation of calcium ion transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051928") -AnnotationAssertion(rdfs:label "positive regulation of calcium ion transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of sensory perception of pain) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of the sensory perception of pain, the series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051930") -AnnotationAssertion(rdfs:label "regulation of sensory perception of pain") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of sensory perception) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of sensory perception, the series of events required for an organism to receive a sensory stimulus, convert it to a molecular signal, and recognize and characterize the signal.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051931") -AnnotationAssertion(rdfs:label "regulation of sensory perception") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (synaptic transmission, GABAergic) - -AnnotationAssertion(Annotation( "GOC:dos") Annotation( "ISBN:0126603030") "The vesicular release of gamma-aminobutyric acid (GABA). from a presynapse, across a chemical synapse, the subsequent activation of GABA receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.") -AnnotationAssertion( "GABAergic synaptic transmission") -AnnotationAssertion( "synaptic transmission, GABA mediated") -AnnotationAssertion( "synaptic transmission, gamma-aminobutyric acid mediated") -AnnotationAssertion( "synaptic transmission, gamma-aminobutyric acid-ergic") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051932") -AnnotationAssertion(rdfs:label "synaptic transmission, GABAergic") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (catecholamine transport) - -AnnotationAssertion(Annotation( "GOC:ai") Annotation( "ISBN:0198506732") "The directed movement of catecholamines, a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051937") -AnnotationAssertion(rdfs:label "catecholamine transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (L-glutamate import) - -AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:jsg") Annotation( "GOC:mah") "The directed movement of L-glutamate, the L-enantiomer of the anion of 2-aminopentanedioic acid, into a cell or organelle.") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "L-glutamate uptake") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051938") -AnnotationAssertion(rdfs:label "L-glutamate import") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (gamma-aminobutyric acid import) - -AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of gamma-aminobutyric acid (GABA, 4-aminobutyrate) into a cell or organelle.") -AnnotationAssertion( "4-aminobutyrate import") -AnnotationAssertion( "GABA import") -AnnotationAssertion( "gamma-aminobutyrate import") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "gamma-aminobutyric acid uptake") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051939") -AnnotationAssertion(rdfs:label "gamma-aminobutyric acid import") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of amine transport) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051952") -AnnotationAssertion(rdfs:label "regulation of amine transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (negative regulation of amine transport) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion( "down regulation of amine transport") -AnnotationAssertion( "down-regulation of amine transport") -AnnotationAssertion( "downregulation of amine transport") -AnnotationAssertion( "inhibition of amine transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051953") -AnnotationAssertion(rdfs:label "negative regulation of amine transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of amine transport) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion( "up regulation of amine transport") -AnnotationAssertion( "up-regulation of amine transport") -AnnotationAssertion( "upregulation of amine transport") -AnnotationAssertion( "activation of amine transport") -AnnotationAssertion( "stimulation of amine transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051954") -AnnotationAssertion(rdfs:label "positive regulation of amine transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of amino acid transport) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051955") -AnnotationAssertion(rdfs:label "regulation of amino acid transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (negative regulation of amino acid transport) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion( "down regulation of amino acid transport") -AnnotationAssertion( "down-regulation of amino acid transport") -AnnotationAssertion( "downregulation of amino acid transport") -AnnotationAssertion(Annotation( "GOC:mah") "negative regulation of amino acid transmembrane transport") -AnnotationAssertion( "inhibition of amino acid transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051956") -AnnotationAssertion(rdfs:label "negative regulation of amino acid transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (positive regulation of amino acid transport) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion(Annotation( "GOC:mah") "positive regulation of amino acid transmembrane transport") -AnnotationAssertion( "up regulation of amino acid transport") -AnnotationAssertion( "up-regulation of amino acid transport") -AnnotationAssertion( "upregulation of amino acid transport") -AnnotationAssertion( "activation of amino acid transport") -AnnotationAssertion( "stimulation of amino acid transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051957") -AnnotationAssertion(rdfs:label "positive regulation of amino acid transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of nervous system development) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051960") -AnnotationAssertion(rdfs:label "regulation of nervous system development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (negative regulation of nervous system development) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue.") -AnnotationAssertion( "down regulation of nervous system development") -AnnotationAssertion( "down-regulation of nervous system development") -AnnotationAssertion( "downregulation of nervous system development") -AnnotationAssertion( "inhibition of nervous system development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051961") -AnnotationAssertion(rdfs:label "negative regulation of nervous system development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of nervous system development) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates, maintains or increases the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue.") -AnnotationAssertion( "up regulation of nervous system development") -AnnotationAssertion( "up-regulation of nervous system development") -AnnotationAssertion( "upregulation of nervous system development") -AnnotationAssertion( "activation of nervous system development") -AnnotationAssertion( "stimulation of nervous system development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051962") -AnnotationAssertion(rdfs:label "positive regulation of nervous system development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of synapse assembly) - -AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:pr") "Any process that modulates the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse.") -AnnotationAssertion( "regulation of synapse biogenesis") -AnnotationAssertion( "regulation of synaptogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051963") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "regulation of synapse assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of synapse assembly) - -AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:pr") "Any process that stops, prevents, or reduces the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse.") -AnnotationAssertion( "down regulation of synapse assembly") -AnnotationAssertion( "down-regulation of synapse assembly") -AnnotationAssertion( "downregulation of synapse assembly") -AnnotationAssertion( "negative regulation of synapse biogenesis") -AnnotationAssertion( "negative regulation of synaptogenesis") -AnnotationAssertion( "inhibition of synapse assembly") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051964") -AnnotationAssertion(rdfs:label "negative regulation of synapse assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (positive regulation of synapse assembly) - -AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:pr") "Any process that activates, maintains or increases the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse.") -AnnotationAssertion( "positive regulation of synapse biogenesis") -AnnotationAssertion( "positive regulation of synaptogenesis") -AnnotationAssertion( "up regulation of synapse assembly") -AnnotationAssertion( "up-regulation of synapse assembly") -AnnotationAssertion( "upregulation of synapse assembly") -AnnotationAssertion( "activation of synapse assembly") -AnnotationAssertion( "stimulation of synapse assembly") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051965") -AnnotationAssertion(rdfs:label "positive regulation of synapse assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of synaptic transmission, glutamatergic) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051966") -AnnotationAssertion(rdfs:label "regulation of synaptic transmission, glutamatergic") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of synaptic transmission, glutamatergic) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate.") -AnnotationAssertion( "down regulation of synaptic transmission, glutamatergic") -AnnotationAssertion( "down-regulation of synaptic transmission, glutamatergic") -AnnotationAssertion( "downregulation of synaptic transmission, glutamatergic") -AnnotationAssertion( "inhibition of synaptic transmission, glutamatergic") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051967") -AnnotationAssertion(rdfs:label "negative regulation of synaptic transmission, glutamatergic") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of synaptic transmission, glutamatergic) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates, maintains or increases the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate.") -AnnotationAssertion( "up regulation of synaptic transmission, glutamatergic") -AnnotationAssertion( "up-regulation of synaptic transmission, glutamatergic") -AnnotationAssertion( "upregulation of synaptic transmission, glutamatergic") -AnnotationAssertion( "activation of synaptic transmission, glutamatergic") -AnnotationAssertion( "stimulation of synaptic transmission, glutamatergic") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051968") -AnnotationAssertion(rdfs:label "positive regulation of synaptic transmission, glutamatergic") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of transmission of nerve impulse) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation.") -AnnotationAssertion(Annotation( "GOC:dph") "regulation of conduction of nerve impulse") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051969") -AnnotationAssertion(rdfs:label "regulation of transmission of nerve impulse") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (negative regulation of transmission of nerve impulse) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation.") -AnnotationAssertion( "down regulation of transmission of nerve impulse") -AnnotationAssertion( "down-regulation of transmission of nerve impulse") -AnnotationAssertion( "downregulation of transmission of nerve impulse") -AnnotationAssertion(Annotation( "GOC:dph") "negative regulation of conduction of nerve impulse") -AnnotationAssertion( "inhibition of transmission of nerve impulse") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051970") -AnnotationAssertion(rdfs:label "negative regulation of transmission of nerve impulse") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (positive regulation of transmission of nerve impulse) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates, maintains or increases the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation.") -AnnotationAssertion(Annotation( "GOC:dph") "positive regulation of conduction of nerve impulse") -AnnotationAssertion( "up regulation of transmission of nerve impulse") -AnnotationAssertion( "up-regulation of transmission of nerve impulse") -AnnotationAssertion( "upregulation of transmission of nerve impulse") -AnnotationAssertion( "activation of transmission of nerve impulse") -AnnotationAssertion( "stimulation of transmission of nerve impulse") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051971") -AnnotationAssertion(rdfs:label "positive regulation of transmission of nerve impulse") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of chromosome segregation) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051983") -AnnotationAssertion(rdfs:label "regulation of chromosome segregation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of chromosome segregation) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets.") -AnnotationAssertion( "up regulation of chromosome segregation") -AnnotationAssertion( "up-regulation of chromosome segregation") -AnnotationAssertion( "upregulation of chromosome segregation") -AnnotationAssertion( "activation of chromosome segregation") -AnnotationAssertion( "stimulation of chromosome segregation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051984") -AnnotationAssertion(rdfs:label "positive regulation of chromosome segregation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of chromosome segregation) - -AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets.") -AnnotationAssertion( "down regulation of chromosome segregation") -AnnotationAssertion( "down-regulation of chromosome segregation") -AnnotationAssertion( "downregulation of chromosome segregation") -AnnotationAssertion( "inhibition of chromosome segregation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0051985") -AnnotationAssertion(rdfs:label "negative regulation of chromosome segregation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (imidazole-containing compound metabolic process) AnnotationAssertion(Annotation( "GOC:curators") "The chemical reactions and pathways involving imidazoles, five-membered organic heterocycle containing two nitrogen atoms at positions 1 and 3, or any of its derivatives; compounds containing an imidazole skeleton.") @@ -95910,321 +26803,12 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0052803") AnnotationAssertion(rdfs:label "imidazole-containing compound metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) -# Class: (imidazole-containing compound catabolic process) - -AnnotationAssertion(Annotation( "GOC:curators") "The chemical reactions and pathways resulting in the breakdown of imidazoles, five-membered organic heterocycle containing two nitrogen atoms at positions 1 and 3, or any of its derivatives; compounds containing an imidazole skeleton.") -AnnotationAssertion( "imidazole breakdown") -AnnotationAssertion( "imidazole catabolism") -AnnotationAssertion( "imidazole degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0052805") -AnnotationAssertion(rdfs:label "imidazole-containing compound catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (muscle cell development) - -AnnotationAssertion(Annotation( "CL:0000187") Annotation( "GOC:devbiol") "The process whose specific outcome is the progression of a muscle cell over time, from its formation to the mature structure. Muscle cell development does not include the steps involved in committing an unspecified cell to the muscle cell fate.") -AnnotationAssertion( "GO:0048747") -AnnotationAssertion( "muscle fiber development") -AnnotationAssertion( "muscle fibre development") -AnnotationAssertion( "myofiber development") -AnnotationAssertion( "myofibre development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0055001") -AnnotationAssertion(rdfs:label "muscle cell development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (striated muscle cell development) - -AnnotationAssertion(Annotation( "CL:0000737") Annotation( "GOC:devbiol") "The process whose specific outcome is the progression of a striated muscle cell over time, from its formation to the mature structure. Striated muscle cells contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0055002") -AnnotationAssertion(rdfs:label "striated muscle cell development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cardiac myofibril assembly) - -AnnotationAssertion(Annotation( "GOC:devbiol") "The process whose specific outcome is the progression of the cardiac myofibril over time, from its formation to the mature structure. A cardiac myofibril is a myofibril specific to cardiac muscle cells.") -AnnotationAssertion( "cardiac myofibril development") -AnnotationAssertion( "cardiac myofibril morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "heart myofibril assembly") -AnnotationAssertion( "GO:0055003") -AnnotationAssertion(rdfs:label "cardiac myofibril assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cardiac cell development) - -AnnotationAssertion(Annotation( "GOC:devbiol") "The process whose specific outcome is the progression of a cardiac cell over time, from its formation to the mature state. A cardiac cell is a cell that will form part of the cardiac organ of an individual.") -AnnotationAssertion(Annotation( "GOC:dph") "cardiocyte development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "heart cell development") -AnnotationAssertion( "GO:0055006") -AnnotationAssertion(rdfs:label "cardiac cell development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cardiac muscle cell differentiation) - -AnnotationAssertion(Annotation( "GOC:devbiol") Annotation( "GOC:mtg_heart") "The process in which a cardiac muscle precursor cell acquires specialized features of a cardiac muscle cell. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction.") -AnnotationAssertion( "cardiomyocyte differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "heart muscle cell differentiation") -AnnotationAssertion( "GO:0055007") -AnnotationAssertion(rdfs:label "cardiac muscle cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cardiac muscle tissue morphogenesis) - -AnnotationAssertion(Annotation( "GOC:devbiol") "The process in which the anatomical structures of cardiac muscle tissue are generated and organized.") -AnnotationAssertion(Annotation( "GOC:mtg_heart") "myocardium morphogenesis") -AnnotationAssertion( "heart muscle morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0055008") -AnnotationAssertion(rdfs:label "cardiac muscle tissue morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (atrial cardiac muscle tissue morphogenesis) - -AnnotationAssertion(Annotation( "GOC:devbiol") "The process in which the anatomical structure of cardiac atrium muscle is generated and organized.") -AnnotationAssertion( "atrial heart muscle morphogenesis") -AnnotationAssertion(Annotation( "GOC:mtg_heart") "atrial myocardium morphogenesis") -AnnotationAssertion( "cardiac atrium muscle morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0055009") -AnnotationAssertion(rdfs:label "atrial cardiac muscle tissue morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (ventricular cardiac muscle tissue morphogenesis) - -AnnotationAssertion(Annotation( "GOC:devbiol") "The process in which the anatomical structures of cardiac ventricle muscle is generated and organized.") -AnnotationAssertion( "cardiac ventricle muscle morphogenesis") -AnnotationAssertion( "ventricular heart muscle morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0055010") -AnnotationAssertion(rdfs:label "ventricular cardiac muscle tissue morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cardiac muscle cell development) - -AnnotationAssertion(Annotation( "GOC:devbiol") Annotation( "GOC:mtg_heart") "The process whose specific outcome is the progression of a cardiac muscle cell over time, from its formation to the mature state.") -AnnotationAssertion( "GO:0048739") -AnnotationAssertion( "cardiac muscle fiber development") -AnnotationAssertion( "cardiac muscle fibre development") -AnnotationAssertion(Annotation( "GOC:mtg_muscle") "cardiomyocyte cell development") -AnnotationAssertion( "heart muscle cell development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "heart muscle fiber development") -AnnotationAssertion( "GO:0055013") -AnnotationAssertion(rdfs:label "cardiac muscle cell development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (hypochord development) - -AnnotationAssertion(Annotation( "GOC:devbiol") Annotation( "GOC:lb") "The process whose specific outcome is the progression of the hypochord over time, from its formation to the mature structure. The hypochord is a transient rod-like structure in the embryos of fish, lampreys and amphibians that is located immediately ventral to the notochord. The hypochord may play a role in positioning the dorsal aorta.") -AnnotationAssertion( "subnotochordal rod development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0055016") -AnnotationAssertion(rdfs:label "hypochord development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (cardiac muscle tissue growth) - -AnnotationAssertion(Annotation( "GOC:devbiol") "The increase in size or mass of a cardiac muscle, where the increase in size or mass has the specific outcome of the progression of the organism over time from one condition to another.") -AnnotationAssertion( "heart muscle growth") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0055017") -AnnotationAssertion(rdfs:label "cardiac muscle tissue growth") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (regulation of cardiac muscle fiber development) - -AnnotationAssertion(Annotation( "GOC:vk") "Any process that modulates the frequency, rate or extent of cardiac muscle fiber development.") -AnnotationAssertion( "regulation of cardiac muscle fibre development") -AnnotationAssertion( "regulation of heart muscle fiber development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0055018") -AnnotationAssertion(rdfs:label "regulation of cardiac muscle fiber development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (negative regulation of cardiac muscle fiber development) - -AnnotationAssertion(Annotation( "GOC:vk") "Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle fiber development.") -AnnotationAssertion( "down regulation of cardiac muscle fiber development") -AnnotationAssertion( "down-regulation of cardiac muscle fiber development") -AnnotationAssertion( "downregulation of cardiac muscle fiber development") -AnnotationAssertion( "negative regulation of cardiac muscle fibre development") -AnnotationAssertion( "inhibition of cardiac muscle fiber development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "negative regulation of heart muscle fiber development") -AnnotationAssertion( "GO:0055019") -AnnotationAssertion(rdfs:label "negative regulation of cardiac muscle fiber development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (positive regulation of cardiac muscle fiber development) - -AnnotationAssertion(Annotation( "GOC:vk") "Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle fiber development.") -AnnotationAssertion( "positive regulation of cardiac muscle fibre development") -AnnotationAssertion( "positive regulation of heart muscle fiber development") -AnnotationAssertion( "up regulation of cardiac muscle fiber development") -AnnotationAssertion( "up-regulation of cardiac muscle fiber development") -AnnotationAssertion( "upregulation of cardiac muscle fiber development") -AnnotationAssertion( "activation of cardiac muscle fiber development") -AnnotationAssertion( "stimulation of cardiac muscle fiber development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0055020") -AnnotationAssertion(rdfs:label "positive regulation of cardiac muscle fiber development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (regulation of cardiac muscle tissue growth) - -AnnotationAssertion(Annotation( "GOC:vk") "Any process that modulates the frequency, rate or extent of cardiac muscle growth.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0055021") -AnnotationAssertion(rdfs:label "regulation of cardiac muscle tissue growth") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (negative regulation of cardiac muscle tissue growth) - -AnnotationAssertion(Annotation( "GOC:vk") "Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle growth.") -AnnotationAssertion( "down regulation of cardiac muscle growth") -AnnotationAssertion( "down-regulation of cardiac muscle growth") -AnnotationAssertion( "downregulation of cardiac muscle growth") -AnnotationAssertion( "inhibition of cardiac muscle growth") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "negative regulation of heart muscle growth") -AnnotationAssertion( "GO:0055022") -AnnotationAssertion(rdfs:label "negative regulation of cardiac muscle tissue growth") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (positive regulation of cardiac muscle tissue growth) - -AnnotationAssertion(Annotation( "GOC:vk") "Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle growth.") -AnnotationAssertion( "positive regulation of heart muscle growth") -AnnotationAssertion( "up regulation of cardiac muscle growth") -AnnotationAssertion( "up-regulation of cardiac muscle growth") -AnnotationAssertion( "upregulation of cardiac muscle growth") -AnnotationAssertion( "activation of cardiac muscle growth") -AnnotationAssertion( "stimulation of cardiac muscle growth") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0055023") -AnnotationAssertion(rdfs:label "positive regulation of cardiac muscle tissue growth") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of cardiac muscle tissue development) - -AnnotationAssertion(Annotation( "GOC:vk") "Any process that modulates the frequency, rate or extent of cardiac muscle tissue development.") -AnnotationAssertion( "regulation of heart muscle development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0055024") -AnnotationAssertion(rdfs:label "regulation of cardiac muscle tissue development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of cardiac muscle tissue development) - -AnnotationAssertion(Annotation( "GOC:vk") "Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle tissue development.") -AnnotationAssertion( "positive regulation of heart muscle development") -AnnotationAssertion( "up regulation of cardiac muscle development") -AnnotationAssertion( "up-regulation of cardiac muscle development") -AnnotationAssertion( "upregulation of cardiac muscle development") -AnnotationAssertion( "activation of cardiac muscle development") -AnnotationAssertion( "stimulation of cardiac muscle development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0055025") -AnnotationAssertion(rdfs:label "positive regulation of cardiac muscle tissue development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of cardiac muscle tissue development) - -AnnotationAssertion(Annotation( "GOC:vk") "Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle tissue development.") -AnnotationAssertion( "down regulation of cardiac muscle development") -AnnotationAssertion( "down-regulation of cardiac muscle development") -AnnotationAssertion( "downregulation of cardiac muscle development") -AnnotationAssertion( "negative regulation of heart muscle development") -AnnotationAssertion( "inhibition of cardiac muscle development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0055026") -AnnotationAssertion(rdfs:label "negative regulation of cardiac muscle tissue development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (neuroblast division) - -AnnotationAssertion(Annotation( "PMID:11163136") Annotation( "PMID:11250167") "The process resulting in the physical partitioning and separation of a neuroblast into daughter cells. A neuroblast is any cell that will divide and give rise to a neuron.") -AnnotationAssertion( "neuroblast cell division") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0055057") -AnnotationAssertion(rdfs:label "neuroblast division") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (asymmetric neuroblast division) - -AnnotationAssertion(Annotation( "GOC:dph") "The process resulting in the physical partitioning and separation of a neuroblast into two daughter cells with different developmental potentials.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0055059") -AnnotationAssertion(rdfs:label "asymmetric neuroblast division") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (phosphate ion homeostasis) - -AnnotationAssertion(Annotation( "GOC:jid") Annotation( "GOC:mah") "Any process involved in the maintenance of an internal steady state of phosphate ions within an organism or cell.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0055062") -AnnotationAssertion(rdfs:label "phosphate ion homeostasis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (sulfate ion homeostasis) - -AnnotationAssertion(Annotation( "GOC:jid") Annotation( "GOC:mah") "Any process involved in the maintenance of an internal steady state of sulfate ions within an organism or cell.") -AnnotationAssertion( "GO:0080174") -AnnotationAssertion( "sulfate homeostasis") -AnnotationAssertion( "sulphate ion homeostasis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0055063") -AnnotationAssertion(rdfs:label "sulfate ion homeostasis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (calcium ion homeostasis) AnnotationAssertion(Annotation( "GOC:ceb") Annotation( "GOC:jid") Annotation( "GOC:mah") "Any process involved in the maintenance of an internal steady state of calcium ions within an organism or cell.") @@ -96232,7 +26816,6 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0055074") AnnotationAssertion(rdfs:label "calcium ion homeostasis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (sodium ion homeostasis) @@ -96240,7 +26823,6 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:0055078") AnnotationAssertion(rdfs:label "sodium ion homeostasis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (monoatomic cation homeostasis) @@ -96250,142 +26832,6 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0055080") AnnotationAssertion(rdfs:label "monoatomic cation homeostasis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (intracellular chemical homeostasis) - -AnnotationAssertion(Annotation( "GOC:isa_complete") Annotation( "GOC:jid") "A homeostatic process involved in the maintenance of a steady state level of a chemical within a cell.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/24514"^^xsd:anyURI) -AnnotationAssertion( "cellular chemical homeostasis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0055082") -AnnotationAssertion(rdfs:label "intracellular chemical homeostasis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (transmembrane transport) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:jid") "The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2015-10-21T13:22:47Z") -AnnotationAssertion( "GO:0090662") -AnnotationAssertion( "membrane transport") -AnnotationAssertion( "ATP hydrolysis coupled transmembrane transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0055085") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "Transmembrane transport is the transport of a solute across a lipid bilayer. Note that transport through the nuclear pore complex is not transmembrane because the nuclear membrane is a double membrane and is not traversed. For transport through the nuclear pore, consider instead the term 'nucleocytoplasmic transport ; GO:0006913' and its children. Note also that this term is not intended for use in annotating lateral movement within membranes.") -AnnotationAssertion(rdfs:label "transmembrane transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (nucleobase-containing small molecule metabolic process) - -AnnotationAssertion(Annotation( "GOC:vw") "The cellular chemical reactions and pathways involving a nucleobase-containing small molecule: a nucleobase, a nucleoside, or a nucleotide.") -AnnotationAssertion( "nucleobase, nucleoside and nucleotide metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "nucleobase, nucleoside and nucleotide metabolic process") -AnnotationAssertion( "GO:0055086") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "nucleobase-containing small molecule metabolic process") -SubClassOf( ) -SubClassOf( ) - -# Class: (lipid homeostasis) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:rl") "Any process involved in the maintenance of an internal steady state of lipid within an organism or cell.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0055088") -AnnotationAssertion(rdfs:label "lipid homeostasis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (fatty acid homeostasis) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:rl") "Any process involved in the maintenance of an internal steady state of fatty acid within an organism or cell.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0055089") -AnnotationAssertion(rdfs:label "fatty acid homeostasis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (phospholipid homeostasis) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:rl") "Any process involved in the maintenance of an internal steady state of phospholipid within an organism or cell.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0055091") -AnnotationAssertion(rdfs:label "phospholipid homeostasis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (response to lipoprotein particle) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:rl") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoprotein particle stimulus.") -AnnotationAssertion(Annotation( "GOC:dos") "response to lipoprotein particle stimulus") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0055094") -AnnotationAssertion(rdfs:label "response to lipoprotein particle") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (Golgi to secretory granule transport) - -AnnotationAssertion(Annotation( "GOC:curators") "The directed movement of proteins from the Golgi to a secretory granule. The secretory granule is a membrane-bounded particle, usually protein, formed in the granular endoplasmic reticulum and the Golgi complex.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0055107") -AnnotationAssertion(rdfs:label "Golgi to secretory granule transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (Golgi to transport vesicle transport) - -AnnotationAssertion(Annotation( "GOC:jid") "The directed movement of proteins from the Golgi to a transport vesicle. Continuously secreted proteins are sorted into transport vesicles that fuse with the plasma membrane, releasing their contents by exocytosis.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0055108") -AnnotationAssertion(rdfs:label "Golgi to transport vesicle transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (ingression involved in gastrulation with mouth forming second) - -AnnotationAssertion(Annotation( "ISBN:0878932437") "The migration of individual cells into the embryo involved in deuterostomic gastrulation.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0055111") -AnnotationAssertion(rdfs:label "ingression involved in gastrulation with mouth forming second") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of cardiac muscle contraction) - -AnnotationAssertion(Annotation( "GOC:ecd") "Any process that modulates the frequency, rate or extent of cardiac muscle contraction.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0055117") -AnnotationAssertion(rdfs:label "regulation of cardiac muscle contraction") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of cardiac muscle contraction) - -AnnotationAssertion(Annotation( "GOC:ecd") "Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle contraction.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0055118") -AnnotationAssertion(rdfs:label "negative regulation of cardiac muscle contraction") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (digestive system development) - -AnnotationAssertion(Annotation( "GOC:jid") "The process whose specific outcome is the progression of the digestive system over time, from its formation to the mature structure. The digestive system is the entire structure in which digestion takes place. Digestion is all of the physical, chemical, and biochemical processes carried out by multicellular organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0055123") -AnnotationAssertion(rdfs:label "digestive system development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) # Class: (vibrational conductance of sound to the inner ear) @@ -96423,214 +26869,6 @@ AnnotationAssertion( "linear vestibuloocular reflex") SubClassOf( ) -# Class: (Sertoli cell differentiation) - -AnnotationAssertion(Annotation( "GOC:dph") "The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a Sertoli cell. A Sertoli cell is a supporting cell projecting inward from the basement membrane of seminiferous tubules.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060008") -AnnotationAssertion(rdfs:label "Sertoli cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (Sertoli cell development) - -AnnotationAssertion(Annotation( "GOC:dph") "The process whose specific outcome is the progression of a Sertoli cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a Sertoli cell fate.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060009") -AnnotationAssertion(rdfs:label "Sertoli cell development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (Sertoli cell proliferation) - -AnnotationAssertion(Annotation( "GOC:dph") "The multiplication or reproduction of Sertoli cells, resulting in the expansion of the Sertoli cell population. A Sertoli cell is a supporting cell projecting inward from the basement membrane of seminiferous tubules.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060011") -AnnotationAssertion(rdfs:label "Sertoli cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (granulosa cell differentiation) - -AnnotationAssertion(Annotation( "GOC:dph") "The process in which a relatively unspecialized cell acquires the specialized features of a granulosa cell, a supporting cell for the developing female gamete in the ovary of mammals.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060014") -AnnotationAssertion(rdfs:label "granulosa cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (granulosa cell development) - -AnnotationAssertion(Annotation( "GOC:dph") "The process whose specific outcome is the progression of a granulosa cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a granulosa cell fate.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060016") -AnnotationAssertion(rdfs:label "granulosa cell development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (parathyroid gland development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "ISBN:0721662544") "The process whose specific outcome is the progression of the parathyroid gland over time, from its formation to the mature structure. The parathyroid gland is an organ specialised for secretion of parathyroid hormone.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060017") -AnnotationAssertion(rdfs:label "parathyroid gland development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (radial glial cell differentiation) - -AnnotationAssertion(Annotation( "GOC:dph") "The process in which neuroepithelial cells of the neural tube give rise to radial glial cells, specialized bipotential progenitors cells of the brain. Differentiation includes the processes involved in commitment of a cell to a specific fate.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060019") -AnnotationAssertion(rdfs:label "radial glial cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (roof of mouth development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "ISBN:0721662544") "The biological process whose specific outcome is the progression of the roof of the mouth from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The roof of the mouth is the partition that separates the nasal and oral cavities.") -AnnotationAssertion(Annotation( "ISBN:0721662544") "palatum development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060021") -AnnotationAssertion(rdfs:label "roof of mouth development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (hard palate development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "ISBN:0721662544") "The biological process whose specific outcome is the progression of the hard palate from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. The hard palate is the anterior portion of the palate consisting of bone and mucous membranes.") -AnnotationAssertion(Annotation( "ISBN:0721662544") "palatum durum development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060022") -AnnotationAssertion(rdfs:label "hard palate development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (soft palate development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "ISBN:0721662544") "The biological process whose specific outcome is the progression of the soft palate from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. The soft palate is the posterior portion of the palate extending from the posterior edge of the hard palate.") -AnnotationAssertion( ) -AnnotationAssertion(Annotation( "ISBN:0721662544") "palatum molle development") -AnnotationAssertion(Annotation( "ISBN:0721662544") "velum palatum development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060023") -AnnotationAssertion(rdfs:label "soft palate development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) -DisjointClasses( ObjectSomeValuesFrom( )) - -# Class: (pharyngeal system development) - -AnnotationAssertion(Annotation( "GOC:dph") "The process whose specific outcome is the progression of the pharyngeal system over time, from its formation to the mature structure. The pharyngeal system is a transient embryonic complex that is specific to vertebrates. It comprises the pharyngeal arches, bulges of tissues of mesoderm and neural crest derivation through which pass nerves and pharyngeal arch arteries. The arches are separated internally by pharyngeal pouches, evaginations of foregut endoderm, and externally by pharyngeal clefts, invaginations of surface ectoderm. The development of the system ends when the stucture it contributes to are forming: the thymus, thyroid, parathyroids, maxilla, mandible, aortic arch, cardiac outflow tract, external and middle ear.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060037") -AnnotationAssertion(rdfs:label "pharyngeal system development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cardiac muscle cell proliferation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:rph") Annotation( "PMID:11161571") "The expansion of a cardiac muscle cell population by cell division.") -AnnotationAssertion( "cardiac myocyte proliferation") -AnnotationAssertion( "heart muscle cell proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:10074473") "cardiomyocyte proliferation") -AnnotationAssertion( "GO:0060038") -AnnotationAssertion(rdfs:label "cardiac muscle cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (pericardium development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:rph") Annotation( "PMID:15138308") Annotation( "PMID:16376438") "The process whose specific outcome is the progression of the pericardium over time, from its formation to the mature structure. The pericardium is a double-walled sac that contains the heart and the roots of the aorta, vena cava and the pulmonary artery.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060039") -AnnotationAssertion(rdfs:label "pericardium development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (retinal bipolar neuron differentiation) - -AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:bf") Annotation( "GOC:dph") Annotation( "GOC:tb") "The process in which a relatively unspecialized cell acquires specialized features of a bipolar cell, the last neuron to be generated in the retina.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060040") -AnnotationAssertion(rdfs:label "retinal bipolar neuron differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (retina development in camera-type eye) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:dph") Annotation( "ISBN:0815340729") "The process whose specific outcome is the progression of the retina over time, from its formation to the mature structure. The retina is the innermost layer or coating at the back of the eyeball, which is sensitive to light and in which the optic nerve terminates.") -AnnotationAssertion( "GO:0002073") -AnnotationAssertion( "retina development in camera-style eye") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "retinal development") -AnnotationAssertion( "GO:0060041") -AnnotationAssertion(rdfs:label "retina development in camera-type eye") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (retina morphogenesis in camera-type eye) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:dph") Annotation( "GOC:mtg_sensu") "The process in which the anatomical structure of the retina is generated and organized.") -AnnotationAssertion( "retina morphogenesis in camera-style eye") -AnnotationAssertion( "retinogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060042") -AnnotationAssertion(rdfs:label "retina morphogenesis in camera-type eye") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (regulation of cardiac muscle cell proliferation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:rph") "Any process that modulates the frequency, rate or extent of cardiac muscle cell proliferation.") -AnnotationAssertion( "regulation of heart muscle cell proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") "regulation of cardiomyocyte proliferation") -AnnotationAssertion( "GO:0060043") -AnnotationAssertion(rdfs:label "regulation of cardiac muscle cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (negative regulation of cardiac muscle cell proliferation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:rph") "Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle cell proliferation.") -AnnotationAssertion( "negative regulation of heart muscle cell proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060044") -AnnotationAssertion(rdfs:label "negative regulation of cardiac muscle cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of cardiac muscle cell proliferation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:rph") "Any process that activates or increases the frequency, rate or extent of cardiac muscle cell proliferation.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "positive regulation of heart muscle cell proliferation") -AnnotationAssertion( "GO:0060045") -AnnotationAssertion(rdfs:label "positive regulation of cardiac muscle cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - # Class: (heart contraction) AnnotationAssertion(Annotation( "GOC:dph") "The multicellular organismal process in which the heart decreases in volume in a characteristic way to propel blood through the body.") @@ -96650,84 +26888,9 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0060048") AnnotationAssertion(rdfs:label "cardiac muscle contraction") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (positive regulation of epithelial cell proliferation involved in wound healing) - -AnnotationAssertion(Annotation( "GOC:dph") "Any process that activates or increases the rate or extent of epithelial cell proliferation, contributing to the restoration of integrity to a damaged tissue following an injury.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060054") -AnnotationAssertion(rdfs:label "positive regulation of epithelial cell proliferation involved in wound healing") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (angiogenesis involved in wound healing) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:15039218") "Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to a damaged tissue, following an injury.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060055") -AnnotationAssertion(rdfs:label "angiogenesis involved in wound healing") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (Spemann organizer formation) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:dph") "Formation of the specialized region on the dorsalmost side of the embryo that acts as the main signaling center establishing the vertebrate body plan.") -AnnotationAssertion( "Spemann's organizer formation") -AnnotationAssertion( "Spemann-Mangold organizer formation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060061") -AnnotationAssertion(rdfs:label "Spemann organizer formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (uterus development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:ebc") "The reproductive developmental process whose specific outcome is the progression of the uterus over time, from its formation to the mature structure.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "Mullerian tract development") -AnnotationAssertion( "GO:0060065") -AnnotationAssertion(rdfs:label "uterus development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (oviduct development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:ebc") Annotation( "http://www.thefreedictionary.com/oviduct") "The reproductive developmental process whose specific outcome is the progression of an oviduct over time, from its formation to the mature structure. An oviduct is a tube through which an ova passes from the ovary to the uterus, or from the ovary to the outside of the organism.") -AnnotationAssertion(Annotation( "GOC:bf") "fallopian tube development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "Mullerian tract development") -AnnotationAssertion( "GO:0060066") -AnnotationAssertion(rdfs:label "oviduct development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (cervix development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:ebc") "The reproductive developmental process whose specific outcome is the progression of the cervix over time, from its formation to the mature structure.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "Mullerian tract development") -AnnotationAssertion( "GO:0060067") -AnnotationAssertion(rdfs:label "cervix development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (vagina development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:ebc") "The reproductive developmental process whose specific outcome is the progression of the vagina over time, from its formation to the mature structure.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060068") -AnnotationAssertion(rdfs:label "vagina development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - # Class: (micturition) AnnotationAssertion(Annotation( "GOC:dph") "The regulation of body fluids process in which parasympathetic nerves stimulate the bladder wall muscle to contract and expel urine from the body.") @@ -96740,37 +26903,6 @@ AnnotationAssertion(rdfs:label "mict SubClassOf( ) SubClassOf( ) -# Class: (excitatory synapse) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:ef") "A synapse in which an action potential in the presynaptic cell increases the probability of an action potential occurring in the postsynaptic cell.") -AnnotationAssertion( "Wikipedia:Excitatory_synapse") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0060076") -AnnotationAssertion(rdfs:label "excitatory synapse") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of postsynaptic membrane potential) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:ef") "Any process that modulates the potential difference across a post-synaptic membrane.") -AnnotationAssertion( "regulation of post-synaptic membrane potential") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060078") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "regulation of postsynaptic membrane potential") -SubClassOf( ) - -# Class: (excitatory postsynaptic potential) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:ef") "A process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential.") -AnnotationAssertion( "regulation of excitatory post-synaptic membrane potential") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "regulation of EPSP") -AnnotationAssertion( "GO:0060079") -AnnotationAssertion(rdfs:label "excitatory postsynaptic potential") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (eye blink reflex) AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:2913208") "The reflex process in which a mechanical stimulus applied to the eye elicits a response of the eyelid closing.") @@ -96780,277 +26912,6 @@ AnnotationAssertion( "eye blink reflex") SubClassOf( ) -# Class: (smooth muscle contraction involved in micturition) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:15827347") "The process leading to shortening and/or development of tension in the urinary bladder smooth muscle tissue involved in the expulsion urine from the body.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "smooth muscle contraction involved in urination") -AnnotationAssertion(Annotation( "GOC:dph") "urinary bladder smooth muscle contraction involved in micturition") -AnnotationAssertion( "GO:0060083") -AnnotationAssertion(rdfs:label "smooth muscle contraction involved in micturition") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (synaptic transmission involved in micturition) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:15827347") "The process of communication from a neuron to a smooth muscle in the bladder that contributes to the expulsion of urine from the body.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "synaptic transmission involved in urination") -AnnotationAssertion( "GO:0060084") -AnnotationAssertion(rdfs:label "synaptic transmission involved in micturition") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (molecular transducer activity) - -AnnotationAssertion(Annotation( "GOC:dos") Annotation( "GOC:pdt") "A compound molecular function in which an effector function is controlled by one or more regulatory components.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0060089") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "molecular transducer activity") -SubClassOf( ) - -# Class: (serotonin secretion, neurotransmission) - -AnnotationAssertion(Annotation( "GOC:dph") "The regulated release of serotonin by a cell, in which released serotonin acts as a neurotransmitter.") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:tb") "serotonin release, neurotransmission") -AnnotationAssertion( "GO:0060096") -AnnotationAssertion(rdfs:label "serotonin secretion, neurotransmission") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (inner ear receptor cell differentiation) - -AnnotationAssertion(Annotation( "GOC:dph") "The process in which relatively unspecialized cells, acquire specialized structural and/or functional features of inner ear receptor cells. Inner ear receptor cells are mechanorecptors found in the inner ear responsible for transducing signals involved in balance and sensory perception of sound.") -AnnotationAssertion( "inner ear hair cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060113") -AnnotationAssertion(rdfs:label "inner ear receptor cell differentiation") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (vestibular receptor cell differentiation) - -AnnotationAssertion(Annotation( "GOC:dph") "The process in which a relatively unspecialized cell acquires specialized features of a vestibular hair cell.") -AnnotationAssertion( "vestibular hair cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060114") -AnnotationAssertion(rdfs:label "vestibular receptor cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (vestibular receptor cell morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that alters the size or shape of a vestibular receptor cell.") -AnnotationAssertion( "vestibular hair cell morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060116") -AnnotationAssertion(rdfs:label "vestibular receptor cell morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (auditory receptor cell development) - -AnnotationAssertion(Annotation( "GOC:dph") "The process whose specific outcome is the progression of an auditory receptor cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.") -AnnotationAssertion( "auditory hair cell development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060117") -AnnotationAssertion(rdfs:label "auditory receptor cell development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (vestibular receptor cell development) - -AnnotationAssertion(Annotation( "GOC:dph") "The process whose specific outcome is the progression of a vestibular receptor cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.") -AnnotationAssertion( "vestibular hair cell development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060118") -AnnotationAssertion(rdfs:label "vestibular receptor cell development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (inner ear receptor cell development) - -AnnotationAssertion(Annotation( "GOC:dph") "The process whose specific outcome is the progression of an inner ear receptor cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.") -AnnotationAssertion( "inner ear hair cell development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060119") -AnnotationAssertion(rdfs:label "inner ear receptor cell development") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (regulation of growth hormone secretion) - -AnnotationAssertion(Annotation( "GOC:dph") "Any process that modulates the frequency, rate or extent of the regulated release of growth hormone from a cell.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060123") -AnnotationAssertion(rdfs:label "regulation of growth hormone secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of growth hormone secretion) - -AnnotationAssertion(Annotation( "GOC:dph") "Any process that increases the frequency, rate or extent of the regulated release of growth hormone from a cell.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060124") -AnnotationAssertion(rdfs:label "positive regulation of growth hormone secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of growth hormone secretion) - -AnnotationAssertion(Annotation( "GOC:dph") "Any process that decreases or stops the frequency, rate or extent of the regulated release of growth hormone from a cell.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060125") -AnnotationAssertion(rdfs:label "negative regulation of growth hormone secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (somatotropin secreting cell differentiation) - -AnnotationAssertion(Annotation( "GOC:dph") "The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a somatotropin secreting cell. A somatotropin secreting cell is an acidophilic cell of the anterior pituitary that produces growth hormone, somatotropin.") -AnnotationAssertion( "growth hormone secreting cell differentiation") -AnnotationAssertion( "somatotrophin secreting cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "somatotrope differentiation") -AnnotationAssertion( "somatotroph differentiation") -AnnotationAssertion( "somatotropic cell differentiation") -AnnotationAssertion( "somatrophic cell differentiation") -AnnotationAssertion( "GO:0060126") -AnnotationAssertion(rdfs:label "somatotropin secreting cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (prolactin secreting cell differentiation) - -AnnotationAssertion(Annotation( "GOC:dph") "The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a prolactin secreting cell. A prolactin secreting cell is an acidophilic cell of the anterior pituitary that produces prolactin.") -AnnotationAssertion( "epsilon-acidophil differentiation") -AnnotationAssertion( "lactotrope differentiation") -AnnotationAssertion( "lactotroph differentiation") -AnnotationAssertion( "lactotropic cell differentiation") -AnnotationAssertion( "mammotrope differentiation") -AnnotationAssertion( "mammotroph differentiation") -AnnotationAssertion( "mammotrophic cell differentiation") -AnnotationAssertion( "mammotropic cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060127") -AnnotationAssertion(rdfs:label "prolactin secreting cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (corticotropin hormone secreting cell differentiation) - -AnnotationAssertion(Annotation( "GOC:dph") "The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a corticotropic hormone secreting cell. An corticotropic hormone secreting cell is a basophil cell of the anterior pituitary that produces corticotropin.") -AnnotationAssertion( "adrenocorticotrophic hormone secreting cell differentiation") -AnnotationAssertion(Annotation( "GOC:dph") "adrenocorticotropic hormone secreting cell differentiation") -AnnotationAssertion( "corticotrope differentiation") -AnnotationAssertion( "corticotroph differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "corticotrophin hormone secreting cell differentiation") -AnnotationAssertion( "GO:0060128") -AnnotationAssertion(rdfs:label "corticotropin hormone secreting cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (corticotropin hormone secreting cell development) - -AnnotationAssertion(Annotation( "GOC:dph") "The process whose specific outcome is the progression of a corticotropic hormone secreting cell over time, from its formation to the mature structure. An corticotropic hormone secreting cell is a basophil cell of the anterior pituitary that produces corticotropin.") -AnnotationAssertion( "adrenocorticotrophic hormone secreting cell development") -AnnotationAssertion(Annotation( "GOC:dph") "adrenocorticotropic hormone secreting cell development") -AnnotationAssertion( "corticotrope development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "corticotroph development") -AnnotationAssertion( "corticotrophin hormone secreting cell development") -AnnotationAssertion( "GO:0060131") -AnnotationAssertion(rdfs:label "corticotropin hormone secreting cell development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (prolactin secreting cell development) - -AnnotationAssertion(Annotation( "GOC:dph") "The process whose specific outcome is the progression of a prolactin secreting cell over time, from its formation to the mature structure. A prolactin secreting cell is an acidophilic cell of the anterior pituitary that produces prolactin.") -AnnotationAssertion( "epsilon-acidophil development") -AnnotationAssertion( "lactotrope development") -AnnotationAssertion( "lactotroph development") -AnnotationAssertion( "lactotropic cell development") -AnnotationAssertion( "mammotrope development") -AnnotationAssertion( "mammotroph development") -AnnotationAssertion( "mammotrophic cell development") -AnnotationAssertion( "mammotropic cell development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060132") -AnnotationAssertion(rdfs:label "prolactin secreting cell development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (somatotropin secreting cell development) - -AnnotationAssertion(Annotation( "GOC:dph") "The process whose specific outcome is the progression of a somatotropin secreting cell over time, from its formation to the mature structure. A somatotropin secreting cell is an acidophilic cell of the anterior pituitary that produces growth hormone, somatotropin.") -AnnotationAssertion( "growth hormone secreting cell development") -AnnotationAssertion( "somatotrophin secreting cell development") -AnnotationAssertion( "somatotropic cell development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "somatotrope development") -AnnotationAssertion( "somatotroph development") -AnnotationAssertion( "somatrophic cell development") -AnnotationAssertion( "GO:0060133") -AnnotationAssertion(rdfs:label "somatotropin secreting cell development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (maternal process involved in female pregnancy) - -AnnotationAssertion(Annotation( "GOC:dph") "A reproductive process occurring in the mother that allows an embryo or fetus to develop within it.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060135") -AnnotationAssertion(rdfs:label "maternal process involved in female pregnancy") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (embryonic process involved in female pregnancy) - -AnnotationAssertion(Annotation( "GOC:dph") "A reproductive process occurring in the embryo or fetus that allows the embryo or fetus to develop within the mother.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060136") -AnnotationAssertion(rdfs:label "embryonic process involved in female pregnancy") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (regulation of syncytium formation by plasma membrane fusion) - -AnnotationAssertion(Annotation( "GOC:dph") "Any process that modulates the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060142") -AnnotationAssertion(rdfs:label "regulation of syncytium formation by plasma membrane fusion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (positive regulation of syncytium formation by plasma membrane fusion) - -AnnotationAssertion(Annotation( "GOC:dph") "Any process that increases the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060143") -AnnotationAssertion(rdfs:label "positive regulation of syncytium formation by plasma membrane fusion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - # Class: (milk ejection reflex) AnnotationAssertion(Annotation( "GOC:cjm") Annotation( "GOC:dph") Annotation( "GOC:mr") Annotation( "GOC:st") "A reflex that occurs in response to suckling, beginning with a nerve impulse from a receptor in the mammary gland and ending with the ejection of milk from the gland. Signaling never reaches a level of consciousness.") @@ -97065,100 +26926,6 @@ SubClassOf( ObjectSomeValuesFrom( ObjectSomeValuesFrom( )) SubClassOf( ObjectAllValuesFrom( )) -# Class: (urinary bladder development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:ln") Annotation( "GOC:mr") Annotation( "PMID:11768524") Annotation( "PMID:18276178") Annotation( "PMID:538956") "The process whose specific outcome is the progression of the urinary bladder over time, from its formation to the mature structure. The urinary bladder is an elastic, muscular sac situated in the anterior part of the pelvic cavity in which urine collects before excretion.") -AnnotationAssertion( ) -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060157") -AnnotationAssertion(rdfs:label "urinary bladder development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) -DisjointClasses( ObjectSomeValuesFrom( )) - -# Class: (olfactory pit development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "ISBN:0124020607") "The biological process whose specific outcome is the progression of the olfactory pit from an initial condition to its mature state. This process begins with the formation of the olfactory pit, which is an indentation of the olfactory placode, and ends when the pits hollows out to form the nasopharynx.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/22589"^^xsd:anyURI) -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060166") -AnnotationAssertion(rdfs:label "olfactory pit development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (regulation of adenosine receptor signaling pathway) - -AnnotationAssertion(Annotation( "GOC:dph") "Any process that modulates the frequency, rate or extent of the adenosine receptor signaling pathway. The adenosine receptor pathway is the series of molecular signals generated as a consequence of an adenosine receptor binding to one of its physiological ligands.") -AnnotationAssertion(Annotation( "GOC:mah") "regulation of adenosine receptor signalling pathway") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060167") -AnnotationAssertion(rdfs:label "regulation of adenosine receptor signaling pathway") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of adenosine receptor signaling pathway) - -AnnotationAssertion(Annotation( "GOC:dph") "Any process that activates or increases the frequency, rate or extent of the adenosine receptor signaling pathway. The adenosine receptor pathway is the series of molecular signals generated as a consequence of an adenosine receptor binding to one of its physiological ligands.") -AnnotationAssertion(Annotation( "GOC:mah") "positive regulation of adenosine receptor signalling pathway") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060168") -AnnotationAssertion(rdfs:label "positive regulation of adenosine receptor signaling pathway") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of adenosine receptor signaling pathway) - -AnnotationAssertion(Annotation( "GOC:dph") "Any process that stops, prevents, or reduces the frequency, rate or extent of the adenosine receptor signaling pathway. The adenosine receptor pathway is the series of molecular signals generated as a consequence of an adenosine receptor binding to one of its physiological ligands.") -AnnotationAssertion(Annotation( "GOC:mah") "negative regulation of adenosine receptor signalling pathway") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060169") -AnnotationAssertion(rdfs:label "negative regulation of adenosine receptor signaling pathway") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (ciliary membrane) - -AnnotationAssertion(Annotation( "GOC:cilia") Annotation( "GOC:dph") Annotation( "GOC:rph") "The portion of the plasma membrane surrounding a cilium.") -AnnotationAssertion( "GO:0020017") -AnnotationAssertion( "cilial membrane") -AnnotationAssertion( "cilium membrane") -AnnotationAssertion( "flagellar membrane") -AnnotationAssertion( "flagellum membrane") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0060170") -AnnotationAssertion(rdfs:comment "Note that cilia and eukaryotic flagella are deemed to be equivalent.") -AnnotationAssertion(rdfs:label "ciliary membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (limb development) - -AnnotationAssertion(Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "PMID:11487378") "The process whose specific outcome is the progression of a limb over time, from its formation to the mature structure. A limb is an appendage of an animal used for locomotion or grasping. Examples include legs, arms or some types of fin.") -AnnotationAssertion( "Wikipedia:Limb_development") -AnnotationAssertion( "paired limb/fin development") -AnnotationAssertion(Annotation( "GOC:dph") "limb bud development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060173") -AnnotationAssertion(rdfs:label "limb development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (limb bud formation) - -AnnotationAssertion(Annotation( "GOC:dgh") Annotation( "GOC:dph") "The process pertaining to the initial formation of a limb bud from unspecified parts. This process begins with the formation of a local condensation of mesenchyme cells within the prospective limb field, and ends when a limb bud is recognizable.") -AnnotationAssertion( "limb formation") -AnnotationAssertion( "limbbud formation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060174") -AnnotationAssertion(rdfs:label "limb bud formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (estrous cycle phase) AnnotationAssertion(Annotation( "GOC:dph") "The progression of physiological phases, occurring in the endometrium during the estrous cycle that recur at regular intervals during the reproductive years. The estrous cycle is an ovulation cycle where the endometrium is resorbed if pregnancy does not occur.") @@ -97180,106 +26947,6 @@ AnnotationAssertion(rdfs:comment "No AnnotationAssertion(rdfs:label "estrus") SubClassOf( ) -# Class: (endocardium formation) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:dph") Annotation( "PMID:17722983") "Formation of the endocardium of the heart. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060214") -AnnotationAssertion(rdfs:label "endocardium formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (hematopoietic stem cell differentiation) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:bf") Annotation( "GOC:dph") Annotation( "GOC:rl") Annotation( "PMID:15378083") "The process in which a relatively unspecialized cell acquires specialized features of a hematopoietic stem cell. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells.") -AnnotationAssertion( "haematopoietic stem cell differentiation") -AnnotationAssertion( "haemopoietic stem cell differentiation") -AnnotationAssertion( "hemopoietic stem cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060218") -AnnotationAssertion(rdfs:label "hematopoietic stem cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (camera-type eye photoreceptor cell differentiation) - -AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "The process in which a relatively unspecialized cell acquires the specialized features of a photoreceptor cell in a camera-type eye.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060219") -AnnotationAssertion(rdfs:label "camera-type eye photoreceptor cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (retinal rod cell differentiation) - -AnnotationAssertion(Annotation( "GOC:dph") "The process in which a relatively unspecialized cell acquires the specialized features of a retinal rod cell.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060221") -AnnotationAssertion(rdfs:label "retinal rod cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (mesenchymal to epithelial transition) - -AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "A transition where a mesenchymal cell establishes apical/basolateral polarity, forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell.") -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:rl") "epithelial cell differentiation from mesenchymal cell") -AnnotationAssertion(Annotation( "GOC:dph") "mesenchymal-epithelial transition") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060231") -AnnotationAssertion(rdfs:label "mesenchymal to epithelial transition") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (anatomical structure homeostasis) - -AnnotationAssertion(Annotation( "GOC:dph") "A homeostatic process involved in the maintenance of an internal steady state within a defined anatomical structure of an organism, including control of cellular proliferation and death and control of metabolic function. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.") -AnnotationAssertion(Annotation( "GOC:dph") "anatomical structure maintenance") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060249") -AnnotationAssertion(rdfs:label "anatomical structure homeostasis") -SubClassOf( ) - -# Class: (regulation of glial cell proliferation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the frequency, rate or extent of glial cell proliferation.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060251") -AnnotationAssertion(rdfs:label "regulation of glial cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of glial cell proliferation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:sl") Annotation( "GOC:tb") "Any process that activates or increases the rate or extent of glial cell proliferation.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060252") -AnnotationAssertion(rdfs:label "positive regulation of glial cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (negative regulation of glial cell proliferation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:sl") Annotation( "GOC:tb") "Any process that stops or decreases the rate or extent of glial cell proliferation.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060253") -AnnotationAssertion(rdfs:label "negative regulation of glial cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of macromolecule metabolic process) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060255") -AnnotationAssertion(rdfs:label "regulation of macromolecule metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - # Class: (regulation of feeding behavior) AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the rate, frequency or extent of the behavior associated with the intake of food.") @@ -97287,341 +26954,14 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:0060259") AnnotationAssertion(rdfs:label "regulation of feeding behavior") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (cilium assembly) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:cilia") Annotation( "GOC:dph") Annotation( "GOC:kmv") Annotation( "GOC:pr") Annotation( "GOC:vw") Annotation( "ISBN:0198506732") Annotation( "PMID:13978319") Annotation( "PMID:27350441") Annotation( "Reactome:R-HSA-5617833.2") "The assembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "GO:0042384") -AnnotationAssertion( "Reactome:R-HSA-5617833.2") -AnnotationAssertion( "ciliogenesis") -AnnotationAssertion( "cilium formation") -AnnotationAssertion( "microtubule-based flagellum assembly") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:mah") "cilium biogenesis") -AnnotationAssertion( "cilium morphogenesis") -AnnotationAssertion(Annotation( "GOC:dph") "cilium organization") -AnnotationAssertion( "GO:0060271") -AnnotationAssertion(rdfs:comment "Note that we deem cilium and microtubule-based flagellum to be equivalent.") -AnnotationAssertion(rdfs:label "cilium assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) -SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) -SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) -SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) -SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) -SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) -SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) -SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) -SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) -SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) -SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) -DisjointClasses( ObjectSomeValuesFrom( )) -DisjointClasses( ObjectSomeValuesFrom( )) -DisjointClasses( ObjectSomeValuesFrom( )) -DisjointClasses( ObjectSomeValuesFrom( )) -DisjointClasses( ObjectSomeValuesFrom( )) -DisjointClasses( ObjectSomeValuesFrom( )) - -# Class: (regulation of oocyte development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") Annotation( "PMID:2394318") "Any process that modulates the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060281") -AnnotationAssertion(rdfs:label "regulation of oocyte development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of oocyte development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that increases the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060282") -AnnotationAssertion(rdfs:label "positive regulation of oocyte development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of oocyte development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that decreases the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060283") -AnnotationAssertion(rdfs:label "negative regulation of oocyte development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of cell development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060284") -AnnotationAssertion(rdfs:label "regulation of cell development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (cilium-dependent cell motility) - -AnnotationAssertion(Annotation( "GOC:cilia") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:krc") Annotation( "GOC:mlg") Annotation( "GOC:mtg_cambridge_2013") "Cell motility due to the motion of one or more eukaryotic cilia. A eukaryotic cilium is a specialized organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole.") -AnnotationAssertion( "GO:0071974") -AnnotationAssertion( "cilium cell motility") -AnnotationAssertion( "microtubule-based flagellar cell motility") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "ciliary cell motility") -AnnotationAssertion( "GO:0060285") -AnnotationAssertion(rdfs:comment "Note that we deem eukaryotic cilia and microtubule-based flagella to be equivalent.") -AnnotationAssertion(rdfs:label "cilium-dependent cell motility") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cilium movement involved in cell motility) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:tb") "Movement of cilia mediated by motor proteins that contributes to the movement of a cell.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060294") -AnnotationAssertion(rdfs:label "cilium movement involved in cell motility") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (regulation of cilium movement involved in cell motility) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the rate frequency or extent of cilium movement involved in ciliary motility.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060295") -AnnotationAssertion(rdfs:label "regulation of cilium movement involved in cell motility") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (regulation of sarcomere organization) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the rate, frequency or extent of myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs.") -AnnotationAssertion(Annotation( "GOC:mah") "regulation of sarcomere organisation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060297") -AnnotationAssertion(rdfs:label "regulation of sarcomere organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of sarcomere organization) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that increases the rate, frequency or extent of myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs.") -AnnotationAssertion(Annotation( "GOC:mah") "positive regulation of sarcomere organisation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060298") -AnnotationAssertion(rdfs:label "positive regulation of sarcomere organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (negative regulation of sarcomere organization) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that decreases the rate, frequency or extent of myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs.") -AnnotationAssertion(Annotation( "GOC:mah") "negative regulation of sarcomere organisation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060299") -AnnotationAssertion(rdfs:label "negative regulation of sarcomere organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (head development) - -AnnotationAssertion(Annotation( "GOC:dph") "The biological process whose specific outcome is the progression of a head from an initial condition to its mature state. The head is the anterior-most division of the body.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060322") -AnnotationAssertion(rdfs:label "head development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (head morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") "The process in which the anatomical structures of the head are generated and organized. The head is the anterior-most division of the body.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060323") -AnnotationAssertion(rdfs:label "head morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (face development) - -AnnotationAssertion(Annotation( "GOC:dph") "The biological process whose specific outcome is the progression of a face from an initial condition to its mature state. The face is the ventral division of the head.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060324") -AnnotationAssertion(rdfs:label "face development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (face morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") "The process in which the anatomical structures of the face are generated and organized. The face is the ventral division of the head.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060325") -AnnotationAssertion(rdfs:label "face morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cell chemotaxis) - -AnnotationAssertion(Annotation( "GOC:dph") "The directed movement of a motile cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060326") -AnnotationAssertion(rdfs:label "cell chemotaxis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (regulation of cellular localization) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the frequency, rate or extent of a process in which a cell, a substance, or a cellular entity is transported to, or maintained in a specific location within or in the membrane of a cell.") -AnnotationAssertion(Annotation( "GOC:mah") "regulation of cellular localisation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060341") -AnnotationAssertion(rdfs:label "regulation of cellular localization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (trabecula formation) - -AnnotationAssertion(Annotation( "GOC:dph") "The process of creating a trabecula in an organ. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue.") -AnnotationAssertion(Annotation( "GOC:dph") "trabeculation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") "trabecula biogenesis") -AnnotationAssertion( "GO:0060343") -AnnotationAssertion(rdfs:label "trabecula formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (liver trabecula formation) - -AnnotationAssertion(Annotation( "GOC:dph") "The process of creating a trabecula in the liver. A trabecula is a tissue element in the form of a small beam, strut or rod.") -AnnotationAssertion(Annotation( "GOC:dph") "liver trabeculation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "liver trabecula biogenesis") -AnnotationAssertion( "GO:0060344") -AnnotationAssertion(rdfs:label "liver trabecula formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (spleen trabecula formation) - -AnnotationAssertion(Annotation( "GOC:dph") "The process of creating a trabecula in the spleen. A trabecula is a tissue element in the form of a small beam, strut or rod.") -AnnotationAssertion(Annotation( "GOC:dph") "spleen trabeculation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") "spleen trabecula biogenesis") -AnnotationAssertion( "GO:0060345") -AnnotationAssertion(rdfs:label "spleen trabecula formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (bone trabecula formation) - -AnnotationAssertion(Annotation( "GOC:dph") "The process of creating a trabecula in the bone. A trabecula is a tissue element in the form of a small beam, strut or rod.") -AnnotationAssertion(Annotation( "GOC:dph") "bone trabeculation") -AnnotationAssertion(Annotation( "GOC:dph") "skeletal trabecula formation") -AnnotationAssertion(Annotation( "GOC:dph") "skeletal trabeculation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") "bone trabecula biogenesis") -AnnotationAssertion(Annotation( "GOC:dph") "skeletal trabecula biogenesis") -AnnotationAssertion( "GO:0060346") -AnnotationAssertion(rdfs:label "bone trabecula formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (heart trabecula formation) - -AnnotationAssertion(Annotation( "GOC:dph") "The process of creating a trabecula in the heart. A trabecula is a tissue element in the form of a small beam, strut or rod.") -AnnotationAssertion(Annotation( "GOC:dph") "cardiac trabecula formation") -AnnotationAssertion(Annotation( "GOC:dph") "cardiac trabeculation") -AnnotationAssertion(Annotation( "GOC:dph") "heart trabeculation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") "heart trabecula biogenesis") -AnnotationAssertion( "GO:0060347") -AnnotationAssertion(rdfs:label "heart trabecula formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (bone development) - -AnnotationAssertion(Annotation( "GOC:dph") "The process whose specific outcome is the progression of bone over time, from its formation to the mature structure. Bone is the hard skeletal connective tissue consisting of both mineral and cellular components.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060348") -AnnotationAssertion(rdfs:label "bone development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (bone morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") "The process in which bones are generated and organized.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060349") -AnnotationAssertion(rdfs:label "bone morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (endochondral bone morphogenesis) AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:11680679") "The process in which bones are generated and organized as a result of the conversion of initial cartilaginous anlage into bone.") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0060350") AnnotationAssertion(rdfs:label "endochondral bone morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cartilage development involved in endochondral bone morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") "The process whose specific outcome is the progression of the cartilage that will provide a scaffold for mineralization of endochondral bones.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060351") -AnnotationAssertion(rdfs:label "cartilage development involved in endochondral bone morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (response to ammonium ion) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000071") Annotation( "PMID:23509267") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ammonium stimulus.") -AnnotationAssertion( "GO:1903717") -AnnotationAssertion( "response to ammonia") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060359") -AnnotationAssertion(rdfs:label "response to ammonium ion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (flight) @@ -97631,263 +26971,6 @@ AnnotationAssertion( "flight") SubClassOf( ) -# Class: (cranial suture morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:pr") Annotation( "GOC:sl") "The process in which any suture between cranial bones is generated and organized.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060363") -AnnotationAssertion(rdfs:label "cranial suture morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (frontal suture morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:sl") "The process in which the frontal suture is generated and organized.") -AnnotationAssertion( "interfrontal suture morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060364") -AnnotationAssertion(rdfs:label "frontal suture morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (coronal suture morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:sl") "The process in which the coronal suture is generated and organized.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060365") -AnnotationAssertion(rdfs:label "coronal suture morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (lambdoid suture morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:sl") "The process in which the lambdoid suture is generated and organized.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060366") -AnnotationAssertion(rdfs:label "lambdoid suture morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (sagittal suture morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:sl") "The process in which the sagittal suture is generated and organized.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060367") -AnnotationAssertion(rdfs:label "sagittal suture morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (cardiac muscle cell myoblast differentiation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "The process in which a relatively unspecialized cell acquires specialized features of a cardiac myoblast. A cardiac myoblast is a precursor cell that has been committed to a cardiac muscle cell fate but retains the ability to divide and proliferate throughout life.") -AnnotationAssertion(Annotation( "GOC:mtg_heart") "myocardial precursor cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "cardiac myoblast differentiation") -AnnotationAssertion( "GO:0060379") -AnnotationAssertion(rdfs:label "cardiac muscle cell myoblast differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (axonemal microtubule depolymerization) - -AnnotationAssertion(Annotation( "GOC:cilia") Annotation( "GOC:dph") Annotation( "GOC:krc") Annotation( "GOC:tb") "The removal of tubulin heterodimers from one or both ends of an axonemal microtubule. An axonemal microtubule is a microtubule in the axoneme of a cilium or flagellum; an axoneme contains nine modified doublet microtubules surrounding a pair of single microtubules.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060404") -AnnotationAssertion(rdfs:label "axonemal microtubule depolymerization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of penile erection) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the rate, frequency or extent of penile erection. Penile erection is the hardening, enlarging and rising of the penis which often occurs in the sexually aroused male and enables sexual intercourse. Achieved by increased inflow of blood into the vessels of erectile tissue, and decreased outflow.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060405") -AnnotationAssertion(rdfs:label "regulation of penile erection") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of penile erection) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that increases the rate, frequency or extent of penile erection. Penile erection is the hardening, enlarging and rising of the penis which often occurs in the sexually aroused male and enables sexual intercourse. Achieved by increased inflow of blood into the vessels of erectile tissue, and decreased outflow.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060406") -AnnotationAssertion(rdfs:label "positive regulation of penile erection") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of penile erection) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that stops, prevents, or reduces the rate, frequency or extent of penile erection. Penile erection is the hardening, enlarging and rising of the penis which often occurs in the sexually aroused male and enables sexual intercourse. Achieved by increased inflow of blood into the vessels of erectile tissue, and decreased outflow.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060407") -AnnotationAssertion(rdfs:label "negative regulation of penile erection") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of acetylcholine metabolic process) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the rate, frequency or extent of the chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060408") -AnnotationAssertion(rdfs:label "regulation of acetylcholine metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of acetylcholine metabolic process) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that increases the rate, frequency or extent of the chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060409") -AnnotationAssertion(rdfs:label "positive regulation of acetylcholine metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (negative regulation of acetylcholine metabolic process) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that decreases the rate, frequency or extent of the chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060410") -AnnotationAssertion(rdfs:label "negative regulation of acetylcholine metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (cardiac septum morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_heart") "The process in which the anatomical structure of a cardiac septum is generated and organized. A cardiac septum is a partition that separates parts of the heart.") -AnnotationAssertion( "GO:0003280") -AnnotationAssertion( "heart septum morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060411") -AnnotationAssertion(rdfs:label "cardiac septum morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (ventricular septum morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") "The developmental process in which a ventricular septum is generated and organized. A ventricular septum is an anatomical structure that separates the lower chambers (ventricles) of the heart from one another.") -AnnotationAssertion(Annotation( "GOC:dph") "interventricular septum morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060412") -AnnotationAssertion(rdfs:label "ventricular septum morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (atrial septum morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_heart") "The developmental process in which atrial septum is generated and organized. The atrial septum separates the upper chambers (the atria) of the heart from one another.") -AnnotationAssertion( "GO:0003287") -AnnotationAssertion(Annotation( "GOC:dph") "interatrial septum morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060413") -AnnotationAssertion(rdfs:label "atrial septum morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (aorta smooth muscle tissue morphogenesis) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "Wikipedia:Aorta") "The process in which the structure of the smooth muscle tissue surrounding the aorta is generated and organized. An aorta is an artery that carries blood from the heart to other parts of the body.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060414") -AnnotationAssertion(rdfs:label "aorta smooth muscle tissue morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (muscle tissue morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") "The process in which the anatomical structures of muscle tissue are generated and organized. Muscle tissue consists of a set of cells that are part of an organ and carry out a contractive function.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060415") -AnnotationAssertion(rdfs:label "muscle tissue morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (heart growth) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "The increase in size or mass of the heart.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060419") -AnnotationAssertion(rdfs:label "heart growth") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (regulation of heart growth) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060420") -AnnotationAssertion(rdfs:label "regulation of heart growth") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of heart growth) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that increases the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060421") -AnnotationAssertion(rdfs:label "positive regulation of heart growth") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (lung morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") "The process in which the anatomical structures of the lung are generated and organized.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060425") -AnnotationAssertion(rdfs:label "lung morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (lung vasculature development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_lung") "The biological process whose specific outcome is the progression of a lung vasculature from an initial condition to its mature state. This process begins with the formation of the lung vasculature and ends with the mature structure. The lung vasculature is composed of the tubule structures that carry blood or lymph in the lungs.") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_lung") "pulmonary vasculature development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060426") -AnnotationAssertion(rdfs:label "lung vasculature development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (lung connective tissue development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_lung") "The biological process whose specific outcome is the progression of lung connective tissue from an initial condition to its mature state. This process begins with the formation of lung connective tissue and ends with the mature structure. The lung connective tissue is a material made up of fibers forming a framework and support structure for the lungs.") -AnnotationAssertion( "pulmonary connective tissue development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060427") -AnnotationAssertion(rdfs:label "lung connective tissue development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (lung epithelium development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_lung") "The biological process whose specific outcome is the progression of the lung epithelium from an initial condition to its mature state. This process begins with the formation of lung epithelium and ends with the mature structure. The lung epithelium is the specialized epithelium that lines the inside of the lung.") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_lung") "pulmonary epithelium development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060428") -AnnotationAssertion(rdfs:label "lung epithelium development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (epithelium development) AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_lung") "The process whose specific outcome is the progression of an epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure.") @@ -97895,751 +26978,8 @@ AnnotationAssertion( "GO:0060429") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "epithelium development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (lung saccule development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_lung") "The biological process whose specific outcome is the progression of a lung saccule from an initial condition to its mature state. The lung saccule is the primitive gas exchange portion of the lung composed of type I and type II cells.") -AnnotationAssertion(Annotation( "GOC:dph") "lung saccular development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060430") -AnnotationAssertion(rdfs:label "lung saccule development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (primary lung bud formation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_lung") "The morphogenetic process in which the foregut region specified to become the lung forms the initial left and right buds.") -AnnotationAssertion(Annotation( "GOC:dph") "lung formation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060431") -AnnotationAssertion(rdfs:label "primary lung bud formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (bronchus development) - -AnnotationAssertion(Annotation( "GOC:dph") "The biological process whose specific outcome is the progression of a bronchus from an initial condition to its mature state. This process begins with the formation of the bronchus and ends with the mature structure. The bronchus is the portion of the airway that connects to the lungs.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060433") -AnnotationAssertion(rdfs:label "bronchus development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (bronchus morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") "The process in which the bronchus is generated and organized. The bronchus is the portion of the airway that connects to the lungs.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060434") -AnnotationAssertion(rdfs:label "bronchus morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (bronchiole development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_lung") "The biological process whose specific outcome is the progression of a bronchiole from an initial condition to its mature state. This process begins with the formation of the bronchiole and ends with the mature structure. A bronchiole is the first airway branch that no longer contains cartilage; it is a branch of the bronchi.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060435") -AnnotationAssertion(rdfs:label "bronchiole development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (bronchiole morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") "The process in which a bronchiole is generated and organized. A bronchiole is the first airway branch that no longer contains cartilage; it is a branch of the bronchi.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060436") -AnnotationAssertion(rdfs:label "bronchiole morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (lung growth) - -AnnotationAssertion(Annotation( "GOC:dph") "The increase in size or mass of a lung. In all air-breathing vertebrates the lungs are developed from the ventral wall of the oesophagus as a pouch which divides into two sacs. In amphibians and many reptiles the lungs retain very nearly this primitive sac-like character, but in the higher forms the connection with the esophagus becomes elongated into the windpipe and the inner walls of the sacs become more and more divided, until, in the mammals, the air spaces become minutely divided into tubes ending in small air cells, in the walls of which the blood circulates in a fine network of capillaries. In mammals the lungs are more or less divided into lobes, and each lung occupies a separate cavity in the thorax.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060437") -AnnotationAssertion(rdfs:label "lung growth") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (trachea development) - -AnnotationAssertion(Annotation( "GOC:dph") "The process whose specific outcome is the progression of a trachea over time, from its formation to the mature structure. The trachea is the portion of the airway that attaches to the bronchi as it branches.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060438") -AnnotationAssertion(rdfs:label "trachea development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (trachea morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") "The process in which a trachea is generated and organized. The trachea is the portion of the airway that attaches to the bronchi as it branches.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060439") -AnnotationAssertion(rdfs:label "trachea morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (trachea formation) - -AnnotationAssertion(Annotation( "GOC:dph") "The process pertaining to the initial formation of a trachea from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the trachea is recognizable. The trachea is the portion of the airway that attaches to the bronchi as it branches.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060440") -AnnotationAssertion(rdfs:label "trachea formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (epithelial tube branching involved in lung morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_lung") "The process in which a highly ordered sequence of patterning events generates the branched epithelial tubes of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units.") -AnnotationAssertion(Annotation( "GOC:dph") "lung branching morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060441") -AnnotationAssertion(rdfs:label "epithelial tube branching involved in lung morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (branching involved in prostate gland morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") "The process in which the branching structure of the prostate gland is generated and organized. A branch is a division or offshoot from a main stem.") -AnnotationAssertion(Annotation( "GOC:dph") "prostate gland branching morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") "prostate branching") -AnnotationAssertion( "GO:0060442") -AnnotationAssertion(rdfs:label "branching involved in prostate gland morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (mammary gland morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") "The process in which anatomical structures of the mammary gland are generated and organized. Morphogenesis refers to the creation of shape. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060443") -AnnotationAssertion(rdfs:label "mammary gland morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (branching involved in mammary gland duct morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") "The process in which the branching structure of the mammary gland duct is generated and organized. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk.") -AnnotationAssertion(Annotation( "GOC:dph") "mammary gland branching morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060444") -AnnotationAssertion(rdfs:label "branching involved in mammary gland duct morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (branching involved in salivary gland morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") "The process in which the branching structure of the salivary gland is generated and organized.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060445") -AnnotationAssertion(rdfs:label "branching involved in salivary gland morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (branching involved in open tracheal system development) - -AnnotationAssertion(Annotation( "GOC:dph") "The process in which the anatomical structures of branches in the open tracheal system are generated and organized.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060446") -AnnotationAssertion(rdfs:label "branching involved in open tracheal system development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of hindgut contraction) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that increases the frequency, rate or extent of muscle contraction of the hindgut, the posterior part of the alimentary canal, including the rectum, and the large intestine.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060450") -AnnotationAssertion(rdfs:label "positive regulation of hindgut contraction") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of hindgut contraction) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that decreases the frequency, rate or extent of muscle contraction of the hindgut, the posterior part of the alimentary canal, including the rectum, and the large intestine.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060451") -AnnotationAssertion(rdfs:label "negative regulation of hindgut contraction") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of cardiac muscle contraction) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that increases the frequency, rate or extent of cardiac muscle contraction.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060452") -AnnotationAssertion(rdfs:label "positive regulation of cardiac muscle contraction") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of gastric acid secretion) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the rate frequency or extent of gastric secretion. Gastric secretion is the regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060453") -AnnotationAssertion(rdfs:label "regulation of gastric acid secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of gastric acid secretion) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that increases the rate frequency or extent of gastric secretion. Gastric secretion is the regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060454") -AnnotationAssertion(rdfs:label "positive regulation of gastric acid secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of gastric acid secretion) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that decreases the rate frequency or extent of gastric secretion. Gastric secretion is the regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060455") -AnnotationAssertion(rdfs:label "negative regulation of gastric acid secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of digestive system process) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that increases the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060456") -AnnotationAssertion(rdfs:label "positive regulation of digestive system process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of digestive system process) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that decreases the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060457") -AnnotationAssertion(rdfs:label "negative regulation of digestive system process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (right lung development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_lung") "The biological process whose specific outcome is the progression of a right lung from an initial condition to its mature state. This process begins with the formation of the right lung and ends with the mature structure. The right lung is the lung which is on the right side of the anterior posterior axis looking from a dorsal to ventral aspect.") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_lung") "right pulmonary development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060458") -AnnotationAssertion(rdfs:label "right lung development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (left lung development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_lung") "The biological process whose specific outcome is the progression of a left lung from an initial condition to its mature state. This process begins with the formation of the left lung and ends with the mature structure. The left lung is the lung which is on the left side of the anterior posterior axis looking from a dorsal to ventral aspect.") -AnnotationAssertion(Annotation( "GOC:dph") "left pulmonary development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060459") -AnnotationAssertion(rdfs:label "left lung development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (left lung morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") "The process in which anatomical structures of the left lung are generated and organized.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060460") -AnnotationAssertion(rdfs:label "left lung morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (right lung morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_lung") "The process in which anatomical structures of the right lung are generated and organized.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060461") -AnnotationAssertion(rdfs:label "right lung morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (lung lobe development) - -AnnotationAssertion(Annotation( "GOC:dph") "The biological process whose specific outcome is the progression of a lung lobe from an initial condition to its mature state. This process begins with the formation of a lung lobe by branching morphogenesis and ends with the mature structure. A lung lobe is one of the rounded projections that compose the lung.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060462") -AnnotationAssertion(rdfs:label "lung lobe development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (lung lobe morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") "The process in which the anatomical structures of a lung lobe are generated and organized. A lung lobe is a projection that extends from the lung.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060463") -AnnotationAssertion(rdfs:label "lung lobe morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (lung lobe formation) - -AnnotationAssertion(Annotation( "GOC:dph") "The developmental process pertaining to the initial formation of a lung lobe from unspecified parts. This process begins with the specific processes that contribute to the appearance of the lobe and ends when the structural rudiment is recognizable. A lung lobe is a projection that extends from the lung.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060464") -AnnotationAssertion(rdfs:label "lung lobe formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (pharynx development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:rk") "The biological process whose specific outcome is the progression of a pharynx from an initial condition to its mature state. The pharynx is the part of the digestive system immediately posterior to the mouth.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "pharyngeal development") -AnnotationAssertion( "GO:0060465") -AnnotationAssertion(rdfs:label "pharynx development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (negative regulation of fertilization) - -AnnotationAssertion(Annotation( "GOC:dph") "Any process that decreases the rate, frequency or extent of fertilization. Fertilization is the union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy).") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060467") -AnnotationAssertion(rdfs:label "negative regulation of fertilization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (prevention of polyspermy) - -AnnotationAssertion(Annotation( "GOC:dph") "The negative regulation of fertilization process that takes place as part of egg activation, ensuring that only a single sperm fertilizes the egg.") -AnnotationAssertion(Annotation( "GOC:dph") "negative regulation of fertilization involved in egg activation") -AnnotationAssertion(Annotation( "GOC:dph") "polyspermy block") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060468") -AnnotationAssertion(rdfs:label "prevention of polyspermy") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of flagellated sperm motility involved in capacitation) - -AnnotationAssertion(Annotation( "GOC:cilia") Annotation( "GOC:dph") Annotation( "GOC:krc") "The process in which the controlled movement of a flagellated sperm cell is initiated as part of the process required for flagellated sperm to reach fertilization competence.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "positive regulation of sperm motility involved in capacitation") -AnnotationAssertion( "GO:0060474") -AnnotationAssertion(rdfs:label "positive regulation of flagellated sperm motility involved in capacitation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (lung cell differentiation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_lung") "The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features of a mature cell found in the lung. Differentiation includes the processes involved in commitment of a cell to a specific fate.") -AnnotationAssertion(Annotation( "GOC:dph") "pulmonary cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060479") -AnnotationAssertion(rdfs:label "lung cell differentiation") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (lung goblet cell differentiation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_lung") "The process in which a relatively unspecialized cell acquires specialized features of a lung goblet cell. A goblet cell is a cell of the epithelial lining that produces and secretes mucins.") -AnnotationAssertion( "pulmonary goblet cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060480") -AnnotationAssertion(rdfs:label "lung goblet cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (lobar bronchus epithelium development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_lung") "The biological process whose specific outcome is the progression of a lobar bronchus epithelium from an initial condition to its mature state. This process begins with the formation of the lobar bronchus epithelium and ends with the mature structure. The lobar bronchus epithelium is the tissue made up of epithelial cells that lines the inside of the lobar bronchus.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060481") -AnnotationAssertion(rdfs:label "lobar bronchus epithelium development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (lobar bronchus development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_lung") "The biological process whose specific outcome is the progression of a lobar bronchus from an initial condition to its mature state. This process begins with the formation of the lobar bronchus and ends with the mature structure. The lobar bronchus is the major airway within the respiratory tree that starts by division of the principal bronchi on both sides and ends at the point of its own subdivision into tertiary or segmental bronchi.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060482") -AnnotationAssertion(rdfs:label "lobar bronchus development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (lobar bronchus mesenchyme development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_lung") "The biological process whose specific outcome is the progression of a lobar bronchus mesenchyme from an initial condition to its mature state. This process begins with the formation of the lobar bronchus mesenchyme and ends with the mature structure. The lobar bronchus mesenchyme is the mass of tissue composed of mesenchymal cells in the lobar bronchus.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060483") -AnnotationAssertion(rdfs:label "lobar bronchus mesenchyme development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (lung-associated mesenchyme development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_lung") "The biological process whose specific outcome is the progression of a lung-associated mesenchyme from an initial condition to its mature state. This process begins with the formation of lung-associated mesenchyme and ends with the mature structure. Lung-associated mesenchyme is the tissue made up of loosely connected mesenchymal cells in the lung.") -AnnotationAssertion(Annotation( "GOC:dph") "lung mesenchyme development") -AnnotationAssertion(Annotation( "GOC:dph") "pulmonary mesenchyme development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060484") -AnnotationAssertion(rdfs:label "lung-associated mesenchyme development") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (mesenchyme development) - -AnnotationAssertion(Annotation( "GOC:dph") "The process whose specific outcome is the progression of a mesenchymal tissue over time, from its formation to the mature structure. A mesenchymal tissue is made up of loosely packed stellate cells.") -AnnotationAssertion(Annotation( "GOC:dph") "mesenchymal development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060485") -AnnotationAssertion(rdfs:label "mesenchyme development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (club cell differentiation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_lung") Annotation( "PMID:28144783") "The process in which a relatively unspecialized cell acquires specialized features of a club cell. A club cell is an unciliated epithelial cell found in the respiratory and terminal bronchioles.") -AnnotationAssertion(Annotation( "PMID:28144783") "Clara cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060486") -AnnotationAssertion(rdfs:label "club cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (lung epithelial cell differentiation) - -AnnotationAssertion(Annotation( "GOC:dph") "The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell that contributes to the epithelium of the lung.") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") "pulmonary epithelial cell differentiation") -AnnotationAssertion( "GO:0060487") -AnnotationAssertion(rdfs:label "lung epithelial cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (lateral sprouting involved in lung morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_lung") "The process in which a branch forms along the side of the lung epithelial tube.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060490") -AnnotationAssertion(rdfs:label "lateral sprouting involved in lung morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of cell projection assembly) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the rate, frequency, or extent of cell projection assembly.") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "regulation of cell projection formation") -AnnotationAssertion( "GO:0060491") -AnnotationAssertion(rdfs:label "regulation of cell projection assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (cell-cell signaling involved in lung development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_lung") "Any process that mediates the transfer of information from one cell to another and contributes to the progression of the lung, from its initial state to the mature structure.") -AnnotationAssertion(Annotation( "GOC:mah") "cell-cell signalling involved in lung development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060495") -AnnotationAssertion(rdfs:label "cell-cell signaling involved in lung development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of epithelial cell proliferation involved in lung morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") "Any process that increases the rate or frequency of epithelial cell proliferation that results in the lung attaining its shape.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060501") -AnnotationAssertion(rdfs:label "positive regulation of epithelial cell proliferation involved in lung morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (epithelial cell proliferation involved in lung morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") "The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population that contributes to the shaping of the lung.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060502") -AnnotationAssertion(rdfs:label "epithelial cell proliferation involved in lung morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (type I pneumocyte differentiation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_lung") Annotation( "ISBN:0721662544") "The process in which a relatively unspecialized cell acquires specialized features of a type I pneumocyte. A type I pneumocyte is a flattened cell with greatly attenuated cytoplasm and a paucity of organelles.") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "ISBN:0721662544") "membranous pneumocyte differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "ISBN:0721662544") "small alveolar cell differentiation") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "ISBN:0721662544") "squamous alveolar cell differentiation") -AnnotationAssertion( "GO:0060509") -AnnotationAssertion(rdfs:label "type I pneumocyte differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (type II pneumocyte differentiation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_lung") Annotation( "ISBN:0721662544") "The process in which a relatively unspecialized cell acquires specialized features of a type II pneumocyte. A type II pneumocyte is a surfactant secreting cell that contains abundant cytoplasm containing numerous lipid-rich multilamellar bodies.") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "ISBN:0721662544") "great alveolar cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "ISBN:0721662544") "granular pneumocyte differentiation") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "ISBN:0721662544") "large alveolar cell differentiation") -AnnotationAssertion( "GO:0060510") -AnnotationAssertion(rdfs:label "type II pneumocyte differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (prostate gland morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:18977204") "The process in which the anatomical structures of a prostate gland are generated and organized.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060512") -AnnotationAssertion(rdfs:label "prostate gland morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (prostatic bud formation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:18977204") "The morphogenetic process in which a region of the fetal urogenital sinus epithelium is specified to become the prostate, resulting in prostate bud outgrowth.") -AnnotationAssertion(Annotation( "GOC:dph") "primary prostate bud formation") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:11401393") "prostate ductal budding") -AnnotationAssertion(Annotation( "GOC:dph") "prostate gland formation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060513") -AnnotationAssertion(rdfs:label "prostatic bud formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (prostate glandular acinus development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:18977204") "The progression of a glandular acinus of the prostate gland over time, from its initial formation to the mature structure. The glandular acini are the saclike structures of the gland.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060525") -AnnotationAssertion(rdfs:label "prostate glandular acinus development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (prostate glandular acinus morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") "The process in which the prostate glandular acini are generated and organized. The glandular acini are the saclike structures of the gland.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060526") -AnnotationAssertion(rdfs:label "prostate glandular acinus morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (smooth muscle cell differentiation involved in prostate glandular acinus development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:18977204") "The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell of the prostate glandular acinus.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060530") -AnnotationAssertion(rdfs:label "smooth muscle cell differentiation involved in prostate glandular acinus development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (neuroendocrine cell differentiation involved in prostate gland acinus development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:18977204") "The process in which relatively unspecialized cells acquires specialized structural and functions of a neuroendocrine cell of the prostate gland acinus.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060531") -AnnotationAssertion(rdfs:label "neuroendocrine cell differentiation involved in prostate gland acinus development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (bronchus cartilage development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_lung") "The process whose specific outcome is the progression of lung cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-04-10T08:12:06Z") -AnnotationAssertion( "pulmonary cartilage development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060532") -AnnotationAssertion(rdfs:label "bronchus cartilage development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (bronchus cartilage morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") "The process in which the bronchus cartilage is generated and organized. The bronchus cartilage is the connective tissue of the portion of the airway that connects to the lungs.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-04-10T08:47:41Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060533") -AnnotationAssertion(rdfs:label "bronchus cartilage morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (trachea cartilage development) - -AnnotationAssertion(Annotation( "GOC:dph") "The process whose specific outcome is the progression of the tracheal cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-04-10T09:00:18Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060534") -AnnotationAssertion(rdfs:label "trachea cartilage development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (trachea cartilage morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") "The process in which the anatomical structures of cartilage in the trachea are generated and organized.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-04-10T09:07:48Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060535") -AnnotationAssertion(rdfs:label "trachea cartilage morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cartilage morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") "The process in which the anatomical structures of cartilage are generated and organized.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-04-10T09:13:27Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060536") -AnnotationAssertion(rdfs:label "cartilage morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (muscle tissue development) - -AnnotationAssertion(Annotation( "GOC:dph") "The progression of muscle tissue over time, from its initial formation to its mature state. Muscle tissue is a contractile tissue made up of actin and myosin fibers.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-04-10T08:05:37Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060537") -AnnotationAssertion(rdfs:label "muscle tissue development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (skeletal muscle organ development) - -AnnotationAssertion(Annotation( "GOC:dph") "The progression of a skeletal muscle organ over time from its initial formation to its mature state. A skeletal muscle organ includes the skeletal muscle tissue and its associated connective tissue.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-04-10T08:25:12Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060538") -AnnotationAssertion(rdfs:label "skeletal muscle organ development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (diaphragm development) - -AnnotationAssertion(Annotation( "GOC:dph") "The progression of the diaphragm over time from its initial formation to the mature structure. The diaphragm is a skeletal muscle that is responsible for contraction and expansion of the lungs.") -AnnotationAssertion( ) -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-04-10T08:44:56Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060539") -AnnotationAssertion(rdfs:label "diaphragm development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) -DisjointClasses( ObjectSomeValuesFrom( )) - -# Class: (diaphragm morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") "The process in which the anatomical structures of the diaphragm are generated and organized.") -AnnotationAssertion( ) -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-04-10T08:47:51Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060540") -AnnotationAssertion(rdfs:label "diaphragm morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) -DisjointClasses( ObjectSomeValuesFrom( )) - -# Class: (respiratory system development) - -AnnotationAssertion(Annotation( "GOC:dph") "The progression of the respiratory system over time from its formation to its mature structure. The respiratory system carries out respiratory gaseous exchange.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-04-10T08:55:42Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060541") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "respiratory system development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (developmental growth involved in morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") "The increase in size or mass of an anatomical structure that contributes to the structure attaining its shape.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-04-28T08:42:53Z") -AnnotationAssertion(Annotation( "GOC:dph") "differential growth") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060560") -AnnotationAssertion(rdfs:label "developmental growth involved in morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (apoptotic process involved in morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_apoptosis") "Any apoptotic process that contributes to the shaping of an anatomical structure.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-04-28T09:17:27Z") -AnnotationAssertion( "apoptosis involved in morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "apoptosis involved in development") -AnnotationAssertion(Annotation( "GOC:dph") "morphogenetic apoptosis") -AnnotationAssertion( "GO:0060561") -AnnotationAssertion(rdfs:label "apoptotic process involved in morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - # Class: (epithelial tube morphogenesis) AnnotationAssertion(Annotation( "GOC:dph") "The process in which the anatomical structures of a tube are generated and organized from an epithelium. Epithelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues, with tube shape and organization varying from the single-celled excretory organ in Caenorhabditis elegans to the branching trees of the mammalian kidney and insect tracheal system.") @@ -98648,232 +26988,9 @@ AnnotationAssertion( AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0060562") AnnotationAssertion(rdfs:label "epithelial tube morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) -# Class: (neuroepithelial cell differentiation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "The process in which epiblast cells acquire specialized features of neuroepithelial cells.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-04-29T01:50:05Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060563") -AnnotationAssertion(rdfs:label "neuroepithelial cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of peptide hormone processing) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the rate, frequency or extent of peptide hormone processing. Peptide hormone processing is the generation of a mature peptide hormone by posttranslational processing of a prohormone.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-04-29T03:16:05Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060568") -AnnotationAssertion(rdfs:label "regulation of peptide hormone processing") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of peptide hormone processing) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that increases the rate, frequency or extent of peptide hormone processing. Peptide hormone processing is the generation of a mature peptide hormone by posttranslational processing of a prohormone.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-04-29T03:22:05Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060569") -AnnotationAssertion(rdfs:label "positive regulation of peptide hormone processing") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of peptide hormone processing) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that decreases the rate, frequency or extent of peptide hormone processing. Peptide hormone processing is the generation of a mature peptide hormone by posttranslational processing of a prohormone.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-04-29T03:24:55Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060570") -AnnotationAssertion(rdfs:label "negative regulation of peptide hormone processing") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (morphogenesis of an epithelial fold) - -AnnotationAssertion(Annotation( "GOC:dph") "The morphogenetic process in which an epithelial sheet bends along a linear axis.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-04-30T09:27:17Z") -AnnotationAssertion(Annotation( "GOC:dph") "epithelial folding") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") "folding of an epithelial sheet") -AnnotationAssertion( "GO:0060571") -AnnotationAssertion(rdfs:label "morphogenesis of an epithelial fold") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (morphogenesis of an epithelial bud) - -AnnotationAssertion(Annotation( "GOC:dph") "The morphogenetic process in which a bud forms from an epithelial sheet. A bud is a protrusion that forms form the sheet by localized folding.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-04-30T09:38:35Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060572") -AnnotationAssertion(rdfs:label "morphogenesis of an epithelial bud") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (intestinal epithelial cell maturation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:18824147") "The developmental process, independent of morphogenetic (shape) change, that is required for a columna/cuboidal epithelial cell of the intestine to attain its fully functional state. A columnar/cuboidal epithelial cell of the intestine mature as they migrate from the intestinal crypt to the villus.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-05-06T08:10:41Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060574") -AnnotationAssertion(rdfs:label "intestinal epithelial cell maturation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (intestinal epithelial cell differentiation) - -AnnotationAssertion(Annotation( "GOC:dph") "The process in which a relatively unspecialized cell acquires specialized features of a columnar/cuboidal epithelial cell of the intestine.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-05-06T08:17:56Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060575") -AnnotationAssertion(rdfs:label "intestinal epithelial cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (intestinal epithelial cell development) - -AnnotationAssertion(Annotation( "GOC:dph") "The process whose specific outcome is the progression of a columnar/cuboidal epithelial cell of the intestine over time, from its formation to the mature structure.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-05-06T08:20:24Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060576") -AnnotationAssertion(rdfs:label "intestinal epithelial cell development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (pulmonary vein morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") "The process in which the anatomical structure of the pulmonary venous blood vessels are generated and organized. Pulmonary veins are blood vessels that transport blood from the lungs to the heart.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-05-06T08:44:04Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") "pulmonary venous blood vessel morphogenesis") -AnnotationAssertion( "GO:0060577") -AnnotationAssertion(rdfs:label "pulmonary vein morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (superior vena cava morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") "The process in which the anatomical structure of superior vena cava generated and organized. The superior vena cava is a blood vessel that transports blood from the upper body to the heart.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-05-06T08:47:21Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060578") -AnnotationAssertion(rdfs:label "superior vena cava morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (cell fate commitment involved in pattern specification) - -AnnotationAssertion(Annotation( "GOC:dph") "The commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells within a field of cells that will exhibit a certain pattern of differentiation. Positional information is established through protein signals that emanate from a localized source within a developmental field resulting in specification of a cell type. Those signals are then interpreted in a cell-autonomous manner resulting in the determination of the cell type.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-05-07T12:40:55Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060581") -AnnotationAssertion(rdfs:label "cell fate commitment involved in pattern specification") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (multicellular organismal-level iron ion homeostasis) - -AnnotationAssertion(Annotation( "PMID:31431773") "A chemical homeostatic process involved in the maintenance of a steady state level of iron within extracellular body fluids, such as blood, xylem or phloem, of a multicellular organism. This is distinct from maintenance of cellular homeostasis, which occurs within a cell.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/24554"^^xsd:anyURI) -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-05-08T02:18:21Z") -AnnotationAssertion( "multicellular organismal iron ion homeostasis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060586") -AnnotationAssertion(rdfs:label "multicellular organismal-level iron ion homeostasis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (chondroblast differentiation) - -AnnotationAssertion(Annotation( "GOC:dph") "The process in which a mesenchymal cell, acquires specialized structural and/or functional features of a chondroblast. Differentiation includes the processes involved in commitment of a cell to a chondroblast fate. A chondroblast is a precursor cell to chondrocytes.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-05-11T07:47:36Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") "chondrocyte progenitor cell differentiation") -AnnotationAssertion( "GO:0060591") -AnnotationAssertion(rdfs:label "chondroblast differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (mammary gland formation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:16168142") Annotation( "PMID:17120154") "The process pertaining to the initial formation of the mammary gland from unspecified parts. The process begins with formation of the mammary line and ends when the solid mammary bud invades the primary mammary mesenchyme.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-05-13T08:47:52Z") -AnnotationAssertion(Annotation( "GOC:dph") "mammary line formation") -AnnotationAssertion(Annotation( "GOC:dph") "mammary placode formation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") "mammary bud formation") -AnnotationAssertion(Annotation( "GOC:dph") "mammary sprout formation") -AnnotationAssertion( "GO:0060592") -AnnotationAssertion(rdfs:label "mammary gland formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (mammary placode formation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:16168142") "The developmental process in which the mammary placode forms. The mammary placode is a transient lens shaped structure that will give rise to the mammary bud proper.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-05-13T11:55:20Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060596") -AnnotationAssertion(rdfs:label "mammary placode formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (lateral sprouting involved in mammary gland duct morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:17120154") "The process in which a branch forms along the side of a mammary duct.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-05-13T12:38:06Z") -AnnotationAssertion(Annotation( "GOC:dph") "mammary gland duct secondary branching") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060599") -AnnotationAssertion(rdfs:label "lateral sprouting involved in mammary gland duct morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (lateral sprouting from an epithelium) - -AnnotationAssertion(Annotation( "GOC:dph") "The process in which a branch forms along the side of an epithelium.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-05-14T02:33:01Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060601") -AnnotationAssertion(rdfs:label "lateral sprouting from an epithelium") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (mammary gland duct morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:17120154") "The process in which anatomical structures of the mammary ducts are generated and organized. Mammary ducts are epithelial tubes that transport milk.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-05-15T09:22:25Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060603") -AnnotationAssertion(rdfs:label "mammary gland duct morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (tube closure) AnnotationAssertion(Annotation( "GOC:dph") "Creation of the central hole of a tube in an anatomical structure by sealing the edges of an epithelial fold.") @@ -98884,1657 +27001,6 @@ AnnotationAssertion( "tube closure") SubClassOf( ) -# Class: (mesenchymal cell differentiation involved in mammary gland development) - -AnnotationAssertion(Annotation( "GOC:dph") "The process in which a relatively unspecialized cell acquires specialized features of a mammary gland mesenchymal cell. Mammary gland mesenchymal cells form a loosely connected network of cells that surround the mammary ducts.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-05-15T12:17:06Z") -AnnotationAssertion(Annotation( "GOC:dph") "mammary gland mesenchymal cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060610") -AnnotationAssertion(rdfs:label "mesenchymal cell differentiation involved in mammary gland development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (mammary gland fat development) - -AnnotationAssertion(Annotation( "GOC:dph") "The progression of the mammary gland fat over time, from its formation to the mature structure. The mammary fat is an adipose structure in the gland that is invaded by the mammary ducts.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-05-15T12:27:57Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060611") -AnnotationAssertion(rdfs:label "mammary gland fat development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (adipose tissue development) - -AnnotationAssertion(Annotation( "GOC:dph") "The process whose specific outcome is the progression of adipose tissue over time, from its formation to the mature structure. Adipose tissue is specialized tissue that is used to store fat.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-05-15T12:36:28Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:sl") "adipogenesis") -AnnotationAssertion( "GO:0060612") -AnnotationAssertion(rdfs:label "adipose tissue development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (fat pad development) - -AnnotationAssertion(Annotation( "GOC:dph") "The progression of a fat pad from its initial formation to its mature structure. A fat pad is an accumulation of adipose tissue.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-05-15T12:42:08Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060613") -AnnotationAssertion(rdfs:label "fat pad development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (mammary gland bud formation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:12558599") "The morphogenetic process in which a bud forms from the mammary placode. A mammary bud is bulb of epithelial cells that is distinct from the surrounding epidermis.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-05-18T08:43:14Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060615") -AnnotationAssertion(rdfs:label "mammary gland bud formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (mammary gland cord formation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:12558599") "The process in which the mammary gland cord forms by elongation of the mammary bud. The cord is formed once the elongating bud breaks through the mesenchyme and reaches the fat pad.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-05-18T08:57:58Z") -AnnotationAssertion(Annotation( "GOC:dph") "mammary gland sprout formation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060616") -AnnotationAssertion(rdfs:label "mammary gland cord formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (nipple development) - -AnnotationAssertion(Annotation( "GOC:dph") "The progression of the nipple over time, from its formation to the mature structure. The nipple is a part of the mammary gland that protrudes from the surface ectoderm.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-05-18T09:29:38Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060618") -AnnotationAssertion(rdfs:label "nipple development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cell migration involved in mammary placode formation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:12558599") "The orderly movement of epithelial cells within the mammary line that contributes to the formation of the mammary placode.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-05-18T09:41:49Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060619") -AnnotationAssertion(rdfs:label "cell migration involved in mammary placode formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of chromosome condensation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the rate, frequency, or extent of chromosome condensation, the progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis, in eukaryotic cells.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-05-18T02:12:13Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060623") -AnnotationAssertion(rdfs:label "regulation of chromosome condensation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of vesicle-mediated transport) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the rate, frequency, or extent of vesicle-mediated transport, the directed movement of substances, either within a vesicle or in the vesicle membrane, into, out of or within a cell.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-05-18T02:29:43Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060627") -AnnotationAssertion(rdfs:label "regulation of vesicle-mediated transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of microtubule-based movement) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the rate, frequency, or extent of microtubule-based movement, the movement of organelles, other microtubules and other particles along microtubules, mediated by motor proteins.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-05-18T03:07:02Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060632") -AnnotationAssertion(rdfs:label "regulation of microtubule-based movement") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (white fat cell differentiation involved in mammary gland fat development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:12558599") "The process in which a preadipocyte acquires specialized features of a white adipocyte of the mammary gland. White adipocytes have cytoplasmic lipids arranged in a unique vacuole.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-05-27T05:50:56Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060642") -AnnotationAssertion(rdfs:label "white fat cell differentiation involved in mammary gland fat development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (epithelial cell differentiation involved in mammary gland bud morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") "The process in which a cell of the mammary placode becomes a cell of the mammary gland bud.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-05-29T07:58:13Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060643") -AnnotationAssertion(rdfs:label "epithelial cell differentiation involved in mammary gland bud morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (mammary gland epithelial cell differentiation) - -AnnotationAssertion(Annotation( "GOC:dph") "The process in which a relatively unspecialized epithelial cell becomes a more specialized epithelial cell of the mammary gland.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-05-29T08:03:07Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060644") -AnnotationAssertion(rdfs:label "mammary gland epithelial cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (mesenchymal cell condensation involved in mammary fat development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:12558599") "The cell adhesion process in which mammary mesenchyme cells adhere to one another in the initial stages of the formation of mammary fat development.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-05-29T08:33:29Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060647") -AnnotationAssertion(rdfs:label "mesenchymal cell condensation involved in mammary fat development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (mammary gland bud morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:12558599") "The process in which anatomical structures of the mammary gland buds are generated and organized. Mammary gland buds form by an outpocketing of the mammary placodes and grow to invade the mammary fat, when they form the mammary cord.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-05-29T08:42:22Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060648") -AnnotationAssertion(rdfs:label "mammary gland bud morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (mammary gland cord morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:12558599") "The process in which anatomical structures of the mammary gland cord are generated and organized. Mammary gland cords form when the mammary gland bud invades the mammary fat.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-05-29T09:06:56Z") -AnnotationAssertion(Annotation( "GOC:dph") "mammary gland sprout morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060652") -AnnotationAssertion(rdfs:label "mammary gland cord morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (epithelial cell differentiation involved in mammary gland cord morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:12558599") "The process in which a relatively unspecialized epithelial cell becomes a more specialized epithelial cell of the mammary gland cord. Epithelial cells of the mammary cord give it its funnel-like shape and some are cornified.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-05-29T09:17:16Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") "epithelial cell differentiation involved in mammary gland sprout morphogenesis") -AnnotationAssertion( "GO:0060653") -AnnotationAssertion(rdfs:label "epithelial cell differentiation involved in mammary gland cord morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (branching involved in mammary gland cord morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:12558599") "The process in which the branching structure of the mammary gland cord is generated and organized. The mammary gland cord is a solid epithelial structure that will hollow out, forming the mammary duct.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-05-29T09:29:32Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060655") -AnnotationAssertion(rdfs:label "branching involved in mammary gland cord morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (nipple morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") "The process in which the nipple is generated and organized.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-05-29T10:45:44Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060658") -AnnotationAssertion(rdfs:label "nipple morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (nipple sheath formation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:12558599") "The developmental process pertaining to the initial formation of the nipple sheath from the unspecified epidermis. This process begins with a circular ingrowth of the epidermis around the region of the mammary sprout. It ends before the region begins to elevate.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-05-29T10:48:39Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060659") -AnnotationAssertion(rdfs:label "nipple sheath formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (epidermis morphogenesis involved in nipple formation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:12558599") "The process in which the epidermis of the nipple sheath is uplifted to form an umbrella-like projection.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-05-29T11:04:04Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060660") -AnnotationAssertion(rdfs:label "epidermis morphogenesis involved in nipple formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (submandibular salivary gland formation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:17336109") "The developmental process pertaining to the initial formation of a submandibular salivary gland. This process begins with a thickening of the epithelium next to the tongue and ends when a bud linked to the oral surface is formed.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-06-01T08:07:16Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060661") -AnnotationAssertion(rdfs:label "submandibular salivary gland formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (epithelial cell proliferation involved in salivary gland morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:17336109") "The multiplication or reproduction of epithelial cells of the submandibular salivary gland, resulting in the expansion of a cell population and the shaping of the gland.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-06-01T08:36:13Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060664") -AnnotationAssertion(rdfs:label "epithelial cell proliferation involved in salivary gland morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (embryonic placenta morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") "The process in which the embryonic placenta is generated and organized.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-06-02T09:33:37Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060669") -AnnotationAssertion(rdfs:label "embryonic placenta morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (branching involved in labyrinthine layer morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:16916377") "The process in which the branches of the fetal placental villi are generated and organized. The villous part of the placenta is called the labyrinth layer.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-06-02T10:40:40Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060670") -AnnotationAssertion(rdfs:label "branching involved in labyrinthine layer morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (epithelial cell differentiation involved in embryonic placenta development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:16916377") "The process in which a trophoblast cell acquires specialized features of an epithelial cell of the placental labyrinthine layer.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-06-02T11:40:52Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060671") -AnnotationAssertion(rdfs:label "epithelial cell differentiation involved in embryonic placenta development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cell-cell signaling involved in placenta development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:16916377") "Any process that mediates the transfer of information from one cell to another.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-06-02T12:58:03Z") -AnnotationAssertion(Annotation( "GOC:mah") "cell-cell signalling involved in placenta development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060673") -AnnotationAssertion(rdfs:label "cell-cell signaling involved in placenta development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (placenta blood vessel development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:16916377") "The process whose specific outcome is the progression of a blood vessel of the placenta over time, from its formation to the mature structure.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-06-02T01:09:43Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060674") -AnnotationAssertion(rdfs:label "placenta blood vessel development") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (ureteric bud morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_kidney_jan10") "The process in which the ureteric bud is generated and organized.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-06-02T01:31:41Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060675") -AnnotationAssertion(rdfs:label "ureteric bud morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (ureteric bud formation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:16916378") "The developmental process pertaining to the initial formation of the ureteric bud from the Wolffian duct. This process begins when the bud protrudes from the duct and ends when it is a recognizable bud.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-06-02T01:47:23Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060676") -AnnotationAssertion(rdfs:label "ureteric bud formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (ureteric bud elongation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:16916378") "The developmental growth in which the ureteric bud grows along its axis beginning with the growth of the primary ureteric bud and ending when the branches of the bud have elongated.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-06-02T02:13:29Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060677") -AnnotationAssertion(rdfs:label "ureteric bud elongation") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (lateral sprouting involved in ureteric bud morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:16916378") "The process in which a branch forms along the side of a ureteric bud.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-06-02T02:44:27Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060680") -AnnotationAssertion(rdfs:label "lateral sprouting involved in ureteric bud morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (primary ureteric bud growth) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:16916378") "The process in which the primary ureteric bud grows along its axis dorsally toward the metanephric blastema.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-06-02T02:56:01Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060682") -AnnotationAssertion(rdfs:label "primary ureteric bud growth") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (regulation of prostatic bud formation) - -AnnotationAssertion(Annotation( "GOC:dph") "Any process that modulates the rate, frequency, or extent of prostatic bud formation, the morphogenetic process in which a region of the fetal urogenital sinus epithelium is specified to become the prostate, resulting in prostate bud outgrowth.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-06-05T12:29:26Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060685") -AnnotationAssertion(rdfs:label "regulation of prostatic bud formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (negative regulation of prostatic bud formation) - -AnnotationAssertion(Annotation( "GOC:dph") "Any process that decreases the rate, frequency, or extent of prostatic bud formation, the morphogenetic process in which a region of the fetal urogenital sinus epithelium is specified to become the prostate, resulting in prostate bud outgrowth.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-06-05T12:35:25Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060686") -AnnotationAssertion(rdfs:label "negative regulation of prostatic bud formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of branching involved in prostate gland morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") "Any process that modulates the rate, frequency, or extent of prostate gland branching, the process in which the branching structure of the prostate gland is generated and organized. A branch is a division or offshoot from a main stem.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-06-05T12:37:14Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060687") -AnnotationAssertion(rdfs:label "regulation of branching involved in prostate gland morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of morphogenesis of a branching structure) - -AnnotationAssertion(Annotation( "GOC:dph") "Any process that modulates the rate, frequency, or extent of branching morphogenesis, the process in which the anatomical structures of branches are generated and organized.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-06-05T12:41:44Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060688") -AnnotationAssertion(rdfs:label "regulation of morphogenesis of a branching structure") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (cell differentiation involved in salivary gland development) - -AnnotationAssertion(Annotation( "GOC:dph") "The process in which a relatively unspecialized cell acquires specialized structural and/or functional features that characterize the cells of the salivary gland.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-06-08T01:01:35Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060689") -AnnotationAssertion(rdfs:label "cell differentiation involved in salivary gland development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (epithelial cell differentiation involved in salivary gland development) - -AnnotationAssertion(Annotation( "GOC:dph") "The process in which a relatively unspecialized cell acquire specialized structural and/or functional features of an epithelial cell of the salivary gland.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-06-08T01:04:19Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060690") -AnnotationAssertion(rdfs:label "epithelial cell differentiation involved in salivary gland development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (epithelial cell maturation involved in salivary gland development) - -AnnotationAssertion(Annotation( "GOC:dph") "The developmental process, independent of morphogenetic (shape) change, that is required for an epithelial cell of the salivary gland to attain its fully functional state.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-06-08T01:06:00Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060691") -AnnotationAssertion(rdfs:label "epithelial cell maturation involved in salivary gland development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (mesenchymal cell differentiation involved in salivary gland development) - -AnnotationAssertion(Annotation( "GOC:dph") "The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal cell of the salivary gland. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-06-08T01:08:44Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060692") -AnnotationAssertion(rdfs:label "mesenchymal cell differentiation involved in salivary gland development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of branching involved in salivary gland morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") "Any process that modulates the rate, frequency, or extent of branching morphogenesis in the salivary gland epithelium.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-06-08T01:14:44Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060693") -AnnotationAssertion(rdfs:label "regulation of branching involved in salivary gland morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of phospholipid catabolic process) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the rate, frequency, or extent of phospholipid catabolism, the chemical reactions and pathways resulting in the breakdown of phospholipids, any lipid containing phosphoric acid as a mono- or diester.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-06-08T02:25:45Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060696") -AnnotationAssertion(rdfs:label "regulation of phospholipid catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of phospholipid catabolic process) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that increases the rate, frequency, or extent of phospholipid catabolism, the chemical reactions and pathways resulting in the breakdown of phospholipids, any lipid containing phosphoric acid as a mono- or diester.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-06-08T02:28:38Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060697") -AnnotationAssertion(rdfs:label "positive regulation of phospholipid catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (acinar cell differentiation involved in salivary gland development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "The process in which a relatively unspecialized cell acquires specialized structural and/or functional features that characterize an acinar cell of the salivary gland. Acinar cells are protein-secreting cells in the gland.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-06-09T09:32:46Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060704") -AnnotationAssertion(rdfs:label "acinar cell differentiation involved in salivary gland development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (neuron differentiation involved in salivary gland development) - -AnnotationAssertion(Annotation( "GOC:dph") "The process in which a relatively unspecialized cell acquires specialized structural and/or functional features that characterize the neurons of the salivary gland.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-06-09T09:35:52Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060705") -AnnotationAssertion(rdfs:label "neuron differentiation involved in salivary gland development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cell differentiation involved in embryonic placenta development) - -AnnotationAssertion(Annotation( "GOC:dph") "The process in which a relatively unspecialized cell acquires specialized features of the embryonic placenta.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-06-09T10:26:42Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060706") -AnnotationAssertion(rdfs:label "cell differentiation involved in embryonic placenta development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (spongiotrophoblast differentiation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:16269175") "The process in which a relatively unspecialized cell of the ectoplacental cone acquires specialized features of a spongiotrophoblast of the placenta. A spongiotrophoblast cell is a basophilic cell.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-06-09T10:38:10Z") -AnnotationAssertion(Annotation( "GOC:cjm") "spongiotrophoblast cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060708") -AnnotationAssertion(rdfs:label "spongiotrophoblast differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (labyrinthine layer development) - -AnnotationAssertion(Annotation( "GOC:dph") "The process in which the labyrinthine layer of the placenta progresses, from its formation to its mature state.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-06-09T03:27:43Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060711") -AnnotationAssertion(rdfs:label "labyrinthine layer development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (spongiotrophoblast layer development) - -AnnotationAssertion(Annotation( "GOC:dph") "The process in which the spongiotrophoblast layer of the placenta progresses from its formation to its mature state.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-06-09T03:33:40Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060712") -AnnotationAssertion(rdfs:label "spongiotrophoblast layer development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (labyrinthine layer morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") "The process in which the labyrinthine layer of the placenta is generated and organized.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-06-10T08:10:19Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060713") -AnnotationAssertion(rdfs:label "labyrinthine layer morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (labyrinthine layer formation) - -AnnotationAssertion(Annotation( "GOC:dph") "The developmental process pertaining to the initial formation of the labyrinthine layer of the placenta.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-06-10T08:13:14Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060714") -AnnotationAssertion(rdfs:label "labyrinthine layer formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (labyrinthine layer blood vessel development) - -AnnotationAssertion(Annotation( "GOC:dph") "The process whose specific outcome is the progression of a blood vessel of the labyrinthine layer of the placenta over time, from its formation to the mature structure. The embryonic vessels grow through the layer to come in close contact with the maternal blood supply.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-06-11T09:04:38Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060716") -AnnotationAssertion(rdfs:label "labyrinthine layer blood vessel development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (chorion development) - -AnnotationAssertion(Annotation( "GOC:dph") "The biological process whose specific outcome is the progression of a chorion from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The chorion is an extraembryonic membrane.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-06-11T02:37:50Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060717") -AnnotationAssertion(rdfs:label "chorion development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (chorionic trophoblast cell differentiation) - -AnnotationAssertion(Annotation( "CL:0011101") Annotation( "GOC:dph") Annotation( "PMID:16983341") "The process in which relatively unspecialized cells of the ectoplacental cone acquire specialized structural and/or functional features that characterize chorionic trophoblasts. These cells will migrate towards the spongiotrophoblast layer and give rise to syncytiotrophoblasts of the labyrinthine layer.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-06-11T02:48:27Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060718") -AnnotationAssertion(rdfs:label "chorionic trophoblast cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (chorionic trophoblast cell development) - -AnnotationAssertion(Annotation( "CL:0011101") Annotation( "GOC:16983341") Annotation( "GOC:dph") "The process whose specific outcome is the progression of the chorionic trophoblast over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-06-11T02:58:45Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060719") -AnnotationAssertion(rdfs:label "chorionic trophoblast cell development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cell proliferation involved in embryonic placenta development) - -AnnotationAssertion(Annotation( "GOC:dph") "The multiplication or reproduction of cells, resulting in the expansion of the population in the embryonic placenta.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-06-12T12:46:04Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060722") -AnnotationAssertion(rdfs:label "cell proliferation involved in embryonic placenta development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of cell proliferation involved in embryonic placenta development) - -AnnotationAssertion(Annotation( "GOC:dph") "Any process that modulates the rate, frequency, or extent of cell proliferation involved in embryonic placenta development.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-06-12T12:50:23Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060723") -AnnotationAssertion(rdfs:label "regulation of cell proliferation involved in embryonic placenta development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (prostate gland growth) - -AnnotationAssertion(Annotation( "GOC:dph") "The increase in size or mass of the prostate gland where the increase in size or mass has the specific outcome of the progression of the gland, from its formation to its mature state.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-06-15T09:21:52Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060736") -AnnotationAssertion(rdfs:label "prostate gland growth") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (prostate gland morphogenetic growth) - -AnnotationAssertion(Annotation( "GOC:dph") "The differential increase in size or mass of the prostate gland that contributes to the gland attaining its form.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-06-15T09:24:40Z") -AnnotationAssertion(Annotation( "GOC:dph") "prostate gland growth involved in morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060737") -AnnotationAssertion(rdfs:label "prostate gland morphogenetic growth") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (prostate gland epithelium morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") "The process in which the anatomical structures of epithelia of the prostate gland are generated and organized. An epithelium consists of closely packed cells arranged in one or more layers, that covers the outer surfaces of the body or lines any internal cavity or tube.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-06-16T09:23:22Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060740") -AnnotationAssertion(rdfs:label "prostate gland epithelium morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (prostate gland stromal morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") "The process in which the prostate gland stroma is generated and organized. The prostate gland stroma is made up of the mesenchymal or fibroblast cells of the prostate gland.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-06-16T09:27:01Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060741") -AnnotationAssertion(rdfs:label "prostate gland stromal morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (epithelial cell differentiation involved in prostate gland development) - -AnnotationAssertion(Annotation( "GOC:dph") "The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell of the prostate gland.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-06-16T09:32:34Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060742") -AnnotationAssertion(rdfs:label "epithelial cell differentiation involved in prostate gland development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (epithelial cell maturation involved in prostate gland development) - -AnnotationAssertion(Annotation( "GOC:dph") "The developmental process, independent of morphogenetic (shape) change, that is required for an epithelial cell of the prostate gland to attain its fully functional state. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-06-16T09:34:42Z") -AnnotationAssertion(Annotation( "GOC:dph") "prostate gland epithelial cell development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060743") -AnnotationAssertion(rdfs:label "epithelial cell maturation involved in prostate gland development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (mammary gland alveolus development) - -AnnotationAssertion(Annotation( "GOC:dph") "The progression of the mammary gland alveolus over time, from its formation to its mature state. The mammary gland alveolus is a sac-like structure that is found in the mature gland.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-06-22T10:52:12Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060749") -AnnotationAssertion(rdfs:label "mammary gland alveolus development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (regulation of response to cytokine stimulus) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the rate, frequency, or extent of a response to cytokine stimulus.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-06-22T02:56:12Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060759") -AnnotationAssertion(rdfs:label "regulation of response to cytokine stimulus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of response to cytokine stimulus) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that increases the rate, frequency, or extent of a response to cytokine stimulus.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-06-22T02:58:04Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060760") -AnnotationAssertion(rdfs:label "positive regulation of response to cytokine stimulus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of response to cytokine stimulus) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that decreases the rate, frequency, or extent of a response to cytokine stimulus.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-06-22T02:59:57Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060761") -AnnotationAssertion(rdfs:label "negative regulation of response to cytokine stimulus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of branching involved in mammary gland duct morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") "Any process that modulates the rate, frequency, or extent of branching involved in mammary gland duct morphogenesis.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-06-22T05:20:33Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060762") -AnnotationAssertion(rdfs:label "regulation of branching involved in mammary gland duct morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (mammary duct terminal end bud growth) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:10804170") "The morphogenetic growth of the large, club-shaped terminal end of a mammary gland duct during prepubertal growth and during puberty.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-07-06T07:33:50Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060763") -AnnotationAssertion(rdfs:label "mammary duct terminal end bud growth") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cell-cell signaling involved in mammary gland development) - -AnnotationAssertion(Annotation( "GOC:dph") "Any process that mediates the transfer of information from one cell to another and contributes to the progression of the mammary gland, from its initial state to the mature structure.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-07-06T09:24:53Z") -AnnotationAssertion(Annotation( "GOC:mah") "cell-cell signalling involved in mammary gland development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060764") -AnnotationAssertion(rdfs:label "cell-cell signaling involved in mammary gland development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (epithelial cell proliferation involved in prostate gland development) - -AnnotationAssertion(Annotation( "GOC:dph") "The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population that contributes to the progression of the prostate gland over time.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-07-08T07:32:34Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060767") -AnnotationAssertion(rdfs:label "epithelial cell proliferation involved in prostate gland development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of epithelial cell proliferation involved in prostate gland development) - -AnnotationAssertion(Annotation( "GOC:dph") "Any process that modulates the rate, frequency or extent of epithelial cell proliferation that contributes to the progression of the prostate gland over time.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-07-08T07:34:56Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060768") -AnnotationAssertion(rdfs:label "regulation of epithelial cell proliferation involved in prostate gland development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of epithelial cell proliferation involved in prostate gland development) - -AnnotationAssertion(Annotation( "GOC:dph") "Any process that increases the rate, frequency or extent of epithelial cell proliferation that contributes to the progression of the prostate gland over time.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-07-08T07:38:02Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060769") -AnnotationAssertion(rdfs:label "positive regulation of epithelial cell proliferation involved in prostate gland development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (negative regulation of epithelial cell proliferation involved in prostate gland development) - -AnnotationAssertion(Annotation( "GOC:dph") "Any process that decreases the rate, frequency or extent of epithelial cell proliferation that contributes to the progression of the prostate gland over time.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-07-08T07:40:27Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060770") -AnnotationAssertion(rdfs:label "negative regulation of epithelial cell proliferation involved in prostate gland development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (mesenchymal cell proliferation involved in prostate gland development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:12221011") "The multiplication or reproduction of mesenchymal cells, resulting in the expansion of a cell population that contributes to the progression of the prostate gland over time.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-07-28T11:50:56Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060781") -AnnotationAssertion(rdfs:label "mesenchymal cell proliferation involved in prostate gland development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of mesenchymal cell proliferation involved in prostate gland development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:12221011") "Any process that modulates the frequency, rate or extent of mesenchymal cell proliferation that contributes to the progression of the prostate gland over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-07-28T11:54:20Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060782") -AnnotationAssertion(rdfs:label "regulation of mesenchymal cell proliferation involved in prostate gland development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of cell proliferation involved in tissue homeostasis) - -AnnotationAssertion(Annotation( "GOC:dph") "Any process that modulates the frequency, rate or extent of cell proliferation resulting in the maintenance of a steady-state number of cells within a tissue.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-07-31T01:46:28Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060784") -AnnotationAssertion(rdfs:label "regulation of cell proliferation involved in tissue homeostasis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (regulation of apoptosis involved in tissue homeostasis) - -AnnotationAssertion(Annotation( "GOC:dph") "Any process that modulates the occurrence or rate of cell death by apoptosis that results in the maintenance of the steady-state number of cells within a tissue.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-07-31T01:49:54Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060785") -AnnotationAssertion(rdfs:label "regulation of apoptosis involved in tissue homeostasis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (regulation of cell differentiation involved in tissue homeostasis) - -AnnotationAssertion(Annotation( "GOC:dph") "Any process that modulates the frequency, rate or extent of cell differentiation that contributes to the maintenance of a steady state of a cell type within a tissue.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-07-31T01:55:19Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060786") -AnnotationAssertion(rdfs:label "regulation of cell differentiation involved in tissue homeostasis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (ectodermal placode formation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:sdb_2009") Annotation( "GOC:tb") "The developmental process in which an ectodermal placode forms. An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-08-04T12:15:57Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060788") -AnnotationAssertion(rdfs:label "ectodermal placode formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (hair follicle placode formation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:sdb_2009") Annotation( "GOC:tb") "The developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-08-04T12:18:26Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060789") -AnnotationAssertion(rdfs:label "hair follicle placode formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (tooth placode formation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:sdb_2009") Annotation( "GOC:tb") "The developmental process in which the tooth placode forms. A tooth placode is a thickening of the ectoderm that will give rise to the tooth bud.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-08-04T12:21:47Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060790") -AnnotationAssertion(rdfs:label "tooth placode formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (sebaceous gland placode formation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:sdb_2009") Annotation( "GOC:tb") "The developmental process in which a sebaceous gland placode forms. A sebaceous gland placode is a thickening of the ectoderm that will give rise to the sebaceous gland bud.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-08-04T12:23:09Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060791") -AnnotationAssertion(rdfs:label "sebaceous gland placode formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (sweat gland development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:sdb_2009") Annotation( "GOC:tb") "The progression of the sweat gland over time, from its formation to the mature structure. Sweat glands secrete an aqueous solution that is used in thermoregulation.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-08-04T12:35:12Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060792") -AnnotationAssertion(rdfs:label "sweat gland development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (sweat gland placode formation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:sdb_2009") Annotation( "GOC:tb") "The developmental process in which the sweat gland placode forms. An sweat gland placode is a thickening of the ectoderm that will give rise to the sweat gland bud.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-08-04T12:38:10Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060793") -AnnotationAssertion(rdfs:label "sweat gland placode formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cell fate commitment involved in formation of primary germ layer) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:sdb_2009") Annotation( "GOC:tb") "The commitment of cells to specific cell fates of the endoderm, ectoderm, or mesoderm as a part of gastrulation.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-08-04T03:11:22Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060795") -AnnotationAssertion(rdfs:label "cell fate commitment involved in formation of primary germ layer") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of cell differentiation involved in embryonic placenta development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:sdb_2009") Annotation( "GOC:tb") "Any process that modulates the rate, frequency or extent of cell differentiation that contributes to the progression of the placenta over time, from its initial condition to its mature state.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-08-06T01:20:25Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060800") -AnnotationAssertion(rdfs:label "regulation of cell differentiation involved in embryonic placenta development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of cell differentiation involved in embryonic placenta development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:sdb_2009") Annotation( "GOC:tb") "Any process that decreases the rate, frequency or extent of cell differentiation that contributes to the progression of the placenta over time, from its initial condition to its mature state.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-08-06T02:02:18Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060806") -AnnotationAssertion(rdfs:label "negative regulation of cell differentiation involved in embryonic placenta development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of translation involved in anterior/posterior axis specification) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:sdb_2009") Annotation( "GOC:tb") "Any process that modulates the frequency, rate or extent of translation of mRNAs that contribute to the specification of the anterior/posterior axis.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-08-07T10:02:31Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060815") -AnnotationAssertion(rdfs:label "regulation of translation involved in anterior/posterior axis specification") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (lymphatic endothelial cell differentiation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:sdb_2009") Annotation( "GOC:tb") "The process in which a venous blood vessel endothelial cell acquires specialized features of a lymphatic vessel endothelial cell, a thin flattened cell that lines the inside surfaces of lymph vessels.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-08-11T03:45:20Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060836") -AnnotationAssertion(rdfs:label "lymphatic endothelial cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (blood vessel endothelial cell differentiation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:sdb_2009") Annotation( "GOC:tb") "The process in which a relatively unspecialized cell acquires specialized features of a blood vessel endothelial cell, a thin flattened cell that lines the inside surfaces of blood vessels.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-08-11T03:47:36Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060837") -AnnotationAssertion(rdfs:label "blood vessel endothelial cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (artery development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:sdb_2009") Annotation( "GOC:tb") "The progression of the artery over time, from its initial formation to the mature structure. An artery is a blood vessel that carries blood away from the heart to a capillary bed.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-08-12T10:10:51Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060840") -AnnotationAssertion(rdfs:label "artery development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (venous blood vessel development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:sdb_2009") Annotation( "GOC:tb") "The progression of the venous blood vessel over time from its initial formation to the mature structure. Venous blood vessels carry blood back to the heart after the capillary bed.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-08-12T10:14:07Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060841") -AnnotationAssertion(rdfs:label "venous blood vessel development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (arterial endothelial cell differentiation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:sdb_2009") Annotation( "GOC:tb") "The process in which a relatively unspecialized endothelial cell acquires specialized features of an arterial endothelial cell, a thin flattened cell that lines the inside surfaces of arteries.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-08-12T10:41:34Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060842") -AnnotationAssertion(rdfs:label "arterial endothelial cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (venous endothelial cell differentiation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:sdb_2009") Annotation( "GOC:tb") "The process in which a relatively unspecialized endothelial cell acquires specialized features of a venous endothelial cell, a thin flattened cell that lines the inside surfaces of veins.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-08-12T10:43:40Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060843") -AnnotationAssertion(rdfs:label "venous endothelial cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (branching involved in lymph vessel morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:sdb_2009") Annotation( "GOC:tb") "The process of the coordinated growth and sprouting of lymph vessels giving rise to the organized lymphatic system.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-08-12T12:00:48Z") -AnnotationAssertion(Annotation( "GOC:dph") "patterning of lymph vessels") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060854") -AnnotationAssertion(rdfs:label "branching involved in lymph vessel morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (semicircular canal development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:sdb_2009") Annotation( "GOC:tb") "The progression of the semicircular canal from its initial formation to the mature structure.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-08-13T09:36:37Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060872") -AnnotationAssertion(rdfs:label "semicircular canal development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (anterior semicircular canal development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:sdb_2009") Annotation( "GOC:tb") "The progession of the anterior semicircular canal from its initial formation to the mature structure.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-08-13T09:39:49Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060873") -AnnotationAssertion(rdfs:label "anterior semicircular canal development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (posterior semicircular canal development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:sdb_2009") Annotation( "GOC:tb") "The progession of the posterior semicircular canal from its initial formation to the mature structure.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-08-13T09:42:39Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060874") -AnnotationAssertion(rdfs:label "posterior semicircular canal development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (lateral semicircular canal development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:sdb_2009") Annotation( "GOC:tb") "The progession of the lateral semicircular canal from its initial formation to the mature structure.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-08-13T09:43:25Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060875") -AnnotationAssertion(rdfs:label "lateral semicircular canal development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (semicircular canal formation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:sdb_2009") Annotation( "GOC:tb") "The developmental process pertaining to the initial formation of the semicircular canal from the otic vesicle. This process begins with the regionalization of the vesicle that specifies the area where the vesicles will form and continues through the process of fusion which forms the initial tubes.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-08-13T09:45:07Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060876") -AnnotationAssertion(rdfs:label "semicircular canal formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (regionalization involved in semicircular canal formation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:sdb_2009") Annotation( "GOC:tb") "The pattern specification process that results in the subdivision of the otic epithelium in space to define an area or volume in which cells will differentiate to give rise to the semicircular canals.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-08-13T09:56:45Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060877") -AnnotationAssertion(rdfs:label "regionalization involved in semicircular canal formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (pouch outgrowth involved in semicircular canal formation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:sdb_2009") Annotation( "GOC:tb") "The morphogenetic process in which an epithelial sheet bends along a linear axis and gives rise to a pouch that will form a semicircular canal.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-08-13T10:01:01Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060878") -AnnotationAssertion(rdfs:label "pouch outgrowth involved in semicircular canal formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (semicircular canal fusion) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:sdb_2009") Annotation( "GOC:tb") "Creation of the central hole of the semicircular canal by sealing the edges of the pouch that forms during the process of semicircular canal formation.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-08-13T10:05:51Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060879") -AnnotationAssertion(rdfs:label "semicircular canal fusion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cell morphogenesis involved in semicircular canal fusion) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:sdb_2009") Annotation( "GOC:tb") "The change in form (cell shape and size) that occurs when a semicircular canal epithelial cell acquires the structural features that allow it to contribute to the process of semicircular canal fusion.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-08-13T10:13:25Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060880") -AnnotationAssertion(rdfs:label "cell morphogenesis involved in semicircular canal fusion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (basement membrane disassembly involved in semicircular canal fusion) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:sdb_2009") Annotation( "GOC:tb") "A process that results in the breakdown of the basement membrane that contributes to the process of semicircular canal fusion.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-08-13T11:29:52Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "basal lamina disassembly involved in semicircular canal fusion") -AnnotationAssertion( "GO:0060882") -AnnotationAssertion(rdfs:label "basement membrane disassembly involved in semicircular canal fusion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (limb epidermis development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:sdb_2009") Annotation( "GOC:tb") "The process whose specific outcome is the progression of the epidermis of the limb over time, from its formation to the mature structure. The limb epidermis is the outer epithelial layer of the limb, it is a complex stratified squamous epithelium.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-08-13T12:39:39Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060887") -AnnotationAssertion(rdfs:label "limb epidermis development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (neural plate pattern specification) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:sdb_2009") Annotation( "GOC:tb") "The developmental process that results in the creation of defined areas or spaces within the neural plate to which cells respond and eventually are instructed to differentiate.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-08-13T02:06:27Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060896") -AnnotationAssertion(rdfs:label "neural plate pattern specification") -SubClassOf( ) - -# Class: (neural plate regionalization) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:sdb_2009") Annotation( "GOC:tb") "The pattern specification process that results in the subdivision of an axis or axes of the neural plate in space to define an area or volume in which specific patterns of cell differentiation will take place or in which cells interpret a specific environment.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-08-13T02:09:04Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060897") -AnnotationAssertion(rdfs:label "neural plate regionalization") -SubClassOf( ) -SubClassOf( ) - -# Class: (embryonic camera-type eye formation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:sdb_2009") Annotation( "GOC:tb") "The developmental process pertaining to the initial formation of a camera-type eye from unspecified neurectoderm. This process begins with the differentiation of cells that form the optic field and ends when the optic cup has attained its shape.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-08-13T02:26:54Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060900") -AnnotationAssertion(rdfs:label "embryonic camera-type eye formation") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (positive regulation of macrophage cytokine production) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that increases the rate, frequency or extent of macrophage cytokine production. Macrophage cytokine production is the appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-09-04T02:32:18Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060907") -AnnotationAssertion(rdfs:label "positive regulation of macrophage cytokine production") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (heart formation) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The developmental process pertaining to the initial formation of the heart from unspecified parts. This process begins with the specific processes that contribute to the appearance of the heart field and the arrival of cardiac neural crest to the heart region. The process ends when the structural rudiment is recognizable.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-09-17T09:02:13Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:mtg_heart") "cardiogenesis") -AnnotationAssertion( "GO:0060914") -AnnotationAssertion(rdfs:label "heart formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (mesenchymal cell differentiation involved in lung development) - -AnnotationAssertion(Annotation( "GOC:dph") "The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal cell of the lung. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-09-18T11:45:33Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060915") -AnnotationAssertion(rdfs:label "mesenchymal cell differentiation involved in lung development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (mesenchymal cell proliferation involved in lung development) - -AnnotationAssertion(Annotation( "GOC:dph") "The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population that contributes to the progression of the lung over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-09-18T11:50:17Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060916") -AnnotationAssertion(rdfs:label "mesenchymal cell proliferation involved in lung development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cardiac pacemaker cell differentiation) - -AnnotationAssertion(Annotation( "GOC:mtg_cardiac_conduct_nov11") Annotation( "GOC:mtg_heart") "The process in which a relatively unspecialized cell acquires specialized features of a pacemaker cell. Pacemaker cells are specialized cardiomyocytes that are responsible for regulating the timing of heart contractions.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-09-29T11:01:31Z") -AnnotationAssertion( "pacemaker cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060920") -AnnotationAssertion(rdfs:label "cardiac pacemaker cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (sinoatrial node cell differentiation) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which a relatively unspecialized cell acquires specialized features of a sinoatrial (SA) node cell. SA node cells are pacemaker cells that are found in the sinoatrial node.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-09-29T11:03:30Z") -AnnotationAssertion(Annotation( "GOC:mtg_heart") "SA node cell differentiation") -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mtg_cardiac_conduct_nov11") "SAN cell differentiation") -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mtg_cardiac_conduct_nov11") "sinus node cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060921") -AnnotationAssertion(rdfs:label "sinoatrial node cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (atrioventricular node cell differentiation) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which a relatively unspecialized cell acquires specialized features of an atrioventricular (AV) node cell. AV node cells are pacemaker cells that are found in the atrioventricular node.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-09-29T11:07:06Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:mtg_heart") "AV node cell differentiation") -AnnotationAssertion( "GO:0060922") -AnnotationAssertion(rdfs:label "atrioventricular node cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cardiac pacemaker cell development) - -AnnotationAssertion(Annotation( "GOC:mtg_cardiac_conduct_nov11") Annotation( "GOC:mtg_heart") "The process whose specific outcome is the progression of a pacemaker cell over time, from its formation to the mature state. Pacemaker cells are specialized cardiomyocytes that are responsible for regulating the timing of heart contractions.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-09-29T11:51:55Z") -AnnotationAssertion( "pacemaker cell development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060926") -AnnotationAssertion(rdfs:label "cardiac pacemaker cell development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (atrioventricular node cell development) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process whose specific outcome is the progression of an atrioventricular (AV) node cell over time, from its formation to the mature state.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-09-29T11:59:26Z") -AnnotationAssertion(Annotation( "GOC:mtg_heart") "AV node cell development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060928") -AnnotationAssertion(rdfs:label "atrioventricular node cell development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (sinoatrial node cell development) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process whose specific outcome is the progression of a sinoatrial (SA) node cell over time, from its formation to the mature state. SA node cells are pacemaker cells that are found in the sinoatrial node.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-09-29T12:05:47Z") -AnnotationAssertion(Annotation( "GOC:mtg_heart") "SA node cell development") -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mtg_cardiac_conduct_nov11") "SAN cell development") -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mtg_cardiac_conduct_nov11") "sinus node cell development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060931") -AnnotationAssertion(rdfs:label "sinoatrial node cell development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (His-Purkinje system cell differentiation) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell of the His-Purkinje system. These cells form the fibers regulate cardiac muscle contraction in the ventricles.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-09-29T01:10:32Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060932") -AnnotationAssertion(rdfs:label "His-Purkinje system cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (His-Purkinje system cell development) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process whose specific outcome is the progression of a His-Purkinje cell over time, from its formation to the mature state. These cells form the fibers that regulate cardiac muscle contraction in the ventricles.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-09-29T01:15:02Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060933") -AnnotationAssertion(rdfs:label "His-Purkinje system cell development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cardiac fibroblast cell differentiation) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cardiac fibroblast. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-09-29T01:20:04Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060935") -AnnotationAssertion(rdfs:label "cardiac fibroblast cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (cardiac fibroblast cell development) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process whose specific outcome is the progression of a cardiac fibroblast over time, from its formation to the mature state. A cardiac fibroblast is a connective tissue cell of the heart which secretes an extracellular matrix rich in collagen and other macromolecules.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-09-29T01:23:03Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060936") -AnnotationAssertion(rdfs:label "cardiac fibroblast cell development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cardiac neuron differentiation) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which a relatively unspecialized cell acquires specialized features of a neuron of the heart.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-09-29T02:45:33Z") -AnnotationAssertion(Annotation( "GOC:mtg_heart") "heart neuron differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060945") -AnnotationAssertion(rdfs:label "cardiac neuron differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cardiac blood vessel endothelial cell differentiation) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which a relatively unspecialized cell acquires specialized features of a blood vessel endothelial cell of the heart. Blood vessel endothelial cells are thin flattened cells that line the inside surfaces of blood vessels.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-09-29T02:48:55Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060946") -AnnotationAssertion(rdfs:label "cardiac blood vessel endothelial cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (cardiac glial cell differentiation) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which a relatively unspecialized cell acquires the specialized features of a glial cell of the heart.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-09-29T03:06:37Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060950") -AnnotationAssertion(rdfs:label "cardiac glial cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (cardiac glial cell development) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process aimed at the progression of a cardiac glial cell over time, from its formation to the fully functional mature cell.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-09-29T03:09:24Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060952") -AnnotationAssertion(rdfs:label "cardiac glial cell development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (endocardial cell differentiation) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an endocardial cell. An endocardial cell is a specialized endothelial cell that makes up the endocardium portion of the heart. The endocardium is the innermost layer of tissue of the heart, and lines the heart chambers.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-09-29T03:20:39Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060956") -AnnotationAssertion(rdfs:label "endocardial cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (endocardial cell development) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The progression of an endocardial cell over time, from its formation to the mature cell. An endocardial cell is a specialized endothelial cell that makes up the endocardium portion of the heart.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-09-29T03:26:59Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060958") -AnnotationAssertion(rdfs:label "endocardial cell development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cardiac neuron development) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process whose specific outcome is the progression of a cardiac neuron over time, from its formation to the mature state.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-09-30T10:14:56Z") -AnnotationAssertion(Annotation( "GOC:mtg_heart") "heart neuron development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060959") -AnnotationAssertion(rdfs:label "cardiac neuron development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cell migration involved in heart development) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The orderly movement of a cell from one site to another that will contribute to the progression of the heart over time, from its initial formation, to the mature organ.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-06T10:53:49Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060973") -AnnotationAssertion(rdfs:label "cell migration involved in heart development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cell migration involved in heart formation) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The orderly movement of a cell from one site to another that contribute to the formation of the heart. The initial heart structure is made up of mesoderm-derived heart progenitor cells and neural crest-derived cells.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-06T10:56:33Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060974") -AnnotationAssertion(rdfs:label "cell migration involved in heart formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (coronary vasculature development) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process whose specific outcome is the progression of the blood vessels of the heart over time, from its formation to the mature structure.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-06T12:15:23Z") -AnnotationAssertion(Annotation( "GOC:mtg_heart") "cardiac blood vessel development") -AnnotationAssertion(Annotation( "GOC:mtg_heart") "cardiac vasculature development") -AnnotationAssertion(Annotation( "GOC:mtg_heart") "coronary blood vessel development") -AnnotationAssertion(Annotation( "GOC:mtg_heart") "heart blood vessel development") -AnnotationAssertion(Annotation( "GOC:mtg_heart") "heart vasculature development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060976") -AnnotationAssertion(rdfs:label "coronary vasculature development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (coronary vasculature morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which the anatomical structures of blood vessels of the heart are generated and organized. The blood vessel is the vasculature carrying blood.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-06T12:28:23Z") -AnnotationAssertion(Annotation( "GOC:mtg_heart") "cardiac blood vessel morphogenesis") -AnnotationAssertion(Annotation( "GOC:mtg_heart") "cardiac vasculature morphogenesis") -AnnotationAssertion(Annotation( "GOC:mtg_heart") "coronary blood vessel morphogenesis") -AnnotationAssertion(Annotation( "GOC:mtg_heart") "heart blood vessel morphogenesis") -AnnotationAssertion(Annotation( "GOC:mtg_heart") "heart vasculature morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060977") -AnnotationAssertion(rdfs:label "coronary vasculature morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (angiogenesis involved in coronary vascular morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "Blood vessel formation in the heart when new vessels emerge from the proliferation of pre-existing blood vessels.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-06T02:02:12Z") -AnnotationAssertion(Annotation( "GOC:mtg_heart") "angiogenesis involved in cardiac vascular morphogenesis") -AnnotationAssertion(Annotation( "GOC:mtg_heart") "angiogenesis involved in heart vascular morphogenesis") -AnnotationAssertion(Annotation( "GOC:mtg_heart") "coronary blood vessel angiogenesis") -AnnotationAssertion(Annotation( "GOC:mtg_heart") "coronary vasculature angiogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060978") -AnnotationAssertion(rdfs:label "angiogenesis involved in coronary vascular morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (vasculogenesis involved in coronary vascular morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The differentiation of endothelial cells from progenitor cells that contributes to blood vessel development in the heart, and the de novo formation of blood vessels and tubes.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-06T02:19:42Z") -AnnotationAssertion(Annotation( "GOC:mtg_heart") "coronary vasculogenesis") -AnnotationAssertion(Annotation( "GOC:mtg_heart") "vasculogenesis involved in coronary blood vessel morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060979") -AnnotationAssertion(rdfs:label "vasculogenesis involved in coronary vascular morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cell migration involved in coronary vasculogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The orderly movement of a cell from one site to another that will contribute to the differentiation of an endothelial cell that will form the blood vessels of the heart.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-06T02:33:06Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060980") -AnnotationAssertion(rdfs:label "cell migration involved in coronary vasculogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cell migration involved in coronary angiogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The orderly movement of a cell from one site to another that will contribute to the formation of new blood vessels in the heart from pre-existing blood vessels.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-06T02:49:12Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060981") -AnnotationAssertion(rdfs:label "cell migration involved in coronary angiogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (coronary artery morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which the anatomical structures of coronary arteries are generated and organized. Coronary arteries are blood vessels that transport blood to the heart muscle.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2009-10-06T02:58:52Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060982") -AnnotationAssertion(rdfs:label "coronary artery morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - # Class: (endocrine hormone secretion) AnnotationAssertion(Annotation( "GOC:dph") "The regulated release of a hormone into the circulatory system.") @@ -100546,63 +27012,6 @@ AnnotationAssertion(rdfs:label "endo SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (kidney morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_kidney_jan10") "Morphogenesis of a kidney. A kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-01-19T08:16:55Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060993") -AnnotationAssertion(rdfs:label "kidney morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cell-cell signaling involved in kidney development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_kidney_jan10") "Any process that mediates the transfer of information from one cell to another and contributes to the progression of the kidney over time, from its formation to the mature organ.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-01-19T08:33:40Z") -AnnotationAssertion(Annotation( "GOC:mah") "cell-cell signalling involved in kidney development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0060995") -AnnotationAssertion(rdfs:label "cell-cell signaling involved in kidney development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (pattern specification involved in kidney development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_kidney_jan10") "Any developmental process that results in the creation of defined areas or spaces within the kidney to which cells respond and eventually are instructed to differentiate.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-01-21T09:05:54Z") -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "kidney pattern specification") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "kidney pattern formation") -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "pattern formation involved in kidney development") -AnnotationAssertion( "GO:0061004") -AnnotationAssertion(rdfs:label "pattern specification involved in kidney development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cell differentiation involved in kidney development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the kidney as it progresses from its formation to the mature state.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-01-21T09:13:55Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061005") -AnnotationAssertion(rdfs:label "cell differentiation involved in kidney development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of cell proliferation involved in kidney morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_kidney_jan10") "Any process that modulates the frequency, rate or extent of cell proliferation that contributes to the shaping of the kidney.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-01-21T11:25:23Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061006") -AnnotationAssertion(rdfs:label "regulation of cell proliferation involved in kidney morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (hepaticobiliary system process) AnnotationAssertion(Annotation( "GOC:dph") "An system process carried out by any of the organs or tissues of the hepaticobiliary system. The hepaticobiliary system is responsible for metabolic and catabolic processing of small molecules absorbed from the blood or gut, hormones and serum proteins, detoxification, storage of glycogen, triglycerides, metals and lipid soluble vitamins and excretion of bile. Included are the synthesis of albumin, blood coagulation factors, complement, and specific binding proteins.") @@ -100615,176 +27024,6 @@ AnnotationAssertion( "hepaticobiliary system process") SubClassOf( ) -# Class: (hepaticobiliary system development) - -AnnotationAssertion(Annotation( "GOC:dph") "The progression of the hepaticobiliary system over time, from its formation to the mature structure. The hepaticobiliary system is responsible for metabolic and catabolic processing of small molecules absorbed from the blood or gut, hormones and serum proteins, detoxification, storage of glycogen, triglycerides, metals and lipid soluble vitamins and excretion of bile. Included are the synthesis of albumin, blood coagulation factors, complement, and specific binding proteins.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-01-22T09:11:59Z") -AnnotationAssertion(Annotation( "GOC:dph") "hepatobiliary system development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061008") -AnnotationAssertion(rdfs:label "hepaticobiliary system development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (common bile duct development) - -AnnotationAssertion(Annotation( "PMID:20614624") "The progression of the common bile duct over time, from its formation to the mature structure. The common bile duct is formed from the joining of the common hepatic duct running from the liver, and the cystic duct running from the gallbladder. The common bile duct transports bile from the liver and gallbladder to the intestine.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-01-22T09:17:13Z") -AnnotationAssertion(Annotation( "PMID:20614624") "EHBD development") -AnnotationAssertion(Annotation( "PMID:20614624") "extrahepatic bile duct development") -AnnotationAssertion(Annotation( "PMID:20614624") "CBD development") -AnnotationAssertion(Annotation( "GOC:dph") "bile duct development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061009") -AnnotationAssertion(rdfs:label "common bile duct development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (gallbladder development) - -AnnotationAssertion(Annotation( "GOC:dph") "The progression of the gallbladder over time, from its initial formation to the mature structure. The gallbladder is a cavitated organ that stores bile.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-01-22T09:38:44Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061010") -AnnotationAssertion(rdfs:label "gallbladder development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (hepatic duct development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:20614624") "The progression of the hepatic duct over time, from its formation to the mature structure. The hepatic duct is the duct that leads from the liver to the common bile duct.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-01-22T09:44:39Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061011") -AnnotationAssertion(rdfs:label "hepatic duct development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (hepatoblast differentiation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:15226394") "The process in which a relatively unspecialized cell acquires specialized features of a hepatoblast. A hepatoblast is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into hepatocytes and cholangiocytes.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-02-02T09:08:03Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061017") -AnnotationAssertion(rdfs:label "hepatoblast differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (membrane organization) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "A process which results in the assembly, arrangement of constituent parts, or disassembly of a membrane. A membrane is a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.") -AnnotationAssertion( "jl") -AnnotationAssertion( "2010-02-08T02:43:11Z") -AnnotationAssertion( "GO:0016044") -AnnotationAssertion( "GO:0044802") -AnnotationAssertion( "cellular membrane organisation") -AnnotationAssertion( "cellular membrane organization") -AnnotationAssertion(Annotation( "GOC:mah") "membrane organisation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:mah") "membrane organization and biogenesis") -AnnotationAssertion( "single-organism membrane organization") -AnnotationAssertion( "GO:0061024") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "membrane organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (membrane fusion) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "The membrane organization process that joins two lipid bilayers to form a single membrane.") -AnnotationAssertion( "jl") -AnnotationAssertion( "2010-02-08T02:48:06Z") -AnnotationAssertion( "GO:0006944") -AnnotationAssertion( "GO:0044801") -AnnotationAssertion( "Wikipedia:Lipid_bilayer_fusion") -AnnotationAssertion( "cellular membrane fusion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "single-organism membrane fusion") -AnnotationAssertion( "GO:0061025") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "membrane fusion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (umbilical cord development) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") "The process whose specific outcome is the development of the umbilical cord, from its formation to the mature structure. The umbilical cord is an organ or embryonic origin consisting of the 2 umbilical arteries and the one umbilical vein. The umbilical cord connects the cardiovascular system of the fetus to the mother via the placenta.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-02-09T09:09:22Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061027") -AnnotationAssertion(rdfs:label "umbilical cord development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (eyelid development in camera-type eye) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:yaf") "The progression of the eyelid in a camera-type eye from its formation to the mature state. The eyelid is a membranous cover that helps protect and lubricate the eye.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-02-09T09:36:11Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061029") -AnnotationAssertion(rdfs:label "eyelid development in camera-type eye") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (epithelial cell differentiation involved in mammary gland alveolus development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:yaf") "The process in which a relatively unspecialized epithelial cell becomes a more specialized epithelial cell of the mammary gland alveolus.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-02-09T09:43:00Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061030") -AnnotationAssertion(rdfs:label "epithelial cell differentiation involved in mammary gland alveolus development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (visceral serous pericardium development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:yaf") "The progression of the visceral serous pericardium from its formation to the mature structure. The visceral serous pericardium is the inner layer of the pericardium.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-02-09T09:52:49Z") -AnnotationAssertion(Annotation( "GOC:dph") "epicardium development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061032") -AnnotationAssertion(rdfs:label "visceral serous pericardium development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (olfactory bulb mitral cell layer development) - -AnnotationAssertion(Annotation( "GOC:dph") "The progression of the olfactory bulb mitral cell layer over time from its initial formation until its mature state. The mitral cell layer is composed of pyramidal neurons whose cell bodies are located between the granule cell layer and the plexiform layer.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-02-09T03:30:23Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061034") -AnnotationAssertion(rdfs:label "olfactory bulb mitral cell layer development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (regulation of cartilage development) AnnotationAssertion(Annotation( "GOC:dph") "Any process that modulates the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.") @@ -100793,22 +27032,8 @@ AnnotationAssertion( AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0061035") AnnotationAssertion(rdfs:label "regulation of cartilage development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (positive regulation of cartilage development) - -AnnotationAssertion(Annotation( "GOC:dph") "Any process that increases the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-02-09T03:41:35Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061036") -AnnotationAssertion(rdfs:label "positive regulation of cartilage development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - # Class: (negative regulation of cartilage development) AnnotationAssertion(Annotation( "GOC:dph") "Any process that decreases the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.") @@ -100817,583 +27042,10 @@ AnnotationAssertion( AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0061037") AnnotationAssertion(rdfs:label "negative regulation of cartilage development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ) -# Class: (uterus morphogenesis) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") "The process in which anatomical structures of the uterus are generated and organized.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-02-22T11:12:35Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061038") -AnnotationAssertion(rdfs:label "uterus morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (female gonad morphogenesis) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") "The process in which a female gonad is generated and organized.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-02-22T11:29:28Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "ovary morphogenesis") -AnnotationAssertion( "GO:0061040") -AnnotationAssertion(rdfs:label "female gonad morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (regulation of wound healing) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") "Any process that modulates the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-02-25T10:14:37Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061041") -AnnotationAssertion(rdfs:label "regulation of wound healing") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (negative regulation of wound healing) - -AnnotationAssertion(Annotation( "GOC:dph") "Any process that decreases the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-02-25T10:33:30Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061045") -AnnotationAssertion(rdfs:label "negative regulation of wound healing") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of branching involved in lung morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:yaf") "Any process that modulates the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-02-25T10:41:38Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061046") -AnnotationAssertion(rdfs:label "regulation of branching involved in lung morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of branching involved in lung morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:yaf") "Any process that increases the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-02-25T10:50:01Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061047") -AnnotationAssertion(rdfs:label "positive regulation of branching involved in lung morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of branching involved in lung morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:yaf") "Any process that decreases the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-02-25T10:51:31Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061048") -AnnotationAssertion(rdfs:label "negative regulation of branching involved in lung morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cell growth involved in cardiac muscle cell development) - -AnnotationAssertion(Annotation( "GOC:dph") "The growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-02-25T12:56:07Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") "cardiac muscle cell hypertrophy") -AnnotationAssertion(Annotation( "GOC:dph") "cardiomyocyte growth") -AnnotationAssertion(Annotation( "GOC:dph") "heart muscle cell growth") -AnnotationAssertion( "GO:0061049") -AnnotationAssertion(rdfs:label "cell growth involved in cardiac muscle cell development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (regulation of cell growth involved in cardiac muscle cell development) - -AnnotationAssertion(Annotation( "GOC:dph") "Any process that modulates the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-02-25T01:05:16Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061050") -AnnotationAssertion(rdfs:label "regulation of cell growth involved in cardiac muscle cell development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of cell growth involved in cardiac muscle cell development) - -AnnotationAssertion(Annotation( "GOC:dph") "Any process that increases the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-02-25T01:08:08Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061051") -AnnotationAssertion(rdfs:label "positive regulation of cell growth involved in cardiac muscle cell development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of cell growth involved in cardiac muscle cell development) - -AnnotationAssertion(Annotation( "GOC:dph") "Any process that decreases the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-02-25T01:11:30Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061052") -AnnotationAssertion(rdfs:label "negative regulation of cell growth involved in cardiac muscle cell development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (somite development) - -AnnotationAssertion(Annotation( "GOC:dph") "The progression of a somite from its initial formation to the mature structure. Somites are mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-03-02T12:05:13Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061053") -AnnotationAssertion(rdfs:label "somite development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (dermatome development) - -AnnotationAssertion(Annotation( "GOC:dph") "The progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-03-02T12:07:37Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061054") -AnnotationAssertion(rdfs:label "dermatome development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (myotome development) - -AnnotationAssertion(Annotation( "GOC:dph") "The progression of the myotome over time, from its formation to the mature structure. The myotome is the portion of the somite that will give rise to muscle.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-03-02T12:11:01Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061055") -AnnotationAssertion(rdfs:label "myotome development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (sclerotome development) - -AnnotationAssertion(Annotation( "GOC:dph") "The progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-03-02T12:12:40Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061056") -AnnotationAssertion(rdfs:label "sclerotome development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (muscle structure development) - -AnnotationAssertion(Annotation( "GOC:dph") "The progression of a muscle structure over time, from its formation to its mature state. Muscle structures are contractile cells, tissues or organs that are found in multicellular organisms.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-03-09T08:55:14Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061061") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "muscle structure development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - -# Class: (regulation of nematode larval development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:kmv") "Any process that modulates the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-03-11T12:59:21Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061062") -AnnotationAssertion(rdfs:label "regulation of nematode larval development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (positive regulation of nematode larval development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:kmv") "Any process that increases the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-03-11T01:03:34Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061063") -AnnotationAssertion(rdfs:label "positive regulation of nematode larval development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of nematode larval development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:kmv") "Any process that decreases the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-03-11T01:04:39Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061064") -AnnotationAssertion(rdfs:label "negative regulation of nematode larval development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (urethra development) - -AnnotationAssertion(Annotation( "GOC:dph") "The progression of the urethra over time from its initial formation to the mature structure. The urethra is a renal system organ that carries urine from the bladder to outside the body.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-03-12T08:24:52Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061068") -AnnotationAssertion(rdfs:label "urethra development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (male urethra development) - -AnnotationAssertion(Annotation( "GOC:dph") "The progression of the male urethra over time from its initial formation to the mature structure. The male urethra is a renal system organ that carries urine from the bladder through the penis to outside the body.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-03-12T08:28:19Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061069") -AnnotationAssertion(rdfs:label "male urethra development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (female urethra development) - -AnnotationAssertion(Annotation( "GOC:dph") "The progression of the female urethra over time from its initial formation to the mature structure. The female urethra is a renal system organ that carries urine from the bladder to outside the body, exiting above the vaginal opening.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-03-12T08:29:43Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061070") -AnnotationAssertion(rdfs:label "female urethra development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (urethra epithelium development) - -AnnotationAssertion(Annotation( "GOC:dph") "The progression of the urethra epithelium over time from its initial formation to the mature structure. The urethra is a renal system organ that carries urine from the bladder to outside the body. The epithelium is the tubular, planar layer of cells through which the urine passes.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-03-12T08:36:53Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061071") -AnnotationAssertion(rdfs:label "urethra epithelium development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (iris morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") "The process in which the iris is generated and organized. The iris is an anatomical structure in the eye whose opening forms the pupil. The iris is responsible for controlling the diameter and size of the pupil and the amount of light reaching the retina.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-03-16T10:48:42Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061072") -AnnotationAssertion(rdfs:label "iris morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (ciliary body morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") "The process in which the ciliary body generated and organized. The ciliary body is the circumferential tissue inside the eye composed of the ciliary muscle and ciliary processes.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-03-16T10:55:19Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061073") -AnnotationAssertion(rdfs:label "ciliary body morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (regulation of neural retina development) - -AnnotationAssertion(Annotation( "GOC:dph") "Any process that modulates the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-03-16T11:47:05Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061074") -AnnotationAssertion(rdfs:label "regulation of neural retina development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of neural retina development) - -AnnotationAssertion(Annotation( "GOC:dph") "Any process that increases the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-03-16T11:59:48Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061075") -AnnotationAssertion(rdfs:label "positive regulation of neural retina development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (negative regulation of neural retina development) - -AnnotationAssertion(Annotation( "GOC:dph") "Any process that decreases the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-03-16T12:46:11Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061076") -AnnotationAssertion(rdfs:label "negative regulation of neural retina development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (left horn of sinus venosus development) - -AnnotationAssertion(Annotation( "GOC:dph") "The progression of the left horn of the sinus venosus from its initial formation to the mature structure.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-04-08T02:40:27Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061079") -AnnotationAssertion(rdfs:label "left horn of sinus venosus development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (right horn of sinus venosus development) - -AnnotationAssertion(Annotation( "GOC:dph") "The progression of the right horn of the sinus venosus from its formation to the mature structure.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-04-08T02:45:10Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061080") -AnnotationAssertion(rdfs:label "right horn of sinus venosus development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (positive regulation of myeloid leukocyte cytokine production involved in immune response) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") "Any process that modulates the rate, frequency, or extent of the production of a cytokine that contributes to the immune response.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-04-13T11:26:41Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") "positive regulation of myeloid cell cytokine production involved in immune response") -AnnotationAssertion( "GO:0061081") -AnnotationAssertion(rdfs:label "positive regulation of myeloid leukocyte cytokine production involved in immune response") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (myeloid leukocyte cytokine production) - -AnnotationAssertion(Annotation( "GOC:dph") "Any process that contributes to cytokine production by a myeloid cell.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-04-13T11:29:42Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061082") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.") -AnnotationAssertion(rdfs:label "myeloid leukocyte cytokine production") -SubClassOf( ) - -# Class: (regulation of protein tyrosine kinase activity) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the rate, frequency, or extent of protein tyrosine kinase activity.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-04-26T02:34:53Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061097") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "regulation of protein tyrosine kinase activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of protein tyrosine kinase activity) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that increases the rate, frequency, or extent of protein tyrosine kinase activity.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-04-26T02:34:53Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061098") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "positive regulation of protein tyrosine kinase activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (negative regulation of protein tyrosine kinase activity) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that decreases the rate, frequency, or extent of protein tyrosine kinase activity.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-04-26T02:34:53Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061099") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "negative regulation of protein tyrosine kinase activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (lung neuroendocrine cell differentiation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:9126746") "The process in which a relatively unspecialized cell acquires specialized features of a neuroendocrine cell of the lung epithelium.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-04-27T03:28:46Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061100") -AnnotationAssertion(rdfs:label "lung neuroendocrine cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (neuroendocrine cell differentiation) - -AnnotationAssertion(Annotation( "GOC:dph") "The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a neuroendocrine cell. A neuroendocrine cell is a cell that receives input form a neuron which controls the secretion of an endocrine substance.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-04-28T09:42:20Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061101") -AnnotationAssertion(rdfs:label "neuroendocrine cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (stomach neuroendocrine cell differentiation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:18173746") "The process in which a relatively unspecialized cell acquires specialized features of a neuroendocrine cell of the stomach epithelium.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-04-28T09:47:07Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") "gastric neuroendocrine cell differentiation") -AnnotationAssertion( "GO:0061102") -AnnotationAssertion(rdfs:label "stomach neuroendocrine cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (adrenal chromaffin cell differentiation) - -AnnotationAssertion(Annotation( "GOC:dph") "The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of an adrenal chromaffin cell. An adrenal chromaffin cell is a neuroendocrine cell that stores epinephrine secretory vesicles.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-04-29T08:27:53Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061104") -AnnotationAssertion(rdfs:label "adrenal chromaffin cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (regulation of stomach neuroendocrine cell differentiation) - -AnnotationAssertion(Annotation( "GOC:dph") "Any process that modulates the rate, frequency or extent of the differentiation of a neuroendocrine cell in the stomach.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-04-29T12:19:37Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061105") -AnnotationAssertion(rdfs:label "regulation of stomach neuroendocrine cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of stomach neuroendocrine cell differentiation) - -AnnotationAssertion(Annotation( "GOC:dph") "Any process that decreases the rate, frequency or extent of the differentiation of a neuroendocrine cell in the stomach.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-04-29T12:23:05Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061106") -AnnotationAssertion(rdfs:label "negative regulation of stomach neuroendocrine cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (seminal vesicle development) - -AnnotationAssertion(Annotation( "GOC:dph") "The progression of the seminal vesicle over time, from its formation to the mature structure. The seminal vesicle is a gland that contributes to the production of semen.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-04-30T10:17:30Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061107") -AnnotationAssertion(rdfs:label "seminal vesicle development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (seminal vesicle epithelium development) - -AnnotationAssertion(Annotation( "GOC:dph") "The progression of the seminal vesicle epithelium over time, from its formation to the mature structure.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-04-30T10:19:54Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061108") -AnnotationAssertion(rdfs:label "seminal vesicle epithelium development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (dense core granule organization) - -AnnotationAssertion(Annotation( "GOC:dph") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a dense core granule. A dense core granule is a secretory organelle found in endocrine cells.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-05-01T09:34:37Z") -AnnotationAssertion(Annotation( "GOC:mah") "dense core granule organisation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061109") -AnnotationAssertion(rdfs:label "dense core granule organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (pancreas morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") "Morphogenesis of the pancreas. Morphogenesis is the process in which anatomical structures are generated and organized.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-05-05T11:55:30Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061113") -AnnotationAssertion(rdfs:label "pancreas morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (branching involved in pancreas morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") "The process in which the branches of the pancreas are generated and organized.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-05-05T12:03:04Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061114") -AnnotationAssertion(rdfs:label "branching involved in pancreas morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of heart growth) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:hjd") "Any process that decreases the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-05-17T07:31:28Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061117") -AnnotationAssertion(rdfs:label "negative regulation of heart growth") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (pancreatic bud formation) - -AnnotationAssertion(Annotation( "GOC:dph") "The morphogenetic process in which the foregut region specified to become the pancreas forms a bud.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-05-17T09:33:40Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061130") -AnnotationAssertion(rdfs:label "pancreatic bud formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - # Class: (morphogenesis of a branching epithelium) AnnotationAssertion(Annotation( "GOC:dph") "The process in which the anatomical structures of a branched epithelium are generated and organized.") @@ -101405,1536 +27057,6 @@ AnnotationAssertion(rdfs:label "morp SubClassOf( ) SubClassOf( ) -# Class: (lung secretory cell differentiation) - -AnnotationAssertion(Annotation( "GOC:dph") "The process in which a relatively unspecialized cell acquires specialized features of a lung secretory cell. A lung secretory cell is a specialized epithelial cell of the lung that contains large secretory granules in its apical part.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-05-25T09:28:53Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061140") -AnnotationAssertion(rdfs:label "lung secretory cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (lung ciliated cell differentiation) - -AnnotationAssertion(Annotation( "GOC:cilia") Annotation( "GOC:dph") Annotation( "GOC:krc") "The process in which a relatively unspecialized cell acquires specialized features of a lung ciliated cell. A lung ciliated cell is a specialized lung epithelial cell that contains cilia for moving substances released from lung secretory cells.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-05-25T09:31:14Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061141") -AnnotationAssertion(rdfs:label "lung ciliated cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (alveolar primary septum development) - -AnnotationAssertion(Annotation( "GOC:dph") "The progression of a primary alveolar septum over time, from its formation to the mature structure. A primary alveolar septum is a specialized epithelium that surrounds the saccule as it forms.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-05-25T10:21:27Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061143") -AnnotationAssertion(rdfs:label "alveolar primary septum development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (alveolar secondary septum development) - -AnnotationAssertion(Annotation( "GOC:dph") "The progression of a secondary alveolar septum over time, from its formation to the mature structure. A secondary alveolar septum is a specialized epithelium that subdivides the initial saccule.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-05-25T10:43:55Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061144") -AnnotationAssertion(rdfs:label "alveolar secondary septum development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (Peyer's patch morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") "The process in which a Peyer's patch is generated and organized. Peyer's patches are typically found as nodules associated with gut epithelium with distinct internal structures including B- and T-zones for the activation of lymphocytes.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-05-26T06:46:23Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061146") -AnnotationAssertion(rdfs:label "Peyer's patch morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (endocardial endothelium development) - -AnnotationAssertion(Annotation( "GOC:dph") "The progression of the endocardial endothelium over time, from its initial formation to the mature structure. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-06-03T09:15:31Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061147") -AnnotationAssertion(rdfs:label "endocardial endothelium development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (extracellular matrix organization involved in endocardium development) - -AnnotationAssertion(Annotation( "GOC:dph") "A process which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix of the endocardium. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-06-03T09:18:02Z") -AnnotationAssertion(Annotation( "GOC:mah") "extracellular matrix organisation involved in endocardium development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061148") -AnnotationAssertion(rdfs:label "extracellular matrix organization involved in endocardium development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (trachea submucosa development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:yaf") "The progression of the trachea submucosa over time from its formation to the mature structure. The trachea submucosa is made up of the glands and elastic tissue that lie under the mucosa in the trachea.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-06-07T09:58:40Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061152") -AnnotationAssertion(rdfs:label "trachea submucosa development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (trachea gland development) - -AnnotationAssertion(Annotation( "GOC:dph") "The progression of a trachea gland over time, from its formation to the mature structure. Trachea glands are found under the mucus of the trachea and secrete mucus, and agents that help protect the lung from injury and infection.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-06-07T10:10:51Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061153") -AnnotationAssertion(rdfs:label "trachea gland development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (endothelial tube morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:yaf") "The process in which the anatomical structures of a tube are generated and organized from an endothelium. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-06-15T09:05:00Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061154") -AnnotationAssertion(rdfs:label "endothelial tube morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (pulmonary artery endothelial tube morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:yaf") "The process in which the anatomical structures of a tube are generated and organized from the pulmonary artery endothelium. An pulmonary artery endothelium is an epithelium that lines the pulmonary artery.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-06-15T09:09:04Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061155") -AnnotationAssertion(rdfs:label "pulmonary artery endothelial tube morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (pulmonary artery morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:yaf") "The process in which the anatomical structures of the pulmonary artery are generated and organized. The pulmonary artery is the artery that carries blood from the heart to the lungs.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-06-15T09:13:47Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061156") -AnnotationAssertion(rdfs:label "pulmonary artery morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of hair follicle placode formation) - -AnnotationAssertion(Annotation( "GOC:dph") "Any process that modulates the rate, frequency, or extent of hair follicle placode formation, the developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-06-25T01:03:29Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061168") -AnnotationAssertion(rdfs:label "regulation of hair follicle placode formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of hair placode formation) - -AnnotationAssertion(Annotation( "GOC:dph") "Any process that increases the rate, frequency, or extent of hair follicle placode formation, the developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-06-25T01:08:50Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061169") -AnnotationAssertion(rdfs:label "positive regulation of hair placode formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of hair follicle placode formation) - -AnnotationAssertion(Annotation( "GOC:dph") "Any process that decreases the rate, frequency, or extent of hair follicle placode formation, the developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-06-25T01:10:48Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061170") -AnnotationAssertion(rdfs:label "negative regulation of hair follicle placode formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (regulation of insulin secretion involved in cellular response to glucose stimulus) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") "Any process that modulates the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-07-13T09:38:42Z") -AnnotationAssertion(Annotation( "GOC:dph") "regulation of insulin secretion in response to glucose") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061178") -AnnotationAssertion(rdfs:label "regulation of insulin secretion involved in cellular response to glucose stimulus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (negative regulation of insulin secretion involved in cellular response to glucose stimulus) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") "Any process that decreases the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-07-13T09:41:46Z") -AnnotationAssertion(Annotation( "GOC:bf") "negative regulation of insulin secretion involved in cellular response to glucose") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") "negative regulation of insulin secretion in response to glucose") -AnnotationAssertion( "GO:0061179") -AnnotationAssertion(rdfs:label "negative regulation of insulin secretion involved in cellular response to glucose stimulus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (mammary gland epithelium development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:yaf") "The process whose specific outcome is the progression of the mammary gland epithelium over time, from its formation to the mature structure. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-07-14T08:18:24Z") -AnnotationAssertion(Annotation( "GOC:dph") "breast epithelium development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061180") -AnnotationAssertion(rdfs:label "mammary gland epithelium development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (regulation of chondrocyte development) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") "Any process that modulates the rate, frequency, or extent of the process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-07-14T08:28:52Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061181") -AnnotationAssertion(rdfs:label "regulation of chondrocyte development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of chondrocyte development) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") "Any process that decreases the rate, frequency, or extent of the process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-07-14T08:33:05Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061182") -AnnotationAssertion(rdfs:label "negative regulation of chondrocyte development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of dermatome development) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") "Any process that modulates the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-07-14T08:40:26Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061183") -AnnotationAssertion(rdfs:label "regulation of dermatome development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of dermatome development) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") "Any process that increases the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-07-14T08:42:03Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061184") -AnnotationAssertion(rdfs:label "positive regulation of dermatome development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (negative regulation of dermatome development) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") "Any process that decreases the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-07-14T08:43:08Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061185") -AnnotationAssertion(rdfs:label "negative regulation of dermatome development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (positive regulation of sclerotome development) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") "Any process that increases the rate, frequency, or extent of the progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-07-14T09:17:23Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061189") -AnnotationAssertion(rdfs:label "positive regulation of sclerotome development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of sclerotome development) - -AnnotationAssertion(Annotation( "GOC:dph") "Any process that modulates the rate, frequency, or extent of the progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-07-14T09:19:47Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061190") -AnnotationAssertion(rdfs:label "regulation of sclerotome development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (taste bud development) - -AnnotationAssertion(Annotation( "GOC:dph") "The progression of the taste bud over time, from its formation to the mature state. The taste bud is a specialized area of the tongue that contains taste receptors.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-07-27T10:55:08Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061193") -AnnotationAssertion(rdfs:label "taste bud development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (taste bud morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") "The process in which the anatomical structures of the taste bud are generated and organized. The taste bud is a specialized area of the tongue that contains taste receptors.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-07-27T11:01:31Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061194") -AnnotationAssertion(rdfs:label "taste bud morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (taste bud formation) - -AnnotationAssertion(Annotation( "GOC:dph") "The developmental process pertaining to the initial formation of the taste bud from unspecified parts. The taste bud is a specialized area of the tongue that contains taste receptors.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-07-27T12:22:26Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061195") -AnnotationAssertion(rdfs:label "taste bud formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (fungiform papilla development) - -AnnotationAssertion(Annotation( "GOC:dph") "The progression of the fungiform papilla over time, from its formation to the mature structure. The fungiform papilla is a mushroom-shaped papilla of the tongue.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-07-27T12:23:48Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061196") -AnnotationAssertion(rdfs:label "fungiform papilla development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (fungiform papilla morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") "The process in which the anatomical structures of the fungiform papilla are generated and organized. The fungiform papilla is a mushroom-shaped papilla of the tongue.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-07-27T12:26:40Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061197") -AnnotationAssertion(rdfs:label "fungiform papilla morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (fungiform papilla formation) - -AnnotationAssertion(Annotation( "GOC:dph") "The developmental process pertaining to the initial formation of a spongiform papilla from unspecified parts. The fungiform papilla is a mushroom-shaped papilla of the tongue.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-07-27T12:29:03Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061198") -AnnotationAssertion(rdfs:label "fungiform papilla formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (paramesonephric duct development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:yaf") "The process whose specific outcome is the progression of the paramesonephric duct over time, from its formation to the mature structure. Mullerian ducts (or paramesonephric ducts) are paired ducts of the embryo that run down the lateral sides of the urogenital ridge and terminate at the mullerian eminence in the primitive urogenital sinus. In the female, they will develop to form the fallopian tubes, uterus, cervix, and the upper portion of the vagina; in the male, they are lost. These ducts are made of tissue of mesodermal origin.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-07-30T10:54:47Z") -AnnotationAssertion(Annotation( "GOC:dph") "Mullerian duct development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061205") -AnnotationAssertion(rdfs:label "paramesonephric duct development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (mesonephros morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the anatomical structures of the mesonephros are generated and organized.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-08-17T03:11:10Z") -AnnotationAssertion(Annotation( "GOC:dph") "Wolffian body morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061206") -AnnotationAssertion(rdfs:label "mesonephros morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cell differentiation involved in mesonephros development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the mesonephros as it progresses from its formation to the mature state.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-08-17T03:21:23Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061208") -AnnotationAssertion(rdfs:label "cell differentiation involved in mesonephros development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cell proliferation involved in mesonephros development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The multiplication or reproduction of cells, resulting in the expansion of the population in the mesonephros.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-08-17T03:22:46Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061209") -AnnotationAssertion(rdfs:label "cell proliferation involved in mesonephros development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cell-cell signaling involved in mesonephros development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "Any process that mediates the transfer of information from one cell to another and contributes to the progression of the mesonephros over time, from its formation to the mature organ.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-08-17T03:24:08Z") -AnnotationAssertion(Annotation( "GOC:mah") "cell-cell signalling involved in mesonephros development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061210") -AnnotationAssertion(rdfs:label "cell-cell signaling involved in mesonephros development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (mesonephric collecting duct development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of a collecting duct in the mesonephros over time, from its formation to the mature structure. The collecting duct regulates water, electrolyte and acid-base balance. The collecting duct is the final common path through which urine flows before entering the ureter and then emptying into the bladder.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-08-17T03:25:51Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061211") -AnnotationAssertion(rdfs:label "mesonephric collecting duct development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (mesonephric juxtaglomerular apparatus development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the juxtaglomerular apparatus in the mesonephros over time, from its formation to the mature structure. The juxtaglomerular apparatus is an anatomical structure which consists of juxtaglomerular cells, extraglomerular mesangial cells and the macula densa. The juxtaglomerular apparatus lies adjacent to the glomerulus and regulates kidney function by maintaining the blood flow to the kidney and the filtration rate.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-08-17T03:27:36Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061212") -AnnotationAssertion(rdfs:label "mesonephric juxtaglomerular apparatus development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (positive regulation of mesonephros development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "Any process that increases the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-08-17T03:39:35Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061213") -AnnotationAssertion(rdfs:label "positive regulation of mesonephros development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (mesonephric smooth muscle tissue development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of smooth muscle in the mesonephros over time, from its formation to the mature structure.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-08-17T03:29:54Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061214") -AnnotationAssertion(rdfs:label "mesonephric smooth muscle tissue development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (mesonephric nephron development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of a nephron in the mesonephros over time, from its formation to the mature structure. A nephron is the functional unit of the kidney.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-08-17T03:31:08Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061215") -AnnotationAssertion(rdfs:label "mesonephric nephron development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (regulation of mesonephros development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "Any process that modulates the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-08-17T03:35:31Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061217") -AnnotationAssertion(rdfs:label "regulation of mesonephros development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of mesonephros development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "Any process that decreases the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-08-17T03:43:06Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061218") -AnnotationAssertion(rdfs:label "negative regulation of mesonephros development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (mesonephric mesenchyme development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The biological process whose specific outcome is the progression of a mesonephric mesenchyme from an initial condition to its mature state. This process begins with the formation of mesonephric mesenchyme and ends with the mature structure. Mesonephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the mesonephros.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-08-17T03:45:44Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061219") -AnnotationAssertion(rdfs:label "mesonephric mesenchyme development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (mesonephric macula densa development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the mesonephric macula densa over time, from its formation to the mature structure. The mesonephric macula densa is an area of specialized cells in the distal tubule of the mesonephros that makes contact with the vascular pole of the glomerulus.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-08-19T01:11:41Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061220") -AnnotationAssertion(rdfs:label "mesonephric macula densa development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (mesonephric mesenchyme morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the anatomical structures of a mesonephric mesenchymal tissue are generated and organized. Mesonephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the mesonephros.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-08-19T01:17:38Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061221") -AnnotationAssertion(rdfs:label "mesonephric mesenchyme morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (mesonephric glomerulus development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The progression of the mesonephric glomerulus over time from its initial formation until its mature state. The mesonephric glomerulus is a capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the mature vertebrate kidney, or mesonephros.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-08-19T01:26:00Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061224") -AnnotationAssertion(rdfs:label "mesonephric glomerulus development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (pattern specification involved in mesonephros development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "Any developmental process that results in the creation of defined areas or spaces within the mesonephros to which cells respond and eventually are instructed to differentiate.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-08-19T02:22:22Z") -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "mesonephros pattern specification") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "mesonephros pattern formation") -AnnotationAssertion( "GO:0061227") -AnnotationAssertion(rdfs:label "pattern specification involved in mesonephros development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (mesonephric nephron morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the anatomical structures of the mesonephric nephron are generated and organized. A mesonephric nephron is the functional unit of the mesonephros.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-08-19T02:26:24Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061228") -AnnotationAssertion(rdfs:label "mesonephric nephron morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (mesonephric glomerulus vasculature development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The biological process whose specific outcome is the progression of a mesonephric glomerulus vasculature from an initial condition to its mature state. This process begins with the formation of the mesonephric glomerulus vasculature and ends with the mature structure. The mesonephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the mesonephric glomerulus.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-08-19T02:47:06Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061231") -AnnotationAssertion(rdfs:label "mesonephric glomerulus vasculature development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (mesonephric glomerular epithelium development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the mesonephric glomerular epithelium over time, from its formation to the mature structure. The mesonephric glomerular epithelium is an epithelial tissue that covers the outer surfaces of the glomerulus in the mesonephros. The mesonephric glomerular epithelium consists of both parietal and visceral epithelium. Mesonephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the mesonephros.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-08-19T02:49:46Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061232") -AnnotationAssertion(rdfs:label "mesonephric glomerular epithelium development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (mesonephric glomerulus morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the anatomical structures of the mesonephric glomerulus are generated and organized. The mesonephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate mesonephros.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-08-19T02:53:35Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061234") -AnnotationAssertion(rdfs:label "mesonephric glomerulus morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which an organism retains a population of mesenchymal stem cells that contributes to the shaping of a nephron in the mesonephros. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-08-19T02:57:11Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061235") -AnnotationAssertion(rdfs:label "mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (mesonephric comma-shaped body morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the mesonephric comma-shaped body is generated and organized. The mesonephric comma-shaped body is the precursor structure to the mesonephric S-shaped body that contributes to the morphogenesis of a nephron in the mesonephros.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-08-19T03:00:21Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061236") -AnnotationAssertion(rdfs:label "mesonephric comma-shaped body morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (mesonephric nephron tubule morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the anatomical structures of a mesonephric nephron tubule are generated and organized. A mesonephric nephron tubule is an epithelial tube that is part of the mesonephric nephron, the functional part of the mesonephros.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-08-19T03:09:26Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061240") -AnnotationAssertion(rdfs:label "mesonephric nephron tubule morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (mesonephric nephron epithelium development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the mesonephric nephron epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The mesonephric nephron epithelium is a tissue that covers the surface of a nephron in the mesonephros.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-08-19T03:11:59Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061241") -AnnotationAssertion(rdfs:label "mesonephric nephron epithelium development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (mesonephric nephron tubule development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The progression of a mesonephric nephron tubule over time, from its initial formation to the mature structure. A mesonephric nephron tubule is an epithelial tube that is part of the mesonephric nephron, the functional part of the mesonephros.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-08-19T03:17:00Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061242") -AnnotationAssertion(rdfs:label "mesonephric nephron tubule development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (mesonephric renal vesicle morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the anatomical structures of the mesonephric renal vesicle are generated and organized. The renal vesicle is the primordial structure of the mesonephric nephron epithelium, and is formed by the condensation of mesenchymal cells.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-08-19T03:20:21Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061243") -AnnotationAssertion(rdfs:label "mesonephric renal vesicle morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (mesonephric S-shaped body morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the mesonephric S-shaped body is generated and organized. The mesonephric S-shaped body is the successor of the mesonephric comma-shaped body that contributes to the morphogenesis of a nephron in the mesonephros.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-08-19T03:23:55Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061244") -AnnotationAssertion(rdfs:label "mesonephric S-shaped body morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (mesonephric glomerular mesangium development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the mesonephric glomerular mesangium over time, from its formation to the mature structure. The mesonephric glomerular mesangium is the thin membrane connective tissue composed of mesangial cells in the mesonephros, which helps to support the capillary loops in a renal glomerulus.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-08-30T12:59:25Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061247") -AnnotationAssertion(rdfs:label "mesonephric glomerular mesangium development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (mesonephric glomerulus vasculature morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the anatomical structures of the mesonephric glomerulus vasculature are generated and organized. The mesonephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the mesonephric glomerulus.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-08-30T01:11:34Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061248") -AnnotationAssertion(rdfs:label "mesonephric glomerulus vasculature morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (mesonephric glomerular capillary formation) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process that gives rise to a mesonephric glomerular capillary. This process pertains to the initial formation of a structure from unspecified parts.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-08-30T01:17:08Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061249") -AnnotationAssertion(rdfs:label "mesonephric glomerular capillary formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (mesonephric glomerular epithelial cell differentiation) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which a relatively unspecialized cell acquires specialized features of a mesonephric glomerular epithelial cell. Mesonephric glomerular epithelial cells are specialized epithelial cells that form part of the mesonephric glomerulus; there are two types, mesonephric glomerular parietal epithelial cells and mesonephric glomerular visceral epithelial cells.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-08-30T01:20:03Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061250") -AnnotationAssertion(rdfs:label "mesonephric glomerular epithelial cell differentiation") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (mesonephric glomerular epithelial cell development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of a mesonephric glomerular epithelial cell over time, from its formation to the mature structure. Mesonephric glomerular epithelial cells are specialized epithelial cells that form part of the mesonephric glomerulus; there are two types, mesonephric glomerular parietal epithelial cells and mesonephric glomerular visceral epithelial cells.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-08-30T01:20:45Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061251") -AnnotationAssertion(rdfs:label "mesonephric glomerular epithelial cell development") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (mesonephric podocyte differentiation) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which a relatively unspecialized cell acquires specialized features of a mesonephric glomerular visceral epithelial cell. A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the mesonephros.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/23000"^^xsd:anyURI) -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-08-30T02:03:38Z") -AnnotationAssertion( "mesonephric glomerular visceral epithelial cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061256") -AnnotationAssertion(rdfs:label "mesonephric podocyte differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (mesonephric podocyte development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of a mesonephric glomerular visceral epithelial cell over time, from its formation to the mature structure. A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the mesonephros.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/23000"^^xsd:anyURI) -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-08-30T02:10:40Z") -AnnotationAssertion( "mesonephric glomerular visceral epithelial cell development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061257") -AnnotationAssertion(rdfs:label "mesonephric podocyte development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (mesenchymal to epithelial transition involved in mesonephros morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "A transition where a mesenchymal cell establishes apical/basolateral polarity, forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the mesonephros.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-08-30T02:35:15Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "mesonephric mesenchyme to epithelial transition") -AnnotationAssertion( "GO:0061261") -AnnotationAssertion(rdfs:label "mesenchymal to epithelial transition involved in mesonephros morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (mesonephric renal vesicle formation) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The developmental process pertaining to the initial formation of the mesonephros.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-08-30T02:41:20Z") -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "mesonephros formation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061262") -AnnotationAssertion(rdfs:label "mesonephric renal vesicle formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (mesonephric nephron tubule epithelial cell differentiation) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the mesonephric nephron tubule as it progresses from its formation to the mature state.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-08-30T03:02:09Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061265") -AnnotationAssertion(rdfs:label "mesonephric nephron tubule epithelial cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (mesenchymal to epithelial transition involved in mesonephric renal vesicle formation) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the mesonephric renal vesicle.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-08-30T03:26:30Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061271") -AnnotationAssertion(rdfs:label "mesenchymal to epithelial transition involved in mesonephric renal vesicle formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (mesonephric connecting tubule development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the mesonephric connecting tubule over time, from its formation to the mature structure. The mesonephric connecting tubule is a tubular segment of the mesonephric nephron; it connects the distal tubule to the collecting duct in the mesonephros.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-09-02T12:00:56Z") -AnnotationAssertion(Annotation( "GOC:dph") "mesonephric collecting tubule development") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "mesonephric connecting duct development") -AnnotationAssertion( "GO:0061272") -AnnotationAssertion(rdfs:label "mesonephric connecting tubule development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (mesonephric distal tubule morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the anatomical structures of a mesonephric distal tubule are generated and organized. The mesonephric distal tubule is a mesonephric nephron tubule that begins at the macula densa and extends to the mesonephric connecting tubule.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-09-02T12:12:00Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061273") -AnnotationAssertion(rdfs:label "mesonephric distal tubule morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (mesonephric distal tubule development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the mesonephric distal tubule over time, from its formation to the mature structure. The mesonephric distal tubule is a mesonephric nephron tubule that begins at the terminal segment of the proximal tubule and ends at the mesonephric connecting tubule.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-09-02T12:16:25Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061274") -AnnotationAssertion(rdfs:label "mesonephric distal tubule development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (mesonephric proximal tubule development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The progression of the mesonephric proximal tubule over time, from its formation to the mature structure. The mesonephric proximal tubule extends from the capsule to the distal tubule.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-09-02T01:08:05Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061275") -AnnotationAssertion(rdfs:label "mesonephric proximal tubule development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (mesonephric proximal tubule morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the anatomical structures of a mesonephric proximal tubule are generated and organized. The mesonephric proximal tubule extends from the capsule to the distal tubule.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-09-02T01:11:02Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061276") -AnnotationAssertion(rdfs:label "mesonephric proximal tubule morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (mesonephric nephron tubule formation) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The developmental process pertaining to the initial formation of a mesonephric nephron tubule from unspecified parts. A mesonephric nephron tubule is an epithelial tube that is part of a nephron in the mesonephros.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-09-02T01:16:21Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061277") -AnnotationAssertion(rdfs:label "mesonephric nephron tubule formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (epithelial cell migration involved in mesonephric nephron tubule morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The orderly movement of epithelial cells within a renal tubule that contributes to mesonephric nephron tubule morphogenesis.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-09-02T01:18:53Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061278") -AnnotationAssertion(rdfs:label "epithelial cell migration involved in mesonephric nephron tubule morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (epithelial cell migration involved in mesonephric distal tubule morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The orderly movement of epithelial cells within a renal tubule that contributes to mesonephric distal tubule morphogenesis.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-09-02T01:20:56Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061279") -AnnotationAssertion(rdfs:label "epithelial cell migration involved in mesonephric distal tubule morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (epithelial cell migration involved in mesonephric proximal tubule morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The orderly movement of epithelial cells within a renal tubule that contributes to mesonephric proximal tubule morphogenesis.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-09-02T01:23:43Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061280") -AnnotationAssertion(rdfs:label "epithelial cell migration involved in mesonephric proximal tubule morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (mesonephric capsule development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The progression of the mesonephric capsule over time, from its formation to the mature structure. The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-09-02T01:50:06Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061285") -AnnotationAssertion(rdfs:label "mesonephric capsule development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (mesonephric capsule morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the anatomical structures of the mesonephric capsule are generated and organized. The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-09-02T01:53:31Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061286") -AnnotationAssertion(rdfs:label "mesonephric capsule morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (mesonephric capsule formation) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The developmental process pertaining to the initial formation of a mesonephric capsule from unspecified parts. The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-09-02T01:55:03Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061287") -AnnotationAssertion(rdfs:label "mesonephric capsule formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:mtg_kidney_jan10") "Any process that modulates the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the mesonephros.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-09-06T09:48:56Z") -AnnotationAssertion( "regulation of mesenchymal stem cell apoptotic process involved in mesonephric nephron morphogenesis") -AnnotationAssertion( "regulation of mesenchymal stem cell apoptosis involved in mesonephric nephron morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061295") -AnnotationAssertion(rdfs:label "regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:mtg_kidney_jan10") "Any process that reduces the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the mesonephros.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-09-06T09:54:49Z") -AnnotationAssertion( "negative regulation of mesenchymal stem cell apoptotic process involved in mesonephric nephron morphogenesis") -AnnotationAssertion( "negative regulation of mesenchymal stem cell apoptosis involved in mesonephric nephron morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061296") -AnnotationAssertion(rdfs:label "negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (positive regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:mtg_kidney_jan10") "Any process that increases the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the mesonephros.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-09-06T09:58:59Z") -AnnotationAssertion( "positive regulation of mesenchymal stem cell apoptotic process involved in mesonephric nephron morphogenesis") -AnnotationAssertion( "positive regulation of mesenchymal stem cell apoptosis involved in mesonephric nephron morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061297") -AnnotationAssertion(rdfs:label "positive regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (retina vasculature development in camera-type eye) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") "The process whose specific outcome is the progression of the vasculature of the retina over time, from its formation to the mature structure.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-09-06T03:27:06Z") -AnnotationAssertion(Annotation( "GOC:dph") "retinal vasculature development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061298") -AnnotationAssertion(rdfs:label "retina vasculature development in camera-type eye") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (retina vasculature morphogenesis in camera-type eye) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") "The process in which the vasculature of the retina is generated and organized.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-09-06T03:28:25Z") -AnnotationAssertion(Annotation( "GOC:dph") "retinal vasculature morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061299") -AnnotationAssertion(rdfs:label "retina vasculature morphogenesis in camera-type eye") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cerebellum vasculature development) - -AnnotationAssertion(Annotation( "GOC:dph") "The process whose specific outcome is the progression of the vasculature of the cerebellum over time, from its formation to the mature structure.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-09-06T03:36:40Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061300") -AnnotationAssertion(rdfs:label "cerebellum vasculature development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (cerebellum vasculature morphogenesis) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") "The process in which the vasculature of the cerebellum is generated and organized.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-09-06T03:38:05Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061301") -AnnotationAssertion(rdfs:label "cerebellum vasculature morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cornea development in camera-type eye) - -AnnotationAssertion(Annotation( "GOC:dph") "The progression of the cornea over time, from its formation to the mature structure. The cornea is the transparent structure that covers the anterior of the eye.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-09-14T02:09:08Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061303") -AnnotationAssertion(rdfs:label "cornea development in camera-type eye") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (retinal blood vessel morphogenesis) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") "The process whose specific outcome is the progression of a blood vessel of the retina over time, from its formation to the mature structure.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-09-16T09:02:59Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061304") -AnnotationAssertion(rdfs:label "retinal blood vessel morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (cardiac neural crest cell differentiation involved in heart development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_heart") Annotation( "PMID:19705442") "The process in which a relatively unspecialized cell acquires specialized features of a cardiac neural crest cell that will migrate to the heart and contribute to its development. Cardiac neural crest cells are specialized cells that migrate toward the heart from the third, fourth and sixth pharyngeal arches.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-09-23T08:50:56Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061307") -AnnotationAssertion(rdfs:label "cardiac neural crest cell differentiation involved in heart development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (cardiac neural crest cell development involved in heart development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_heart") "The process aimed at the progression of a cardiac neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell that contributes to the development of the heart.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-09-23T09:01:49Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061308") -AnnotationAssertion(rdfs:label "cardiac neural crest cell development involved in heart development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cardiac neural crest cell development involved in outflow tract morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_heart") "The process aimed at the progression of a cardiac neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell that contributes to the shaping of the outflow tract.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-09-23T09:08:37Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061309") -AnnotationAssertion(rdfs:label "cardiac neural crest cell development involved in outflow tract morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cell surface receptor signaling pathway involved in heart development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_heart") Annotation( "GOC:signaling") "The series of molecular signals initiated by a ligand the binding to its receptor on the surface of a cell, which contributes to the progression of the heart over time.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-09-23T09:18:32Z") -AnnotationAssertion(Annotation( "GOC:bf") "cell surface receptor linked signaling pathway involved in heart development") -AnnotationAssertion(Annotation( "GOC:mah") "cell surface receptor linked signalling pathway involved in heart development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061311") -AnnotationAssertion(rdfs:label "cell surface receptor signaling pathway involved in heart development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (renal filtration cell differentiation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_kidney_jan10") "The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a renal filtration cell. Renal filtration cells are specialized cells of the renal system that filter fluids by charge, size or both. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-09-24T12:18:35Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061318") -AnnotationAssertion(rdfs:label "renal filtration cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cell proliferation involved in heart morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_heart") "The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to the shaping of the heart.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-09-28T09:05:26Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061323") -AnnotationAssertion(rdfs:label "cell proliferation involved in heart morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cell proliferation involved in outflow tract morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_heart") "The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to the shaping of the outflow tract.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-09-28T09:29:30Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061325") -AnnotationAssertion(rdfs:label "cell proliferation involved in outflow tract morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (renal tubule development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_kidney_jan10") "The progression of the renal tubule over time from its formation to the mature form. A renal tubule is a tube that filters, re-absorbs and secretes substances to rid an organism of waste and to play a role in fluid homeostasis.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-09-28T12:50:43Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061326") -AnnotationAssertion(rdfs:label "renal tubule development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (epithelial cell proliferation involved in Malpighian tubule morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_kidney_jan10") Annotation( "PMID:19783135") "The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population and contributing to the shaping of a Malpighian tubule.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-09-28T02:01:02Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061331") -AnnotationAssertion(rdfs:label "epithelial cell proliferation involved in Malpighian tubule morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (Malpighian tubule bud morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_kidney_jan10") Annotation( "PMID:19783135") "The morphogenetic process in which a bud forms from the embryonic hindgut tube to form the Malpighian tubule. A bud is a protrusion that forms from the tube by localized changes in cell shape and position.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-09-28T01:39:32Z") -AnnotationAssertion(Annotation( "GOC:dph") "Malpighian tubule formation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061332") -AnnotationAssertion(rdfs:label "Malpighian tubule bud morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (renal tubule morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_kidney_jan10") "The process in which the renal tubule is generated by specification of cell fate, through the maintenance of cell polarity, regulated cell proliferation and morphogenetic cell rearrangements, shape changes and growth. A renal tubule is a tube that filters, re-absorbs and secretes substances to rid an organism of waste and to play a role in fluid homeostasis.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-09-28T01:43:04Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061333") -AnnotationAssertion(rdfs:label "renal tubule morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cell rearrangement involved in Malpighian tubule morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_kidney_jan10") "The movement of an epithelial cell with respect to other epithelial cells that contributes to the shaping of the Malpighian tubule.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-09-28T02:04:05Z") -AnnotationAssertion( "cell migration involved in Malpighian tubule morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061334") -AnnotationAssertion(rdfs:label "cell rearrangement involved in Malpighian tubule morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cell growth involved in Malpighian tubule morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_kidney_jan10") Annotation( "PMID:19783135") "The growth of an epithelial cell dependent on cycles of endoreplication, where growth contributes to the shaping of the Malpighian tubule.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-09-28T02:08:25Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061335") -AnnotationAssertion(rdfs:label "cell growth involved in Malpighian tubule morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cell morphogenesis involved in Malpighian tubule morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_kidney_jan10") Annotation( "PMID:19783135") "The shape change of an epithelial cell from a columnar to squamous cell morphology that contributes to the shaping of the Malpighian tubule.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-09-28T02:11:47Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061336") -AnnotationAssertion(rdfs:label "cell morphogenesis involved in Malpighian tubule morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cardiac conduction) - -AnnotationAssertion(Annotation( "GOC:dph") "Transfer of an organized electrical impulse across the heart to coordinate the contraction of cardiac muscles. The process begins with generation of an action potential (in the sinoatrial node (SA) in humans) and ends with a change in the rate, frequency, or extent of the contraction of the heart muscles.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-09-29T08:46:05Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061337") -AnnotationAssertion(rdfs:label "cardiac conduction") -SubClassOf( ) - -# Class: (cell adhesion involved in heart morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_heart") Annotation( "PMID:16860783") "The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules that contributes to the shaping of the heart.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-09-29T11:34:06Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061343") -AnnotationAssertion(rdfs:label "cell adhesion involved in heart morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of cell adhesion involved in heart morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_heart") Annotation( "PMID:16860783") "Any process that modulates the extent of cell adhesion contributing to the shaping of the heart.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-09-29T11:35:27Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061344") -AnnotationAssertion(rdfs:label "regulation of cell adhesion involved in heart morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (neural precursor cell proliferation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:yaf") "The multiplication or reproduction of neural precursor cells, resulting in the expansion of a cell population. A neural precursor cell is either a nervous system stem cell or a nervous system progenitor cell.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-10-01T11:06:04Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061351") -AnnotationAssertion(rdfs:label "neural precursor cell proliferation") -SubClassOf( ) - -# Class: (cell chemotaxis involved in Malpighian tubule morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_kidney_jan10") "The directed movement of the outgrowing Malpighian tubule guided by specific chemical cues/signals. Movement may be towards a guidance cue (positive chemotaxis) or away from it (negative chemotaxis). Guidance contributes to the final positioning of the tubule.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-10-01T11:57:28Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061352") -AnnotationAssertion(rdfs:label "cell chemotaxis involved in Malpighian tubule morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (optic chiasma development) - -AnnotationAssertion(Annotation( "GOC:dph") "The developmental process pertaining to the progression of the optic chiasm from its initial formation to the mature structure. The process begins when the pathfinding of the axons of the developing optic nerve cause some axons to cross at the midline of the brain and ends when the axons are mature.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-10-13T08:00:29Z") -AnnotationAssertion(Annotation( "GOC:dph") "optic chiasm development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061360") -AnnotationAssertion(rdfs:label "optic chiasma development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (testosterone biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:yaf") "The chemical reactions and pathways resulting in the formation of testosterone, an androgen having 17beta-hydroxy and 3-oxo groups, together with unsaturation at C-4 C-5.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-10-27T02:50:48Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061370") -AnnotationAssertion(rdfs:label "testosterone biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (mammillary axonal complex development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:yaf") Annotation( "PMID:10662642") "The progression of the mammillary axonal complex over time, from its formation to the mature structure. The mammillary axonal complex is formed by the axons from the lateral, medial mammillary and the dorsal premammillary nuclei which share a branching pattern. Every neuron gives off one axonal stem that bifurcates into 2 branches. One of the branches is directed dorsally to the thalamus and another caudally to the midbrain.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-11-09T08:49:59Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061373") -AnnotationAssertion(rdfs:label "mammillary axonal complex development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (mammillothalamic axonal tract development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:yaf") Annotation( "PMID:10662642") "The progression of the mammillothalamic axonal tract, from its formation to the mature structure. The mammillothalamic tract is the collection of axons that connects the two major subdivisions of the diencephalon (hypothalamus and thalamus) and closes the diencephalic circuit.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-11-09T08:54:43Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061374") -AnnotationAssertion(rdfs:label "mammillothalamic axonal tract development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (mammillotectal axonal tract development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:yaf") Annotation( "PMID:10662642") "The progression of the mammillotectal tract over time, from its formation to the mature structure. The mammillotectal tract is the collection of axons that connects the ventral diencephalon to the superior colliculus.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-11-09T09:01:14Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061375") -AnnotationAssertion(rdfs:label "mammillotectal axonal tract development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (mammillotegmental axonal tract development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:yaf") Annotation( "PMID:10662642") "The process in which the mammillotegmental tract progresses over time, from its formation to the mature structure. The mammillotegmental tract is the collection of axons that connects the ventral diencephalon to the tegmentum and pons.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-11-09T09:09:29Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061376") -AnnotationAssertion(rdfs:label "mammillotegmental axonal tract development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (mammary gland lobule development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:yaf") "The progression of the mammary gland lobule over time, from its formation to the mature structure. A mammary gland lobule is a small rounded projection of the mammary gland.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-11-09T09:36:29Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061377") -AnnotationAssertion(rdfs:label "mammary gland lobule development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (corpora quadrigemina development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:yaf") "The progression of the corpora quadrigemina over time, from its formation to the mature structure. The corpora quadrigemina is a part of the midbrain that is made up of the superior and inferior colliculi.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-11-09T09:45:36Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061378") -AnnotationAssertion(rdfs:label "corpora quadrigemina development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (inferior colliculus development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:yaf") "The process whose specific outcome is the progression of the inferior colliculus over time, from its formation to the mature structure. The inferior colliculus (IC) (Latin, lower hill) is the principal midbrain nucleus of the auditory pathway and receives input from several more peripheral brainstem nuclei in the auditory pathway, as well as inputs from the auditory cortex. The inferior colliculus has three subdivisions: the central nucleus (CIC), a dorsal cortex (DCIC) by which it is surrounded, and an external cortex (ICX) which is located laterally.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-11-09T09:49:24Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061379") -AnnotationAssertion(rdfs:label "inferior colliculus development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (superior colliculus development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:yaf") "The process whose specific outcome is the progression of the superior colliculus over time, from its formation to the mature structure. The superior colliculus is also known as the optic tectum or simply tectum and is a paired structure that forms a major component of the vertebrate midbrain.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-11-09T09:51:00Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061380") -AnnotationAssertion(rdfs:label "superior colliculus development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (trabecula morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") "The process of shaping a trabecula in an organ. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-12-02T08:51:45Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061383") -AnnotationAssertion(rdfs:label "trabecula morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (heart trabecula morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") "The process of shaping a trabecula in the heart. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-12-02T08:54:20Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061384") -AnnotationAssertion(rdfs:label "heart trabecula morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (fibroblast proliferation involved in heart morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") "The multiplication or reproduction of fibroblasts, resulting in the expansion of a fibroblast population that contributes to the shaping of the heart.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2011-02-10T01:41:59Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061385") -AnnotationAssertion(rdfs:label "fibroblast proliferation involved in heart morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (bone trabecula morphogenesis) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:vk") "The process of shaping a trabecula in bone. A trabecula is a tissue element in the form of a small beam, strut or rod.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2012-02-07T10:15:36Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061430") -AnnotationAssertion(rdfs:label "bone trabecula morphogenesis") -SubClassOf( ) - -# Class: (renal system vasculature development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_kidney_jan10") Annotation( "PMID:11891195") "The process whose specific outcome is the progression of vasculature of the renal system over time, from its formation to the mature structure.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2012-03-08T12:16:24Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061437") -AnnotationAssertion(rdfs:label "renal system vasculature development") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (renal system vasculature morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_kidney_jan10") Annotation( "PMID:11891195") "The process in which the renal system vasculature is generated and organized. Morphogenesis pertains to the creation of form.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2012-03-08T12:21:56Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061438") -AnnotationAssertion(rdfs:label "renal system vasculature morphogenesis") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (kidney vasculature morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_kidney_jan10") "The process in which the kidney vasculature is generated and organized. Morphogenesis pertains to the creation of form.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2012-03-08T12:30:11Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061439") -AnnotationAssertion(rdfs:label "kidney vasculature morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (kidney vasculature development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_kidney_jan10") Annotation( "PMID:11891195") "The process whose specific outcome is the progression of the vasculature of the kidney over time, from its formation to the mature structure.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2012-03-08T12:39:09Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061440") -AnnotationAssertion(rdfs:label "kidney vasculature development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (renal artery morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") Annotation( "PMID:11891195") "The process in which the anatomical structure of a renal artery is generated and organized. Renal arteries supply the kidneys with blood.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2012-03-08T12:42:09Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061441") -AnnotationAssertion(rdfs:label "renal artery morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (connective tissue development) AnnotationAssertion(Annotation( "GOC:BHF") "The progression of a connective tissue over time, from its formation to the mature structure.") @@ -102943,80 +27065,8 @@ AnnotationAssertion( AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0061448") AnnotationAssertion(rdfs:label "connective tissue development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (olfactory bulb tufted cell development) - -AnnotationAssertion(Annotation( "GOC:dph") "The process whose specific outcome is the progression of an olfactory bulb tufted cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2012-05-15T12:30:21Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061449") -AnnotationAssertion(rdfs:label "olfactory bulb tufted cell development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (trophoblast cell migration) - -AnnotationAssertion(Annotation( "GOC:dph") "Trophoblast cell migration that is accomplished by extension and retraction of a pseudopodium. Trophoblast cells line the outside of the blastocyst.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2012-07-10T08:38:37Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061450") -AnnotationAssertion(rdfs:label "trophoblast cell migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (retrotrapezoid nucleus development) - -AnnotationAssertion(Annotation( "GOC:dph") "The progression of the retrotrapezoid nucleus (RTN) over time from it's initial formation to its mature state. The retrotrapezoid nucleus is a group of neurons in the rostral medulla, which are responsible regulating respiration.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2012-07-19T12:38:30Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061451") -AnnotationAssertion(rdfs:label "retrotrapezoid nucleus development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (retrotrapezoid nucleus neuron differentiation) - -AnnotationAssertion(Annotation( "GOC:dph") "The process in which a relatively unspecialized cell acquires specialized features of a neuron whose cell body resides in the retrotrapezoid nucleus.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2012-07-19T12:43:18Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061452") -AnnotationAssertion(rdfs:label "retrotrapezoid nucleus neuron differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (interstitial cell of Cajal differentiation) - -AnnotationAssertion(Annotation( "GOC:dph") "The process in which a relatively unspecialized cell acquires specialized features of an interstitial cell of Cajal. An interstitial cell of Cajal is an intestinal neuroepithelial cell that serves as a pacemaker to trigger gut contraction.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2012-07-20T08:20:50Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") "ICC differentiation") -AnnotationAssertion( "GO:0061453") -AnnotationAssertion(rdfs:label "interstitial cell of Cajal differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (release of sequestered calcium ion into cytosol by Golgi) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "The directed movement of calcium ions (Ca2+) out of the Golgi apparatus into the cytosol.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2012-07-27T02:29:43Z") -AnnotationAssertion( "Golgi calcium ion export") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061454") -AnnotationAssertion(rdfs:label "release of sequestered calcium ion into cytosol by Golgi") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - # Class: (reproductive system development) AnnotationAssertion(Annotation( "GOC:dph") "The progression of the reproductive system over time from its formation to the mature structure. The reproductive system consists of the organs that function in reproduction.") @@ -103025,221 +27075,8 @@ AnnotationAssertion( AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0061458") AnnotationAssertion(rdfs:label "reproductive system development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (protein localization to lysosome) - -AnnotationAssertion(Annotation( "GOC:dph") "A process in which a protein is transported to, or maintained in, a location within a lysosome.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2012-10-05T10:50:51Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061462") -AnnotationAssertion(rdfs:label "protein localization to lysosome") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of type B pancreatic cell proliferation) - -AnnotationAssertion(Annotation( "GOC:dph") "Any process that modulates the frequency, rate or extent of type B pancreatic cell proliferation.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2012-11-01T13:16:23Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061469") -AnnotationAssertion(rdfs:label "regulation of type B pancreatic cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (hematopoietic stem cell homeostasis) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:21508411") "Any biological process involved in the maintenance of the steady-state number of hematopoietic stem cells within a population of cells.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2012-12-04T09:41:02Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061484") -AnnotationAssertion(rdfs:label "hematopoietic stem cell homeostasis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (protein localization to cilium) - -AnnotationAssertion(Annotation( "GOC:dph") "A process in which a protein is transported to, or maintained in, a location within a cilium.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "dph") -AnnotationAssertion( "2013-03-22T15:41:44Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061512") -AnnotationAssertion(rdfs:label "protein localization to cilium") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) -SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) -SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) -SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) -SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) -SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) -SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) -SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) -SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) -SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) -SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) -SubClassOf( ObjectAllValuesFrom( )) -DisjointClasses( ObjectSomeValuesFrom( )) -DisjointClasses( ObjectSomeValuesFrom( )) -DisjointClasses( ObjectSomeValuesFrom( )) -DisjointClasses( ObjectSomeValuesFrom( )) -DisjointClasses( ObjectSomeValuesFrom( )) -DisjointClasses( ObjectSomeValuesFrom( )) - -# Class: (myeloid cell development) - -AnnotationAssertion(Annotation( "GOC:dph") "The process whose specific outcome is the progression of a myeloid cell over time, from its formation to the mature structure.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2013-04-18T13:03:16Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061515") -AnnotationAssertion(rdfs:label "myeloid cell development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (macrophage homeostasis) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:21727904") "The process of regulating the proliferation and elimination of macrophage cells such that the total number of myeloid cells within a whole or part of an organism is stable over time in the absence of an outside stimulus.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2013-04-18T13:25:33Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061519") -AnnotationAssertion(rdfs:label "macrophage homeostasis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (Langerhans cell differentiation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:22729249") "The process in which a precursor cell type acquires the specialized features of a Langerhans cell.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2013-04-18T13:29:07Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061520") -AnnotationAssertion(rdfs:label "Langerhans cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (hepatic stellate cell differentiation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:9407545") "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a hepatic stellate cell.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2013-04-18T13:36:08Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061521") -AnnotationAssertion(rdfs:label "hepatic stellate cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (cilium disassembly) - -AnnotationAssertion(Annotation( "GOC:cilia") Annotation( "GOC:dph") Annotation( "PMID:17604723") Annotation( "PMID:27350441") "A cellular process that results in the breakdown of a cilium.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2013-04-18T14:59:59Z") -AnnotationAssertion(Annotation( "GOC:dph") "cilium resorption") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061523") -AnnotationAssertion(rdfs:comment "Note that we deem cilium and microtubule-based flagellum to be equivalent.") -AnnotationAssertion(rdfs:label "cilium disassembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (central canal development) - -AnnotationAssertion(Annotation( "GOC:cvs") Annotation( "GOC:dph") Annotation( "PMID:23409159") "The process whose specific outcome is the formation of the central canal of the spinal cord from its formation to the mature structure. The central canal is a spinal cord structure that is part of the ventricular system and is filled with cerebral-spinal fluid and runs the length of the spinal cord.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2013-04-20T08:18:31Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061524") -AnnotationAssertion(rdfs:label "central canal development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (hindgut development) - -AnnotationAssertion(Annotation( "GOC:dph") "The process whose specific outcome is the progression of the hindgut over time, from its formation to the mature structure. The hindgut is part of the alimentary canal that lies posterior to the midgut.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2013-06-14T11:22:21Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061525") -AnnotationAssertion(rdfs:label "hindgut development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (acetylcholine secretion) - -AnnotationAssertion(Annotation( "GOC:dph") "The regulated release of acetylcholine by a cell.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2013-06-21T15:40:39Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061526") -AnnotationAssertion(rdfs:label "acetylcholine secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (dopamine secretion, neurotransmission) - -AnnotationAssertion(Annotation( "GOC:dph") "The regulated release of dopamine by a cell in which the dopamine acts as a neurotransmitter.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2013-06-21T15:43:15Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061527") -AnnotationAssertion(rdfs:label "dopamine secretion, neurotransmission") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (epinephrine secretion, neurotransmission) - -AnnotationAssertion(Annotation( "GOC:dph") "The regulated release of epinephrine by a cell in which the epinephrine acts as a neurotransmitter.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2013-06-21T15:47:22Z") -AnnotationAssertion(Annotation( "GOC:dph") "adrenaline secretion, neurotransmission") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061529") -AnnotationAssertion(rdfs:label "epinephrine secretion, neurotransmission") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (norepinephrine secretion, neurotransmission) - -AnnotationAssertion(Annotation( "GOC:dph") "The regulated release of norepinephrine by a cell, in which the norepinephrine acts as a neurotransmitter.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2013-06-21T16:05:08Z") -AnnotationAssertion(Annotation( "GOC:dph") "noradrenaline secretion, neurotransmission") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061533") -AnnotationAssertion(rdfs:label "norepinephrine secretion, neurotransmission") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (gamma-aminobutyric acid secretion, neurotransmission) - -AnnotationAssertion(Annotation( "GOC:dph") "The regulated release of gamma-aminobutyric acid by a cell, in which the gamma-aminobutyric acid acts as a neurotransmitter.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2013-06-21T16:10:50Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061534") -AnnotationAssertion(rdfs:label "gamma-aminobutyric acid secretion, neurotransmission") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (glutamate secretion, neurotransmission) AnnotationAssertion(Annotation( "GOC:dph") "The controlled release of glutamate by a cell, in which the glutamate acts as a neurotransmitter.") @@ -103248,356 +27085,10 @@ AnnotationAssertion( AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0061535") AnnotationAssertion(rdfs:label "glutamate secretion, neurotransmission") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (ganglion development) - -AnnotationAssertion(Annotation( "GOC:dph") "The process whose specific outcome is the progression of a ganglion over time, from its formation to the mature structure.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2013-07-10T08:36:12Z") -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:rl") "gangliogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") "ganglia development") -AnnotationAssertion( "GO:0061548") -AnnotationAssertion(rdfs:label "ganglion development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (sympathetic ganglion development) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:rl") "The process whose specific outcome is the progression of a sympathetic ganglion over time, from its formation to the mature structure.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2013-07-10T08:38:01Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") "sympathetic ganglia development") -AnnotationAssertion( "GO:0061549") -AnnotationAssertion(rdfs:label "sympathetic ganglion development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cranial ganglion development) - -AnnotationAssertion(Annotation( "GOC:dph") "The process whose specific outcome is the progression of a cranial ganglion over time, from its formation to the mature structure.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2013-07-10T08:40:14Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") "cranial ganglia development") -AnnotationAssertion( "GO:0061550") -AnnotationAssertion(rdfs:label "cranial ganglion development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (trigeminal ganglion development) - -AnnotationAssertion(Annotation( "GOC:dph") "The process whose specific outcome is the progression of a trigeminal ganglion over time, from its formation to the mature structure.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2013-07-10T08:42:19Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") "trigeminal ganglia development") -AnnotationAssertion( "GO:0061551") -AnnotationAssertion(rdfs:label "trigeminal ganglion development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (ganglion morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") "The process in which the anatomical structures of ganglion are generated and organized.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2013-07-10T08:44:57Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") "ganglia morphogenesis") -AnnotationAssertion( "GO:0061552") -AnnotationAssertion(rdfs:label "ganglion morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (ganglion maturation) - -AnnotationAssertion(Annotation( "GOC:dph") "A developmental process, independent of morphogenetic (shape) change, that is required for ganglion to attain its fully functional state.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2013-07-10T08:45:59Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") "ganglia maturation") -AnnotationAssertion( "GO:0061553") -AnnotationAssertion(rdfs:label "ganglion maturation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (ganglion formation) - -AnnotationAssertion(Annotation( "GOC:dph") "The process that gives rise to ganglion. This process pertains to the initial formation of a structure from unspecified parts.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2013-07-10T08:51:50Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") "ganglia formation") -AnnotationAssertion( "GO:0061554") -AnnotationAssertion(rdfs:label "ganglion formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (trigeminal ganglion morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") "The process in which the anatomical structure of a trigeminal ganglion is generated and organized.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2013-07-10T08:57:12Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") "trigeminal ganglia morphogenesis") -AnnotationAssertion( "GO:0061556") -AnnotationAssertion(rdfs:label "trigeminal ganglion morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (trigeminal ganglion maturation) - -AnnotationAssertion(Annotation( "GOC:dph") "A developmental process, independent of morphogenetic (shape) change, that is required for a trigeminal ganglion to attain its fully functional state.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2013-07-10T08:58:24Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") "trigeminal ganglia maturation") -AnnotationAssertion( "GO:0061557") -AnnotationAssertion(rdfs:label "trigeminal ganglion maturation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cranial ganglion maturation) - -AnnotationAssertion(Annotation( "GOC:dph") "A developmental process, independent of morphogenetic (shape) change, that is required for a cranial ganglion to attain its fully functional state.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2013-07-10T08:59:52Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") "cranial ganglia maturation") -AnnotationAssertion( "GO:0061558") -AnnotationAssertion(rdfs:label "cranial ganglion maturation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cranial ganglion morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") "The process in which the anatomical structure of a cranial ganglion is generated and organized.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2013-07-10T09:02:15Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") "cranial ganglia morphogenesis") -AnnotationAssertion( "GO:0061559") -AnnotationAssertion(rdfs:label "cranial ganglion morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cranial ganglion formation) - -AnnotationAssertion(Annotation( "GOC:dph") "The process that gives rise to a cranial ganglion. This process pertains to the initial formation of a structure from unspecified parts.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2013-07-10T09:07:27Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") "cranial ganglia formation") -AnnotationAssertion( "GO:0061560") -AnnotationAssertion(rdfs:label "cranial ganglion formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (trigeminal ganglion formation) - -AnnotationAssertion(Annotation( "GOC:dph") "The process that gives rise to the trigeminal ganglion. This process pertains to the initial formation of a structure from unspecified parts.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2013-07-10T09:08:13Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") "trigeminal ganglia formation") -AnnotationAssertion( "GO:0061561") -AnnotationAssertion(rdfs:label "trigeminal ganglion formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (axon development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:pg") Annotation( "GOC:pr") "The progression of an axon over time. Covers axonogenesis (de novo generation of an axon) and axon regeneration (regrowth), as well as processes pertaining to the progression of the axon over time (fasciculation and defasciculation).") -AnnotationAssertion( "dph") -AnnotationAssertion( "2013-07-18T14:43:01Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061564") -AnnotationAssertion(rdfs:label "axon development") -SubClassOf( ) - -# Class: (actin filament bundle organization) - -AnnotationAssertion(Annotation( "GOC:dph") "A process that results in the assembly, arrangement of constituent parts, or disassembly of an actin filament bundle.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2013-08-02T11:24:11Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") "actin filament cable organization") -AnnotationAssertion( "GO:0061572") -AnnotationAssertion(rdfs:label "actin filament bundle organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (colon epithelial cell migration) - -AnnotationAssertion(Annotation( "GOC:dph") "The orderly movement of a colonic epithelial cell from one site to another, often during the development of a multicellular organism.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2013-12-23T07:26:54Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061580") -AnnotationAssertion(rdfs:label "colon epithelial cell migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (corneal epithelial cell migration) - -AnnotationAssertion(Annotation( "GOC:dph") "The orderly movement of a corneal epithelial cell from one site to another, often during the development of a multicellular organism.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2013-12-23T07:28:29Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061581") -AnnotationAssertion(rdfs:label "corneal epithelial cell migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (intestinal epithelial cell migration) - -AnnotationAssertion(Annotation( "GOC:dph") "The orderly movement of an intestinal epithelial cell from one site to another, often during the development of a multicellular organism.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2013-12-23T07:30:55Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061582") -AnnotationAssertion(rdfs:label "intestinal epithelial cell migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (pharyngeal arch artery morphogenesis) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "PMID:20122914") "The process in which the anatomical structures of a pharyngeal arch artery is generated and organized. The pharyngeal arch arteries are a series of six paired embryological vascular structures, the development of which give rise to several major arteries, such as the stapedial artery, the middle meningeal artery, the internal carotid artery and the pulmonary artery.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2014-05-09T15:34:06Z") -AnnotationAssertion(Annotation( "GOC:dph") "aortic arch artery morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061626") -AnnotationAssertion(rdfs:label "pharyngeal arch artery morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (RNA polymerase II-specific DNA-binding transcription factor binding) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:vw") "Binding to a sequence-specific DNA binding RNA polymerase II transcription factor, any of the factors that interact selectively and non-covalently with a specific DNA sequence in order to modulate transcription.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/19354"^^xsd:anyURI) -AnnotationAssertion( "dph") -AnnotationAssertion( "2014-05-15T09:12:24Z") -AnnotationAssertion( "GO:0001085") -AnnotationAssertion( "GO:0001102") -AnnotationAssertion( "GO:0001103") -AnnotationAssertion( "RNA polymerase II sequence-specific DNA binding transcription factor binding") -AnnotationAssertion( "RNA polymerase II sequence-specific DNA-binding transcription factor binding") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "RNA polymerase II activating transcription factor binding") -AnnotationAssertion( "RNA polymerase II repressing transcription factor binding") -AnnotationAssertion( "RNA polymerase II transcription factor binding") -AnnotationAssertion( "GO:0061629") -AnnotationAssertion(rdfs:label "RNA polymerase II-specific DNA-binding transcription factor binding") -SubClassOf( ) - -# Class: (seminal vesicle morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") "The process in which the anatomical structures of a seminal vesicle are generated and organized.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2015-03-04T13:33:49Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061682") -AnnotationAssertion(rdfs:label "seminal vesicle morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (branching involved in seminal vesicle morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:16916376") "The process in which the branching structure of the seminal vesicle is generated and organized. A branch is a division or offshoot from a main stem.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2015-03-04T13:39:47Z") -AnnotationAssertion(Annotation( "GOC:dph") "gonecyst branching morphogenesis") -AnnotationAssertion(Annotation( "GOC:dph") "seminal gland branching morphogenesis") -AnnotationAssertion(Annotation( "GOC:dph") "seminal vesicle branching") -AnnotationAssertion(Annotation( "GOC:dph") "seminal vesicle branching morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061683") -AnnotationAssertion(rdfs:label "branching involved in seminal vesicle morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (detoxification of inorganic compound) - -AnnotationAssertion(Annotation( "GOC:vw") "Any process that reduces or removes the toxicity of inorganic compounds. These include transport of such compounds away from sensitive areas and to compartments or complexes whose purpose is sequestration of inorganic compounds.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2015-03-09T09:16:23Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061687") -AnnotationAssertion(rdfs:label "detoxification of inorganic compound") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (transferase complex, transferring phosphorus-containing groups) - -AnnotationAssertion(Annotation( "GOC:bhm") Annotation( "GOC:dph") "A transferase complex capable of catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor).") -AnnotationAssertion( "dph") -AnnotationAssertion( "2015-05-06T11:22:38Z") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0061695") -AnnotationAssertion(rdfs:label "transferase complex, transferring phosphorus-containing groups") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (anterior neural tube closure) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:hal") Annotation( "PMID:17286298") "The step in the formation of the neural tube, where the paired anterior neural folds are brought together and fuse at the dorsal midline.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2015-06-23T10:13:41Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061713") -AnnotationAssertion(rdfs:label "anterior neural tube closure") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cytosolic lipolysis) - -AnnotationAssertion(Annotation( "GOC:autophagy") "The chemical reactions and pathways resulting in the breakdown of lipid droplets and hydrolysis of stored triglycerides occurring through the orchestrated activation of cytosolic lipases.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2015-07-08T13:42:15Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061725") -AnnotationAssertion(rdfs:label "cytosolic lipolysis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (secretory granule maturation) - -AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:bf") Annotation( "GOC:dph") Annotation( "PMID:16618809") "Steps required to transform an immature secretory vesicle into a mature secretory vesicle. Typically proceeds through homotypic membrane fusion and membrane remodeling.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2016-09-09T13:24:34Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061792") -AnnotationAssertion(rdfs:label "secretory granule maturation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - # Class: (antimicrobial humoral immune response mediated by antimicrobial peptide) AnnotationAssertion(Annotation( "PMID:15761415") Annotation( "PMID:24287494") "An immune response against microbes mediated by anti-microbial peptides in body fluid.") @@ -103608,268 +27099,6 @@ AnnotationAssertion( "antimicrobial humoral immune response mediated by antimicrobial peptide") SubClassOf( ) -# Class: (regulation of neuroblast migration) - -AnnotationAssertion(Annotation( "PMID:23149556") "Any process that modulates the frequency, rate or extent of neuroblast migration.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2017-03-08T18:17:07Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061853") -AnnotationAssertion(rdfs:label "regulation of neuroblast migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of neuroblast migration) - -AnnotationAssertion(Annotation( "PMID:23149556") "Any process that activates or increases the frequency, rate or extent of neuroblast migration.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2017-03-08T18:22:30Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061854") -AnnotationAssertion(rdfs:label "positive regulation of neuroblast migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of neuroblast migration) - -AnnotationAssertion(Annotation( "PMID:23149556") "Any process that stops, prevents, or reduces the frequency, rate or extent of neuroblast migration.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2017-03-08T18:26:21Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061855") -AnnotationAssertion(rdfs:label "negative regulation of neuroblast migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (Golgi calcium ion transmembrane transport) - -AnnotationAssertion(Annotation( "PMID:21811607") "A process in which a calcium ion is transported from one side of a Golgi membrane to the other by means of some agent such as a transporter or pore.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2017-03-14T16:08:23Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061856") -AnnotationAssertion(rdfs:label "Golgi calcium ion transmembrane transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (hepatic stellate cell migration) - -AnnotationAssertion(Annotation( "PMID:24204762") "The orderly movement of a hepatic stellate cell from one site to another.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2017-05-01T13:01:40Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061868") -AnnotationAssertion(rdfs:label "hepatic stellate cell migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of hepatic stellate cell migration) - -AnnotationAssertion(Annotation( "PMID:24204762") "Any process that modulates the frequency, rate or extent of hepatic stellate cell migration.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2017-05-01T13:04:20Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061869") -AnnotationAssertion(rdfs:label "regulation of hepatic stellate cell migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of hepatic stellate cell migration) - -AnnotationAssertion(Annotation( "PMID:24204762") "Any process that increases the frequency, rate or extent of hepatic stellate cell migration.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2017-05-01T13:17:23Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061870") -AnnotationAssertion(rdfs:label "positive regulation of hepatic stellate cell migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of hepatic stellate cell migration) - -AnnotationAssertion(Annotation( "PMID:24204762") "Any process that stops, prevents or reduces the frequency, rate or extent of hepatic stellate cell migration.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2017-05-01T13:20:51Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061871") -AnnotationAssertion(rdfs:label "negative regulation of hepatic stellate cell migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of astrocyte activation) - -AnnotationAssertion(Annotation( "GOC:aruk") Annotation( "GOC:bc") Annotation( "PMID:20005821") "Any process that modulates the frequency, rate or extent of astrocyte activation.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2017-06-01T22:26:29Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061888") -AnnotationAssertion(rdfs:label "regulation of astrocyte activation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (negative regulation of astrocyte activation) - -AnnotationAssertion(Annotation( "GOC:aruk") Annotation( "GOC:bc") Annotation( "PMID:20005821") "Any process that decreases the frequency, rate or extent of astrocyte activation.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2017-06-01T22:29:43Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061889") -AnnotationAssertion(rdfs:label "negative regulation of astrocyte activation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of astrocyte activation) - -AnnotationAssertion(Annotation( "GOC:aruk") Annotation( "GOC:bc") Annotation( "PMID:20005821") "Any process that increases the frequency, rate or extent of astrocyte activation.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2017-06-01T22:31:50Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061890") -AnnotationAssertion(rdfs:label "positive regulation of astrocyte activation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (glial cell activation) - -AnnotationAssertion(Annotation( "GOC:aruk") Annotation( "GOC:bc") Annotation( "PMID:18723082") "A change in morphology and behavior of a glial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2017-06-13T13:06:23Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061900") -AnnotationAssertion(rdfs:label "glial cell activation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (regulation of adenine biosynthetic process) - -AnnotationAssertion(Annotation( "PMID:19933844") "Any process that modulates the frequency, rate or extent of an adenine biosynthetic process.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2017-09-05T14:58:46Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061934") -AnnotationAssertion(rdfs:label "regulation of adenine biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (protein localization to somatodendritic compartment) - -AnnotationAssertion(Annotation( "PMID:18341993") "A process in which a protein is transported to or maintained in a location within the somatodendritic compartment.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2017-09-08T13:22:26Z") -AnnotationAssertion( "somatodendritic protein localization") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061938") -AnnotationAssertion(rdfs:label "protein localization to somatodendritic compartment") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (establishment of protein localization to plasma membrane) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:vw") "The directed movement of a protein to a specific location in a plasma membrane.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2017-10-26T12:55:15Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061951") -AnnotationAssertion(rdfs:label "establishment of protein localization to plasma membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (replacement bone morphogenesis) - -AnnotationAssertion(Annotation( "PMID:29852585") "The process in which bones are generated and organized as a result of the conversion of another structural tissue into bone.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2018-02-12T18:10:59Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061971") -AnnotationAssertion(rdfs:label "replacement bone morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (dermal bone morphogenesis) - -AnnotationAssertion(Annotation( "PMID:12588850") Annotation( "PMID:15003632") "The process in which bone which forms superficially in the organism are generated and organized.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2018-02-12T18:16:21Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061972") -AnnotationAssertion(rdfs:label "dermal bone morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (membrane bone morphogenesis) - -AnnotationAssertion(Annotation( "PMID:14579374") "The process in which bone which forms deep in the organism are generated and organized.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2018-02-12T18:21:09Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061973") -AnnotationAssertion(rdfs:label "membrane bone morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (perichondral bone morphogenesis) - -AnnotationAssertion(Annotation( "PMID:21901110") "The process in which bones are generated and organized as a result of the conversion of initial connective tissue surrounding cartilage into bone.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2018-02-12T18:26:10Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061974") -AnnotationAssertion(rdfs:label "perichondral bone morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (meiosis II cell cycle process) - -AnnotationAssertion(Annotation( "PMID:29385397") "A process that coontributes to the second meiotic division. The second meiotic division separates chromatids resulting in a haploid number of chromosomes.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2018-02-14T22:37:44Z") -AnnotationAssertion(Annotation( "PMID:29385397") "second meiotic division") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0061983") -AnnotationAssertion(rdfs:label "meiosis II cell cycle process") -SubClassOf( ) - -# Class: (secondary palate development) - -AnnotationAssertion(Annotation( "PMID:28784960") "The biological process whose specific outcome is the progression of the secondary palate from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The secondary palate is the part of the palate formed from the fusion of the two palatine shelves, extensions of the maxillary prominences.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2018-02-26T22:55:20Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0062009") -AnnotationAssertion(rdfs:label "secondary palate development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (primitive palate development) - -AnnotationAssertion(Annotation( "GOC:dph") "The biological process whose specific outcome is the progression of the primitive palate from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2018-02-26T23:00:48Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0062010") -AnnotationAssertion(rdfs:label "primitive palate development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of small molecule metabolic process) - -AnnotationAssertion(Annotation( "GOC:vw") "Any process that modulates the rate, frequency or extent of a small molecule metabolic process.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2018-03-19T14:11:54Z") -AnnotationAssertion( "regulation of small molecule metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0062012") -AnnotationAssertion(rdfs:label "regulation of small molecule metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of small molecule metabolic process) - -AnnotationAssertion(Annotation( "GOC:vw") "Any process that activates or increases the frequency, rate or extent of a small molecule metabolic process.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2018-03-19T14:25:10Z") -AnnotationAssertion( "positive regulation of small molecule metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0062013") -AnnotationAssertion(rdfs:label "positive regulation of small molecule metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of small molecule metabolic process) - -AnnotationAssertion(Annotation( "GOC:vw") "Any process that stops, prevents or reduces the frequency, rate or extent of a small molecule metabolic process.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2018-03-19T14:27:23Z") -AnnotationAssertion( "negative regulation of small molecule metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0062014") -AnnotationAssertion(rdfs:label "negative regulation of small molecule metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (collagen-containing extracellular matrix) AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:rph") Annotation( "PMID:21123617") "An extracellular matrix consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that provides not only essential physical scaffolding for the cellular constituents but can also initiate crucial biochemical and biomechanical cues required for tissue morphogenesis, differentiation and homeostasis. The components are secreted by cells in the vicinity and form a sheet underlying or overlying cells such as endothelial and epithelial cells.") @@ -103882,136 +27111,6 @@ SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectAllValuesFrom( )) -# Class: (positive regulation of mitotic sister chromatid segregation) - -AnnotationAssertion(Annotation( "PMID:12773390") "Any process that starts or increases the frequency, rate or extent of sister chromatid segregation during mitosis.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2018-04-23T14:32:23Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0062033") -AnnotationAssertion(rdfs:label "positive regulation of mitotic sister chromatid segregation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (stomach development) - -AnnotationAssertion(Annotation( "PMID:11967278") "The process whose specific outcome is the progression of the stomach over time, from its formation to the mature structure. The stomach is an expanded region of the vertebrate alimentary tract that serves as a food storage compartment and digestive organ.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2018-11-20T18:15:45Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0062094") -AnnotationAssertion(rdfs:label "stomach development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (detection of stimulus involved in sensory perception of pain) - -AnnotationAssertion(Annotation( "PMID:19837031") "The series of events involved in the perception of pain in which a stimulus is received and converted into a molecular signal.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2019-09-13T13:48:47Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0062149") -AnnotationAssertion(rdfs:label "detection of stimulus involved in sensory perception of pain") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (lutein metabolic process) - -AnnotationAssertion(Annotation( "PMID:24397433") "The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform lutein.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2019-11-18T15:56:36Z") -AnnotationAssertion( "lutein metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0062170") -AnnotationAssertion(rdfs:label "lutein metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (lutein biosynthetic process) - -AnnotationAssertion(Annotation( "PMID:24397433") "The chemical reactions and pathways resulting in the formation of lutein.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2019-11-18T16:01:00Z") -AnnotationAssertion( "lutein anabolism") -AnnotationAssertion( "lutein biosynthesis") -AnnotationAssertion( "lutein formation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0062171") -AnnotationAssertion(rdfs:label "lutein biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (lutein catabolic process) - -AnnotationAssertion(Annotation( "PMID:24397433") "The chemical reactions and pathways resulting in the breakdown of lutein.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2019-11-18T16:06:07Z") -AnnotationAssertion( "lutein breakdown") -AnnotationAssertion( "lutein catabolism") -AnnotationAssertion( "lutein degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0062172") -AnnotationAssertion(rdfs:label "lutein catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of somatic muscle development) - -AnnotationAssertion(Annotation( "PMID:16643882") Annotation( "PMID:25758712") "Any process that regulates the rate, frequency or extent of somatic muscle development.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2020-03-13T18:58:37Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0062223") -AnnotationAssertion(rdfs:label "regulation of somatic muscle development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of somatic muscle development) - -AnnotationAssertion(Annotation( "PMID:16643882") Annotation( "PMID:25758712") "Any process that increases the rate, frequency or extent of somatic muscle development.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2020-03-13T19:03:38Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0062224") -AnnotationAssertion(rdfs:label "positive regulation of somatic muscle development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of somatic muscle development) - -AnnotationAssertion(Annotation( "PMID:16643882") Annotation( "PMID:25758712") "Any process that decreases the rate, frequency or extent of somatic muscle development.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2020-03-13T19:06:27Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0062225") -AnnotationAssertion(rdfs:label "negative regulation of somatic muscle development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (ionocyte differentiation) - -AnnotationAssertion(Annotation( "PMID:17555741") "The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of an ionocyte. Ionocytes are specialized epithelial cells that contribute to osmotic homeostasis.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2020-04-20T12:30:35Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0062236") -AnnotationAssertion(rdfs:label "ionocyte differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (protein localization to postsynapse) - -AnnotationAssertion(Annotation( "PMID:31189538") "Any process in which a protein is transported to, and/or maintained at the postsynapse, the part of a synapse that is part of the post-synaptic cell.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2020-04-20T13:58:43Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0062237") -AnnotationAssertion(rdfs:label "protein localization to postsynapse") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (intracellular protein transmembrane transport) - -AnnotationAssertion(Annotation( "GOC:isa_complete") "The directed movement of proteins in a cell, from one side of a membrane to another by means of some agent such as a transporter or pore.") -AnnotationAssertion( "intracellular membrane translocation of a protein") -AnnotationAssertion( "intracellular protein membrane transport") -AnnotationAssertion( "intracellular protein transport across a membrane") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0065002") -AnnotationAssertion(rdfs:comment "Note that this term is not intended for use in annotating lateral movement within membranes.") -AnnotationAssertion(rdfs:label "intracellular protein transmembrane transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - # Class: (protein-containing complex assembly) AnnotationAssertion(Annotation( "GOC:jl") "The aggregation, arrangement and bonding together of a set of macromolecules to form a protein-containing complex.") @@ -104037,20 +27136,8 @@ AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "protein-containing complex assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (protein-DNA complex assembly) - -AnnotationAssertion(Annotation( "GOC:jl") "The aggregation, arrangement and bonding together of proteins and DNA molecules to form a protein-DNA complex.") -AnnotationAssertion(Annotation( "GOC:mah") "DNA-protein complex assembly") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0065004") -AnnotationAssertion(rdfs:label "protein-DNA complex assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - # Class: (biological regulation) AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:isa_complete") Annotation( "GOC:mah") Annotation( "GOC:pr") Annotation( "GOC:vw") "Any process that modulates a measurable attribute of any biological process, quality or function.") @@ -104073,126 +27160,14 @@ AnnotationAssertion( "regulation of biological quality") SubClassOf( ) -# Class: (regulation of molecular function) - -AnnotationAssertion(Annotation( "GOC:isa_complete") "Any process that modulates the frequency, rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding.") -AnnotationAssertion( "regulation of a molecular function") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0065009") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "regulation of molecular function") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (extracellular membrane-bounded organelle) - -AnnotationAssertion(Annotation( "GOC:isa_complete") "Organized structure of distinctive morphology and function, bounded by a lipid bilayer membrane and occurring outside the cell.") -AnnotationAssertion( "extracellular membrane-enclosed organelle") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0065010") -AnnotationAssertion(rdfs:label "extracellular membrane-bounded organelle") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (intracellular organelle lumen) - -AnnotationAssertion(Annotation( "GOC:mah") "An organelle lumen that is part of an intracellular organelle.") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0070013") -AnnotationAssertion(rdfs:label "intracellular organelle lumen") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (neuron cellular homeostasis) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mah") "The cellular homeostatic process that preserves a neuron in a stable, differentiated functional and structural state.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/24218"^^xsd:anyURI) -AnnotationAssertion( "neuron maintenance") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0070050") -AnnotationAssertion(rdfs:label "neuron cellular homeostasis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (fibrinogen binding) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mah") Annotation( "GOC:vk") "Binding to fibrinogen, a highly soluble hexameric glycoprotein complex that is found in blood plasma and is converted to fibrin by thrombin in the coagulation cascade.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0070051") -AnnotationAssertion(rdfs:label "fibrinogen binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (extracellular exosome) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mah") Annotation( "GOC:vesicles") Annotation( "PMID:15908444") Annotation( "PMID:17641064") Annotation( "PMID:19442504") Annotation( "PMID:19498381") Annotation( "PMID:22418571") Annotation( "PMID:24009894") "A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.") -AnnotationAssertion(Annotation( "GOC:pr") "exosome") -AnnotationAssertion(Annotation( "GOC:vesicles") "extracellular vesicular exosome") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0070062") -AnnotationAssertion(rdfs:label "extracellular exosome") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (glucagon secretion) AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:rl") "The regulated release of glucagon from secretory granules in the A (alpha) cells of the pancreas (islets of Langerhans).") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0070091") AnnotationAssertion(rdfs:label "glucagon secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (regulation of glucagon secretion) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the regulated release of glucagon.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0070092") -AnnotationAssertion(rdfs:label "regulation of glucagon secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (negative regulation of glucagon secretion) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of glucagon.") -AnnotationAssertion( "down regulation of glucagon secretion") -AnnotationAssertion( "down-regulation of glucagon secretion") -AnnotationAssertion( "downregulation of glucagon secretion") -AnnotationAssertion( "inhibition of glucagon secretion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0070093") -AnnotationAssertion(rdfs:label "negative regulation of glucagon secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of glucagon secretion) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of the regulated release of glucagon.") -AnnotationAssertion( "up regulation of glucagon secretion") -AnnotationAssertion( "up-regulation of glucagon secretion") -AnnotationAssertion( "upregulation of glucagon secretion") -AnnotationAssertion( "activation of glucagon secretion") -AnnotationAssertion( "stimulation of glucagon secretion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0070094") -AnnotationAssertion(rdfs:label "positive regulation of glucagon secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (Kupffer's vesicle development) - -AnnotationAssertion(Annotation( "GOC:dgh") "The progression of the Kupffer's vesicle over time from its initial formation until its mature state. The Kupffer's vesicle is a small but distinctive epithelial sac containing fluid, located midventrally posterior to the yolk cell or its extension, and transiently present during most of the segmentation period.") -AnnotationAssertion(Annotation( "GOC:dgh") "KV development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0070121") -AnnotationAssertion(rdfs:label "Kupffer's vesicle development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - # Class: (tight junction) AnnotationAssertion(Annotation( "ISBN:0815332181") "A cell-cell junction that seals cells together in an epithelium in a way that prevents even small molecules from leaking from one side of the sheet to the other.") @@ -104213,267 +27188,12 @@ AnnotationAssertion( "anchoring junction") SubClassOf( ) -# Class: (regulation of biomineral tissue development) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of biomineral tissue development, the formation of hard tissues that consist mainly of inorganic compounds.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0070167") -AnnotationAssertion(rdfs:label "regulation of biomineral tissue development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (negative regulation of biomineral tissue development) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of biomineral tissue development, the formation of hard tissues that consist mainly of inorganic compounds.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0070168") -AnnotationAssertion(rdfs:label "negative regulation of biomineral tissue development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of biomineral tissue development) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of biomineral tissue development, the formation of hard tissues that consist mainly of inorganic compounds.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0070169") -AnnotationAssertion(rdfs:label "positive regulation of biomineral tissue development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of tooth mineralization) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of tooth mineralization, the deposition of calcium salts in tooth structures.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0070170") -AnnotationAssertion(rdfs:label "regulation of tooth mineralization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of tooth mineralization) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of tooth mineralization, the deposition of calcium salts in tooth structures.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0070171") -AnnotationAssertion(rdfs:label "negative regulation of tooth mineralization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of tooth mineralization) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of tooth mineralization, the deposition of calcium salts in tooth structures.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0070172") -AnnotationAssertion(rdfs:label "positive regulation of tooth mineralization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (chromosome organization involved in meiotic cell cycle) - -AnnotationAssertion(Annotation( "GOC:mah") "A process of chromosome organization that is involved in a meiotic cell cycle.") -AnnotationAssertion(Annotation( "GOC:mah") "chromosome organisation involved in meiosis") -AnnotationAssertion(Annotation( "GOC:mah") "meiotic chromosome organization") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0070192") -AnnotationAssertion(rdfs:label "chromosome organization involved in meiotic cell cycle") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (establishment of protein localization to chromosome) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mah") "The directed movement of a protein to a specific location on a chromosome.") -AnnotationAssertion(Annotation( "GOC:mah") "establishment of protein localisation to chromosome") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0070199") -AnnotationAssertion(rdfs:label "establishment of protein localization to chromosome") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of establishment of protein localization) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location.") -AnnotationAssertion(Annotation( "GOC:mah") "regulation of establishment of protein localisation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0070201") -AnnotationAssertion(rdfs:label "regulation of establishment of protein localization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of establishment of protein localization to chromosome) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location on a chromosome.") -AnnotationAssertion(Annotation( "GOC:mah") "regulation of establishment of protein localisation to chromosome") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0070202") -AnnotationAssertion(rdfs:label "regulation of establishment of protein localization to chromosome") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (lymphocyte apoptotic process) - -AnnotationAssertion(Annotation( "CL:0000542") Annotation( "GOC:add") Annotation( "GOC:mtg_apoptosis") Annotation( "ISBN:0781765196") "Any apoptotic process in a lymphocyte, a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin.") -AnnotationAssertion( "lymphocyte apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0070227") -AnnotationAssertion(rdfs:comment "Note that a lymphocyte is a cell of the B cell, T cell, or natural killer cell lineage (CL:0000542).") -AnnotationAssertion(rdfs:label "lymphocyte apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of lymphocyte apoptotic process) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:mtg_apoptosis") Annotation( "ISBN:0781765196") "Any process that modulates the occurrence or rate of lymphocyte death by apoptotic process.") -AnnotationAssertion( "regulation of lymphocyte apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0070228") -AnnotationAssertion(rdfs:comment "Note that a lymphocyte is a cell of the B cell, T cell, or natural killer cell lineage (CL:0000542).") -AnnotationAssertion(rdfs:label "regulation of lymphocyte apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of lymphocyte apoptotic process) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:mtg_apoptosis") Annotation( "ISBN:0781765196") "Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte death by apoptotic process.") -AnnotationAssertion(Annotation( "GOC:add") "down regulation of lymphocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:add") "down-regulation of lymphocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:add") "downregulation of lymphocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:add") "inhibition of lymphocyte apoptosis") -AnnotationAssertion( "negative regulation of lymphocyte apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0070229") -AnnotationAssertion(rdfs:comment "Note that a lymphocyte is a cell of the B cell, T cell, or natural killer cell lineage (CL:0000542).") -AnnotationAssertion(rdfs:label "negative regulation of lymphocyte apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of lymphocyte apoptotic process) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:mtg_apoptosis") Annotation( "ISBN:0781765196") "Any process that activates or increases the frequency, rate or extent of lymphocyte death by apoptotic process.") -AnnotationAssertion(Annotation( "GOC:add") "up regulation of lymphocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:add") "up-regulation of lymphocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:add") "upregulation of lymphocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:add") "activation of lymphocyte apoptosis") -AnnotationAssertion( "positive regulation of lymphocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:add") "stimulation of lymphocyte apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0070230") -AnnotationAssertion(rdfs:comment "Note that a lymphocyte is a cell of the B cell, T cell, or natural killer cell lineage (CL:0000542).") -AnnotationAssertion(rdfs:label "positive regulation of lymphocyte apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (T cell apoptotic process) - -AnnotationAssertion(Annotation( "CL:0000084") Annotation( "GOC:add") Annotation( "GOC:mtg_apoptosis") Annotation( "ISBN:0781765196") "Any apoptotic process in a T cell, a type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex.") -AnnotationAssertion(Annotation( "GOC:add") "T lymphocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:add") "T-cell apoptosis") -AnnotationAssertion(Annotation( "GOC:add") "T-lymphocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:add") "programmed cell death of T cells by apoptosis") -AnnotationAssertion( "T cell apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0070231") -AnnotationAssertion(rdfs:label "T cell apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of T cell apoptotic process) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:mtg_apoptosis") Annotation( "ISBN:0781765196") "Any process that modulates the occurrence or rate of T cell death by apoptotic process.") -AnnotationAssertion(Annotation( "GOC:add") "regulation of T lymphocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:add") "regulation of T-cell apoptosis") -AnnotationAssertion(Annotation( "GOC:add") "regulation of T-lymphocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:add") "regulation of programmed cell death of T cells by apoptosis") -AnnotationAssertion( "regulation of T cell apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0070232") -AnnotationAssertion(rdfs:label "regulation of T cell apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of T cell apoptotic process) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:mtg_apoptosis") Annotation( "ISBN:0781765196") "Any process that stops, prevents, or reduces the frequency, rate or extent of T cell death by apoptotic process.") -AnnotationAssertion(Annotation( "GOC:add") "down regulation of T cell apoptosis") -AnnotationAssertion(Annotation( "GOC:add") "down-regulation of T cell apoptosis") -AnnotationAssertion(Annotation( "GOC:add") "downregulation of T cell apoptosis") -AnnotationAssertion(Annotation( "GOC:add") "negative regulation of T lymphocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:add") "negative regulation of T-cell apoptosis") -AnnotationAssertion(Annotation( "GOC:add") "negative regulation of T-lymphocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:add") "negative regulation of programmed cell death of T cells by apoptosis") -AnnotationAssertion(Annotation( "GOC:add") "inhibition of T cell apoptosis") -AnnotationAssertion( "negative regulation of T cell apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0070233") -AnnotationAssertion(rdfs:label "negative regulation of T cell apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of T cell apoptotic process) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:mtg_apoptosis") Annotation( "ISBN:0781765196") "Any process that activates or increases the frequency, rate or extent of T cell death by apoptotic process.") -AnnotationAssertion(Annotation( "GOC:add") "positive regulation of T lymphocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:add") "positive regulation of T-cell apoptosis") -AnnotationAssertion(Annotation( "GOC:add") "positive regulation of T-lymphocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:add") "positive regulation of programmed cell death of T cells by apoptosis") -AnnotationAssertion(Annotation( "GOC:add") "up regulation of T cell apoptosis") -AnnotationAssertion(Annotation( "GOC:add") "up-regulation of T cell apoptosis") -AnnotationAssertion(Annotation( "GOC:add") "upregulation of T cell apoptosis") -AnnotationAssertion(Annotation( "GOC:add") "activation of T cell apoptosis") -AnnotationAssertion( "positive regulation of T cell apoptosis") -AnnotationAssertion(Annotation( "GOC:add") "stimulation of T cell apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0070234") -AnnotationAssertion(rdfs:label "positive regulation of T cell apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (thymocyte apoptotic process) - -AnnotationAssertion(Annotation( "CL:0000893") Annotation( "GOC:add") Annotation( "GOC:mtg_apoptosis") Annotation( "ISBN:0781765196") "Any apoptotic process in a thymocyte, an immature T cell located in the thymus.") -AnnotationAssertion( "thymocyte apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:add") "immature T cell apoptosis") -AnnotationAssertion( "GO:0070242") -AnnotationAssertion(rdfs:comment "Note that a thymocyte is an immature T cell located in the thymus (CL:0000893).") -AnnotationAssertion(rdfs:label "thymocyte apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of thymocyte apoptotic process) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:mtg_apoptosis") Annotation( "ISBN:0781765196") "Any process that modulates the occurrence or rate of thymocyte death by apoptotic process.") -AnnotationAssertion( "regulation of thymocyte apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:add") "regulation of immature T cell apoptosis") -AnnotationAssertion( "GO:0070243") -AnnotationAssertion(rdfs:comment "Note that a thymocyte is an immature T cell located in the thymus (CL:0000893).") -AnnotationAssertion(rdfs:label "regulation of thymocyte apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of thymocyte apoptotic process) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:mtg_apoptosis") Annotation( "ISBN:0781765196") "Any process that stops, prevents, or reduces the frequency, rate or extent of thymocyte death by apoptotic process.") -AnnotationAssertion(Annotation( "GOC:add") "down regulation of thymocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:add") "down-regulation of thymocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:add") "downregulation of thymocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:add") "inhibition of thymocyte apoptosis") -AnnotationAssertion( "negative regulation of thymocyte apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:add") "negative regulation of immature T cell apoptosis") -AnnotationAssertion( "GO:0070244") -AnnotationAssertion(rdfs:comment "Note that a thymocyte is an immature T cell located in the thymus (CL:0000893).") -AnnotationAssertion(rdfs:label "negative regulation of thymocyte apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of thymocyte apoptotic process) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:mtg_apoptosis") Annotation( "ISBN:0781765196") "Any process that activates or increases the frequency, rate or extent of thymocyte death by apoptotic process.") -AnnotationAssertion(Annotation( "GOC:add") "up regulation of thymocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:add") "up-regulation of thymocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:add") "upregulation of thymocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:add") "activation of thymocyte apoptosis") -AnnotationAssertion( "positive regulation of thymocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:add") "stimulation of thymocyte apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:add") "positive regulation of immature T cell apoptosis") -AnnotationAssertion( "GO:0070245") -AnnotationAssertion(rdfs:comment "Note that a thymocyte is an immature T cell located in the thymus (CL:0000893).") -AnnotationAssertion(rdfs:label "positive regulation of thymocyte apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (somatostatin secretion) AnnotationAssertion(Annotation( "GOC:mah") "The regulated release of somatostatin from secretory granules in the D cells of the pancreas.") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0070253") AnnotationAssertion(rdfs:label "somatostatin secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) # Class: (mucus secretion) @@ -104483,46 +27203,9 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:0070254") AnnotationAssertion(rdfs:label "mucus secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) -# Class: (regulation of mucus secretion) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that modulates the frequency, rate or extent of the regulated release of mucus from a cell or a tissue.") -AnnotationAssertion(Annotation( "GOC:add") "regulation of mucus production") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0070255") -AnnotationAssertion(rdfs:label "regulation of mucus secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of mucus secretion) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of mucus from a cell or a tissue.") -AnnotationAssertion(Annotation( "GOC:add") "negative regulation of mucus production") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0070256") -AnnotationAssertion(rdfs:label "negative regulation of mucus secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of mucus secretion) - -AnnotationAssertion(Annotation( "GOC:add") "Any process that activates or increases the frequency, rate or extent of the regulated release of mucus from a cell or a tissue.") -AnnotationAssertion(Annotation( "GOC:add") "positive regulation of mucus production") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0070257") -AnnotationAssertion(rdfs:label "positive regulation of mucus secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - # Class: (extracellular matrix constituent secretion) AnnotationAssertion(Annotation( "GOC:mah") "The controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell.") @@ -104534,16 +27217,6 @@ AnnotationAssertion(rdfs:label "extr SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (pigment cell development) - -AnnotationAssertion(Annotation( "GOC:cvs") "The process whose specific outcome is the progression of a pigment cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a pigment cell fate.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0070285") -AnnotationAssertion(rdfs:label "pigment cell development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (renal absorption) AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mah") Annotation( "GOC:yaf") "A renal system process in which water, ions, glucose and proteins are taken up from the collecting ducts, glomerulus and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures (e.g. protein absorption is observed in nephrocytes in Drosophila, see PMID:23264686).") @@ -104565,299 +27238,6 @@ AnnotationAssertion(rdfs:label "rena SubClassOf( ) SubClassOf( ) -# Class: (lens fiber cell differentiation) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "PMID:7693735") "The process in which a relatively unspecialized cell acquires specialized features of a lens fiber cell, any of the elongated, tightly packed cells that make up the bulk of the mature lens in the camera-type eye. The cytoplasm of a lens fiber cell is devoid of most intracellular organelles including the cell nucleus, and contains primarily crystallins, a group of water-soluble proteins expressed in vary large quantities.") -AnnotationAssertion(Annotation( "GOC:mah") "lens fibre cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0070306") -AnnotationAssertion(rdfs:label "lens fiber cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (lens fiber cell development) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "PMID:7693735") "The process whose specific outcome is the progression of a lens fiber cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a lens fiber cell fate. A lens fiber cell is any of the elongated, tightly packed cells that make up the bulk of the mature lens in a camera-type eye.") -AnnotationAssertion(Annotation( "GOC:mah") "lens fibre cell development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0070307") -AnnotationAssertion(rdfs:label "lens fiber cell development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (fat cell proliferation) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:sl") "The multiplication or reproduction of fat cells by cell division, resulting in the expansion of their population. A fat cell is an animal connective tissue cell specialized for the synthesis and storage of fat.") -AnnotationAssertion(Annotation( "GOC:sl") "adipocyte proliferation") -AnnotationAssertion(Annotation( "GOC:sl") "adipose cell proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0070341") -AnnotationAssertion(rdfs:label "fat cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (brown fat cell proliferation) - -AnnotationAssertion(Annotation( "CL:0000449") Annotation( "GOC:mah") Annotation( "GOC:sl") "The multiplication or reproduction of brown fat cells by cell division, resulting in the expansion of their population. A brown fat cell is a fat cell found the thermogenic form of adipose tissue found in newborns of many species.") -AnnotationAssertion( ) -AnnotationAssertion(Annotation( "GOC:sl") "brown adipocyte proliferation") -AnnotationAssertion(Annotation( "GOC:sl") "brown adipose cell proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0070342") -AnnotationAssertion(rdfs:label "brown fat cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) -DisjointClasses( ObjectSomeValuesFrom( )) - -# Class: (white fat cell proliferation) - -AnnotationAssertion(Annotation( "CL:0000448") Annotation( "GOC:mah") Annotation( "GOC:sl") "The multiplication or reproduction of white fat cells by cell division, resulting in the expansion of their population.") -AnnotationAssertion(Annotation( "GOC:sl") "white adipocyte proliferation") -AnnotationAssertion(Annotation( "GOC:sl") "white adipose cell proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0070343") -AnnotationAssertion(rdfs:label "white fat cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of fat cell proliferation) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:sl") "Any process that modulates the frequency, rate or extent of fat cell proliferation.") -AnnotationAssertion(Annotation( "GOC:sl") "regulation of adipocyte proliferation") -AnnotationAssertion(Annotation( "GOC:sl") "regulation of adipose cell proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0070344") -AnnotationAssertion(rdfs:label "regulation of fat cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of fat cell proliferation) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:sl") "Any process that stops or decreases the rate or extent of fat cell proliferation.") -AnnotationAssertion(Annotation( "GOC:mah") "down regulation of fat cell proliferation") -AnnotationAssertion(Annotation( "GOC:mah") "down-regulation of fat cell proliferation") -AnnotationAssertion(Annotation( "GOC:mah") "downregulation of fat cell proliferation") -AnnotationAssertion(Annotation( "GOC:sl") "negative regulation of adipocyte proliferation") -AnnotationAssertion(Annotation( "GOC:sl") "negative regulation of adipose cell proliferation") -AnnotationAssertion(Annotation( "GOC:mah") "inhibition of fat cell proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0070345") -AnnotationAssertion(rdfs:label "negative regulation of fat cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of fat cell proliferation) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:sl") "Any process that activates or increases the rate or extent of fat cell proliferation.") -AnnotationAssertion(Annotation( "GOC:sl") "positive regulation of adipocyte proliferation") -AnnotationAssertion(Annotation( "GOC:sl") "positive regulation of adipose cell proliferation") -AnnotationAssertion(Annotation( "GOC:mah") "up regulation of fat cell proliferation") -AnnotationAssertion(Annotation( "GOC:mah") "up-regulation of fat cell proliferation") -AnnotationAssertion(Annotation( "GOC:mah") "upregulation of fat cell proliferation") -AnnotationAssertion(Annotation( "GOC:mah") "activation of fat cell proliferation") -AnnotationAssertion(Annotation( "GOC:mah") "stimulation of fat cell proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0070346") -AnnotationAssertion(rdfs:label "positive regulation of fat cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of brown fat cell proliferation) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:sl") "Any process that modulates the frequency, rate or extent of brown fat cell proliferation.") -AnnotationAssertion(Annotation( "GOC:sl") "regulation of brown adipocyte proliferation") -AnnotationAssertion(Annotation( "GOC:sl") "regulation of brown adipose cell proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0070347") -AnnotationAssertion(rdfs:label "regulation of brown fat cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of brown fat cell proliferation) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:sl") "Any process that stops or decreases the rate or extent of brown fat cell proliferation.") -AnnotationAssertion(Annotation( "GOC:mah") "down regulation of brown fat cell proliferation") -AnnotationAssertion(Annotation( "GOC:mah") "down-regulation of brown fat cell proliferation") -AnnotationAssertion(Annotation( "GOC:mah") "downregulation of brown fat cell proliferation") -AnnotationAssertion(Annotation( "GOC:sl") "negative regulation of brown adipocyte proliferation") -AnnotationAssertion(Annotation( "GOC:sl") "negative regulation of brown adipose cell proliferation") -AnnotationAssertion(Annotation( "GOC:mah") "inhibition of brown fat cell proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0070348") -AnnotationAssertion(rdfs:label "negative regulation of brown fat cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of brown fat cell proliferation) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:sl") "Any process that activates or increases the rate or extent of brown fat cell proliferation.") -AnnotationAssertion(Annotation( "GOC:sl") "positive regulation of brown adipocyte proliferation") -AnnotationAssertion(Annotation( "GOC:sl") "positive regulation of brown adipose cell proliferation") -AnnotationAssertion(Annotation( "GOC:mah") "up regulation of brown fat cell proliferation") -AnnotationAssertion(Annotation( "GOC:mah") "up-regulation of brown fat cell proliferation") -AnnotationAssertion(Annotation( "GOC:mah") "upregulation of brown fat cell proliferation") -AnnotationAssertion(Annotation( "GOC:mah") "activation of brown fat cell proliferation") -AnnotationAssertion(Annotation( "GOC:mah") "stimulation of brown fat cell proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0070349") -AnnotationAssertion(rdfs:label "positive regulation of brown fat cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of white fat cell proliferation) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:sl") "Any process that modulates the frequency, rate or extent of white fat cell proliferation.") -AnnotationAssertion(Annotation( "GOC:sl") "regulation of white adipocyte proliferation") -AnnotationAssertion(Annotation( "GOC:sl") "regulation of white adipose cell proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0070350") -AnnotationAssertion(rdfs:label "regulation of white fat cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of white fat cell proliferation) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:sl") "Any process that stops or decreases the rate or extent of white fat cell proliferation.") -AnnotationAssertion(Annotation( "GOC:mah") "down regulation of white fat cell proliferation") -AnnotationAssertion(Annotation( "GOC:mah") "down-regulation of white fat cell proliferation") -AnnotationAssertion(Annotation( "GOC:mah") "downregulation of white fat cell proliferation") -AnnotationAssertion(Annotation( "GOC:sl") "negative regulation of white adipocyte proliferation") -AnnotationAssertion(Annotation( "GOC:sl") "negative regulation of white adipose cell proliferation") -AnnotationAssertion(Annotation( "GOC:mah") "inhibition of white fat cell proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0070351") -AnnotationAssertion(rdfs:label "negative regulation of white fat cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of white fat cell proliferation) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:sl") "Any process that activates or increases the rate or extent of white fat cell proliferation.") -AnnotationAssertion(Annotation( "GOC:sl") "positive regulation of white adipocyte proliferation") -AnnotationAssertion(Annotation( "GOC:sl") "positive regulation of white adipose cell proliferation") -AnnotationAssertion(Annotation( "GOC:mah") "up regulation of white fat cell proliferation") -AnnotationAssertion(Annotation( "GOC:mah") "up-regulation of white fat cell proliferation") -AnnotationAssertion(Annotation( "GOC:mah") "upregulation of white fat cell proliferation") -AnnotationAssertion(Annotation( "GOC:mah") "activation of white fat cell proliferation") -AnnotationAssertion(Annotation( "GOC:mah") "stimulation of white fat cell proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0070352") -AnnotationAssertion(rdfs:label "positive regulation of white fat cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (hepatocyte differentiation) - -AnnotationAssertion(Annotation( "CL:0000182") Annotation( "PMID:7588884") "The process in which a relatively unspecialized cell acquires the specialized features of a hepatocyte. A hepatocyte is specialized epithelial cell that is organized into interconnected plates called lobules, and is the main structural component of the liver.") -AnnotationAssertion(Annotation( "GOC:mah") "liver cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0070365") -AnnotationAssertion(rdfs:label "hepatocyte differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (regulation of hepatocyte differentiation) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:sl") "Any process that modulates the frequency, rate or extent of hepatocyte differentiation.") -AnnotationAssertion(Annotation( "GOC:sl") "regulation of liver cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0070366") -AnnotationAssertion(rdfs:label "regulation of hepatocyte differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of hepatocyte differentiation) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:sl") "Any process that stops or decreases the rate or extent of hepatocyte differentiation.") -AnnotationAssertion(Annotation( "GOC:mah") "down regulation of hepatocyte differentiation") -AnnotationAssertion(Annotation( "GOC:mah") "down-regulation of hepatocyte differentiation") -AnnotationAssertion(Annotation( "GOC:mah") "downregulation of hepatocyte differentiation") -AnnotationAssertion(Annotation( "GOC:sl") "negative regulation of liver cell differentiation") -AnnotationAssertion(Annotation( "GOC:mah") "inhibition of hepatocyte differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0070367") -AnnotationAssertion(rdfs:label "negative regulation of hepatocyte differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (positive regulation of hepatocyte differentiation) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:sl") "Any process that activates or increases the rate or extent of hepatocyte differentiation.") -AnnotationAssertion(Annotation( "GOC:sl") "positive regulation of liver cell differentiation") -AnnotationAssertion(Annotation( "GOC:mah") "up regulation of hepatocyte differentiation") -AnnotationAssertion(Annotation( "GOC:mah") "up-regulation of hepatocyte differentiation") -AnnotationAssertion(Annotation( "GOC:mah") "upregulation of hepatocyte differentiation") -AnnotationAssertion(Annotation( "GOC:mah") "activation of hepatocyte differentiation") -AnnotationAssertion(Annotation( "GOC:mah") "stimulation of hepatocyte differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0070368") -AnnotationAssertion(rdfs:label "positive regulation of hepatocyte differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (exocytic vesicle) - -AnnotationAssertion(Annotation( "GOC:kad") Annotation( "GOC:mah") "A transport vesicle that mediates transport from an intracellular compartment to the plasma membrane, and fuses with the plasma membrane to release various cargo molecules, such as proteins or hormones, by exocytosis.") -AnnotationAssertion( "exocytic constitutive secretory pathway transport vesicle") -AnnotationAssertion(Annotation( "GOC:kad") "exocytotic vesicle") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0070382") -AnnotationAssertion(rdfs:label "exocytic vesicle") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (Harderian gland development) - -AnnotationAssertion(Annotation( "GOC:hjd") Annotation( "PMID:16856596") Annotation( "PMID:7559104") "The process whose specific outcome is the progression of the Harderian gland over time, from its formation to the mature structure. The Harderian gland is an anterior orbital structure usually associated with the nictitating membrane, and produces and secretes a variety of substances to the eye, depending upon the species.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0070384") -AnnotationAssertion(rdfs:comment "Note that the Harderian gland is found in all terrestrial vertebrate groups, including amphibia, reptiles, birds, and mammals. However, it appears to be absent in certain mammals such as bats, cows, horses, and higher primates. Though largely absent in the adult human, it is present in the fetal and neonatal stages.") -AnnotationAssertion(rdfs:label "Harderian gland development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (ammonium ion binding) - -AnnotationAssertion(Annotation( "CHEBI:28938") Annotation( "GOC:ecd") "Binding to ammonium ions (NH4+).") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "ammonium binding") -AnnotationAssertion( "GO:0070405") -AnnotationAssertion(rdfs:label "ammonium ion binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (oligodendrocyte progenitor proliferation) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:sl") Annotation( "PMID:15504915") "The multiplication or reproduction of oligodendrocyte progenitor cells by cell division, resulting in the expansion of their population. Oligodendrocyte progenitors give rise to oligodendrocytes, which form the insulating myelin sheath of axons in the central nervous system.") -AnnotationAssertion(Annotation( "GOC:mah") "oligodendrocyte precursor proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0070444") -AnnotationAssertion(rdfs:label "oligodendrocyte progenitor proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (regulation of oligodendrocyte progenitor proliferation) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:sl") "Any process that modulates the frequency, rate or extent of oligodendrocyte progenitor proliferation.") -AnnotationAssertion(Annotation( "GOC:mah") "regulation of oligodendrocyte precursor proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0070445") -AnnotationAssertion(rdfs:label "regulation of oligodendrocyte progenitor proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of oligodendrocyte progenitor proliferation) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:sl") "Any process that stops or decreases the rate or extent of oligodendrocyte progenitor proliferation.") -AnnotationAssertion(Annotation( "GOC:mah") "negative regulation of oligodendrocyte precursor proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0070446") -AnnotationAssertion(rdfs:label "negative regulation of oligodendrocyte progenitor proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (positive regulation of oligodendrocyte progenitor proliferation) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:sl") "Any process that activates or increases the rate or extent of oligodendrocyte progenitor proliferation.") -AnnotationAssertion(Annotation( "GOC:mah") "positive regulation of oligodendrocyte precursor proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0070447") -AnnotationAssertion(rdfs:label "positive regulation of oligodendrocyte progenitor proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - # Class: (cell hair) AnnotationAssertion(Annotation( "PMID:11526084") "A long, thin cell projection that contains F-actin and tubulin, with microtubules centrally located and F-actin peripherally located.") @@ -104869,15 +27249,6 @@ AnnotationAssertion( "cell hair") SubClassOf( ) -# Class: (prolactin secretion) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "ISBN:0198506732") "The regulated release of prolactin, a peptide hormone that stimulates lactation, from secretory granules in the anterior pituitary.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0070459") -AnnotationAssertion(rdfs:label "prolactin secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - # Class: (response to oxygen levels) AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of oxygen.") @@ -104896,83 +27267,6 @@ AnnotationAssertion(rdfs:label "dete SubClassOf( ) SubClassOf( ) -# Class: (regulation of microtubule cytoskeleton organization) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins.") -AnnotationAssertion(Annotation( "GOC:mah") "regulation of microtubule cytoskeleton organisation") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "regulation of microtubule dynamics") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0070507") -AnnotationAssertion(rdfs:label "regulation of microtubule cytoskeleton organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (response to fatty acid) - -AnnotationAssertion(Annotation( "GOC:lp") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fatty acid stimulus.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0070542") -AnnotationAssertion(rdfs:label "response to fatty acid") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (protein secretion by platelet) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mah") "The regulated release of proteins by a platelet or group of platelets.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2009-04-09T02:38:05Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0070560") -AnnotationAssertion(rdfs:label "protein secretion by platelet") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (calcium ion transmembrane transport) - -AnnotationAssertion(Annotation( "GOC:mah") "A process in which a calcium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2009-04-28T10:44:09Z") -AnnotationAssertion( "calcium ion membrane transport") -AnnotationAssertion(Annotation( "GOC:mah") "transmembrane calcium transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0070588") -AnnotationAssertion(rdfs:comment "Note that this term is not intended for use in annotating lateral movement within membranes.") -AnnotationAssertion(rdfs:label "calcium ion transmembrane transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of protein processing) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of protein processing, a protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2009-04-29T02:49:14Z") -AnnotationAssertion( "GO:0010953") -AnnotationAssertion( "regulation of protein maturation by peptide bond cleavage") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0070613") -AnnotationAssertion(rdfs:label "regulation of protein processing") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (transepithelial transport) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:yaf") Annotation( "ISBN:0716731363") "The directed movement of a substance from one side of an epithelium to the other.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2009-05-06T03:31:02Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0070633") -AnnotationAssertion(rdfs:label "transepithelial transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (transepithelial ammonium transport) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:yaf") "The directed movement of ammonium ions from one side of an epithelium to the other.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2009-05-06T03:34:43Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0070634") -AnnotationAssertion(rdfs:label "transepithelial ammonium transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (leukocyte proliferation) AnnotationAssertion(Annotation( "GOC:add") "The expansion of a leukocyte population by cell division.") @@ -104981,54 +27275,10 @@ AnnotationAssertion( AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0070661") AnnotationAssertion(rdfs:label "leukocyte proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectAllValuesFrom( )) -# Class: (regulation of leukocyte proliferation) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of leukocyte proliferation.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2009-05-28T05:30:39Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0070663") -AnnotationAssertion(rdfs:label "regulation of leukocyte proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (negative regulation of leukocyte proliferation) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of leukocyte proliferation.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2009-05-28T05:34:50Z") -AnnotationAssertion(Annotation( "GOC:mah") "down regulation of leukocyte proliferation") -AnnotationAssertion(Annotation( "GOC:mah") "down-regulation of leukocyte proliferation") -AnnotationAssertion(Annotation( "GOC:mah") "downregulation of leukocyte proliferation") -AnnotationAssertion(Annotation( "GOC:mah") "inhibition of leukocyte proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0070664") -AnnotationAssertion(rdfs:label "negative regulation of leukocyte proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (positive regulation of leukocyte proliferation) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of leukocyte proliferation.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2009-05-28T05:36:46Z") -AnnotationAssertion(Annotation( "GOC:mah") "up regulation of leukocyte proliferation") -AnnotationAssertion(Annotation( "GOC:mah") "up-regulation of leukocyte proliferation") -AnnotationAssertion(Annotation( "GOC:mah") "upregulation of leukocyte proliferation") -AnnotationAssertion(Annotation( "GOC:mah") "activation of leukocyte proliferation") -AnnotationAssertion(Annotation( "GOC:mah") "stimulation of leukocyte proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0070665") -AnnotationAssertion(rdfs:label "positive regulation of leukocyte proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - # Class: (cellular macromolecule localization) AnnotationAssertion(Annotation( "GOC:mah") "Any process in which a macromolecule is transported to, and/or maintained in, a specific location at the level of a cell. Localization at the cellular level encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell.") @@ -105041,144 +27291,6 @@ AnnotationAssertion(rdfs:label "cell SubClassOf( ) SubClassOf( ) -# Class: (bicellular tight junction assembly) - -AnnotationAssertion(Annotation( "GOC:mah") "The aggregation, arrangement and bonding together of a set of components to form a tight junction, an occluding cell-cell junction that is composed of a branching network of sealing strands that completely encircles the apical end of each cell in an epithelial sheet.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2009-07-23T04:32:38Z") -AnnotationAssertion(Annotation( "GOC:mah") "tight junction formation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0070830") -AnnotationAssertion(rdfs:label "bicellular tight junction assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (basement membrane assembly) - -AnnotationAssertion(Annotation( "GOC:mah") "The aggregation, arrangement and bonding together of a set of components to form a basement membrane, a part of the extracellular region that consists of a thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2009-07-23T05:01:51Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0070831") -AnnotationAssertion(rdfs:comment "Note that this term has no relationship to 'membrane assembly ; GO:0071709' because the basement membrane is not a lipid bilayer.") -AnnotationAssertion(rdfs:label "basement membrane assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (growth factor receptor binding) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:vw") "Binding to a growth factor receptor.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2009-08-07T11:23:02Z") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0070851") -AnnotationAssertion(rdfs:label "growth factor receptor binding") -SubClassOf( ) - -# Class: (regulation of bile acid biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2009-08-14T03:09:02Z") -AnnotationAssertion(Annotation( "GOC:mah") "regulation of bile acid anabolism") -AnnotationAssertion(Annotation( "GOC:mah") "regulation of bile acid biosynthesis") -AnnotationAssertion(Annotation( "GOC:mah") "regulation of bile acid formation") -AnnotationAssertion(Annotation( "GOC:mah") "regulation of bile acid synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0070857") -AnnotationAssertion(rdfs:label "regulation of bile acid biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of bile acid biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2009-08-14T03:16:40Z") -AnnotationAssertion(Annotation( "GOC:mah") "down regulation of bile acid biosynthetic process") -AnnotationAssertion(Annotation( "GOC:mah") "down-regulation of bile acid biosynthetic process") -AnnotationAssertion(Annotation( "GOC:mah") "downregulation of bile acid biosynthetic process") -AnnotationAssertion(Annotation( "GOC:mah") "negative regulation of bile acid anabolism") -AnnotationAssertion(Annotation( "GOC:mah") "negative regulation of bile acid biosynthesis") -AnnotationAssertion(Annotation( "GOC:mah") "negative regulation of bile acid formation") -AnnotationAssertion(Annotation( "GOC:mah") "negative regulation of bile acid synthesis") -AnnotationAssertion(Annotation( "GOC:mah") "inhibition of bile acid biosynthetic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0070858") -AnnotationAssertion(rdfs:label "negative regulation of bile acid biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of bile acid biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2009-08-14T03:22:58Z") -AnnotationAssertion(Annotation( "GOC:mah") "positive regulation of bile acid anabolism") -AnnotationAssertion(Annotation( "GOC:mah") "positive regulation of bile acid biosynthesis") -AnnotationAssertion(Annotation( "GOC:mah") "positive regulation of bile acid formation") -AnnotationAssertion(Annotation( "GOC:mah") "positive regulation of bile acid synthesis") -AnnotationAssertion(Annotation( "GOC:mah") "up regulation of bile acid biosynthetic process") -AnnotationAssertion(Annotation( "GOC:mah") "up-regulation of bile acid biosynthetic process") -AnnotationAssertion(Annotation( "GOC:mah") "upregulation of bile acid biosynthetic process") -AnnotationAssertion(Annotation( "GOC:mah") "activation of bile acid biosynthetic process") -AnnotationAssertion(Annotation( "GOC:mah") "stimulation of bile acid biosynthetic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0070859") -AnnotationAssertion(rdfs:label "positive regulation of bile acid biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of glycogen metabolic process) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving glycogen.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2009-08-20T02:44:53Z") -AnnotationAssertion(Annotation( "GOC:mah") "regulation of glycogen metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0070873") -AnnotationAssertion(rdfs:label "regulation of glycogen metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of glycogen metabolic process) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving glycogen.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2009-08-20T02:50:41Z") -AnnotationAssertion(Annotation( "GOC:mah") "negative regulation of glycogen metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0070874") -AnnotationAssertion(rdfs:label "negative regulation of glycogen metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of glycogen metabolic process) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving glycogen.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2009-08-20T02:53:55Z") -AnnotationAssertion(Annotation( "GOC:mah") "positive regulation of glycogen metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0070875") -AnnotationAssertion(rdfs:label "positive regulation of glycogen metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - # Class: (cellular response to chemical stimulus) AnnotationAssertion(Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus.") @@ -105192,590 +27304,6 @@ AnnotationAssertion(rdfs:label "cell SubClassOf( ) SubClassOf( ) -# Class: (organelle assembly) - -AnnotationAssertion(Annotation( "GOC:mah") "The aggregation, arrangement and bonding together of a set of components to form an organelle. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2009-09-15T03:00:51Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0070925") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "organelle assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (bone maturation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mah") "A developmental process, independent of morphogenetic (shape) change, that is required for bone to attain its fully functional state.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2009-10-05T04:35:31Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0070977") -AnnotationAssertion(rdfs:label "bone maturation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (regulation of phospholipid biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phospholipids.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2009-11-04T03:05:11Z") -AnnotationAssertion(Annotation( "GOC:mah") "regulation of phospholipid anabolism") -AnnotationAssertion(Annotation( "GOC:mah") "regulation of phospholipid biosynthesis") -AnnotationAssertion(Annotation( "GOC:mah") "regulation of phospholipid formation") -AnnotationAssertion(Annotation( "GOC:mah") "regulation of phospholipid synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0071071") -AnnotationAssertion(rdfs:label "regulation of phospholipid biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of phospholipid biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phospholipids.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2009-11-04T03:14:08Z") -AnnotationAssertion(Annotation( "GOC:mah") "down regulation of phospholipid biosynthetic process") -AnnotationAssertion(Annotation( "GOC:ma") "down-regulation of phospholipid biosynthetic process") -AnnotationAssertion(Annotation( "GOC:mah") "downregulation of phospholipid biosynthetic process") -AnnotationAssertion(Annotation( "GOC:mah") "negative regulation of phospholipid anabolism") -AnnotationAssertion(Annotation( "GOC:mah") "negative regulation of phospholipid biosynthesis") -AnnotationAssertion(Annotation( "GOC:mah") "negative regulation of phospholipid formation") -AnnotationAssertion(Annotation( "GOC:mah") "negative regulation of phospholipid synthesis") -AnnotationAssertion(Annotation( "GOC:mah") "inhibition of phospholipid biosynthetic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0071072") -AnnotationAssertion(rdfs:label "negative regulation of phospholipid biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of phospholipid biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phospholipids.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2009-11-04T03:18:51Z") -AnnotationAssertion(Annotation( "GOC:mah") "positive regulation of phospholipid anabolism") -AnnotationAssertion(Annotation( "GOC:mah") "positive regulation of phospholipid biosynthesis") -AnnotationAssertion(Annotation( "GOC:mah") "positive regulation of phospholipid formation") -AnnotationAssertion(Annotation( "GOC:mah") "positive regulation of phospholipid synthesis") -AnnotationAssertion(Annotation( "GOC:mah") "up regulation of phospholipid biosynthetic process") -AnnotationAssertion(Annotation( "GOC:mah") "up-regulation of phospholipid biosynthetic process") -AnnotationAssertion(Annotation( "GOC:mah") "upregulation of phospholipid biosynthetic process") -AnnotationAssertion(Annotation( "GOC:mah") "activation of phospholipid biosynthetic process") -AnnotationAssertion(Annotation( "GOC:mah") "stimulation of phospholipid biosynthetic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0071073") -AnnotationAssertion(rdfs:label "positive regulation of phospholipid biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (superior temporal gyrus development) - -AnnotationAssertion(Annotation( "FMA:61905") Annotation( "GOC:BHF") Annotation( "GOC:mah") Annotation( "PMID:11484000") "The process whose specific outcome is the progression of the superior temporal gyrus over time, from its formation to the mature structure. The superior temporal gyrus is a portion of the cerebral cortex that extends from the lateral sulcus to the superior temporal sulcus.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2009-11-12T02:19:23Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0071109") -AnnotationAssertion(rdfs:label "superior temporal gyrus development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (protein localization to chromatin) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process in which a protein is transported to, or maintained at, a part of a chromosome that is organized into chromatin.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2009-11-20T11:51:20Z") -AnnotationAssertion(Annotation( "GOC:mah") "protein localisation to chromatin") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0071168") -AnnotationAssertion(rdfs:label "protein localization to chromatin") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (establishment of protein localization to chromatin) - -AnnotationAssertion(Annotation( "GOC:mah") "The directed movement of a protein to a part of a chromosome that is organized into chromatin.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2009-11-20T11:52:43Z") -AnnotationAssertion(Annotation( "GOC:mah") "establishment of protein localisation to chromatin") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0071169") -AnnotationAssertion(rdfs:label "establishment of protein localization to chromatin") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (cellular response to abiotic stimulus) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abiotic (non-living) stimulus.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2009-12-03T01:02:11Z") -AnnotationAssertion(Annotation( "GOC:mah") "cellular response to abiotic stress") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0071214") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.") -AnnotationAssertion(rdfs:label "cellular response to abiotic stimulus") -SubClassOf( ) -SubClassOf( ) - -# Class: (cellular response to amino acid stimulus) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2009-12-03T02:08:11Z") -AnnotationAssertion(Annotation( "GOC:mah") "cellular response to amino acid") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0071230") -AnnotationAssertion(rdfs:label "cellular response to amino acid stimulus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cellular response to inorganic substance) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inorganic substance stimulus.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2009-12-03T02:35:49Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0071241") -AnnotationAssertion(rdfs:label "cellular response to inorganic substance") -SubClassOf( ) -SubClassOf( ) - -# Class: (cellular response to ammonium ion) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000071") Annotation( "PMID:23509267") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ammonium stimulus.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2009-12-03T02:39:40Z") -AnnotationAssertion( "GO:1903718") -AnnotationAssertion( "cellular response to ammonia") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0071242") -AnnotationAssertion(rdfs:label "cellular response to ammonium ion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cellular response to carbon dioxide) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbon dioxide (CO2) stimulus.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2009-12-03T02:41:21Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0071244") -AnnotationAssertion(rdfs:label "cellular response to carbon dioxide") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (cellular response to metal ion) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metal ion stimulus.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2009-12-03T02:46:31Z") -AnnotationAssertion(Annotation( "GOC:mah") "cellular response to metal") -AnnotationAssertion(Annotation( "GOC:mah") "cellular response to heavy metal") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0071248") -AnnotationAssertion(rdfs:label "cellular response to metal ion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (cellular response to calcium ion) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2009-12-10T03:55:01Z") -AnnotationAssertion(Annotation( "GOC:mah") "cellular response to Ca2+ ion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0071277") -AnnotationAssertion(rdfs:label "cellular response to calcium ion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (cellular response to iron ion) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron ion stimulus.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2009-12-10T03:57:22Z") -AnnotationAssertion(Annotation( "GOC:mah") "cellular response to iron") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0071281") -AnnotationAssertion(rdfs:label "cellular response to iron ion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cellular response to organic substance) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic substance stimulus.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2009-12-10T04:46:04Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0071310") -AnnotationAssertion(rdfs:label "cellular response to organic substance") -SubClassOf( ) -SubClassOf( ) - -# Class: (cellular response to acetate) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetate stimulus.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2009-12-10T04:48:16Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0071311") -AnnotationAssertion(rdfs:label "cellular response to acetate") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (cellular response to alkaloid) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkaloid stimulus. Alkaloids are a large group of nitrogenous substances found in naturally in plants, many of which have extracts that are pharmacologically active.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2009-12-10T04:50:58Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0071312") -AnnotationAssertion(rdfs:label "cellular response to alkaloid") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cellular response to ATP) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ATP (adenosine 5'-triphosphate) stimulus.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2009-12-10T05:09:47Z") -AnnotationAssertion(Annotation( "GOC:mah") "cellular response to adenosine 5'-triphosphate") -AnnotationAssertion(Annotation( "GOC:mah") "cellular response to adenosine triphosphate") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0071318") -AnnotationAssertion(rdfs:label "cellular response to ATP") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cellular response to carbohydrate stimulus) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbohydrate stimulus.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2009-12-10T05:13:33Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0071322") -AnnotationAssertion(rdfs:label "cellular response to carbohydrate stimulus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (cellular response to chitin) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chitin stimulus.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2009-12-10T05:25:54Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0071323") -AnnotationAssertion(rdfs:label "cellular response to chitin") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cellular response to monosaccharide stimulus) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monosaccharide stimulus.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2009-12-10T05:27:18Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0071326") -AnnotationAssertion(rdfs:label "cellular response to monosaccharide stimulus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cellular response to hexose stimulus) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hexose stimulus.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2009-12-10T05:37:00Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0071331") -AnnotationAssertion(rdfs:label "cellular response to hexose stimulus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cellular response to glucose stimulus) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucose stimulus.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2009-12-10T05:38:03Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0071333") -AnnotationAssertion(rdfs:label "cellular response to glucose stimulus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (cellular response to cytokine stimulus) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokine stimulus.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2009-12-11T02:41:12Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0071345") -AnnotationAssertion(rdfs:label "cellular response to cytokine stimulus") -SubClassOf( ) -SubClassOf( ) - -# Class: (cellular response to peptide hormone stimulus) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide hormone stimulus. A peptide hormone is any of a class of peptides that are secreted into the blood stream and have endocrine functions in living animals.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2009-12-11T03:24:18Z") -AnnotationAssertion(Annotation( "GOC:mah") "cellular response to polypeptide hormone stimulus") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0071375") -AnnotationAssertion(rdfs:label "cellular response to peptide hormone stimulus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cellular response to glucagon stimulus) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucagon stimulus.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2009-12-11T03:25:07Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0071377") -AnnotationAssertion(rdfs:label "cellular response to glucagon stimulus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cellular response to steroid hormone stimulus) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a steroid hormone stimulus.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2009-12-11T03:49:02Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0071383") -AnnotationAssertion(rdfs:label "cellular response to steroid hormone stimulus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cellular response to corticosteroid stimulus) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticosteroid hormone stimulus. A corticosteroid is a steroid hormone that is produced in the adrenal cortex. Corticosteroids are involved in a wide range of physiologic systems such as stress response, immune response and regulation of inflammation, carbohydrate metabolism, protein catabolism, blood electrolyte levels, and behavior. They include glucocorticoids and mineralocorticoids.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2009-12-11T03:52:07Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0071384") -AnnotationAssertion(rdfs:label "cellular response to corticosteroid stimulus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cellular response to glucocorticoid stimulus) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucocorticoid stimulus. Glucocorticoids are hormonal C21 corticosteroids synthesized from cholesterol with the ability to bind with the cortisol receptor and trigger similar effects. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2009-12-11T03:53:56Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0071385") -AnnotationAssertion(rdfs:label "cellular response to glucocorticoid stimulus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cellular response to mineralocorticoid stimulus) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mineralocorticoid stimulus. Mineralocorticoids are hormonal C21 corticosteroids synthesized from cholesterol and characterized by their similarity to aldosterone. Mineralocorticoids act primarily on water and electrolyte balance.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2009-12-11T03:59:02Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0071389") -AnnotationAssertion(rdfs:label "cellular response to mineralocorticoid stimulus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cellular response to progesterone stimulus) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a progesterone stimulus.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2009-12-11T04:11:13Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0071393") -AnnotationAssertion(rdfs:label "cellular response to progesterone stimulus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cellular response to testosterone stimulus) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a testosterone stimulus.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2009-12-11T04:11:29Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0071394") -AnnotationAssertion(rdfs:label "cellular response to testosterone stimulus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cellular response to lipid) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid stimulus.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2009-12-11T04:37:10Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0071396") -AnnotationAssertion(rdfs:label "cellular response to lipid") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (cellular response to fatty acid) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fatty acid stimulus.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2009-12-11T04:39:56Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0071398") -AnnotationAssertion(rdfs:label "cellular response to fatty acid") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cellular response to organic cyclic compound) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2009-12-14T02:55:58Z") -AnnotationAssertion(Annotation( "GOC:mah") "cellular response to organic cyclic substance") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0071407") -AnnotationAssertion(rdfs:label "cellular response to organic cyclic compound") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (cellular response to organonitrogen compound) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organonitrogen stimulus. An organonitrogen compound is formally a compound containing at least one carbon-nitrogen bond.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2009-12-14T04:07:27Z") -AnnotationAssertion(Annotation( "GOC:mah") "cellular response to organic nitrogen") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0071417") -AnnotationAssertion(rdfs:label "cellular response to organonitrogen compound") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (cellular response to amine stimulus) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amine stimulus. An amine is a compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2009-12-14T04:08:17Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0071418") -AnnotationAssertion(rdfs:label "cellular response to amine stimulus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cellular response to histamine) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a histamine stimulus. Histamine, the biogenic amine 2-(1H-imidazol-4-yl)ethanamine, is involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2009-12-14T04:09:25Z") -AnnotationAssertion(Annotation( "GOC:mah") "cellular response to histamine stimulus") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0071420") -AnnotationAssertion(rdfs:label "cellular response to histamine") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (hematopoietic stem cell proliferation) - -AnnotationAssertion(Annotation( "CL:0000037") Annotation( "GOC:BHF") Annotation( "GOC:add") Annotation( "GOC:mah") Annotation( "GOC:rl") "The expansion of a hematopoietic stem cell population by cell division. A hematopoietic stem cell is a stem cell from which all cells of the lymphoid and myeloid lineages develop.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2009-12-16T10:22:52Z") -AnnotationAssertion( "hemopoietic stem cell proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0071425") -AnnotationAssertion(rdfs:label "hematopoietic stem cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cellular response to water stimulus) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of water.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2009-12-18T11:32:44Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0071462") -AnnotationAssertion(rdfs:label "cellular response to water stimulus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (cellular response to endogenous stimulus) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus arising within the organism.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2009-12-18T02:25:40Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0071495") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.") -AnnotationAssertion(rdfs:label "cellular response to endogenous stimulus") -SubClassOf( ) - -# Class: (dopaminergic neuron differentiation) - -AnnotationAssertion(Annotation( "GOC:rph") "The process in which a neuroblast acquires the specialized structural and functional features of a dopaminergic neuron, a neuron that secretes dopamine.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-01-12T02:28:44Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0071542") -AnnotationAssertion(rdfs:label "dopaminergic neuron differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (cement gland development) - -AnnotationAssertion(Annotation( "GOC:bf") "The process whose specific outcome is the progression of the cement gland over time, from its formation to the mature structure. The cement gland is a simple mucus-secreting organ positioned at the anterior of amphibious embryos. The cement gland attaches the newly hatched embryo to a support before the hatchling can swim well or feed.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-01-20T04:31:04Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0071570") -AnnotationAssertion(rdfs:label "cement gland development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (otic vesicle development) - -AnnotationAssertion(Annotation( "GOC:mah") "The process whose specific outcome is the progression of the otic vesicle over time, from its formation to the mature structure. The otic vesicle is a transient embryonic structure formed during development of the vertebrate inner ear.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-02-04T04:07:17Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0071599") -AnnotationAssertion(rdfs:label "otic vesicle development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (otic vesicle morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mah") "The process in which the anatomical structures of the otic vesicle are generated and organized. The otic vesicle is a transient embryonic structure formed during development of the vertebrate inner ear.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-02-04T04:07:27Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0071600") -AnnotationAssertion(rdfs:label "otic vesicle morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (granulocyte chemotaxis) - -AnnotationAssertion(Annotation( "GOC:rph") "The movement of a granulocyte in response to an external stimulus.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-02-09T04:08:17Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0071621") -AnnotationAssertion(rdfs:label "granulocyte chemotaxis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of granulocyte chemotaxis) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the rate, frequency or extent of granulocyte chemotaxis. Granulocyte chemotaxis is the movement of a granulocyte in response to an external stimulus.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-02-09T04:09:24Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0071622") -AnnotationAssertion(rdfs:label "regulation of granulocyte chemotaxis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of granulocyte chemotaxis) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that decreases the rate, frequency or extent of granulocyte chemotaxis. Granulocyte chemotaxis is the movement of a granulocyte in response to an external stimulus.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-02-09T04:13:19Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0071623") -AnnotationAssertion(rdfs:label "negative regulation of granulocyte chemotaxis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of granulocyte chemotaxis) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that increases the rate, frequency or extent of granulocyte chemotaxis. Granulocyte chemotaxis is the movement of a granulocyte in response to an external stimulus.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-02-09T04:15:36Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0071624") -AnnotationAssertion(rdfs:label "positive regulation of granulocyte chemotaxis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (vocalization behavior) AnnotationAssertion(Annotation( "GOC:mah") "The behavior in which an organism produces sounds by a mechanism involving its respiratory system.") @@ -105798,107 +27326,6 @@ AnnotationAssertion( "mastication") SubClassOf( ) -# Class: (smooth muscle cell chemotaxis) - -AnnotationAssertion(Annotation( "GOC:mah") "The directed movement of a smooth muscle cell in response to an external stimulus.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-02-16T01:32:59Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0071670") -AnnotationAssertion(rdfs:label "smooth muscle cell chemotaxis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of smooth muscle cell chemotaxis) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate, or extent of smooth muscle cell chemotaxis.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-02-16T01:42:03Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0071671") -AnnotationAssertion(rdfs:label "regulation of smooth muscle cell chemotaxis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of smooth muscle cell chemotaxis) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate, or extent of smooth muscle cell chemotaxis.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-02-16T01:44:28Z") -AnnotationAssertion(Annotation( "GOC:mah") "down regulation of smooth muscle cell chemotaxis") -AnnotationAssertion(Annotation( "GOC:mah") "down-regulation of smooth muscle cell chemotaxis") -AnnotationAssertion(Annotation( "GOC:mah") "downregulation of smooth muscle cell chemotaxis") -AnnotationAssertion(Annotation( "GOC:mah") "inhibition of smooth muscle cell chemotaxis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0071672") -AnnotationAssertion(rdfs:label "negative regulation of smooth muscle cell chemotaxis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of smooth muscle cell chemotaxis) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate, or extent of smooth muscle cell chemotaxis.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-02-16T01:48:14Z") -AnnotationAssertion(Annotation( "GOC:mah") "up regulation of smooth muscle cell chemotaxis") -AnnotationAssertion(Annotation( "GOC:mah") "up-regulation of smooth muscle cell chemotaxis") -AnnotationAssertion(Annotation( "GOC:mah") "upregulation of smooth muscle cell chemotaxis") -AnnotationAssertion(Annotation( "GOC:mah") "activation of smooth muscle cell chemotaxis") -AnnotationAssertion(Annotation( "GOC:mah") "stimulation of smooth muscle cell chemotaxis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0071673") -AnnotationAssertion(rdfs:label "positive regulation of smooth muscle cell chemotaxis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (mononuclear cell migration) - -AnnotationAssertion(Annotation( "GOC:mah") "The movement of a mononuclear cell within or between different tissues and organs of the body.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-02-16T02:11:00Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0071674") -AnnotationAssertion(rdfs:label "mononuclear cell migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of mononuclear cell migration) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the rate, frequency or extent of mononuclear cell migration. Mononuclear cell migration is the movement of a mononuclear cell within or between different tissues and organs of the body.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-02-16T02:11:53Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0071675") -AnnotationAssertion(rdfs:label "regulation of mononuclear cell migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of mononuclear cell migration) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that decreases the rate, frequency or extent of mononuclear cell migration. Mononuclear cell migration is the movement of a mononuclear cell within or between different tissues and organs of the body.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-02-16T02:13:55Z") -AnnotationAssertion(Annotation( "GOC:mah") "down regulation of mononuclear cell migration") -AnnotationAssertion(Annotation( "GOC:mah") "down-regulation of mononuclear cell migration") -AnnotationAssertion(Annotation( "GOC:mah") "downregulation of mononuclear cell migration") -AnnotationAssertion(Annotation( "GOC:mah") "inhibition of mononuclear cell migration") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0071676") -AnnotationAssertion(rdfs:label "negative regulation of mononuclear cell migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of mononuclear cell migration) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that increases the rate, frequency or extent of mononuclear cell migration. Mononuclear cell migration is the movement of a mononuclear cell within or between different tissues and organs of the body.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-02-16T02:15:29Z") -AnnotationAssertion(Annotation( "GOC:mah") "up regulation of mononuclear cell migration") -AnnotationAssertion(Annotation( "GOC:mah") "up-regulation of mononuclear cell migration") -AnnotationAssertion(Annotation( "GOC:mah") "upregulation of mononuclear cell migration") -AnnotationAssertion(Annotation( "GOC:mah") "activation of mononuclear cell migration") -AnnotationAssertion(Annotation( "GOC:mah") "stimulation of mononuclear cell migration") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0071677") -AnnotationAssertion(rdfs:label "positive regulation of mononuclear cell migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (organism emergence from protective structure) AnnotationAssertion(Annotation( "GOC:mah") "The developmental process in which an organism emerges from a surrounding protective structure such as an egg or pupa case.") @@ -105909,91 +27336,6 @@ AnnotationAssertion( "organism emergence from protective structure") SubClassOf( ) -# Class: (protein localization to extracellular region) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process in which a protein is transported from one specific location in the extracellular region to another, or maintained in a specific extracellular location.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-02-25T04:00:13Z") -AnnotationAssertion(Annotation( "GOC:mah") "protein localisation in extracellular region") -AnnotationAssertion( "protein localization in extracellular region") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0071692") -AnnotationAssertion(rdfs:label "protein localization to extracellular region") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (anatomical structure maturation) - -AnnotationAssertion(Annotation( "GOC:mah") "A developmental process, independent of morphogenetic (shape) change, that is required for an anatomical structure to attain its fully functional state.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-03-02T11:43:38Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0071695") -AnnotationAssertion(rdfs:label "anatomical structure maturation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (ectodermal placode development) - -AnnotationAssertion(Annotation( "GOC:mah") "The progression of an ectodermal placode over time from its initial formation until its mature state. An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-03-02T11:48:01Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0071696") -AnnotationAssertion(rdfs:label "ectodermal placode development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (ectodermal placode morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mah") "The process in which the anatomical structures of an ectodermal placode are generated and organized. An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-03-02T11:49:51Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0071697") -AnnotationAssertion(rdfs:label "ectodermal placode morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (olfactory placode development) - -AnnotationAssertion(Annotation( "GOC:mah") "The progression of the olfactory placode over time from its initial formation until its mature state. The olfactory placode is a thickening of the neural ectoderm in the head region of the vertebrate embryo which develops into the olfactory region of the nasal cavity.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-03-02T12:45:14Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0071698") -AnnotationAssertion(rdfs:label "olfactory placode development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (olfactory placode morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mah") "The process in which the anatomical structures of the olfactory placode are generated and organized. The olfactory placode is a thickening of the neural ectoderm in the head region of the vertebrate embryo which develops into the olfactory region of the nasal cavity.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-03-02T12:45:45Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0071699") -AnnotationAssertion(rdfs:label "olfactory placode morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (olfactory placode maturation) - -AnnotationAssertion(Annotation( "GOC:mah") "A developmental process, independent of morphogenetic (shape) change, that is required for the olfactory placode to attain its fully functional state. The olfactory placode is a thickening of the neural ectoderm in the head region of the vertebrate embryo which develops into the olfactory region of the nasal cavity.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-03-02T01:10:54Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0071700") -AnnotationAssertion(rdfs:label "olfactory placode maturation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (organic substance transport) AnnotationAssertion(Annotation( "GOC:mah") "The directed movement of organic substances into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore. An organic substance is a molecular entity that contains carbon.") @@ -106002,7 +27344,6 @@ AnnotationAssertion( AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0071702") AnnotationAssertion(rdfs:label "organic substance transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (organic substance metabolic process) @@ -106015,7 +27356,6 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0071704") AnnotationAssertion(rdfs:label "organic substance metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) # Class: (nitrogen compound transport) @@ -106026,215 +27366,8 @@ AnnotationAssertion( AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0071705") AnnotationAssertion(rdfs:label "nitrogen compound transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (immunoglobulin heavy chain V-D-J recombination) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") "The process in which immunoglobulin heavy chain V, D, and J gene segments are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS).") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-03-09T04:20:31Z") -AnnotationAssertion(Annotation( "GOC:add") "immunoglobulin V(D)J joining") -AnnotationAssertion(Annotation( "GOC:add") "immunoglobulin V(D)J recombination") -AnnotationAssertion(Annotation( "GOC:add") "immunoglobulin V-D-J joining") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0071707") -AnnotationAssertion(rdfs:label "immunoglobulin heavy chain V-D-J recombination") -SubClassOf( ) - -# Class: (immunoglobulin light chain V-J recombination) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") "The process in which immunoglobulin light chain V and J gene segments are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS).") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-03-09T04:22:29Z") -AnnotationAssertion(Annotation( "GOC:add") "immunoglobulin V(D)J joining") -AnnotationAssertion(Annotation( "GOC:add") "immunoglobulin V(D)J recombination") -AnnotationAssertion(Annotation( "GOC:add") "immunoglobulin V-J joining") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0071708") -AnnotationAssertion(rdfs:label "immunoglobulin light chain V-J recombination") -SubClassOf( ) - -# Class: (membrane assembly) - -AnnotationAssertion(Annotation( "GOC:mah") "The aggregation, arrangement and bonding together of a set of components to form a membrane.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-03-10T11:19:17Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0071709") -AnnotationAssertion(rdfs:label "membrane assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (basement membrane organization) - -AnnotationAssertion(Annotation( "GOC:mah") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the basement membrane.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-03-10T11:57:10Z") -AnnotationAssertion(Annotation( "GOC:mah") "basement membrane organisation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0071711") -AnnotationAssertion(rdfs:comment "Note that this term has no relationship to 'membrane organization ; GO:0061024' because the basement membrane is not a lipid bilayer.") -AnnotationAssertion(rdfs:label "basement membrane organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (beak development) - -AnnotationAssertion(Annotation( "GOC:lp") Annotation( "ISBN:0702008729") "The progression of the beak over time from its initial formation until its mature state. The avian beak is an external anatomical structure, in the head region, that is adapted for feeding self and young, catching prey, probing, etc. It encompasses, but is not restricted to, the maxilla, mandible, maxillary rhamphotheca, mandibular rhamphotheca, nostril, nasal fossa, nasal bones, egg tooth and rictus.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-03-17T03:52:48Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0071728") -AnnotationAssertion(rdfs:label "beak development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (beak morphogenesis) - -AnnotationAssertion(Annotation( "GOC:lp") Annotation( "ISBN:0702008729") "The process in which the anatomical structures of the beak are generated and organized. The avian beak is an external anatomical structure, in the head region, that is adapted for feeding self and young, catching prey, probing, etc. It encompasses, but is not restricted to, the maxilla, mandible, maxillary rhamphotheca, mandibular rhamphotheca, nostril, nasal fossa, nasal bones, egg tooth and rictus.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-03-17T03:54:34Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0071729") -AnnotationAssertion(rdfs:label "beak morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (beak formation) - -AnnotationAssertion(Annotation( "GOC:lp") Annotation( "ISBN:0702008729") "The process that gives rise to the beak. This process pertains to the initial formation of a structure from unspecified parts. The avian beak is an external anatomical structure, in the head region, that is adapted for feeding self and young, catching prey, probing, etc. It encompasses, but is not restricted to, the maxilla, mandible, maxillary rhamphotheca, mandibular rhamphotheca, nostril, nasal fossa, nasal bones, egg tooth and rictus.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-03-17T03:57:07Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0071730") -AnnotationAssertion(rdfs:label "beak formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (IgG immunoglobulin complex) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781765196") "A protein complex composed of two identical immunoglobulin heavy chains of an IgG isotype and two identical immunoglobulin light chains, held together by disulfide bonds. An IgG immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-03-24T01:44:53Z") -AnnotationAssertion(Annotation( "GOC:add") "IgG1") -AnnotationAssertion(Annotation( "GOC:add") "IgG2") -AnnotationAssertion(Annotation( "GOC:add") "IgG2a") -AnnotationAssertion(Annotation( "GOC:add") "IgG2b") -AnnotationAssertion(Annotation( "GOC:add") "IgG2c") -AnnotationAssertion(Annotation( "GOC:add") "IgG3") -AnnotationAssertion(Annotation( "GOC:add") "IgG4") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0071735") -AnnotationAssertion(rdfs:comment "Note that an IgG immunoglobulin complex has the function of antigen binding if a suitable antigen is available. Also, IgG isotypes vary by species.") -AnnotationAssertion(rdfs:label "IgG immunoglobulin complex") -SubClassOf( ) - -# Class: (IgD immunoglobulin complex) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781765196") Annotation( "PMID:11282392") "A protein complex composed of two identical immunoglobulin heavy chains of the IgD isotype and two identical immunoglobulin light chains, held together by disulfide bonds. An IgD immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-03-24T01:44:53Z") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0071738") -AnnotationAssertion(rdfs:comment "Note that an IgD immunoglobulin complex has the function of antigen binding if a suitable antigen is available.") -AnnotationAssertion(rdfs:label "IgD immunoglobulin complex") -SubClassOf( ) - -# Class: (IgE immunoglobulin complex) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781765196") "A protein complex composed of two identical immunoglobulin heavy chains of the IgE isotype and two identical immunoglobulin light chains, held together by disulfide bonds. An IgE immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-03-24T01:44:53Z") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0071742") -AnnotationAssertion(rdfs:comment "Note that an IgE immunoglobulin complex has the function of antigen binding if a suitable antigen is available.") -AnnotationAssertion(rdfs:label "IgE immunoglobulin complex") -SubClassOf( ) - -# Class: (IgA immunoglobulin complex) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781765196") Annotation( "PMID:16362985") "A protein complex composed of two identical immunoglobulin heavy chains of the IgA isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and sometimes complexed with J chain or J chain and secretory component. An IgA immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-03-24T01:44:53Z") -AnnotationAssertion(Annotation( "GOC:add") "IgA1 antibody") -AnnotationAssertion(Annotation( "GOC:add") "IgA2 antibody") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0071745") -AnnotationAssertion(rdfs:comment "Note that an IgA immunoglobulin complex has the function of antigen binding if a suitable antigen is available.") -AnnotationAssertion(rdfs:label "IgA immunoglobulin complex") -SubClassOf( ) - -# Class: (IgM immunoglobulin complex) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781765196") Annotation( "PMID:20176268") "A protein complex composed of two identical immunoglobulin heavy chains of the IgM isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and in its circulating form complexed with J chain in polymeric forms. An IgM immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-03-24T01:44:53Z") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0071753") -AnnotationAssertion(rdfs:comment "Note that an IgM immunoglobulin complex has the function of antigen binding if a suitable antigen is available.") -AnnotationAssertion(rdfs:label "IgM immunoglobulin complex") -SubClassOf( ) - -# Class: (nuclear membrane organization) - -AnnotationAssertion(Annotation( "GOC:mah") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear inner or outer membrane.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-03-29T03:59:35Z") -AnnotationAssertion(Annotation( "GOC:mah") "nuclear membrane organisation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:mah") "nuclear membrane organization and biogenesis") -AnnotationAssertion( "GO:0071763") -AnnotationAssertion(rdfs:label "nuclear membrane organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (nuclear outer membrane organization) - -AnnotationAssertion(Annotation( "GOC:mah") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear outer membrane.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-03-29T04:03:37Z") -AnnotationAssertion(Annotation( "GOC:mah") "nuclear outer membrane organisation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:mah") "nuclear outer membrane organization and biogenesis") -AnnotationAssertion( "GO:0071764") -AnnotationAssertion(rdfs:label "nuclear outer membrane organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (protein transmembrane transport) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:vw") "The process in which a protein is transported across a membrane.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-09-03T02:54:26Z") -AnnotationAssertion( "protein membrane transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0071806") -AnnotationAssertion(rdfs:comment "Note that this term is not intended for use in annotating lateral movement within membranes.") -AnnotationAssertion(rdfs:label "protein transmembrane transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (protein-DNA complex organization) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein-DNA complex.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-09-08T10:03:26Z") -AnnotationAssertion(Annotation( "GOC:mah") "DNA-protein complex subunit organization") -AnnotationAssertion(Annotation( "GOC:mah") "protein-DNA complex subunit organisation") -AnnotationAssertion( "protein-DNA complex subunit organization") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0071824") -AnnotationAssertion(rdfs:label "protein-DNA complex organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (protein-RNA complex organization) AnnotationAssertion(Annotation( "GOC:mah") "Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a ribonucleoprotein complex.") @@ -106248,7 +27381,6 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0071826") AnnotationAssertion(rdfs:label "protein-RNA complex organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (mating pheromone secretion) @@ -106277,165 +27409,6 @@ AnnotationAssertion( "cellular component organization or biogenesis") SubClassOf( ) -# Class: (response to monoamine) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monoamine stimulus. A monoamine is any of a group of molecular messengers that contain one amino group that is connected to an aromatic ring by ethylene group (-CH2-CH2-). Monoamines are derived from the aromatic amino acids phenylalanine, tyrosine, histidine and tryptophan.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-09-13T02:36:37Z") -AnnotationAssertion(Annotation( "GOC:dos") "response to monoamine stimulus") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0071867") -AnnotationAssertion(rdfs:label "response to monoamine") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cellular response to monoamine stimulus) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monoamine stimulus. A monoamine is any of a group of molecular messengers that contain one amino group that is connected to an aromatic ring by ethylene group (-CH2-CH2-). Monoamines are derived from the aromatic amino acids phenylalanine, tyrosine, histidine and tryptophan.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-09-13T02:38:52Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0071868") -AnnotationAssertion(rdfs:label "cellular response to monoamine stimulus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (response to catecholamine) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a catecholamine stimulus. A catecholamine is any of a group of biogenic amines that includes 4-(2-aminoethyl)pyrocatechol [4-(2-aminoethyl)benzene-1,2-diol] and derivatives formed by substitution.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-09-13T02:51:13Z") -AnnotationAssertion(Annotation( "GOC:dos") "response to catecholamine stimulus") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0071869") -AnnotationAssertion(rdfs:label "response to catecholamine") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cellular response to catecholamine stimulus) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a catecholamine stimulus. A catecholamine is any of a group of biogenic amines that includes 4-(2-aminoethyl)pyrocatechol [4-(2-aminoethyl)benzene-1,2-diol] and derivatives formed by substitution.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-09-13T02:54:50Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0071870") -AnnotationAssertion(rdfs:label "cellular response to catecholamine stimulus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (response to epinephrine) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epinephrine stimulus. Epinephrine is a catecholamine that has the formula C9H13NO3; it is secreted by the adrenal medulla to act as a hormone, and released by certain neurons to act as a neurotransmitter active in the central nervous system.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-09-13T03:27:48Z") -AnnotationAssertion(Annotation( "GOC:mah") "response to adrenaline stimulus") -AnnotationAssertion(Annotation( "GOC:dos") "response to epinephrine stimulus") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0071871") -AnnotationAssertion(rdfs:comment "Note that epinephrine and norepinephrine are ligands for the same receptors, and there are multiple adrenergic receptors.") -AnnotationAssertion(rdfs:label "response to epinephrine") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cellular response to epinephrine stimulus) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epinephrine stimulus. Epinephrine is a catecholamine that has the formula C9H13NO3; it is secreted by the adrenal medulla to act as a hormone, and released by certain neurons to act as a neurotransmitter active in the central nervous system.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-09-13T03:31:40Z") -AnnotationAssertion(Annotation( "GOC:mah") "cellular response to adrenaline stimulus") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0071872") -AnnotationAssertion(rdfs:comment "Note that epinephrine and norepinephrine are ligands for the same receptors, and there are multiple adrenergic receptors.") -AnnotationAssertion(rdfs:label "cellular response to epinephrine stimulus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (response to norepinephrine) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a norepinephrine stimulus. Norepinephrine is a catecholamine that has the formula C8H11NO3; it acts as a hormone, and as a neurotransmitter in most of the sympathetic nervous system.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-09-13T03:31:53Z") -AnnotationAssertion(Annotation( "GOC:mah") "response to noradrenaline stimulus") -AnnotationAssertion(Annotation( "GOC:dos") "response to norepinephrine stimulus") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0071873") -AnnotationAssertion(rdfs:comment "Note that epinephrine and norepinephrine are ligands for the same receptors, and there are multiple adrenergic receptors.") -AnnotationAssertion(rdfs:label "response to norepinephrine") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cellular response to norepinephrine stimulus) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a norepinephrine stimulus. Norepinephrine is a catecholamine that has the formula C8H11NO3; it acts as a hormone, and as a neurotransmitter in most of the sympathetic nervous system.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-09-13T03:33:32Z") -AnnotationAssertion(Annotation( "GOC:mah") "cellular response to noradrenaline stimulus") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0071874") -AnnotationAssertion(rdfs:comment "Note that epinephrine and norepinephrine are ligands for the same receptors, and there are multiple adrenergic receptors.") -AnnotationAssertion(rdfs:label "cellular response to norepinephrine stimulus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (leukocyte apoptotic process) - -AnnotationAssertion(Annotation( "CL:0000738") Annotation( "GOC:BHF") Annotation( "GOC:mah") Annotation( "GOC:mtg_apoptosis") "Any apoptotic process in a leukocyte, an achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-09-14T12:44:09Z") -AnnotationAssertion( "leukocyte apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0071887") -AnnotationAssertion(rdfs:comment "Note that a lymphocyte is a cell of the B cell, T cell, or natural killer cell lineage (CL:0000542).") -AnnotationAssertion(rdfs:label "leukocyte apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - -# Class: (macrophage apoptotic process) - -AnnotationAssertion(Annotation( "CL:0000235") Annotation( "GOC:BHF") Annotation( "GOC:mah") Annotation( "GOC:mtg_apoptosis") "Any apoptotic process in a macrophage, a mononuclear phagocyte present in a variety of tissues.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-09-14T12:50:40Z") -AnnotationAssertion( "macrophage apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:yaf") "AICD") -AnnotationAssertion(Annotation( "GOC:yaf") "activation-induced cell death") -AnnotationAssertion( "GO:0071888") -AnnotationAssertion(rdfs:comment "Note that a lymphocyte is a cell of the B cell, T cell, or natural killer cell lineage (CL:0000542).") -AnnotationAssertion(rdfs:label "macrophage apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (bicarbonate binding) - -AnnotationAssertion(Annotation( "GOC:curators") "Binding to bicarbonate ions (CHO3-).") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-09-14T01:47:43Z") -AnnotationAssertion( "CHO3- ion binding binding") -AnnotationAssertion(Annotation( "CHEBI:17544") "hydrogencarbonate binding") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0071890") -AnnotationAssertion(rdfs:label "bicarbonate binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (odontoblast differentiation) - -AnnotationAssertion(Annotation( "GOC:sl") Annotation( "PMID:20425127") "The process in which a relatively unspecialized cell of neural crest origin acquires the specialized features of an odontoblast, a cell on the outer surface of the dental pulp whose biological function is the creation of dentin.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-09-14T04:00:40Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0071895") -AnnotationAssertion(rdfs:label "odontoblast differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (DNA biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:mah") "The biosynthetic process resulting in the formation of DNA.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-09-15T02:14:33Z") -AnnotationAssertion(Annotation( "GOC:mah") "DNA anabolism") -AnnotationAssertion(Annotation( "GOC:mah") "DNA biosynthesis") -AnnotationAssertion(Annotation( "GOC:mah") "DNA formation") -AnnotationAssertion(Annotation( "GOC:mah") "DNA synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0071897") -AnnotationAssertion(rdfs:label "DNA biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (cell periphery) AnnotationAssertion(Annotation( "GOC:pdt") "The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures.") @@ -106460,1436 +27433,6 @@ AnnotationAssertion(rdfs:label "elas SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (extracellular exosome assembly) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:tfm") Annotation( "PMID:19442504") Annotation( "PMID:27462458") "The aggregation, arrangement and bonding together of a set of components to form an extracellular vesicular exosome, a membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Exosomes are defined by their size, which generally ranges from 30 nm to 100 nm.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-10-18T03:44:18Z") -AnnotationAssertion(Annotation( "GOC:vesicles") "extracellular vesicular exosome assembly") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0071971") -AnnotationAssertion(rdfs:label "extracellular exosome assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (renal system development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") Annotation( "GOC:yaf") Annotation( "http://en.wikibooks.org/wiki/Human_Physiology/The_Urinary_System") "The process whose specific outcome is the progression of the renal system over time, from its formation to the mature structure. The renal system maintains fluid balance and contributes to electrolyte balance, acid/base balance, and disposal of nitrogenous waste products. In humans, the renal system comprises a pair of kidneys, a pair of ureters, urinary bladder, urethra, sphincter muscle and associated blood vessels.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-01-25T10:31:00Z") -AnnotationAssertion(Annotation( "GOC:yaf") "urinary system development") -AnnotationAssertion(Annotation( "GOC:yaf") Annotation( "PMID:17881463") "urinary tract development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072001") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "renal system development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (Malpighian tubule development) - -AnnotationAssertion(Annotation( "FBbt:00005786") Annotation( "GOC:mtg_kidney_jan10") Annotation( "PMID:19783135") "The process whose specific outcome is the progression of the Malpighian tubule over time, from its formation to the mature structure. A Malpighian tubule is a fine, thin-walled excretory tubule in insects which leads into the posterior part of the gut.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-01-25T10:54:30Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072002") -AnnotationAssertion(rdfs:label "Malpighian tubule development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - -# Class: (kidney rudiment formation) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The developmental process pertaining to the initial formation of a kidney rudiment from unspecified parts. A kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-01-25T11:18:58Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "kidney anlage formation") -AnnotationAssertion( "GO:0072003") -AnnotationAssertion(rdfs:label "kidney rudiment formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (nephron development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the nephron over time, from its formation to the mature structure. A nephron is the functional unit of the kidney.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-01-25T01:37:16Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:rph") "nephrogenesis") -AnnotationAssertion( "GO:0072006") -AnnotationAssertion(rdfs:label "nephron development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (mesangial cell differentiation) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesangial cells of the kidney as it progresses from its formation to the mature state.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-01-25T01:59:09Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072007") -AnnotationAssertion(rdfs:label "mesangial cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (nephron epithelium development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the nephron epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The nephron epithelium is a tissue that covers the surface of a nephron.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-01-25T02:01:39Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072009") -AnnotationAssertion(rdfs:label "nephron epithelium development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (glomerular epithelium development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the glomerular epithelium over time, from its formation to the mature structure. The glomerular epithelium is an epithelial tissue that covers the outer surfaces of the glomerulus. The glomerular epithelium consists of both parietal and visceral epithelium. Metanephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the metanephros.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-01-25T02:02:14Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072010") -AnnotationAssertion(rdfs:label "glomerular epithelium development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (glomerular endothelium development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the glomerular endothelium over time, from its formation to the mature structure. The glomerular endothelium is an epithelial tissue that covers the internal surfaces of the glomerulus.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-01-25T02:02:57Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072011") -AnnotationAssertion(rdfs:label "glomerular endothelium development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (glomerulus vasculature development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The biological process whose specific outcome is the progression of a glomerulus vasculature from an initial condition to its mature state. This process begins with the formation of the glomerulus vasculature and ends with the mature structure. The glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the glomerulus.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-01-25T02:05:04Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "glomerulus capillary development") -AnnotationAssertion( "GO:0072012") -AnnotationAssertion(rdfs:label "glomerulus vasculature development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (proximal tubule development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the proximal tubule over time, from its formation to the mature structure. In mammals, the proximal tubule is a nephron tubule that connects Bowman's capsule to the descending thin limb of the loop of Henle. It has a brush border epithelial morphology.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-01-25T02:33:46Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072014") -AnnotationAssertion(rdfs:label "proximal tubule development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (podocyte development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of a glomerular visceral epithelial cell over time, from its formation to the mature structure. A glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/23000"^^xsd:anyURI) -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-01-25T02:12:45Z") -AnnotationAssertion( "glomerular visceral epithelial cell development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072015") -AnnotationAssertion(rdfs:label "podocyte development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (glomerular parietal epithelial cell development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of a glomerular parietal epithelial cell over time, from its formation to the mature structure. Glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-01-25T02:13:16Z") -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "Bowman's capsule development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072016") -AnnotationAssertion(rdfs:label "glomerular parietal epithelial cell development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (distal tubule development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the distal tubule over time, from its formation to the mature structure. In mammals, the distal tubule is a nephron tubule that begins at the macula densa and extends to the connecting tubule.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-01-25T02:34:19Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072017") -AnnotationAssertion(rdfs:label "distal tubule development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (proximal convoluted tubule development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the proximal convoluted tubule over time, from its formation to the mature structure. The proximal convoluted tubule is the most proximal portion of the proximal tubule and extends from the glomerular capsule to the proximal straight tubule.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-01-25T02:35:35Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072019") -AnnotationAssertion(rdfs:label "proximal convoluted tubule development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (proximal straight tubule development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the proximal straight tubule over time, from its formation to the mature structure. The proximal straight tubule is the part of the descending limb that extends from the proximal convoluted tubule to the descending thin tubule.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-01-25T02:36:14Z") -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "S3 development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072020") -AnnotationAssertion(rdfs:label "proximal straight tubule development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (ascending thin limb development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of an ascending thin limb over time, from its formation to the mature structure. The ascending thin limb is a segment of a nephron tubule lying in the inner medulla that is permeable to ions but not to water and has a simple epithelium; active transepithelial solute transport is absent.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-01-25T02:37:13Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072021") -AnnotationAssertion(rdfs:label "ascending thin limb development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (descending thin limb development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the descending thin limb over time, from its formation to the mature structure. The descending thin limb is a part of the loop of Henle situated just after the proximal straight tubule (S3). It extends to the tip of the loop of Henle.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-01-25T02:37:47Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072022") -AnnotationAssertion(rdfs:label "descending thin limb development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (thick ascending limb development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the thick ascending limb over time, from its formation to the mature structure. The thick ascending limb is the last part of the loop of Henle. Its thick, mitochondria-rich epithelium characterizes the outer medulla, and is responsible for very avid active salt transport. At the macula densa, the thick ascending limb connects to the distal convoluted tubule.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-01-25T02:39:51Z") -AnnotationAssertion( "GO:0072026") -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "TAL development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072023") -AnnotationAssertion(rdfs:label "thick ascending limb development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (macula densa development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the macula densa over time, from its formation to the mature structure. The macula densa is an area of specialized cells in the distal tubule that makes contact with the vascular pole of the glomerulus.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-01-25T02:40:15Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072024") -AnnotationAssertion(rdfs:label "macula densa development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (distal convoluted tubule development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the distal convoluted tubule over time, from its formation to the mature structure. The distal convoluted tubule is the first segment of the nephron lying just downstream from the loop of Henle, immediately after the macula densa. Among other functions, in humans it is responsible for the reabsorption of about 5% of filtered sodium via the thiazide-sensitive Na-Cl symporter.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-01-25T02:40:45Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072025") -AnnotationAssertion(rdfs:label "distal convoluted tubule development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (connecting tubule development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the connecting tubule over time, from its formation to the mature structure. The connecting tubule is a tubular segment of the nephron; it connects the distal convoluted tubule to the collecting duct.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-01-25T02:42:05Z") -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "connecting duct development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072027") -AnnotationAssertion(rdfs:label "connecting tubule development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (nephron morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the anatomical structures of the nephron are generated and organized. A nephron is the functional unit of the kidney.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-01-25T02:45:52Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072028") -AnnotationAssertion(rdfs:label "nephron morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (long nephron development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of a long nephron over time, from its formation to the mature structure. Long nephrons are associated with juxtamedullary glomeruli and extend into the inner medulla.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-01-25T02:49:08Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "juxtamedullary nephron development") -AnnotationAssertion( "GO:0072029") -AnnotationAssertion(rdfs:label "long nephron development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (short nephron development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of a short nephron over time, from its formation to the mature structure. Short nephrons are associated with mid-cortical and superficial glomeruli, are situated entirely in the outer medulla, and have no thin ascending limb.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-01-25T02:49:32Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072030") -AnnotationAssertion(rdfs:label "short nephron development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (proximal convoluted tubule segment 1 development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") Annotation( "MA:0002612") "The process whose specific outcome is the progression of the S1 portion of the proximal convoluted tubule over time, from its formation to the mature structure. The S1 portion is the initial portion of the proximal convoluted tubule and is responsible for avid reabsorption of water and solutes.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-01-25T02:55:57Z") -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "S1 development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072031") -AnnotationAssertion(rdfs:label "proximal convoluted tubule segment 1 development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (proximal convoluted tubule segment 2 development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") Annotation( "MA:0002613") "The process whose specific outcome is the progression of the S2 portion of the proximal convoluted tubule over time, from its formation to the mature structure. The S2 portion of the tubule is involved in reabsorption of water and sodium chloride.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-01-25T02:56:36Z") -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "S2 development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072032") -AnnotationAssertion(rdfs:label "proximal convoluted tubule segment 2 development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (renal vesicle formation) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The developmental process pertaining to the initial formation of the renal vesicle from condensed mesenchymal cells. The renal vesicle is the primordial structure of the nephron epithelium, and is formed by the condensation of mesenchymal cells.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-01-25T02:57:03Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "nephron epithelium formation") -AnnotationAssertion( "GO:0072033") -AnnotationAssertion(rdfs:label "renal vesicle formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (mesenchymal to epithelial transition involved in renal vesicle formation) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the renal vesicle.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-01-25T03:04:24Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072036") -AnnotationAssertion(rdfs:label "mesenchymal to epithelial transition involved in renal vesicle formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (mesenchymal stem cell maintenance involved in nephron morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which an organism retains a population of mesenchymal stem cells that contributes to the shaping of a nephron. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-01-25T03:08:05Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072038") -AnnotationAssertion(rdfs:label "mesenchymal stem cell maintenance involved in nephron morphogenesis") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:mtg_kidney_jan10") "Any process that modulates the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-01-25T03:08:34Z") -AnnotationAssertion( "regulation of mesenchymal stem cell apoptotic process involved in nephron morphogenesis") -AnnotationAssertion( "regulation of mesenchymal stem cell apoptosis involved in nephron morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072039") -AnnotationAssertion(rdfs:label "regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:mtg_kidney_jan10") "Any process that reduces the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-01-25T03:09:30Z") -AnnotationAssertion( "negative regulation of mesenchymal stem cell apoptotic process involved in nephron morphogenesis") -AnnotationAssertion( "negative regulation of mesenchymal stem cell apoptosis involved in nephron morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072040") -AnnotationAssertion(rdfs:label "negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (positive regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:mtg_kidney_jan10") "Any process that increases the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-01-25T03:10:32Z") -AnnotationAssertion( "positive regulation of mesenchymal stem cell apoptotic process involved in nephron morphogenesis") -AnnotationAssertion( "positive regulation of mesenchymal stem cell apoptosis involved in nephron morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072041") -AnnotationAssertion(rdfs:label "positive regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (collecting duct development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of a collecting duct over time, from its formation to the mature structure. The collecting duct responds to vasopressin and aldosterone to regulate water, electrolyte and acid-base balance. It is the final common path through which urine flows before entering the ureter and then emptying into the bladder.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-01-25T03:18:06Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072044") -AnnotationAssertion(rdfs:label "collecting duct development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (renal system pattern specification) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "Any developmental process that results in the creation of defined areas or spaces within an organism to which cells respond and eventually are instructed to differentiate into the anatomical structures of the renal system.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-01-25T03:31:51Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "renal system pattern formation") -AnnotationAssertion( "GO:0072048") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "renal system pattern specification") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (comma-shaped body morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the comma-shaped body is generated and organized. The comma-shaped body is the precursor structure to the S-shaped body that contributes to the morphogenesis of the nephron.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-01-25T03:44:48Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072049") -AnnotationAssertion(rdfs:label "comma-shaped body morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (S-shaped body morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the S-shaped body is generated and organized. The S-shaped body is the successor of the comma-shaped body that contributes to the morphogenesis of the nephron.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-01-25T03:45:19Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072050") -AnnotationAssertion(rdfs:label "S-shaped body morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (juxtaglomerular apparatus development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the juxtaglomerular apparatus over time, from its formation to the mature structure. The juxtaglomerular apparatus is an anatomical structure that lies adjacent to the glomerulus and regulates kidney function.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-01-25T03:52:23Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072051") -AnnotationAssertion(rdfs:label "juxtaglomerular apparatus development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (juxtaglomerulus cell differentiation) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the juxtaglomerulus cells of the kidney as it progresses from its formation to the mature state.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-01-25T03:58:01Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072052") -AnnotationAssertion(rdfs:label "juxtaglomerulus cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (renal inner medulla development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the renal inner medulla over time, from its formation to the mature structure. The renal inner medulla is unique to mammalian kidneys and is the innermost region of the mammalian kidney.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-01-25T03:59:37Z") -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "inner renal medulla development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072053") -AnnotationAssertion(rdfs:label "renal inner medulla development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (renal outer medulla development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the renal outer medulla over time, from its formation to the mature structure. The renal outer medulla is the region of the kidney that lies between the renal cortex and the renal inner medulla.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-01-25T04:00:42Z") -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "outer renal medulla development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072054") -AnnotationAssertion(rdfs:label "renal outer medulla development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (renal cortex development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the renal cortex over time, from its formation to the mature structure. The renal cortex is the outer region of the kidney.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-01-25T04:01:12Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072055") -AnnotationAssertion(rdfs:label "renal cortex development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (pyramid development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the kidney pyramids over time, from its formation to the mature structure. Kidney pyramids are the conical masses that constitute the renal medulla in a multi-lobed mammalian kidney; they contain the loops of Henle and the medullary collecting ducts.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-01-25T04:01:36Z") -AnnotationAssertion(Annotation( "GOC:mah") "kidney pyramid development") -AnnotationAssertion(Annotation( "GOC:mah") "pyramids development") -AnnotationAssertion(Annotation( "GOC:mah") "renal medulla development") -AnnotationAssertion(Annotation( "GOC:mah") "renal pyramid development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072056") -AnnotationAssertion(rdfs:label "pyramid development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (inner stripe development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the inner stripe over time, from its formation to the mature structure. The inner stripe is a deep, centrally located portion of the renal outer medulla and is traversed by thin descending and thick ascending portions of the loops of Henle.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-01-25T04:01:58Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072057") -AnnotationAssertion(rdfs:label "inner stripe development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (outer stripe development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the outer stripe over time, from its formation to the mature structure. The outer stripe is the region of the kidney outer medulla that lies just below the cortex. The proximal straight tubules (S3) characterize this region.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-01-25T04:02:56Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072058") -AnnotationAssertion(rdfs:label "outer stripe development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cortical collecting duct development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the cortical collecting duct over time, from its formation to the mature structure. The cortical collecting duct is the portion of the collecting duct that resides in the renal cortex.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-01-25T04:07:07Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072059") -AnnotationAssertion(rdfs:label "cortical collecting duct development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (outer medullary collecting duct development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the outer medullary collecting duct over time, from its formation to the mature structure. The outer medullary collecting duct is the portion of the collecting duct that lies in the renal outer medulla.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-01-25T04:08:18Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072060") -AnnotationAssertion(rdfs:label "outer medullary collecting duct development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (inner medullary collecting duct development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the inner medullary collecting duct over time, from its formation to the mature structure. The inner medullary collecting duct is the portion of the collecting duct that lies in the renal inner medulla.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-01-25T04:08:45Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072061") -AnnotationAssertion(rdfs:label "inner medullary collecting duct development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (short descending thin limb development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the short descending thin limb over time, from its formation to the mature structure. The short descending thin limb is the descending thin limb of a short nephron that has a squamous epithelial morphology.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-01-25T04:12:39Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072063") -AnnotationAssertion(rdfs:label "short descending thin limb development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (long descending thin limb development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the long descending thin limb over time, from its formation to the mature structure. The long descending thin limb is the descending thin limb of a long nephron that has a squamous epithelial morphology. The long descending limb starts in the inner stripe of the outer medulla and extends into the inner medulla.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-01-25T04:13:17Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072064") -AnnotationAssertion(rdfs:label "long descending thin limb development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (long descending thin limb bend development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the long descending thin limb bend over time, from its formation to the mature structure. The long descending thin limb bend is a part of the descending thin limb of a long nephron that lies beyond the prebend segment.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-01-25T04:13:38Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072065") -AnnotationAssertion(rdfs:label "long descending thin limb bend development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (prebend segment development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the prebend segment over time, from its formation to the mature structure. The prebend segment is a part of the descending thin limb that lies before the bend and exhibits permeabilities characteristic of the ascending limb, especially negligible water permeability.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-01-25T04:14:02Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072066") -AnnotationAssertion(rdfs:label "prebend segment development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (early distal convoluted tubule development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the early distal convoluted tubule over time, from its formation to the mature structure. The early distal convoluted tubule contains DCT cells and is vasopressin-insensitive.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-01-25T04:15:17Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072067") -AnnotationAssertion(rdfs:label "early distal convoluted tubule development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (late distal convoluted tubule development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the late distal convoluted tubule over time, from its formation to the mature structure. The late distal convoluted tubule contains DCT cells and intercalated (IC) alpha and beta cells and is vasopressin-sensitive.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-01-25T04:15:50Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072068") -AnnotationAssertion(rdfs:label "late distal convoluted tubule development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (loop of Henle development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the loop of Henle over time, from its formation to the mature structure. The loop of Henle is a nephron tubule that connects the proximal convoluted tubule to the distal convoluted tubule.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-01-25T04:20:27Z") -AnnotationAssertion( "GO:0072018") -AnnotationAssertion( "intermediate tubule development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072070") -AnnotationAssertion(rdfs:label "loop of Henle development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (kidney interstitial fibroblast differentiation) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the interstitial fibroblast of the kidney as it progresses from its formation to the mature state.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-01-25T04:34:31Z") -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "kidney interstitial cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072071") -AnnotationAssertion(rdfs:label "kidney interstitial fibroblast differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (kidney epithelium development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of an epithelium in the kidney over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-01-25T04:37:42Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072073") -AnnotationAssertion(rdfs:label "kidney epithelium development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (kidney mesenchyme development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The biological process whose specific outcome is the progression of a kidney mesenchyme from an initial condition to its mature state. This process begins with the formation of kidney mesenchyme and ends with the mature structure. Kidney mesenchyme is the tissue made up of loosely connected mesenchymal cells in the kidney.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-01-25T04:39:04Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072074") -AnnotationAssertion(rdfs:label "kidney mesenchyme development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (metanephric mesenchyme development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The biological process whose specific outcome is the progression of a metanephric mesenchyme from an initial condition to its mature state. This process begins with the formation of metanephric mesenchyme and ends with the mature structure. Metanephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the metanephros.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-01-25T04:40:11Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072075") -AnnotationAssertion(rdfs:label "metanephric mesenchyme development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (nephrogenic mesenchyme development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The biological process whose specific outcome is the progression of a nephrogenic mesenchyme from an initial condition to its mature state. This process begins with the formation of nephrogenic mesenchyme and ends with the mature structure. Nephrogenic mesenchyme is the tissue made up of loosely connected mesenchymal cells in the nephron.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-01-25T04:40:44Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072076") -AnnotationAssertion(rdfs:label "nephrogenic mesenchyme development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (renal vesicle morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the anatomical structures of the renal vesicle are generated and organized. The renal vesicle is the primordial structure of the nephron epithelium, and is formed by the condensation of mesenchymal cells.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-02-01T02:21:06Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072077") -AnnotationAssertion(rdfs:label "renal vesicle morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (nephron tubule morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the anatomical structures of a nephron tubule are generated and organized. A nephron tubule is an epithelial tube that is part of the nephron, the functional part of the kidney.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-02-01T02:25:14Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072078") -AnnotationAssertion(rdfs:label "nephron tubule morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (nephron tubule formation) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The developmental process pertaining to the initial formation of a nephron tubule from unspecified parts. A nephron tubule is an epithelial tube that is part of the nephron, the functional part of the kidney.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-02-01T02:29:26Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072079") -AnnotationAssertion(rdfs:label "nephron tubule formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (nephron tubule development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The progression of a nephron tubule over time, from its initial formation to the mature structure. A nephron tubule is an epithelial tube that is part of the nephron, the functional part of the kidney.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-02-01T02:32:12Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072080") -AnnotationAssertion(rdfs:label "nephron tubule development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (renal vesicle development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the renal vesicle over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The renal vesicle is the primordial structure of the nephron epithelium, and is formed by the condensation of mesenchymal cells.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-02-08T01:18:31Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072087") -AnnotationAssertion(rdfs:label "renal vesicle development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (nephron epithelium morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the anatomical structures of the nephron epithelium are generated and organized. The nephron epithelium is a tissue that covers the surface of a nephron.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-02-08T01:19:06Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072088") -AnnotationAssertion(rdfs:label "nephron epithelium morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (stem cell proliferation) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The multiplication or reproduction of stem cells, resulting in the expansion of a stem cell population. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-02-08T02:03:36Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072089") -AnnotationAssertion(rdfs:label "stem cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (regulation of stem cell proliferation) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "Any process that modulates the frequency, rate or extent of stem cell proliferation. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-02-08T02:09:03Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072091") -AnnotationAssertion(rdfs:label "regulation of stem cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (metanephric renal vesicle formation) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The developmental process pertaining to the initial formation of the metanephros.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-02-10T01:17:11Z") -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "metanephros formation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072093") -AnnotationAssertion(rdfs:label "metanephric renal vesicle formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (anterior/posterior pattern specification involved in kidney development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The developmental process that results in the creation of defined areas or spaces within the kidney along the anterior/posterior axis to which cells respond and eventually are instructed to differentiate.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-02-10T02:06:24Z") -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "kidney anterior/posterior pattern specification") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "anterior/posterior pattern formation involved in kidney development") -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "kidney anterior/posterior pattern formation") -AnnotationAssertion( "GO:0072098") -AnnotationAssertion(rdfs:label "anterior/posterior pattern specification involved in kidney development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (anterior/posterior pattern specification involved in ureteric bud development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The developmental process that results in the creation of defined areas or spaces within the ureteric bud along the anterior/posterior axis to which cells respond and eventually are instructed to differentiate.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-02-10T02:12:09Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "ureteric bud anterior/posterior pattern formation") -AnnotationAssertion( "GO:0072099") -AnnotationAssertion(rdfs:label "anterior/posterior pattern specification involved in ureteric bud development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (glomerulus morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the anatomical structures of the glomerulus are generated and organized. The glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-02-10T02:32:09Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072102") -AnnotationAssertion(rdfs:label "glomerulus morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (glomerulus vasculature morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the anatomical structures of the glomerulus vasculature are generated and organized. The glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the glomerulus.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-02-10T02:34:54Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072103") -AnnotationAssertion(rdfs:label "glomerulus vasculature morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (glomerular capillary formation) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process that gives rise to a glomerular capillary. This process pertains to the initial formation of a structure from unspecified parts.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-02-10T02:40:40Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072104") -AnnotationAssertion(rdfs:label "glomerular capillary formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (ureteric peristalsis) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "A wavelike sequence of involuntary muscular contraction and relaxation that passes along the ureter, impelling the contents onwards. The ureter is one of a pair of thick-walled tubes that transports urine from the kidney pelvis to the urinary bladder.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-02-10T03:07:54Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072105") -AnnotationAssertion(rdfs:label "ureteric peristalsis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of ureteric bud formation) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "Any process that modulates the developmental process pertaining to the initial formation of the ureteric bud from the Wolffian duct.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-02-12T02:34:40Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072106") -AnnotationAssertion(rdfs:label "regulation of ureteric bud formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of ureteric bud formation) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "Any process that increases the rate or extent of the developmental process pertaining to the initial formation of the ureteric bud from the Wolffian duct.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-02-12T02:37:28Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072107") -AnnotationAssertion(rdfs:label "positive regulation of ureteric bud formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "Any process that increases the rate, frequency or extent of the transition where a mesenchymal cell establishes apical/basolateral polarity, forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-02-12T02:45:57Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072108") -AnnotationAssertion(rdfs:label "positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (glomerular mesangium development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the glomerular mesangium over time, from its formation to the mature structure. The glomerular mesangium is the thin membrane connective tissue composed of mesangial cells, which helps to support the capillary loops in a renal glomerulus.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-02-22T10:35:24Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072109") -AnnotationAssertion(rdfs:label "glomerular mesangium development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cell proliferation involved in kidney development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The multiplication or reproduction of cells, resulting in the expansion of the population in the kidney.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-02-22T10:48:45Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072111") -AnnotationAssertion(rdfs:label "cell proliferation involved in kidney development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (podocyte differentiation) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which a relatively unspecialized cell acquires specialized features of a glomerular visceral epithelial cell. A glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/23000"^^xsd:anyURI) -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-02-22T10:52:11Z") -AnnotationAssertion( "glomerular visceral epithelial cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072112") -AnnotationAssertion(rdfs:label "podocyte differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (head kidney development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") Annotation( "ZFA:0000669") "The process whose specific outcome is the progression of the head kidney over time, from its formation to the mature structure. The head kidney is a pronephros that consists of fused bilateral lobes located in the anterior part of the kidney. It is analogous to the mammalian bone marrow and the primary site of definitive hematopoiesis.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-02-22T11:09:38Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072113") -AnnotationAssertion(rdfs:label "head kidney development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (pronephros morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the anatomical structures of the pronephros are generated and organized. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-02-22T11:12:15Z") -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "pronephric kidney morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072114") -AnnotationAssertion(rdfs:label "pronephros morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (head kidney morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") Annotation( "ZFA:0000669") "The process in which the anatomical structures of the head kidney are generated and organized. The head kidney is a pronephros that consists of fused bilateral lobes located in the anterior part of the kidney.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-02-22T11:13:37Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072115") -AnnotationAssertion(rdfs:label "head kidney morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (pronephros formation) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The developmental process pertaining to the initial formation of the pronephros. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-02-22T11:16:26Z") -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "pronephric kidney formation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072116") -AnnotationAssertion(rdfs:label "pronephros formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (head kidney formation) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") Annotation( "ZFA:0000669") "The developmental process pertaining to the initial formation of the head kidney. The head kidney is a pronephros that consists of fused bilateral lobes located in the anterior part of the kidney.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-02-22T11:17:20Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072117") -AnnotationAssertion(rdfs:label "head kidney formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (pronephros maturation) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "A developmental process, independent of morphogenetic (shape) change, that is required for the pronephros to attain its fully functional state. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-02-22T11:25:48Z") -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "pronephric kidney maturation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072120") -AnnotationAssertion(rdfs:label "pronephros maturation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (head kidney maturation) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") Annotation( "ZFA:0000669") "A developmental process, independent of morphogenetic (shape) change, that is required for the head kidney to attain its fully functional state. The head kidney is a pronephros that consists of fused bilateral lobes located in the anterior part of the kidney.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-02-22T11:28:08Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072121") -AnnotationAssertion(rdfs:label "head kidney maturation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (renal capsule development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the renal capsule over time, from its formation to the mature structure. The renal capsule is the tough fibrous layer surrounding the kidney, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. During development, it comprises a single layer of flattened cells that lie just above the cortical stroma and the condensed mesenchyme of the nephrogenic zone. It is in this region that the early stages of nephron induction and formation of new generations ureteric bud branches occur, as the kidney expands.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-02-22T02:02:55Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072127") -AnnotationAssertion(rdfs:label "renal capsule development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (renal capsule morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the anatomical structures of the renal capsule are generated and organized. The renal capsule is the tough fibrous layer surrounding the kidney, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. During development, it comprises a single layer of flattened cells that lie just above the cortical stroma and the condensed mesenchyme of the nephrogenic zone. It is in this region that the early stages of nephron induction and formation of new generations ureteric bud branches occur, as the kidney expands.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-02-22T02:06:19Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072128") -AnnotationAssertion(rdfs:label "renal capsule morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (renal capsule formation) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The developmental process pertaining to the initial formation of a renal capsule from unspecified parts. The renal capsule is the tough fibrous layer surrounding the kidney, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. During development, it comprises a single layer of flattened cells that lie just above the cortical stroma and the condensed mesenchyme of the nephrogenic zone. It is in this region that the early stages of nephron induction and formation of new generations ureteric bud branches occur, as the kidney expands.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-02-22T02:08:14Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072129") -AnnotationAssertion(rdfs:label "renal capsule formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (kidney mesenchyme morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the anatomical structures of a kidney mesenchymal tissue are generated and organized. Kidney mesenchyme is the tissue made up of loosely connected mesenchymal cells in the kidney.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-02-22T02:16:43Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072131") -AnnotationAssertion(rdfs:label "kidney mesenchyme morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (mesenchyme morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the anatomical structures of a mesenchymal tissue are generated and organized. A mesenchymal tissue is made up of loosely packed stellate cells.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-02-22T02:17:15Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072132") -AnnotationAssertion(rdfs:label "mesenchyme morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (metanephric mesenchyme morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the anatomical structures of a metanephric mesenchymal tissue are generated and organized. Metanephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the metanephros.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-02-22T02:20:14Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072133") -AnnotationAssertion(rdfs:label "metanephric mesenchyme morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (nephrogenic mesenchyme morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the anatomical structures of a nephrogenic mesenchymal tissue are generated and organized. Nephrogenic mesenchyme is the tissue made up of loosely connected mesenchymal cells in the nephron.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-02-22T02:21:16Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072134") -AnnotationAssertion(rdfs:label "nephrogenic mesenchyme morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (mesenchymal cell proliferation involved in ureteric bud development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population of the ureteric bud, that contributes to ureteric bud development.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-02-22T02:40:38Z") -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "ureteric bud mesenchymal cell proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072138") -AnnotationAssertion(rdfs:label "mesenchymal cell proliferation involved in ureteric bud development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (glomerular parietal epithelial cell differentiation) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which a relatively unspecialized cell acquires specialized features of a glomerular parietal epithelial cell. Glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-02-24T01:33:05Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072139") -AnnotationAssertion(rdfs:label "glomerular parietal epithelial cell differentiation") -SubClassOf( ) - -# Class: (renal interstitial fibroblast development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of a renal interstitial fibroblast over time, from its formation to the mature structure.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-02-24T01:39:05Z") -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "kidney interstitial cell development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072141") -AnnotationAssertion(rdfs:label "renal interstitial fibroblast development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (juxtaglomerulus cell development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of a juxtaglomerulus cell over time, from its formation to the mature structure.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-02-24T01:42:53Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072142") -AnnotationAssertion(rdfs:label "juxtaglomerulus cell development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (mesangial cell development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of a mesangial cell in the kidney over time, from its formation to the mature structure.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-02-24T01:44:28Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072143") -AnnotationAssertion(rdfs:label "mesangial cell development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (epithelial cell migration involved in nephron tubule morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The orderly movement of epithelial cells within a renal tubule that contributes to nephron tubule morphogenesis.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-02-24T02:21:25Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072155") -AnnotationAssertion(rdfs:label "epithelial cell migration involved in nephron tubule morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (distal tubule morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the anatomical structures of a distal tubule are generated and organized. The distal tubule is a nephron tubule that begins at the macula densa and extends to the connecting tubule.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-02-24T02:32:03Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072156") -AnnotationAssertion(rdfs:label "distal tubule morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (epithelial cell migration involved in distal tubule morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The orderly movement of epithelial cells within a renal tubule that contributes to distal tubule morphogenesis.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-02-24T02:33:33Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072157") -AnnotationAssertion(rdfs:label "epithelial cell migration involved in distal tubule morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (proximal tubule morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the anatomical structures of a proximal tubule are generated and organized. The proximal tubule is a nephron tubule that connects Bowman's capsule to the descending thin limb of the loop of Henle. It has a brush border epithelial morphology.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-02-24T02:35:36Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072158") -AnnotationAssertion(rdfs:label "proximal tubule morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (epithelial cell migration involved in proximal tubule morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The orderly movement of epithelial cells within a renal tubule that contributes to proximal tubule morphogenesis.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-02-24T02:37:08Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072159") -AnnotationAssertion(rdfs:label "epithelial cell migration involved in proximal tubule morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (nephron tubule epithelial cell differentiation) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the nephron tubule as it progresses from its formation to the mature state.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-02-24T02:40:11Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072160") -AnnotationAssertion(rdfs:label "nephron tubule epithelial cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (mesenchymal cell differentiation involved in kidney development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of the kidney as it progresses from its formation to the mature state.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-02-26T01:31:49Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072161") -AnnotationAssertion(rdfs:label "mesenchymal cell differentiation involved in kidney development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (mesonephric epithelium development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of an epithelium in the mesonephros over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-02-26T01:40:43Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072163") -AnnotationAssertion(rdfs:label "mesonephric epithelium development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (mesonephric tubule development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The progression of a mesonephric tubule over time, from its initial formation to the mature structure. A mesonephric tubule is an epithelial tube that is part of the mesonephros.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-02-26T01:45:58Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072164") -AnnotationAssertion(rdfs:label "mesonephric tubule development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (anterior mesonephric tubule development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The progression of the anterior mesonephric tubule over time, from its initial formation to the mature structure. The anterior mesonephric tubule is an epithelial tube that is part of the mesonephros.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-02-26T01:47:26Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072165") -AnnotationAssertion(rdfs:label "anterior mesonephric tubule development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (posterior mesonephric tubule development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The progression of the posterior mesonephric tubule over time, from its initial formation to the mature structure. The posterior mesonephric tubule is an epithelial tube that is part of the mesonephros.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-02-26T01:47:50Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072166") -AnnotationAssertion(rdfs:label "posterior mesonephric tubule development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (metanephric tubule development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The progression of a metanephric tubule over time, from its initial formation to the mature structure. A metanephric tubule is an epithelial tube that is part of the metanephros.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-02-26T01:58:18Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072170") -AnnotationAssertion(rdfs:label "metanephric tubule development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (mesonephric tubule morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the anatomical structures of a mesonephric tubule are generated and organized. A mesonephric tubule is an epithelial tube that is part of the mesonephros.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-02-26T02:02:13Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072171") -AnnotationAssertion(rdfs:label "mesonephric tubule morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (mesonephric tubule formation) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The developmental process pertaining to the initial formation of a mesonephric tubule from unspecified parts. A mesonephric tubule is an epithelial tube that is part of the mesonephros.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-02-26T02:02:37Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072172") -AnnotationAssertion(rdfs:label "mesonephric tubule formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (metanephric tubule morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the anatomical structures of a metanephric tubule are generated and organized from an epithelium. A metanephric tubule is an epithelial tube that is part of the metanephros.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-02-26T02:06:42Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072173") -AnnotationAssertion(rdfs:label "metanephric tubule morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (metanephric tubule formation) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The developmental process pertaining to the initial formation of a metanephric tubule.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-02-26T02:07:41Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072174") -AnnotationAssertion(rdfs:label "metanephric tubule formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (epithelial tube formation) AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The developmental process pertaining to the initial formation of an epithelial tube.") @@ -107899,1186 +27442,8 @@ AnnotationAssertion( AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0072175") AnnotationAssertion(rdfs:label "epithelial tube formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (nephric duct development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of a nephric duct over time, from its initial formation to a mature structure. A nephric duct is a tube that drains a primitive kidney.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-02-26T02:27:31Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072176") -AnnotationAssertion(rdfs:label "nephric duct development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (mesonephric duct development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of a mesonephric duct over time, from its initial formation to a mature structure. A mesonephric duct is a tube drains the mesonephros.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-02-26T02:32:22Z") -AnnotationAssertion(Annotation( "GOC:dph") "Wolffian duct development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072177") -AnnotationAssertion(rdfs:label "mesonephric duct development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (nephric duct morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the anatomical structures of the nephric duct are generated and organized. A nephric duct is a tube that drains a primitive kidney.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-02-26T02:35:29Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072178") -AnnotationAssertion(rdfs:label "nephric duct morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (nephric duct formation) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The developmental process pertaining to the initial formation of a nephric duct. A nephric duct is a tube that drains a primitive kidney.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-02-26T02:35:55Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072179") -AnnotationAssertion(rdfs:label "nephric duct formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (mesonephric duct morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the anatomical structures of the mesonephric duct are generated and organized. A mesonephric duct is a tube drains the mesonephros.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-02-26T02:37:13Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") "Wolffian duct morphogenesis") -AnnotationAssertion( "GO:0072180") -AnnotationAssertion(rdfs:label "mesonephric duct morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (mesonephric duct formation) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The developmental process pertaining to the initial formation of a mesonephric duct. A mesonephric duct is a tube that drains the mesonephros.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-02-26T02:38:03Z") -AnnotationAssertion(Annotation( "GOC:dph") "Wolffian duct formation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072181") -AnnotationAssertion(rdfs:label "mesonephric duct formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of nephron tubule epithelial cell differentiation) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "Any process that modulates the frequency, rate or extent of nephron tubule epithelial cell differentiation.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-02-26T02:45:09Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072182") -AnnotationAssertion(rdfs:label "regulation of nephron tubule epithelial cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of nephron tubule epithelial cell differentiation) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "Any process that decreases the frequency, rate or extent of nephron tubule epithelial cell differentiation.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-02-26T02:47:25Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072183") -AnnotationAssertion(rdfs:label "negative regulation of nephron tubule epithelial cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (metanephric cap development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The biological process whose specific outcome is the progression of the metanephric cap from an initial condition to its mature state. The metanephric cap is formed by the condensation of metanephric mesenchymal cells surrounding the ureteric bud tip.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-03-01T01:20:22Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072185") -AnnotationAssertion(rdfs:label "metanephric cap development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (metanephric cap morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the anatomical structures of the metanephric cap are generated and organized. The metanephric cap is formed by the condensation of metanephric mesenchymal cells surrounding the ureteric bud tip.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-03-01T01:22:51Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072186") -AnnotationAssertion(rdfs:label "metanephric cap morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (metanephric cap formation) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The developmental process pertaining to the initial formation of a metanephric cap from unspecified parts. The metanephric cap is formed by the condensation of metanephric mesenchymal cells surrounding the ureteric bud tip.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-03-01T01:26:53Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072187") -AnnotationAssertion(rdfs:label "metanephric cap formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (ureter development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the ureter over time, from its formation to the mature structure. The ureter is a muscular tube that transports urine from the kidney to the urinary bladder or from the Malpighian tubule to the hindgut.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-03-01T01:44:14Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072189") -AnnotationAssertion(rdfs:label "ureter development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (ureter urothelium development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the urothelium of the ureter over time, from its formation to the mature structure. The urothelium is an epithelium that makes up the epithelial tube of the ureter.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-03-01T01:46:31Z") -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "ureter epithelium development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072190") -AnnotationAssertion(rdfs:label "ureter urothelium development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (ureter smooth muscle development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of smooth muscle in the ureter over time, from its formation to the mature structure.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-03-01T01:48:53Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072191") -AnnotationAssertion(rdfs:label "ureter smooth muscle development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (ureter smooth muscle cell differentiation) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell in the ureter.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-03-01T01:55:01Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072193") -AnnotationAssertion(rdfs:label "ureter smooth muscle cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (kidney smooth muscle tissue development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of smooth muscle in the kidney over time, from its formation to the mature structure.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-03-01T02:05:30Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072194") -AnnotationAssertion(rdfs:label "kidney smooth muscle tissue development") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (ureter morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the anatomical structures of the ureter are generated and organized. The ureter is a muscular tube that transports urine from the kidney to the urinary bladder.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-03-01T02:24:55Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072197") -AnnotationAssertion(rdfs:label "ureter morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (mesenchymal cell proliferation involved in ureter development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population of the ureter, that contributes to ureter development.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-03-01T03:24:41Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "ureter mesenchymal cell proliferation") -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "ureteral mesenchymal cell proliferation") -AnnotationAssertion( "GO:0072198") -AnnotationAssertion(rdfs:label "mesenchymal cell proliferation involved in ureter development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of mesenchymal cell proliferation involved in ureter development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "Any process that modulates the frequency, rate or extent of mesenchymal cell proliferation that contributes to the progression of the ureter gland over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-03-01T03:38:13Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "regulation of ureter mesenchymal cell proliferation") -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "regulation of ureteral mesenchymal cell proliferation") -AnnotationAssertion( "GO:0072199") -AnnotationAssertion(rdfs:label "regulation of mesenchymal cell proliferation involved in ureter development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of mesenchymal cell proliferation involved in ureter development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "Any process that decreases the frequency, rate or extent of mesenchymal cell proliferation that contributes to the progression of the ureter gland over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-03-01T03:42:31Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "negative regulation of ureter mesenchymal cell proliferation") -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "negative regulation of ureteral mesenchymal cell proliferation") -AnnotationAssertion( "GO:0072200") -AnnotationAssertion(rdfs:label "negative regulation of mesenchymal cell proliferation involved in ureter development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (negative regulation of mesenchymal cell proliferation) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "Any process that decreases the frequency, rate or extent of mesenchymal cell proliferation. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-03-01T03:43:29Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072201") -AnnotationAssertion(rdfs:label "negative regulation of mesenchymal cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (cell differentiation involved in metanephros development) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:mtg_kidney_jan10") "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the metanephros as it progresses from its formation to the mature state.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-03-18T10:40:14Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072202") -AnnotationAssertion(rdfs:label "cell differentiation involved in metanephros development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cell proliferation involved in metanephros development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The multiplication or reproduction of cells, resulting in the expansion of the population in the metanephros.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-03-18T10:42:27Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072203") -AnnotationAssertion(rdfs:label "cell proliferation involved in metanephros development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cell-cell signaling involved in metanephros development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "Any process that mediates the transfer of information from one cell to another and contributes to the progression of the metanephros over time, from its formation to the mature organ.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-03-18T10:54:36Z") -AnnotationAssertion(Annotation( "GOC:mah") "cell-cell signalling involved in metanephros development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072204") -AnnotationAssertion(rdfs:label "cell-cell signaling involved in metanephros development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (metanephric collecting duct development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of a collecting duct in the metanephros over time, from its formation to the mature structure. The collecting duct responds to vasopressin and aldosterone to regulate water, electrolyte and acid-base balance. The collecting duct is the final common path through which urine flows before entering the ureter and then emptying into the bladder.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-03-18T11:15:37Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072205") -AnnotationAssertion(rdfs:label "metanephric collecting duct development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (metanephric juxtaglomerular apparatus development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the juxtaglomerular apparatus in the metanephros over time, from its formation to the mature structure. The juxtaglomerular apparatus is an anatomical structure which consists of juxtaglomerular cells, extraglomerular mesangial cells and the macula densa. The juxtaglomerular apparatus lies adjacent to the glomerulus and regulates kidney function by maintaining the blood flow to the kidney and the filtration rate.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-03-18T11:17:47Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072206") -AnnotationAssertion(rdfs:label "metanephric juxtaglomerular apparatus development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (metanephric epithelium development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of an epithelium in the metanephros over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-03-18T11:50:37Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072207") -AnnotationAssertion(rdfs:label "metanephric epithelium development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (metanephric smooth muscle tissue development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of smooth muscle in the metanephros over time, from its formation to the mature structure.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-03-18T11:51:59Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072208") -AnnotationAssertion(rdfs:label "metanephric smooth muscle tissue development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (metanephric nephron development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of a nephron in the metanephros over time, from its formation to the mature structure. A nephron is the functional unit of the kidney.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-03-18T12:52:57Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072210") -AnnotationAssertion(rdfs:label "metanephric nephron development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (metanephric pyramids development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the metanephric pyramids over time, from their formation to the mature structures. Metanephric pyramids are the conical masses that constitute the renal medulla in a metanephros; they contain the loops of Henle and the medullary collecting ducts.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-03-18T01:04:51Z") -AnnotationAssertion(Annotation( "GOC:mah") "metanephric kidney pyramid development") -AnnotationAssertion(Annotation( "GOC:mah") "metanephric pyramid development") -AnnotationAssertion(Annotation( "GOC:mah") "metanephric renal medulla development") -AnnotationAssertion(Annotation( "GOC:mah") "metanephric renal pyramid development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072211") -AnnotationAssertion(rdfs:label "metanephric pyramids development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (metanephric capsule development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the metanephric capsule over time, from its formation to the mature structure. The metanephric capsule is the tough fibrous layer surrounding the metanephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-03-18T01:25:19Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072213") -AnnotationAssertion(rdfs:label "metanephric capsule development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (metanephric cortex development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the metanephric cortex over time, from its formation to the mature structure. The metanephric cortex is the outer region of the metanephros.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-03-18T01:29:49Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072214") -AnnotationAssertion(rdfs:label "metanephric cortex development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (regulation of metanephros development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "Any process that modulates the rate, frequency or extent of metanephros development. Metanephros development is the process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. The metanephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072215") -AnnotationAssertion(rdfs:label "regulation of metanephros development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of metanephros development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "Any process that increases the rate, frequency or extent of metanephros development. Metanephros development is the process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. The metanephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-03-18T01:40:12Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072216") -AnnotationAssertion(rdfs:label "positive regulation of metanephros development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of metanephros development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "Any process that decreases the rate, frequency or extent of metanephros development. Metanephros development is the process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. The metanephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-03-18T01:45:48Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072217") -AnnotationAssertion(rdfs:label "negative regulation of metanephros development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (metanephric ascending thin limb development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of a metanephric ascending thin limb over time, from its formation to the mature structure. The metanephric ascending thin limb is a segment of a nephron tubule in the metanephros lying in the inner medulla that is permeable to ions but not to water and has a simple epithelium; active transepithelial solute transport is absent.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-03-18T03:34:42Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072218") -AnnotationAssertion(rdfs:label "metanephric ascending thin limb development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (metanephric cortical collecting duct development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the metanephric cortical collecting duct over time, from its formation to the mature structure. The metanephric cortical collecting duct is the portion of the metanephric collecting duct that resides in the renal cortex.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-03-18T03:34:52Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072219") -AnnotationAssertion(rdfs:label "metanephric cortical collecting duct development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (metanephric descending thin limb development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the metanephric descending thin limb over time, from its formation to the mature structure. The metanephric descending thin limb is a part of the metanephric loop of Henle situated just after the proximal straight tubule (S3). It extends to the tip of the metanephric loop of Henle.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-03-18T03:35:05Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072220") -AnnotationAssertion(rdfs:label "metanephric descending thin limb development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (metanephric distal convoluted tubule development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the metanephric distal convoluted tubule over time, from its formation to the mature structure. The metanephric distal convoluted tubule is the first segment of the metanephric nephron lying just downstream from the loop of Henle, immediately after the macula densa. Among other functions, in humans it is responsible for the reabsorption of about 5% of filtered sodium via the thiazide-sensitive Na-Cl symporter.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-03-18T03:35:27Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072221") -AnnotationAssertion(rdfs:label "metanephric distal convoluted tubule development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (metanephric early distal convoluted tubule development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the metanephric early distal convoluted tubule over time, from its formation to the mature structure. The metanephric early distal convoluted tubule contains metanephric DCT cells and is vasopressin-insensitive.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-03-18T03:35:46Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072222") -AnnotationAssertion(rdfs:label "metanephric early distal convoluted tubule development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (metanephric glomerular mesangium development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the metanephric glomerular mesangium over time, from its formation to the mature structure. The metanephric glomerular mesangium is the thin membrane connective tissue composed of mesangial cells in the metanephros, which helps to support the capillary loops in a renal glomerulus.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-03-18T03:35:56Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072223") -AnnotationAssertion(rdfs:label "metanephric glomerular mesangium development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (metanephric glomerulus development) - -AnnotationAssertion(Annotation( "GOC:mah") "The progression of the metanephric glomerulus over time from its initial formation until its mature state. The metanephric glomerulus is a capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the mature vertebrate kidney, or metanephros.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-03-18T03:36:20Z") -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "metanephric glomerular development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072224") -AnnotationAssertion(rdfs:label "metanephric glomerulus development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (metanephric late distal convoluted tubule development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the metanephric late distal convoluted tubule over time, from its formation to the mature structure. The metanephric late distal convoluted tubule contains metanephric DCT cells and intercalated (IC) alpha and beta cells and is vasopressin-sensitive.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-03-18T03:37:04Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072225") -AnnotationAssertion(rdfs:label "metanephric late distal convoluted tubule development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (metanephric long descending thin limb bend development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the metanephric long descending thin limb bend over time, from its formation to the mature structure. The metanephric long descending thin limb bend is a part of the descending thin limb of a long nephron that lies beyond the prebend segment in the metanephros.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-03-18T03:37:16Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072226") -AnnotationAssertion(rdfs:label "metanephric long descending thin limb bend development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (metanephric macula densa development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the metanephric macula densa over time, from its formation to the mature structure. The metanephric macula densa is an area of specialized cells in the distal tubule of the metanephros that makes contact with the vascular pole of the glomerulus.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-03-18T03:37:26Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072227") -AnnotationAssertion(rdfs:label "metanephric macula densa development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (metanephric prebend segment development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the metanephric prebend segment over time, from its formation to the mature structure. The metanephric prebend segment is a part of the metanephric descending thin limb that lies before the bend and exhibits permeabilities characteristic of the ascending limb, especially negligible water permeability.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-03-18T03:37:46Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072228") -AnnotationAssertion(rdfs:label "metanephric prebend segment development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (metanephric proximal convoluted tubule development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the metanephric proximal convoluted tubule over time, from its formation to the mature structure. The metanephric proximal convoluted tubule is the most proximal portion of the metanephric proximal tubule and extends from the metanephric glomerular capsule to the metanephric proximal straight tubule.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-03-18T03:37:56Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072229") -AnnotationAssertion(rdfs:label "metanephric proximal convoluted tubule development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (metanephric proximal straight tubule development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the metanephric proximal straight tubule over time, from its formation to the mature structure. The metanephric proximal straight tubule is the part of the metanephric descending limb that extends from the metanephric proximal convoluted tubule to the metanephric descending thin tubule.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-03-18T03:38:53Z") -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "metanephric S3 development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072230") -AnnotationAssertion(rdfs:label "metanephric proximal straight tubule development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (metanephric proximal convoluted tubule segment 1 development) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the S1 portion of the metanephric proximal convoluted tubule over time, from its formation to the mature structure. The S1 portion is the initial portion of the metanephric proximal convoluted tubule and is responsible for avid reabsorption of water and solutes.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-03-18T03:39:10Z") -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "metanephric S1 development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072231") -AnnotationAssertion(rdfs:label "metanephric proximal convoluted tubule segment 1 development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (metanephric thick ascending limb development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the metanephric thick ascending limb over time, from its formation to the mature structure. The metanephric thick ascending limb is the last part of the metanephric loop of Henle. Its thick, mitochondria-rich epithelium characterizes the outer medulla, and is responsible for very avid active salt transport. At the macula densa, the thick ascending limb connects to the distal convoluted tubule.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-03-18T03:39:36Z") -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "metanephric TAL development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072233") -AnnotationAssertion(rdfs:label "metanephric thick ascending limb development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (metanephric nephron tubule development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The progression of a metanephric nephron tubule over time, from its initial formation to the mature structure. A metanephric nephron tubule is an epithelial tube that is part of the metanephric nephron, the functional part of the metanephros.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-03-18T03:41:23Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072234") -AnnotationAssertion(rdfs:label "metanephric nephron tubule development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (metanephric distal tubule development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the metanephric distal tubule over time, from its formation to the mature structure. The metanephric distal tubule is a metanephric nephron tubule that begins at the metanephric macula densa and extends to the metanephric connecting tubule.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-03-18T03:45:37Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072235") -AnnotationAssertion(rdfs:label "metanephric distal tubule development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (metanephric loop of Henle development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the metanephric loop of Henle over time, from its formation to the mature structure. The metanephric loop of Henle is a metanephric nephron tubule that connects the proximal convoluted tubule to the distal convoluted tubule in the metanephros.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-03-18T03:46:18Z") -AnnotationAssertion( "metanephric intermediate tubule development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072236") -AnnotationAssertion(rdfs:label "metanephric loop of Henle development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (metanephric proximal tubule development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the metanephric proximal tubule over time, from its formation to the mature structure. The metanephric proximal tubule is a metanephric nephron tubule that connects Bowman's capsule to the descending thin limb of the loop of Henle in the metanephros. It has a brush border epithelial morphology.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-03-18T03:46:54Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072237") -AnnotationAssertion(rdfs:label "metanephric proximal tubule development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (metanephric long nephron development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of a metanephric long nephron over time, from its formation to the mature structure. Long nephrons are associated with juxtamedullary glomeruli and extend into the inner medulla in the metanephros.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-03-18T03:48:23Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "metanephric juxtamedullary nephron development") -AnnotationAssertion( "GO:0072238") -AnnotationAssertion(rdfs:label "metanephric long nephron development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (metanephric glomerulus vasculature development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The biological process whose specific outcome is the progression of a metanephric glomerulus vasculature from an initial condition to its mature state. This process begins with the formation of the metanephric glomerulus vasculature and ends with the mature structure. The metanephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the metanephric glomerulus.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-03-18T03:50:29Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "glomerulus capillary development") -AnnotationAssertion( "GO:0072239") -AnnotationAssertion(rdfs:label "metanephric glomerulus vasculature development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (metanephric nephron epithelium development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the metanephric nephron epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The metanephric nephron epithelium is a tissue that covers the surface of a nephron in the metanephros.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-03-19T03:29:49Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072243") -AnnotationAssertion(rdfs:label "metanephric nephron epithelium development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (metanephric glomerular epithelium development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the metanephric glomerular epithelium over time, from its formation to the mature structure. The metanephric glomerular epithelium is an epithelial tissue that covers the outer surfaces of the glomerulus in the metanephros. The metanephric glomerular epithelium consists of both parietal and visceral epithelium. Metanephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the metanephros.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-03-19T03:38:47Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072244") -AnnotationAssertion(rdfs:label "metanephric glomerular epithelium development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (metanephric podocyte differentiation) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which a relatively unspecialized cell acquires specialized features of a metanephric glomerular visceral epithelial cell. A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the metanephros.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/23000"^^xsd:anyURI) -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-03-19T03:44:57Z") -AnnotationAssertion( "metanephric glomerular visceral epithelial cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072248") -AnnotationAssertion(rdfs:label "metanephric podocyte differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (metanephric podocyte development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of a metanephric glomerular visceral epithelial cell over time, from its formation to the mature structure. A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the metanephros.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/23000"^^xsd:anyURI) -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-03-19T03:46:26Z") -AnnotationAssertion( "metanephric glomerular visceral epithelial cell development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072249") -AnnotationAssertion(rdfs:label "metanephric podocyte development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (metanephric nephron tubule epithelial cell differentiation) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the metanephric nephron tubule as it progresses from its formation to the mature state.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-03-19T04:11:02Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072257") -AnnotationAssertion(rdfs:label "metanephric nephron tubule epithelial cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (metanephric glomerular endothelium development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the metanephric glomerular endothelium over time, from its formation to the mature structure. The metanephric glomerular endothelium is an epithelial tissue that covers the internal surfaces of the glomerulus of the metanephros.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-03-30T02:42:26Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072264") -AnnotationAssertion(rdfs:label "metanephric glomerular endothelium development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (metanephric capsule morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the anatomical structures of the metanephric capsule are generated and organized. The metanephric capsule is the tough fibrous layer surrounding the metanephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-03-30T02:54:49Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072265") -AnnotationAssertion(rdfs:label "metanephric capsule morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (metanephric capsule formation) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The developmental process pertaining to the initial formation of a metanephric capsule from unspecified parts. The metanephric capsule is the tough fibrous layer surrounding the metanephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-03-30T02:56:35Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072266") -AnnotationAssertion(rdfs:label "metanephric capsule formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (pattern specification involved in metanephros development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "Any developmental process that results in the creation of defined areas or spaces within the metanephros to which cells respond and eventually are instructed to differentiate.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-03-30T03:06:30Z") -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "metanephros pattern specification") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "metanephros pattern formation") -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "pattern formation involved in metanephros development") -AnnotationAssertion( "GO:0072268") -AnnotationAssertion(rdfs:label "pattern specification involved in metanephros development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (metanephric long descending thin limb development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the metanephric long descending thin limb over time, from its formation to the mature structure. The metanephric long descending thin limb is the descending thin limb of a long nephron in the metanephros that has a squamous epithelial morphology. The long descending limb starts in the inner stripe of the outer medulla and extends into the inner medulla.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-03-30T03:12:05Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072269") -AnnotationAssertion(rdfs:label "metanephric long descending thin limb development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (metanephric short nephron development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of a short nephron in the metanephros over time, from its formation to the mature structure. Short nephrons are associated with mid-cortical and superficial glomeruli, are situated entirely in the outer medulla, and have no thin ascending limb.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-03-30T03:15:18Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072270") -AnnotationAssertion(rdfs:label "metanephric short nephron development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (metanephric short descending thin limb development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the metanephric short descending thin limb over time, from its formation to the mature structure. The metanephric short descending thin limb is the descending thin limb of a short nephron in the metanephros that has a squamous epithelial morphology.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-03-30T03:16:25Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072271") -AnnotationAssertion(rdfs:label "metanephric short descending thin limb development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (metanephric nephron morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the anatomical structures of the metanephric nephron are generated and organized. A metanephric nephron is the functional unit of the metanephros.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-03-30T03:33:19Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072273") -AnnotationAssertion(rdfs:label "metanephric nephron morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (metanephric glomerulus morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the anatomical structures of the metanephric glomerulus are generated and organized. The metanephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney, or metanephros.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-04-01T02:46:58Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072275") -AnnotationAssertion(rdfs:label "metanephric glomerulus morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (metanephric glomerulus vasculature morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the anatomical structures of the metanephric glomerulus vasculature are generated and organized. The metanephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the metanephric glomerulus.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-04-01T02:47:32Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072276") -AnnotationAssertion(rdfs:label "metanephric glomerulus vasculature morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (metanephric glomerular capillary formation) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process that gives rise to a metanephric glomerular capillary. This process pertains to the initial formation of a structure from unspecified parts.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-04-01T02:47:56Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072277") -AnnotationAssertion(rdfs:label "metanephric glomerular capillary formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (metanephric comma-shaped body morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the metanephric comma-shaped body is generated and organized. The metanephric comma-shaped body is the precursor structure to the metanephric S-shaped body that contributes to the morphogenesis of a nephron in the metanephros.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-04-01T03:14:42Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072278") -AnnotationAssertion(rdfs:label "metanephric comma-shaped body morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (metanephric nephron tubule morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the anatomical structures of a metanephric nephron tubule are generated and organized. A metanephric nephron tubule is an epithelial tube that is part of the metanephric nephron, the functional part of the metanephros.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-04-01T03:25:11Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072282") -AnnotationAssertion(rdfs:label "metanephric nephron tubule morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (metanephric renal vesicle morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the anatomical structures of the metanephric renal vesicle are generated and organized. The renal vesicle is the primordial structure of the metanephric nephron epithelium, and is formed by the condensation of mesenchymal cells.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-04-01T03:28:00Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072283") -AnnotationAssertion(rdfs:label "metanephric renal vesicle morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (metanephric S-shaped body morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the metanephric S-shaped body is generated and organized. The metanephric S-shaped body is the successor of the metanephric comma-shaped body that contributes to the morphogenesis of a nephron in the metanephros.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-04-01T03:41:36Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072284") -AnnotationAssertion(rdfs:label "metanephric S-shaped body morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (mesenchymal to epithelial transition involved in metanephric renal vesicle formation) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephric renal vesicle.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-04-01T03:43:31Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072285") -AnnotationAssertion(rdfs:label "mesenchymal to epithelial transition involved in metanephric renal vesicle formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (metanephric connecting tubule development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the metanephric connecting tubule over time, from its formation to the mature structure. The metanephric connecting tubule is a tubular segment of the metanephric nephron; it connects the distal convoluted tubule to the collecting duct in the metanephros.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-04-09T03:30:09Z") -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "metanephric connecting duct development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072286") -AnnotationAssertion(rdfs:label "metanephric connecting tubule development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (metanephric distal tubule morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the anatomical structures of a metanephric distal tubule are generated and organized. The metanephric distal tubule is a metanephric nephron tubule that begins at the macula densa and extends to the metanephric connecting tubule.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-04-09T03:41:47Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072287") -AnnotationAssertion(rdfs:label "metanephric distal tubule morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (metanephric proximal tubule morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the anatomical structures of a metanephric proximal tubule are generated and organized. The metanephric proximal tubule is a metanephric nephron tubule that connects Bowman's capsule to the descending thin limb of the loop of Henle in the metanephros. It has a brush border epithelial morphology.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-04-09T03:42:03Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072288") -AnnotationAssertion(rdfs:label "metanephric proximal tubule morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (metanephric nephron tubule formation) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The developmental process pertaining to the initial formation of a metanephric nephron tubule from unspecified parts. A metanephric nephron tubule is an epithelial tube that is part of a nephron in the metanephros.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-04-09T03:47:44Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072289") -AnnotationAssertion(rdfs:label "metanephric nephron tubule formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (epithelial cell migration involved in metanephric nephron tubule morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The orderly movement of epithelial cells within a renal tubule that contributes to metanephric nephron tubule morphogenesis.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-04-09T03:52:29Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072290") -AnnotationAssertion(rdfs:label "epithelial cell migration involved in metanephric nephron tubule morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (epithelial cell migration involved in metanephric distal tubule morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The orderly movement of epithelial cells within a renal tubule that contributes to metanephric distal tubule morphogenesis.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-04-09T03:53:37Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072291") -AnnotationAssertion(rdfs:label "epithelial cell migration involved in metanephric distal tubule morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (epithelial cell migration involved in metanephric proximal tubule morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The orderly movement of epithelial cells within a renal tubule that contributes to metanephric proximal tubule morphogenesis.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-04-09T03:54:28Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072292") -AnnotationAssertion(rdfs:label "epithelial cell migration involved in metanephric proximal tubule morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of metanephric glomerulus development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "Any process that modulates the rate, frequency or extent of metanephric glomerulus development, the progression of the metanephric glomerulus over time from its initial formation until its mature state. The metanephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney, or metanephros.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-04-09T05:03:14Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072298") -AnnotationAssertion(rdfs:label "regulation of metanephric glomerulus development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (negative regulation of metanephric glomerulus development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "Any process that decreases the rate, frequency or extent of metanephric glomerulus development, the progression of the metanephric glomerulus over time from its initial formation until its mature state. The metanephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney, or metanephros.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-04-09T05:03:41Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072299") -AnnotationAssertion(rdfs:label "negative regulation of metanephric glomerulus development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (positive regulation of metanephric glomerulus development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "Any process that increases the rate, frequency or extent of metanephric glomerulus development, the progression of the metanephric glomerulus over time from its initial formation until its mature state. The metanephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney, or metanephros.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-04-09T05:03:41Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072300") -AnnotationAssertion(rdfs:label "positive regulation of metanephric glomerulus development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:mtg_kidney_jan10") "Any process that modulates the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the metanephros.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-04-09T05:03:41Z") -AnnotationAssertion( "regulation of mesenchymal stem cell apoptotic process involved in metanephric nephron morphogenesis") -AnnotationAssertion( "regulation of mesenchymal stem cell apoptosis involved in metanephric nephron morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072304") -AnnotationAssertion(rdfs:label "regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:mtg_kidney_jan10") "Any process that reduces the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the metanephros.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-04-09T05:03:41Z") -AnnotationAssertion( "negative regulation of mesenchymal stem cell apoptotic process involved in metanephric nephron morphogenesis") -AnnotationAssertion( "negative regulation of mesenchymal stem cell apoptosis involved in metanephric nephron morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072305") -AnnotationAssertion(rdfs:label "negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (positive regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:mtg_kidney_jan10") "Any process that increases the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the metanephros.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-04-09T05:03:41Z") -AnnotationAssertion( "positive regulation of mesenchymal stem cell apoptotic process involved in metanephric nephron morphogenesis") -AnnotationAssertion( "positive regulation of mesenchymal stem cell apoptosis involved in metanephric nephron morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072306") -AnnotationAssertion(rdfs:label "positive regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (regulation of metanephric nephron tubule epithelial cell differentiation) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "Any process that modulates the frequency, rate or extent of metanephric nephron tubule epithelial cell differentiation.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-04-09T05:03:41Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072307") -AnnotationAssertion(rdfs:label "regulation of metanephric nephron tubule epithelial cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of metanephric nephron tubule epithelial cell differentiation) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "Any process that decreases the frequency, rate or extent of metanephric nephron tubule epithelial cell differentiation.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-04-09T05:03:41Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072308") -AnnotationAssertion(rdfs:label "negative regulation of metanephric nephron tubule epithelial cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which an organism retains a population of mesenchymal stem cells that contributes to the shaping of a nephron in the metanephros. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-04-09T05:03:41Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072309") -AnnotationAssertion(rdfs:label "mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (glomerular epithelial cell development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of a glomerular epithelial cell over time, from its formation to the mature structure. Glomerular epithelial cells are specialized epithelial cells that form part of the glomerulus; there are two types, glomerular parietal epithelial cells and glomerular visceral epithelial cells.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-04-09T06:47:31Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072310") -AnnotationAssertion(rdfs:label "glomerular epithelial cell development") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (glomerular epithelial cell differentiation) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which a relatively unspecialized cell acquires specialized features of a glomerular epithelial cell. Glomerular epithelial cells are specialized epithelial cells that form part of the glomerulus; there are two types, glomerular parietal epithelial cells and glomerular visceral epithelial cells.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-04-09T06:49:21Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072311") -AnnotationAssertion(rdfs:label "glomerular epithelial cell differentiation") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (metanephric glomerular epithelial cell differentiation) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which a relatively unspecialized cell acquires specialized features of a metanephric glomerular epithelial cell. Metanephric glomerular epithelial cells are specialized epithelial cells that form part of the metanephric glomerulus; there are two types, metanephric glomerular parietal epithelial cells and metanephric glomerular visceral epithelial cells.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-04-09T06:54:15Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072312") -AnnotationAssertion(rdfs:label "metanephric glomerular epithelial cell differentiation") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (metanephric glomerular epithelial cell development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of a metanephric glomerular epithelial cell over time, from its formation to the mature structure. Metanephric glomerular epithelial cells are specialized epithelial cells that form part of the metanephric glomerulus; there are two types, metanephric glomerular parietal epithelial cells and metanephric glomerular visceral epithelial cells.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-04-09T06:57:26Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072313") -AnnotationAssertion(rdfs:label "metanephric glomerular epithelial cell development") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (monocarboxylic acid catabolic process) - -AnnotationAssertion(Annotation( "GOC:mah") "The chemical reactions and pathways resulting in the breakdown of monocarboxylic acids, any organic acid containing one carboxyl (-COOH) group.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-11-02T04:41:55Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072329") -AnnotationAssertion(rdfs:label "monocarboxylic acid catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (monocarboxylic acid biosynthetic process) AnnotationAssertion(Annotation( "GOC:mah") "The chemical reactions and pathways resulting in the formation of monocarboxylic acids, any organic acid containing one carboxyl (-COOH) group.") @@ -109091,439 +27456,9 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:0072330") AnnotationAssertion(rdfs:label "monocarboxylic acid biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) -# Class: (modified amino acid transport) - -AnnotationAssertion(Annotation( "GOC:mah") "The directed movement of modified amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-11-04T12:18:23Z") -AnnotationAssertion( "amino acid derivative transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072337") -AnnotationAssertion(rdfs:label "modified amino acid transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (modified amino acid binding) - -AnnotationAssertion(Annotation( "GOC:mah") "Binding to a modified amino acid.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-11-04T05:45:32Z") -AnnotationAssertion( "amino acid derivative binding") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0072341") -AnnotationAssertion(rdfs:label "modified amino acid binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (sulfur compound transport) - -AnnotationAssertion(Annotation( "GOC:mah") "The directed movement of compounds that contain sulfur, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-11-11T11:43:56Z") -AnnotationAssertion(Annotation( "GOC:mah") "sulfur-containing compound transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072348") -AnnotationAssertion(rdfs:label "sulfur compound transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (modified amino acid transmembrane transporter activity) - -AnnotationAssertion(Annotation( "GOC:mah") "Enables the transfer of modified amino acids from one side of a membrane to the other.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-11-11T11:50:31Z") -AnnotationAssertion(Annotation( "GOC:mah") "modified amino acid transporter activity") -AnnotationAssertion( "amino acid derivative transmembrane transporter activity") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0072349") -AnnotationAssertion(rdfs:label "modified amino acid transmembrane transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (circulatory system development) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "UBERON:0001009") "The process whose specific outcome is the progression of the circulatory system over time, from its formation to the mature structure. The circulatory system is the organ system that passes nutrients (such as amino acids and electrolytes), gases, hormones, blood cells, etc. to and from cells in the body to help fight diseases and help stabilize body temperature and pH to maintain homeostasis.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-11-16T11:27:39Z") -AnnotationAssertion( "GO:0072358") -AnnotationAssertion( "cardiovascular system development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072359") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "circulatory system development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (vascular cord development) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "PMID:7084422") Annotation( "ZFA:0005077") "The progression of the vascular cord over time from its initial formation until its mature state. The vascular cord is the primordial vasculature that will develop into blood vessels by the process of tubulogenesis.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-11-16T11:46:55Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072360") -AnnotationAssertion(rdfs:label "vascular cord development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (organelle transport along microtubule) - -AnnotationAssertion(Annotation( "GOC:mah") "The directed movement of an organelle along a microtubule, mediated by motor proteins. This process begins with the attachment of an organelle to a microtubule, and ends when the organelle reaches its final destination.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-12-01T04:59:11Z") -AnnotationAssertion(Annotation( "GOC:rl") "microtubule-based organelle localization") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072384") -AnnotationAssertion(rdfs:label "organelle transport along microtubule") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (ammonium transmembrane transport) - -AnnotationAssertion(Annotation( "GOC:mah") "The process in which ammonium is transported across a membrane. Ammonium is the cation NH4+.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/22228"^^xsd:anyURI) -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-12-10T10:29:57Z") -AnnotationAssertion( "GO:0015696") -AnnotationAssertion( "ammonia transport") -AnnotationAssertion( "ammonium transport") -AnnotationAssertion( "ammonium membrane transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072488") -AnnotationAssertion(rdfs:comment "Note that this term is not intended for use in annotating lateral movement within membranes.") -AnnotationAssertion(rdfs:label "ammonium transmembrane transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (seminiferous tubule development) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mah") Annotation( "UBERON:0001343") "The reproductive developmental process whose specific outcome is the progression of the seminiferous tubule over time, from its formation to the mature structure. Seminiferous tubules are ducts located in the testicles, and are the specific location of meiosis, and the subsequent creation of gametes, namely spermatozoa.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2011-01-04T12:50:36Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072520") -AnnotationAssertion(rdfs:label "seminiferous tubule development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (purine-containing compound metabolic process) - -AnnotationAssertion(Annotation( "GOC:mah") "The chemical reactions and pathways involving a purine-containing compound, i.e. any compound that contains purine or a formal derivative thereof.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2011-01-04T03:03:59Z") -AnnotationAssertion( "purine and derivative metabolic process") -AnnotationAssertion(Annotation( "GOC:mah") "purine-containing compound metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072521") -AnnotationAssertion(rdfs:label "purine-containing compound metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (purine-containing compound biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:mah") "The chemical reactions and pathways resulting in the formation of a purine-containing compound, i.e. any compound that contains purine or a formal derivative thereof.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2011-01-04T03:15:29Z") -AnnotationAssertion( "purine and derivative biosynthetic process") -AnnotationAssertion(Annotation( "GOC:mah") "purine-containing compound anabolism") -AnnotationAssertion(Annotation( "GOC:mah") "purine-containing compound biosynthesis") -AnnotationAssertion(Annotation( "GOC:mah") "purine-containing compound formation") -AnnotationAssertion(Annotation( "GOC:mah") "purine-containing compound synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072522") -AnnotationAssertion(rdfs:label "purine-containing compound biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (purine-containing compound catabolic process) - -AnnotationAssertion(Annotation( "GOC:mah") "The chemical reactions and pathways resulting in the breakdown of a purine-containing compound, i.e. any compound that contains purine or a formal derivative thereof.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2011-01-04T03:17:20Z") -AnnotationAssertion( "purine and derivative catabolic process") -AnnotationAssertion(Annotation( "GOC:mah") "purine-containing compound breakdown") -AnnotationAssertion(Annotation( "GOC:mah") "purine-containing compound catabolism") -AnnotationAssertion(Annotation( "GOC:mah") "purine-containing compound degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072523") -AnnotationAssertion(rdfs:label "purine-containing compound catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (purine-containing compound transmembrane transport) - -AnnotationAssertion(Annotation( "GOC:mah") "The process in which a purine-containing compound is transported across a membrane. A purine-containing compound is any compound that contains purine or a formal derivative thereof.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2011-01-05T01:45:14Z") -AnnotationAssertion( "purine-containing compound membrane transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072530") -AnnotationAssertion(rdfs:comment "Note that this term is not intended for use in annotating lateral movement within membranes.") -AnnotationAssertion(rdfs:label "purine-containing compound transmembrane transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (fibroblast activation) - -AnnotationAssertion(Annotation( "CL:0000057") Annotation( "GOC:BHF") Annotation( "GOC:mah") "A change in the morphology or behavior of a fibroblast resulting from exposure to an activating factor such as a cellular or soluble ligand.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2011-01-14T04:35:08Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072537") -AnnotationAssertion(rdfs:label "fibroblast activation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (type B pancreatic cell maturation) - -AnnotationAssertion(Annotation( "CL:0000169") Annotation( "GOC:BHF") "A developmental process, independent of morphogenetic (shape) change, that is required for a type B pancreatic cell to attain its fully functional state. A type B pancreatic cell is a cell located towards center of the islets of Langerhans that secretes insulin.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2011-01-27T01:57:14Z") -AnnotationAssertion(Annotation( "CL:0000169") Annotation( "GOC:mah") "pancreatic B cell maturation") -AnnotationAssertion(Annotation( "CL:0000169") Annotation( "GOC:mah") "pancreatic beta cell maturation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072560") -AnnotationAssertion(rdfs:comment "These processes continue to 60 DPA in Gossypium spp.") -AnnotationAssertion(rdfs:label "type B pancreatic cell maturation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (epithelial cell proliferation involved in liver morphogenesis) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mah") "The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population that contributes to the shaping of the liver.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2011-02-02T03:37:50Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072575") -AnnotationAssertion(rdfs:label "epithelial cell proliferation involved in liver morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (liver morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mah") "The process in which the anatomical structures of the liver are generated and organized.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2011-02-02T03:41:30Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072576") -AnnotationAssertion(rdfs:label "liver morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (endothelial cell apoptotic process) - -AnnotationAssertion(Annotation( "CL:0000115") Annotation( "GOC:BHF") Annotation( "GOC:mah") Annotation( "GOC:mtg_apoptosis") "Any apoptotic process in an endothelial cell. An endothelial cell comprises the outermost layer or lining of anatomical structures and can be squamous or cuboidal.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2011-02-02T03:56:24Z") -AnnotationAssertion(Annotation( "GOC:mah") "apoptosis of endothelial cells") -AnnotationAssertion(Annotation( "GOC:mah") "endothelial cell programmed cell death by apoptosis") -AnnotationAssertion(Annotation( "GOC:mah") "killing of endothelial cells") -AnnotationAssertion(Annotation( "GOC:mah") "programmed cell death of endothelial cells by apoptosis") -AnnotationAssertion(Annotation( "GOC:mah") "programmed cell death, endothelial cells") -AnnotationAssertion( "endothelial cell apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072577") -AnnotationAssertion(rdfs:label "endothelial cell apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (oxygen metabolic process) - -AnnotationAssertion(Annotation( "GOC:mah") "The chemical reactions and pathways involving diatomic oxygen (O2).") -AnnotationAssertion( "mah") -AnnotationAssertion( "2011-02-11T10:46:51Z") -AnnotationAssertion(Annotation( "CHEBI:33263") "diatomic oxygen metabolic process") -AnnotationAssertion(Annotation( "GOC:mah") "oxygen metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072592") -AnnotationAssertion(rdfs:label "oxygen metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (establishment of protein localization to organelle) - -AnnotationAssertion(Annotation( "GOC:mah") "The directed movement of a protein to a specific location on or in an organelle. Encompasses establishment of localization in the membrane or lumen of a membrane-bounded organelle.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2011-02-14T01:56:51Z") -AnnotationAssertion(Annotation( "GOC:mah") "establishment of protein localisation to organelle") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072594") -AnnotationAssertion(rdfs:label "establishment of protein localization to organelle") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (maintenance of protein localization in organelle) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process in which a protein is maintained in a specific location a specific location on or in an organelle, and is prevented from moving elsewhere. Encompasses establishment of localization in the membrane or lumen of a membrane-bounded organelle.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2011-02-14T02:09:13Z") -AnnotationAssertion(Annotation( "GOC:mah") "maintenance of protein localisation to organelle") -AnnotationAssertion( "maintenance of protein localization to organelle") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072595") -AnnotationAssertion(rdfs:label "maintenance of protein localization in organelle") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (protein localization to membrane) - -AnnotationAssertion(Annotation( "GOC:mah") "A process in which a protein is transported to, or maintained in, a specific location in a membrane.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2011-02-14T02:35:18Z") -AnnotationAssertion(Annotation( "GOC:mah") "protein localisation in membrane") -AnnotationAssertion( "protein localization in membrane") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072657") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "protein localization to membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (protein localization to plasma membrane) - -AnnotationAssertion(Annotation( "GOC:mah") "A process in which a protein is transported to, or maintained in, a specific location in the plasma membrane.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2009-07-10T10:29:23Z") -AnnotationAssertion( "GO:0072661") -AnnotationAssertion( "GO:0090002") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:mah") "protein localisation in plasma membrane") -AnnotationAssertion( "protein localization in plasma membrane") -AnnotationAssertion( "protein targeting to plasma membrane") -AnnotationAssertion(Annotation( "GOC:mah") "protein-plasma membrane targeting") -AnnotationAssertion( "GO:0072659") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "protein localization to plasma membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (protein localization to vacuole) - -AnnotationAssertion(Annotation( "GOC:ecd") "A process in which a protein is transported to, or maintained at, a location in a vacuole.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2011-02-14T02:55:35Z") -AnnotationAssertion(Annotation( "GOC:mah") "protein localisation to vacuole") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072665") -AnnotationAssertion(rdfs:label "protein localization to vacuole") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (establishment of protein localization to vacuole) - -AnnotationAssertion(Annotation( "GOC:mah") "The directed movement of a protein to a specific location in a vacuole.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2011-02-14T02:56:29Z") -AnnotationAssertion(Annotation( "GOC:mah") "establishment of protein localisation to vacuole") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072666") -AnnotationAssertion(rdfs:label "establishment of protein localization to vacuole") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (maintenance of protein location in vacuole) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process in which a protein is maintained in a specific location in a vacuole, and is prevented from moving elsewhere.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2011-02-14T02:56:57Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072667") -AnnotationAssertion(rdfs:label "maintenance of protein location in vacuole") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (multinuclear osteoclast differentiation) - -AnnotationAssertion(Annotation( "CL:0000779") Annotation( "GOC:mah") Annotation( "PMID:12713016") "The process in which a relatively unspecialized monocyte acquires the specialized features of a multinuclear osteoclast. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2011-02-22T02:10:38Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mah") "multinuclear osteoclast formation") -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mah") "multinuclear osteoclast morphogenesis") -AnnotationAssertion( "GO:0072674") -AnnotationAssertion(rdfs:label "multinuclear osteoclast differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (lymphocyte migration) - -AnnotationAssertion(Annotation( "CL:0000542") Annotation( "GOC:BHF") Annotation( "GOC:mah") "The movement of a lymphocyte within or between different tissues and organs of the body.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2011-02-22T03:38:12Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072676") -AnnotationAssertion(rdfs:label "lymphocyte migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (T cell migration) - -AnnotationAssertion(Annotation( "CL:0000084") Annotation( "GOC:BHF") Annotation( "GOC:mah") "The movement of a T cell within or between different tissues and organs of the body.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2011-02-22T03:40:40Z") -AnnotationAssertion(Annotation( "CL:0000084") "T lymphocyte migration") -AnnotationAssertion(Annotation( "CL:0000084") "T-cell migration") -AnnotationAssertion(Annotation( "CL:0000084") "T-lymphocyte migration") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072678") -AnnotationAssertion(rdfs:label "T cell migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (thymocyte migration) - -AnnotationAssertion(Annotation( "CL:0000893") Annotation( "GOC:BHF") Annotation( "GOC:mah") "The movement of a thymocyte through distinct intrathymic niches (e.g. medulla, cortex), where it receives a unique set of developmental cues required for T-cell development.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2011-02-22T03:47:51Z") -AnnotationAssertion(Annotation( "CL:0000893") "thymic lymphocyte migration") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "CL:0000893") "immature T cell migration") -AnnotationAssertion(Annotation( "CL:0000893") "immature T lymphocyte migration") -AnnotationAssertion(Annotation( "CL:0000893") "immature T-cell migration") -AnnotationAssertion(Annotation( "CL:0000893") "immature T-lymphocyte migration") -AnnotationAssertion( "GO:0072679") -AnnotationAssertion(rdfs:label "thymocyte migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (protein localization to cell cortex) - -AnnotationAssertion(Annotation( "GOC:mah") "A process in which a protein is transported to, or maintained in, the cell cortex.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2012-04-11T01:16:33Z") -AnnotationAssertion(Annotation( "GOC:mah") "protein localisation to cell cortex") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072697") -AnnotationAssertion(rdfs:label "protein localization to cell cortex") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (protein localization to microtubule cytoskeleton) - -AnnotationAssertion(Annotation( "GOC:mah") "A cellular protein localization process in which a protein is transported to, or maintained at, a location within the microtubule cytoskeleton.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2012-04-11T01:19:35Z") -AnnotationAssertion(Annotation( "GOC:mah") "protein localisation to microtubule cytoskeleton") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0072698") -AnnotationAssertion(rdfs:label "protein localization to microtubule cytoskeleton") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of primary metabolic process) - -AnnotationAssertion(Annotation( "PMID:19211694") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism involving those compounds formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.") -AnnotationAssertion( "dhl") -AnnotationAssertion( "2009-04-22T04:30:52Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0080090") -AnnotationAssertion(rdfs:label "regulation of primary metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - # Class: (regulation of response to stress) AnnotationAssertion(Annotation( "GOC:dhl") "Any process that modulates the frequency, rate or extent of a response to stress. Response to stress is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).") @@ -109534,339 +27469,8 @@ AnnotationAssertion( ) AnnotationAssertion(rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.") AnnotationAssertion(rdfs:label "regulation of response to stress") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (intracellular amino acid homeostasis) - -AnnotationAssertion(Annotation( "PMID:19955263") "A homeostatic process involved in the maintenance of a steady state level of amino acids within a cell.") -AnnotationAssertion( "dhl") -AnnotationAssertion( "2010-01-27T04:47:27Z") -AnnotationAssertion( "amino acid homeostasis") -AnnotationAssertion( "cellular amino acid homeostasis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0080144") -AnnotationAssertion(rdfs:label "intracellular amino acid homeostasis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of fertilization) - -AnnotationAssertion(Annotation( "GOC:DHL") Annotation( "PMID:20478994") "Any process that modulates the rate, frequency or extent of fertilization. Fertilization is the union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy).") -AnnotationAssertion( "dhl") -AnnotationAssertion( "2010-09-01T03:44:27Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0080154") -AnnotationAssertion(rdfs:label "regulation of fertilization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (lytic vacuole organization) - -AnnotationAssertion(Annotation( "PMID:20729380") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lytic vacuole.") -AnnotationAssertion( "dhl") -AnnotationAssertion( "2011-04-25T04:40:46Z") -AnnotationAssertion( "lytic vacuole organisation") -AnnotationAssertion( "lytic vacuolar assembly") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "lytic vacuole biogenesis") -AnnotationAssertion( "lytic vacuole organization and biogenesis") -AnnotationAssertion( "GO:0080171") -AnnotationAssertion(rdfs:label "lytic vacuole organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (extracellular matrix assembly) - -AnnotationAssertion(Annotation( "GOC:jl") "The aggregation, arrangement and bonding together of the extracellular matrix.") -AnnotationAssertion( "jl") -AnnotationAssertion( "2010-07-14T12:52:49Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0085029") -AnnotationAssertion(rdfs:label "extracellular matrix assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (cardiac muscle cell action potential) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mtg_cardiac_conduct_nov11") "An action potential that occurs in a cardiac muscle cell.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2011-11-10T07:45:11Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0086001") -AnnotationAssertion(rdfs:label "cardiac muscle cell action potential") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (SA node cell action potential) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mtg_cardiac_conduct_nov11") "An action potential that occurs in a sinoatrial node cardiac muscle cell.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2011-11-10T08:50:15Z") -AnnotationAssertion( "SA node cardiac muscle cell action potential") -AnnotationAssertion( "SAN cardiac muscle cell action potential") -AnnotationAssertion( "sinoatrial node cardiac muscle cell action potential") -AnnotationAssertion( "sinus node cardiac muscle cell action potential") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0086015") -AnnotationAssertion(rdfs:label "SA node cell action potential") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (AV node cell action potential) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mtg_cardiac_conduct_nov11") "An action potential that occurs in an atrioventricular node cardiac muscle cell.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2011-11-10T08:58:56Z") -AnnotationAssertion( "AV node cardiac muscle cell action potential") -AnnotationAssertion( "atrioventricular node cardiac muscle cell action potential") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0086016") -AnnotationAssertion(rdfs:label "AV node cell action potential") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (Purkinje myocyte action potential) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mtg_cardiac_conduct_nov11") "An action potential that occurs in a Purkinje myocyte.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2011-11-10T08:58:56Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0086017") -AnnotationAssertion(rdfs:label "Purkinje myocyte action potential") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (SA node cell to atrial cardiac muscle cell signaling) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mtg_cardiac_conduct_nov11") "Any process that mediates the transfer of information from an SA node cardiomyocyte to an atrial cardiomyocyte.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2011-11-10T09:15:01Z") -AnnotationAssertion( "SA node cardiac muscle cell to atrial cardiac muscle cell signalling") -AnnotationAssertion( "SA node cardiomyocyte to atrial cardiomyocyte signalling") -AnnotationAssertion( "SAN cardiomyocyte to atrial cardiomyocyte signalling") -AnnotationAssertion( "sinoatrial node cardiomyocyte to atrial cardiomyocyte signalling") -AnnotationAssertion( "sinus node cardiomyocyte to atrial cardiomyocyte signalling") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0086018") -AnnotationAssertion(rdfs:label "SA node cell to atrial cardiac muscle cell signaling") -SubClassOf( ) -SubClassOf( ) - -# Class: (cell-cell signaling involved in cardiac conduction) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mtg_cardiac_conduct_nov11") "Any process that mediates the transfer of information from one cell to another and contributes to the heart process that regulates cardiac muscle contraction; beginning with the generation of an action potential in the sinoatrial node and ending with regulation of contraction of the myocardium.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2011-11-16T03:43:52Z") -AnnotationAssertion(Annotation( "GOC:mah") "cell-cell signalling involved in cardiac conduction") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0086019") -AnnotationAssertion(rdfs:label "cell-cell signaling involved in cardiac conduction") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (AV node cell to bundle of His cell signaling) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mtg_cardiac_conduct_nov11") "Any process that mediates the transfer of information from an AV node cardiac muscle cell to a bundle of His cardiomyocyte.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2011-11-11T02:02:14Z") -AnnotationAssertion(Annotation( "GOC:mah") "AV node cell to bundle of His cell signalling") -AnnotationAssertion( "atrioventricular node to bundle of His cell signaling") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0086027") -AnnotationAssertion(rdfs:label "AV node cell to bundle of His cell signaling") -SubClassOf( ) -SubClassOf( ) - -# Class: (bundle of His cell to Purkinje myocyte signaling) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mtg_cardiac_conduct_nov11") "Any process that mediates the transfer of information from a bundle of His cardiomyocyte to a Purkinje myocyte.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2011-11-11T02:02:14Z") -AnnotationAssertion( "bundle of His cardiac muscle cell to Purkinje myocyte signaling") -AnnotationAssertion(Annotation( "GOC:mah") "bundle of His cardiac muscle cell to Purkinje myocyte signalling") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0086028") -AnnotationAssertion(rdfs:label "bundle of His cell to Purkinje myocyte signaling") -SubClassOf( ) -SubClassOf( ) - -# Class: (Purkinje myocyte to ventricular cardiac muscle cell signaling) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mtg_cardiac_conduct_nov11") "Any process that mediates the transfer of information from a Purkinje myocyte to a ventricular cardiac muscle cell.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2011-11-11T02:02:14Z") -AnnotationAssertion(Annotation( "GOC:mah") "Purkinje myocyte to ventricular cardiac muscle cell signalling") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0086029") -AnnotationAssertion(rdfs:label "Purkinje myocyte to ventricular cardiac muscle cell signaling") -SubClassOf( ) -SubClassOf( ) - -# Class: (bundle of His cell action potential) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mtg_cardiac_conduct_nov11") "An action potential that occurs in a bundle of His cell.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2011-11-15T12:01:18Z") -AnnotationAssertion( "bundle of His cardiac muscle cell action potential") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0086043") -AnnotationAssertion(rdfs:label "bundle of His cell action potential") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cell communication involved in cardiac conduction) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mtg_cardiac_conduct_nov11") "Any process that mediates interactions between a cell and its surroundings that contributes to the process of cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2011-11-22T08:57:02Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0086065") -AnnotationAssertion(rdfs:label "cell communication involved in cardiac conduction") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (AV node cell to bundle of His cell communication) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mtg_cardiac_conduct_nov11") "The process that mediates interactions between an AV node cell and its surroundings that contributes to the process of the AV node cell communicating with a bundle of His cell in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2011-11-22T09:11:44Z") -AnnotationAssertion( "atrioventricular node cell to bundle of His cell communication") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0086067") -AnnotationAssertion(rdfs:label "AV node cell to bundle of His cell communication") -SubClassOf( ) - -# Class: (Purkinje myocyte to ventricular cardiac muscle cell communication) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mtg_cardiac_conduct_nov11") "The process that mediates interactions between a Purkinje myocyte and its surroundings that contributes to the process of the Purkinje myocyte communicating with a ventricular cardiac muscle cell in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2011-11-22T09:14:49Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0086068") -AnnotationAssertion(rdfs:label "Purkinje myocyte to ventricular cardiac muscle cell communication") -SubClassOf( ) - -# Class: (bundle of His cell to Purkinje myocyte communication) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mtg_cardiac_conduct_nov11") "The process that mediates interactions between a bundle of His cell and its surroundings that contributes to the process of the bundle of His cell communicating with a Purkinje myocyte in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/20731"^^xsd:anyURI) -AnnotationAssertion( "dph") -AnnotationAssertion( "2011-11-22T09:18:49Z") -AnnotationAssertion( "bundle of His cardiac muscle cell to Purkinje myocyte communication") -AnnotationAssertion( "ventricular conduction system cell to cell communication") -AnnotationAssertion( "atrioventricular junction myocyte to bundle branch myocyte") -AnnotationAssertion( "bundle branch myocyte to Purkinje myocyte communication") -AnnotationAssertion( "bundle of His myocyte to atrioventricular junction myocyte") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0086069") -AnnotationAssertion(rdfs:label "bundle of His cell to Purkinje myocyte communication") -SubClassOf( ) - -# Class: (SA node cell to atrial cardiac muscle cell communication) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mtg_cardiac_conduct_nov11") "The process that mediates interactions between an SA node cardiomyocyte and its surroundings that contributes to the process of the SA node cardiomyocyte communicating with an atrial cardiomyocyte in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2011-11-22T09:32:45Z") -AnnotationAssertion( "SA node cardiac muscle cell to atrial cardiac muscle cell communication") -AnnotationAssertion( "SA node cardiomyocyte to atrial cardiomyocyte communication") -AnnotationAssertion( "SAN cardiomyocyte to atrial cardiomyocyte communication") -AnnotationAssertion( "sinoatrial node cardiomyocyte to atrial cardiomyocyte communication") -AnnotationAssertion( "sinus node cardiomyocyte to atrial cardiomyocyte communication") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0086070") -AnnotationAssertion(rdfs:label "SA node cell to atrial cardiac muscle cell communication") -SubClassOf( ) - -# Class: (G protein-coupled acetylcholine receptor signaling pathway involved in heart process) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mtg_cardiac_conduct_nov11") "A G protein-coupled acetylcholine receptor signaling pathway, which contributes to a circulatory system process carried out by the heart.") -AnnotationAssertion( "bf") -AnnotationAssertion( "G-protein coupled acetylcholine receptor signaling pathway involved in heart process") -AnnotationAssertion(Annotation( "GOC:bf") "G-protein coupled acetylcholine receptor signalling pathway involved in heart process") -AnnotationAssertion(Annotation( "GOC:mtg_cardiac_conduct_nov11") "M2 receptor signaling pathway involved in heart process") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:mtg_cardiac_conduct_nov11") "muscarinic receptor signaling pathway involved in heart process") -AnnotationAssertion( "GO:0086093") -AnnotationAssertion(rdfs:label "G protein-coupled acetylcholine receptor signaling pathway involved in heart process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (G protein-coupled receptor signaling pathway involved in heart process) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mtg_cardiac_conduct_nov11") Annotation( "PMID:17376402") "An G protein-coupled receptor signaling pathway which contributes to a circulatory system process carried out by the heart.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2012-03-19T01:28:23Z") -AnnotationAssertion(Annotation( "GOC:bf") "G-protein coupled receptor signaling pathway involved in heart process") -AnnotationAssertion(Annotation( "GOC:bf") "G-protein coupled receptor signalling pathway involved in heart process") -AnnotationAssertion(Annotation( "GOC:bf") "GPCR signaling pathway involved in cardiac process") -AnnotationAssertion(Annotation( "GOC:bf") "GPCR signaling pathway involved in heart process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0086103") -AnnotationAssertion(rdfs:label "G protein-coupled receptor signaling pathway involved in heart process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (L-glutamate transmembrane export from vacuole) - -AnnotationAssertion(Annotation( "PMID:21307582") "The directed movement of L-glutamate out of the vacuole, across the vacuolar membrane.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0089704") -AnnotationAssertion(rdfs:label "L-glutamate transmembrane export from vacuole") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (amino acid import across plasma membrane) - -AnnotationAssertion(Annotation( "GOC:krc") Annotation( "PMID:8195186") "The directed movement of an amino acid from outside of a cell, across the plasma membrane and into the cytosol.") -AnnotationAssertion( "jl") -AnnotationAssertion( "2012-11-14T14:21:41Z") -AnnotationAssertion( "GO:0043092") -AnnotationAssertion( "GO:0044745") -AnnotationAssertion( "GO:1902837") -AnnotationAssertion( "L-amino acid import") -AnnotationAssertion( "amino acid transmembrane import") -AnnotationAssertion( "amino acid import into cell") -AnnotationAssertion( "L-amino acid uptake") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0089718") -AnnotationAssertion(rdfs:label "amino acid import across plasma membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (hypoblast development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:sdb_2009") Annotation( "GOC:tb") "The process whose specific outcome is the progression of the hypoblast over time, from its formation to the mature structure. The hypoblast is a tissue formed from the inner cell mass that lies beneath the epiblast.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2009-07-29T10:25:54Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0090008") -AnnotationAssertion(rdfs:label "hypoblast development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (primitive streak formation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:sdb_2009") Annotation( "GOC:tb") "The developmental process pertaining to the initial formation of the primitive streak from unspecified parts. The primitive streak is a ridge of cells running along the midline of the embryo where the mesoderm ingresses. It defines the anterior-posterior axis.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2009-07-29T10:31:31Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0090009") -AnnotationAssertion(rdfs:label "primitive streak formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (regulation of neutrophil chemotaxis) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the frequency, rate, or extent of neutrophil chemotaxis. Neutrophil chemotaxis is the directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2009-08-03T10:09:34Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0090022") -AnnotationAssertion(rdfs:label "regulation of neutrophil chemotaxis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (positive regulation of neutrophil chemotaxis) AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that increases the frequency, rate, or extent of neutrophil chemotaxis. Neutrophil chemotaxis is the directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding.") @@ -109875,949 +27479,6 @@ AnnotationAssertion( AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0090023") AnnotationAssertion(rdfs:label "positive regulation of neutrophil chemotaxis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of neutrophil chemotaxis) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that decreases the frequency, rate, or extent of neutrophil chemotaxis. Neutrophil chemotaxis is the directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2009-08-03T10:13:09Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0090024") -AnnotationAssertion(rdfs:label "negative regulation of neutrophil chemotaxis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of monocyte chemotaxis) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the frequency, rate, or extent of monocyte chemotaxis.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2009-08-03T10:17:03Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0090025") -AnnotationAssertion(rdfs:label "regulation of monocyte chemotaxis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of monocyte chemotaxis) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that increases the frequency, rate, or extent of monocyte chemotaxis.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2009-08-03T10:18:54Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0090026") -AnnotationAssertion(rdfs:label "positive regulation of monocyte chemotaxis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of monocyte chemotaxis) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that decreases the frequency, rate, or extent of monocyte chemotaxis.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2009-08-03T10:19:40Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0090027") -AnnotationAssertion(rdfs:label "negative regulation of monocyte chemotaxis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of steroid hormone biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroid hormones,compounds with a 1, 2, cyclopentanoperhydrophenanthrene nucleus that act as hormones.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2009-08-03T10:38:27Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0090030") -AnnotationAssertion(rdfs:label "regulation of steroid hormone biosynthetic process") -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of steroid hormone biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroid hormones,compounds with a 1, 2, cyclopentanoperhydrophenanthrene nucleus that act as hormones.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2009-08-03T10:40:32Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0090031") -AnnotationAssertion(rdfs:label "positive regulation of steroid hormone biosynthetic process") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of steroid hormone biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroid hormones,compounds with a 1, 2, cyclopentanoperhydrophenanthrene nucleus that act as hormones.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2009-08-03T10:41:35Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0090032") -AnnotationAssertion(rdfs:label "negative regulation of steroid hormone biosynthetic process") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of microtubule nucleation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that increases the rate, frequency or extent of microtubule nucleation. Microtubule nucleation is the 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2009-08-12T11:33:09Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0090063") -AnnotationAssertion(rdfs:label "positive regulation of microtubule nucleation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of cell cycle process) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that increases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2009-09-09T11:39:52Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0090068") -AnnotationAssertion(rdfs:label "positive regulation of cell cycle process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of ribosome biogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis is the cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2009-09-11T10:32:17Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0090069") -AnnotationAssertion(rdfs:label "regulation of ribosome biogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of ribosome biogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that increases the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis is the cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2009-09-11T10:32:17Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0090070") -AnnotationAssertion(rdfs:label "positive regulation of ribosome biogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of ribosome biogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that decreases the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis is the cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2009-09-11T10:32:17Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0090071") -AnnotationAssertion(rdfs:label "negative regulation of ribosome biogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of peptide transport) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the frequency, rate or extent of the directed movement of peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2009-10-23T11:21:38Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0090087") -AnnotationAssertion(rdfs:label "regulation of peptide transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (positive regulation of extracellular matrix disassembly) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that increases the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2009-11-04T10:03:25Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0090091") -AnnotationAssertion(rdfs:label "positive regulation of extracellular matrix disassembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cochlea development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "The progression of the cochlea over time from its formation to the mature structure. The cochlea is the snail-shaped portion of the inner ear that is responsible for the detection of sound.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2009-11-18T11:42:15Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0090102") -AnnotationAssertion(rdfs:label "cochlea development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cochlea morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "The process in which the cochlea is generated and organized.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2009-11-18T11:45:11Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0090103") -AnnotationAssertion(rdfs:label "cochlea morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (tissue migration) - -AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "The process in which the population of cells that make up a tissue undergo directed movement.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2009-12-07T03:13:55Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0090130") -AnnotationAssertion(rdfs:label "tissue migration") -SubClassOf( ) - -# Class: (mesenchyme migration) - -AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "The process in which the population of cells that make up a mesenchyme undergo directed movement.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2009-12-07T03:15:17Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0090131") -AnnotationAssertion(rdfs:label "mesenchyme migration") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (epithelium migration) - -AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "The process in which the population of cells that make up an epithelium undergo directed movement.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2009-12-07T03:19:34Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0090132") -AnnotationAssertion(rdfs:label "epithelium migration") -SubClassOf( ) - -# Class: (regulation of actin cytoskeleton organization by cell-cell adhesion) - -AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any cell-cell adhesion process that modulates the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2009-12-08T02:05:00Z") -AnnotationAssertion(Annotation( "GOC:mah") "regulation of actin cytoskeleton organisation by cell-cell adhesion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0090138") -AnnotationAssertion(rdfs:label "regulation of actin cytoskeleton organization by cell-cell adhesion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (establishment of protein localization to membrane) - -AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "The directed movement of a protein to a specific location in a membrane.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2009-12-08T03:18:51Z") -AnnotationAssertion(Annotation( "GOC:mah") "establishment of protein localisation in membrane") -AnnotationAssertion( "establishment of protein localization in membrane") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0090150") -AnnotationAssertion(rdfs:label "establishment of protein localization to membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of sphingolipid biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the rate, frequency or extent of sphingolipid biosynthesis. Sphingolipid biosynthesis is the chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).") -AnnotationAssertion( "tb") -AnnotationAssertion( "2009-12-08T03:25:49Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0090153") -AnnotationAssertion(rdfs:label "regulation of sphingolipid biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of sphingolipid biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that increases the rate, frequency or extent of sphingolipid biosynthesis. Sphingolipid biosynthesis is the chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).") -AnnotationAssertion( "tb") -AnnotationAssertion( "2009-12-08T03:27:33Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0090154") -AnnotationAssertion(rdfs:label "positive regulation of sphingolipid biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of sphingolipid biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that decreases the rate, frequency or extent of sphingolipid biosynthesis. Sphingolipid biosynthesis is the chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).") -AnnotationAssertion( "tb") -AnnotationAssertion( "2009-12-08T03:33:39Z") -AnnotationAssertion( "GO:0090157") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "negative regulation of sphingolipid biosynthesis involved in cellular sphingolipid homeostasis") -AnnotationAssertion( "GO:0090155") -AnnotationAssertion(rdfs:label "negative regulation of sphingolipid biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (intracellular sphingolipid homeostasis) - -AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "A homeostatic process involved in the maintenance of a steady state level of sphingolipids within a cell.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2009-12-08T08:21:36Z") -AnnotationAssertion( "cellular sphingolipid homeostasis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0090156") -AnnotationAssertion(rdfs:label "intracellular sphingolipid homeostasis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (Golgi to lysosome transport) - -AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "The directed movement of substances from the Golgi to lysosomes.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2009-12-08T08:35:13Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0090160") -AnnotationAssertion(rdfs:label "Golgi to lysosome transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (establishment of epithelial cell polarity) - -AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "The specification and formation of anisotropic intracellular organization of an epithelial cell.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2009-12-08T08:58:27Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0090162") -AnnotationAssertion(rdfs:label "establishment of epithelial cell polarity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (Golgi disassembly) - -AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "A cellular process that results in the breakdown of a Golgi apparatus that contributes to Golgi inheritance.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2009-12-08T09:15:11Z") -AnnotationAssertion( "Golgi apparatus disassembly") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0090166") -AnnotationAssertion(rdfs:label "Golgi disassembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (Golgi reassembly) - -AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "The reformation of the Golgi following its breakdown and partitioning contributing to Golgi inheritance.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2009-12-08T09:15:11Z") -AnnotationAssertion( "Golgi apparatus reassembly") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0090168") -AnnotationAssertion(rdfs:label "Golgi reassembly") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (regulation of Golgi inheritance) - -AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the rate, frequency or extent of Golgi inheritance. Golgi inheritance is the partitioning of Golgi apparatus between daughter cells at cell division.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2009-12-11T10:21:59Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0090170") -AnnotationAssertion(rdfs:label "regulation of Golgi inheritance") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (chondrocyte morphogenesis) - -AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "The process in which the structures of a chondrocyte are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a chondrocyte.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2009-12-11T10:36:02Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0090171") -AnnotationAssertion(rdfs:label "chondrocyte morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (organelle membrane fusion) - -AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "The joining of two lipid bilayers to form a single organelle membrane.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2009-12-11T11:44:58Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0090174") -AnnotationAssertion(rdfs:label "organelle membrane fusion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of kidney development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") Annotation( "GOC:yaf") "Any process that modulates the rate, frequency or extent of kidney development. Kidney development is the process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2009-12-18T10:50:56Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "regulation of nephrogenesis") -AnnotationAssertion( "GO:0090183") -AnnotationAssertion(rdfs:label "regulation of kidney development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of kidney development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") Annotation( "GOC:yaf") "Any process that increases the rate, frequency or extent of kidney development. Kidney development is the process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2009-12-18T10:52:01Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "positive regulation of nephrogenesis") -AnnotationAssertion( "GO:0090184") -AnnotationAssertion(rdfs:label "positive regulation of kidney development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (negative regulation of kidney development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") Annotation( "GOC:yaf") "Any process that decreases the rate, frequency or extent of kidney development. Kidney development is the process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2009-12-18T10:58:45Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "negative regulation of nephrogenesis") -AnnotationAssertion( "GO:0090185") -AnnotationAssertion(rdfs:label "negative regulation of kidney development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of branching involved in ureteric bud morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") Annotation( "GOC:yaf") "Any process that modulates the rate, frequency or extent of branching involved in ureteric bud morphogenesis, the process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2009-12-18T11:11:17Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0090189") -AnnotationAssertion(rdfs:label "regulation of branching involved in ureteric bud morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of branching involved in ureteric bud morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") Annotation( "GOC:yaf") "Any process that increases the rate, frequency or extent of branching involved in ureteric bud morphogenesis, the process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2009-12-18T11:11:17Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0090190") -AnnotationAssertion(rdfs:label "positive regulation of branching involved in ureteric bud morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of branching involved in ureteric bud morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") Annotation( "GOC:yaf") "Any process that decreases the rate, frequency or extent of branching involved in ureteric bud morphogenesis, the process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2009-12-18T11:11:17Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0090191") -AnnotationAssertion(rdfs:label "negative regulation of branching involved in ureteric bud morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of glomerulus development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") Annotation( "GOC:yaf") "Any process that modulates the rate, frequency or extent of glomerulus development, the progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2009-12-18T11:17:13Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0090192") -AnnotationAssertion(rdfs:label "regulation of glomerulus development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of glomerulus development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") Annotation( "GOC:yaf") "Any process that increases the rate, frequency or extent of glomerulus development, the progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2009-12-18T11:17:13Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0090193") -AnnotationAssertion(rdfs:label "positive regulation of glomerulus development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (negative regulation of glomerulus development) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") Annotation( "GOC:yaf") "Any process that decreases the rate, frequency or extent of glomerulus development, the progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2009-12-18T11:17:13Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0090194") -AnnotationAssertion(rdfs:label "negative regulation of glomerulus development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (spongiotrophoblast layer developmental growth) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "The increase in size or mass of the spongiotrophoblast layer of the placenta where the increase in size or mass contributes to the progression of that layer over time from its formation to its mature state.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2010-01-08T12:10:44Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0090214") -AnnotationAssertion(rdfs:label "spongiotrophoblast layer developmental growth") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (epithelium migration involved in imaginal disc-derived wing morphogenesis) - -AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "The process in which the population of cells that make up a wing epithelium undergo directed movement and contribute to imaginal disc-derived morphogenesis.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2010-01-22T11:40:46Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0090252") -AnnotationAssertion(rdfs:label "epithelium migration involved in imaginal disc-derived wing morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cell proliferation involved in imaginal disc-derived wing morphogenesis) - -AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to imaginal disc-derived wing morphogenesis.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2010-01-22T11:40:46Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0090255") -AnnotationAssertion(rdfs:label "cell proliferation involved in imaginal disc-derived wing morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of cell proliferation involved in imaginal disc-derived wing morphogenesis) - -AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the frequency, rate, or extent of the multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to imaginal disc-derived wing morphogenesis.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2010-01-22T11:40:46Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0090256") -AnnotationAssertion(rdfs:label "regulation of cell proliferation involved in imaginal disc-derived wing morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (regulation of muscle system process) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the frequency, rate or extent of a muscle system process, a multicellular organismal process carried out by any of the organs or tissues in a muscle system.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2010-02-03T11:48:13Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0090257") -AnnotationAssertion(rdfs:label "regulation of muscle system process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of somatostatin secretion) - -AnnotationAssertion(Annotation( "GOC:BHF") "Any process that modulates the rate, frequency, extent of the regulated release of somatostatin from secretory granules in the D cells of the pancreas.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2010-02-05T02:54:14Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0090273") -AnnotationAssertion(rdfs:label "regulation of somatostatin secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (positive regulation of somatostatin secretion) - -AnnotationAssertion(Annotation( "GOC:BHF") "Any process that increases the rate, frequency, extent of the regulated release of somatostatin from secretory granules in the D cells of the pancreas.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2010-02-05T02:54:14Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0090274") -AnnotationAssertion(rdfs:label "positive regulation of somatostatin secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of somatostatin secretion) - -AnnotationAssertion(Annotation( "GOC:BHF") "Any process that decreases the rate, frequency, extent of the regulated release of somatostatin from secretory granules in the D cells of the pancreas.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2010-02-05T02:54:14Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0090275") -AnnotationAssertion(rdfs:label "negative regulation of somatostatin secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of peptide hormone secretion) - -AnnotationAssertion(Annotation( "GOC:tb") "Any process that modulates the rate, frequency, or extent of the regulated release of a peptide hormone from secretory granules.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2010-02-05T02:56:39Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0090276") -AnnotationAssertion(rdfs:label "regulation of peptide hormone secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of peptide hormone secretion) - -AnnotationAssertion(Annotation( "GOC:tb") "Any process that increases the rate, frequency, or extent of the regulated release of a peptide hormone from secretory granules.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2010-02-05T02:56:39Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0090277") -AnnotationAssertion(rdfs:label "positive regulation of peptide hormone secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of peptide hormone secretion) - -AnnotationAssertion(Annotation( "GOC:tb") "Any process that decreases the rate, frequency, or extent of the regulated release of a peptide hormone from secretory granules.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2010-02-05T02:56:39Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0090278") -AnnotationAssertion(rdfs:label "negative regulation of peptide hormone secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of osteoclast proliferation) - -AnnotationAssertion(Annotation( "GOC:tb") "Any process that modulates the rate, frequency, or extent of the multiplication or reproduction of osteoclasts, resulting in the expansion of an osteoclast cell population.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2010-02-18T03:11:03Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0090289") -AnnotationAssertion(rdfs:label "regulation of osteoclast proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of osteoclast proliferation) - -AnnotationAssertion(Annotation( "GOC:tb") "Any process that increases the rate, frequency, or extent of the multiplication or reproduction of osteoclasts, resulting in the expansion of an osteoclast cell population.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2010-02-18T03:11:03Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0090290") -AnnotationAssertion(rdfs:label "positive regulation of osteoclast proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of osteoclast proliferation) - -AnnotationAssertion(Annotation( "GOC:tb") "Any process that decreases the rate, frequency, or extent of the multiplication or reproduction of osteoclasts, resulting in the expansion of an osteoclast cell population.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2010-02-18T03:11:03Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0090291") -AnnotationAssertion(rdfs:label "negative regulation of osteoclast proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of neural crest formation) - -AnnotationAssertion(Annotation( "GOC:tb") "Any process that modulates the rate, frequency, or extent of neural crest formation. Neural crest formation is the formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation proceeds.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2010-03-12T04:08:26Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0090299") -AnnotationAssertion(rdfs:label "regulation of neural crest formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of neural crest formation) - -AnnotationAssertion(Annotation( "GOC:tb") "Any process that increases the rate, frequency, or extent of neural crest formation. Neural crest formation is the formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation procedes.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2010-03-12T04:08:26Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0090300") -AnnotationAssertion(rdfs:label "positive regulation of neural crest formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of neural crest formation) - -AnnotationAssertion(Annotation( "GOC:tb") "Any process that decreases the rate, frequency, or extent of neural crest formation. Neural crest formation is the formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation procedes.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2010-03-12T04:08:26Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0090301") -AnnotationAssertion(rdfs:label "negative regulation of neural crest formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of wound healing) - -AnnotationAssertion(Annotation( "GOC:BHF") "Any process that increases the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2010-03-22T02:12:03Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0090303") -AnnotationAssertion(rdfs:label "positive regulation of wound healing") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (nucleic acid metabolic process) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any cellular metabolic process involving nucleic acids.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2010-04-07T10:18:47Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0090304") -AnnotationAssertion(rdfs:label "nucleic acid metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of intracellular protein transport) - -AnnotationAssertion(Annotation( "GOC:tb") "Any process that activates or increases the frequency, rate or extent of the directed movement of proteins within cells.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2010-04-16T03:45:07Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0090316") -AnnotationAssertion(rdfs:label "positive regulation of intracellular protein transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of intracellular protein transport) - -AnnotationAssertion(Annotation( "GOC:tb") "Any process that decreases the frequency, rate or extent of the directed movement of proteins within cells.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2010-04-16T03:45:07Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0090317") -AnnotationAssertion(rdfs:label "negative regulation of intracellular protein transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (regulation of locomotion involved in locomotory behavior) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:kmv") Annotation( "GOC:tb") "Any process that modulates the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2010-05-14T10:24:29Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0090325") -AnnotationAssertion(rdfs:label "regulation of locomotion involved in locomotory behavior") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of locomotion involved in locomotory behavior) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:kmv") Annotation( "GOC:tb") "Any process that increases the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2010-05-14T10:26:58Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0090326") -AnnotationAssertion(rdfs:label "positive regulation of locomotion involved in locomotory behavior") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of locomotion involved in locomotory behavior) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:kmv") Annotation( "GOC:tb") "Any process that decreases the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2010-05-14T10:26:58Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0090327") -AnnotationAssertion(rdfs:label "negative regulation of locomotion involved in locomotory behavior") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of olfactory learning) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the rate, frequency, or extent of olfactory learning. Olfactory learning is any process in an organism in which a relatively long-lasting adaptive behavioral change occurs in response to (repeated) exposure to an olfactory cue.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2010-05-14T10:37:22Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0090328") -AnnotationAssertion(rdfs:label "regulation of olfactory learning") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of brown fat cell differentiation) - -AnnotationAssertion(Annotation( "GOC:tb") "Any process that modulates the rate, frequency, or extent of brown fat cell differentiation. Brown fat cell differentiation is the process in which a relatively unspecialized cell acquires specialized features of a brown adipocyte, an animal connective tissue cell involved in adaptive thermogenesis. Brown adipocytes contain multiple small droplets of triglycerides and a high number of mitochondria.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2010-06-01T03:16:57Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0090335") -AnnotationAssertion(rdfs:label "regulation of brown fat cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of brown fat cell differentiation) - -AnnotationAssertion(Annotation( "GOC:BHF") "Any process that increases the rate, frequency, or extent of brown fat cell differentiation. Brown fat cell differentiation is the process in which a relatively unspecialized cell acquires specialized features of a brown adipocyte, an animal connective tissue cell involved in adaptive thermogenesis. Brown adipocytes contain multiple small droplets of triglycerides and a high number of mitochondria.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2010-06-01T03:19:26Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0090336") -AnnotationAssertion(rdfs:label "positive regulation of brown fat cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of excitatory postsynaptic potential) - -AnnotationAssertion(Annotation( "GOC:BHF") "Any process that prevents the establishment or decreases the extent of the excitatory postsynaptic potential (EPSP) which is a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2010-12-15T01:43:12Z") -AnnotationAssertion( "negative regulation of excitatory post-synaptic membrane potential") -AnnotationAssertion(Annotation( "GOC:bf") "reduction of excitatory postsynaptic membrane potential") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "negative regulation of EPSP") -AnnotationAssertion( "GO:0090394") -AnnotationAssertion(rdfs:label "negative regulation of excitatory postsynaptic potential") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (organophosphate biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:chem_mtg") "The chemical reactions and pathways resulting in the biosynthesis of deoxyribose phosphate, the phosphorylated sugar 2-deoxy-erythro-pentose.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2011-02-26T02:22:41Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0090407") -AnnotationAssertion(rdfs:label "organophosphate biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (acinar cell differentiation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "The epithelial cell differentiation process in which a relatively unspecialized cell acquires specialized features of an acinar cell, a secretory cell that is grouped together with other cells of the same type to form grape-shaped clusters known as acini.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2012-05-04T09:24:48Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0090425") -AnnotationAssertion(rdfs:label "acinar cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (protein localization to nuclear envelope) - -AnnotationAssertion(Annotation( "GOC:tb") "A process in which a protein is transported to, or maintained at, a location within a nuclear envelope.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2012-07-30T01:50:41Z") -AnnotationAssertion( "protein localization in nuclear envelope") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0090435") -AnnotationAssertion(rdfs:label "protein localization to nuclear envelope") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (glutamate transmembrane import into vacuole) - -AnnotationAssertion(Annotation( "GOC:tb") "The directed movement of glutamate into the vacuole across the vacuolar membrane.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2012-09-24T14:12:46Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:tb") "vacuolar glutamate import") -AnnotationAssertion( "GO:0090454") -AnnotationAssertion(rdfs:label "glutamate transmembrane import into vacuole") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (intracellular glutamate homeostasis) - -AnnotationAssertion(Annotation( "GOC:tb") "A homeostatic process involved in the maintenance of a steady state level of glutamate within a cell.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/24220"^^xsd:anyURI) -AnnotationAssertion( "tb") -AnnotationAssertion( "2012-09-24T14:22:02Z") -AnnotationAssertion( "cellular glutamate homeostasis") -AnnotationAssertion( "glutamate homeostasis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0090461") -AnnotationAssertion(rdfs:label "intracellular glutamate homeostasis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (catecholamine uptake) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "The directed movement of catecholamine into a cell.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2012-10-17T11:06:17Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0090493") -AnnotationAssertion(rdfs:label "catecholamine uptake") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (dopamine uptake) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "The directed movement of dopamine into a cell.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2012-10-17T11:12:09Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0090494") -AnnotationAssertion(rdfs:label "dopamine uptake") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (mesenchyme migration involved in limb bud formation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "The migration of mesenchymal tissue that contributes to the formation of a limb bud.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2012-10-17T12:04:20Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0090496") -AnnotationAssertion(rdfs:label "mesenchyme migration involved in limb bud formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (mesenchymal cell migration) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "The orderly movement of a mesenchymal cell from one site to another, often during the development of a multicellular organism.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2012-10-17T12:08:17Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0090497") -AnnotationAssertion(rdfs:label "mesenchymal cell migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (L-glutamate transmembrane import into vacuole) - -AnnotationAssertion(Annotation( "GOC:al") "The directed movement of L-glutamate into the vacuole across the vacuolar membrane.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2012-12-14T11:25:52Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0090515") -AnnotationAssertion(rdfs:label "L-glutamate transmembrane import into vacuole") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (podocyte cell migration) - -AnnotationAssertion(Annotation( "GOC:pm") Annotation( "PMID:21402783") "The orderly movement of a podocyte from one site to another, often during the development of a multicellular organism or multicellular structure. A podocyte is a specialized kidney epithelial cell.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/23000"^^xsd:anyURI) -AnnotationAssertion( "tb") -AnnotationAssertion( "2013-01-08T11:08:57Z") -AnnotationAssertion( "glomerular visceral epithelial cell migration") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0090521") -AnnotationAssertion(rdfs:label "podocyte cell migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (inflammatory response to wounding) - -AnnotationAssertion(Annotation( "GOC:add") "The immediate defensive reaction by vertebrate tissue to injury caused by chemical or physical agents.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2014-08-12T12:13:53Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0090594") -AnnotationAssertion(rdfs:label "inflammatory response to wounding") -SubClassOf( ) -SubClassOf( ) - -# Class: (sensory organ morphogenesis) - -AnnotationAssertion(Annotation( "GOC:kmv") Annotation( "ISBN:978-0199210893") "Morphogenesis of a sensory organ. A sensory organ is defined as a tissue or set of tissues that work together to receive and transmit signals from external or internal stimuli. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2014-08-22T13:23:20Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0090596") -AnnotationAssertion(rdfs:label "sensory organ morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (male anatomical structure morphogenesis) - -AnnotationAssertion(Annotation( "GOC:kmv") Annotation( "GOC:tb") "The processes by which anatomical structures that are only present in the male organism are generated and organized.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2014-08-22T13:29:45Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0090598") -AnnotationAssertion(rdfs:label "male anatomical structure morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (RNA localization to nucleus) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "PMID:26305931") "A macromolecular localization process in which RNA is transported to and maintained in a location within the nucleus.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2016-07-19T17:00:49Z") -AnnotationAssertion(Annotation( "GOC:mah") "RNA localisation to nucleus") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0090685") -AnnotationAssertion(rdfs:label "RNA localization to nucleus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) # Class: (immunological memory process) @@ -110840,267 +27501,6 @@ AnnotationAssertion( "immunological memory formation process") SubClassOf( ) -# Class: (pigment granule membrane) - -AnnotationAssertion(Annotation( "PMID:11294610") "Any membrane that is part of a pigment granule.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2017-05-16T22:33:39Z") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0090741") -AnnotationAssertion(rdfs:label "pigment granule membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (acetylcholine receptor signaling pathway) - -AnnotationAssertion(Annotation( "GOC:mah") "The series of molecular signals generated as a consequence of an acetylcholine receptor binding to one of its physiological ligands.") -AnnotationAssertion( "acetylcholine receptor signalling pathway") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0095500") -AnnotationAssertion(rdfs:label "acetylcholine receptor signaling pathway") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (ceramide binding) - -AnnotationAssertion(Annotation( "GOC:sart") "Binding to a ceramide, a class of lipids composed of sphingosine linked to a fatty acid. Ceramides are a major component of cell membranes.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2011-03-09T11:34:09Z") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0097001") -AnnotationAssertion(rdfs:label "ceramide binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (ciliary plasm) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:cilia") Annotation( "GOC:dos") Annotation( "PMID:17895364") "All of the contents of a cilium, excluding the plasma membrane surrounding the cilium.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2011-03-23T01:52:31Z") -AnnotationAssertion( "cilium plasm") -AnnotationAssertion( "microtubule-based flagellar matrix") -AnnotationAssertion( "microtubule-based flagellum matrix") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "cilial cytoplasm") -AnnotationAssertion( "ciliary cytoplasm") -AnnotationAssertion( "cilium cytoplasm") -AnnotationAssertion( "microtubule-based flagellar cytoplasm") -AnnotationAssertion( "microtubule-based flagellum cytoplasm") -AnnotationAssertion( "GO:0097014") -AnnotationAssertion(rdfs:comment "Note that we deem cilium and microtubule-based flagellum to be equivalent. Also, researchers consider the composition of both the plasm and the membrane of the cilium to be detectably different from that in the non-ciliary cytosol and plasma membrane (e.g. in terms of calcium ion concentration, membrane lipid composition, and more). For this reason, the term \"ciliary plasm\" is not linked to \"cytoplasm\".") -AnnotationAssertion(rdfs:label "ciliary plasm") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (dendritic cell dendrite assembly) - -AnnotationAssertion(Annotation( "CL:0000451") Annotation( "GOC:BHF") Annotation( "PMID:12200351") "Formation of dendrites, branched cellular projections (or cytoplasmic extension) that are extended from the surface of a dendritic immune cell, and which enable the cell to sample luminal pathogens and increase the surface area for antigen presentation to T cells.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2011-03-31T04:52:53Z") -AnnotationAssertion( "dendritic extension") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0097026") -AnnotationAssertion(rdfs:comment "Note that dendrites of dendritic cells should not be confused with neuronal cell dendrites, which process electrical signals.") -AnnotationAssertion(rdfs:label "dendritic cell dendrite assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (dendritic cell differentiation) - -AnnotationAssertion(Annotation( "CL:0000451") Annotation( "GOC:pr") "The process in which a precursor cell type acquires the specialized features of a dendritic cell. A dendritic cell is a leukocyte of dendritic lineage specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2011-04-01T10:08:42Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0097028") -AnnotationAssertion(rdfs:comment "Note that immunologists typically use the word 'maturation' to refer to dendritic cells undergoing the process that GO describes as 'cell differentiation'.") -AnnotationAssertion(rdfs:label "dendritic cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (dendritic cell apoptotic process) - -AnnotationAssertion(Annotation( "CL:0000451") Annotation( "GOC:BHF") Annotation( "GOC:mtg_apoptosis") Annotation( "PMID:15059845") "Any apoptotic process in a dendritic cell, a cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2011-05-04T02:18:59Z") -AnnotationAssertion( "dendritic cell apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0097048") -AnnotationAssertion(rdfs:label "dendritic cell apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (motor neuron apoptotic process) - -AnnotationAssertion(Annotation( "CL:0000100") Annotation( "GOC:BHF") Annotation( "GOC:mtg_apoptosis") Annotation( "PMID:14523086") "Any apoptotic process in a motor neuron, an efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes movement.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2011-05-04T02:21:43Z") -AnnotationAssertion( "motoneuron apoptosis") -AnnotationAssertion( "motor neuron apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0097049") -AnnotationAssertion(rdfs:label "motor neuron apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (type B pancreatic cell apoptotic process) - -AnnotationAssertion(Annotation( "CL:0000169") Annotation( "GOC:BHF") Annotation( "GOC:mtg_apoptosis") Annotation( "PMID:16087305") "Any apoptotic process in a type B pancreatic cell, a cell located towards center of the islets of Langerhans that secretes insulin.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2011-05-04T02:24:38Z") -AnnotationAssertion( "pancreatic B cell apoptosis") -AnnotationAssertion( "pancreatic beta cell apoptosis") -AnnotationAssertion( "type B pancreatic cell apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0097050") -AnnotationAssertion(rdfs:label "type B pancreatic cell apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (L-glutamate biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:yaf") "The chemical reactions and pathways resulting in the formation of L-glutamate, the L enantiomer anion of 2-aminopentanedioic acid.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2011-05-24T04:30:38Z") -AnnotationAssertion( "L-glutamate anabolism") -AnnotationAssertion( "L-glutamate biosynthesis") -AnnotationAssertion( "L-glutamate formation") -AnnotationAssertion( "L-glutamate synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0097054") -AnnotationAssertion(rdfs:label "L-glutamate biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (synaptic membrane) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "PMID:20410104") "A specialized area of membrane on either the presynaptic or the postsynaptic side of a synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2011-06-07T11:22:09Z") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0097060") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "synaptic membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (vascular associated smooth muscle cell development) - -AnnotationAssertion(Annotation( "GOC:BHF") "The process aimed at the progression of a vascular smooth muscle cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. A vascular smooth muscle cell is a non-striated, elongated, spindle-shaped cell found lining the blood vessels.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2011-06-20T04:03:08Z") -AnnotationAssertion( "vascular smooth muscle cell development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0097084") -AnnotationAssertion(rdfs:label "vascular associated smooth muscle cell development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (craniofacial suture morphogenesis) - -AnnotationAssertion(Annotation( "GOC:pr") Annotation( "GOC:sl") Annotation( "Wikipedia:Cranial_sutures") Annotation( "Wikipedia:Head_and_neck_anatomy#Musculoskeletal_system") "The process in which any suture between cranial and/or facial bones is generated and organized.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2011-07-05T02:51:54Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0097094") -AnnotationAssertion(rdfs:label "craniofacial suture morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - -# Class: (frontonasal suture morphogenesis) - -AnnotationAssertion(Annotation( "GOC:pr") Annotation( "GOC:sl") Annotation( "PMID:12416537") Annotation( "Wikipedia:Cranial_sutures") Annotation( "Wikipedia:Head_and_neck_anatomy#Musculoskeletal_system") "The process in which the frontonasal suture, between frontal and nasal bones, is generated and organized.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2011-07-05T02:57:46Z") -AnnotationAssertion( "nasofrontal suture morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0097095") -AnnotationAssertion(rdfs:label "frontonasal suture morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (facial suture morphogenesis) - -AnnotationAssertion(Annotation( "GOC:pr") Annotation( "GOC:sl") Annotation( "Wikipedia:Cranial_sutures") Annotation( "Wikipedia:Head_and_neck_anatomy#Musculoskeletal_system") "The process in which any suture between facial bones is generated and organized.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2011-07-05T03:06:27Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0097096") -AnnotationAssertion(rdfs:label "facial suture morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (nasal suture morphogenesis) - -AnnotationAssertion(Annotation( "GOC:pr") Annotation( "GOC:sl") Annotation( "Wikipedia:Cranial_sutures") Annotation( "Wikipedia:Head_and_neck_anatomy#Musculoskeletal_system") "The process in which the nasal suture is generated and organized.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2011-07-05T03:09:04Z") -AnnotationAssertion( "internasal suture morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0097097") -AnnotationAssertion(rdfs:label "nasal suture morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (postsynaptic membrane assembly) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:sjp") Annotation( "PMID:21424692") "The aggregation, arrangement and bonding together of a set of components to form a postsynaptic membrane, a specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft).") -AnnotationAssertion( "pr") -AnnotationAssertion( "2011-07-27T01:26:49Z") -AnnotationAssertion( "post-synaptic membrane assembly") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0097104") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "postsynaptic membrane assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (receptor localization to synapse) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:sjp") Annotation( "PMID:21525273") "Any process in which a receptor is transported to, and/or maintained at the synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2011-07-31T09:20:30Z") -AnnotationAssertion( "receptor localisation to synapse") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0097120") -AnnotationAssertion(rdfs:label "receptor localization to synapse") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (mesenchymal cell apoptotic process) - -AnnotationAssertion(Annotation( "CL:0000134") Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:yaf") Annotation( "PMID:18231833") "Any apoptotic process in a mesenchymal cell. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2011-09-06T02:31:59Z") -AnnotationAssertion( "mesenchymal cell apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0097152") -AnnotationAssertion(rdfs:label "mesenchymal cell apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (GABAergic neuron differentiation) - -AnnotationAssertion(Annotation( "GOC:kmv") Annotation( "PMID:11517269") "The process in which a neuroblast acquires the specialized structural and functional features of a GABAergic neuron.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2011-09-14T09:39:11Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0097154") -AnnotationAssertion(rdfs:label "GABAergic neuron differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (organic cyclic compound binding) - -AnnotationAssertion(Annotation( "GOC:sjw") Annotation( "PMID:7583672") "Binding to an organic cyclic compound, any molecular entity that contains carbon arranged in a cyclic molecular structure.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2011-09-23T02:31:01Z") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0097159") -AnnotationAssertion(rdfs:label "organic cyclic compound binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (ammonium ion metabolic process) AnnotationAssertion(Annotation( "GOC:dhl") Annotation( "GOC:tb") Annotation( "PMID:14671018") "The chemical reactions and pathways involving the ammonium ion.") @@ -111111,7 +27511,6 @@ AnnotationAssertion( "ammonium metabolic process") AnnotationAssertion( "GO:0097164") AnnotationAssertion(rdfs:label "ammonium ion metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) # Class: (amelogenesis) @@ -111123,51 +27522,8 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0097186") AnnotationAssertion(rdfs:label "amelogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (dentinogenesis) - -AnnotationAssertion(Annotation( "GOC:cjm") Annotation( "GOC:sl") Annotation( "PMID:10206335") Annotation( "PMID:21196346") "The process whose specific outcome is the formation of dentin, the mineralized tissue that constitutes the major bulk of teeth. Dentin may be one of three types: primary dentin, secondary dentin, and tertiary dentin.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2011-11-21T09:04:17Z") -AnnotationAssertion( "dentin development") -AnnotationAssertion( "dentine development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0097187") -AnnotationAssertion(rdfs:label "dentinogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (apoptotic signaling pathway) - -AnnotationAssertion(Annotation( "GOC:mtg_apoptosis") "The series of molecular signals which triggers the apoptotic death of a cell. The pathway starts with reception of a signal, and ends when the execution phase of apoptosis is triggered.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2011-11-23T09:30:23Z") -AnnotationAssertion( "GO:0008624") -AnnotationAssertion(Annotation( "GOC:mah") "apoptotic signalling pathway") -AnnotationAssertion( "induction of apoptosis by extracellular signals") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0097190") -AnnotationAssertion(rdfs:comment "This term can be used to annotate gene products involved in apoptotic events happening downstream of the cross-talk point between the extrinsic and intrinsic apoptotic pathways. The cross-talk starts when caspase-8 cleaves Bid and truncated Bid interacts with mitochondria. From this point on it is not possible to distinguish between extrinsic and intrinsic pathways.") -AnnotationAssertion(rdfs:label "apoptotic signaling pathway") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (execution phase of apoptosis) - -AnnotationAssertion(Annotation( "GOC:mtg_apoptosis") Annotation( "PMID:21760595") "A stage of the apoptotic process that starts with the controlled breakdown of the cell through the action of effector caspases or other effector molecules (e.g. cathepsins, calpains etc.). Key steps of the execution phase are rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2011-11-23T09:45:24Z") -AnnotationAssertion( "execution phase of apoptotic process") -AnnotationAssertion( "apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0097194") -AnnotationAssertion(rdfs:label "execution phase of apoptosis") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (renal filtration) AnnotationAssertion(Annotation( "GOC:pr") Annotation( "GOC:sart") "A renal system process in which fluid circulating through the body is filtered through a barrier system.") @@ -111178,41 +27534,6 @@ AnnotationAssertion( "renal filtration") SubClassOf( ) -# Class: (lysosomal membrane organization) - -AnnotationAssertion(Annotation( "GOC:yaf") Annotation( "PMID:20544854") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lysosomal membrane. A lysosomal membrane is the lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2012-01-12T10:16:15Z") -AnnotationAssertion(Annotation( "GOC:mah") "lysosomal membrane organisation") -AnnotationAssertion( "lysosome membrane organization") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0097212") -AnnotationAssertion(rdfs:label "lysosomal membrane organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cellular response to toxic substance) - -AnnotationAssertion(Annotation( "GOC:pr") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toxic stimulus.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2012-02-02T12:23:31Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0097237") -AnnotationAssertion(rdfs:label "cellular response to toxic substance") - -# Class: (oligodendrocyte apoptotic process) - -AnnotationAssertion(Annotation( "CL:0000128") Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:yaf") Annotation( "PMID:16723520") "Any apoptotic process in an oligodendrocyte. Oligodendrocytes belong to a class of large neuroglial (macroglial) cells in the central nervous system, where they form the insulating myelin sheath of axons.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2012-03-05T10:51:15Z") -AnnotationAssertion( "oligodendrocyte apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0097252") -AnnotationAssertion(rdfs:label "oligodendrocyte apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - # Class: (renal tubular secretion) AnnotationAssertion(Annotation( "GOC:rph") Annotation( "PMID:25287933") Annotation( "Wikipedia:Renal_secretion#Secretion") "The elimination of substances from peritubular capillaries (or surrounding hemolymph in invertebrates) into the renal tubules to be incorporated subsequently into the urine. Substances that are secreted include organic anions, ammonia, potassium and drugs.") @@ -111225,124 +27546,6 @@ AnnotationAssertion(rdfs:label "rena SubClassOf( ) SubClassOf( ) -# Class: (ammonium homeostasis) - -AnnotationAssertion(Annotation( "GOC:yaf") Annotation( "PMID:12695560") "Any biological process involved in the maintenance of an internal steady state of ammonium.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2012-03-22T02:51:22Z") -AnnotationAssertion( "ammonia homeostasis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0097272") -AnnotationAssertion(rdfs:label "ammonium homeostasis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (intracellular ammonium homeostasis) - -AnnotationAssertion(Annotation( "GOC:yaf") Annotation( "PMID:12695560") "A homeostatic process involved in the maintenance of a steady state level of ammonium within a cell.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2012-03-22T02:54:38Z") -AnnotationAssertion( "cellular ammonia homeostasis") -AnnotationAssertion( "cellular ammonium homeostasis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0097275") -AnnotationAssertion(rdfs:label "intracellular ammonium homeostasis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (keratinocyte apoptotic process) - -AnnotationAssertion(Annotation( "CL:0000312") Annotation( "GOC:jc") Annotation( "GOC:mtg_apoptosis") Annotation( "PMID:10201527") "Any apoptotic process in a keratinocyte. A keratinocyte is an epidermal cell which synthesizes keratin and undergoes a characteristic change as it moves upward from the basal layers of the epidermis to the cornified (horny) layer of the skin.") -AnnotationAssertion( ) -AnnotationAssertion( "pr") -AnnotationAssertion( "2012-03-29T10:20:51Z") -AnnotationAssertion( "keratinocyte apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0097283") -AnnotationAssertion(rdfs:label "keratinocyte apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) -DisjointClasses( ObjectSomeValuesFrom( )) - -# Class: (hepatocyte apoptotic process) - -AnnotationAssertion(Annotation( "CL:0000182") Annotation( "GOC:jc") Annotation( "GOC:mtg_apoptosis") Annotation( "PMID:15856020") "Any apoptotic process in a hepatocyte, the main structural component of the liver.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2012-03-29T10:23:21Z") -AnnotationAssertion( "hepatocyte apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0097284") -AnnotationAssertion(rdfs:label "hepatocyte apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (response to alcohol) - -AnnotationAssertion(Annotation( "GOC:pr") Annotation( "PMID:24014527") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alcohol stimulus.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2012-05-15T03:48:45Z") -AnnotationAssertion( "GO:1990335") -AnnotationAssertion( "process resulting in tolerance to alcohol") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0097305") -AnnotationAssertion(rdfs:label "response to alcohol") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cellular response to alcohol) - -AnnotationAssertion(Annotation( "GOC:pr") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alcohol stimulus.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2012-05-15T03:49:51Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0097306") -AnnotationAssertion(rdfs:label "cellular response to alcohol") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (melanocyte migration) - -AnnotationAssertion(Annotation( "CL:0000148") Annotation( "GOC:uh") Annotation( "PMID:22637532") "The orderly movement of melanocytes from one site to another, often during the development of a multicellular organism. A melanocyte is a pigment cell derived from the neural crest. It contains melanin-filled pigment granules, which give a brown to black appearance.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2012-06-08T10:08:18Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0097324") -AnnotationAssertion(rdfs:label "melanocyte migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (protein localization to heterochromatin) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process in which a protein is transported to, or maintained at, a part of a chromosome that is organized into heterochromatin.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2012-07-03T03:19:07Z") -AnnotationAssertion(Annotation( "GOC:mah") "protein localisation to heterochromatin") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0097355") -AnnotationAssertion(rdfs:label "protein localization to heterochromatin") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (chorionic trophoblast cell proliferation) - -AnnotationAssertion(Annotation( "CL:0011101") Annotation( "GOC:BHF") Annotation( "PMID:15150278") "The multiplication or reproduction of chorionic trophoblast cells, resulting in the expansion of their population.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2012-07-19T10:17:37Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0097360") -AnnotationAssertion(rdfs:label "chorionic trophoblast cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (carbohydrate derivative binding) - -AnnotationAssertion(Annotation( "GOC:pr") "Binding to a carbohydrate derivative.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2012-08-02T13:03:39Z") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0097367") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "carbohydrate derivative binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - # Class: (glial cell projection) AnnotationAssertion(Annotation( "GOC:mc") "A prolongation or process extending from a glial cell.") @@ -111353,72 +27556,6 @@ AnnotationAssertion( "glial projection") AnnotationAssertion( "GO:0097386") AnnotationAssertion(rdfs:label "glial cell projection") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (neuroblast migration) - -AnnotationAssertion(Annotation( "CL:0000031") Annotation( "GOC:jc") Annotation( "PMID:15543145") "The orderly movement of a neuroblast from one site to another, often during the development of a multicellular organism or multicellular structure. A neuroblast is any cell that will divide and give rise to a neuron.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2012-10-29T08:24:37Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0097402") -AnnotationAssertion(rdfs:label "neuroblast migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (hippocampal interneuron differentiation) - -AnnotationAssertion(Annotation( "CL:1001569") Annotation( "GOC:jc") Annotation( "PMID:19655320") "The process in which a relatively unspecialized cell acquires specialized features of a hippocampal interneuron.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2012-11-04T10:58:28Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0097410") -AnnotationAssertion(rdfs:label "hippocampal interneuron differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (microtubule bundle) - -AnnotationAssertion(Annotation( "NIF_Subcellular:sao1872343973") "An arrangement of closely apposed microtubules running parallel to each other.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2012-11-07T15:01:27Z") -AnnotationAssertion( "NIF_Subcellular:sao1872343973") -AnnotationAssertion( "microtubule fascicle") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0097427") -AnnotationAssertion(rdfs:label "microtubule bundle") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (hippocampal pyramidal neuron differentiation) - -AnnotationAssertion(Annotation( "CL:1001571") Annotation( "GOC:jc") Annotation( "PMID:19342486") "The process in which a relatively unspecialized cell acquires specialized features of a hippocampal pyramidal neuron, a pyramidal cell of the hippocampus.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2012-11-22T09:33:31Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0097432") -AnnotationAssertion(rdfs:label "hippocampal pyramidal neuron differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (supramolecular fiber organization) - -AnnotationAssertion(Annotation( "GOC:pr") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a supramolecular fiber, a polymer consisting of an indefinite number of protein or protein complex subunits that have polymerised to form a fiber-shaped structure.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2012-11-27T15:46:25Z") -AnnotationAssertion( "GO:0043206") -AnnotationAssertion( "extracellular fibril organisation") -AnnotationAssertion( "extracellular fibril organization") -AnnotationAssertion(Annotation( "GOC:mah") "extracellular fibril organization and biogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "fibril organisation") -AnnotationAssertion( "fibril organization") -AnnotationAssertion( "GO:0097435") -AnnotationAssertion(rdfs:label "supramolecular fiber organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) # Class: (dendritic tree) @@ -111445,7 +27582,6 @@ AnnotationAssertion(Annotation( "NIF_Subcellular:sao1189060993") "vellous process") AnnotationAssertion( "GO:0097449") AnnotationAssertion(rdfs:label "astrocyte projection") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) # Class: (astrocyte end-foot) @@ -111460,224 +27596,19 @@ AnnotationAssertion( "astrocyte end-foot") SubClassOf( ) -# Class: (Schwann cell microvillus) - -AnnotationAssertion(Annotation( "NIF_Subcellular:sao1890444066") Annotation( "PMID:15988042") "Small finger-like extension of a Schwann cell that contacts the nodal membrane.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2012-12-19T13:01:02Z") -AnnotationAssertion( "NIF_Subcellular:sao1890444066") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0097454") -AnnotationAssertion(rdfs:label "Schwann cell microvillus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - # Class: (hippocampal mossy fiber) -AnnotationAssertion(Annotation( "NIF_Subcellular:nlx_subcell_100312") Annotation( "PMID:17765709") "Axon of dentate gyrus granule cell projecting to hippocampal area CA3, characterized by expansions (mossy fiber expansions) giving the fibers a mossy appearance. These unmyelinated axons were first described by Ramon y Cajal.") +AnnotationAssertion(Annotation( "NIF_Subcellular:nlx_subcell_100312") Annotation( "PMID:17765709") Annotation( "PMID:20554881") Annotation( "PMID:24336151") "An axon of a hippocampal granule cell, including dentate gyrus granule cell and CA3 granule cell, characterized by expansions (mossy fiber expansions) giving the fibers a mossy appearance. These unmyelinated axons were first described by Ramon y Cajal.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/25796"^^xsd:anyURI) AnnotationAssertion( "pr") AnnotationAssertion( "2012-12-19T16:51:57Z") AnnotationAssertion( "NIF_Subcellular:nlx_subcell_100312") AnnotationAssertion( "cellular_component") AnnotationAssertion( "GO:0097457") AnnotationAssertion(rdfs:label "hippocampal mossy fiber") -SubClassOf( ) +SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (retinal rod cell apoptotic process) - -AnnotationAssertion(Annotation( "CL:0000604") Annotation( "GOC:jc") Annotation( "PMID:17202487") "Any apoptotic process in a retinal rod cell, one of the two photoreceptor cell types of the vertebrate retina.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2013-03-21T09:44:45Z") -AnnotationAssertion( "rod photoreceptor apoptotic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0097473") -AnnotationAssertion(rdfs:label "retinal rod cell apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (retinal cone cell apoptotic process) - -AnnotationAssertion(Annotation( "CL:0000573") Annotation( "GOC:jc") "Any apoptotic process in a retinal cone cell, one of the two photoreceptor cell types of the vertebrate retina.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2013-03-21T09:46:22Z") -AnnotationAssertion( "cone photoreceptor apoptotic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0097474") -AnnotationAssertion(rdfs:label "retinal cone cell apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (motor neuron migration) - -AnnotationAssertion(Annotation( "CL:0000100") Annotation( "GOC:yaf") Annotation( "PMID:20711475") "The orderly movement of a motor neuron from one site to another. A motor neuron is an efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes movement.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2013-04-23T13:00:46Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0097475") -AnnotationAssertion(rdfs:label "motor neuron migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (spinal cord motor neuron migration) - -AnnotationAssertion(Annotation( "CL:0011001") Annotation( "GOC:yaf") Annotation( "PMID:20711475") "The orderly movement of a spinal cord motor neuron from one site to another. A spinal cord motor neuron is a motor neuron that passes from the spinal cord toward or to a muscle and conducts an impulse that causes movement.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2013-04-23T13:03:46Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0097476") -AnnotationAssertion(rdfs:label "spinal cord motor neuron migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (protein localization to non-motile cilium) - -AnnotationAssertion(Annotation( "GOC:cilia") Annotation( "GOC:kmv") Annotation( "PMID:23128241") "A process in which a protein is transported to, or maintained in, a location within a non-motile cilium.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2013-08-13T12:16:26Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "protein localization to nonmotile primary cilium") -AnnotationAssertion( "GO:0097499") -AnnotationAssertion(rdfs:label "protein localization to non-motile cilium") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (dendritic cell dendrite) - -AnnotationAssertion(Annotation( "CL:0000451") Annotation( "GOC:BHF") Annotation( "GOC:cjm") Annotation( "PMID:12200351") "A branched cellular projection (or cytoplasmic extension) that is extended from the surface of a dendritic immune cell, and which enables the cell to sample luminal pathogens and increase the surface area for antigen presentation to T cells.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2013-10-16T13:02:25Z") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0097511") -AnnotationAssertion(rdfs:label "dendritic cell dendrite") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cardiac myofibril) - -AnnotationAssertion(Annotation( "GOC:cjm") Annotation( "GOC:devbiol") "A cardiac myofibril is a myofibril specific to cardiac muscle cells.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2013-10-16T13:04:58Z") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0097512") -AnnotationAssertion(rdfs:label "cardiac myofibril") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (sperm plasma membrane) - -AnnotationAssertion(Annotation( "GOC:cjm") "A plasma membrane that is part of a sperm cell.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2013-10-18T11:31:17Z") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0097524") -AnnotationAssertion(rdfs:label "sperm plasma membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (myeloid leukocyte migration) - -AnnotationAssertion(Annotation( "GOC:cvs") Annotation( "PMID:22342843") Annotation( "PMID:24157461") "The movement of a myeloid leukocyte within or between different tissues and organs of the body.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2013-11-11T13:59:43Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0097529") -AnnotationAssertion(rdfs:label "myeloid leukocyte migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (granulocyte migration) - -AnnotationAssertion(Annotation( "GOC:cvs") Annotation( "PMID:24163421") Annotation( "PMID:24193336") "The movement of a granulocyte within or between different tissues and organs of the body.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2013-11-11T14:00:44Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0097530") -AnnotationAssertion(rdfs:label "granulocyte migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (lymphoid lineage cell migration) - -AnnotationAssertion(Annotation( "GOC:pr") Annotation( "PMID:22342843") "The orderly movement of a lymphoid lineage cell from one site to another. A lymphoid lineage cell, also called a lymphoid lineage restricted progenitor cell, is a progenitor cell restricted to the lymphoid lineage.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2013-11-28T10:47:15Z") -AnnotationAssertion( "lymphoid lineage restricted progenitor cell migration") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0097534") -AnnotationAssertion(rdfs:label "lymphoid lineage cell migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (thymus epithelium morphogenesis) - -AnnotationAssertion(Annotation( "GOC:pr") Annotation( "PMID:22342843") "The process in which the thymus epithelium is generated and organized.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2013-11-28T10:51:03Z") -AnnotationAssertion( "thymic epithelium morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0097536") -AnnotationAssertion(rdfs:label "thymus epithelium morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (calcium ion transmembrane import into cytosol) - -AnnotationAssertion(Annotation( "GOC:vw") "A process in which a calcium ion is transported from one side of a membrane to the other into the cytosol by means of some agent such as a transporter or pore.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/23015"^^xsd:anyURI) -AnnotationAssertion( "pr") -AnnotationAssertion( "2014-01-23T11:05:13Z") -AnnotationAssertion( "GO:0060401") -AnnotationAssertion( "calcium transmembrane import into cytosol") -AnnotationAssertion( "cytosolic calcium ion transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0097553") -AnnotationAssertion(rdfs:label "calcium ion transmembrane import into cytosol") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (vacuole fusion) - -AnnotationAssertion(Annotation( "GOC:pr") Annotation( "GOC:vw") Annotation( "Wikipedia:Vacuole") "Merging of two or more vacuoles, or of vacuoles and vesicles within a cell to form a single larger vacuole.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2014-02-28T09:49:31Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0097576") -AnnotationAssertion(rdfs:label "vacuole fusion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (calcitonin family receptor activity) - -AnnotationAssertion(Annotation( "GOC:bhm") Annotation( "InterPro:IPR003287") Annotation( "PMID:10871296") Annotation( "PMID:12037140") Annotation( "PMID:18687416") "Combining with any member of the calcitonin family (e.g. adrenomedullin, adrenomedullin 2 (intermedin), amylin, calcitonin and calcitonin gene-related peptides (CGRPs)) to initiate a change in cell activity.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2014-09-08T15:32:19Z") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0097642") -AnnotationAssertion(rdfs:label "calcitonin family receptor activity") -SubClassOf( ) - -# Class: (calcitonin family binding) - -AnnotationAssertion(Annotation( "GOC:bhm") Annotation( "InterPro:IPR021116") Annotation( "PMID:10871296") Annotation( "PMID:12037140") Annotation( "PMID:18687416") "Binding to a member of the calcitonin family (e.g. adrenomedullin, adrenomedullin 2 (intermedin), amylin, calcitonin and calcitonin gene-related peptides (CGRPs)).") -AnnotationAssertion( "pr") -AnnotationAssertion( "2014-09-08T20:50:52Z") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0097644") -AnnotationAssertion(rdfs:label "calcitonin family binding") -SubClassOf( ) - -# Class: (G protein-coupled receptor complex) - -AnnotationAssertion(Annotation( "GOC:bhm") "A protein complex that contains G protein-coupled receptors.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2014-09-10T09:14:30Z") -AnnotationAssertion( "G-protein coupled receptor complex") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0097648") -AnnotationAssertion(rdfs:label "G protein-coupled receptor complex") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (intracellular vesicle) AnnotationAssertion(Annotation( "GOC:vesicles") "Any vesicle that is part of the intracellular region.") @@ -111686,62 +27617,9 @@ AnnotationAssertion( AnnotationAssertion( "cellular_component") AnnotationAssertion( "GO:0097708") AnnotationAssertion(rdfs:label "intracellular vesicle") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (ciliary basal body-plasma membrane docking) - -AnnotationAssertion(Annotation( "GOC:cilia") Annotation( "PMID:13978319") Annotation( "PMID:23348840") Annotation( "PMID:23530209") Annotation( "PMID:25686250") Annotation( "PMID:26981235") Annotation( "Reactome:R-HSA-5620912.1") "The docking of a cytosolic centriole/basal body to the plasma membrane via the ciliary transition fibers. In some species this may happen via an intermediate step, by first docking to the ciliary vesicle via the ciliary transition fibers. The basal body-ciliary vesicle then relocates to the plasma membrane, followed by the ciliary vesicle fusing with the plasma membrane, effectively attaching the basal body to the plasma membrane.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2016-08-05T16:12:33Z") -AnnotationAssertion( "Reactome:R-HSA-5620912.1") -AnnotationAssertion( "ciliary basal body docking") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "anchoring of the basal body to the plasma membrane") -AnnotationAssertion( "GO:0097711") -AnnotationAssertion(rdfs:comment "Basal bodies in jawed vertebrates appear to first attach to a ciliary vesicle. It is unclear how specific this is to jawed vertebrates or if other organisms also employ this sequence. Some species like Giardia intestinalis do not relocate their basal bodies to the plasma membrane, but have their axonemes extend through the cytosol to then protrude out of the cell to form flagella.") -AnnotationAssertion(rdfs:label "ciliary basal body-plasma membrane docking") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (vesicle targeting, trans-Golgi to periciliary membrane compartment) - -AnnotationAssertion(Annotation( "GOC:cilia") Annotation( "PMID:20106869") Annotation( "PMID:23351793") Annotation( "PMID:24814148") Annotation( "PMID:26485645") Annotation( "Reactome:R-HSA-5620920.1") "The process in which vesicles formed at the trans-Golgi network are directed to the plasma membrane surrounding the base of the cilium, including the ciliary pocket, mediated by molecules at the vesicle membrane and target membrane surfaces.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2016-08-05T16:16:28Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0097712") -AnnotationAssertion(rdfs:label "vesicle targeting, trans-Golgi to periciliary membrane compartment") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (neural tissue regeneration) - -AnnotationAssertion(Annotation( "Wikipedia:Neuroregeneration") "The regrowth of neural tissue following its loss or destruction.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2016-08-25T13:14:27Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "neuroregeneration") -AnnotationAssertion( "GO:0097719") -AnnotationAssertion(rdfs:label "neural tissue regeneration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (sperm motility) - -AnnotationAssertion(Annotation( "GOC:cilia") Annotation( "GOC:krc") "Any process involved in the controlled movement of a sperm cell.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2016-09-01T12:00:45Z") -AnnotationAssertion( "sperm movement") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0097722") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "sperm motility") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - # Class: (non-motile cilium) AnnotationAssertion(Annotation( "GOC:cilia") Annotation( "GOC:dgh") Annotation( "GOC:kmv") Annotation( "PMID:17009929") Annotation( "PMID:20144998") Annotation( "PMID:22118931") "A cilium which may have a variable array of axonemal microtubules but does not contain molecular motors.") @@ -111786,105 +27664,6 @@ SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (extracellular exosome biogenesis) - -AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:bf") Annotation( "PMID:19442504") Annotation( "PMID:25392495") "The assembly and secretion of an extracellular exosome, a membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2016-10-03T14:35:25Z") -AnnotationAssertion( "exosome assembly or secretion") -AnnotationAssertion( "exosome biogenesis") -AnnotationAssertion( "exosome production") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "ILV assembly") -AnnotationAssertion( "intraluminal vesicle assembly") -AnnotationAssertion( "GO:0097734") -AnnotationAssertion(rdfs:label "extracellular exosome biogenesis") -SubClassOf( ) - -# Class: (excitatory neuromuscular junction) - -AnnotationAssertion(Annotation( "GOC:dos") "The junction between the axon of a motor neuron and a muscle fiber. In response to the arrival of action potentials, the presynaptic button releases molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane of the muscle fiber, leading to a post-synaptic potential responsible for muscle contraction.") -AnnotationAssertion( "dos") -AnnotationAssertion( "2013-10-14T12:02:51Z") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0098520") -AnnotationAssertion(rdfs:label "excitatory neuromuscular junction") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (neuromuscular junction of skeletal muscle fiber) - -AnnotationAssertion(Annotation( "GOC:dos") "A neuromuscular junction in which the target muscle cell is a skeletal muscle fiber.") -AnnotationAssertion( "dos") -AnnotationAssertion( "2013-10-14T12:04:32Z") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0098522") -AnnotationAssertion(rdfs:comment "In vertebrates, the term 'neuromuscular junction' is limited to synapses targeting skeletal muscle fibers - all of which are cholinergic and excitatory. Both inhibitory and excitatory neuromuscular junctions exist in invertebrates, utilizing a range of neurotransmitters including glutamate, GABA and 5-HT.") -AnnotationAssertion(rdfs:label "neuromuscular junction of skeletal muscle fiber") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (neuromuscular junction of myotube) - -AnnotationAssertion(Annotation( "GOC:dos") "A neuromuscular junction in which the target muscle cell is a myotube.") -AnnotationAssertion( "dos") -AnnotationAssertion( "2013-10-14T12:05:12Z") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0098523") -AnnotationAssertion(rdfs:comment "In vertebrates, the term 'neuromuscular junction' is limited to synapses targeting the myotubes of skeletal muscle (AKA skeletal muscle fibers). Neuromuscular junctions targeting other muscle cell types exist in invertebrates such as the mononucleate somatic muscles of nematodes.") -AnnotationAssertion(rdfs:label "neuromuscular junction of myotube") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (neuromuscular junction of somatic muscle myotube) - -AnnotationAssertion(Annotation( "GOC:dos") "A neuromuscular junction in which the target muscle cell is a somatic muscle myotube, such as an arthropod somatic muscle cell.") -AnnotationAssertion( "dos") -AnnotationAssertion( "2013-10-14T12:05:43Z") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0098524") -AnnotationAssertion(rdfs:label "neuromuscular junction of somatic muscle myotube") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (excitatory neuromuscular junction of somatic myotube) - -AnnotationAssertion(Annotation( "GOC:dos") "A neuromuscular junction that functions in the excitation of somatic muscle myotubes, such as an arthropod somatic muscle cells.") -AnnotationAssertion( "dos") -AnnotationAssertion( "2013-10-14T12:06:08Z") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0098525") -AnnotationAssertion(rdfs:label "excitatory neuromuscular junction of somatic myotube") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (neuromuscular junction of somatic muscle) - -AnnotationAssertion(Annotation( "GOC:dos") "A neuromuscular junction in which the target muscle cell is a somatic muscle cell, such as those found in nematodes and arthropods.") -AnnotationAssertion( "dos") -AnnotationAssertion( "2013-10-14T12:07:05Z") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0098527") -AnnotationAssertion(rdfs:label "neuromuscular junction of somatic muscle") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (skeletal muscle fiber differentiation) - -AnnotationAssertion(Annotation( "GOC:dos") "The process in which a relatively unspecialized cell acquires specialized features of a skeletal muscle fiber cell. Skeletal muscle fiber differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual skeletal muscle fibers fuse to form bigger myotubes and start to contract.") -AnnotationAssertion( "dos") -AnnotationAssertion( "2013-10-15T14:00:34Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0098528") -AnnotationAssertion(rdfs:label "skeletal muscle fiber differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (neuromuscular junction development, skeletal muscle fiber) - -AnnotationAssertion(Annotation( "GOC:mtg_OBO2OWL_2013") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a neuromuscular junction that targets a skeletal muscle fiber.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0098529") -AnnotationAssertion(rdfs:label "neuromuscular junction development, skeletal muscle fiber") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (defense response to other organism) AnnotationAssertion(Annotation( "GOC:dos") "Reactions triggered in response to the presence of another organism that act to protect the cell or organism from damage caused by that organism.") @@ -111901,30 +27680,8 @@ AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "defense response to other organism") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (maintenance of protein complex location) - -AnnotationAssertion(Annotation( "GOC:dos") "Any process in which a protein complex is maintained in a location and prevented from moving elsewhere. These include sequestration, stabilization to prevent transport elsewhere and the active retrieval of protein complexes that move away.") -AnnotationAssertion( "dos") -AnnotationAssertion( "2013-11-15T18:20:16Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0098544") -AnnotationAssertion(rdfs:label "maintenance of protein complex location") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (maintenance of protein complex location in cytoplasm) - -AnnotationAssertion(Annotation( "GOC:dos") "Any process in which a protein complex is maintained in a specific location within the cytoplasm and is prevented from moving elsewhere.") -AnnotationAssertion( "dos") -AnnotationAssertion( "2013-11-15T20:49:15Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0098545") -AnnotationAssertion(rdfs:label "maintenance of protein complex location in cytoplasm") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - # Class: (learned vocalization behavior) AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dos") Annotation( "GOC:rl") Annotation( "PMID:16418265") Annotation( "PMID:17035521") "A vocalization behavior that is the result of learning.") @@ -111937,31 +27694,6 @@ AnnotationAssertion(rdfs:label "lear SubClassOf( ) SubClassOf( ) -# Class: (bounding membrane of organelle) - -AnnotationAssertion(Annotation( "GOC:dos") "The lipid bilayer that forms the outer-most layer of an organelle.") -AnnotationAssertion( "dos") -AnnotationAssertion( "2014-02-26T13:41:31Z") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0098588") -AnnotationAssertion(rdfs:comment "Examples include the outer membranes of double membrane bound organelles such as mitochondria as well as the bounding membranes of single-membrane bound organelles such as lysosomes.") -AnnotationAssertion(rdfs:label "bounding membrane of organelle") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (plasma membrane region) - -AnnotationAssertion(Annotation( "GOC:dos") "A membrane that is a (regional) part of the plasma membrane.") -AnnotationAssertion( "dos") -AnnotationAssertion( "2014-03-06T11:55:32Z") -AnnotationAssertion( "region of plasma membrane") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0098590") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "Note that this term should not be used for direct manual annotation as it should always be possible to choose a more specific subclass.") -AnnotationAssertion(rdfs:label "plasma membrane region") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (learned vocalization behavior or vocal learning) AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dos") Annotation( "GOC:rl") Annotation( "PMID:16418265") Annotation( "PMID:17035521") "Vocalisation behavior that is the result of learning, or the process by which new vocalizations are learned.") @@ -111973,85 +27705,12 @@ AnnotationAssertion(rdfs:comment "Th AnnotationAssertion(rdfs:label "learned vocalization behavior or vocal learning") SubClassOf( ) -# Class: (cell-cell adhesion) - -AnnotationAssertion(Annotation( "GOC:dos") "The attachment of one cell to another cell via adhesion molecules.") -AnnotationAssertion( "dos") -AnnotationAssertion( "2014-04-16T13:40:03Z") -AnnotationAssertion( "GO:0016337") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "single organismal cell-cell adhesion") -AnnotationAssertion( "GO:0098609") -AnnotationAssertion(rdfs:label "cell-cell adhesion") -SubClassOf( ) - -# Class: (cell adhesion mediator activity) - -AnnotationAssertion(Annotation( "GOC:vw") Annotation( "Wikipedia:Cell_adhesion") "The binding by a cell-adhesion protein on a cell surface to an adhesion molecule on another cell surface or an external substrate, to mediate adhesion of the cell to the external substrate or to another cell.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/22959"^^xsd:anyURI) -AnnotationAssertion( "cell adhesion molecule") -AnnotationAssertion( "protein binding involved in cell adhesion") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0098631") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "cell adhesion mediator activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (cell-cell adhesion mediator activity) - -AnnotationAssertion(Annotation( "Wikipedia:Cell_adhesion") "The binding by a cell-adhesion protein on the cell surface to an extracellular matrix component, to mediate adhesion of the cell to another cell.") -AnnotationAssertion( "cell-cell adhesion molecule") -AnnotationAssertion( "protein binding involved in cell-cell adhesion") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0098632") -AnnotationAssertion(rdfs:label "cell-cell adhesion mediator activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (collagen fibril binding) - -AnnotationAssertion(Annotation( "GOC:dos") Annotation( "PMID:21421911") "Binding to a collagen fibril.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0098633") -AnnotationAssertion(rdfs:label "collagen fibril binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (protein complex involved in cell-cell adhesion) - -AnnotationAssertion(Annotation( "GOC:dos") "Any protein complex that is capable of carrying out some part of the process of cell-cell adhesion.") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0098635") -AnnotationAssertion(rdfs:label "protein complex involved in cell-cell adhesion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (protein complex involved in cell adhesion) - -AnnotationAssertion(Annotation( "GOC:dos") "Any protein complex that is capable of carrying out some part of the process of cell adhesion to the cell matrix or to another cell.") -AnnotationAssertion( "GO:1990307") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "cell adhesion complex") -AnnotationAssertion( "GO:0098636") -AnnotationAssertion(rdfs:label "protein complex involved in cell adhesion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cadherin binding involved in cell-cell adhesion) - -AnnotationAssertion(Annotation( "GOC:dos") "Any cadherin binding that occurs as part of the process of cell-cell adhesion.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0098641") -AnnotationAssertion(rdfs:label "cadherin binding involved in cell-cell adhesion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (network-forming collagen trimer) AnnotationAssertion(Annotation( "PMID:21421911") "A collagen trimer that forms networks.") AnnotationAssertion( "cellular_component") AnnotationAssertion( "GO:0098642") AnnotationAssertion(rdfs:label "network-forming collagen trimer") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) @@ -112093,306 +27752,9 @@ AnnotationAssertion(Annotation( "cellular_component") AnnotationAssertion( "GO:0098651") AnnotationAssertion(rdfs:label "basement membrane collagen trimer") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (monoatomic cation transmembrane transport) - -AnnotationAssertion(Annotation( "GOC:dos") Annotation( "GOC:vw") "The process in which a monoatomic cation is transported across a membrane. Monatomic cations (also called simple cations) are positively charged ions consisting of exactly one atom.") -AnnotationAssertion( "GO:0099132") -AnnotationAssertion( "cation transmembrane transport") -AnnotationAssertion( "ATP hydrolysis coupled cation transmembrane transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0098655") -AnnotationAssertion(rdfs:label "monoatomic cation transmembrane transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (import into cell) - -AnnotationAssertion(Annotation( "GOC:dos") "The directed movement of some substance from outside of a cell into a cell. This may occur via transport across the plasma membrane or via endocytosis.") -AnnotationAssertion( "uptake") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0098657") -AnnotationAssertion(rdfs:label "import into cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (inorganic anion import across plasma membrane) - -AnnotationAssertion(Annotation( "GOC:dos") "The directed movement of inorganic anions from outside of a cell, across the plasma membrane and into the cytosol.") -AnnotationAssertion( "inorganic anion import into cell") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0098658") -AnnotationAssertion(rdfs:label "inorganic anion import across plasma membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (inorganic cation import across plasma membrane) - -AnnotationAssertion(Annotation( "GOC:dos") "The directed movement of inorganic cations from outside of a cell, across the plasma membrane and into the cytosol.") -AnnotationAssertion( "inorganic cation import into cell") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0098659") -AnnotationAssertion(rdfs:label "inorganic cation import across plasma membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (inorganic ion transmembrane transport) - -AnnotationAssertion(Annotation( "GOC:mah") "The process in which an inorganic ion is transported across a membrane.") -AnnotationAssertion( "inorganic ion membrane transport") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "transmembrane inorganic ion transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0098660") -AnnotationAssertion(rdfs:comment "Note that this term is not intended for use in annotating lateral movement within membranes.") -AnnotationAssertion(rdfs:label "inorganic ion transmembrane transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (inorganic anion transmembrane transport) - -AnnotationAssertion(Annotation( "GOC:mah") "The process in which an inorganic anion is transported across a membrane.") -AnnotationAssertion( "inorganic anion membrane transport") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "transmembrane inorganic anion transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0098661") -AnnotationAssertion(rdfs:comment "Note that this term is not intended for use in annotating lateral movement within membranes.") -AnnotationAssertion(rdfs:label "inorganic anion transmembrane transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (inorganic cation transmembrane transport) - -AnnotationAssertion(Annotation( "GOC:mah") "A process in which an inorganic cation is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.") -AnnotationAssertion( "GO:0015672") -AnnotationAssertion( "GO:0072511") -AnnotationAssertion( "inorganic cation membrane transport") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "transmembrane inorganic cation transport") -AnnotationAssertion( "divalent inorganic cation transport") -AnnotationAssertion( "monovalent inorganic cation transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0098662") -AnnotationAssertion(rdfs:comment "Note that this term is not intended for use in annotating lateral movement within membranes.") -AnnotationAssertion(rdfs:label "inorganic cation transmembrane transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (G protein-coupled serotonin receptor signaling pathway) - -AnnotationAssertion(Annotation( "GOC:mah") "The series of molecular signals generated as a consequence of a G protein-coupled serotonin receptor binding to one of its physiological ligands.") -AnnotationAssertion( "dos") -AnnotationAssertion( "2016-12-21T12:07:58Z") -AnnotationAssertion( "G-protein coupled serotonin receptor signaling pathway") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0098664") -AnnotationAssertion(rdfs:label "G protein-coupled serotonin receptor signaling pathway") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (serotonin receptor complex) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:bhm") Annotation( "GO_REF:0000088") Annotation( "PMID:16116092") "A protein complex that is capable of serotonin receptor activity.") -AnnotationAssertion( "dos") -AnnotationAssertion( "2016-12-21T12:24:56Z") -AnnotationAssertion( "5-HT receptor complex") -AnnotationAssertion( "5-hydroxytryptamine receptor complex") -AnnotationAssertion( "5HT receptor complex") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0098665") -AnnotationAssertion(rdfs:label "serotonin receptor complex") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (G protein-coupled serotonin receptor complex) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:bhm") Annotation( "GO_REF:0000088") "A protein complex that is capable of G protein-coupled serotonin receptor activity.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/12942"^^xsd:anyURI) -AnnotationAssertion( "dos") -AnnotationAssertion( "2016-12-21T12:28:12Z") -AnnotationAssertion( "G-protein coupled serotonin receptor complex") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0098666") -AnnotationAssertion(rdfs:label "G protein-coupled serotonin receptor complex") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (dopaminergic synapse) - -AnnotationAssertion(Annotation( "GOC:dos") "A synapse that uses dopamine as a neurotransmitter.") -AnnotationAssertion( "dos") -AnnotationAssertion( "2017-03-07T14:51:52Z") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0098691") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "dopaminergic synapse") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of synaptic vesicle cycle) - -AnnotationAssertion(Annotation( "GOC:dos") "Any process that modulates the frequency, rate or extent of the synaptic vesicle cycle.") -AnnotationAssertion( "dos") -AnnotationAssertion( "2017-03-21T16:06:48Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0098693") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "regulation of synaptic vesicle cycle") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (adenine import across plasma membrane) - -AnnotationAssertion(Annotation( "GOC:dos") "The directed movement of adenine from outside of a cell, across the plasma membrane and into the cytosol.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2012-12-06T14:51:42Z") -AnnotationAssertion( "GO:0061488") -AnnotationAssertion( "adenine import into cell") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0098702") -AnnotationAssertion(rdfs:label "adenine import across plasma membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (calcium ion import across plasma membrane) - -AnnotationAssertion(Annotation( "GOC:dos") "The directed movement of calcium ions from outside of a cell, across the plasma membrane and into the cytosol.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2013-02-07T13:07:59Z") -AnnotationAssertion( "GO:1990035") -AnnotationAssertion( "calcium ion import into cell") -AnnotationAssertion(Annotation( "GOC:vw") "calcium ion uptake into cell") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0098703") -AnnotationAssertion(rdfs:label "calcium ion import across plasma membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (carbohydrate import across plasma membrane) - -AnnotationAssertion(Annotation( "GOC:dos") "The directed movement of a carbohydrate from outside of a cell, across the plasma membrane and into the cytosol.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2012-05-31T02:45:02Z") -AnnotationAssertion( "GO:0097319") -AnnotationAssertion( "carbohydrate import into cell") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0098704") -AnnotationAssertion(rdfs:label "carbohydrate import across plasma membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (glucose import across plasma membrane) - -AnnotationAssertion(Annotation( "GOC:dos") "The directed movement of glucose from outside of a cell, across the plasma membrane and into the cytosol.") -AnnotationAssertion( "al") -AnnotationAssertion( "2012-12-06T14:54:07Z") -AnnotationAssertion( "GO:0061490") -AnnotationAssertion( "GO:1990821") -AnnotationAssertion( "glucose import into cell") -AnnotationAssertion( "high affinity glucose import") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0098708") -AnnotationAssertion(rdfs:label "glucose import across plasma membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (iron ion import across plasma membrane) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "PMID:8321236") "The directed movement of iron ions from outside of a cell, across the plasma membrane and into the cytosol.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2012-12-20T08:29:00Z") -AnnotationAssertion( "GO:0097459") -AnnotationAssertion( "GO:0097460") -AnnotationAssertion( "GO:0098707") -AnnotationAssertion( "iron ion import into cell") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:mah") "ferrous ion import into cell") -AnnotationAssertion( "ferrous iron import across plasma membrane") -AnnotationAssertion( "ferrous iron import into cell") -AnnotationAssertion(Annotation( "GOC:mah") "iron import into cell") -AnnotationAssertion( "GO:0098711") -AnnotationAssertion(rdfs:label "iron ion import across plasma membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (L-glutamate import across plasma membrane) - -AnnotationAssertion(Annotation( "GOC:dos") "The directed movement of L-glutamate from outside of a cell, across the plasma membrane and into the cytosol.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2013-06-12T12:32:47Z") -AnnotationAssertion( "GO:1903802") -AnnotationAssertion( "GO:1990123") -AnnotationAssertion( "L-glutamate(1-) import across plasma membrane") -AnnotationAssertion( "L-glutamate import into cell") -AnnotationAssertion( "L-glutamate(1-) import into cell") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0098712") -AnnotationAssertion(rdfs:label "L-glutamate import across plasma membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (sodium ion import across plasma membrane) - -AnnotationAssertion(Annotation( "GOC:dos") "The directed movement of sodium ions from outside of a cell, across the plasma membrane and into the cytosol.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2012-08-03T16:55:52Z") -AnnotationAssertion( "GO:0097369") -AnnotationAssertion( "GO:1990118") -AnnotationAssertion( "sodium import") -AnnotationAssertion( "sodium ion import into cell") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "sodium ion import") -AnnotationAssertion( "GO:0098719") -AnnotationAssertion(rdfs:label "sodium ion import across plasma membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (asymmetric stem cell division) - -AnnotationAssertion(Annotation( "GOC:dos") Annotation( "PMID:18513950") "Division of a stem cell during which it retains its identity and buds off a daughter cell with a new identity.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0098722") -AnnotationAssertion(rdfs:label "asymmetric stem cell division") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (skeletal muscle myofibril) - -AnnotationAssertion(Annotation( "GOC:dos") "A myofibril of a skeletal muscle fiber.") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0098723") -AnnotationAssertion(rdfs:label "skeletal muscle myofibril") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (maintenance of cell number) - -AnnotationAssertion(Annotation( "GOC:dos") "Any process by which the numbers of cells of a particular type or in a tissue are maintained.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0098727") -AnnotationAssertion(rdfs:label "maintenance of cell number") -SubClassOf( ) - -# Class: (germline stem cell asymmetric division) - -AnnotationAssertion(Annotation( "GOC:dos") "The self-renewing division of a germline stem cell, to produce a daughter stem cell and a daughter germ cell which will divide to form one or more gametes.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0098728") -AnnotationAssertion(rdfs:label "germline stem cell asymmetric division") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (import across plasma membrane) - -AnnotationAssertion(Annotation( "GOC:dos") "The directed movement of some substance from outside of a cell, across the plasma membrane and into the cytosol.") -AnnotationAssertion( "uptake") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0098739") -AnnotationAssertion(rdfs:label "import across plasma membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (cerebellar neuron development) - -AnnotationAssertion(Annotation( "GOC:dos") "The process whose specific outcome is the progression of a cerebellar neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0098749") -AnnotationAssertion(rdfs:label "cerebellar neuron development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (bone cell development) - -AnnotationAssertion(Annotation( "GOC:dos") "The process whose specific outcome is the progression of a bone cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0098751") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "Not to be used for manual annotation. Please choose a more specific cell development term or if not possible, bone or bone tissue development.") -AnnotationAssertion(rdfs:label "bone cell development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (detoxification) AnnotationAssertion(Annotation( "GOC:dos") "Any process that reduces or removes the toxicity of a toxic substance. These may include transport of the toxic substance away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance.") @@ -112405,26 +27767,6 @@ AnnotationAssertion(rdfs:label "deto SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (inorganic ion homeostasis) - -AnnotationAssertion(Annotation( "GOC:dos") "Any process involved in the maintenance of an internal steady state of inorganic ions within an organism or cell.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/24455"^^xsd:anyURI) -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0098771") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "inorganic ion homeostasis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (skin epidermis development) - -AnnotationAssertion(Annotation( "GOC:dos") "The process whose specific outcome is the progression of the skin epidermis over time, from its formation to the mature structure.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0098773") -AnnotationAssertion(rdfs:label "skin epidermis development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (presynapse) AnnotationAssertion(Annotation( "GOC:dos") "The part of a synapse that is part of the presynaptic cell.") @@ -112448,84 +27790,14 @@ SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (membrane protein complex) - -AnnotationAssertion(Annotation( "GOC:dos") "Any protein complex that is part of a membrane.") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0098796") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "membrane protein complex") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (plasma membrane protein complex) - -AnnotationAssertion(Annotation( "GOC:dos") "Any protein complex that is part of the plasma membrane.") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0098797") -AnnotationAssertion(rdfs:label "plasma membrane protein complex") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (regulation of renal system process) AnnotationAssertion(Annotation( "GOC:dos") "Any process that modulates the frequency, rate or extent of a system process, a multicellular organismal process carried out by the renal system.") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0098801") AnnotationAssertion(rdfs:label "regulation of renal system process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (plasma membrane signaling receptor complex) - -AnnotationAssertion(Annotation( "GOC:dos") "Any protein complex that is part of the plasma membrane and which functions as a signaling receptor.") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0098802") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.") -AnnotationAssertion(rdfs:label "plasma membrane signaling receptor complex") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (non-motile cilium membrane) - -AnnotationAssertion(Annotation( "GOC:cilia") Annotation( "GOC:dos") "The portion of the plasma membrane surrounding a non-motile cilium.") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "nonmotile primary cilium membrane") -AnnotationAssertion( "GO:0098804") -AnnotationAssertion(rdfs:label "non-motile cilium membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (nuclear chromosome segregation) - -AnnotationAssertion(Annotation( "GOC:dos") "The process in which genetic material, in the form of nuclear chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. Nuclear chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0098813") -AnnotationAssertion(rdfs:label "nuclear chromosome segregation") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (modulation of excitatory postsynaptic potential) - -AnnotationAssertion(Annotation( "GOC:dos") "Any process that modulates the frequency, rate or extent of excitatory postsynaptic potential (EPSP). EPSP is a process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0098815") -AnnotationAssertion(rdfs:label "modulation of excitatory postsynaptic potential") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (protein transport along microtubule) - -AnnotationAssertion(Annotation( "PMID:25987607") "The directed movement of a protein along a microtubule, mediated by motor proteins.") -AnnotationAssertion( "microtubule-based protein transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0098840") -AnnotationAssertion(rdfs:label "protein transport along microtubule") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - # Class: (podocyte foot) AnnotationAssertion(Annotation( "PMID:25324828") "A cell projection of a podocyte (glomerular visceral epithelial cell) forming a foot-like structure projecting from a podocyte primary projection, that wraps around capillaries of a renal glomerulus. Adjacent feet (pedicels) interdigitate, leaving thin filtration slits between them, which are covered by slit diaphragms.") @@ -112539,14 +27811,6 @@ AnnotationAssertion(rdfs:label "podo SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (lytic vacuole membrane) - -AnnotationAssertion(Annotation( "GOC:dos") "The lipid bilayer surrounding a lytic vacuole and separating its contents from the cytoplasm of the cell.") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0098852") -AnnotationAssertion(rdfs:label "lytic vacuole membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (actin-based cell projection) AnnotationAssertion(Annotation( "PMID:15661519") "A cell projection supported by an assembly of actin filaments, and which lacks microtubules.") @@ -112556,444 +27820,14 @@ AnnotationAssertion(rdfs:label "acti SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (intramembranous bone growth) - -AnnotationAssertion(Annotation( "PMID:26399686") "The increase in size or mass of an intramembranous bone that contributes to the shaping of the bone.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0098867") -AnnotationAssertion(rdfs:label "intramembranous bone growth") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (bone growth) - -AnnotationAssertion(Annotation( "GOC:dos") "The increase in size or mass of a bone that contributes to the shaping of that bone.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0098868") -AnnotationAssertion(rdfs:label "bone growth") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (postsynaptic actin cytoskeleton) - -AnnotationAssertion(Annotation( "GOC:dos") "The actin cytoskeleton that is part of a postsynapse.") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0098871") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "postsynaptic actin cytoskeleton") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (vesicle-mediated transport to the plasma membrane) - -AnnotationAssertion(Annotation( "GOC:dos") "The directed movement of substances to the plasma membrane in transport vesicles that fuse with the plasma membrane by exocytosis.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0098876") -AnnotationAssertion(rdfs:label "vesicle-mediated transport to the plasma membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (neurotransmitter receptor transport to plasma membrane) - -AnnotationAssertion(Annotation( "GOC:dos") "The directed movement of neurotransmitter receptor to the plasma membrane in transport vesicles.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0098877") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "neurotransmitter receptor transport to plasma membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (neurotransmitter receptor complex) - -AnnotationAssertion(Annotation( "GOC:dos") "Any protein complex that is capable of functioning as a neurotransmitter receptor.") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0098878") -AnnotationAssertion(rdfs:label "neurotransmitter receptor complex") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (synapse pruning) - -AnnotationAssertion(Annotation( "GOC:dos") Annotation( "PMID:12062020") Annotation( "PMID:18083105") Annotation( "PMID:22632716") Annotation( "PMID:29844190") "A cellular process that results in the controlled breakdown of synapse. After it starts the process is continuous until the synapse has disappeared.") -AnnotationAssertion(Annotation( "GOC:aruk") Annotation( "GOC:bc") Annotation( "PMID:22632716") "synapse clearance") -AnnotationAssertion(Annotation( "PMID:12062020") Annotation( ) "synapse disassembly") -AnnotationAssertion(Annotation( "GOC:aruk") Annotation( "GOC:bc") Annotation( "PMID:18083105") Annotation( "PMID:29844190") "synapse elimination") -AnnotationAssertion(Annotation( "GOC:aruk") Annotation( "GOC:bc") Annotation( "PMID:22632716") "synapse removal") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0098883") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "synapse pruning") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of action potential) - -AnnotationAssertion(Annotation( "GOC:dos") Annotation( "GOC:dph") Annotation( "GOC:go_curators") Annotation( "GOC:tb") Annotation( "ISBN:978-0-07-139011-8") "Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0098900") -AnnotationAssertion(rdfs:comment "The ion channels through which current flows during an action potential should be annotated to the process 'action potential'. Gene products involved in modulating the characteristics of an action potential via changing the expression levels or the activity of these channels (e.g. modulating their kinetics or voltage sensitivity) should be annotated to this regulation term.") -AnnotationAssertion(rdfs:label "regulation of action potential") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of cardiac muscle cell action potential) - -AnnotationAssertion(Annotation( "GOC:dos") Annotation( "GOC:mtg_cardiac_conduct_nov11") "Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a cardiac muscle cell. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0098901") -AnnotationAssertion(rdfs:label "regulation of cardiac muscle cell action potential") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of AV node cell action potential) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mtg_cardiac_conduct_nov11") "Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in an atrioventricular node myocyte. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2011-11-10T08:58:56Z") -AnnotationAssertion( "regulation of AV node cardiac muscle cell action potential") -AnnotationAssertion( "regulation of atrioventricular node cardiac muscle cell action potential") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0098904") -AnnotationAssertion(rdfs:label "regulation of AV node cell action potential") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (regulation of bundle of His cell action potential) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mtg_cardiac_conduct_nov11") "Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a cardiac muscle cell of the bundle of His. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2011-11-15T12:01:18Z") -AnnotationAssertion( "regulation of bundle of His cardiac muscle cell action potential") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0098905") -AnnotationAssertion(rdfs:label "regulation of bundle of His cell action potential") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of Purkinje myocyte action potential) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mtg_cardiac_conduct_nov11") "Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a Purkinje myocyte. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2011-11-10T08:58:56Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0098906") -AnnotationAssertion(rdfs:label "regulation of Purkinje myocyte action potential") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (regulation of SA node cell action potential) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mtg_cardiac_conduct_nov11") "Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in an SA node cardiac myocyte. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2011-11-10T08:50:15Z") -AnnotationAssertion( "regulation of SA node cardiac muscle cell action potential") -AnnotationAssertion( "regulation of SAN cardiac muscle cell action potential") -AnnotationAssertion( "regulation of sinoatrial node cardiac muscle cell action potential") -AnnotationAssertion( "regulation of sinus node cardiac muscle cell action potential") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0098907") -AnnotationAssertion(rdfs:label "regulation of SA node cell action potential") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (regulation of neuronal action potential) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:isa_complete") Annotation( "GOC:tb") "Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a neuron. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "generation of action potential") -AnnotationAssertion( "GO:0098908") -AnnotationAssertion(rdfs:label "regulation of neuronal action potential") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (anterograde trans-synaptic signaling) - -AnnotationAssertion(Annotation( "GOC:dos") "Cell-cell signaling from pre to post-synapse, across the synaptic cleft.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0098916") -AnnotationAssertion(rdfs:label "anterograde trans-synaptic signaling") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (retrograde trans-synaptic signaling) - -AnnotationAssertion(Annotation( "GOC:dos") "Cell-cell signaling from post to pre-synapse, across the synaptic cleft.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0098917") -AnnotationAssertion(rdfs:label "retrograde trans-synaptic signaling") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (retrograde trans-synaptic signaling by lipid) - -AnnotationAssertion(Annotation( "GOC:dos") "Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by a lipid ligand.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0098920") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "retrograde trans-synaptic signaling by lipid") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (postsynaptic signal transduction) - -AnnotationAssertion(Annotation( "GOC:dos") "Signal transduction in which the initial step occurs in a postsynapse.") -AnnotationAssertion(Annotation( ) "postsynaptic signaling pathway") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0098926") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "postsynaptic signal transduction") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (presynaptic signal transduction) - -AnnotationAssertion(Annotation( "GOC:dos") "Signal transduction in which the initial step occurs in a presynapse.") -AnnotationAssertion(Annotation( ) "presynaptic signaling pathway") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0098928") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "presynaptic signal transduction") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (axonal transport) - -AnnotationAssertion(Annotation( "ISBN:0815316194") "The directed movement of organelles or molecules along microtubules in axons.") -AnnotationAssertion( "Wikipedia:Axoplasmic_transport") -AnnotationAssertion( "axon cargo transport") -AnnotationAssertion( "axoplasmic transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0098930") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "axonal transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (retrograde dendritic transport) - -AnnotationAssertion(Annotation( "GOC:dos") "The directed movement of organelles or molecules along microtubules in a dendrite from the postsynapse towards the cell body.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0098934") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "retrograde dendritic transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (dendritic transport) - -AnnotationAssertion(Annotation( "ISBN:0815316194") "The directed movement of organelles or molecules along microtubules in dendrites.") -AnnotationAssertion( "dendrite cargo transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0098935") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "dendritic transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (anterograde dendritic transport) - -AnnotationAssertion(Annotation( "ISBN:0815316194") "The directed movement of organelles or molecules along microtubules from the cell body toward the postsynapse in dendrites.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0098937") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "anterograde dendritic transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (postsynaptic neurotransmitter receptor activity) - -AnnotationAssertion(Annotation( "GOC:dos") Annotation( "GOC:signaling") "Neurotransmitter receptor activity occuring in the postsynaptic membrane during synaptic transmission.") -AnnotationAssertion( "neurotransmitter receptor activity involved in chemical synaptic transmission") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0098960") -AnnotationAssertion(rdfs:label "postsynaptic neurotransmitter receptor activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (dendritic transport of ribonucleoprotein complex) - -AnnotationAssertion(Annotation( "GOC:dos") "The directed movement of a ribonucleoprotein complex along microtubules in nerve cell dendrites.") -AnnotationAssertion( "dendritic transport of RNP complex") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0098961") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "dendritic transport of ribonucleoprotein complex") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (regulation of postsynaptic neurotransmitter receptor activity) - -AnnotationAssertion(Annotation( "GOC:dos") "Any process that modulates the frequency, rate or extent of neurotransmitter receptor activity involved in synaptic transmission. Modulation may be via an effect on ligand affinity, or effector funtion such as ion selectivity or pore opening/closing in ionotropic receptors.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0098962") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "regulation of postsynaptic neurotransmitter receptor activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (exocytic insertion of neurotransmitter receptor to postsynaptic membrane) - -AnnotationAssertion(Annotation( "PMID:19503082") "The exocytic fusion of neurotransmitter receptor containing vesicles with the postsynaptic membrane resulting in the integration of NT receptors, enabling them to participate in neurotransmitter reception. This process includes tethering and docking steps that prepare vesicles for fusion.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0098967") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "exocytic insertion of neurotransmitter receptor to postsynaptic membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (neurotransmitter receptor transport to postsynaptic membrane) - -AnnotationAssertion(Annotation( "GOC:dos") "The directed movement of neurotransmitter receptor to the postsynaptic membrane in transport vesicles.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0098969") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "neurotransmitter receptor transport to postsynaptic membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (anterograde dendritic transport of neurotransmitter receptor complex) - -AnnotationAssertion(Annotation( "GOC:dos") "The directed movement of a neurotransmitter receptor complex along microtubules in nerve cell dendrites towards the postsynapse.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0098971") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "anterograde dendritic transport of neurotransmitter receptor complex") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (postsynaptic actin cytoskeleton organization) - -AnnotationAssertion(Annotation( "GOC:dos") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins in the postsynaptic actin cytoskeleton.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0098974") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "postsynaptic actin cytoskeleton organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (postsynapse of neuromuscular junction) - -AnnotationAssertion(Annotation( "GOC:dos") Annotation( "Wikipedia:Neuromuscular_junction&oldid=723623502") "The postsynapse of a neuromuscular junction. In vertebrate muscles this includes the motor end-plate, consisting of postjunctional folds of the sarcolemma.") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0098975") -AnnotationAssertion(rdfs:label "postsynapse of neuromuscular junction") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - # Class: (excitatory chemical synaptic transmission) AnnotationAssertion(Annotation( "GOC:dos") "Synaptic transmission that results in an excitatory postsynaptic potential.") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0098976") AnnotationAssertion(rdfs:label "excitatory chemical synaptic transmission") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (glutamatergic synapse) - -AnnotationAssertion(Annotation( "GOC:dos") "A synapse that uses glutamate as a neurotransmitter.") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0098978") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "glutamatergic synapse") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (cholinergic synapse) - -AnnotationAssertion(Annotation( "GOC:dos") "A synapse that uses acetylcholine as a neurotransmitter.") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0098981") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "cholinergic synapse") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (GABA-ergic synapse) - -AnnotationAssertion(Annotation( "GOC:dos") "A synapse that uses GABA as a neurotransmitter. These synapses are typically inhibitory.") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0098982") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "GABA-ergic synapse") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (G protein-coupled glutamate receptor activity) - -AnnotationAssertion(Annotation( "GOC:dos") "Combining with glutamate and transmitting a signal from one side of the membrane to the other by activating an associated G-protein, initiating a change in cell activity.") -AnnotationAssertion( "G-protein coupled glutamate receptor activity") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0098988") -AnnotationAssertion(rdfs:label "G protein-coupled glutamate receptor activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (neuronal dense core vesicle) - -AnnotationAssertion(Annotation( "GOC:dos") Annotation( "ISBN:978-0-07-181001-2") Annotation( "Wikipedia:Neuropeptide&oldid=713905176") "A dense core vesicle (granule) that is part of a neuron. These vesicles typically contain neuropeptides. They can be found in all parts of neurons, including the soma, dendrites, axonal swellings (varicosities) and synaptic terminals.") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0098992") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "neuronal dense core vesicle") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (vesicle-mediated transport in synapse) - -AnnotationAssertion(Annotation( "GOC:dos") "Any vesicle-mediated transport that occurs in a synapse.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0099003") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "vesicle-mediated transport in synapse") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - -# Class: (neuronal dense core vesicle membrane) - -AnnotationAssertion(Annotation( "GOC:dos") "The lipid bilayer surrounding a neuronal dense core vesicle.") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0099012") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "neuronal dense core vesicle membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (neuronal dense core vesicle organization) - -AnnotationAssertion(Annotation( "GOC:dos") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a neuronal dense core vesicle.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0099014") -AnnotationAssertion(rdfs:label "neuronal dense core vesicle organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (presynapse assembly) - -AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:bf") Annotation( "GOC:dos") Annotation( "PMID:24449494") "The aggregation, arrangement and bonding together of a set of components to form a presynapse.") -AnnotationAssertion(Annotation( "GOC:mah") "presynapse biogenesis") -AnnotationAssertion(Annotation( "PMID:24449494") "presynaptic terminal assembly") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0099054") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "presynapse assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (postsynapse assembly) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:dos") Annotation( "GOCL:PARL") "The aggregation, arrangement and bonding together of a set of components to form a postsynapse.") -AnnotationAssertion(Annotation( "GOC:mah") "postsynapse biogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0099068") -AnnotationAssertion(rdfs:label "postsynapse assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (regulation of postsynaptic membrane neurotransmitter receptor levels) - -AnnotationAssertion(Annotation( "GOC:dos") "Any process that regulates the the local concentration of neurotransmitter receptor at the postsynaptic membrane.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0099072") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "regulation of postsynaptic membrane neurotransmitter receptor levels") -SubClassOf( ) - # Class: (supramolecular complex) AnnotationAssertion(Annotation( "GOC:dos") "A cellular component that consists of an indeterminate number of proteins or macromolecular complexes, organized into a regular, higher-order structure such as a polymer, sheet, network or a fiber.") @@ -113008,322 +27842,14 @@ AnnotationAssertion(Annotation( "cellular_component") AnnotationAssertion( "GO:0099081") AnnotationAssertion(rdfs:label "supramolecular polymer") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (retrograde trans-synaptic signaling by neuropeptide) - -AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:bf") Annotation( "GOC:dos") Annotation( "PMID:19448629") "Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by a neuropeptide.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0099082") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "retrograde trans-synaptic signaling by neuropeptide") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (retrograde trans-synaptic signaling by neuropeptide, modulating synaptic transmission) - -AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:bf") Annotation( "GOC:dos") Annotation( "PMID:19448629") "Modulation of synaptic transmittion by cell-cell signaling across the synaptic cleft from postsynapse to presynapse, mediated by a neuropeptide.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0099083") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.") -AnnotationAssertion(rdfs:label "retrograde trans-synaptic signaling by neuropeptide, modulating synaptic transmission") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (microtubule polymerization based movement) - -AnnotationAssertion(Annotation( "GOC:cjm") Annotation( "ISBN:0815316194") "The movement of a cellular component as a result of microtubule polymerization.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0099098") -AnnotationAssertion(rdfs:label "microtubule polymerization based movement") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (microtubule-based transport) - -AnnotationAssertion(Annotation( "GOC:cjm") Annotation( "ISBN:0815316194") "A microtubule-based process that results in the transport of organelles, other microtubules, or other cellular components. Examples include motor-driven movement along microtubules and movement driven by polymerization or depolymerization of microtubules.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0099111") -AnnotationAssertion(rdfs:label "microtubule-based transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (microtubule polymerization based protein transport) - -AnnotationAssertion(Annotation( "GOC:dos") Annotation( "GOC:vw") Annotation( "PMID:11018050") "The transport of a protein driven by polymerization of a microtubule to which it is attached.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0099112") -AnnotationAssertion(rdfs:label "microtubule polymerization based protein transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (microtubule-based protein transport) - -AnnotationAssertion(Annotation( "GOC:vw") "A microtubule-based process that results in the transport of proteins.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0099118") -AnnotationAssertion(rdfs:label "microtubule-based protein transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (somato-dendritic dopamine secretion) - -AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:bf") Annotation( "PMID:21576241") "The regulated release of dopamine from the somatodendritic compartment (cell body or dendrites) of a neuron.") -AnnotationAssertion(Annotation( "PMID:21576241") "STD DA release") -AnnotationAssertion(Annotation( "PMID:21576241") "STD dopamine release") -AnnotationAssertion(Annotation( "PMID:21576241") "somatodendritic dopamine release") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0099123") -AnnotationAssertion(rdfs:label "somato-dendritic dopamine secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (axonal dopamine secretion) - -AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:bf") Annotation( "PMID:21576241") "The regulated release of dopamine from an axon.") -AnnotationAssertion(Annotation( "PMID:21576241") "axonal DA release") -AnnotationAssertion(Annotation( "PMID:21576241") "axonal dopamine release") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0099124") -AnnotationAssertion(rdfs:label "axonal dopamine secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (presynaptic actin cytoskeleton organization) - -AnnotationAssertion(Annotation( "GOC:dos") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins in the presynaptic actin cytoskeleton.") -AnnotationAssertion( "dos") -AnnotationAssertion( "2017-06-09T18:34:19Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0099140") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "presynaptic actin cytoskeleton organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (presynaptic actin cytoskeleton) - -AnnotationAssertion(Annotation( "GOC:dos") "The actin cytoskeleton that is part of a presynapse.") -AnnotationAssertion( "dos") -AnnotationAssertion( "2017-06-09T18:36:19Z") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0099143") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "presynaptic actin cytoskeleton") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of exocytic insertion of neurotransmitter receptor to postsynaptic membrane) - -AnnotationAssertion(Annotation( "GOC:dos") "Any process that modulates the frequency, rate or extent of exocytic fusion of neurotransmitter receptor containing vesicles into the postsynaptic membrane.") -AnnotationAssertion( "dos") -AnnotationAssertion( "2017-06-09T18:49:26Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0099145") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "regulation of exocytic insertion of neurotransmitter receptor to postsynaptic membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (cell-cell signaling via exosome) - -AnnotationAssertion(Annotation( "GOC:dos") Annotation( "PMID:19837038") "Cell-cell signaling in which the ligand is carried between cells by an exosome.") -AnnotationAssertion( "dos") -AnnotationAssertion( "2017-07-05T16:40:45Z") -AnnotationAssertion( "exosome mediated") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0099156") -AnnotationAssertion(rdfs:label "cell-cell signaling via exosome") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (trans-synaptic signaling via exosome) - -AnnotationAssertion(Annotation( "GOC:dos") Annotation( "PMID:19837038") "Transynaptic signaling in which the ligand is carried across the synapse by an exosome.") -AnnotationAssertion( "dos") -AnnotationAssertion( "2017-07-05T16:49:44Z") -AnnotationAssertion( "exosome mediated transynaptic signalling") -AnnotationAssertion( "trans-synaptic signalling via exosome") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0099157") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "trans-synaptic signaling via exosome") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (postsynaptic intermediate filament cytoskeleton) - -AnnotationAssertion(Annotation( "GOC:dos") Annotation( "PMID:25869803") "The intermediate filament cytoskeleton that is part of a postsynapse.") -AnnotationAssertion( "dos") -AnnotationAssertion( "2017-08-28T15:26:08Z") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0099160") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "postsynaptic intermediate filament cytoskeleton") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (postsynaptic modulation of chemical synaptic transmission) - -AnnotationAssertion(Annotation( "GOC:dos") "Any process, acting in the postsynapse that results in modulation of chemical synaptic transmission.") -AnnotationAssertion( "dos") -AnnotationAssertion( "2017-09-11T17:09:17Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0099170") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "postsynaptic modulation of chemical synaptic transmission") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (presynaptic modulation of chemical synaptic transmission) - -AnnotationAssertion(Annotation( "GOC:dos") "Any process, acting in the presynapse that results in modulation of chemical synaptic transmission.") -AnnotationAssertion( "dos") -AnnotationAssertion( "2017-09-11T17:09:31Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0099171") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "presynaptic modulation of chemical synaptic transmission") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (presynapse organization) - -AnnotationAssertion(Annotation( "GOC:dos") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a presynapse.") -AnnotationAssertion( "presynapse development") -AnnotationAssertion( "presynapse organisation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:BHF") "presynapse morphogenesis") -AnnotationAssertion(Annotation( "GOC:mah") "presynapse organization and biogenesis") -AnnotationAssertion( "GO:0099172") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "presynapse organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (postsynapse organization) - -AnnotationAssertion(Annotation( "GOC:dos") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a postsynapse.") -AnnotationAssertion( "postsynapse development") -AnnotationAssertion( "postsynapse organisation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:BHF") "postsynapse morphogenesis") -AnnotationAssertion(Annotation( "GOC:mah") "postsynapse organization and biogenesis") -AnnotationAssertion( "GO:0099173") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "postsynapse organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (regulation of presynapse organization) - -AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the physical form of a presynapse.") -AnnotationAssertion(Annotation( "GOC:mah") "regulation of presynapse organisation") -AnnotationAssertion( "regulation of presynapse structure") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:mah") "regulation of presynapse organization and biogenesis") -AnnotationAssertion( "GO:0099174") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "regulation of presynapse organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (regulation of postsynapse organization) - -AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the physical form of a postsynapse.") -AnnotationAssertion(Annotation( "GOC:mah") "regulation of postsynapse organisation") -AnnotationAssertion( "regulation of postsynapse structure") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:mah") "regulation of postsynapse organization and biogenesis") -AnnotationAssertion( "GO:0099175") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "regulation of postsynapse organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (regulation of trans-synaptic signaling) - -AnnotationAssertion(Annotation( "GOC:dos") "Any process that modulates the frequency, rate or extent of trans-synaptic signaling.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0099177") -AnnotationAssertion(rdfs:label "regulation of trans-synaptic signaling") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (presynaptic intermediate filament cytoskeleton) - -AnnotationAssertion(Annotation( "GOC:dos") "The intermediate filament cytoskeleton that is part of a presynapse.") -AnnotationAssertion( "dos") -AnnotationAssertion( "2017-12-01T18:10:21Z") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0099182") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "presynaptic intermediate filament cytoskeleton") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (postsynaptic intermediate filament cytoskeleton organization) - -AnnotationAssertion(Annotation( "GOC:dos") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprised of intermediate filament and their associated proteins in the postsynaptic cytoskeleton.") -AnnotationAssertion( "dos") -AnnotationAssertion( "2017-12-20T13:47:30Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0099185") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "postsynaptic intermediate filament cytoskeleton organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (presynaptic cytoskeleton organization) - -AnnotationAssertion(Annotation( "GOC:dos") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures and their associated proteins in the presynaptic cytoskeleton.") -AnnotationAssertion( "dos") -AnnotationAssertion( "2017-12-20T15:05:34Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0099187") -AnnotationAssertion(rdfs:label "presynaptic cytoskeleton organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (postsynaptic cytoskeleton organization) - -AnnotationAssertion(Annotation( "GOC:dos") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising cytoskeletal filaments and their associated proteins in the postsynaptic cytoskeleton.") -AnnotationAssertion( "dos") -AnnotationAssertion( "2017-12-20T15:06:57Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0099188") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "postsynaptic cytoskeleton organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (vesicle fusion to plasma membrane) AnnotationAssertion(Annotation( "GOC:aruk") Annotation( "GOC:bc") Annotation( "ISBN:0071120009") Annotation( "PMID:18618940") "Fusion of the membrane of a vesicle with the plasma membrane, thereby releasing its contents into the extracellular space.") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0099500") AnnotationAssertion(rdfs:label "vesicle fusion to plasma membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (exocytic vesicle membrane) - -AnnotationAssertion(Annotation( "GOC:dos") "The lipid bilayer surrounding an exocytic vesicle.") -AnnotationAssertion( "secretory vesicle membrane") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0099501") -AnnotationAssertion(rdfs:label "exocytic vesicle membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (secretory vesicle) - -AnnotationAssertion(Annotation( "GOC:dos") "A cytoplasmic, membrane bound vesicle that is capable of fusing to the plasma membrane to release its contents into the extracellular space.") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0099503") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "secretory vesicle") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (synaptic vesicle cycle) - -AnnotationAssertion(Annotation( "GOC:aruk") Annotation( "GOC:bc") Annotation( "PMID:15217342") "A biological process in which synaptic vesicles are loaded with neurotransmitters, move to the active zone, exocytose and are then recycled via endocytosis, ultimately leading to reloading with neurotransmitters.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0099504") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "synaptic vesicle cycle") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) # Class: (supramolecular fiber) @@ -113333,7 +27859,6 @@ AnnotationAssertion( "fibril") AnnotationAssertion( "GO:0099512") AnnotationAssertion(rdfs:label "supramolecular fiber") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf( ) # Class: (polymeric cytoskeletal fiber) @@ -113342,115 +27867,9 @@ AnnotationAssertion(Annotation( "cellular_component") AnnotationAssertion( "GO:0099513") AnnotationAssertion(rdfs:label "polymeric cytoskeletal fiber") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (actin filament-based transport) - -AnnotationAssertion(Annotation( "GOC:dos") Annotation( "GOC:dph") Annotation( "GOC:mah") Annotation( "GOC:tb") "The transport of organelles or other particles from one location in the cell to another along actin filaments.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2009-05-27T10:56:08Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0099515") -AnnotationAssertion(rdfs:label "actin filament-based transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (vesicle cytoskeletal trafficking) - -AnnotationAssertion(Annotation( "GOC:ecd") Annotation( "GOC:rl") "The directed movement of a vesicle along a cytoskeletal fiber such as a microtubule or and actin filament, mediated by motor proteins.") -AnnotationAssertion(Annotation( "GOC:rl") "cytoskeletal fiber-based vesicle localization") -AnnotationAssertion( "vesicle cytoskeletal transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0099518") -AnnotationAssertion(rdfs:label "vesicle cytoskeletal trafficking") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (dense core granule cytoskeletal transport) - -AnnotationAssertion(Annotation( "GOC:kmv") Annotation( "PMID:23358451") "The directed movement of dense core granules along cytoskeletal fibers, such as microtubules or actin filaments.") -AnnotationAssertion( "dense core vesicle cytoskeletal trafficking") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0099519") -AnnotationAssertion(rdfs:label "dense core granule cytoskeletal transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (cytosolic region) - -AnnotationAssertion(Annotation( "GOC:dos") "Any (proper) part of the cytosol of a single cell of sufficient size to still be considered cytosol.") -AnnotationAssertion( "region of cytosol") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0099522") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "cytosolic region") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (presynaptic cytosol) - -AnnotationAssertion(Annotation( "GOC:dos") "The region of the cytosol consisting of all cytosol that is part of the presynapse.") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0099523") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "presynaptic cytosol") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (postsynaptic cytosol) - -AnnotationAssertion(Annotation( "GOC:dos") "The region of the cytosol consisting of all cytosol that is part of the postsynapse.") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0099524") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "postsynaptic cytosol") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (G protein-coupled neurotransmitter receptor activity) - -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:fj") Annotation( "GOC:mah") "Combining with a neurotransmitter and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.") -AnnotationAssertion( "G-protein coupled neurotransmitter receptor activity") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0099528") -AnnotationAssertion(rdfs:label "G protein-coupled neurotransmitter receptor activity") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential) - -AnnotationAssertion(Annotation( "GOC:dos") "Neurotransmitter receptor activity occurring in the postsynaptic membrane that is involved in regulating postsynaptic membrane potential, either directly (ionotropic receptors) or indirectly (e.g. via GPCR activation of an ion channel).") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0099529") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (G protein-coupled receptor activity involved in regulation of postsynaptic membrane potential) - -AnnotationAssertion(Annotation( "GOC:dos") "A G protein-coupled receptor activity occurring in the postsynaptic membrane that is part of a GPCR signaling pathway that positively regulates ion channel activity in the postsynaptic membrane.") -AnnotationAssertion( "G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0099530") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "G protein-coupled receptor activity involved in regulation of postsynaptic membrane potential") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (presynaptic process involved in chemical synaptic transmission) - -AnnotationAssertion(Annotation( "GOC:dos") "The pathway leading to secretion of a neurotransmitter from the presynapse as part of synaptic transmission.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0099531") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "presynaptic process involved in chemical synaptic transmission") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - # Class: (synaptic signaling) AnnotationAssertion(Annotation( "GOC:dos") "Cell-cell signaling to, from or within a synapse.") @@ -113459,7 +27878,6 @@ AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "synaptic signaling") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectAllValuesFrom( )) @@ -113473,908 +27891,21 @@ AnnotationAssertion( "trans-synaptic signaling") SubClassOf( ) -# Class: (synaptic signaling via neuropeptide) - -AnnotationAssertion(Annotation( "GOC:dos") "Cell-cell signaling to or from a synapse, mediated by a peptide.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0099538") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "synaptic signaling via neuropeptide") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (trans-synaptic signaling by neuropeptide) - -AnnotationAssertion(Annotation( "GOC:dos") "Cell-cell signaling between presynapse and postsynapse mediated by a peptide ligand crossing the synaptic cleft.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0099540") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "trans-synaptic signaling by neuropeptide") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (trans-synaptic signaling by lipid) - -AnnotationAssertion(Annotation( "GOC:dos") "Cell-cell signaling from post to pre-synapse, across the synaptic cleft, mediated by a lipid.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0099541") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "trans-synaptic signaling by lipid") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (protein catabolic process, modulating synaptic transmission) - -AnnotationAssertion(Annotation( "GOC:dos") Annotation( "PMID:23083742") "Any protein degradation process, occurring at a presynapse, that regulates synaptic transmission.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0099546") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.") -AnnotationAssertion(rdfs:label "protein catabolic process, modulating synaptic transmission") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - -# Class: (regulation of translation at synapse, modulating synaptic transmission) - -AnnotationAssertion(Annotation( "GOC:dos") "Any process that modulates synaptic transmission by regulating translation occurring at the synapse.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0099547") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.") -AnnotationAssertion(rdfs:label "regulation of translation at synapse, modulating synaptic transmission") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - -# Class: (trans-synaptic signaling, modulating synaptic transmission) - -AnnotationAssertion(Annotation( "GOC:dos") "Cell-cell signaling between presynapse and postsynapse, across the synaptic cleft, that modulates the synaptic transmission properties of the synapse.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0099550") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.") -AnnotationAssertion(rdfs:label "trans-synaptic signaling, modulating synaptic transmission") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (trans-synaptic signaling by neuropeptide, modulating synaptic transmission) - -AnnotationAssertion(Annotation( "GOC:dos") "Cell-cell signaling between presynapse and postsynapse, via the vesicular release and reception of neuropeptide molecules, that modulates the synaptic transmission properties of the synapse.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0099551") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.") -AnnotationAssertion(rdfs:label "trans-synaptic signaling by neuropeptide, modulating synaptic transmission") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (trans-synaptic signaling by lipid, modulating synaptic transmission) - -AnnotationAssertion(Annotation( "GOC:dos") Annotation( "PMID:21531987") "Cell-cell signaling between presynapse and postsynapse, via the release and reception of lipid molecules, that modulates the synaptic transmission properties of the synapse.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0099552") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.") -AnnotationAssertion(rdfs:label "trans-synaptic signaling by lipid, modulating synaptic transmission") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (chemical synaptic transmission, postsynaptic) - -AnnotationAssertion(Annotation( "GOC:dos") "The part of synaptic transmission occurring in the post-synapse: a signal transduction pathway consisting of neurotransmitter receptor activation and its effects on postsynaptic membrane potential and the ionic composition of the postsynaptic cytosol.") -AnnotationAssertion(Annotation( ) "postsynaptic process involved in chemical synaptic transmission") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0099565") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "chemical synaptic transmission, postsynaptic") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (cytoplasmic region) - -AnnotationAssertion(Annotation( "GOC:dos") "Any (proper) part of the cytoplasm of a single cell of sufficient size to still be considered cytoplasm.") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0099568") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "cytoplasmic region") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (presynaptic cytoskeleton) - -AnnotationAssertion(Annotation( "GOC:dos") "The portion of the cytoskeleton contained within the presynapse.") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0099569") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "presynaptic cytoskeleton") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (postsynaptic cytoskeleton) - -AnnotationAssertion(Annotation( "GOC:dos") Annotation( "PMID:19889835") "The portion of the cytoskeleton contained within the postsynapse.") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0099571") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "postsynaptic cytoskeleton") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of protein catabolic process at synapse, modulating synaptic transmission) - -AnnotationAssertion(Annotation( "GOC:dos") "Any process that modulates synaptic transmission by regulating protein degradation at the synapse.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0099574") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.") -AnnotationAssertion(rdfs:label "regulation of protein catabolic process at synapse, modulating synaptic transmission") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - -# Class: (regulation of protein catabolic process at presynapse, modulating synaptic transmission) - -AnnotationAssertion(Annotation( "GOC:dos") "Any process that modulates synaptic transmission by regulating a catabolic process occurring at a presynapse.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0099575") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.") -AnnotationAssertion(rdfs:label "regulation of protein catabolic process at presynapse, modulating synaptic transmission") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of protein catabolic process at postsynapse, modulating synaptic transmission) - -AnnotationAssertion(Annotation( "GOC:dos") "Any process that modulates synaptic transmission by regulating a catabolic process occurring at a postsynapse.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0099576") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.") -AnnotationAssertion(rdfs:label "regulation of protein catabolic process at postsynapse, modulating synaptic transmission") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of translation at presynapse, modulating synaptic transmission) - -AnnotationAssertion(Annotation( "GOC:dos") "Any process that modulates synaptic transmission by regulating translation occurring at the presynapse.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0099577") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.") -AnnotationAssertion(rdfs:label "regulation of translation at presynapse, modulating synaptic transmission") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (regulation of translation at postsynapse, modulating synaptic transmission) - -AnnotationAssertion(Annotation( "GOC:dos") "Any process that modulates synaptic transmission by regulating translation occurring at the postsynapse.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0099578") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.") -AnnotationAssertion(rdfs:label "regulation of translation at postsynapse, modulating synaptic transmission") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential) - -AnnotationAssertion(Annotation( "GOC:dos") "A G protein-coupled neurotransmitter receptor activity, occurring in the postsynaptic membrane, involved in regulation of postsynaptic membrane potential.") -AnnotationAssertion( "G-protein coupled neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0099579") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (release of sequestered calcium ion into presynaptic cytosol) - -AnnotationAssertion(Annotation( "GOC:dos") "The process in which calcium ions sequestered in the endoplasmic reticulum, Golgi apparatus or mitochondria are released into the presynaptic cytosol.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0099585") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "release of sequestered calcium ion into presynaptic cytosol") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (release of sequestered calcium ion into postsynaptic cytosol) - -AnnotationAssertion(Annotation( "GOC:dos") "The process in which calcium ions sequestered in the endoplasmic reticulum, Golgi apparatus or mitochondria are released into the postsynaptic cytosol.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0099586") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "release of sequestered calcium ion into postsynaptic cytosol") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (inorganic ion import across plasma membrane) - -AnnotationAssertion(Annotation( "GOC:dos") "The directed movement of inorganic ions from outside of a cell, across the plasma membrane and into the cytosol.") -AnnotationAssertion( "inorganic ion import into cell") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0099587") -AnnotationAssertion(rdfs:label "inorganic ion import across plasma membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (serotonin receptor activity) - -AnnotationAssertion(Annotation( "GOC:dos") "Combining with the biogenic amine serotonin and transmitting a signal across a membrane by activating some effector activity. Serotonin (5-hydroxytryptamine) is a neurotransmitter and hormone found in vertebrates and invertebrates.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0099589") -AnnotationAssertion(rdfs:label "serotonin receptor activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of neurotransmitter receptor activity) - -AnnotationAssertion(Annotation( "GOC:dos") "Any process that modulates the frequency, rate or extent of neurotransmitter receptor activity. Modulation may be via an effect on ligand affinity, or effector funtion such as ion selectivity or pore opening/closing in ionotropic receptors.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0099601") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "regulation of neurotransmitter receptor activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (protein localization to axon) - -AnnotationAssertion(Annotation( "GOC:dos") Annotation( "PMID:26157139") "A process in which a protein is transported to or maintained in a location within an axon.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0099612") -AnnotationAssertion(rdfs:label "protein localization to axon") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (protein transport within plasma membrane) - -AnnotationAssertion(Annotation( "GOC:dos") "A process in which protein is transported from one region of the plasma membrane to another.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0099632") -AnnotationAssertion(rdfs:label "protein transport within plasma membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (neurotransmitter receptor transport) - -AnnotationAssertion(Annotation( "GOC:dos") "The directed movement of neurotransmitter receptors.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0099637") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "neurotransmitter receptor transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (axo-dendritic protein transport) - -AnnotationAssertion(Annotation( "ISBN:0815316194") "The directed movement of proteins along microtubules in neuron projections.") -AnnotationAssertion( "axonal protein transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0099640") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "axo-dendritic protein transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (anterograde axonal protein transport) - -AnnotationAssertion(Annotation( "GOC:dos") "The directed movement of proteins along microtubules from the cell body toward the cell periphery in nerve cell axons.") -AnnotationAssertion( "anterograde axon cargo transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0099641") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "anterograde axonal protein transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (retrograde axonal protein transport) - -AnnotationAssertion(Annotation( "ISBN:0815316194") "The directed movement of proteins along microtubules from the cell periphery toward the cell body in nerve cell axons.") -AnnotationAssertion( "retrograde axon cargo transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0099642") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "retrograde axonal protein transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (signal release from synapse) - -AnnotationAssertion(Annotation( "GOC:dos") "Any signal release from a synapse.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0099643") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "signal release from synapse") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - -# Class: (cell cortex region) - -AnnotationAssertion(Annotation( "GOC:dos") "The complete extent of cell cortex that underlies some some region of the plasma membrane.") -AnnotationAssertion( "perimembrane region") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0099738") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "cell cortex region") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of skeletal muscle contraction by action potential) - -AnnotationAssertion(Annotation( "GOC:cjm") Annotation( "GOC:obol") "Any action potential process that regulates skeletal muscle contraction.") -AnnotationAssertion( "cjm") -AnnotationAssertion( "2015-04-02T04:13:19Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0100001") -AnnotationAssertion(rdfs:label "regulation of skeletal muscle contraction by action potential") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (vascular endothelial cell proliferation) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_telomere") Annotation( "GOC:nc") Annotation( "PMID:23201774") "The multiplication or reproduction of blood vessel endothelial cells, resulting in the expansion of a cell population.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0101023") -AnnotationAssertion(rdfs:label "vascular endothelial cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (mitotic nuclear membrane organization) - -AnnotationAssertion(Annotation( "GOC:vw") Annotation( "PMID:15147872") "A mitotic cell cycle process which results in the assembly, arrangement, or disassembly of the nuclear inner or outer membrane during mitosis.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/19949"^^xsd:anyURI) -AnnotationAssertion( "nuclear membrane organization involved in mitotic nuclear division") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0101024") -AnnotationAssertion(rdfs:comment "This process only occurs in organisms which undergo 'closed mitosis' without nuclear breakdown.") -AnnotationAssertion(rdfs:label "mitotic nuclear membrane organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - -# Class: (nuclear membrane biogenesis) - -AnnotationAssertion(Annotation( "GOC:vw") "The process in which a nuclear membrane is synthesized, aggregates, and bonds together.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0101025") -AnnotationAssertion(rdfs:label "nuclear membrane biogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cellular response to environmental stimulus) - -AnnotationAssertion(Annotation( "GOC:dos") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an environmental stimulus.") -AnnotationAssertion( "dos") -AnnotationAssertion( "2017-02-17T16:02:42Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0104004") -AnnotationAssertion(rdfs:label "cellular response to environmental stimulus") -SubClassOf( ) - -# Class: (regulation of inflammatory response to wounding) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_miRNA") Annotation( "GOC:rph") Annotation( "PMID:26022821") "Any process that modulates the frequency, rate or extent of the inflammatory response to wounding.") -AnnotationAssertion( "hjd") -AnnotationAssertion( "2017-04-28T20:03:14Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0106014") -AnnotationAssertion(rdfs:label "regulation of inflammatory response to wounding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of inflammatory response to wounding) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_miRNA") Annotation( "GOC:rph") Annotation( "PMID:26022821") "Any process that stops, prevents, or reduces the frequency, rate or extent of the inflammatory response to wounding.") -AnnotationAssertion( "hjd") -AnnotationAssertion( "2017-04-28T20:09:46Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0106015") -AnnotationAssertion(rdfs:label "negative regulation of inflammatory response to wounding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (positive regulation of inflammatory response to wounding) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_miRNA") Annotation( "GOC:rph") Annotation( "PMID:26022821") "Any process that activates or increases the frequency, rate or extent of the inflammatory response to wounding.") -AnnotationAssertion( "hjd") -AnnotationAssertion( "2017-04-28T20:16:31Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0106016") -AnnotationAssertion(rdfs:label "positive regulation of inflammatory response to wounding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (neuron projection organization) - -AnnotationAssertion(Annotation( "GOC:aruk") Annotation( "GOC:bc") Annotation( "PMID:11585923") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a neuron, e.g. an axon, or a dendrite.") -AnnotationAssertion( "hjd") -AnnotationAssertion( "2017-06-23T18:30:18Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0106027") -AnnotationAssertion(rdfs:label "neuron projection organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of vesicle fusion with Golgi apparatus) - -AnnotationAssertion(Annotation( "GOC:se") Annotation( "PMID:26195667") "Any process that modulates the frequency, rate or extent of vesicle fusion with Golgi apparatus.") -AnnotationAssertion( "hjd") -AnnotationAssertion( "2019-06-27T15:12:22Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0106214") -AnnotationAssertion(rdfs:label "regulation of vesicle fusion with Golgi apparatus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of vesicle fusion with Golgi apparatus) - -AnnotationAssertion(Annotation( "GOC:se") Annotation( "PMID:26195667") "Any process that stops, prevents or reduces the frequency, rate or extent of vesicle fustion with Golgi apparatus.") -AnnotationAssertion( "hjd") -AnnotationAssertion( "2019-06-27T15:17:17Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0106215") -AnnotationAssertion(rdfs:label "negative regulation of vesicle fusion with Golgi apparatus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of vesicle fusion with Golgi apparatus) - -AnnotationAssertion(Annotation( "GOC:se") Annotation( "PMID:26195667") "Any process that activates or increases the frequency, rate or extent of vesicle fusion with Golgi apparatus.") -AnnotationAssertion( "hjd") -AnnotationAssertion( "2019-06-27T15:20:59Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0106216") -AnnotationAssertion(rdfs:label "positive regulation of vesicle fusion with Golgi apparatus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of basement membrane organization) - -AnnotationAssertion(Annotation( "GOC:ha") Annotation( "PMID:27404358") "Any process that modulates the frequency, rate or extent of the assembly, disassembly or arrangement of constituent parts of the basement membrane.") -AnnotationAssertion( "kmv") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0110011") -AnnotationAssertion(rdfs:label "regulation of basement membrane organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of actomyosin structure organization) - -AnnotationAssertion(Annotation( "GOC:lf") Annotation( "PMID:22790195") "Any process that modulates the frequency, rate or extent of the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures containing both actin and myosin or paramyosin.") -AnnotationAssertion( "kmv") -AnnotationAssertion( "2017-06-20T19:28:58Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0110020") -AnnotationAssertion(rdfs:label "regulation of actomyosin structure organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cardiac muscle myoblast proliferation) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_miRNA") Annotation( "GOC:rph") Annotation( "PMID:26512644") "The multiplication or reproduction of cardiac muscle myoblasts, resulting in the expansion of a cardiac muscle myoblast cell population. A cardiac myoblast is a precursor cell that has been committed to a cardiac muscle cell fate but retains the ability to divide and proliferate throughout life.") -AnnotationAssertion( "kmv") -AnnotationAssertion( "2017-06-29T14:35:24Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0110021") -AnnotationAssertion(rdfs:label "cardiac muscle myoblast proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of cardiac muscle myoblast proliferation) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_miRNA") Annotation( "GOC:rph") Annotation( "PMID:26512644") "Any process that modulates the frequency, rate or extent of cardiac muscle myoblast proliferation.") -AnnotationAssertion( "kmv") -AnnotationAssertion( "2017-06-29T15:11:47Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0110022") -AnnotationAssertion(rdfs:label "regulation of cardiac muscle myoblast proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of cardiac muscle myoblast proliferation) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_miRNA") Annotation( "GOC:rph") Annotation( "PMID:26512644") "Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle myoblast proliferation.") -AnnotationAssertion( "kmv") -AnnotationAssertion( "2017-06-29T15:18:30Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0110023") -AnnotationAssertion(rdfs:label "negative regulation of cardiac muscle myoblast proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of cardiac muscle myoblast proliferation) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_miRNA") Annotation( "GOC:rph") Annotation( "PMID:26512644") "Any process that activates or increases the frequency, rate or extent of cardiac muscle myoblast proliferation.") -AnnotationAssertion( "kmv") -AnnotationAssertion( "2017-06-29T15:24:16Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0110024") -AnnotationAssertion(rdfs:label "positive regulation of cardiac muscle myoblast proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (pharynx morphogenesis) - -AnnotationAssertion(Annotation( "GOC:rz") Annotation( "PMID:20805556") "The process in which the anatomical structures of the pharynx are generated and organized.") -AnnotationAssertion( "kmv") -AnnotationAssertion( "2017-07-24T20:51:28Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0110040") -AnnotationAssertion(rdfs:label "pharynx morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of pharynx morphogenesis) - -AnnotationAssertion(Annotation( "GOC:rz") Annotation( "PMID:20805556") "Any process that modulates the frequency, rate or extent of pharynx morphogenesis, the process in which the anatomical structure of the pharynx is generated and organized.") -AnnotationAssertion( "kmv") -AnnotationAssertion( "2017-07-24T21:00:20Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0110041") -AnnotationAssertion(rdfs:label "regulation of pharynx morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of pharynx morphogenesis) - -AnnotationAssertion(Annotation( "GOC:rz") Annotation( "PMID:20805556") "Any process that stops, prevents, or reduces the frequency, rate or extent of pharynx morphogenesis.") -AnnotationAssertion( "kmv") -AnnotationAssertion( "2017-07-24T21:05:08Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0110042") -AnnotationAssertion(rdfs:label "negative regulation of pharynx morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of pharynx morphogenesis) - -AnnotationAssertion(Annotation( "GOC:rz") Annotation( "PMID:20805556") "Any process that activates or increases the frequency, rate or extent of pharynx morphogenesis.") -AnnotationAssertion( "kmv") -AnnotationAssertion( "2017-07-24T21:09:48Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0110043") -AnnotationAssertion(rdfs:label "positive regulation of pharynx morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of actin filament organization) - -AnnotationAssertion(Annotation( "GOC:kmv") "Any process that modulates the frequency, rate or extent of actin filament organization.") -AnnotationAssertion( "kmv") -AnnotationAssertion( "2017-09-20T19:52:57Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0110053") -AnnotationAssertion(rdfs:label "regulation of actin filament organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (regulation of blood vessel endothelial cell differentiation) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_miRNA") Annotation( "GOC:rph") Annotation( "PMID:23072816") "Any process that modulates the frequency, rate or extent of blood vessel endothelial cell differentiation.") -AnnotationAssertion( "kmv") -AnnotationAssertion( "2017-10-23T14:32:09Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0110057") -AnnotationAssertion(rdfs:label "regulation of blood vessel endothelial cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (positive regulation of blood vessel endothelial cell differentiation) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_miRNA") Annotation( "GOC:rph") Annotation( "PMID:23072816") "Any process that activates or increases the frequency, rate or extent of blood vessel endothelial cell differentiation.") -AnnotationAssertion( "kmv") -AnnotationAssertion( "2017-10-23T14:38:19Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0110058") -AnnotationAssertion(rdfs:label "positive regulation of blood vessel endothelial cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (negative regulation of blood vessel endothelial cell differentiation) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_miRNA") Annotation( "GOC:rph") Annotation( "PMID:23072816") "Any process that stops, prevents, or reduces the frequency, rate or extent of blood vessel endothelial cell differentiation.") -AnnotationAssertion( "kmv") -AnnotationAssertion( "2017-10-23T14:47:29Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0110059") -AnnotationAssertion(rdfs:label "negative regulation of blood vessel endothelial cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (vesicle-mediated intercellular transport) - -AnnotationAssertion(Annotation( "GOC:sp") Annotation( "PMID:29328915") Annotation( "PMID:29328916") "A cellular transport process in which transported substances are moved in extracellular vesicles between cells; transported substances are enclosed in the vesicle lumen or located in the extracellular vesicle membrane.") -AnnotationAssertion( "kmv") -AnnotationAssertion( "2018-01-29T14:46:52Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0110077") -AnnotationAssertion(rdfs:label "vesicle-mediated intercellular transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of placenta blood vessel development) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_miRNA") Annotation( "GOC:rph") Annotation( "PMID:27748453") "Any process that modulates the frequency, rate or extent of placenta blood vessel development.") -AnnotationAssertion( "kmv") -AnnotationAssertion( "2018-02-01T14:49:12Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0110079") -AnnotationAssertion(rdfs:label "regulation of placenta blood vessel development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of placenta blood vessel development) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_miRNA") Annotation( "GOC:rph") Annotation( "PMID:27748453") "Any process that activates or increases the frequency, rate or extent of placenta blood vessel development.") -AnnotationAssertion( "kmv") -AnnotationAssertion( "2018-02-01T14:55:30Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0110080") -AnnotationAssertion(rdfs:label "positive regulation of placenta blood vessel development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of placenta blood vessel development) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_miRNA") Annotation( "GOC:rph") Annotation( "PMID:27748453") "Any process that stops, prevents or reduces the frequency, rate or extent of placenta blood vessel development.") -AnnotationAssertion( "kmv") -AnnotationAssertion( "2018-02-01T15:01:11Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0110081") -AnnotationAssertion(rdfs:label "negative regulation of placenta blood vessel development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (hippocampal neuron apoptotic process) - -AnnotationAssertion(Annotation( "GOC:sl") Annotation( "PMID:18940801") "Any apoptotic process that occurs in a hippocampal neuron.") -AnnotationAssertion( "kmv") -AnnotationAssertion( "2018-02-13T21:06:23Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0110088") -AnnotationAssertion(rdfs:label "hippocampal neuron apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of hippocampal neuron apoptotic process) - -AnnotationAssertion(Annotation( "GOC:sl") Annotation( "PMID:18940801") "Any process that modulates the occurrence or rate of cell death by apoptotic process in hippocampal neurons.") -AnnotationAssertion( "kmv") -AnnotationAssertion( "2018-02-13T21:18:29Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0110089") -AnnotationAssertion(rdfs:label "regulation of hippocampal neuron apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of hippocampal neuron apoptotic process) - -AnnotationAssertion(Annotation( "GOC:sl") Annotation( "PMID:18940801") "Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process in hippocampal neurons.") -AnnotationAssertion( "kmv") -AnnotationAssertion( "2018-02-13T21:22:18Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0110090") -AnnotationAssertion(rdfs:label "positive regulation of hippocampal neuron apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of hippocampal neuron apoptotic process) - -AnnotationAssertion(Annotation( "GOC:sl") Annotation( "PMID:18940801") "Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process in hippocampal neurons.") -AnnotationAssertion( "kmv") -AnnotationAssertion( "2018-02-13T21:25:01Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0110091") -AnnotationAssertion(rdfs:label "negative regulation of hippocampal neuron apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cellular detoxification of aldehyde) - -AnnotationAssertion(Annotation( "GOC:vw") Annotation( "PMID:25656103") "Any process carried out at the cellular level that reduces or removes the toxicity of an aldehyde. These may include transport of aldehydes away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance.") -AnnotationAssertion( "kmv") -AnnotationAssertion( "2018-02-16T21:19:20Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0110095") -AnnotationAssertion(rdfs:label "cellular detoxification of aldehyde") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cellular response to aldehyde) - -AnnotationAssertion(Annotation( "GOC:vw") Annotation( "PMID:25656103") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aldehyde stimulus.") -AnnotationAssertion( "kmv") -AnnotationAssertion( "2018-02-16T21:29:18Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0110096") -AnnotationAssertion(rdfs:label "cellular response to aldehyde") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of animal organ morphogenesis) - -AnnotationAssertion(Annotation( "GOC:kmv") "Any process that activates or increases the frequency, rate or extent of animal organ morphogenesis.") -AnnotationAssertion( "kmv") -AnnotationAssertion( "2018-07-05T14:10:14Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0110110") -AnnotationAssertion(rdfs:label "positive regulation of animal organ morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (negative regulation of animal organ morphogenesis) - -AnnotationAssertion(Annotation( "GOC:kmv") "Any process that stops, prevents, or reduces the frequency, rate or extent of animal organ morphogenesis.") -AnnotationAssertion( "kmv") -AnnotationAssertion( "2018-07-05T14:25:21Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0110111") -AnnotationAssertion(rdfs:label "negative regulation of animal organ morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (regulation of lipid transporter activity) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_miRNA") Annotation( "GOC:rph") Annotation( "PMID:27365390") "Any process that modulates the frequency, rate, or extent of lipid transporter activity.") -AnnotationAssertion( "kmv") -AnnotationAssertion( "2018-07-06T18:53:55Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0110112") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "regulation of lipid transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of lipid transporter activity) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_miRNA") Annotation( "GOC:rph") Annotation( "PMID:27365390") "Any process that increases the frequency, rate, or extent of lipid transporter activity.") -AnnotationAssertion( "kmv") -AnnotationAssertion( "2018-07-06T19:14:13Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0110113") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "positive regulation of lipid transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (negative regulation of lipid transporter activity) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_miRNA") Annotation( "GOC:rph") Annotation( "PMID:27365390") "Any process that decreases the frequency, rate, or extent of lipid transporter activity.") -AnnotationAssertion( "kmv") -AnnotationAssertion( "2018-07-06T19:21:44Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0110114") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "negative regulation of lipid transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (regulation of compound eye photoreceptor cell differentiation) - -AnnotationAssertion(Annotation( "GOC:ha") Annotation( "PMID:16377567") "Any process that modulates the frequency, rate or extent of compound eye photoreceptor cell differentiation.") -AnnotationAssertion( "kmv") -AnnotationAssertion( "2018-07-16T18:08:49Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0110116") -AnnotationAssertion(rdfs:label "regulation of compound eye photoreceptor cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of compound eye photoreceptor cell differentiation) - -AnnotationAssertion(Annotation( "GOC:ha") Annotation( "PMID:16377567") "Any process that activates or increases the frequency, rate or extent of compound eye photoreceptor cell differentiation.") -AnnotationAssertion( "kmv") -AnnotationAssertion( "2018-07-16T18:13:28Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0110117") -AnnotationAssertion(rdfs:label "positive regulation of compound eye photoreceptor cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of compound eye photoreceptor cell differentiation) - -AnnotationAssertion(Annotation( "GOC:ha") Annotation( "PMID:16377567") "Any process that stops, prevents, or reduces the frequency, rate or extent of compound eye photoreceptor cell differentiation.") -AnnotationAssertion( "kmv") -AnnotationAssertion( "2018-07-16T18:15:52Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0110118") -AnnotationAssertion(rdfs:label "negative regulation of compound eye photoreceptor cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (myotube cell migration) - -AnnotationAssertion(Annotation( "GOC:ha") Annotation( "PMID:29122742") "The orderly movement of a myotube cell from one site to another, often during the development of a multicellular organism. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate, and fuse.") -AnnotationAssertion( "kmv") -AnnotationAssertion( "2018-08-22T20:58:09Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0110122") -AnnotationAssertion(rdfs:label "myotube cell migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of myotube cell migration) - -AnnotationAssertion(Annotation( "GOC:ha") Annotation( "PMID:29122742") "Any process that modulates the frequency, rate or extent of myotube cell migration.") -AnnotationAssertion( "kmv") -AnnotationAssertion( "2018-08-22T21:06:53Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0110123") -AnnotationAssertion(rdfs:label "regulation of myotube cell migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of myotube cell migration) - -AnnotationAssertion(Annotation( "GOC:ha") Annotation( "PMID:29122742") "Any process that activates, maintains or increases the frequency, rate or extent of myotube cell migration.") -AnnotationAssertion( "kmv") -AnnotationAssertion( "2018-08-22T21:09:38Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0110124") -AnnotationAssertion(rdfs:label "positive regulation of myotube cell migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of myotube cell migration) - -AnnotationAssertion(Annotation( "GOC:ha") Annotation( "PMID:29122742") "Any process that stops, prevents, or reduces the frequency, rate or extent of myotube cell migration.") -AnnotationAssertion( "kmv") -AnnotationAssertion( "2018-08-22T21:12:47Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0110125") -AnnotationAssertion(rdfs:label "negative regulation of myotube cell migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of imaginal disc-derived leg joint morphogenesis) - -AnnotationAssertion(Annotation( "GOC:ha") Annotation( "PMID:25329825") "Any process that modulates the frequency, rate or extent of imaginal disc-derived leg joint morphogenesis, the process in which the anatomical structure of the imaginal disc-derived leg joint is generated and organized.") -AnnotationAssertion( "kmv") -AnnotationAssertion( "2019-02-12T15:31:25Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0110137") -AnnotationAssertion(rdfs:label "regulation of imaginal disc-derived leg joint morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of imaginal disc-derived leg joint morphogenesis) - -AnnotationAssertion(Annotation( "GOC:ha") Annotation( "PMID:25329825") "Any process that activates or increases the frequency, rate or extent of imaginal disc-derived leg joint morphogenesis.") -AnnotationAssertion( "kmv") -AnnotationAssertion( "2019-02-12T15:37:05Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0110138") -AnnotationAssertion(rdfs:label "positive regulation of imaginal disc-derived leg joint morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of imaginal disc-derived leg joint morphogenesis) - -AnnotationAssertion(Annotation( "GOC:ha") Annotation( "PMID:25329825") "Any process that stops, prevents, or reduces the frequency, rate or extent of imaginal disc-derived leg joint morphogenesis.") -AnnotationAssertion( "kmv") -AnnotationAssertion( "2019-02-12T15:40:09Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0110139") -AnnotationAssertion(rdfs:label "negative regulation of imaginal disc-derived leg joint morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (cellular anatomical entity) AnnotationAssertion(Annotation( "GOC:kmv") "A part of a cellular organism that is either an immaterial entity or a material entity with granularity above the level of a protein complex but below that of an anatomical system. Or, a substance produced by a cellular organism with granularity above the level of a protein complex.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/24200"^^xsd:anyURI) AnnotationAssertion( "kmv") AnnotationAssertion( "2019-08-12T18:01:37Z") AnnotationAssertion( "cellular_component") AnnotationAssertion( "GO:0110165") +AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "cellular anatomical entity") SubClassOf( ) SubClassOf( ) SubClassOf( ) -# Class: (regulation of glutamatergic neuron differentiation) - -AnnotationAssertion(Annotation( "PMID:24030726") "Any process that modulates the frequency, rate or extent of glutamatergic neuron differentiation.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/13107"^^xsd:anyURI) -AnnotationAssertion( "krc") -AnnotationAssertion( "2017-03-01T16:10:27Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0120006") -AnnotationAssertion(rdfs:label "regulation of glutamatergic neuron differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of glutamatergic neuron differentiation) - -AnnotationAssertion(Annotation( "PMID:24030726") "Any process that stops, prevents or reduces the frequency, rate or extent of glutamatergic neuron differentiation.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/13107"^^xsd:anyURI) -AnnotationAssertion( "krc") -AnnotationAssertion( "2017-03-01T16:25:50Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0120007") -AnnotationAssertion(rdfs:label "negative regulation of glutamatergic neuron differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of glutamatergic neuron differentiation) - -AnnotationAssertion(Annotation( "PMID:24030726") "Any process that activates or increases the frequency, rate or extent of glutamatergic neuron differentiation.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/13107"^^xsd:anyURI) -AnnotationAssertion( "krc") -AnnotationAssertion( "2017-03-01T16:35:45Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0120008") -AnnotationAssertion(rdfs:label "positive regulation of glutamatergic neuron differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (somatostatin binding) - -AnnotationAssertion(Annotation( "GOC:cvs") Annotation( "PMID:20472043") "Binding to somatostatin, a polypeptide hormone involved in regulating pancreatic alpha and pancreatic beta cells and controlling growth hormone secretion as well as many other functions. Somatostatin is produced by several cell types including pancreatic delta cells. There are several different mature forms of somatostatin.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/13143"^^xsd:anyURI) -AnnotationAssertion( "krc") -AnnotationAssertion( "2017-03-17T14:54:21Z") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0120023") -AnnotationAssertion(rdfs:label "somatostatin binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (plasma membrane bounded cell projection) AnnotationAssertion(Annotation( "GOC:krc") "A prolongation or process extending from a cell and that is bounded by plasma membrane, e.g. a cilium, lamellipodium, or axon.") @@ -114384,484 +27915,6 @@ AnnotationAssertion( AnnotationAssertion( "cellular_component") AnnotationAssertion( "GO:0120025") AnnotationAssertion(rdfs:label "plasma membrane bounded cell projection") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (plasma membrane bounded cell projection assembly) - -AnnotationAssertion(Annotation( "GOC:krc") "Formation of a prolongation or process extending and that is bounded by plasma membrane, e.g. a cilium, lamellipodium, or axon.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/13298"^^xsd:anyURI) -AnnotationAssertion( "krc") -AnnotationAssertion( "2017-04-24T23:56:08Z") -AnnotationAssertion(Annotation( "GOC:krc") Annotation( "GOC:rjd") Annotation( "PMID:10328951") Annotation( "PMID:9096956") "eupodium") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0120031") -AnnotationAssertion(rdfs:label "plasma membrane bounded cell projection assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of plasma membrane bounded cell projection assembly) - -AnnotationAssertion(Annotation( "GOC:krc") "Any process that modulates the rate, frequency, or extent of plasma membrane bounded cell projection assembly.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/13298"^^xsd:anyURI) -AnnotationAssertion( "krc") -AnnotationAssertion( "2017-04-26T04:27:04Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0120032") -AnnotationAssertion(rdfs:label "regulation of plasma membrane bounded cell projection assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of plasma membrane bounded cell projection assembly) - -AnnotationAssertion(Annotation( "GOC:krc") "Any process that stops, prevents or reduces the frequency, rate or extent of plasma membrane bounded cell projection assembly.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/13298"^^xsd:anyURI) -AnnotationAssertion( "krc") -AnnotationAssertion( "2017-04-26T04:34:31Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0120033") -AnnotationAssertion(rdfs:label "negative regulation of plasma membrane bounded cell projection assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of plasma membrane bounded cell projection assembly) - -AnnotationAssertion(Annotation( "GOC:krc") "Any process that activates or increases the frequency, rate or extent of plasma membrane bounded cell projection assembly.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/13298"^^xsd:anyURI) -AnnotationAssertion( "krc") -AnnotationAssertion( "2017-04-26T04:34:45Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0120034") -AnnotationAssertion(rdfs:label "positive regulation of plasma membrane bounded cell projection assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (regulation of plasma membrane bounded cell projection organization) - -AnnotationAssertion(Annotation( "GOC:krc") "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of plasma membrane bounded cell projections.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/13298"^^xsd:anyURI) -AnnotationAssertion( "krc") -AnnotationAssertion( "2017-04-26T16:02:06Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0120035") -AnnotationAssertion(rdfs:label "regulation of plasma membrane bounded cell projection organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (plasma membrane bounded cell projection organization) - -AnnotationAssertion(Annotation( "GOC:krc") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a plasma membrane bounded prolongation or process extending from a cell, e.g. a cilium or axon.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/13298"^^xsd:anyURI) -AnnotationAssertion( "krc") -AnnotationAssertion( "2017-04-26T16:07:02Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0120036") -AnnotationAssertion(rdfs:label "plasma membrane bounded cell projection organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (plasma membrane bounded cell projection morphogenesis) - -AnnotationAssertion(Annotation( "GOC:krc") "The process in which the anatomical structures of a plasma membrane bounded cell projection are generated and organized.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/13298"^^xsd:anyURI) -AnnotationAssertion( "krc") -AnnotationAssertion( "2017-04-28T23:39:37Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0120039") -AnnotationAssertion(rdfs:label "plasma membrane bounded cell projection morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (neuron projection cytoplasm) - -AnnotationAssertion(Annotation( "GOC:ha") "All of the contents of a plasma membrane bounded neuron projection, excluding the plasma membrane surrounding the projection.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/14472"^^xsd:anyURI) -AnnotationAssertion( "krc") -AnnotationAssertion( "2017-11-01T18:58:12Z") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0120111") -AnnotationAssertion(rdfs:label "neuron projection cytoplasm") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (glucagon processing) - -AnnotationAssertion(Annotation( "PMID:28719828") "The formation of mature glucagon by proteolysis of the precursor proglucagon.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/14505"^^xsd:anyURI) -AnnotationAssertion( "krc") -AnnotationAssertion( "2017-11-08T19:31:42Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0120116") -AnnotationAssertion(rdfs:label "glucagon processing") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (positive regulation of collagen catabolic process) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that activates or increases the frequency, rate or extent of collagen catabolism. Collagen catabolism is the proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/15720"^^xsd:anyURI) -AnnotationAssertion( "krc") -AnnotationAssertion( "2018-05-11T16:31:42Z") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "positive regulation of collagen breakdown") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "positive regulation of collagen catabolism") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "positive regulation of collagen degradation") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "up regulation of collagen catabolic process") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "up-regulation of collagen catabolic process") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "upregulation of collagen catabolic process") -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "activation of collagen catabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0120158") -AnnotationAssertion(rdfs:label "positive regulation of collagen catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (steroid hormone biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:krc") Annotation( "GOC:nln") "The chemical reactions and pathways resulting in the formation of any steroid hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/16000"^^xsd:anyURI) -AnnotationAssertion( "krc") -AnnotationAssertion( "2019-05-20T22:34:00Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0120178") -AnnotationAssertion(rdfs:label "steroid hormone biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of protein localization to chromatin) - -AnnotationAssertion(Annotation( "PMID:20889714") Annotation( "PMID:29899453") "Any process that stops, prevents, or reduces the frequency, rate or extent of protein localization to chromatin.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/16012"^^xsd:anyURI) -AnnotationAssertion( "krc") -AnnotationAssertion( "2018-07-14T00:19:32Z") -AnnotationAssertion(Annotation( "GOC:krc") "negative regulation of protein localisation to chromatin") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0120186") -AnnotationAssertion(rdfs:label "negative regulation of protein localization to chromatin") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of protein localization to chromatin) - -AnnotationAssertion(Annotation( "PMID:20889714") Annotation( "PMID:29899453") "Any process that activates or increases the frequency, rate or extent of protein localization to chromatin.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/16012"^^xsd:anyURI) -AnnotationAssertion( "krc") -AnnotationAssertion( "2018-07-14T00:21:28Z") -AnnotationAssertion(Annotation( "GOC:krc") "positive regulation of protein localisation to chromatin") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0120187") -AnnotationAssertion(rdfs:label "positive regulation of protein localization to chromatin") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of bile acid secretion) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_miRNA") Annotation( "GOC:rph") Annotation( "PMID:22767443") "Any process that modulates the frequency, rate or extent of the controlled release of bile acid from a cell or a tissue.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/16040"^^xsd:anyURI) -AnnotationAssertion( "krc") -AnnotationAssertion( "2018-07-16T22:28:58Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0120188") -AnnotationAssertion(rdfs:label "regulation of bile acid secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of bile acid secretion) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_miRNA") Annotation( "GOC:rph") Annotation( "PMID:22767443") "Any process that activates or increases the frequency, rate or extent of the controlled release of bile acid from a cell or a tissue.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/16040"^^xsd:anyURI) -AnnotationAssertion( "krc") -AnnotationAssertion( "2018-07-16T22:36:17Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0120189") -AnnotationAssertion(rdfs:label "positive regulation of bile acid secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of bile acid secretion) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_miRNA") Annotation( "GOC:rph") Annotation( "PMID:22767443") "Any process that stops, prevents or reduces the frequency, rate or extent of the controlled release of bile acid from a cell or a tissue.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/16040"^^xsd:anyURI) -AnnotationAssertion( "krc") -AnnotationAssertion( "2018-07-16T22:38:34Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0120190") -AnnotationAssertion(rdfs:label "negative regulation of bile acid secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (tight junction assembly) - -AnnotationAssertion(Annotation( "GOC:rl") "A cellular process that results in the aggregation, arrangement and bonding together of a set of components to form a tight junction. A tight junction seals cells together in an epithelium in a way that prevents even small molecules from leaking from one side of the sheet to the other.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/16187"^^xsd:anyURI) -AnnotationAssertion( "krc") -AnnotationAssertion( "2018-08-14T22:48:05Z") -AnnotationAssertion(Annotation( "GOC:rl") "occluding cell junction assembly") -AnnotationAssertion(Annotation( "GOC:rl") "occluding junction assembly") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0120192") -AnnotationAssertion(rdfs:label "tight junction assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (tight junction organization) - -AnnotationAssertion(Annotation( "GOC:krc") Annotation( "GOC:rl") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a tight junction. A tight junction seals cells together in an epithelium in a way that prevents even small molecules from leaking from one side of the sheet to the other.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/16187"^^xsd:anyURI) -AnnotationAssertion( "krc") -AnnotationAssertion( "2018-08-14T23:05:40Z") -AnnotationAssertion(Annotation( "GOC:rl") "occluding cell junction organization") -AnnotationAssertion( "occluding junction organization") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0120193") -AnnotationAssertion(rdfs:label "tight junction organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (cone photoreceptor outer segment) - -AnnotationAssertion(Annotation( "GOC:krc") Annotation( "GOC:pde") Annotation( "PMID:19501669") Annotation( "PMID:26574505") Annotation( "PMID:6771304") "The outer segment of a vertebrate cone photoreceptor that contains membrane discs that are contiguous with the ciliary membrane and containing opsin photoreceptor proteins.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/17217"^^xsd:anyURI) -AnnotationAssertion( "krc") -AnnotationAssertion( "2019-05-07T22:23:28Z") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0120199") -AnnotationAssertion(rdfs:label "cone photoreceptor outer segment") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (rod photoreceptor outer segment) - -AnnotationAssertion(Annotation( "GOC:krc") Annotation( "GOC:pde") Annotation( "PMID:19501669") Annotation( "PMID:26574505") Annotation( "PMID:6771304") "The outer segment of a vertebrate rod photoreceptor that contains sealed membrane discs that are not connected to the ciliary membrane and containing rhodopsin photoreceptor proteins.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/17217"^^xsd:anyURI) -AnnotationAssertion( "krc") -AnnotationAssertion( "2019-05-07T22:47:20Z") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0120200") -AnnotationAssertion(rdfs:label "rod photoreceptor outer segment") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of blastocyst development) - -AnnotationAssertion(Annotation( "GOC:krc") Annotation( "PMID:29593216") "Any process that modulates the frequency, rate or extent of blastocyst development.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/18871"^^xsd:anyURI) -AnnotationAssertion( "krc") -AnnotationAssertion( "2020-02-17T19:59:20Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0120222") -AnnotationAssertion(rdfs:label "regulation of blastocyst development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (larynx morphogenesis) - -AnnotationAssertion(Annotation( "GOC:krc") Annotation( "PMID:28177282") "The process in which the larynx is generated and organized. The larynx is a continuation of the pharynx that is involved in breathing, sound production, and protecting the trachea against food aspiration.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/18924"^^xsd:anyURI) -AnnotationAssertion( "krc") -AnnotationAssertion( "2020-02-22T01:42:04Z") -AnnotationAssertion(Annotation( "GOC:krc") Annotation( "PMID:28177282") "laryngeal morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0120223") -AnnotationAssertion(rdfs:label "larynx morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (larynx development) - -AnnotationAssertion(Annotation( "GOC:krc") Annotation( "PMID:28177282") "The biological process whose specific outcome is the progression of a larynx from an initial condition to its mature state. This process begins with the formation of the larynx and ends with the mature structure. A larynx is a continuation of the pharynx that is involved in breathing, sound production, and protecting the trachea against food aspiration.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/18924"^^xsd:anyURI) -AnnotationAssertion( "krc") -AnnotationAssertion( "2020-02-24T17:13:10Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0120224") -AnnotationAssertion(rdfs:label "larynx development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (protein localization to motile cilium) - -AnnotationAssertion(Annotation( "GOC:krc") Annotation( "PMID:27486780") "A process in which a protein is transported to, or maintained in, a location within a motile cilium.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/19588"^^xsd:anyURI) -AnnotationAssertion( "krc") -AnnotationAssertion( "2020-06-05T23:43:04Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "protein localization to nonmotile primary cilium") -AnnotationAssertion( "GO:0120229") -AnnotationAssertion(rdfs:label "protein localization to motile cilium") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (hydrocarbon biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:krc") Annotation( "Wikipedia:Hydrocarbon") "The chemical reactions and pathways resulting in the formation of a hydrocarbon, a compound consisting of carbon and hydrogen only.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/19842"^^xsd:anyURI) -AnnotationAssertion( "krc") -AnnotationAssertion( "2020-09-02T20:35:53Z") -AnnotationAssertion(Annotation( "GOC:krc") "hydrocarbon anabolism") -AnnotationAssertion(Annotation( "GOC:krc") "hydrocarbon biosynthesis") -AnnotationAssertion(Annotation( "GOC:krc") "hydrocarbon formation") -AnnotationAssertion(Annotation( "GOC:krc") "hydrocarbon synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0120251") -AnnotationAssertion(rdfs:label "hydrocarbon biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (hydrocarbon metabolic process) - -AnnotationAssertion(Annotation( "GOC:krc") Annotation( "Wikipedia:Hydrocarbon") "The chemical reactions and pathways involving a hydrocarbon, a compound consisting of carbon and hydrogen only.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/19842"^^xsd:anyURI) -AnnotationAssertion( "krc") -AnnotationAssertion( "2020-09-02T20:47:28Z") -AnnotationAssertion(Annotation( "GOC:krc") "hydrocarbon metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0120252") -AnnotationAssertion(rdfs:label "hydrocarbon metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (hydrocarbon catabolic process) - -AnnotationAssertion(Annotation( "GOC:krc") Annotation( "Wikipedia:Hydrocarbon") "The chemical reactions and pathways resulting in the breakdown of a hydrocarbon, a compound consisting of carbon and hydrogen only.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/19842"^^xsd:anyURI) -AnnotationAssertion( "krc") -AnnotationAssertion( "2020-09-02T20:58:57Z") -AnnotationAssertion(Annotation( "GOC:krc") "hydrocarbon breakdown") -AnnotationAssertion(Annotation( "GOC:krc") "hydrocarbon catabolism") -AnnotationAssertion(Annotation( "GOC:krc") "hydrocarbon degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0120253") -AnnotationAssertion(rdfs:label "hydrocarbon catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (olefinic compound metabolic process) - -AnnotationAssertion(Annotation( "GOC:krc") "The chemical reactions and pathways involving an olefinic compound, any compound which contains a carbon-carbon double bond (aka C=C).") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/19936"^^xsd:anyURI) -AnnotationAssertion( "krc") -AnnotationAssertion( "2020-09-02T23:13:44Z") -AnnotationAssertion( "alkene substituted compound metabolic process") -AnnotationAssertion( "alkene substituted compound metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0120254") -AnnotationAssertion(rdfs:label "olefinic compound metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (olefinic compound biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:krc") "The chemical reactions and pathways resulting in the formation of an olefinic compound, any compound which contains a carbon-carbon double bond (aka C=C).") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/19936"^^xsd:anyURI) -AnnotationAssertion( "krc") -AnnotationAssertion( "2020-09-02T23:30:20Z") -AnnotationAssertion(Annotation( "GOC:krc") "alkene substituted compound anabolic process") -AnnotationAssertion(Annotation( "GOC:krc") "alkene substituted compound anabolism") -AnnotationAssertion(Annotation( "GOC:krc") "alkene substituted compound biosynthesis") -AnnotationAssertion(Annotation( "GOC:krc") "alkene substituted compound biosynthetic process") -AnnotationAssertion(Annotation( "GOC:krc") "alkene substituted compound synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0120255") -AnnotationAssertion(rdfs:label "olefinic compound biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (olefinic compound catabolic process) - -AnnotationAssertion(Annotation( "GOC:krc") "The chemical reactions and pathways resulting in the breakdown of an olefinic compound, any compound which contains a carbon-carbon double bond (aka C=C).") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/19936"^^xsd:anyURI) -AnnotationAssertion( "krc") -AnnotationAssertion( "2020-09-02T23:30:41Z") -AnnotationAssertion(Annotation( "GOC:krc") "alkene substituted compound breakdown") -AnnotationAssertion(Annotation( "GOC:krc") "alkene substituted compound catabolic process") -AnnotationAssertion(Annotation( "GOC:krc") "alkene substituted compound catabolism") -AnnotationAssertion(Annotation( "GOC:krc") "alkene substituted compound degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0120256") -AnnotationAssertion(rdfs:label "olefinic compound catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cerebral blood circulation) - -AnnotationAssertion(Annotation( "GOC:krc") Annotation( "PMID:25397684") "The flow of blood through the network of arteries and veins supplying the cerebrum, enabling the transport of nutrients to the tissues and the removal of waste products.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/20107"^^xsd:anyURI) -AnnotationAssertion( "krc") -AnnotationAssertion( "2020-10-20T19:13:51Z") -AnnotationAssertion( "cerebrum blood circulation") -AnnotationAssertion( "telencephelon blood circulation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0120275") -AnnotationAssertion(rdfs:label "cerebral blood circulation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of cerebral blood circulation) - -AnnotationAssertion(Annotation( "GOC:krc") Annotation( "PMID:25397684") "Any process that modulates the frequency, rate or extent of cerebral blood circulation.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/20107"^^xsd:anyURI) -AnnotationAssertion( "krc") -AnnotationAssertion( "2020-10-21T06:52:22Z") -AnnotationAssertion( "regulation of cerebrum blood circulation") -AnnotationAssertion( "regulation of telencephalon blood circulation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0120276") -AnnotationAssertion(rdfs:label "regulation of cerebral blood circulation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of cerebral blood circulation) - -AnnotationAssertion(Annotation( "GOC:krc") Annotation( "PMID:25397684") "Any process that activates or increases the frequency, rate or extent of cerebral blood circulation.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/20107"^^xsd:anyURI) -AnnotationAssertion( "krc") -AnnotationAssertion( "2020-10-21T06:55:42Z") -AnnotationAssertion( "positive regulation of cerebrum blood circulation") -AnnotationAssertion( "positive regulation of telencephalon blood circulation") -AnnotationAssertion( "up regulation of cerebral blood circulation") -AnnotationAssertion( "up-regulation of cerebral blood circulation") -AnnotationAssertion( "upregulation of cerebral blood circulation") -AnnotationAssertion( "activation of cerebral blood circulation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0120277") -AnnotationAssertion(rdfs:label "positive regulation of cerebral blood circulation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of cerebral blood circulation) - -AnnotationAssertion(Annotation( "GOC:krc") Annotation( "PMID:25397684") "Any process that stops, prevents or reduces the frequency, rate or extent of cerebral blood circulation.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/20107"^^xsd:anyURI) -AnnotationAssertion( "krc") -AnnotationAssertion( "2020-10-21T07:02:05Z") -AnnotationAssertion( "down regulation of cerebral blood circulation") -AnnotationAssertion( "down-regulation of cerebral blood circulation") -AnnotationAssertion( "downregulation of cerebral blood circulation") -AnnotationAssertion( "negative regulation of cerebrum blood circulation") -AnnotationAssertion( "negative regulation of telencephalon blood circulation") -AnnotationAssertion( "inhibition of cerebral blood circulation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0120278") -AnnotationAssertion(rdfs:label "negative regulation of cerebral blood circulation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of pigmentation) - -AnnotationAssertion(Annotation( "GOC:krc") "Any process that modulates the frequency, rate or extent of the deposition or modulates the distribution of coloring matter in an organism.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/20524"^^xsd:anyURI) -AnnotationAssertion( "krc") -AnnotationAssertion( "2021-02-09T19:37:35Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0120305") -AnnotationAssertion(rdfs:label "regulation of pigmentation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (sperm flagellum assembly) - -AnnotationAssertion(Annotation( "GOC:krc") Annotation( "PMID:32791035") "The assembly and organization of the sperm flagellum, the microtubule-based axoneme and associated structures that are part of a sperm flagellum (or cilium).") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/21361"^^xsd:anyURI) -AnnotationAssertion( "krc") -AnnotationAssertion( "2021-04-29T01:27:27Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0120316") -AnnotationAssertion(rdfs:label "sperm flagellum assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (endothelial tube formation) - -AnnotationAssertion(Annotation( "GOC:sl") Annotation( "PMID:23239824") "The developmental process pertaining to the initial formation of an endothelial tube.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/22302"^^xsd:anyURI) -AnnotationAssertion( "krc") -AnnotationAssertion( "2022-05-25T16:17:59Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0120331") -AnnotationAssertion(rdfs:label "endothelial tube formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) # Class: (meiotic nuclear division) @@ -114874,450 +27927,6 @@ AnnotationAssertion( "GO:0140013") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "meiotic nuclear division") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (mitotic nuclear division) - -AnnotationAssertion(Annotation( "ISBN:0198547684") "A mitotic cell cycle process comprising the steps by which the nucleus of a eukaryotic cell divides; the process involves condensation of chromosomal DNA into a highly compacted form. Canonically, mitosis produces two daughter nuclei whose chromosome complement is identical to that of the mother cell.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/19910"^^xsd:anyURI) -AnnotationAssertion( "pg") -AnnotationAssertion( "2017-03-23T14:44:23Z") -AnnotationAssertion( "mitosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0140014") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "mitotic nuclear division") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (exocytic process) - -AnnotationAssertion(Annotation( "Wikipedia:Exocytosis") "The cellular processes that contribute to exocytosis.") -AnnotationAssertion( "pg") -AnnotationAssertion( "2017-05-15T13:20:45Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0140029") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "exocytic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (organelle localization by membrane tethering) - -AnnotationAssertion(Annotation( "PMID:27875684") "The process by which an organelle membrane interacts with another membrane via molecular tethers that physically bridge the two membranes and attach them to each other.") -AnnotationAssertion( "pg") -AnnotationAssertion( "2017-06-27T09:58:51Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0140056") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "organelle localization by membrane tethering") -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of lipoprotein transport) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_miRNA") Annotation( "GOC:RPH") Annotation( "PMID:26501192") "Any process that controls lipoprotein transport.") -AnnotationAssertion( "pg") -AnnotationAssertion( "2017-07-21T15:35:47Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0140075") -AnnotationAssertion(rdfs:label "regulation of lipoprotein transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of lipoprotein transport) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_miRNA") Annotation( "GOC:RPH") Annotation( "PMID:26501192") "Any process that stops, prevents or reduces the frequency, rate or extent of lipoprotein transport.") -AnnotationAssertion( "pg") -AnnotationAssertion( "2017-07-21T15:39:50Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0140076") -AnnotationAssertion(rdfs:label "negative regulation of lipoprotein transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of lipoprotein transport) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_miRNA") Annotation( "GOC:RPH") Annotation( "PMID:26501192") "Any process that activates or increases the rate or extent of lipoprotein transport.") -AnnotationAssertion( "pg") -AnnotationAssertion( "2017-07-21T15:41:54Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0140077") -AnnotationAssertion(rdfs:label "positive regulation of lipoprotein transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (catalytic activity, acting on a protein) - -AnnotationAssertion(Annotation( "GOC:molecular_function_refactoring") Annotation( "GOC:pdt") "Catalytic activity that acts to modify a protein.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/14225"^^xsd:anyURI) -AnnotationAssertion( "pg") -AnnotationAssertion( "2017-09-14T10:32:59Z") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0140096") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "catalytic activity, acting on a protein") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (catalytic activity, acting on DNA) - -AnnotationAssertion(Annotation( "GOC:molecular_function_refactoring") Annotation( "GOC:pdt") "Catalytic activity that acts to modify DNA.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/14225"^^xsd:anyURI) -AnnotationAssertion( "pg") -AnnotationAssertion( "2017-09-14T12:03:51Z") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0140097") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "catalytic activity, acting on DNA") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (catalytic activity, acting on RNA) - -AnnotationAssertion(Annotation( "GOC:molecular_function_refactoring") Annotation( "GOC:pdt") "Catalytic activity that acts to modify RNA, driven by ATP hydrolysis.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/14225"^^xsd:anyURI) -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/21612"^^xsd:anyURI) -AnnotationAssertion( "pg") -AnnotationAssertion( "2017-09-14T12:05:21Z") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0140098") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "catalytic activity, acting on RNA") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (catalytic activity, acting on a glycoprotein) - -AnnotationAssertion(Annotation( "GOC:molecular_function_refactoring") Annotation( "GOC:pdt") "Catalysis of a biochemical reaction at physiological temperatures in which one of the substrates is a glycoprotein.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/14225"^^xsd:anyURI) -AnnotationAssertion( "pg") -AnnotationAssertion( "2017-09-15T19:27:54Z") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0140103") -AnnotationAssertion(rdfs:label "catalytic activity, acting on a glycoprotein") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (extracellular vesicle biogenesis) - -AnnotationAssertion(Annotation( "PMID:28736435") "The assembly and secretion a set of components to form an extracellular vesicule, a membrane-bounded vesicle that is released into the extracellular region. Extracellular vesicles include exosomes, microvesicles and apoptotic bodies, based on the mechanism by which they are released from cells and differentiated based on their size and content.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/14256"^^xsd:anyURI) -AnnotationAssertion( "pg") -AnnotationAssertion( "2017-10-23T11:53:42Z") -AnnotationAssertion( "extracellular vesicle assembly") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0140112") -AnnotationAssertion(rdfs:label "extracellular vesicle biogenesis") -SubClassOf( ) - -# Class: (export across plasma membrane) - -AnnotationAssertion(Annotation( "GOC:pg") "The directed movement of some substance from inside of a cell, across the plasma membrane and into the extracellular region.") -AnnotationAssertion( "pg") -AnnotationAssertion( "2017-10-24T14:38:16Z") -AnnotationAssertion( "efflux") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0140115") -AnnotationAssertion(rdfs:label "export across plasma membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of lymphocyte chemotaxis) - -AnnotationAssertion(Annotation( "PMID:19255442") "Any process that activates or increases the frequency, rate or extent of lymphocyte chemotaxis.") -AnnotationAssertion( "pg") -AnnotationAssertion( "2017-11-02T10:26:40Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0140131") -AnnotationAssertion(rdfs:label "positive regulation of lymphocyte chemotaxis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (calcium ion import into vacuole) - -AnnotationAssertion(Annotation( "GOC:vw") Annotation( "PMID:8628289") "The directed movement of calcium cations into the vacuole across the vacuolar membrane.") -AnnotationAssertion( "pg") -AnnotationAssertion( "2017-12-13T15:15:29Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0140146") -AnnotationAssertion(rdfs:label "calcium ion import into vacuole") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (ammonium import across plasma membrane) - -AnnotationAssertion(Annotation( "GOC:vw") Annotation( "PMID:16999738") "The directed movement of an ammonium ion from outside of a cell, across the plasma membrane and into the cytosol.") -AnnotationAssertion( "pg") -AnnotationAssertion( "2018-01-26T12:39:56Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0140157") -AnnotationAssertion(rdfs:label "ammonium import across plasma membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (anterograde axonal transport of neurotransmitter receptor complex) - -AnnotationAssertion(Annotation( "PMID:28680963") "The directed movement of a neurotransmitter receptor complex along microtubules from the cell body toward the cell periphery in nerve cell axons.") -AnnotationAssertion( "pg") -AnnotationAssertion( "2018-07-09T09:41:37Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0140231") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "anterograde axonal transport of neurotransmitter receptor complex") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (translation at presynapse) - -AnnotationAssertion(Annotation( "PMID:27321671") "Translation that occurs at the presynapse.") -AnnotationAssertion( "https://github.com/geneontology/synapse/issues/216"^^xsd:anyURI) -AnnotationAssertion( "pg") -AnnotationAssertion( "2018-07-13T13:00:33Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0140236") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.") -AnnotationAssertion(rdfs:label "translation at presynapse") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (translation at presynapse, modulating chemical synaptic transmission) - -AnnotationAssertion(Annotation( "PMID:27321671") "Translation that occurs at the presynapse, and that modulates chemical synaptic transmission.") -AnnotationAssertion( "https://github.com/geneontology/synapse/issues/216"^^xsd:anyURI) -AnnotationAssertion( "pg") -AnnotationAssertion( "2018-07-13T13:07:23Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0140237") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.") -AnnotationAssertion(rdfs:label "translation at presynapse, modulating chemical synaptic transmission") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (presynaptic endocytosis) - -AnnotationAssertion(Annotation( "PMID:24719103") "A vesicle-mediated transport process in which the presynapse take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle.") -AnnotationAssertion( "https://github.com/geneontology/synapse/issues/230"^^xsd:anyURI) -AnnotationAssertion( "pg") -AnnotationAssertion( "2018-07-15T07:33:55Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0140238") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.") -AnnotationAssertion(rdfs:label "presynaptic endocytosis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (postsynaptic endocytosis) - -AnnotationAssertion(Annotation( "PMID:12839988") "A vesicle-mediated transport process in which the postsynapse take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle.") -AnnotationAssertion( "https://github.com/geneontology/synapse/issues/230"^^xsd:anyURI) -AnnotationAssertion( "pg") -AnnotationAssertion( "2018-07-15T07:38:27Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0140239") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.") -AnnotationAssertion(rdfs:label "postsynaptic endocytosis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (translation at synapse) - -AnnotationAssertion(Annotation( "PMID:23083742") "Translation that occurs at the synapse.") -AnnotationAssertion( "https://github.com/geneontology/synapse/issues/210"^^xsd:anyURI) -AnnotationAssertion( "pg") -AnnotationAssertion( "2018-07-15T09:23:12Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0140241") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.") -AnnotationAssertion(rdfs:label "translation at synapse") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - -# Class: (translation at postsynapse) - -AnnotationAssertion(Annotation( "PMID:20427644") "Translation that occurs at the postsynapse.") -AnnotationAssertion( "https://github.com/geneontology/synapse/issues/210"^^xsd:anyURI) -AnnotationAssertion( "pg") -AnnotationAssertion( "2018-07-15T09:26:27Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0140242") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.") -AnnotationAssertion(rdfs:label "translation at postsynapse") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of translation at synapse) - -AnnotationAssertion(Annotation( "PMID:20427644") "Any process that regulates translation occurring at the synapse.") -AnnotationAssertion( "https://github.com/geneontology/synapse/issues/210"^^xsd:anyURI) -AnnotationAssertion( "pg") -AnnotationAssertion( "2018-07-15T09:38:26Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0140243") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.") -AnnotationAssertion(rdfs:label "regulation of translation at synapse") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - -# Class: (regulation of translation at presynapse) - -AnnotationAssertion(Annotation( "PMID:20427644") "Any process that regulates translation occurring at the presynapse.") -AnnotationAssertion( "https://github.com/geneontology/synapse/issues/210"^^xsd:anyURI) -AnnotationAssertion( "pg") -AnnotationAssertion( "2018-07-15T09:38:33Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0140244") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.") -AnnotationAssertion(rdfs:label "regulation of translation at presynapse") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (regulation of translation at postsynapse) - -AnnotationAssertion(Annotation( "PMID:20427644") "Any process that regulates translation occurring at the postsynapse.") -AnnotationAssertion( "https://github.com/geneontology/synapse/issues/210"^^xsd:anyURI) -AnnotationAssertion( "pg") -AnnotationAssertion( "2018-07-15T09:38:54Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0140245") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.") -AnnotationAssertion(rdfs:label "regulation of translation at postsynapse") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (protein catabolic process at synapse) - -AnnotationAssertion(Annotation( "PMID:17062563") "The chemical reactions and pathways resulting in the breakdown of a protein at a synapse.") -AnnotationAssertion( "https://github.com/geneontology/synapse/issues/210"^^xsd:anyURI) -AnnotationAssertion( "pg") -AnnotationAssertion( "2018-07-15T10:12:51Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0140246") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.") -AnnotationAssertion(rdfs:label "protein catabolic process at synapse") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - -# Class: (protein catabolic process at presynapse) - -AnnotationAssertion(Annotation( "PMID:27764673") "The chemical reactions and pathways resulting in the breakdown of a protein at a presynapse.") -AnnotationAssertion( "https://github.com/geneontology/synapse/issues/204"^^xsd:anyURI) -AnnotationAssertion( "pg") -AnnotationAssertion( "2018-07-15T10:23:49Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0140247") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.") -AnnotationAssertion(rdfs:label "protein catabolic process at presynapse") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (protein catabolic process at postsynapse) - -AnnotationAssertion(Annotation( "PMID:17062563") "The chemical reactions and pathways resulting in the breakdown of a protein at a postsynapse.") -AnnotationAssertion( "https://github.com/geneontology/synapse/issues/204"^^xsd:anyURI) -AnnotationAssertion( "pg") -AnnotationAssertion( "2018-07-15T10:25:04Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0140249") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.") -AnnotationAssertion(rdfs:label "protein catabolic process at postsynapse") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (regulation protein catabolic process at synapse) - -AnnotationAssertion(Annotation( "PMID:23083742") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein at the synapse.") -AnnotationAssertion( "https://github.com/geneontology/synapse/issues/204"^^xsd:anyURI) -AnnotationAssertion( "pg") -AnnotationAssertion( "2018-07-15T10:34:56Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0140250") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.") -AnnotationAssertion(rdfs:label "regulation protein catabolic process at synapse") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - -# Class: (regulation protein catabolic process at presynapse) - -AnnotationAssertion(Annotation( "PMID:27764673") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein at the presynapse.") -AnnotationAssertion( "https://github.com/geneontology/synapse/issues/204"^^xsd:anyURI) -AnnotationAssertion( "pg") -AnnotationAssertion( "2018-07-15T10:35:39Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0140251") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.") -AnnotationAssertion(rdfs:label "regulation protein catabolic process at presynapse") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (regulation protein catabolic process at postsynapse) - -AnnotationAssertion(Annotation( "PMID:17062563") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein at the postsynapse.") -AnnotationAssertion( "https://github.com/geneontology/synapse/issues/204"^^xsd:anyURI) -AnnotationAssertion( "pg") -AnnotationAssertion( "2018-07-15T10:35:56Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0140252") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.") -AnnotationAssertion(rdfs:label "regulation protein catabolic process at postsynapse") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (cell-cell fusion) - -AnnotationAssertion(Annotation( "Wikipedia:Cell_fusion") "A cellular process in which two or more cells combine together, their plasma membrane fusing, producing a single cell. In some cases, nuclei fuse, producing a polyploid cell, while in other cases, nuclei remain separate, producing a syncytium.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/15939"^^xsd:anyURI) -AnnotationAssertion( "pg") -AnnotationAssertion( "2018-08-13T18:38:18Z") -AnnotationAssertion( "cell fusion") -AnnotationAssertion( "cell cell fusion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0140253") -AnnotationAssertion(rdfs:label "cell-cell fusion") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (hexose import across plasma membrane) - -AnnotationAssertion(Annotation( "PMID:10735857") "The directed movement of hexose from outside of a cell, across the plasma membrane and into the cytosol.") -AnnotationAssertion( "pg") -AnnotationAssertion( "2018-10-01T08:49:49Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0140271") -AnnotationAssertion(rdfs:label "hexose import across plasma membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (DNA-binding transcription factor binding) - -AnnotationAssertion(Annotation( "GOC:txnOH-2018") "Binding to a DNA-binding transcription factor, a protein that interacts with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/19354"^^xsd:anyURI) -AnnotationAssertion( "pg") -AnnotationAssertion( "2018-11-28T12:48:20Z") -AnnotationAssertion( "GO:0001107") -AnnotationAssertion( "GO:0033613") -AnnotationAssertion( "GO:0070491") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "activating transcription factor binding") -AnnotationAssertion( "repressing transcription factor binding") -AnnotationAssertion( "transcription activator binding") -AnnotationAssertion( "GO:0140297") -AnnotationAssertion(rdfs:label "DNA-binding transcription factor binding") -SubClassOf( ) - -# Class: (protein transporter activity) - -AnnotationAssertion(Annotation( "PMID:18706423") "Directly binding to a specific protein and delivering it to a specific cellular location.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/17073"^^xsd:anyURI) -AnnotationAssertion( "pg") -AnnotationAssertion( "2019-04-01T10:41:38Z") -AnnotationAssertion(Annotation(rdfs:label "iRHOM2 transports ADAM17 from ER to the Golgi-network") "Reactome:R-HSA-9662747") -AnnotationAssertion(Annotation(rdfs:label "iRHOM2 transports ADAM17:Zn2+ from Golgi to the plasma membrane") "Reactome:R-HSA-9662818") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "protein carrier activity") -AnnotationAssertion( "protein transport chaperone") -AnnotationAssertion( "GO:0140318") -AnnotationAssertion(rdfs:comment "Examples of protein carriers include the soluble TIM chaperone complexes of S. cerevisiae Tim9-Tim10 and Tim8-Tim13, that provide a shuttle system between TOM and the membrane insertases TIM22 and SAM and, thus, ensure that precursors are kept in a translocation-competent conformation.") -AnnotationAssertion(rdfs:label "protein transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (export from cell) @@ -115328,2580 +27937,8 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0140352") AnnotationAssertion(rdfs:label "export from cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (lipid export from cell) - -AnnotationAssertion(Annotation( "GOC:pg") "The directed movement of a lipid from a cell, into the extracellular region.") -AnnotationAssertion( "pg") -AnnotationAssertion( "2019-05-22T11:33:07Z") -AnnotationAssertion( "lipid efflux") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0140353") -AnnotationAssertion(rdfs:label "lipid export from cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (lipid import into cell) - -AnnotationAssertion(Annotation( "GOC:pg") "The directed movement of a lipid from outside of a cell into a cell. This may occur via transport across the plasma membrane or via endocytosis.") -AnnotationAssertion( "pg") -AnnotationAssertion( "2019-05-22T11:38:15Z") -AnnotationAssertion( "lipid uptake") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0140354") -AnnotationAssertion(rdfs:label "lipid import into cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (immune receptor activity) - -AnnotationAssertion(Annotation( "PMID:31415752") Annotation( "Wikipedia:Immune_receptor") "Receiving a signal and transmitting it in a cell to initiate an immune response.") -AnnotationAssertion( "pg") -AnnotationAssertion( "2019-10-18T14:11:15Z") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0140375") -AnnotationAssertion(rdfs:label "immune receptor activity") -SubClassOf( ) - -# Class: (signaling receptor ligand precursor processing) - -AnnotationAssertion(Annotation( "PMID:29247995") "The cleavage of a peptide bond in a precursor form of a signaling receptor ligand, resulting in the mature (active) form of the ligand.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/19216"^^xsd:anyURI) -AnnotationAssertion( "pg") -AnnotationAssertion( "2020-04-03T13:30:04Z") -AnnotationAssertion( "GO:0035638") -AnnotationAssertion(Annotation( "GOC:bf") "ligand maturation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "signal maturation") -AnnotationAssertion( "GO:0140448") -AnnotationAssertion(rdfs:label "signaling receptor ligand precursor processing") -SubClassOf( ) - -# Class: (nuclear protein-containing complex) - -AnnotationAssertion(Annotation( "GOC:pg") "A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together in the nucleus.") -AnnotationAssertion( "pg") -AnnotationAssertion( "2020-09-09T05:12:38Z") -AnnotationAssertion( "nuclear complex") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0140513") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "nuclear protein-containing complex") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (vacuole fission) - -AnnotationAssertion(Annotation( "PMID:19643199") "The division of a vacuole within a cell to form two or more separate vacuoles.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/20639"^^xsd:anyURI) -AnnotationAssertion( "pg") -AnnotationAssertion( "2021-01-04T10:17:58Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0140572") -AnnotationAssertion(rdfs:label "vacuole fission") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (catalytic activity, acting on a nucleic acid) - -AnnotationAssertion(Annotation( "GOC:pg") "Catalytic activity that acts to modify a nucleic acid.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/21402"^^xsd:anyURI) -AnnotationAssertion( "pg") -AnnotationAssertion( "2021-05-11T06:31:07Z") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0140640") -AnnotationAssertion(rdfs:label "catalytic activity, acting on a nucleic acid") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (radial glia-guided pyramidal neuron migration) - -AnnotationAssertion(Annotation( "PMID:3760547") "The radial migration of a pyramidal neuron along radial glial cells.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/21476"^^xsd:anyURI) -AnnotationAssertion( "pg") -AnnotationAssertion( "2021-05-25T12:48:12Z") -AnnotationAssertion( "radial glia-dependent neuronal migration") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0140650") -AnnotationAssertion(rdfs:label "radial glia-guided pyramidal neuron migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (non-membrane-bounded organelle assembly) - -AnnotationAssertion(Annotation( "PMID:28225081") "The aggregation, arrangement and bonding together of a set of components to form a non-membrane-bounded organelle.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/21939"^^xsd:anyURI) -AnnotationAssertion( "pg") -AnnotationAssertion( "2021-08-09T15:30:06Z") -AnnotationAssertion( "non-membrane-bounded organelle formation") -AnnotationAssertion( "non-membrane-enclosed organelle assembly") -AnnotationAssertion( "non-membrane-enclosed organelle formation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0140694") -AnnotationAssertion(rdfs:label "non-membrane-bounded organelle assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (ammonium excretion) - -AnnotationAssertion(Annotation( "PMID:25740900") "The elimination of ammonium ions from an excretory cell.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/22368"^^xsd:anyURI) -AnnotationAssertion( "pg") -AnnotationAssertion( "2021-11-24T17:55:51Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "ammonia excretion") -AnnotationAssertion( "GO:0140734") -AnnotationAssertion(rdfs:label "ammonium excretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cytosol to Golgi apparatus transport) - -AnnotationAssertion(Annotation( "PMID:28373556") "The directed movement of substances from the cytosol into the Golgi apparatus of a cell.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/21524"^^xsd:anyURI) -AnnotationAssertion( "pg") -AnnotationAssertion( "2022-05-16T06:59:22Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0140820") -AnnotationAssertion(rdfs:label "cytosol to Golgi apparatus transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (cellular detoxification of metal ion) - -AnnotationAssertion(Annotation( "PMID:26729300") Annotation( "PMID:33046888") Annotation( "PMID:34442707") "Any process carried out at the cellular level that reduces or removes the toxicity of a metal ion.") -AnnotationAssertion( "pg") -AnnotationAssertion( "2022-12-07T15:35:18Z") -AnnotationAssertion( "cellular detoxification of metal cation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0140961") -AnnotationAssertion(rdfs:label "cellular detoxification of metal ion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (multicellular organismal-level chemical homeostasis) - -AnnotationAssertion(Annotation( "GOC:curators") "A homeostatic process involved in the maintenance of a steady state level of a chemical within extracellular body fluids, such as blood, xylem or phloem, of a multicellular organism. This is distinct from maintenance of cellular homeostasis, which occurs within a cell.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/24554"^^xsd:anyURI) -AnnotationAssertion( "pg") -AnnotationAssertion( "2022-12-12T09:11:06Z") -AnnotationAssertion( "multicellular organism level chemical homeostasis") -AnnotationAssertion( "organismal level chemical homeostasis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0140962") -AnnotationAssertion(rdfs:label "multicellular organismal-level chemical homeostasis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (intracellular nucleotide homeostasis) - -AnnotationAssertion(Annotation( "PMID:23416111") Annotation( "PMID:34880500") "A homeostatic process involved in the maintenance of a steady state level of nucleotides within a cell.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/24665"^^xsd:anyURI) -AnnotationAssertion( "pg") -AnnotationAssertion( "2023-01-10T14:13:19Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0140979") -AnnotationAssertion(rdfs:label "intracellular nucleotide homeostasis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (intracellular nucleoside homeostasis) - -AnnotationAssertion(Annotation( "PMID:23416111") Annotation( "PMID:34880500") "A homeostatic process involved in the maintenance of a steady state level of nucleosides within a cell.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/24665"^^xsd:anyURI) -AnnotationAssertion( "pg") -AnnotationAssertion( "2023-01-10T14:14:42Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0140980") -AnnotationAssertion(rdfs:label "intracellular nucleoside homeostasis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (intracellular nitrogen homeostasis) - -AnnotationAssertion(Annotation( "GOC:tb") "A homeostatic process involved in the maintenance of a steady state level of nitrogen within a cell.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/25558"^^xsd:anyURI) -AnnotationAssertion( "pg") -AnnotationAssertion( "2023-06-15T08:56:16Z") -AnnotationAssertion( "cellular nitrogen homeostasis") -AnnotationAssertion( "nitrogen homeostasis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0141067") -AnnotationAssertion(rdfs:label "intracellular nitrogen homeostasis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of protein localization to lysosome) - -AnnotationAssertion(Annotation( "GOC:aruk") Annotation( "GOC:bc") Annotation( "PMID:24305806") "Any process that modulates the frequency, rate or extent of protein localization to lysosome.") -AnnotationAssertion( "bc") -AnnotationAssertion( "2018-02-06T17:07:03Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0150031") -AnnotationAssertion(rdfs:label "regulation of protein localization to lysosome") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of protein localization to lysosome) - -AnnotationAssertion(Annotation( "GOC:aruk") Annotation( "GOC:bc") "Any process that activates or increases the frequency, rate or extent of protein localization to lysosome.") -AnnotationAssertion( "bc") -AnnotationAssertion( "2018-02-06T17:11:02Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0150032") -AnnotationAssertion(rdfs:label "positive regulation of protein localization to lysosome") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of protein localization to lysosome) - -AnnotationAssertion(Annotation( "GOC:aruk") Annotation( "GOC:bc") Annotation( "PMID:24305806") "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to lysosome.") -AnnotationAssertion( "bc") -AnnotationAssertion( "2018-02-06T17:14:16Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0150033") -AnnotationAssertion(rdfs:label "negative regulation of protein localization to lysosome") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of postsynapse assembly) - -AnnotationAssertion(Annotation( "GOC:aruk") Annotation( "GOC:bc") Annotation( "PMID:16394100") Annotation( "PMID:16672654") Annotation( "PMID:28185854") "Any process that modulates the frequency, rate or extent of postsynapse assembly, the aggregation, arrangement and bonding together of a set of components to form a postsynapse.") -AnnotationAssertion( "bc") -AnnotationAssertion( "2018-05-08T16:38:55Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0150052") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "regulation of postsynapse assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (visual system development) - -AnnotationAssertion(Annotation( "GOC:aruk") Annotation( "GOC:bc") Annotation( "GOC:krc") Annotation( "PMID:15004427") Annotation( "PMID:20647017") Annotation( "PMID:22632727") "The process whose specific outcome is the progression of the visual system over time, from its formation to the mature structure, including the eye, parts of the central nervous system (CNS) involved in processing of visual inputs, and connecting nerve pathways.") -AnnotationAssertion( "bc") -AnnotationAssertion( "2018-07-23T10:31:58Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "optic pathway development") -AnnotationAssertion( "visual pathway development") -AnnotationAssertion( "GO:0150063") -AnnotationAssertion(rdfs:label "visual system development") -SubClassOf( ) - -# Class: (neuroinflammatory response) - -AnnotationAssertion(Annotation( "GOC:aruk") Annotation( "GOC:bc") Annotation( "PMID:10981966") Annotation( "PMID:11099416") Annotation( "PMID:18164423") "The immediate defensive reaction by neural vertebrate tissue to infection or injury caused by chemical or physical agents.") -AnnotationAssertion( "bc") -AnnotationAssertion( "2018-07-26T12:25:34Z") -AnnotationAssertion( "nerve tissue inflammatory response") -AnnotationAssertion( "nervous tissue inflammatory response") -AnnotationAssertion( "neural tissue inflammatory response") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0150076") -AnnotationAssertion(rdfs:label "neuroinflammatory response") -SubClassOf( ) - -# Class: (regulation of neuroinflammatory response) - -AnnotationAssertion(Annotation( "GOC:aruk") Annotation( "GOC:bc") Annotation( "PMID:10981966") Annotation( "PMID:11099416") Annotation( "PMID:18164423") "Any process that modulates the frequency, rate or extent of neuroinflammatory response.") -AnnotationAssertion( "bc") -AnnotationAssertion( "2018-07-26T12:32:18Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0150077") -AnnotationAssertion(rdfs:label "regulation of neuroinflammatory response") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - -# Class: (positive regulation of neuroinflammatory response) - -AnnotationAssertion(Annotation( "GOC:aruk") Annotation( "GOC:bc") "Any process that activates or increases the frequency, rate or extent of neuroinflammatory response.") -AnnotationAssertion( "bc") -AnnotationAssertion( "2018-07-26T12:35:50Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0150078") -AnnotationAssertion(rdfs:label "positive regulation of neuroinflammatory response") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of neuroinflammatory response) - -AnnotationAssertion(Annotation( "GOC:aruk") Annotation( "GOC:bc") Annotation( "PMID:11099416") Annotation( "PMID:18164423") "Any process that stops, prevents or reduces the frequency, rate or extent of neuroinflammatory response.") -AnnotationAssertion( "bc") -AnnotationAssertion( "2018-07-26T12:38:08Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0150079") -AnnotationAssertion(rdfs:label "negative regulation of neuroinflammatory response") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (glial cell-neuron signaling) - -AnnotationAssertion(Annotation( "GOC:aruk") Annotation( "GOC:bc") Annotation( "PMID:14980203") Annotation( "PMID:16144764") Annotation( "PMID:16547515") Annotation( "PMID:18685038") Annotation( "PMID:27788368") Annotation( "PMID:9459440") "Cell-cell signaling that mediates the transfer of information from a glial cell to a neuron. This signaling has been shown to be mediated by various molecules, depending on which glial cells release them, and in which tissues the signaling occurs, e.g. microglial cell-derived nerve growth factor (NGF) in the retina, or microglial cell-derived superoxide ions in the cerebellum.") -AnnotationAssertion( "bc") -AnnotationAssertion( "2018-12-17T12:28:09Z") -AnnotationAssertion( "glia-neuron signaling") -AnnotationAssertion( "glia-neuron signalling") -AnnotationAssertion( "glia-neurone signaling") -AnnotationAssertion( "glia-neurone signalling") -AnnotationAssertion( "glial cell- neuron signalling") -AnnotationAssertion( "glial cell-neurone signalling") -AnnotationAssertion( "glial cell-neurone singaling") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0150098") -AnnotationAssertion(rdfs:label "glial cell-neuron signaling") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (neuron-glial cell signaling) - -AnnotationAssertion(Annotation( "GOC:aruk") Annotation( "GOC:bc") Annotation( "PMID:10195197") Annotation( "PMID:10196584") Annotation( "PMID:10377338") Annotation( "PMID:10493741") Annotation( "PMID:11356870") Annotation( "PMID:11399439") Annotation( "PMID:15252819") Annotation( "PMID:27788368") "Cell-cell signaling that mediates the transfer of information from a neuron to a glial cell. This signaling has been shown to be mediated by various molecules released by different types of neurons, e.g. glutamate, gamma-amino butyric acid (GABA), noradrenaline, acetylcholine, dopamine and adenosine.") -AnnotationAssertion( "bc") -AnnotationAssertion( "2018-12-17T12:30:12Z") -AnnotationAssertion( "neuron-glia signaling") -AnnotationAssertion( "neuron-glia signalling") -AnnotationAssertion( "neuron-glial cell signalling") -AnnotationAssertion( "neurone-glia signaling") -AnnotationAssertion( "neurone-glia signalling") -AnnotationAssertion( "neurone-glial cell signaling") -AnnotationAssertion( "neurone-glial cell signalling") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0150099") -AnnotationAssertion(rdfs:label "neuron-glial cell signaling") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of monocyte activation) - -AnnotationAssertion(Annotation( "GOC:aruk") Annotation( "PMID:15597323") "Any process that stops, prevents or reduces the frequency, rate or extent of monocyte activation.") -AnnotationAssertion( "bc") -AnnotationAssertion( "2019-04-26T20:01:24Z") -AnnotationAssertion( "repression of monocyte activation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0150102") -AnnotationAssertion(rdfs:label "negative regulation of monocyte activation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (transport across blood-brain barrier) - -AnnotationAssertion(Annotation( "GOC:aruk") Annotation( "GOC:bc") Annotation( "PMID:29377008") "The directed movement of substances (e.g. macromolecules, small molecules, ions) through the blood-brain barrier.") -AnnotationAssertion( "bc") -AnnotationAssertion( "2019-05-27T09:12:03Z") -AnnotationAssertion( "transport across BBB") -AnnotationAssertion( "transport across blood brain barrier") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0150104") -AnnotationAssertion(rdfs:label "transport across blood-brain barrier") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - -# Class: (protein localization to cell-cell junction) - -AnnotationAssertion(Annotation( "GOC:aruk") Annotation( "GOC:bc") Annotation( "PMID:26706435") "A process in which a protein is transported to, or maintained, in a location within a cell-cell junction.") -AnnotationAssertion( "bc") -AnnotationAssertion( "2019-06-11T11:00:18Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0150105") -AnnotationAssertion(rdfs:label "protein localization to cell-cell junction") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of protein localization to cell-cell junction) - -AnnotationAssertion(Annotation( "GOC:aruk") Annotation( "GOC:bc") Annotation( "PMID:26706435") "Any process that modulates the frequency, rate or extent of protein localization to cell-cell junction.") -AnnotationAssertion( "bc") -AnnotationAssertion( "2019-06-11T11:17:15Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0150106") -AnnotationAssertion(rdfs:label "regulation of protein localization to cell-cell junction") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of protein localization to cell-cell junction) - -AnnotationAssertion(Annotation( "GOC:aruk") Annotation( "GOC:bc") Annotation( "PMID:26706435") "Any process that activates or increases the frequency, rate or extent of protein localization to cell-cell junction.") -AnnotationAssertion( "bc") -AnnotationAssertion( "2019-06-11T11:23:58Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0150107") -AnnotationAssertion(rdfs:label "positive regulation of protein localization to cell-cell junction") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of transepithelial transport) - -AnnotationAssertion(Annotation( "GOC:aruk") Annotation( "PMID:27593915") "Any process that modulates the frequency, rate or extent of transepithelial transport.") -AnnotationAssertion( "bc") -AnnotationAssertion( "2019-09-15T07:16:49Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0150111") -AnnotationAssertion(rdfs:label "regulation of transepithelial transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of protein localization to cell-cell junction) - -AnnotationAssertion(Annotation( "GOC:aruk") Annotation( "GOC:bc") "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell-cell junction.") -AnnotationAssertion( "bc") -AnnotationAssertion( "2019-11-21T13:53:34Z") -AnnotationAssertion( "negative regulation of protein localisation to cell-cell junction") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0150119") -AnnotationAssertion(rdfs:label "negative regulation of protein localization to cell-cell junction") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cell junction disassembly) - -AnnotationAssertion(Annotation( "GOC:aruk") Annotation( "PMID:25490267") "The disaggregation of a cell junction into its constituent components.") -AnnotationAssertion( "bc") -AnnotationAssertion( "2019-12-08T11:12:13Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0150146") -AnnotationAssertion(rdfs:label "cell junction disassembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cell-cell junction disassembly) - -AnnotationAssertion(Annotation( "GOC:aruk") Annotation( "PMID:25490267") "The disaggregation of a cell-cell junction into its constituent components.") -AnnotationAssertion( "bc") -AnnotationAssertion( "2019-12-08T11:16:14Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0150147") -AnnotationAssertion(rdfs:label "cell-cell junction disassembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (transport across blood-cerebrospinal fluid barrier) - -AnnotationAssertion(Annotation( "GOC:aruk") Annotation( "GOC:bc") Annotation( "PMID:21349151") "The directed movement of substances (e.g. macromolecules, small molecules, ions) through the blood-cerebrospinal fluid barrier.") -AnnotationAssertion( "bc") -AnnotationAssertion( "2020-03-26T14:43:04Z") -AnnotationAssertion( "transport across BCSFB") -AnnotationAssertion( "transport across blood-CSF barrier") -AnnotationAssertion( "transport across blood/CSF barrier") -AnnotationAssertion( "transport across blood/cerebrospinal fluid barrier") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0150195") -AnnotationAssertion(rdfs:label "transport across blood-cerebrospinal fluid barrier") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of transport across blood-brain barrier) - -AnnotationAssertion(Annotation( "GOC:aruk") Annotation( "GOC:bc") Annotation( "PMID:29377008") Annotation( "PMID:30280653") "Any process that modulates the frequency, rate or extent of transport across the blood-brain barrier.") -AnnotationAssertion( "bc") -AnnotationAssertion( "2020-03-26T19:22:26Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0150200") -AnnotationAssertion(rdfs:label "regulation of transport across blood-brain barrier") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (positive regulation of transport across blood-brain barrier) - -AnnotationAssertion(Annotation( "GOC:aruk") Annotation( "GOC:bc") Annotation( "PMID:29377008") Annotation( "PMID:30280653") "Any process that activates or increases the frequency, rate or extent of transport across blood-brain barrier.") -AnnotationAssertion( "bc") -AnnotationAssertion( "2020-03-26T19:26:38Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0150201") -AnnotationAssertion(rdfs:label "positive regulation of transport across blood-brain barrier") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (negative regulation of transport across blood-brain barrier) - -AnnotationAssertion(Annotation( "GOC:aruk") Annotation( "GOC:bc") Annotation( "PMID:29377008") Annotation( "PMID:30280653") "Any process that stops, prevents or reduces the frequency, rate or extent of transport across blood-brain barrier.") -AnnotationAssertion( "bc") -AnnotationAssertion( "2020-03-26T19:28:51Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0150202") -AnnotationAssertion(rdfs:label "negative regulation of transport across blood-brain barrier") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (Leydig cell proliferation) - -AnnotationAssertion(Annotation( "PMID:29632025") "The multiplication or reproduction of Leydig cells, resulting in the expansion of a cell population. Leydig cells are interstitial cells located adjacent to the seminiferous tubules in the testis which produce testosterone.") -AnnotationAssertion( "rynl") -AnnotationAssertion( "2022-02-08T20:09:53Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0160024") -AnnotationAssertion(rdfs:label "Leydig cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (somatic sensory system development) - -AnnotationAssertion(Annotation( "PMID:25832476") Annotation( "PMID:31399790") "The process whose specific outcome is the progression of a somatic sensory system over time from its formation to the mature structure. Somatic sensory system is the sensory system for the sense of touch and pain.") -AnnotationAssertion( "rynl") -AnnotationAssertion( "2022-07-07T16:49:26Z") -AnnotationAssertion( "somatosensory system development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0160038") -AnnotationAssertion(rdfs:label "somatic sensory system development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (catecholamine secretion, neurotransmission) - -AnnotationAssertion(Annotation( "PMID:10191060") "The regulated release of catecholamine by a cell in which the catecholamine acts as a neurotransmitter.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/23804"^^xsd:anyURI) -AnnotationAssertion( "rynl") -AnnotationAssertion( "2022-08-17T00:36:44Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0160043") -AnnotationAssertion(rdfs:label "catecholamine secretion, neurotransmission") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (craniofacial suture closure) - -AnnotationAssertion(Annotation( "PMID:33842480") "The process of fusing together the edges of a craniofacial suture.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/23213"^^xsd:anyURI) -AnnotationAssertion( "rynl") -AnnotationAssertion( "2022-08-19T23:18:54Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0160048") -AnnotationAssertion(rdfs:label "craniofacial suture closure") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of dendrite development) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that activates or increases the frequency, rate or extent of dendrite development.") -AnnotationAssertion( "hjd") -AnnotationAssertion( "2012-01-09T10:41:31Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of dendrite development") -AnnotationAssertion( "GO:1900006") -AnnotationAssertion(rdfs:label "positive regulation of dendrite development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of cytokine production involved in inflammatory response) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that modulates the frequency, rate or extent of cytokine production involved in inflammatory response.") -AnnotationAssertion( "rph") -AnnotationAssertion( "2012-01-11T09:34:27Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of cytokine production involved in acute inflammatory response") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1900015") -AnnotationAssertion(rdfs:label "regulation of cytokine production involved in inflammatory response") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of cytokine production involved in inflammatory response) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that stops, prevents or reduces the frequency, rate or extent of cytokine production involved in inflammatory response.") -AnnotationAssertion( "rph") -AnnotationAssertion( "2012-01-11T09:34:31Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of cytokine production involved in acute inflammatory response") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of cytokine production involved in acute inflammatory response") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of cytokine production involved in inflammatory response") -AnnotationAssertion( "GO:1900016") -AnnotationAssertion(rdfs:label "negative regulation of cytokine production involved in inflammatory response") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of cytokine production involved in inflammatory response) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that activates or increases the frequency, rate or extent of cytokine production involved in inflammatory response.") -AnnotationAssertion( "rph") -AnnotationAssertion( "2012-01-11T09:34:35Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of cytokine production involved in acute inflammatory response") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of cytokine production involved in acute inflammatory response") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of cytokine production involved in inflammatory response") -AnnotationAssertion( "GO:1900017") -AnnotationAssertion(rdfs:label "positive regulation of cytokine production involved in inflammatory response") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of hemostasis) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that modulates the frequency, rate or extent of hemostasis.") -AnnotationAssertion( "jl") -AnnotationAssertion( "2012-01-19T03:23:38Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1900046") -AnnotationAssertion(rdfs:label "regulation of hemostasis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of hemostasis) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that stops, prevents or reduces the frequency, rate or extent of hemostasis.") -AnnotationAssertion( "jl") -AnnotationAssertion( "2012-01-19T03:23:42Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of hemostasis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of hemostasis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of hemostasis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of hemostasis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1900047") -AnnotationAssertion(rdfs:label "negative regulation of hemostasis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of hemostasis) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that activates or increases the frequency, rate or extent of hemostasis.") -AnnotationAssertion( "jl") -AnnotationAssertion( "2012-01-19T03:23:45Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of hemostasis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of hemostasis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of hemostasis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of hemostasis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1900048") -AnnotationAssertion(rdfs:label "positive regulation of hemostasis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of ceramide biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "PMID:15302821") "Any process that stops, prevents or reduces the frequency, rate or extent of a ceramide biosynthetic process.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2012-01-25T03:18:07Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of ceramide anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of ceramide biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of ceramide formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of ceramide synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of ceramide anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of ceramide biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of ceramide formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of ceramide synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of ceramide anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of ceramide biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of ceramide formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of ceramide synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of ceramide anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of ceramide biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of ceramide formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of ceramide synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of ceramide anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of ceramide biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of ceramide formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of ceramide synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of ceramide biosynthetic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of ceramide biosynthetic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of ceramide biosynthetic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of ceramide biosynthetic process") -AnnotationAssertion( "GO:1900060") -AnnotationAssertion(rdfs:label "negative regulation of ceramide biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of neuromuscular synaptic transmission) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:kmv") "Any process that modulates the frequency, rate or extent of neuromuscular synaptic transmission.") -AnnotationAssertion( "kmv") -AnnotationAssertion( "2012-01-26T10:14:10Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1900073") -AnnotationAssertion(rdfs:label "regulation of neuromuscular synaptic transmission") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of neuromuscular synaptic transmission) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:kmv") "Any process that stops, prevents or reduces the frequency, rate or extent of neuromuscular synaptic transmission.") -AnnotationAssertion( "kmv") -AnnotationAssertion( "2012-01-26T10:14:18Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of neuromuscular synaptic transmission") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of neuromuscular synaptic transmission") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of neuromuscular synaptic transmission") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of neuromuscular synaptic transmission") -AnnotationAssertion( "GO:1900074") -AnnotationAssertion(rdfs:label "negative regulation of neuromuscular synaptic transmission") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of neuromuscular synaptic transmission) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:kmv") "Any process that activates or increases the frequency, rate or extent of neuromuscular synaptic transmission.") -AnnotationAssertion( "kmv") -AnnotationAssertion( "2012-01-26T10:14:22Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of neuromuscular synaptic transmission") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of neuromuscular synaptic transmission") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of neuromuscular synaptic transmission") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of neuromuscular synaptic transmission") -AnnotationAssertion( "GO:1900075") -AnnotationAssertion(rdfs:label "positive regulation of neuromuscular synaptic transmission") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of cellular response to insulin stimulus) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:yaf") "Any process that modulates the frequency, rate or extent of cellular response to insulin stimulus.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2012-01-31T11:22:22Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1900076") -AnnotationAssertion(rdfs:label "regulation of cellular response to insulin stimulus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of cellular response to insulin stimulus) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:yaf") "Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to insulin stimulus.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2012-01-31T11:23:15Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of cellular response to insulin stimulus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of cellular response to insulin stimulus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of cellular response to insulin stimulus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of cellular response to insulin stimulus") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1900077") -AnnotationAssertion(rdfs:label "negative regulation of cellular response to insulin stimulus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of cellular response to insulin stimulus) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:yaf") "Any process that activates or increases the frequency, rate or extent of cellular response to insulin stimulus.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2012-01-31T11:24:30Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of cellular response to insulin stimulus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of cellular response to insulin stimulus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of cellular response to insulin stimulus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of cellular response to insulin stimulus") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1900078") -AnnotationAssertion(rdfs:label "positive regulation of cellular response to insulin stimulus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of plasma cell differentiation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that modulates the frequency, rate or extent of plasma cell differentiation.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2012-02-15T10:46:00Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of plasma cell development") -AnnotationAssertion( "GO:1900098") -AnnotationAssertion(rdfs:label "regulation of plasma cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of plasma cell differentiation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that stops, prevents or reduces the frequency, rate or extent of plasma cell differentiation.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2012-02-15T10:46:05Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of plasma cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of plasma cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of plasma cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of plasma cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of plasma cell development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of plasma cell development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of plasma cell development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of plasma cell development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of plasma cell development") -AnnotationAssertion( "GO:1900099") -AnnotationAssertion(rdfs:label "negative regulation of plasma cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of plasma cell differentiation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that activates or increases the frequency, rate or extent of plasma cell differentiation.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2012-02-15T10:46:08Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of plasma cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of plasma cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of plasma cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of plasma cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of plasma cell development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of plasma cell development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of plasma cell development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of plasma cell development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of plasma cell development") -AnnotationAssertion( "GO:1900100") -AnnotationAssertion(rdfs:label "positive regulation of plasma cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (extracellular regulation of signal transduction) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:signaling") "Any regulation of signal transduction that takes place in the extracellular region.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2012-02-22T10:21:48Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of signaling pathway in extracellular region") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of signalling pathway in extracellular region") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1900115") -AnnotationAssertion(rdfs:label "extracellular regulation of signal transduction") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (extracellular negative regulation of signal transduction) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:signaling") "Any negative regulation of signal transduction that takes place in extracellular region.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2012-02-22T10:27:56Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of signal transduction in extracellular region") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of signal transduction in extracellular region") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of signal transduction in extracellular region") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of signaling pathway in extracellular region") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of signalling pathway in extracellular region") -AnnotationAssertion(Annotation( "GOC:bf") "extracellular inhibition of signaling pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of signal transduction in extracellular region") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1900116") -AnnotationAssertion(rdfs:label "extracellular negative regulation of signal transduction") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of execution phase of apoptosis) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mtg_apoptosis") "Any process that modulates the frequency, rate or extent of execution phase of apoptosis.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2012-02-22T11:26:20Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1900117") -AnnotationAssertion(rdfs:label "regulation of execution phase of apoptosis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of execution phase of apoptosis) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mtg_apoptosis") "Any process that stops, prevents or reduces the frequency, rate or extent of execution phase of apoptosis.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2012-02-22T11:26:24Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of execution phase of apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of execution phase of apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of execution phase of apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of execution phase of apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1900118") -AnnotationAssertion(rdfs:label "negative regulation of execution phase of apoptosis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of execution phase of apoptosis) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mtg_apoptosis") "Any process that activates or increases the frequency, rate or extent of execution phase of apoptosis.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2012-02-22T11:26:27Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of execution phase of apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of execution phase of apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of execution phase of apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of execution phase of apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1900119") -AnnotationAssertion(rdfs:label "positive regulation of execution phase of apoptosis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (regulation of receptor binding) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:signaling") "Any process that modulates the frequency, rate or extent of a protein or other molecule binding to a receptor.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2012-02-22T11:40:53Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of receptor ligand") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1900120") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "regulation of receptor binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of receptor binding) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:signaling") "Any process that stops, prevents or reduces the frequency, rate or extent of a protein or other molecule binding to a receptor.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2012-02-22T11:40:57Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of receptor binding") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of receptor binding") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of receptor binding") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of receptor binding") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of receptor ligand") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of receptor-associated protein activity") -AnnotationAssertion( "GO:1900121") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "negative regulation of receptor binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of receptor binding) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:signaling") "Any process that activates or increases the frequency, rate or extent of a protein or other molecule binding to a receptor.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2012-02-22T11:41:00Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of receptor binding") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of receptor binding") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of receptor binding") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1900122") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "positive regulation of receptor binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of hyaluronan biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:yaf") "Any process that modulates the frequency, rate or extent of hyaluronan biosynthetic process.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2012-02-23T01:09:21Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of hyaluronan anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of hyaluronan biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of hyaluronan formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of hyaluronan synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1900125") -AnnotationAssertion(rdfs:label "regulation of hyaluronan biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (negative regulation of hyaluronan biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:yaf") "Any process that stops, prevents or reduces the frequency, rate or extent of hyaluronan biosynthetic process.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2012-02-23T01:09:29Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of hyaluronan anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of hyaluronan biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of hyaluronan biosynthetic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of hyaluronan formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of hyaluronan synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of hyaluronan anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of hyaluronan biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of hyaluronan biosynthetic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of hyaluronan formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of hyaluronan synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of hyaluronan anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of hyaluronan biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of hyaluronan biosynthetic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of hyaluronan formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of hyaluronan synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of hyaluronan anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of hyaluronan biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of hyaluronan formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of hyaluronan synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of hyaluronan anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of hyaluronan biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of hyaluronan formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of hyaluronan synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of hyaluronan biosynthetic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1900126") -AnnotationAssertion(rdfs:label "negative regulation of hyaluronan biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (positive regulation of hyaluronan biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:yaf") "Any process that activates or increases the frequency, rate or extent of hyaluronan biosynthetic process.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2012-02-23T01:09:33Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of hyaluronan anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of hyaluronan biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of hyaluronan formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of hyaluronan synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of hyaluronan anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of hyaluronan biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of hyaluronan formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of hyaluronan synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of hyaluronan anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of hyaluronan biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of hyaluronan biosynthetic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of hyaluronan formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of hyaluronan synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of hyaluronan anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of hyaluronan biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of hyaluronan biosynthetic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of hyaluronan formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of hyaluronan synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of hyaluronan anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of hyaluronan biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of hyaluronan biosynthetic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of hyaluronan formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of hyaluronan synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of hyaluronan biosynthetic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1900127") -AnnotationAssertion(rdfs:label "positive regulation of hyaluronan biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of lipid binding) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:pm") "Any process that modulates the frequency, rate or extent of lipid binding.") -AnnotationAssertion( "pm") -AnnotationAssertion( "2012-02-23T04:05:03Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1900130") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "regulation of lipid binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of lipid binding) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:pm") "Any process that stops, prevents or reduces the frequency, rate or extent of lipid binding.") -AnnotationAssertion( "pm") -AnnotationAssertion( "2012-02-23T04:05:07Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of lipid binding") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of lipid binding") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of lipid binding") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of lipid binding") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1900131") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "negative regulation of lipid binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of lipid binding) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:pm") "Any process that activates or increases the frequency, rate or extent of lipid binding.") -AnnotationAssertion( "pm") -AnnotationAssertion( "2012-02-23T04:05:11Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of lipid binding") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of lipid binding") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of lipid binding") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of lipid binding") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1900132") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "positive regulation of lipid binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of renin secretion into blood stream) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that modulates the frequency, rate or extent of renin secretion into blood stream.") -AnnotationAssertion( "rph") -AnnotationAssertion( "2012-02-27T10:32:01Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of renin release into blood stream") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1900133") -AnnotationAssertion(rdfs:label "regulation of renin secretion into blood stream") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (negative regulation of renin secretion into blood stream) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that stops, prevents or reduces the frequency, rate or extent of renin secretion into blood stream.") -AnnotationAssertion( "rph") -AnnotationAssertion( "2012-02-27T10:32:05Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of renin release into blood stream") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of renin secretion into blood stream") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of renin release into blood stream") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of renin secretion into blood stream") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of renin release into blood stream") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of renin secretion into blood stream") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of renin release into blood stream") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of renin release into blood stream") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of renin secretion into blood stream") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1900134") -AnnotationAssertion(rdfs:label "negative regulation of renin secretion into blood stream") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of renin secretion into blood stream) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that activates or increases the frequency, rate or extent of renin secretion into blood stream.") -AnnotationAssertion( "rph") -AnnotationAssertion( "2012-02-27T10:32:08Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of renin release into blood stream") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of renin release into blood stream") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of renin secretion into blood stream") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of renin release into blood stream") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of renin secretion into blood stream") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of renin release into blood stream") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of renin secretion into blood stream") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of renin release into blood stream") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of renin secretion into blood stream") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1900135") -AnnotationAssertion(rdfs:label "positive regulation of renin secretion into blood stream") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of oligodendrocyte apoptotic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:yaf") "Any process that modulates the frequency, rate or extent of oligodendrocyte apoptotic process.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2012-03-06T10:22:45Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of oligodendrocyte apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1900141") -AnnotationAssertion(rdfs:label "regulation of oligodendrocyte apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of oligodendrocyte apoptotic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:yaf") "Any process that stops, prevents or reduces the frequency, rate or extent of oligodendrocyte apoptotic process.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2012-03-06T10:22:50Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of oligodendrocyte apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of oligodendrocyte apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of oligodendrocyte apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of oligodendrocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of oligodendrocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of oligodendrocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of oligodendrocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of oligodendrocyte apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of oligodendrocyte apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1900142") -AnnotationAssertion(rdfs:label "negative regulation of oligodendrocyte apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of oligodendrocyte apoptotic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:yaf") "Any process that activates or increases the frequency, rate or extent of oligodendrocyte apoptotic process.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2012-03-06T10:22:54Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of oligodendrocyte apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of oligodendrocyte apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of oligodendrocyte apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of oligodendrocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of oligodendrocyte apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of oligodendrocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of oligodendrocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of oligodendrocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of oligodendrocyte apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1900143") -AnnotationAssertion(rdfs:label "positive regulation of oligodendrocyte apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of Schwann cell migration) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:sjw") "Any process that modulates the frequency, rate or extent of Schwann cell migration.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2012-03-06T04:14:50Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1900147") -AnnotationAssertion(rdfs:label "regulation of Schwann cell migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of Schwann cell migration) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:sjw") "Any process that stops, prevents or reduces the frequency, rate or extent of Schwann cell migration.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2012-03-06T04:14:55Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of Schwann cell migration") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of Schwann cell migration") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of Schwann cell migration") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of Schwann cell migration") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1900148") -AnnotationAssertion(rdfs:label "negative regulation of Schwann cell migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of Schwann cell migration) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:sjw") "Any process that activates or increases the frequency, rate or extent of Schwann cell migration.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2012-03-06T04:14:58Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of Schwann cell migration") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of Schwann cell migration") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of Schwann cell migration") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of Schwann cell migration") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1900149") -AnnotationAssertion(rdfs:label "positive regulation of Schwann cell migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of defense response to fungus) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:dhl") Annotation( "PMID:22242006") "Any process that modulates the frequency, rate or extent of defense response to fungus.") -AnnotationAssertion( "dhl") -AnnotationAssertion( "2012-03-06T10:00:16Z") -AnnotationAssertion( "GO:2000072") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of defence response to fungi") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of defence response to fungus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of defense response to fungi") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of defense response to fungi, incompatible interaction") -AnnotationAssertion( "regulation of defense response to fungus, incompatible interaction") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of resistance response to pathogenic fungi") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of resistance response to pathogenic fungus") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of response to pathogenic fungus (incompatible interaction)") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1900150") -AnnotationAssertion(rdfs:label "regulation of defense response to fungus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of bone trabecula formation) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") "Any process that modulates the frequency, rate or extent of bone trabecula formation.") -AnnotationAssertion( "vk") -AnnotationAssertion( "2012-03-07T01:47:03Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of bone trabeculation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of skeletal trabecula formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of skeletal trabeculation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of bone trabecula biogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of skeletal trabecula biogenesis") -AnnotationAssertion( "GO:1900154") -AnnotationAssertion(rdfs:label "regulation of bone trabecula formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of bone trabecula formation) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") "Any process that stops, prevents or reduces the frequency, rate or extent of bone trabecula formation.") -AnnotationAssertion( "vk") -AnnotationAssertion( "2012-03-07T01:47:07Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of bone trabecula formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of bone trabeculation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of skeletal trabecula formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of skeletal trabeculation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of bone trabecula formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of bone trabeculation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of skeletal trabecula formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of skeletal trabeculation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of bone trabecula formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of bone trabeculation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of skeletal trabecula formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of skeletal trabeculation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of bone trabeculation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of skeletal trabecula formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of skeletal trabeculation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of bone trabecula formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of bone trabeculation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of skeletal trabecula formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of skeletal trabeculation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of bone trabecula biogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of skeletal trabecula biogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of bone trabecula biogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of skeletal trabecula biogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of bone trabecula biogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of skeletal trabecula biogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of bone trabecula biogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of skeletal trabecula biogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of bone trabecula biogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of skeletal trabecula biogenesis") -AnnotationAssertion( "GO:1900155") -AnnotationAssertion(rdfs:label "negative regulation of bone trabecula formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of bone trabecula formation) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") "Any process that activates or increases the frequency, rate or extent of bone trabecula formation.") -AnnotationAssertion( "vk") -AnnotationAssertion( "2012-03-07T01:47:10Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of bone trabeculation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of skeletal trabecula formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of skeletal trabeculation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of bone trabecula formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of bone trabeculation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of skeletal trabecula formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of skeletal trabeculation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of bone trabecula formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of bone trabeculation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of skeletal trabecula formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of skeletal trabeculation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of bone trabecula formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of bone trabeculation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of skeletal trabecula formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of skeletal trabeculation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of bone trabecula formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of bone trabeculation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of skeletal trabecula formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of skeletal trabeculation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of bone trabecula biogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of skeletal trabecula biogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of bone trabecula biogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of skeletal trabecula biogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of bone trabecula biogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of skeletal trabecula biogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of bone trabecula biogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of skeletal trabecula biogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of bone trabecula biogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of skeletal trabecula biogenesis") -AnnotationAssertion( "GO:1900156") -AnnotationAssertion(rdfs:label "positive regulation of bone trabecula formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of bone mineralization involved in bone maturation) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") "Any process that modulates the frequency, rate or extent of bone mineralization involved in bone maturation.") -AnnotationAssertion( "vk") -AnnotationAssertion( "2012-03-07T08:55:07Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1900157") -AnnotationAssertion(rdfs:label "regulation of bone mineralization involved in bone maturation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of bone mineralization involved in bone maturation) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") "Any process that stops, prevents or reduces the frequency, rate or extent of bone mineralization involved in bone maturation.") -AnnotationAssertion( "vk") -AnnotationAssertion( "2012-03-07T08:55:12Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of bone mineralization involved in bone maturation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of bone mineralization involved in bone maturation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of bone mineralization involved in bone maturation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of bone mineralization involved in bone maturation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1900158") -AnnotationAssertion(rdfs:label "negative regulation of bone mineralization involved in bone maturation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of bone mineralization involved in bone maturation) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") "Any process that activates or increases the frequency, rate or extent of bone mineralization involved in bone maturation.") -AnnotationAssertion( "vk") -AnnotationAssertion( "2012-03-07T08:55:16Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of bone mineralization involved in bone maturation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of bone mineralization involved in bone maturation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of bone mineralization involved in bone maturation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of bone mineralization involved in bone maturation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1900159") -AnnotationAssertion(rdfs:label "positive regulation of bone mineralization involved in bone maturation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of glucocorticoid mediated signaling pathway) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that modulates the frequency, rate or extent of glucocorticoid mediated signaling pathway.") -AnnotationAssertion( "hjd") -AnnotationAssertion( "2012-03-08T08:33:16Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of glucocorticoid mediated signalling") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1900169") -AnnotationAssertion(rdfs:label "regulation of glucocorticoid mediated signaling pathway") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of glucocorticoid mediated signaling pathway) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that stops, prevents or reduces the frequency, rate or extent of glucocorticoid mediated signaling pathway.") -AnnotationAssertion( "hjd") -AnnotationAssertion( "2012-03-08T08:33:20Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of glucocorticoid mediated signaling pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of glucocorticoid mediated signalling") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of glucocorticoid mediated signaling pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of glucocorticoid mediated signalling") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of glucocorticoid mediated signaling pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of glucocorticoid mediated signalling") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of glucocorticoid mediated signalling") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of glucocorticoid mediated signaling pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of glucocorticoid mediated signalling") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1900170") -AnnotationAssertion(rdfs:label "negative regulation of glucocorticoid mediated signaling pathway") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of glucocorticoid mediated signaling pathway) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that activates or increases the frequency, rate or extent of glucocorticoid mediated signaling pathway.") -AnnotationAssertion( "hjd") -AnnotationAssertion( "2012-03-08T08:33:23Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of glucocorticoid mediated signalling") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of glucocorticoid mediated signaling pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of glucocorticoid mediated signalling") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of glucocorticoid mediated signaling pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of glucocorticoid mediated signalling") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of glucocorticoid mediated signaling pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of glucocorticoid mediated signalling") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of glucocorticoid mediated signaling pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of glucocorticoid mediated signalling") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1900171") -AnnotationAssertion(rdfs:label "positive regulation of glucocorticoid mediated signaling pathway") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of protein localization to nucleus) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that modulates the frequency, rate or extent of protein localization to nucleus.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2012-03-12T01:23:44Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of protein localisation to nucleus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of protein localization in cell nucleus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of protein localization in nucleus") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1900180") -AnnotationAssertion(rdfs:label "regulation of protein localization to nucleus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of protein localization to nucleus) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to nucleus.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2012-03-12T01:23:48Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of protein localisation to nucleus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of protein localization in cell nucleus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of protein localization in nucleus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of protein localization to nucleus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of protein localisation to nucleus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of protein localization in cell nucleus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of protein localization in nucleus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of protein localization to nucleus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of protein localisation to nucleus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of protein localization in cell nucleus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of protein localization in nucleus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of protein localization to nucleus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of protein localisation to nucleus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of protein localization in cell nucleus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of protein localization in nucleus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of protein localisation to nucleus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of protein localization in cell nucleus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of protein localization in nucleus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of protein localization to nucleus") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1900181") -AnnotationAssertion(rdfs:label "negative regulation of protein localization to nucleus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of protein localization to nucleus) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that activates or increases the frequency, rate or extent of protein localization to nucleus.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2012-03-12T01:23:52Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of protein localization in nucleus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of protein localisation to nucleus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of protein localization in cell nucleus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of protein localization in nucleus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of protein localisation to nucleus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of protein localization in cell nucleus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of protein localization in nucleus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of protein localization to nucleus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of protein localisation to nucleus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of protein localization in cell nucleus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of protein localization in nucleus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of protein localization to nucleus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of protein localisation to nucleus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of protein localization in cell nucleus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of protein localization in nucleus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of protein localization to nucleus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of protein localisation to nucleus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of protein localization in cell nucleus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of protein localization to nucleus") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1900182") -AnnotationAssertion(rdfs:label "positive regulation of protein localization to nucleus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of oocyte maturation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:kmv") "Any process that modulates the frequency, rate or extent of oocyte maturation.") -AnnotationAssertion( "kmv") -AnnotationAssertion( "2012-03-19T09:41:18Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1900193") -AnnotationAssertion(rdfs:label "regulation of oocyte maturation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of oocyte maturation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:kmv") "Any process that stops, prevents or reduces the frequency, rate or extent of oocyte maturation.") -AnnotationAssertion( "kmv") -AnnotationAssertion( "2012-03-19T09:41:27Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of oocyte maturation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of oocyte maturation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of oocyte maturation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of oocyte maturation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1900194") -AnnotationAssertion(rdfs:label "negative regulation of oocyte maturation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of oocyte maturation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:kmv") "Any process that activates or increases the frequency, rate or extent of oocyte maturation.") -AnnotationAssertion( "kmv") -AnnotationAssertion( "2012-03-19T09:41:35Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of oocyte maturation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of oocyte maturation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of oocyte maturation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of oocyte maturation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1900195") -AnnotationAssertion(rdfs:label "positive regulation of oocyte maturation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (mesenchymal cell apoptotic process involved in metanephros development) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:mtg_kidney_jan10") Annotation( "GOC:yaf") Annotation( "PMID:17314325") "Any mesenchymal cell apoptotic process that is involved in metanephros development.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2012-03-21T11:58:05Z") -AnnotationAssertion( "mesenchymal cell apoptosis involved in metanephros development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1900200") -AnnotationAssertion(rdfs:label "mesenchymal cell apoptotic process involved in metanephros development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (apoptotic process involved in metanephric collecting duct development) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mtg_kidney_jan10") Annotation( "GOC:yaf") Annotation( "PMID:17314325") "Any apoptotic process that is involved in metanephric collecting duct development.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2012-03-21T01:21:32Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "apoptotic cell death of metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "apoptotic process of metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "apoptotic programmed cell death of metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "programmed cell death by apoptosis of metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "apoptosis of metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "apoptotic program of metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "type I programmed cell death of metanephric collecting duct development") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "signaling (initiator) caspase activity of metanephric collecting duct development") -AnnotationAssertion( "GO:1900204") -AnnotationAssertion(rdfs:label "apoptotic process involved in metanephric collecting duct development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (apoptotic process involved in metanephric nephron tubule development) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mtg_kidney_jan10") Annotation( "GOC:yaf") Annotation( "PMID:17314325") "Any apoptotic process that is involved in metanephric nephron tubule development.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2012-03-21T01:21:45Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "apoptotic cell death of metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "apoptotic process of metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "apoptotic programmed cell death of metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "programmed cell death by apoptosis of metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "apoptosis of metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "apoptotic program of metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "type I programmed cell death of metanephric nephron tubule development") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "signaling (initiator) caspase activity of metanephric nephron tubule development") -AnnotationAssertion( "GO:1900205") -AnnotationAssertion(rdfs:label "apoptotic process involved in metanephric nephron tubule development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of pronephric nephron tubule development) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that modulates the frequency, rate or extent of pronephric nephron tubule development.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2012-03-22T09:23:13Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1900206") -AnnotationAssertion(rdfs:label "regulation of pronephric nephron tubule development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of pronephric nephron tubule development) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:bf") Annotation( "PMID:9758706") "Any process that stops, prevents or reduces the frequency, rate or extent of pronephric nephron tubule development.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2012-03-22T09:23:23Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of pronephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of pronephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of pronephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of pronephric nephron tubule development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1900207") -AnnotationAssertion(rdfs:label "negative regulation of pronephric nephron tubule development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of mesenchymal cell apoptotic process involved in metanephros development) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:mtg_kidney_jan10") Annotation( "GOC:yaf") Annotation( "PMID:17314325") "Any process that modulates the frequency, rate or extent of mesenchymal cell apoptotic process involved in metanephros development.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2012-03-22T10:52:50Z") -AnnotationAssertion( "regulation of mesenchymal cell apoptosis involved in metanephros development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1900211") -AnnotationAssertion(rdfs:label "regulation of mesenchymal cell apoptotic process involved in metanephros development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of mesenchymal cell apoptotic process involved in metanephros development) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:mtg_kidney_jan10") Annotation( "GOC:yaf") Annotation( "PMID:17314325") "Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal cell apoptotic process involved in metanephros development.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2012-03-22T10:53:00Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of mesenchymal cell apoptosis involved in metanephros development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of mesenchymal cell apoptosis involved in metanephros development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of mesenchymal cell apoptosis involved in metanephros development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of mesenchymal cell apoptosis involved in metanephros development") -AnnotationAssertion( "negative regulation of mesenchymal cell apoptosis involved in metanephros development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1900212") -AnnotationAssertion(rdfs:label "negative regulation of mesenchymal cell apoptotic process involved in metanephros development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of mesenchymal cell apoptotic process involved in metanephros development) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:mtg_kidney_jan10") Annotation( "GOC:yaf") Annotation( "PMID:17314325") "Any process that activates or increases the frequency, rate or extent of mesenchymal cell apoptotic process involved in metanephros development.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2012-03-22T10:53:09Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of mesenchymal cell apoptosis involved in metanephros development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of mesenchymal cell apoptosis involved in metanephros development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of mesenchymal cell apoptosis involved in metanephros development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of mesenchymal cell apoptosis involved in metanephros development") -AnnotationAssertion( "positive regulation of mesenchymal cell apoptosis involved in metanephros development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1900213") -AnnotationAssertion(rdfs:label "positive regulation of mesenchymal cell apoptotic process involved in metanephros development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of apoptotic process involved in metanephric collecting duct development) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mtg_kidney_jan10") Annotation( "GOC:yaf") Annotation( "PMID:17314325") "Any process that modulates the frequency, rate or extent of apoptotic process involved in metanephric collecting duct development.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2012-03-22T10:53:21Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of apoptotic cell death of metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of apoptotic process of metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of apoptotic programmed cell death of metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of programmed cell death by apoptosis of metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of apoptosis of metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of apoptotic program of metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of type I programmed cell death of metanephric collecting duct development") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of signaling (initiator) caspase activity of metanephric collecting duct development") -AnnotationAssertion( "GO:1900214") -AnnotationAssertion(rdfs:label "regulation of apoptotic process involved in metanephric collecting duct development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of apoptotic process involved in metanephric collecting duct development) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mtg_kidney_jan10") Annotation( "GOC:yaf") Annotation( "PMID:17314325") "Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in metanephric collecting duct development.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2012-03-22T10:53:31Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of apoptotic cell death of metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of apoptotic process involved in metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of apoptotic process of metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of apoptotic programmed cell death of metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of programmed cell death by apoptosis of metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of apoptotic cell death of metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of apoptotic process involved in metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of apoptotic process of metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of apoptotic programmed cell death of metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of programmed cell death by apoptosis of metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of apoptotic cell death of metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of apoptotic process involved in metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of apoptotic process of metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of apoptotic programmed cell death of metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of programmed cell death by apoptosis of metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of apoptotic cell death of metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of apoptotic process of metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of apoptotic programmed cell death of metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of programmed cell death by apoptosis of metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of apoptotic cell death of metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of apoptotic process of metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of apoptotic programmed cell death of metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of programmed cell death by apoptosis of metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of apoptosis of metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of apoptotic program of metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of type I programmed cell death of metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of apoptosis of metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of apoptotic program of metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of type I programmed cell death of metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of apoptosis of metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of apoptotic program of metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of type I programmed cell death of metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of apoptosis of metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of apoptotic process involved in metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of apoptotic program of metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of type I programmed cell death of metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of apoptosis of metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of apoptotic program of metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of type I programmed cell death of metanephric collecting duct development") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of signaling (initiator) caspase activity of metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of signaling (initiator) caspase activity of metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of signaling (initiator) caspase activity of metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of signaling (initiator) caspase activity of metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of signaling (initiator) caspase activity of metanephric collecting duct development") -AnnotationAssertion( "GO:1900215") -AnnotationAssertion(rdfs:label "negative regulation of apoptotic process involved in metanephric collecting duct development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of apoptotic process involved in metanephric collecting duct development) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mtg_kidney_jan10") Annotation( "GOC:yaf") Annotation( "PMID:17314325") "Any process that activates or increases the frequency, rate or extent of apoptotic process involved in metanephric collecting duct development.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2012-03-22T10:53:39Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of apoptotic cell death of metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of apoptotic process of metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of apoptotic programmed cell death of metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of programmed cell death by apoptosis of metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of apoptotic cell death of metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of apoptotic process of metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of apoptotic programmed cell death of metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of programmed cell death by apoptosis of metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of apoptotic cell death of metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of apoptotic process involved in metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of apoptotic process of metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of apoptotic programmed cell death of metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of programmed cell death by apoptosis of metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of apoptotic cell death of metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of apoptotic process involved in metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of apoptotic process of metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of apoptotic programmed cell death of metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of programmed cell death by apoptosis of metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of apoptotic cell death of metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of apoptotic process involved in metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of apoptotic process of metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of apoptotic programmed cell death of metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of programmed cell death by apoptosis of metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of apoptosis of metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of apoptotic process involved in metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of apoptotic program of metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of type I programmed cell death of metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of apoptosis of metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of apoptotic program of metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of type I programmed cell death of metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of apoptosis of metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of apoptotic program of metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of type I programmed cell death of metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of apoptosis of metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of apoptotic program of metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of type I programmed cell death of metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of apoptosis of metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of apoptotic program of metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of type I programmed cell death of metanephric collecting duct development") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of signaling (initiator) caspase activity of metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of signaling (initiator) caspase activity of metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of signaling (initiator) caspase activity of metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of signaling (initiator) caspase activity of metanephric collecting duct development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of signaling (initiator) caspase activity of metanephric collecting duct development") -AnnotationAssertion( "GO:1900216") -AnnotationAssertion(rdfs:label "positive regulation of apoptotic process involved in metanephric collecting duct development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of apoptotic process involved in metanephric nephron tubule development) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mtg_kidney_jan10") Annotation( "GOC:yaf") Annotation( "PMID:17314325") "Any process that modulates the frequency, rate or extent of apoptotic process involved in metanephric nephron tubule development.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2012-03-22T10:53:51Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of apoptotic cell death of metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of apoptotic process of metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of apoptotic programmed cell death of metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of programmed cell death by apoptosis of metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of apoptosis of metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of apoptotic program of metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of type I programmed cell death of metanephric nephron tubule development") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of signaling (initiator) caspase activity of metanephric nephron tubule development") -AnnotationAssertion( "GO:1900217") -AnnotationAssertion(rdfs:label "regulation of apoptotic process involved in metanephric nephron tubule development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of apoptotic process involved in metanephric nephron tubule development) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mtg_kidney_jan10") Annotation( "GOC:yaf") Annotation( "PMID:17314325") "Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in metanephric nephron tubule development.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2012-03-22T10:54:01Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of apoptotic cell death of metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of apoptotic process involved in metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of apoptotic process of metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of apoptotic programmed cell death of metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of programmed cell death by apoptosis of metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of apoptotic cell death of metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of apoptotic process involved in metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of apoptotic process of metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of apoptotic programmed cell death of metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of programmed cell death by apoptosis of metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of apoptotic cell death of metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of apoptotic process involved in metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of apoptotic process of metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of apoptotic programmed cell death of metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of programmed cell death by apoptosis of metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of apoptotic cell death of metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of apoptotic process of metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of apoptotic programmed cell death of metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of programmed cell death by apoptosis of metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of apoptotic cell death of metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of apoptotic process of metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of apoptotic programmed cell death of metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of programmed cell death by apoptosis of metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of apoptosis of metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of apoptotic program of metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of type I programmed cell death of metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of apoptosis of metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of apoptotic program of metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of type I programmed cell death of metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of apoptosis of metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of apoptotic program of metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of type I programmed cell death of metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of apoptosis of metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of apoptotic process involved in metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of apoptotic program of metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of type I programmed cell death of metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of apoptosis of metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of apoptotic program of metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of type I programmed cell death of metanephric nephron tubule development") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of signaling (initiator) caspase activity of metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of signaling (initiator) caspase activity of metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of signaling (initiator) caspase activity of metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of signaling (initiator) caspase activity of metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of signaling (initiator) caspase activity of metanephric nephron tubule development") -AnnotationAssertion( "GO:1900218") -AnnotationAssertion(rdfs:label "negative regulation of apoptotic process involved in metanephric nephron tubule development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of apoptotic process involved in metanephric nephron tubule development) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mtg_kidney_jan10") Annotation( "GOC:yaf") Annotation( "PMID:17314325") "Any process that activates or increases the frequency, rate or extent of apoptotic process involved in metanephric nephron tubule development.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2012-03-22T10:54:09Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of apoptotic cell death of metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of apoptotic process of metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of apoptotic programmed cell death of metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of programmed cell death by apoptosis of metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of apoptotic cell death of metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of apoptotic process of metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of apoptotic programmed cell death of metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of programmed cell death by apoptosis of metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of apoptotic cell death of metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of apoptotic process involved in metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of apoptotic process of metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of apoptotic programmed cell death of metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of programmed cell death by apoptosis of metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of apoptotic cell death of metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of apoptotic process involved in metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of apoptotic process of metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of apoptotic programmed cell death of metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of programmed cell death by apoptosis of metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of apoptotic cell death of metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of apoptotic process involved in metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of apoptotic process of metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of apoptotic programmed cell death of metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of programmed cell death by apoptosis of metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of apoptosis of metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of apoptotic process involved in metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of apoptotic program of metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of type I programmed cell death of metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of apoptosis of metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of apoptotic program of metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of type I programmed cell death of metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of apoptosis of metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of apoptotic program of metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of type I programmed cell death of metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of apoptosis of metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of apoptotic program of metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of type I programmed cell death of metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of apoptosis of metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of apoptotic program of metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of type I programmed cell death of metanephric nephron tubule development") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of signaling (initiator) caspase activity of metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of signaling (initiator) caspase activity of metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of signaling (initiator) caspase activity of metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of signaling (initiator) caspase activity of metanephric nephron tubule development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of signaling (initiator) caspase activity of metanephric nephron tubule development") -AnnotationAssertion( "GO:1900219") -AnnotationAssertion(rdfs:label "positive regulation of apoptotic process involved in metanephric nephron tubule development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of cytoplasmic translational elongation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that modulates the frequency, rate or extent of cytoplasmic translational elongation.") -AnnotationAssertion( "vw") -AnnotationAssertion( "2012-04-03T05:07:02Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1900247") -AnnotationAssertion(rdfs:label "regulation of cytoplasmic translational elongation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of cytoplasmic translational elongation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic translational elongation.") -AnnotationAssertion( "vw") -AnnotationAssertion( "2012-04-03T05:07:14Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of cytoplasmic translational elongation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of cytoplasmic translational elongation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of cytoplasmic translational elongation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of cytoplasmic translational elongation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1900248") -AnnotationAssertion(rdfs:label "negative regulation of cytoplasmic translational elongation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of cytoplasmic translational elongation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that activates or increases the frequency, rate or extent of cytoplasmic translational elongation.") -AnnotationAssertion( "vw") -AnnotationAssertion( "2012-04-03T05:07:24Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of cytoplasmic translational elongation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of cytoplasmic translational elongation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of cytoplasmic translational elongation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of cytoplasmic translational elongation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1900249") -AnnotationAssertion(rdfs:label "positive regulation of cytoplasmic translational elongation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of defense response to insect) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "PMID:22474183") "Any process that stops, prevents or reduces the frequency, rate or extent of defense response to insect.") -AnnotationAssertion( "dhl") -AnnotationAssertion( "2012-04-12T04:44:00Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of defense response to insect") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of physiological defense response to insect") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of defense response to insect") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of physiological defense response to insect") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of defense response to insect") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of physiological defense response to insect") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of physiological defense response to insect") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of defense response to insect") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of physiological defense response to insect") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "susceptibility to insect") -AnnotationAssertion( "GO:1900366") -AnnotationAssertion(rdfs:label "negative regulation of defense response to insect") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of defense response to insect) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "PMID:22474183") "Any process that activates or increases the frequency, rate or extent of defense response to insect.") -AnnotationAssertion( "dhl") -AnnotationAssertion( "2012-04-12T04:44:10Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of physiological defense response to insect") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of defense response to insect") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of physiological defense response to insect") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of defense response to insect") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of physiological defense response to insect") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of defense response to insect") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of physiological defense response to insect") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of defense response to insect") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of physiological defense response to insect") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1900367") -AnnotationAssertion(rdfs:label "positive regulation of defense response to insect") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of purine nucleotide biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of purine nucleotide biosynthetic processes.") -AnnotationAssertion( "krc") -AnnotationAssertion( "2012-04-17T12:32:07Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of purine nucleotide anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of purine nucleotide biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of purine nucleotide formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of purine nucleotide synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1900371") -AnnotationAssertion(rdfs:label "regulation of purine nucleotide biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of purine nucleotide biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:go_curators") "Any process that stops, prevents or reduces the frequency, rate or extent of purine nucleotide biosynthetic processes.") -AnnotationAssertion( "krc") -AnnotationAssertion( "2012-04-17T12:32:27Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of purine nucleotide anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of purine nucleotide biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of purine nucleotide biosynthetic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of purine nucleotide formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of purine nucleotide synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of purine nucleotide anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of purine nucleotide biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of purine nucleotide biosynthetic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of purine nucleotide formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of purine nucleotide synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of purine nucleotide anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of purine nucleotide biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of purine nucleotide biosynthetic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of purine nucleotide formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of purine nucleotide synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of purine nucleotide anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of purine nucleotide biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of purine nucleotide formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of purine nucleotide synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of purine nucleotide anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of purine nucleotide biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of purine nucleotide formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of purine nucleotide synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of purine nucleotide biosynthetic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1900372") -AnnotationAssertion(rdfs:label "negative regulation of purine nucleotide biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of purine nucleotide biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of purine nucleotide biosynthetic processes.") -AnnotationAssertion( "krc") -AnnotationAssertion( "2012-04-17T12:32:37Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of purine nucleotide anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of purine nucleotide biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of purine nucleotide formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of purine nucleotide synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of purine nucleotide anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of purine nucleotide biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of purine nucleotide formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of purine nucleotide synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of purine nucleotide anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of purine nucleotide biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of purine nucleotide biosynthetic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of purine nucleotide formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of purine nucleotide synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of purine nucleotide anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of purine nucleotide biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of purine nucleotide biosynthetic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of purine nucleotide formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of purine nucleotide synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of purine nucleotide anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of purine nucleotide biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of purine nucleotide biosynthetic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of purine nucleotide formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of purine nucleotide synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of purine nucleotide biosynthetic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1900373") -AnnotationAssertion(rdfs:label "positive regulation of purine nucleotide biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of secondary metabolite biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:di") "Any process that modulates the frequency, rate or extent of secondary metabolite biosynthetic process.") -AnnotationAssertion( "di") -AnnotationAssertion( "2012-04-17T01:55:23Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of secondary metabolite biosynthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1900376") -AnnotationAssertion(rdfs:label "regulation of secondary metabolite biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of secondary metabolite biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:di") "Any process that stops, prevents or reduces the frequency, rate or extent of secondary metabolite biosynthetic process.") -AnnotationAssertion( "di") -AnnotationAssertion( "2012-04-17T01:55:32Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of secondary metabolite biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of secondary metabolite biosynthetic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of secondary metabolite biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of secondary metabolite biosynthetic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of secondary metabolite biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of secondary metabolite biosynthetic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of secondary metabolite biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of secondary metabolite biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of secondary metabolite biosynthetic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1900377") -AnnotationAssertion(rdfs:label "negative regulation of secondary metabolite biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of secondary metabolite biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:di") "Any process that activates or increases the frequency, rate or extent of secondary metabolite biosynthetic process.") -AnnotationAssertion( "di") -AnnotationAssertion( "2012-04-17T01:55:41Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of secondary metabolite biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of secondary metabolite biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of secondary metabolite biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of secondary metabolite biosynthetic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of secondary metabolite biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of secondary metabolite biosynthetic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of secondary metabolite biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of secondary metabolite biosynthetic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of secondary metabolite biosynthetic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1900378") -AnnotationAssertion(rdfs:label "positive regulation of secondary metabolite biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of cellular alcohol catabolic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that modulates the frequency, rate or extent of cellular alcohol catabolic process.") -AnnotationAssertion( "krc") -AnnotationAssertion( "2012-04-20T10:21:18Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1900419") -AnnotationAssertion(rdfs:label "regulation of cellular alcohol catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of cellular alcohol catabolic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that stops, prevents or reduces the frequency, rate or extent of cellular alcohol catabolic process.") -AnnotationAssertion( "krc") -AnnotationAssertion( "2012-04-20T10:21:28Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of cellular alcohol catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of cellular alcohol catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of cellular alcohol catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of cellular alcohol catabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1900420") -AnnotationAssertion(rdfs:label "negative regulation of cellular alcohol catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of cellular alcohol catabolic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that activates or increases the frequency, rate or extent of cellular alcohol catabolic process.") -AnnotationAssertion( "krc") -AnnotationAssertion( "2012-04-20T10:21:46Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of cellular alcohol catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of cellular alcohol catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of cellular alcohol catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of cellular alcohol catabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1900421") -AnnotationAssertion(rdfs:label "positive regulation of cellular alcohol catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of defense response to bacterium) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "PMID:22346749") "Any process that modulates the frequency, rate or extent of defense response to bacterium.") -AnnotationAssertion( "dhl") -AnnotationAssertion( "2012-04-24T10:12:43Z") -AnnotationAssertion( "GO:1902477") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of defence response to bacteria") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of defence response to bacterium") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of defense response to bacteria") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of defence response to bacterium, incompatible interaction") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of defence response to pathogenic bacteria, incompatible interaction") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of defence response to pathogenic bacterium, incompatible interaction") -AnnotationAssertion( "regulation of defense response to bacterium, incompatible interaction") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of resistance response to pathogenic bacteria") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of resistance response to pathogenic bacterium") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of antibacterial peptide activity") -AnnotationAssertion( "GO:1900424") -AnnotationAssertion(rdfs:label "regulation of defense response to bacterium") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of defense response to bacterium) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "PMID:22346749") "Any process that stops, prevents or reduces the frequency, rate or extent of defense response to bacterium.") -AnnotationAssertion( "dhl") -AnnotationAssertion( "2012-04-24T10:12:54Z") -AnnotationAssertion( "GO:1902478") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of defence response to bacteria") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of defence response to bacterium") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of defense response to bacteria") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of defense response to bacterium") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of defence response to bacteria") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of defence response to bacterium") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of defense response to bacteria") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of defense response to bacterium") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of defence response to bacteria") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of defence response to bacterium") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of defense response to bacteria") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of defense response to bacterium") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of defence response to bacteria") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of defence response to bacterium") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of defense response to bacteria") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of defence response to bacteria") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of defence response to bacterium") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of defense response to bacteria") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of defence response to pathogenic bacteria, incompatible interaction") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of defence response to pathogenic bacterium, incompatible interaction") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of defense response to bacterium") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of defense response to bacterium, incompatible interaction") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of resistance response to pathogenic bacteria") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of resistance response to pathogenic bacterium") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of response to pathogenic bacteria (incompatible interaction)") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of response to pathogenic bacterium (incompatible interaction)") -AnnotationAssertion( "negative regulation of defense response to bacterium, incompatible interaction") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of antibacterial peptide activity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of antibacterial peptide activity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of antibacterial peptide activity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of antibacterial peptide activity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of antibacterial peptide activity") -AnnotationAssertion( "GO:1900425") -AnnotationAssertion(rdfs:label "negative regulation of defense response to bacterium") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of defense response to bacterium) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "PMID:22346749") "Any process that activates or increases the frequency, rate or extent of defense response to bacterium.") -AnnotationAssertion( "dhl") -AnnotationAssertion( "2012-04-24T10:13:13Z") -AnnotationAssertion( "GO:1902479") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of defence response to bacteria") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of defence response to bacterium") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of defense response to bacteria") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of defence response to bacteria") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of defence response to bacterium") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of defense response to bacteria") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of defence response to bacteria") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of defence response to bacterium") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of defense response to bacteria") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of defense response to bacterium") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of defence response to bacteria") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of defence response to bacterium") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of defense response to bacteria") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of defense response to bacterium") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of defence response to bacteria") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of defence response to bacterium") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of defense response to bacteria") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of defense response to bacterium") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of defense response to bacterium") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of resistance response to pathogenic bacteria") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of resistance response to pathogenic bacterium") -AnnotationAssertion( "positive regulation of defense response to bacterium, incompatible interaction") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of antibacterial peptide activity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of antibacterial peptide activity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of antibacterial peptide activity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of antibacterial peptide activity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of antibacterial peptide activity") -AnnotationAssertion( "GO:1900426") -AnnotationAssertion(rdfs:label "positive regulation of defense response to bacterium") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of glutamate receptor signaling pathway) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") "Any process that modulates the frequency, rate or extent of glutamate receptor signaling pathway.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2012-04-27T03:45:43Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of glutamate signaling pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of glutamate signalling pathway") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1900449") -AnnotationAssertion(rdfs:label "regulation of glutamate receptor signaling pathway") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of glutamate receptor signaling pathway) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") "Any process that stops, prevents or reduces the frequency, rate or extent of glutamate receptor signaling pathway.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2012-04-27T03:45:53Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of glutamate receptor signaling pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of glutamate signaling pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of glutamate signalling pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of glutamate receptor signaling pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of glutamate signaling pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of glutamate signalling pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of glutamate receptor signaling pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of glutamate signaling pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of glutamate signalling pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of glutamate signaling pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of glutamate signalling pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of glutamate signaling pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of glutamate signalling pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of glutamate receptor signaling pathway") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1900450") -AnnotationAssertion(rdfs:label "negative regulation of glutamate receptor signaling pathway") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of glutamate receptor signaling pathway) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") "Any process that activates or increases the frequency, rate or extent of glutamate receptor signaling pathway.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2012-04-27T03:46:03Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of glutamate signaling pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of glutamate signalling pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of glutamate signaling pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of glutamate signalling pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of glutamate receptor signaling pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of glutamate signaling pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of glutamate signalling pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of glutamate receptor signaling pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of glutamate signaling pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of glutamate signalling pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of glutamate receptor signaling pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of glutamate signaling pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of glutamate signalling pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of glutamate receptor signaling pathway") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1900451") -AnnotationAssertion(rdfs:label "positive regulation of glutamate receptor signaling pathway") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of purine nucleotide metabolic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that modulates the frequency, rate or extent of purine nucleotide metabolic process.") -AnnotationAssertion( "krc") -AnnotationAssertion( "2012-05-11T05:43:15Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of purine nucleotide metabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of purine metabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of purine metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1900542") -AnnotationAssertion(rdfs:label "regulation of purine nucleotide metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of purine nucleotide metabolic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that stops, prevents or reduces the frequency, rate or extent of purine nucleotide metabolic process.") -AnnotationAssertion( "krc") -AnnotationAssertion( "2012-05-11T05:44:21Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of purine nucleotide metabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of purine nucleotide metabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of purine nucleotide metabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of purine nucleotide metabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of purine nucleotide metabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of purine nucleotide metabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of purine nucleotide metabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of purine metabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of purine metabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of purine metabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of purine metabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of purine metabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of purine metabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of purine metabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of purine metabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of purine nucleotide metabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of purine nucleotide metabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of purine metabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of purine metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1900543") -AnnotationAssertion(rdfs:label "negative regulation of purine nucleotide metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of purine nucleotide metabolic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that activates or increases the frequency, rate or extent of purine nucleotide metabolic process.") -AnnotationAssertion( "krc") -AnnotationAssertion( "2012-05-11T05:44:43Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of purine nucleotide metabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of purine nucleotide metabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of purine nucleotide metabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of purine nucleotide metabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of purine nucleotide metabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of purine nucleotide metabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of purine nucleotide metabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of purine metabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of purine metabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of purine nucleotide metabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of purine nucleotide metabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of purine metabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of purine metabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of purine metabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of purine metabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of purine metabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of purine metabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of purine metabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of purine metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1900544") -AnnotationAssertion(rdfs:label "positive regulation of purine nucleotide metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (acetate ester metabolic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "The chemical reactions and pathways involving an acetate ester, any carboxylic ester where the carboxylic acid component is acetic acid.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2012-05-16T12:29:51Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "acetate ester metabolism") -AnnotationAssertion(Annotation( "CHEBI:47622") "acetyl ester metabolic process") -AnnotationAssertion(Annotation( "CHEBI:47622") "acetyl ester metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1900619") -AnnotationAssertion(rdfs:label "acetate ester metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (acetate ester biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "PMID:15042596") "The chemical reactions and pathways resulting in the formation of an acetate esteran acetate ester, any carboxylic ester where the carboxylic acid component is acetic acid.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2012-05-16T12:30:12Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "acetate ester anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "acetate ester biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "acetate ester formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "acetate ester synthesis") -AnnotationAssertion(Annotation( "CHEBI:47622") "acetyl ester biosynthesis") -AnnotationAssertion(Annotation( "CHEBI:47622") "acetyl ester biosynthetic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1900620") -AnnotationAssertion(rdfs:label "acetate ester biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of fermentation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that stops, prevents or reduces the frequency, rate or extent of fermentation.") -AnnotationAssertion( "al") -AnnotationAssertion( "2012-06-15T08:21:31Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of fermentation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of fermentation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of fermentation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of fermentation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901003") -AnnotationAssertion(rdfs:label "negative regulation of fermentation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of calcium ion transmembrane transporter activity) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") "Any process that modulates the frequency, rate or extent of calcium ion transmembrane transporter activity.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2012-06-15T07:54:12Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901019") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "regulation of calcium ion transmembrane transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (negative regulation of calcium ion transmembrane transporter activity) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") "Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion transmembrane transporter activity.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2012-06-15T07:54:32Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of calcium ion transmembrane transporter activity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of calcium ion transmembrane transporter activity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of calcium ion transmembrane transporter activity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of calcium ion transmembrane transporter activity") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901020") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "negative regulation of calcium ion transmembrane transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of calcium ion transmembrane transporter activity) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") "Any process that activates or increases the frequency, rate or extent of calcium ion transmembrane transporter activity.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2012-06-15T07:54:40Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of calcium ion transmembrane transporter activity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of calcium ion transmembrane transporter activity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of calcium ion transmembrane transporter activity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of calcium ion transmembrane transporter activity") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901021") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "positive regulation of calcium ion transmembrane transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (glucosamine-containing compound metabolic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "The chemical reactions and pathways involving glucosamine-containing compounds (glucosamines).") -AnnotationAssertion( "bf") -AnnotationAssertion( "2012-07-02T03:18:04Z") -AnnotationAssertion(Annotation( "GOC:bf") "glucosamine-containing compound metabolism") -AnnotationAssertion(Annotation( "CHEBI:24271") "glucosamines metabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "glucosamines metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901071") -AnnotationAssertion(rdfs:label "glucosamine-containing compound metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (glucosamine-containing compound catabolic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "The chemical reactions and pathways resulting in the breakdown of glucosamine-containing compounds (glucosamines).") -AnnotationAssertion( "bf") -AnnotationAssertion( "2012-07-02T03:18:25Z") -AnnotationAssertion(Annotation( "GOC:bf") "glucosamine-containing compound breakdown") -AnnotationAssertion(Annotation( "GOC:bf") "glucosamine-containing compound catabolism") -AnnotationAssertion(Annotation( "GOC:bf") "glucosamine-containing compound degradation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "glucosamines breakdown") -AnnotationAssertion(Annotation( "CHEBI:24271") "glucosamines catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "glucosamines catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "glucosamines degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901072") -AnnotationAssertion(rdfs:label "glucosamine-containing compound catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (glucosamine-containing compound biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "The chemical reactions and pathways resulting in the formation of glucosamine-containing compounds (glucosamines).") -AnnotationAssertion( "bf") -AnnotationAssertion( "2012-07-02T03:18:33Z") -AnnotationAssertion(Annotation( "GOC:bf") "glucosamine-containing compound anabolism") -AnnotationAssertion(Annotation( "GOC:bf") "glucosamine-containing compound biosynthesis") -AnnotationAssertion(Annotation( "GOC:bf") "glucosamine-containing compound formation") -AnnotationAssertion(Annotation( "GOC:bf") "glucosamine-containing compound synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "glucosamines anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "glucosamines biosynthesis") -AnnotationAssertion(Annotation( "CHEBI:24271") "glucosamines biosynthetic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "glucosamines formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "glucosamines synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901073") -AnnotationAssertion(rdfs:label "glucosamine-containing compound biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (acetate ester metabolic process involved in fermentation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:sgd_curators") "Any acetate ester metabolic process that is involved in fermentation.") -AnnotationAssertion( "rb") -AnnotationAssertion( "2012-07-05T11:47:17Z") -AnnotationAssertion(Annotation( "GOC:sgd_curators") "acetate ester metabolic process during fermentation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901089") -AnnotationAssertion(rdfs:label "acetate ester metabolic process involved in fermentation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (carbohydrate derivative metabolic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "The chemical reactions and pathways involving carbohydrate derivative.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2012-07-12T04:05:09Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "carbohydrate derivative metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901135") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "carbohydrate derivative metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (carbohydrate derivative catabolic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "The chemical reactions and pathways resulting in the breakdown of carbohydrate derivative.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2012-07-12T04:05:31Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "carbohydrate derivative breakdown") -AnnotationAssertion(Annotation( "GOC:TermGenie") "carbohydrate derivative catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "carbohydrate derivative degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901136") -AnnotationAssertion(rdfs:label "carbohydrate derivative catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (carbohydrate derivative biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "The chemical reactions and pathways resulting in the formation of carbohydrate derivative.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2012-07-12T04:05:39Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "carbohydrate derivative anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "carbohydrate derivative biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "carbohydrate derivative formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "carbohydrate derivative synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901137") -AnnotationAssertion(rdfs:label "carbohydrate derivative biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (insulin metabolic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "The chemical reactions and pathways involving insulin.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "pm") -AnnotationAssertion( "2012-07-13T12:32:40Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "insulin metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901142") -AnnotationAssertion(rdfs:label "insulin metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) -SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) -SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) -DisjointClasses( ObjectSomeValuesFrom( )) -DisjointClasses( ObjectSomeValuesFrom( )) - -# Class: (insulin catabolic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "The chemical reactions and pathways resulting in the breakdown of insulin.") -AnnotationAssertion( "pm") -AnnotationAssertion( "2012-07-13T12:33:03Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "insulin breakdown") -AnnotationAssertion(Annotation( "GOC:TermGenie") "insulin catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "insulin degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901143") -AnnotationAssertion(rdfs:label "insulin catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (mesenchymal cell apoptotic process involved in nephron morphogenesis) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mtg_apoptosis") "Any mesenchymal cell apoptotic process that is involved in nephron morphogenesis.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2012-07-13T01:43:51Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901145") -AnnotationAssertion(rdfs:label "mesenchymal cell apoptotic process involved in nephron morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mtg_apoptosis") "Any mesenchymal cell apoptotic process that is involved in mesonephric nephron morphogenesis.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2012-07-13T02:40:43Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901146") -AnnotationAssertion(rdfs:label "mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mtg_apoptosis") "Any mesenchymal cell apoptotic process that is involved in metanephric nephron morphogenesis.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2012-07-13T02:41:12Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901147") -AnnotationAssertion(rdfs:label "mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (gene expression involved in extracellular matrix organization) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:pg") Annotation( "PMID:18668558") "Any gene expression that is involved in extracellular matrix organization. Gene expression includes both transcription to produce an RNA transcript, and the translation of that mRNA into protein. Protein maturation is included in gene expression when required to form an active form of a product from an inactive precursor form.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2012-07-16T03:29:30Z") -AnnotationAssertion(Annotation( "GOC:bf") "expression of extracellular matrix proteins") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:pg") "extracellular matrix protein production") -AnnotationAssertion( "GO:1901148") -AnnotationAssertion(rdfs:label "gene expression involved in extracellular matrix organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (primary amino compound metabolic process) AnnotationAssertion(Annotation( "GOC:TermGenie") "The chemical reactions and pathways involving primary amino compound.") @@ -117911,418 +27948,8 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:1901160") AnnotationAssertion(rdfs:label "primary amino compound metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (primary amino compound catabolic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "The chemical reactions and pathways resulting in the breakdown of primary amino compound.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2012-07-18T04:45:06Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "primary amino compound breakdown") -AnnotationAssertion(Annotation( "GOC:TermGenie") "primary amino compound catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "primary amino compound degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901161") -AnnotationAssertion(rdfs:label "primary amino compound catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (primary amino compound biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "The chemical reactions and pathways resulting in the formation of primary amino compound.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2012-07-18T04:45:14Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "primary amino compound anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "primary amino compound biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "primary amino compound formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "primary amino compound synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901162") -AnnotationAssertion(rdfs:label "primary amino compound biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of trophoblast cell migration) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") "Any process that modulates the frequency, rate or extent of trophoblast cell migration.") -AnnotationAssertion( "vk") -AnnotationAssertion( "2012-07-19T07:53:06Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901163") -AnnotationAssertion(rdfs:label "regulation of trophoblast cell migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of trophoblast cell migration) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") "Any process that stops, prevents or reduces the frequency, rate or extent of trophoblast cell migration.") -AnnotationAssertion( "vk") -AnnotationAssertion( "2012-07-19T07:53:28Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of trophoblast cell migration") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of trophoblast cell migration") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of trophoblast cell migration") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of trophoblast cell migration") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901164") -AnnotationAssertion(rdfs:label "negative regulation of trophoblast cell migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of trophoblast cell migration) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") "Any process that activates or increases the frequency, rate or extent of trophoblast cell migration.") -AnnotationAssertion( "vk") -AnnotationAssertion( "2012-07-19T07:53:35Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of trophoblast cell migration") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of trophoblast cell migration") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of trophoblast cell migration") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of trophoblast cell migration") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901165") -AnnotationAssertion(rdfs:label "positive regulation of trophoblast cell migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (neural crest cell migration involved in autonomic nervous system development) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") "Any neural crest cell migration that is involved in autonomic nervous system development.") -AnnotationAssertion( "vk") -AnnotationAssertion( "2012-07-19T08:39:56Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901166") -AnnotationAssertion(rdfs:label "neural crest cell migration involved in autonomic nervous system development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of formation of translation initiation ternary complex) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that modulates the frequency, rate or extent of formation of translation initiation ternary complex.") -AnnotationAssertion( "ss") -AnnotationAssertion( "2012-07-25T02:26:58Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of translation initiation ternary complex assembly") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901190") -AnnotationAssertion(rdfs:label "regulation of formation of translation initiation ternary complex") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of formation of translation initiation ternary complex) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that stops, prevents or reduces the frequency, rate or extent of formation of translation initiation ternary complex.") -AnnotationAssertion( "ss") -AnnotationAssertion( "2012-07-25T02:27:21Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of formation of translation initiation ternary complex") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of translation initiation ternary complex assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of formation of translation initiation ternary complex") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of translation initiation ternary complex assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of formation of translation initiation ternary complex") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of translation initiation ternary complex assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of translation initiation ternary complex assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of translation initiation ternary complex assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of formation of translation initiation ternary complex") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901191") -AnnotationAssertion(rdfs:label "negative regulation of formation of translation initiation ternary complex") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of formation of translation initiation ternary complex) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that activates or increases the frequency, rate or extent of formation of translation initiation ternary complex.") -AnnotationAssertion( "ss") -AnnotationAssertion( "2012-07-25T02:27:29Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of translation initiation ternary complex assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of translation initiation ternary complex assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of formation of translation initiation ternary complex") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of translation initiation ternary complex assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of formation of translation initiation ternary complex") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of translation initiation ternary complex assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of formation of translation initiation ternary complex") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of translation initiation ternary complex assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of formation of translation initiation ternary complex") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901192") -AnnotationAssertion(rdfs:label "positive regulation of formation of translation initiation ternary complex") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of extracellular matrix assembly) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") "Any process that modulates the frequency, rate or extent of extracellular matrix assembly.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2012-07-27T04:04:00Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901201") -AnnotationAssertion(rdfs:label "regulation of extracellular matrix assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (negative regulation of extracellular matrix assembly) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") "Any process that stops, prevents or reduces the frequency, rate or extent of extracellular matrix assembly.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2012-07-27T04:04:24Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of extracellular matrix assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of extracellular matrix assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of extracellular matrix assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of extracellular matrix assembly") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901202") -AnnotationAssertion(rdfs:label "negative regulation of extracellular matrix assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of extracellular matrix assembly) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") "Any process that activates or increases the frequency, rate or extent of extracellular matrix assembly.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2012-07-27T04:04:32Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of extracellular matrix assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of extracellular matrix assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of extracellular matrix assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of extracellular matrix assembly") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901203") -AnnotationAssertion(rdfs:label "positive regulation of extracellular matrix assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (regulation of cardiac chamber formation) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") "Any process that modulates the frequency, rate or extent of cardiac chamber formation.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2012-07-31T07:18:35Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of heart chamber formation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901210") -AnnotationAssertion(rdfs:label "regulation of cardiac chamber formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of cardiac chamber formation) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") "Any process that stops, prevents or reduces the frequency, rate or extent of cardiac chamber formation.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2012-07-31T07:18:57Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of cardiac chamber formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of heart chamber formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of cardiac chamber formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of heart chamber formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of cardiac chamber formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of heart chamber formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of heart chamber formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of heart chamber formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of cardiac chamber formation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901211") -AnnotationAssertion(rdfs:label "negative regulation of cardiac chamber formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of cardiac chamber formation) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") "Any process that activates or increases the frequency, rate or extent of cardiac chamber formation.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2012-07-31T07:19:05Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of heart chamber formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of heart chamber formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of cardiac chamber formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of heart chamber formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of cardiac chamber formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of heart chamber formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of cardiac chamber formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of heart chamber formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of cardiac chamber formation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901212") -AnnotationAssertion(rdfs:label "positive regulation of cardiac chamber formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (regulation of cardiac chamber morphogenesis) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") "Any process that modulates the frequency, rate or extent of cardiac chamber morphogenesis.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2012-08-06T17:59:11Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of heart chamber morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901219") -AnnotationAssertion(rdfs:label "regulation of cardiac chamber morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (negative regulation of cardiac chamber morphogenesis) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") "Any process that stops, prevents or reduces the frequency, rate or extent of cardiac chamber morphogenesis.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2012-08-06T17:59:34Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of cardiac chamber morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of heart chamber morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of cardiac chamber morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of heart chamber morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of cardiac chamber morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of heart chamber morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of heart chamber morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of cardiac chamber morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of heart chamber morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901220") -AnnotationAssertion(rdfs:label "negative regulation of cardiac chamber morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of cardiac chamber morphogenesis) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") "Any process that activates or increases the frequency, rate or extent of cardiac chamber morphogenesis.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2012-08-06T17:59:42Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of heart chamber morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of cardiac chamber morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of heart chamber morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of cardiac chamber morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of heart chamber morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of cardiac chamber morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of heart chamber morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of cardiac chamber morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of heart chamber morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901221") -AnnotationAssertion(rdfs:label "positive regulation of cardiac chamber morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of lung ciliated cell differentiation) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") "Any process that modulates the frequency, rate or extent of lung ciliated cell differentiation.") -AnnotationAssertion( "vk") -AnnotationAssertion( "2012-08-08T08:58:34Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901246") -AnnotationAssertion(rdfs:label "regulation of lung ciliated cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of lung ciliated cell differentiation) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") "Any process that stops, prevents or reduces the frequency, rate or extent of lung ciliated cell differentiation.") -AnnotationAssertion( "vk") -AnnotationAssertion( "2012-08-08T08:58:58Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of lung ciliated cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of lung ciliated cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of lung ciliated cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of lung ciliated cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901247") -AnnotationAssertion(rdfs:label "negative regulation of lung ciliated cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of lung ciliated cell differentiation) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") "Any process that activates or increases the frequency, rate or extent of lung ciliated cell differentiation.") -AnnotationAssertion( "vk") -AnnotationAssertion( "2012-08-08T08:59:05Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of lung ciliated cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of lung ciliated cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of lung ciliated cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of lung ciliated cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901248") -AnnotationAssertion(rdfs:label "positive regulation of lung ciliated cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (regulation of lung goblet cell differentiation) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") "Any process that modulates the frequency, rate or extent of lung goblet cell differentiation.") -AnnotationAssertion( "vk") -AnnotationAssertion( "2012-08-08T08:59:12Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of pulmonary goblet cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901249") -AnnotationAssertion(rdfs:label "regulation of lung goblet cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of lung goblet cell differentiation) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") "Any process that stops, prevents or reduces the frequency, rate or extent of lung goblet cell differentiation.") -AnnotationAssertion( "vk") -AnnotationAssertion( "2012-08-08T08:59:36Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of lung goblet cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of pulmonary goblet cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of lung goblet cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of pulmonary goblet cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of lung goblet cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of pulmonary goblet cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of pulmonary goblet cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of lung goblet cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of pulmonary goblet cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901250") -AnnotationAssertion(rdfs:label "negative regulation of lung goblet cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of lung goblet cell differentiation) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") "Any process that activates or increases the frequency, rate or extent of lung goblet cell differentiation.") -AnnotationAssertion( "vk") -AnnotationAssertion( "2012-08-08T08:59:44Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of pulmonary goblet cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of lung goblet cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of pulmonary goblet cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of lung goblet cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of pulmonary goblet cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of lung goblet cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of pulmonary goblet cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of lung goblet cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of pulmonary goblet cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901251") -AnnotationAssertion(rdfs:label "positive regulation of lung goblet cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (carbohydrate derivative transport) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:bf") Annotation( "GOC:jl") "The directed movement of a carbohydrate derivative into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2012-08-16T14:51:22Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901264") -AnnotationAssertion(rdfs:label "carbohydrate derivative transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (nucleoside phosphate binding) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Binding to nucleoside phosphate.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2012-08-17T12:59:58Z") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:1901265") -AnnotationAssertion(rdfs:label "nucleoside phosphate binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (nucleoside phosphate catabolic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "The chemical reactions and pathways resulting in the breakdown of a nucleoside phosphate.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2012-08-20T12:33:25Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "nucleoside phosphate breakdown") -AnnotationAssertion(Annotation( "GOC:TermGenie") "nucleoside phosphate catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "nucleoside phosphate degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901292") -AnnotationAssertion(rdfs:label "nucleoside phosphate catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (nucleoside phosphate biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "The chemical reactions and pathways resulting in the formation of a nucleoside phosphate.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2012-08-20T12:33:45Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "nucleoside phosphate anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "nucleoside phosphate biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "nucleoside phosphate formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "nucleoside phosphate synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901293") -AnnotationAssertion(rdfs:label "nucleoside phosphate biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (regulation of flagellated sperm motility) AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:cilia") Annotation( "GOC:krc") "Any process that modulates the frequency, rate or extent of flagellated sperm motility.") @@ -118333,113 +27960,8 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:1901317") AnnotationAssertion(rdfs:label "regulation of flagellated sperm motility") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (negative regulation of flagellated sperm motility) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:cilia") Annotation( "GOC:krc") "Any process that stops, prevents or reduces the frequency, rate or extent of flagellated sperm motility.") -AnnotationAssertion( "hjd") -AnnotationAssertion( "2012-08-22T20:50:35Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of sperm motility") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of sperm movement") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of sperm motility") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of sperm movement") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of sperm motility") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of sperm movement") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of sperm movement") -AnnotationAssertion( "negative regulation of sperm motility") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of sperm movement") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of sperm motility") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901318") -AnnotationAssertion(rdfs:label "negative regulation of flagellated sperm motility") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of odontoblast differentiation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that modulates the frequency, rate or extent of odontoblast differentiation.") -AnnotationAssertion( "hjd") -AnnotationAssertion( "2012-08-31T16:50:05Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901329") -AnnotationAssertion(rdfs:label "regulation of odontoblast differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of odontoblast differentiation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that stops, prevents or reduces the frequency, rate or extent of odontoblast differentiation.") -AnnotationAssertion( "hjd") -AnnotationAssertion( "2012-08-31T16:50:27Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of odontoblast differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of odontoblast differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of odontoblast differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of odontoblast differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901330") -AnnotationAssertion(rdfs:label "negative regulation of odontoblast differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of odontoblast differentiation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that activates or increases the frequency, rate or extent of odontoblast differentiation.") -AnnotationAssertion( "hjd") -AnnotationAssertion( "2012-08-31T16:50:35Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of odontoblast differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of odontoblast differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of odontoblast differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of odontoblast differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901331") -AnnotationAssertion(rdfs:label "positive regulation of odontoblast differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (catecholamine binding) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Binding to catecholamine.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2012-09-03T14:08:44Z") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:1901338") -AnnotationAssertion(rdfs:label "catecholamine binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of vasculature development) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that modulates the frequency, rate or extent of vasculature development.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2012-09-06T09:16:15Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of vascular system development") -AnnotationAssertion( "GO:1901342") -AnnotationAssertion(rdfs:label "regulation of vasculature development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (negative regulation of vasculature development) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that stops, prevents or reduces the frequency, rate or extent of vasculature development.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2012-09-06T09:17:24Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of vasculature development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of vasculature development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of vasculature development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of vasculature development") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of vascular system development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of vascular system development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of vascular system development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of vascular system development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of vascular system development") -AnnotationAssertion( "GO:1901343") -AnnotationAssertion(rdfs:label "negative regulation of vasculature development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - # Class: (organic cyclic compound metabolic process) AnnotationAssertion(Annotation( "GOC:TermGenie") "The chemical reactions and pathways involving organic cyclic compound.") @@ -118449,22 +27971,8 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:1901360") AnnotationAssertion(rdfs:label "organic cyclic compound metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (organic cyclic compound catabolic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "The chemical reactions and pathways resulting in the breakdown of organic cyclic compound.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2012-09-14T09:05:04Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "organic cyclic compound breakdown") -AnnotationAssertion(Annotation( "GOC:TermGenie") "organic cyclic compound catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "organic cyclic compound degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901361") -AnnotationAssertion(rdfs:label "organic cyclic compound catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (organic cyclic compound biosynthetic process) AnnotationAssertion(Annotation( "GOC:TermGenie") "The chemical reactions and pathways resulting in the formation of organic cyclic compound.") @@ -118477,692 +27985,9 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:1901362") AnnotationAssertion(rdfs:label "organic cyclic compound biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) -# Class: (heterocyclic compound binding) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Binding to heterocyclic compound.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2012-09-14T13:53:50Z") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:1901363") -AnnotationAssertion(rdfs:label "heterocyclic compound binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (acetate ester transport) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "The directed movement of an acetate ester into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2012-09-28T10:42:13Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901374") -AnnotationAssertion(rdfs:label "acetate ester transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (acetate ester transmembrane transporter activity) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Enables the transfer of an acetate ester from one side of a membrane to the other.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2012-09-28T10:47:08Z") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:1901375") -AnnotationAssertion(rdfs:label "acetate ester transmembrane transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (regulation of chorionic trophoblast cell proliferation) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") "Any process that modulates the frequency, rate or extent of chorionic trophoblast cell proliferation.") -AnnotationAssertion( "vk") -AnnotationAssertion( "2012-10-01T10:03:13Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901382") -AnnotationAssertion(rdfs:label "regulation of chorionic trophoblast cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of chorionic trophoblast cell proliferation) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") "Any process that stops, prevents or reduces the frequency, rate or extent of chorionic trophoblast cell proliferation.") -AnnotationAssertion( "vk") -AnnotationAssertion( "2012-10-01T10:04:23Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of chorionic trophoblast cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of chorionic trophoblast cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of chorionic trophoblast cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of chorionic trophoblast cell proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901383") -AnnotationAssertion(rdfs:label "negative regulation of chorionic trophoblast cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of chorionic trophoblast cell proliferation) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") "Any process that activates or increases the frequency, rate or extent of chorionic trophoblast cell proliferation.") -AnnotationAssertion( "vk") -AnnotationAssertion( "2012-10-01T10:04:41Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of chorionic trophoblast cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of chorionic trophoblast cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of chorionic trophoblast cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of chorionic trophoblast cell proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901384") -AnnotationAssertion(rdfs:label "positive regulation of chorionic trophoblast cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of tetrapyrrole metabolic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mengo_curators") "Any process that modulates the frequency, rate or extent of tetrapyrrole metabolic process.") -AnnotationAssertion( "tt") -AnnotationAssertion( "2012-10-01T14:34:03Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of tetrapyrrole metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901401") -AnnotationAssertion(rdfs:label "regulation of tetrapyrrole metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of tetrapyrrole metabolic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mengo_curators") "Any process that stops, prevents or reduces the frequency, rate or extent of tetrapyrrole metabolic process.") -AnnotationAssertion( "tt") -AnnotationAssertion( "2012-10-01T14:35:11Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of tetrapyrrole metabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of tetrapyrrole metabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of tetrapyrrole metabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of tetrapyrrole metabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of tetrapyrrole metabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of tetrapyrrole metabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of tetrapyrrole metabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of tetrapyrrole metabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of tetrapyrrole metabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901402") -AnnotationAssertion(rdfs:label "negative regulation of tetrapyrrole metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of tetrapyrrole metabolic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mengo_curators") "Any process that activates or increases the frequency, rate or extent of tetrapyrrole metabolic process.") -AnnotationAssertion( "tt") -AnnotationAssertion( "2012-10-01T14:35:29Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of tetrapyrrole metabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of tetrapyrrole metabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of tetrapyrrole metabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of tetrapyrrole metabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of tetrapyrrole metabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of tetrapyrrole metabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of tetrapyrrole metabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of tetrapyrrole metabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of tetrapyrrole metabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901403") -AnnotationAssertion(rdfs:label "positive regulation of tetrapyrrole metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of tetrapyrrole catabolic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mengo_curators") "Any process that modulates the frequency, rate or extent of tetrapyrrole catabolic process.") -AnnotationAssertion( "tt") -AnnotationAssertion( "2012-10-01T14:38:12Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of tetrapyrrole breakdown") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of tetrapyrrole catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of tetrapyrrole degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901404") -AnnotationAssertion(rdfs:label "regulation of tetrapyrrole catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of tetrapyrrole catabolic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mengo_curators") "Any process that stops, prevents or reduces the frequency, rate or extent of tetrapyrrole catabolic process.") -AnnotationAssertion( "tt") -AnnotationAssertion( "2012-10-01T14:39:22Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of tetrapyrrole breakdown") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of tetrapyrrole catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of tetrapyrrole catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of tetrapyrrole degradation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of tetrapyrrole breakdown") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of tetrapyrrole catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of tetrapyrrole catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of tetrapyrrole degradation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of tetrapyrrole breakdown") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of tetrapyrrole catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of tetrapyrrole catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of tetrapyrrole degradation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of tetrapyrrole breakdown") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of tetrapyrrole catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of tetrapyrrole degradation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of tetrapyrrole breakdown") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of tetrapyrrole catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of tetrapyrrole degradation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of tetrapyrrole catabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901405") -AnnotationAssertion(rdfs:label "negative regulation of tetrapyrrole catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of tetrapyrrole catabolic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mengo_curators") "Any process that activates or increases the frequency, rate or extent of tetrapyrrole catabolic process.") -AnnotationAssertion( "tt") -AnnotationAssertion( "2012-10-01T14:39:40Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of tetrapyrrole breakdown") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of tetrapyrrole catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of tetrapyrrole degradation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of tetrapyrrole breakdown") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of tetrapyrrole catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of tetrapyrrole degradation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of tetrapyrrole breakdown") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of tetrapyrrole catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of tetrapyrrole catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of tetrapyrrole degradation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of tetrapyrrole breakdown") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of tetrapyrrole catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of tetrapyrrole catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of tetrapyrrole degradation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of tetrapyrrole breakdown") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of tetrapyrrole catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of tetrapyrrole catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of tetrapyrrole degradation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of tetrapyrrole catabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901406") -AnnotationAssertion(rdfs:label "positive regulation of tetrapyrrole catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of tetrapyrrole biosynthetic process from glutamate) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mengo_curators") "Any process that modulates the frequency, rate or extent of tetrapyrrole biosynthetic process from glutamate.") -AnnotationAssertion( "tt") -AnnotationAssertion( "2012-10-01T16:20:56Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of tetrapyrrole anabolism from glutamate") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of tetrapyrrole biosynthesis from glutamate") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of tetrapyrrole formation from glutamate") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of tetrapyrrole synthesis from glutamate") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901410") -AnnotationAssertion(rdfs:label "regulation of tetrapyrrole biosynthetic process from glutamate") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of tetrapyrrole biosynthetic process from glutamate) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mengo_curators") "Any process that stops, prevents or reduces the frequency, rate or extent of tetrapyrrole biosynthetic process from glutamate.") -AnnotationAssertion( "tt") -AnnotationAssertion( "2012-10-01T16:22:03Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of tetrapyrrole anabolism from glutamate") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of tetrapyrrole biosynthesis from glutamate") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of tetrapyrrole biosynthetic process from glutamate") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of tetrapyrrole formation from glutamate") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of tetrapyrrole synthesis from glutamate") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of tetrapyrrole anabolism from glutamate") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of tetrapyrrole biosynthesis from glutamate") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of tetrapyrrole biosynthetic process from glutamate") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of tetrapyrrole formation from glutamate") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of tetrapyrrole synthesis from glutamate") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of tetrapyrrole anabolism from glutamate") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of tetrapyrrole biosynthesis from glutamate") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of tetrapyrrole biosynthetic process from glutamate") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of tetrapyrrole formation from glutamate") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of tetrapyrrole synthesis from glutamate") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of tetrapyrrole anabolism from glutamate") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of tetrapyrrole biosynthesis from glutamate") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of tetrapyrrole formation from glutamate") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of tetrapyrrole synthesis from glutamate") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of tetrapyrrole anabolism from glutamate") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of tetrapyrrole biosynthesis from glutamate") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of tetrapyrrole formation from glutamate") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of tetrapyrrole synthesis from glutamate") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of tetrapyrrole biosynthetic process from glutamate") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901411") -AnnotationAssertion(rdfs:label "negative regulation of tetrapyrrole biosynthetic process from glutamate") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of tetrapyrrole biosynthetic process from glutamate) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mengo_curators") "Any process that activates or increases the frequency, rate or extent of tetrapyrrole biosynthetic process from glutamate.") -AnnotationAssertion( "tt") -AnnotationAssertion( "2012-10-01T16:22:21Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of tetrapyrrole anabolism from glutamate") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of tetrapyrrole biosynthesis from glutamate") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of tetrapyrrole formation from glutamate") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of tetrapyrrole synthesis from glutamate") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of tetrapyrrole anabolism from glutamate") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of tetrapyrrole biosynthesis from glutamate") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of tetrapyrrole formation from glutamate") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of tetrapyrrole synthesis from glutamate") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of tetrapyrrole anabolism from glutamate") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of tetrapyrrole biosynthesis from glutamate") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of tetrapyrrole biosynthetic process from glutamate") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of tetrapyrrole formation from glutamate") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of tetrapyrrole synthesis from glutamate") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of tetrapyrrole anabolism from glutamate") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of tetrapyrrole biosynthesis from glutamate") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of tetrapyrrole biosynthetic process from glutamate") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of tetrapyrrole formation from glutamate") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of tetrapyrrole synthesis from glutamate") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of tetrapyrrole anabolism from glutamate") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of tetrapyrrole biosynthesis from glutamate") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of tetrapyrrole biosynthetic process from glutamate") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of tetrapyrrole formation from glutamate") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of tetrapyrrole synthesis from glutamate") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of tetrapyrrole biosynthetic process from glutamate") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901412") -AnnotationAssertion(rdfs:label "positive regulation of tetrapyrrole biosynthetic process from glutamate") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of response to alcohol) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mengo_curators") "Any process that modulates the frequency, rate or extent of response to alcohol.") -AnnotationAssertion( "tt") -AnnotationAssertion( "2012-10-01T16:52:13Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901419") -AnnotationAssertion(rdfs:label "regulation of response to alcohol") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of response to alcohol) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mengo_curators") "Any process that stops, prevents or reduces the frequency, rate or extent of response to alcohol.") -AnnotationAssertion( "tt") -AnnotationAssertion( "2012-10-01T16:53:25Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of response to alcohol") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of response to alcohol") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of response to alcohol") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of response to alcohol") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901420") -AnnotationAssertion(rdfs:label "negative regulation of response to alcohol") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of response to alcohol) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mengo_curators") "Any process that activates or increases the frequency, rate or extent of response to alcohol.") -AnnotationAssertion( "tt") -AnnotationAssertion( "2012-10-01T16:53:42Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of response to alcohol") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of response to alcohol") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of response to alcohol") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of response to alcohol") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901421") -AnnotationAssertion(rdfs:label "positive regulation of response to alcohol") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (response to formic acid) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mengo_curators") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a formic acid stimulus.") -AnnotationAssertion( "tt") -AnnotationAssertion( "2012-10-01T18:43:05Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901425") -AnnotationAssertion(rdfs:label "response to formic acid") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of response to acetate) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mengo_curators") "Any process that modulates the frequency, rate or extent of response to acetate.") -AnnotationAssertion( "tt") -AnnotationAssertion( "2012-10-02T14:25:06Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901457") -AnnotationAssertion(rdfs:label "regulation of response to acetate") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of response to acetate) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mengo_curators") "Any process that stops, prevents or reduces the frequency, rate or extent of response to acetate.") -AnnotationAssertion( "tt") -AnnotationAssertion( "2012-10-02T14:26:15Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of response to acetate") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of response to acetate") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of response to acetate") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of response to acetate") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901458") -AnnotationAssertion(rdfs:label "negative regulation of response to acetate") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of response to acetate) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mengo_curators") "Any process that activates or increases the frequency, rate or extent of response to acetate.") -AnnotationAssertion( "tt") -AnnotationAssertion( "2012-10-02T14:26:34Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of response to acetate") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of response to acetate") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of response to acetate") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of response to acetate") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901459") -AnnotationAssertion(rdfs:label "positive regulation of response to acetate") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of response to formic acid) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mengo_curators") "Any process that modulates the frequency, rate or extent of response to formic acid.") -AnnotationAssertion( "tt") -AnnotationAssertion( "2012-10-02T14:27:54Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901460") -AnnotationAssertion(rdfs:label "regulation of response to formic acid") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of response to formic acid) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mengo_curators") "Any process that stops, prevents or reduces the frequency, rate or extent of response to formic acid.") -AnnotationAssertion( "tt") -AnnotationAssertion( "2012-10-02T14:29:02Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of response to formic acid") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of response to formic acid") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of response to formic acid") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of response to formic acid") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901461") -AnnotationAssertion(rdfs:label "negative regulation of response to formic acid") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of response to formic acid) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mengo_curators") "Any process that activates or increases the frequency, rate or extent of response to formic acid.") -AnnotationAssertion( "tt") -AnnotationAssertion( "2012-10-02T14:29:20Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of response to formic acid") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of response to formic acid") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of response to formic acid") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of response to formic acid") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901462") -AnnotationAssertion(rdfs:label "positive regulation of response to formic acid") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of tetrapyrrole biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mengo_curators") "Any process that modulates the frequency, rate or extent of tetrapyrrole biosynthetic process.") -AnnotationAssertion( "tt") -AnnotationAssertion( "2012-10-02T14:34:14Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of tetrapyrrole anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of tetrapyrrole biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of tetrapyrrole formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of tetrapyrrole synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901463") -AnnotationAssertion(rdfs:label "regulation of tetrapyrrole biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of tetrapyrrole biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mengo_curators") "Any process that stops, prevents or reduces the frequency, rate or extent of tetrapyrrole biosynthetic process.") -AnnotationAssertion( "tt") -AnnotationAssertion( "2012-10-02T14:35:26Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of tetrapyrrole anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of tetrapyrrole biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of tetrapyrrole biosynthetic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of tetrapyrrole formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of tetrapyrrole synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of tetrapyrrole anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of tetrapyrrole biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of tetrapyrrole biosynthetic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of tetrapyrrole formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of tetrapyrrole synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of tetrapyrrole anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of tetrapyrrole biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of tetrapyrrole biosynthetic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of tetrapyrrole formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of tetrapyrrole synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of tetrapyrrole anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of tetrapyrrole biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of tetrapyrrole formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of tetrapyrrole synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of tetrapyrrole anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of tetrapyrrole biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of tetrapyrrole formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of tetrapyrrole synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of tetrapyrrole biosynthetic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901464") -AnnotationAssertion(rdfs:label "negative regulation of tetrapyrrole biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of tetrapyrrole biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mengo_curators") "Any process that activates or increases the frequency, rate or extent of tetrapyrrole biosynthetic process.") -AnnotationAssertion( "tt") -AnnotationAssertion( "2012-10-02T14:35:43Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of tetrapyrrole anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of tetrapyrrole biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of tetrapyrrole formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of tetrapyrrole synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of tetrapyrrole anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of tetrapyrrole biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of tetrapyrrole formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of tetrapyrrole synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of tetrapyrrole anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of tetrapyrrole biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of tetrapyrrole biosynthetic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of tetrapyrrole formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of tetrapyrrole synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of tetrapyrrole anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of tetrapyrrole biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of tetrapyrrole biosynthetic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of tetrapyrrole formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of tetrapyrrole synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of tetrapyrrole anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of tetrapyrrole biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of tetrapyrrole biosynthetic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of tetrapyrrole formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of tetrapyrrole synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of tetrapyrrole biosynthetic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901465") -AnnotationAssertion(rdfs:label "positive regulation of tetrapyrrole biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of Golgi calcium ion export) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that modulates the frequency, rate or extent of Golgi calcium ion export.") -AnnotationAssertion( "al") -AnnotationAssertion( "2012-10-03T07:26:03Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901472") -AnnotationAssertion(rdfs:label "regulation of Golgi calcium ion export") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (azole transmembrane transporter activity) - -AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:3527307206") Annotation( "Wikipedia:Azole") "Enables the directed movement of azoles, heterocyclic compound found in many biologically important substances, from one side of a membrane to the other.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2012-10-04T20:00:27Z") -AnnotationAssertion( "GO:0045118") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "azole transporter activity") -AnnotationAssertion( "GO:1901474") -AnnotationAssertion(rdfs:label "azole transmembrane transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (regulation of lymphangiogenesis) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:dph") Annotation( "PMID:20133819") "Any process that modulates the frequency, rate or extent of lymphangiogenesis.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2012-10-15T13:08:17Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of lymph vessel formation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901490") -AnnotationAssertion(rdfs:label "regulation of lymphangiogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of lymphangiogenesis) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:dph") Annotation( "PMID:20133819") "Any process that stops, prevents or reduces the frequency, rate or extent of lymphangiogenesis.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2012-10-15T13:08:21Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of lymph vessel formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of lymphangiogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of lymph vessel formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of lymphangiogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of lymph vessel formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of lymphangiogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of lymph vessel formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of lymph vessel formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of lymphangiogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901491") -AnnotationAssertion(rdfs:label "negative regulation of lymphangiogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of lymphangiogenesis) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:dph") Annotation( "PMID:20133819") "Any process that activates or increases the frequency, rate or extent of lymphangiogenesis.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2012-10-15T13:08:25Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of lymph vessel formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of lymph vessel formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of lymphangiogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of lymph vessel formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of lymphangiogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of lymph vessel formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of lymphangiogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of lymph vessel formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of lymphangiogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901492") -AnnotationAssertion(rdfs:label "positive regulation of lymphangiogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (carbohydrate derivative transmembrane transporter activity) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:pr") "Enables the transfer of carbohydrate derivative from one side of a membrane to the other.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2012-10-17T10:31:22Z") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "carbohydrate derivative transporter activity") -AnnotationAssertion( "GO:1901505") -AnnotationAssertion(rdfs:label "carbohydrate derivative transmembrane transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "GO_REF:0000090") ObjectSomeValuesFrom( )) - -# Class: (regulation of endothelial tube morphogenesis) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:dph") "Any process that modulates the frequency, rate or extent of endothelial tube morphogenesis.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2012-10-17T14:30:40Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901509") -AnnotationAssertion(rdfs:label "regulation of endothelial tube morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of hematopoietic progenitor cell differentiation) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") "Any process that modulates the frequency, rate or extent of hematopoietic progenitor cell differentiation.") -AnnotationAssertion( "vk") -AnnotationAssertion( "2012-10-24T11:23:01Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of haematopoietic progenitor cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of haemopoietic progenitor cell differentiation") -AnnotationAssertion( "regulation of hemopoietic progenitor cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901532") -AnnotationAssertion(rdfs:label "regulation of hematopoietic progenitor cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of hematopoietic progenitor cell differentiation) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") "Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic progenitor cell differentiation.") -AnnotationAssertion( "vk") -AnnotationAssertion( "2012-10-24T11:23:06Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of haematopoietic progenitor cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of haemopoietic progenitor cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of hemopoietic progenitor cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of haematopoietic progenitor cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of haemopoietic progenitor cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of hemopoietic progenitor cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of haematopoietic progenitor cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of haemopoietic progenitor cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of hemopoietic progenitor cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of haematopoietic progenitor cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of haemopoietic progenitor cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of haematopoietic progenitor cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of haemopoietic progenitor cell differentiation") -AnnotationAssertion( "negative regulation of hemopoietic progenitor cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of hemopoietic progenitor cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of hematopoietic progenitor cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of hematopoietic progenitor cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of hematopoietic progenitor cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of hematopoietic progenitor cell differentiation") -AnnotationAssertion( "GO:1901533") -AnnotationAssertion(rdfs:label "negative regulation of hematopoietic progenitor cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of hematopoietic progenitor cell differentiation) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") "Any process that activates or increases the frequency, rate or extent of hematopoietic progenitor cell differentiation.") -AnnotationAssertion( "vk") -AnnotationAssertion( "2012-10-24T11:23:14Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of haematopoietic progenitor cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of haemopoietic progenitor cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of haematopoietic progenitor cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of haemopoietic progenitor cell differentiation") -AnnotationAssertion( "positive regulation of hemopoietic progenitor cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of haematopoietic progenitor cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of haemopoietic progenitor cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of hemopoietic progenitor cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of haematopoietic progenitor cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of haemopoietic progenitor cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of hemopoietic progenitor cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of haematopoietic progenitor cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of haemopoietic progenitor cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of hemopoietic progenitor cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of hemopoietic progenitor cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of hematopoietic progenitor cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of hematopoietic progenitor cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of hematopoietic progenitor cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of hematopoietic progenitor cell differentiation") -AnnotationAssertion( "GO:1901534") -AnnotationAssertion(rdfs:label "positive regulation of hematopoietic progenitor cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of endothelial cell development) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:pr") Annotation( "PMID:19470579") "Any process that modulates the frequency, rate or extent of endothelial cell development.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2012-10-30T12:59:50Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901550") -AnnotationAssertion(rdfs:label "regulation of endothelial cell development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (negative regulation of endothelial cell development) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:pr") Annotation( "PMID:19470579") "Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell development.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2012-10-30T12:59:54Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of endothelial cell development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of endothelial cell development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of endothelial cell development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of endothelial cell development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901551") -AnnotationAssertion(rdfs:label "negative regulation of endothelial cell development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of endothelial cell development) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:pr") Annotation( "PMID:19470579") "Any process that activates or increases the frequency, rate or extent of endothelial cell development.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2012-10-30T12:59:58Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of endothelial cell development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of endothelial cell development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of endothelial cell development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of endothelial cell development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901552") -AnnotationAssertion(rdfs:label "positive regulation of endothelial cell development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (organonitrogen compound metabolic process) AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:pr") "The chemical reactions and pathways involving organonitrogen compound.") @@ -119172,23 +27997,9 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:1901564") AnnotationAssertion(rdfs:label "organonitrogen compound metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) -# Class: (organonitrogen compound catabolic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:pr") "The chemical reactions and pathways resulting in the breakdown of organonitrogen compound.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2012-11-04T15:17:56Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "organonitrogen compound breakdown") -AnnotationAssertion(Annotation( "GOC:TermGenie") "organonitrogen compound catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "organonitrogen compound degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901565") -AnnotationAssertion(rdfs:label "organonitrogen compound catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (organonitrogen compound biosynthetic process) AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:pr") "The chemical reactions and pathways resulting in the formation of organonitrogen compound.") @@ -119201,29 +28012,9 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:1901566") AnnotationAssertion(rdfs:label "organonitrogen compound biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) -# Class: (organic substance catabolic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:pr") "The chemical reactions and pathways resulting in the breakdown of an organic substance, any molecular entity containing carbon.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2012-11-05T11:04:36Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "organic molecular entity breakdown") -AnnotationAssertion( "organic molecular entity catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "organic molecular entity catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "organic molecular entity degradation") -AnnotationAssertion( "organic substance breakdown") -AnnotationAssertion( "organic substance catabolism") -AnnotationAssertion( "organic substance degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901575") -AnnotationAssertion(rdfs:label "organic substance catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - # Class: (organic substance biosynthetic process) AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:pr") "The chemical reactions and pathways resulting in the formation of an organic substance, any molecular entity containing carbon.") @@ -119241,122 +28032,9 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:1901576") AnnotationAssertion(rdfs:label "organic substance biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) -# Class: (regulation of alkane biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that modulates the frequency, rate or extent of alkane biosynthetic process.") -AnnotationAssertion( "dhl") -AnnotationAssertion( "2012-11-05T21:54:06Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of alkane anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of alkane biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of alkane formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of alkane synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901577") -AnnotationAssertion(rdfs:label "regulation of alkane biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of alkane biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that stops, prevents or reduces the frequency, rate or extent of alkane biosynthetic process.") -AnnotationAssertion( "dhl") -AnnotationAssertion( "2012-11-05T21:54:11Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of alkane anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of alkane biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of alkane biosynthetic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of alkane formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of alkane synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of alkane anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of alkane biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of alkane biosynthetic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of alkane formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of alkane synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of alkane anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of alkane biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of alkane biosynthetic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of alkane formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of alkane synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of alkane anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of alkane biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of alkane formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of alkane synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of alkane anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of alkane biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of alkane formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of alkane synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of alkane biosynthetic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901578") -AnnotationAssertion(rdfs:label "negative regulation of alkane biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of alkane biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that activates or increases the frequency, rate or extent of alkane biosynthetic process.") -AnnotationAssertion( "dhl") -AnnotationAssertion( "2012-11-05T21:54:19Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of alkane anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of alkane biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of alkane formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of alkane synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of alkane anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of alkane biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of alkane formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of alkane synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of alkane anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of alkane biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of alkane biosynthetic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of alkane formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of alkane synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of alkane anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of alkane biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of alkane biosynthetic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of alkane formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of alkane synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of alkane anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of alkane biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of alkane biosynthetic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of alkane formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of alkane synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of alkane biosynthetic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901579") -AnnotationAssertion(rdfs:label "positive regulation of alkane biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (dendritic microtubule) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "NIF_Subcellular:sao110773650") "Any microtubule in a dendrite, a neuron projection.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2012-11-07T14:37:30Z") -AnnotationAssertion( "NIF_Subcellular:sao110773650") -AnnotationAssertion(Annotation( "GOC:TermGenie") "microtubule of dendrite") -AnnotationAssertion(Annotation( "GOC:TermGenie") "microtubulus of dendrite") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:1901588") -AnnotationAssertion(rdfs:label "dendritic microtubule") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (axon microtubule bundle) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "NIF_Subcellular:sao707332678") "An arrangement of closely apposed microtubules running parallel to each other in the axon hillock and initial segment.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2012-11-07T15:37:12Z") -AnnotationAssertion( "NIF_Subcellular:sao707332678") -AnnotationAssertion( "axon microtubule fascicle") -AnnotationAssertion(Annotation( "GOC:TermGenie") "microtubule bundle of axon") -AnnotationAssertion(Annotation( "GOC:TermGenie") "microtubule fascicle of axon") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:1901589") -AnnotationAssertion(rdfs:label "axon microtubule bundle") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (alpha-amino acid metabolic process) AnnotationAssertion(Annotation( "GOC:TermGenie") "The chemical reactions and pathways involving an alpha-amino acid.") @@ -119366,86 +28044,8 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:1901605") AnnotationAssertion(rdfs:label "alpha-amino acid metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (alpha-amino acid catabolic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "The chemical reactions and pathways resulting in the breakdown of an alpha-amino acid.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2012-11-08T17:39:54Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "alpha-amino acid breakdown") -AnnotationAssertion(Annotation( "GOC:TermGenie") "alpha-amino acid catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "alpha-amino acid degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901606") -AnnotationAssertion(rdfs:label "alpha-amino acid catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (alpha-amino acid biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "The chemical reactions and pathways resulting in the formation of an alpha-amino acid.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2012-11-08T17:39:58Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "alpha-amino acid anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "alpha-amino acid biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "alpha-amino acid formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "alpha-amino acid synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901607") -AnnotationAssertion(rdfs:label "alpha-amino acid biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of vesicle transport along microtubule) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that modulates the frequency, rate or extent of vesicle transport along microtubule.") -AnnotationAssertion( "hjd") -AnnotationAssertion( "2012-11-08T21:49:44Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of microtubule-based vesicle localization") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901608") -AnnotationAssertion(rdfs:label "regulation of vesicle transport along microtubule") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of vesicle transport along microtubule) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that stops, prevents or reduces the frequency, rate or extent of vesicle transport along microtubule.") -AnnotationAssertion( "hjd") -AnnotationAssertion( "2012-11-08T21:49:48Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of microtubule-based vesicle localization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of vesicle transport along microtubule") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of microtubule-based vesicle localization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of vesicle transport along microtubule") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of microtubule-based vesicle localization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of vesicle transport along microtubule") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of microtubule-based vesicle localization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of microtubule-based vesicle localization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of vesicle transport along microtubule") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901609") -AnnotationAssertion(rdfs:label "negative regulation of vesicle transport along microtubule") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of vesicle transport along microtubule) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that activates or increases the frequency, rate or extent of vesicle transport along microtubule.") -AnnotationAssertion( "hjd") -AnnotationAssertion( "2012-11-08T21:49:53Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of microtubule-based vesicle localization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of microtubule-based vesicle localization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of microtubule-based vesicle localization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of vesicle transport along microtubule") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of microtubule-based vesicle localization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of vesicle transport along microtubule") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of microtubule-based vesicle localization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of vesicle transport along microtubule") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of vesicle transport along microtubule") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901610") -AnnotationAssertion(rdfs:label "positive regulation of vesicle transport along microtubule") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (organic hydroxy compound metabolic process) AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:pr") "The chemical reactions and pathways involving organic hydroxy compound.") @@ -119455,22 +28055,8 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:1901615") AnnotationAssertion(rdfs:label "organic hydroxy compound metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (organic hydroxy compound catabolic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:pr") "The chemical reactions and pathways resulting in the breakdown of organic hydroxy compound.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2012-11-13T12:54:31Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "organic hydroxy compound breakdown") -AnnotationAssertion(Annotation( "GOC:TermGenie") "organic hydroxy compound catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "organic hydroxy compound degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901616") -AnnotationAssertion(rdfs:label "organic hydroxy compound catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (organic hydroxy compound biosynthetic process) AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:pr") "The chemical reactions and pathways resulting in the formation of organic hydroxy compound.") @@ -119483,1171 +28069,9 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:1901617") AnnotationAssertion(rdfs:label "organic hydroxy compound biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) -# Class: (organic hydroxy compound transmembrane transporter activity) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:pr") "Enables the transfer of organic hydroxy compound from one side of a membrane to the other.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2012-11-13T12:59:01Z") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:1901618") -AnnotationAssertion(rdfs:label "organic hydroxy compound transmembrane transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of lymphocyte chemotaxis) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that modulates the frequency, rate or extent of lymphocyte chemotaxis.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2012-11-13T23:03:23Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901623") -AnnotationAssertion(rdfs:label "regulation of lymphocyte chemotaxis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of lymphocyte chemotaxis) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that stops, prevents or reduces the frequency, rate or extent of lymphocyte chemotaxis.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2012-11-13T23:03:28Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of lymphocyte chemotaxis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of lymphocyte chemotaxis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of lymphocyte chemotaxis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of lymphocyte chemotaxis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901624") -AnnotationAssertion(rdfs:label "negative regulation of lymphocyte chemotaxis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of postsynaptic membrane organization) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "PMID:22426000") "Any process that modulates the frequency, rate or extent of postsynaptic membrane organization.") -AnnotationAssertion( "ans") -AnnotationAssertion( "2012-11-15T11:40:15Z") -AnnotationAssertion( "regulation of post-synaptic membrane organization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of postsynaptic membrane organisation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901626") -AnnotationAssertion(rdfs:label "regulation of postsynaptic membrane organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of postsynaptic membrane organization) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "PMID:22426000") "Any process that stops, prevents or reduces the frequency, rate or extent of postsynaptic membrane organization.") -AnnotationAssertion( "ans") -AnnotationAssertion( "2012-11-15T11:40:20Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of postsynaptic membrane organisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of postsynaptic membrane organization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of postsynaptic membrane organisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of postsynaptic membrane organization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of postsynaptic membrane organisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of postsynaptic membrane organization") -AnnotationAssertion( "negative regulation of post-synaptic membrane organization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of postsynaptic membrane organisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of postsynaptic membrane organisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of postsynaptic membrane organization") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901627") -AnnotationAssertion(rdfs:label "negative regulation of postsynaptic membrane organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of postsynaptic membrane organization) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "PMID:22426000") "Any process that activates or increases the frequency, rate or extent of postsynaptic membrane organization.") -AnnotationAssertion( "ans") -AnnotationAssertion( "2012-11-15T11:40:24Z") -AnnotationAssertion( "positive regulation of post-synaptic membrane organization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of postsynaptic membrane organisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of postsynaptic membrane organisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of postsynaptic membrane organization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of postsynaptic membrane organisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of postsynaptic membrane organization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of postsynaptic membrane organisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of postsynaptic membrane organization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of postsynaptic membrane organisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of postsynaptic membrane organization") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901628") -AnnotationAssertion(rdfs:label "positive regulation of postsynaptic membrane organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (nucleoside transmembrane transport) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:pr") "The directed movement of nucleoside across a membrane.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2012-11-16T13:32:01Z") -AnnotationAssertion( "nucleoside membrane transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901642") -AnnotationAssertion(rdfs:comment "Note that this term is not intended for use in annotating lateral movement within membranes.") -AnnotationAssertion(rdfs:label "nucleoside transmembrane transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (regulation of synoviocyte proliferation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that modulates the frequency, rate or extent of synoviocyte proliferation.") -AnnotationAssertion( "hjd") -AnnotationAssertion( "2012-11-16T20:16:23Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901645") -AnnotationAssertion(rdfs:label "regulation of synoviocyte proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of synoviocyte proliferation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that stops, prevents or reduces the frequency, rate or extent of synoviocyte proliferation.") -AnnotationAssertion( "hjd") -AnnotationAssertion( "2012-11-16T20:16:27Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of synoviocyte proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of synoviocyte proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of synoviocyte proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of synoviocyte proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901646") -AnnotationAssertion(rdfs:label "negative regulation of synoviocyte proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of synoviocyte proliferation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that activates or increases the frequency, rate or extent of synoviocyte proliferation.") -AnnotationAssertion( "hjd") -AnnotationAssertion( "2012-11-16T20:16:32Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of synoviocyte proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of synoviocyte proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of synoviocyte proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of synoviocyte proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901647") -AnnotationAssertion(rdfs:label "positive regulation of synoviocyte proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (response to peptide) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:pr") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide stimulus.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2012-11-20T09:45:15Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901652") -AnnotationAssertion(rdfs:label "response to peptide") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cellular response to peptide) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:pr") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide stimulus.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2012-11-20T09:45:19Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901653") -AnnotationAssertion(rdfs:label "cellular response to peptide") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (response to ketone) - -AnnotationAssertion(Annotation( "GOC:mengo_curators") Annotation( "PMID:23356676") "A response that results in a state of tolerance to ketone.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2012-11-20T10:55:47Z") -AnnotationAssertion( "GO:1990369") -AnnotationAssertion( "process resulting in tolerance to ketone") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901654") -AnnotationAssertion(rdfs:label "response to ketone") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (cellular response to ketone) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:pr") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ketone stimulus.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2012-11-20T10:55:51Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901655") -AnnotationAssertion(rdfs:label "cellular response to ketone") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (glycosyl compound metabolic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:pr") "The chemical reactions and pathways involving glycosyl compound.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2012-11-20T14:24:07Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "glycosyl compound metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901657") -AnnotationAssertion(rdfs:label "glycosyl compound metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (glycosyl compound catabolic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:pr") "The chemical reactions and pathways resulting in the breakdown of glycosyl compound.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2012-11-20T14:24:11Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "glycosyl compound breakdown") -AnnotationAssertion(Annotation( "GOC:TermGenie") "glycosyl compound catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "glycosyl compound degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901658") -AnnotationAssertion(rdfs:label "glycosyl compound catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (glycosyl compound biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:pr") "The chemical reactions and pathways resulting in the formation of glycosyl compound.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2012-11-20T14:24:19Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "glycosyl compound anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "glycosyl compound biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "glycosyl compound formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "glycosyl compound synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901659") -AnnotationAssertion(rdfs:label "glycosyl compound biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (nucleotide transmembrane transport) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:pr") "The directed movement of nucleotide across a membrane.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2012-11-22T15:43:23Z") -AnnotationAssertion( "nucleotide membrane transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901679") -AnnotationAssertion(rdfs:comment "Note that this term is not intended for use in annotating lateral movement within membranes.") -AnnotationAssertion(rdfs:label "nucleotide transmembrane transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (sulfur compound binding) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:pr") "Binding to a sulfur compound.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2012-11-26T20:45:23Z") -AnnotationAssertion( "sulfur molecular entity binding") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:1901681") -AnnotationAssertion(rdfs:label "sulfur compound binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (sulfur compound transmembrane transporter activity) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:pr") "Enables the transfer of a sulfur compound from one side of a membrane to the other.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2012-11-26T20:45:29Z") -AnnotationAssertion( "sulfur molecular entity transmembrane transporter activity") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:1901682") -AnnotationAssertion(rdfs:label "sulfur compound transmembrane transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of compound eye retinal cell apoptotic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mtg_apoptosis") Annotation( "PMID:12021768") "Any process that modulates the frequency, rate or extent of compound eye retinal cell apoptotic process.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2012-12-12T10:28:35Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901692") -AnnotationAssertion(rdfs:label "regulation of compound eye retinal cell apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of compound eye retinal cell apoptotic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mtg_apoptosis") Annotation( "PMID:12021768") "Any process that stops, prevents or reduces the frequency, rate or extent of compound eye retinal cell apoptotic process.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2012-12-12T10:28:40Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of compound eye retinal cell apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of compound eye retinal cell apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of compound eye retinal cell apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of compound eye retinal cell apoptotic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901693") -AnnotationAssertion(rdfs:label "negative regulation of compound eye retinal cell apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of compound eye retinal cell apoptotic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mtg_apoptosis") Annotation( "PMID:12021768") "Any process that activates or increases the frequency, rate or extent of compound eye retinal cell apoptotic process.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2012-12-12T10:28:45Z") -AnnotationAssertion( "GO:0046675") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of compound eye retinal cell apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of compound eye retinal cell apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of compound eye retinal cell apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of compound eye retinal cell apoptotic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "induction of compound eye retinal cell programmed cell death") -AnnotationAssertion( "GO:1901694") -AnnotationAssertion(rdfs:label "positive regulation of compound eye retinal cell apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (response to nitrogen compound) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:pr") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen compound stimulus.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2012-12-13T15:06:08Z") -AnnotationAssertion( "response to nitrogen molecular entity") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901698") -AnnotationAssertion(rdfs:label "response to nitrogen compound") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cellular response to nitrogen compound) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:pr") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen compound stimulus.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2012-12-13T15:06:13Z") -AnnotationAssertion( "cellular response to nitrogen molecular entity") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901699") -AnnotationAssertion(rdfs:label "cellular response to nitrogen compound") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (response to oxygen-containing compound) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:pr") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen-containing compound stimulus.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2012-12-13T15:11:37Z") -AnnotationAssertion( "response to oxygen molecular entity") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901700") -AnnotationAssertion(rdfs:label "response to oxygen-containing compound") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (cellular response to oxygen-containing compound) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:pr") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen-containing compound stimulus.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2012-12-13T15:11:42Z") -AnnotationAssertion( "cellular response to oxygen molecular entity") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901701") -AnnotationAssertion(rdfs:label "cellular response to oxygen-containing compound") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (salt transmembrane transporter activity) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:pr") "Enables the transfer of salt from one side of a membrane to the other.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2012-12-13T15:14:47Z") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:1901702") -AnnotationAssertion(rdfs:label "salt transmembrane transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (mesenchymal cell differentiation involved in bone development) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:hjd") Annotation( "PMID:21571217") "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of bone as it progresses from its formation to the mature state.") -AnnotationAssertion( "hjd") -AnnotationAssertion( "2012-12-14T16:04:16Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901706") -AnnotationAssertion(rdfs:label "mesenchymal cell differentiation involved in bone development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of gamma-aminobutyric acid catabolic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that modulates the frequency, rate or extent of gamma-aminobutyric acid catabolic process.") -AnnotationAssertion( "mcc") -AnnotationAssertion( "2012-12-19T16:13:24Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of 4-aminobutanoate catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of 4-aminobutanoate catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of 4-aminobutyrate catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of 4-aminobutyrate catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of GABA catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of GABA catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of gamma-aminobutyric acid breakdown") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of gamma-aminobutyric acid catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of gamma-aminobutyric acid degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901715") -AnnotationAssertion(rdfs:label "regulation of gamma-aminobutyric acid catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of gamma-aminobutyric acid catabolic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that stops, prevents or reduces the frequency, rate or extent of gamma-aminobutyric acid catabolic process.") -AnnotationAssertion( "mcc") -AnnotationAssertion( "2012-12-19T16:13:31Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of 4-aminobutanoate catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of 4-aminobutanoate catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of 4-aminobutyrate catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of 4-aminobutyrate catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of GABA catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of GABA catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of gamma-aminobutyric acid breakdown") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of gamma-aminobutyric acid catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of gamma-aminobutyric acid catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of gamma-aminobutyric acid degradation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of 4-aminobutanoate catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of 4-aminobutanoate catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of 4-aminobutyrate catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of 4-aminobutyrate catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of GABA catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of GABA catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of gamma-aminobutyric acid breakdown") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of gamma-aminobutyric acid catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of gamma-aminobutyric acid catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of gamma-aminobutyric acid degradation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of 4-aminobutanoate catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of 4-aminobutanoate catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of 4-aminobutyrate catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of 4-aminobutyrate catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of GABA catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of GABA catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of gamma-aminobutyric acid breakdown") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of gamma-aminobutyric acid catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of gamma-aminobutyric acid catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of gamma-aminobutyric acid degradation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of 4-aminobutanoate catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of 4-aminobutanoate catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of 4-aminobutyrate catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of 4-aminobutyrate catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of GABA catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of GABA catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of gamma-aminobutyric acid breakdown") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of gamma-aminobutyric acid catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of gamma-aminobutyric acid degradation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of 4-aminobutanoate catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of 4-aminobutanoate catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of 4-aminobutyrate catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of 4-aminobutyrate catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of GABA catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of GABA catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of gamma-aminobutyric acid breakdown") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of gamma-aminobutyric acid catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of gamma-aminobutyric acid degradation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of gamma-aminobutyric acid catabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901716") -AnnotationAssertion(rdfs:label "negative regulation of gamma-aminobutyric acid catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of gamma-aminobutyric acid catabolic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that activates or increases the frequency, rate or extent of gamma-aminobutyric acid catabolic process.") -AnnotationAssertion( "mcc") -AnnotationAssertion( "2012-12-19T16:13:36Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of 4-aminobutanoate catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of 4-aminobutanoate catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of 4-aminobutyrate catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of 4-aminobutyrate catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of GABA catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of GABA catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of gamma-aminobutyric acid breakdown") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of gamma-aminobutyric acid catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of gamma-aminobutyric acid degradation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of 4-aminobutanoate catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of 4-aminobutanoate catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of 4-aminobutyrate catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of 4-aminobutyrate catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of GABA catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of GABA catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of gamma-aminobutyric acid breakdown") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of gamma-aminobutyric acid catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of gamma-aminobutyric acid degradation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of 4-aminobutanoate catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of 4-aminobutanoate catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of 4-aminobutyrate catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of 4-aminobutyrate catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of GABA catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of GABA catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of gamma-aminobutyric acid breakdown") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of gamma-aminobutyric acid catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of gamma-aminobutyric acid catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of gamma-aminobutyric acid degradation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of 4-aminobutanoate catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of 4-aminobutanoate catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of 4-aminobutyrate catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of 4-aminobutyrate catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of GABA catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of GABA catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of gamma-aminobutyric acid breakdown") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of gamma-aminobutyric acid catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of gamma-aminobutyric acid catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of gamma-aminobutyric acid degradation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of 4-aminobutanoate catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of 4-aminobutanoate catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of 4-aminobutyrate catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of 4-aminobutyrate catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of GABA catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of GABA catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of gamma-aminobutyric acid breakdown") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of gamma-aminobutyric acid catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of gamma-aminobutyric acid catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of gamma-aminobutyric acid degradation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of gamma-aminobutyric acid catabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901717") -AnnotationAssertion(rdfs:label "positive regulation of gamma-aminobutyric acid catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of cell proliferation involved in kidney development) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "PMID:18182616") "Any process that modulates the frequency, rate or extent of cell proliferation involved in kidney development.") -AnnotationAssertion( "krc") -AnnotationAssertion( "2012-12-27T19:30:31Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901722") -AnnotationAssertion(rdfs:label "regulation of cell proliferation involved in kidney development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of cell proliferation involved in kidney development) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "PMID:18182616") "Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation involved in kidney development.") -AnnotationAssertion( "krc") -AnnotationAssertion( "2012-12-27T19:30:35Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of cell proliferation involved in kidney development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of cell proliferation involved in kidney development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of cell proliferation involved in kidney development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of cell proliferation involved in kidney development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901723") -AnnotationAssertion(rdfs:label "negative regulation of cell proliferation involved in kidney development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of cell proliferation involved in kidney development) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "PMID:18182616") "Any process that activates or increases the frequency, rate or extent of cell proliferation involved in kidney development.") -AnnotationAssertion( "krc") -AnnotationAssertion( "2012-12-27T19:30:40Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of cell proliferation involved in kidney development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of cell proliferation involved in kidney development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of cell proliferation involved in kidney development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of cell proliferation involved in kidney development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901724") -AnnotationAssertion(rdfs:label "positive regulation of cell proliferation involved in kidney development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (beta-carotene metabolic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:yaf") Annotation( "MetaCyc:PWY-5943") Annotation( "PMID:11387982") Annotation( "UniPathway:UPA00802") "The chemical reactions and pathways involving beta-carotene.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2013-01-22T10:30:23Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "beta-carotene metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901810") -AnnotationAssertion(rdfs:label "beta-carotene metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (beta-carotene catabolic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:yaf") Annotation( "MetaCyc:PWY-5943") Annotation( "PMID:11387982") Annotation( "UniPathway:UPA00802") "The chemical reactions and pathways resulting in the breakdown of beta-carotene.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2013-01-22T10:30:28Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "beta-carotene breakdown") -AnnotationAssertion(Annotation( "GOC:TermGenie") "beta-carotene catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "beta-carotene degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901811") -AnnotationAssertion(rdfs:label "beta-carotene catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (beta-carotene biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:yaf") Annotation( "MetaCyc:PWY-5943") Annotation( "PMID:11387982") Annotation( "UniPathway:UPA00802") "The chemical reactions and pathways resulting in the formation of beta-carotene.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2013-01-22T10:30:32Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "beta-carotene anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "beta-carotene biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "beta-carotene formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "beta-carotene synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901812") -AnnotationAssertion(rdfs:label "beta-carotene biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (zeaxanthin metabolic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:yaf") Annotation( "MetaCyc:PWY-5944") Annotation( "UniPathway:UPA00843") "The chemical reactions and pathways involving zeaxanthin.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2013-01-22T11:36:55Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "zeaxanthin metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901825") -AnnotationAssertion(rdfs:label "zeaxanthin metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (zeaxanthin catabolic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:yaf") Annotation( "MetaCyc:PWY-5944") Annotation( "UniPathway:UPA00843") "The chemical reactions and pathways resulting in the breakdown of zeaxanthin.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2013-01-22T11:37:00Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "zeaxanthin breakdown") -AnnotationAssertion(Annotation( "GOC:TermGenie") "zeaxanthin catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "zeaxanthin degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901826") -AnnotationAssertion(rdfs:label "zeaxanthin catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (zeaxanthin biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:yaf") Annotation( "MetaCyc:PWY-5944") Annotation( "UniPathway:UPA00843") "The chemical reactions and pathways resulting in the formation of zeaxanthin.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2013-01-22T11:37:07Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "zeaxanthin anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "zeaxanthin biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "zeaxanthin formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "zeaxanthin synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901827") -AnnotationAssertion(rdfs:label "zeaxanthin biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of muscle tissue development) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:yaf") Annotation( "PMID:23150719") "Any process that modulates the frequency, rate or extent of muscle tissue development.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2013-02-01T10:30:47Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901861") -AnnotationAssertion(rdfs:label "regulation of muscle tissue development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of muscle tissue development) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:yaf") Annotation( "PMID:23150719") "Any process that stops, prevents or reduces the frequency, rate or extent of muscle tissue development.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2013-02-01T10:30:52Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of muscle tissue development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of muscle tissue development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of muscle tissue development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of muscle tissue development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901862") -AnnotationAssertion(rdfs:label "negative regulation of muscle tissue development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of muscle tissue development) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:yaf") Annotation( "PMID:23150719") "Any process that activates or increases the frequency, rate or extent of muscle tissue development.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2013-02-01T10:30:57Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of muscle tissue development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of muscle tissue development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of muscle tissue development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of muscle tissue development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901863") -AnnotationAssertion(rdfs:label "positive regulation of muscle tissue development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of calcium ion binding) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "PMID:16432188") "Any process that modulates the frequency, rate or extent of calcium ion binding.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2013-02-06T12:38:12Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of calcium ion storage activity") -AnnotationAssertion( "GO:1901876") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "regulation of calcium ion binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of calcium ion binding) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "PMID:16432188") "Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion binding.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2013-02-06T12:38:22Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of calcium ion binding") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of calcium ion binding") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of calcium ion binding") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of calcium ion binding") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of calcium ion storage activity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of calcium ion storage activity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of calcium ion storage activity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of calcium ion storage activity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of calcium ion storage activity") -AnnotationAssertion( "GO:1901877") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "negative regulation of calcium ion binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of calcium ion binding) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "PMID:16432188") "Any process that activates or increases the frequency, rate or extent of calcium ion binding.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2013-02-06T12:38:26Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of calcium ion binding") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of calcium ion binding") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of calcium ion binding") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of calcium ion binding") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of calcium ion storage activity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of calcium ion storage activity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of calcium ion storage activity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of calcium ion storage activity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of calcium ion storage activity") -AnnotationAssertion( "GO:1901878") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "positive regulation of calcium ion binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of protein depolymerization) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "PMID:12032137") "Any process that modulates the frequency, rate or extent of protein depolymerization.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2013-02-06T13:57:23Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of protein polymer breakdown") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of protein polymer catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of protein polymer catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of protein polymer degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901879") -AnnotationAssertion(rdfs:label "regulation of protein depolymerization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of protein depolymerization) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "PMID:12032137") "Any process that stops, prevents or reduces the frequency, rate or extent of protein depolymerization.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2013-02-06T13:57:28Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of protein depolymerization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of protein polymer breakdown") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of protein polymer catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of protein polymer catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of protein polymer degradation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of protein depolymerization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of protein polymer breakdown") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of protein polymer catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of protein polymer catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of protein polymer degradation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of protein depolymerization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of protein polymer breakdown") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of protein polymer catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of protein polymer catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of protein polymer degradation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of protein polymer breakdown") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of protein polymer catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of protein polymer catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of protein polymer degradation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of protein polymer breakdown") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of protein polymer catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of protein polymer catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of protein polymer degradation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of protein depolymerization") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901880") -AnnotationAssertion(rdfs:label "negative regulation of protein depolymerization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of protein depolymerization) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "PMID:12032137") "Any process that activates or increases the frequency, rate or extent of protein depolymerization.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2013-02-06T13:57:32Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of protein polymer breakdown") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of protein polymer catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of protein polymer catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of protein polymer degradation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of protein polymer breakdown") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of protein polymer catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of protein polymer catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of protein polymer degradation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of protein depolymerization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of protein polymer breakdown") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of protein polymer catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of protein polymer catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of protein polymer degradation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of protein depolymerization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of protein polymer breakdown") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of protein polymer catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of protein polymer catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of protein polymer degradation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of protein depolymerization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of protein polymer breakdown") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of protein polymer catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of protein polymer catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of protein polymer degradation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of protein depolymerization") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901881") -AnnotationAssertion(rdfs:label "positive regulation of protein depolymerization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of cell junction assembly) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that modulates the frequency, rate or extent of cell junction assembly.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2013-02-06T19:40:32Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901888") -AnnotationAssertion(rdfs:label "regulation of cell junction assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (negative regulation of cell junction assembly) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that stops, prevents or reduces the frequency, rate or extent of cell junction assembly.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2013-02-06T19:40:41Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of cell junction assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of cell junction assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of cell junction assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of cell junction assembly") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901889") -AnnotationAssertion(rdfs:label "negative regulation of cell junction assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of cell junction assembly) - -AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that activates or increases the frequency, rate or extent of cell junction assembly.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2013-02-06T19:40:46Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of cell junction assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of cell junction assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of cell junction assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of cell junction assembly") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901890") -AnnotationAssertion(rdfs:label "positive regulation of cell junction assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (dense core granule transport) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:kmv") Annotation( "PMID:23358451") "The directed movement a dense core granule within a cell.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2013-02-19T13:00:52Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "dense core vesicle transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901950") -AnnotationAssertion(rdfs:comment "goslim_synapse") -AnnotationAssertion(rdfs:label "dense core granule transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of anterograde dense core granule transport) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:kmv") Annotation( "PMID:23358451") "Any process that modulates the frequency, rate or extent of anterograde dense core granule transport.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2013-02-19T13:36:21Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901951") -AnnotationAssertion(rdfs:label "regulation of anterograde dense core granule transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of anterograde dense core granule transport) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:kmv") Annotation( "PMID:23358451") "Any process that stops, prevents or reduces the frequency, rate or extent of anterograde dense core granule transport.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2013-02-19T13:36:30Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of anterograde dense core granule transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of anterograde dense core granule transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of anterograde dense core granule transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of anterograde dense core granule transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901952") -AnnotationAssertion(rdfs:label "negative regulation of anterograde dense core granule transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of anterograde dense core granule transport) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:kmv") Annotation( "PMID:23358451") "Any process that activates or increases the frequency, rate or extent of anterograde dense core granule transport.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2013-02-19T13:36:35Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of anterograde dense core granule transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of anterograde dense core granule transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of anterograde dense core granule transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of anterograde dense core granule transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901953") -AnnotationAssertion(rdfs:label "positive regulation of anterograde dense core granule transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of retrograde dense core granule transport) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:kmv") Annotation( "PMID:23358451") "Any process that modulates the frequency, rate or extent of retrograde dense core granule transport.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2013-02-19T13:36:43Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901954") -AnnotationAssertion(rdfs:label "regulation of retrograde dense core granule transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of retrograde dense core granule transport) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:kmv") Annotation( "PMID:23358451") "Any process that stops, prevents or reduces the frequency, rate or extent of retrograde dense core granule transport.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2013-02-19T13:36:47Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of retrograde dense core granule transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of retrograde dense core granule transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of retrograde dense core granule transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of retrograde dense core granule transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901955") -AnnotationAssertion(rdfs:label "negative regulation of retrograde dense core granule transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of retrograde dense core granule transport) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:kmv") Annotation( "PMID:23358451") "Any process that activates or increases the frequency, rate or extent of retrograde dense core granule transport.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2013-02-19T13:36:52Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of retrograde dense core granule transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of retrograde dense core granule transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of retrograde dense core granule transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of retrograde dense core granule transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901956") -AnnotationAssertion(rdfs:label "positive regulation of retrograde dense core granule transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of cell proliferation involved in outflow tract morphogenesis) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:dph") Annotation( "GOC:mtg_heart") Annotation( "PMID:21419760") "Any process that modulates the frequency, rate or extent of cell proliferation involved in outflow tract morphogenesis.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2013-02-20T20:30:26Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901963") -AnnotationAssertion(rdfs:label "regulation of cell proliferation involved in outflow tract morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of cell proliferation involved in outflow tract morphogenesis) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:dph") Annotation( "GOC:mtg_heart") Annotation( "PMID:21419760") "Any process that activates or increases the frequency, rate or extent of cell proliferation involved in outflow tract morphogenesis.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2013-02-20T20:30:31Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of cell proliferation involved in outflow tract morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of cell proliferation involved in outflow tract morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of cell proliferation involved in outflow tract morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of cell proliferation involved in outflow tract morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1901964") -AnnotationAssertion(rdfs:label "positive regulation of cell proliferation involved in outflow tract morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (fatty acid transmembrane transport) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:rb") Annotation( "PMID:9395310") "The process in which a fatty acid is transported across a membrane.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2013-03-21T09:57:00Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902001") -AnnotationAssertion(rdfs:label "fatty acid transmembrane transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (regulation of cilium assembly) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:cilia") Annotation( "GOC:dph") Annotation( "PMID:17719545") "Any process that modulates the frequency, rate or extent of cilium assembly.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2013-03-26T18:10:51Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of ciliogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of cilium biogenesis") -AnnotationAssertion( "GO:1902017") -AnnotationAssertion(rdfs:label "regulation of cilium assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of cilium assembly) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:cilia") Annotation( "GOC:dph") Annotation( "PMID:17719545") "Any process that stops, prevents or reduces the frequency, rate or extent of cilium assembly.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2013-03-26T18:10:56Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of ciliogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of cilium assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of ciliogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of cilium assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of ciliogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of cilium assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of ciliogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of ciliogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of cilium assembly") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of cilium biogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of cilium biogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of cilium biogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of cilium biogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of cilium biogenesis") -AnnotationAssertion( "GO:1902018") -AnnotationAssertion(rdfs:label "negative regulation of cilium assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of cilium-dependent cell motility) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:cilia") Annotation( "GOC:jl") "Any process that modulates the frequency, rate or extent of cilium-dependent cell motility.") -AnnotationAssertion( "jl") -AnnotationAssertion( "2013-03-27T14:42:38Z") -AnnotationAssertion( "regulation of cilium cell motility") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "regulation of ciliary cell motility") -AnnotationAssertion( "GO:1902019") -AnnotationAssertion(rdfs:label "regulation of cilium-dependent cell motility") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of cilium-dependent cell motility) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:cilia") Annotation( "GOC:jl") "Any process that stops, prevents or reduces the frequency, rate or extent of cilium-dependent cell motility.") -AnnotationAssertion( "jl") -AnnotationAssertion( "2013-03-27T14:42:42Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of ciliary cell motility") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of ciliary cell motility") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of ciliary cell motility") -AnnotationAssertion( "negative regulation of cilium cell motility") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of ciliary cell motility") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "negative regulation of ciliary cell motility") -AnnotationAssertion( "GO:1902020") -AnnotationAssertion(rdfs:label "negative regulation of cilium-dependent cell motility") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of hematopoietic stem cell proliferation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "PMID:23403623") "Any process that modulates the frequency, rate or extent of hematopoietic stem cell proliferation.") -AnnotationAssertion( "ss") -AnnotationAssertion( "2013-04-02T05:13:19Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of hemopoietic stem cell proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902033") -AnnotationAssertion(rdfs:label "regulation of hematopoietic stem cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of hematopoietic stem cell proliferation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "PMID:23403623") "Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic stem cell proliferation.") -AnnotationAssertion( "ss") -AnnotationAssertion( "2013-04-02T05:13:24Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of hematopoietic stem cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of hemopoietic stem cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of hematopoietic stem cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of hemopoietic stem cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of hematopoietic stem cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of hemopoietic stem cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of hemopoietic stem cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of hematopoietic stem cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of hemopoietic stem cell proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902034") -AnnotationAssertion(rdfs:label "negative regulation of hematopoietic stem cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of hematopoietic stem cell proliferation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "PMID:23403623") "Any process that activates or increases the frequency, rate or extent of hematopoietic stem cell proliferation.") -AnnotationAssertion( "ss") -AnnotationAssertion( "2013-04-02T05:13:31Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of hemopoietic stem cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of hematopoietic stem cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of hemopoietic stem cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of hematopoietic stem cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of hemopoietic stem cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of hematopoietic stem cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of hemopoietic stem cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of hematopoietic stem cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of hemopoietic stem cell proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902035") -AnnotationAssertion(rdfs:label "positive regulation of hematopoietic stem cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of hematopoietic stem cell differentiation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "PMID:23403623") "Any process that modulates the frequency, rate or extent of hematopoietic stem cell differentiation.") -AnnotationAssertion( "ss") -AnnotationAssertion( "2013-04-02T05:19:09Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of haematopoietic stem cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of haemopoietic stem cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of hemopoietic stem cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902036") -AnnotationAssertion(rdfs:label "regulation of hematopoietic stem cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of hematopoietic stem cell differentiation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "PMID:23403623") "Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic stem cell differentiation.") -AnnotationAssertion( "ss") -AnnotationAssertion( "2013-04-02T05:19:14Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of haematopoietic stem cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of haemopoietic stem cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of hematopoietic stem cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of hemopoietic stem cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of haematopoietic stem cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of haemopoietic stem cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of hematopoietic stem cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of hemopoietic stem cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of haematopoietic stem cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of haemopoietic stem cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of hematopoietic stem cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of hemopoietic stem cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of haematopoietic stem cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of haemopoietic stem cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of hemopoietic stem cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of haematopoietic stem cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of haemopoietic stem cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of hematopoietic stem cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of hemopoietic stem cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902037") -AnnotationAssertion(rdfs:label "negative regulation of hematopoietic stem cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of hematopoietic stem cell differentiation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "PMID:23403623") "Any process that activates or increases the frequency, rate or extent of hematopoietic stem cell differentiation.") -AnnotationAssertion( "ss") -AnnotationAssertion( "2013-04-02T05:19:19Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of haematopoietic stem cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of haemopoietic stem cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of hemopoietic stem cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of haematopoietic stem cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of haemopoietic stem cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of hematopoietic stem cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of hemopoietic stem cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of haematopoietic stem cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of haemopoietic stem cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of hematopoietic stem cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of hemopoietic stem cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of haematopoietic stem cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of haemopoietic stem cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of hematopoietic stem cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of hemopoietic stem cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of haematopoietic stem cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of haemopoietic stem cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of hematopoietic stem cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of hemopoietic stem cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902038") -AnnotationAssertion(rdfs:label "positive regulation of hematopoietic stem cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (response to L-glutamate) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "PMID:23574009") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an L-glutamate stimulus.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2013-04-16T21:21:14Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902065") -AnnotationAssertion(rdfs:label "response to L-glutamate") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (response to salt) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mls") Annotation( "PMID:16666921") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a salt stimulus.") -AnnotationAssertion( "mls") -AnnotationAssertion( "2013-04-22T15:41:57Z") -AnnotationAssertion(Annotation( "GOC:mls") "response to salinity") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902074") -AnnotationAssertion(rdfs:label "response to salt") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cellular response to salt) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mls") Annotation( "PMID:16666921") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a salt stimulus.") -AnnotationAssertion( "mls") -AnnotationAssertion( "2013-04-22T15:42:02Z") -AnnotationAssertion(Annotation( "GOC:mls") "cellular response to salinity") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902075") -AnnotationAssertion(rdfs:label "cellular response to salt") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (positive regulation of flagellated sperm motility) AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:cilia") Annotation( "GOC:jh2") Annotation( "GOC:krc") Annotation( "PMID:7513657") "Any process that activates or increases the frequency, rate or extent of flagellated sperm motility.") @@ -120666,3915 +28090,9 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:1902093") AnnotationAssertion(rdfs:label "positive regulation of flagellated sperm motility") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) -# Class: (regulation of leukocyte differentiation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:add") "Any process that modulates the frequency, rate or extent of leukocyte differentiation.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2013-05-02T17:32:42Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of immune cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of leucocyte differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902105") -AnnotationAssertion(rdfs:label "regulation of leukocyte differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of leukocyte differentiation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:add") "Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte differentiation.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2013-05-02T17:32:47Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of immune cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of leucocyte differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of leukocyte differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of immune cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of leucocyte differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of leukocyte differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of immune cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of leucocyte differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of leukocyte differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of immune cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of leucocyte differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of immune cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of leucocyte differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of leukocyte differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902106") -AnnotationAssertion(rdfs:label "negative regulation of leukocyte differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of leukocyte differentiation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:add") "Any process that activates or increases the frequency, rate or extent of leukocyte differentiation.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2013-05-02T17:32:52Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of immune cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of leucocyte differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of immune cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of leucocyte differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of leukocyte differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of immune cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of leucocyte differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of leukocyte differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of immune cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of leucocyte differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of leukocyte differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of immune cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of leucocyte differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of leukocyte differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902107") -AnnotationAssertion(rdfs:label "positive regulation of leukocyte differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of organelle assembly) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:pr") "Any process that modulates the frequency, rate or extent of organelle assembly.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2013-05-14T09:43:21Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902115") -AnnotationAssertion(rdfs:label "regulation of organelle assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (negative regulation of organelle assembly) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:pr") "Any process that stops, prevents or reduces the frequency, rate or extent of organelle assembly.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2013-05-14T09:43:31Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of organelle assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of organelle assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of organelle assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of organelle assembly") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902116") -AnnotationAssertion(rdfs:label "negative regulation of organelle assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of organelle assembly) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:pr") "Any process that activates or increases the frequency, rate or extent of organelle assembly.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2013-05-14T09:43:36Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of organelle assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of organelle assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of organelle assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of organelle assembly") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902117") -AnnotationAssertion(rdfs:label "positive regulation of organelle assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (regulation of keratinocyte apoptotic process) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:rl") Annotation( "PMID:18938133") "Any process that modulates the frequency, rate or extent of keratinocyte apoptotic process.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2013-05-29T14:36:11Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of keratinocyte apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902172") -AnnotationAssertion(rdfs:label "regulation of keratinocyte apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of keratinocyte apoptotic process) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:rl") Annotation( "PMID:18938133") "Any process that stops, prevents or reduces the frequency, rate or extent of keratinocyte apoptotic process.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2013-05-29T14:36:15Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of keratinocyte apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of keratinocyte apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of keratinocyte apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of keratinocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of keratinocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of keratinocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of keratinocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of keratinocyte apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of keratinocyte apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902173") -AnnotationAssertion(rdfs:label "negative regulation of keratinocyte apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of keratinocyte apoptotic process) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:rl") Annotation( "PMID:18938133") "Any process that activates or increases the frequency, rate or extent of keratinocyte apoptotic process.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2013-05-29T14:36:21Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of keratinocyte apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of keratinocyte apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of keratinocyte apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of keratinocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of keratinocyte apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of keratinocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of keratinocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of keratinocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of keratinocyte apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902174") -AnnotationAssertion(rdfs:label "positive regulation of keratinocyte apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of prolactin signaling pathway) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "PMID:11773439") "Any process that modulates the frequency, rate or extent of prolactin signaling pathway.") -AnnotationAssertion( "lb") -AnnotationAssertion( "2013-06-12T10:10:07Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of PRL signaling pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of prolactin-mediated signaling pathway") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902211") -AnnotationAssertion(rdfs:label "regulation of prolactin signaling pathway") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of prolactin signaling pathway) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "PMID:11773439") "Any process that stops, prevents or reduces the frequency, rate or extent of prolactin signaling pathway.") -AnnotationAssertion( "lb") -AnnotationAssertion( "2013-06-12T10:10:12Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of PRL signaling pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of prolactin signaling pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of prolactin-mediated signaling pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of PRL signaling pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of prolactin signaling pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of prolactin-mediated signaling pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of PRL signaling pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of prolactin signaling pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of prolactin-mediated signaling pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of PRL signaling pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of prolactin-mediated signaling pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of PRL signaling pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of prolactin signaling pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of prolactin-mediated signaling pathway") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902212") -AnnotationAssertion(rdfs:label "negative regulation of prolactin signaling pathway") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of prolactin signaling pathway) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "PMID:11773439") "Any process that activates or increases the frequency, rate or extent of prolactin signaling pathway.") -AnnotationAssertion( "lb") -AnnotationAssertion( "2013-06-12T10:10:18Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of PRL signaling pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of prolactin-mediated signaling pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of PRL signaling pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of prolactin signaling pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of prolactin-mediated signaling pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of PRL signaling pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of prolactin signaling pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of prolactin-mediated signaling pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of PRL signaling pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of prolactin signaling pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of prolactin-mediated signaling pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of PRL signaling pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of prolactin signaling pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of prolactin-mediated signaling pathway") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902213") -AnnotationAssertion(rdfs:label "positive regulation of prolactin signaling pathway") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (erythrocyte apoptotic process) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:rl") Annotation( "PMID:14569084") "Any apoptotic process in an erythrocyte.") -AnnotationAssertion( ) -AnnotationAssertion( "rl") -AnnotationAssertion( "2013-06-13T10:02:29Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "RBC apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "red blood cell apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "RBC apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "erythrocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "red blood cell apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902217") -AnnotationAssertion(rdfs:label "erythrocyte apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) -DisjointClasses( ObjectSomeValuesFrom( )) - -# Class: (regulation of erythrocyte apoptotic process) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:rl") Annotation( "PMID:14569084") "Any process that modulates the frequency, rate or extent of erythrocyte apoptotic process.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2013-06-20T19:30:53Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of RBC apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of red blood cell apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of RBC apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of erythrocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of red blood cell apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902250") -AnnotationAssertion(rdfs:label "regulation of erythrocyte apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of erythrocyte apoptotic process) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:rl") Annotation( "PMID:14569084") "Any process that stops, prevents or reduces the frequency, rate or extent of erythrocyte apoptotic process.") -AnnotationAssertion( ) -AnnotationAssertion( "rl") -AnnotationAssertion( "2013-06-20T19:30:59Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of RBC apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of erythrocyte apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of red blood cell apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of RBC apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of erythrocyte apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of red blood cell apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of RBC apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of erythrocyte apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of red blood cell apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of RBC apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of red blood cell apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of RBC apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of erythrocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of red blood cell apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of RBC apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of erythrocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of red blood cell apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of RBC apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of erythrocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of red blood cell apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of RBC apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of RBC apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of erythrocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of erythrocyte apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of red blood cell apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of red blood cell apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of RBC apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of erythrocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of red blood cell apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902251") -AnnotationAssertion(rdfs:label "negative regulation of erythrocyte apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) -DisjointClasses( ObjectSomeValuesFrom( )) - -# Class: (positive regulation of erythrocyte apoptotic process) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:rl") Annotation( "PMID:14569084") "Any process that activates or increases the frequency, rate or extent of erythrocyte apoptotic process.") -AnnotationAssertion( ) -AnnotationAssertion( "rl") -AnnotationAssertion( "2013-06-20T19:31:04Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of RBC apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of red blood cell apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of RBC apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of erythrocyte apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of red blood cell apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of RBC apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of erythrocyte apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of red blood cell apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of RBC apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of erythrocyte apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of red blood cell apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of RBC apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of RBC apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of erythrocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of erythrocyte apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of red blood cell apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of red blood cell apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of RBC apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of erythrocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of red blood cell apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of RBC apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of erythrocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of red blood cell apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of RBC apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of erythrocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of red blood cell apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of RBC apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of erythrocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of red blood cell apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902252") -AnnotationAssertion(rdfs:label "positive regulation of erythrocyte apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) -DisjointClasses( ObjectSomeValuesFrom( )) - -# Class: (regulation of apoptotic process involved in outflow tract morphogenesis) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:dph") Annotation( "GOC:mtg_apoptosis") Annotation( "PMID:16839542") "Any process that modulates the frequency, rate or extent of apoptotic process involved in outflow tract morphogenesis.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2013-06-24T19:12:24Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of apoptosis involved in outflow tract morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902256") -AnnotationAssertion(rdfs:label "regulation of apoptotic process involved in outflow tract morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of apoptotic process involved in outflow tract morphogenesis) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:dph") Annotation( "GOC:mtg_apoptosis") Annotation( "PMID:16839542") "Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in outflow tract morphogenesis.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2013-06-24T19:12:30Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of apoptotic process involved in outflow tract morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of apoptotic process involved in outflow tract morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of apoptotic process involved in outflow tract morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of apoptosis involved in outflow tract morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of apoptosis involved in outflow tract morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of apoptosis involved in outflow tract morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of apoptosis involved in outflow tract morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of apoptotic process involved in outflow tract morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of apoptosis involved in outflow tract morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902257") -AnnotationAssertion(rdfs:label "negative regulation of apoptotic process involved in outflow tract morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of apoptotic process involved in outflow tract morphogenesis) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:dph") Annotation( "GOC:mtg_apoptosis") Annotation( "PMID:16839542") "Any process that activates or increases the frequency, rate or extent of apoptotic process involved in outflow tract morphogenesis.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2013-06-24T19:12:42Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of apoptotic process involved in outflow tract morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of apoptotic process involved in outflow tract morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of apoptotic process involved in outflow tract morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of apoptosis involved in outflow tract morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of apoptotic process involved in outflow tract morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of apoptosis involved in outflow tract morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of apoptosis involved in outflow tract morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of apoptosis involved in outflow tract morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of apoptosis involved in outflow tract morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902258") -AnnotationAssertion(rdfs:label "positive regulation of apoptotic process involved in outflow tract morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (apoptotic process involved in blood vessel morphogenesis) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:dph") Annotation( "GOC:mtg_apoptosis") Annotation( "PMID:16163358") "Any apoptotic process that is involved in blood vessel morphogenesis.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2013-06-25T16:16:00Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "apoptotic cell death involved in patterning of blood vessels") -AnnotationAssertion(Annotation( "GOC:TermGenie") "apoptotic programmed cell death involved in patterning of blood vessels") -AnnotationAssertion(Annotation( "GOC:TermGenie") "programmed cell death by apoptosis involved in patterning of blood vessels") -AnnotationAssertion(Annotation( "GOC:TermGenie") "apoptosis involved in patterning of blood vessels") -AnnotationAssertion(Annotation( "GOC:TermGenie") "apoptotic program involved in patterning of blood vessels") -AnnotationAssertion(Annotation( "GOC:TermGenie") "type I programmed cell death involved in patterning of blood vessels") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "signaling (initiator) caspase activity involved in patterning of blood vessels") -AnnotationAssertion( "GO:1902262") -AnnotationAssertion(rdfs:label "apoptotic process involved in blood vessel morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of chromatin organization) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:bf") Annotation( "GOC:vw") Annotation( "GO_REF:0000058") Annotation( "PMID:18314879") "Any process that modulates the frequency, rate or extent of chromatin organization.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2013-07-01T13:21:52Z") -AnnotationAssertion( "GO:0001672") -AnnotationAssertion( "GO:1903308") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of chromatin organisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of establishment or maintenance of chromatin architecture") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "regulation of chromatin assembly or disassembly") -AnnotationAssertion( "regulation of chromatin assembly/disassembly") -AnnotationAssertion( "regulation of chromatin modification") -AnnotationAssertion( "GO:1902275") -AnnotationAssertion(rdfs:label "regulation of chromatin organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of sodium ion transmembrane transport) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:mtg_cardiac_conduct_nov11") Annotation( "GOC:rl") Annotation( "PMID:18591664") "Any process that modulates the frequency, rate or extent of sodium ion transmembrane transport.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2013-07-18T13:33:53Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of sodium ion membrane transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902305") -AnnotationAssertion(rdfs:label "regulation of sodium ion transmembrane transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of sodium ion transmembrane transport) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:mtg_cardiac_conduct_nov11") Annotation( "GOC:rl") Annotation( "PMID:18591664") "Any process that stops, prevents or reduces the frequency, rate or extent of sodium ion transmembrane transport.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2013-07-18T13:34:01Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of sodium ion membrane transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of sodium ion transmembrane transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of sodium ion membrane transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of sodium ion transmembrane transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of sodium ion membrane transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of sodium ion transmembrane transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of sodium ion membrane transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of sodium ion membrane transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of sodium ion transmembrane transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902306") -AnnotationAssertion(rdfs:label "negative regulation of sodium ion transmembrane transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of sodium ion transmembrane transport) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:mtg_cardiac_conduct_nov11") Annotation( "GOC:rl") Annotation( "PMID:18591664") "Any process that activates or increases the frequency, rate or extent of sodium ion transmembrane transport.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2013-07-18T13:34:18Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of sodium ion membrane transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of sodium ion membrane transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of sodium ion transmembrane transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of sodium ion membrane transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of sodium ion transmembrane transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of sodium ion membrane transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of sodium ion transmembrane transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of sodium ion membrane transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of sodium ion transmembrane transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902307") -AnnotationAssertion(rdfs:label "positive regulation of sodium ion transmembrane transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of apoptotic process involved in morphogenesis) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:sart") Annotation( "PMID:12202035") "Any process that modulates the frequency, rate or extent of apoptotic process involved in morphogenesis.") -AnnotationAssertion( "sart") -AnnotationAssertion( "2013-07-29T15:03:16Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of apoptosis involved in morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of apoptosis involved in development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of morphogenetic apoptosis") -AnnotationAssertion( "GO:1902337") -AnnotationAssertion(rdfs:label "regulation of apoptotic process involved in morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of apoptotic process involved in morphogenesis) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:sart") Annotation( "PMID:12202035") "Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in morphogenesis.") -AnnotationAssertion( "sart") -AnnotationAssertion( "2013-07-29T15:03:25Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of apoptotic process involved in morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of apoptotic process involved in morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of apoptotic process involved in morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of apoptosis involved in morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of apoptosis involved in morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of apoptosis involved in morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of apoptosis involved in morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of apoptotic process involved in morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of apoptosis involved in morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of apoptosis involved in development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of morphogenetic apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of apoptosis involved in development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of morphogenetic apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of apoptosis involved in development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of morphogenetic apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of apoptosis involved in development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of morphogenetic apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of apoptosis involved in development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of morphogenetic apoptosis") -AnnotationAssertion( "GO:1902338") -AnnotationAssertion(rdfs:label "negative regulation of apoptotic process involved in morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of apoptotic process involved in morphogenesis) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:sart") Annotation( "PMID:12202035") "Any process that activates or increases the frequency, rate or extent of apoptotic process involved in morphogenesis.") -AnnotationAssertion( "sart") -AnnotationAssertion( "2013-07-29T15:03:33Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of apoptotic process involved in morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of apoptotic process involved in morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of apoptotic process involved in morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of apoptosis involved in morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of apoptotic process involved in morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of apoptosis involved in morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of apoptosis involved in morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of apoptosis involved in morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of apoptosis involved in morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of apoptosis involved in development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of morphogenetic apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of apoptosis involved in development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of morphogenetic apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of apoptosis involved in development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of morphogenetic apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of apoptosis involved in development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of morphogenetic apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of apoptosis involved in development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of morphogenetic apoptosis") -AnnotationAssertion( "GO:1902339") -AnnotationAssertion(rdfs:label "positive regulation of apoptotic process involved in morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of chromosome condensation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "PMID:23219725") "Any process that stops, prevents or reduces the frequency, rate or extent of chromosome condensation.") -AnnotationAssertion( "dgf") -AnnotationAssertion( "2013-07-29T20:54:14Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of chromosome condensation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of eukaryotic chromosome condensation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of nuclear chromosome condensation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of chromosome condensation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of eukaryotic chromosome condensation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of nuclear chromosome condensation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of chromosome condensation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of eukaryotic chromosome condensation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of nuclear chromosome condensation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of eukaryotic chromosome condensation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of nuclear chromosome condensation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of chromosome condensation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of eukaryotic chromosome condensation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of nuclear chromosome condensation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902340") -AnnotationAssertion(rdfs:label "negative regulation of chromosome condensation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (sulfate transmembrane transport) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:dph") Annotation( "PMID:9055073") "The directed movement of sulfate across a membrane.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2013-08-14T14:46:04Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902358") -AnnotationAssertion(rdfs:label "sulfate transmembrane transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (melanocyte apoptotic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:ic") Annotation( "PMID:20530876") "Any apoptotic process in a melanocyte, the main structural component of the epidermis.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2013-08-15T16:35:45Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "melanocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "melanophore apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "melanophore apoptotic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902362") -AnnotationAssertion(rdfs:label "melanocyte apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (negative regulation of RNA catabolic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:bf") Annotation( "PMID:16640457") "Any process that stops, prevents or reduces the frequency, rate or extent of RNA catabolic process.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2013-08-22T14:59:39Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of RNA breakdown") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of RNA catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of RNA catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of RNA degradation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of RNA breakdown") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of RNA catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of RNA catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of RNA degradation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of RNA breakdown") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of RNA catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of RNA catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of RNA degradation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of RNA breakdown") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of RNA catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of RNA degradation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of RNA breakdown") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of RNA catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of RNA catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of RNA degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902369") -AnnotationAssertion(rdfs:label "negative regulation of RNA catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (protein localization to bicellular tight junction) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "PMID:18332111") "A process in which a protein is transported to, or maintained in, a location within a bicellular tight junction.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2013-09-11T21:43:13Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "protein localisation in tight junction") -AnnotationAssertion(Annotation( "GOC:TermGenie") "protein localisation to tight junction") -AnnotationAssertion(Annotation( "GOC:TermGenie") "protein localization in tight junction") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902396") -AnnotationAssertion(rdfs:label "protein localization to bicellular tight junction") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (protein localization to cell junction) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "PMID:18332111") "A process in which a protein is transported to, or maintained in, a location within a cell junction.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2013-09-13T16:55:57Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "protein localisation in cell junction") -AnnotationAssertion(Annotation( "GOC:TermGenie") "protein localisation to cell junction") -AnnotationAssertion(Annotation( "GOC:TermGenie") "protein localization in cell junction") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902414") -AnnotationAssertion(rdfs:label "protein localization to cell junction") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (sulfate import across plasma membrane) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "PMID:14723223") "The directed movement of sulfate from outside of a cell, across the plasma membrane and into the cytosol.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2013-10-07T14:12:38Z") -AnnotationAssertion( "sulfate import into cell") -AnnotationAssertion( "sulphate import into cell") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902434") -AnnotationAssertion(rdfs:label "sulfate import across plasma membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of stem cell population maintenance) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:hjd") Annotation( "PMID:22969033") "Any process that stops, prevents or reduces the frequency, rate or extent of stem cell population maintenance.") -AnnotationAssertion( "cjm") -AnnotationAssertion( "2013-10-16T22:19:17Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of stem cell maintenance") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of stem cell maintenance") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of stem cell maintenance") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of stem cell maintenance") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of maintenance of pluripotency") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of maintenance of pluripotency") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of maintenance of pluripotency") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of maintenance of pluripotency") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of maintenance of pluripotency") -AnnotationAssertion( "GO:1902455") -AnnotationAssertion(rdfs:label "negative regulation of stem cell population maintenance") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of stem cell population maintenance) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:hjd") Annotation( "PMID:22969033") "Any process that activates or increases the frequency, rate or extent of stem cell population maintenance.") -AnnotationAssertion( "cjm") -AnnotationAssertion( "2013-10-16T22:27:47Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of stem cell maintenance") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of stem cell maintenance") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of stem cell maintenance") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of stem cell maintenance") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of maintenance of pluripotency") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of maintenance of pluripotency") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of maintenance of pluripotency") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of maintenance of pluripotency") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of maintenance of pluripotency") -AnnotationAssertion( "GO:1902459") -AnnotationAssertion(rdfs:label "positive regulation of stem cell population maintenance") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (protein localization to cell leading edge) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:lb") Annotation( "PMID:21543326") "A process in which a protein is transported to, or maintained in, a location within a cell leading edge.") -AnnotationAssertion( "jl") -AnnotationAssertion( "2013-10-22T12:36:07Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "protein localisation in cell leading edge") -AnnotationAssertion(Annotation( "GOC:TermGenie") "protein localisation to cell leading edge") -AnnotationAssertion(Annotation( "GOC:TermGenie") "protein localization in cell leading edge") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902463") -AnnotationAssertion(rdfs:label "protein localization to cell leading edge") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of protein localization to synapse) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:kmv") Annotation( "PMID:22588719") "Any process that modulates the frequency, rate or extent of protein localization to synapse.") -AnnotationAssertion( "kmv") -AnnotationAssertion( "2013-10-25T15:09:09Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of protein localisation to synapse") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902473") -AnnotationAssertion(rdfs:label "regulation of protein localization to synapse") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of protein localization to synapse) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:kmv") Annotation( "PMID:22588719") "Any process that activates or increases the frequency, rate or extent of protein localization to synapse.") -AnnotationAssertion( "kmv") -AnnotationAssertion( "2013-10-25T15:09:18Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of protein localisation to synapse") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of protein localisation to synapse") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of protein localization to synapse") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of protein localisation to synapse") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of protein localization to synapse") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of protein localisation to synapse") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of protein localization to synapse") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of protein localisation to synapse") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of protein localization to synapse") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902474") -AnnotationAssertion(rdfs:label "positive regulation of protein localization to synapse") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (L-alpha-amino acid transmembrane transport) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:kmv") Annotation( "PMID:14668347") "The directed movement of L-alpha-amino acid across a membrane.") -AnnotationAssertion( "kmv") -AnnotationAssertion( "2013-10-25T15:17:39Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902475") -AnnotationAssertion(rdfs:label "L-alpha-amino acid transmembrane transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (Sertoli cell apoptotic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:ic") Annotation( "PMID:17761895") "Any apoptotic process in a Sertoli cell.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2013-11-06T11:27:34Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "Sertoli cell apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902484") -AnnotationAssertion(rdfs:label "Sertoli cell apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cholangiocyte apoptotic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "PMID:22961800") "Any apoptotic process in a cholangiocyte.") -AnnotationAssertion( "cls") -AnnotationAssertion( "2013-11-12T15:30:08Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "epithelial cell of bile duct apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "cholangiocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "epithelial cell of bile duct apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902488") -AnnotationAssertion(rdfs:label "cholangiocyte apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (hepatoblast apoptotic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "PMID:22412967") "Any apoptotic process in a hepatoblast.") -AnnotationAssertion( "cls") -AnnotationAssertion( "2013-11-12T17:02:52Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "hepatoblast apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902489") -AnnotationAssertion(rdfs:label "hepatoblast apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of sperm capacitation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:hjd") Annotation( "PMID:22539676") "Any process that modulates the frequency, rate or extent of sperm capacitation.") -AnnotationAssertion( "hjd") -AnnotationAssertion( "2013-11-12T21:17:03Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of sperm activation") -AnnotationAssertion( "GO:1902490") -AnnotationAssertion(rdfs:label "regulation of sperm capacitation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of sperm capacitation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:hjd") Annotation( "PMID:22539676") "Any process that stops, prevents or reduces the frequency, rate or extent of sperm capacitation.") -AnnotationAssertion( "hjd") -AnnotationAssertion( "2013-11-12T21:17:12Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of sperm capacitation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of sperm capacitation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of sperm capacitation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of sperm capacitation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of sperm activation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of sperm activation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of sperm activation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of sperm activation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of sperm activation") -AnnotationAssertion( "GO:1902491") -AnnotationAssertion(rdfs:label "negative regulation of sperm capacitation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of sperm capacitation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:hjd") Annotation( "PMID:22539676") "Any process that activates or increases the frequency, rate or extent of sperm capacitation.") -AnnotationAssertion( "hjd") -AnnotationAssertion( "2013-11-12T21:17:21Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of sperm capacitation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of sperm capacitation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of sperm capacitation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of sperm capacitation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of sperm activation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of sperm activation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of sperm activation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of sperm activation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of sperm activation") -AnnotationAssertion( "GO:1902492") -AnnotationAssertion(rdfs:label "positive regulation of sperm capacitation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (catalytic complex) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:bhm") Annotation( "PMID:8077207") "A protein complex which is capable of catalytic activity.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/19980"^^xsd:anyURI) -AnnotationAssertion( "bhm") -AnnotationAssertion( "2013-11-13T16:18:47Z") -AnnotationAssertion(Annotation( "GOC:bhm") Annotation( "GOC:jl") "enzyme complex") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:1902494") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "catalytic complex") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (transmembrane transporter complex) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:bhm") Annotation( "PMID:18024586") "A transmembrane protein complex which enables the transfer of a substance from one side of a membrane to the other.") -AnnotationAssertion( "bhm") -AnnotationAssertion( "2013-11-13T16:23:04Z") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:1902495") -AnnotationAssertion(rdfs:label "transmembrane transporter complex") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (regulation of apoptotic DNA fragmentation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:hjd") Annotation( "PMID:15572351") Annotation( "PMID:15723341") "Any process that modulates the frequency, rate or extent of apoptotic DNA fragmentation.") -AnnotationAssertion( "hjd") -AnnotationAssertion( "2013-11-15T18:28:32Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of DNA fragmentation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of chromatinolysis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of DNA catabolic process during apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of DNA catabolism during apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of DNA fragmentation involved in apoptotic nuclear change") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of endonucleolytic DNA catabolic process involved in apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902510") -AnnotationAssertion(rdfs:comment "DNA fragmentation in response to apoptotic signals is achieved through the activity of apoptotic nucleases (see GO:0006309 'apoptotic DNA fragmentation'). Gene products involved in compartmentalization of such nucleases and in activation or repression of their enzymatic activity should be annotated to the regulation term GO:1902510 'regulation of apoptotic DNA fragmentation' or to one of its children (see PMID:15723341).") -AnnotationAssertion(rdfs:label "regulation of apoptotic DNA fragmentation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of apoptotic DNA fragmentation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:hjd") Annotation( "PMID:15572351") "Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic DNA fragmentation.") -AnnotationAssertion( "hjd") -AnnotationAssertion( "2013-11-15T18:28:41Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of DNA catabolic process during apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of DNA catabolism during apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of DNA fragmentation involved in apoptotic nuclear change") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of apoptotic DNA fragmentation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of endonucleolytic DNA catabolic process involved in apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of DNA catabolic process during apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of DNA catabolism during apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of DNA fragmentation involved in apoptotic nuclear change") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of apoptotic DNA fragmentation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of endonucleolytic DNA catabolic process involved in apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of DNA catabolic process during apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of DNA catabolism during apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of DNA fragmentation involved in apoptotic nuclear change") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of apoptotic DNA fragmentation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of endonucleolytic DNA catabolic process involved in apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of DNA catabolic process during apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of DNA catabolism during apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of DNA fragmentation involved in apoptotic nuclear change") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of endonucleolytic DNA catabolic process involved in apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of DNA catabolic process during apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of DNA catabolism during apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of DNA fragmentation involved in apoptotic nuclear change") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of apoptotic DNA fragmentation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of endonucleolytic DNA catabolic process involved in apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902511") -AnnotationAssertion(rdfs:label "negative regulation of apoptotic DNA fragmentation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of apoptotic DNA fragmentation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:hjd") Annotation( "PMID:15572351") "Any process that activates or increases the frequency, rate or extent of apoptotic DNA fragmentation.") -AnnotationAssertion( "hjd") -AnnotationAssertion( "2013-11-15T18:28:50Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of DNA catabolic process during apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of DNA catabolism during apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of DNA fragmentation involved in apoptotic nuclear change") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of endonucleolytic DNA catabolic process involved in apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of DNA catabolic process during apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of DNA catabolism during apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of DNA fragmentation involved in apoptotic nuclear change") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of apoptotic DNA fragmentation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of endonucleolytic DNA catabolic process involved in apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of DNA catabolic process during apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of DNA catabolism during apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of DNA fragmentation involved in apoptotic nuclear change") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of apoptotic DNA fragmentation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of endonucleolytic DNA catabolic process involved in apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of DNA catabolic process during apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of DNA catabolism during apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of DNA fragmentation involved in apoptotic nuclear change") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of apoptotic DNA fragmentation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of endonucleolytic DNA catabolic process involved in apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of DNA catabolic process during apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of DNA catabolism during apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of DNA fragmentation involved in apoptotic nuclear change") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of apoptotic DNA fragmentation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of endonucleolytic DNA catabolic process involved in apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902512") -AnnotationAssertion(rdfs:label "positive regulation of apoptotic DNA fragmentation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of organelle transport along microtubule) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:dph") Annotation( "PMID:21147087") "Any process that modulates the frequency, rate or extent of organelle transport along microtubule.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2013-11-15T20:15:17Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of microtubule-based organelle localization") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902513") -AnnotationAssertion(rdfs:label "regulation of organelle transport along microtubule") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of intracellular signal transduction) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:dph") Annotation( "GOC:signaling") Annotation( "GOC:tb") "Any process that modulates the frequency, rate or extent of intracellular signal transduction.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2013-12-02T11:32:52Z") -AnnotationAssertion( "GO:0010627") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of intracellular signaling cascade") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of intracellular signaling chain") -AnnotationAssertion( "regulation of intracellular protein kinase cascade") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of intracellular signal transduction pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of signal transmission via intracellular cascade") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of intracellular signaling pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of signal transduction via intracellular signaling cascade") -AnnotationAssertion( "GO:1902531") -AnnotationAssertion(rdfs:label "regulation of intracellular signal transduction") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of intracellular signal transduction) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:dph") Annotation( "GOC:signaling") Annotation( "GOC:tb") "Any process that stops, prevents or reduces the frequency, rate or extent of intracellular signal transduction.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2013-12-02T11:33:01Z") -AnnotationAssertion( "GO:0010741") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of intracellular signal transduction") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of intracellular signaling chain") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of intracellular signal transduction") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of intracellular signaling chain") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of intracellular signal transduction") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of intracellular signaling chain") -AnnotationAssertion( "negative regulation of intracellular protein kinase cascade") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of intracellular signaling cascade") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of intracellular signaling chain") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of intracellular signal transduction pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of intracellular signaling cascade") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of signal transmission via intracellular cascade") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of intracellular signal transduction pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of intracellular signal transduction pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of intracellular signaling cascade") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of signal transmission via intracellular cascade") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of intracellular signal transduction") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of intracellular signal transduction pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of intracellular signaling cascade") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of intracellular signaling chain") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of signal transmission via intracellular cascade") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of intracellular signal transduction pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of signal transmission via intracellular cascade") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of intracellular signaling pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of signal transduction via intracellular signaling cascade") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of intracellular signaling cascade") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of intracellular signaling pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of signal transduction via intracellular signaling cascade") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of signal transmission via intracellular cascade") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of intracellular signaling pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of signal transduction via intracellular signaling cascade") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of intracellular signaling pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of signal transduction via intracellular signaling cascade") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of intracellular signaling pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of signal transduction via intracellular signaling cascade") -AnnotationAssertion( "GO:1902532") -AnnotationAssertion(rdfs:label "negative regulation of intracellular signal transduction") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of intracellular signal transduction) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:dph") Annotation( "GOC:signaling") Annotation( "GOC:tb") "Any process that activates or increases the frequency, rate or extent of intracellular signal transduction.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2013-12-02T11:33:10Z") -AnnotationAssertion( "GO:0010740") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of intracellular signaling chain") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of intracellular signal transduction") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of intracellular signaling chain") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of intracellular signal transduction") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of intracellular signaling chain") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of intracellular signal transduction") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of intracellular signaling chain") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of intracellular signal transduction") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of intracellular signal transduction pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of intracellular signaling cascade") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of intracellular signaling chain") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of signal transmission via intracellular cascade") -AnnotationAssertion( "positive regulation of intracellular protein kinase cascade") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of intracellular signal transduction pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of signal transmission via intracellular cascade") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of intracellular signal transduction pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of signal transmission via intracellular cascade") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of intracellular signal transduction pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of signal transmission via intracellular cascade") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of intracellular signal transduction pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of signal transmission via intracellular cascade") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of intracellular signaling pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of signal transduction via intracellular signaling cascade") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of intracellular signaling cascade") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of intracellular signaling pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of signal transduction via intracellular signaling cascade") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of intracellular signaling cascade") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of intracellular signaling pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of signal transduction via intracellular signaling cascade") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of intracellular signaling cascade") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of intracellular signaling pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of signal transduction via intracellular signaling cascade") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of intracellular signaling cascade") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of intracellular signaling pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of signal transduction via intracellular signaling cascade") -AnnotationAssertion( "GO:1902533") -AnnotationAssertion(rdfs:label "positive regulation of intracellular signal transduction") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of neutrophil activation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "PMID:17588661") "Any process that modulates the frequency, rate or extent of neutrophil activation.") -AnnotationAssertion( "ecu") -AnnotationAssertion( "2013-12-10T15:33:08Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902563") -AnnotationAssertion(rdfs:label "regulation of neutrophil activation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of neutrophil activation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "PMID:17588661") "Any process that stops, prevents or reduces the frequency, rate or extent of neutrophil activation.") -AnnotationAssertion( "ecu") -AnnotationAssertion( "2013-12-10T15:33:16Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of neutrophil activation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of neutrophil activation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of neutrophil activation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of neutrophil activation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902564") -AnnotationAssertion(rdfs:label "negative regulation of neutrophil activation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of neutrophil activation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "PMID:17588661") "Any process that activates or increases the frequency, rate or extent of neutrophil activation.") -AnnotationAssertion( "ecu") -AnnotationAssertion( "2013-12-10T15:33:26Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of neutrophil activation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of neutrophil activation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of neutrophil activation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of neutrophil activation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902565") -AnnotationAssertion(rdfs:label "positive regulation of neutrophil activation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (protein localization to nucleolus) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "PMID:22809626") "A process in which a protein is transported to, or maintained in, a location within a nucleolus.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2013-12-10T16:25:28Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "protein localisation in nucleolus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "protein localisation to nucleolus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "protein localization in nucleolus") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902570") -AnnotationAssertion(rdfs:label "protein localization to nucleolus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of response to water deprivation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:24198318") "Any process that activates or increases the frequency, rate or extent of response to water deprivation.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2013-12-19T00:31:58Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of response to dehydration") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of response to drought") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of response to thirst") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of response to dehydration") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of response to drought") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of response to thirst") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of response to water deprivation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of response to dehydration") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of response to drought") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of response to thirst") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of response to water deprivation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of response to dehydration") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of response to drought") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of response to thirst") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of response to water deprivation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of response to dehydration") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of response to drought") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of response to thirst") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of response to water deprivation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of drought tolerance") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of drought tolerance") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of drought tolerance") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of drought tolerance") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of drought tolerance") -AnnotationAssertion( "GO:1902584") -AnnotationAssertion(rdfs:label "positive regulation of response to water deprivation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of neutrophil migration) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:1826836") "Any process that modulates the frequency, rate or extent of neutrophil migration.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2014-01-15T18:58:39Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902622") -AnnotationAssertion(rdfs:label "regulation of neutrophil migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of neutrophil migration) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:1826836") "Any process that stops, prevents or reduces the frequency, rate or extent of neutrophil migration.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2014-01-15T18:58:49Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of neutrophil migration") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of neutrophil migration") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of neutrophil migration") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of neutrophil migration") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902623") -AnnotationAssertion(rdfs:label "negative regulation of neutrophil migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of neutrophil migration) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:1826836") "Any process that activates or increases the frequency, rate or extent of neutrophil migration.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2014-01-15T18:58:58Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of neutrophil migration") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of neutrophil migration") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of neutrophil migration") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of neutrophil migration") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902624") -AnnotationAssertion(rdfs:label "positive regulation of neutrophil migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (neural crest cell differentiation involved in thymus development) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:nhn") Annotation( "GO_REF:0000060") Annotation( "PMID:15741317") Annotation( "PMID:18292542") "Any neural crest cell differentiation that is involved in thymus development.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2014-01-21T10:03:20Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902637") -AnnotationAssertion(rdfs:label "neural crest cell differentiation involved in thymus development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (neural crest cell differentiation involved in parathyroid gland development) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:nhn") Annotation( "GO_REF:0000060") Annotation( "PMID:15741317") "Any neural crest cell differentiation that is involved in parathyroid gland development.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2014-01-21T10:03:29Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902638") -AnnotationAssertion(rdfs:label "neural crest cell differentiation involved in parathyroid gland development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (carbon dioxide binding) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:bhm") Annotation( "GO_REF:0000067") Annotation( "PMID:15491402") "Binding to carbon dioxide.") -AnnotationAssertion( "bhm") -AnnotationAssertion( "2014-02-04T10:38:41Z") -AnnotationAssertion( "CO2 binding") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:1902670") -AnnotationAssertion(rdfs:label "carbon dioxide binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of RNA biosynthetic process) - -AnnotationAssertion(Annotation( "GO:jl") Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") "Any process that stops, prevents or reduces the frequency, rate or extent of RNA biosynthetic process.") -AnnotationAssertion( "jl") -AnnotationAssertion( "2014-02-05T16:32:01Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of RNA anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of RNA biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of RNA biosynthetic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of RNA formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of RNA synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of RNA anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of RNA biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of RNA biosynthetic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of RNA formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of RNA synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of RNA anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of RNA biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of RNA biosynthetic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of RNA formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of RNA synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of RNA anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of RNA biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of RNA formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of RNA synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of RNA anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of RNA biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of RNA biosynthetic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of RNA formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of RNA synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902679") -AnnotationAssertion(rdfs:label "negative regulation of RNA biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of RNA biosynthetic process) - -AnnotationAssertion(Annotation( "GO:jl") Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") "Any process that activates or increases the frequency, rate or extent of RNA biosynthetic process.") -AnnotationAssertion( "jl") -AnnotationAssertion( "2014-02-05T16:32:10Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of RNA anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of RNA biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of RNA formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of RNA synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of RNA anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of RNA biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of RNA biosynthetic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of RNA formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of RNA synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of RNA anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of RNA biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of RNA biosynthetic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of RNA formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of RNA synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of RNA anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of RNA biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of RNA biosynthetic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of RNA formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of RNA synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of RNA anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of RNA biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of RNA biosynthetic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of RNA formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of RNA synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902680") -AnnotationAssertion(rdfs:label "positive regulation of RNA biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of receptor localization to synapse) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:kmv") Annotation( "GO_REF:0000058") Annotation( "PMID:22252129") "Any process that modulates the frequency, rate or extent of receptor localization to synapse.") -AnnotationAssertion( "kmv") -AnnotationAssertion( "2014-02-07T17:38:31Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of receptor localisation to synapse") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902683") -AnnotationAssertion(rdfs:label "regulation of receptor localization to synapse") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of receptor localization to synapse) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:kmv") Annotation( "GO_REF:0000058") Annotation( "PMID:22252129") "Any process that stops, prevents or reduces the frequency, rate or extent of receptor localization to synapse.") -AnnotationAssertion( "kmv") -AnnotationAssertion( "2014-02-07T17:38:41Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of receptor localisation to synapse") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of receptor localization to synapse") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of receptor localisation to synapse") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of receptor localization to synapse") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of receptor localisation to synapse") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of receptor localization to synapse") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of receptor localisation to synapse") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of receptor localisation to synapse") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of receptor localization to synapse") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902684") -AnnotationAssertion(rdfs:label "negative regulation of receptor localization to synapse") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of receptor localization to synapse) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:kmv") Annotation( "GO_REF:0000058") Annotation( "PMID:22252129") "Any process that activates or increases the frequency, rate or extent of receptor localization to synapse.") -AnnotationAssertion( "kmv") -AnnotationAssertion( "2014-02-07T17:38:51Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of receptor localisation to synapse") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of receptor localisation to synapse") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of receptor localization to synapse") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of receptor localisation to synapse") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of receptor localization to synapse") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of receptor localisation to synapse") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of receptor localization to synapse") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of receptor localisation to synapse") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of receptor localization to synapse") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902685") -AnnotationAssertion(rdfs:label "positive regulation of receptor localization to synapse") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of neuroblast proliferation) - -AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "GO_REF:0000058") Annotation( "PMID:21168496") "Any process that modulates the frequency, rate or extent of neuroblast proliferation.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2014-02-18T10:03:31Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902692") -AnnotationAssertion(rdfs:label "regulation of neuroblast proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (pentose catabolic process to butyrate) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mengo_curators") Annotation( "GO_REF:0000093") Annotation( "PMID:18727018") Annotation( "PMID:19539744") "The chemical reactions and pathways resulting in the breakdown of pentose to butyrate.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2014-02-19T18:28:28Z") -AnnotationAssertion( "GO:1990288") -AnnotationAssertion(Annotation( "GOC:tt") "acidogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "pentose breakdown to butyrate") -AnnotationAssertion(Annotation( "GOC:TermGenie") "pentose catabolism to butyrate") -AnnotationAssertion(Annotation( "GOC:TermGenie") "pentose degradation to butyrate") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902698") -AnnotationAssertion(rdfs:label "pentose catabolic process to butyrate") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (pentose catabolic process to acetate) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mengo_curators") Annotation( "GO_REF:0000093") Annotation( "PMID:18727018") Annotation( "PMID:19539744") "The chemical reactions and pathways resulting in the breakdown of pentose to acetate.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2014-02-19T18:28:38Z") -AnnotationAssertion( "GO:1990289") -AnnotationAssertion(Annotation( "GOC:tt") "acidogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "pentose breakdown to acetate") -AnnotationAssertion(Annotation( "GOC:TermGenie") "pentose catabolism to acetate") -AnnotationAssertion(Annotation( "GOC:TermGenie") "pentose degradation to acetate") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902699") -AnnotationAssertion(rdfs:label "pentose catabolic process to acetate") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (GABA receptor complex) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:bhm") Annotation( "GO_REF:0000088") Annotation( "PMID:18790874") "A protein complex which is capable of GABA receptor activity. Upon binding of gamma-aminobutyric acid (GABA) it transmits the signal from one side of the membrane to the other to initiate a change in cell activity. Major inhibitory receptor in vertebrate brain. Also found in other vertebrate tissues, invertebrates and possibly in plants. Effective benzodiazepine receptor.") -AnnotationAssertion( "bhm") -AnnotationAssertion( "2014-02-20T16:07:48Z") -AnnotationAssertion( "gamma-aminobutyric acid receptor complex") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:1902710") -AnnotationAssertion(rdfs:label "GABA receptor complex") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of prolactin secretion) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:16159377") "Any process that stops, prevents or reduces the frequency, rate or extent of prolactin secretion.") -AnnotationAssertion( "mr") -AnnotationAssertion( "2014-02-24T16:09:28Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of prolactin secretion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of prolactin secretion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of prolactin secretion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of prolactin secretion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902721") -AnnotationAssertion(rdfs:label "negative regulation of prolactin secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of prolactin secretion) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:16159377") "Any process that activates or increases the frequency, rate or extent of prolactin secretion.") -AnnotationAssertion( "mr") -AnnotationAssertion( "2014-02-24T16:09:37Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of prolactin secretion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of prolactin secretion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of prolactin secretion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of prolactin secretion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902722") -AnnotationAssertion(rdfs:label "positive regulation of prolactin secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of proteoglycan biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:23212449") "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans.") -AnnotationAssertion( "mr") -AnnotationAssertion( "2014-02-24T16:10:43Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of proteoglycan anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of proteoglycan biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of proteoglycan biosynthetic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of proteoglycan formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of proteoglycan synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of proteoglycan anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of proteoglycan biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of proteoglycan biosynthetic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of proteoglycan formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of proteoglycan synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of proteoglycan anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of proteoglycan biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of proteoglycan biosynthetic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of proteoglycan formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of proteoglycan synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of proteoglycan anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of proteoglycan biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of proteoglycan formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of proteoglycan synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of proteoglycan anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of proteoglycan biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of proteoglycan biosynthetic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of proteoglycan formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of proteoglycan synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902729") -AnnotationAssertion(rdfs:label "negative regulation of proteoglycan biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of proteoglycan biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:23212449") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans.") -AnnotationAssertion( "mr") -AnnotationAssertion( "2014-02-24T16:10:52Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of proteoglycan anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of proteoglycan biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of proteoglycan formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of proteoglycan synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of proteoglycan anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of proteoglycan biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of proteoglycan biosynthetic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of proteoglycan formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of proteoglycan synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of proteoglycan anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of proteoglycan biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of proteoglycan biosynthetic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of proteoglycan formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of proteoglycan synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of proteoglycan anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of proteoglycan biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of proteoglycan biosynthetic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of proteoglycan formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of proteoglycan synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of proteoglycan anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of proteoglycan biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of proteoglycan biosynthetic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of proteoglycan formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of proteoglycan synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902730") -AnnotationAssertion(rdfs:label "positive regulation of proteoglycan biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of growth plate cartilage chondrocyte differentiation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:23212449") "Any process that modulates the rate, frequency, or extent of the process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte that will contribute to the growth of a bone. A chondrocyte is a polymorphic cell that forms cartilage.") -AnnotationAssertion( "mr") -AnnotationAssertion( "2014-02-24T16:11:28Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902733") -AnnotationAssertion(rdfs:label "regulation of growth plate cartilage chondrocyte differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of chondrocyte differentiation involved in endochondral bone morphogenesis) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:8662546") "Any process that modulates the rate, frequency, or extent of the process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte that will contribute to the development of a bone. A chondrocyte is a polymorphic cell that forms cartilage.") -AnnotationAssertion( "mr") -AnnotationAssertion( "2014-02-26T15:36:15Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902738") -AnnotationAssertion(rdfs:label "regulation of chondrocyte differentiation involved in endochondral bone morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (apoptotic process involved in development) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:pg") Annotation( "GO_REF:0000060") "Any apoptotic process that is involved in anatomical structure development.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2014-02-28T13:09:43Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "apoptotic cell death involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "apoptotic cell death involved in development of an anatomical structure") -AnnotationAssertion( "apoptotic process involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "apoptotic process involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "apoptotic programmed cell death involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "apoptotic programmed cell death involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "programmed cell death by apoptosis involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "programmed cell death by apoptosis involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of apoptosis involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of apoptosis involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "apoptosis involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "apoptosis involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "apoptosis signaling involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "apoptosis signaling involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "apoptotic program involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "apoptotic program involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "type I programmed cell death involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "type I programmed cell death involved in development of an anatomical structure") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "apoptosis activator activity involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "apoptosis activator activity involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "commitment to apoptosis involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "commitment to apoptosis involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "induction of apoptosis by p53 involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "induction of apoptosis by p53 involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "induction of apoptosis involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "induction of apoptosis involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "signaling (initiator) caspase activity involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "signaling (initiator) caspase activity involved in development of an anatomical structure") -AnnotationAssertion( "GO:1902742") -AnnotationAssertion(rdfs:label "apoptotic process involved in development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of lens fiber cell differentiation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mr") Annotation( "GO_REF:0000058") Annotation( "PMID:17592637") "Any process that modulates the frequency, rate or extent of lens fiber cell differentiation.") -AnnotationAssertion( "mr") -AnnotationAssertion( "2014-03-03T23:18:50Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of lens fibre cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902746") -AnnotationAssertion(rdfs:label "regulation of lens fiber cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of lens fiber cell differentiation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mr") Annotation( "GO_REF:0000058") Annotation( "PMID:17592637") "Any process that stops, prevents or reduces the frequency, rate or extent of lens fiber cell differentiation.") -AnnotationAssertion( "mr") -AnnotationAssertion( "2014-03-03T23:19:32Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of lens fiber cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of lens fibre cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of lens fiber cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of lens fibre cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of lens fiber cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of lens fibre cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of lens fibre cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of lens fiber cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of lens fibre cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902747") -AnnotationAssertion(rdfs:label "negative regulation of lens fiber cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of lens fiber cell differentiation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mr") Annotation( "GO_REF:0000058") Annotation( "PMID:17592637") "Any process that activates or increases the frequency, rate or extent of lens fiber cell differentiation.") -AnnotationAssertion( "mr") -AnnotationAssertion( "2014-03-03T23:20:12Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of lens fibre cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of lens fiber cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of lens fibre cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of lens fiber cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of lens fibre cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of lens fiber cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of lens fibre cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of lens fiber cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of lens fibre cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902748") -AnnotationAssertion(rdfs:label "positive regulation of lens fiber cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of chondrocyte development) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mr") Annotation( "GO_REF:0000058") Annotation( "PMID:16575901") "Any process that activates or increases the frequency, rate or extent of chondrocyte development.") -AnnotationAssertion( "mr") -AnnotationAssertion( "2014-03-07T17:45:55Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of chondrocyte development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of chondrocyte development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of chondrocyte development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of chondrocyte development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902761") -AnnotationAssertion(rdfs:label "positive regulation of chondrocyte development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (response to alkane) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mengo_curators") Annotation( "GO_REF:0000071") Annotation( "PMID:22958739") Annotation( "PMID:23826995") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkane stimulus.") -AnnotationAssertion( "GO:1990373") -AnnotationAssertion( "process resulting in tolerance to alkane") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902778") -AnnotationAssertion(rdfs:label "response to alkane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cellular response to alkane) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mengo_curators") Annotation( "GO_REF:0000071") Annotation( "PMID:22958739") Annotation( "PMID:23826995") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkane stimulus.") -AnnotationAssertion( "tt") -AnnotationAssertion( "2014-03-21T03:18:04Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902779") -AnnotationAssertion(rdfs:label "cellular response to alkane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of skeletal muscle fiber differentiation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mr") Annotation( "GO_REF:0000058") Annotation( "PMID:17879321") "Any process that modulates the frequency, rate or extent of skeletal muscle fiber differentiation.") -AnnotationAssertion( "mr") -AnnotationAssertion( "2014-03-26T21:18:26Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902809") -AnnotationAssertion(rdfs:label "regulation of skeletal muscle fiber differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of skeletal muscle fiber differentiation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mr") Annotation( "GO_REF:0000058") Annotation( "PMID:17879321") "Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle fiber differentiation.") -AnnotationAssertion( "mr") -AnnotationAssertion( "2014-03-26T21:18:32Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of skeletal muscle fiber differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of skeletal muscle fiber differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of skeletal muscle fiber differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of skeletal muscle fiber differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902810") -AnnotationAssertion(rdfs:label "negative regulation of skeletal muscle fiber differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of skeletal muscle fiber differentiation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mr") Annotation( "GO_REF:0000058") Annotation( "PMID:17879321") "Any process that activates or increases the frequency, rate or extent of skeletal muscle fiber differentiation.") -AnnotationAssertion( "mr") -AnnotationAssertion( "2014-03-26T21:18:38Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of skeletal muscle fiber differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of skeletal muscle fiber differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of skeletal muscle fiber differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of skeletal muscle fiber differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902811") -AnnotationAssertion(rdfs:label "positive regulation of skeletal muscle fiber differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of protein localization to microtubule) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:vw") Annotation( "GO_REF:0000058") Annotation( "PMID:23087209") "Any process that modulates the frequency, rate or extent of protein localization to microtubule.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2014-03-27T22:07:12Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of protein localisation to microtubule") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902816") -AnnotationAssertion(rdfs:label "regulation of protein localization to microtubule") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of protein localization to microtubule) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:vw") Annotation( "GO_REF:0000058") Annotation( "PMID:23087209") "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to microtubule.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2014-03-27T22:07:18Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of protein localisation to microtubule") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of protein localization to microtubule") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of protein localisation to microtubule") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of protein localization to microtubule") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of protein localisation to microtubule") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of protein localization to microtubule") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of protein localisation to microtubule") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of protein localisation to microtubule") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of protein localization to microtubule") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902817") -AnnotationAssertion(rdfs:label "negative regulation of protein localization to microtubule") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of cell proliferation in dorsal spinal cord) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mr") Annotation( "GO_REF:0000058") Annotation( "PMID:21730158") "Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation in dorsal spinal cord.") -AnnotationAssertion( "mr") -AnnotationAssertion( "2014-03-31T17:42:50Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of cell proliferation in dorsal spinal cord") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of cell proliferation in dorsal spinal cord") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of cell proliferation in dorsal spinal cord") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of cell proliferation in dorsal spinal cord") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902832") -AnnotationAssertion(rdfs:label "negative regulation of cell proliferation in dorsal spinal cord") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of cell proliferation in dorsal spinal cord) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mr") Annotation( "GO_REF:0000058") Annotation( "PMID:21730158") "Any process that activates or increases the frequency, rate or extent of cell proliferation in dorsal spinal cord.") -AnnotationAssertion( "mr") -AnnotationAssertion( "2014-03-31T17:43:33Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of cell proliferation in dorsal spinal cord") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of cell proliferation in dorsal spinal cord") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of cell proliferation in dorsal spinal cord") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of cell proliferation in dorsal spinal cord") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902833") -AnnotationAssertion(rdfs:label "positive regulation of cell proliferation in dorsal spinal cord") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of nuclear migration along microtubule) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:23087209") "Any process that modulates the frequency, rate or extent of nuclear migration along microtubule.") -AnnotationAssertion( "vw") -AnnotationAssertion( "2014-04-01T13:50:23Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of nuclear movement, microtubule-mediated") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of nucleus migration") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of microtubule cytoskeleton-dependent nuclear positioning") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of microtubule cytoskeleton-dependent nucleus positioning") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of microtubule-dependent nuclear positioning") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of microtubule-dependent nucleus positioning") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of microtubule-mediated nuclear migration") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of nuclear migration, microtubule-mediated") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of transport of nucleus by microtubules") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of transport of nucleus, microtubule-mediated") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902838") -AnnotationAssertion(rdfs:label "regulation of nuclear migration along microtubule") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of nuclear migration along microtubule) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:23087209") "Any process that stops, prevents or reduces the frequency, rate or extent of nuclear migration along microtubule.") -AnnotationAssertion( "vw") -AnnotationAssertion( "2014-04-01T13:50:29Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of microtubule cytoskeleton-dependent nuclear positioning") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of microtubule cytoskeleton-dependent nucleus positioning") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of microtubule-dependent nuclear positioning") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of microtubule-dependent nucleus positioning") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of microtubule-mediated nuclear migration") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of nuclear migration along microtubule") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of nuclear migration, microtubule-mediated") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of transport of nucleus by microtubules") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of transport of nucleus, microtubule-mediated") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of microtubule cytoskeleton-dependent nuclear positioning") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of microtubule cytoskeleton-dependent nucleus positioning") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of microtubule-dependent nuclear positioning") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of microtubule-dependent nucleus positioning") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of microtubule-mediated nuclear migration") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of nuclear migration along microtubule") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of nuclear migration, microtubule-mediated") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of transport of nucleus by microtubules") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of transport of nucleus, microtubule-mediated") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of microtubule cytoskeleton-dependent nuclear positioning") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of microtubule cytoskeleton-dependent nucleus positioning") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of microtubule-dependent nuclear positioning") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of microtubule-dependent nucleus positioning") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of microtubule-mediated nuclear migration") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of nuclear migration along microtubule") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of nuclear migration, microtubule-mediated") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of transport of nucleus by microtubules") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of transport of nucleus, microtubule-mediated") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of microtubule cytoskeleton-dependent nuclear positioning") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of microtubule cytoskeleton-dependent nucleus positioning") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of microtubule-dependent nuclear positioning") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of microtubule-dependent nucleus positioning") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of microtubule-mediated nuclear migration") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of nuclear migration, microtubule-mediated") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of transport of nucleus by microtubules") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of transport of nucleus, microtubule-mediated") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of microtubule cytoskeleton-dependent nuclear positioning") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of microtubule cytoskeleton-dependent nucleus positioning") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of microtubule-dependent nuclear positioning") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of microtubule-dependent nucleus positioning") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of microtubule-mediated nuclear migration") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of nuclear migration along microtubule") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of nuclear migration, microtubule-mediated") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of transport of nucleus by microtubules") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of transport of nucleus, microtubule-mediated") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902839") -AnnotationAssertion(rdfs:label "negative regulation of nuclear migration along microtubule") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of nuclear migration along microtubule) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:23087209") "Any process that activates or increases the frequency, rate or extent of nuclear migration along microtubule.") -AnnotationAssertion( "vw") -AnnotationAssertion( "2014-04-01T13:50:35Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of microtubule cytoskeleton-dependent nuclear positioning") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of microtubule cytoskeleton-dependent nucleus positioning") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of microtubule-dependent nuclear positioning") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of microtubule-dependent nucleus positioning") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of microtubule-mediated nuclear migration") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of nuclear migration, microtubule-mediated") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of transport of nucleus by microtubules") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of transport of nucleus, microtubule-mediated") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of microtubule cytoskeleton-dependent nuclear positioning") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of microtubule cytoskeleton-dependent nucleus positioning") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of microtubule-dependent nuclear positioning") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of microtubule-dependent nucleus positioning") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of microtubule-mediated nuclear migration") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of nuclear migration along microtubule") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of nuclear migration, microtubule-mediated") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of transport of nucleus by microtubules") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of transport of nucleus, microtubule-mediated") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of microtubule cytoskeleton-dependent nuclear positioning") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of microtubule cytoskeleton-dependent nucleus positioning") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of microtubule-dependent nuclear positioning") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of microtubule-dependent nucleus positioning") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of microtubule-mediated nuclear migration") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of nuclear migration along microtubule") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of nuclear migration, microtubule-mediated") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of transport of nucleus by microtubules") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of transport of nucleus, microtubule-mediated") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of microtubule cytoskeleton-dependent nuclear positioning") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of microtubule cytoskeleton-dependent nucleus positioning") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of microtubule-dependent nuclear positioning") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of microtubule-dependent nucleus positioning") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of microtubule-mediated nuclear migration") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of nuclear migration along microtubule") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of nuclear migration, microtubule-mediated") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of transport of nucleus by microtubules") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of transport of nucleus, microtubule-mediated") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of microtubule cytoskeleton-dependent nuclear positioning") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of microtubule cytoskeleton-dependent nucleus positioning") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of microtubule-dependent nuclear positioning") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of microtubule-dependent nucleus positioning") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of microtubule-mediated nuclear migration") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of nuclear migration along microtubule") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of nuclear migration, microtubule-mediated") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of transport of nucleus by microtubules") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of transport of nucleus, microtubule-mediated") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902840") -AnnotationAssertion(rdfs:label "positive regulation of nuclear migration along microtubule") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (microtubule cytoskeleton organization involved in mitosis) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000060") Annotation( "PMID:18799626") "Any microtubule cytoskeleton organization that is involved in mitosis.") -AnnotationAssertion( "vw") -AnnotationAssertion( "2014-04-02T14:19:38Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "microtubule cytoskeleton organisation involved in mitosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "microtubule dynamics involved in mitosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "microtubule cytoskeleton organization and biogenesis involved in mitosis") -AnnotationAssertion( "GO:1902850") -AnnotationAssertion(rdfs:label "microtubule cytoskeleton organization involved in mitosis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of non-motile cilium assembly) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:cilia") Annotation( "GOC:kmv") Annotation( "GO_REF:0000058") Annotation( "PMID:23807208") "Any process that modulates the frequency, rate or extent of non-motile cilium assembly.") -AnnotationAssertion( "kmv") -AnnotationAssertion( "2014-04-02T15:41:57Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of immotile primary cilium assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of nonmotile primary cilia assembly") -AnnotationAssertion( "regulation of nonmotile primary cilium assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of sensory cilium assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of sensory cilium biogenesis") -AnnotationAssertion( "GO:1902855") -AnnotationAssertion(rdfs:label "regulation of non-motile cilium assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of non-motile cilium assembly) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:cilia") Annotation( "GOC:kmv") Annotation( "GO_REF:0000058") Annotation( "PMID:23807208") "Any process that stops, prevents or reduces the frequency, rate or extent of non-motile cilium assembly.") -AnnotationAssertion( "kmv") -AnnotationAssertion( "2014-04-02T15:42:17Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of immotile primary cilium assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of nonmotile primary cilium assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of sensory cilium assembly") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of immotile primary cilium assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of nonmotile primary cilia assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of nonmotile primary cilium assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of sensory cilium assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of sensory cilium biogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of immotile primary cilium assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of nonmotile primary cilia assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of nonmotile primary cilium assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of sensory cilium assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of sensory cilium biogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of immotile primary cilium assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of nonmotile primary cilia assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of nonmotile primary cilium assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of sensory cilium assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of sensory cilium biogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of nonmotile primary cilia assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of sensory cilium biogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of immotile primary cilium assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of nonmotile primary cilia assembly") -AnnotationAssertion( "negative regulation of nonmotile primary cilium assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of sensory cilium assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of sensory cilium biogenesis") -AnnotationAssertion( "GO:1902856") -AnnotationAssertion(rdfs:label "negative regulation of non-motile cilium assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of non-motile cilium assembly) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:cilia") Annotation( "GOC:kmv") Annotation( "GO_REF:0000058") Annotation( "PMID:23807208") "Any process that activates or increases the frequency, rate or extent of non-motile cilium assembly.") -AnnotationAssertion( "kmv") -AnnotationAssertion( "2014-04-02T15:42:31Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of immotile primary cilium assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of nonmotile primary cilium assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of sensory cilium assembly") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of nonmotile primary cilia assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of sensory cilium biogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of immotile primary cilium assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of nonmotile primary cilia assembly") -AnnotationAssertion( "positive regulation of nonmotile primary cilium assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of sensory cilium assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of sensory cilium biogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of immotile primary cilium assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of nonmotile primary cilia assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of nonmotile primary cilium assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of sensory cilium assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of sensory cilium biogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of immotile primary cilium assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of nonmotile primary cilia assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of nonmotile primary cilium assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of sensory cilium assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of sensory cilium biogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of immotile primary cilium assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of nonmotile primary cilia assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of nonmotile primary cilium assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of sensory cilium assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of sensory cilium biogenesis") -AnnotationAssertion( "GO:1902857") -AnnotationAssertion(rdfs:label "positive regulation of non-motile cilium assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of embryonic camera-type eye development) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mr") Annotation( "GO_REF:0000058") Annotation( "PMID:16872597") "Any process that modulates the frequency, rate or extent of embryonic camera-type eye development.") -AnnotationAssertion( "mr") -AnnotationAssertion( "2014-04-03T15:24:00Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of embryonic eye development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902863") -AnnotationAssertion(rdfs:label "regulation of embryonic camera-type eye development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of embryonic camera-type eye development) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mr") Annotation( "GO_REF:0000058") Annotation( "PMID:16872597") "Any process that stops, prevents or reduces the frequency, rate or extent of embryonic camera-type eye development.") -AnnotationAssertion( "mr") -AnnotationAssertion( "2014-04-03T15:24:06Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of embryonic camera-type eye development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of embryonic eye development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of embryonic camera-type eye development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of embryonic eye development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of embryonic camera-type eye development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of embryonic eye development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of embryonic eye development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of embryonic camera-type eye development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of embryonic eye development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902864") -AnnotationAssertion(rdfs:label "negative regulation of embryonic camera-type eye development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of embryonic camera-type eye development) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mr") Annotation( "GO_REF:0000058") Annotation( "PMID:16872597") "Any process that activates or increases the frequency, rate or extent of embryonic camera-type eye development.") -AnnotationAssertion( "mr") -AnnotationAssertion( "2014-04-03T15:24:12Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of embryonic eye development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of embryonic camera-type eye development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of embryonic eye development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of embryonic camera-type eye development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of embryonic eye development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of embryonic camera-type eye development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of embryonic eye development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of embryonic camera-type eye development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of embryonic eye development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902865") -AnnotationAssertion(rdfs:label "positive regulation of embryonic camera-type eye development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of retina development in camera-type eye) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mr") Annotation( "GO_REF:0000058") Annotation( "PMID:16872597") "Any process that modulates the frequency, rate or extent of retina development in camera-type eye.") -AnnotationAssertion( "mr") -AnnotationAssertion( "2014-04-03T15:24:17Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of retina development in camera-style eye") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of retinal development") -AnnotationAssertion( "GO:1902866") -AnnotationAssertion(rdfs:label "regulation of retina development in camera-type eye") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of retina development in camera-type eye) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mr") Annotation( "GO_REF:0000058") Annotation( "PMID:16872597") "Any process that stops, prevents or reduces the frequency, rate or extent of retina development in camera-type eye.") -AnnotationAssertion( "mr") -AnnotationAssertion( "2014-04-03T15:24:23Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of retina development in camera-style eye") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of retina development in camera-type eye") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of retina development in camera-style eye") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of retina development in camera-type eye") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of retina development in camera-style eye") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of retina development in camera-type eye") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of retina development in camera-style eye") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of retina development in camera-style eye") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of retina development in camera-type eye") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of retinal development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of retinal development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of retinal development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of retinal development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of retinal development") -AnnotationAssertion( "GO:1902867") -AnnotationAssertion(rdfs:label "negative regulation of retina development in camera-type eye") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of retina development in camera-type eye) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mr") Annotation( "GO_REF:0000058") Annotation( "PMID:16872597") "Any process that activates or increases the frequency, rate or extent of retina development in camera-type eye.") -AnnotationAssertion( "mr") -AnnotationAssertion( "2014-04-03T15:24:29Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of retina development in camera-style eye") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of retina development in camera-style eye") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of retina development in camera-type eye") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of retina development in camera-style eye") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of retina development in camera-type eye") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of retina development in camera-style eye") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of retina development in camera-type eye") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of retina development in camera-style eye") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of retina development in camera-type eye") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of retinal development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of retinal development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of retinal development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of retinal development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of retinal development") -AnnotationAssertion( "GO:1902868") -AnnotationAssertion(rdfs:label "positive regulation of retina development in camera-type eye") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (regulation of amacrine cell differentiation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mr") Annotation( "GO_REF:0000058") Annotation( "PMID:16872597") "Any process that modulates the frequency, rate or extent of amacrine cell differentiation.") -AnnotationAssertion( "mr") -AnnotationAssertion( "2014-04-03T15:24:35Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of amacrine neuron differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902869") -AnnotationAssertion(rdfs:label "regulation of amacrine cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of amacrine cell differentiation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mr") Annotation( "GO_REF:0000058") Annotation( "PMID:16872597") "Any process that stops, prevents or reduces the frequency, rate or extent of amacrine cell differentiation.") -AnnotationAssertion( "mr") -AnnotationAssertion( "2014-04-03T15:24:40Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of amacrine cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of amacrine neuron differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of amacrine cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of amacrine neuron differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of amacrine cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of amacrine neuron differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of amacrine neuron differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of amacrine cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of amacrine neuron differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902870") -AnnotationAssertion(rdfs:label "negative regulation of amacrine cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of amacrine cell differentiation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mr") Annotation( "GO_REF:0000058") Annotation( "PMID:16872597") "Any process that activates or increases the frequency, rate or extent of amacrine cell differentiation.") -AnnotationAssertion( "mr") -AnnotationAssertion( "2014-04-03T15:24:46Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of amacrine neuron differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of amacrine cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of amacrine neuron differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of amacrine cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of amacrine neuron differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of amacrine cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of amacrine neuron differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of amacrine cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of amacrine neuron differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902871") -AnnotationAssertion(rdfs:label "positive regulation of amacrine cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of embryonic pattern specification) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mr") Annotation( "GO_REF:0000058") Annotation( "PMID:16872597") "Any process that modulates the frequency, rate or extent of embryonic pattern specification.") -AnnotationAssertion( "mr") -AnnotationAssertion( "2014-04-03T15:25:15Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of embryonic pattern biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of embryonic pattern formation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of ventral/lateral system") -AnnotationAssertion( "GO:1902875") -AnnotationAssertion(rdfs:label "regulation of embryonic pattern specification") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of embryonic pattern specification) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mr") Annotation( "GO_REF:0000058") Annotation( "PMID:16872597") "Any process that stops, prevents or reduces the frequency, rate or extent of embryonic pattern specification.") -AnnotationAssertion( "mr") -AnnotationAssertion( "2014-04-03T15:25:20Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of embryonic pattern specification") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of embryonic pattern specification") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of embryonic pattern specification") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of embryonic pattern specification") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of ventral/lateral system") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of ventral/lateral system") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of ventral/lateral system") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of ventral/lateral system") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of ventral/lateral system") -AnnotationAssertion( "GO:1902876") -AnnotationAssertion(rdfs:label "negative regulation of embryonic pattern specification") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of embryonic pattern specification) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mr") Annotation( "GO_REF:0000058") Annotation( "PMID:16872597") "Any process that activates or increases the frequency, rate or extent of embryonic pattern specification.") -AnnotationAssertion( "mr") -AnnotationAssertion( "2014-04-03T15:25:26Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of embryonic pattern specification") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of embryonic pattern specification") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of embryonic pattern specification") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of embryonic pattern specification") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of ventral/lateral system") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of ventral/lateral system") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of ventral/lateral system") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of ventral/lateral system") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of ventral/lateral system") -AnnotationAssertion( "GO:1902877") -AnnotationAssertion(rdfs:label "positive regulation of embryonic pattern specification") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of supramolecular fiber organization) - -AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "GO_REF:0000058") Annotation( "PMID:23921388") "Any process that modulates the frequency, rate or extent of supramolecular fiber organization.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2014-04-15T16:46:36Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of fibril organisation") -AnnotationAssertion( "GO:1902903") -AnnotationAssertion(rdfs:comment "HSPA8, human, P11142 in PMID:23921388 inferred from direct assay to negatively regulate fibrillation of alpha-Syn in vitro") -AnnotationAssertion(rdfs:label "regulation of supramolecular fiber organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of supramolecular fiber organization) - -AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "GO_REF:0000058") Annotation( "PMID:23921388") "Any process that stops, prevents or reduces the frequency, rate or extent of fibril organization.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2014-04-15T16:46:42Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of fibril organisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of fibril organization") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of fibril organisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of fibril organization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of fibril organisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of fibril organization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of fibril organisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of fibril organization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of fibril organisation") -AnnotationAssertion( "GO:1902904") -AnnotationAssertion(rdfs:comment "HSPA8, human, P11142 in PMID:23921388 inferred from direct assay to negatively regulate fibrillation of alpha-Syn in vitro") -AnnotationAssertion(rdfs:label "negative regulation of supramolecular fiber organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of supramolecular fiber organization) - -AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "GO_REF:0000058") Annotation( "PMID:23921388") "Any process that activates or increases the frequency, rate or extent of supramolecular fiber organization.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2014-04-15T16:46:48Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of fibril organisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of fibril organization") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of fibril organisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of fibril organisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of fibril organization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of fibril organisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of fibril organization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of fibril organisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of fibril organization") -AnnotationAssertion( "GO:1902905") -AnnotationAssertion(rdfs:comment "HSPA8, human, P11142 in PMID:23921388 inferred from direct assay to negatively regulate fibrillation of alpha-Syn in vitro") -AnnotationAssertion(rdfs:label "positive regulation of supramolecular fiber organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of melanosome transport) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:als") Annotation( "GO_REF:0000058") Annotation( "PMID:23334344") "Any process that modulates the frequency, rate or extent of melanosome transport.") -AnnotationAssertion( "als") -AnnotationAssertion( "2014-04-17T11:40:16Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902908") -AnnotationAssertion(rdfs:label "regulation of melanosome transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (negative regulation of melanosome transport) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:als") Annotation( "GO_REF:0000058") Annotation( "PMID:23334344") "Any process that stops, prevents or reduces the frequency, rate or extent of melanosome transport.") -AnnotationAssertion( "als") -AnnotationAssertion( "2014-04-17T11:40:28Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of melanosome transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of melanosome transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of melanosome transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of melanosome transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902909") -AnnotationAssertion(rdfs:label "negative regulation of melanosome transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of melanosome transport) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:als") Annotation( "GO_REF:0000058") Annotation( "PMID:23334344") "Any process that activates or increases the frequency, rate or extent of melanosome transport.") -AnnotationAssertion( "als") -AnnotationAssertion( "2014-04-17T11:40:34Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of melanosome transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of melanosome transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of melanosome transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of melanosome transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902910") -AnnotationAssertion(rdfs:label "positive regulation of melanosome transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (protein kinase complex) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:bhm") Annotation( "GO_REF:0000088") Annotation( "PMID:24606918") "A protein complex which is capable of protein kinase activity.") -AnnotationAssertion( "bhm") -AnnotationAssertion( "2014-04-17T13:52:40Z") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:1902911") -AnnotationAssertion(rdfs:comment "An example of this is PKM2 in human (P14618) in PMID:24606918 (inferred from direct assay).") -AnnotationAssertion(rdfs:label "protein kinase complex") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of neuroepithelial cell differentiation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mr") Annotation( "GO_REF:0000058") Annotation( "PMID:16916506") "Any process that activates or increases the frequency, rate or extent of neuroepithelial cell differentiation.") -AnnotationAssertion( "mr") -AnnotationAssertion( "2014-04-18T21:06:42Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of neuroepithelial cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of neuroepithelial cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of neuroepithelial cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of neuroepithelial cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902913") -AnnotationAssertion(rdfs:label "positive regulation of neuroepithelial cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of alcohol biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mengo_curators") Annotation( "GO_REF:0000058") Annotation( "PMID:23332010") "Any process that modulates the frequency, rate or extent of alcohol biosynthetic process.") -AnnotationAssertion( "tt") -AnnotationAssertion( "2014-04-22T21:55:03Z") -AnnotationAssertion( "regulation of solventogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of alcohol anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of alcohol biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of alcohol formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of alcohol synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902930") -AnnotationAssertion(rdfs:label "regulation of alcohol biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of alcohol biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mengo_curators") Annotation( "GO_REF:0000058") Annotation( "PMID:23332010") "Any process that stops, prevents or reduces the frequency, rate or extent of alcohol biosynthetic process.") -AnnotationAssertion( "tt") -AnnotationAssertion( "2014-04-22T21:55:13Z") -AnnotationAssertion( "negative regulation of solventogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of alcohol anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of alcohol biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of alcohol biosynthetic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of alcohol formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of alcohol synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of alcohol anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of alcohol biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of alcohol biosynthetic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of alcohol formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of alcohol synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of alcohol anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of alcohol biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of alcohol biosynthetic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of alcohol formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of alcohol synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of alcohol anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of alcohol biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of alcohol formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of alcohol synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of alcohol anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of alcohol biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of alcohol biosynthetic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of alcohol formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of alcohol synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902931") -AnnotationAssertion(rdfs:label "negative regulation of alcohol biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of alcohol biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mengo_curators") Annotation( "GO_REF:0000058") Annotation( "PMID:23332010") "Any process that activates or increases the frequency, rate or extent of alcohol biosynthetic process.") -AnnotationAssertion( "tt") -AnnotationAssertion( "2014-04-22T21:55:19Z") -AnnotationAssertion( "positive regulation of solventogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of alcohol anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of alcohol biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of alcohol formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of alcohol synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of alcohol anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of alcohol biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of alcohol biosynthetic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of alcohol formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of alcohol synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of alcohol anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of alcohol biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of alcohol biosynthetic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of alcohol formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of alcohol synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of alcohol anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of alcohol biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of alcohol biosynthetic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of alcohol formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of alcohol synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of alcohol anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of alcohol biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of alcohol biosynthetic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of alcohol formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of alcohol synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1902932") -AnnotationAssertion(rdfs:label "positive regulation of alcohol biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of lipid transport across blood-brain barrier) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:sjp") Annotation( "GO_REF:0000058") Annotation( "PMID:24345162") "Any process that modulates the frequency, rate or extent of lipid transport across blood-brain barrier.") -AnnotationAssertion( "sjp") -AnnotationAssertion( "2014-05-09T09:30:04Z") -AnnotationAssertion( "regulation of lipid transport across blood brain barrier") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903000") -AnnotationAssertion(rdfs:label "regulation of lipid transport across blood-brain barrier") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - -# Class: (negative regulation of lipid transport across blood-brain barrier) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:sjp") Annotation( "GO_REF:0000058") Annotation( "PMID:24345162") "Any process that stops, prevents or reduces the frequency, rate or extent of lipid transport across blood-brain barrier.") -AnnotationAssertion( "sjp") -AnnotationAssertion( "2014-05-09T09:30:10Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of lipid transport across blood brain barrier") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of lipid transport across blood brain barrier") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of lipid transport across blood brain barrier") -AnnotationAssertion( "negative regulation of lipid transport across blood brain barrier") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of lipid transport across blood brain barrier") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903001") -AnnotationAssertion(rdfs:label "negative regulation of lipid transport across blood-brain barrier") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of lipid transport across blood-brain barrier) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:sjp") Annotation( "GO_REF:0000058") Annotation( "PMID:24345162") "Any process that activates or increases the frequency, rate or extent of lipid transport across blood-brain barrier.") -AnnotationAssertion( "sjp") -AnnotationAssertion( "2014-05-09T09:30:16Z") -AnnotationAssertion( "positive regulation of lipid transport across blood brain barrier") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of lipid transport across blood brain barrier") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of lipid transport across blood brain barrier") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of lipid transport across blood brain barrier") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of lipid transport across blood brain barrier") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903002") -AnnotationAssertion(rdfs:label "positive regulation of lipid transport across blood-brain barrier") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (organelle disassembly) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000079") "The disaggregation of an organelle into its constituent components.") -AnnotationAssertion( "jl") -AnnotationAssertion( "2014-05-13T12:36:03Z") -AnnotationAssertion( "organelle degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903008") -AnnotationAssertion(rdfs:label "organelle disassembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of bone development) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mr") Annotation( "GO_REF:0000058") Annotation( "PMID:22510437") "Any process that modulates the frequency, rate or extent of bone development.") -AnnotationAssertion( "mr") -AnnotationAssertion( "2014-05-13T22:41:53Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903010") -AnnotationAssertion(rdfs:label "regulation of bone development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (negative regulation of bone development) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mr") Annotation( "GO_REF:0000058") Annotation( "PMID:22510437") "Any process that stops, prevents or reduces the frequency, rate or extent of bone development.") -AnnotationAssertion( "mr") -AnnotationAssertion( "2014-05-13T22:42:00Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of bone development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of bone development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of bone development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of bone development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903011") -AnnotationAssertion(rdfs:label "negative regulation of bone development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of bone development) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mr") Annotation( "GO_REF:0000058") Annotation( "PMID:22510437") "Any process that activates or increases the frequency, rate or extent of bone development.") -AnnotationAssertion( "mr") -AnnotationAssertion( "2014-05-13T22:42:06Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of bone development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of bone development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of bone development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of bone development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903012") -AnnotationAssertion(rdfs:label "positive regulation of bone development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of glycoprotein metabolic process) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "GO_REF:0000058") Annotation( "PMID:23544079") "Any process that modulates the frequency, rate or extent of glycoprotein metabolic process.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2014-05-14T18:44:19Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of glycoprotein metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903018") -AnnotationAssertion(rdfs:comment "human serum amyloid P component (SAP) P02743 inhibits viral neuraminidase, NA (exo-alpha-sialidase activity) and thus the metabolism of glycoproteins, demonstrated in Figure 4A PMID:23544079, (IDA), the negative regulation term would be applied to this protein") -AnnotationAssertion(rdfs:label "regulation of glycoprotein metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of glycoprotein metabolic process) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "GO_REF:0000058") Annotation( "PMID:23544079") "Any process that stops, prevents or reduces the frequency, rate or extent of glycoprotein metabolic process.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2014-05-14T18:44:25Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of glycoprotein metabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of glycoprotein metabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of glycoprotein metabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of glycoprotein metabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of glycoprotein metabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of glycoprotein metabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of glycoprotein metabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of glycoprotein metabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of glycoprotein metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903019") -AnnotationAssertion(rdfs:comment "human serum amyloid P component (SAP) P02743 inhibits viral neuraminidase, NA (exo-alpha-sialidase activity) and thus the metabolism of glycoproteins, demonstrated in Figure 4A PMID:23544079, (IDA), the negative regulation term would be applied to this protein") -AnnotationAssertion(rdfs:label "negative regulation of glycoprotein metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of glycoprotein metabolic process) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "GO_REF:0000058") Annotation( "PMID:23544079") "Any process that activates or increases the frequency, rate or extent of glycoprotein metabolic process.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2014-05-14T18:44:31Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of glycoprotein metabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of glycoprotein metabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of glycoprotein metabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of glycoprotein metabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of glycoprotein metabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of glycoprotein metabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of glycoprotein metabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of glycoprotein metabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of glycoprotein metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903020") -AnnotationAssertion(rdfs:comment "human serum amyloid P component (SAP) P02743 inhibits viral neuraminidase, NA (exo-alpha-sialidase activity) and thus the metabolism of glycoproteins, demonstrated in Figure 4A PMID:23544079, (IDA), the negative regulation term would be applied to this protein") -AnnotationAssertion(rdfs:label "positive regulation of glycoprotein metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of response to wounding) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:kmv") Annotation( "GO_REF:0000058") Annotation( "PMID:19164535") "Any process that modulates the frequency, rate or extent of response to wounding.") -AnnotationAssertion( "kmv") -AnnotationAssertion( "2014-05-18T01:28:46Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of physiological response to wounding") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903034") -AnnotationAssertion(rdfs:label "regulation of response to wounding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (negative regulation of response to wounding) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:kmv") Annotation( "GO_REF:0000058") Annotation( "PMID:19164535") "Any process that stops, prevents or reduces the frequency, rate or extent of response to wounding.") -AnnotationAssertion( "kmv") -AnnotationAssertion( "2014-05-18T01:28:52Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of physiological response to wounding") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of response to wounding") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of physiological response to wounding") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of response to wounding") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of physiological response to wounding") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of response to wounding") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of physiological response to wounding") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of physiological response to wounding") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of response to wounding") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903035") -AnnotationAssertion(rdfs:label "negative regulation of response to wounding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of response to wounding) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:kmv") Annotation( "GO_REF:0000058") Annotation( "PMID:19164535") "Any process that activates or increases the frequency, rate or extent of response to wounding.") -AnnotationAssertion( "kmv") -AnnotationAssertion( "2014-05-18T01:28:58Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of physiological response to wounding") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of physiological response to wounding") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of response to wounding") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of physiological response to wounding") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of response to wounding") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of physiological response to wounding") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of response to wounding") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of physiological response to wounding") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of response to wounding") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903036") -AnnotationAssertion(rdfs:label "positive regulation of response to wounding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of leukocyte cell-cell adhesion) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "GO_REF:0000058") Annotation( "PMID:21106532") "Any process that modulates the frequency, rate or extent of leukocyte cell-cell adhesion.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2014-05-19T15:29:58Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of leukocyte adhesion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of leukocyte cell adhesion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903037") -AnnotationAssertion(rdfs:comment "Exogenous expression of ASS1 or NOS3 in HUVECs enhances NO production and inhibits monocyte adhesion") -AnnotationAssertion(rdfs:label "regulation of leukocyte cell-cell adhesion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (negative regulation of leukocyte cell-cell adhesion) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "GO_REF:0000058") Annotation( "PMID:21106532") "Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte cell-cell adhesion.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2014-05-19T15:30:05Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of leukocyte adhesion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of leukocyte cell adhesion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of leukocyte cell-cell adhesion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of leukocyte adhesion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of leukocyte cell adhesion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of leukocyte cell-cell adhesion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of leukocyte adhesion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of leukocyte cell adhesion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of leukocyte cell-cell adhesion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of leukocyte adhesion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of leukocyte cell adhesion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of leukocyte adhesion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of leukocyte cell adhesion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of leukocyte cell-cell adhesion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903038") -AnnotationAssertion(rdfs:comment "Exogenous expression of ASS1 or NOS3 in HUVECs enhances NO production and inhibits monocyte adhesion") -AnnotationAssertion(rdfs:label "negative regulation of leukocyte cell-cell adhesion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of leukocyte cell-cell adhesion) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "GO_REF:0000058") Annotation( "PMID:21106532") "Any process that activates or increases the frequency, rate or extent of leukocyte cell-cell adhesion.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2014-05-19T15:30:15Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of leukocyte adhesion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of leukocyte cell adhesion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of leukocyte adhesion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of leukocyte cell adhesion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of leukocyte cell-cell adhesion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of leukocyte adhesion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of leukocyte cell adhesion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of leukocyte cell-cell adhesion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of leukocyte adhesion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of leukocyte cell adhesion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of leukocyte cell-cell adhesion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of leukocyte adhesion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of leukocyte cell adhesion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of leukocyte cell-cell adhesion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903039") -AnnotationAssertion(rdfs:comment "Exogenous expression of ASS1 or NOS3 in HUVECs enhances NO production and inhibits monocyte adhesion") -AnnotationAssertion(rdfs:label "positive regulation of leukocyte cell-cell adhesion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of chondrocyte hypertrophy) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mr") Annotation( "GO_REF:0000058") Annotation( "PMID:23928032") "Any process that modulates the frequency, rate or extent of chondrocyte hypertrophy.") -AnnotationAssertion( "mr") -AnnotationAssertion( "2014-05-20T21:23:13Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903041") -AnnotationAssertion(rdfs:label "regulation of chondrocyte hypertrophy") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of chondrocyte hypertrophy) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mr") Annotation( "GO_REF:0000058") Annotation( "PMID:23928032") "Any process that stops, prevents or reduces the frequency, rate or extent of chondrocyte hypertrophy.") -AnnotationAssertion( "mr") -AnnotationAssertion( "2014-05-20T21:23:19Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of chondrocyte hypertrophy") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of chondrocyte hypertrophy") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of chondrocyte hypertrophy") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of chondrocyte hypertrophy") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903042") -AnnotationAssertion(rdfs:label "negative regulation of chondrocyte hypertrophy") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of chondrocyte hypertrophy) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mr") Annotation( "GO_REF:0000058") Annotation( "PMID:23928032") "Any process that activates or increases the frequency, rate or extent of chondrocyte hypertrophy.") -AnnotationAssertion( "mr") -AnnotationAssertion( "2014-05-20T21:23:25Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of chondrocyte hypertrophy") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of chondrocyte hypertrophy") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of chondrocyte hypertrophy") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of chondrocyte hypertrophy") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903043") -AnnotationAssertion(rdfs:label "positive regulation of chondrocyte hypertrophy") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (neural crest cell migration involved in sympathetic nervous system development) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "GO_REF:0000060") Annotation( "PMID:19325129") "Any neural crest cell migration that is involved in sympathetic nervous system development.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2014-05-22T07:06:02Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903045") -AnnotationAssertion(rdfs:comment "Sema3a (O08665, mouse) is involved in neural crest cell migration involved in sympathetic nervous system development") -AnnotationAssertion(rdfs:label "neural crest cell migration involved in sympathetic nervous system development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (meiotic cell cycle process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mtg_cell_cycle") Annotation( "GO_REF:0000060") "A process that is part of the meiotic cell cycle.") -AnnotationAssertion( "jl") -AnnotationAssertion( "2014-05-22T14:22:28Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903046") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "meiotic cell cycle process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -DisjointClasses( ) - -# Class: (mitotic cell cycle process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mtg_cell_cycle") Annotation( "GO_REF:0000060") "A process that is part of the mitotic cell cycle.") -AnnotationAssertion( "jl") -AnnotationAssertion( "2014-05-22T14:22:34Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903047") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "mitotic cell cycle process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of proteolysis involved in protein catabolic process) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "GO_REF:0000058") Annotation( "PMID:18307834") "Any process that modulates the frequency, rate or extent of proteolysis involved in cellular catabolic process.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/23112"^^xsd:anyURI) -AnnotationAssertion( "rl") -AnnotationAssertion( "2014-05-22T18:00:45Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of peptidolysis involved in cellular protein catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of peptidolysis involved in cellular protein catabolism") -AnnotationAssertion( "regulation of proteolysis involved in cellular protein catabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of peptidolysis during cellular protein catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of peptidolysis during cellular protein catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of proteolysis during cellular protein catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of proteolysis during cellular protein catabolism") -AnnotationAssertion( "GO:1903050") -AnnotationAssertion(rdfs:comment "overexpression of cathepsin C propeptide significantly increased the degradation of intestinal alkaline phosphatase (IAP)") -AnnotationAssertion(rdfs:label "regulation of proteolysis involved in protein catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of proteolysis involved in protein catabolic process) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "GO_REF:0000058") Annotation( "PMID:18307834") "Any process that stops, prevents or reduces the frequency, rate or extent of proteolysis involved in protein catabolic process.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/23112"^^xsd:anyURI) -AnnotationAssertion( "rl") -AnnotationAssertion( "2014-05-22T18:00:51Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of peptidolysis involved in cellular protein catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of peptidolysis involved in cellular protein catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of proteolysis involved in cellular protein catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of peptidolysis involved in cellular protein catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of peptidolysis involved in cellular protein catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of proteolysis involved in cellular protein catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of peptidolysis involved in cellular protein catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of peptidolysis involved in cellular protein catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of proteolysis involved in cellular protein catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of peptidolysis involved in cellular protein catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of peptidolysis involved in cellular protein catabolism") -AnnotationAssertion( "negative regulation of proteolysis involved in cellular protein catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of peptidolysis involved in cellular protein catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of peptidolysis involved in cellular protein catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of proteolysis involved in cellular protein catabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of peptidolysis during cellular protein catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of peptidolysis during cellular protein catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of proteolysis during cellular protein catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of proteolysis during cellular protein catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of peptidolysis during cellular protein catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of peptidolysis during cellular protein catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of proteolysis during cellular protein catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of proteolysis during cellular protein catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of peptidolysis during cellular protein catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of peptidolysis during cellular protein catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of proteolysis during cellular protein catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of proteolysis during cellular protein catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of peptidolysis during cellular protein catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of peptidolysis during cellular protein catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of proteolysis during cellular protein catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of proteolysis during cellular protein catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of peptidolysis during cellular protein catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of peptidolysis during cellular protein catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of proteolysis during cellular protein catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of proteolysis during cellular protein catabolism") -AnnotationAssertion( "GO:1903051") -AnnotationAssertion(rdfs:comment "Overexpression of cathepsin C propeptide significantly increased the degradation of intestinal alkaline phosphatase (IAP).") -AnnotationAssertion(rdfs:label "negative regulation of proteolysis involved in protein catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of proteolysis involved in protein catabolic process) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "GO_REF:0000058") Annotation( "PMID:18307834") "Any process that activates or increases the frequency, rate or extent of proteolysis involved in protein catabolic process.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/23112"^^xsd:anyURI) -AnnotationAssertion( "rl") -AnnotationAssertion( "2014-05-22T18:00:57Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of peptidolysis involved in cellular protein catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of peptidolysis involved in cellular protein catabolism") -AnnotationAssertion( "positive regulation of proteolysis involved in cellular protein catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of peptidolysis involved in cellular protein catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of peptidolysis involved in cellular protein catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of proteolysis involved in cellular protein catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of peptidolysis involved in cellular protein catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of peptidolysis involved in cellular protein catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of proteolysis involved in cellular protein catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of peptidolysis involved in cellular protein catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of peptidolysis involved in cellular protein catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of proteolysis involved in cellular protein catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of peptidolysis involved in cellular protein catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of peptidolysis involved in cellular protein catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of proteolysis involved in cellular protein catabolic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of peptidolysis during cellular protein catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of peptidolysis during cellular protein catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of proteolysis during cellular protein catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of proteolysis during cellular protein catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of peptidolysis during cellular protein catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of peptidolysis during cellular protein catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of proteolysis during cellular protein catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of proteolysis during cellular protein catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of peptidolysis during cellular protein catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of peptidolysis during cellular protein catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of proteolysis during cellular protein catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of proteolysis during cellular protein catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of peptidolysis during cellular protein catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of peptidolysis during cellular protein catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of proteolysis during cellular protein catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of proteolysis during cellular protein catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of peptidolysis during cellular protein catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of peptidolysis during cellular protein catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of proteolysis during cellular protein catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of proteolysis during cellular protein catabolism") -AnnotationAssertion( "GO:1903052") -AnnotationAssertion(rdfs:comment "overexpression of cathepsin C propeptide significantly increased the degradation of intestinal alkaline phosphatase (IAP)") -AnnotationAssertion(rdfs:label "positive regulation of proteolysis involved in protein catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of extracellular matrix organization) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "GO_REF:0000058") Annotation( "PMID:22357537") "Any process that modulates the frequency, rate or extent of extracellular matrix organization.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2014-05-23T17:15:41Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of extracellular matrix organisation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of extracellular matrix organization and biogenesis") -AnnotationAssertion( "GO:1903053") -AnnotationAssertion(rdfs:label "regulation of extracellular matrix organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (negative regulation of extracellular matrix organization) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "GO_REF:0000058") Annotation( "PMID:22357537") "Any process that stops, prevents or reduces the frequency, rate or extent of extracellular matrix organization.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2014-05-23T17:15:47Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of extracellular matrix organisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of extracellular matrix organization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of extracellular matrix organisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of extracellular matrix organization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of extracellular matrix organisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of extracellular matrix organization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of extracellular matrix organisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of extracellular matrix organisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of extracellular matrix organization") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of extracellular matrix organization and biogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of extracellular matrix organization and biogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of extracellular matrix organization and biogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of extracellular matrix organization and biogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of extracellular matrix organization and biogenesis") -AnnotationAssertion( "GO:1903054") -AnnotationAssertion(rdfs:label "negative regulation of extracellular matrix organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of extracellular matrix organization) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "GO_REF:0000058") Annotation( "PMID:22357537") "Any process that activates or increases the frequency, rate or extent of extracellular matrix organization.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2014-05-23T17:15:53Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of extracellular matrix organisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of extracellular matrix organisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of extracellular matrix organization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of extracellular matrix organisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of extracellular matrix organization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of extracellular matrix organisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of extracellular matrix organization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of extracellular matrix organisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of extracellular matrix organization") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of extracellular matrix organization and biogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of extracellular matrix organization and biogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of extracellular matrix organization and biogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of extracellular matrix organization and biogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of extracellular matrix organization and biogenesis") -AnnotationAssertion( "GO:1903055") -AnnotationAssertion(rdfs:label "positive regulation of extracellular matrix organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of melanosome organization) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "GO_REF:0000058") Annotation( "PMID:24769727") "Any process that modulates the frequency, rate or extent of melanosome organization.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2014-05-27T13:27:49Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of melanosome organisation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of melanosome organization and biogenesis") -AnnotationAssertion( "GO:1903056") -AnnotationAssertion(rdfs:comment "Lack of the transcription factor Zeb2 Q9R0G7 leads to spherical melanosomes with irregular borders, in contrast to the rod-shaped melanosomes of ZEB2MCWT hair follicles") -AnnotationAssertion(rdfs:label "regulation of melanosome organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of melanosome organization) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "GO_REF:0000058") Annotation( "PMID:24769727") "Any process that stops, prevents or reduces the frequency, rate or extent of melanosome organization.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2014-05-27T13:27:55Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of melanosome organisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of melanosome organization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of melanosome organisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of melanosome organization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of melanosome organisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of melanosome organization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of melanosome organisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of melanosome organisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of melanosome organization") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of melanosome organization and biogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of melanosome organization and biogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of melanosome organization and biogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of melanosome organization and biogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of melanosome organization and biogenesis") -AnnotationAssertion( "GO:1903057") -AnnotationAssertion(rdfs:comment "Lack of the transcription factor Zeb2 Q9R0G7 leads to spherical melanosomes with irregular borders, in contrast to the rod-shaped melanosomes of ZEB2MCWT hair follicles.") -AnnotationAssertion(rdfs:label "negative regulation of melanosome organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of melanosome organization) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "GO_REF:0000058") Annotation( "PMID:24769727") "Any process that activates or increases the frequency, rate or extent of melanosome organization.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2014-05-27T13:28:01Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of melanosome organisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of melanosome organisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of melanosome organization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of melanosome organisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of melanosome organization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of melanosome organisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of melanosome organization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of melanosome organisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of melanosome organization") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of melanosome organization and biogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of melanosome organization and biogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of melanosome organization and biogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of melanosome organization and biogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of melanosome organization and biogenesis") -AnnotationAssertion( "GO:1903058") -AnnotationAssertion(rdfs:comment "Lack of the transcription factor Zeb2 Q9R0G7 leads to spherical melanosomes with irregular borders, in contrast to the rod-shaped melanosomes of ZEB2MCWT hair follicles.") -AnnotationAssertion(rdfs:label "positive regulation of melanosome organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of protein localization to plasma membrane) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "GO_REF:0000058") Annotation( "PMID:11602640") "Any process that modulates the frequency, rate or extent of protein localization to plasma membrane.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2009-07-10T10:32:44Z") -AnnotationAssertion( "GO:0090003") -AnnotationAssertion( "GO:1905963") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of protein localization in plasma membrane") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:mah") "regulation of establishment of protein localisation in plasma membrane") -AnnotationAssertion( "regulation of establishment of protein localization in plasma membrane") -AnnotationAssertion( "regulation of establishment of protein localization to plasma membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of protein localisation in plasma membrane") -AnnotationAssertion( "regulation of protein targeting to plasma membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of protein-plasma membrane targeting") -AnnotationAssertion( "GO:1903076") -AnnotationAssertion(rdfs:label "regulation of protein localization to plasma membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of protein localization to plasma membrane) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "GO_REF:0000058") Annotation( "PMID:11602640") "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to plasma membrane.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2014-05-29T17:10:16Z") -AnnotationAssertion( "GO:0090005") -AnnotationAssertion( "GO:1905964") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of protein localisation in plasma membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of protein localization in plasma membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of protein localization to plasma membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of protein localisation in plasma membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of protein localization in plasma membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of protein localization to plasma membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of protein localisation in plasma membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of protein localization in plasma membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of protein localization to plasma membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of protein localization in plasma membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of protein localisation in plasma membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of protein localization in plasma membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of protein localization to plasma membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of protein targeting to plasma membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of protein-plasma membrane targeting") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of protein targeting to plasma membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of protein-plasma membrane targeting") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of protein targeting to plasma membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of protein-plasma membrane targeting") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of protein targeting to plasma membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of protein-plasma membrane targeting") -AnnotationAssertion(Annotation( "GOC:mah") "negative regulation of establishment of protein localisation in plasma membrane") -AnnotationAssertion( "negative regulation of establishment of protein localization in plasma membrane") -AnnotationAssertion( "negative regulation of establishment of protein localization to plasma membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of protein localisation in plasma membrane") -AnnotationAssertion( "negative regulation of protein targeting to plasma membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of protein-plasma membrane targeting") -AnnotationAssertion( "GO:1903077") -AnnotationAssertion(rdfs:label "negative regulation of protein localization to plasma membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of protein localization to plasma membrane) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "GO_REF:0000058") Annotation( "PMID:11602640") "Any process that activates or increases the frequency, rate or extent of protein localization to plasma membrane.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2009-07-10T10:34:17Z") -AnnotationAssertion( "GO:0090004") -AnnotationAssertion( "GO:1905965") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of protein localisation in plasma membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of protein localization in plasma membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of protein localisation in plasma membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of protein localization in plasma membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of protein localization to plasma membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of protein localisation in plasma membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of protein localization in plasma membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of protein localization to plasma membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of protein localisation in plasma membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of protein localization in plasma membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of protein localization to plasma membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of protein localisation in plasma membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of protein localization in plasma membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of protein localization to plasma membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of protein targeting to plasma membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of protein-plasma membrane targeting") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:mah") "positive regulation of establishment of protein localisation in plasma membrane") -AnnotationAssertion( "positive regulation of establishment of protein localization to plasma membrane") -AnnotationAssertion( "positive regulation of protein targeting to plasma membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of protein-plasma membrane targeting") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of protein targeting to plasma membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of protein-plasma membrane targeting") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of protein targeting to plasma membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of protein-plasma membrane targeting") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of protein targeting to plasma membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of protein-plasma membrane targeting") -AnnotationAssertion( "GO:1903078") -AnnotationAssertion(rdfs:label "positive regulation of protein localization to plasma membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of actin filament-based movement) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:24798735") "Any process that modulates the frequency, rate or extent of actin filament-based movement.") -AnnotationAssertion( "al") -AnnotationAssertion( "2014-06-12T16:55:57Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903115") -AnnotationAssertion(rdfs:label "regulation of actin filament-based movement") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of actin filament-based movement) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:24798735") "Any process that activates or increases the frequency, rate or extent of actin filament-based movement.") -AnnotationAssertion( "al") -AnnotationAssertion( "2014-06-12T16:56:04Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of actin filament-based movement") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of actin filament-based movement") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of actin filament-based movement") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of actin filament-based movement") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903116") -AnnotationAssertion(rdfs:label "positive regulation of actin filament-based movement") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (protein localization to actin cytoskeleton) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000087") Annotation( "PMID:24798735") "A process in which a protein is transported to, or maintained in, the location of an actin cytoskeleton.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2014-06-16T11:27:09Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "protein localisation in actin cytoskeleton") -AnnotationAssertion(Annotation( "GOC:TermGenie") "protein localisation to actin cytoskeleton") -AnnotationAssertion(Annotation( "GOC:TermGenie") "protein localization in actin cytoskeleton") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903119") -AnnotationAssertion(rdfs:label "protein localization to actin cytoskeleton") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (protein localization to actin filament bundle) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000087") Annotation( "PMID:24798735") "A process in which a protein is transported to, or maintained in, the location of an actin filament bundle.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2014-06-16T11:27:16Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "protein localisation in actin filament bundle") -AnnotationAssertion(Annotation( "GOC:TermGenie") "protein localisation to actin filament bundle") -AnnotationAssertion(Annotation( "GOC:TermGenie") "protein localization in actin filament bundle") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:mah") "protein localization to actin cable") -AnnotationAssertion( "GO:1903120") -AnnotationAssertion(rdfs:label "protein localization to actin filament bundle") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (mononuclear cell differentiation) - -AnnotationAssertion(Annotation( "CL:0000842") Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000086") Annotation( "PMID:24759906") "The process in which a relatively unspecialized cell acquires the specialized features of a mononuclear cell.") -AnnotationAssertion( "cls") -AnnotationAssertion( "2014-06-25T15:47:09Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903131") -AnnotationAssertion(rdfs:label "mononuclear cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of calcium ion transmembrane transport) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "GO_REF:0000058") Annotation( "PMID:24125847") "Any process that modulates the frequency, rate or extent of calcium ion transmembrane transport.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2014-07-11T17:09:26Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of calcium ion membrane transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of transmembrane calcium transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903169") -AnnotationAssertion(rdfs:comment "human HRC regulates RYR2 and thus regulates transmembrane transport of calcium from SR to cytosol") -AnnotationAssertion(rdfs:label "regulation of calcium ion transmembrane transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of calcium ion transmembrane transport) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "GO_REF:0000058") Annotation( "PMID:24125847") "Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion transmembrane transport.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2014-07-11T17:09:32Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of calcium ion membrane transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of calcium ion transmembrane transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of transmembrane calcium transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of calcium ion membrane transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of calcium ion transmembrane transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of transmembrane calcium transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of calcium ion membrane transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of calcium ion transmembrane transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of transmembrane calcium transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of calcium ion membrane transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of transmembrane calcium transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of calcium ion membrane transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of calcium ion transmembrane transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of transmembrane calcium transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903170") -AnnotationAssertion(rdfs:comment "human HRC regulates RYR2 and thus regulates transmembrane transport of calcium from SR to cytosol") -AnnotationAssertion(rdfs:label "negative regulation of calcium ion transmembrane transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of dopamine biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:TermGenie") Annotation( "GOC:bf") Annotation( "GO_REF:0000058") "Any process that modulates the frequency, rate or extent of dopamine biosynthetic process.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2014-07-14T12:17:41Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of dopamine anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of dopamine biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of dopamine formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of dopamine synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903179") -AnnotationAssertion(rdfs:label "regulation of dopamine biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of dopamine biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:TermGenie") Annotation( "GOC:bf") Annotation( "GO_REF:0000058") "Any process that stops, prevents or reduces the frequency, rate or extent of dopamine biosynthetic process.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2014-07-14T12:17:47Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of dopamine anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of dopamine biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of dopamine biosynthetic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of dopamine formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of dopamine synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of dopamine anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of dopamine biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of dopamine biosynthetic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of dopamine formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of dopamine synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of dopamine anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of dopamine biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of dopamine biosynthetic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of dopamine formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of dopamine synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of dopamine anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of dopamine biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of dopamine formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of dopamine synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of dopamine anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of dopamine biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of dopamine biosynthetic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of dopamine formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of dopamine synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903180") -AnnotationAssertion(rdfs:label "negative regulation of dopamine biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of dopamine biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:TermGenie") Annotation( "GOC:bf") Annotation( "GO_REF:0000058") Annotation( "PMID:19703902") "Any process that activates or increases the frequency, rate or extent of dopamine biosynthetic process.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2014-07-14T12:17:53Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of dopamine anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of dopamine biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of dopamine formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of dopamine synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of dopamine anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of dopamine biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of dopamine biosynthetic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of dopamine formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of dopamine synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of dopamine anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of dopamine biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of dopamine biosynthetic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of dopamine formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of dopamine synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of dopamine anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of dopamine biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of dopamine biosynthetic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of dopamine formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of dopamine synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of dopamine anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of dopamine biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of dopamine biosynthetic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of dopamine formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of dopamine synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903181") -AnnotationAssertion(rdfs:label "positive regulation of dopamine biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (podocyte apoptotic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000085") Annotation( "PMID:23515840") "Any apoptotic process in a glomerular visceral epithelial cell.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/23000"^^xsd:anyURI) -AnnotationAssertion( "sl") -AnnotationAssertion( "2014-07-23T17:07:55Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "glomerular podocyte apoptotic process") -AnnotationAssertion( "glomerular visceral epithelial cell apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "glomerular podocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "glomerular visceral epithelial cell apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "podocyte apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903210") -AnnotationAssertion(rdfs:label "podocyte apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of endodermal cell differentiation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:als") Annotation( "GO_REF:0000058") Annotation( "PMID:23154389") "Any process that modulates the frequency, rate or extent of endodermal cell differentiation.") -AnnotationAssertion( "als") -AnnotationAssertion( "2014-07-29T13:22:35Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of endoderm cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903224") -AnnotationAssertion(rdfs:label "regulation of endodermal cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of endodermal cell differentiation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:als") Annotation( "GO_REF:0000058") Annotation( "PMID:23154389") "Any process that stops, prevents or reduces the frequency, rate or extent of endodermal cell differentiation.") -AnnotationAssertion( "als") -AnnotationAssertion( "2014-07-29T13:22:41Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of endoderm cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of endodermal cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of endoderm cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of endodermal cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of endoderm cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of endodermal cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of endoderm cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of endoderm cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of endodermal cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903225") -AnnotationAssertion(rdfs:label "negative regulation of endodermal cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of endodermal cell differentiation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:als") Annotation( "GO_REF:0000058") Annotation( "PMID:23154389") "Any process that activates or increases the frequency, rate or extent of endodermal cell differentiation.") -AnnotationAssertion( "als") -AnnotationAssertion( "2014-07-29T13:22:47Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of endoderm cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of endoderm cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of endodermal cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of endoderm cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of endodermal cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of endoderm cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of endodermal cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of endoderm cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of endodermal cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903226") -AnnotationAssertion(rdfs:label "positive regulation of endodermal cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (melanosome assembly) - -AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:TermGenie") Annotation( "GOC:bf") Annotation( "GO_REF:0000079") Annotation( "PMID:22511774") "The aggregation, arrangement and bonding together of a set of components to form a melanosome, a tissue-specific, membrane-bounded cytoplasmic organelle within which melanin pigments are synthesized and stored.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2014-07-31T10:41:38Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "melanosome formation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903232") -AnnotationAssertion(rdfs:label "melanosome assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (multi-ciliated epithelial cell differentiation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:sp") Annotation( "GO_REF:0000086") Annotation( "PMID:22231168") Annotation( "PMID:24934224") "The process in which a relatively unspecialized cell acquires the specialized features of a multi-ciliated epithelial cell.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2014-08-05T19:21:21Z") -AnnotationAssertion( "multiciliate cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903251") -AnnotationAssertion(rdfs:label "multi-ciliated epithelial cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of sodium ion export across plasma membrane) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "GO_REF:0000058") Annotation( "PMID:17095720") "Any process that modulates the frequency, rate or extent of sodium ion export across the plasma membrane.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2014-08-08T17:06:46Z") -AnnotationAssertion( "GO:1903273") -AnnotationAssertion( "regulation of sodium ion export from cell") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of sodium export") -AnnotationAssertion( "regulation of sodium ion export") -AnnotationAssertion( "GO:1903276") -AnnotationAssertion(rdfs:label "regulation of sodium ion export across plasma membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of sodium ion export across plasma membrane) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "GO_REF:0000058") Annotation( "PMID:17095720") "Any process that stops, prevents or reduces the frequency, rate or extent of sodium ion export across the plasma membrane.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2014-08-08T17:10:22Z") -AnnotationAssertion( "GO:1903274") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of sodium ion export from cell") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of sodium ion export from cell") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of sodium ion export from cell") -AnnotationAssertion( "negative regulation of sodium ion export from cell") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of sodium export") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of sodium ion export") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of sodium ion export from cell") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of sodium export") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of sodium ion export") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of sodium export") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of sodium ion export") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of sodium export") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of sodium ion export") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of sodium export") -AnnotationAssertion( "negative regulation of sodium ion export") -AnnotationAssertion( "GO:1903277") -AnnotationAssertion(rdfs:label "negative regulation of sodium ion export across plasma membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of sodium ion export across plasma membrane) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "GO_REF:0000058") Annotation( "PMID:17095720") "Any process that activates or increases the frequency, rate or extent of sodium ion export across the plasma membrane.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2014-08-08T17:10:30Z") -AnnotationAssertion( "GO:1903275") -AnnotationAssertion( "positive regulation of sodium ion export from cell") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of sodium ion export from cell") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of sodium ion export from cell") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of sodium ion export from cell") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of sodium export") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of sodium ion export") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of sodium ion export from cell") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of sodium export") -AnnotationAssertion( "positive regulation of sodium ion export") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of sodium export") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of sodium ion export") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of sodium export") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of sodium ion export") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of sodium export") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of sodium ion export") -AnnotationAssertion( "GO:1903278") -AnnotationAssertion(rdfs:label "positive regulation of sodium ion export across plasma membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (protein localization to Golgi membrane) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000087") Annotation( "PMID:11378902") "A process in which a protein is transported to, or maintained in, a location within a Golgi membrane.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2014-08-12T14:22:31Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "protein localisation in Golgi membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "protein localisation to Golgi membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "protein localization in Golgi membrane") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903292") -AnnotationAssertion(rdfs:label "protein localization to Golgi membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of glutamate secretion, neurotransmission) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:16782817") "Any process that modulates the frequency, rate or extent of glutamate secretion, neurotransmission.") -AnnotationAssertion( "pad") -AnnotationAssertion( "2014-08-13T13:54:15Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903294") -AnnotationAssertion(rdfs:comment "An example of this is Rab3gap1 in mouse (Q80UJ7) in PMID:16782817 inferred from mutant phenotype") -AnnotationAssertion(rdfs:label "regulation of glutamate secretion, neurotransmission") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (negative regulation of glutamate secretion, neurotransmission) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:16782817") "Any process that stops, prevents or reduces the frequency, rate or extent of glutamate secretion, neurotransmission.") -AnnotationAssertion( "pad") -AnnotationAssertion( "2014-08-13T13:54:23Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of glutamate secretion, neurotransmission") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of glutamate secretion, neurotransmission") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of glutamate secretion, neurotransmission") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of glutamate secretion, neurotransmission") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903295") -AnnotationAssertion(rdfs:comment "An example of this is Rab3gap1 in mouse (Q80UJ7) in PMID:16782817 inferred from mutant phenotype") -AnnotationAssertion(rdfs:label "negative regulation of glutamate secretion, neurotransmission") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of glutamate secretion, neurotransmission) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:16782817") "Any process that activates or increases the frequency, rate or extent of glutamate secretion, where glutamate acts as a neurotransmitter.") -AnnotationAssertion( "pad") -AnnotationAssertion( "2014-08-13T13:54:31Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of glutamate secretion, neurotransmission") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of glutamate secretion, neurotransmission") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of glutamate secretion, neurotransmission") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of glutamate secretion, neurotransmission") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903296") -AnnotationAssertion(rdfs:comment "An example of this is Rab3gap1 in mouse (Q80UJ7) in PMID:16782817 inferred from mutant phenotype") -AnnotationAssertion(rdfs:label "positive regulation of glutamate secretion, neurotransmission") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (regulation of regulated secretory pathway) - -AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:TermGenie") Annotation( "GOC:pad") Annotation( "GO_REF:0000058") Annotation( "PMID:12526776") "Any process that modulates the frequency, rate or extent of regulated secretory pathway.") -AnnotationAssertion( "pad") -AnnotationAssertion( "2014-08-18T10:04:53Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903305") -AnnotationAssertion(rdfs:comment "An example of this is protein domain-specific expression of Synaptotagmin 1 in rat (P21707) in PMID:12526776 inferred from mutant phenotype.") -AnnotationAssertion(rdfs:label "regulation of regulated secretory pathway") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of regulated secretory pathway) - -AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:TermGenie") Annotation( "GOC:pad") Annotation( "GO_REF:0000058") Annotation( "PMID:12526776") "Any process that stops, prevents or reduces the frequency, rate or extent of regulated secretory pathway.") -AnnotationAssertion( "pad") -AnnotationAssertion( "2014-08-18T10:05:02Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of regulated secretory pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of regulated secretory pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of regulated secretory pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of regulated secretory pathway") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903306") -AnnotationAssertion(rdfs:comment "An example of this is protein domain-specific expression of Synaptotagmin 1 in rat (P21707) in PMID:12526776 inferred from mutant phenotype.") -AnnotationAssertion(rdfs:label "negative regulation of regulated secretory pathway") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of regulated secretory pathway) - -AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:TermGenie") Annotation( "GOC:pad") Annotation( "GO_REF:0000058") Annotation( "PMID:12526776") "Any process that activates or increases the frequency, rate or extent of regulated secretory pathway.") -AnnotationAssertion( "pad") -AnnotationAssertion( "2014-08-18T10:05:10Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of regulated secretory pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of regulated secretory pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of regulated secretory pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of regulated secretory pathway") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903307") -AnnotationAssertion(rdfs:comment "An example of this is protein domain-specific expression of Synaptotagmin 1 in rat (P21707) in PMID:12526776 inferred from mutant phenotype.") -AnnotationAssertion(rdfs:label "positive regulation of regulated secretory pathway") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of protein maturation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:vw") Annotation( "GO_REF:0000058") "Any process that modulates the frequency, rate or extent of protein maturation.") -AnnotationAssertion( "vw") -AnnotationAssertion( "2014-08-18T12:59:07Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903317") -AnnotationAssertion(rdfs:label "regulation of protein maturation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (negative regulation of protein maturation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:vw") Annotation( "GO_REF:0000058") "Any process that stops, prevents or reduces the frequency, rate or extent of protein maturation.") -AnnotationAssertion( "vw") -AnnotationAssertion( "2014-08-18T12:59:15Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of protein maturation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of protein maturation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of protein maturation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of protein maturation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903318") -AnnotationAssertion(rdfs:label "negative regulation of protein maturation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of protein maturation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:vw") Annotation( "GO_REF:0000058") "Any process that activates or increases the frequency, rate or extent of protein maturation.") -AnnotationAssertion( "vw") -AnnotationAssertion( "2014-08-18T12:59:23Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of protein maturation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of protein maturation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of protein maturation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of protein maturation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903319") -AnnotationAssertion(rdfs:label "positive regulation of protein maturation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (regulation of vacuolar transport) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:vw") Annotation( "GO_REF:0000058") "Any process that modulates the frequency, rate or extent of vacuolar transport.") -AnnotationAssertion( "vw") -AnnotationAssertion( "2014-08-18T13:16:04Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903335") -AnnotationAssertion(rdfs:label "regulation of vacuolar transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of vacuolar transport) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:vw") Annotation( "GO_REF:0000058") "Any process that stops, prevents or reduces the frequency, rate or extent of vacuolar transport.") -AnnotationAssertion( "vw") -AnnotationAssertion( "2014-08-18T13:16:11Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of vacuolar transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of vacuolar transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of vacuolar transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of vacuolar transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903336") -AnnotationAssertion(rdfs:label "negative regulation of vacuolar transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of vacuolar transport) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:vw") Annotation( "GO_REF:0000058") "Any process that activates or increases the frequency, rate or extent of vacuolar transport.") -AnnotationAssertion( "vw") -AnnotationAssertion( "2014-08-18T13:16:19Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of vacuolar transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of vacuolar transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of vacuolar transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of vacuolar transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903337") -AnnotationAssertion(rdfs:label "positive regulation of vacuolar transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of bicellular tight junction assembly) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:jz") Annotation( "GO_REF:0000058") Annotation( "PMID:25050009") "Any process that stops, prevents or reduces the frequency, rate or extent of tight junction assembly.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2014-08-19T11:02:14Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of tight junction assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of tight junction formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of tight junction assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of tight junction formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of tight junction assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of tight junction formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of tight junction formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of tight junction assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of tight junction formation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903347") -AnnotationAssertion(rdfs:label "negative regulation of bicellular tight junction assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of bicellular tight junction assembly) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:jz") Annotation( "GO_REF:0000058") Annotation( "PMID:25050009") "Any process that activates or increases the frequency, rate or extent of tight junction assembly.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2014-08-19T11:05:06Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of tight junction formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of tight junction assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of tight junction formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of tight junction assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of tight junction formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of tight junction assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of tight junction formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of tight junction assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of tight junction formation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903348") -AnnotationAssertion(rdfs:label "positive regulation of bicellular tight junction assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (response to dopamine) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mr") Annotation( "GO_REF:0000071") Annotation( "PMID:11118945") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dopamine stimulus.") -AnnotationAssertion( "mr") -AnnotationAssertion( "2014-08-19T19:33:26Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903350") -AnnotationAssertion(rdfs:label "response to dopamine") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cellular response to dopamine) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mr") Annotation( "GO_REF:0000071") Annotation( "PMID:11118945") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dopamine stimulus.") -AnnotationAssertion( "mr") -AnnotationAssertion( "2014-08-19T19:33:35Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903351") -AnnotationAssertion(rdfs:label "cellular response to dopamine") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of nucleus organization) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:16943282") "Any process that modulates the frequency, rate or extent of nucleus organization.") -AnnotationAssertion( "hjd") -AnnotationAssertion( "2014-08-20T19:36:16Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of nuclear organisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of nuclear organization") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of nuclear morphology") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of nuclear organization and biogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of nucleus organization and biogenesis") -AnnotationAssertion( "GO:1903353") -AnnotationAssertion(rdfs:label "regulation of nucleus organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of Golgi organization) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:als") Annotation( "GO_REF:0000058") Annotation( "PMID:17562788") "Any process that modulates the frequency, rate or extent of Golgi organization.") -AnnotationAssertion( "als") -AnnotationAssertion( "2014-08-21T10:22:22Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of Golgi organisation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of Golgi organization and biogenesis") -AnnotationAssertion( "GO:1903358") -AnnotationAssertion(rdfs:label "regulation of Golgi organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (facioacoustic ganglion development) - -AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:TermGenie") Annotation( "GOC:bf") Annotation( "GOC:mat") Annotation( "GO_REF:0000094") Annotation( "PMID:18356247") "The process whose specific outcome is the progression of an acoustico-facial VII-VIII ganglion complex over time, from its formation to the mature structure.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2014-08-26T12:40:36Z") -AnnotationAssertion(Annotation( "UBERON:0012175") "acoustico-facial VII-VIII ganglion complex development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "acousticofacial ganglion development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "facio-acoustic VII-VIII ganglion complex development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "facio-acoustic ganglion complex VII-VIII development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "facio-acoustic ganglion development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903375") -AnnotationAssertion(rdfs:label "facioacoustic ganglion development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of mitotic chromosome condensation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:9490640") "Any process that modulates the frequency, rate or extent of mitotic chromosome condensation.") -AnnotationAssertion( "al") -AnnotationAssertion( "2014-08-26T13:57:13Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903379") -AnnotationAssertion(rdfs:label "regulation of mitotic chromosome condensation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of mitotic chromosome condensation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:9490640") "Any process that activates or increases the frequency, rate or extent of mitotic chromosome condensation.") -AnnotationAssertion( "al") -AnnotationAssertion( "2014-08-26T13:57:29Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of mitotic chromosome condensation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of mitotic chromosome condensation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of mitotic chromosome condensation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of mitotic chromosome condensation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903380") -AnnotationAssertion(rdfs:label "positive regulation of mitotic chromosome condensation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (response to bile acid) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "GO_REF:0000071") Annotation( "PMID:21757002") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bile acid stimulus.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2014-09-03T12:45:43Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903412") -AnnotationAssertion(rdfs:label "response to bile acid") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cellular response to bile acid) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "GO_REF:0000071") Annotation( "PMID:21757002") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bile acid stimulus.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2014-09-03T12:45:51Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903413") -AnnotationAssertion(rdfs:label "cellular response to bile acid") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of cell maturation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:17459944") "Any process that modulates the frequency, rate or extent of cell maturation.") -AnnotationAssertion( "jl") -AnnotationAssertion( "2014-09-15T13:31:23Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of functional differentiation") -AnnotationAssertion( "GO:1903429") -AnnotationAssertion(rdfs:label "regulation of cell maturation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (negative regulation of cell maturation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:17459944") "Any process that stops, prevents or reduces the frequency, rate or extent of cell maturation.") -AnnotationAssertion( "jl") -AnnotationAssertion( "2014-09-15T13:31:32Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of cell maturation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of cell maturation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of cell maturation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of cell maturation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of functional differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of functional differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of functional differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of functional differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of functional differentiation") -AnnotationAssertion( "GO:1903430") -AnnotationAssertion(rdfs:label "negative regulation of cell maturation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of cell maturation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:17459944") "Any process that activates or increases the frequency, rate or extent of cell maturation.") -AnnotationAssertion( "jl") -AnnotationAssertion( "2014-09-15T13:31:41Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of cell maturation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of cell maturation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of cell maturation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of cell maturation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of functional differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of functional differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of functional differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of functional differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of functional differentiation") -AnnotationAssertion( "GO:1903431") -AnnotationAssertion(rdfs:label "positive regulation of cell maturation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (calcitonin family receptor complex) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:bhm") Annotation( "GO_REF:0000088") Annotation( "PMID:10871296") Annotation( "PMID:12037140") Annotation( "PMID:18687416") "A protein complex which is capable of calcitonin family receptor activity. Calcitonin family receptors may form dimers, trimers or tetramers; adrenomedullin and amylin receptors have only been observed as dimers so far.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2014-09-16T13:25:11Z") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:1903439") -AnnotationAssertion(rdfs:label "calcitonin family receptor complex") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (protein localization to ciliary membrane) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:cilia") Annotation( "GOC:krc") Annotation( "GO_REF:0000087") Annotation( "PMID:22139371") "A process in which a protein is transported to, or maintained in, a location within a ciliary membrane.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2014-09-16T15:15:39Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "protein localisation in ciliary membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "protein localisation to ciliary membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "protein localization in ciliary membrane") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903441") -AnnotationAssertion(rdfs:label "protein localization to ciliary membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of brown fat cell differentiation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:23977283") "Any process that stops, prevents or reduces the frequency, rate or extent of brown fat cell differentiation.") -AnnotationAssertion( "hjd") -AnnotationAssertion( "2014-09-17T19:15:00Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of brown adipocyte cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of brown adipocyte differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of brown fat cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of brown adipocyte cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of brown adipocyte differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of brown fat cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of brown adipocyte cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of brown adipocyte differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of brown fat cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of brown adipocyte cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of brown adipocyte differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of brown adipocyte cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of brown adipocyte differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of brown fat cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903444") -AnnotationAssertion(rdfs:label "negative regulation of brown fat cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of lactation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mr") Annotation( "GO_REF:0000058") Annotation( "PMID:19563620") "Any process that modulates the frequency, rate or extent of lactation.") -AnnotationAssertion( "mr") -AnnotationAssertion( "2014-09-24T14:44:13Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903487") -AnnotationAssertion(rdfs:label "regulation of lactation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of lactation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mr") Annotation( "GO_REF:0000058") Annotation( "PMID:19563620") "Any process that stops, prevents or reduces the frequency, rate or extent of lactation.") -AnnotationAssertion( "mr") -AnnotationAssertion( "2014-09-24T14:44:22Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of lactation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of lactation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of lactation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of lactation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903488") -AnnotationAssertion(rdfs:label "negative regulation of lactation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of lactation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mr") Annotation( "GO_REF:0000058") Annotation( "PMID:19563620") "Any process that activates or increases the frequency, rate or extent of lactation.") -AnnotationAssertion( "mr") -AnnotationAssertion( "2014-09-24T14:44:30Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of lactation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of lactation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of lactation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of lactation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903489") -AnnotationAssertion(rdfs:label "positive regulation of lactation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (liposaccharide metabolic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:dph") Annotation( "GO_REF:0000068") Annotation( "PMID:9452964") "The chemical reactions and pathways involving liposaccharide.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2014-10-01T21:52:52Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "liposaccharide metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903509") -AnnotationAssertion(rdfs:label "liposaccharide metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (mucopolysaccharide metabolic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:dph") Annotation( "GO_REF:0000068") Annotation( "PMID:4236091") "The chemical reactions and pathways involving mucopolysaccharide.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2014-10-01T21:55:47Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "mucopolysaccharide metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903510") -AnnotationAssertion(rdfs:label "mucopolysaccharide metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (regulation of blood circulation) AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mr") Annotation( "GO_REF:0000058") Annotation( "PMID:10659969") "Any process that modulates the frequency, rate or extent of blood circulation.") @@ -124584,51 +28102,8 @@ AnnotationAssertion( "GOC:TermGenie") "regulation of hemolymph circulation") AnnotationAssertion( "GO:1903522") AnnotationAssertion(rdfs:label "regulation of blood circulation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (negative regulation of blood circulation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mr") Annotation( "GO_REF:0000058") Annotation( "PMID:10659969") "Any process that stops, prevents or reduces the frequency, rate or extent of blood circulation.") -AnnotationAssertion( "mr") -AnnotationAssertion( "2014-10-06T18:39:05Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of blood circulation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of blood circulation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of blood circulation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of blood circulation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of hemolymph circulation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of hemolymph circulation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of hemolymph circulation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of hemolymph circulation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of hemolymph circulation") -AnnotationAssertion( "GO:1903523") -AnnotationAssertion(rdfs:label "negative regulation of blood circulation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of blood circulation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mr") Annotation( "GO_REF:0000058") Annotation( "PMID:10659969") "Any process that activates or increases the frequency, rate or extent of blood circulation.") -AnnotationAssertion( "mr") -AnnotationAssertion( "2014-10-06T18:39:13Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of blood circulation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of blood circulation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of blood circulation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of blood circulation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of hemolymph circulation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of hemolymph circulation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of hemolymph circulation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of hemolymph circulation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of hemolymph circulation") -AnnotationAssertion( "GO:1903524") -AnnotationAssertion(rdfs:label "positive regulation of blood circulation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - # Class: (regulation of secretion by cell) AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:pm") Annotation( "GO_REF:0000058") Annotation( "PMID:12130530") "Any process that modulates the frequency, rate or extent of secretion by cell.") @@ -124638,9354 +28113,9 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:1903530") AnnotationAssertion(rdfs:label "regulation of secretion by cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) -# Class: (negative regulation of secretion by cell) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:pm") Annotation( "GO_REF:0000058") Annotation( "PMID:12130530") "Any process that stops, prevents or reduces the frequency, rate or extent of secretion by cell.") -AnnotationAssertion( "pm") -AnnotationAssertion( "2014-10-08T13:25:08Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of cellular secretion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of secretion by cell") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of cellular secretion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of secretion by cell") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of cellular secretion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of secretion by cell") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of cellular secretion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of cellular secretion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of secretion by cell") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903531") -AnnotationAssertion(rdfs:label "negative regulation of secretion by cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of secretion by cell) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:pm") Annotation( "GO_REF:0000058") Annotation( "PMID:12130530") "Any process that activates or increases the frequency, rate or extent of secretion by cell.") -AnnotationAssertion( "pm") -AnnotationAssertion( "2014-10-08T13:25:17Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of cellular secretion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of cellular secretion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of secretion by cell") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of cellular secretion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of secretion by cell") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of cellular secretion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of secretion by cell") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of cellular secretion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of secretion by cell") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903532") -AnnotationAssertion(rdfs:label "positive regulation of secretion by cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (meiotic cell cycle process involved in oocyte maturation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:jz") Annotation( "GO_REF:0000060") Annotation( "PMID:25212395") "Any meiotic cell cycle process that is involved in oocyte maturation.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2014-10-09T10:46:14Z") -AnnotationAssertion( "meiosis involved in oocyte maturation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903537") -AnnotationAssertion(rdfs:label "meiotic cell cycle process involved in oocyte maturation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of meiotic cell cycle process involved in oocyte maturation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:jz") Annotation( "GO_REF:0000058") Annotation( "PMID:25212395") "Any process that modulates the frequency, rate or extent of meiotic cell cycle process involved in oocyte maturation.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2014-10-09T10:52:38Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of meiosis involved in oocyte maturation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903538") -AnnotationAssertion(rdfs:label "regulation of meiotic cell cycle process involved in oocyte maturation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (protein localization to postsynaptic membrane) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:kmv") Annotation( "GO_REF:0000087") Annotation( "PMID:9753322") "A process in which a protein is transported to, or maintained in, a location within a postsynaptic membrane.") -AnnotationAssertion( "kmv") -AnnotationAssertion( "2014-10-10T11:23:53Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "protein localisation in postsynaptic membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "protein localisation to postsynaptic membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "protein localization in postsynaptic membrane") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903539") -AnnotationAssertion(rdfs:label "protein localization to postsynaptic membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (establishment of protein localization to postsynaptic membrane) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:kmv") Annotation( "GO_REF:0000087") Annotation( "PMID:9753322") "The directed movement of a protein to a specific location in a postsynaptic membrane.") -AnnotationAssertion( "kmv") -AnnotationAssertion( "2014-10-10T11:24:03Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "establishment of protein localisation in postsynaptic membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "establishment of protein localisation to postsynaptic membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "establishment of protein localization in postsynaptic membrane") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903540") -AnnotationAssertion(rdfs:label "establishment of protein localization to postsynaptic membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of exosomal secretion) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:24105262") "Any process that modulates the frequency, rate or extent of exosomal secretion.") -AnnotationAssertion( "pga") -AnnotationAssertion( "2014-10-14T11:38:52Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of exosomal secretory pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of extracellular vesicular exosome secretion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of secretion of exosome") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of exosomal protein secretion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903541") -AnnotationAssertion(rdfs:label "regulation of exosomal secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of exosomal secretion) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:24105262") "Any process that stops, prevents or reduces the frequency, rate or extent of exosomal secretion.") -AnnotationAssertion( "pga") -AnnotationAssertion( "2014-10-14T11:39:02Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of exosomal secretion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of exosomal secretory pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of extracellular vesicular exosome secretion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of secretion of exosome") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of exosomal secretion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of exosomal secretory pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of extracellular vesicular exosome secretion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of secretion of exosome") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of exosomal secretion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of exosomal secretory pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of extracellular vesicular exosome secretion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of secretion of exosome") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of exosomal secretory pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of extracellular vesicular exosome secretion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of secretion of exosome") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of exosomal protein secretion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of exosomal protein secretion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of exosomal protein secretion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of exosomal protein secretion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of exosomal secretion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of exosomal secretory pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of extracellular vesicular exosome secretion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of secretion of exosome") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of exosomal protein secretion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903542") -AnnotationAssertion(rdfs:label "negative regulation of exosomal secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of exosomal secretion) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:24105262") "Any process that activates or increases the frequency, rate or extent of exosomal secretion.") -AnnotationAssertion( "pga") -AnnotationAssertion( "2014-10-14T11:39:10Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of exosomal secretory pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of extracellular vesicular exosome secretion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of secretion of exosome") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of exosomal secretion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of exosomal secretory pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of extracellular vesicular exosome secretion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of secretion of exosome") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of exosomal secretion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of exosomal secretory pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of extracellular vesicular exosome secretion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of secretion of exosome") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of exosomal secretion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of exosomal secretory pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of extracellular vesicular exosome secretion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of secretion of exosome") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of exosomal protein secretion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of exosomal secretion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of exosomal secretory pathway") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of extracellular vesicular exosome secretion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of secretion of exosome") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of exosomal protein secretion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of exosomal protein secretion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of exosomal protein secretion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of exosomal protein secretion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903543") -AnnotationAssertion(rdfs:label "positive regulation of exosomal secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (response to butyrate) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mr") Annotation( "GO_REF:0000071") Annotation( "PMID:9734870") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a butyrate stimulus.") -AnnotationAssertion( "mr") -AnnotationAssertion( "2014-10-17T13:57:25Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903544") -AnnotationAssertion(rdfs:label "response to butyrate") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cellular response to butyrate) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mr") Annotation( "GO_REF:0000071") Annotation( "PMID:9734870") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a butyrate stimulus.") -AnnotationAssertion( "mr") -AnnotationAssertion( "2014-10-17T13:57:35Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903545") -AnnotationAssertion(rdfs:label "cellular response to butyrate") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (protein localization to photoreceptor outer segment) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000087") Annotation( "PMID:11481257") Annotation( "PMID:21867699") "A process in which a protein is transported to, or maintained in, a location within a photoreceptor outer segment.") -AnnotationAssertion( "krc") -AnnotationAssertion( "2014-10-17T21:14:11Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "protein localisation in photoreceptor outer segment") -AnnotationAssertion(Annotation( "GOC:TermGenie") "protein localisation to photoreceptor outer segment") -AnnotationAssertion(Annotation( "GOC:TermGenie") "protein localization in photoreceptor outer segment") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903546") -AnnotationAssertion(rdfs:label "protein localization to photoreceptor outer segment") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of extracellular exosome assembly) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:24105262") "Any process that modulates the frequency, rate or extent of extracellular vesicular exosome assembly.") -AnnotationAssertion( "pga") -AnnotationAssertion( "2014-10-20T15:37:25Z") -AnnotationAssertion(Annotation( "GOC:vesicles") "regulation of extracellular vesicular exosome assembly") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903551") -AnnotationAssertion(rdfs:label "regulation of extracellular exosome assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of extracellular exosome assembly) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:24105262") "Any process that stops, prevents or reduces the frequency, rate or extent of extracellular vesicular exosome assembly.") -AnnotationAssertion( "pga") -AnnotationAssertion( "2014-10-20T15:37:33Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of extracellular vesicular exosome assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of extracellular vesicular exosome assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of extracellular vesicular exosome assembly") -AnnotationAssertion(Annotation( "GOC:vesicles") "negative regulation of extracellular vesicular exosome assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of extracellular vesicular exosome assembly") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903552") -AnnotationAssertion(rdfs:label "negative regulation of extracellular exosome assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of extracellular exosome assembly) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:24105262") "Any process that activates or increases the frequency, rate or extent of extracellular vesicular exosome assembly.") -AnnotationAssertion( "pga") -AnnotationAssertion( "2014-10-20T15:37:42Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of extracellular vesicular exosome assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of extracellular vesicular exosome assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of extracellular vesicular exosome assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of extracellular vesicular exosome assembly") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:vesicles") "positive regulation of extracellular vesicular exosome assembly") -AnnotationAssertion( "GO:1903553") -AnnotationAssertion(rdfs:label "positive regulation of extracellular exosome assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (extracellular vesicle) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:pm") Annotation( "GO_REF:0000064") Annotation( "PMID:24769233") "Any vesicle that is part of the extracellular region.") -AnnotationAssertion( "jl") -AnnotationAssertion( "2014-10-22T14:26:11Z") -AnnotationAssertion( "cellular_component") -AnnotationAssertion(Annotation( "GOC:vesicles") "microparticle") -AnnotationAssertion( "GO:1903561") -AnnotationAssertion(rdfs:label "extracellular vesicle") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of protein localization to cilium) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:cilia") Annotation( "GOC:krc") Annotation( "GO_REF:0000058") Annotation( "PMID:22072986") "Any process that modulates the frequency, rate or extent of protein localization to cilium.") -AnnotationAssertion( "krc") -AnnotationAssertion( "2014-10-24T20:58:11Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903564") -AnnotationAssertion(rdfs:label "regulation of protein localization to cilium") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of protein localization to cilium) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:cilia") Annotation( "GOC:krc") Annotation( "GO_REF:0000058") Annotation( "PMID:22072986") "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cilium.") -AnnotationAssertion( "krc") -AnnotationAssertion( "2014-10-24T20:58:20Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of protein localization to cilium") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of protein localization to cilium") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of protein localization to cilium") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of protein localization to cilium") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903565") -AnnotationAssertion(rdfs:label "negative regulation of protein localization to cilium") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of protein localization to cilium) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:cilia") Annotation( "GOC:krc") Annotation( "GO_REF:0000058") Annotation( "PMID:22072986") "Any process that activates or increases the frequency, rate or extent of protein localization to cilium.") -AnnotationAssertion( "krc") -AnnotationAssertion( "2014-10-24T20:58:28Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of protein localization to cilium") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of protein localization to cilium") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of protein localization to cilium") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of protein localization to cilium") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903566") -AnnotationAssertion(rdfs:label "positive regulation of protein localization to cilium") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of protein localization to ciliary membrane) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:cilia") Annotation( "GOC:krc") Annotation( "GO_REF:0000058") Annotation( "PMID:22072986") "Any process that modulates the frequency, rate or extent of protein localization to ciliary membrane.") -AnnotationAssertion( "krc") -AnnotationAssertion( "2014-10-24T21:32:51Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of protein localisation in ciliary membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of protein localisation to ciliary membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of protein localization in ciliary membrane") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903567") -AnnotationAssertion(rdfs:label "regulation of protein localization to ciliary membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of protein localization to ciliary membrane) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:cilia") Annotation( "GOC:krc") Annotation( "GO_REF:0000058") Annotation( "PMID:22072986") "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to ciliary membrane.") -AnnotationAssertion( "krc") -AnnotationAssertion( "2014-10-24T21:32:59Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of protein localisation in ciliary membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of protein localisation to ciliary membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of protein localization in ciliary membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of protein localization to ciliary membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of protein localisation in ciliary membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of protein localisation to ciliary membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of protein localization in ciliary membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of protein localization to ciliary membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of protein localisation in ciliary membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of protein localisation to ciliary membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of protein localization in ciliary membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of protein localization to ciliary membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of protein localisation in ciliary membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of protein localisation to ciliary membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of protein localization in ciliary membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of protein localisation in ciliary membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of protein localisation to ciliary membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of protein localization in ciliary membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of protein localization to ciliary membrane") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903568") -AnnotationAssertion(rdfs:label "negative regulation of protein localization to ciliary membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of protein localization to ciliary membrane) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:cilia") Annotation( "GOC:krc") Annotation( "GO_REF:0000058") Annotation( "PMID:22072986") "Any process that activates or increases the frequency, rate or extent of protein localization to ciliary membrane.") -AnnotationAssertion( "krc") -AnnotationAssertion( "2014-10-24T21:33:08Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of protein localisation in ciliary membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of protein localisation to ciliary membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of protein localization in ciliary membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of protein localisation in ciliary membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of protein localisation to ciliary membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of protein localization in ciliary membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of protein localization to ciliary membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of protein localisation in ciliary membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of protein localisation to ciliary membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of protein localization in ciliary membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of protein localization to ciliary membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of protein localisation in ciliary membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of protein localisation to ciliary membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of protein localization in ciliary membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of protein localization to ciliary membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of protein localisation in ciliary membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of protein localisation to ciliary membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of protein localization in ciliary membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of protein localization to ciliary membrane") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903569") -AnnotationAssertion(rdfs:label "positive regulation of protein localization to ciliary membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of ATP metabolic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:20695849") "Any process that modulates the frequency, rate or extent of ATP metabolic process.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2014-10-30T19:04:24Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of ATP metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903578") -AnnotationAssertion(rdfs:label "regulation of ATP metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of ATP metabolic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:20695849") "Any process that stops, prevents or reduces the frequency, rate or extent of ATP metabolic process.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2014-10-30T19:04:33Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of ATP metabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of ATP metabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of ATP metabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of ATP metabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of ATP metabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of ATP metabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of ATP metabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of ATP metabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of ATP metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903579") -AnnotationAssertion(rdfs:label "negative regulation of ATP metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of ATP metabolic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:20695849") "Any process that activates or increases the frequency, rate or extent of ATP metabolic process.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2014-10-30T19:04:42Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of ATP metabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of ATP metabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of ATP metabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of ATP metabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of ATP metabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of ATP metabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of ATP metabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of ATP metabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of ATP metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903580") -AnnotationAssertion(rdfs:label "positive regulation of ATP metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of DNA catabolic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:2001740") "Any process that modulates the frequency, rate or extent of DNA catabolic process.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2014-11-19T22:36:35Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of DNA breakdown") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of DNA catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of DNA degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903624") -AnnotationAssertion(rdfs:label "regulation of DNA catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of DNA catabolic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:2001740") "Any process that stops, prevents or reduces the frequency, rate or extent of DNA catabolic process.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2014-11-19T22:36:43Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of DNA breakdown") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of DNA catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of DNA catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of DNA degradation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of DNA breakdown") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of DNA catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of DNA catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of DNA degradation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of DNA breakdown") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of DNA catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of DNA catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of DNA degradation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of DNA breakdown") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of DNA catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of DNA degradation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of DNA breakdown") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of DNA catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of DNA catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of DNA degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903625") -AnnotationAssertion(rdfs:label "negative regulation of DNA catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of DNA catabolic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:2001740") "Any process that activates or increases the frequency, rate or extent of DNA catabolic process.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2014-11-19T22:36:51Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of DNA breakdown") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of DNA catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of DNA degradation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of DNA breakdown") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of DNA catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of DNA catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of DNA degradation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of DNA breakdown") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of DNA catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of DNA catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of DNA degradation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of DNA breakdown") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of DNA catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of DNA catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of DNA degradation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of DNA breakdown") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of DNA catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of DNA catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of DNA degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903626") -AnnotationAssertion(rdfs:label "positive regulation of DNA catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of cytoplasmic transport) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:25049409") "Any process that modulates the frequency, rate or extent of cytoplasmic transport.") -AnnotationAssertion( "jl") -AnnotationAssertion( "2014-11-24T13:38:17Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of cytoplasmic streaming") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903649") -AnnotationAssertion(rdfs:label "regulation of cytoplasmic transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of cytoplasmic transport) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:25049409") "Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic transport.") -AnnotationAssertion( "jl") -AnnotationAssertion( "2014-11-24T13:38:26Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of cytoplasmic transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of cytoplasmic transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of cytoplasmic transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of cytoplasmic streaming") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of cytoplasmic streaming") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of cytoplasmic streaming") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of cytoplasmic streaming") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of cytoplasmic transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of cytoplasmic streaming") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903650") -AnnotationAssertion(rdfs:label "negative regulation of cytoplasmic transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of cytoplasmic transport) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:25049409") "Any process that activates or increases the frequency, rate or extent of cytoplasmic transport.") -AnnotationAssertion( "jl") -AnnotationAssertion( "2014-11-24T13:38:34Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of cytoplasmic transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of cytoplasmic transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of cytoplasmic transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of cytoplasmic streaming") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of cytoplasmic transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of cytoplasmic streaming") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of cytoplasmic streaming") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of cytoplasmic streaming") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of cytoplasmic streaming") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903651") -AnnotationAssertion(rdfs:label "positive regulation of cytoplasmic transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (acinar cell of sebaceous gland differentiation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000086") Annotation( "PMID:17018284") Annotation( "PMID:18334552") Annotation( "PMID:19944183") "The process in which a relatively unspecialized cell acquires the specialized features of an acinar cell of sebaceous gland.") -AnnotationAssertion( "cls") -AnnotationAssertion( "2014-11-30T11:51:57Z") -AnnotationAssertion(Annotation( "CL:0002140") "sebocyte differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903680") -AnnotationAssertion(rdfs:label "acinar cell of sebaceous gland differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of microvillus assembly) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:als") Annotation( "GO_REF:0000058") Annotation( "PMID:22797597") "Any process that stops, prevents or reduces the frequency, rate or extent of microvillus assembly.") -AnnotationAssertion( "als") -AnnotationAssertion( "2014-12-03T11:45:08Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of microvillus assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of microvillus assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of microvillus assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of microvillus assembly") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of microvillus biogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of microvillus biogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of microvillus biogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of microvillus biogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of microvillus biogenesis") -AnnotationAssertion( "GO:1903697") -AnnotationAssertion(rdfs:label "negative regulation of microvillus assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of microvillus assembly) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:als") Annotation( "GO_REF:0000058") Annotation( "PMID:22797597") "Any process that activates or increases the frequency, rate or extent of microvillus assembly.") -AnnotationAssertion( "als") -AnnotationAssertion( "2014-12-03T11:45:17Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of microvillus assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of microvillus assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of microvillus assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of microvillus assembly") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of microvillus biogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of microvillus biogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of microvillus biogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of microvillus biogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of microvillus biogenesis") -AnnotationAssertion( "GO:1903698") -AnnotationAssertion(rdfs:label "positive regulation of microvillus assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (tarsal gland development) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000094") Annotation( "PMID:20664693") "The process whose specific outcome is the progression of a tarsal gland over time, from its formation to the mature structure.") -AnnotationAssertion( "cls") -AnnotationAssertion( "2014-12-03T11:47:07Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "Meibomian gland development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "gland of Meibom development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "glandula tarsales development") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "tarsoconjunctival gland development") -AnnotationAssertion( "GO:1903699") -AnnotationAssertion(rdfs:label "tarsal gland development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (caecum development) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000094") Annotation( "ISBN:0-683-40008-8") "The process whose specific outcome is the progression of a caecum over time, from its formation to the mature structure.") -AnnotationAssertion( "cls") -AnnotationAssertion( "2014-12-03T12:05:00Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "cecum development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "intestinum crassum caecum development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "caeca development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "ceca development") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "blind intestine development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "blindgut development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "intestinum caecum development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "intestinum crassum cecum development") -AnnotationAssertion( "GO:1903700") -AnnotationAssertion(rdfs:label "caecum development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (substantia propria of cornea development) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000094") Annotation( "PMID:12556382") "The process whose specific outcome is the progression of a substantia propria of cornea over time, from its formation to the mature structure.") -AnnotationAssertion( "cls") -AnnotationAssertion( "2014-12-03T13:12:09Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "corneal stroma development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "stroma of cornea development") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "substantia propria development") -AnnotationAssertion( "GO:1903701") -AnnotationAssertion(rdfs:label "substantia propria of cornea development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (esophagus development) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000094") Annotation( "ISBN:0-683-40008-8") "The process whose specific outcome is the progression of an esophagus over time, from its formation to the mature structure.") -AnnotationAssertion( "cls") -AnnotationAssertion( "2014-12-03T14:41:30Z") -AnnotationAssertion(Annotation( "MGI:csmith") "esophageal development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "gullet development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "oesophagus development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903702") -AnnotationAssertion(rdfs:label "esophagus development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of hemopoiesis) - -AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:TermGenie") Annotation( "GOC:pad") Annotation( "GO_REF:0000058") Annotation( "PMID:20080761") "Any process that modulates the frequency, rate or extent of hemopoiesis.") -AnnotationAssertion( "pad") -AnnotationAssertion( "2014-12-04T15:34:13Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of blood cell biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of blood cell formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of haemopoiesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of hematopoiesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903706") -AnnotationAssertion(rdfs:comment "An example of this is Atg7 in mouse (UniProt symbol, Q9D906) in PMID:20080761, inferred from mutant phenotype.") -AnnotationAssertion(rdfs:label "regulation of hemopoiesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of hemopoiesis) - -AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:TermGenie") Annotation( "GOC:pad") Annotation( "GO_REF:0000058") Annotation( "PMID:20080761") "Any process that stops, prevents or reduces the frequency, rate or extent of hemopoiesis.") -AnnotationAssertion( "pad") -AnnotationAssertion( "2014-12-04T15:34:21Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of blood cell biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of blood cell formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of haemopoiesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of hematopoiesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of hemopoiesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of blood cell biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of blood cell formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of haemopoiesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of hematopoiesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of hemopoiesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of blood cell biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of blood cell formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of haemopoiesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of hematopoiesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of hemopoiesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of blood cell biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of blood cell formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of haemopoiesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of hematopoiesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of blood cell biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of blood cell formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of haemopoiesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of hematopoiesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of hemopoiesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903707") -AnnotationAssertion(rdfs:comment "An example of this is Atg7 in mouse (UniProt symbol, Q9D906) in PMID:20080761, inferred from mutant phenotype.") -AnnotationAssertion(rdfs:label "negative regulation of hemopoiesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of hemopoiesis) - -AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:TermGenie") Annotation( "GOC:pad") Annotation( "GO_REF:0000058") Annotation( "PMID:20080761") "Any process that activates or increases the frequency, rate or extent of hemopoiesis.") -AnnotationAssertion( "pad") -AnnotationAssertion( "2014-12-04T15:34:30Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of blood cell biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of blood cell formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of haemopoiesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of hematopoiesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of blood cell biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of blood cell formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of haemopoiesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of hematopoiesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of hemopoiesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of blood cell biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of blood cell formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of haemopoiesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of hematopoiesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of hemopoiesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of blood cell biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of blood cell formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of haemopoiesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of hematopoiesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of hemopoiesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of blood cell biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of blood cell formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of haemopoiesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of hematopoiesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of hemopoiesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903708") -AnnotationAssertion(rdfs:comment "An example of this is Atg7 in mouse (UniProt symbol, Q9D906) in PMID:20080761, inferred from mutant phenotype.") -AnnotationAssertion(rdfs:label "positive regulation of hemopoiesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (uterine gland development) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000094") Annotation( "PMID:23619340") "The process whose specific outcome is the progression of an uterine gland over time, from its formation to the mature structure.") -AnnotationAssertion( "cls") -AnnotationAssertion( "2014-12-04T18:57:21Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "endometrial gland development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "endometrium gland development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "uterine glands development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "uterine glands set development") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "glandulae uterinae development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "glandular part of endometrium development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "set of uterine glands development") -AnnotationAssertion( "GO:1903709") -AnnotationAssertion(rdfs:label "uterine gland development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of phospholipid metabolic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:10657240") "Any process that modulates the frequency, rate or extent of phospholipid metabolic process.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2014-12-09T20:49:27Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of phospholipid metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903725") -AnnotationAssertion(rdfs:label "regulation of phospholipid metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of phospholipid metabolic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:10657240") "Any process that stops, prevents or reduces the frequency, rate or extent of phospholipid metabolic process.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2014-12-09T20:49:35Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of phospholipid metabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of phospholipid metabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of phospholipid metabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of phospholipid metabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of phospholipid metabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of phospholipid metabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of phospholipid metabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of phospholipid metabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of phospholipid metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903726") -AnnotationAssertion(rdfs:label "negative regulation of phospholipid metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of phospholipid metabolic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:10657240") "Any process that activates or increases the frequency, rate or extent of phospholipid metabolic process.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2014-12-09T20:49:44Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of phospholipid metabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of phospholipid metabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of phospholipid metabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of phospholipid metabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of phospholipid metabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of phospholipid metabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of phospholipid metabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of phospholipid metabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of phospholipid metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903727") -AnnotationAssertion(rdfs:label "positive regulation of phospholipid metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (luteal cell differentiation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000086") Annotation( "MP:0001133") "The process in which a relatively unspecialized cell acquires the specialized features of a luteal cell. Large luteal cells develop from granulosa cells. Small luteal cells develop from theca cells.") -AnnotationAssertion( "cjm") -AnnotationAssertion( "2014-12-10T01:36:43Z") -AnnotationAssertion(Annotation( "CL:0000175") "lutein cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903728") -AnnotationAssertion(rdfs:label "luteal cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of plasma membrane organization) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:24514900") "Any process that modulates the frequency, rate or extent of plasma membrane organization.") -AnnotationAssertion( "al") -AnnotationAssertion( "2014-12-10T18:59:44Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of plasma membrane organisation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of plasma membrane organization and biogenesis") -AnnotationAssertion( "GO:1903729") -AnnotationAssertion(rdfs:label "regulation of plasma membrane organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (protein localization to vacuolar membrane) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000087") Annotation( "PMID:25378562") "A process in which a protein is transported to, or maintained in, a location within a vacuolar membrane.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2015-01-07T13:15:54Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "protein localisation in vacuolar membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "protein localisation to vacuolar membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "protein localization in vacuolar membrane") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903778") -AnnotationAssertion(rdfs:label "protein localization to vacuolar membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of cardiac conduction) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:mtg_cardiac_conduct_nov11") Annotation( "GOC:rph") Annotation( "GO_REF:0000058") Annotation( "PMID:12967627") "Any process that modulates the frequency, rate or extent of cardiac conduction.") -AnnotationAssertion( "rph") -AnnotationAssertion( "2015-01-07T13:20:11Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903779") -AnnotationAssertion(rdfs:label "regulation of cardiac conduction") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of cardiac conduction) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:mtg_cardiac_conduct_nov11") Annotation( "GOC:rph") Annotation( "GO_REF:0000058") Annotation( "PMID:12967627") "Any process that stops, prevents or reduces the frequency, rate or extent of cardiac conduction.") -AnnotationAssertion( "rph") -AnnotationAssertion( "2015-01-07T13:20:20Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of cardiac conduction") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of cardiac conduction") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of cardiac conduction") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of cardiac conduction") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903780") -AnnotationAssertion(rdfs:label "negative regulation of cardiac conduction") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of cardiac conduction) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:mtg_cardiac_conduct_nov11") Annotation( "GOC:rph") Annotation( "GO_REF:0000058") Annotation( "PMID:12967627") "Any process that activates or increases the frequency, rate or extent of cardiac conduction.") -AnnotationAssertion( "rph") -AnnotationAssertion( "2015-01-07T13:20:28Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of cardiac conduction") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of cardiac conduction") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of cardiac conduction") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of cardiac conduction") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903781") -AnnotationAssertion(rdfs:label "positive regulation of cardiac conduction") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of sodium ion import across plasma membrane) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:mtg_cardiac_conduct_nov11") Annotation( "GOC:nc") Annotation( "GO_REF:0000058") Annotation( "PMID:19376779") "Any process that modulates the frequency, rate or extent of sodium ion import across the plasma membrane.") -AnnotationAssertion( "nc") -AnnotationAssertion( "2015-01-07T16:48:43Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903782") -AnnotationAssertion(rdfs:label "regulation of sodium ion import across plasma membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of sodium ion import across plasma membrane) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:mtg_cardiac_conduct_nov11") Annotation( "GOC:nc") Annotation( "GO_REF:0000058") Annotation( "PMID:19376779") "Any process that stops, prevents or reduces the frequency, rate or extent of sodium ion import across the plasma membrane.") -AnnotationAssertion( "nc") -AnnotationAssertion( "2015-01-07T16:48:51Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of sodium ion import across plasma membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of sodium ion import across plasma membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of sodium ion import across plasma membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of sodium ion import across plasma membrane") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903783") -AnnotationAssertion(rdfs:label "negative regulation of sodium ion import across plasma membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of sodium ion import across plasma membrane) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:mtg_cardiac_conduct_nov11") Annotation( "GOC:nc") Annotation( "GO_REF:0000058") Annotation( "PMID:19376779") "Any process that activates or increases the frequency, rate or extent of sodium ion import across the plasma membrane.") -AnnotationAssertion( "nc") -AnnotationAssertion( "2015-01-07T16:49:00Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of sodium ion import across plasma membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of sodium ion import across plasma membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of sodium ion import across plasma membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of sodium ion import across plasma membrane") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903784") -AnnotationAssertion(rdfs:label "positive regulation of sodium ion import across plasma membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of amino acid transmembrane transport) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:16115814") "Any process that modulates the frequency, rate or extent of amino acid transmembrane transport.") -AnnotationAssertion( "al") -AnnotationAssertion( "2015-01-08T17:42:18Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of amino acid membrane transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903789") -AnnotationAssertion(rdfs:label "regulation of amino acid transmembrane transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of inorganic anion transmembrane transport) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:11336802") "Any process that modulates the frequency, rate or extent of inorganic anion transmembrane transport.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-01-14T21:44:49Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of inorganic anion membrane transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of transmembrane inorganic anion transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903795") -AnnotationAssertion(rdfs:label "regulation of inorganic anion transmembrane transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of inorganic anion transmembrane transport) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:11336802") "Any process that stops, prevents or reduces the frequency, rate or extent of inorganic anion transmembrane transport.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-01-14T21:44:59Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of inorganic anion membrane transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of inorganic anion transmembrane transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of transmembrane inorganic anion transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of inorganic anion membrane transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of inorganic anion transmembrane transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of transmembrane inorganic anion transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of inorganic anion membrane transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of inorganic anion transmembrane transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of transmembrane inorganic anion transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of inorganic anion membrane transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of transmembrane inorganic anion transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of inorganic anion membrane transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of inorganic anion transmembrane transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of transmembrane inorganic anion transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903796") -AnnotationAssertion(rdfs:label "negative regulation of inorganic anion transmembrane transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of inorganic anion transmembrane transport) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:11336802") "Any process that activates or increases the frequency, rate or extent of inorganic anion transmembrane transport.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-01-14T21:45:08Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of inorganic anion membrane transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of transmembrane inorganic anion transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of inorganic anion membrane transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of inorganic anion transmembrane transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of transmembrane inorganic anion transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of inorganic anion membrane transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of inorganic anion transmembrane transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of transmembrane inorganic anion transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of inorganic anion membrane transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of inorganic anion transmembrane transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of transmembrane inorganic anion transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of inorganic anion membrane transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of inorganic anion transmembrane transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of transmembrane inorganic anion transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903797") -AnnotationAssertion(rdfs:label "positive regulation of inorganic anion transmembrane transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (organic acid transmembrane transport) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000069") "The process in which an organic acid is transported across a membrane.") -AnnotationAssertion( "vw") -AnnotationAssertion( "2015-01-20T10:20:58Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903825") -AnnotationAssertion(rdfs:label "organic acid transmembrane transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of protein localization) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:vw") Annotation( "GO_REF:0000058") "Any process that stops, prevents or reduces the frequency, rate or extent of a protein localization.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/22021"^^xsd:anyURI) -AnnotationAssertion( "jl") -AnnotationAssertion( "2015-01-20T14:32:24Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of cellular protein localisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of cellular protein localization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of cellular protein localisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of cellular protein localization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of cellular protein localisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of cellular protein localization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of cellular protein localisation") -AnnotationAssertion( "negative regulation of cellular protein localization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of cellular protein localisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of cellular protein localization") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903828") -AnnotationAssertion(rdfs:label "negative regulation of protein localization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of protein localization) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:vw") Annotation( "GO_REF:0000058") "Any process that activates or increases the frequency, rate or extent of a protein localization.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/22021"^^xsd:anyURI) -AnnotationAssertion( "jl") -AnnotationAssertion( "2015-01-20T14:32:33Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of cellular protein localisation") -AnnotationAssertion( "positive regulation of cellular protein localization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of cellular protein localisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of cellular protein localization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of cellular protein localisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of cellular protein localization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of cellular protein localisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of cellular protein localization") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903829") -AnnotationAssertion(rdfs:label "positive regulation of protein localization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (signal transduction involved in cellular response to ammonium ion) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000060") Annotation( "PMID:16297994") "Any signal transduction that is involved in cellular response to ammonium ion.") -AnnotationAssertion( "al") -AnnotationAssertion( "2015-01-21T17:52:09Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "signaling cascade involved in cellular response to ammonium ion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "signalling cascade involved in cellular response to ammonium ion") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "signaling pathway involved in cellular response to ammonium ion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "signalling pathway involved in cellular response to ammonium ion") -AnnotationAssertion( "GO:1903831") -AnnotationAssertion(rdfs:label "signal transduction involved in cellular response to ammonium ion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of aorta morphogenesis) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_miRNA") Annotation( "GOC:TermGenie") Annotation( "GOC:rph") Annotation( "GO_REF:0000058") Annotation( "PMID:22269326") "Any process that modulates the frequency, rate or extent of aorta morphogenesis.") -AnnotationAssertion( "rph") -AnnotationAssertion( "2015-01-23T14:00:51Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903847") -AnnotationAssertion(rdfs:label "regulation of aorta morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of aorta morphogenesis) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_miRNA") Annotation( "GOC:TermGenie") Annotation( "GOC:rph") Annotation( "GO_REF:0000058") Annotation( "PMID:22269326") "Any process that stops, prevents or reduces the frequency, rate or extent of aorta morphogenesis.") -AnnotationAssertion( "rph") -AnnotationAssertion( "2015-01-23T14:01:01Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of aorta morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of aorta morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of aorta morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of aorta morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903848") -AnnotationAssertion(rdfs:label "negative regulation of aorta morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of aorta morphogenesis) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_miRNA") Annotation( "GOC:TermGenie") Annotation( "GOC:rph") Annotation( "GO_REF:0000058") Annotation( "PMID:22269326") "Any process that activates or increases the frequency, rate or extent of aorta morphogenesis.") -AnnotationAssertion( "rph") -AnnotationAssertion( "2015-01-23T14:01:09Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of aorta morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of aorta morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of aorta morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of aorta morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903849") -AnnotationAssertion(rdfs:label "positive regulation of aorta morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (extraembryonic membrane development) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000094") Annotation( "ISBN:0073040584") "The process whose specific outcome is the progression of an extraembryonic membrane over time, from its formation to the mature structure.") -AnnotationAssertion( "cjm") -AnnotationAssertion( "2015-02-05T00:42:16Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903867") -AnnotationAssertion(rdfs:label "extraembryonic membrane development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of establishment of T cell polarity) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:als") Annotation( "GO_REF:0000058") Annotation( "PMID:23575248") "Any process that modulates the frequency, rate or extent of establishment of T cell polarity.") -AnnotationAssertion( "als") -AnnotationAssertion( "2015-02-09T10:50:21Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of T cell polarization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of T lymphocyte polarization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of T-cell polarization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of establishment of T lymphocyte polarity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of establishment of T-cell polarity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of establishment of T-lymphocyte polarity") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903903") -AnnotationAssertion(rdfs:label "regulation of establishment of T cell polarity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of establishment of T cell polarity) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:als") Annotation( "GO_REF:0000058") Annotation( "PMID:23575248") "Any process that stops, prevents or reduces the frequency, rate or extent of establishment of T cell polarity.") -AnnotationAssertion( "als") -AnnotationAssertion( "2015-02-09T10:50:30Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of T cell polarization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of T lymphocyte polarization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of T-cell polarization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of establishment of T cell polarity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of establishment of T lymphocyte polarity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of establishment of T-cell polarity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of establishment of T-lymphocyte polarity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of T cell polarization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of T lymphocyte polarization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of T-cell polarization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of establishment of T cell polarity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of establishment of T lymphocyte polarity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of establishment of T-cell polarity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of establishment of T-lymphocyte polarity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of T cell polarization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of T lymphocyte polarization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of T-cell polarization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of establishment of T cell polarity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of establishment of T lymphocyte polarity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of establishment of T-cell polarity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of establishment of T-lymphocyte polarity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of T cell polarization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of T lymphocyte polarization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of T-cell polarization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of establishment of T lymphocyte polarity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of establishment of T-cell polarity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of establishment of T-lymphocyte polarity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of T cell polarization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of T lymphocyte polarization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of T-cell polarization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of establishment of T cell polarity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of establishment of T lymphocyte polarity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of establishment of T-cell polarity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of establishment of T-lymphocyte polarity") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903904") -AnnotationAssertion(rdfs:label "negative regulation of establishment of T cell polarity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of establishment of T cell polarity) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:als") Annotation( "GO_REF:0000058") Annotation( "PMID:23575248") "Any process that activates or increases the frequency, rate or extent of establishment of T cell polarity.") -AnnotationAssertion( "als") -AnnotationAssertion( "2015-02-09T10:50:40Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of T cell polarization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of T lymphocyte polarization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of T-cell polarization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of establishment of T lymphocyte polarity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of establishment of T-cell polarity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of establishment of T-lymphocyte polarity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of T cell polarization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of T lymphocyte polarization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of T-cell polarization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of establishment of T cell polarity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of establishment of T lymphocyte polarity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of establishment of T-cell polarity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of establishment of T-lymphocyte polarity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of T cell polarization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of T lymphocyte polarization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of T-cell polarization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of establishment of T cell polarity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of establishment of T lymphocyte polarity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of establishment of T-cell polarity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of establishment of T-lymphocyte polarity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of T cell polarization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of T lymphocyte polarization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of T-cell polarization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of establishment of T cell polarity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of establishment of T lymphocyte polarity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of establishment of T-cell polarity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of establishment of T-lymphocyte polarity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of T cell polarization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of T lymphocyte polarization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of T-cell polarization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of establishment of T cell polarity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of establishment of T lymphocyte polarity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of establishment of T-cell polarity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of establishment of T-lymphocyte polarity") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903905") -AnnotationAssertion(rdfs:label "positive regulation of establishment of T cell polarity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (primary palate development) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mgi_curators") Annotation( "GO_REF:0000094") Annotation( "PMID:24644145") Annotation( "PMID:25504820") "The process whose specific outcome is the progression of a primary palate over time, from its formation to the mature structure.") -AnnotationAssertion( "cls") -AnnotationAssertion( "2015-02-11T22:42:38Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "primary palate process development") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "palatum primarium development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "primitive palate development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "processus palatinus medianus development") -AnnotationAssertion( "GO:1903929") -AnnotationAssertion(rdfs:label "primary palate development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of respiratory gaseous exchange) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:22819705") "Any process that stops, prevents or reduces the frequency, rate or extent of respiratory gaseous exchange.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-02-17T20:26:24Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of respiratory gaseous exchange") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of respiratory gaseous exchange") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of respiratory gaseous exchange") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of respiratory gaseous exchange") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903941") -AnnotationAssertion(rdfs:label "negative regulation of respiratory gaseous exchange") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of respiratory gaseous exchange) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:22819705") "Any process that activates or increases the frequency, rate or extent of respiratory gaseous exchange.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-02-17T20:26:35Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of respiratory gaseous exchange") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of respiratory gaseous exchange") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of respiratory gaseous exchange") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of respiratory gaseous exchange") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903942") -AnnotationAssertion(rdfs:label "positive regulation of respiratory gaseous exchange") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of hepatocyte apoptotic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:8649852") "Any process that modulates the frequency, rate or extent of hepatocyte apoptotic process.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-02-19T12:54:40Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of hepatocyte apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903943") -AnnotationAssertion(rdfs:label "regulation of hepatocyte apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of hepatocyte apoptotic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:8649852") "Any process that stops, prevents or reduces the frequency, rate or extent of hepatocyte apoptotic process.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-02-19T12:54:50Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of hepatocyte apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of hepatocyte apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of hepatocyte apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of hepatocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of hepatocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of hepatocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of hepatocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of hepatocyte apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of hepatocyte apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903944") -AnnotationAssertion(rdfs:label "negative regulation of hepatocyte apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of hepatocyte apoptotic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:8649852") "Any process that activates or increases the frequency, rate or extent of hepatocyte apoptotic process.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-02-19T12:54:59Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of hepatocyte apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of hepatocyte apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of hepatocyte apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of hepatocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of hepatocyte apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of hepatocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of hepatocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of hepatocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of hepatocyte apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903945") -AnnotationAssertion(rdfs:label "positive regulation of hepatocyte apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of AV node cell action potential) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:mtg_cardiac_conduct_nov11") Annotation( "GOC:nc") Annotation( "GO_REF:0000058") Annotation( "PMID:25281747") "Any process that stops, prevents or reduces the frequency, rate or extent of AV node cell action potential.") -AnnotationAssertion( "nc") -AnnotationAssertion( "2015-02-20T14:59:41Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of AV node cardiac muscle cell action potential") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of AV node cell action potential") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of atrioventricular node cardiac muscle cell action potential") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of AV node cardiac muscle cell action potential") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of AV node cell action potential") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of atrioventricular node cardiac muscle cell action potential") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of AV node cardiac muscle cell action potential") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of AV node cell action potential") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of atrioventricular node cardiac muscle cell action potential") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of AV node cardiac muscle cell action potential") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of atrioventricular node cardiac muscle cell action potential") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of AV node cardiac muscle cell action potential") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of AV node cell action potential") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of atrioventricular node cardiac muscle cell action potential") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903950") -AnnotationAssertion(rdfs:label "negative regulation of AV node cell action potential") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of AV node cell action potential) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:mtg_cardiac_conduct_nov11") Annotation( "GOC:nc") Annotation( "GO_REF:0000058") Annotation( "PMID:25281747") "Any process that activates or increases the frequency, rate or extent of AV node cell action potential.") -AnnotationAssertion( "nc") -AnnotationAssertion( "2015-02-20T14:59:50Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of AV node cardiac muscle cell action potential") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of atrioventricular node cardiac muscle cell action potential") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of AV node cardiac muscle cell action potential") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of AV node cell action potential") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of atrioventricular node cardiac muscle cell action potential") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of AV node cardiac muscle cell action potential") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of AV node cell action potential") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of atrioventricular node cardiac muscle cell action potential") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of AV node cardiac muscle cell action potential") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of AV node cell action potential") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of atrioventricular node cardiac muscle cell action potential") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of AV node cardiac muscle cell action potential") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of AV node cell action potential") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of atrioventricular node cardiac muscle cell action potential") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903951") -AnnotationAssertion(rdfs:label "positive regulation of AV node cell action potential") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of glial cell migration) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:nc") Annotation( "GO_REF:0000058") Annotation( "PMID:19100238") "Any process that modulates the frequency, rate or extent of glial cell migration.") -AnnotationAssertion( "nc") -AnnotationAssertion( "2015-03-02T15:13:31Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of glia cell migration") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903975") -AnnotationAssertion(rdfs:label "regulation of glial cell migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of glial cell migration) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:nc") Annotation( "GO_REF:0000058") Annotation( "PMID:19100238") "Any process that stops, prevents or reduces the frequency, rate or extent of glial cell migration.") -AnnotationAssertion( "nc") -AnnotationAssertion( "2015-03-02T15:13:38Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of glia cell migration") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of glial cell migration") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of glia cell migration") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of glial cell migration") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of glia cell migration") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of glial cell migration") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of glia cell migration") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of glia cell migration") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of glial cell migration") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903976") -AnnotationAssertion(rdfs:label "negative regulation of glial cell migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of glial cell migration) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:nc") Annotation( "GO_REF:0000058") Annotation( "PMID:19100238") "Any process that activates or increases the frequency, rate or extent of glial cell migration.") -AnnotationAssertion( "nc") -AnnotationAssertion( "2015-03-02T15:13:43Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of glia cell migration") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of glia cell migration") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of glial cell migration") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of glia cell migration") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of glial cell migration") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of glia cell migration") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of glial cell migration") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of glia cell migration") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of glial cell migration") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1903977") -AnnotationAssertion(rdfs:label "positive regulation of glial cell migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (iron ion export across plasma membrane) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:kom") Annotation( "GOC:rl") Annotation( "GO_REF:0000074") Annotation( "PMID:15514116") "The directed movement of iron ions from inside of a cell, across the plasma membrane and into the extracellular region.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2014-09-03T13:01:37Z") -AnnotationAssertion( "GO:1903414") -AnnotationAssertion( "ferrous iron export") -AnnotationAssertion( "ferrous iron export across plasma membrane") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "iron cation export") -AnnotationAssertion( "iron(2+) export") -AnnotationAssertion( "GO:1903988") -AnnotationAssertion(rdfs:comment "An example of this is mouse ferroportin (symbol Slc40a1, UniProtKB identifier: Q9JHI9).") -AnnotationAssertion(rdfs:label "iron ion export across plasma membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (regulation of sebum secreting cell proliferation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:hjd") Annotation( "GO_REF:0000058") Annotation( "PMID:16901790") "Any process that modulates the frequency, rate or extent of sebum secreting cell proliferation.") -AnnotationAssertion( "hjd") -AnnotationAssertion( "2015-03-06T16:19:44Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of sebocyte proliferation") -AnnotationAssertion( "GO:1904002") -AnnotationAssertion(rdfs:label "regulation of sebum secreting cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of sebum secreting cell proliferation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:hjd") Annotation( "GO_REF:0000058") Annotation( "PMID:16901790") "Any process that stops, prevents or reduces the frequency, rate or extent of sebum secreting cell proliferation.") -AnnotationAssertion( "hjd") -AnnotationAssertion( "2015-03-06T16:19:50Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of sebum secreting cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of sebum secreting cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of sebum secreting cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of sebum secreting cell proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of sebocyte proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of sebocyte proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of sebocyte proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of sebocyte proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of sebocyte proliferation") -AnnotationAssertion( "GO:1904003") -AnnotationAssertion(rdfs:label "negative regulation of sebum secreting cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of sebum secreting cell proliferation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:hjd") Annotation( "GO_REF:0000058") Annotation( "PMID:16901790") "Any process that activates or increases the frequency, rate or extent of sebum secreting cell proliferation.") -AnnotationAssertion( "hjd") -AnnotationAssertion( "2015-03-06T16:19:56Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of sebum secreting cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of sebum secreting cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of sebum secreting cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of sebum secreting cell proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of sebocyte proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of sebocyte proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of sebocyte proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of sebocyte proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of sebocyte proliferation") -AnnotationAssertion( "GO:1904004") -AnnotationAssertion(rdfs:label "positive regulation of sebum secreting cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (response to serotonin) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000071") Annotation( "PMID:1505525") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a serotonin stimulus.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-03-06T19:33:54Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904014") -AnnotationAssertion(rdfs:label "response to serotonin") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cellular response to serotonin) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000071") Annotation( "PMID:1505525") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a serotonin stimulus.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-03-06T19:34:00Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904015") -AnnotationAssertion(rdfs:label "cellular response to serotonin") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of vasculature development) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:21472453") "Any process that activates or increases the frequency, rate or extent of vasculature development.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-03-06T22:17:04Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of vasculature development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of vasculature development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of vasculature development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of vasculature development") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of vascular system development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of vascular system development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of vascular system development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of vascular system development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of vascular system development") -AnnotationAssertion( "GO:1904018") -AnnotationAssertion(rdfs:label "positive regulation of vasculature development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (epithelial cell apoptotic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000085") Annotation( "PMID:19137015") "Any apoptotic process in an epithelial cell.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-03-06T22:27:17Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "epitheliocyte apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "epithelial cell apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "epitheliocyte apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904019") -AnnotationAssertion(rdfs:label "epithelial cell apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) -SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) -SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) -DisjointClasses( ObjectSomeValuesFrom( )) -DisjointClasses( ObjectSomeValuesFrom( )) - -# Class: (regulation of collagen fibril organization) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:25451920") "Any process that modulates the frequency, rate or extent of collagen fibril organization.") -AnnotationAssertion( "ae") -AnnotationAssertion( "2015-03-12T12:36:52Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of collagen fibril organisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of fibrillar collagen organization") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "regulation of collagen fibrillogenesis") -AnnotationAssertion( "GO:1904026") -AnnotationAssertion(rdfs:label "regulation of collagen fibril organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of collagen fibril organization) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:25451920") "Any process that stops, prevents or reduces the frequency, rate or extent of collagen fibril organization.") -AnnotationAssertion( "ae") -AnnotationAssertion( "2015-03-12T12:36:59Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of collagen fibril organisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of collagen fibril organization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of fibrillar collagen organization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of collagen fibril organisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of collagen fibril organization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of fibrillar collagen organization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of collagen fibril organisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of collagen fibril organization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of fibrillar collagen organization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of collagen fibril organisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of fibrillar collagen organization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of collagen fibril organisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of collagen fibril organization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of fibrillar collagen organization") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904027") -AnnotationAssertion(rdfs:label "negative regulation of collagen fibril organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of collagen fibril organization) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:25451920") "Any process that activates or increases the frequency, rate or extent of collagen fibril organization.") -AnnotationAssertion( "ae") -AnnotationAssertion( "2015-03-12T12:37:06Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of collagen fibril organisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of fibrillar collagen organization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of collagen fibril organisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of collagen fibril organization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of fibrillar collagen organization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of collagen fibril organisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of collagen fibril organization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of fibrillar collagen organization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of collagen fibril organisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of collagen fibril organization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of fibrillar collagen organization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of collagen fibril organisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of collagen fibril organization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of fibrillar collagen organization") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904028") -AnnotationAssertion(rdfs:label "positive regulation of collagen fibril organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of epithelial cell apoptotic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:19137015") "Any process that modulates the frequency, rate or extent of epithelial cell apoptotic process.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-03-13T22:05:41Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of epitheliocyte apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of epithelial cell apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of epitheliocyte apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904035") -AnnotationAssertion(rdfs:label "regulation of epithelial cell apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of epithelial cell apoptotic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:19137015") "Any process that stops, prevents or reduces the frequency, rate or extent of epithelial cell apoptotic process.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-03-13T22:05:47Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of epithelial cell apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of epitheliocyte apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of epithelial cell apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of epitheliocyte apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of epithelial cell apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of epitheliocyte apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of epitheliocyte apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of epithelial cell apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of epitheliocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of epithelial cell apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of epitheliocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of epithelial cell apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of epitheliocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of epithelial cell apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of epithelial cell apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of epitheliocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of epitheliocyte apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of epithelial cell apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of epitheliocyte apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904036") -AnnotationAssertion(rdfs:label "negative regulation of epithelial cell apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of epithelial cell apoptotic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:19137015") "Any process that activates or increases the frequency, rate or extent of epithelial cell apoptotic process.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-03-13T22:05:53Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of epitheliocyte apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of epithelial cell apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of epitheliocyte apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of epithelial cell apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of epitheliocyte apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of epithelial cell apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of epitheliocyte apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of epithelial cell apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of epithelial cell apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of epitheliocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of epitheliocyte apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of epithelial cell apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of epitheliocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of epithelial cell apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of epitheliocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of epithelial cell apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of epitheliocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of epithelial cell apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of epitheliocyte apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904037") -AnnotationAssertion(rdfs:label "positive regulation of epithelial cell apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of iron export across plasma membrane) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:kom") Annotation( "GO_REF:0000058") Annotation( "PMID:15514116") "Any process that modulates the frequency, rate or extent of export of iron ions from inside of a cell, across the plasma membrane and into the extracellular region.") -AnnotationAssertion( "kom") -AnnotationAssertion( "2015-03-16T15:36:37Z") -AnnotationAssertion( "regulation of ferrous iron export") -AnnotationAssertion( "regulation of iron(2+) export") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904038") -AnnotationAssertion(rdfs:label "regulation of iron export across plasma membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of iron export across plasma membrane) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:kom") Annotation( "GO_REF:0000058") Annotation( "PMID:15514116") "Any process that stops, prevents or reduces the frequency, rate or extent of export of iron ions from inside of a cell, across the plasma membrane and into the extracellular region.") -AnnotationAssertion( "kom") -AnnotationAssertion( "2015-03-16T15:36:43Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of ferrous iron export") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of iron(2+) export") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of ferrous iron export") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of iron(2+) export") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of ferrous iron export") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of iron(2+) export") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of ferrous iron export") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of iron(2+) export") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of ferrous iron export") -AnnotationAssertion( "negative regulation of iron(2+) export") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904039") -AnnotationAssertion(rdfs:label "negative regulation of iron export across plasma membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of iron export across plasma membrane) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:kom") Annotation( "GO_REF:0000058") Annotation( "PMID:15514116") "Any process that activates or increases the frequency, rate or extent of export of iron ions from inside of a cell, across the plasma membrane and into the extracellular region.") -AnnotationAssertion( "kom") -AnnotationAssertion( "2015-03-16T15:36:49Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of ferrous iron export") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of iron(2+) export") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of ferrous iron export") -AnnotationAssertion( "positive regulation of iron(2+) export") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of ferrous iron export") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of iron(2+) export") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of ferrous iron export") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of iron(2+) export") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of ferrous iron export") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of iron(2+) export") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904040") -AnnotationAssertion(rdfs:label "positive regulation of iron export across plasma membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (response to aldosterone) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000071") Annotation( "PMID:17644563") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aldosterone stimulus.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-03-16T23:07:53Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904044") -AnnotationAssertion(rdfs:label "response to aldosterone") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cellular response to aldosterone) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000071") Annotation( "PMID:17644563") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aldosterone stimulus.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-03-16T23:07:59Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904045") -AnnotationAssertion(rdfs:label "cellular response to aldosterone") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of cholangiocyte proliferation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:24434010") "Any process that modulates the frequency, rate or extent of cholangiocyte proliferation.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-03-18T17:56:14Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of hepatoblast proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904054") -AnnotationAssertion(rdfs:label "regulation of cholangiocyte proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of cholangiocyte proliferation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:24434010") "Any process that stops, prevents or reduces the frequency, rate or extent of cholangiocyte proliferation.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-03-18T17:56:20Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of cholangiocyte proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of hepatoblast proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of cholangiocyte proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of hepatoblast proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of cholangiocyte proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of hepatoblast proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of hepatoblast proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of cholangiocyte proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of hepatoblast proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904055") -AnnotationAssertion(rdfs:label "negative regulation of cholangiocyte proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of cholangiocyte proliferation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:24434010") "Any process that activates or increases the frequency, rate or extent of cholangiocyte proliferation.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-03-18T17:56:26Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of hepatoblast proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of cholangiocyte proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of hepatoblast proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of cholangiocyte proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of hepatoblast proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of cholangiocyte proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of hepatoblast proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of cholangiocyte proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of hepatoblast proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904056") -AnnotationAssertion(rdfs:label "positive regulation of cholangiocyte proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of sensory perception of pain) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:17167094") "Any process that stops, prevents or reduces the frequency, rate or extent of sensory perception of pain.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-03-18T20:33:57Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of nociception") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of sensory perception of pain") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of nociception") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of sensory perception of pain") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of nociception") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of sensory perception of pain") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of nociception") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of perception of physiological pain") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of perception of physiological pain") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of perception of physiological pain") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of nociception") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of perception of physiological pain") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of sensory perception of pain") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of perception of physiological pain") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904057") -AnnotationAssertion(rdfs:label "negative regulation of sensory perception of pain") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of sensory perception of pain) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:17167094") "Any process that activates or increases the frequency, rate or extent of sensory perception of pain.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-03-18T20:34:03Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of nociception") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of nociception") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of sensory perception of pain") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of nociception") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of sensory perception of pain") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of nociception") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of sensory perception of pain") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of nociception") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of perception of physiological pain") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of sensory perception of pain") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of perception of physiological pain") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of perception of physiological pain") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of perception of physiological pain") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of perception of physiological pain") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904058") -AnnotationAssertion(rdfs:label "positive regulation of sensory perception of pain") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of monoatomic cation transmembrane transport) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:15304482") "Any process that modulates the frequency, rate or extent of cation transmembrane transport.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-03-18T21:11:43Z") -AnnotationAssertion( "regulation of cation transmembrane transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904062") -AnnotationAssertion(rdfs:label "regulation of monoatomic cation transmembrane transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of cation transmembrane transport) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:15304482") "Any process that stops, prevents or reduces the frequency, rate or extent of cation transmembrane transport.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-03-18T21:11:50Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of cation transmembrane transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of cation transmembrane transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of cation transmembrane transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of cation transmembrane transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904063") -AnnotationAssertion(rdfs:label "negative regulation of cation transmembrane transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of cation transmembrane transport) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:15304482") "Any process that activates or increases the frequency, rate or extent of cation transmembrane transport.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-03-18T21:11:55Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of cation transmembrane transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of cation transmembrane transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of cation transmembrane transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of cation transmembrane transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904064") -AnnotationAssertion(rdfs:label "positive regulation of cation transmembrane transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (G protein-coupled acetylcholine receptor signaling pathway involved in positive regulation of acetylcholine secretion, neurotransmission) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:kmv") Annotation( "GO_REF:0000060") Annotation( "PMID:22588719") "Any G protein-coupled acetylcholine receptor signaling pathway that is involved in positive regulation of acetylcholine secretion, neurotransmission.") -AnnotationAssertion( "kmv") -AnnotationAssertion( "2015-03-19T15:28:47Z") -AnnotationAssertion( "G-protein coupled acetylcholine receptor signaling pathway involved in positive regulation of acetylcholine secretion, neurotransmission") -AnnotationAssertion(Annotation( "GOC:TermGenie") "G-protein coupled acetylcholine receptor signaling pathway involved in up regulation of acetylcholine secretion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "G-protein coupled acetylcholine receptor signaling pathway involved in up-regulation of acetylcholine secretion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "G-protein coupled acetylcholine receptor signaling pathway involved in upregulation of acetylcholine secretion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "acetylcholine receptor signalling, muscarinic pathway involved in positive regulation of acetylcholine secretion, neurotransmission") -AnnotationAssertion(Annotation( "GOC:TermGenie") "acetylcholine receptor signalling, muscarinic pathway involved in up regulation of acetylcholine secretion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "acetylcholine receptor signalling, muscarinic pathway involved in up-regulation of acetylcholine secretion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "acetylcholine receptor signalling, muscarinic pathway involved in upregulation of acetylcholine secretion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "muscarinic acetylcholine receptor signaling pathway involved in positive regulation of acetylcholine secretion, neurotransmission") -AnnotationAssertion(Annotation( "GOC:TermGenie") "muscarinic acetylcholine receptor signaling pathway involved in up regulation of acetylcholine secretion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "muscarinic acetylcholine receptor signaling pathway involved in up-regulation of acetylcholine secretion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "muscarinic acetylcholine receptor signaling pathway involved in upregulation of acetylcholine secretion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "G-protein coupled acetylcholine receptor signaling pathway involved in activation of acetylcholine secretion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "G-protein coupled acetylcholine receptor signaling pathway involved in stimulation of acetylcholine secretion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "acetylcholine receptor signalling, muscarinic pathway involved in activation of acetylcholine secretion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "acetylcholine receptor signalling, muscarinic pathway involved in stimulation of acetylcholine secretion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "muscarinic acetylcholine receptor signaling pathway involved in activation of acetylcholine secretion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "muscarinic acetylcholine receptor signaling pathway involved in stimulation of acetylcholine secretion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904065") -AnnotationAssertion(rdfs:label "G protein-coupled acetylcholine receptor signaling pathway involved in positive regulation of acetylcholine secretion, neurotransmission") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of trophectodermal cell proliferation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:24508636") "Any process that modulates the frequency, rate or extent of trophectodermal cell proliferation.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2015-03-20T16:55:56Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of trophectoderm cell proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904073") -AnnotationAssertion(rdfs:label "regulation of trophectodermal cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (negative regulation of trophectodermal cell proliferation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:24508636") "Any process that stops, prevents or reduces the frequency, rate or extent of trophectodermal cell proliferation.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2015-03-20T16:56:02Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of trophectoderm cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of trophectodermal cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of trophectoderm cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of trophectodermal cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of trophectoderm cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of trophectodermal cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of trophectoderm cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of trophectoderm cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of trophectodermal cell proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904074") -AnnotationAssertion(rdfs:label "negative regulation of trophectodermal cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of trophectodermal cell proliferation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:24508636") "Any process that activates or increases the frequency, rate or extent of trophectodermal cell proliferation.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2015-03-20T16:56:08Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of trophectoderm cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of trophectoderm cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of trophectodermal cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of trophectoderm cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of trophectodermal cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of trophectoderm cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of trophectodermal cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of trophectoderm cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of trophectodermal cell proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904075") -AnnotationAssertion(rdfs:label "positive regulation of trophectodermal cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (protein localization to microvillus) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:kmv") Annotation( "GO_REF:0000087") Annotation( "PMID:25335890") "A process in which a protein is transported to, or maintained in, a location within a microvillus.") -AnnotationAssertion( "kmv") -AnnotationAssertion( "2015-04-01T18:14:41Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "protein localisation in microvillus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "protein localisation to microvillus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "protein localization in microvillus") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904106") -AnnotationAssertion(rdfs:label "protein localization to microvillus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (axon cytoplasm) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000064") Annotation( "PMID:18667152") "Any cytoplasm that is part of a axon.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/14472"^^xsd:anyURI) -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-04-06T18:13:14Z") -AnnotationAssertion( "axoplasm") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:1904115") -AnnotationAssertion(rdfs:label "axon cytoplasm") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (response to vasopressin) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000071") Annotation( "PMID:22811487") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vasopressin stimulus.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-04-06T19:39:42Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904116") -AnnotationAssertion(rdfs:label "response to vasopressin") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cellular response to vasopressin) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000071") Annotation( "PMID:22811487") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vasopressin stimulus.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-04-06T19:39:48Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904117") -AnnotationAssertion(rdfs:label "cellular response to vasopressin") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of otic vesicle morphogenesis) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:25677106") "Any process that modulates the frequency, rate or extent of otic vesicle morphogenesis.") -AnnotationAssertion( "pga") -AnnotationAssertion( "2015-04-07T14:00:56Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904118") -AnnotationAssertion(rdfs:label "regulation of otic vesicle morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of otic vesicle morphogenesis) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:25677106") "Any process that stops, prevents or reduces the frequency, rate or extent of otic vesicle morphogenesis.") -AnnotationAssertion( "pga") -AnnotationAssertion( "2015-04-07T14:01:02Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of otic vesicle morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of otic vesicle morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of otic vesicle morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of otic vesicle morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904119") -AnnotationAssertion(rdfs:label "negative regulation of otic vesicle morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of otic vesicle morphogenesis) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:25677106") "Any process that activates or increases the frequency, rate or extent of otic vesicle morphogenesis.") -AnnotationAssertion( "pga") -AnnotationAssertion( "2015-04-07T14:01:08Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of otic vesicle morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of otic vesicle morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of otic vesicle morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of otic vesicle morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904120") -AnnotationAssertion(rdfs:label "positive regulation of otic vesicle morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of carotenoid biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:25675505") "Any process that stops, prevents or reduces the frequency, rate or extent of carotenoid biosynthetic process.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2015-04-13T19:39:13Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of carotenoid anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of carotenoid biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of carotenoid biosynthetic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of carotenoid formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of carotenoid synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of carotenoid anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of carotenoid biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of carotenoid biosynthetic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of carotenoid formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of carotenoid synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of carotenoid anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of carotenoid biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of carotenoid biosynthetic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of carotenoid formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of carotenoid synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of carotenoid anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of carotenoid biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of carotenoid formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of carotenoid synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of carotenoid anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of carotenoid biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of carotenoid biosynthetic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of carotenoid formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of carotenoid synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904142") -AnnotationAssertion(rdfs:label "negative regulation of carotenoid biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of carotenoid biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:25675505") "Any process that activates or increases the frequency, rate or extent of carotenoid biosynthetic process.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2015-04-13T19:39:19Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of carotenoid anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of carotenoid biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of carotenoid formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of carotenoid synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of carotenoid anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of carotenoid biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of carotenoid biosynthetic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of carotenoid formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of carotenoid synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of carotenoid anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of carotenoid biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of carotenoid biosynthetic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of carotenoid formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of carotenoid synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of carotenoid anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of carotenoid biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of carotenoid biosynthetic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of carotenoid formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of carotenoid synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of carotenoid anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of carotenoid biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of carotenoid biosynthetic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of carotenoid formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of carotenoid synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904143") -AnnotationAssertion(rdfs:label "positive regulation of carotenoid biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of meiotic cell cycle process involved in oocyte maturation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:22674394") "Any process that stops, prevents or reduces the frequency, rate or extent of meiotic cell cycle process involved in oocyte maturation.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2015-04-14T15:59:22Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of meiotic cell cycle process involved in oocyte maturation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of meiotic cell cycle process involved in oocyte maturation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of meiotic cell cycle process involved in oocyte maturation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of meiotic cell cycle process involved in oocyte maturation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904145") -AnnotationAssertion(rdfs:label "negative regulation of meiotic cell cycle process involved in oocyte maturation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of meiotic cell cycle process involved in oocyte maturation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:22674394") "Any process that activates or increases the frequency, rate or extent of meiotic cell cycle process involved in oocyte maturation.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2015-04-14T15:59:28Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of meiotic cell cycle process involved in oocyte maturation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of meiotic cell cycle process involved in oocyte maturation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of meiotic cell cycle process involved in oocyte maturation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of meiotic cell cycle process involved in oocyte maturation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904146") -AnnotationAssertion(rdfs:label "positive regulation of meiotic cell cycle process involved in oocyte maturation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (regulation of bleb assembly) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:als") Annotation( "GO_REF:0000058") Annotation( "PMID:25651887") "Any process that modulates the frequency, rate or extent of bleb assembly.") -AnnotationAssertion( "als") -AnnotationAssertion( "2015-04-23T09:32:19Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of cell blebbing") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904170") -AnnotationAssertion(rdfs:label "regulation of bleb assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of bleb assembly) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:als") Annotation( "GO_REF:0000058") Annotation( "PMID:25651887") "Any process that stops, prevents or reduces the frequency, rate or extent of bleb assembly.") -AnnotationAssertion( "als") -AnnotationAssertion( "2015-04-23T09:32:25Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of bleb assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of cell blebbing") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of bleb assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of cell blebbing") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of bleb assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of cell blebbing") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of cell blebbing") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of bleb assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of cell blebbing") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904171") -AnnotationAssertion(rdfs:label "negative regulation of bleb assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of bleb assembly) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:als") Annotation( "GO_REF:0000058") Annotation( "PMID:25651887") "Any process that activates or increases the frequency, rate or extent of bleb assembly.") -AnnotationAssertion( "als") -AnnotationAssertion( "2015-04-23T09:32:31Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of cell blebbing") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of bleb assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of cell blebbing") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of bleb assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of cell blebbing") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of bleb assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of cell blebbing") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of bleb assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of cell blebbing") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904172") -AnnotationAssertion(rdfs:label "positive regulation of bleb assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of adipose tissue development) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:23081848") "Any process that modulates the frequency, rate or extent of adipose tissue development.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-04-29T20:01:01Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of adipogenesis") -AnnotationAssertion( "GO:1904177") -AnnotationAssertion(rdfs:label "regulation of adipose tissue development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of adipose tissue development) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:23081848") "Any process that stops, prevents or reduces the frequency, rate or extent of adipose tissue development.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-04-29T20:01:07Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of adipose tissue development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of adipose tissue development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of adipose tissue development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of adipose tissue development") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of adipogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of adipogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of adipogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of adipogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of adipogenesis") -AnnotationAssertion( "GO:1904178") -AnnotationAssertion(rdfs:label "negative regulation of adipose tissue development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of adipose tissue development) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:23081848") "Any process that activates or increases the frequency, rate or extent of adipose tissue development.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-04-29T20:01:13Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of adipose tissue development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of adipose tissue development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of adipose tissue development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of adipose tissue development") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of adipogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of adipogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of adipogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of adipogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of adipogenesis") -AnnotationAssertion( "GO:1904179") -AnnotationAssertion(rdfs:label "positive regulation of adipose tissue development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (regulation of cholangiocyte apoptotic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:24498161") "Any process that modulates the frequency, rate or extent of cholangiocyte apoptotic process.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-05-06T15:25:48Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of epithelial cell of bile duct apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of cholangiocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of epithelial cell of bile duct apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904192") -AnnotationAssertion(rdfs:label "regulation of cholangiocyte apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of cholangiocyte apoptotic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:24498161") "Any process that stops, prevents or reduces the frequency, rate or extent of cholangiocyte apoptotic process.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-05-06T15:25:55Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of cholangiocyte apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of epithelial cell of bile duct apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of cholangiocyte apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of epithelial cell of bile duct apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of cholangiocyte apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of epithelial cell of bile duct apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of epithelial cell of bile duct apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of cholangiocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of epithelial cell of bile duct apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of cholangiocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of epithelial cell of bile duct apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of cholangiocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of epithelial cell of bile duct apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of cholangiocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of cholangiocyte apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of epithelial cell of bile duct apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of epithelial cell of bile duct apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of cholangiocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of epithelial cell of bile duct apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904193") -AnnotationAssertion(rdfs:label "negative regulation of cholangiocyte apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of cholangiocyte apoptotic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:24498161") "Any process that activates or increases the frequency, rate or extent of cholangiocyte apoptotic process.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-05-06T15:26:00Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of epithelial cell of bile duct apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of cholangiocyte apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of epithelial cell of bile duct apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of cholangiocyte apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of epithelial cell of bile duct apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of cholangiocyte apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of epithelial cell of bile duct apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of cholangiocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of cholangiocyte apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of epithelial cell of bile duct apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of epithelial cell of bile duct apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of cholangiocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of epithelial cell of bile duct apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of cholangiocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of epithelial cell of bile duct apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of cholangiocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of epithelial cell of bile duct apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of cholangiocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of epithelial cell of bile duct apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904194") -AnnotationAssertion(rdfs:label "positive regulation of cholangiocyte apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of granulosa cell proliferation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:22383759") "Any process that modulates the frequency, rate or extent of granulosa cell proliferation.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-05-07T17:02:25Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904195") -AnnotationAssertion(rdfs:label "regulation of granulosa cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of granulosa cell proliferation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:22383759") "Any process that stops, prevents or reduces the frequency, rate or extent of granulosa cell proliferation.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-05-07T17:02:34Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of granulosa cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of granulosa cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of granulosa cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of granulosa cell proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904196") -AnnotationAssertion(rdfs:label "negative regulation of granulosa cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of granulosa cell proliferation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:22383759") "Any process that activates or increases the frequency, rate or extent of granulosa cell proliferation.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-05-07T17:02:40Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of granulosa cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of granulosa cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of granulosa cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of granulosa cell proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904197") -AnnotationAssertion(rdfs:label "positive regulation of granulosa cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of skeletal muscle hypertrophy) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:23470307") "Any process that modulates the frequency, rate or extent of skeletal muscle hypertrophy.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-05-08T17:38:13Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904204") -AnnotationAssertion(rdfs:label "regulation of skeletal muscle hypertrophy") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of skeletal muscle hypertrophy) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:23470307") "Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle hypertrophy.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-05-08T17:38:19Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of skeletal muscle hypertrophy") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of skeletal muscle hypertrophy") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of skeletal muscle hypertrophy") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of skeletal muscle hypertrophy") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904205") -AnnotationAssertion(rdfs:label "negative regulation of skeletal muscle hypertrophy") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of skeletal muscle hypertrophy) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:23470307") "Any process that activates or increases the frequency, rate or extent of skeletal muscle hypertrophy.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-05-08T17:38:25Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of skeletal muscle hypertrophy") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of skeletal muscle hypertrophy") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of skeletal muscle hypertrophy") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of skeletal muscle hypertrophy") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904206") -AnnotationAssertion(rdfs:label "positive regulation of skeletal muscle hypertrophy") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (pericyte cell differentiation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:dph") Annotation( "GO_REF:0000086") Annotation( "PMID:23868830") "The process in which a relatively unspecialized cell acquires the specialized features of a pericyte cell.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2015-05-15T14:50:13Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904238") -AnnotationAssertion(rdfs:label "pericyte cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of bile acid metabolic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:bf") Annotation( "GO_REF:0000058") "Any process that modulates the frequency, rate or extent of bile acid metabolic process.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2015-05-20T11:04:28Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of bile acid metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904251") -AnnotationAssertion(rdfs:label "regulation of bile acid metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of bile acid metabolic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:bf") Annotation( "GO_REF:0000058") "Any process that stops, prevents or reduces the frequency, rate or extent of bile acid metabolic process.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2015-05-20T11:04:35Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of bile acid metabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of bile acid metabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of bile acid metabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of bile acid metabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of bile acid metabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of bile acid metabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of bile acid metabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of bile acid metabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of bile acid metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904252") -AnnotationAssertion(rdfs:label "negative regulation of bile acid metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of bile acid metabolic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:bf") Annotation( "GO_REF:0000058") "Any process that activates or increases the frequency, rate or extent of bile acid metabolic process.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2015-05-20T11:04:40Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of bile acid metabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of bile acid metabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of bile acid metabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of bile acid metabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of bile acid metabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of bile acid metabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of bile acid metabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of bile acid metabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of bile acid metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904253") -AnnotationAssertion(rdfs:label "positive regulation of bile acid metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of iron ion transmembrane transporter activity) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:kom") Annotation( "GO_REF:0000059") Annotation( "PMID:15514116") "Any process that modulates the frequency, rate or extent of an iron transmembrane transporter activity.") -AnnotationAssertion( "kom") -AnnotationAssertion( "2015-05-20T14:05:00Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of iron cation channel activity") -AnnotationAssertion( "regulation of iron channel activity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of iron-specific channel activity") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904254") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "regulation of iron ion transmembrane transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (negative regulation of iron ion transmembrane transporter activity) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:kom") Annotation( "GO_REF:0000059") Annotation( "PMID:15514116") "Any process that stops, prevents or reduces the frequency, rate or extent of an iron transmembrane transporter activity.") -AnnotationAssertion( "kom") -AnnotationAssertion( "2015-05-20T14:05:06Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of iron cation channel activity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of iron channel activity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of iron-specific channel activity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of iron cation channel activity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of iron channel activity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of iron-specific channel activity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of iron cation channel activity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of iron channel activity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of iron-specific channel activity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of iron cation channel activity") -AnnotationAssertion( "negative regulation of iron channel activity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of iron-specific channel activity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of iron cation channel activity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of iron channel activity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of iron-specific channel activity") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904255") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "negative regulation of iron ion transmembrane transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of iron ion transmembrane transporter activity) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:kom") Annotation( "GO_REF:0000059") Annotation( "PMID:15514116") "Any process that activates or increases the frequency, rate or extent of an iron transmembrane transporter activity.") -AnnotationAssertion( "kom") -AnnotationAssertion( "2015-05-20T14:05:12Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of iron cation channel activity") -AnnotationAssertion( "positive regulation of iron channel activity") -AnnotationAssertion( "positive regulation of iron transmembrane transporter activity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of iron-specific channel activity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of iron cation channel activity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of iron channel activity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of iron-specific channel activity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of iron cation channel activity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of iron channel activity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of iron-specific channel activity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of iron cation channel activity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of iron channel activity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of iron-specific channel activity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of iron cation channel activity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of iron channel activity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of iron-specific channel activity") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904256") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "positive regulation of iron ion transmembrane transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (regulation of Schwann cell chemotaxis) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:16203995") "Any process that modulates the frequency, rate or extent of Schwann cell chemotaxis.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-05-28T17:47:41Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904266") -AnnotationAssertion(rdfs:label "regulation of Schwann cell chemotaxis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of Schwann cell chemotaxis) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:16203995") "Any process that stops, prevents or reduces the frequency, rate or extent of Schwann cell chemotaxis.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-05-28T17:47:48Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of Schwann cell chemotaxis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of Schwann cell chemotaxis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of Schwann cell chemotaxis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of Schwann cell chemotaxis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904267") -AnnotationAssertion(rdfs:label "negative regulation of Schwann cell chemotaxis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of Schwann cell chemotaxis) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:16203995") "Any process that activates or increases the frequency, rate or extent of Schwann cell chemotaxis.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-05-28T17:47:55Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of Schwann cell chemotaxis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of Schwann cell chemotaxis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of Schwann cell chemotaxis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of Schwann cell chemotaxis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904268") -AnnotationAssertion(rdfs:label "positive regulation of Schwann cell chemotaxis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cell leading edge cell cortex) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:kmv") Annotation( "GO_REF:0000064") Annotation( "PMID:25843030") "The cell cortex of the leading edge of a cell.") -AnnotationAssertion( "kmv") -AnnotationAssertion( "2015-05-28T19:16:03Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "cell cortex of cell leading edge") -AnnotationAssertion(Annotation( "GOC:TermGenie") "cell cortex of front of cell") -AnnotationAssertion(Annotation( "GOC:TermGenie") "cell cortex of leading edge of cell") -AnnotationAssertion( "cellular_component") -AnnotationAssertion(Annotation( "GOC:TermGenie") "cell periphery of cell leading edge") -AnnotationAssertion(Annotation( "GOC:TermGenie") "cell periphery of front of cell") -AnnotationAssertion(Annotation( "GOC:TermGenie") "cell periphery of leading edge of cell") -AnnotationAssertion(Annotation( "GOC:TermGenie") "peripheral cytoplasm of cell leading edge") -AnnotationAssertion(Annotation( "GOC:TermGenie") "peripheral cytoplasm of front of cell") -AnnotationAssertion(Annotation( "GOC:TermGenie") "peripheral cytoplasm of leading edge of cell") -AnnotationAssertion( "GO:1904269") -AnnotationAssertion(rdfs:label "cell leading edge cell cortex") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of gastro-intestinal system smooth muscle contraction) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:10821044") "Any process that modulates the frequency, rate or extent of gastro-intestinal system smooth muscle contraction.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-06-09T23:18:42Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904304") -AnnotationAssertion(rdfs:label "regulation of gastro-intestinal system smooth muscle contraction") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of gastro-intestinal system smooth muscle contraction) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:10821044") "Any process that stops, prevents or reduces the frequency, rate or extent of gastro-intestinal system smooth muscle contraction.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-06-09T23:18:48Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of gastro-intestinal system smooth muscle contraction") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of gastro-intestinal system smooth muscle contraction") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of gastro-intestinal system smooth muscle contraction") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of gastro-intestinal system smooth muscle contraction") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904305") -AnnotationAssertion(rdfs:label "negative regulation of gastro-intestinal system smooth muscle contraction") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of gastro-intestinal system smooth muscle contraction) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:10821044") "Any process that activates or increases the frequency, rate or extent of gastro-intestinal system smooth muscle contraction.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-06-09T23:18:54Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of gastro-intestinal system smooth muscle contraction") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of gastro-intestinal system smooth muscle contraction") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of gastro-intestinal system smooth muscle contraction") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of gastro-intestinal system smooth muscle contraction") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904306") -AnnotationAssertion(rdfs:label "positive regulation of gastro-intestinal system smooth muscle contraction") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of smooth muscle contraction involved in micturition) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:18562635") "Any process that modulates the frequency, rate or extent of smooth muscle contraction involved in micturition.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-06-10T18:46:11Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of smooth muscle contraction involved in urination") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of urinary bladder smooth muscle contraction involved in micturition") -AnnotationAssertion( "GO:1904318") -AnnotationAssertion(rdfs:label "regulation of smooth muscle contraction involved in micturition") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of smooth muscle contraction involved in micturition) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:18562635") "Any process that stops, prevents or reduces the frequency, rate or extent of smooth muscle contraction involved in micturition.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-06-10T18:46:17Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of smooth muscle contraction involved in micturition") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of smooth muscle contraction involved in micturition") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of smooth muscle contraction involved in micturition") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of smooth muscle contraction involved in micturition") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of smooth muscle contraction involved in urination") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of urinary bladder smooth muscle contraction involved in micturition") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of smooth muscle contraction involved in urination") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of urinary bladder smooth muscle contraction involved in micturition") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of smooth muscle contraction involved in urination") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of urinary bladder smooth muscle contraction involved in micturition") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of smooth muscle contraction involved in urination") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of urinary bladder smooth muscle contraction involved in micturition") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of smooth muscle contraction involved in urination") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of urinary bladder smooth muscle contraction involved in micturition") -AnnotationAssertion( "GO:1904319") -AnnotationAssertion(rdfs:label "negative regulation of smooth muscle contraction involved in micturition") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of smooth muscle contraction involved in micturition) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:18562635") "Any process that activates or increases the frequency, rate or extent of smooth muscle contraction involved in micturition.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-06-10T18:46:23Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of smooth muscle contraction involved in micturition") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of smooth muscle contraction involved in micturition") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of smooth muscle contraction involved in micturition") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of smooth muscle contraction involved in micturition") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of smooth muscle contraction involved in urination") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of urinary bladder smooth muscle contraction involved in micturition") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of smooth muscle contraction involved in urination") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of urinary bladder smooth muscle contraction involved in micturition") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of smooth muscle contraction involved in urination") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of urinary bladder smooth muscle contraction involved in micturition") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of smooth muscle contraction involved in urination") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of urinary bladder smooth muscle contraction involved in micturition") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of smooth muscle contraction involved in urination") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of urinary bladder smooth muscle contraction involved in micturition") -AnnotationAssertion( "GO:1904320") -AnnotationAssertion(rdfs:label "positive regulation of smooth muscle contraction involved in micturition") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of dopaminergic neuron differentiation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:15522889") "Any process that modulates the frequency, rate or extent of dopaminergic neuron differentiation.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-06-11T18:06:19Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904338") -AnnotationAssertion(rdfs:label "regulation of dopaminergic neuron differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of dopaminergic neuron differentiation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:15522889") "Any process that stops, prevents or reduces the frequency, rate or extent of dopaminergic neuron differentiation.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-06-11T18:06:25Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of dopaminergic neuron differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of dopaminergic neuron differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of dopaminergic neuron differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of dopaminergic neuron differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904339") -AnnotationAssertion(rdfs:label "negative regulation of dopaminergic neuron differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of dopaminergic neuron differentiation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:15522889") "Any process that activates or increases the frequency, rate or extent of dopaminergic neuron differentiation.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-06-11T18:06:32Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of dopaminergic neuron differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of dopaminergic neuron differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of dopaminergic neuron differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of dopaminergic neuron differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904340") -AnnotationAssertion(rdfs:label "positive regulation of dopaminergic neuron differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of colon smooth muscle contraction) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:24170253") "Any process that modulates the frequency, rate or extent of colon smooth muscle contraction.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-06-11T21:16:58Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904341") -AnnotationAssertion(rdfs:label "regulation of colon smooth muscle contraction") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (negative regulation of colon smooth muscle contraction) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:24170253") "Any process that stops, prevents or reduces the frequency, rate or extent of colon smooth muscle contraction.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-06-11T21:17:05Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of colon smooth muscle contraction") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of colon smooth muscle contraction") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of colon smooth muscle contraction") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of colon smooth muscle contraction") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904342") -AnnotationAssertion(rdfs:label "negative regulation of colon smooth muscle contraction") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of colon smooth muscle contraction) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:24170253") "Any process that activates or increases the frequency, rate or extent of colon smooth muscle contraction.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-06-11T21:17:11Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of colon smooth muscle contraction") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of colon smooth muscle contraction") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of colon smooth muscle contraction") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of colon smooth muscle contraction") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904343") -AnnotationAssertion(rdfs:label "positive regulation of colon smooth muscle contraction") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (regulation of gastric mucosal blood circulation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:10807413") "Any process that modulates the frequency, rate or extent of gastric mucosal blood circulation.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-06-11T21:20:31Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of stomach mucosal blood circulation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904344") -AnnotationAssertion(rdfs:label "regulation of gastric mucosal blood circulation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of gastric mucosal blood circulation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:10807413") "Any process that stops, prevents or reduces the frequency, rate or extent of gastric mucosal blood circulation.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-06-11T21:20:44Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of gastric mucosal blood circulation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of stomach mucosal blood circulation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of gastric mucosal blood circulation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of stomach mucosal blood circulation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of gastric mucosal blood circulation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of stomach mucosal blood circulation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of stomach mucosal blood circulation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of gastric mucosal blood circulation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of stomach mucosal blood circulation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904345") -AnnotationAssertion(rdfs:label "negative regulation of gastric mucosal blood circulation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of gastric mucosal blood circulation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:10807413") "Any process that activates or increases the frequency, rate or extent of gastric mucosal blood circulation.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-06-11T21:20:50Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of stomach mucosal blood circulation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of gastric mucosal blood circulation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of stomach mucosal blood circulation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of gastric mucosal blood circulation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of stomach mucosal blood circulation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of gastric mucosal blood circulation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of stomach mucosal blood circulation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of gastric mucosal blood circulation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of stomach mucosal blood circulation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904346") -AnnotationAssertion(rdfs:label "positive regulation of gastric mucosal blood circulation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of small intestine smooth muscle contraction) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:11991626") "Any process that modulates the frequency, rate or extent of small intestine smooth muscle contraction.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-06-11T21:37:34Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904347") -AnnotationAssertion(rdfs:label "regulation of small intestine smooth muscle contraction") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (negative regulation of small intestine smooth muscle contraction) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:11991626") "Any process that stops, prevents or reduces the frequency, rate or extent of small intestine smooth muscle contraction.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-06-11T21:37:40Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of small intestine smooth muscle contraction") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of small intestine smooth muscle contraction") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of small intestine smooth muscle contraction") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of small intestine smooth muscle contraction") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904348") -AnnotationAssertion(rdfs:label "negative regulation of small intestine smooth muscle contraction") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of small intestine smooth muscle contraction) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:11991626") "Any process that activates or increases the frequency, rate or extent of small intestine smooth muscle contraction.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-06-11T21:37:46Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of small intestine smooth muscle contraction") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of small intestine smooth muscle contraction") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of small intestine smooth muscle contraction") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of small intestine smooth muscle contraction") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904349") -AnnotationAssertion(rdfs:label "positive regulation of small intestine smooth muscle contraction") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (regulation of protein catabolic process in the vacuole) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "GO_REF:0000058") Annotation( "PMID:25635054") "Any process that modulates the frequency, rate or extent of protein catabolic process in the vacuole.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2015-06-12T09:10:36Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of vacuolar protein breakdown") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of vacuolar protein catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of vacuolar protein catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of vacuolar protein degradation") -AnnotationAssertion( "GO:1904350") -AnnotationAssertion(rdfs:label "regulation of protein catabolic process in the vacuole") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of protein catabolic process in the vacuole) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "GO_REF:0000058") Annotation( "PMID:25635054") "Any process that stops, prevents or reduces the frequency, rate or extent of protein catabolic process in the vacuole.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2015-06-12T09:10:42Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of protein catabolic process in the vacuole") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of protein catabolic process in the vacuole") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of protein catabolic process in the vacuole") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of protein catabolic process in the vacuole") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of vacuolar protein breakdown") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of vacuolar protein catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of vacuolar protein catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of vacuolar protein degradation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of vacuolar protein breakdown") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of vacuolar protein catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of vacuolar protein catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of vacuolar protein degradation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of vacuolar protein breakdown") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of vacuolar protein catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of vacuolar protein catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of vacuolar protein degradation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of vacuolar protein breakdown") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of vacuolar protein catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of vacuolar protein catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of vacuolar protein degradation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of vacuolar protein breakdown") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of vacuolar protein catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of vacuolar protein catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of vacuolar protein degradation") -AnnotationAssertion( "GO:1904351") -AnnotationAssertion(rdfs:label "negative regulation of protein catabolic process in the vacuole") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of protein catabolic process in the vacuole) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "GO_REF:0000058") Annotation( "PMID:25635054") "Any process that activates or increases the frequency, rate or extent of protein catabolic process in the vacuole.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2015-06-12T09:10:49Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of protein catabolic process in the vacuole") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of protein catabolic process in the vacuole") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of protein catabolic process in the vacuole") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of protein catabolic process in the vacuole") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of vacuolar protein breakdown") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of vacuolar protein catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of vacuolar protein catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of vacuolar protein degradation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of vacuolar protein breakdown") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of vacuolar protein catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of vacuolar protein catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of vacuolar protein degradation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of vacuolar protein breakdown") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of vacuolar protein catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of vacuolar protein catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of vacuolar protein degradation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of vacuolar protein breakdown") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of vacuolar protein catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of vacuolar protein catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of vacuolar protein degradation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of vacuolar protein breakdown") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of vacuolar protein catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of vacuolar protein catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of vacuolar protein degradation") -AnnotationAssertion( "GO:1904352") -AnnotationAssertion(rdfs:label "positive regulation of protein catabolic process in the vacuole") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of calcitonin secretion) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:11278900") "Any process that modulates the frequency, rate or extent of calcitonin secretion.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-06-15T17:54:52Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904362") -AnnotationAssertion(rdfs:label "regulation of calcitonin secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (negative regulation of calcitonin secretion) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:11278900") "Any process that stops, prevents or reduces the frequency, rate or extent of calcitonin secretion.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-06-15T17:54:58Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of calcitonin secretion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of calcitonin secretion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of calcitonin secretion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of calcitonin secretion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904363") -AnnotationAssertion(rdfs:label "negative regulation of calcitonin secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of calcitonin secretion) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:11278900") "Any process that activates or increases the frequency, rate or extent of calcitonin secretion.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-06-15T17:55:05Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of calcitonin secretion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of calcitonin secretion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of calcitonin secretion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of calcitonin secretion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904364") -AnnotationAssertion(rdfs:label "positive regulation of calcitonin secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of protein localization to cell periphery) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:18216290") "Any process that modulates the frequency, rate or extent of protein localization to cell periphery.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-06-22T22:09:25Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904375") -AnnotationAssertion(rdfs:label "regulation of protein localization to cell periphery") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of protein localization to cell periphery) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:18216290") "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell periphery.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-06-22T22:09:32Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of protein localization to cell periphery") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of protein localization to cell periphery") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of protein localization to cell periphery") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of protein localization to cell periphery") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904376") -AnnotationAssertion(rdfs:label "negative regulation of protein localization to cell periphery") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of protein localization to cell periphery) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:18216290") "Any process that activates or increases the frequency, rate or extent of protein localization to cell periphery.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-06-22T22:09:37Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of protein localization to cell periphery") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of protein localization to cell periphery") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of protein localization to cell periphery") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of protein localization to cell periphery") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904377") -AnnotationAssertion(rdfs:label "positive regulation of protein localization to cell periphery") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cone retinal bipolar cell differentiation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000086") Annotation( "PMID:24123365") "The process in which a relatively unspecialized cell acquires the specialized features of a cone retinal bipolar cell.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-06-23T19:01:16Z") -AnnotationAssertion(Annotation( "PMID:14745032") "cone bipolar cell differentiation") -AnnotationAssertion( "retinal cone bipolar cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904390") -AnnotationAssertion(rdfs:label "cone retinal bipolar cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of neuromuscular junction development) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:7722643") "Any process that modulates the frequency, rate or extent of neuromuscular junction development.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-06-23T19:23:42Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of neuromuscular junction organization") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of NMJ stability") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of neuromuscular junction stability") -AnnotationAssertion( "GO:1904396") -AnnotationAssertion(rdfs:label "regulation of neuromuscular junction development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of neuromuscular junction development) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:7722643") "Any process that stops, prevents or reduces the frequency, rate or extent of neuromuscular junction development.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-06-23T19:23:48Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of neuromuscular junction development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of neuromuscular junction organization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of neuromuscular junction development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of neuromuscular junction organization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of neuromuscular junction development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of neuromuscular junction organization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of neuromuscular junction organization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of neuromuscular junction development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of neuromuscular junction organization") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of NMJ stability") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of neuromuscular junction stability") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of NMJ stability") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of neuromuscular junction stability") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of NMJ stability") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of neuromuscular junction stability") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of NMJ stability") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of neuromuscular junction stability") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of NMJ stability") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of neuromuscular junction stability") -AnnotationAssertion( "GO:1904397") -AnnotationAssertion(rdfs:label "negative regulation of neuromuscular junction development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of neuromuscular junction development) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:7722643") "Any process that activates or increases the frequency, rate or extent of neuromuscular junction development.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-06-23T19:23:54Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of neuromuscular junction organization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of neuromuscular junction development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of neuromuscular junction organization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of neuromuscular junction development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of neuromuscular junction organization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of neuromuscular junction development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of neuromuscular junction organization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of neuromuscular junction development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of neuromuscular junction organization") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of NMJ stability") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of neuromuscular junction stability") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of NMJ stability") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of neuromuscular junction stability") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of NMJ stability") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of neuromuscular junction stability") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of NMJ stability") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of neuromuscular junction stability") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of NMJ stability") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of neuromuscular junction stability") -AnnotationAssertion( "GO:1904398") -AnnotationAssertion(rdfs:label "positive regulation of neuromuscular junction development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (melatonin binding) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mr") Annotation( "GO_REF:0000067") Annotation( "PMID:10379923") "Binding to melatonin.") -AnnotationAssertion( "mr") -AnnotationAssertion( "2015-06-25T19:19:53Z") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:1904408") -AnnotationAssertion(rdfs:label "melatonin binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of secretory granule organization) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:15039777") "Any process that modulates the frequency, rate or extent of secretory granule organization.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-06-25T19:40:42Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of secretory granule organisation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of secretory granule organization and biogenesis") -AnnotationAssertion( "GO:1904409") -AnnotationAssertion(rdfs:label "regulation of secretory granule organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of secretory granule organization) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:15039777") "Any process that stops, prevents or reduces the frequency, rate or extent of secretory granule organization.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-06-25T19:40:49Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of secretory granule organisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of secretory granule organization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of secretory granule organisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of secretory granule organization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of secretory granule organisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of secretory granule organization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of secretory granule organisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of secretory granule organisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of secretory granule organization") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of secretory granule organization and biogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of secretory granule organization and biogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of secretory granule organization and biogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of secretory granule organization and biogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of secretory granule organization and biogenesis") -AnnotationAssertion( "GO:1904410") -AnnotationAssertion(rdfs:label "negative regulation of secretory granule organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of secretory granule organization) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:15039777") "Any process that activates or increases the frequency, rate or extent of secretory granule organization.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-06-25T19:40:55Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of secretory granule organisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of secretory granule organisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of secretory granule organization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of secretory granule organisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of secretory granule organization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of secretory granule organisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of secretory granule organization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of secretory granule organisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of secretory granule organization") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of secretory granule organization and biogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of secretory granule organization and biogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of secretory granule organization and biogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of secretory granule organization and biogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of secretory granule organization and biogenesis") -AnnotationAssertion( "GO:1904411") -AnnotationAssertion(rdfs:label "positive regulation of secretory granule organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of cardiac ventricle development) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:19590510") "Any process that modulates the frequency, rate or extent of cardiac ventricle development.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-06-25T19:52:15Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904412") -AnnotationAssertion(rdfs:label "regulation of cardiac ventricle development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of cardiac ventricle development) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:19590510") "Any process that stops, prevents or reduces the frequency, rate or extent of cardiac ventricle development.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-06-25T19:52:21Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of cardiac ventricle development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of cardiac ventricle development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of cardiac ventricle development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of cardiac ventricle development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904413") -AnnotationAssertion(rdfs:label "negative regulation of cardiac ventricle development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of cardiac ventricle development) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:19590510") "Any process that activates or increases the frequency, rate or extent of cardiac ventricle development.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-06-25T19:52:27Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of cardiac ventricle development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of cardiac ventricle development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of cardiac ventricle development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of cardiac ventricle development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904414") -AnnotationAssertion(rdfs:label "positive regulation of cardiac ventricle development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of calcium ion transmembrane transport) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:22910094") "Any process that activates or increases the frequency, rate or extent of calcium ion transmembrane transport.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-07-02T20:44:25Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of calcium ion membrane transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of transmembrane calcium transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of calcium ion membrane transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of calcium ion transmembrane transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of transmembrane calcium transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of calcium ion membrane transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of calcium ion transmembrane transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of transmembrane calcium transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of calcium ion membrane transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of calcium ion transmembrane transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of transmembrane calcium transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of calcium ion membrane transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of calcium ion transmembrane transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of transmembrane calcium transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904427") -AnnotationAssertion(rdfs:label "positive regulation of calcium ion transmembrane transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of iron ion import across plasma membrane) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:kom") Annotation( "GO_REF:0000058") Annotation( "PMID:18353247") "Any process that modulates the frequency, rate or extent of iron ions import across plasma membrane.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2015-03-04T14:37:36Z") -AnnotationAssertion( "GO:1903989") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of ferrous ion import into cell") -AnnotationAssertion( "regulation of ferrous iron import across plasma membrane") -AnnotationAssertion( "regulation of ferrous iron import into cell") -AnnotationAssertion( "GO:1904438") -AnnotationAssertion(rdfs:label "regulation of iron ion import across plasma membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (negative regulation of iron ion import across plasma membrane) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:kom") Annotation( "GO_REF:0000058") Annotation( "PMID:18353247") "Any process that stops, prevents or reduces the frequency, rate or extent of iron ions import across plasma membrane.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2015-07-06T13:49:58Z") -AnnotationAssertion( "GO:1903990") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of ferrous ion import into cell") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of ferrous iron import across plasma membrane") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of ferrous ion import into cell") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of ferrous iron import across plasma membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of ferrous ion import into cell") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of ferrous iron import across plasma membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of ferrous ion import into cell") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of ferrous iron import across plasma membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of ferrous ion import into cell") -AnnotationAssertion( "negative regulation of ferrous iron import across plasma membrane") -AnnotationAssertion( "negative regulation of ferrous iron import into cell") -AnnotationAssertion( "GO:1904439") -AnnotationAssertion(rdfs:label "negative regulation of iron ion import across plasma membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of iron ion import across plasma membrane) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:kom") Annotation( "GO_REF:0000058") Annotation( "PMID:18353247") "Any process that activates or increases the frequency, rate or extent of iron ions import across plasma membrane.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2015-07-06T13:50:04Z") -AnnotationAssertion( "GO:1903991") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of ferrous ion import into cell") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of ferrous iron import across plasma membrane") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of ferrous ion import into cell") -AnnotationAssertion( "positive regulation of ferrous iron import across plasma membrane") -AnnotationAssertion( "positive regulation of ferrous iron import into cell") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of ferrous ion import into cell") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of ferrous iron import across plasma membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of ferrous ion import into cell") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of ferrous iron import across plasma membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of ferrous ion import into cell") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of ferrous iron import across plasma membrane") -AnnotationAssertion( "GO:1904440") -AnnotationAssertion(rdfs:label "positive regulation of iron ion import across plasma membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of neuronal action potential) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:25126967") "Any process that stops, prevents or reduces the frequency, rate or extent of neuronal action potential.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-07-09T18:02:40Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of neuronal action potential") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of neuronal action potential") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of neuronal action potential") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of neuronal action potential") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of generation of action potential") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of generation of action potential") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of generation of action potential") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of generation of action potential") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of generation of action potential") -AnnotationAssertion( "GO:1904456") -AnnotationAssertion(rdfs:label "negative regulation of neuronal action potential") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of neuronal action potential) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:25126967") "Any process that activates or increases the frequency, rate or extent of neuronal action potential.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-07-09T18:02:46Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of neuronal action potential") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of neuronal action potential") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of neuronal action potential") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of neuronal action potential") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of generation of action potential") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of generation of action potential") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of generation of action potential") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of generation of action potential") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of generation of action potential") -AnnotationAssertion( "GO:1904457") -AnnotationAssertion(rdfs:label "positive regulation of neuronal action potential") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (cloacal gland development) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mr") Annotation( "GO_REF:0000094") Annotation( "PMID:18805421") "The process whose specific outcome is the progression of a cloacal gland over time, from its formation to the mature structure.") -AnnotationAssertion( "mr") -AnnotationAssertion( "2015-07-15T22:14:39Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904484") -AnnotationAssertion(rdfs:label "cloacal gland development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (protein localization to ciliary transition zone) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:kmv") Annotation( "GO_REF:0000087") Annotation( "PMID:21422230") "A process in which a protein is transported to, or maintained in, a location within a ciliary transition zone.") -AnnotationAssertion( "kmv") -AnnotationAssertion( "2015-07-17T20:43:21Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "protein localisation in ciliary transition zone") -AnnotationAssertion(Annotation( "GOC:TermGenie") "protein localisation to ciliary transition zone") -AnnotationAssertion(Annotation( "GOC:TermGenie") "protein localization in ciliary transition zone") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904491") -AnnotationAssertion(rdfs:label "protein localization to ciliary transition zone") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of microtubule binding) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:als") Annotation( "GO_REF:0000059") Annotation( "PMID:24520051") "Any process that modulates the frequency, rate or extent of microtubule binding.") -AnnotationAssertion( "als") -AnnotationAssertion( "2015-07-30T10:32:13Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of microtubule severing activity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of microtubule/chromatin interaction") -AnnotationAssertion( "GO:1904526") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "regulation of microtubule binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of microtubule binding) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:als") Annotation( "GO_REF:0000059") Annotation( "PMID:24520051") "Any process that stops, prevents or reduces the frequency, rate or extent of microtubule binding.") -AnnotationAssertion( "als") -AnnotationAssertion( "2015-07-30T10:32:29Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of microtubule binding") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of microtubule binding") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of microtubule binding") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of microtubule binding") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of microtubule severing activity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of microtubule/chromatin interaction") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of microtubule severing activity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of microtubule/chromatin interaction") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of microtubule severing activity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of microtubule/chromatin interaction") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of microtubule severing activity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of microtubule/chromatin interaction") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of microtubule severing activity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of microtubule/chromatin interaction") -AnnotationAssertion( "GO:1904527") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "negative regulation of microtubule binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of microtubule binding) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:als") Annotation( "GO_REF:0000059") Annotation( "PMID:24520051") "Any process that activates or increases the frequency, rate or extent of microtubule binding.") -AnnotationAssertion( "als") -AnnotationAssertion( "2015-07-30T10:32:36Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of microtubule binding") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of microtubule binding") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of microtubule binding") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of microtubule binding") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of microtubule severing activity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of microtubule/chromatin interaction") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of microtubule severing activity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of microtubule/chromatin interaction") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of microtubule severing activity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of microtubule/chromatin interaction") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of microtubule severing activity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of microtubule/chromatin interaction") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of microtubule severing activity") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of microtubule/chromatin interaction") -AnnotationAssertion( "GO:1904528") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "positive regulation of microtubule binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (response to glycoprotein) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000071") Annotation( "PMID:14597422") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycoprotein stimulus.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-08-20T16:46:24Z") -AnnotationAssertion( "response to glycoproteins") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904587") -AnnotationAssertion(rdfs:label "response to glycoprotein") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cellular response to glycoprotein) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000071") Annotation( "PMID:14597422") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycoprotein stimulus.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-08-20T16:46:30Z") -AnnotationAssertion( "cellular response to glycoproteins") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904588") -AnnotationAssertion(rdfs:label "cellular response to glycoprotein") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (fat cell apoptotic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000085") Annotation( "PMID:17024416") "Any apoptotic process in a fat cell.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-08-27T18:13:06Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "adipocyte apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "adipose cell apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "adipocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "adipose cell apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "fat cell apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904606") -AnnotationAssertion(rdfs:label "fat cell apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of podocyte apoptotic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:23692924") "Any process that modulates the frequency, rate or extent of glomerular visceral epithelial cell apoptotic process.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/23000"^^xsd:anyURI) -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-08-28T14:14:44Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of glomerular podocyte apoptotic process") -AnnotationAssertion( "regulation of glomerular visceral epithelial cell apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of glomerular podocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of glomerular visceral epithelial cell apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of podocyte apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904633") -AnnotationAssertion(rdfs:label "regulation of podocyte apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of podocyte apoptotic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:23692924") "Any process that stops, prevents or reduces the frequency, rate or extent of glomerular visceral epithelial cell apoptotic process.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/23000"^^xsd:anyURI) -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-08-28T14:14:50Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of glomerular podocyte apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of glomerular visceral epithelial cell apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of podocyte apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of glomerular podocyte apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of glomerular visceral epithelial cell apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of podocyte apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of glomerular podocyte apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of glomerular visceral epithelial cell apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of podocyte apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of glomerular podocyte apoptotic process") -AnnotationAssertion( "negative regulation of glomerular visceral epithelial cell apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of podocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of glomerular podocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of glomerular visceral epithelial cell apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of podocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of glomerular podocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of glomerular visceral epithelial cell apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of podocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of glomerular podocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of glomerular visceral epithelial cell apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of podocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of glomerular podocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of glomerular podocyte apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of glomerular visceral epithelial cell apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of glomerular visceral epithelial cell apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of podocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of podocyte apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of glomerular podocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of glomerular visceral epithelial cell apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904634") -AnnotationAssertion(rdfs:label "negative regulation of podocyte apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of podocyte apoptotic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:23692924") "Any process that activates or increases the frequency, rate or extent of glomerular visceral epithelial cell apoptotic process.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/23000"^^xsd:anyURI) -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-08-28T14:14:56Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of glomerular podocyte apoptotic process") -AnnotationAssertion( "positive regulation of glomerular visceral epithelial cell apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of glomerular podocyte apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of glomerular visceral epithelial cell apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of podocyte apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of glomerular podocyte apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of glomerular visceral epithelial cell apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of podocyte apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of glomerular podocyte apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of glomerular visceral epithelial cell apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of podocyte apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of glomerular podocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of glomerular podocyte apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of glomerular visceral epithelial cell apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of glomerular visceral epithelial cell apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of podocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of podocyte apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of glomerular podocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of glomerular visceral epithelial cell apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of podocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of glomerular podocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of glomerular visceral epithelial cell apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of podocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of glomerular podocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of glomerular visceral epithelial cell apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of podocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of glomerular podocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of glomerular visceral epithelial cell apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of podocyte apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904635") -AnnotationAssertion(rdfs:label "positive regulation of podocyte apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of fat cell apoptotic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:17024416") "Any process that modulates the frequency, rate or extent of fat cell apoptotic process.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-08-31T20:59:28Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of adipocyte apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of adipose cell apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of adipocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of adipose cell apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of fat cell apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904649") -AnnotationAssertion(rdfs:label "regulation of fat cell apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of fat cell apoptotic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:17024416") "Any process that stops, prevents or reduces the frequency, rate or extent of fat cell apoptotic process.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-08-31T20:59:34Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of adipocyte apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of adipose cell apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of fat cell apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of adipocyte apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of adipose cell apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of fat cell apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of adipocyte apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of adipose cell apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of fat cell apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of adipocyte apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of adipose cell apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of adipocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of adipose cell apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of fat cell apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of adipocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of adipose cell apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of fat cell apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of adipocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of adipose cell apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of fat cell apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of adipocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of adipocyte apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of adipose cell apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of adipose cell apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of fat cell apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of fat cell apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of adipocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of adipose cell apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of fat cell apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904650") -AnnotationAssertion(rdfs:label "negative regulation of fat cell apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of fat cell apoptotic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:17024416") "Any process that activates or increases the frequency, rate or extent of fat cell apoptotic process.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-08-31T20:59:40Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of adipocyte apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of adipose cell apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of adipocyte apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of adipose cell apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of fat cell apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of adipocyte apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of adipose cell apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of fat cell apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of adipocyte apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of adipose cell apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of fat cell apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of adipocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of adipocyte apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of adipose cell apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of adipose cell apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of fat cell apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of fat cell apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of adipocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of adipose cell apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of fat cell apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of adipocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of adipose cell apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of fat cell apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of adipocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of adipose cell apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of fat cell apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of adipocyte apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of adipose cell apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of fat cell apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904651") -AnnotationAssertion(rdfs:label "positive regulation of fat cell apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of lung alveolus development) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:23962064") "Any process that modulates the frequency, rate or extent of lung alveolus development.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-09-03T22:44:44Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of alveolarization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of alveologenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904653") -AnnotationAssertion(rdfs:label "regulation of lung alveolus development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of lung alveolus development) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:23962064") "Any process that stops, prevents or reduces the frequency, rate or extent of lung alveolus development.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-09-03T22:44:50Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of alveolarization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of alveologenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of lung alveolus development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of alveolarization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of alveologenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of lung alveolus development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of alveolarization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of alveologenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of lung alveolus development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of alveolarization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of alveologenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of alveolarization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of alveologenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of lung alveolus development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904654") -AnnotationAssertion(rdfs:label "negative regulation of lung alveolus development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of lung alveolus development) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:23962064") "Any process that activates or increases the frequency, rate or extent of lung alveolus development.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-09-03T22:44:56Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of alveolarization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of alveologenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of alveolarization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of alveologenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of lung alveolus development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of alveolarization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of alveologenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of lung alveolus development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of alveolarization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of alveologenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of lung alveolus development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of alveolarization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of alveologenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of lung alveolus development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904655") -AnnotationAssertion(rdfs:label "positive regulation of lung alveolus development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (glucose transmembrane transport) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000069") Annotation( "PMID:9090050") "The process in which glucose is transported across a membrane.") -AnnotationAssertion( "vw") -AnnotationAssertion( "2015-09-04T17:20:16Z") -AnnotationAssertion( "GO:0015758") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "glucose transport") -AnnotationAssertion( "GO:1904659") -AnnotationAssertion(rdfs:label "glucose transmembrane transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of cell differentiation involved in stem cell population maintenance) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_miRNA") Annotation( "GOC:TermGenie") Annotation( "GOC:rph") Annotation( "GO_REF:0000060") Annotation( "PMID:19409607") "Any negative regulation of cell differentiation that is involved in stem cell population maintenance.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2015-09-12T00:46:08Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of cell differentiation involved in stem cell population maintenance") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of cell differentiation involved in stem cell population maintenance") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of cell differentiation involved in stem cell population maintenance") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of cell differentiation involved in stem cell population maintenance") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of cell differentiation involved in maintenance of pluripotency") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of cell differentiation involved in maintenance of pluripotency") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of cell differentiation involved in maintenance of pluripotency") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of cell differentiation involved in maintenance of pluripotency") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of cell differentiation involved in maintenance of pluripotency") -AnnotationAssertion( "GO:1904671") -AnnotationAssertion(rdfs:label "negative regulation of cell differentiation involved in stem cell population maintenance") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of somatic stem cell population maintenance) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_miRNA") Annotation( "GOC:TermGenie") Annotation( "GOC:rph") Annotation( "GO_REF:0000058") Annotation( "PMID:19409607") "Any process that modulates the frequency, rate or extent of somatic stem cell population maintenance.") -AnnotationAssertion( "rph") -AnnotationAssertion( "2015-09-14T08:40:19Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904672") -AnnotationAssertion(rdfs:label "regulation of somatic stem cell population maintenance") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of somatic stem cell population maintenance) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_miRNA") Annotation( "GOC:TermGenie") Annotation( "GOC:rph") Annotation( "GO_REF:0000058") Annotation( "PMID:19409607") "Any process that stops, prevents or reduces the frequency, rate or extent of somatic stem cell population maintenance.") -AnnotationAssertion( "rph") -AnnotationAssertion( "2015-09-14T08:40:25Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of somatic stem cell population maintenance") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of somatic stem cell population maintenance") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of somatic stem cell population maintenance") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of somatic stem cell population maintenance") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904673") -AnnotationAssertion(rdfs:label "negative regulation of somatic stem cell population maintenance") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of somatic stem cell population maintenance) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_miRNA") Annotation( "GOC:TermGenie") Annotation( "GOC:rph") Annotation( "GO_REF:0000058") Annotation( "PMID:19409607") "Any process that activates or increases the frequency, rate or extent of somatic stem cell population maintenance.") -AnnotationAssertion( "rph") -AnnotationAssertion( "2015-09-14T08:40:32Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of somatic stem cell population maintenance") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of somatic stem cell population maintenance") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of somatic stem cell population maintenance") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of somatic stem cell population maintenance") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904674") -AnnotationAssertion(rdfs:label "positive regulation of somatic stem cell population maintenance") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of somatic stem cell division) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_miRNA") Annotation( "GOC:TermGenie") Annotation( "GOC:rph") Annotation( "GO_REF:0000058") Annotation( "PMID:19409607") "Any process that modulates the frequency, rate or extent of somatic stem cell division.") -AnnotationAssertion( "rph") -AnnotationAssertion( "2015-09-14T08:47:22Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of somatic stem cell renewal") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904675") -AnnotationAssertion(rdfs:label "regulation of somatic stem cell division") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of somatic stem cell division) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_miRNA") Annotation( "GOC:TermGenie") Annotation( "GOC:rph") Annotation( "GO_REF:0000058") Annotation( "PMID:19409607") "Any process that stops, prevents or reduces the frequency, rate or extent of somatic stem cell division.") -AnnotationAssertion( "rph") -AnnotationAssertion( "2015-09-14T08:47:28Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of somatic stem cell division") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of somatic stem cell renewal") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of somatic stem cell division") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of somatic stem cell renewal") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of somatic stem cell division") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of somatic stem cell renewal") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of somatic stem cell renewal") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of somatic stem cell division") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of somatic stem cell renewal") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904676") -AnnotationAssertion(rdfs:label "negative regulation of somatic stem cell division") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of somatic stem cell division) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_miRNA") Annotation( "GOC:TermGenie") Annotation( "GOC:rph") Annotation( "GO_REF:0000058") Annotation( "PMID:19409607") "Any process that activates or increases the frequency, rate or extent of somatic stem cell division.") -AnnotationAssertion( "rph") -AnnotationAssertion( "2015-09-14T08:47:34Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of somatic stem cell renewal") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of somatic stem cell division") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of somatic stem cell renewal") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of somatic stem cell division") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of somatic stem cell renewal") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of somatic stem cell division") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of somatic stem cell renewal") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of somatic stem cell division") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of somatic stem cell renewal") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904677") -AnnotationAssertion(rdfs:label "positive regulation of somatic stem cell division") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (peptide transmembrane transporter activity) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:vw") Annotation( "GO_REF:0000070") "Enables the transfer of a peptide from one side of a membrane to the other.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2015-09-22T18:50:41Z") -AnnotationAssertion( "GO:0015197") -AnnotationAssertion( "GO:0015637") -AnnotationAssertion(Annotation(rdfs:label "Glutathione is taken up by the bacterium") "Reactome:R-HSA-1500817") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "peptide transporter activity") -AnnotationAssertion( "peptide uptake permease activity") -AnnotationAssertion( "GO:1904680") -AnnotationAssertion(rdfs:label "peptide transmembrane transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (regulation of cytoplasmic translational initiation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:12242291") "Any process that modulates the frequency, rate or extent of cytoplasmic translational initiation.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/21560"^^xsd:anyURI) -AnnotationAssertion( "dos") -AnnotationAssertion( "2015-09-25T14:39:38Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904688") -AnnotationAssertion(rdfs:label "regulation of cytoplasmic translational initiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (negative regulation of cytoplasmic translational initiation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:12242291") "Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic translational initiation.") -AnnotationAssertion( "dos") -AnnotationAssertion( "2015-09-25T14:39:44Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of cytoplasmic translational initiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of cytoplasmic translational initiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of cytoplasmic translational initiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of cytoplasmic translational initiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904689") -AnnotationAssertion(rdfs:label "negative regulation of cytoplasmic translational initiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of cytoplasmic translational initiation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:12242291") "Any process that activates or increases the frequency, rate or extent of cytoplasmic translational initiation.") -AnnotationAssertion( "dos") -AnnotationAssertion( "2015-09-25T14:39:50Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of cytoplasmic translational initiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of cytoplasmic translational initiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of cytoplasmic translational initiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of cytoplasmic translational initiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904690") -AnnotationAssertion(rdfs:label "positive regulation of cytoplasmic translational initiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of type B pancreatic cell proliferation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:24055447") "Any process that stops, prevents or reduces the frequency, rate or extent of type B pancreatic cell proliferation.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-09-25T15:23:38Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of pancreatic B cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of pancreatic beta cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of type B pancreatic cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of pancreatic B cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of pancreatic beta cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of type B pancreatic cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of pancreatic B cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of pancreatic beta cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of type B pancreatic cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of pancreatic B cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of pancreatic beta cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of pancreatic B cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of pancreatic beta cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of type B pancreatic cell proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904691") -AnnotationAssertion(rdfs:label "negative regulation of type B pancreatic cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of type B pancreatic cell proliferation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:24055447") "Any process that activates or increases the frequency, rate or extent of type B pancreatic cell proliferation.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-09-25T15:23:44Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of pancreatic B cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of pancreatic beta cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of pancreatic B cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of pancreatic beta cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of type B pancreatic cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of pancreatic B cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of pancreatic beta cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of type B pancreatic cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of pancreatic B cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of pancreatic beta cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of type B pancreatic cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of pancreatic B cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of pancreatic beta cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of type B pancreatic cell proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904692") -AnnotationAssertion(rdfs:label "positive regulation of type B pancreatic cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (midbrain morphogenesis) - -AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:TermGenie") Annotation( "GOC:bf") Annotation( "GO_REF:0000083") Annotation( "PMID:21347250") "The developmental process by which a midbrain is generated and organized.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2015-09-29T09:15:28Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "MB morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "mesencephalon morphogenesis") -AnnotationAssertion( "GO:1904693") -AnnotationAssertion(rdfs:label "midbrain morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (regulation of acinar cell proliferation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:9788538") "Any process that modulates the frequency, rate or extent of acinar cell proliferation.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-09-30T15:19:50Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of acinic cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of acinous cell proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904697") -AnnotationAssertion(rdfs:label "regulation of acinar cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of acinar cell proliferation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:9788538") "Any process that stops, prevents or reduces the frequency, rate or extent of acinar cell proliferation.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-09-30T15:19:57Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of acinar cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of acinic cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of acinous cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of acinar cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of acinic cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of acinous cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of acinar cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of acinic cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of acinous cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of acinic cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of acinous cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of acinar cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of acinic cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of acinous cell proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904698") -AnnotationAssertion(rdfs:label "negative regulation of acinar cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of acinar cell proliferation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:9788538") "Any process that activates or increases the frequency, rate or extent of acinar cell proliferation.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-09-30T15:20:03Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of acinic cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of acinous cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of acinar cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of acinic cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of acinous cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of acinar cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of acinic cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of acinous cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of acinar cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of acinic cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of acinous cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of acinar cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of acinic cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of acinous cell proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904699") -AnnotationAssertion(rdfs:label "positive regulation of acinar cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (granulosa cell apoptotic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000085") Annotation( "PMID:19208546") "Any apoptotic process in a granulosa cell.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-09-30T21:29:54Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "granulosa cell of ovary apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "granulosa cell apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "granulosa cell of ovary apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904700") -AnnotationAssertion(rdfs:label "granulosa cell apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of vascular associated smooth muscle cell proliferation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:23246467") "Any process that modulates the frequency, rate or extent of vascular smooth muscle cell proliferation.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-10-01T16:05:20Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of VSMC proliferation") -AnnotationAssertion( "regulation of vascular smooth muscle cell proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904705") -AnnotationAssertion(rdfs:label "regulation of vascular associated smooth muscle cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of vascular associated smooth muscle cell proliferation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:23246467") "Any process that stops, prevents or reduces the frequency, rate or extent of vascular smooth muscle cell proliferation.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-10-01T16:05:26Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of VSMC proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of vascular smooth muscle cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of VSMC proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of vascular smooth muscle cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of VSMC proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of vascular smooth muscle cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of VSMC proliferation") -AnnotationAssertion( "negative regulation of vascular smooth muscle cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of VSMC proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of vascular smooth muscle cell proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904706") -AnnotationAssertion(rdfs:label "negative regulation of vascular associated smooth muscle cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of vascular associated smooth muscle cell proliferation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:23246467") "Any process that activates or increases the frequency, rate or extent of vascular smooth muscle cell proliferation.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-10-01T16:05:32Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of VSMC proliferation") -AnnotationAssertion( "positive regulation of vascular smooth muscle cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of VSMC proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of vascular smooth muscle cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of VSMC proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of vascular smooth muscle cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of VSMC proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of vascular smooth muscle cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of VSMC proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of vascular smooth muscle cell proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904707") -AnnotationAssertion(rdfs:label "positive regulation of vascular associated smooth muscle cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of granulosa cell apoptotic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:19208546") "Any process that modulates the frequency, rate or extent of granulosa cell apoptotic process.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-10-01T16:09:38Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of granulosa cell of ovary apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of granulosa cell apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of granulosa cell of ovary apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904708") -AnnotationAssertion(rdfs:label "regulation of granulosa cell apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of granulosa cell apoptotic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:19208546") "Any process that stops, prevents or reduces the frequency, rate or extent of granulosa cell apoptotic process.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-10-01T16:09:45Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of granulosa cell apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of granulosa cell of ovary apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of granulosa cell apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of granulosa cell of ovary apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of granulosa cell apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of granulosa cell of ovary apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of granulosa cell of ovary apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of granulosa cell apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of granulosa cell of ovary apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of granulosa cell apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of granulosa cell of ovary apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of granulosa cell apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of granulosa cell of ovary apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of granulosa cell apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of granulosa cell apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of granulosa cell of ovary apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of granulosa cell of ovary apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of granulosa cell apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of granulosa cell of ovary apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904709") -AnnotationAssertion(rdfs:label "negative regulation of granulosa cell apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of granulosa cell apoptotic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:19208546") "Any process that activates or increases the frequency, rate or extent of granulosa cell apoptotic process.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-10-01T16:09:51Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of granulosa cell of ovary apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of granulosa cell apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of granulosa cell of ovary apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of granulosa cell apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of granulosa cell of ovary apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of granulosa cell apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of granulosa cell of ovary apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of granulosa cell apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of granulosa cell apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of granulosa cell of ovary apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of granulosa cell of ovary apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of granulosa cell apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of granulosa cell of ovary apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of granulosa cell apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of granulosa cell of ovary apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of granulosa cell apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of granulosa cell of ovary apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of granulosa cell apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of granulosa cell of ovary apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904710") -AnnotationAssertion(rdfs:label "positive regulation of granulosa cell apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (vascular associated smooth muscle cell migration) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_miRNA") Annotation( "GOC:TermGenie") Annotation( "GOC:rph") Annotation( "GO_REF:0000091") Annotation( "PMID:20693317") "The orderly movement of a vascular associated smooth muscle cell from one site to another.") -AnnotationAssertion( "rph") -AnnotationAssertion( "2015-10-15T09:56:00Z") -AnnotationAssertion( "vascular smooth muscle cell migration") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904738") -AnnotationAssertion(rdfs:label "vascular associated smooth muscle cell migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of apoptotic process involved in development) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:22801495") "Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in development.") -AnnotationAssertion( "es") -AnnotationAssertion( "2015-10-19T14:12:27Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of apoptotic cell death involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of apoptotic cell death involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of apoptotic process involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of apoptotic process involved in development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of apoptotic process involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of apoptotic programmed cell death involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of apoptotic programmed cell death involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of programmed cell death by apoptosis involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of programmed cell death by apoptosis involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of apoptotic cell death involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of apoptotic cell death involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of apoptotic process involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of apoptotic process involved in development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of apoptotic process involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of apoptotic programmed cell death involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of apoptotic programmed cell death involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of programmed cell death by apoptosis involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of programmed cell death by apoptosis involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of apoptotic cell death involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of apoptotic cell death involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of apoptotic process involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of apoptotic process involved in development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of apoptotic process involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of apoptotic programmed cell death involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of apoptotic programmed cell death involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of programmed cell death by apoptosis involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of programmed cell death by apoptosis involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of apoptotic cell death involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of apoptotic cell death involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of apoptotic process involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of apoptotic process involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of apoptotic programmed cell death involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of apoptotic programmed cell death involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of programmed cell death by apoptosis involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of programmed cell death by apoptosis involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of activation of apoptosis involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of activation of apoptosis involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of apoptosis involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of apoptosis involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of apoptosis signaling involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of apoptosis signaling involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of apoptotic program involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of apoptotic program involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of type I programmed cell death involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of type I programmed cell death involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of activation of apoptosis involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of activation of apoptosis involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of apoptosis involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of apoptosis involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of apoptosis signaling involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of apoptosis signaling involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of apoptotic program involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of apoptotic program involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of type I programmed cell death involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of type I programmed cell death involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of activation of apoptosis involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of activation of apoptosis involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of apoptosis involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of apoptosis involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of apoptosis signaling involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of apoptosis signaling involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of apoptotic program involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of apoptotic program involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of type I programmed cell death involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of type I programmed cell death involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of activation of apoptosis involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of activation of apoptosis involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of apoptosis involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of apoptosis involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of apoptosis signaling involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of apoptosis signaling involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of apoptotic cell death involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of apoptotic cell death involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of apoptotic process involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of apoptotic process involved in development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of apoptotic process involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of apoptotic program involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of apoptotic program involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of apoptotic programmed cell death involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of apoptotic programmed cell death involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of programmed cell death by apoptosis involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of programmed cell death by apoptosis involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of type I programmed cell death involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of type I programmed cell death involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of activation of apoptosis involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of activation of apoptosis involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of apoptosis involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of apoptosis involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of apoptosis signaling involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of apoptosis signaling involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of apoptotic program involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of apoptotic program involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of type I programmed cell death involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of type I programmed cell death involved in development of an anatomical structure") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of apoptosis activator activity involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of apoptosis activator activity involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of commitment to apoptosis involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of commitment to apoptosis involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of induction of apoptosis by p53 involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of induction of apoptosis by p53 involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of induction of apoptosis involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of induction of apoptosis involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of signaling (initiator) caspase activity involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of signaling (initiator) caspase activity involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of apoptosis activator activity involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of apoptosis activator activity involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of commitment to apoptosis involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of commitment to apoptosis involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of induction of apoptosis by p53 involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of induction of apoptosis by p53 involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of induction of apoptosis involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of induction of apoptosis involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of signaling (initiator) caspase activity involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of signaling (initiator) caspase activity involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of apoptosis activator activity involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of apoptosis activator activity involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of commitment to apoptosis involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of commitment to apoptosis involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of induction of apoptosis by p53 involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of induction of apoptosis by p53 involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of induction of apoptosis involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of induction of apoptosis involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of signaling (initiator) caspase activity involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of signaling (initiator) caspase activity involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of apoptosis activator activity involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of apoptosis activator activity involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of commitment to apoptosis involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of commitment to apoptosis involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of induction of apoptosis by p53 involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of induction of apoptosis by p53 involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of induction of apoptosis involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of induction of apoptosis involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of signaling (initiator) caspase activity involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of signaling (initiator) caspase activity involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of apoptosis activator activity involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of apoptosis activator activity involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of commitment to apoptosis involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of commitment to apoptosis involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of induction of apoptosis by p53 involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of induction of apoptosis by p53 involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of induction of apoptosis involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of induction of apoptosis involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of signaling (initiator) caspase activity involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of signaling (initiator) caspase activity involved in development of an anatomical structure") -AnnotationAssertion( "GO:1904746") -AnnotationAssertion(rdfs:comment "U4PR86 in PMID:22801495 inferred from mutant phenotype") -AnnotationAssertion(rdfs:label "negative regulation of apoptotic process involved in development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of apoptotic process involved in development) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:22801495") "Any process that activates or increases the frequency, rate or extent of apoptotic process involved in development.") -AnnotationAssertion( "es") -AnnotationAssertion( "2015-10-19T14:12:34Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of apoptotic cell death involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of apoptotic cell death involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of apoptotic process involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of apoptotic process involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of apoptotic programmed cell death involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of apoptotic programmed cell death involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of programmed cell death by apoptosis involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of programmed cell death by apoptosis involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of apoptotic cell death involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of apoptotic cell death involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of apoptotic process involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of apoptotic process involved in development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of apoptotic process involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of apoptotic programmed cell death involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of apoptotic programmed cell death involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of programmed cell death by apoptosis involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of programmed cell death by apoptosis involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of apoptotic cell death involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of apoptotic cell death involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of apoptotic process involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of apoptotic process involved in development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of apoptotic process involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of apoptotic programmed cell death involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of apoptotic programmed cell death involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of programmed cell death by apoptosis involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of programmed cell death by apoptosis involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of apoptotic cell death involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of apoptotic cell death involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of apoptotic process involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of apoptotic process involved in development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of apoptotic process involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of apoptotic programmed cell death involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of apoptotic programmed cell death involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of programmed cell death by apoptosis involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of programmed cell death by apoptosis involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of activation of apoptosis involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of activation of apoptosis involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of apoptosis involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of apoptosis involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of apoptosis signaling involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of apoptosis signaling involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of apoptotic cell death involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of apoptotic cell death involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of apoptotic process involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of apoptotic process involved in development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of apoptotic process involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of apoptotic program involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of apoptotic program involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of apoptotic programmed cell death involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of apoptotic programmed cell death involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of programmed cell death by apoptosis involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of programmed cell death by apoptosis involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of type I programmed cell death involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of type I programmed cell death involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of activation of apoptosis involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of activation of apoptosis involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of apoptosis involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of apoptosis involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of apoptosis signaling involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of apoptosis signaling involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of apoptotic program involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of apoptotic program involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of type I programmed cell death involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of type I programmed cell death involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of activation of apoptosis involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of activation of apoptosis involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of apoptosis involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of apoptosis involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of apoptosis signaling involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of apoptosis signaling involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of apoptotic program involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of apoptotic program involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of type I programmed cell death involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of type I programmed cell death involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of activation of apoptosis involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of activation of apoptosis involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of apoptosis involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of apoptosis involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of apoptosis signaling involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of apoptosis signaling involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of apoptotic program involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of apoptotic program involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of type I programmed cell death involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of type I programmed cell death involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of activation of apoptosis involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of activation of apoptosis involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of apoptosis involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of apoptosis involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of apoptosis signaling involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of apoptosis signaling involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of apoptotic program involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of apoptotic program involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of type I programmed cell death involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of type I programmed cell death involved in development of an anatomical structure") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of apoptosis activator activity involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of apoptosis activator activity involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of commitment to apoptosis involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of commitment to apoptosis involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of induction of apoptosis by p53 involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of induction of apoptosis by p53 involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of induction of apoptosis involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of induction of apoptosis involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of signaling (initiator) caspase activity involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of signaling (initiator) caspase activity involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of apoptosis activator activity involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of apoptosis activator activity involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of commitment to apoptosis involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of commitment to apoptosis involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of induction of apoptosis by p53 involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of induction of apoptosis by p53 involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of induction of apoptosis involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of induction of apoptosis involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of signaling (initiator) caspase activity involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of signaling (initiator) caspase activity involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of apoptosis activator activity involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of apoptosis activator activity involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of commitment to apoptosis involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of commitment to apoptosis involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of induction of apoptosis by p53 involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of induction of apoptosis by p53 involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of induction of apoptosis involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of induction of apoptosis involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of signaling (initiator) caspase activity involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of signaling (initiator) caspase activity involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of apoptosis activator activity involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of apoptosis activator activity involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of commitment to apoptosis involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of commitment to apoptosis involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of induction of apoptosis by p53 involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of induction of apoptosis by p53 involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of induction of apoptosis involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of induction of apoptosis involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of signaling (initiator) caspase activity involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of signaling (initiator) caspase activity involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of apoptosis activator activity involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of apoptosis activator activity involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of commitment to apoptosis involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of commitment to apoptosis involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of induction of apoptosis by p53 involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of induction of apoptosis by p53 involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of induction of apoptosis involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of induction of apoptosis involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of signaling (initiator) caspase activity involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of signaling (initiator) caspase activity involved in development of an anatomical structure") -AnnotationAssertion( "GO:1904747") -AnnotationAssertion(rdfs:comment "U4PR86 in PMID:22801495 inferred from mutant phenotype") -AnnotationAssertion(rdfs:label "positive regulation of apoptotic process involved in development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (regulation of apoptotic process involved in development) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:22801495") "Any process that modulates the frequency, rate or extent of apoptotic process involved in development.") -AnnotationAssertion( "es") -AnnotationAssertion( "2015-10-19T15:02:28Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of apoptotic cell death involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of apoptotic cell death involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of apoptotic process involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of apoptotic process involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of apoptotic programmed cell death involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of apoptotic programmed cell death involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of programmed cell death by apoptosis involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of programmed cell death by apoptosis involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of activation of apoptosis involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of activation of apoptosis involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of apoptosis involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of apoptosis involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of apoptosis signaling involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of apoptosis signaling involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of apoptotic program involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of apoptotic program involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of type I programmed cell death involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of type I programmed cell death involved in development of an anatomical structure") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of apoptosis activator activity involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of apoptosis activator activity involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of commitment to apoptosis involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of commitment to apoptosis involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of induction of apoptosis by p53 involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of induction of apoptosis by p53 involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of induction of apoptosis involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of induction of apoptosis involved in development of an anatomical structure") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of signaling (initiator) caspase activity involved in anatomical structure development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of signaling (initiator) caspase activity involved in development of an anatomical structure") -AnnotationAssertion( "GO:1904748") -AnnotationAssertion(rdfs:comment "Q10943 in PMID:22801495, inferred from mutant phenotype") -AnnotationAssertion(rdfs:label "regulation of apoptotic process involved in development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (regulation of protein localization to nucleolus) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_telomere") Annotation( "GOC:TermGenie") Annotation( "GOC:nc") Annotation( "GO_REF:0000058") Annotation( "PMID:24415760") "Any process that modulates the frequency, rate or extent of protein localization to nucleolus.") -AnnotationAssertion( "nc") -AnnotationAssertion( "2015-10-19T15:16:17Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of protein localisation in nucleolus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of protein localisation to nucleolus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of protein localization in nucleolus") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904749") -AnnotationAssertion(rdfs:label "regulation of protein localization to nucleolus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of protein localization to nucleolus) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_telomere") Annotation( "GOC:TermGenie") Annotation( "GOC:nc") Annotation( "GO_REF:0000058") Annotation( "PMID:24415760") "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to nucleolus.") -AnnotationAssertion( "nc") -AnnotationAssertion( "2015-10-19T15:16:24Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of protein localisation in nucleolus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of protein localisation to nucleolus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of protein localization in nucleolus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of protein localization to nucleolus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of protein localisation in nucleolus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of protein localisation to nucleolus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of protein localization in nucleolus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of protein localization to nucleolus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of protein localisation in nucleolus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of protein localisation to nucleolus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of protein localization in nucleolus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of protein localization to nucleolus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of protein localisation in nucleolus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of protein localisation to nucleolus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of protein localization in nucleolus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of protein localisation in nucleolus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of protein localisation to nucleolus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of protein localization in nucleolus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of protein localization to nucleolus") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904750") -AnnotationAssertion(rdfs:label "negative regulation of protein localization to nucleolus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of protein localization to nucleolus) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_telomere") Annotation( "GOC:TermGenie") Annotation( "GOC:nc") Annotation( "GO_REF:0000058") Annotation( "PMID:24415760") "Any process that activates or increases the frequency, rate or extent of protein localization to nucleolus.") -AnnotationAssertion( "nc") -AnnotationAssertion( "2015-10-19T15:16:30Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of protein localisation in nucleolus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of protein localisation to nucleolus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of protein localization in nucleolus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of protein localisation in nucleolus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of protein localisation to nucleolus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of protein localization in nucleolus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of protein localization to nucleolus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of protein localisation in nucleolus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of protein localisation to nucleolus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of protein localization in nucleolus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of protein localization to nucleolus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of protein localisation in nucleolus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of protein localisation to nucleolus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of protein localization in nucleolus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of protein localization to nucleolus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of protein localisation in nucleolus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of protein localisation to nucleolus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of protein localization in nucleolus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of protein localization to nucleolus") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904751") -AnnotationAssertion(rdfs:label "positive regulation of protein localization to nucleolus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of vascular associated smooth muscle cell migration) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_miRNA") Annotation( "GOC:TermGenie") Annotation( "GOC:rph") Annotation( "GO_REF:0000058") Annotation( "PMID:20693317") "Any process that modulates the frequency, rate or extent of vascular associated smooth muscle cell migration.") -AnnotationAssertion( "rph") -AnnotationAssertion( "2015-10-19T15:49:52Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of vascular smooth muscle cell migration") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904752") -AnnotationAssertion(rdfs:label "regulation of vascular associated smooth muscle cell migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of vascular associated smooth muscle cell migration) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_miRNA") Annotation( "GOC:TermGenie") Annotation( "GOC:rph") Annotation( "GO_REF:0000058") Annotation( "PMID:20693317") "Any process that stops, prevents or reduces the frequency, rate or extent of vascular associated smooth muscle cell migration.") -AnnotationAssertion( "rph") -AnnotationAssertion( "2015-10-19T15:49:58Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of vascular associated smooth muscle cell migration") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of vascular smooth muscle cell migration") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of vascular associated smooth muscle cell migration") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of vascular smooth muscle cell migration") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of vascular associated smooth muscle cell migration") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of vascular smooth muscle cell migration") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of vascular smooth muscle cell migration") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of vascular associated smooth muscle cell migration") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of vascular smooth muscle cell migration") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904753") -AnnotationAssertion(rdfs:label "negative regulation of vascular associated smooth muscle cell migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of vascular associated smooth muscle cell migration) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_miRNA") Annotation( "GOC:TermGenie") Annotation( "GOC:rph") Annotation( "GO_REF:0000058") Annotation( "PMID:20693317") "Any process that activates or increases the frequency, rate or extent of vascular associated smooth muscle cell migration.") -AnnotationAssertion( "rph") -AnnotationAssertion( "2015-10-19T15:50:05Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of vascular smooth muscle cell migration") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of vascular associated smooth muscle cell migration") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of vascular smooth muscle cell migration") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of vascular associated smooth muscle cell migration") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of vascular smooth muscle cell migration") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of vascular associated smooth muscle cell migration") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of vascular smooth muscle cell migration") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of vascular associated smooth muscle cell migration") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of vascular smooth muscle cell migration") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904754") -AnnotationAssertion(rdfs:label "positive regulation of vascular associated smooth muscle cell migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (intramembranous bone morphogenesis) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000083") Annotation( "PMID:26399686") "The developmental process by which an intramembranous bone is generated and organized.") -AnnotationAssertion( "dos") -AnnotationAssertion( "2015-10-28T11:46:04Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "intramembranous bones morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "membrane bone morphogenesis") -AnnotationAssertion( "GO:1904770") -AnnotationAssertion(rdfs:label "intramembranous bone morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of protein localization to cell cortex) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:17115027") "Any process that modulates the frequency, rate or extent of protein localization to cell cortex.") -AnnotationAssertion( "es") -AnnotationAssertion( "2015-10-29T16:55:01Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of protein localisation to cell cortex") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904776") -AnnotationAssertion(rdfs:comment "An example is cye-1 in C. elegans, UniProt ID O01501 in PMID:17115027.") -AnnotationAssertion(rdfs:label "regulation of protein localization to cell cortex") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of protein localization to cell cortex) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:17115027") "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell cortex.") -AnnotationAssertion( "es") -AnnotationAssertion( "2015-10-29T16:55:08Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of protein localisation to cell cortex") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of protein localization to cell cortex") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of protein localisation to cell cortex") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of protein localization to cell cortex") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of protein localisation to cell cortex") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of protein localization to cell cortex") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of protein localisation to cell cortex") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of protein localisation to cell cortex") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of protein localization to cell cortex") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904777") -AnnotationAssertion(rdfs:comment "An example is cye-1 in C. elegans, UniProt ID O01501 in PMID:17115027.") -AnnotationAssertion(rdfs:label "negative regulation of protein localization to cell cortex") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of protein localization to cell cortex) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:17115027") "Any process that activates or increases the frequency, rate or extent of protein localization to cell cortex.") -AnnotationAssertion( "es") -AnnotationAssertion( "2015-10-29T16:55:15Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of protein localisation to cell cortex") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of protein localisation to cell cortex") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of protein localization to cell cortex") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of protein localisation to cell cortex") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of protein localization to cell cortex") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of protein localisation to cell cortex") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of protein localization to cell cortex") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of protein localisation to cell cortex") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of protein localization to cell cortex") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904778") -AnnotationAssertion(rdfs:comment "An example is cye-1 in C. elegans, UniProt ID O01501 in PMID:17115027.") -AnnotationAssertion(rdfs:label "positive regulation of protein localization to cell cortex") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of euchromatin binding) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_telomere") Annotation( "GOC:TermGenie") Annotation( "GOC:nc") Annotation( "GO_REF:0000059") Annotation( "PMID:22723415") "Any process that modulates the frequency, rate or extent of euchromatin binding.") -AnnotationAssertion( "nc") -AnnotationAssertion( "2015-11-09T11:43:04Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904793") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "regulation of euchromatin binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of euchromatin binding) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_telomere") Annotation( "GOC:TermGenie") Annotation( "GOC:nc") Annotation( "GO_REF:0000059") Annotation( "PMID:22723415") "Any process that stops, prevents or reduces the frequency, rate or extent of euchromatin binding.") -AnnotationAssertion( "nc") -AnnotationAssertion( "2015-11-09T11:43:12Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of euchromatin binding") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of euchromatin binding") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of euchromatin binding") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of euchromatin binding") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904794") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "negative regulation of euchromatin binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of euchromatin binding) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_telomere") Annotation( "GOC:TermGenie") Annotation( "GOC:nc") Annotation( "GO_REF:0000059") Annotation( "PMID:22723415") "Any process that activates or increases the frequency, rate or extent of euchromatin binding.") -AnnotationAssertion( "nc") -AnnotationAssertion( "2015-11-09T11:43:19Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of euchromatin binding") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of euchromatin binding") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of euchromatin binding") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of euchromatin binding") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904795") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "positive regulation of euchromatin binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of dense core granule transport) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:22699897") "Any process that modulates the frequency, rate or extent of dense core granule transport.") -AnnotationAssertion( "es") -AnnotationAssertion( "2015-11-11T10:40:10Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of dense core vesicle transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904809") -AnnotationAssertion(rdfs:comment "cdk-5 in C.elegans (G5ECH7) in PMID:22699897 (inferred from mutant phenotype).") -AnnotationAssertion(rdfs:label "regulation of dense core granule transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of dense core granule transport) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:22699897") "Any process that stops, prevents or reduces the frequency, rate or extent of dense core granule transport.") -AnnotationAssertion( "es") -AnnotationAssertion( "2015-11-11T10:40:18Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of dense core granule transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of dense core vesicle transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of dense core granule transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of dense core vesicle transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of dense core granule transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of dense core vesicle transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of dense core vesicle transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of dense core granule transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of dense core vesicle transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904810") -AnnotationAssertion(rdfs:comment "cdk-5 in C.elegans (G5ECH7) in PMID:22699897 (inferred from mutant phenotype).") -AnnotationAssertion(rdfs:label "negative regulation of dense core granule transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of dense core granule transport) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:22699897") "Any process that activates or increases the frequency, rate or extent of dense core granule transport.") -AnnotationAssertion( "es") -AnnotationAssertion( "2015-11-11T10:40:25Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of dense core vesicle transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of dense core granule transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of dense core vesicle transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of dense core granule transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of dense core vesicle transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of dense core granule transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of dense core vesicle transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of dense core granule transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of dense core vesicle transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904811") -AnnotationAssertion(rdfs:comment "cdk-5 in C.elegans (G5ECH7) in PMID:22699897 (inferred from mutant phenotype).") -AnnotationAssertion(rdfs:label "positive regulation of dense core granule transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (serous membrane development) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:dph") Annotation( "GO_REF:0000094") Annotation( "PMID:15840053") "The process whose specific outcome is the progression of a serous membrane over time, from its formation to the mature structure.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2015-11-17T19:00:01Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "tunica serosa development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "wall of serous sac development") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "serosa development") -AnnotationAssertion( "GO:1904817") -AnnotationAssertion(rdfs:label "serous membrane development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (visceral peritoneum development) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:dph") Annotation( "GO_REF:0000094") Annotation( "PMID:15840053") "The process whose specific outcome is the progression of a visceral peritoneum over time, from its formation to the mature structure.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2015-11-17T19:00:17Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904818") -AnnotationAssertion(rdfs:label "visceral peritoneum development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (parietal peritoneum development) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:dph") Annotation( "GO_REF:0000094") Annotation( "PMID:15840053") "The process whose specific outcome is the progression of a parietal peritoneum over time, from its formation to the mature structure.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2015-11-17T19:00:24Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "peritoneal cavity lining development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904819") -AnnotationAssertion(rdfs:label "parietal peritoneum development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (peritoneum development) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:dph") Annotation( "GO_REF:0000094") Annotation( "PMID:15840053") "The process whose specific outcome is the progression of a peritoneum over time, from its formation to the mature structure.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2015-11-18T17:23:51Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "peritonaeum development") -AnnotationAssertion( "GO:1904820") -AnnotationAssertion(rdfs:label "peritoneum development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (purine nucleobase transmembrane transport) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000069") "The process in which a purine nucleobase is transported across a membrane.") -AnnotationAssertion( "vw") -AnnotationAssertion( "2015-11-19T09:07:56Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904823") -AnnotationAssertion(rdfs:label "purine nucleobase transmembrane transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (regulation of aortic smooth muscle cell differentiation) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_miRNA") Annotation( "GOC:TermGenie") Annotation( "GOC:rph") Annotation( "GO_REF:0000058") Annotation( "PMID:22034194") "Any process that modulates the frequency, rate or extent of aortic smooth muscle cell differentiation.") -AnnotationAssertion( "rph") -AnnotationAssertion( "2015-11-24T10:20:40Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904829") -AnnotationAssertion(rdfs:label "regulation of aortic smooth muscle cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of aortic smooth muscle cell differentiation) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_miRNA") Annotation( "GOC:TermGenie") Annotation( "GOC:rph") Annotation( "GO_REF:0000058") Annotation( "PMID:22034194") "Any process that stops, prevents or reduces the frequency, rate or extent of aortic smooth muscle cell differentiation.") -AnnotationAssertion( "rph") -AnnotationAssertion( "2015-11-24T10:20:47Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of aortic smooth muscle cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of aortic smooth muscle cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of aortic smooth muscle cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of aortic smooth muscle cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904830") -AnnotationAssertion(rdfs:label "negative regulation of aortic smooth muscle cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of aortic smooth muscle cell differentiation) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_miRNA") Annotation( "GOC:TermGenie") Annotation( "GOC:rph") Annotation( "GO_REF:0000058") Annotation( "PMID:22034194") "Any process that activates or increases the frequency, rate or extent of aortic smooth muscle cell differentiation.") -AnnotationAssertion( "rph") -AnnotationAssertion( "2015-11-24T10:20:54Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of aortic smooth muscle cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of aortic smooth muscle cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of aortic smooth muscle cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of aortic smooth muscle cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904831") -AnnotationAssertion(rdfs:label "positive regulation of aortic smooth muscle cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (dorsal root ganglion morphogenesis) - -AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:TermGenie") Annotation( "GOC:bf") Annotation( "GO_REF:0000083") Annotation( "PMID:18936100") "The developmental process by which a dorsal root ganglion is generated and organized.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2015-12-01T16:41:17Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "ganglion of dorsal root morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "ganglion spinalis morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "spinal ganglion morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "spinal ganglion part of peripheral nervous system morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "DRG morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "dorsal root ganglia morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "ganglion sensorium nervi spinalis morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "ganglion spinale morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "posterior root ganglion morphogenesis") -AnnotationAssertion( "GO:1904835") -AnnotationAssertion(rdfs:label "dorsal root ganglion morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (facioacoustic ganglion morphogenesis) - -AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:TermGenie") Annotation( "GOC:bf") Annotation( "GOC:mat") Annotation( "GO_REF:0000083") Annotation( "PMID:18356247") "The developmental process by which an acoustico-facial VII-VIII ganglion complex is generated and organized.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2015-12-01T17:02:06Z") -AnnotationAssertion(Annotation( "UBERON:0012175") "acoustico-facial VII-VIII ganglion complex morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "acousticofacial ganglion morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "facio-acoustic ganglion complex VII-VIII morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "facio-acoustic ganglion morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "facio-acoustic VII-VIII ganglion complex morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "facio-acoustic ganglion complex morphogenesis") -AnnotationAssertion( "GO:1904836") -AnnotationAssertion(rdfs:label "facioacoustic ganglion morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (excitatory synapse assembly) - -AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:TermGenie") Annotation( "GOC:bf") Annotation( "GO_REF:0000079") Annotation( "PMID:21670302") "The aggregation, arrangement and bonding together of a set of components to form an excitatory synapse.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2015-12-17T10:31:26Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "excitatory synapse formation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904861") -AnnotationAssertion(rdfs:label "excitatory synapse assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (ventral tegmental area development) - -AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:TermGenie") Annotation( "GOC:bf") Annotation( "GO_REF:0000094") Annotation( "PMID:26548362") "The process whose specific outcome is the progression of a ventral tegmental area (VTA) over time, from its formation to the mature structure.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2015-12-17T14:44:18Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "VTA development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "a10a development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "ventral tegmental area of tsai development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "ventral tegmental nucleus (tsai) development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "ventral tegmental nucleus of tsai development") -AnnotationAssertion(Annotation( "Wikipedia:Ventral_tegmental_area") "ventral tegmentum development") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "area tegmentalis ventralis (Tsai) development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "area tegmentalis ventralis development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "tegmentum ventrale development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "ventral brain stem development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "ventral tegmental area (Tsai) development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "ventral tegmental nucleus (Rioch) development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "ventromedial mesencephalic tegmentum development") -AnnotationAssertion( "GO:1904866") -AnnotationAssertion(rdfs:label "ventral tegmental area development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cranial skeletal system development) - -AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:TermGenie") Annotation( "GOC:bf") Annotation( "GO_REF:0000094") Annotation( "PMID:11262227") "The process whose specific outcome is the progression of a cranial skeletal system over time, from its formation to the mature structure. The cranial skeletal system is the skeletal subdivision of the head, and includes the skull (cranium plus mandible), pharyngeal and/or hyoid apparatus.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2016-01-07T13:45:06Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "cranial skeleton development") -AnnotationAssertion(Annotation( "PMID:11262227") "craniofacial development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "osteocranium development") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "cranium development") -AnnotationAssertion( "GO:1904888") -AnnotationAssertion(rdfs:label "cranial skeletal system development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of excitatory synapse assembly) - -AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:TermGenie") Annotation( "GOC:bf") Annotation( "GO_REF:0000058") "Any process that modulates the frequency, rate or extent of excitatory synapse assembly.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2016-01-07T14:35:53Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of excitatory synapse formation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904889") -AnnotationAssertion(rdfs:label "regulation of excitatory synapse assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of excitatory synapse assembly) - -AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:TermGenie") Annotation( "GOC:bf") Annotation( "GO_REF:0000058") "Any process that stops, prevents or reduces the frequency, rate or extent of excitatory synapse assembly.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2016-01-07T14:36:00Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of excitatory synapse assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of excitatory synapse formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of excitatory synapse assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of excitatory synapse formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of excitatory synapse assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of excitatory synapse formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of excitatory synapse formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of excitatory synapse assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of excitatory synapse formation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904890") -AnnotationAssertion(rdfs:label "negative regulation of excitatory synapse assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of excitatory synapse assembly) - -AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:TermGenie") Annotation( "GOC:bf") Annotation( "GO_REF:0000058") Annotation( "PMID:21670302") "Any process that activates or increases the frequency, rate or extent of excitatory synapse assembly.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2016-01-07T14:36:07Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of excitatory synapse formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of excitatory synapse assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of excitatory synapse formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of excitatory synapse assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of excitatory synapse formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of excitatory synapse assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of excitatory synapse formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of excitatory synapse assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of excitatory synapse formation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904891") -AnnotationAssertion(rdfs:label "positive regulation of excitatory synapse assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of hepatic stellate cell proliferation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:15358192") "Any process that modulates the frequency, rate or extent of hepatic stellate cell proliferation.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2016-01-14T15:56:59Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of Ito cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of hepatic perisinusoidal cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of perisinusoidal cell proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904897") -AnnotationAssertion(rdfs:label "regulation of hepatic stellate cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of hepatic stellate cell proliferation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:15358192") "Any process that stops, prevents or reduces the frequency, rate or extent of hepatic stellate cell proliferation.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2016-01-14T15:57:06Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of Ito cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of hepatic perisinusoidal cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of hepatic stellate cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of perisinusoidal cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of Ito cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of hepatic perisinusoidal cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of hepatic stellate cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of perisinusoidal cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of Ito cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of hepatic perisinusoidal cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of hepatic stellate cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of perisinusoidal cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of Ito cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of hepatic perisinusoidal cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of perisinusoidal cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of Ito cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of hepatic perisinusoidal cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of hepatic stellate cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of perisinusoidal cell proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904898") -AnnotationAssertion(rdfs:label "negative regulation of hepatic stellate cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of hepatic stellate cell proliferation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:15358192") "Any process that activates or increases the frequency, rate or extent of hepatic stellate cell proliferation.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2016-01-14T15:57:13Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of Ito cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of hepatic perisinusoidal cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of perisinusoidal cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of Ito cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of hepatic perisinusoidal cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of hepatic stellate cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of perisinusoidal cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of Ito cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of hepatic perisinusoidal cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of hepatic stellate cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of perisinusoidal cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of Ito cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of hepatic perisinusoidal cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of hepatic stellate cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of perisinusoidal cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of Ito cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of hepatic perisinusoidal cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of hepatic stellate cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of perisinusoidal cell proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904899") -AnnotationAssertion(rdfs:label "positive regulation of hepatic stellate cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of cell proliferation in midbrain) - -AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:TermGenie") Annotation( "GOC:bf") Annotation( "GO_REF:0000058") Annotation( "PMID:18953410") Annotation( "PMID:24431302") "Any process that modulates the frequency, rate or extent of cell proliferation in midbrain.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2016-02-01T13:16:11Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of cell proliferation in mesencephalon") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of mesencepahalic cell proliferation") -AnnotationAssertion( "GO:1904933") -AnnotationAssertion(rdfs:label "regulation of cell proliferation in midbrain") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of cell proliferation in midbrain) - -AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:TermGenie") Annotation( "GOC:bf") Annotation( "GO_REF:0000058") Annotation( "PMID:18953410") Annotation( "PMID:24431302") "Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation in midbrain.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2016-02-01T13:16:19Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of cell proliferation in mesencephalon") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of cell proliferation in midbrain") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of cell proliferation in mesencephalon") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of cell proliferation in midbrain") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of cell proliferation in mesencephalon") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of cell proliferation in midbrain") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of cell proliferation in mesencephalon") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of cell proliferation in mesencephalon") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of cell proliferation in midbrain") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of mesencepahalic cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of mesencepahalic cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of mesencepahalic cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of mesencepahalic cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of mesencepahalic cell proliferation") -AnnotationAssertion( "GO:1904934") -AnnotationAssertion(rdfs:label "negative regulation of cell proliferation in midbrain") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of cell proliferation in midbrain) - -AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:TermGenie") Annotation( "GOC:bf") Annotation( "GO_REF:0000058") Annotation( "PMID:24431302") "Any process that activates or increases the frequency, rate or extent of cell proliferation in midbrain.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2016-02-01T13:16:27Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of cell proliferation in mesencephalon") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of cell proliferation in mesencephalon") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of cell proliferation in midbrain") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of cell proliferation in mesencephalon") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of cell proliferation in midbrain") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of cell proliferation in mesencephalon") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of cell proliferation in midbrain") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of cell proliferation in mesencephalon") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of cell proliferation in midbrain") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of mesencepahalic cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of mesencepahalic cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of mesencepahalic cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of mesencepahalic cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of mesencepahalic cell proliferation") -AnnotationAssertion( "GO:1904935") -AnnotationAssertion(rdfs:label "positive regulation of cell proliferation in midbrain") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (interneuron migration) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:ah") Annotation( "GO_REF:0000091") Annotation( "PMID:18622031") "The orderly movement of an interneuron from one site to another.") -AnnotationAssertion( "ah") -AnnotationAssertion( "2016-02-01T14:04:32Z") -AnnotationAssertion(Annotation( "GOC:ah") "inter neuron migration") -AnnotationAssertion(Annotation( "GOC:ah") "inter-neuron migration") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904936") -AnnotationAssertion(rdfs:label "interneuron migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (sensory neuron migration) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:ah") Annotation( "GO_REF:0000091") Annotation( "PMID:18622031") "The orderly movement of a sensory neuron from one site to another.") -AnnotationAssertion( "ah") -AnnotationAssertion( "2016-02-01T14:15:50Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904937") -AnnotationAssertion(rdfs:label "sensory neuron migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of cardiac ventricle formation) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_miRNA") Annotation( "GOC:TermGenie") Annotation( "GOC:bc") Annotation( "GO_REF:0000058") Annotation( "PMID:23575307") "Any process that modulates the frequency, rate or extent of cardiac ventricle formation.") -AnnotationAssertion( "bc") -AnnotationAssertion( "2016-02-02T16:37:16Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904942") -AnnotationAssertion(rdfs:label "regulation of cardiac ventricle formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of cardiac ventricle formation) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_miRNA") Annotation( "GOC:TermGenie") Annotation( "GOC:bc") Annotation( "GO_REF:0000058") Annotation( "PMID:23575307") "Any process that stops, prevents or reduces the frequency, rate or extent of cardiac ventricle formation.") -AnnotationAssertion( "bc") -AnnotationAssertion( "2016-02-02T16:37:24Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of cardiac ventricle formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of cardiac ventricle formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of cardiac ventricle formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of cardiac ventricle formation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904943") -AnnotationAssertion(rdfs:label "negative regulation of cardiac ventricle formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of cardiac ventricle formation) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_miRNA") Annotation( "GOC:TermGenie") Annotation( "GOC:bc") Annotation( "GO_REF:0000058") Annotation( "PMID:23575307") "Any process that activates or increases the frequency, rate or extent of cardiac ventricle formation.") -AnnotationAssertion( "bc") -AnnotationAssertion( "2016-02-02T16:37:31Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of cardiac ventricle formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of cardiac ventricle formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of cardiac ventricle formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of cardiac ventricle formation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904944") -AnnotationAssertion(rdfs:label "positive regulation of cardiac ventricle formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (midbrain dopaminergic neuron differentiation) - -AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:TermGenie") Annotation( "GOC:bf") Annotation( "GO_REF:0000086") Annotation( "PMID:17331494") Annotation( "PMID:19122665") "The process in which a relatively unspecialized cell acquires the specialized features of a midbrain dopaminergic neuron.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2016-02-04T14:38:10Z") -AnnotationAssertion(Annotation( "PMID:19122665") "DA neurogenesis from midbrain floor plate") -AnnotationAssertion(Annotation( "PMID:24287202") "mDA neuron differentiation") -AnnotationAssertion(Annotation( "PMID:19122665") "midbrain DA neurogenesis") -AnnotationAssertion(Annotation( "PMID:19122665") "midbrain dopaminergic neuron production") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904948") -AnnotationAssertion(rdfs:label "midbrain dopaminergic neuron differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (negative regulation of establishment of protein localization) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:22761445") "Any process that stops, prevents or reduces the frequency, rate or extent of establishment of protein localization.") -AnnotationAssertion( "mec") -AnnotationAssertion( "2016-02-05T09:59:24Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of establishment of protein localisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of establishment of protein localization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of protein positioning") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of protein recruitment") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of establishment of protein localisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of establishment of protein localization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of protein positioning") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of protein recruitment") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of establishment of protein localisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of establishment of protein localization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of protein positioning") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of protein recruitment") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of establishment of protein localisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of protein positioning") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of protein recruitment") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of establishment of protein localisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of establishment of protein localization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of protein positioning") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of protein recruitment") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904950") -AnnotationAssertion(rdfs:label "negative regulation of establishment of protein localization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of establishment of protein localization) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:22761445") "Any process that activates or increases the frequency, rate or extent of establishment of protein localization.") -AnnotationAssertion( "mec") -AnnotationAssertion( "2016-02-05T09:59:32Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of establishment of protein localisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of protein positioning") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of protein recruitment") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of establishment of protein localisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of establishment of protein localization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of protein positioning") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of protein recruitment") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of establishment of protein localisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of establishment of protein localization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of protein positioning") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of protein recruitment") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of establishment of protein localisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of establishment of protein localization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of protein positioning") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of protein recruitment") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of establishment of protein localisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of establishment of protein localization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of protein positioning") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of protein recruitment") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904951") -AnnotationAssertion(rdfs:label "positive regulation of establishment of protein localization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of midbrain dopaminergic neuron differentiation) - -AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:TermGenie") Annotation( "GOC:bf") Annotation( "GO_REF:0000058") Annotation( "PMID:21347250") "Any process that modulates the frequency, rate or extent of midbrain dopaminergic neuron differentiation.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2016-02-09T12:00:21Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of DA neurogenesis from midbrain floor plate") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of mDA neuron differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of midbrain DA neurogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of midbrain dopaminergic neuron production") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904956") -AnnotationAssertion(rdfs:label "regulation of midbrain dopaminergic neuron differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of midbrain dopaminergic neuron differentiation) - -AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:TermGenie") Annotation( "GOC:bf") Annotation( "GO_REF:0000058") "Any process that stops, prevents or reduces the frequency, rate or extent of midbrain dopaminergic neuron differentiation.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2016-02-09T12:00:29Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of DA neurogenesis from midbrain floor plate") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of mDA neuron differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of midbrain DA neurogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of midbrain dopaminergic neuron differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of midbrain dopaminergic neuron production") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of DA neurogenesis from midbrain floor plate") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of mDA neuron differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of midbrain DA neurogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of midbrain dopaminergic neuron differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of midbrain dopaminergic neuron production") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of DA neurogenesis from midbrain floor plate") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of mDA neuron differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of midbrain DA neurogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of midbrain dopaminergic neuron differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of midbrain dopaminergic neuron production") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of DA neurogenesis from midbrain floor plate") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of mDA neuron differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of midbrain DA neurogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of midbrain dopaminergic neuron production") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of DA neurogenesis from midbrain floor plate") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of mDA neuron differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of midbrain DA neurogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of midbrain dopaminergic neuron differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of midbrain dopaminergic neuron production") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904957") -AnnotationAssertion(rdfs:label "negative regulation of midbrain dopaminergic neuron differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of midbrain dopaminergic neuron differentiation) - -AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:TermGenie") Annotation( "GOC:bf") Annotation( "GO_REF:0000058") Annotation( "PMID:21347250") "Any process that activates or increases the frequency, rate or extent of midbrain dopaminergic neuron differentiation.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2016-02-09T12:00:36Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of DA neurogenesis from midbrain floor plate") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of mDA neuron differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of midbrain DA neurogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of midbrain dopaminergic neuron production") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of DA neurogenesis from midbrain floor plate") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of mDA neuron differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of midbrain DA neurogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of midbrain dopaminergic neuron differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of midbrain dopaminergic neuron production") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of DA neurogenesis from midbrain floor plate") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of mDA neuron differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of midbrain DA neurogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of midbrain dopaminergic neuron differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of midbrain dopaminergic neuron production") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of DA neurogenesis from midbrain floor plate") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of mDA neuron differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of midbrain DA neurogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of midbrain dopaminergic neuron differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of midbrain dopaminergic neuron production") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of DA neurogenesis from midbrain floor plate") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of mDA neuron differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of midbrain DA neurogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of midbrain dopaminergic neuron differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of midbrain dopaminergic neuron production") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904958") -AnnotationAssertion(rdfs:label "positive regulation of midbrain dopaminergic neuron differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (slow muscle cell migration) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:ymb") Annotation( "GO_REF:0000091") Annotation( "PMID:14667409") Annotation( "PMID:15572133") Annotation( "PMID:25534553") "The orderly movement of a slow muscle cell from one site to another.") -AnnotationAssertion( "ymb") -AnnotationAssertion( "2016-02-16T21:20:11Z") -AnnotationAssertion(Annotation( "PMID:14667409") "slow-twitch muscle cell migration") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904969") -AnnotationAssertion(rdfs:comment "The directional migration of a slow muscle cell from one site to another within the embryo.") -AnnotationAssertion(rdfs:label "slow muscle cell migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (lymphatic endothelial cell migration) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000091") Annotation( "PMID:25745057") "The orderly movement of a lymphatic endothelial cell from one site to another in the wall of a lymphatic vessel.") -AnnotationAssertion( "dgh") -AnnotationAssertion( "2016-02-18T20:49:43Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904977") -AnnotationAssertion(rdfs:label "lymphatic endothelial cell migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (regulation of endothelial cell activation) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_miRNA") Annotation( "GOC:TermGenie") Annotation( "GOC:bc") Annotation( "GO_REF:0000058") Annotation( "PMID:24255059") "Any process that modulates the frequency, rate or extent of endothelial cell activation.") -AnnotationAssertion( "bc") -AnnotationAssertion( "2016-02-29T16:16:09Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904987") -AnnotationAssertion(rdfs:label "regulation of endothelial cell activation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of endothelial cell activation) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_miRNA") Annotation( "GOC:TermGenie") Annotation( "GOC:bc") Annotation( "GO_REF:0000058") Annotation( "PMID:24255059") "Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell activation.") -AnnotationAssertion( "bc") -AnnotationAssertion( "2016-02-29T16:16:18Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of endothelial cell activation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of endothelial cell activation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of endothelial cell activation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of endothelial cell activation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904988") -AnnotationAssertion(rdfs:label "negative regulation of endothelial cell activation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of endothelial cell activation) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_miRNA") Annotation( "GOC:TermGenie") Annotation( "GOC:bc") Annotation( "GO_REF:0000058") Annotation( "PMID:24255059") "Any process that activates or increases the frequency, rate or extent of endothelial cell activation.") -AnnotationAssertion( "bc") -AnnotationAssertion( "2016-02-29T16:16:25Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of endothelial cell activation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of endothelial cell activation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of endothelial cell activation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of endothelial cell activation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1904989") -AnnotationAssertion(rdfs:label "positive regulation of endothelial cell activation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (transmembrane phosphate ion transport from cytosol to vacuole) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000078") Annotation( "PMID:26554016") "The directed movement of phosphate ions from the cytosol across the vacuolar membrane and into the vacuolar lumen.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2016-03-03T00:34:12Z") -AnnotationAssertion( "GO:0007037") -AnnotationAssertion( "vacuolar phosphate transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905011") -AnnotationAssertion(rdfs:label "transmembrane phosphate ion transport from cytosol to vacuole") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (regulation of membrane lipid metabolic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:25954280") "Any process that modulates the frequency, rate or extent of membrane lipid metabolic process.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2016-03-08T20:41:32Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of membrane lipid metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905038") -AnnotationAssertion(rdfs:label "regulation of membrane lipid metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (carboxylic acid transmembrane transport) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000069") Annotation( "PMID:10869563") "The process in which carboxylic acid is transported across a membrane.") -AnnotationAssertion( "vw") -AnnotationAssertion( "2016-03-09T15:33:53Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905039") -AnnotationAssertion(rdfs:label "carboxylic acid transmembrane transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (otic placode development) - -AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:TermGenie") Annotation( "GOC:bf") Annotation( "GOC:mat") Annotation( "GO_REF:0000094") Annotation( "PMID:18356247") "The process whose specific outcome is the progression of an otic placode over time, from its formation to the mature structure.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2016-03-10T09:30:20Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "placoda otica development") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "auditory placode development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "ear placode development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "ear/otic placode development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "octaval VIII placode development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "octaval placode development") -AnnotationAssertion( "GO:1905040") -AnnotationAssertion(rdfs:label "otic placode development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of vascular associated smooth muscle cell differentiation) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_miRNA") Annotation( "GOC:TermGenie") Annotation( "GOC:rph") Annotation( "GO_REF:0000058") Annotation( "PMID:19088079") "Any process that modulates the frequency, rate or extent of vascular smooth muscle cell differentiation.") -AnnotationAssertion( "rph") -AnnotationAssertion( "2016-03-21T11:14:53Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of VSMC differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of vascular smooth muscle cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905063") -AnnotationAssertion(rdfs:label "regulation of vascular associated smooth muscle cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of vascular associated smooth muscle cell differentiation) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_miRNA") Annotation( "GOC:TermGenie") Annotation( "GOC:rph") Annotation( "GO_REF:0000058") Annotation( "PMID:19088079") "Any process that stops, prevents or reduces the frequency, rate or extent of vascular smooth muscle cell differentiation.") -AnnotationAssertion( "rph") -AnnotationAssertion( "2016-03-21T11:15:03Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of VSMC differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of vascular associated smooth muscle cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of vascular smooth muscle cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of VSMC differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of vascular associated smooth muscle cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of vascular smooth muscle cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of VSMC differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of vascular associated smooth muscle cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of vascular smooth muscle cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of VSMC differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of vascular smooth muscle cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of VSMC differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of vascular associated smooth muscle cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of vascular smooth muscle cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905064") -AnnotationAssertion(rdfs:label "negative regulation of vascular associated smooth muscle cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of vascular associated smooth muscle cell differentiation) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_miRNA") Annotation( "GOC:TermGenie") Annotation( "GOC:rph") Annotation( "GO_REF:0000058") Annotation( "PMID:19088079") "Any process that activates or increases the frequency, rate or extent of vascular smooth muscle cell differentiation.") -AnnotationAssertion( "rph") -AnnotationAssertion( "2016-03-21T11:15:13Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of VSMC differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of vascular smooth muscle cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of VSMC differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of vascular associated smooth muscle cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of vascular smooth muscle cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of VSMC differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of vascular associated smooth muscle cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of vascular smooth muscle cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of VSMC differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of vascular associated smooth muscle cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of vascular smooth muscle cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of VSMC differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of vascular associated smooth muscle cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of vascular smooth muscle cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905065") -AnnotationAssertion(rdfs:label "positive regulation of vascular associated smooth muscle cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (allantois development) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000094") Annotation( "PMID:17440924") Annotation( "PMID:21470579") "The process whose specific outcome is the progression of an allantois over time, from its formation to the mature structure.") -AnnotationAssertion( "cls") -AnnotationAssertion( "2016-03-21T15:18:21Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "allantoic bud development") -AnnotationAssertion( "GO:1905069") -AnnotationAssertion(rdfs:label "allantois development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (anterior visceral endoderm cell migration) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000091") Annotation( "PMID:17078044") "The orderly movement of an anterior visceral endoderm cell from one site to another.") -AnnotationAssertion( "cls") -AnnotationAssertion( "2016-03-21T15:18:32Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905070") -AnnotationAssertion(rdfs:label "anterior visceral endoderm cell migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (tight junction disassembly) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "GO_REF:0000079") Annotation( "PMID:18718461") "The disaggregation of an tight junction into its constituent components.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2016-03-23T12:35:08Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "occluding cell junction disassembly") -AnnotationAssertion( "occluding junction disassembly") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905071") -AnnotationAssertion(rdfs:label "tight junction disassembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cardiac jelly development) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "GO_REF:0000094") Annotation( "PMID:10645959") Annotation( "PMID:16314491") Annotation( "PMID:19703439") "The process whose specific outcome is the progression of cardiac jelly over time, from its formation to the mature structure. The cardiac jelly is an acellular gelatinous matrix secreted by the myocardium and plays a central role in the septation of the heart.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2016-03-23T13:17:59Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "heart cardiac jelly development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905072") -AnnotationAssertion(rdfs:label "cardiac jelly development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (regulation of tight junction disassembly) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "GO_REF:0000058") Annotation( "PMID:18718461") "Any process that modulates the frequency, rate or extent of tight junction disassembly.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2016-03-23T19:32:51Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of occluding cell junction disassembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of occluding junction disassembly") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905073") -AnnotationAssertion(rdfs:label "regulation of tight junction disassembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of tight junction disassembly) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "GO_REF:0000058") Annotation( "PMID:18718461") "Any process that stops, prevents or reduces the frequency, rate or extent of tight junction disassembly.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2016-03-23T19:33:01Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of occluding cell junction disassembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of tight junction disassembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of occluding cell junction disassembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of tight junction disassembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of occluding cell junction disassembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of occluding junction disassembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of tight junction disassembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of occluding cell junction disassembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of occluding cell junction disassembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of occluding junction disassembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of tight junction disassembly") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905074") -AnnotationAssertion(rdfs:label "negative regulation of tight junction disassembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of tight junction disassembly) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "GO_REF:0000058") Annotation( "PMID:18718461") "Any process that activates or increases the frequency, rate or extent of tight junction disassembly.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2016-03-23T19:33:10Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of occluding cell junction disassembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of occluding junction disassembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of occluding cell junction disassembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of tight junction disassembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of occluding cell junction disassembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of tight junction disassembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of occluding cell junction disassembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of tight junction disassembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of occluding cell junction disassembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of occluding junction disassembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of tight junction disassembly") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905075") -AnnotationAssertion(rdfs:label "positive regulation of tight junction disassembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of cerebellar neuron development) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:26609159") "Any process that modulates the frequency, rate or extent of cerebellar neuron development.") -AnnotationAssertion( "hjd") -AnnotationAssertion( "2016-03-24T19:45:17Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905079") -AnnotationAssertion(rdfs:label "regulation of cerebellar neuron development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (negative regulation of cerebellar neuron development) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:26609159") "Any process that stops, prevents or reduces the frequency, rate or extent of cerebellar neuron development.") -AnnotationAssertion( "hjd") -AnnotationAssertion( "2016-03-24T19:45:26Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of cerebellar neuron development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of cerebellar neuron development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of cerebellar neuron development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of cerebellar neuron development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905080") -AnnotationAssertion(rdfs:label "negative regulation of cerebellar neuron development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of cerebellar neuron development) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:26609159") "Any process that activates or increases the frequency, rate or extent of cerebellar neuron development.") -AnnotationAssertion( "hjd") -AnnotationAssertion( "2016-03-24T19:45:35Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of cerebellar neuron development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of cerebellar neuron development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of cerebellar neuron development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of cerebellar neuron development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905081") -AnnotationAssertion(rdfs:label "positive regulation of cerebellar neuron development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (regulation of axo-dendritic protein transport) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:20694152") "Any process that modulates the frequency, rate or extent of axo-dendritic protein transport.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2016-04-11T20:38:31Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of axonal protein transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905126") -AnnotationAssertion(rdfs:label "regulation of axo-dendritic protein transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of axo-dendritic protein transport) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:20694152") "Any process that stops, prevents or reduces the frequency, rate or extent of axo-dendritic protein transport.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2016-04-11T20:38:40Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of axo-dendritic protein transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of axo-dendritic protein transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of axo-dendritic protein transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of axonal protein transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of axonal protein transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of axonal protein transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of axo-dendritic protein transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of axonal protein transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of axonal protein transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905127") -AnnotationAssertion(rdfs:label "negative regulation of axo-dendritic protein transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of axo-dendritic protein transport) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:20694152") "Any process that activates or increases the frequency, rate or extent of axo-dendritic protein transport.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2016-04-11T20:38:48Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of axo-dendritic protein transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of axo-dendritic protein transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of axo-dendritic protein transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of axo-dendritic protein transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of axonal protein transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of axonal protein transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of axonal protein transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of axonal protein transport") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of axonal protein transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905128") -AnnotationAssertion(rdfs:label "positive regulation of axo-dendritic protein transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (apical ectodermal ridge formation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000081") Annotation( "PMID:18359901") Annotation( "PMID:9323126") Annotation( "PMID:9596583") "The process that gives rise to the apical ectodermal ridge. This process pertains to the initial formation of a structure from unspecified parts.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2016-04-13T11:46:40Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "apical epidermal ridge formation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "AER formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "crista ectodermalis apicalis formation") -AnnotationAssertion( "GO:1905139") -AnnotationAssertion(rdfs:label "apical ectodermal ridge formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (regulation of apical ectodermal ridge formation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:18359901") "Any process that modulates the frequency, rate or extent of apical ectodermal ridge formation.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2016-04-13T12:16:40Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of apical epidermal ridge formation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of AER formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of crista ectodermalis apicalis formation") -AnnotationAssertion( "GO:1905140") -AnnotationAssertion(rdfs:label "regulation of apical ectodermal ridge formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (negative regulation of apical ectodermal ridge formation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:18359901") "Any process that stops, prevents or reduces the frequency, rate or extent of apical ectodermal ridge formation.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2016-04-13T12:16:48Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of apical ectodermal ridge formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of apical epidermal ridge formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of apical ectodermal ridge formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of apical epidermal ridge formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of apical ectodermal ridge formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of apical epidermal ridge formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of apical epidermal ridge formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of apical ectodermal ridge formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of apical epidermal ridge formation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of AER formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of crista ectodermalis apicalis formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of AER formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of crista ectodermalis apicalis formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of AER formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of crista ectodermalis apicalis formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of AER formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of crista ectodermalis apicalis formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of AER formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of crista ectodermalis apicalis formation") -AnnotationAssertion( "GO:1905141") -AnnotationAssertion(rdfs:label "negative regulation of apical ectodermal ridge formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of apical ectodermal ridge formation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:18359901") "Any process that activates or increases the frequency, rate or extent of apical ectodermal ridge formation.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2016-04-13T12:16:57Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of apical epidermal ridge formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of apical ectodermal ridge formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of apical epidermal ridge formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of apical ectodermal ridge formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of apical epidermal ridge formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of apical ectodermal ridge formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of apical epidermal ridge formation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of AER formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of AER formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of crista ectodermalis apicalis formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of AER formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of crista ectodermalis apicalis formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of AER formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of crista ectodermalis apicalis formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of AER formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of crista ectodermalis apicalis formation") -AnnotationAssertion( "GO:1905142") -AnnotationAssertion(rdfs:label "positive regulation of apical ectodermal ridge formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (response to acetylcholine) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000071") Annotation( "PMID:21238497") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetylcholine stimulus.") -AnnotationAssertion( "dos") -AnnotationAssertion( "2016-04-14T08:54:49Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905144") -AnnotationAssertion(rdfs:label "response to acetylcholine") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cellular response to acetylcholine) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000071") Annotation( "PMID:21238497") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetylcholine stimulus.") -AnnotationAssertion( "dos") -AnnotationAssertion( "2016-04-14T08:54:58Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905145") -AnnotationAssertion(rdfs:label "cellular response to acetylcholine") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (lysosomal protein catabolic process) - -AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:TermGenie") Annotation( "GOC:bf") Annotation( "GO_REF:0000062") Annotation( "PMID:24334770") "Any cellular protein catabolic process that takes place in a lysosome.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2016-04-14T12:50:34Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "cellular protein breakdown in lysosome") -AnnotationAssertion( "cellular protein catabolic process in lysosome") -AnnotationAssertion(Annotation( "GOC:TermGenie") "cellular protein catabolism in lysosome") -AnnotationAssertion(Annotation( "GOC:TermGenie") "cellular protein degradation in lysosome") -AnnotationAssertion(Annotation( "GOC:bf") "lysosomal protein catabolism") -AnnotationAssertion(Annotation( "GOC:bf") "lysosomal protein degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "PMID:24334770") "lysosomal proteolysis") -AnnotationAssertion(Annotation( "GOC:bf") "proteolysis within lysosome") -AnnotationAssertion( "GO:1905146") -AnnotationAssertion(rdfs:comment "Also consider annotating to the term 'autophagy ; GO:0006914' or one of its descendants.") -AnnotationAssertion(rdfs:label "lysosomal protein catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of smooth muscle hypertrophy) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_miRNA") Annotation( "GOC:TermGenie") Annotation( "GOC:bc") Annotation( "GO_REF:0000058") Annotation( "PMID:22161164") "Any process that modulates the frequency, rate or extent of smooth muscle hypertrophy.") -AnnotationAssertion( "bc") -AnnotationAssertion( "2016-04-15T12:47:07Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905147") -AnnotationAssertion(rdfs:label "regulation of smooth muscle hypertrophy") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of smooth muscle hypertrophy) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_miRNA") Annotation( "GOC:TermGenie") Annotation( "GOC:bc") Annotation( "GO_REF:0000058") Annotation( "PMID:22161164") "Any process that stops, prevents or reduces the frequency, rate or extent of smooth muscle hypertrophy.") -AnnotationAssertion( "bc") -AnnotationAssertion( "2016-04-15T12:47:16Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of smooth muscle hypertrophy") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of smooth muscle hypertrophy") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of smooth muscle hypertrophy") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of smooth muscle hypertrophy") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905148") -AnnotationAssertion(rdfs:label "negative regulation of smooth muscle hypertrophy") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of smooth muscle hypertrophy) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_miRNA") Annotation( "GOC:TermGenie") Annotation( "GOC:bc") Annotation( "GO_REF:0000058") Annotation( "PMID:22161164") "Any process that activates or increases the frequency, rate or extent of smooth muscle hypertrophy.") -AnnotationAssertion( "bc") -AnnotationAssertion( "2016-04-15T12:47:24Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of smooth muscle hypertrophy") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of smooth muscle hypertrophy") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of smooth muscle hypertrophy") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of smooth muscle hypertrophy") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905149") -AnnotationAssertion(rdfs:label "positive regulation of smooth muscle hypertrophy") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of membrane invagination) - -AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:TermGenie") Annotation( "GOC:bf") Annotation( "GO_REF:0000058") Annotation( "PMID:26589353") "Any process that modulates the frequency, rate or extent of membrane invagination.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2016-04-18T15:43:54Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905153") -AnnotationAssertion(rdfs:label "regulation of membrane invagination") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of membrane invagination) - -AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:TermGenie") Annotation( "GOC:bf") Annotation( "GO_REF:0000058") Annotation( "PMID:26589353") "Any process that stops, prevents or reduces the frequency, rate or extent of membrane invagination.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2016-04-18T15:44:04Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of membrane invagination") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of membrane invagination") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of membrane invagination") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of membrane invagination") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905154") -AnnotationAssertion(rdfs:label "negative regulation of membrane invagination") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of membrane invagination) - -AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:TermGenie") Annotation( "GOC:bf") Annotation( "GO_REF:0000058") "Any process that activates or increases the frequency, rate or extent of membrane invagination.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2016-04-18T15:44:12Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of membrane invagination") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of membrane invagination") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of membrane invagination") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of membrane invagination") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905155") -AnnotationAssertion(rdfs:label "positive regulation of membrane invagination") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of lysosomal protein catabolic process) - -AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:TermGenie") Annotation( "GOC:bf") Annotation( "GO_REF:0000058") Annotation( "PMID:23499937") "Any process that modulates the frequency, rate or extent of lysosomal protein catabolic process.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2016-04-26T12:10:01Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of cellular protein breakdown in lysosome") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of cellular protein catabolic process in lysosome") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of cellular protein catabolism in lysosome") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of cellular protein degradation in lysosome") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of lysosomal protein catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of lysosomal protein degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of lysosomal proteolysis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of proteolysis within lysosome") -AnnotationAssertion( "GO:1905165") -AnnotationAssertion(rdfs:label "regulation of lysosomal protein catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of lysosomal protein catabolic process) - -AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:TermGenie") Annotation( "GOC:bf") Annotation( "GO_REF:0000058") "Any process that stops, prevents or reduces the frequency, rate or extent of lysosomal protein catabolic process.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2016-04-26T12:10:10Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of cellular protein breakdown in lysosome") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of cellular protein catabolic process in lysosome") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of cellular protein catabolism in lysosome") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of cellular protein degradation in lysosome") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of lysosomal protein catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of lysosomal protein catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of lysosomal protein degradation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of cellular protein breakdown in lysosome") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of cellular protein catabolic process in lysosome") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of cellular protein catabolism in lysosome") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of cellular protein degradation in lysosome") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of lysosomal protein catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of lysosomal protein catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of lysosomal protein degradation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of cellular protein breakdown in lysosome") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of cellular protein catabolic process in lysosome") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of cellular protein catabolism in lysosome") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of cellular protein degradation in lysosome") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of lysosomal protein catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of lysosomal protein catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of lysosomal protein degradation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of cellular protein breakdown in lysosome") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of cellular protein catabolic process in lysosome") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of cellular protein catabolism in lysosome") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of cellular protein degradation in lysosome") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of lysosomal protein catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of lysosomal protein degradation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of cellular protein breakdown in lysosome") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of cellular protein catabolic process in lysosome") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of cellular protein catabolism in lysosome") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of cellular protein degradation in lysosome") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of lysosomal protein catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of lysosomal protein catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of lysosomal protein degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of lysosomal proteolysis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of proteolysis within lysosome") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of lysosomal proteolysis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of proteolysis within lysosome") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of lysosomal proteolysis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of proteolysis within lysosome") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of lysosomal proteolysis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of proteolysis within lysosome") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of lysosomal proteolysis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of proteolysis within lysosome") -AnnotationAssertion( "GO:1905166") -AnnotationAssertion(rdfs:label "negative regulation of lysosomal protein catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of lysosomal protein catabolic process) - -AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:TermGenie") Annotation( "GOC:bf") Annotation( "GO_REF:0000058") "Any process that activates or increases the frequency, rate or extent of lysosomal protein catabolic process.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2016-04-26T12:10:19Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of cellular protein breakdown in lysosome") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of cellular protein catabolic process in lysosome") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of cellular protein catabolism in lysosome") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of cellular protein degradation in lysosome") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of lysosomal protein catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of lysosomal protein degradation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of cellular protein breakdown in lysosome") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of cellular protein catabolic process in lysosome") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of cellular protein catabolism in lysosome") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of cellular protein degradation in lysosome") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of lysosomal protein catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of lysosomal protein catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of lysosomal protein degradation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of cellular protein breakdown in lysosome") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of cellular protein catabolic process in lysosome") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of cellular protein catabolism in lysosome") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of cellular protein degradation in lysosome") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of lysosomal protein catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of lysosomal protein catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of lysosomal protein degradation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of cellular protein breakdown in lysosome") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of cellular protein catabolic process in lysosome") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of cellular protein catabolism in lysosome") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of cellular protein degradation in lysosome") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of lysosomal protein catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of lysosomal protein catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of lysosomal protein degradation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of cellular protein breakdown in lysosome") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of cellular protein catabolic process in lysosome") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of cellular protein catabolism in lysosome") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of cellular protein degradation in lysosome") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of lysosomal protein catabolic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of lysosomal protein catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of lysosomal protein degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of lysosomal proteolysis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of proteolysis within lysosome") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of lysosomal proteolysis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of proteolysis within lysosome") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of lysosomal proteolysis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of proteolysis within lysosome") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of lysosomal proteolysis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of proteolysis within lysosome") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of lysosomal proteolysis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of proteolysis within lysosome") -AnnotationAssertion( "GO:1905167") -AnnotationAssertion(rdfs:label "positive regulation of lysosomal protein catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of cardiocyte differentiation) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_miRNA") Annotation( "GOC:TermGenie") Annotation( "GOC:bc") Annotation( "GO_REF:0000058") Annotation( "PMID:23069713") "Any process that modulates the frequency, rate or extent of cardiocyte differentiation.") -AnnotationAssertion( "bc") -AnnotationAssertion( "2016-06-02T07:20:01Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of cardiac cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of heart cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905207") -AnnotationAssertion(rdfs:label "regulation of cardiocyte differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of cardiocyte differentiation) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_miRNA") Annotation( "GOC:TermGenie") Annotation( "GOC:bc") Annotation( "GO_REF:0000058") Annotation( "PMID:23069713") "Any process that stops, prevents or reduces the frequency, rate or extent of cardiocyte differentiation.") -AnnotationAssertion( "bc") -AnnotationAssertion( "2016-06-02T07:20:09Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of cardiac cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of cardiocyte differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of heart cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of cardiac cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of cardiocyte differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of heart cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of cardiac cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of cardiocyte differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of heart cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of cardiac cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of heart cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of cardiac cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of cardiocyte differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of heart cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905208") -AnnotationAssertion(rdfs:label "negative regulation of cardiocyte differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of cardiocyte differentiation) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_miRNA") Annotation( "GOC:TermGenie") Annotation( "GOC:bc") Annotation( "GO_REF:0000058") Annotation( "PMID:23069713") "Any process that activates or increases the frequency, rate or extent of cardiocyte differentiation.") -AnnotationAssertion( "bc") -AnnotationAssertion( "2016-06-02T07:20:16Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of cardiac cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of heart cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of cardiac cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of cardiocyte differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of heart cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of cardiac cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of cardiocyte differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of heart cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of cardiac cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of cardiocyte differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of heart cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of cardiac cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of cardiocyte differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of heart cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905209") -AnnotationAssertion(rdfs:label "positive regulation of cardiocyte differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (negative regulation of mitotic chromosome condensation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:23219725") "Any process that stops, prevents or reduces the frequency, rate or extent of mitotic chromosome condensation.") -AnnotationAssertion( "vw") -AnnotationAssertion( "2016-06-03T08:41:08Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905213") -AnnotationAssertion(rdfs:label "negative regulation of mitotic chromosome condensation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of RNA binding) - -AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:TermGenie") Annotation( "GOC:bf") Annotation( "GO_REF:0000059") "Any process that modulates the frequency, rate or extent of RNA binding.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2016-06-06T10:20:56Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905214") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "regulation of RNA binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of RNA binding) - -AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:TermGenie") Annotation( "GOC:bf") Annotation( "GO_REF:0000059") "Any process that stops, prevents or reduces the frequency, rate or extent of RNA binding.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2016-06-06T10:21:04Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of RNA binding") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of RNA binding") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of RNA binding") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of RNA binding") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905215") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "negative regulation of RNA binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of RNA binding) - -AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:TermGenie") Annotation( "GOC:bf") Annotation( "GO_REF:0000059") Annotation( "PMID:25116364") "Any process that activates or increases the frequency, rate or extent of RNA binding.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2016-06-06T10:21:12Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of RNA binding") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of RNA binding") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of RNA binding") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of RNA binding") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905216") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "positive regulation of RNA binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of platelet formation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:10606160") "Any process that modulates the frequency, rate or extent of platelet formation.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2016-06-06T22:15:46Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of platelet extrusion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905219") -AnnotationAssertion(rdfs:label "regulation of platelet formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (negative regulation of platelet formation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:10606160") "Any process that stops, prevents or reduces the frequency, rate or extent of platelet formation.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2016-06-06T22:15:54Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of platelet extrusion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of platelet formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of platelet extrusion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of platelet formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of platelet extrusion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of platelet formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of platelet extrusion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of platelet extrusion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of platelet formation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905220") -AnnotationAssertion(rdfs:label "negative regulation of platelet formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of platelet formation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:10606160") "Any process that activates or increases the frequency, rate or extent of platelet formation.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2016-06-06T22:16:02Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of platelet extrusion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of platelet extrusion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of platelet formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of platelet extrusion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of platelet formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of platelet extrusion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of platelet formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of platelet extrusion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of platelet formation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905221") -AnnotationAssertion(rdfs:label "positive regulation of platelet formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (atrioventricular canal morphogenesis) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "GO_REF:0000083") Annotation( "PMID:19703439") "The developmental process by which an atrioventricular canal is generated and organized.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2016-06-07T09:09:51Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "AV canal morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "AVC morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "atrial canal morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "atrio-ventricular canal morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "canalis atrioventricularis morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "ependymal canal morphogenesis") -AnnotationAssertion( "GO:1905222") -AnnotationAssertion(rdfs:label "atrioventricular canal morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (epicardium morphogenesis) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "GO_REF:0000083") Annotation( "PMID:18718461") "The developmental process by which an epicardium is generated and organized.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2016-06-07T10:02:32Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "heart epicardium morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "visceral serous pericardium of heart morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "visceral serous pericardium proper morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "pericardium visceral mesothelium morphogenesis") -AnnotationAssertion( "GO:1905223") -AnnotationAssertion(rdfs:label "epicardium morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cellular response to L-glutamate) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000071") Annotation( "PMID:25962137") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-glutamate(1-) stimulus.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2016-06-07T17:30:08Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "cellular response to L-glutamate(1-)") -AnnotationAssertion( "GO:1905232") -AnnotationAssertion(rdfs:label "cellular response to L-glutamate") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of chromatin organization) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:pr") Annotation( "GOC:vw") Annotation( "GO_REF:0000058") Annotation( "PMID:654321") "Any process that stops, prevents or reduces the frequency, rate or extent of chromatin organization.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/22766"^^xsd:anyURI) -AnnotationAssertion( "pr") -AnnotationAssertion( "2016-06-15T20:14:47Z") -AnnotationAssertion( "GO:0045798") -AnnotationAssertion( "GO:1903309") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of chromatin organisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of chromatin organization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of establishment or maintenance of chromatin architecture") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of chromatin organisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of chromatin organization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of establishment or maintenance of chromatin architecture") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of chromatin organisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of chromatin organization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of establishment or maintenance of chromatin architecture") -AnnotationAssertion( "negative regulation of chromatin assembly/disassembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of chromatin organisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of establishment or maintenance of chromatin architecture") -AnnotationAssertion( "inhibition of chromatin assembly or disassembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of chromatin organisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of chromatin organization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of establishment or maintenance of chromatin architecture") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "down regulation of chromatin assembly or disassembly") -AnnotationAssertion( "down-regulation of chromatin assembly or disassembly") -AnnotationAssertion( "downregulation of chromatin assembly or disassembly") -AnnotationAssertion( "negative regulation of chromatin assembly or disassembly") -AnnotationAssertion( "negative regulation of chromatin modification") -AnnotationAssertion( "GO:1905268") -AnnotationAssertion(rdfs:label "negative regulation of chromatin organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of chromatin organization) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:pr") Annotation( "GOC:vw") Annotation( "GO_REF:0000058") Annotation( "PMID:654321") "Any process that activates or increases the frequency, rate or extent of chromatin organization.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/22766"^^xsd:anyURI) -AnnotationAssertion( "pr") -AnnotationAssertion( "2016-06-15T20:14:56Z") -AnnotationAssertion( "GO:0045799") -AnnotationAssertion( "GO:1903310") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of chromatin organisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of establishment or maintenance of chromatin architecture") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of chromatin organisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of chromatin organization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of establishment or maintenance of chromatin architecture") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of chromatin organisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of chromatin organization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of establishment or maintenance of chromatin architecture") -AnnotationAssertion( "upregulation of chromatin assembly or disassembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of chromatin organisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of chromatin organization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of establishment or maintenance of chromatin architecture") -AnnotationAssertion( "activation of chromatin assembly or disassembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of chromatin organisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of chromatin organization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of establishment or maintenance of chromatin architecture") -AnnotationAssertion( "stimulation of chromatin assembly or disassembly") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "positive regulation of chromatin assembly or disassembly") -AnnotationAssertion( "positive regulation of chromatin assembly/disassembly") -AnnotationAssertion( "positive regulation of chromatin modification") -AnnotationAssertion( "up regulation of chromatin assembly or disassembly") -AnnotationAssertion( "up-regulation of chromatin assembly or disassembly") -AnnotationAssertion( "GO:1905269") -AnnotationAssertion(rdfs:label "positive regulation of chromatin organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (regulation of epithelial tube formation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:bhm") Annotation( "GO_REF:0000058") Annotation( "PMID:25745997") "Any process that modulates the frequency, rate or extent of epithelial tube formation.") -AnnotationAssertion( "bhm") -AnnotationAssertion( "2016-06-20T09:35:41Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905276") -AnnotationAssertion(rdfs:comment "An example of this is MMRN2 in human (Q9H8L6) in PMID:25745997 (inferred from direct assay).") -AnnotationAssertion(rdfs:label "regulation of epithelial tube formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of epithelial tube formation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:bhm") Annotation( "GO_REF:0000058") Annotation( "PMID:25745997") "Any process that stops, prevents or reduces the frequency, rate or extent of epithelial tube formation.") -AnnotationAssertion( "bhm") -AnnotationAssertion( "2016-06-20T09:35:49Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of epithelial tube formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of epithelial tube formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of epithelial tube formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of epithelial tube formation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905277") -AnnotationAssertion(rdfs:comment "An example of this is MMRN2 in human (Q9H8L6) in PMID:25745997 (inferred from direct assay).") -AnnotationAssertion(rdfs:label "negative regulation of epithelial tube formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of epithelial tube formation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:bhm") Annotation( "GO_REF:0000058") Annotation( "PMID:25745997") "Any process that activates or increases the frequency, rate or extent of epithelial tube formation.") -AnnotationAssertion( "bhm") -AnnotationAssertion( "2016-06-20T09:35:57Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of epithelial tube formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of epithelial tube formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of epithelial tube formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of epithelial tube formation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905278") -AnnotationAssertion(rdfs:comment "An example of this is MMRN2 in human (Q9H8L6) in PMID:25745997 (inferred from direct assay).") -AnnotationAssertion(rdfs:label "positive regulation of epithelial tube formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (fibrous ring of heart morphogenesis) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "GO_REF:0000083") Annotation( "PMID:16037571") "The developmental process by which a fibrous ring of heart is generated and organized.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2016-06-21T09:46:54Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "anulus fibrosus of heart morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "Lower's ring morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "annulus fibrosus cordis morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "anulus fibrosus cordis morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "aortic annulus morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "atrioventricular ring morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "coronary tendon morphogenesis") -AnnotationAssertion( "GO:1905285") -AnnotationAssertion(rdfs:label "fibrous ring of heart morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (vascular associated smooth muscle cell apoptotic process) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_miRNA") Annotation( "GOC:TermGenie") Annotation( "GOC:rph") Annotation( "GO_REF:0000085") Annotation( "PMID:26493107") "Any apoptotic process in a vascular associated smooth muscle cell.") -AnnotationAssertion( "rph") -AnnotationAssertion( "2016-06-23T13:24:20Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "VSMC apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "vascular smooth muscle cell apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "VSMC apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "vascular associated smooth muscle cell apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "vascular smooth muscle cell apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905288") -AnnotationAssertion(rdfs:label "vascular associated smooth muscle cell apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of neural crest cell differentiation) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "GO_REF:0000058") Annotation( "PMID:15073157") "Any process that modulates the frequency, rate or extent of neural crest cell differentiation.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2016-06-28T15:02:01Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905292") -AnnotationAssertion(rdfs:label "regulation of neural crest cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of neural crest cell differentiation) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "GO_REF:0000058") Annotation( "PMID:15073157") "Any process that stops, prevents or reduces the frequency, rate or extent of neural crest cell differentiation.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2016-06-28T15:02:09Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of neural crest cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of neural crest cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of neural crest cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of neural crest cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905293") -AnnotationAssertion(rdfs:label "negative regulation of neural crest cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of neural crest cell differentiation) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "GO_REF:0000058") Annotation( "PMID:15073157") "Any process that activates or increases the frequency, rate or extent of neural crest cell differentiation.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2016-06-28T15:02:16Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of neural crest cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of neural crest cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of neural crest cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of neural crest cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905294") -AnnotationAssertion(rdfs:label "positive regulation of neural crest cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (regulation of intestinal epithelial cell development) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_miRNA") Annotation( "GOC:TermGenie") Annotation( "GOC:rph") Annotation( "GO_REF:0000058") Annotation( "PMID:23904268") "Any process that modulates the frequency, rate or extent of intestinal epithelial cell development.") -AnnotationAssertion( "rph") -AnnotationAssertion( "2016-06-30T11:40:47Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905298") -AnnotationAssertion(rdfs:label "regulation of intestinal epithelial cell development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (negative regulation of intestinal epithelial cell development) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_miRNA") Annotation( "GOC:TermGenie") Annotation( "GOC:rph") Annotation( "GO_REF:0000058") Annotation( "PMID:23904268") "Any process that stops, prevents or reduces the frequency, rate or extent of intestinal epithelial cell development.") -AnnotationAssertion( "rph") -AnnotationAssertion( "2016-06-30T11:40:55Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of intestinal epithelial cell development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of intestinal epithelial cell development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of intestinal epithelial cell development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of intestinal epithelial cell development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905299") -AnnotationAssertion(rdfs:label "negative regulation of intestinal epithelial cell development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of intestinal epithelial cell development) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_miRNA") Annotation( "GOC:TermGenie") Annotation( "GOC:rph") Annotation( "GO_REF:0000058") Annotation( "PMID:23904268") "Any process that activates or increases the frequency, rate or extent of intestinal epithelial cell development.") -AnnotationAssertion( "rph") -AnnotationAssertion( "2016-06-30T11:41:02Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of intestinal epithelial cell development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of intestinal epithelial cell development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of intestinal epithelial cell development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of intestinal epithelial cell development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905300") -AnnotationAssertion(rdfs:label "positive regulation of intestinal epithelial cell development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (regulation of cardiac myofibril assembly) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "GO_REF:0000058") Annotation( "PMID:16151019") "Any process that modulates the frequency, rate or extent of cardiac myofibril assembly.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2016-07-06T10:01:49Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of cardiac myofibril development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of cardiac myofibril morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of heart myofibril assembly") -AnnotationAssertion( "GO:1905304") -AnnotationAssertion(rdfs:label "regulation of cardiac myofibril assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (negative regulation of cardiac myofibril assembly) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "GO_REF:0000058") Annotation( "PMID:16151019") "Any process that stops, prevents or reduces the frequency, rate or extent of cardiac myofibril assembly.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2016-07-06T10:01:58Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of cardiac myofibril assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of cardiac myofibril development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of cardiac myofibril morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of cardiac myofibril assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of cardiac myofibril development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of cardiac myofibril morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of cardiac myofibril assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of cardiac myofibril development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of cardiac myofibril morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of cardiac myofibril development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of cardiac myofibril morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of cardiac myofibril assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of cardiac myofibril development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of cardiac myofibril morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of heart myofibril assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of heart myofibril assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of heart myofibril assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of heart myofibril assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of heart myofibril assembly") -AnnotationAssertion( "GO:1905305") -AnnotationAssertion(rdfs:label "negative regulation of cardiac myofibril assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of cardiac myofibril assembly) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "GO_REF:0000058") Annotation( "PMID:16151019") "Any process that activates or increases the frequency, rate or extent of cardiac myofibril assembly.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2016-07-06T10:02:07Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of cardiac myofibril development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of cardiac myofibril morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of cardiac myofibril assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of cardiac myofibril development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of cardiac myofibril morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of cardiac myofibril assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of cardiac myofibril development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of cardiac myofibril morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of cardiac myofibril assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of cardiac myofibril development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of cardiac myofibril morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of cardiac myofibril assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of cardiac myofibril development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of cardiac myofibril morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of heart myofibril assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of heart myofibril assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of heart myofibril assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of heart myofibril assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of heart myofibril assembly") -AnnotationAssertion( "GO:1905306") -AnnotationAssertion(rdfs:label "positive regulation of cardiac myofibril assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "GO_REF:0000058") Annotation( "PMID:17628518") "Any process that modulates the frequency, rate or extent of cardiac neural crest cell migration involved in outflow tract morphogenesis.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2016-07-11T17:34:26Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905310") -AnnotationAssertion(rdfs:label "regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "GO_REF:0000058") Annotation( "PMID:17628518") "Any process that stops, prevents or reduces the frequency, rate or extent of cardiac neural crest cell migration involved in outflow tract morphogenesis.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2016-07-11T17:34:35Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of cardiac neural crest cell migration involved in outflow tract morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of cardiac neural crest cell migration involved in outflow tract morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905311") -AnnotationAssertion(rdfs:label "negative regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "GO_REF:0000058") Annotation( "PMID:17628518") "Any process that activates or increases the frequency, rate or extent of cardiac neural crest cell migration involved in outflow tract morphogenesis.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2016-07-11T17:34:43Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of cardiac neural crest cell migration involved in outflow tract morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of cardiac neural crest cell migration involved in outflow tract morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905312") -AnnotationAssertion(rdfs:label "positive regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (semi-lunar valve development) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "GO_REF:0000094") Annotation( "PMID:19409885") "The process whose specific outcome is the progression of a semi-lunar valve over time, from its formation to the mature structure.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2016-07-11T17:50:44Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "semilunar valve development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "semilunar valves development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905314") -AnnotationAssertion(rdfs:label "semi-lunar valve development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cell proliferation involved in endocardial cushion morphogenesis) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "GO_REF:0000060") Annotation( "PMID:20652948") "Any cell proliferation that is involved in endocardial cushion morphogenesis.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2016-07-12T13:56:36Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905315") -AnnotationAssertion(rdfs:label "cell proliferation involved in endocardial cushion morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (superior endocardial cushion morphogenesis) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "GO_REF:0000083") Annotation( "PMID:17050629") "The developmental process by which a superior endocardial cushion is generated and organized.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2016-07-12T14:08:35Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "dorsal endocardial cushion morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905316") -AnnotationAssertion(rdfs:label "superior endocardial cushion morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (inferior endocardial cushion morphogenesis) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "GO_REF:0000083") Annotation( "PMID:17050629") "The developmental process by which an inferior endocardial cushion is generated and organized.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2016-07-12T14:14:56Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "ventral endocardial cushion morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905317") -AnnotationAssertion(rdfs:label "inferior endocardial cushion morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (mesenchymal stem cell migration) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000091") Annotation( "PMID:24924806") Annotation( "PMID:25181476") "The orderly movement of a mesenchymal stem cell from one site to another.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2016-07-14T17:13:02Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905319") -AnnotationAssertion(rdfs:label "mesenchymal stem cell migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of mesenchymal stem cell migration) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:26846297") "Any process that modulates the frequency, rate or extent of mesenchymal stem cell migration.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2016-07-15T22:19:14Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905320") -AnnotationAssertion(rdfs:label "regulation of mesenchymal stem cell migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of mesenchymal stem cell migration) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:26846297") "Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal stem cell migration.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2016-07-15T22:19:22Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of mesenchymal stem cell migration") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of mesenchymal stem cell migration") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of mesenchymal stem cell migration") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of mesenchymal stem cell migration") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905321") -AnnotationAssertion(rdfs:label "negative regulation of mesenchymal stem cell migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of mesenchymal stem cell migration) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:26846297") "Any process that activates or increases the frequency, rate or extent of mesenchymal stem cell migration.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2016-07-15T22:19:29Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of mesenchymal stem cell migration") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of mesenchymal stem cell migration") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of mesenchymal stem cell migration") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of mesenchymal stem cell migration") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905322") -AnnotationAssertion(rdfs:label "positive regulation of mesenchymal stem cell migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (tracheoesophageal septum formation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000081") Annotation( "PMID:9731532") "The process that gives rise to the tracheoesophageal septum. This process pertains to the initial formation of a structure from unspecified parts.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2016-07-21T18:18:57Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "esophagotracheal septum formation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "tracheoesophageal ridges formation") -AnnotationAssertion( "GO:1905327") -AnnotationAssertion(rdfs:label "tracheoesophageal septum formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of morphogenesis of an epithelium) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:bhm") Annotation( "GO_REF:0000058") Annotation( "PMID:25745997") "Any process that modulates the frequency, rate or extent of morphogenesis of an epithelium.") -AnnotationAssertion( "bhm") -AnnotationAssertion( "2016-07-22T07:13:49Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of epithelium morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905330") -AnnotationAssertion(rdfs:comment "An example of this is MMRN2 in human (Q9H8L6) in PMID:25745997 (inferred from direct assay).") -AnnotationAssertion(rdfs:label "regulation of morphogenesis of an epithelium") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (negative regulation of morphogenesis of an epithelium) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:bhm") Annotation( "GO_REF:0000058") Annotation( "PMID:25745997") "Any process that stops, prevents or reduces the frequency, rate or extent of morphogenesis of an epithelium.") -AnnotationAssertion( "bhm") -AnnotationAssertion( "2016-07-22T07:13:57Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of epithelium morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of morphogenesis of an epithelium") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of epithelium morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of morphogenesis of an epithelium") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of epithelium morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of morphogenesis of an epithelium") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of epithelium morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of epithelium morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of morphogenesis of an epithelium") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905331") -AnnotationAssertion(rdfs:comment "An example of this is MMRN2 in human (Q9H8L6) in PMID:25745997 (inferred from direct assay).") -AnnotationAssertion(rdfs:label "negative regulation of morphogenesis of an epithelium") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of morphogenesis of an epithelium) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:bhm") Annotation( "GO_REF:0000058") Annotation( "PMID:25745997") "Any process that activates or increases the frequency, rate or extent of morphogenesis of an epithelium.") -AnnotationAssertion( "bhm") -AnnotationAssertion( "2016-07-22T07:14:05Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of epithelium morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of epithelium morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of morphogenesis of an epithelium") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of epithelium morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of morphogenesis of an epithelium") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of epithelium morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of morphogenesis of an epithelium") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of epithelium morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of morphogenesis of an epithelium") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905332") -AnnotationAssertion(rdfs:comment "An example of this is MMRN2 in human (Q9H8L6) in PMID:25745997 (inferred from direct assay).") -AnnotationAssertion(rdfs:label "positive regulation of morphogenesis of an epithelium") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (ciliary transition zone assembly) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:cilia") Annotation( "GO_REF:0000079") Annotation( "PMID:21725307") Annotation( "PMID:23644468") Annotation( "PMID:24448408") Annotation( "PMID:26595381") Annotation( "PMID:26982032") "The aggregation, arrangement and bonding together of a set of components to form a ciliary transition zone.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2016-08-04T14:49:43Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "cilial transition zone assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "cilial transition zone formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "ciliary transition zone formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "cilium transition zone assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "cilium transition zone formation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905349") -AnnotationAssertion(rdfs:label "ciliary transition zone assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (pericyte cell migration) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_miRNA") Annotation( "GOC:TermGenie") Annotation( "GOC:rph") Annotation( "GO_REF:0000091") Annotation( "PMID:26268439") "The orderly movement of a pericyte cell from one site to another.") -AnnotationAssertion( "rph") -AnnotationAssertion( "2016-08-05T12:01:48Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905351") -AnnotationAssertion(rdfs:label "pericyte cell migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (protein localization to presynapse) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000087") Annotation( "PMID:24449494") "A process in which a protein is transported to, or maintained in, a location within a presynapse.") -AnnotationAssertion( "dos") -AnnotationAssertion( "2016-08-18T14:42:59Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "protein localisation in presynapse") -AnnotationAssertion(Annotation( "GOC:TermGenie") "protein localisation to presynapse") -AnnotationAssertion(Annotation( "GOC:TermGenie") "protein localization in presynapse") -AnnotationAssertion(Annotation( "PMID:24449494") "recruitment of presynaptic proteins") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905383") -AnnotationAssertion(rdfs:label "protein localization to presynapse") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of protein localization to presynapse) - -AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:TermGenie") Annotation( "GOC:bf") Annotation( "GO_REF:0000058") Annotation( "PMID:24449494") "Any process that modulates the frequency, rate or extent of protein localization to presynapse.") -AnnotationAssertion( "dos") -AnnotationAssertion( "2016-08-18T14:56:00Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of protein localisation in presynapse") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of protein localisation to presynapse") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of protein localization in presynapse") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of recruitment of presynaptic proteins") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905384") -AnnotationAssertion(rdfs:label "regulation of protein localization to presynapse") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of protein localization to presynapse) - -AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:TermGenie") Annotation( "GOC:bf") Annotation( "GO_REF:0000058") Annotation( "PMID:24449494") "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to presynapse.") -AnnotationAssertion( "dos") -AnnotationAssertion( "2016-08-18T14:56:08Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of protein localisation in presynapse") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of protein localisation to presynapse") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of protein localization in presynapse") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of protein localization to presynapse") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of recruitment of presynaptic proteins") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of protein localisation in presynapse") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of protein localisation to presynapse") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of protein localization in presynapse") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of protein localization to presynapse") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of recruitment of presynaptic proteins") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of protein localisation in presynapse") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of protein localisation to presynapse") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of protein localization in presynapse") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of protein localization to presynapse") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of recruitment of presynaptic proteins") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of protein localisation in presynapse") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of protein localisation to presynapse") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of protein localization in presynapse") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of recruitment of presynaptic proteins") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of protein localisation in presynapse") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of protein localisation to presynapse") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of protein localization in presynapse") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of protein localization to presynapse") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of recruitment of presynaptic proteins") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905385") -AnnotationAssertion(rdfs:label "negative regulation of protein localization to presynapse") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of protein localization to presynapse) - -AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:TermGenie") Annotation( "GOC:bf") Annotation( "GO_REF:0000058") Annotation( "PMID:24449494") "Any process that activates or increases the frequency, rate or extent of protein localization to presynapse.") -AnnotationAssertion( "dos") -AnnotationAssertion( "2016-08-18T14:56:21Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of protein localisation in presynapse") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of protein localisation to presynapse") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of protein localization in presynapse") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of recruitment of presynaptic proteins") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of protein localisation in presynapse") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of protein localisation to presynapse") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of protein localization in presynapse") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of protein localization to presynapse") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of recruitment of presynaptic proteins") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of protein localisation in presynapse") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of protein localisation to presynapse") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of protein localization in presynapse") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of protein localization to presynapse") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of recruitment of presynaptic proteins") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of protein localisation in presynapse") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of protein localisation to presynapse") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of protein localization in presynapse") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of protein localization to presynapse") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of recruitment of presynaptic proteins") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of protein localisation in presynapse") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of protein localisation to presynapse") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of protein localization in presynapse") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of protein localization to presynapse") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of recruitment of presynaptic proteins") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905386") -AnnotationAssertion(rdfs:label "positive regulation of protein localization to presynapse") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (response to beta-carotene) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000071") Annotation( "PMID:16771696") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a beta-carotene stimulus.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2016-08-18T16:18:24Z") -AnnotationAssertion( "response to beta,beta-carotene") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905387") -AnnotationAssertion(rdfs:label "response to beta-carotene") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cellular response to beta-carotene) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000071") Annotation( "PMID:16771696") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a beta-carotene stimulus.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2016-08-18T16:18:31Z") -AnnotationAssertion( "cellular response to beta,beta-carotene") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905388") -AnnotationAssertion(rdfs:label "cellular response to beta-carotene") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (intracellular signal transduction involved in positive regulation of cell growth) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:al") Annotation( "GOC:vw") Annotation( "GO_REF:0000060") Annotation( "PMID:15917811") "Any intracellular signal transduction that is involved in positive regulation of cell growth.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2016-09-07T18:15:01Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "intracellular signal transduction involved in up regulation of cell growth") -AnnotationAssertion(Annotation( "GOC:TermGenie") "intracellular signal transduction involved in up-regulation of cell growth") -AnnotationAssertion(Annotation( "GOC:TermGenie") "intracellular signal transduction involved in upregulation of cell growth") -AnnotationAssertion(Annotation( "GOC:TermGenie") "intracellular signaling chain involved in positive regulation of cell growth") -AnnotationAssertion(Annotation( "GOC:TermGenie") "intracellular signaling chain involved in up regulation of cell growth") -AnnotationAssertion(Annotation( "GOC:TermGenie") "intracellular signaling chain involved in up-regulation of cell growth") -AnnotationAssertion(Annotation( "GOC:TermGenie") "intracellular signaling chain involved in upregulation of cell growth") -AnnotationAssertion(Annotation( "GOC:TermGenie") "intracellular protein kinase cascade involved in activation of cell growth") -AnnotationAssertion(Annotation( "GOC:TermGenie") "intracellular protein kinase cascade involved in positive regulation of cell growth") -AnnotationAssertion(Annotation( "GOC:TermGenie") "intracellular protein kinase cascade involved in stimulation of cell growth") -AnnotationAssertion(Annotation( "GOC:TermGenie") "intracellular protein kinase cascade involved in up regulation of cell growth") -AnnotationAssertion(Annotation( "GOC:TermGenie") "intracellular protein kinase cascade involved in up-regulation of cell growth") -AnnotationAssertion(Annotation( "GOC:TermGenie") "intracellular protein kinase cascade involved in upregulation of cell growth") -AnnotationAssertion(Annotation( "GOC:TermGenie") "intracellular signal transduction involved in activation of cell growth") -AnnotationAssertion(Annotation( "GOC:TermGenie") "intracellular signal transduction involved in stimulation of cell growth") -AnnotationAssertion(Annotation( "GOC:TermGenie") "intracellular signal transduction pathway involved in activation of cell growth") -AnnotationAssertion(Annotation( "GOC:TermGenie") "intracellular signal transduction pathway involved in positive regulation of cell growth") -AnnotationAssertion(Annotation( "GOC:TermGenie") "intracellular signal transduction pathway involved in stimulation of cell growth") -AnnotationAssertion(Annotation( "GOC:TermGenie") "intracellular signal transduction pathway involved in up regulation of cell growth") -AnnotationAssertion(Annotation( "GOC:TermGenie") "intracellular signal transduction pathway involved in up-regulation of cell growth") -AnnotationAssertion(Annotation( "GOC:TermGenie") "intracellular signal transduction pathway involved in upregulation of cell growth") -AnnotationAssertion(Annotation( "GOC:TermGenie") "intracellular signaling chain involved in activation of cell growth") -AnnotationAssertion(Annotation( "GOC:TermGenie") "intracellular signaling chain involved in stimulation of cell growth") -AnnotationAssertion(Annotation( "GOC:TermGenie") "protein kinase cascade involved in activation of cell growth") -AnnotationAssertion(Annotation( "GOC:TermGenie") "protein kinase cascade involved in positive regulation of cell growth") -AnnotationAssertion(Annotation( "GOC:TermGenie") "protein kinase cascade involved in stimulation of cell growth") -AnnotationAssertion(Annotation( "GOC:TermGenie") "protein kinase cascade involved in up regulation of cell growth") -AnnotationAssertion(Annotation( "GOC:TermGenie") "protein kinase cascade involved in up-regulation of cell growth") -AnnotationAssertion(Annotation( "GOC:TermGenie") "protein kinase cascade involved in upregulation of cell growth") -AnnotationAssertion(Annotation( "GOC:TermGenie") "signal transmission via intracellular cascade involved in activation of cell growth") -AnnotationAssertion(Annotation( "GOC:TermGenie") "signal transmission via intracellular cascade involved in positive regulation of cell growth") -AnnotationAssertion(Annotation( "GOC:TermGenie") "signal transmission via intracellular cascade involved in stimulation of cell growth") -AnnotationAssertion(Annotation( "GOC:TermGenie") "signal transmission via intracellular cascade involved in up regulation of cell growth") -AnnotationAssertion(Annotation( "GOC:TermGenie") "signal transmission via intracellular cascade involved in up-regulation of cell growth") -AnnotationAssertion(Annotation( "GOC:TermGenie") "signal transmission via intracellular cascade involved in upregulation of cell growth") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "intracellular signaling cascade involved in activation of cell growth") -AnnotationAssertion(Annotation( "GOC:TermGenie") "intracellular signaling cascade involved in positive regulation of cell growth") -AnnotationAssertion(Annotation( "GOC:TermGenie") "intracellular signaling cascade involved in stimulation of cell growth") -AnnotationAssertion(Annotation( "GOC:TermGenie") "intracellular signaling cascade involved in up regulation of cell growth") -AnnotationAssertion(Annotation( "GOC:TermGenie") "intracellular signaling cascade involved in up-regulation of cell growth") -AnnotationAssertion(Annotation( "GOC:TermGenie") "intracellular signaling cascade involved in upregulation of cell growth") -AnnotationAssertion(Annotation( "GOC:TermGenie") "intracellular signaling pathway involved in activation of cell growth") -AnnotationAssertion(Annotation( "GOC:TermGenie") "intracellular signaling pathway involved in positive regulation of cell growth") -AnnotationAssertion(Annotation( "GOC:TermGenie") "intracellular signaling pathway involved in stimulation of cell growth") -AnnotationAssertion(Annotation( "GOC:TermGenie") "intracellular signaling pathway involved in up regulation of cell growth") -AnnotationAssertion(Annotation( "GOC:TermGenie") "intracellular signaling pathway involved in up-regulation of cell growth") -AnnotationAssertion(Annotation( "GOC:TermGenie") "intracellular signaling pathway involved in upregulation of cell growth") -AnnotationAssertion(Annotation( "GOC:TermGenie") "signal transduction via intracellular signaling cascade involved in activation of cell growth") -AnnotationAssertion(Annotation( "GOC:TermGenie") "signal transduction via intracellular signaling cascade involved in positive regulation of cell growth") -AnnotationAssertion(Annotation( "GOC:TermGenie") "signal transduction via intracellular signaling cascade involved in stimulation of cell growth") -AnnotationAssertion(Annotation( "GOC:TermGenie") "signal transduction via intracellular signaling cascade involved in up regulation of cell growth") -AnnotationAssertion(Annotation( "GOC:TermGenie") "signal transduction via intracellular signaling cascade involved in up-regulation of cell growth") -AnnotationAssertion(Annotation( "GOC:TermGenie") "signal transduction via intracellular signaling cascade involved in upregulation of cell growth") -AnnotationAssertion( "GO:1905427") -AnnotationAssertion(rdfs:label "intracellular signal transduction involved in positive regulation of cell growth") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of retrograde trans-synaptic signaling by neuropeptide) - -AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:TermGenie") Annotation( "GOC:bf") Annotation( "GO_REF:0000058") Annotation( "PMID:19448629") "Any process that modulates the frequency, rate or extent of retrograde trans-synaptic signaling by neuropeptide.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2016-09-14T10:56:47Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:bf") "regulation of neuropeptide-mediated retrograde trans-synaptic signaling") -AnnotationAssertion( "GO:1905432") -AnnotationAssertion(rdfs:label "regulation of retrograde trans-synaptic signaling by neuropeptide") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of retrograde trans-synaptic signaling by neuropeptide) - -AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:TermGenie") Annotation( "GOC:bf") Annotation( "GO_REF:0000058") Annotation( "PMID:19448629") "Any process that stops, prevents or reduces the frequency, rate or extent of retrograde trans-synaptic signaling by neuropeptide.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2016-09-14T10:56:55Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of retrograde trans-synaptic signaling by neuropeptide") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of retrograde trans-synaptic signaling by neuropeptide") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of retrograde trans-synaptic signaling by neuropeptide") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of retrograde trans-synaptic signaling by neuropeptide") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:bf") "inhibition of neuropeptide-mediated retrograde trans-synaptic signaling") -AnnotationAssertion(Annotation( "GOC:bf") "negative regulation of neuropeptide-mediated retrograde trans-synaptic signaling") -AnnotationAssertion( "GO:1905433") -AnnotationAssertion(rdfs:label "negative regulation of retrograde trans-synaptic signaling by neuropeptide") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of retrograde trans-synaptic signaling by neuropeptide) - -AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:TermGenie") Annotation( "GOC:bf") Annotation( "GO_REF:0000058") Annotation( "PMID:19448629") "Any process that activates or increases the frequency, rate or extent of retrograde trans-synaptic signaling by neuropeptide.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2016-09-14T10:57:02Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of retrograde trans-synaptic signaling by neuropeptide") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of retrograde trans-synaptic signaling by neuropeptide") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of retrograde trans-synaptic signaling by neuropeptide") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of retrograde trans-synaptic signaling by neuropeptide") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:bf") "positive regulation of neuropeptide-mediated retrograde trans-synaptic signaling") -AnnotationAssertion( "GO:1905434") -AnnotationAssertion(rdfs:label "positive regulation of retrograde trans-synaptic signaling by neuropeptide") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of myeloid progenitor cell differentiation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:27010503") "Any process that modulates the frequency, rate or extent of myeloid progenitor cell differentiation.") -AnnotationAssertion( "rz") -AnnotationAssertion( "2016-09-16T12:32:18Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905453") -AnnotationAssertion(rdfs:label "regulation of myeloid progenitor cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of myeloid progenitor cell differentiation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:27010503") "Any process that stops, prevents or reduces the frequency, rate or extent of myeloid progenitor cell differentiation.") -AnnotationAssertion( "rz") -AnnotationAssertion( "2016-09-16T12:32:26Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of myeloid progenitor cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of myeloid progenitor cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of myeloid progenitor cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of myeloid progenitor cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905454") -AnnotationAssertion(rdfs:label "negative regulation of myeloid progenitor cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of myeloid progenitor cell differentiation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:27010503") "Any process that activates or increases the frequency, rate or extent of myeloid progenitor cell differentiation.") -AnnotationAssertion( "rz") -AnnotationAssertion( "2016-09-16T12:32:33Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of myeloid progenitor cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of myeloid progenitor cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of myeloid progenitor cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of myeloid progenitor cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905455") -AnnotationAssertion(rdfs:label "positive regulation of myeloid progenitor cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of lymphoid progenitor cell differentiation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:27010503") "Any process that modulates the frequency, rate or extent of lymphoid progenitor cell differentiation.") -AnnotationAssertion( "rz") -AnnotationAssertion( "2016-09-16T12:32:40Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905456") -AnnotationAssertion(rdfs:label "regulation of lymphoid progenitor cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of lymphoid progenitor cell differentiation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:27010503") "Any process that stops, prevents or reduces the frequency, rate or extent of lymphoid progenitor cell differentiation.") -AnnotationAssertion( "rz") -AnnotationAssertion( "2016-09-16T12:32:48Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of lymphoid progenitor cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of lymphoid progenitor cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of lymphoid progenitor cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of lymphoid progenitor cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905457") -AnnotationAssertion(rdfs:label "negative regulation of lymphoid progenitor cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of lymphoid progenitor cell differentiation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:27010503") "Any process that activates or increases the frequency, rate or extent of lymphoid progenitor cell differentiation.") -AnnotationAssertion( "rz") -AnnotationAssertion( "2016-09-16T12:32:55Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of lymphoid progenitor cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of lymphoid progenitor cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of lymphoid progenitor cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of lymphoid progenitor cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905458") -AnnotationAssertion(rdfs:label "positive regulation of lymphoid progenitor cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of vascular associated smooth muscle cell apoptotic process) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_miRNA") Annotation( "GOC:TermGenie") Annotation( "GOC:rph") Annotation( "GO_REF:0000058") Annotation( "PMID:26493107") "Any process that modulates the frequency, rate or extent of vascular associated smooth muscle cell apoptotic process.") -AnnotationAssertion( "rph") -AnnotationAssertion( "2016-09-19T11:33:54Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of VSMC apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of vascular smooth muscle cell apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of VSMC apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of vascular associated smooth muscle cell apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of vascular smooth muscle cell apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905459") -AnnotationAssertion(rdfs:label "regulation of vascular associated smooth muscle cell apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of vascular associated smooth muscle cell apoptotic process) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_miRNA") Annotation( "GOC:TermGenie") Annotation( "GOC:rph") Annotation( "GO_REF:0000058") Annotation( "PMID:26493107") "Any process that stops, prevents or reduces the frequency, rate or extent of vascular associated smooth muscle cell apoptotic process.") -AnnotationAssertion( "rph") -AnnotationAssertion( "2016-09-19T11:34:03Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of VSMC apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of vascular associated smooth muscle cell apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of vascular smooth muscle cell apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of VSMC apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of vascular associated smooth muscle cell apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of vascular smooth muscle cell apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of VSMC apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of vascular associated smooth muscle cell apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of vascular smooth muscle cell apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of VSMC apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of vascular smooth muscle cell apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of VSMC apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of vascular associated smooth muscle cell apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of vascular smooth muscle cell apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of VSMC apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of vascular associated smooth muscle cell apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of vascular smooth muscle cell apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of VSMC apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of vascular associated smooth muscle cell apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of vascular smooth muscle cell apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of VSMC apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of VSMC apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of vascular associated smooth muscle cell apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of vascular associated smooth muscle cell apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of vascular smooth muscle cell apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of vascular smooth muscle cell apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of VSMC apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of vascular associated smooth muscle cell apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of vascular smooth muscle cell apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905460") -AnnotationAssertion(rdfs:label "negative regulation of vascular associated smooth muscle cell apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of vascular associated smooth muscle cell apoptotic process) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_miRNA") Annotation( "GOC:TermGenie") Annotation( "GOC:rph") Annotation( "GO_REF:0000058") Annotation( "PMID:26493107") "Any process that activates or increases the frequency, rate or extent of vascular associated smooth muscle cell apoptotic process.") -AnnotationAssertion( "rph") -AnnotationAssertion( "2016-09-19T11:34:10Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of VSMC apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of vascular smooth muscle cell apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of VSMC apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of vascular associated smooth muscle cell apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of vascular smooth muscle cell apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of VSMC apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of vascular associated smooth muscle cell apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of vascular smooth muscle cell apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of VSMC apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of vascular associated smooth muscle cell apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of vascular smooth muscle cell apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of VSMC apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of VSMC apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of vascular associated smooth muscle cell apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of vascular associated smooth muscle cell apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of vascular smooth muscle cell apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of vascular smooth muscle cell apoptotic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of VSMC apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of vascular associated smooth muscle cell apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of vascular smooth muscle cell apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of VSMC apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of vascular associated smooth muscle cell apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of vascular smooth muscle cell apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of VSMC apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of vascular associated smooth muscle cell apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of vascular smooth muscle cell apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of VSMC apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of vascular associated smooth muscle cell apoptosis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of vascular smooth muscle cell apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905461") -AnnotationAssertion(rdfs:label "positive regulation of vascular associated smooth muscle cell apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of protein localization to membrane) - -AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:TermGenie") Annotation( "GOC:bc") Annotation( "GO_REF:0000058") Annotation( "PMID:26911690") "Any process that modulates the frequency, rate or extent of protein localization to membrane.") -AnnotationAssertion( "bc") -AnnotationAssertion( "2016-09-21T16:20:03Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of protein localisation in membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of protein localization in membrane") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905475") -AnnotationAssertion(rdfs:label "regulation of protein localization to membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of protein localization to membrane) - -AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:TermGenie") Annotation( "GOC:bc") Annotation( "GO_REF:0000058") Annotation( "PMID:26911690") "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to membrane.") -AnnotationAssertion( "bc") -AnnotationAssertion( "2016-09-21T16:20:10Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of protein localisation in membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of protein localization in membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of protein localization to membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of protein localisation in membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of protein localization in membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of protein localization to membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of protein localisation in membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of protein localization in membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of protein localization to membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of protein localisation in membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of protein localization in membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of protein localisation in membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of protein localization in membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of protein localization to membrane") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905476") -AnnotationAssertion(rdfs:label "negative regulation of protein localization to membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of protein localization to membrane) - -AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:TermGenie") Annotation( "GOC:bc") Annotation( "GO_REF:0000058") Annotation( "PMID:26911690") "Any process that activates or increases the frequency, rate or extent of protein localization to membrane.") -AnnotationAssertion( "bc") -AnnotationAssertion( "2016-09-21T16:20:18Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of protein localisation in membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of protein localization in membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of protein localisation in membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of protein localization in membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of protein localization to membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of protein localisation in membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of protein localization in membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of protein localization to membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of protein localisation in membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of protein localization in membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of protein localization to membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of protein localisation in membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of protein localization in membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of protein localization to membrane") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905477") -AnnotationAssertion(rdfs:label "positive regulation of protein localization to membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of motor neuron migration) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:16516839") "Any process that modulates the frequency, rate or extent of motor neuron migration.") -AnnotationAssertion( "hbye") -AnnotationAssertion( "2016-09-23T12:49:54Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905483") -AnnotationAssertion(rdfs:label "regulation of motor neuron migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of motor neuron migration) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:16516839") "Any process that stops, prevents or reduces the frequency, rate or extent of motor neuron migration.") -AnnotationAssertion( "hbye") -AnnotationAssertion( "2016-09-23T12:50:11Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of motor neuron migration") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of motor neuron migration") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of motor neuron migration") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of motor neuron migration") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905484") -AnnotationAssertion(rdfs:label "negative regulation of motor neuron migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of motor neuron migration) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:16516839") "Any process that activates or increases the frequency, rate or extent of motor neuron migration.") -AnnotationAssertion( "hbye") -AnnotationAssertion( "2016-09-23T12:50:19Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of motor neuron migration") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of motor neuron migration") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of motor neuron migration") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of motor neuron migration") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905485") -AnnotationAssertion(rdfs:label "positive regulation of motor neuron migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of branching morphogenesis of a nerve) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:16516839") "Any process that activates or increases the frequency, rate or extent of branching morphogenesis of a nerve.") -AnnotationAssertion( "hbye") -AnnotationAssertion( "2016-09-23T14:11:52Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of branching morphogenesis of a nerve") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of branching morphogenesis of a nerve") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of branching morphogenesis of a nerve") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of branching morphogenesis of a nerve") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905492") -AnnotationAssertion(rdfs:label "positive regulation of branching morphogenesis of a nerve") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of motile cilium assembly) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:cilia") Annotation( "GOC:krc") Annotation( "GO_REF:0000058") Annotation( "PMID:25294941") "Any process that modulates the frequency, rate or extent of motile cilium assembly.") -AnnotationAssertion( "krc") -AnnotationAssertion( "2016-09-27T18:27:47Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of motile primary cilia assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of motile primary cilia formation") -AnnotationAssertion( "regulation of motile primary cilium assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of motile primary cilium formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of nodal cilium assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of nodal cilium formation") -AnnotationAssertion( "GO:1905503") -AnnotationAssertion(rdfs:label "regulation of motile cilium assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of motile cilium assembly) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:cilia") Annotation( "GOC:krc") Annotation( "GO_REF:0000058") Annotation( "PMID:25294941") "Any process that stops, prevents or reduces the frequency, rate or extent of motile cilium assembly.") -AnnotationAssertion( "krc") -AnnotationAssertion( "2016-09-27T18:27:55Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of motile primary cilia assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of motile primary cilia formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of motile primary cilium assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of motile primary cilium formation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of motile primary cilia assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of motile primary cilia formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of motile primary cilium assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of motile primary cilium formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of nodal cilium assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of nodal cilium formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of motile primary cilia assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of motile primary cilia formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of motile primary cilium assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of motile primary cilium formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of nodal cilium assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of nodal cilium formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of motile primary cilia assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of motile primary cilia formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of motile primary cilium assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of motile primary cilium formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of nodal cilium assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of nodal cilium formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of nodal cilium assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of nodal cilium formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of motile primary cilia assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of motile primary cilia formation") -AnnotationAssertion( "negative regulation of motile primary cilium assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of motile primary cilium formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of nodal cilium assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of nodal cilium formation") -AnnotationAssertion( "GO:1905504") -AnnotationAssertion(rdfs:label "negative regulation of motile cilium assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of motile cilium assembly) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:cilia") Annotation( "GOC:krc") Annotation( "GO_REF:0000058") Annotation( "PMID:25294941") "Any process that activates or increases the frequency, rate or extent of motile cilium assembly.") -AnnotationAssertion( "krc") -AnnotationAssertion( "2016-09-27T18:28:03Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of motile primary cilia assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of motile primary cilia formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of motile primary cilium assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of motile primary cilium formation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of nodal cilium assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of nodal cilium formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of motile primary cilia assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of motile primary cilia formation") -AnnotationAssertion( "positive regulation of motile primary cilium assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of motile primary cilium formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of nodal cilium assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of nodal cilium formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of motile primary cilia assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of motile primary cilia formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of motile primary cilium assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of motile primary cilium formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of nodal cilium assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of nodal cilium formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of motile primary cilia assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of motile primary cilia formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of motile primary cilium assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of motile primary cilium formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of nodal cilium assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of nodal cilium formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of motile primary cilia assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of motile primary cilia formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of motile primary cilium assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of motile primary cilium formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of nodal cilium assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of nodal cilium formation") -AnnotationAssertion( "GO:1905505") -AnnotationAssertion(rdfs:label "positive regulation of motile cilium assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (non-motile cilium assembly) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:cilia") Annotation( "GOC:kmv") Annotation( "GO_REF:0000079") Annotation( "PMID:14521833") Annotation( "PMID:14521834") "The aggregation, arrangement and bonding together of a set of components to form a non-motile cilium.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2016-09-30T11:55:15Z") -AnnotationAssertion( "GO:0035058") -AnnotationAssertion(Annotation( "GOC:TermGenie") "non-motile cilium formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "nonmotile cilium assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "nonmotile cilium formation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:bf") "immotile primary cilium assembly") -AnnotationAssertion(Annotation( "GOC:bf") "nonmotile primary cilia assembly") -AnnotationAssertion( "nonmotile primary cilium assembly") -AnnotationAssertion(Annotation( "GOC:kmv") "sensory cilium assembly") -AnnotationAssertion(Annotation( "GOC:mah") "sensory cilium biogenesis") -AnnotationAssertion( "GO:1905515") -AnnotationAssertion(rdfs:label "non-motile cilium assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of fertilization) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:hbye") Annotation( "GO_REF:0000058") Annotation( "PMID:27564576") "Any process that activates or increases the frequency, rate or extent of fertilization.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2016-09-30T14:32:32Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of syngamy") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of fertilization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of syngamy") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of fertilization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of syngamy") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of fertilization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of syngamy") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of fertilization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of syngamy") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905516") -AnnotationAssertion(rdfs:label "positive regulation of fertilization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (macrophage migration) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000091") Annotation( "PMID:25749876") "The orderly movement of a macrophage from one site to another.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2016-09-30T22:17:45Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905517") -AnnotationAssertion(rdfs:label "macrophage migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of macrophage migration) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:25749876") "Any process that modulates the frequency, rate or extent of macrophage migration.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2016-10-03T15:29:06Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905521") -AnnotationAssertion(rdfs:label "regulation of macrophage migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of macrophage migration) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:25749876") "Any process that stops, prevents or reduces the frequency, rate or extent of macrophage migration.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2016-10-03T15:29:14Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of macrophage migration") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of macrophage migration") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of macrophage migration") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of macrophage migration") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905522") -AnnotationAssertion(rdfs:label "negative regulation of macrophage migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of macrophage migration) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:25749876") "Any process that activates or increases the frequency, rate or extent of macrophage migration.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2016-10-03T15:29:21Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of macrophage migration") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of macrophage migration") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of macrophage migration") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of macrophage migration") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905523") -AnnotationAssertion(rdfs:label "positive regulation of macrophage migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of blood vessel branching) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_telomere") Annotation( "GOC:TermGenie") Annotation( "GOC:nc") Annotation( "GO_REF:0000058") Annotation( "PMID:23201774") "Any process that modulates the frequency, rate or extent of blood vessel branching.") -AnnotationAssertion( "nc") -AnnotationAssertion( "2016-10-12T14:19:33Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of branching involved in blood vessel morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905553") -AnnotationAssertion(rdfs:label "regulation of blood vessel branching") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of vessel branching) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_telomere") Annotation( "GOC:TermGenie") Annotation( "GOC:nc") Annotation( "GO_REF:0000058") Annotation( "PMID:23201774") "Any process that stops, prevents or reduces the frequency, rate or extent of blood vessel branching.") -AnnotationAssertion( "nc") -AnnotationAssertion( "2016-10-12T14:19:41Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of branching involved in blood vessel morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of patterning of blood vessels") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of branching involved in blood vessel morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of patterning of blood vessels") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of branching involved in blood vessel morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of patterning of blood vessels") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of branching involved in blood vessel morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of branching involved in blood vessel morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of patterning of blood vessels") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905554") -AnnotationAssertion(rdfs:label "negative regulation of vessel branching") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of blood vessel branching) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_telomere") Annotation( "GOC:TermGenie") Annotation( "GOC:nc") Annotation( "GO_REF:0000058") Annotation( "PMID:23201774") "Any process that activates or increases the frequency, rate or extent of blood vessel branching.") -AnnotationAssertion( "nc") -AnnotationAssertion( "2016-10-12T14:19:49Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of branching involved in blood vessel morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of branching involved in blood vessel morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of patterning of blood vessels") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of branching involved in blood vessel morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of patterning of blood vessels") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of branching involved in blood vessel morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of patterning of blood vessels") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of branching involved in blood vessel morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of patterning of blood vessels") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905555") -AnnotationAssertion(rdfs:label "positive regulation of blood vessel branching") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of mitotic nuclear envelope disassembly) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:18765790") "Any process that modulates the frequency, rate or extent of mitotic nuclear envelope disassembly.") -AnnotationAssertion( "hbye") -AnnotationAssertion( "2016-10-14T13:14:57Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of mitotic nuclear envelope breakdown") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of mitotic nuclear envelope catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of mitotic nuclear envelope degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905557") -AnnotationAssertion(rdfs:label "regulation of mitotic nuclear envelope disassembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of mitotic nuclear envelope disassembly) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:18765790") "Any process that stops, prevents or reduces the frequency, rate or extent of mitotic nuclear envelope disassembly.") -AnnotationAssertion( "hbye") -AnnotationAssertion( "2016-10-14T13:15:08Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of mitotic nuclear envelope breakdown") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of mitotic nuclear envelope catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of mitotic nuclear envelope degradation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of mitotic nuclear envelope disassembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of mitotic nuclear envelope breakdown") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of mitotic nuclear envelope catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of mitotic nuclear envelope degradation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of mitotic nuclear envelope disassembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of mitotic nuclear envelope breakdown") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of mitotic nuclear envelope catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of mitotic nuclear envelope degradation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of mitotic nuclear envelope disassembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of mitotic nuclear envelope breakdown") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of mitotic nuclear envelope catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of mitotic nuclear envelope degradation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of mitotic nuclear envelope breakdown") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of mitotic nuclear envelope catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of mitotic nuclear envelope degradation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of mitotic nuclear envelope disassembly") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905558") -AnnotationAssertion(rdfs:label "negative regulation of mitotic nuclear envelope disassembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of mitotic nuclear envelope disassembly) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:18765790") "Any process that activates or increases the frequency, rate or extent of mitotic nuclear envelope disassembly.") -AnnotationAssertion( "hbye") -AnnotationAssertion( "2016-10-14T13:15:17Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of mitotic nuclear envelope breakdown") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of mitotic nuclear envelope catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of mitotic nuclear envelope degradation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of mitotic nuclear envelope breakdown") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of mitotic nuclear envelope catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of mitotic nuclear envelope degradation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of mitotic nuclear envelope disassembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of mitotic nuclear envelope breakdown") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of mitotic nuclear envelope catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of mitotic nuclear envelope degradation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of mitotic nuclear envelope disassembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of mitotic nuclear envelope breakdown") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of mitotic nuclear envelope catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of mitotic nuclear envelope degradation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of mitotic nuclear envelope disassembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of mitotic nuclear envelope breakdown") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of mitotic nuclear envelope catabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of mitotic nuclear envelope degradation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of mitotic nuclear envelope disassembly") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905559") -AnnotationAssertion(rdfs:label "positive regulation of mitotic nuclear envelope disassembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of vascular endothelial cell proliferation) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_telomere") Annotation( "GOC:TermGenie") Annotation( "GOC:nc") Annotation( "GO_REF:0000058") Annotation( "PMID:23201774") "Any process that modulates the frequency, rate or extent of vascular endothelial cell proliferation.") -AnnotationAssertion( "nc") -AnnotationAssertion( "2016-10-17T09:24:17Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905562") -AnnotationAssertion(rdfs:label "regulation of vascular endothelial cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of vascular endothelial cell proliferation) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_telomere") Annotation( "GOC:TermGenie") Annotation( "GOC:nc") Annotation( "GO_REF:0000058") Annotation( "PMID:23201774") "Any process that stops, prevents or reduces the frequency, rate or extent of vascular endothelial cell proliferation.") -AnnotationAssertion( "nc") -AnnotationAssertion( "2016-10-17T09:24:26Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of vascular endothelial cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of vascular endothelial cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of vascular endothelial cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of vascular endothelial cell proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905563") -AnnotationAssertion(rdfs:label "negative regulation of vascular endothelial cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of vascular endothelial cell proliferation) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_telomere") Annotation( "GOC:TermGenie") Annotation( "GOC:nc") Annotation( "GO_REF:0000058") Annotation( "PMID:23201774") "Any process that activates or increases the frequency, rate or extent of vascular endothelial cell proliferation.") -AnnotationAssertion( "nc") -AnnotationAssertion( "2016-10-17T09:24:35Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of vascular endothelial cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of vascular endothelial cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of vascular endothelial cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of vascular endothelial cell proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905564") -AnnotationAssertion(rdfs:label "positive regulation of vascular endothelial cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of presynapse assembly) - -AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:TermGenie") Annotation( "GOC:bc") Annotation( "GO_REF:0000058") Annotation( "PMID:25533483") "Any process that modulates the frequency, rate or extent of presynapse assembly.") -AnnotationAssertion( "bc") -AnnotationAssertion( "2016-10-27T16:08:13Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of presynapse biogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of presynaptic terminal assembly") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905606") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "regulation of presynapse assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (negative regulation of presynapse assembly) - -AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:TermGenie") Annotation( "GOC:bc") Annotation( "GO_REF:0000058") Annotation( "PMID:25533483") "Any process that stops, prevents or reduces the frequency, rate or extent of presynapse assembly.") -AnnotationAssertion( "bc") -AnnotationAssertion( "2016-10-27T16:08:20Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of presynapse assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of presynapse biogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of presynaptic terminal assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of presynapse assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of presynapse biogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of presynaptic terminal assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of presynapse assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of presynapse biogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of presynaptic terminal assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of presynapse biogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of presynaptic terminal assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of presynapse assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of presynapse biogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of presynaptic terminal assembly") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905607") -AnnotationAssertion(rdfs:label "negative regulation of presynapse assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of presynapse assembly) - -AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:TermGenie") Annotation( "GOC:bc") Annotation( "GO_REF:0000058") Annotation( "PMID:25533483") "Any process that activates or increases the frequency, rate or extent of presynapse assembly.") -AnnotationAssertion( "bc") -AnnotationAssertion( "2016-10-27T16:08:28Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of presynapse biogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of presynaptic terminal assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of presynapse assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of presynapse biogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of presynaptic terminal assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of presynapse assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of presynapse biogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of presynaptic terminal assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of presynapse assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of presynapse biogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of presynaptic terminal assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of presynapse assembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of presynapse biogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of presynaptic terminal assembly") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905608") -AnnotationAssertion(rdfs:label "positive regulation of presynapse assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of serotonin biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:TermGenie") Annotation( "GOC:pad") Annotation( "GO_REF:0000058") Annotation( "PMID:25642596") "Any process that modulates the frequency, rate or extent of serotonin biosynthetic process.") -AnnotationAssertion( "pad") -AnnotationAssertion( "2016-10-31T14:26:20Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of serotonin anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of serotonin biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of serotonin formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of serotonin synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905627") -AnnotationAssertion(rdfs:label "regulation of serotonin biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of serotonin biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:TermGenie") Annotation( "GOC:pad") Annotation( "GO_REF:0000058") Annotation( "PMID:25642596") "Any process that stops, prevents or reduces the frequency, rate or extent of serotonin biosynthetic process.") -AnnotationAssertion( "pad") -AnnotationAssertion( "2016-10-31T14:26:28Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of serotonin anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of serotonin biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of serotonin biosynthetic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of serotonin formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of serotonin synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of serotonin anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of serotonin biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of serotonin biosynthetic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of serotonin formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of serotonin synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of serotonin anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of serotonin biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of serotonin biosynthetic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of serotonin formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of serotonin synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of serotonin anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of serotonin biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of serotonin formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of serotonin synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of serotonin anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of serotonin biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of serotonin biosynthetic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of serotonin formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of serotonin synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905628") -AnnotationAssertion(rdfs:label "negative regulation of serotonin biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of serotonin biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:TermGenie") Annotation( "GOC:pad") Annotation( "GO_REF:0000058") Annotation( "PMID:25642596") "Any process that activates or increases the frequency, rate or extent of serotonin biosynthetic process.") -AnnotationAssertion( "pad") -AnnotationAssertion( "2016-10-31T14:26:36Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of serotonin anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of serotonin biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of serotonin formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of serotonin synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of serotonin anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of serotonin biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of serotonin biosynthetic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of serotonin formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of serotonin synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of serotonin anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of serotonin biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of serotonin biosynthetic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of serotonin formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of serotonin synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of serotonin anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of serotonin biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of serotonin biosynthetic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of serotonin formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of serotonin synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of serotonin anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of serotonin biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of serotonin biosynthetic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of serotonin formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of serotonin synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905629") -AnnotationAssertion(rdfs:label "positive regulation of serotonin biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (protein localization to euchromatin) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000087") Annotation( "PMID:20889714") "A process in which a protein is transported to, or maintained in, a location within an euchromatin.") -AnnotationAssertion( "pga") -AnnotationAssertion( "2016-11-01T16:16:14Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "protein localisation in euchromatin") -AnnotationAssertion(Annotation( "GOC:TermGenie") "protein localisation to euchromatin") -AnnotationAssertion(Annotation( "GOC:TermGenie") "protein localization in euchromatin") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905632") -AnnotationAssertion(rdfs:label "protein localization to euchromatin") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (establishment of protein localization to euchromatin) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000087") Annotation( "PMID:20889714") "The directed movement of a protein to a specific location in an euchromatin.") -AnnotationAssertion( "pga") -AnnotationAssertion( "2016-11-01T16:16:22Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "establishment of protein localisation in euchromatin") -AnnotationAssertion(Annotation( "GOC:TermGenie") "establishment of protein localisation to euchromatin") -AnnotationAssertion(Annotation( "GOC:TermGenie") "establishment of protein localization in euchromatin") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905633") -AnnotationAssertion(rdfs:label "establishment of protein localization to euchromatin") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of protein localization to chromatin) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:20889714") "Any process that modulates the frequency, rate or extent of protein localization to chromatin.") -AnnotationAssertion( "pga") -AnnotationAssertion( "2016-11-01T16:33:52Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of protein localisation to chromatin") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905634") -AnnotationAssertion(rdfs:label "regulation of protein localization to chromatin") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of artery morphogenesis) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_miRNA") Annotation( "GOC:TermGenie") Annotation( "GOC:rph") Annotation( "GO_REF:0000058") Annotation( "PMID:27389411") "Any process that modulates the frequency, rate or extent of artery morphogenesis.") -AnnotationAssertion( "rph") -AnnotationAssertion( "2016-11-09T12:19:37Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of arterial morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of arteriogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905651") -AnnotationAssertion(rdfs:label "regulation of artery morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of artery morphogenesis) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_miRNA") Annotation( "GOC:TermGenie") Annotation( "GOC:rph") Annotation( "GO_REF:0000058") Annotation( "PMID:27389411") "Any process that stops, prevents or reduces the frequency, rate or extent of artery morphogenesis.") -AnnotationAssertion( "rph") -AnnotationAssertion( "2016-11-09T12:19:53Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of arterial morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of arteriogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of artery morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of arterial morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of arteriogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of artery morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of arterial morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of arteriogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of artery morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of arterial morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of arteriogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of arterial morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of arteriogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of artery morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905652") -AnnotationAssertion(rdfs:label "negative regulation of artery morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of artery morphogenesis) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_miRNA") Annotation( "GOC:TermGenie") Annotation( "GOC:rph") Annotation( "GO_REF:0000058") Annotation( "PMID:27389411") "Any process that activates or increases the frequency, rate or extent of artery morphogenesis.") -AnnotationAssertion( "rph") -AnnotationAssertion( "2016-11-09T12:20:01Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of arterial morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of arteriogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of arterial morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of arteriogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of artery morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of arterial morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of arteriogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of artery morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of arterial morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of arteriogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of artery morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of arterial morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of arteriogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of artery morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905653") -AnnotationAssertion(rdfs:label "positive regulation of artery morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of calcium ion import across plasma membrane) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:bhm") Annotation( "GO_REF:0000058") Annotation( "PMID:17640527") "Any process that modulates the frequency, rate or extent of calcium ion import across plasma membrane.") -AnnotationAssertion( "bhm") -AnnotationAssertion( "2016-11-11T09:26:06Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905664") -AnnotationAssertion(rdfs:comment "An example of this is PPP3CA in human (Q08209) in 17640527 (inferred from direct assay).") -AnnotationAssertion(rdfs:label "regulation of calcium ion import across plasma membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of calcium ion import across plasma membrane) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:bhm") Annotation( "GO_REF:0000058") Annotation( "PMID:17640527") "Any process that activates or increases the frequency, rate or extent of calcium ion import across plasma membrane.") -AnnotationAssertion( "bhm") -AnnotationAssertion( "2016-11-11T09:26:23Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of calcium ion import across plasma membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of calcium ion import across plasma membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of calcium ion import across plasma membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of calcium ion import across plasma membrane") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905665") -AnnotationAssertion(rdfs:comment "An example of this is PPP3CA in human (Q08209) in 17640527 (inferred from direct assay).") -AnnotationAssertion(rdfs:label "positive regulation of calcium ion import across plasma membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of lysosome organization) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:25561470") "Any process that modulates the frequency, rate or extent of lysosome organization.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2016-11-11T22:01:04Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of lysosome organisation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of lysosome organization and biogenesis") -AnnotationAssertion( "GO:1905671") -AnnotationAssertion(rdfs:label "regulation of lysosome organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of lysosome organization) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:25561470") "Any process that stops, prevents or reduces the frequency, rate or extent of lysosome organization.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2016-11-11T22:01:12Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of lysosome organisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of lysosome organization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of lysosome organisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of lysosome organization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of lysosome organisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of lysosome organization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of lysosome organisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of lysosome organisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of lysosome organization") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of lysosome organization and biogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of lysosome organization and biogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of lysosome organization and biogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of lysosome organization and biogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of lysosome organization and biogenesis") -AnnotationAssertion( "GO:1905672") -AnnotationAssertion(rdfs:label "negative regulation of lysosome organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of lysosome organization) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:25561470") "Any process that activates or increases the frequency, rate or extent of lysosome organization.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2016-11-11T22:01:20Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of lysosome organisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of lysosome organisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of lysosome organization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of lysosome organisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of lysosome organization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of lysosome organisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of lysosome organization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of lysosome organisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of lysosome organization") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of lysosome organization and biogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of lysosome organization and biogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of lysosome organization and biogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of lysosome organization and biogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of lysosome organization and biogenesis") -AnnotationAssertion( "GO:1905673") -AnnotationAssertion(rdfs:label "positive regulation of lysosome organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (nucleus disassembly) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:autophagy") Annotation( "GOC:pr") Annotation( "GO_REF:0000079") "The disaggregation of a nucleus into its constituent components.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2016-11-14T13:38:57Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "cell nucleus disassembly") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905690") -AnnotationAssertion(rdfs:label "nucleus disassembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (cytoplasmic microtubule bundle) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000064") Annotation( "PMID:11007487") Annotation( "PMID:26124291") "Any microtubule bundle that is part of a cytoplasm.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2016-11-24T16:52:02Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "microtubule bundle of cytoplasm") -AnnotationAssertion(Annotation( "GOC:TermGenie") "microtubule fascicle of cytoplasm") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:1905720") -AnnotationAssertion(rdfs:label "cytoplasmic microtubule bundle") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of saliva secretion) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:23419067") "Any process that stops, prevents or reduces the frequency, rate or extent of saliva secretion.") -AnnotationAssertion( "pga") -AnnotationAssertion( "2016-12-09T10:24:00Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of saliva secretion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of salivation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of saliva secretion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of salivation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of saliva secretion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of salivation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of salivation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of saliva secretion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of salivation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905747") -AnnotationAssertion(rdfs:label "negative regulation of saliva secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (hard palate morphogenesis) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000083") Annotation( "PMID:23419067") "The developmental process by which a hard palate is generated and organized.") -AnnotationAssertion( "pga") -AnnotationAssertion( "2016-12-09T12:22:24Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "palatum durum morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905748") -AnnotationAssertion(rdfs:label "hard palate morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (protein localization to cytoplasmic microtubule) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000087") Annotation( "PMID:15177031") "A process in which a protein is transported to, or maintained in, a location within a cytoplasmic microtubule.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2016-12-12T15:31:07Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "protein localisation to cytoplasmic microtubule") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905755") -AnnotationAssertion(rdfs:label "protein localization to cytoplasmic microtubule") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of mesodermal cell differentiation) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_miRNA") Annotation( "GOC:TermGenie") Annotation( "GOC:rph") Annotation( "GO_REF:0000058") Annotation( "PMID:23765923") "Any process that modulates the frequency, rate or extent of mesodermal cell differentiation.") -AnnotationAssertion( "rph") -AnnotationAssertion( "2016-12-21T12:44:13Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of mesoderm cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905770") -AnnotationAssertion(rdfs:label "regulation of mesodermal cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of mesodermal cell differentiation) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_miRNA") Annotation( "GOC:TermGenie") Annotation( "GOC:rph") Annotation( "GO_REF:0000058") Annotation( "PMID:23765923") "Any process that stops, prevents or reduces the frequency, rate or extent of mesodermal cell differentiation.") -AnnotationAssertion( "rph") -AnnotationAssertion( "2016-12-21T12:44:23Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of mesoderm cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of mesodermal cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of mesoderm cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of mesodermal cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of mesoderm cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of mesodermal cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of mesoderm cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of mesoderm cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of mesodermal cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905771") -AnnotationAssertion(rdfs:label "negative regulation of mesodermal cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of mesodermal cell differentiation) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_miRNA") Annotation( "GOC:TermGenie") Annotation( "GOC:rph") Annotation( "GO_REF:0000058") Annotation( "PMID:23765923") "Any process that activates or increases the frequency, rate or extent of mesodermal cell differentiation.") -AnnotationAssertion( "rph") -AnnotationAssertion( "2016-12-21T12:44:32Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of mesoderm cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of mesoderm cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of mesodermal cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of mesoderm cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of mesodermal cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of mesoderm cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of mesodermal cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of mesoderm cell differentiation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of mesodermal cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905772") -AnnotationAssertion(rdfs:label "positive regulation of mesodermal cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of detection of mechanical stimulus involved in sensory perception of touch) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:8692859") "Any process that modulates the frequency, rate or extent of detection of mechanical stimulus involved in sensory perception of touch.") -AnnotationAssertion( "hbye") -AnnotationAssertion( "2017-01-09T15:11:04Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of perception of touch, detection of mechanical stimulus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of perception of touch, sensory detection of mechanical stimulus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of perception of touch, sensory transduction of mechanical stimulus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of sensory detection of mechanical stimulus during perception of touch") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of sensory transduction of mechanical stimulus during perception of touch") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of tactition, sensory detection of mechanical stimulus") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905787") -AnnotationAssertion(rdfs:label "regulation of detection of mechanical stimulus involved in sensory perception of touch") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (negative regulation of detection of mechanical stimulus involved in sensory perception of touch) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:8692859") "Any process that stops, prevents or reduces the frequency, rate or extent of detection of mechanical stimulus involved in sensory perception of touch.") -AnnotationAssertion( "hbye") -AnnotationAssertion( "2017-01-09T15:11:14Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of detection of mechanical stimulus involved in sensory perception of touch") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of perception of touch, detection of mechanical stimulus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of perception of touch, sensory detection of mechanical stimulus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of perception of touch, sensory transduction of mechanical stimulus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of sensory detection of mechanical stimulus during perception of touch") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of sensory transduction of mechanical stimulus during perception of touch") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of tactition, sensory detection of mechanical stimulus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of detection of mechanical stimulus involved in sensory perception of touch") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of perception of touch, detection of mechanical stimulus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of perception of touch, sensory detection of mechanical stimulus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of perception of touch, sensory transduction of mechanical stimulus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of sensory detection of mechanical stimulus during perception of touch") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of sensory transduction of mechanical stimulus during perception of touch") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of tactition, sensory detection of mechanical stimulus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of detection of mechanical stimulus involved in sensory perception of touch") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of perception of touch, detection of mechanical stimulus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of perception of touch, sensory detection of mechanical stimulus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of perception of touch, sensory transduction of mechanical stimulus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of sensory detection of mechanical stimulus during perception of touch") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of sensory transduction of mechanical stimulus during perception of touch") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of tactition, sensory detection of mechanical stimulus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of perception of touch, detection of mechanical stimulus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of perception of touch, sensory detection of mechanical stimulus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of perception of touch, sensory transduction of mechanical stimulus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of sensory detection of mechanical stimulus during perception of touch") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of sensory transduction of mechanical stimulus during perception of touch") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of tactition, sensory detection of mechanical stimulus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of detection of mechanical stimulus involved in sensory perception of touch") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of perception of touch, detection of mechanical stimulus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of perception of touch, sensory detection of mechanical stimulus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of perception of touch, sensory transduction of mechanical stimulus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of sensory detection of mechanical stimulus during perception of touch") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of sensory transduction of mechanical stimulus during perception of touch") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of tactition, sensory detection of mechanical stimulus") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905788") -AnnotationAssertion(rdfs:label "negative regulation of detection of mechanical stimulus involved in sensory perception of touch") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of detection of mechanical stimulus involved in sensory perception of touch) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:8692859") "Any process that activates or increases the frequency, rate or extent of detection of mechanical stimulus involved in sensory perception of touch.") -AnnotationAssertion( "hbye") -AnnotationAssertion( "2017-01-09T15:11:23Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of perception of touch, detection of mechanical stimulus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of perception of touch, sensory detection of mechanical stimulus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of perception of touch, sensory transduction of mechanical stimulus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of sensory detection of mechanical stimulus during perception of touch") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of sensory transduction of mechanical stimulus during perception of touch") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of tactition, sensory detection of mechanical stimulus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of detection of mechanical stimulus involved in sensory perception of touch") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of perception of touch, detection of mechanical stimulus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of perception of touch, sensory detection of mechanical stimulus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of perception of touch, sensory transduction of mechanical stimulus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of sensory detection of mechanical stimulus during perception of touch") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of sensory transduction of mechanical stimulus during perception of touch") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of tactition, sensory detection of mechanical stimulus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of detection of mechanical stimulus involved in sensory perception of touch") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of perception of touch, detection of mechanical stimulus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of perception of touch, sensory detection of mechanical stimulus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of perception of touch, sensory transduction of mechanical stimulus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of sensory detection of mechanical stimulus during perception of touch") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of sensory transduction of mechanical stimulus during perception of touch") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of tactition, sensory detection of mechanical stimulus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of detection of mechanical stimulus involved in sensory perception of touch") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of perception of touch, detection of mechanical stimulus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of perception of touch, sensory detection of mechanical stimulus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of perception of touch, sensory transduction of mechanical stimulus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of sensory detection of mechanical stimulus during perception of touch") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of sensory transduction of mechanical stimulus during perception of touch") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of tactition, sensory detection of mechanical stimulus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of detection of mechanical stimulus involved in sensory perception of touch") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of perception of touch, detection of mechanical stimulus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of perception of touch, sensory detection of mechanical stimulus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of perception of touch, sensory transduction of mechanical stimulus") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of sensory detection of mechanical stimulus during perception of touch") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of sensory transduction of mechanical stimulus during perception of touch") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of tactition, sensory detection of mechanical stimulus") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905789") -AnnotationAssertion(rdfs:label "positive regulation of detection of mechanical stimulus involved in sensory perception of touch") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (excitatory synapse pruning) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000079") Annotation( "PMID:27779093") "The disaggregation of an excitatory synapse into its constituent components.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2017-01-11T22:03:06Z") -AnnotationAssertion( "synapse clearance") -AnnotationAssertion( "synapse disassembly") -AnnotationAssertion( "synapse elimination") -AnnotationAssertion( "synapse removal") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905805") -AnnotationAssertion(rdfs:label "excitatory synapse pruning") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of synapse pruning) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:27779093") "Any process that modulates the frequency, rate or extent of synapse pruning.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2017-01-11T22:03:15Z") -AnnotationAssertion( "regulation of synapse clearance") -AnnotationAssertion(Annotation( ) "regulation of synapse disassembly") -AnnotationAssertion( "regulation of synapse elimination") -AnnotationAssertion( "regulation of synapse removal") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905806") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "regulation of synapse pruning") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of synapse pruning) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:27779093") "Any process that stops, prevents or reduces the frequency, rate or extent of synapse pruning.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2017-01-11T22:03:24Z") -AnnotationAssertion( "regulation of synapse clearance") -AnnotationAssertion( "regulation of synapse disassembly") -AnnotationAssertion( "regulation of synapse elimination") -AnnotationAssertion( "regulation of synapse removal") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of synapse disassembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of synapse disassembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of synapse disassembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of synapse disassembly") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905807") -AnnotationAssertion(rdfs:label "negative regulation of synapse pruning") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of synapse pruning) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:27779093") "Any process that activates or increases the frequency, rate or extent of synapse pruning.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2017-01-11T22:03:33Z") -AnnotationAssertion( "regulation of synapse clearance") -AnnotationAssertion( "regulation of synapse disassembly") -AnnotationAssertion( "regulation of synapse elimination") -AnnotationAssertion( "regulation of synapse removal") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of synapse disassembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of synapse disassembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of synapse disassembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of synapse disassembly") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905808") -AnnotationAssertion(rdfs:label "positive regulation of synapse pruning") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of synapse organization) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:27779093") "Any process that stops, prevents or reduces the frequency, rate or extent of synapse organization.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2017-01-11T22:03:41Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of synapse development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of synapse organisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of synapse organization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of synapse development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of synapse organisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of synapse organization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of synapse development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of synapse organisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of synapse organization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of synapse development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of synapse organisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of synapse development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of synapse organisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of synapse organization") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of synapse morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of synapse organization and biogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of synapse morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of synapse organization and biogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of synapse morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of synapse organization and biogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of synapse morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of synapse organization and biogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of synapse morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of synapse organization and biogenesis") -AnnotationAssertion( "GO:1905809") -AnnotationAssertion(rdfs:label "negative regulation of synapse organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of excitatory synapse pruning) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:27779093") "Any process that modulates the frequency, rate or extent of excitatory synapse pruning.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2017-01-12T02:38:27Z") -AnnotationAssertion( "regulation of synapse clearance") -AnnotationAssertion( "regulation of synapse disassembly") -AnnotationAssertion( "regulation of synapse elimination") -AnnotationAssertion( "regulation of synapse removal") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905810") -AnnotationAssertion(rdfs:label "regulation of excitatory synapse pruning") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of excitatory synapse pruning) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:27779093") "Any process that stops, prevents or reduces the frequency, rate or extent of excitatory synapse pruning.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2017-01-12T02:38:36Z") -AnnotationAssertion( "regulation of synapse clearance") -AnnotationAssertion( "regulation of synapse disassembly") -AnnotationAssertion( "regulation of synapse elimination") -AnnotationAssertion( "regulation of synapse removal") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of excitatory synapse disassembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of excitatory synapse disassembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of excitatory synapse disassembly") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of excitatory synapse disassembly") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905811") -AnnotationAssertion(rdfs:label "negative regulation of excitatory synapse pruning") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of chromosome condensation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:bhm") Annotation( "GO_REF:0000058") Annotation( "PMID:17268547") "Any process that activates or increases the frequency, rate or extent of chromosome condensation.") -AnnotationAssertion( "bhm") -AnnotationAssertion( "2017-01-13T14:13:44Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of eukaryotic chromosome condensation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of nuclear chromosome condensation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of chromosome condensation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of eukaryotic chromosome condensation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of nuclear chromosome condensation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of chromosome condensation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of eukaryotic chromosome condensation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of nuclear chromosome condensation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of chromosome condensation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of eukaryotic chromosome condensation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of nuclear chromosome condensation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of chromosome condensation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of eukaryotic chromosome condensation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of nuclear chromosome condensation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905821") -AnnotationAssertion(rdfs:label "positive regulation of chromosome condensation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of microtubule nucleation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:27689799") "Any process that stops, prevents or reduces the frequency, rate or extent of microtubule nucleation.") -AnnotationAssertion( "hbye") -AnnotationAssertion( "2017-01-17T12:00:56Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of microtubule nucleation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of microtubule nucleation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of microtubule nucleation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of microtubule nucleation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905833") -AnnotationAssertion(rdfs:label "negative regulation of microtubule nucleation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (epididymis development) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000094") Annotation( "PMID:12388089") "The process whose specific outcome is the progression of an epididymis over time, from its formation to the mature structure.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2017-01-27T00:00:33Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "epididymus development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905867") -AnnotationAssertion(rdfs:label "epididymis development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of protein localization to cell leading edge) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:26324884") "Any process that modulates the frequency, rate or extent of protein localization to cell leading edge.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2017-01-27T19:34:55Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of protein localisation in cell leading edge") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of protein localisation to cell leading edge") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of protein localization in cell leading edge") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905871") -AnnotationAssertion(rdfs:label "regulation of protein localization to cell leading edge") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of protein localization to cell leading edge) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:26324884") "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell leading edge.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2017-01-27T19:35:04Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of protein localisation in cell leading edge") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of protein localisation to cell leading edge") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of protein localization in cell leading edge") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of protein localization to cell leading edge") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of protein localisation in cell leading edge") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of protein localisation to cell leading edge") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of protein localization in cell leading edge") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of protein localization to cell leading edge") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of protein localisation in cell leading edge") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of protein localisation to cell leading edge") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of protein localization in cell leading edge") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of protein localization to cell leading edge") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of protein localisation in cell leading edge") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of protein localisation to cell leading edge") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of protein localization in cell leading edge") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of protein localisation in cell leading edge") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of protein localisation to cell leading edge") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of protein localization in cell leading edge") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of protein localization to cell leading edge") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905872") -AnnotationAssertion(rdfs:label "negative regulation of protein localization to cell leading edge") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of protein localization to cell leading edge) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:26324884") "Any process that activates or increases the frequency, rate or extent of protein localization to cell leading edge.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2017-01-27T19:35:13Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of protein localisation in cell leading edge") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of protein localisation to cell leading edge") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of protein localization in cell leading edge") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of protein localisation in cell leading edge") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of protein localisation to cell leading edge") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of protein localization in cell leading edge") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of protein localization to cell leading edge") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of protein localisation in cell leading edge") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of protein localisation to cell leading edge") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of protein localization in cell leading edge") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of protein localization to cell leading edge") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of protein localisation in cell leading edge") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of protein localisation to cell leading edge") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of protein localization in cell leading edge") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of protein localization to cell leading edge") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of protein localisation in cell leading edge") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of protein localisation to cell leading edge") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of protein localization in cell leading edge") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of protein localization to cell leading edge") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905873") -AnnotationAssertion(rdfs:label "positive regulation of protein localization to cell leading edge") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of oogenesis) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:26434723") "Any process that modulates the frequency, rate or extent of oogenesis.") -AnnotationAssertion( "hbye") -AnnotationAssertion( "2017-01-31T09:31:05Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of ovum development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905879") -AnnotationAssertion(rdfs:label "regulation of oogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (negative regulation of oogenesis) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:26434723") "Any process that stops, prevents or reduces the frequency, rate or extent of oogenesis.") -AnnotationAssertion( "hbye") -AnnotationAssertion( "2017-01-31T09:31:15Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of oogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of ovum development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of oogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of ovum development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of oogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of ovum development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of ovum development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of oogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of ovum development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905880") -AnnotationAssertion(rdfs:label "negative regulation of oogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of oogenesis) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:26434723") "Any process that activates or increases the frequency, rate or extent of oogenesis.") -AnnotationAssertion( "hbye") -AnnotationAssertion( "2017-01-31T09:31:23Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of ovum development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of oogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of ovum development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of oogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of ovum development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of oogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of ovum development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of oogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of ovum development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905881") -AnnotationAssertion(rdfs:label "positive regulation of oogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (regulation of smooth muscle tissue development) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:bhm") Annotation( "GO_REF:0000058") Annotation( "PMID:14709716") "Any process that modulates the frequency, rate or extent of smooth muscle tissue development.") -AnnotationAssertion( "bhm") -AnnotationAssertion( "2017-02-01T14:31:16Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905899") -AnnotationAssertion(rdfs:label "regulation of smooth muscle tissue development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of smooth muscle tissue development) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:bhm") Annotation( "GO_REF:0000058") Annotation( "PMID:14709716") "Any process that stops, prevents or reduces the frequency, rate or extent of smooth muscle tissue development.") -AnnotationAssertion( "bhm") -AnnotationAssertion( "2017-02-01T14:31:24Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of smooth muscle tissue development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of smooth muscle tissue development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of smooth muscle tissue development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of smooth muscle tissue development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905900") -AnnotationAssertion(rdfs:label "negative regulation of smooth muscle tissue development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of smooth muscle tissue development) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:bhm") Annotation( "GO_REF:0000058") Annotation( "PMID:14709716") "Any process that activates or increases the frequency, rate or extent of smooth muscle tissue development.") -AnnotationAssertion( "bhm") -AnnotationAssertion( "2017-02-01T14:31:33Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of smooth muscle tissue development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of smooth muscle tissue development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of smooth muscle tissue development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of smooth muscle tissue development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905901") -AnnotationAssertion(rdfs:label "positive regulation of smooth muscle tissue development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of mesoderm formation) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_miRNA") Annotation( "GOC:TermGenie") Annotation( "GOC:rph") Annotation( "GO_REF:0000058") Annotation( "PMID:23939491") "Any process that modulates the frequency, rate or extent of mesoderm formation.") -AnnotationAssertion( "rph") -AnnotationAssertion( "2017-02-03T12:28:20Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905902") -AnnotationAssertion(rdfs:label "regulation of mesoderm formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of mesoderm formation) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_miRNA") Annotation( "GOC:TermGenie") Annotation( "GOC:rph") Annotation( "GO_REF:0000058") Annotation( "PMID:23939491") "Any process that stops, prevents or reduces the frequency, rate or extent of mesoderm formation.") -AnnotationAssertion( "rph") -AnnotationAssertion( "2017-02-03T12:28:29Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of mesoderm formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of mesoderm formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of mesoderm formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of mesoderm formation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905903") -AnnotationAssertion(rdfs:label "negative regulation of mesoderm formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of mesoderm formation) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_miRNA") Annotation( "GOC:TermGenie") Annotation( "GOC:rph") Annotation( "GO_REF:0000058") Annotation( "PMID:23939491") "Any process that activates or increases the frequency, rate or extent of mesoderm formation.") -AnnotationAssertion( "rph") -AnnotationAssertion( "2017-02-03T12:28:38Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of mesoderm formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of mesoderm formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of mesoderm formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of mesoderm formation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905904") -AnnotationAssertion(rdfs:label "positive regulation of mesoderm formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (pharyngeal gland morphogenesis) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000083") Annotation( "PMID:21868609") "The developmental process by which a pharyngeal gland is generated and organized.") -AnnotationAssertion( "rz") -AnnotationAssertion( "2017-02-03T14:39:10Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "pharynx gland morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "glandulae pharyngeae morphogenesis") -AnnotationAssertion( "GO:1905905") -AnnotationAssertion(rdfs:label "pharyngeal gland morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of calcium ion export across plasma membrane) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_miRNA") Annotation( "GOC:TermGenie") Annotation( "GOC:rph") Annotation( "GO_REF:0000058") Annotation( "PMID:22362515") "Any process that modulates the frequency, rate or extent of calcium ion export across the plasma membrane.") -AnnotationAssertion( "rph") -AnnotationAssertion( "2017-02-07T13:20:39Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of calcium ion efflux from cell") -AnnotationAssertion( "regulation of calcium ion export from cell") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905912") -AnnotationAssertion(rdfs:label "regulation of calcium ion export across plasma membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of calcium ion export across plasma membrane) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_miRNA") Annotation( "GOC:TermGenie") Annotation( "GOC:rph") Annotation( "GO_REF:0000058") Annotation( "PMID:22362515") "Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion export across the plasma membrane.") -AnnotationAssertion( "rph") -AnnotationAssertion( "2017-02-07T13:20:48Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of calcium ion efflux from cell") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of calcium ion export from cell") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of calcium ion efflux from cell") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of calcium ion export from cell") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of calcium ion efflux from cell") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of calcium ion export from cell") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of calcium ion efflux from cell") -AnnotationAssertion( "negative regulation of calcium ion export from cell") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of calcium ion efflux from cell") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of calcium ion export from cell") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905913") -AnnotationAssertion(rdfs:label "negative regulation of calcium ion export across plasma membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of calcium ion export across plasma membrane) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_miRNA") Annotation( "GOC:TermGenie") Annotation( "GOC:rph") Annotation( "GO_REF:0000058") Annotation( "PMID:22362515") "Any process that activates or increases the frequency, rate or extent of calcium ion export across the plasma membrane.") -AnnotationAssertion( "rph") -AnnotationAssertion( "2017-02-07T13:20:56Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of calcium ion efflux from cell") -AnnotationAssertion( "positive regulation of calcium ion export from cell") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of calcium ion efflux from cell") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of calcium ion export from cell") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of calcium ion efflux from cell") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of calcium ion export from cell") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of calcium ion efflux from cell") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of calcium ion export from cell") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of calcium ion efflux from cell") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of calcium ion export from cell") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905914") -AnnotationAssertion(rdfs:label "positive regulation of calcium ion export across plasma membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of acetylcholine biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:aruk") Annotation( "GOC:bc") Annotation( "GO_REF:0000058") Annotation( "PMID:20164328") "Any process that modulates the frequency, rate or extent of acetylcholine biosynthetic process.") -AnnotationAssertion( "bc") -AnnotationAssertion( "2017-02-08T13:08:30Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of acetylcholine anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of acetylcholine biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of acetylcholine formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of acetylcholine synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905921") -AnnotationAssertion(rdfs:label "regulation of acetylcholine biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of acetylcholine biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:aruk") Annotation( "GOC:bc") Annotation( "GO_REF:0000058") Annotation( "PMID:20164328") "Any process that stops, prevents or reduces the frequency, rate or extent of acetylcholine biosynthetic process.") -AnnotationAssertion( "bc") -AnnotationAssertion( "2017-02-08T13:08:39Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of acetylcholine anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of acetylcholine biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of acetylcholine biosynthetic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of acetylcholine formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of acetylcholine synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of acetylcholine anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of acetylcholine biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of acetylcholine biosynthetic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of acetylcholine formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of acetylcholine synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of acetylcholine anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of acetylcholine biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of acetylcholine biosynthetic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of acetylcholine formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of acetylcholine synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of acetylcholine anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of acetylcholine biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of acetylcholine formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of acetylcholine synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of acetylcholine anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of acetylcholine biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of acetylcholine biosynthetic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of acetylcholine formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of acetylcholine synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905922") -AnnotationAssertion(rdfs:label "negative regulation of acetylcholine biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of acetylcholine biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:aruk") Annotation( "GOC:bc") Annotation( "GO_REF:0000058") Annotation( "PMID:20164328") "Any process that activates or increases the frequency, rate or extent of acetylcholine biosynthetic process.") -AnnotationAssertion( "bc") -AnnotationAssertion( "2017-02-08T13:08:48Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of acetylcholine anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of acetylcholine biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of acetylcholine formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of acetylcholine synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of acetylcholine anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of acetylcholine biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of acetylcholine biosynthetic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of acetylcholine formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of acetylcholine synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of acetylcholine anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of acetylcholine biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of acetylcholine biosynthetic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of acetylcholine formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of acetylcholine synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of acetylcholine anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of acetylcholine biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of acetylcholine biosynthetic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of acetylcholine formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of acetylcholine synthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of acetylcholine anabolism") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of acetylcholine biosynthesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of acetylcholine biosynthetic process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of acetylcholine formation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of acetylcholine synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905923") -AnnotationAssertion(rdfs:label "positive regulation of acetylcholine biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of germ cell proliferation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:15342467") "Any process that modulates the frequency, rate or extent of germ cell proliferation.") -AnnotationAssertion( "hbye") -AnnotationAssertion( "2017-02-09T14:51:31Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905936") -AnnotationAssertion(rdfs:label "regulation of germ cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (negative regulation of germ cell proliferation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:15342467") "Any process that stops, prevents or reduces the frequency, rate or extent of germ cell proliferation.") -AnnotationAssertion( "hbye") -AnnotationAssertion( "2017-02-09T14:51:41Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of germ cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of germ cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of germ cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of germ cell proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905937") -AnnotationAssertion(rdfs:label "negative regulation of germ cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of germ cell proliferation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:15342467") "Any process that activates or increases the frequency, rate or extent of germ cell proliferation.") -AnnotationAssertion( "hbye") -AnnotationAssertion( "2017-02-09T14:51:51Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of germ cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of germ cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of germ cell proliferation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of germ cell proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905938") -AnnotationAssertion(rdfs:label "positive regulation of germ cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (regulation of gonad development) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:15342467") "Any process that modulates the frequency, rate or extent of gonad development.") -AnnotationAssertion( "hbye") -AnnotationAssertion( "2017-02-09T17:01:50Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of gonadogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905939") -AnnotationAssertion(rdfs:label "regulation of gonad development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of gonad development) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:15342467") "Any process that stops, prevents or reduces the frequency, rate or extent of gonad development.") -AnnotationAssertion( "hbye") -AnnotationAssertion( "2017-02-09T17:01:59Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of gonad development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of gonadogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of gonad development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of gonadogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of gonad development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of gonadogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of gonadogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of gonad development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of gonadogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905940") -AnnotationAssertion(rdfs:label "negative regulation of gonad development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of gonad development) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:15342467") "Any process that activates or increases the frequency, rate or extent of gonad development.") -AnnotationAssertion( "hbye") -AnnotationAssertion( "2017-02-09T17:02:08Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of gonadogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of gonad development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of gonadogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of gonad development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of gonadogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of gonad development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of gonadogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of gonad development") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of gonadogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905941") -AnnotationAssertion(rdfs:label "positive regulation of gonad development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (regulation of response to calcium ion) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:aruk") Annotation( "GOC:bc") Annotation( "GO_REF:0000058") Annotation( "PMID:11404397") "Any process that modulates the frequency, rate or extent of response to calcium ion.") -AnnotationAssertion( "bc") -AnnotationAssertion( "2017-02-13T10:56:34Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of response to Ca2+ ion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905945") -AnnotationAssertion(rdfs:label "regulation of response to calcium ion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of response to calcium ion) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:aruk") Annotation( "GOC:bc") Annotation( "GO_REF:0000058") Annotation( "PMID:11404397") "Any process that stops, prevents or reduces the frequency, rate or extent of response to calcium ion.") -AnnotationAssertion( "bc") -AnnotationAssertion( "2017-02-13T10:56:41Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of response to Ca2+ ion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of response to calcium ion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of response to Ca2+ ion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of response to calcium ion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of response to Ca2+ ion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of response to calcium ion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of response to Ca2+ ion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of response to Ca2+ ion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of response to calcium ion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905946") -AnnotationAssertion(rdfs:label "negative regulation of response to calcium ion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of response to calcium ion) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:aruk") Annotation( "GOC:bc") Annotation( "GO_REF:0000058") Annotation( "PMID:11404397") "Any process that activates or increases the frequency, rate or extent of response to calcium ion.") -AnnotationAssertion( "bc") -AnnotationAssertion( "2017-02-13T10:56:49Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of response to Ca2+ ion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of response to Ca2+ ion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of response to calcium ion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of response to Ca2+ ion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of response to calcium ion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of response to Ca2+ ion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of response to calcium ion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of response to Ca2+ ion") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of response to calcium ion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905947") -AnnotationAssertion(rdfs:label "positive regulation of response to calcium ion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of calcium ion import across plasma membrane) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:bhm") Annotation( "GO_REF:0000058") Annotation( "PMID:17640527") "Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion import across plasma membrane.") -AnnotationAssertion( "bhm") -AnnotationAssertion( "2017-02-17T09:42:30Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of calcium ion import across plasma membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of calcium ion import across plasma membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of calcium ion import across plasma membrane") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of calcium ion import across plasma membrane") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905949") -AnnotationAssertion(rdfs:comment "An example of this is PPP3CA in human (Q08209) in PMID:17640527 (inferred from direct assay).") -AnnotationAssertion(rdfs:label "negative regulation of calcium ion import across plasma membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of lipid localization) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:17564681") "Any process that modulates the frequency, rate or extent of lipid localization.") -AnnotationAssertion( "rz") -AnnotationAssertion( "2017-02-21T12:12:22Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of lipid localisation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905952") -AnnotationAssertion(rdfs:label "regulation of lipid localization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of lipid localization) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:17564681") "Any process that stops, prevents or reduces the frequency, rate or extent of lipid localization.") -AnnotationAssertion( "rz") -AnnotationAssertion( "2017-02-21T12:12:41Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of lipid localisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of lipid localization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of lipid localisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of lipid localization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of lipid localisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of lipid localization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of lipid localisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of lipid localisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of lipid localization") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905953") -AnnotationAssertion(rdfs:label "negative regulation of lipid localization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of lipid localization) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:17564681") "Any process that activates or increases the frequency, rate or extent of lipid localization.") -AnnotationAssertion( "rz") -AnnotationAssertion( "2017-02-21T12:12:49Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of lipid localisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of lipid localisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of lipid localization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of lipid localisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of lipid localization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of lipid localisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of lipid localization") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of lipid localisation") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of lipid localization") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905954") -AnnotationAssertion(rdfs:label "positive regulation of lipid localization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of endothelial tube morphogenesis) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_miRNA") Annotation( "GOC:TermGenie") Annotation( "GOC:rph") Annotation( "GO_REF:0000058") Annotation( "PMID:25961718") "Any process that stops, prevents or reduces the frequency, rate or extent of endothelial tube morphogenesis.") -AnnotationAssertion( "rph") -AnnotationAssertion( "2017-02-21T15:17:31Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of endothelial tube morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of endothelial tube morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of endothelial tube morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of endothelial tube morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905955") -AnnotationAssertion(rdfs:label "negative regulation of endothelial tube morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of endothelial tube morphogenesis) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_miRNA") Annotation( "GOC:TermGenie") Annotation( "GOC:rph") Annotation( "GO_REF:0000058") Annotation( "PMID:25961718") "Any process that activates or increases the frequency, rate or extent of endothelial tube morphogenesis.") -AnnotationAssertion( "rph") -AnnotationAssertion( "2017-02-21T15:17:39Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of endothelial tube morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of endothelial tube morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of endothelial tube morphogenesis") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of endothelial tube morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905956") -AnnotationAssertion(rdfs:label "positive regulation of endothelial tube morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (regulation of cellular response to alcohol) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:26434723") "Any process that modulates the frequency, rate or extent of cellular response to alcohol.") -AnnotationAssertion( "hbye") -AnnotationAssertion( "2017-02-22T12:03:00Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905957") -AnnotationAssertion(rdfs:label "regulation of cellular response to alcohol") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of cellular response to alcohol) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:26434723") "Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to alcohol.") -AnnotationAssertion( "hbye") -AnnotationAssertion( "2017-02-22T12:03:08Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of cellular response to alcohol") -AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of cellular response to alcohol") -AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of cellular response to alcohol") -AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of cellular response to alcohol") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905958") -AnnotationAssertion(rdfs:label "negative regulation of cellular response to alcohol") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of cellular response to alcohol) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:26434723") "Any process that activates or increases the frequency, rate or extent of cellular response to alcohol.") -AnnotationAssertion( "hbye") -AnnotationAssertion( "2017-02-22T12:03:16Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of cellular response to alcohol") -AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of cellular response to alcohol") -AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of cellular response to alcohol") -AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of cellular response to alcohol") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905959") -AnnotationAssertion(rdfs:label "positive regulation of cellular response to alcohol") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (glutamatergic neuron differentiation) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000086") Annotation( "PMID:24030726") "The process in which a relatively unspecialized cell acquires the specialized features of a glutamatergic neuron.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2017-02-23T17:40:43Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1905962") -AnnotationAssertion(rdfs:label "glutamatergic neuron differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (retinal cell apoptotic process) - -AnnotationAssertion(Annotation( "GOC:mtg_apoptosis") Annotation( "PMID:15558487") Annotation( "PMID:24664675") "Any apoptotic process in a retinal cell.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2012-12-12T10:15:08Z") -AnnotationAssertion( "GO:0046674") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "induction of retinal programmed cell death") -AnnotationAssertion( "GO:1990009") -AnnotationAssertion(rdfs:label "retinal cell apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (compound eye retinal cell apoptotic process) - -AnnotationAssertion(Annotation( "GOC:mtg_apoptosis") Annotation( "PMID:12021768") "Any apoptotic process in a compound eye retinal cell.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2012-12-12T10:21:07Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1990010") -AnnotationAssertion(rdfs:label "compound eye retinal cell apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (calcium ion export across plasma membrane) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "PMID:2145281") "The directed movement of calcium ions from inside of a cell, across the plasma membrane and into the extracellular region.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2013-02-07T13:01:29Z") -AnnotationAssertion(Annotation( "GOC:vw") Annotation( "PMID:2145281") "calcium ion efflux from cell") -AnnotationAssertion( "calcium ion export from cell") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1990034") -AnnotationAssertion(rdfs:label "calcium ion export across plasma membrane") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (anterograde neuronal dense core vesicle transport) - -AnnotationAssertion(Annotation( "GOC:kmv") Annotation( "PMID:23358451") "The directed movement of substances in neuronal dense core vesicles along axonal microtubules towards the presynapse.") -AnnotationAssertion( "anterograde dense core granule trafficking") -AnnotationAssertion( "anterograde dense core granule transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1990048") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "anterograde neuronal dense core vesicle transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (retrograde neuronal dense core vesicle transport) - -AnnotationAssertion(Annotation( "GOC:kmv") Annotation( "PMID:23358451") Annotation( "PMID:24762653") "The directed movement of neuronal dense core vesicles along axonal microtubules towards the cell body.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2013-02-19T13:31:44Z") -AnnotationAssertion( "retrograde dense core granule trafficking") -AnnotationAssertion( "retrograde dense core granule transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1990049") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "retrograde neuronal dense core vesicle transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) - -# Class: (lens fiber cell apoptotic process) - -AnnotationAssertion(Annotation( "CL:0011004") Annotation( "GOC:hjd") Annotation( "PMID:11095619") "Any apoptotic process in a lens fiber cell. Lens fiber cells are elongated, tightly packed cells that make up the bulk of the mature lens in a camera-type eye.") -AnnotationAssertion( "hjd") -AnnotationAssertion( "2013-05-01T19:09:28Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1990086") -AnnotationAssertion(rdfs:label "lens fiber cell apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (exosomal secretion) - -AnnotationAssertion(Annotation( "GOC:hjd") Annotation( "PMID:10572093") Annotation( "PMID:12154376") Annotation( "PMID:16773132") Annotation( "PMID:18617898") "The process whereby a membrane-bounded vesicle is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane.") -AnnotationAssertion( ) -AnnotationAssertion( "hjd") -AnnotationAssertion( "2013-09-04T21:08:14Z") -AnnotationAssertion(Annotation( "PMID:18617898") "exosomal secretory pathway") -AnnotationAssertion(Annotation( "GOC:hjd") "extracellular vesicular exosome secretion") -AnnotationAssertion( "multi-vesicular body fusion with plasma membrane") -AnnotationAssertion(Annotation( "PMID:18617898") "secretion of exosome") -AnnotationAssertion(Annotation( "PMID:18617898") "exosomal protein secretion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1990182") -AnnotationAssertion(rdfs:label "exosomal secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) -DisjointClasses( ObjectSomeValuesFrom( )) - -# Class: (euchromatin binding) - -AnnotationAssertion(Annotation( "GOC:vw") Annotation( "PMID:22431512") "Binding to euchromatin, a dispersed and relatively uncompacted form of chromatin.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2013-09-11T19:18:38Z") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:1990188") -AnnotationAssertion(rdfs:label "euchromatin binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (transferase complex) - -AnnotationAssertion(Annotation( "GOC:bhm") Annotation( "PMID:16540464") "A protein complex capable of catalyzing the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor).") -AnnotationAssertion( "bhm") -AnnotationAssertion( "2013-11-12T13:20:12Z") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:1990234") -AnnotationAssertion(rdfs:label "transferase complex") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (steroid hormone binding) - -AnnotationAssertion(Annotation( "GOC:ln") "Binding to a steroid hormone.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2013-11-15T09:26:18Z") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:1990239") -AnnotationAssertion(rdfs:label "steroid hormone binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (keratin filament binding) - -AnnotationAssertion(Annotation( "GOC:krc") Annotation( "PMID:6170061") "Binding to a keratin filament, an intermediate filament composed of acidic and basic keratins (types I and II), typically expressed in epithelial cells.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2013-12-13T22:05:25Z") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:1990254") -AnnotationAssertion(rdfs:label "keratin filament binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (neutrophil migration) - -AnnotationAssertion(Annotation( "PMID:1826836") "The movement of a neutrophil within or between different tissues and organs of the body.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2014-01-10T00:17:47Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1990266") -AnnotationAssertion(rdfs:label "neutrophil migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (RNA localization to chromatin) - -AnnotationAssertion(Annotation( "GOC:dos") Annotation( "GOC:mah") Annotation( "PMID:22582262") "A process in which RNA is transported to and maintained in a part of a chromosome that is organized into chromatin.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2014-01-30T15:55:34Z") -AnnotationAssertion( "RNA localisation to chromatin") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1990280") -AnnotationAssertion(rdfs:label "RNA localization to chromatin") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (transporter complex) - -AnnotationAssertion(Annotation( "GOC:bhm") Annotation( "PMID:15449578") "A protein complex facilitating transport of molecules (proteins, small molecules, nucleic acids) into, out of or within a cell, or between cells.") -AnnotationAssertion( "bhm") -AnnotationAssertion( "2014-03-26T14:23:27Z") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:1990351") -AnnotationAssertion(rdfs:comment "An example of this is GTR1 in human (UniProt symbol P11166) in PMID:15449578 (inferred from direct assay).") -AnnotationAssertion(rdfs:label "transporter complex") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (baculum development) - -AnnotationAssertion(Annotation( "GOC:sl") Annotation( "PMID:21471296") "The reproductive developmental process whose specific outcome is the progression of the baculum over time, from its formation to the mature structure.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2014-05-01T23:59:13Z") -AnnotationAssertion(Annotation( "GOC:sl") "os penis development") -AnnotationAssertion(Annotation( "GOC:sl") "penile bone development") -AnnotationAssertion(Annotation( "GOC:sl") "penis bone development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1990375") -AnnotationAssertion(rdfs:label "baculum development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (lipid transport across blood-brain barrier) - -AnnotationAssertion(Annotation( "GOC:sjp") Annotation( "PMID:24345162") "The directed movement of lipid molecules passing through the blood-brain barrier.") -AnnotationAssertion( "sjp") -AnnotationAssertion( "2014-05-08T09:52:28Z") -AnnotationAssertion( "lipid transport across blood brain barrier") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1990379") -AnnotationAssertion(rdfs:label "lipid transport across blood-brain barrier") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - -# Class: (detoxification of iron ion) - -AnnotationAssertion(Annotation( "GOC:sart") Annotation( "PMID:23064556") "Any process that reduces or removes the toxicity of iron ion. These include transport of iron away from sensitive areas and to compartments or complexes whose purpose is sequestration of iron ion.") -AnnotationAssertion( "sart") -AnnotationAssertion( "2014-08-19T10:12:46Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1990461") -AnnotationAssertion(rdfs:label "detoxification of iron ion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (dense core granule maturation) - -AnnotationAssertion(Annotation( "GOC:kmv") Annotation( "PMID:22654674") "Steps required to transform a dense core granule generated at the trans-Golgi network into a fully formed and transmissible dense core granule. Dense core granule maturation proceeds through clathrin-mediated membrane remodeling events and is essential for efficient processing of cargo within dense core granules as well as for removing factors that might otherwise interfere with dense core granule trafficking and exocytosis.") -AnnotationAssertion( "kmv") -AnnotationAssertion( "2014-09-30T20:35:11Z") -AnnotationAssertion( "dense core vesicle maturation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1990502") -AnnotationAssertion(rdfs:label "dense core granule maturation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of cytoplasmic translational termination) - -AnnotationAssertion(Annotation( "PMID:11570975") "Any process that modulates the frequency, rate or extent of cytoplasmic translational termination.") -AnnotationAssertion( "vw") -AnnotationAssertion( "2014-12-10T15:48:55Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1990580") -AnnotationAssertion(rdfs:label "regulation of cytoplasmic translational termination") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (sebum secreting cell proliferation) - -AnnotationAssertion(Annotation( "GOC:hjd") Annotation( "PMID:16901790") Annotation( "PMID:18474083") "The multiplication or reproduction of sebocytes by cell division, resulting in the expansion of their population. A sebocyte is an epithelial cell that makes up the sebaceous glands, and secrete sebum.") -AnnotationAssertion( "hjd") -AnnotationAssertion( "2015-02-23T19:43:49Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:dph") "sebocyte proliferation") -AnnotationAssertion( "GO:1990654") -AnnotationAssertion(rdfs:label "sebum secreting cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (cholangiocyte proliferation) - -AnnotationAssertion(Annotation( "PMID:24434010") "The multiplication or reproduction of cholangiocytes, resulting in the expansion of the cholangiocyte population. A cholangiocyte is an epithelial cell that is part of the bile duct. Cholangiocytes contribute to bile secretion via net release of bicarbonate and water.") -AnnotationAssertion( "2015-03-16T23:23:50Z") -AnnotationAssertion( "hepatoblast proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1990705") -AnnotationAssertion(rdfs:label "cholangiocyte proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (granulosa cell proliferation) - -AnnotationAssertion(Annotation( "PMID:22383759") "The multiplication or reproduction of granulosa cells, resulting in the expansion of the granulosa cells population. A granulosa cell is a supporting cell for the developing female gamete in the ovary of mammals. They develop from the coelomic epithelial cells of the gonadal ridge.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-05-06T18:56:04Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1990739") -AnnotationAssertion(rdfs:label "granulosa cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (cellular detoxification) - -AnnotationAssertion(Annotation( "GOC:vw") "Any process carried out at the cellular level that reduces or removes the toxicity of a toxic substance. These may include transport of the toxic substance away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance.") -AnnotationAssertion( "vw") -AnnotationAssertion( "2015-05-18T16:17:46Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1990748") -AnnotationAssertion(rdfs:label "cellular detoxification") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (Schwann cell chemotaxis) - -AnnotationAssertion(Annotation( "PMID:16203995") "The directed movement of a Schwann cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-05-21T19:19:09Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1990751") -AnnotationAssertion(rdfs:label "Schwann cell chemotaxis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (colon smooth muscle contraction) - -AnnotationAssertion(Annotation( "PMID:24170253") "A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry of the large intestine, exclusive of the rectum. The colon is that part of the large intestine that connects the small intestine to the rectum.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-06-10T18:29:21Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1990765") -AnnotationAssertion(rdfs:label "colon smooth muscle contraction") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - -# Class: (gastric mucosal blood circulation) - -AnnotationAssertion(Annotation( "PMID:10807413") "The flow of blood through the gastric mucosa of an animal, enabling the transport of nutrients and the removal of waste products.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-06-10T20:11:09Z") -AnnotationAssertion( "stomach mucosal blood circulation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1990768") -AnnotationAssertion(rdfs:label "gastric mucosal blood circulation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (small intestine smooth muscle contraction) - -AnnotationAssertion(Annotation( "PMID:11991626") "A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry in the intestine between the stomach and the large intestine.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-06-11T18:02:33Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1990770") -AnnotationAssertion(rdfs:label "small intestine smooth muscle contraction") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - -# Class: (protein localization to cell periphery) - -AnnotationAssertion(Annotation( "PMID:18216290") "A process in which a protein is transported to, or maintained in, the cell periphery.") -AnnotationAssertion( "2015-06-18T22:37:39Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1990778") -AnnotationAssertion(rdfs:label "protein localization to cell periphery") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (dorsal root ganglion development) - -AnnotationAssertion(Annotation( "PMID:18583150") "The process whose specific outcome is the progression of a dorsal root ganglion over time, from its formation to the mature structure.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-07-02T22:09:54Z") -AnnotationAssertion( "DRG development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1990791") -AnnotationAssertion(rdfs:label "dorsal root ganglion development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - # Class: (adaptive thermogenesis) AnnotationAssertion(Annotation( "PMID:17260010") Annotation( "PMID:20363363") "The regulated production of heat in response to short term environmental changes, such as stress, diet or reduced temperature.") @@ -133996,175 +28126,6 @@ AnnotationAssertion( "adaptive thermogenesis") SubClassOf( ) -# Class: (vacuolar localization) - -AnnotationAssertion(Annotation( "PMID:26283797") "Any process in which the vacuole is transported to, and/or maintained in, a specific location within the cell.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/22182"^^xsd:anyURI) -AnnotationAssertion( "mcc") -AnnotationAssertion( "2015-09-10T08:16:02Z") -AnnotationAssertion( "maintenance of vacuolar localization") -AnnotationAssertion( "maintenance of vacuole localization") -AnnotationAssertion( "maintenance of vacuole location") -AnnotationAssertion( "maintenance of vacuolar location") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1990849") -AnnotationAssertion(rdfs:label "vacuolar localization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (acinar cell proliferation) - -AnnotationAssertion(Annotation( "PMID:9788538") "The multiplication or reproduction of acinar cells, resulting in the expansion of a cell population. An acinar cell is a secretory cell that is grouped together with other cells of the same type to form grape-shaped clusters known as acini (singular acinus).") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-09-25T14:26:09Z") -AnnotationAssertion( "acinic cell proliferation") -AnnotationAssertion( "acinous cell proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1990863") -AnnotationAssertion(rdfs:label "acinar cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (vascular associated smooth muscle cell proliferation) - -AnnotationAssertion(Annotation( "PMID:23246467") "The multiplication or reproduction of vascular smooth muscle cells, resulting in the expansion of a cell population. A vascular smooth muscle cell is a non-striated, elongated, spindle-shaped cell found lining the blood vessels.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-09-29T16:34:59Z") -AnnotationAssertion( "VSMC proliferation") -AnnotationAssertion( "vascular smooth muscle cell proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1990874") -AnnotationAssertion(rdfs:label "vascular associated smooth muscle cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (ribonucleoprotein complex) - -AnnotationAssertion(Annotation( "GOC:krc") Annotation( "GOC:vesicles") "A macromolecular complex that contains both RNA and protein molecules.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2015-11-19T12:26:37Z") -AnnotationAssertion( "GO:0030529") -AnnotationAssertion( "GO:1990903") -AnnotationAssertion( "Wikipedia:Ribonucleoprotein") -AnnotationAssertion( "RNA-protein complex") -AnnotationAssertion( "RNP") -AnnotationAssertion( "protein-RNA complex") -AnnotationAssertion( "extracellular ribonucleoprotein complex") -AnnotationAssertion( "intracellular ribonucleoprotein complex") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:1990904") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "ribonucleoprotein complex") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (ooplasm) - -AnnotationAssertion(Annotation( "PMID:19022436") "The cytoplasm of an ovum.") -AnnotationAssertion( ) -AnnotationAssertion( "sl") -AnnotationAssertion( "2015-12-10T21:40:16Z") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:1990917") -AnnotationAssertion(rdfs:label "ooplasm") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) -DisjointClasses( ObjectSomeValuesFrom( )) - -# Class: (hepatic stellate cell proliferation) - -AnnotationAssertion(Annotation( "GOC:sl") Annotation( "PMID:15358192") Annotation( "PMID:18466260") "The multiplication or reproduction of hepatic stellate cells, resulting in the expansion of a hepatic stellate cell population. Hepatic stellate cells are found in the perisinusoidal space of the liver, and are capable of multiple roles including storage of retinol, presentation of antigen to T cells (including CD1d-restricted NKT cells), and upon activation, production of extracellular matrix components. This cell type comprises approximately 8-15% of total cells in the liver.") -AnnotationAssertion( "sl") -AnnotationAssertion( "2016-01-13T23:12:57Z") -AnnotationAssertion( "Ito cell proliferation") -AnnotationAssertion( "hepatic perisinusoidal cell proliferation") -AnnotationAssertion( "perisinusoidal cell proliferation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:1990922") -AnnotationAssertion(rdfs:label "hepatic stellate cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of metanephric S-shaped body morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") Annotation( "GOC:obol") Annotation( "GOC:yaf") "Any process that modulates the frequency, rate or extent of metanephric S-shaped body morphogenesis.") -AnnotationAssertion( "jl") -AnnotationAssertion( "2010-07-30T02:14:33Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000004") -AnnotationAssertion(rdfs:label "regulation of metanephric S-shaped body morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (negative regulation of metanephric S-shaped body morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") Annotation( "GOC:obol") Annotation( "GOC:yaf") "Any process that stops, prevents, or reduces the frequency, rate or extent of metanephric S-shaped body morphogenesis.") -AnnotationAssertion( "jl") -AnnotationAssertion( "2010-07-30T02:14:37Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000005") -AnnotationAssertion(rdfs:label "negative regulation of metanephric S-shaped body morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of metanephric comma-shaped body morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") Annotation( "GOC:obol") Annotation( "GOC:yaf") "Any process that modulates the frequency, rate or extent of metanephric comma-shaped body morphogenesis.") -AnnotationAssertion( "jl") -AnnotationAssertion( "2010-07-30T02:17:12Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000006") -AnnotationAssertion(rdfs:label "regulation of metanephric comma-shaped body morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (negative regulation of metanephric comma-shaped body morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") Annotation( "GOC:obol") Annotation( "GOC:yaf") "Any process that stops, prevents, or reduces the frequency, rate or extent of metanephric comma-shaped body morphogenesis.") -AnnotationAssertion( "jl") -AnnotationAssertion( "2010-07-30T02:17:17Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000007") -AnnotationAssertion(rdfs:label "negative regulation of metanephric comma-shaped body morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of male gonad development) - -AnnotationAssertion(Annotation( "GOC:obol") Annotation( "GOC:yaf") "Any process that modulates the frequency, rate or extent of male gonad development.") -AnnotationAssertion( "jl") -AnnotationAssertion( "2010-07-15T03:29:05Z") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of testicular development") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of testis development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000018") -AnnotationAssertion(rdfs:label "regulation of male gonad development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of male gonad development) - -AnnotationAssertion(Annotation( "GOC:obol") Annotation( "GOC:yaf") "Any process that stops, prevents, or reduces the frequency, rate or extent of male gonad development.") -AnnotationAssertion( "jl") -AnnotationAssertion( "2010-07-15T03:29:10Z") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of testicular development") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of testis development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000019") -AnnotationAssertion(rdfs:label "negative regulation of male gonad development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of male gonad development) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of male gonad development.") -AnnotationAssertion( "jl") -AnnotationAssertion( "2010-07-15T03:29:13Z") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of testicular development") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of testis development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000020") -AnnotationAssertion(rdfs:label "positive regulation of male gonad development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (regulation of multicellular organismal development) AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of multicellular organismal development.") @@ -134173,88 +28134,9 @@ AnnotationAssertion( AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:2000026") AnnotationAssertion(rdfs:label "regulation of multicellular organismal development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) -# Class: (regulation of animal organ morphogenesis) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of animal organ morphogenesis.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2010-08-05T11:26:27Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of histogenesis and organogenesis") -AnnotationAssertion( "GO:2000027") -AnnotationAssertion(rdfs:label "regulation of animal organ morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of stem cell division) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of stem cell division.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2010-08-05T11:34:53Z") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of stem cell renewal") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000035") -AnnotationAssertion(rdfs:label "regulation of stem cell division") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of stem cell population maintenance) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of stem cell population maintenance.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2010-08-05T11:35:25Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of maintenance of pluripotency") -AnnotationAssertion( "GO:2000036") -AnnotationAssertion(rdfs:label "regulation of stem cell population maintenance") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of ureter smooth muscle cell differentiation) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") Annotation( "GOC:obol") Annotation( "GOC:yaf") "Any process that modulates the frequency, rate or extent of ureter smooth muscle cell differentiation.") -AnnotationAssertion( "jl") -AnnotationAssertion( "2010-08-20T01:44:16Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000061") -AnnotationAssertion(rdfs:label "regulation of ureter smooth muscle cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (negative regulation of ureter smooth muscle cell differentiation) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") Annotation( "GOC:obol") Annotation( "GOC:yaf") "Any process that stops, prevents, or reduces the frequency, rate or extent of ureter smooth muscle cell differentiation.") -AnnotationAssertion( "jl") -AnnotationAssertion( "2010-08-20T01:44:23Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000062") -AnnotationAssertion(rdfs:label "negative regulation of ureter smooth muscle cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of ureter smooth muscle cell differentiation) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") Annotation( "GOC:obol") Annotation( "GOC:yaf") "Any process that activates or increases the frequency, rate or extent of ureter smooth muscle cell differentiation.") -AnnotationAssertion( "jl") -AnnotationAssertion( "2010-08-20T01:44:28Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000063") -AnnotationAssertion(rdfs:label "positive regulation of ureter smooth muscle cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (regulation of defense response to insect) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of defense response to insect.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2010-08-23T09:30:00Z") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of physiological defense response to insect") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000068") -AnnotationAssertion(rdfs:label "regulation of defense response to insect") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (regulation of response to water deprivation) AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of response to water deprivation.") @@ -134267,246 +28149,8 @@ AnnotationAssertion( "GOC:obol") "regulation of drought tolerance") AnnotationAssertion( "GO:2000070") AnnotationAssertion(rdfs:label "regulation of response to water deprivation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (regulation of type B pancreatic cell development) - -AnnotationAssertion(Annotation( "GOC:obol") Annotation( "GOC:yaf") "Any process that modulates the frequency, rate or extent of pancreatic B cell development.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2010-08-27T11:19:37Z") -AnnotationAssertion(Annotation( "GOC:mah") "regulation of pancreatic B cell development") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of pancreatic beta cell development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000074") -AnnotationAssertion(rdfs:label "regulation of type B pancreatic cell development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of type B pancreatic cell development) - -AnnotationAssertion(Annotation( "GOC:obol") Annotation( "GOC:yaf") "Any process that stops, prevents, or reduces the frequency, rate or extent of pancreatic B cell development.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2010-08-27T11:21:17Z") -AnnotationAssertion(Annotation( "GOC:mah") "negative regulation of pancreatic B cell development") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of pancreatic beta cell development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000077") -AnnotationAssertion(rdfs:label "negative regulation of type B pancreatic cell development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of type B pancreatic cell development) - -AnnotationAssertion(Annotation( "GOC:obol") Annotation( "GOC:yaf") "Any process that activates or increases the frequency, rate or extent of pancreatic B cell development.") -AnnotationAssertion( "tb") -AnnotationAssertion( "2010-08-27T11:21:19Z") -AnnotationAssertion(Annotation( "GOC:mah") "positive regulation of pancreatic B cell development") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of pancreatic beta cell development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000078") -AnnotationAssertion(rdfs:label "positive regulation of type B pancreatic cell development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "Any process that modulates the frequency, rate or extent of mesenchymal to epithelial transition involved in mesonephros morphogenesis.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-09-03T06:06:41Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of mesonephric mesenchyme to epithelial transition") -AnnotationAssertion( "GO:2000084") -AnnotationAssertion(rdfs:label "regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "Any process that stops, prevents, or reduces the frequency, rate or extent of mesenchymal to epithelial transition involved in mesonephros morphogenesis.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-09-03T06:08:21Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of mesonephric mesenchyme to epithelial transition") -AnnotationAssertion( "GO:2000085") -AnnotationAssertion(rdfs:label "negative regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "Any process that activates or increases the frequency, rate or extent of mesenchymal to epithelial transition involved in mesonephros morphogenesis.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-09-03T06:08:24Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of mesonephric mesenchyme to epithelial transition") -AnnotationAssertion( "GO:2000086") -AnnotationAssertion(rdfs:label "positive regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of mesonephric glomerulus development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "Any process that modulates the frequency, rate or extent of mesonephric glomerulus development.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-09-03T06:09:19Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000087") -AnnotationAssertion(rdfs:label "regulation of mesonephric glomerulus development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (negative regulation of mesonephric glomerulus development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "Any process that stops, prevents, or reduces the frequency, rate or extent of mesonephric glomerulus development.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-09-03T06:09:22Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000088") -AnnotationAssertion(rdfs:label "negative regulation of mesonephric glomerulus development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of mesonephric glomerulus development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "Any process that activates or increases the frequency, rate or extent of mesonephric glomerulus development.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-09-03T06:09:24Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000089") -AnnotationAssertion(rdfs:label "positive regulation of mesonephric glomerulus development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of mesonephric nephron tubule epithelial cell differentiation) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "Any process that modulates the frequency, rate or extent of mesonephric nephron tubule epithelial cell differentiation.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-09-03T06:12:25Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000093") -AnnotationAssertion(rdfs:label "regulation of mesonephric nephron tubule epithelial cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of mesonephric nephron tubule epithelial cell differentiation) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "Any process that stops, prevents, or reduces the frequency, rate or extent of mesonephric nephron tubule epithelial cell differentiation.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-09-03T06:12:28Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000094") -AnnotationAssertion(rdfs:label "negative regulation of mesonephric nephron tubule epithelial cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of leukocyte apoptotic process) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mtg_apoptosis") "Any process that modulates the frequency, rate or extent of leukocyte apoptotic process.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-09-15T01:42:05Z") -AnnotationAssertion( "regulation of leukocyte apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000106") -AnnotationAssertion(rdfs:label "regulation of leukocyte apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of leukocyte apoptotic process) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mtg_apoptosis") "Any process that stops, prevents, or reduces the frequency, rate or extent of leukocyte apoptotic process.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-09-15T01:42:09Z") -AnnotationAssertion( "negative regulation of leukocyte apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000107") -AnnotationAssertion(rdfs:label "negative regulation of leukocyte apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of leukocyte apoptotic process) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mtg_apoptosis") "Any process that activates or increases the frequency, rate or extent of leukocyte apoptotic process.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-09-15T01:42:12Z") -AnnotationAssertion( "positive regulation of leukocyte apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000108") -AnnotationAssertion(rdfs:label "positive regulation of leukocyte apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of macrophage apoptotic process) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mtg_apoptosis") "Any process that modulates the frequency, rate or extent of macrophage apoptotic process.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-09-15T01:44:15Z") -AnnotationAssertion( "regulation of macrophage apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:yaf") "regulation of AICD") -AnnotationAssertion(Annotation( "GOC:yaf") "regulation of activation-induced cell death") -AnnotationAssertion( "GO:2000109") -AnnotationAssertion(rdfs:label "regulation of macrophage apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of macrophage apoptotic process) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mtg_apoptosis") "Any process that stops, prevents, or reduces the frequency, rate or extent of macrophage apoptotic process.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-09-15T01:44:18Z") -AnnotationAssertion( "negative regulation of macrophage apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:yaf") "negative regulation of AICD") -AnnotationAssertion(Annotation( "GOC:yaf") "negative regulation of activation-induced cell death") -AnnotationAssertion( "GO:2000110") -AnnotationAssertion(rdfs:label "negative regulation of macrophage apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of macrophage apoptotic process) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mtg_apoptosis") "Any process that activates or increases the frequency, rate or extent of macrophage apoptotic process.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-09-15T01:44:21Z") -AnnotationAssertion( "positive regulation of macrophage apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:yaf") "positive regulation of AICD") -AnnotationAssertion(Annotation( "GOC:yaf") "positive regulation of activation-induced cell death") -AnnotationAssertion( "GO:2000111") -AnnotationAssertion(rdfs:label "positive regulation of macrophage apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of establishment of cell polarity) - -AnnotationAssertion(Annotation( "GOC:dph") "Any process that modulates the frequency, rate or extent of establishment of cell polarity.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-09-16T01:22:36Z") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of cell polarization") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of bud site selection/establishment of cell polarity") -AnnotationAssertion( "GO:2000114") -AnnotationAssertion(rdfs:label "regulation of establishment of cell polarity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of cell proliferation involved in heart morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") "Any process that modulates the frequency, rate or extent of cell proliferation involved in heart morphogenesis.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-09-29T12:43:53Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000136") -AnnotationAssertion(rdfs:label "regulation of cell proliferation involved in heart morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of cell proliferation involved in heart morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") "Any process that stops, prevents, or reduces the frequency, rate or extent of cell proliferation involved in heart morphogenesis.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-09-29T12:43:55Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000137") -AnnotationAssertion(rdfs:label "negative regulation of cell proliferation involved in heart morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of cell proliferation involved in heart morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") "Any process that activates or increases the frequency, rate or extent of cell proliferation involved in heart morphogenesis.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-09-29T12:43:57Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000138") -AnnotationAssertion(rdfs:label "positive regulation of cell proliferation involved in heart morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (regulation of cell motility) AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of cell motility.") @@ -134518,23 +28162,8 @@ AnnotationAssertion( "GOC:obol") "regulation of cell movement") AnnotationAssertion( "GO:2000145") AnnotationAssertion(rdfs:label "regulation of cell motility") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (negative regulation of cell motility) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of cell motility.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-10-01T09:41:26Z") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of cell locomotion") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of movement of a cell") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of cell movement") -AnnotationAssertion( "GO:2000146") -AnnotationAssertion(rdfs:label "negative regulation of cell motility") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - # Class: (positive regulation of cell motility) AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of cell motility.") @@ -134546,3126 +28175,8 @@ AnnotationAssertion( "GOC:obol") "positive regulation of cell movement") AnnotationAssertion( "GO:2000147") AnnotationAssertion(rdfs:label "positive regulation of cell motility") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (positive regulation of cilium-dependent cell motility) - -AnnotationAssertion(Annotation( "GOC:cilia") Annotation( "GOC:jl") "Any process that activates or increases the frequency, rate or extent of cilium-dependent cell motility.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-10-04T12:41:05Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "positive regulation of ciliary cell motility") -AnnotationAssertion( "GO:2000155") -AnnotationAssertion(rdfs:label "positive regulation of cilium-dependent cell motility") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of dendrite development) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents, or reduces the frequency, rate or extent of dendrite development.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2010-10-07T10:53:15Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000171") -AnnotationAssertion(rdfs:label "negative regulation of dendrite development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of branching morphogenesis of a nerve) - -AnnotationAssertion(Annotation( "GOC:BHF") "Any process that modulates the frequency, rate or extent of branching morphogenesis of a nerve.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2010-10-07T12:07:54Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000172") -AnnotationAssertion(rdfs:label "regulation of branching morphogenesis of a nerve") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of branching morphogenesis of a nerve) - -AnnotationAssertion(Annotation( "GOC:BHF") "Any process that stops, prevents, or reduces the frequency, rate or extent of branching morphogenesis of a nerve.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2010-10-07T12:07:56Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000173") -AnnotationAssertion(rdfs:label "negative regulation of branching morphogenesis of a nerve") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of pro-T cell differentiation) - -AnnotationAssertion(Annotation( "GOC:BHF") "Any process that modulates the frequency, rate or extent of pro-T cell differentiation.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-10-11T10:24:30Z") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of pro-T lymphocyte differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000174") -AnnotationAssertion(rdfs:label "regulation of pro-T cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (negative regulation of pro-T cell differentiation) - -AnnotationAssertion(Annotation( "GOC:BHF") "Any process that stops, prevents, or reduces the frequency, rate or extent of pro-T cell differentiation.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-10-11T10:24:33Z") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of pro-T lymphocyte differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000175") -AnnotationAssertion(rdfs:label "negative regulation of pro-T cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of pro-T cell differentiation) - -AnnotationAssertion(Annotation( "GOC:BHF") "Any process that activates or increases the frequency, rate or extent of pro-T cell differentiation.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-10-11T10:24:35Z") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of pro-T lymphocyte differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000176") -AnnotationAssertion(rdfs:label "positive regulation of pro-T cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (regulation of neural precursor cell proliferation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:yaf") "Any process that modulates the frequency, rate or extent of neural precursor cell proliferation.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-10-13T12:40:41Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000177") -AnnotationAssertion(rdfs:label "regulation of neural precursor cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of neural precursor cell proliferation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:yaf") "Any process that stops, prevents, or reduces the frequency, rate or extent of neural precursor cell proliferation.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-10-13T12:40:43Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000178") -AnnotationAssertion(rdfs:label "negative regulation of neural precursor cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of neural precursor cell proliferation) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:yaf") "Any process that activates or increases the frequency, rate or extent of neural precursor cell proliferation.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-10-13T12:40:45Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000179") -AnnotationAssertion(rdfs:label "positive regulation of neural precursor cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of blood vessel morphogenesis) - -AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:yaf") "Any process that stops, prevents, or reduces the frequency, rate or extent of blood vessel morphogenesis.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-10-13T12:46:31Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000181") -AnnotationAssertion(rdfs:label "negative regulation of blood vessel morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of progesterone biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:dph") "Any process that modulates the frequency, rate or extent of progesterone biosynthetic process.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-10-14T07:36:06Z") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of progesterone anabolism") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of progesterone biosynthesis") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of progesterone formation") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of progesterone synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000182") -AnnotationAssertion(rdfs:label "regulation of progesterone biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of progesterone biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:dph") "Any process that stops, prevents, or reduces the frequency, rate or extent of progesterone biosynthetic process.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-10-14T07:36:10Z") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of progesterone anabolism") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of progesterone biosynthesis") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of progesterone formation") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of progesterone synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000183") -AnnotationAssertion(rdfs:label "negative regulation of progesterone biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of progesterone biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:dph") "Any process that activates or increases the frequency, rate or extent of progesterone biosynthetic process.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-10-14T07:36:14Z") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of progesterone anabolism") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of progesterone biosynthesis") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of progesterone formation") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of progesterone synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000184") -AnnotationAssertion(rdfs:label "positive regulation of progesterone biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of phosphate transmembrane transport) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of phosphate transmembrane transport.") -AnnotationAssertion( "vw") -AnnotationAssertion( "2010-10-15T11:33:04Z") -AnnotationAssertion( "regulation of phosphate membrane transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000185") -AnnotationAssertion(rdfs:label "regulation of phosphate transmembrane transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of phosphate transmembrane transport) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents, or reduces the frequency, rate or extent of phosphate transmembrane transport.") -AnnotationAssertion( "vw") -AnnotationAssertion( "2010-10-15T11:33:08Z") -AnnotationAssertion( "negative regulation of phosphate membrane transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000186") -AnnotationAssertion(rdfs:label "negative regulation of phosphate transmembrane transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of phosphate transmembrane transport) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of phosphate transmembrane transport.") -AnnotationAssertion( "vw") -AnnotationAssertion( "2010-10-15T11:33:10Z") -AnnotationAssertion( "positive regulation of phosphate membrane transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000187") -AnnotationAssertion(rdfs:label "positive regulation of phosphate transmembrane transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of fatty acid transport) - -AnnotationAssertion(Annotation( "GOC:BHF") "Any process that modulates the frequency, rate or extent of fatty acid transport.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2010-10-18T10:37:13Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000191") -AnnotationAssertion(rdfs:label "regulation of fatty acid transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of fatty acid transport) - -AnnotationAssertion(Annotation( "GOC:BHF") "Any process that stops, prevents, or reduces the frequency, rate or extent of fatty acid transport.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2010-10-18T10:37:15Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000192") -AnnotationAssertion(rdfs:label "negative regulation of fatty acid transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of fatty acid transport) - -AnnotationAssertion(Annotation( "GOC:BHF") "Any process that activates or increases the frequency, rate or extent of fatty acid transport.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2010-10-18T10:37:17Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000193") -AnnotationAssertion(rdfs:label "positive regulation of fatty acid transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of female gonad development) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of female gonad development.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2010-10-19T10:45:34Z") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of ovarian development") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of ovary development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000194") -AnnotationAssertion(rdfs:label "regulation of female gonad development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of female gonad development) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents, or reduces the frequency, rate or extent of female gonad development.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2010-10-19T10:45:38Z") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of ovarian development") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of ovary development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000195") -AnnotationAssertion(rdfs:label "negative regulation of female gonad development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of female gonad development) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of female gonad development.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2010-10-19T10:45:41Z") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of ovarian development") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of ovary development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000196") -AnnotationAssertion(rdfs:label "positive regulation of female gonad development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of glutamate metabolic process) - -AnnotationAssertion(Annotation( "GOC:sl") "Any process that modulates the frequency, rate or extent of glutamate metabolic process.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-11-03T02:43:51Z") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of glutamate metabolism") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of glutamic acid metabolic process") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of glutamic acid metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000211") -AnnotationAssertion(rdfs:label "regulation of glutamate metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (negative regulation of glutamate metabolic process) - -AnnotationAssertion(Annotation( "GOC:sl") "Any process that stops, prevents, or reduces the frequency, rate or extent of glutamate metabolic process.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-11-03T02:43:55Z") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of glutamate metabolism") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of glutamic acid metabolic process") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of glutamic acid metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000212") -AnnotationAssertion(rdfs:label "negative regulation of glutamate metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of glutamate metabolic process) - -AnnotationAssertion(Annotation( "GOC:sl") "Any process that activates or increases the frequency, rate or extent of glutamate metabolic process.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-11-03T02:43:59Z") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of glutamate metabolism") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of glutamic acid metabolic process") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of glutamic acid metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000213") -AnnotationAssertion(rdfs:label "positive regulation of glutamate metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of testosterone biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:obol") Annotation( "GOC:yaf") "Any process that modulates the frequency, rate or extent of testosterone biosynthetic process.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2010-11-09T10:38:33Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000224") -AnnotationAssertion(rdfs:label "regulation of testosterone biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of testosterone biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:obol") Annotation( "GOC:yaf") "Any process that stops, prevents, or reduces the frequency, rate or extent of testosterone biosynthetic process.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2010-11-09T10:38:37Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000225") -AnnotationAssertion(rdfs:label "negative regulation of testosterone biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of pancreatic A cell differentiation) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of pancreatic A cell differentiation.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-11-09T03:43:37Z") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of pancreatic alpha cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000226") -AnnotationAssertion(rdfs:label "regulation of pancreatic A cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of pancreatic A cell differentiation) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of pancreatic A cell differentiation.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-11-09T03:43:40Z") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of pancreatic alpha cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000227") -AnnotationAssertion(rdfs:label "negative regulation of pancreatic A cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of pancreatic A cell differentiation) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of pancreatic A cell differentiation.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-11-09T03:43:42Z") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of pancreatic alpha cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000228") -AnnotationAssertion(rdfs:label "positive regulation of pancreatic A cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (regulation of reproductive process) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of reproductive process.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-11-10T02:44:02Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000241") -AnnotationAssertion(rdfs:label "regulation of reproductive process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (negative regulation of reproductive process) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of reproductive process.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-11-10T02:44:05Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000242") -AnnotationAssertion(rdfs:label "negative regulation of reproductive process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of reproductive process) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of reproductive process.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-11-10T02:44:08Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000243") -AnnotationAssertion(rdfs:label "positive regulation of reproductive process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of establishment or maintenance of neuroblast polarity) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents, or reduces the frequency, rate or extent of establishment or maintenance of neuroblast polarity.") -AnnotationAssertion( "vw") -AnnotationAssertion( "2010-11-11T11:40:34Z") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of establishment and/or maintenance of neuroblast cell polarity") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000248") -AnnotationAssertion(rdfs:label "negative regulation of establishment or maintenance of neuroblast polarity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (negative regulation of feeding behavior) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of feeding behavior.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2010-11-18T11:24:14Z") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of behavioral response to food") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of behavioural response to food") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of feeding behaviour") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of drinking") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of eating") -AnnotationAssertion( "GO:2000252") -AnnotationAssertion(rdfs:label "negative regulation of feeding behavior") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of feeding behavior) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of feeding behavior.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2010-11-18T11:24:18Z") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of behavioral response to food") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of behavioural response to food") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of feeding behaviour") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of drinking") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of eating") -AnnotationAssertion( "GO:2000253") -AnnotationAssertion(rdfs:label "positive regulation of feeding behavior") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of male germ cell proliferation) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of male germ cell proliferation.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-11-18T09:29:44Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000254") -AnnotationAssertion(rdfs:label "regulation of male germ cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of male germ cell proliferation) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of male germ cell proliferation.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-11-18T09:29:47Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000255") -AnnotationAssertion(rdfs:label "negative regulation of male germ cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (positive regulation of male germ cell proliferation) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of male germ cell proliferation.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2010-11-18T09:29:50Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000256") -AnnotationAssertion(rdfs:label "positive regulation of male germ cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of fibroblast apoptotic process) - -AnnotationAssertion(Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:obol") Annotation( "GOC:yaf") "Any process that modulates the frequency, rate or extent of fibroblast apoptotic process.") -AnnotationAssertion( "jl") -AnnotationAssertion( "2010-11-23T01:07:23Z") -AnnotationAssertion( "regulation of fibroblast apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000269") -AnnotationAssertion(rdfs:label "regulation of fibroblast apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of fibroblast apoptotic process) - -AnnotationAssertion(Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:obol") Annotation( "GOC:yaf") "Any process that stops, prevents or reduces the frequency, rate or extent of fibroblast apoptotic process.") -AnnotationAssertion( "jl") -AnnotationAssertion( "2010-11-23T01:07:27Z") -AnnotationAssertion( "negative regulation of fibroblast apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000270") -AnnotationAssertion(rdfs:label "negative regulation of fibroblast apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of fibroblast apoptotic process) - -AnnotationAssertion(Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:obol") Annotation( "GOC:yaf") "Any process that activates or increases the frequency, rate or extent of fibroblast apoptotic process.") -AnnotationAssertion( "jl") -AnnotationAssertion( "2010-11-23T01:07:29Z") -AnnotationAssertion( "positive regulation of fibroblast apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000271") -AnnotationAssertion(rdfs:label "positive regulation of fibroblast apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of signaling receptor activity) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of a signaling receptor activity.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2010-12-02T09:28:47Z") -AnnotationAssertion( "negative regulation of receptor activity") -AnnotationAssertion( "negative regulation of signalling receptor activity") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000272") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "negative regulation of signaling receptor activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of signaling receptor activity) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of signaling receptor activity.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2010-12-02T09:28:50Z") -AnnotationAssertion( "positive regulation of signalling receptor activity") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000273") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "positive regulation of signaling receptor activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of DNA biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of DNA biosynthetic process.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2010-12-08T04:48:15Z") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of DNA anabolism") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of DNA biosynthesis") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of DNA formation") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of DNA synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000278") -AnnotationAssertion(rdfs:label "regulation of DNA biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of DNA biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of DNA biosynthetic process.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2010-12-08T04:48:20Z") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of DNA anabolism") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of DNA biosynthesis") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of DNA formation") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of DNA synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000279") -AnnotationAssertion(rdfs:label "negative regulation of DNA biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of cellular amino acid biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of cellular amino acid biosynthetic process.") -AnnotationAssertion( "vw") -AnnotationAssertion( "2010-12-10T11:54:19Z") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of amino acid biosynthetic process") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of cellular amino acid anabolism") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of cellular amino acid biosynthesis") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of cellular amino acid formation") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of cellular amino acid synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000282") -AnnotationAssertion(rdfs:label "regulation of cellular amino acid biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of amino acid biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of an amino acid biosynthetic process.") -AnnotationAssertion( "vw") -AnnotationAssertion( "2010-12-10T11:54:23Z") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of amino acid anabolism") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of amino acid biosynthesis") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of amino acid formation") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of amino acid synthesis") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of cellular amino acid biosynthetic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000283") -AnnotationAssertion(rdfs:label "negative regulation of amino acid biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of amino acid biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of cellular amino acid biosynthetic process.") -AnnotationAssertion( "vw") -AnnotationAssertion( "2010-12-10T11:54:27Z") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of amino acid anabolism") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of amino acid biosynthesis") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of amino acid formation") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of amino acid synthesis") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of cellular amino acid biosynthetic process") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000284") -AnnotationAssertion(rdfs:label "positive regulation of amino acid biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of myotome development) - -AnnotationAssertion(Annotation( "GOC:BHF") "Any process that activates or increases the frequency, rate or extent of myotome development.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2010-12-16T05:17:15Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000287") -AnnotationAssertion(rdfs:label "positive regulation of myotome development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of myoblast proliferation) - -AnnotationAssertion(Annotation( "GOC:BHF") "Any process that activates or increases the frequency, rate or extent of myoblast proliferation.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2010-12-16T05:20:52Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000288") -AnnotationAssertion(rdfs:label "positive regulation of myoblast proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of myotome development) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of myotome development.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-12-20T10:22:05Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000290") -AnnotationAssertion(rdfs:label "regulation of myotome development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of myoblast proliferation) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of myoblast proliferation.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2010-12-20T10:34:26Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000291") -AnnotationAssertion(rdfs:label "regulation of myoblast proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of defecation) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of defecation.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2010-12-21T09:23:08Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000292") -AnnotationAssertion(rdfs:label "regulation of defecation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (negative regulation of defecation) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of defecation.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2010-12-21T09:23:13Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000293") -AnnotationAssertion(rdfs:label "negative regulation of defecation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of defecation) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of defecation.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2010-12-21T09:23:16Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000294") -AnnotationAssertion(rdfs:label "positive regulation of defecation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of synaptic vesicle exocytosis) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of synaptic vesicle exocytosis.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2011-01-03T08:20:40Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000300") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "regulation of synaptic vesicle exocytosis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (negative regulation of synaptic vesicle exocytosis) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle exocytosis.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2011-01-03T08:21:00Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000301") -AnnotationAssertion(rdfs:label "negative regulation of synaptic vesicle exocytosis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of synaptic vesicle exocytosis) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of synaptic vesicle exocytosis.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2011-01-03T08:21:14Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000302") -AnnotationAssertion(rdfs:label "positive regulation of synaptic vesicle exocytosis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (regulation of ceramide biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:dph") "Any process that modulates the frequency, rate or extent of a ceramide biosynthetic process.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2011-01-04T02:37:12Z") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of ceramide anabolism") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of ceramide biosynthesis") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of ceramide formation") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of ceramide synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000303") -AnnotationAssertion(rdfs:label "regulation of ceramide biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of ceramide biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:dph") "Any process that activates or increases the frequency, rate or extent of ceramide biosynthetic process.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2011-01-04T02:37:32Z") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of ceramide anabolism") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of ceramide biosynthesis") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of ceramide formation") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of ceramide synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000304") -AnnotationAssertion(rdfs:label "positive regulation of ceramide biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of glucocorticoid receptor signaling pathway) - -AnnotationAssertion(Annotation( "GOC:BHF") "Any process that modulates the frequency, rate or extent of glucocorticoid receptor signaling pathway.") -AnnotationAssertion( "vk") -AnnotationAssertion( "2011-01-18T04:38:10Z") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of glucocorticoid receptor signalling pathway") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000322") -AnnotationAssertion(rdfs:label "regulation of glucocorticoid receptor signaling pathway") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of glucocorticoid receptor signaling pathway) - -AnnotationAssertion(Annotation( "GOC:BHF") "Any process that stops, prevents or reduces the frequency, rate or extent of glucocorticoid receptor signaling pathway.") -AnnotationAssertion( "vk") -AnnotationAssertion( "2011-01-18T04:38:43Z") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of glucocorticoid receptor signalling pathway") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000323") -AnnotationAssertion(rdfs:label "negative regulation of glucocorticoid receptor signaling pathway") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of glucocorticoid receptor signaling pathway) - -AnnotationAssertion(Annotation( "GOC:BHF") "Any process that activates or increases the frequency, rate or extent of glucocorticoid receptor signaling pathway.") -AnnotationAssertion( "vk") -AnnotationAssertion( "2011-01-18T04:39:05Z") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of glucocorticoid receptor signalling pathway") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000324") -AnnotationAssertion(rdfs:label "positive regulation of glucocorticoid receptor signaling pathway") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of endothelial cell apoptotic process) - -AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:mtg_apoptosis") "Any process that modulates the frequency, rate or extent of endothelial cell apoptotic process.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2011-02-03T10:43:16Z") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of apoptosis of endothelial cells") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of endothelial cell programmed cell death by apoptosis") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of killing of endothelial cells") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of programmed cell death of endothelial cells by apoptosis") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of programmed cell death, endothelial cells") -AnnotationAssertion( "regulation of endothelial cell apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000351") -AnnotationAssertion(rdfs:label "regulation of endothelial cell apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of endothelial cell apoptotic process) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mah") Annotation( "GOC:mtg_apoptosis") "Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell apoptotic process.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2011-02-03T10:43:20Z") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of apoptosis of endothelial cells") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of endothelial cell programmed cell death by apoptosis") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of killing of endothelial cells") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of programmed cell death of endothelial cells by apoptosis") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of programmed cell death, endothelial cells") -AnnotationAssertion( "negative regulation of endothelial cell apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000352") -AnnotationAssertion(rdfs:label "negative regulation of endothelial cell apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of endothelial cell apoptotic process) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mah") Annotation( "GOC:mtg_apoptosis") "Any process that activates or increases the frequency, rate or extent of endothelial cell apoptotic process.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2011-02-03T10:43:23Z") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of apoptosis of endothelial cells") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of endothelial cell programmed cell death by apoptosis") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of killing of endothelial cells") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of programmed cell death of endothelial cells by apoptosis") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of programmed cell death, endothelial cells") -AnnotationAssertion( "positive regulation of endothelial cell apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000353") -AnnotationAssertion(rdfs:label "positive regulation of endothelial cell apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of ovarian follicle development) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of ovarian follicle development.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2011-02-03T02:01:28Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of follicular phase") -AnnotationAssertion( "GO:2000354") -AnnotationAssertion(rdfs:label "regulation of ovarian follicle development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of ovarian follicle development) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of ovarian follicle development.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2011-02-03T02:01:32Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of follicular phase") -AnnotationAssertion( "GO:2000355") -AnnotationAssertion(rdfs:label "negative regulation of ovarian follicle development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of oxygen metabolic process) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of oxygen metabolic process.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2011-02-11T02:03:32Z") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of diatomic oxygen metabolic process") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of oxygen metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000374") -AnnotationAssertion(rdfs:label "regulation of oxygen metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of oxygen metabolic process) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents or reduces the frequency, rate or extent of oxygen metabolic process.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2011-02-11T02:03:44Z") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of diatomic oxygen metabolic process") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of oxygen metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000375") -AnnotationAssertion(rdfs:label "negative regulation of oxygen metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of oxygen metabolic process) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of oxygen metabolic process.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2011-02-11T02:03:52Z") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of diatomic oxygen metabolic process") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of oxygen metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000376") -AnnotationAssertion(rdfs:label "positive regulation of oxygen metabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of mesoderm development) - -AnnotationAssertion(Annotation( "GOC:BHF") "Any process that modulates the frequency, rate or extent of mesoderm development.") -AnnotationAssertion( "vk") -AnnotationAssertion( "2011-02-15T03:09:46Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000380") -AnnotationAssertion(rdfs:label "regulation of mesoderm development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (negative regulation of mesoderm development) - -AnnotationAssertion(Annotation( "GOC:BHF") "Any process that stops, prevents or reduces the frequency, rate or extent of mesoderm development.") -AnnotationAssertion( "vk") -AnnotationAssertion( "2011-02-15T03:10:02Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000381") -AnnotationAssertion(rdfs:label "negative regulation of mesoderm development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of mesoderm development) - -AnnotationAssertion(Annotation( "GOC:BHF") "Any process that activates or increases the frequency, rate or extent of mesoderm development.") -AnnotationAssertion( "vk") -AnnotationAssertion( "2011-02-15T03:10:12Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000382") -AnnotationAssertion(rdfs:label "positive regulation of mesoderm development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of ectoderm development) - -AnnotationAssertion(Annotation( "GOC:BHF") "Any process that modulates the frequency, rate or extent of ectoderm development.") -AnnotationAssertion( "vk") -AnnotationAssertion( "2011-02-15T03:17:10Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000383") -AnnotationAssertion(rdfs:label "regulation of ectoderm development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (negative regulation of ectoderm development) - -AnnotationAssertion(Annotation( "GOC:BHF") "Any process that stops, prevents or reduces the frequency, rate or extent of ectoderm development.") -AnnotationAssertion( "vk") -AnnotationAssertion( "2011-02-15T03:17:27Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000384") -AnnotationAssertion(rdfs:label "negative regulation of ectoderm development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of ectoderm development) - -AnnotationAssertion(Annotation( "GOC:BHF") "Any process that activates or increases the frequency, rate or extent of ectoderm development.") -AnnotationAssertion( "vk") -AnnotationAssertion( "2011-02-15T03:17:39Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000385") -AnnotationAssertion(rdfs:label "positive regulation of ectoderm development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of ovarian follicle development) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of ovarian follicle development.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2011-02-16T02:21:21Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of follicular phase") -AnnotationAssertion( "GO:2000386") -AnnotationAssertion(rdfs:label "positive regulation of ovarian follicle development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of antral ovarian follicle growth) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of antral ovarian follicle growth.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2011-02-16T04:53:43Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000387") -AnnotationAssertion(rdfs:label "regulation of antral ovarian follicle growth") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of antral ovarian follicle growth) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of antral ovarian follicle growth.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2011-02-16T04:54:01Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000388") -AnnotationAssertion(rdfs:label "positive regulation of antral ovarian follicle growth") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of lymphocyte migration) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of lymphocyte migration.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2011-02-23T10:45:19Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000401") -AnnotationAssertion(rdfs:label "regulation of lymphocyte migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of lymphocyte migration) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents or reduces the frequency, rate or extent of lymphocyte migration.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2011-02-23T10:45:47Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000402") -AnnotationAssertion(rdfs:label "negative regulation of lymphocyte migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of lymphocyte migration) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of lymphocyte migration.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2011-02-23T10:46:06Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000403") -AnnotationAssertion(rdfs:label "positive regulation of lymphocyte migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of T cell migration) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of T cell migration.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2011-02-23T10:48:24Z") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of T lymphocyte migration") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of T-cell migration") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of T-lymphocyte migration") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000404") -AnnotationAssertion(rdfs:label "regulation of T cell migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of T cell migration) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents or reduces the frequency, rate or extent of T cell migration.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2011-02-23T10:48:52Z") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of T lymphocyte migration") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of T-cell migration") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of T-lymphocyte migration") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000405") -AnnotationAssertion(rdfs:label "negative regulation of T cell migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of T cell migration) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of T cell migration.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2011-02-23T10:49:12Z") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of T lymphocyte migration") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of T-cell migration") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of T-lymphocyte migration") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000406") -AnnotationAssertion(rdfs:label "positive regulation of T cell migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of thymocyte migration) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of thymocyte migration.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2011-02-23T01:33:32Z") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of thymic lymphocyte migration") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of immature T cell migration") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of immature T lymphocyte migration") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of immature T-cell migration") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of immature T-lymphocyte migration") -AnnotationAssertion( "GO:2000410") -AnnotationAssertion(rdfs:label "regulation of thymocyte migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of thymocyte migration) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents or reduces the frequency, rate or extent of thymocyte migration.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2011-02-23T01:34:01Z") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of thymic lymphocyte migration") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of immature T cell migration") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of immature T lymphocyte migration") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of immature T-cell migration") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of immature T-lymphocyte migration") -AnnotationAssertion( "GO:2000411") -AnnotationAssertion(rdfs:label "negative regulation of thymocyte migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of thymocyte migration) - -AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of thymocyte migration.") -AnnotationAssertion( "mah") -AnnotationAssertion( "2011-02-23T01:34:23Z") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of thymic lymphocyte migration") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of immature T cell migration") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of immature T lymphocyte migration") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of immature T-cell migration") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of immature T-lymphocyte migration") -AnnotationAssertion( "GO:2000412") -AnnotationAssertion(rdfs:label "positive regulation of thymocyte migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of astrocyte chemotaxis) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of astrocyte chemotaxis.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-03-04T10:53:50Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000458") -AnnotationAssertion(rdfs:label "regulation of astrocyte chemotaxis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of astrocyte chemotaxis) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of astrocyte chemotaxis.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-03-04T10:54:28Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000459") -AnnotationAssertion(rdfs:label "negative regulation of astrocyte chemotaxis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of excitatory postsynaptic potential) - -AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:bf") "Any process that enhances the establishment or increases the extent of the excitatory postsynaptic potential (EPSP) which is a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2011-03-04T02:43:32Z") -AnnotationAssertion( "positive regulation of excitatory post-synaptic membrane potential") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:obol") "positive regulation of EPSP") -AnnotationAssertion( "GO:2000463") -AnnotationAssertion(rdfs:label "positive regulation of excitatory postsynaptic potential") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of astrocyte chemotaxis) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of astrocyte chemotaxis.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-03-04T04:43:29Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000464") -AnnotationAssertion(rdfs:label "positive regulation of astrocyte chemotaxis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of hematopoietic stem cell migration) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of hematopoietic stem cell migration.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-03-09T09:34:08Z") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of hemopoietic stem cell migration") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000471") -AnnotationAssertion(rdfs:label "regulation of hematopoietic stem cell migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of hematopoietic stem cell migration) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic stem cell migration.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-03-09T09:34:54Z") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of hemopoietic stem cell migration") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000472") -AnnotationAssertion(rdfs:label "negative regulation of hematopoietic stem cell migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of hematopoietic stem cell migration) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of hematopoietic stem cell migration.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-03-09T09:35:25Z") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of hemopoietic stem cell migration") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000473") -AnnotationAssertion(rdfs:label "positive regulation of hematopoietic stem cell migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of metanephric podocyte development) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of metanephric glomerular visceral epithelial cell development.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/23000"^^xsd:anyURI) -AnnotationAssertion( "yaf") -AnnotationAssertion( "2011-03-09T05:16:40Z") -AnnotationAssertion( "regulation of metanephric glomerular visceral epithelial cell development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000477") -AnnotationAssertion(rdfs:label "regulation of metanephric podocyte development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of metanephric podocyte development) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of metanephric glomerular visceral epithelial cell development.") -AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/23000"^^xsd:anyURI) -AnnotationAssertion( "yaf") -AnnotationAssertion( "2011-03-09T05:17:26Z") -AnnotationAssertion( "positive regulation of metanephric glomerular visceral epithelial cell development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000478") -AnnotationAssertion(rdfs:label "positive regulation of metanephric podocyte development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of hepatic stellate cell activation) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of hepatic stellate cell activation.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-03-14T03:48:32Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000489") -AnnotationAssertion(rdfs:label "regulation of hepatic stellate cell activation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of hepatic stellate cell activation) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of hepatic stellate cell activation.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-03-14T03:49:18Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000490") -AnnotationAssertion(rdfs:label "negative regulation of hepatic stellate cell activation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of hepatic stellate cell activation) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of hepatic stellate cell activation.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-03-14T03:49:48Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000491") -AnnotationAssertion(rdfs:label "positive regulation of hepatic stellate cell activation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of cell proliferation involved in compound eye morphogenesis) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of cell proliferation involved in compound eye morphogenesis.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-03-18T02:18:34Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000495") -AnnotationAssertion(rdfs:label "regulation of cell proliferation involved in compound eye morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of cell proliferation involved in compound eye morphogenesis) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation involved in compound eye morphogenesis.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-03-18T02:19:22Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000496") -AnnotationAssertion(rdfs:label "negative regulation of cell proliferation involved in compound eye morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of cell proliferation involved in compound eye morphogenesis) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of cell proliferation involved in compound eye morphogenesis.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-03-18T02:19:54Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000497") -AnnotationAssertion(rdfs:label "positive regulation of cell proliferation involved in compound eye morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of dendritic cell chemotaxis) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of dendritic cell chemotaxis.") -AnnotationAssertion( "ebc") -AnnotationAssertion( "2011-03-22T10:21:38Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000508") -AnnotationAssertion(rdfs:label "regulation of dendritic cell chemotaxis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of dendritic cell chemotaxis) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell chemotaxis.") -AnnotationAssertion( "ebc") -AnnotationAssertion( "2011-03-22T10:21:45Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000509") -AnnotationAssertion(rdfs:label "negative regulation of dendritic cell chemotaxis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of dendritic cell chemotaxis) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of dendritic cell chemotaxis.") -AnnotationAssertion( "ebc") -AnnotationAssertion( "2011-03-22T10:21:49Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000510") -AnnotationAssertion(rdfs:label "positive regulation of dendritic cell chemotaxis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of myeloid dendritic cell chemotaxis) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of myeloid dendritic cell chemotaxis.") -AnnotationAssertion( "ebc") -AnnotationAssertion( "2011-03-23T12:18:32Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000527") -AnnotationAssertion(rdfs:label "regulation of myeloid dendritic cell chemotaxis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of myeloid dendritic cell chemotaxis) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of myeloid dendritic cell chemotaxis.") -AnnotationAssertion( "ebc") -AnnotationAssertion( "2011-03-23T12:18:39Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000528") -AnnotationAssertion(rdfs:label "negative regulation of myeloid dendritic cell chemotaxis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of myeloid dendritic cell chemotaxis) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of myeloid dendritic cell chemotaxis.") -AnnotationAssertion( "ebc") -AnnotationAssertion( "2011-03-23T12:18:45Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000529") -AnnotationAssertion(rdfs:label "positive regulation of myeloid dendritic cell chemotaxis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of B cell chemotaxis) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of B cell chemotaxis.") -AnnotationAssertion( "ebc") -AnnotationAssertion( "2011-03-29T09:49:25Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000537") -AnnotationAssertion(rdfs:label "regulation of B cell chemotaxis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of B cell chemotaxis) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of B cell chemotaxis.") -AnnotationAssertion( "ebc") -AnnotationAssertion( "2011-03-29T09:49:33Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000538") -AnnotationAssertion(rdfs:label "positive regulation of B cell chemotaxis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of gastrulation) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of gastrulation.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2011-04-01T04:10:08Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000542") -AnnotationAssertion(rdfs:label "negative regulation of gastrulation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of gastrulation) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of gastrulation.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2011-04-01T04:10:15Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000543") -AnnotationAssertion(rdfs:label "positive regulation of gastrulation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of dendritic cell dendrite assembly) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of dendritic cell dendrite assembly.") -AnnotationAssertion( "ebc") -AnnotationAssertion( "2011-04-03T07:21:55Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of dendritic extension") -AnnotationAssertion( "GO:2000547") -AnnotationAssertion(rdfs:label "regulation of dendritic cell dendrite assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of dendritic cell dendrite assembly) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell dendrite assembly.") -AnnotationAssertion( "ebc") -AnnotationAssertion( "2011-04-03T07:22:01Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of dendritic extension") -AnnotationAssertion( "GO:2000548") -AnnotationAssertion(rdfs:label "negative regulation of dendritic cell dendrite assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of dendritic cell dendrite assembly) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of dendritic cell dendrite assembly.") -AnnotationAssertion( "ebc") -AnnotationAssertion( "2011-04-03T07:22:06Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of dendritic extension") -AnnotationAssertion( "GO:2000549") -AnnotationAssertion(rdfs:label "positive regulation of dendritic cell dendrite assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of B cell chemotaxis) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of B cell chemotaxis.") -AnnotationAssertion( "ebc") -AnnotationAssertion( "2011-04-03T07:25:59Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000550") -AnnotationAssertion(rdfs:label "negative regulation of B cell chemotaxis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of DNA biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of DNA biosynthetic process.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2011-04-04T10:01:20Z") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of DNA anabolism") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of DNA biosynthesis") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of DNA formation") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of DNA synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000573") -AnnotationAssertion(rdfs:label "positive regulation of DNA biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of optic nerve formation) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of optic nerve formation.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2011-04-11T03:41:30Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of CN II biosynthesis") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of CN II formation") -AnnotationAssertion( "GO:2000595") -AnnotationAssertion(rdfs:label "regulation of optic nerve formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (negative regulation of optic nerve formation) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of optic nerve formation.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2011-04-11T03:41:35Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of CN II biosynthesis") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of CN II formation") -AnnotationAssertion( "GO:2000596") -AnnotationAssertion(rdfs:label "negative regulation of optic nerve formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of optic nerve formation) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of optic nerve formation.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2011-04-11T03:41:39Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of CN II biosynthesis") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of CN II formation") -AnnotationAssertion( "GO:2000597") -AnnotationAssertion(rdfs:label "positive regulation of optic nerve formation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of cell proliferation involved in mesonephros development) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of cell proliferation involved in mesonephros development.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2011-04-18T08:42:19Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000606") -AnnotationAssertion(rdfs:label "regulation of cell proliferation involved in mesonephros development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of cell proliferation involved in mesonephros development) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation involved in mesonephros development.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2011-04-18T08:42:23Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000607") -AnnotationAssertion(rdfs:label "negative regulation of cell proliferation involved in mesonephros development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of cell proliferation involved in mesonephros development) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of cell proliferation involved in mesonephros development.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2011-04-18T08:42:25Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000608") -AnnotationAssertion(rdfs:label "positive regulation of cell proliferation involved in mesonephros development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of thyroid hormone generation) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of thyroid hormone generation.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2011-04-18T10:12:14Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000609") -AnnotationAssertion(rdfs:label "regulation of thyroid hormone generation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of thyroid hormone generation) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of thyroid hormone generation.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2011-04-18T10:12:19Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000610") -AnnotationAssertion(rdfs:label "negative regulation of thyroid hormone generation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of thyroid hormone generation) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of thyroid hormone generation.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2011-04-18T10:12:22Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000611") -AnnotationAssertion(rdfs:label "positive regulation of thyroid hormone generation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of stem cell proliferation) - -AnnotationAssertion(Annotation( "GOC:dph") "Any process that stops, prevents or reduces the frequency, rate or extent of stem cell proliferation.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2011-04-27T01:04:22Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000647") -AnnotationAssertion(rdfs:label "negative regulation of stem cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of stem cell proliferation) - -AnnotationAssertion(Annotation( "GOC:dph") "Any process that activates or increases the frequency, rate or extent of stem cell proliferation.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2011-04-27T01:04:25Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000648") -AnnotationAssertion(rdfs:label "positive regulation of stem cell proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of sodium ion transmembrane transporter activity) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of sodium ion transmembrane transporter activity.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2011-04-28T08:42:53Z") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of sodium transporter activity") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000649") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "regulation of sodium ion transmembrane transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (negative regulation of sodium ion transmembrane transporter activity) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of sodium ion transmembrane transporter activity.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2011-04-28T08:42:57Z") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of sodium transporter activity") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000650") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "negative regulation of sodium ion transmembrane transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of sodium ion transmembrane transporter activity) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of sodium ion transmembrane transporter activity.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2011-04-28T08:43:00Z") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of sodium transporter activity") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000651") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "positive regulation of sodium ion transmembrane transporter activity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (regulation of cellular response to testosterone stimulus) - -AnnotationAssertion(Annotation( "GOC:BHF") "Any process that modulates the frequency, rate or extent of cellular response to testosterone stimulus.") -AnnotationAssertion( "vk") -AnnotationAssertion( "2011-05-02T03:23:56Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000654") -AnnotationAssertion(rdfs:label "regulation of cellular response to testosterone stimulus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of cellular response to testosterone stimulus) - -AnnotationAssertion(Annotation( "GOC:BHF") "Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to testosterone stimulus.") -AnnotationAssertion( "vk") -AnnotationAssertion( "2011-05-02T03:23:59Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000655") -AnnotationAssertion(rdfs:label "negative regulation of cellular response to testosterone stimulus") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of apolipoprotein binding) - -AnnotationAssertion(Annotation( "GOC:BHF") "Any process that modulates the frequency, rate or extent of apolipoprotein binding.") -AnnotationAssertion( "vk") -AnnotationAssertion( "2011-05-02T05:33:41Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000656") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "regulation of apolipoprotein binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of apolipoprotein binding) - -AnnotationAssertion(Annotation( "GOC:BHF") "Any process that stops, prevents or reduces the frequency, rate or extent of apolipoprotein binding.") -AnnotationAssertion( "vk") -AnnotationAssertion( "2011-05-02T05:33:44Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000657") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "negative regulation of apolipoprotein binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of apolipoprotein binding) - -AnnotationAssertion(Annotation( "GOC:BHF") "Any process that activates or increases the frequency, rate or extent of apolipoprotein binding.") -AnnotationAssertion( "vk") -AnnotationAssertion( "2011-05-02T05:33:46Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000658") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "positive regulation of apolipoprotein binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of dendritic cell apoptotic process) - -AnnotationAssertion(Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of dendritic cell apoptotic process.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2011-05-09T07:34:16Z") -AnnotationAssertion( "regulation of dendritic cell apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000668") -AnnotationAssertion(rdfs:label "regulation of dendritic cell apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of dendritic cell apoptotic process) - -AnnotationAssertion(Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell apoptotic process.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2011-05-09T07:34:21Z") -AnnotationAssertion( "negative regulation of dendritic cell apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000669") -AnnotationAssertion(rdfs:label "negative regulation of dendritic cell apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of dendritic cell apoptotic process) - -AnnotationAssertion(Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of dendritic cell apoptotic process.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2011-05-09T07:34:26Z") -AnnotationAssertion( "positive regulation of dendritic cell apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000670") -AnnotationAssertion(rdfs:label "positive regulation of dendritic cell apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of motor neuron apoptotic process) - -AnnotationAssertion(Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of motor neuron apoptotic process.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2011-05-09T10:56:17Z") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of motoneuron apoptosis") -AnnotationAssertion( "regulation of motor neuron apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000671") -AnnotationAssertion(rdfs:label "regulation of motor neuron apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of motor neuron apoptotic process) - -AnnotationAssertion(Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of motor neuron apoptotic process.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2011-05-09T10:56:21Z") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of motoneuron apoptosis") -AnnotationAssertion( "negative regulation of motor neuron apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000672") -AnnotationAssertion(rdfs:label "negative regulation of motor neuron apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of motor neuron apoptotic process) - -AnnotationAssertion(Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of motor neuron apoptotic process.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2011-05-09T10:56:24Z") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of motoneuron apoptosis") -AnnotationAssertion( "positive regulation of motor neuron apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000673") -AnnotationAssertion(rdfs:label "positive regulation of motor neuron apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of type B pancreatic cell apoptotic process) - -AnnotationAssertion(Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of type B pancreatic cell apoptotic process.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2011-05-09T11:51:09Z") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of pancreatic B cell apoptosis") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of pancreatic beta cell apoptosis") -AnnotationAssertion( "regulation of type B pancreatic cell apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000674") -AnnotationAssertion(rdfs:label "regulation of type B pancreatic cell apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of type B pancreatic cell apoptotic process) - -AnnotationAssertion(Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of type B pancreatic cell apoptotic process.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2011-05-09T11:51:12Z") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of pancreatic B cell apoptosis") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of pancreatic beta cell apoptosis") -AnnotationAssertion( "negative regulation of type B pancreatic cell apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000675") -AnnotationAssertion(rdfs:label "negative regulation of type B pancreatic cell apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of type B pancreatic cell apoptotic process) - -AnnotationAssertion(Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of type B pancreatic cell apoptotic process.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2011-05-09T11:51:15Z") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of pancreatic B cell apoptosis") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of pancreatic beta cell apoptosis") -AnnotationAssertion( "positive regulation of type B pancreatic cell apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000676") -AnnotationAssertion(rdfs:label "positive regulation of type B pancreatic cell apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of cardiac muscle cell myoblast differentiation) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of cardiac muscle cell myoblast differentiation.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2011-05-25T09:08:01Z") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of myocardial precursor cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of cardiac myoblast differentiation") -AnnotationAssertion( "GO:2000690") -AnnotationAssertion(rdfs:label "regulation of cardiac muscle cell myoblast differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of cardiac muscle cell myoblast differentiation) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of cardiac muscle cell myoblast differentiation.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2011-05-25T09:08:06Z") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of myocardial precursor cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of cardiac myoblast differentiation") -AnnotationAssertion( "GO:2000691") -AnnotationAssertion(rdfs:label "negative regulation of cardiac muscle cell myoblast differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of epithelial cell differentiation involved in kidney development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") Annotation( "GOC:yaf") "Any process that modulates the frequency, rate or extent of epithelial cell differentiation involved in kidney development.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-05-16T04:23:52Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000696") -AnnotationAssertion(rdfs:label "regulation of epithelial cell differentiation involved in kidney development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of epithelial cell differentiation involved in kidney development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") Annotation( "GOC:yaf") "Any process that stops, prevents or reduces the frequency, rate or extent of epithelial cell differentiation involved in kidney development.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-05-16T04:23:55Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000697") -AnnotationAssertion(rdfs:label "negative regulation of epithelial cell differentiation involved in kidney development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of epithelial cell differentiation involved in kidney development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") Annotation( "GOC:yaf") "Any process that activates or increases the frequency, rate or extent of epithelial cell differentiation involved in kidney development.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-05-16T04:23:57Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000698") -AnnotationAssertion(rdfs:label "positive regulation of epithelial cell differentiation involved in kidney development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of cardiac muscle cell myoblast differentiation) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of cardiac muscle cell myoblast differentiation.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2011-05-25T09:08:09Z") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of myocardial precursor cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of cardiac myoblast differentiation") -AnnotationAssertion( "GO:2000700") -AnnotationAssertion(rdfs:label "positive regulation of cardiac muscle cell myoblast differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of cardiac muscle cell differentiation) - -AnnotationAssertion(Annotation( "GOC:BHF") "Any process that modulates the frequency, rate or extent of cardiac muscle cell differentiation.") -AnnotationAssertion( "vk") -AnnotationAssertion( "2011-06-08T10:51:06Z") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of cardiomyocyte differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of heart muscle cell differentiation") -AnnotationAssertion( "GO:2000725") -AnnotationAssertion(rdfs:label "regulation of cardiac muscle cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of cardiac muscle cell differentiation) - -AnnotationAssertion(Annotation( "GOC:BHF") "Any process that stops, prevents or reduces the frequency, rate or extent of cardiac muscle cell differentiation.") -AnnotationAssertion( "vk") -AnnotationAssertion( "2011-06-08T10:51:11Z") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of cardiomyocyte differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of heart muscle cell differentiation") -AnnotationAssertion( "GO:2000726") -AnnotationAssertion(rdfs:label "negative regulation of cardiac muscle cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of cardiac muscle cell differentiation) - -AnnotationAssertion(Annotation( "GOC:BHF") "Any process that activates or increases the frequency, rate or extent of cardiac muscle cell differentiation.") -AnnotationAssertion( "vk") -AnnotationAssertion( "2011-06-08T10:51:15Z") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of cardiomyocyte differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of heart muscle cell differentiation") -AnnotationAssertion( "GO:2000727") -AnnotationAssertion(rdfs:label "positive regulation of cardiac muscle cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of mesenchymal cell proliferation involved in ureter development) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of mesenchymal cell proliferation involved in ureter development.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2011-06-10T02:27:19Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of ureter mesenchymal cell proliferation") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of ureteral mesenchymal cell proliferation") -AnnotationAssertion( "GO:2000729") -AnnotationAssertion(rdfs:label "positive regulation of mesenchymal cell proliferation involved in ureter development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (regulation of stem cell differentiation) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of stem cell differentiation.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2011-06-14T02:05:16Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000736") -AnnotationAssertion(rdfs:label "regulation of stem cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of stem cell differentiation) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of stem cell differentiation.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2011-06-14T02:05:20Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000737") -AnnotationAssertion(rdfs:label "negative regulation of stem cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of stem cell differentiation) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of stem cell differentiation.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2011-06-14T02:05:23Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000738") -AnnotationAssertion(rdfs:label "positive regulation of stem cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of cytoplasmic translation) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of cytoplasmic translation.") -AnnotationAssertion( "vw") -AnnotationAssertion( "2011-06-20T10:39:19Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000765") -AnnotationAssertion(rdfs:label "regulation of cytoplasmic translation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of cytoplasmic translation) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic translation.") -AnnotationAssertion( "vw") -AnnotationAssertion( "2011-06-20T10:39:23Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000766") -AnnotationAssertion(rdfs:label "negative regulation of cytoplasmic translation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of cytoplasmic translation) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of cytoplasmic translation.") -AnnotationAssertion( "vw") -AnnotationAssertion( "2011-06-20T10:39:26Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000767") -AnnotationAssertion(rdfs:label "positive regulation of cytoplasmic translation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of nephron tubule epithelial cell differentiation) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of nephron tubule epithelial cell differentiation.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2011-06-22T11:55:06Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000768") -AnnotationAssertion(rdfs:label "positive regulation of nephron tubule epithelial cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of mesenchymal cell proliferation involved in lung development) - -AnnotationAssertion(Annotation( "PMID:21513708") "Any process that modulates the frequency, rate or extent of mesenchymal cell proliferation involved in lung development.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2011-06-24T01:53:50Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000790") -AnnotationAssertion(rdfs:label "regulation of mesenchymal cell proliferation involved in lung development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of mesenchymal cell proliferation involved in lung development) - -AnnotationAssertion(Annotation( "PMID:21513708") "Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal cell proliferation involved in lung development.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2011-06-24T01:53:53Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000791") -AnnotationAssertion(rdfs:label "negative regulation of mesenchymal cell proliferation involved in lung development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of mesenchymal cell proliferation involved in lung development) - -AnnotationAssertion(Annotation( "PMID:21513708") "Any process that activates or increases the frequency, rate or extent of mesenchymal cell proliferation involved in lung development.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2011-06-24T01:53:56Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000792") -AnnotationAssertion(rdfs:label "positive regulation of mesenchymal cell proliferation involved in lung development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (cell proliferation involved in heart valve development) - -AnnotationAssertion(Annotation( "GOC:BHF") "Any cell proliferation that is involved in heart valve development.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-06-24T03:12:15Z") -AnnotationAssertion(Annotation( "GOC:obol") "cell proliferation of cardiac valve development") -AnnotationAssertion(Annotation( "GOC:obol") "cell proliferation of heart valve development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000793") -AnnotationAssertion(rdfs:label "cell proliferation involved in heart valve development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of epithelial cell proliferation involved in lung morphogenesis) - -AnnotationAssertion(Annotation( "PMID:21513708") "Any process that modulates the frequency, rate or extent of epithelial cell proliferation involved in lung morphogenesis.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2011-06-25T07:22:38Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000794") -AnnotationAssertion(rdfs:label "regulation of epithelial cell proliferation involved in lung morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of epithelial cell proliferation involved in lung morphogenesis) - -AnnotationAssertion(Annotation( "PMID:21513708") "Any process that stops, prevents or reduces the frequency, rate or extent of epithelial cell proliferation involved in lung morphogenesis.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2011-06-25T07:22:42Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000795") -AnnotationAssertion(rdfs:label "negative regulation of epithelial cell proliferation involved in lung morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of bicellular tight junction assembly) - -AnnotationAssertion(Annotation( "GOC:BHF") "Any process that modulates the frequency, rate or extent of tight junction assembly.") -AnnotationAssertion( "vk") -AnnotationAssertion( "2011-07-06T01:08:28Z") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of tight junction formation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000810") -AnnotationAssertion(rdfs:label "regulation of bicellular tight junction assembly") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of myoblast proliferation) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of myoblast proliferation.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2011-07-12T03:06:04Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000818") -AnnotationAssertion(rdfs:label "negative regulation of myoblast proliferation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of grooming behavior) - -AnnotationAssertion(Annotation( "GOC:BHF") "Any process that modulates the frequency, rate or extent of grooming behavior.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2011-07-14T04:48:12Z") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of grooming behaviour") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000821") -AnnotationAssertion(rdfs:label "regulation of grooming behavior") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (regulation of heart morphogenesis) - -AnnotationAssertion(Annotation( "GOC:BHF") "Any process that modulates the frequency, rate or extent of heart morphogenesis.") -AnnotationAssertion( "vk") -AnnotationAssertion( "2011-07-19T10:08:58Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of cardiac morphogenesis") -AnnotationAssertion( "GO:2000826") -AnnotationAssertion(rdfs:label "regulation of heart morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of parathyroid hormone secretion) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of parathyroid hormone secretion.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-07-26T08:37:53Z") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of PTH secretion") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of parathormone secretion") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of parathyrin secretion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000828") -AnnotationAssertion(rdfs:label "regulation of parathyroid hormone secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of parathyroid hormone secretion) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of parathyroid hormone secretion.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-07-26T08:37:57Z") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of PTH secretion") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of parathormone secretion") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of parathyrin secretion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000829") -AnnotationAssertion(rdfs:label "negative regulation of parathyroid hormone secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of parathyroid hormone secretion) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of parathyroid hormone secretion.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-07-26T08:38:00Z") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of PTH secretion") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of parathormone secretion") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of parathyrin secretion") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000830") -AnnotationAssertion(rdfs:label "positive regulation of parathyroid hormone secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of steroid hormone secretion) - -AnnotationAssertion(Annotation( "GOC:sl") "Any process that modulates the frequency, rate or extent of steroid hormone secretion.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-07-26T08:38:46Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000831") -AnnotationAssertion(rdfs:label "regulation of steroid hormone secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of steroid hormone secretion) - -AnnotationAssertion(Annotation( "GOC:sl") "Any process that stops, prevents or reduces the frequency, rate or extent of steroid hormone secretion.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-07-26T08:38:50Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000832") -AnnotationAssertion(rdfs:label "negative regulation of steroid hormone secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of steroid hormone secretion) - -AnnotationAssertion(Annotation( "GOC:sl") "Any process that activates or increases the frequency, rate or extent of steroid hormone secretion.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-07-26T08:38:51Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000833") -AnnotationAssertion(rdfs:label "positive regulation of steroid hormone secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of androgen secretion) - -AnnotationAssertion(Annotation( "GOC:sl") "Any process that modulates the frequency, rate or extent of androgen secretion.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-07-26T08:39:45Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000834") -AnnotationAssertion(rdfs:label "regulation of androgen secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of androgen secretion) - -AnnotationAssertion(Annotation( "GOC:sl") "Any process that stops, prevents or reduces the frequency, rate or extent of androgen secretion.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-07-26T08:39:48Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000835") -AnnotationAssertion(rdfs:label "negative regulation of androgen secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of androgen secretion) - -AnnotationAssertion(Annotation( "GOC:sl") "Any process that activates or increases the frequency, rate or extent of androgen secretion.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-07-26T08:39:51Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000836") -AnnotationAssertion(rdfs:label "positive regulation of androgen secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of testosterone secretion) - -AnnotationAssertion(Annotation( "GOC:sl") "Any process that modulates the frequency, rate or extent of testosterone secretion.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-07-26T08:42:29Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000843") -AnnotationAssertion(rdfs:label "regulation of testosterone secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of testosterone secretion) - -AnnotationAssertion(Annotation( "GOC:sl") "Any process that stops, prevents or reduces the frequency, rate or extent of testosterone secretion.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-07-26T08:42:33Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000844") -AnnotationAssertion(rdfs:label "negative regulation of testosterone secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of testosterone secretion) - -AnnotationAssertion(Annotation( "GOC:sl") "Any process that activates or increases the frequency, rate or extent of testosterone secretion.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-07-26T08:42:36Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000845") -AnnotationAssertion(rdfs:label "positive regulation of testosterone secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of corticosteroid hormone secretion) - -AnnotationAssertion(Annotation( "GOC:sl") "Any process that modulates the frequency, rate or extent of corticosteroid hormone secretion.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-07-26T08:43:38Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of corticosteroid secretion") -AnnotationAssertion( "GO:2000846") -AnnotationAssertion(rdfs:label "regulation of corticosteroid hormone secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (negative regulation of corticosteroid hormone secretion) - -AnnotationAssertion(Annotation( "GOC:sl") "Any process that stops, prevents or reduces the frequency, rate or extent of corticosteroid hormone secretion.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-07-26T08:43:42Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of corticosteroid secretion") -AnnotationAssertion( "GO:2000847") -AnnotationAssertion(rdfs:label "negative regulation of corticosteroid hormone secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of corticosteroid hormone secretion) - -AnnotationAssertion(Annotation( "GOC:sl") "Any process that activates or increases the frequency, rate or extent of corticosteroid hormone secretion.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-07-26T08:43:45Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of corticosteroid secretion") -AnnotationAssertion( "GO:2000848") -AnnotationAssertion(rdfs:label "positive regulation of corticosteroid hormone secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of glucocorticoid secretion) - -AnnotationAssertion(Annotation( "GOC:sl") "Any process that modulates the frequency, rate or extent of glucocorticoid secretion.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-07-26T08:44:43Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000849") -AnnotationAssertion(rdfs:label "regulation of glucocorticoid secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of glucocorticoid secretion) - -AnnotationAssertion(Annotation( "GOC:sl") "Any process that stops, prevents or reduces the frequency, rate or extent of glucocorticoid secretion.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-07-26T08:44:48Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000850") -AnnotationAssertion(rdfs:label "negative regulation of glucocorticoid secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of glucocorticoid secretion) - -AnnotationAssertion(Annotation( "GOC:sl") "Any process that activates or increases the frequency, rate or extent of glucocorticoid secretion.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-07-26T08:44:51Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000851") -AnnotationAssertion(rdfs:label "positive regulation of glucocorticoid secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of mineralocorticoid secretion) - -AnnotationAssertion(Annotation( "GOC:sl") "Any process that modulates the frequency, rate or extent of mineralocorticoid secretion.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-07-26T08:46:38Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000855") -AnnotationAssertion(rdfs:label "regulation of mineralocorticoid secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (negative regulation of mineralocorticoid secretion) - -AnnotationAssertion(Annotation( "GOC:sl") "Any process that stops, prevents or reduces the frequency, rate or extent of mineralocorticoid secretion.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-07-26T08:46:42Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000856") -AnnotationAssertion(rdfs:label "negative regulation of mineralocorticoid secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of mineralocorticoid secretion) - -AnnotationAssertion(Annotation( "GOC:sl") "Any process that activates or increases the frequency, rate or extent of mineralocorticoid secretion.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-07-26T08:46:45Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000857") -AnnotationAssertion(rdfs:label "positive regulation of mineralocorticoid secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of aldosterone secretion) - -AnnotationAssertion(Annotation( "GOC:sl") "Any process that modulates the frequency, rate or extent of aldosterone secretion.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-07-26T08:47:27Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000858") -AnnotationAssertion(rdfs:label "regulation of aldosterone secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (negative regulation of aldosterone secretion) - -AnnotationAssertion(Annotation( "GOC:sl") "Any process that stops, prevents or reduces the frequency, rate or extent of aldosterone secretion.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-07-26T08:47:31Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000859") -AnnotationAssertion(rdfs:label "negative regulation of aldosterone secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of aldosterone secretion) - -AnnotationAssertion(Annotation( "GOC:sl") "Any process that activates or increases the frequency, rate or extent of aldosterone secretion.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-07-26T08:47:34Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000860") -AnnotationAssertion(rdfs:label "positive regulation of aldosterone secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of progesterone secretion) - -AnnotationAssertion(Annotation( "GOC:sl") "Any process that modulates the frequency, rate or extent of progesterone secretion.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-07-26T08:51:14Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000870") -AnnotationAssertion(rdfs:label "regulation of progesterone secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of progesterone secretion) - -AnnotationAssertion(Annotation( "GOC:sl") "Any process that stops, prevents or reduces the frequency, rate or extent of progesterone secretion.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-07-26T08:51:19Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000871") -AnnotationAssertion(rdfs:label "negative regulation of progesterone secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of progesterone secretion) - -AnnotationAssertion(Annotation( "GOC:sl") "Any process that activates or increases the frequency, rate or extent of progesterone secretion.") -AnnotationAssertion( "bf") -AnnotationAssertion( "2011-07-26T08:51:22Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000872") -AnnotationAssertion(rdfs:label "positive regulation of progesterone secretion") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of pro-B cell differentiation) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of pro-B cell differentiation.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2011-08-02T03:05:45Z") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of pro-B lymphocyte differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of pro-B cell development") -AnnotationAssertion( "GO:2000973") -AnnotationAssertion(rdfs:label "regulation of pro-B cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of pro-B cell differentiation) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of pro-B cell differentiation.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2011-08-02T03:05:50Z") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of pro-B lymphocyte differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of pro-B cell development") -AnnotationAssertion( "GO:2000974") -AnnotationAssertion(rdfs:label "negative regulation of pro-B cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of pro-B cell differentiation) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of pro-B cell differentiation.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2011-08-02T03:05:53Z") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of pro-B lymphocyte differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of pro-B cell development") -AnnotationAssertion( "GO:2000975") -AnnotationAssertion(rdfs:label "positive regulation of pro-B cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of forebrain neuron differentiation) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of forebrain neuron differentiation.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2011-08-03T12:09:12Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000977") -AnnotationAssertion(rdfs:label "regulation of forebrain neuron differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of forebrain neuron differentiation) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of forebrain neuron differentiation.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2011-08-03T12:09:16Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000978") -AnnotationAssertion(rdfs:label "negative regulation of forebrain neuron differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of forebrain neuron differentiation) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of forebrain neuron differentiation.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2011-08-03T12:09:19Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000979") -AnnotationAssertion(rdfs:label "positive regulation of forebrain neuron differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of inner ear receptor cell differentiation) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of inner ear receptor cell differentiation.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2011-08-03T02:38:43Z") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of inner ear hair cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000980") -AnnotationAssertion(rdfs:label "regulation of inner ear receptor cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of inner ear receptor cell differentiation) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of inner ear receptor cell differentiation.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2011-08-03T02:38:47Z") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of inner ear hair cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000981") -AnnotationAssertion(rdfs:label "negative regulation of inner ear receptor cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of inner ear receptor cell differentiation) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of inner ear receptor cell differentiation.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2011-08-03T02:38:51Z") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of inner ear hair cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000982") -AnnotationAssertion(rdfs:label "positive regulation of inner ear receptor cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of cellulose catabolic process) - -AnnotationAssertion(Annotation( "GOC:mengo_curators") "Any process that modulates the frequency, rate or extent of cellulose catabolic process.") -AnnotationAssertion( "tt") -AnnotationAssertion( "2011-08-08T03:21:20Z") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of cellulose breakdown") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of cellulose catabolism") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of cellulose degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000997") -AnnotationAssertion(rdfs:label "regulation of cellulose catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of cellulose catabolic process) - -AnnotationAssertion(Annotation( "GOC:mengo_curators") "Any process that stops, prevents or reduces the frequency, rate or extent of cellulose catabolic process.") -AnnotationAssertion( "tt") -AnnotationAssertion( "2011-08-08T03:21:26Z") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of cellulose breakdown") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of cellulose catabolism") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of cellulose degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000998") -AnnotationAssertion(rdfs:label "negative regulation of cellulose catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of cellulose catabolic process) - -AnnotationAssertion(Annotation( "GOC:mengo_curators") "Any process that activates or increases the frequency, rate or extent of cellulose catabolic process.") -AnnotationAssertion( "tt") -AnnotationAssertion( "2011-08-08T03:21:30Z") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of cellulose breakdown") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of cellulose catabolism") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of cellulose degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2000999") -AnnotationAssertion(rdfs:label "positive regulation of cellulose catabolic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of cellulose biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:mengo_curators") "Any process that modulates the frequency, rate or extent of cellulose biosynthetic process.") -AnnotationAssertion( "tt") -AnnotationAssertion( "2011-08-08T08:42:17Z") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of cellulose anabolism") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of cellulose biosynthesis") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of cellulose formation") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of cellulose synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2001006") -AnnotationAssertion(rdfs:label "regulation of cellulose biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of cellulose biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:mengo_curators") "Any process that stops, prevents or reduces the frequency, rate or extent of cellulose biosynthetic process.") -AnnotationAssertion( "tt") -AnnotationAssertion( "2011-08-08T08:42:24Z") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of cellulose anabolism") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of cellulose biosynthesis") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of cellulose formation") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of cellulose synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2001007") -AnnotationAssertion(rdfs:label "negative regulation of cellulose biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of cellulose biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:mengo_curators") "Any process that activates or increases the frequency, rate or extent of cellulose biosynthetic process.") -AnnotationAssertion( "tt") -AnnotationAssertion( "2011-08-08T08:42:29Z") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of cellulose anabolism") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of cellulose biosynthesis") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of cellulose formation") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of cellulose synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2001008") -AnnotationAssertion(rdfs:label "positive regulation of cellulose biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (mesenchymal cell differentiation involved in renal system development) - -AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") Annotation( "GOC:obol") Annotation( "GOC:yaf") "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of the renal system as it progresses from its formation to the mature state.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2011-08-09T04:05:14Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:obol") "mesenchymal cell differentiation involved in urinary system development") -AnnotationAssertion(Annotation( "GOC:obol") "mesenchymal cell differentiation involved in urinary tract development") -AnnotationAssertion( "GO:2001012") -AnnotationAssertion(rdfs:label "mesenchymal cell differentiation involved in renal system development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (epithelial cell proliferation involved in renal tubule morphogenesis) - -AnnotationAssertion(Annotation( "GOC:obol") "Any epithelial cell proliferation that is involved in renal tubule morphogenesis.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2011-08-12T11:37:29Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2001013") -AnnotationAssertion(rdfs:label "epithelial cell proliferation involved in renal tubule morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of skeletal muscle cell differentiation) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of skeletal muscle cell differentiation.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2011-08-11T08:54:37Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2001014") -AnnotationAssertion(rdfs:label "regulation of skeletal muscle cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of skeletal muscle cell differentiation) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle cell differentiation.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2011-08-11T08:54:41Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2001015") -AnnotationAssertion(rdfs:label "negative regulation of skeletal muscle cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of skeletal muscle cell differentiation) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of skeletal muscle cell differentiation.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2011-08-11T08:54:44Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2001016") -AnnotationAssertion(rdfs:label "positive regulation of skeletal muscle cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of retrograde axon cargo transport) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of retrograde axon cargo transport.") -AnnotationAssertion( "kmv") -AnnotationAssertion( "2011-08-11T09:44:42Z") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of retrograde axonal transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2001017") -AnnotationAssertion(rdfs:label "regulation of retrograde axon cargo transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of retrograde axon cargo transport) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of retrograde axon cargo transport.") -AnnotationAssertion( "kmv") -AnnotationAssertion( "2011-08-11T09:44:46Z") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of retrograde axonal transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2001018") -AnnotationAssertion(rdfs:label "negative regulation of retrograde axon cargo transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of retrograde axon cargo transport) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of retrograde axon cargo transport.") -AnnotationAssertion( "kmv") -AnnotationAssertion( "2011-08-11T09:44:49Z") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of retrograde axonal transport") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2001019") -AnnotationAssertion(rdfs:label "positive regulation of retrograde axon cargo transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of endothelial cell chemotaxis) - -AnnotationAssertion(Annotation( "GOC:BHF") "Any process that modulates the frequency, rate or extent of endothelial cell chemotaxis.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2011-08-22T01:07:26Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2001026") -AnnotationAssertion(rdfs:label "regulation of endothelial cell chemotaxis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of endothelial cell chemotaxis) - -AnnotationAssertion(Annotation( "GOC:BHF") "Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell chemotaxis.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2011-08-22T01:07:31Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2001027") -AnnotationAssertion(rdfs:label "negative regulation of endothelial cell chemotaxis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of endothelial cell chemotaxis) - -AnnotationAssertion(Annotation( "GOC:BHF") "Any process that activates or increases the frequency, rate or extent of endothelial cell chemotaxis.") -AnnotationAssertion( "rl") -AnnotationAssertion( "2011-08-22T01:07:34Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2001028") -AnnotationAssertion(rdfs:label "positive regulation of endothelial cell chemotaxis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of tongue muscle cell differentiation) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of tongue muscle cell differentiation.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2011-08-24T11:10:16Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2001035") -AnnotationAssertion(rdfs:label "regulation of tongue muscle cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of tongue muscle cell differentiation) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of tongue muscle cell differentiation.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2011-08-24T11:10:20Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2001036") -AnnotationAssertion(rdfs:label "negative regulation of tongue muscle cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of tongue muscle cell differentiation) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of tongue muscle cell differentiation.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2011-08-24T11:10:22Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2001037") -AnnotationAssertion(rdfs:label "positive regulation of tongue muscle cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of tendon cell differentiation) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of tendon cell differentiation.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2011-09-01T09:20:32Z") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of muscle attachment cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of tenocyte differentiation") -AnnotationAssertion( "GO:2001049") -AnnotationAssertion(rdfs:label "regulation of tendon cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of tendon cell differentiation) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of tendon cell differentiation.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2011-09-01T09:20:38Z") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of muscle attachment cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of tenocyte differentiation") -AnnotationAssertion( "GO:2001050") -AnnotationAssertion(rdfs:label "negative regulation of tendon cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of tendon cell differentiation) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of tendon cell differentiation.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2011-09-01T09:20:42Z") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of muscle attachment cell differentiation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of tenocyte differentiation") -AnnotationAssertion( "GO:2001051") -AnnotationAssertion(rdfs:label "positive regulation of tendon cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of mesenchymal cell apoptotic process) - -AnnotationAssertion(Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of mesenchymal cell apoptotic process.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2011-09-08T02:49:59Z") -AnnotationAssertion( "regulation of mesenchymal cell apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2001053") -AnnotationAssertion(rdfs:label "regulation of mesenchymal cell apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of mesenchymal cell apoptotic process) - -AnnotationAssertion(Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal cell apoptotic process.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2011-09-08T02:50:05Z") -AnnotationAssertion( "negative regulation of mesenchymal cell apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2001054") -AnnotationAssertion(rdfs:label "negative regulation of mesenchymal cell apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of mesenchymal cell apoptotic process) - -AnnotationAssertion(Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of mesenchymal cell apoptotic process.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2011-09-08T02:50:09Z") -AnnotationAssertion( "positive regulation of mesenchymal cell apoptosis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2001055") -AnnotationAssertion(rdfs:label "positive regulation of mesenchymal cell apoptotic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (glycogen binding) - -AnnotationAssertion(Annotation( "GOC:mengo_curators") "Binding to glycogen.") -AnnotationAssertion( "jl") -AnnotationAssertion( "2011-09-14T12:01:06Z") -AnnotationAssertion( "molecular_function") -AnnotationAssertion(Annotation( "GOC:obol") "animal starch binding") -AnnotationAssertion(Annotation( "GOC:obol") "liver starch binding") -AnnotationAssertion( "GO:2001069") -AnnotationAssertion(rdfs:label "glycogen binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of phospholipid transport) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of phospholipid transport.") -AnnotationAssertion( "kmv") -AnnotationAssertion( "2011-10-14T06:16:06Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2001138") -AnnotationAssertion(rdfs:label "regulation of phospholipid transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of phospholipid transport) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of phospholipid transport.") -AnnotationAssertion( "kmv") -AnnotationAssertion( "2011-10-14T06:16:11Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2001139") -AnnotationAssertion(rdfs:label "negative regulation of phospholipid transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of phospholipid transport) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of phospholipid transport.") -AnnotationAssertion( "kmv") -AnnotationAssertion( "2011-10-14T06:16:14Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2001140") -AnnotationAssertion(rdfs:label "positive regulation of phospholipid transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of RNA biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:dph") "Any process that modulates the frequency, rate or extent of RNA biosynthetic process.") -AnnotationAssertion( "dph") -AnnotationAssertion( "2011-10-17T11:36:25Z") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of RNA anabolism") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of RNA biosynthesis") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of RNA formation") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of RNA synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2001141") -AnnotationAssertion(rdfs:label "regulation of RNA biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of renal water transport) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of renal water transport.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2011-10-24T11:37:51Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2001151") -AnnotationAssertion(rdfs:label "regulation of renal water transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (negative regulation of renal water transport) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of renal water transport.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2011-10-24T11:37:57Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2001152") -AnnotationAssertion(rdfs:label "negative regulation of renal water transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (positive regulation of renal water transport) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of renal water transport.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2011-10-24T11:38:01Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2001153") -AnnotationAssertion(rdfs:label "positive regulation of renal water transport") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ) - -# Class: (regulation of ATP biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of ATP biosynthetic process.") -AnnotationAssertion( "kmv") -AnnotationAssertion( "2011-10-26T03:18:03Z") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of ATP anabolism") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of ATP biosynthesis") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of ATP formation") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of ATP synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of ATP regeneration") -AnnotationAssertion( "GO:2001169") -AnnotationAssertion(rdfs:label "regulation of ATP biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of ATP biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of ATP biosynthetic process.") -AnnotationAssertion( "kmv") -AnnotationAssertion( "2011-10-26T03:18:13Z") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of ATP anabolism") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of ATP biosynthesis") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of ATP formation") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of ATP synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of ATP regeneration") -AnnotationAssertion( "GO:2001170") -AnnotationAssertion(rdfs:label "negative regulation of ATP biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of ATP biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of ATP biosynthetic process.") -AnnotationAssertion( "kmv") -AnnotationAssertion( "2011-10-26T03:18:26Z") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of ATP anabolism") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of ATP biosynthesis") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of ATP formation") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of ATP synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of ATP regeneration") -AnnotationAssertion( "GO:2001171") -AnnotationAssertion(rdfs:label "positive regulation of ATP biosynthetic process") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of dendritic cell differentiation) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of dendritic cell differentiation.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2011-11-04T02:01:27Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2001198") -AnnotationAssertion(rdfs:label "regulation of dendritic cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of dendritic cell differentiation) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell differentiation.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2011-11-04T02:01:33Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2001199") -AnnotationAssertion(rdfs:label "negative regulation of dendritic cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of dendritic cell differentiation) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of dendritic cell differentiation.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2011-11-04T02:01:36Z") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2001200") -AnnotationAssertion(rdfs:label "positive regulation of dendritic cell differentiation") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of osteoclast development) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of osteoclast development.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2011-11-10T10:58:59Z") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of osteoclast cell development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2001204") -AnnotationAssertion(rdfs:label "regulation of osteoclast development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of osteoclast development) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of osteoclast development.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2011-11-10T10:59:06Z") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of osteoclast cell development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2001205") -AnnotationAssertion(rdfs:label "negative regulation of osteoclast development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of osteoclast development) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of osteoclast development.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2011-11-10T10:59:12Z") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of osteoclast cell development") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2001206") -AnnotationAssertion(rdfs:label "positive regulation of osteoclast development") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (regulation of vasculogenesis) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of vasculogenesis.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2011-11-15T01:22:31Z") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of vascular morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2001212") -AnnotationAssertion(rdfs:label "regulation of vasculogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (negative regulation of vasculogenesis) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of vasculogenesis.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2011-11-15T01:22:36Z") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of vascular morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2001213") -AnnotationAssertion(rdfs:label "negative regulation of vasculogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of vasculogenesis) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of vasculogenesis.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2011-11-15T01:22:39Z") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of vascular morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2001214") -AnnotationAssertion(rdfs:label "positive regulation of vasculogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of neuron migration) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of neuron migration.") -AnnotationAssertion( "kmv") -AnnotationAssertion( "2011-11-17T10:01:38Z") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of neuron chemotaxis") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of neuronal migration") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:obol") "regulation of neuron guidance") -AnnotationAssertion( "GO:2001222") -AnnotationAssertion(rdfs:label "regulation of neuron migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - -# Class: (negative regulation of neuron migration) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of neuron migration.") -AnnotationAssertion( "kmv") -AnnotationAssertion( "2011-11-17T10:01:45Z") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of neuron chemotaxis") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of neuronal migration") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of neuron guidance") -AnnotationAssertion( "GO:2001223") -AnnotationAssertion(rdfs:label "negative regulation of neuron migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of neuron migration) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of neuron migration.") -AnnotationAssertion( "kmv") -AnnotationAssertion( "2011-11-17T10:01:49Z") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of neuron chemotaxis") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of neuronal migration") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of neuron guidance") -AnnotationAssertion( "GO:2001224") -AnnotationAssertion(rdfs:label "positive regulation of neuron migration") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (regulation of apoptotic signaling pathway) - -AnnotationAssertion(Annotation( "GOC:mtg_apoptosis") "Any process that modulates the frequency, rate or extent of apoptotic signaling pathway.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2011-11-24T01:20:49Z") -AnnotationAssertion(Annotation( "GOC:mah") "regulation of apoptotic signalling pathway") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2001233") -AnnotationAssertion(rdfs:label "regulation of apoptotic signaling pathway") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (negative regulation of apoptotic signaling pathway) - -AnnotationAssertion(Annotation( "GOC:mtg_apoptosis") "Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic signaling pathway.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2011-11-24T01:20:54Z") -AnnotationAssertion(Annotation( "GOC:mah") "negative regulation of apoptotic signalling pathway") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2001234") -AnnotationAssertion(rdfs:label "negative regulation of apoptotic signaling pathway") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (positive regulation of apoptotic signaling pathway) - -AnnotationAssertion(Annotation( "GOC:mtg_apoptosis") "Any process that activates or increases the frequency, rate or extent of apoptotic signaling pathway.") -AnnotationAssertion( "pr") -AnnotationAssertion( "2011-11-24T01:20:58Z") -AnnotationAssertion(Annotation( "GOC:mah") "positive regulation of apoptotic signalling pathway") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:2001235") -AnnotationAssertion(rdfs:label "positive regulation of apoptotic signaling pathway") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) - -# Class: (negative regulation of chromosome organization) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of chromosome organization.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2011-12-02T02:01:20Z") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of chromosome organisation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of chromosome organization and biogenesis") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of maintenance of genome integrity") -AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of nuclear genome maintenance") -AnnotationAssertion( "GO:2001251") -AnnotationAssertion(rdfs:label "negative regulation of chromosome organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - -# Class: (positive regulation of chromosome organization) - -AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of chromosome organization.") -AnnotationAssertion( "yaf") -AnnotationAssertion( "2011-12-02T02:01:26Z") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of chromosome organisation") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of chromosome organization and biogenesis") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of maintenance of genome integrity") -AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of nuclear genome maintenance") -AnnotationAssertion( "GO:2001252") -AnnotationAssertion(rdfs:label "positive regulation of chromosome organization") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (body part movement) AnnotationAssertion( "A change of place or position of part of an organism that does not involve the entire organism [NBO:SMAC]") @@ -137700,30 +28211,6 @@ AnnotationAssertion( "grooming behavior") SubClassOf( ) -# Class: (regulation of eating behavior) - -AnnotationAssertion(Annotation( "NBO:GVG") "A feeding behavior associated with the intake or the frequency of intake or preference or manner of intake of food.") -AnnotationAssertion( "2011-04-14T01:20:02Z") -AnnotationAssertion( "George Gkoutos") -AnnotationAssertion( "eating behaviour") -AnnotationAssertion( "behavior_ontology") -AnnotationAssertion( "GO:0042755") -AnnotationAssertion(rdfs:label "regulation of eating behavior") -EquivalentClasses( ObjectSomeValuesFrom( )) -SubClassOf( ) - -# Class: (regulation of drinking behavior) - -AnnotationAssertion(Annotation( "NBO:GVG") "A feeding behavior associated with the intake or the frequency of intake or preference or manner of intake of liquids.") -AnnotationAssertion( "2011-04-14T01:20:02Z") -AnnotationAssertion( "George Gkoutos") -AnnotationAssertion( "drinking behaviour") -AnnotationAssertion( "behavior_ontology") -AnnotationAssertion( "GO:0042756") -AnnotationAssertion(rdfs:label "regulation of drinking behavior") -EquivalentClasses( ObjectSomeValuesFrom( )) -SubClassOf( ) - # Class: (chewing) AnnotationAssertion( "The act of repeated grinding, tearing, and or crushing with teeth or jaws [NBO:SMAC]") @@ -137745,42 +28232,8 @@ AnnotationAssertion( "behavior_ontology") AnnotationAssertion( "GO:0007631") AnnotationAssertion(rdfs:label "feeding behavior") -EquivalentClasses( ObjectIntersectionOf( ObjectUnionOf(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )))) SubClassOf( ) -# Class: (liquid consumption) - -AnnotationAssertion(Annotation( "NBO:GVG") "A behavior associated with the intake of liquid.") -AnnotationAssertion( "2011-03-31T12:40:37Z") -AnnotationAssertion( "George Gkoutos") -AnnotationAssertion( "behavior_ontology") -AnnotationAssertion(rdfs:label "liquid consumption") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (water consumption) - -AnnotationAssertion(Annotation( "NBO:GVG") "A drinking behavior associated with the intake of water.") -AnnotationAssertion( "2011-03-31T12:41:14Z") -AnnotationAssertion( "George Gkoutos") -AnnotationAssertion( "behavior_ontology") -AnnotationAssertion( "GO:0045187") -AnnotationAssertion(rdfs:label "water consumption") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (food consumption) - -AnnotationAssertion(Annotation( "NBO:GVG") "A feeding behavior associated with the intake of food.") -AnnotationAssertion( "2011-03-31T12:42:46Z") -AnnotationAssertion( "George Gkoutos") -AnnotationAssertion( "behavior_ontology") -AnnotationAssertion(rdfs:label "food consumption") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (sensation behavior) AnnotationAssertion(Annotation( "NBO:GVG") "Cognitive perception of a sensation by any of the five senses -- vision, touch, smell, taste, and hearing.") @@ -137875,28 +28328,6 @@ AnnotationAssertion( "posture") SubClassOf( ) -# Class: (body posture) - -AnnotationAssertion(Annotation( "NBO:GVG") "Intentionally or habitually assumed arrangement of the body.") -AnnotationAssertion( "2011-04-06T09:30:45Z") -AnnotationAssertion( "George Gkoutos") -AnnotationAssertion( "behavior_ontology") -AnnotationAssertion(rdfs:label "body posture") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (limb posture) - -AnnotationAssertion(Annotation( "NBO:GVG") "Intentionally or habitually assumed arrangement of the limbs.") -AnnotationAssertion( "2011-04-06T09:31:06Z") -AnnotationAssertion( "George Gkoutos") -AnnotationAssertion( "behavior_ontology") -AnnotationAssertion(rdfs:label "limb posture") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (gait) AnnotationAssertion( "\"The pattern of movement of the limbs of animals, characterized by elements of progression, stability, speed and length over the ground.\" [MP:0001406]") @@ -137925,7 +28356,6 @@ AnnotationAssertion( "reflex behaviour") AnnotationAssertion( "behavior_ontology") AnnotationAssertion(rdfs:label "reflexive behavior") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) @@ -138006,15 +28436,6 @@ AnnotationAssertion( "perception behavior by means") SubClassOf( ) -# Class: (regulation of behavior) - -AnnotationAssertion( "\"Any process that modulates the frequency, rate or extent of behavior, the specific actions or reactions of an organism in response to external or internal stimuli.\" [GO:0050795]") -AnnotationAssertion( "George Gkoutos") -AnnotationAssertion( "GO:0050795") -AnnotationAssertion(rdfs:label "regulation of behavior"@en) -EquivalentClasses( ObjectSomeValuesFrom( )) -SubClassOf( ) - # Class: (consumption behavior) AnnotationAssertion(Annotation( "NBOC:GVG") "Behavior related to the intake of substances.") @@ -138023,30 +28444,6 @@ AnnotationAssertion( "consumption behavior"@en) SubClassOf( ) -# Class: (regulation of consumption behavior) - -AnnotationAssertion(Annotation( "NBOC:GVG") "Any process that modulates the frequency, rate or extent of consumption behavior, the specific actions or reactions of an organism in response to external or internal stimuli.") -AnnotationAssertion( "George Gkoutos") -AnnotationAssertion(rdfs:label "regulation of consumption behavior"@en) -EquivalentClasses( ObjectSomeValuesFrom( )) -SubClassOf( ) - -# Class: (regulation of feeding behavior) - -AnnotationAssertion(Annotation( "NBOC:GVG") "Any process that modulates the frequency, rate or extent of consumption of food or liquid") -AnnotationAssertion( "George Gkoutos") -AnnotationAssertion(rdfs:label "regulation of feeding behavior"@en) -EquivalentClasses( ObjectSomeValuesFrom( ObjectUnionOf( ))) -SubClassOf( ) - -# Class: (regulation of water consumption) - -AnnotationAssertion(Annotation( "NBOC:GVG") "Any process that modulates the frequency, rate or extent of water consumption, the specific actions or reactions of an organism in response to external or internal stimuli.") -AnnotationAssertion( "George Gkoutos") -AnnotationAssertion(rdfs:label "regulation of water consumption"@en) -EquivalentClasses( ObjectSomeValuesFrom( )) -SubClassOf( ) - # Class: (root) AnnotationAssertion( "GC_ID:1") @@ -143526,33 +33923,6 @@ AnnotationAssertion( "spatial pattern") SubClassOf( ) -# Class: (qualitative) - -AnnotationAssertion( "quality") -AnnotationAssertion( "PATO:0000068") -AnnotationAssertion(rdfs:comment "TODO: define this or obsolete it and move children somewhere else.") -AnnotationAssertion(rdfs:label "qualitative") -SubClassOf( ) - -# Class: (deviation (from_normal)) - -AnnotationAssertion(Annotation( "PATOC:GVG") "A quality inhering in a bearer by virtue of the whether the bearer differs from normal or average.") -AnnotationAssertion( "quality") -AnnotationAssertion( "PATO:0000069") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "deviation (from_normal)") -SubClassOf( ) - -# Class: (size) - -AnnotationAssertion(Annotation( "WordNet:WordNet") "A morphology quality inhering in a bearer by virtue of the bearer's physical magnitude.") -AnnotationAssertion( "quality") -AnnotationAssertion( "PATO:0000117") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "size") -SubClassOf( ) - # Class: (closure) AnnotationAssertion(Annotation( "PATOC:CJM") Annotation( "PATOC:GVG") "A morphological quality pertaining to the degree to which an object contains an opening, aperture, orifice or vent.") @@ -143693,37 +34063,6 @@ AnnotationAssertion( "uncoiled") SubClassOf( ) -# Class: (normal) - -AnnotationAssertion(Annotation( "PATOC:GVG") "A quality inhering in a bearer by virtue of the bearer's exhibiting no deviation from normal or average.") -AnnotationAssertion( ) -AnnotationAssertion( "quality") -AnnotationAssertion( "average") -AnnotationAssertion( "PATO:0000461") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "normal") -SubClassOf( ) - -# Class: (increased size) - -AnnotationAssertion(Annotation( "PATOC:GVG") "A size quality which is relatively high.") -AnnotationAssertion( ) -AnnotationAssertion( "PATO:0001202") -AnnotationAssertion( "quality") -AnnotationAssertion( "big") -AnnotationAssertion( "enlarged") -AnnotationAssertion( "expanded") -AnnotationAssertion( "great") -AnnotationAssertion( "large") -AnnotationAssertion( "PATO:0000586") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "increased size") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - # Class: (vestigial) AnnotationAssertion(Annotation( "PATOC:MAH") "A quality inhering in a bearer by virtue of the bearer's being a remnant structure from earlier development or evolution.") @@ -144039,16 +34378,6 @@ AnnotationAssertion( "ploidy") SubClassOf( ) -# Class: (haploid) - -AnnotationAssertion(Annotation( "Wikipedia:http://en.wikipedia.org/wiki/Haploid") "A ploidy quality inhering in a bearer by virtue of the bearer's containing a single set of homologous chromosomes.") -AnnotationAssertion( "quality") -AnnotationAssertion( "PATO:0001375") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "haploid") -SubClassOf( ) - # Class: (euploid) AnnotationAssertion(Annotation( "Wikipedia:http://en.wikipedia.org/wiki/Euploid") "A ploidy quality inhering in a bearer by virtue of the bearer's containing an integral multiple of the monoploid number, possibly excluding the sex-determining chromosomes.") @@ -144059,17 +34388,6 @@ AnnotationAssertion( "euploid") SubClassOf( ) -# Class: (diploid) - -AnnotationAssertion(Annotation( "Wikipedia:http://en.wikipedia.org/wiki/Diploid") "A ploidy quality inhering in a bearer by virtue of the bearer's having two copies (homologs) of each chromosome, usually one from the mother and one from the father.") -AnnotationAssertion( "quality") -AnnotationAssertion( "PATO:0001394") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "The exact number may be one or two different from the 2n number and still be classified as diploidy (although with aneuploidy). Nearly all mammals are diploid organisms, although all individuals have some small fraction of cells that are polyploidy.") -AnnotationAssertion(rdfs:label "diploid") -SubClassOf( ) - # Class: (cellular quality) AnnotationAssertion(Annotation( "PATOC:GVG") "A monadic quality of continuant that exists at the cellular level of organisation.") @@ -144078,51 +34396,6 @@ AnnotationAssertion( "cellular quality") SubClassOf( ) -# Class: (cellular potency) - -AnnotationAssertion(Annotation( "PATOC:GVG") "A cellular quality that arises by virtue of whether the bearer's disposition to differentiate into one or more mature cell types.") -AnnotationAssertion( "quality") -AnnotationAssertion( "PATO:0001397") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "cellular potency") -SubClassOf( ) - -# Class: (unipotent) - -AnnotationAssertion(Annotation( "Wikipedia:http://en.wikipedia.org/wiki/Unipotent") "A cellular potency that is the capacity to produce only one differentiated cell type.") -AnnotationAssertion( "quality") -AnnotationAssertion( "PATO:0001400") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "Unipotent cells have the quality of self-renewal which distinguishes them from non-stem cells.") -AnnotationAssertion(rdfs:label "unipotent") -SubClassOf( ) - -# Class: (oligopotent) - -AnnotationAssertion(Annotation( "PATOC:MAH") "A cellular potency that is the capacity to form multiple differentiated cell types of a specific lineage and lack self renewing capacity.") -AnnotationAssertion( "quality") -AnnotationAssertion( "PATO:0001401") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "Less potent than multipotent, often thought of as precursor or progenitor cell status.") -AnnotationAssertion(rdfs:label "oligopotent") -SubClassOf( ) - -# Class: (multipotent) - -AnnotationAssertion(Annotation( "Wikipedia:http://en.wikipedia.org/wiki/Multipotent") "A cellular potency that is the capacity to form multiple differentiated cell types.") -AnnotationAssertion( "quality") -AnnotationAssertion( "PATO:0001402") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "multipotent") -SubClassOf( ) - # Class: (nucleate quality) AnnotationAssertion(Annotation( "PATOC:GVG") "A cellular quality inhering in a bearer by virtue of bearer's number of nuclei.") @@ -144143,49 +34416,6 @@ AnnotationAssertion( "anucleate") SubClassOf( ) -# Class: (binucleate) - -AnnotationAssertion(Annotation( "Biology-online:Biology-online") "A nucleate quality inhering in a bearer by virtue of the bearer's having two nuclei.") -AnnotationAssertion( "quality") -AnnotationAssertion( "PATO:0001406") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "binucleate") -SubClassOf( ) - -# Class: (mononucleate) - -AnnotationAssertion(Annotation( "Biology-online:Biology-online") "A nucleate quality inhering in a bearer by virtue of the bearer's having one nucleus.") -AnnotationAssertion( "quality") -AnnotationAssertion( "PATO:0001407") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "mononucleate") -SubClassOf( ) - -# Class: (ciliatedness) - -AnnotationAssertion(Annotation( "Wikipedia:http://en.wikipedia.org/wiki/Ciliated") "A cellular quality inhering in a bearer by virtue of the bearer's having thin, tail-like projections extending outwards from the cell body.") -AnnotationAssertion( "quality") -AnnotationAssertion( "PATO:0001408") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "ciliatedness") -SubClassOf( ) - -# Class: (striated) - -AnnotationAssertion(Annotation( "Biology-online:Biology-online") "A shape quality inhering in a bearer by virtue of the bearer's being marked by narrow lines or grooves, usually parallel.") -AnnotationAssertion( "quality") -AnnotationAssertion( "PATO:0001410") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "striated") -SubClassOf( ) - # Class: (sharp) AnnotationAssertion(Annotation( "PATOC:GVG") "A shape quality inhering in a bearer by virtue of the bearer's terminating in a point or edge.") @@ -144196,17 +34426,6 @@ AnnotationAssertion( "sharp") SubClassOf( ) -# Class: (buoyancy) - -AnnotationAssertion(Annotation( "PATOC:GVG") "A physical quality inhering in a bearer by virtue of the bearer's disposition to rise or float in a fluid medium such as water or air.") -AnnotationAssertion( "quality") -AnnotationAssertion( "PATO:0001420") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "buoyancy") -SubClassOf( ) - # Class: (dead) AnnotationAssertion(Annotation( "PATOC:GVG") "A viability quality inhering in a bearer by virtue of the cessation of the bearer's life.") @@ -144246,17 +34465,6 @@ AnnotationAssertion( "tapered") SubClassOf( ) -# Class: (immature) - -AnnotationAssertion(Annotation( "Merriam-Webster:Merriam-Webster") "A quality inhering in a bearer by virtue of the bearer's lacking complete growth, differentiation, or development.") -AnnotationAssertion( ) -AnnotationAssertion( "quality") -AnnotationAssertion( "underdeveloped") -AnnotationAssertion( "PATO:0001501") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "immature") -SubClassOf( ) - # Class: (flexibility) AnnotationAssertion(Annotation( "merriam-webster:merriam-webster") "A physical quality inhering in a bearer by virtue of the bearer's disposition to being turned, bowed, or twisted without breaking.") @@ -144320,20 +34528,6 @@ AnnotationAssertion( "contractility") SubClassOf( ) -# Class: (increased contractility) - -AnnotationAssertion(Annotation( "PATO:GVG") "A contractility which is relatively high.") -AnnotationAssertion( ) -AnnotationAssertion( "high contractility") -AnnotationAssertion( "quality") -AnnotationAssertion( "PATO:0001580") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "increased contractility") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - # Class: (curvature) AnnotationAssertion(Annotation( "WordNet:WordNet") "A surface shape quality inhering in a bearer by virtue of the bearer's exhibiting a degree of bending.") @@ -144343,18 +34537,6 @@ AnnotationAssertion( "curvature") SubClassOf( ) -# Class: (increased curvature) - -AnnotationAssertion(Annotation( "PATO:GVG") "A curvature which is relatively high.") -AnnotationAssertion( ) -AnnotationAssertion( "quality") -AnnotationAssertion( "PATO:0001592") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "increased curvature") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - # Class: (arched) AnnotationAssertion(Annotation( "WordNet:WordNet") "A concave quality inhering in a bearer by virtue of the bearer's forming or resembling an arch.") @@ -144388,20 +34570,6 @@ AnnotationAssertion(rdfs:comment " AnnotationAssertion(rdfs:label "contractile") SubClassOf( ) -# Class: (increased viscosity) - -AnnotationAssertion(Annotation( "PATOC:GVG") "A viscosity which relatively high.") -AnnotationAssertion( ) -AnnotationAssertion( "high viscosity") -AnnotationAssertion( "quality") -AnnotationAssertion( "PATO:0001693") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "increased viscosity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - # Class: (liquid configuration) AnnotationAssertion(Annotation( "PATOC:GVG") "A physical quality inhering in a bearer by virtue of the bearer's parts having the arrangement which exhibits characteristics of liquids.") @@ -144432,20 +34600,6 @@ AnnotationAssertion( "invaginated") SubClassOf( ) -# Class: (increased flexibility) - -AnnotationAssertion(Annotation( "PATOC:GVG") "A flexibility which is relatively high.") -AnnotationAssertion( ) -AnnotationAssertion( "high flexibility") -AnnotationAssertion( "quality") -AnnotationAssertion( "PATO:0001776") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "increased flexibility") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - # Class: (coiling) AnnotationAssertion(Annotation( "Online_Dictionary:Online_Dictionary") "A shape quality inhering in a bearer by virtue of the bearer's being wound in a continuous series of loops.") @@ -144455,20 +34609,6 @@ AnnotationAssertion( "coiling") SubClassOf( ) -# Class: (increased coiling) - -AnnotationAssertion(Annotation( "PATOC:GVG") "A coiling which is relatively high.") -AnnotationAssertion( ) -AnnotationAssertion( "high coiling") -AnnotationAssertion( "quality") -AnnotationAssertion( "PATO:0001795") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "increased coiling") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - # Class: (acidity) AnnotationAssertion(Annotation( "biology-online:biology-online") "A concentration quality inhering in a bearer by virtue of the bearer's containing acid (hydrogen ions).") @@ -144480,19 +34620,6 @@ AnnotationAssertion( "acidity") SubClassOf( ) -# Class: (increased acidity) - -AnnotationAssertion(Annotation( "PATOC:GVG") "An acidity which is relatively high.") -AnnotationAssertion( ) -AnnotationAssertion( "high acidity") -AnnotationAssertion( "quality") -AnnotationAssertion( "PATO:0001844") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "increased acidity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - # Class: (vertical) AnnotationAssertion(Annotation( "thefreedictionary.com:thefreedictionary.com") "A spatial pattern inhering in a bearer by virtue of the bearer's being situated at right angles to the horizon.") @@ -144552,16 +34679,6 @@ AnnotationAssertion(rdfs:label "tr SubClassOf( ) SubClassOf( ) -# Class: (multinucleate) - -AnnotationAssertion(Annotation( "PATOC:GVG") "A nucleate quality inhering in a bearer by virtue of the bearer's having more than one nucleus.") -AnnotationAssertion( "quality") -AnnotationAssertion( "PATO:0001908") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "multinucleate") -SubClassOf( ) - # Class: (folded) AnnotationAssertion(Annotation( "PATOC:cjm") "A surface feature shape quality inhering in a bearer by virtue of the bearer's one part being layered over another connected part.") @@ -144702,16 +34819,6 @@ AnnotationAssertion( "structure, cavities") SubClassOf( ) -# Class: (biconcave) - -AnnotationAssertion(Annotation( "PATOC:GVG") "A concave quality inhering in a bearer by virtue of the bearer's curving inward on both sides or surfaces.") -AnnotationAssertion( ) -AnnotationAssertion( "quality") -AnnotationAssertion( "PATO:0002039") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "biconcave") -SubClassOf( ) - # Class: (dendritic) AnnotationAssertion(Annotation( "PATOC:cvs") "A branched quality inhering in a bearer by virtue of the bearer's having smaller branches arising from larger branches. Resembling a tree in branching structure.") @@ -144726,20 +34833,6 @@ AnnotationAssertion( "dendritic") SubClassOf( ) -# Class: (increased occurrence) - -AnnotationAssertion(Annotation( "PATOC:GVG") "An occurrence which is relatively high.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "2009-03-26T11:10:11Z") -AnnotationAssertion( "increased incidence") -AnnotationAssertion( "quality") -AnnotationAssertion( "PATO:0002051") -AnnotationAssertion(rdfs:label "increased occurrence") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - # Class: (physical quality of a process) AnnotationAssertion( ) @@ -144761,19 +34854,6 @@ AnnotationAssertion( "hollow") SubClassOf( ) -# Class: (basophilic) - -AnnotationAssertion(Annotation( "PATOC:GVG") "An affinity inhering in an anatomical structure by virtue of the bearer exhibiting a molecular interaction for basic dyes under specific pH conditions.") -AnnotationAssertion( ) -AnnotationAssertion( "2009-10-05T12:05:23Z") -AnnotationAssertion( "quality") -AnnotationAssertion( "PATO:0002094") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "basophilic") -SubClassOf( ) - # Class: (laminar) AnnotationAssertion(Annotation( "PATOC:GVG") "A quality inhering in a bearer by virtue of the bearer's processing the form of a thin plate sheet or layer.") @@ -144786,19 +34866,6 @@ AnnotationAssertion( "laminar") SubClassOf( ) -# Class: (high-arched) - -AnnotationAssertion(Annotation( "PATOC:GVG") "A concave quality inhering in a bearer by virtue of the bearer's forming or resembling an arch of an increased apical height.") -AnnotationAssertion( ) -AnnotationAssertion( "2009-11-26T02:34:06Z") -AnnotationAssertion( "quality") -AnnotationAssertion( "PATO:0002162") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "high-arched") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - # Class: (molecular quality) AnnotationAssertion(Annotation( "PATOC:GVG") "A quality which inheres in a molecular entity, a single molecule, atom, ion, radical etc.") @@ -144881,20 +34948,6 @@ AnnotationAssertion( "3-D shape") SubClassOf( ) -# Class: (increased elasticity) - -AnnotationAssertion(Annotation( "PATOC:GVG") "An elasticity which is relatively high.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "2011-03-30T11:50:21Z") -AnnotationAssertion( "quality") -AnnotationAssertion( "PATO:0002287") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "increased elasticity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - # Class: (tubular) AnnotationAssertion(Annotation( "PATOC:GVG") "A cylindrical shape that is hollow.") @@ -144909,44 +34962,6 @@ AnnotationAssertion(rdfs:label "tu SubClassOf( ) SubClassOf( ) -# Class: (increased quality) - -AnnotationAssertion(Annotation( "PATOC:GVG") "A quality that has a value that is increased compared to normal or average.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "2011-06-16T06:39:43Z") -AnnotationAssertion( "quality") -AnnotationAssertion( "PATO:0002300") -AnnotationAssertion(rdfs:label "increased quality") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) - -# Class: (increased process quality) - -AnnotationAssertion(Annotation( "PATOC:GVG") "A quality of a process that has a value that is increased compared to normal or average.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "2011-06-16T06:53:08Z") -AnnotationAssertion( "quality") -AnnotationAssertion( "PATO:0002304") -AnnotationAssertion(rdfs:label "increased process quality") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - -# Class: (increased object quality) - -AnnotationAssertion(Annotation( "PATOC:GVG") "A quality of an object that has a value that is increased compared to normal or average.") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( "2011-06-16T06:54:01Z") -AnnotationAssertion( "quality") -AnnotationAssertion( "PATO:0002305") -AnnotationAssertion(rdfs:label "increased object quality") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) - # Class: (fiber shaped) AnnotationAssertion(Annotation( "PATOC:DC") "A convex 3-D shape quality inhering in a bearer by virtue of the bearer's exhibiting a by virtue of the bearer's exhibiting a consistently sized and approximately round cross-section along its length, which is many times larger than its diameter.") @@ -144993,20 +35008,6 @@ AnnotationAssertion( "ridged") SubClassOf( ) -# Class: (acidophilic) - -AnnotationAssertion(Annotation( "PATOC:GVG") "An affinity inhering in an anatomical structure by virtue of the bearer exhibiting a molecular interaction for acidic dyes under specific pH conditions.") -AnnotationAssertion( ) -AnnotationAssertion( "2012-12-17T03:01:19Z") -AnnotationAssertion( "eosinophilic") -AnnotationAssertion( "quality") -AnnotationAssertion( "PATO:0002418") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "Eosin stains acidophilic structures, hence eosinophilic is the same as acidophilic.") -AnnotationAssertion(rdfs:label "acidophilic") -SubClassOf( ) - # Class: (acinar) AnnotationAssertion(Annotation( "wikipedia:https://en.wikipedia.org/wiki/Acinus") "Pertaining to the individual parts making up an aggregate fruit like a many-lobed \"berry,\" such as a raspberry.") @@ -145053,44 +35054,6 @@ AnnotationAssertion( "distensible") SubClassOf( ) -# Class: (transversely striated) - -AnnotationAssertion(Annotation( "PATOC:DS") "A shape quality inhering in a bearer by virtue of the bearer's being marked by narrow lines or grooves, usually parallel, that are oriented transversely relative to the long axis of the bearer.") -AnnotationAssertion( ) -AnnotationAssertion( "2013-09-15T12:29:15Z") -AnnotationAssertion( "quality") -AnnotationAssertion( "PATO:0002478") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "transversely striated") -SubClassOf( ) - -# Class: (obliquely striated) - -AnnotationAssertion(Annotation( "PATOC:DS") "A shape quality inhering in a bearer by virtue of the bearer's being marked by narrow lines or grooves, usually parallel, that are oriented obliquely relative to the long axis of the bearer.") -AnnotationAssertion( ) -AnnotationAssertion( "2013-09-15T12:29:42Z") -AnnotationAssertion( "quality") -AnnotationAssertion( "PATO:0002479") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "obliquely striated") -SubClassOf( ) - -# Class: (nucleated) - -AnnotationAssertion(Annotation( "PATOC:GVG") "A nucleate quality inhering in a bearer by virtue of the bearer's having one or more nucleus.") -AnnotationAssertion( ) -AnnotationAssertion( "2013-10-21T05:44:34Z") -AnnotationAssertion( "quality") -AnnotationAssertion( "PATO:0002505") -AnnotationAssertion( ) -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "nucleated") -SubClassOf( ) - # Class: (keratinous) AnnotationAssertion(Annotation( "PATOC:EJS") "A composition quality inhering in a bearer by virtue of the bearer's consisting of keratin.") @@ -145145,17 +35108,6 @@ AnnotationAssertion( "disconnected") SubClassOf( ) -# Class: (cell morphology) - -AnnotationAssertion(Annotation( "ORCID:0000-0002-7073-9172") "A quality of a single cell inhering in the bearer by virtue of the bearer's size or shape or structure.") -AnnotationAssertion( ) -AnnotationAssertion( "2021-01-23T11:31:53Z") -AnnotationAssertion( "quality") -AnnotationAssertion( "PATO:0010006") -AnnotationAssertion(rdfs:comment "Use this term for morphologies that can *only* inhere in a cell, e.g. morphological qualities inhering in a cell by virtue of the presence, location or shape of one or more cell parts.") -AnnotationAssertion(rdfs:label "cell morphology") -SubClassOf( ) - # Class: (polymeric) AnnotationAssertion(Annotation( "GOC:DOS") Annotation( "https://github.com/pato-ontology/pato/issues/78") "A quality inhering in a structure by virtue of it consisting of many of repeated, similar or identical subunits, arranged in some orderly array.") @@ -145175,74 +35127,6 @@ AnnotationAssertion( "distensibility") SubClassOf( ) -# Class: (basket cell morphology) - -AnnotationAssertion(Annotation( "WikipediaVersioned:Basket_cell&oldid=951703880") Annotation( "doi:10.1016/b978-0-12-369497-3.10004-4") "A cell morphology that inheres in multipolar neurons with densely branched terminal axonal arborizations that form basket-like structures surrounding and synapsing to the somas of target cells.") -AnnotationAssertion( ) -AnnotationAssertion( "ILX:0101123") -AnnotationAssertion( "ilxtr:BasketPhenotype") -AnnotationAssertion( "nifext:3") -AnnotationAssertion( "quality") -AnnotationAssertion( "PATO:0070002") -AnnotationAssertion(rdfs:label "basket cell morphology") -SubClassOf( ) - -# Class: (cortical bipolar morphology) - -AnnotationAssertion(Annotation( "PMID:18568015") Annotation( "doi:10.1016/b978-0-12-369497-3.10004-4") "A cell morphology that inheres in neurons which have two principal dendrites that emerge from the soma and begin to branch some distance from it, have few spines, and branch in narrow fields. This is in contrast to bitufted morphology where branching occurs close to the soma.") -AnnotationAssertion( ) -AnnotationAssertion( "ILX:0101312") -AnnotationAssertion( "ilxtr:BipolarPhenotype") -AnnotationAssertion( "nifext:2") -AnnotationAssertion( "quality") -AnnotationAssertion( "PATO:0070006") -AnnotationAssertion(rdfs:comment "This is specific to cortical bipolar cells and are distinguished from retinal bipolar cell morphology which has an axon and dendrite emerging from opposite ends of the soma.") -AnnotationAssertion(rdfs:label "cortical bipolar morphology") -SubClassOf( ) - -# Class: (stellate morphology) - -AnnotationAssertion(Annotation( "ISBN:9780123973481") "A cell morphology that inheres in neurons that have dendritic processes radiating from the cell body forming a star-like shape.") -AnnotationAssertion( ) -AnnotationAssertion( "ILX:0111036") -AnnotationAssertion( "SAO:9271919883") -AnnotationAssertion( "quality") -AnnotationAssertion( "PATO:0070010") -AnnotationAssertion(rdfs:label "stellate morphology") -SubClassOf( ) - -# Class: (pyramidal family morphology) - -AnnotationAssertion(Annotation( "doi:10.1016/b978-0-12-369497-3.10004-4") "A cell morphology that inheres in neurons which have a pyramidal shaped soma, a single axon, a large apical dendrite and multiple basal dendrites.") -AnnotationAssertion( ) -AnnotationAssertion( "ILX:0109553") -AnnotationAssertion( "SAO:1465673360") -AnnotationAssertion( "quality") -AnnotationAssertion( "PATO:0070015") -AnnotationAssertion(rdfs:label "pyramidal family morphology") -SubClassOf( ) - -# Class: (multipolar neuron morphology) - -AnnotationAssertion(Annotation( "WikipediaVersioned:Multipolar_neuron&oldid=1022942606") "A cell morphology that inheres in neurons which possess three or more neurites, usually a single axon and many dendrites and dendritic branches.") -AnnotationAssertion( ) -AnnotationAssertion( "ILX:0107196") -AnnotationAssertion( "NLX:378") -AnnotationAssertion( "quality") -AnnotationAssertion( "PATO:0070026") -AnnotationAssertion(rdfs:label "multipolar neuron morphology") -SubClassOf( ) - -# Class: (bitufted dendrite cell morphology) - -AnnotationAssertion(Annotation( "PMID:18568015") "A cell morphology that inheres in neurons with dendrites that are bidirectional, emerging from opposite ends of the soma, with the two arbors extending in radial or tangential directions.") -AnnotationAssertion( ) -AnnotationAssertion( "quality") -AnnotationAssertion( "PATO:0070027") -AnnotationAssertion(rdfs:comment "This morphology type is distinct from bitufted cell morphology in that it refers to bitufted dendrite morphology rather than bitufted cell morphology.") -AnnotationAssertion(rdfs:label "bitufted dendrite cell morphology") -SubClassOf( ) - # Class: (anatomical structure quality) AnnotationAssertion( "A quality of continuant that exist at the anatomical level of organisation and anything under it. This includes, but is not limited to, cells , tissues, and components.") @@ -145252,33 +35136,6 @@ AnnotationAssertion( "anatomical structure quality") SubClassOf( ) -# Class: (anatomical histological quality) - -AnnotationAssertion( "A quality inhering in an anotomical structure by virtue of its capacity to be stained by specific histological dyes.") -AnnotationAssertion( "http://orcid.org/0000-0001-7258-9596") -AnnotationAssertion( "quality") -AnnotationAssertion( "PATO:0070045") -AnnotationAssertion(rdfs:label "anatomical histological quality") -SubClassOf( ) - -# Class: (neutrophillic) - -AnnotationAssertion(Annotation( "GOC:add") "An affinity inhering in an anatomical structure by virtue of the bearer exhibiting a molecular interaction that stains and colors, pale-pink, with Wright-Giemsa stain.") -AnnotationAssertion( "http://orcid.org/0000-0001-7258-9596") -AnnotationAssertion( "quality") -AnnotationAssertion( "PATO:0070046") -AnnotationAssertion(rdfs:label "neutrophillic") -SubClassOf( ) - -# Class: (polychromatophilic) - -AnnotationAssertion(Annotation( "GOC:add") "An affinity inhering in an anatomical structure by virtue of the bearer exhibiting a molecular interaction for both basic and acid stains under specific pH conditions.") -AnnotationAssertion( "http://orcid.org/0000-0001-7258-9596") -AnnotationAssertion( "quality") -AnnotationAssertion( "PATO:0070047") -AnnotationAssertion(rdfs:label "polychromatophilic") -SubClassOf( ) - # Class: (quality of interaction of a substance with electromagnetic radiation) AnnotationAssertion(Annotation( "https://orcid.org/0000-0002-5111-7263") "A quality of a substance on which or through which electromagnetic radiation impinges or traverses with respect to radiation. This substance quality changes the quality of the incident radiation with respect to any of: intensity, direction, scatter and wavelength.") @@ -145297,1472 +35154,12 @@ AnnotationAssertion( "PR:000000001") AnnotationAssertion(rdfs:comment "The definition above excludes protein complexes, which some also consider a protein. Those who wish to refer to a class representing both senses of the word are directed to CHEBI:36080. Note that the definition allows for experimentally-manipulated genes, and allows for artifically-produced derivatives that mimic those found naturally. Proteins (in the sense defined here) that descended from a common ancestor can be classified into families and superfamilies composed of products of evolutionarily-related genes. The domain architecture of a protein is described by the order of its constituent domains. Proteins with the same domains in the same order are defined as homeomorphic [PRO:WCB].") AnnotationAssertion(rdfs:label "protein") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (CD19 molecule) - -AnnotationAssertion(Annotation( "PMID:15778510") "A protein that is a translation product of the human CD19 gene or a 1:1 ortholog thereof. It is composed of an N-terminal extracellular domain containing two Ig-like C2-type (immunoglobulin-like) domains, followed by a single-pass transmembrane segment and a cytoplasmic C-terminal tail. CD19 expression is restricted to members of the B cell lineage. It functions as a co-receptor for B-cell antigen receptor (BCR), regulating signal transduction.") -AnnotationAssertion( "IUPHARobj:2764") -AnnotationAssertion( "PIRSF:PIRSF016630") -AnnotationAssertion( "B-lymphocyte surface antigen B4") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "CD19") -AnnotationAssertion( "T-cell surface antigen Leu-12") -AnnotationAssertion( "differentiation antigen CD19") -AnnotationAssertion( "protein") -AnnotationAssertion( "PR:000001002") -AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") -AnnotationAssertion(rdfs:label "CD19 molecule") -SubClassOf( ) - -# Class: (CD34 molecule) - -AnnotationAssertion(Annotation( "PMID:16720896") Annotation( "PMID:8983065") "A protein that is a translation product of the human CD34 gene or a 1:1 ortholog thereof. It is a leukocyte membrane protein expressed specifically by lymphohematopoietic progenitor cells. It contains a single-pass transmembrane domain and that show distinct expression on early hematopoietic precursors and vascular-associated tissue. Acts as a scaffold that presents selectin carbohydrate ligands in a clustered, tissue specific manner to allow for higher avidity interactions between leukocytes and endothelial cells during the inflammatory process. In common with related sialomucins (endoglycan and podocalyxin), the extracellular region is dominated by an N-terminal mucin-like domain, which is densely substituted with sialylated O-linked carbohydrates. The mucin-like region is followed by a cysteine-containing and presumably globular domain. This domain may fold into an immunoglobulin-like structure as the positions of 2 of the cysteines are conserved in the C2 set of the immunoglobulin superfamily. The cytoplasmic domain is around 73-76 residues long and highly conserved.") -AnnotationAssertion( "PIRSF:PIRSF028749") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "CD34") -AnnotationAssertion( "hematopoietic progenitor cell antigen CD34") -AnnotationAssertion( "protein") -AnnotationAssertion( "PR:000001003") -AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") -AnnotationAssertion(rdfs:label "CD34 molecule") -SubClassOf( ) - -# Class: (CD4 molecule) - -AnnotationAssertion(Annotation( "PMID:15326605") "A protein that is a translation product of the human CD4 gene or a 1:1 ortholog thereof. CD4 is an accessory protein for MHC class-II antigen/T-cell receptor interaction. It is the primary receptor for HIV-1. CD4 has four immunoglobulin-like domains in its extracellular region that share the same structure, but can differ in sequence.") -AnnotationAssertion( "PIRSF:PIRSF001977") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "CD4") -AnnotationAssertion( "T-cell differentiation antigen L3T4") -AnnotationAssertion( "T-cell surface antigen T4/Leu-3") -AnnotationAssertion( "T-cell surface glycoprotein CD4") -AnnotationAssertion( "protein") -AnnotationAssertion( "PR:000001004") -AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") -AnnotationAssertion(rdfs:label "CD4 molecule") -SubClassOf( ) - -# Class: (integrin alpha with A domain) - -AnnotationAssertion(Annotation( "PIRSF:PIRSF002497") "An integrin alpha that contains an A domain. A hallmark of this class is the presence of a von Willebrand factor type A domain (Pfam:PF00092) (I-domain) of approximately 200 amino acid residues at the N terminus, which confers divalent cation binding properties. Unlike other integrin alpha proteins, they do not undergo proteolytic cleavage.") -AnnotationAssertion( "PIRSF:PIRSF002497") -AnnotationAssertion( "integrin alpha with I domain") -AnnotationAssertion( "protein") -AnnotationAssertion( "PR:000001005") -AnnotationAssertion(rdfs:comment "Category=family.") -AnnotationAssertion(rdfs:label "integrin alpha with A domain") -SubClassOf( ) - -# Class: (receptor-type tyrosine-protein phosphatase C) - -AnnotationAssertion(Annotation( "PMID:1351092") Annotation( "PRO:CNA") "A protein that is a translation product of the human PTPRC gene or a 1:1 ortholog thereof. It is composed of an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic protein-tyrosine phosphatase domains. Contains 1 to 3 copies of the Fibronectin type III domain (Pfam:PF00041) followed by two copies of the Protein-tyrosine phosphatase (Pfam:PF00102) domain. Receptor-type tyrosine-protein phosphatase C (CD45) regulates signal transduction and lymphocyte activation by specific association with receptor molecules on T and B cells. Multiple isoforms of CD45 (180-235 kDa) can be generated asa result of alternative splicing of three variable exons 4(A), 5(B) and 6(C), encoding sequences at the N-terminal extracellular domain of the molecule.") -AnnotationAssertion(Annotation( "PRO:DNx") "T200") -AnnotationAssertion( "IUPHARobj:1852") -AnnotationAssertion( "PIRSF:PIRSF002004") -AnnotationAssertion( "L-CA") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "PTPRC") -AnnotationAssertion( "leukocyte common antigen") -AnnotationAssertion( "ly-5") -AnnotationAssertion( "lymphocyte antigen 5") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( ) "CD45") -AnnotationAssertion( "PR:000001006") -AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") -AnnotationAssertion(rdfs:label "receptor-type tyrosine-protein phosphatase C") -AnnotationAssertion( ) -SubClassOf( ) - -# Class: (integrin alpha-M) - -AnnotationAssertion(Annotation( "UniProtKB:P11215") "An integrin alpha with A domain that is a translation product of the human ITGAM gene or a 1:1 ortholog thereof. They constitute subunits of the integrin alpha-M/beta-2 receptor. This receptor is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is also a receptor for fibrinogen, factor X and ICAM1.") -AnnotationAssertion( "IUPHARobj:2452") -AnnotationAssertion( "CD11 antigen-like family member B") -AnnotationAssertion( "CD11b") -AnnotationAssertion( "CR-3 alpha chain") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "ITGAM") -AnnotationAssertion( "cell surface glycoprotein MAC-1 subunit alpha") -AnnotationAssertion( "leukocyte adhesion receptor MO1") -AnnotationAssertion( "neutrophil adherence receptor") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( ) "CD11B") -AnnotationAssertion(Annotation( ) "CR3A") -AnnotationAssertion( "PR:000001012") -AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") -AnnotationAssertion(rdfs:label "integrin alpha-M") -AnnotationAssertion( ) -SubClassOf( ) - -# Class: (integrin alpha-X) - -AnnotationAssertion(Annotation( "UniProtKB:P20702") "An integrin alpha with A domain that is a translation product of the human ITGAX gene or a 1:1 ortholog thereof. Integrin alpha-X complexed with beta-2 is a receptor for fibrinogen. It recognizes the sequence GPR in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis.") -AnnotationAssertion( "IUPHARobj:2454") -AnnotationAssertion( "CD11 antigen-like family member C") -AnnotationAssertion( "CD11c") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "ITGAX") -AnnotationAssertion( "Leu M5") -AnnotationAssertion( "leukocyte adhesion glycoprotein p150,95 alpha chain") -AnnotationAssertion( "leukocyte adhesion receptor p150,95") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( ) "CD11C") -AnnotationAssertion( "PR:000001013") -AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") -AnnotationAssertion(rdfs:label "integrin alpha-X") -AnnotationAssertion( ) -SubClassOf( ) - -# Class: (receptor-type tyrosine-protein phosphatase C isoform CD45RABC) - -AnnotationAssertion(Annotation( "PMID:1351092") Annotation( "PRO:CNA") Annotation( "PRO:DAN") "A receptor-type tyrosine-protein phosphatase C that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P08575-3 or a 1:1 ortholog thereof.") -AnnotationAssertion( "CD45RABC") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "PTPRC/iso:CD45RABC") -AnnotationAssertion( "protein") -AnnotationAssertion( "B220") -AnnotationAssertion( "CD45R") -AnnotationAssertion( "PR:000001014") -AnnotationAssertion(rdfs:comment "Category=sequence. Requested by=CL. Note: This isoform includes the region encoded by the variable exons 4(A), 5(B), and 6(C).") -AnnotationAssertion(rdfs:label "receptor-type tyrosine-protein phosphatase C isoform CD45RABC") -AnnotationAssertion( ) -SubClassOf( ) - -# Class: (receptor-type tyrosine-protein phosphatase C isoform CD45RA) - -AnnotationAssertion(Annotation( "PMID:1351092") Annotation( "PRO:CNA") Annotation( "PRO:DAN") "A receptor-type tyrosine-protein phosphatase C isoform CD45R that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P08575-8 or a 1:1 ortholog thereof.") -AnnotationAssertion( "CD45RA") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "PTPRC/iso:CD45RA") -AnnotationAssertion( "protein") -AnnotationAssertion( "PR:000001015") -AnnotationAssertion(rdfs:comment "Category=sequence. Requested by=CL. Note: This isoform includes the region encoded by the variable exon 4(A), and lacks the region encoded by exons 5(B) and 6(C).") -AnnotationAssertion(rdfs:label "receptor-type tyrosine-protein phosphatase C isoform CD45RA") -AnnotationAssertion( ) -SubClassOf( ) - -# Class: (CD3 subunit with immunoglobulin domain) - -AnnotationAssertion(Annotation( "PMID:16473826") Annotation( "PMID:1724736") "A protein that has a core domain composition consisting of an extracellular N-terminal domain that adopts an immunoglobulin fold, a transmembrane domain, and an intracellular C-terminal domain with a single copy of the Immunoreceptor tyrosine-based activation motif (Pfam:PF02189) (ITAM). It constitutes the invariant subunit of the T cell antigen receptor (TCR). TCR is a surface receptor on T cells responsible for recognizing MHC-restricted antigens and initiating the cellular immune response.") -AnnotationAssertion( "PIRSF:PIRSF001993") -AnnotationAssertion( "CD3 subunit with Ig-like domain") -AnnotationAssertion( "protein") -AnnotationAssertion( "PR:000001018") -AnnotationAssertion(rdfs:comment "Category=family.") -AnnotationAssertion(rdfs:label "CD3 subunit with immunoglobulin domain") -SubClassOf( ) - -# Class: (CD3 epsilon) - -AnnotationAssertion(Annotation( "PRO:CNA") "A CD3 subunit with immunoglobulin domain that is a translation product of the human CD3E gene or a 1:1 ortholog thereof.") -AnnotationAssertion( "IUPHARobj:2742") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "CD3E") -AnnotationAssertion( "CD3e") -AnnotationAssertion( "T-cell surface antigen T3/Leu-4 epsilon chain") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( ) "T3E") -AnnotationAssertion( "PR:000001020") -AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") -AnnotationAssertion(rdfs:label "CD3 epsilon") -SubClassOf( ) - -# Class: (neural cell adhesion molecule) - -AnnotationAssertion(Annotation( "PRO:CNA") "A protein with a domain composition consisting of a large extracellular domain, including five Ig-like C2-type domains followed by two copies of the Fibronectin type-III domain (Pfam:PF00041), a single-pass transmembrane domain and a short cytoplasmic C-terminal domain.") -AnnotationAssertion( "PIRSF:PIRSF002507") -AnnotationAssertion( "protein") -AnnotationAssertion( "PR:000001022") -AnnotationAssertion(rdfs:comment "Category=family.") -AnnotationAssertion(rdfs:label "neural cell adhesion molecule") -SubClassOf( ) - -# Class: (neural cell adhesion molecule NCAM) - -AnnotationAssertion(Annotation( "PMID:17975827") "A neural cell adhesion molecule that is involved in neuronal development, synaptic plasticity, and regeneration.") -AnnotationAssertion( "PIRSF:PIRSF501037") -AnnotationAssertion( "protein") -AnnotationAssertion( "PR:000001023") -AnnotationAssertion(rdfs:comment "Category=family.") -AnnotationAssertion(rdfs:label "neural cell adhesion molecule NCAM") -SubClassOf( ) - -# Class: (neural cell adhesion molecule 1) - -AnnotationAssertion(Annotation( "PRO:CNA") "A neural cell adhesion molecule NCAM that is a translation product of the human NCAM1 gene or a 1:1 ortholog thereof.") -AnnotationAssertion( "IUPHARobj:2769") -AnnotationAssertion( "CD56") -AnnotationAssertion( "N-CAM-1") -AnnotationAssertion( "NCAM-1") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "NCAM1") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( ) "NCAM") -AnnotationAssertion( "PR:000001024") -AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") -AnnotationAssertion(rdfs:label "neural cell adhesion molecule 1") -AnnotationAssertion( ) -SubClassOf( ) - -# Class: (CD2 molecule) - -AnnotationAssertion(Annotation( "PRO:CNA") "A protein that is a translation product of the human CD2 gene or a 1:1 ortholog thereof.") -AnnotationAssertion( "IUPHARobj:2600") -AnnotationAssertion( "PIRSF:PIRSF001984") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "CD2") -AnnotationAssertion( "LFA-2") -AnnotationAssertion( "LFA-3 receptor") -AnnotationAssertion( "T-cell surface antigen CD2") -AnnotationAssertion( "T-cell surface antigen T11/Leu-5") -AnnotationAssertion( "T-cell surface glycoprotein CD2") -AnnotationAssertion( "erythrocyte receptor") -AnnotationAssertion( "ly-37") -AnnotationAssertion( "lymphocyte antigen 37") -AnnotationAssertion( "rosette receptor") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( ) "SRBC") -AnnotationAssertion( "PR:000001083") -AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") -AnnotationAssertion(rdfs:label "CD2 molecule") -SubClassOf( ) - -# Class: (T-cell surface glycoprotein CD8 alpha chain) - -AnnotationAssertion(Annotation( "PMID:11114424") Annotation( "PRO:CNA") Annotation( "Wikipedia:CD8") "A protein that is a translation product of the human CD8A gene or a 1:1 ortholog thereof. CD8 is a transmembrane that is a co-receptor for MHC class-I antigen/T-cell receptor interaction. The most common form of CD8 is composed of a CD8 alpha and a CD8 beta chain.") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "CD8A") -AnnotationAssertion( "CD8a") -AnnotationAssertion( "T-cell surface glycoprotein Lyt-2") -AnnotationAssertion( "T-lymphocyte differentiation antigen T8/Leu-2") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( ) "Lyt-2") -AnnotationAssertion(Annotation( ) "Lyt2") -AnnotationAssertion(Annotation( ) "MAL") -AnnotationAssertion( "PR:000001084") -AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") -AnnotationAssertion(rdfs:label "T-cell surface glycoprotein CD8 alpha chain") -AnnotationAssertion( ) -SubClassOf( ) - -# Class: (rhodopsin-like G-protein coupled receptor) - -AnnotationAssertion(Annotation( "PMID:12761335") Annotation( "PRO:DAN") Annotation( "PRO:WCB") "A G-protein coupled receptor that contains the 7 transmembrane receptor (rhodopsin family) domain (Pfam:PF00001), which includes 7 transmembrane helices (TMI-TM7) with 3 intracellular loops (IL1-IL3) and 3 extracellular loops (EL1-EL3) between the helices. The amino-terminal region is extracellular and the carboxyl-terminal region is intracellular. Rhodopsin-like G-protein coupled receptors (GPCRs) are unique among the several classes of GPCRs in that most have a very short amino-terminal segment and several characteristic sequence motifs, particularly NSxxNPxxY in TM7 and D/E-R-Y/F between TM3 and loop IL2. Most bind their ligands within a cavity between the TM regions.") -AnnotationAssertion( "IUPHAR:GPCRListForward?class=A") -AnnotationAssertion( "PIRSF:PIRSF800006") -AnnotationAssertion(Annotation( "PMID:15914470") "class 1 G-protein coupled receptor") -AnnotationAssertion(Annotation( "IUPHAR:GPCRListForward?class=A") "class A G-protein coupled receptor") -AnnotationAssertion(Annotation( "PRO:DAN") Annotation( ) "fam:rhodopsin") -AnnotationAssertion( "protein") -AnnotationAssertion( "PR:000001094") -AnnotationAssertion(rdfs:comment "Category=family. Classification based on GRAFS system. [PMID:12761335]") -AnnotationAssertion(rdfs:label "rhodopsin-like G-protein coupled receptor") -SubClassOf( ) - -# Class: (chemokine receptor) - -AnnotationAssertion(Annotation( "PMID:12037138") Annotation( "PRO:WCB") Annotation( "PRO:XQ") "A rhodopsin-like G-protein coupled receptor that in active form binds to one or more chemokines.") -AnnotationAssertion( "IUPHARfam:14") -AnnotationAssertion( "PIRSF:PIRSF038545") -AnnotationAssertion( "protein") -AnnotationAssertion( "PR:000001128") -AnnotationAssertion(rdfs:comment "Category=family. Note: Only those that have been unequivocally shown to activate a G-protein coupled signaling pathway appear on the official IUPHAR list.") -AnnotationAssertion(rdfs:label "chemokine receptor") -SubClassOf( ) - -# Class: (C-C chemokine receptor type 2) - -AnnotationAssertion(Annotation( "PMID:12037138") Annotation( "PRO:WCB") "A chemokine receptor that is a translation product of the human CCR2 gene or a 1:1 ortholog thereof. The preferred ligands include CCL2, CCL7, CCL8, CCL13.") -AnnotationAssertion( "IUPHARobj:59") -AnnotationAssertion( "C-C CKR-2") -AnnotationAssertion( "CC-CKR-2") -AnnotationAssertion( "CCR-2") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "CCR2") -AnnotationAssertion( "CD192") -AnnotationAssertion( "JE/FIC receptor") -AnnotationAssertion( "MCP-1 receptor") -AnnotationAssertion( "MCP-1-R") -AnnotationAssertion( "chemokine receptor CCR2") -AnnotationAssertion( "monocyte chemoattractant protein 1 receptor") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( ) "CMKBR2") -AnnotationAssertion( "PR:000001199") -AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") -AnnotationAssertion(rdfs:label "C-C chemokine receptor type 2") -AnnotationAssertion( ) -SubClassOf( ) - -# Class: (CX3C chemokine receptor 1) - -AnnotationAssertion(Annotation( "PMID:12037138") Annotation( "PRO:WCB") "A chemokine receptor that is a translation product of the human CX3CR1 gene or a 1:1 ortholog thereof. The preferred ligand is CX3CL1.") -AnnotationAssertion( "IUPHARobj:74") -AnnotationAssertion( "PIRSF:PIRSF501025") -AnnotationAssertion( "C-X3-C CKR-1") -AnnotationAssertion( "CMK-BRL-1") -AnnotationAssertion( "CMK-BRL1") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "CX3CR1") -AnnotationAssertion( "G-protein coupled receptor 13") -AnnotationAssertion( "V28") -AnnotationAssertion( "beta chemokine receptor-like 1") -AnnotationAssertion( "chemokine receptor CX3CR1") -AnnotationAssertion( "fractalkine receptor") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( ) "CMKBRL1") -AnnotationAssertion(Annotation( ) "GPR13") -AnnotationAssertion( "PR:000001206") -AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") -AnnotationAssertion(rdfs:label "CX3C chemokine receptor 1") -AnnotationAssertion( ) -SubClassOf( ) - -# Class: (ADP-ribosyl cyclase) - -AnnotationAssertion(Annotation( "PRO:WCB") "A protein that contains the ADP-ribosyl cyclase domain (Pfam:PF02267).") -AnnotationAssertion( "PIRSF:PIRSF005736") -AnnotationAssertion( "protein") -AnnotationAssertion( "PR:000001281") -AnnotationAssertion(rdfs:comment "Category=family.") -AnnotationAssertion(rdfs:label "ADP-ribosyl cyclase") -SubClassOf( ) - -# Class: (membrane-spanning 4-domains subfamily A member 1) - -AnnotationAssertion(Annotation( "PRO:WCB") "A protein that is a translation product of the human MS4A1 gene or a 1:1 ortholog thereof.") -AnnotationAssertion( "IUPHARobj:2628") -AnnotationAssertion( "PIRSF:PIRSF001995") -AnnotationAssertion( "B-cell differentiation antigen Ly-44") -AnnotationAssertion( "B-cell surface antigen CD20") -AnnotationAssertion( "B-lymphocyte antigen CD20") -AnnotationAssertion( "B-lymphocyte surface antigen B1") -AnnotationAssertion( "Bp35") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "MS4A1") -AnnotationAssertion( "leukocyte surface antigen Leu-16") -AnnotationAssertion( "lymphocyte antigen 44") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( ) "CD20") -AnnotationAssertion(Annotation( ) "Ly-44") -AnnotationAssertion(Annotation( ) "Ms4a2") -AnnotationAssertion( "PR:000001289") -AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") -AnnotationAssertion(rdfs:label "membrane-spanning 4-domains subfamily A member 1") -SubClassOf( ) - -# Class: (C-type lectin domain family 4 member K) - -AnnotationAssertion(Annotation( "PRO:WCB") "A protein that is a translation product of the human CD207 gene or a 1:1 ortholog thereof.") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "CD207") -AnnotationAssertion( "langerin") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( ) "CLEC4K") -AnnotationAssertion( "PR:000001293") -AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") -AnnotationAssertion(rdfs:label "C-type lectin domain family 4 member K") -AnnotationAssertion( ) -SubClassOf( ) - -# Class: (CD44 molecule) - -AnnotationAssertion(Annotation( "PRO:WCB") "A protein that is a translation product of the human CD44 gene or a 1:1 ortholog thereof.") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "CD44") -AnnotationAssertion( "CD44 antigen") -AnnotationAssertion( "CDw44") -AnnotationAssertion( "ECMR-III") -AnnotationAssertion( "GP90 lymphocyte homing/adhesion receptor") -AnnotationAssertion( "HUTCH-I") -AnnotationAssertion( "PGP-1") -AnnotationAssertion( "epican") -AnnotationAssertion( "extracellular matrix receptor III") -AnnotationAssertion( "heparan sulfate proteoglycan") -AnnotationAssertion( "hermes antigen") -AnnotationAssertion( "hyaluronate receptor") -AnnotationAssertion( "ly-24") -AnnotationAssertion( "lymphocyte antigen 24") -AnnotationAssertion( "phagocytic glycoprotein 1") -AnnotationAssertion( "phagocytic glycoprotein I") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( ) "LHR") -AnnotationAssertion(Annotation( ) "MDU2") -AnnotationAssertion(Annotation( ) "MDU3") -AnnotationAssertion(Annotation( ) "MIC4") -AnnotationAssertion( "PGP-I") -AnnotationAssertion( "PR:000001307") -AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") -AnnotationAssertion(rdfs:label "CD44 molecule") -SubClassOf( ) - -# Class: (CD48 molecule) - -AnnotationAssertion(Annotation( "PRO:WCB") "A protein that is a translation product of the human CD48 gene or a 1:1 ortholog thereof.") -AnnotationAssertion( "PIRSF:PIRSF001973") -AnnotationAssertion( "B-lymphocyte activation marker BLAST-1") -AnnotationAssertion( "BCM1 surface antigen") -AnnotationAssertion( "BLAST-1") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "CD48") -AnnotationAssertion( "CD48 antigen") -AnnotationAssertion( "HM48-1") -AnnotationAssertion( "MRC OX-45 surface antigen") -AnnotationAssertion( "SLAM family member 2") -AnnotationAssertion( "SLAMF2") -AnnotationAssertion( "TCT.1") -AnnotationAssertion( "leukocyte antigen MEM-102") -AnnotationAssertion( "sgp-60") -AnnotationAssertion( "signaling lymphocytic activation molecule 2") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( ) "BCM1") -AnnotationAssertion(Annotation( ) "BLAST1") -AnnotationAssertion(Annotation( ) "Bcm-1") -AnnotationAssertion( "PR:000001308") -AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") -AnnotationAssertion(rdfs:label "CD48 molecule") -SubClassOf( ) - -# Class: (cadherin) - -AnnotationAssertion(Annotation( "PRO:WCB") "A protein that has a core domain structure of signal sequence, propeptide, five Cadherin domains (Pfam:PF00028), a transmembrane region, and a Cadherin cytoplasmic region (Pfam:PF01049). Cadherins function as adhesion molecules that mediate Ca2+-dependent cell-cell adhesion in solid tissues.") -AnnotationAssertion( "PIRSF:PIRSF002504") -AnnotationAssertion( "protein") -AnnotationAssertion( "PR:000001327") -AnnotationAssertion(rdfs:comment "Category=family.") -AnnotationAssertion(rdfs:label "cadherin") -SubClassOf( ) - -# Class: (carcinoembryonic antigen-related cell adhesion molecule 8) - -AnnotationAssertion(Annotation( "PRO:CNA") "A protein that is a translation product of the human CEACAM8 gene or a 1:1 ortholog thereof.") -AnnotationAssertion( "CD66b") -AnnotationAssertion( "CD67 antigen") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "CEACAM8") -AnnotationAssertion( "carcinoembryonic antigen CGM6") -AnnotationAssertion( "non-specific cross-reacting antigen NCA-95") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( ) "CGM6") -AnnotationAssertion( "PR:000001332") -AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") -AnnotationAssertion(rdfs:label "carcinoembryonic antigen-related cell adhesion molecule 8") -AnnotationAssertion( ) -SubClassOf( ) - -# Class: (complement receptor type 2) - -AnnotationAssertion(Annotation( "PRO:WCB") "A protein that is a translation product of the human CR2 gene or a 1:1 ortholog thereof.") -AnnotationAssertion( "PIRSF:PIRSF002484") -AnnotationAssertion( "CD21") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "CR2") -AnnotationAssertion( "Cr2") -AnnotationAssertion( "EBV receptor") -AnnotationAssertion( "complement C3d receptor") -AnnotationAssertion( "epstein-Barr virus receptor") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( ) "C3DR") -AnnotationAssertion( "PR:000001338") -AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") -AnnotationAssertion(rdfs:label "complement receptor type 2") -AnnotationAssertion( ) -SubClassOf( ) - -# Class: (endoglin) - -AnnotationAssertion(Annotation( "PRO:CNA") "A protein that is a translation product of the human ENG gene or a 1:1 ortholog thereof.") -AnnotationAssertion( "IUPHARobj:2895") -AnnotationAssertion( "PIRSF:PIRSF038746") -AnnotationAssertion( "CD105") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "ENG") -AnnotationAssertion( "cell surface MJ7/18 antigen") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( ) "END") -AnnotationAssertion(Annotation( ) "Edg") -AnnotationAssertion( "PR:000001345") -AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") -AnnotationAssertion(rdfs:label "endoglin") -AnnotationAssertion( ) -SubClassOf( ) - -# Class: (glycophorin) - -AnnotationAssertion(Annotation( "InterPro:IPR001195") Annotation( "PRO:CNA") "A protein that contains an extracellular Glycophorin A domain (Pfam:PF01102), followed by a single-pass transmembrane region and a small intracellular domain. A protein that is an integral protein of the red cell membrane. Proteins in this class are responsible for the molecular basis of the blood group antigens, surface markers on the outside of the red blood cell membrane.") -AnnotationAssertion( "PIRSF:PIRSF002466") -AnnotationAssertion( "protein") -AnnotationAssertion( "PR:000001352") -AnnotationAssertion(rdfs:comment "Category=family.") -AnnotationAssertion(rdfs:label "glycophorin") -SubClassOf( ) - -# Class: (immunoglobulin gamma Fc receptor II/III/IV) - -AnnotationAssertion(Annotation( "PRO:WCB") "A protein with a core domain architecture consisting of an extracellular domain containing two copies of the Immunoglobulin domain (Pfam:PF00047), followed by a single-pass transmembrane region and a small intracellular domain. The active protein is a low affinity receptor for immunoglobulin gamma chain Fc region. Human II-a, II-b, and II-c represent a recent gene expansion and are equally related to mouse II, III, and IV. Human III-A and III-B are closely related and closer to mouse IV than to mouse III.") -AnnotationAssertion( "PIRSF:PIRSF001980") -AnnotationAssertion( "protein") -AnnotationAssertion( "PR:000001355") -AnnotationAssertion(rdfs:comment "Category=family.") -AnnotationAssertion(rdfs:label "immunoglobulin gamma Fc receptor II/III/IV") -SubClassOf( ) - -# Class: (interleukin-2 receptor subunit alpha) - -AnnotationAssertion(Annotation( "PRO:CNA") "A protein that is a translation product of the human IL2RA gene or a 1:1 ortholog thereof.") -AnnotationAssertion(Annotation( "PRO:DNx") "p55") -AnnotationAssertion( "IUPHARobj:1695") -AnnotationAssertion( "PIRSF:PIRSF001954") -AnnotationAssertion( "CD25") -AnnotationAssertion( "IL-2 receptor subunit alpha") -AnnotationAssertion( "IL-2-RA") -AnnotationAssertion( "IL-2R subunit alpha") -AnnotationAssertion( "IL2-RA") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "IL2RA") -AnnotationAssertion( "TAC antigen") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( ) "Il2r") -AnnotationAssertion( "PR:000001380") -AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") -AnnotationAssertion(rdfs:label "interleukin-2 receptor subunit alpha") -AnnotationAssertion( ) -SubClassOf( ) - -# Class: (ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1) - -AnnotationAssertion(Annotation( "PRO:WCB") "An ADP-ribosyl cyclase that is a translation product of the human CD38 gene or a 1:1 ortholog thereof.") -AnnotationAssertion( "IUPHARobj:2766") -AnnotationAssertion( "2'-phospho-ADP-ribosyl cyclase") -AnnotationAssertion( "2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase") -AnnotationAssertion( "2'-phospho-cyclic-ADP-ribose transferase") -AnnotationAssertion( "ADP-ribosyl cyclase 1") -AnnotationAssertion( "ADPRC 1") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "CD38") -AnnotationAssertion( "I-19") -AnnotationAssertion( "NIM-R5 antigen") -AnnotationAssertion( "T10") -AnnotationAssertion( "cADPr hydrolase 1") -AnnotationAssertion( "cyclic ADP-ribose hydrolase 1") -AnnotationAssertion( "protein") -AnnotationAssertion( "PR:000001408") -AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") -AnnotationAssertion(rdfs:label "ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1") -AnnotationAssertion( ) -SubClassOf( ) - -# Class: (cadherin-5) - -AnnotationAssertion(Annotation( "PRO:WCB") "A cadherin that is a translation product of the human CDH5 gene or a 1:1 ortholog thereof.") -AnnotationAssertion( "7B4 antigen") -AnnotationAssertion( "CD144") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "CDH5") -AnnotationAssertion( "VE-cadherin") -AnnotationAssertion( "vascular endothelial cadherin") -AnnotationAssertion( "protein") -AnnotationAssertion( "PR:000001444") -AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") -AnnotationAssertion(rdfs:label "cadherin-5") -AnnotationAssertion( ) -SubClassOf( ) - -# Class: (glycophorin-A) - -AnnotationAssertion(Annotation( "InterPro:IPR001195") Annotation( "PRO:CNA") "A glycophorin that is a translation product of the human GYPA gene or a 1:1 ortholog thereof. It is the major sialoglycoprotein of the erythrocyte membrane. Structurally, glycophorin A consists of an N-terminal extracellular domain, heavily glycosylated on Ser and threonine residues, followed by a transmembrane region and a C-terminal cytoplasmic domain.") -AnnotationAssertion( "CD235a") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "GYPA") -AnnotationAssertion( "MN sialoglycoprotein") -AnnotationAssertion( "PAS-2") -AnnotationAssertion( "sialoglycoprotein alpha") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( ) "GPA") -AnnotationAssertion( "PR:000001460") -AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") -AnnotationAssertion(rdfs:label "glycophorin-A") -AnnotationAssertion( ) -SubClassOf( ) - -# Class: (low affinity immunoglobulin gamma Fc region receptor II) - -AnnotationAssertion(Annotation( "PRO:CNA") "An immunoglobulin gamma Fc receptor II/III/IV that is a translation product of the mouse Fcgr2 gene or a 1:1 ortholog thereof.") -AnnotationAssertion(Annotation( "PRO:DNx") "CD32") -AnnotationAssertion( "Fc gamma receptor IIB") -AnnotationAssertion( "Fc-gamma RII") -AnnotationAssertion( "Fc-gamma-RIIB") -AnnotationAssertion( "FcRII") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "Fcgr2") -AnnotationAssertion( "IgG Fc receptor II beta") -AnnotationAssertion( "ly-17") -AnnotationAssertion( "lymphocyte antigen 17") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( ) "Fcgr2b") -AnnotationAssertion( "PR:000001479") -AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") -AnnotationAssertion(rdfs:label "low affinity immunoglobulin gamma Fc region receptor II") -SubClassOf( ) - -# Class: (low affinity immunoglobulin gamma Fc region receptor II-b) - -AnnotationAssertion(Annotation( "PRO:CNA") "An immunoglobulin gamma Fc receptor II/III/IV that is a translation product of the human FCGR2B gene or a 1:1 ortholog thereof.") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "CD32") -AnnotationAssertion(Annotation( "PRO:DNx") "CDw32") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "FCGR2B") -AnnotationAssertion( "Fc-gamma RII-b") -AnnotationAssertion( "Fc-gamma-RIIb") -AnnotationAssertion( "FcRII-b") -AnnotationAssertion( "IgG Fc receptor II-b") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( ) "FCG2") -AnnotationAssertion(Annotation( ) "IGFR2") -AnnotationAssertion( "PR:000001481") -AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") -AnnotationAssertion(rdfs:label "low affinity immunoglobulin gamma Fc region receptor II-b") -AnnotationAssertion( ) -SubClassOf( ) - -# Class: (low affinity immunoglobulin gamma Fc region receptor III) - -AnnotationAssertion(Annotation( "PRO:CNA") "An immunoglobulin gamma Fc receptor II/III/IV that is a translation product of the mouse Fcgr3 gene or a 1:1 ortholog thereof.") -AnnotationAssertion( "CD16") -AnnotationAssertion( "Fc-gamma RIII") -AnnotationAssertion( "FcRIII") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "Fcgr3") -AnnotationAssertion( "IgG Fc receptor III") -AnnotationAssertion( "protein") -AnnotationAssertion( "PR:000001483") -AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") -AnnotationAssertion(rdfs:label "low affinity immunoglobulin gamma Fc region receptor III") -SubClassOf( ) - -# Class: (transcription factor NF-kappa-B subunit) - -AnnotationAssertion(Annotation( "PRO:JAN") "A protein that has a core domain composition consisting of a Rel homology domain (RHD) (Pfam:PF00554), an IPT/TIG domain (Pfam:PF01833), six copies of the Ankyrin repeat (Pfam:PF00023), a Death domain (Pfam:PF00531) and a C-terminal PEST region.") -AnnotationAssertion( "PIRSF:PIRSF036310") -AnnotationAssertion( "protein") -AnnotationAssertion( "transcription factor NF-kappa-B") -AnnotationAssertion( "PR:000001753") -AnnotationAssertion(rdfs:comment "Category=family.") -AnnotationAssertion(rdfs:label "transcription factor NF-kappa-B subunit") -SubClassOf( ) - -# Class: (prominin) - -AnnotationAssertion(Annotation( "InterPro:IPR008795") Annotation( "PMID:11467842") "A protein with core architecture consisting of one Prominin (Pfam:PF05478) domain. The prominins are an emerging family of proteins that, among the multispan membrane proteins, display a novel topology. Mouse and human prominin and prominin-like 1 are predicted to contain five membrane spanning domains, with an N-terminal domain exposed to the extracellular space followed by four, alternating small cytoplasmic and large extracellular, loops and a cytoplasmic C-terminal domain.") -AnnotationAssertion( "PANTHER:PTHR22730") -AnnotationAssertion( "PIRSF:PIRSF017831") -AnnotationAssertion( "protein") -AnnotationAssertion( "PR:000001785") -AnnotationAssertion(rdfs:comment "Category=family.") -AnnotationAssertion(rdfs:label "prominin") -SubClassOf( ) - -# Class: (prominin-1) - -AnnotationAssertion(Annotation( "PRO:CNA") "A prominin that is a translation product of the human PROM1 gene or a 1:1 ortholog thereof.") -AnnotationAssertion( "CD133") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "PROM1") -AnnotationAssertion( "antigen AC133") -AnnotationAssertion( "antigen AC133 homolog") -AnnotationAssertion( "prominin-like protein 1") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( ) "MSTP061") -AnnotationAssertion(Annotation( ) "PROML1") -AnnotationAssertion(Annotation( ) "Prom") -AnnotationAssertion( "PR:000001786") -AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") -AnnotationAssertion(rdfs:label "prominin-1") -AnnotationAssertion( ) -SubClassOf( ) - -# Class: (CD59-like glycoprotein) - -AnnotationAssertion(Annotation( "PRO:WCB") "A protein that is a translation product of the human CD59 gene, a 1:1 ortholog thereof, or pro-orthologs thereof.") -AnnotationAssertion( "PIRSF:PIRSF038782") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "CD59-like") -AnnotationAssertion( "protein") -AnnotationAssertion( "PR:000001809") -AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL. Pro-orthology refers to, in this case, after-speciation gene duplication in the non-human species (aka 1:many orthology). This gene is present as a single copy in human and has undergone a lineage-specific duplication in mouse. CD59 antigen has a core architecture consisting of one UPAR/Ly-6 domain (Pfam:PF00021), a small domain of about 70 amino acids and containing 5 conserved disulfide bonds. It is both N- and O-glycosylated and is a GPI-anchored protein that releases soluble forms in some tissues.") -AnnotationAssertion(rdfs:label "CD59-like glycoprotein") -SubClassOf( ) - -# Class: (CSF-1/PDGF receptor-type tyrosine-protein kinase) - -AnnotationAssertion(Annotation( "PRO:WCB") "A protein with core architecture consisting of asignal sequence, 5 Ig-like domains, followed by a transmembrane sequence, followed by a Protein tyrosine kinase domain (Pfam:PF07714). However, only 1-3 of the Ig domains are detected by the Pfam HMMs in most of the sequences. Pfam:PF00047 is most common, but other members of the Ig domain clan, Pfam:PF07679 and Pfam:PF07686 can be identified instead. The fourth Ig domain lacks the disulfide-bonded cysteines.") -AnnotationAssertion( "PIRSF:PIRSF000615") -AnnotationAssertion( "protein") -AnnotationAssertion( "PR:000001810") -AnnotationAssertion(rdfs:comment "Category=family.") -AnnotationAssertion(rdfs:label "CSF-1/PDGF receptor-type tyrosine-protein kinase") -SubClassOf( ) - -# Class: (SLAM family member 1) - -AnnotationAssertion(Annotation( "PRO:WCB") "A protein that is a translation product of the human SLAMF1 gene or a 1:1 ortholog thereof.") -AnnotationAssertion( "CD150") -AnnotationAssertion( "CDw150") -AnnotationAssertion( "IPO-3") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "SLAMF1") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( ) "SLAM") -AnnotationAssertion( "PR:000001833") -AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") -AnnotationAssertion(rdfs:label "SLAM family member 1") -SubClassOf( ) - -# Class: (CD7 molecule) - -AnnotationAssertion(Annotation( "PRO:WCB") "A protein that is a translation product of the human CD7 gene or a 1:1 ortholog thereof.") -AnnotationAssertion( "PIRSF:PIRSF038791") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "CD7") -AnnotationAssertion( "GP40") -AnnotationAssertion( "T-cell antigen CD7") -AnnotationAssertion( "T-cell leukemia antigen") -AnnotationAssertion( "T-cell surface antigen Leu-9") -AnnotationAssertion( "TP41") -AnnotationAssertion( "protein") -AnnotationAssertion( "PR:000001836") -AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") -AnnotationAssertion(rdfs:label "CD7 molecule") -SubClassOf( ) - -# Class: (T-cell surface glycoprotein CD5) - -AnnotationAssertion(Annotation( "PRO:WCB") "A protein that is a translation product of the human CD5 gene or a 1:1 ortholog thereof.") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "CD5") -AnnotationAssertion( "Lyt-1") -AnnotationAssertion( "ly-1") -AnnotationAssertion( "lymphocyte antigen 1") -AnnotationAssertion( "lymphocyte antigen T1/Leu-1") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( ) "LEU1") -AnnotationAssertion( "PR:000001839") -AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") -AnnotationAssertion(rdfs:label "T-cell surface glycoprotein CD5") -AnnotationAssertion( ) -SubClassOf( ) - -# Class: (Thy-1 membrane glycoprotein) - -AnnotationAssertion(Annotation( "PRO:WCB") "A protein that is a translation product of the human THY1 gene or a 1:1 ortholog thereof.") -AnnotationAssertion( "PIRSF:PIRSF038777") -AnnotationAssertion( "CD90") -AnnotationAssertion( "CDw90") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "THY1") -AnnotationAssertion( "Thy-1 antigen") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( ) "Thy-1") -AnnotationAssertion( "PR:000001843") -AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") -AnnotationAssertion(rdfs:label "Thy-1 membrane glycoprotein") -AnnotationAssertion( ) -SubClassOf( ) - -# Class: (cathepsin K) - -AnnotationAssertion(Annotation( "PRO:DAN") Annotation( "PRO:WCB") "A cathepsin-like protease that is a translation product of the human CTSK gene or a 1:1 ortholog thereof.") -AnnotationAssertion( "IUPHARobj:2350") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "CTSK") -AnnotationAssertion( "cathepsin O2") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( ) "CTSO") -AnnotationAssertion(Annotation( ) "CTSO2") -AnnotationAssertion( "cathepsin O") -AnnotationAssertion( "cathepsin X") -AnnotationAssertion( "PR:000001850") -AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") -AnnotationAssertion(rdfs:label "cathepsin K") -AnnotationAssertion( ) -SubClassOf( ) - -# Class: (immunoglobulin iota chain) - -AnnotationAssertion(Annotation( "PRO:WCB") "A protein that is a translation product of the human VPREB1 gene or a 1:1 ortholog thereof. The gene is recently and independently duplicated in mouse and rabbit, giving rise to very closely related VPREB2 genes in those species. The protein associates with the Ig-mu chain to form a molecular complex that is expressed only on the surface of pre-B-cells.") -AnnotationAssertion( "PIRSF:PIRSF038787") -AnnotationAssertion( "CD179 antigen-like family member A") -AnnotationAssertion( "CD179a") -AnnotationAssertion( "V(pre)B protein") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "VPREB1") -AnnotationAssertion( "VpreB protein") -AnnotationAssertion( "protein VPreB1") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( ) "VPREB") -AnnotationAssertion( "PR:000001858") -AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") -AnnotationAssertion(rdfs:label "immunoglobulin iota chain") -AnnotationAssertion( ) -SubClassOf( ) - -# Class: (immunoglobulin lambda-like polypeptide 1) - -AnnotationAssertion(Annotation( "PRO:WCB") "A protein that is a translation product of the human IGLL1 gene or a 1:1 ortholog thereof.") -AnnotationAssertion( "CD179 antigen-like family member B") -AnnotationAssertion( "CD179b") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "IGLL1") -AnnotationAssertion( "Ig lambda-5") -AnnotationAssertion( "immunoglobulin omega polypeptide") -AnnotationAssertion( "immunoglobulin-related protein 14.1") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( ) "IGL1") -AnnotationAssertion( "Igl-5") -AnnotationAssertion( "PR:000001859") -AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") -AnnotationAssertion(rdfs:label "immunoglobulin lambda-like polypeptide 1") -AnnotationAssertion( ) -SubClassOf( ) - -# Class: (interleukin-3 receptor class 2 alpha chain) - -AnnotationAssertion(Annotation( "PRO:WCB") "A protein that is a translation product of the human IL3RA gene or a 1:1 ortholog thereof.") -AnnotationAssertion( "IUPHARobj:1705") -AnnotationAssertion( "CD123") -AnnotationAssertion( "IL-3 receptor subunit alpha") -AnnotationAssertion( "IL-3R subunit alpha") -AnnotationAssertion( "IL-3R-alpha") -AnnotationAssertion( "IL-3RA") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "IL3RA") -AnnotationAssertion( "interleukin-3 receptor class II alpha chain") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( ) "IL3R") -AnnotationAssertion(Annotation( ) "Sut-1") -AnnotationAssertion( "PR:000001865") -AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") -AnnotationAssertion(rdfs:label "interleukin-3 receptor class 2 alpha chain") -SubClassOf( ) - -# Class: (interleukin-5 receptor subunit alpha) - -AnnotationAssertion(Annotation( "PRO:WCB") "A protein that is a translation product of the human IL5RA gene or a 1:1 ortholog thereof.") -AnnotationAssertion( "IUPHARobj:1706") -AnnotationAssertion( "PIRSF:PIRSF018419") -AnnotationAssertion( "CD125") -AnnotationAssertion( "CDw125") -AnnotationAssertion( "IL-5 receptor subunit alpha") -AnnotationAssertion( "IL-5R subunit alpha") -AnnotationAssertion( "IL-5R-alpha") -AnnotationAssertion( "IL-5RA") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "IL5RA") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( ) "IL5R") -AnnotationAssertion( "PR:000001867") -AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") -AnnotationAssertion(rdfs:label "interleukin-5 receptor subunit alpha") -AnnotationAssertion( ) -SubClassOf( ) - -# Class: (interleukin-7 receptor subunit alpha) - -AnnotationAssertion(Annotation( "PRO:WCB") "A protein that is a translation product of the human IL7R gene or a 1:1 ortholog thereof.") -AnnotationAssertion( "IUPHARobj:1698") -AnnotationAssertion( "PIRSF:PIRSF001960") -AnnotationAssertion( "CD127") -AnnotationAssertion( "CDw127") -AnnotationAssertion( "IL-7 receptor subunit alpha") -AnnotationAssertion( "IL-7R subunit alpha") -AnnotationAssertion( "IL-7R-alpha") -AnnotationAssertion( "IL-7RA") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "IL7R") -AnnotationAssertion( "protein") -AnnotationAssertion( "PR:000001869") -AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") -AnnotationAssertion(rdfs:label "interleukin-7 receptor subunit alpha") -AnnotationAssertion( ) -SubClassOf( ) - -# Class: (KLRB1-like protein) - -AnnotationAssertion(Annotation( "PRO:WCB") "A protein that is a translation product of the KLRB1 gene or its closely related paralogs (KLRB1A-F). There are lineage-specific expansions in mouse and rat.") -AnnotationAssertion( "PIRSF:PIRSF038804") -AnnotationAssertion( "protein") -AnnotationAssertion( "PR:000001874") -AnnotationAssertion(rdfs:comment "Category=family. Requested by=CL.") -AnnotationAssertion(rdfs:label "KLRB1-like protein") -SubClassOf( ) - -# Class: (leukosialin) - -AnnotationAssertion(Annotation( "PRO:WCB") "A protein that is a translation product of the human SPN gene or a 1:1 ortholog thereof.") -AnnotationAssertion( "PIRSF:PIRSF001994") -AnnotationAssertion( "B-cell differentiation antigen LP-3") -AnnotationAssertion( "GALGP") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "SPN") -AnnotationAssertion( "galactoglycoprotein") -AnnotationAssertion( "leukocyte sialoglycoprotein") -AnnotationAssertion( "ly-48") -AnnotationAssertion( "lymphocyte antigen 48") -AnnotationAssertion( "sialophorin") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( ) "CD43") -AnnotationAssertion( "PR:000001879") -AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") -AnnotationAssertion(rdfs:label "leukosialin") -AnnotationAssertion( ) -SubClassOf( ) - -# Class: (low affinity immunoglobulin epsilon Fc receptor) - -AnnotationAssertion(Annotation( "PRO:WCB") "A protein that is a translation product of the human FCER2 gene or a 1:1 ortholog thereof.") -AnnotationAssertion( "IUPHARobj:2935") -AnnotationAssertion( "PIRSF:PIRSF002426") -AnnotationAssertion( "BLAST-2") -AnnotationAssertion( "C-type lectin domain family 4 member J") -AnnotationAssertion( "CD23") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "FCER2") -AnnotationAssertion( "Fc-epsilon-RII") -AnnotationAssertion( "immunoglobulin E-binding factor") -AnnotationAssertion( "lymphocyte IgE receptor") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( ) "CD23A") -AnnotationAssertion(Annotation( ) "CLEC4J") -AnnotationAssertion(Annotation( ) "FCE2") -AnnotationAssertion(Annotation( ) "Fcer2a") -AnnotationAssertion(Annotation( ) "IGEBF") -AnnotationAssertion( "PR:000001880") -AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") -AnnotationAssertion(rdfs:label "low affinity immunoglobulin epsilon Fc receptor") -AnnotationAssertion( ) -SubClassOf( ) - -# Class: (membrane alanyl aminopeptidase-like metallopeptidase) - -AnnotationAssertion(Annotation( "PRO:WCB") "A protein with core architecture consisting of a Peptidase family M1 domain (Pfam:PF01433).") -AnnotationAssertion( "PIRSF:PIRSF005502") -AnnotationAssertion( "protein") -AnnotationAssertion( "PR:000001888") -AnnotationAssertion(rdfs:comment "Category=family.") -AnnotationAssertion(rdfs:label "membrane alanyl aminopeptidase-like metallopeptidase") -SubClassOf( ) - -# Class: (CD14 molecule) - -AnnotationAssertion(Annotation( "PRO:WCB") "A protein that is a translation product of the human CD14 gene or a 1:1 ortholog thereof.") -AnnotationAssertion( "PIRSF:PIRSF002017") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "CD14") -AnnotationAssertion( "monocyte differentiation antigen CD14") -AnnotationAssertion( "myeloid cell-specific leucine-rich glycoprotein") -AnnotationAssertion( "protein") -AnnotationAssertion( "PR:000001889") -AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") -AnnotationAssertion(rdfs:label "CD14 molecule") -SubClassOf( ) - -# Class: (CD33 molecule) - -AnnotationAssertion(Annotation( "PRO:WCB") "A protein that is a translation product of the human CD33 gene or a 1:1 ortholog thereof.") -AnnotationAssertion( "IUPHARobj:2601") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "CD33") -AnnotationAssertion( "gp67") -AnnotationAssertion( "myeloid cell surface antigen CD33") -AnnotationAssertion( "sialic acid-binding Ig-like lectin 3") -AnnotationAssertion( "siglec-3") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( ) "SIGLEC3") -AnnotationAssertion( "PR:000001892") -AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") -AnnotationAssertion(rdfs:label "CD33 molecule") -SubClassOf( ) - -# Class: (natural killer cell receptor 2B4) - -AnnotationAssertion(Annotation( "PRO:WCB") "A protein that is a translation product of the human CD244 gene or a 1:1 ortholog thereof.") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "CD244") -AnnotationAssertion( "NAIL") -AnnotationAssertion( "NK cell activation-inducing ligand") -AnnotationAssertion( "NK cell type I receptor protein 2B4") -AnnotationAssertion( "NKR2B4") -AnnotationAssertion( "SLAM family member 4") -AnnotationAssertion( "SLAMF4") -AnnotationAssertion( "non-MHC restricted killing associated") -AnnotationAssertion( "signaling lymphocytic activation molecule 4") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( ) "2B4") -AnnotationAssertion(Annotation( ) "Nmrk") -AnnotationAssertion( "PR:000001896") -AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") -AnnotationAssertion(rdfs:label "natural killer cell receptor 2B4") -AnnotationAssertion( ) -SubClassOf( ) - -# Class: (neprilysin) - -AnnotationAssertion(Annotation( "PRO:WCB") "A protein that is a translation product of the human MME gene or a 1:1 ortholog thereof.") -AnnotationAssertion( "IUPHARobj:1611") -AnnotationAssertion( "PIRSF:PIRSF501074") -AnnotationAssertion( "CALLA") -AnnotationAssertion( "CD10") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "MME") -AnnotationAssertion( "NEP") -AnnotationAssertion( "SFE") -AnnotationAssertion( "atriopeptidase") -AnnotationAssertion( "common acute lymphocytic leukemia antigen") -AnnotationAssertion( "enkephalinase") -AnnotationAssertion( "neutral endopeptidase") -AnnotationAssertion( "neutral endopeptidase 24.11") -AnnotationAssertion( "skin fibroblast elastase") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( ) "EPN") -AnnotationAssertion( "PR:000001898") -AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") -AnnotationAssertion(rdfs:label "neprilysin") -AnnotationAssertion( ) -SubClassOf( ) - -# Class: (paired box protein PAX-5) - -AnnotationAssertion(Annotation( "PRO:WCB") "A protein that is a translation product of the human PAX5 gene or a 1:1 ortholog thereof.") -AnnotationAssertion( "B-cell-specific transcription factor") -AnnotationAssertion( "BSAP") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "PAX5") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( ) "Pax-5") -AnnotationAssertion( "PR:000001903") -AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") -AnnotationAssertion(rdfs:label "paired box protein PAX-5") -AnnotationAssertion( ) -SubClassOf( ) - -# Class: (scavenger receptor cysteine-rich type 1 protein M130) - -AnnotationAssertion(Annotation( "PRO:WCB") "A protein that is a translation product of the human CD163 gene or a 1:1 ortholog thereof.") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "CD163") -AnnotationAssertion( "hemoglobin scavenger receptor") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( ) "M130") -AnnotationAssertion( "PR:000001925") -AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") -AnnotationAssertion(rdfs:label "scavenger receptor cysteine-rich type 1 protein M130") -AnnotationAssertion( ) -SubClassOf( ) - -# Class: (signal transducer CD24) - -AnnotationAssertion(Annotation( "PRO:WCB") "A protein that is a translation product of the human CD24 gene or a 1:1 ortholog thereof.") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "CD24") -AnnotationAssertion( "HSA") -AnnotationAssertion( "M1/69-J11D heat stable antigen") -AnnotationAssertion( "R13-Ag") -AnnotationAssertion( "X62 heat stable antigen") -AnnotationAssertion( "ly-52") -AnnotationAssertion( "lymphocyte antigen 52") -AnnotationAssertion( "nectadrin") -AnnotationAssertion( "small cell lung carcinoma cluster 4 antigen") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( ) "CD24A") -AnnotationAssertion( "PR:000001932") -AnnotationAssertion(rdfs:comment "Category=gene. The mouse ortholog is Cd24a. Mouse protein Cd24b likely also orthologous. Currently it is not in UniProt. Requested by=CL.") -AnnotationAssertion(rdfs:label "signal transducer CD24") -AnnotationAssertion( ) -SubClassOf( ) - -# Class: (syndecan-1) - -AnnotationAssertion(Annotation( "PRO:WCB") "A protein that is a translation product of the human SDC1 gene or a 1:1 ortholog thereof.") -AnnotationAssertion( "PIRSF:PIRSF015854") -AnnotationAssertion( "CD138") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "SDC1") -AnnotationAssertion( "SYND1") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( ) "SDC") -AnnotationAssertion(Annotation( ) "Synd-1") -AnnotationAssertion( "PR:000001935") -AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") -AnnotationAssertion(rdfs:label "syndecan-1") -AnnotationAssertion( ) -SubClassOf( ) - -# Class: (tartrate-resistant acid phosphatase type 5) - -AnnotationAssertion(Annotation( "PRO:WCB") "A protein that is a translation product of the human ACP5 gene or a 1:1 ortholog thereof.") -AnnotationAssertion( "PIRSF:PIRSF000898") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "ACP5") -AnnotationAssertion( "TR-AP") -AnnotationAssertion( "TrATPase") -AnnotationAssertion( "tartrate-resistant acid ATPase") -AnnotationAssertion( "type 5 acid phosphatase") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( ) "T5ap") -AnnotationAssertion(Annotation( ) "Trap") -AnnotationAssertion( "PR:000001937") -AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") -AnnotationAssertion(rdfs:label "tartrate-resistant acid phosphatase type 5") -AnnotationAssertion( ) -SubClassOf( ) - -# Class: (thrombomodulin-like receptor) - -AnnotationAssertion(Annotation( "PRO:WCB") "A protein with core architecture consisting of a signal sequence, a Lectin C-type domain (Pfam:PF00059), 5 or 6 EGF-like domains (Pfam:PF00008, Pfam:PF09064, or Pfam:PF07645), a transmembrane region, and a small cytoplasmic region (36-51 amino acids).") -AnnotationAssertion( "PIRSF:PIRSF001775") -AnnotationAssertion( "protein") -AnnotationAssertion( "PR:000001938") -AnnotationAssertion(rdfs:comment "Category=family.") -AnnotationAssertion(rdfs:label "thrombomodulin-like receptor") -SubClassOf( ) - -# Class: (transcription factor PU.1) - -AnnotationAssertion(Annotation( "PRO:WCB") "A protein that is a translation product of the human SPI1 gene or a 1:1 ortholog thereof.") -AnnotationAssertion( "31 kDa-transforming protein") -AnnotationAssertion( "SFFV proviral integration 1 protein") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "SPI1") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( ) "Sfpi-1") -AnnotationAssertion(Annotation( ) "Sfpi1") -AnnotationAssertion( "PR:000001944") -AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") -AnnotationAssertion(rdfs:label "transcription factor PU.1") -AnnotationAssertion( ) -SubClassOf( ) - -# Class: (transferrin receptor protein 1) - -AnnotationAssertion(Annotation( "PRO:WCB") "A protein that is a translation product of the human TFRC gene or a 1:1 ortholog thereof.") -AnnotationAssertion(Annotation( "PRO:DNx") "p90") -AnnotationAssertion( "CD71") -AnnotationAssertion( "T9") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "TFRC") -AnnotationAssertion( "TfR") -AnnotationAssertion( "TfR1") -AnnotationAssertion( "protein") -AnnotationAssertion( "TR") -AnnotationAssertion(Annotation( ) "Trfr") -AnnotationAssertion( "PR:000001945") -AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") -AnnotationAssertion(rdfs:label "transferrin receptor protein 1") -AnnotationAssertion( ) -SubClassOf( ) - -# Class: (tumor necrosis factor receptor superfamily member 11A) - -AnnotationAssertion(Annotation( "PRO:WCB") "A protein that is a translation product of the human TNFRSF11A gene or a 1:1 ortholog thereof.") -AnnotationAssertion( "IUPHARobj:1881") -AnnotationAssertion( "PIRSF:PIRSF038806") -AnnotationAssertion( "CD265") -AnnotationAssertion( "ODFR") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "TNFRSF11A") -AnnotationAssertion( "osteoclast differentiation factor receptor") -AnnotationAssertion( "receptor activator of NF-KB") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( ) "RANK") -AnnotationAssertion( "PR:000001954") -AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") -AnnotationAssertion(rdfs:label "tumor necrosis factor receptor superfamily member 11A") -AnnotationAssertion( ) -SubClassOf( ) - -# Class: (CD27 molecule) - -AnnotationAssertion(Annotation( "PRO:WCB") "A protein that is a translation product of the human CD27 gene or a 1:1 ortholog thereof.") -AnnotationAssertion( "IUPHARobj:1876") -AnnotationAssertion( "PIRSF:PIRSF001966") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "CD27") -AnnotationAssertion( "CD27L receptor") -AnnotationAssertion( "T-cell activation antigen CD27") -AnnotationAssertion( "tumor necrosis factor receptor superfamily member 7") -AnnotationAssertion( "protein") -AnnotationAssertion( "T14") -AnnotationAssertion(Annotation( ) "TNFRSF7") -AnnotationAssertion( "PR:000001963") -AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") -AnnotationAssertion(rdfs:label "CD27 molecule") -SubClassOf( ) - -# Class: (urokinase plasminogen activator surface receptor) - -AnnotationAssertion(Annotation( "PRO:WCB") "A protein that is a translation product of the human PLAUR gene or a 1:1 ortholog thereof.") -AnnotationAssertion( "PIRSF:PIRSF002022") -AnnotationAssertion( "CD87") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "PLAUR") -AnnotationAssertion( "U-PAR") -AnnotationAssertion( "monocyte activation antigen Mo3") -AnnotationAssertion( "uPAR") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( ) "MO3") -AnnotationAssertion(Annotation( ) "UPAR") -AnnotationAssertion( "PR:000001969") -AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") -AnnotationAssertion(rdfs:label "urokinase plasminogen activator surface receptor") -AnnotationAssertion( ) -SubClassOf( ) - -# Class: (vascular endothelial growth factor receptor) - -AnnotationAssertion(Annotation( "PRO:WCB") "A protein with core architecture consisting of a signal sequence, followed by 7 Ig-like domains (Pfam:PF00047, Pfam:PF07679, or Pfam:PF07686), a transmembrane region, and a cytoplasmic Protein tyrosine kinase domain.") -AnnotationAssertion( "PIRSF:PIRSF038502") -AnnotationAssertion( "protein") -AnnotationAssertion( "PR:000001971") -AnnotationAssertion(rdfs:comment "Category=family.") -AnnotationAssertion(rdfs:label "vascular endothelial growth factor receptor") -SubClassOf( ) - -# Class: (receptor-type tyrosine-protein kinase FLT3) - -AnnotationAssertion(Annotation( "PRO:WCB") "A CSF-1/PDGF receptor-type tyrosine-protein kinase that is a translation product of the human FLT3 gene or a 1:1 ortholog thereof.") -AnnotationAssertion( "IUPHARobj:1807") -AnnotationAssertion( "PIRSF:PIRSF500949") -AnnotationAssertion( "FL cytokine receptor") -AnnotationAssertion( "FLK-2") -AnnotationAssertion( "FLT-3") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "FLT3") -AnnotationAssertion( "Fms-like tyrosine kinase 3") -AnnotationAssertion( "fetal liver kinase 2") -AnnotationAssertion( "stem cell tyrosine kinase 1") -AnnotationAssertion( "tyrosine-protein kinase FLT3") -AnnotationAssertion( "tyrosine-protein kinase receptor FLT3") -AnnotationAssertion( "tyrosine-protein kinase receptor flk-2") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( ) "CD135") -AnnotationAssertion(Annotation( ) "FLK2") -AnnotationAssertion( "STK-1") -AnnotationAssertion(Annotation( ) "STK1") -AnnotationAssertion( "PR:000002001") -AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") -AnnotationAssertion(rdfs:label "receptor-type tyrosine-protein kinase FLT3") -AnnotationAssertion( ) -SubClassOf( ) - -# Class: (complement component C1q receptor) - -AnnotationAssertion(Annotation( "PRO:WCB") "A thrombomodulin-like receptor that is a translation product of the human CD93 gene or a 1:1 ortholog thereof.") -AnnotationAssertion( "C1q/MBL/SPA receptor") -AnnotationAssertion( "C1qR") -AnnotationAssertion( "C1qR(p)") -AnnotationAssertion( "C1qRp") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "CD93") -AnnotationAssertion( "CDw93") -AnnotationAssertion( "Ly-68") -AnnotationAssertion( "cell surface antigen AA4") -AnnotationAssertion( "complement component 1 q subcomponent receptor 1") -AnnotationAssertion( "lymphocyte antigen 68") -AnnotationAssertion( "matrix-remodeling-associated protein 4") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( ) "Aa4") -AnnotationAssertion(Annotation( ) "C1QR1") -AnnotationAssertion(Annotation( ) "Ly68") -AnnotationAssertion(Annotation( ) "MXRA4") -AnnotationAssertion( "PR:000002037") -AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") -AnnotationAssertion(rdfs:label "complement component C1q receptor") -AnnotationAssertion( ) -SubClassOf( ) - -# Class: (glutamyl aminopeptidase) - -AnnotationAssertion(Annotation( "PRO:WCB") "A membrane alanyl aminopeptidase-like metallopeptidase that is a translation product of the human ENPEP gene or a 1:1 ortholog thereof.") -AnnotationAssertion( "IUPHARobj:1568") -AnnotationAssertion( "AP-A") -AnnotationAssertion( "BP-1/6C3 antigen") -AnnotationAssertion( "CD249") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "ENPEP") -AnnotationAssertion( "aminopeptidase A") -AnnotationAssertion( "differentiation antigen gp160") -AnnotationAssertion( "protein") -AnnotationAssertion( "EAP") -AnnotationAssertion( "PR:000002039") -AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") -AnnotationAssertion(rdfs:label "glutamyl aminopeptidase") -AnnotationAssertion( ) -SubClassOf( ) - -# Class: (macrophage colony-stimulating factor 1 receptor) - -AnnotationAssertion(Annotation( "PRO:WCB") "A CSF-1/PDGF receptor-type tyrosine-protein kinase that is a translation product of the human CSF1R gene or a 1:1 ortholog thereof.") -AnnotationAssertion( "IUPHARobj:1806") -AnnotationAssertion( "PIRSF:PIRSF500947") -AnnotationAssertion( "CD115") -AnnotationAssertion( "CSF-1 receptor") -AnnotationAssertion( "CSF-1-R") -AnnotationAssertion( "CSF-1R") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "CSF1R") -AnnotationAssertion( "M-CSF-R") -AnnotationAssertion( "proto-oncogene c-Fms") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( ) "Csfmr") -AnnotationAssertion(Annotation( ) "FMS") -AnnotationAssertion( "PR:000002062") -AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") -AnnotationAssertion(rdfs:label "macrophage colony-stimulating factor 1 receptor") -AnnotationAssertion( ) -SubClassOf( ) - -# Class: (mast/stem cell growth factor receptor) - -AnnotationAssertion(Annotation( "PRO:WCB") "A CSF-1/PDGF receptor-type tyrosine-protein kinase that is a translation product of the human KIT gene or a 1:1 ortholog thereof.") -AnnotationAssertion( "IUPHARobj:1805") -AnnotationAssertion( "PIRSF:PIRSF500951") -AnnotationAssertion( "CD117") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "KIT") -AnnotationAssertion( "proto-oncogene c-Kit") -AnnotationAssertion( "tyrosine-protein kinase Kit") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( ) "SCFR") -AnnotationAssertion(Annotation( ) "Sl") -AnnotationAssertion( "PR:000002065") -AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") -AnnotationAssertion(rdfs:label "mast/stem cell growth factor receptor") -SubClassOf( ) - -# Class: (vascular endothelial growth factor receptor 2) - -AnnotationAssertion(Annotation( "PRO:WCB") "A vascular endothelial growth factor receptor that is a translation product of the human KDR gene or a 1:1 ortholog thereof.") -AnnotationAssertion( "IUPHARobj:1813") -AnnotationAssertion( "CD309") -AnnotationAssertion( "FLK-1") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "KDR") -AnnotationAssertion( "VEGFR-2") -AnnotationAssertion( "fetal liver kinase 1") -AnnotationAssertion( "kinase NYK") -AnnotationAssertion( "kinase insert domain receptor") -AnnotationAssertion( "protein-tyrosine kinase receptor flk-1") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( ) "FLK1") -AnnotationAssertion(Annotation( ) "VEGFR2") -AnnotationAssertion( "PR:000002112") -AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") -AnnotationAssertion(rdfs:label "vascular endothelial growth factor receptor 2") -AnnotationAssertion( ) -SubClassOf( ) - -# Class: (Ly-6-like protein) - -AnnotationAssertion(Annotation( "PRO:CNA") "A protein that is the translation product of any of the LY6 genes (LY6A-LY6I).") -AnnotationAssertion( "PIRSF:PIRSF002021") -AnnotationAssertion( "protein") -AnnotationAssertion( "PR:000002976") -AnnotationAssertion(rdfs:comment "Category=family.") -AnnotationAssertion(rdfs:label "Ly-6-like protein") -SubClassOf( ) - -# Class: (killer cell lectin-like receptor subfamily B member 1C) - -AnnotationAssertion(Annotation( "PRO:CNA") "A KLRB1-like protein that is a translation product of the mouse Klrb1c gene or a 1:1 ortholog thereof.") -AnnotationAssertion( "CD161 antigen-like family member C") -AnnotationAssertion( "CD161c") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "Klrb1c") -AnnotationAssertion( "NK1.1") -AnnotationAssertion( "NKR-P1 40") -AnnotationAssertion( "NKR-P1.9") -AnnotationAssertion( "NKR-P1C") -AnnotationAssertion( "ly-55c") -AnnotationAssertion( "lymphocyte antigen 55c") -AnnotationAssertion( "natural killer cell surface protein P1-40") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( ) "Ly55c") -AnnotationAssertion(Annotation( ) "Nkrp1c") -AnnotationAssertion( "PR:000002977") -AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") -AnnotationAssertion(rdfs:label "killer cell lectin-like receptor subfamily B member 1C") -SubClassOf( ) - -# Class: (lymphocyte antigen 6G) - -AnnotationAssertion(Annotation( "PRO:CNA") "An Ly-6-like protein that is a translation product of the mouse Ly6g gene or a 1:1 ortholog thereof.") -AnnotationAssertion( "Ly-6G") -AnnotationAssertion( "Ly-6G.1") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "Ly6g") -AnnotationAssertion( "protein") -AnnotationAssertion( "PR:000002978") -AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") -AnnotationAssertion(rdfs:label "lymphocyte antigen 6G") -SubClassOf( ) - -# Class: (lymphocyte antigen 6A-2/6E-1) - -AnnotationAssertion(Annotation( "PRO:CNA") "An Ly-6-like protein that is a translation product of the mouse Ly6a gene or a 1:1 ortholog thereof.") -AnnotationAssertion( "Ly-6A.2/Ly-6E.1") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "Ly6a") -AnnotationAssertion( "T-cell-activating protein") -AnnotationAssertion( "stem cell antigen 1") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( ) "Ly6") -AnnotationAssertion( "SCA-1") -AnnotationAssertion( "TAP") -AnnotationAssertion( "PR:000002979") -AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") -AnnotationAssertion(rdfs:label "lymphocyte antigen 6A-2/6E-1") -SubClassOf( ) - -# Class: (lymphocyte antigen 6C2) - -AnnotationAssertion(Annotation( "PRO:CNA") "An Ly-6-like protein that is a translation product of the mouse Ly6c2 gene or a 1:1 ortholog thereof.") -AnnotationAssertion( "Ly-6C2") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "Ly6c2") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( ) "Ly6c") -AnnotationAssertion( "PR:000002980") -AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") -AnnotationAssertion(rdfs:label "lymphocyte antigen 6C2") -SubClassOf( ) - -# Class: (lymphocyte antigen 76 (mouse)) - -AnnotationAssertion(Annotation( "PMID:10848813") Annotation( "PRO:DAN") "A protein that is a translation product of the Ly76 gene in mouse.") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mLy76") -AnnotationAssertion( "ter-119") -AnnotationAssertion( "ter119") -AnnotationAssertion( "protein") -AnnotationAssertion( "PR:000002981") -AnnotationAssertion(rdfs:comment "Category=organism-gene. Requested by=CL.") -AnnotationAssertion(rdfs:label "lymphocyte antigen 76 (mouse)") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (V(D)J recombination-activating protein 1) - -AnnotationAssertion(Annotation( "PRO:CNA") "A protein that is a translation product of the human RAG1 gene or a 1:1 ortholog thereof.") -AnnotationAssertion( "RAG-1") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "RAG1") -AnnotationAssertion( "RING finger protein 74") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( ) "RNF74") -AnnotationAssertion( "PR:000003457") -AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") -AnnotationAssertion(rdfs:label "V(D)J recombination-activating protein 1") -AnnotationAssertion( ) -SubClassOf( ) - -# Class: (V(D)J recombination-activating protein 2) - -AnnotationAssertion(Annotation( "PRO:CNA") "A protein that is a translation product of the human RAG2 gene or a 1:1 ortholog thereof.") -AnnotationAssertion( "RAG-2") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "RAG2") -AnnotationAssertion( "protein") -AnnotationAssertion( "PR:000003460") -AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") -AnnotationAssertion(rdfs:label "V(D)J recombination-activating protein 2") -AnnotationAssertion( ) -SubClassOf( ) - -# Class: (lactosylceramide 4-alpha-galactosyltransferase) - -AnnotationAssertion(Annotation( "PRO:DNx") "A protein that is a translation product of the human A4GALT gene or a 1:1 ortholog thereof.") -AnnotationAssertion(Annotation( "PRO:DNx") "alpha-1,4-N-acetylglucosaminyltransferase") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "A4GALT") -AnnotationAssertion( "CD77 synthase") -AnnotationAssertion( "Gb3 synthase") -AnnotationAssertion( "P1/Pk synthase") -AnnotationAssertion( "UDP-galactose:beta-D-galactosyl-beta1-R 4-alpha-D-galactosyltransferase") -AnnotationAssertion( "alpha-1,4-galactosyltransferase") -AnnotationAssertion( "alpha4Gal-T1") -AnnotationAssertion( "globotriaosylceramide synthase") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( ) "A14GALT") -AnnotationAssertion(Annotation( ) "A4GALT1") -AnnotationAssertion( "PR:000003516") -AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") -AnnotationAssertion(rdfs:label "lactosylceramide 4-alpha-galactosyltransferase") -AnnotationAssertion( ) -SubClassOf( ) - -# Class: (CCAAT/enhancer-binding protein alpha) - -AnnotationAssertion(Annotation( "PRO:DNx") "A protein that is a translation product of the human CEBPA gene or a 1:1 ortholog thereof.") -AnnotationAssertion( "C/EBP alpha") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "CEBPA") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( ) "CEBP") -AnnotationAssertion( "PR:000005307") -AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") -AnnotationAssertion(rdfs:label "CCAAT/enhancer-binding protein alpha") -AnnotationAssertion( ) -SubClassOf( ) - -# Class: (DNA nucleotidylexotransferase) - -AnnotationAssertion(Annotation( "PRO:DNx") "A protein that is a translation product of the human DNTT gene or a 1:1 ortholog thereof.") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "DNTT") -AnnotationAssertion( "terminal addition enzyme") -AnnotationAssertion( "terminal deoxynucleotidyltransferase") -AnnotationAssertion( "terminal transferase") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( ) "TDT") -AnnotationAssertion( "PR:000006611") -AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") -AnnotationAssertion(rdfs:label "DNA nucleotidylexotransferase") -AnnotationAssertion( ) -SubClassOf( ) - # Class: (fibroblast growth factor 8) AnnotationAssertion(Annotation( "PRO:DNx") "A protein that is a translation product of the human FGF8 gene or a 1:1 ortholog thereof.") @@ -146779,22 +35176,6 @@ AnnotationAssertion(rdfs:label "fi AnnotationAssertion( ) SubClassOf( ) -# Class: (protein c-Fos) - -AnnotationAssertion(Annotation( "PRO:DNx") "A protein that is a translation product of the human FOS gene or a 1:1 ortholog thereof.") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "FOS") -AnnotationAssertion( "G0/G1 switch regulatory protein 7") -AnnotationAssertion( "cellular oncogene fos") -AnnotationAssertion( "proto-oncogene protein c-fos") -AnnotationAssertion( "transcription factor AP-1 subunit c-Fos") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( ) "G0S7") -AnnotationAssertion( "PR:000007597") -AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") -AnnotationAssertion(rdfs:label "protein c-Fos") -AnnotationAssertion( ) -SubClassOf( ) - # Class: (forkhead box protein N1) AnnotationAssertion(Annotation( "PRO:DNx") "A protein that is a translation product of the human FOXN1 gene or a 1:1 ortholog thereof.") @@ -146815,77 +35196,6 @@ AnnotationAssertion(rdfs:label "fo AnnotationAssertion( ) SubClassOf( ) -# Class: (erythroid transcription factor) - -AnnotationAssertion(Annotation( "PRO:DNx") "A protein that is a translation product of the human GATA1 gene or a 1:1 ortholog thereof.") -AnnotationAssertion( "Eryf1") -AnnotationAssertion( "GATA-1") -AnnotationAssertion( "GATA-binding factor 1") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "GATA1") -AnnotationAssertion( "NF-E1 DNA-binding protein") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( ) "ERYF1") -AnnotationAssertion( "GF-1") -AnnotationAssertion(Annotation( ) "GF1") -AnnotationAssertion( "PR:000007857") -AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") -AnnotationAssertion(rdfs:label "erythroid transcription factor") -AnnotationAssertion( ) -SubClassOf( ) - -# Class: (endothelial transcription factor GATA-2) - -AnnotationAssertion(Annotation( "PRO:DNx") "A protein that is a translation product of the human GATA2 gene or a 1:1 ortholog thereof.") -AnnotationAssertion( "GATA-binding protein 2") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "GATA2") -AnnotationAssertion( "protein") -AnnotationAssertion( "PR:000007858") -AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") -AnnotationAssertion(rdfs:label "endothelial transcription factor GATA-2") -AnnotationAssertion( ) -SubClassOf( ) - -# Class: (glial fibrillary acidic protein) - -AnnotationAssertion(Annotation( "PRO:DNx") "A protein that is a translation product of the human GFAP gene or a 1:1 ortholog thereof.") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "GFAP") -AnnotationAssertion( "protein") -AnnotationAssertion( "PR:000007939") -AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") -AnnotationAssertion(rdfs:label "glial fibrillary acidic protein") -AnnotationAssertion( ) -SubClassOf( ) - -# Class: (insulin gene translation product) - -AnnotationAssertion(Annotation( "PRO:DNx") "An insulin family protein that is a translation product of the human INS gene or a 1:1 ortholog thereof.") -AnnotationAssertion(Annotation( "PRO:DAN") "insulin") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "INS") -AnnotationAssertion( "protein") -AnnotationAssertion( "PR:000009054") -AnnotationAssertion(rdfs:comment "Category=gene.") -AnnotationAssertion(rdfs:label "insulin gene translation product") -AnnotationAssertion( ) -SubClassOf( ) - -# Class: (integrin alpha-IIb) - -AnnotationAssertion(Annotation( "PRO:DNx") "An integrin alpha lacking A domain that is a translation product of the human ITGA2B gene or a 1:1 ortholog thereof.") -AnnotationAssertion( "IUPHARobj:2441") -AnnotationAssertion( "CD41") -AnnotationAssertion( "GPIIb") -AnnotationAssertion( "GPalpha IIb") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "ITGA2B") -AnnotationAssertion( "platelet membrane glycoprotein IIb") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( ) "GP2B") -AnnotationAssertion(Annotation( ) "ITGAB") -AnnotationAssertion( "PR:000009127") -AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") -AnnotationAssertion(rdfs:label "integrin alpha-IIb") -AnnotationAssertion( ) -SubClassOf( ) - # Class: (lactotransferrin) AnnotationAssertion(Annotation( "PRO:DNx") "A protein that is a translation product of the human LTF gene or a 1:1 ortholog thereof.") @@ -146915,48 +35225,6 @@ AnnotationAssertion(rdfs:label "my AnnotationAssertion( ) SubClassOf( ) -# Class: (nuclear factor NF-kappa-B p100 subunit) - -AnnotationAssertion(Annotation( "PRO:DNx") "A transcription factor NF-kappa-B subunit that is a translation product of the human NFKB2 gene or a 1:1 ortholog thereof.") -AnnotationAssertion( "DNA-binding factor KBF2") -AnnotationAssertion( "H2TF1") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "NFKB2") -AnnotationAssertion( "lymphocyte translocation chromosome 10 protein") -AnnotationAssertion( "lyt10") -AnnotationAssertion( "nuclear factor of kappa light polypeptide gene enhancer in B-cells 2") -AnnotationAssertion( "oncogene Lyt-10") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( ) "LYT10") -AnnotationAssertion( "PR:000011178") -AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") -AnnotationAssertion(rdfs:label "nuclear factor NF-kappa-B p100 subunit") -AnnotationAssertion( ) -SubClassOf( ) - -# Class: (prolactin) - -AnnotationAssertion(Annotation( "PRO:DNx") "A somatotropin hormone family member that is a translation product of the human PRL gene or a 1:1 ortholog thereof.") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "PRL") -AnnotationAssertion( "protein") -AnnotationAssertion( "PR:000013246") -AnnotationAssertion(rdfs:comment "Category=gene.") -AnnotationAssertion(rdfs:label "prolactin") -AnnotationAssertion( ) -SubClassOf( ) - -# Class: (renin) - -AnnotationAssertion(Annotation( "PRO:DAN") "An angiotensinogenase that is a translation product of the human REN gene or a 1:1 ortholog thereof.") -AnnotationAssertion( "IUPHARobj:2413") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "REN") -AnnotationAssertion( "protein") -AnnotationAssertion( "angiotensinogenase") -AnnotationAssertion( "PR:000013883") -AnnotationAssertion(rdfs:comment "Category=gene.") -AnnotationAssertion(rdfs:label "renin") -AnnotationAssertion( ) -SubClassOf( ) - # Class: (sonic hedgehog protein) AnnotationAssertion(Annotation( "PRO:DNx") "A protein that is a translation product of the human SHH gene or a 1:1 ortholog thereof.") @@ -147000,25 +35268,6 @@ AnnotationAssertion(rdfs:label "SC AnnotationAssertion( ) SubClassOf( ) -# Class: (T-cell acute lymphocytic leukemia protein 1) - -AnnotationAssertion(Annotation( "PRO:DNx") "A protein that is a translation product of the human TAL1 gene or a 1:1 ortholog thereof.") -AnnotationAssertion( "T-cell leukemia/lymphoma protein 5") -AnnotationAssertion( "TAL-1") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "TAL1") -AnnotationAssertion( "bHLHa17") -AnnotationAssertion( "class A basic helix-loop-helix protein 17") -AnnotationAssertion( "stem cell protein") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( ) "BHLHA17") -AnnotationAssertion(Annotation( ) "SCL") -AnnotationAssertion(Annotation( ) "TCL5") -AnnotationAssertion( "PR:000016043") -AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") -AnnotationAssertion(rdfs:label "T-cell acute lymphocytic leukemia protein 1") -AnnotationAssertion( ) -SubClassOf( ) - # Class: (thyroglobulin) AnnotationAssertion(Annotation( "PRO:DNx") "A protein that is a translation product of the human TG gene or a 1:1 ortholog thereof.") @@ -147053,186 +35302,9 @@ AnnotationAssertion(Annotation( "protein") AnnotationAssertion( "PR:000018264") AnnotationAssertion(rdfs:label "proteolytic cleavage product") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (CD48 molecule proteolytic cleavage product) - -AnnotationAssertion(Annotation( "PRO:DNx") "A CD48 molecule that has been processed by proteolytic cleavage.") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "CD48/ClvPrd") -AnnotationAssertion( "protein") -AnnotationAssertion( "PR:000018381") -AnnotationAssertion(rdfs:comment "Category=modification.") -AnnotationAssertion(rdfs:label "CD48 molecule proteolytic cleavage product") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (carcinoembryonic antigen-related cell adhesion molecule 8 proteolytic cleavage product) - -AnnotationAssertion(Annotation( "PRO:DNx") "A carcinoembryonic antigen-related cell adhesion molecule 8 that has been processed by proteolytic cleavage.") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "CEACAM8/ClvPrd") -AnnotationAssertion( "protein") -AnnotationAssertion( "PR:000018406") -AnnotationAssertion(rdfs:comment "Category=modification.") -AnnotationAssertion(rdfs:label "carcinoembryonic antigen-related cell adhesion molecule 8 proteolytic cleavage product") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (Thy-1 membrane glycoprotein proteolytic cleavage product) - -AnnotationAssertion(Annotation( "PRO:DNx") "A Thy-1 membrane glycoprotein that has been processed by proteolytic cleavage.") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "THY1/ClvPrd") -AnnotationAssertion( "protein") -AnnotationAssertion( "PR:000018546") -AnnotationAssertion(rdfs:comment "Category=modification.") -AnnotationAssertion(rdfs:label "Thy-1 membrane glycoprotein proteolytic cleavage product") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cathepsin K proteolytic cleavage product) - -AnnotationAssertion(Annotation( "PRO:DNx") "A cathepsin K that has been processed by proteolytic cleavage.") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "CTSK/ClvPrd") -AnnotationAssertion( "protein") -AnnotationAssertion( "PR:000018547") -AnnotationAssertion(rdfs:comment "Category=modification.") -AnnotationAssertion(rdfs:label "cathepsin K proteolytic cleavage product") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (low affinity immunoglobulin epsilon Fc receptor proteolytic cleavage product) - -AnnotationAssertion(Annotation( "PRO:DNx") "A low affinity immunoglobulin epsilon Fc receptor that has been processed by proteolytic cleavage.") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "FCER2/ClvPrd") -AnnotationAssertion( "protein") -AnnotationAssertion( "PR:000018568") -AnnotationAssertion(rdfs:comment "Category=modification.") -AnnotationAssertion(rdfs:label "low affinity immunoglobulin epsilon Fc receptor proteolytic cleavage product") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (scavenger receptor cysteine-rich type 1 protein M130 proteolytic cleavage product) - -AnnotationAssertion(Annotation( "PRO:DNx") "A scavenger receptor cysteine-rich type 1 protein M130 that has been processed by proteolytic cleavage.") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "CD163/ClvPrd") -AnnotationAssertion( "protein") -AnnotationAssertion( "PR:000018594") -AnnotationAssertion(rdfs:comment "Category=modification.") -AnnotationAssertion(rdfs:label "scavenger receptor cysteine-rich type 1 protein M130 proteolytic cleavage product") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (transferrin receptor protein 1 proteolytic cleavage product) - -AnnotationAssertion(Annotation( "PRO:DNx") "A transferrin receptor protein 1 that has been processed by proteolytic cleavage.") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "TFRC/ClvPrd") -AnnotationAssertion( "protein") -AnnotationAssertion( "PR:000018603") -AnnotationAssertion(rdfs:comment "Category=modification.") -AnnotationAssertion(rdfs:label "transferrin receptor protein 1 proteolytic cleavage product") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (integrin alpha-IIb proteolytic cleavage product) - -AnnotationAssertion(Annotation( "PRO:DNx") "An integrin alpha-IIb that has been processed by proteolytic cleavage.") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "ITGA2B/ClvPrd") -AnnotationAssertion( "protein") -AnnotationAssertion( "PR:000020329") -AnnotationAssertion(rdfs:comment "Category=modification.") -AnnotationAssertion(rdfs:label "integrin alpha-IIb proteolytic cleavage product") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (lactotransferrin proteolytic cleavage product) - -AnnotationAssertion(Annotation( "PRO:DNx") "A lactotransferrin that has been processed by proteolytic cleavage.") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "LTF/ClvPrd") -AnnotationAssertion( "protein") -AnnotationAssertion( "PR:000020497") -AnnotationAssertion(rdfs:comment "Category=modification.") -AnnotationAssertion(rdfs:label "lactotransferrin proteolytic cleavage product") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (nuclear factor NF-kappa-B p100 subunit proteolytic cleavage product) - -AnnotationAssertion(Annotation( "PRO:DNx") "A nuclear factor NF-kappa-B p100 subunit that has been processed by proteolytic cleavage.") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "NFKB2/ClvPrd") -AnnotationAssertion( "protein") -AnnotationAssertion( "PR:000020735") -AnnotationAssertion(rdfs:comment "Category=modification.") -AnnotationAssertion(rdfs:label "nuclear factor NF-kappa-B p100 subunit proteolytic cleavage product") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (sonic hedgehog protein proteolytic cleavage product) - -AnnotationAssertion(Annotation( "PRO:DNx") "A sonic hedgehog protein that has been processed by proteolytic cleavage.") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "SHH/ClvPrd") -AnnotationAssertion( "protein") -AnnotationAssertion( "PR:000021468") -AnnotationAssertion(rdfs:comment "Category=modification.") -AnnotationAssertion(rdfs:label "sonic hedgehog protein proteolytic cleavage product") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (CD2 molecule proteolytic cleavage product) - -AnnotationAssertion(Annotation( "PRO:DNx") "A CD2 molecule that has been processed by proteolytic cleavage.") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "CD2/ClvPrd") -AnnotationAssertion( "protein") -AnnotationAssertion( "PR:000025455") -AnnotationAssertion(rdfs:comment "Category=modification.") -AnnotationAssertion(rdfs:label "CD2 molecule proteolytic cleavage product") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (integrin alpha) - -AnnotationAssertion(Annotation( "PMID:19693543") "A protein that is composed of a long N-terminal extracellular domain, a transmembrane domain and a short cytoplasmic C-terminal domain. The N-terminal domain contains beta-propeller repeats (interrupted by an A domain in a subset of integrins alpha), while the C-terminal domain contains a GFFxR motif.") -AnnotationAssertion( "protein") -AnnotationAssertion( "PR:000025796") -AnnotationAssertion(rdfs:comment "Category=family. Integrins are heterodimeric complexes of an alpha and a beta subunit. They are a structurally elaborate family of adhesion molecules that transmit signals bidirectionally across the plasma membrane by undergoing large-scale structural rearrangements. By regulating cell-cell and cell-matrix contacts, integrins participate in a wide-range of biological interactions including development, tissue repair, angiogenesis, inflammation and hemostasis. [PMID:10402956, PMID:11988479, PMID:9676575].") -AnnotationAssertion(rdfs:label "integrin alpha") -SubClassOf( ) - -# Class: (integrin alpha lacking A domain) - -AnnotationAssertion(Annotation( "PRO:DAN") "An integrin alpha that lacks an A domain. This type of integrin is often cleaved into heavy and light chains.") -AnnotationAssertion( "PIRSF:PIRSF005666") -AnnotationAssertion(Annotation( "PRO:DAN") Annotation( ) "fam:ITGAsansA") -AnnotationAssertion( "protein") -AnnotationAssertion( "PR:000025797") -AnnotationAssertion(rdfs:comment "Category=family.") -AnnotationAssertion(rdfs:label "integrin alpha lacking A domain") -SubClassOf( ) - # Class: (CALCA gene translation product) AnnotationAssertion(Annotation( "MGI:2151253") Annotation( "PRO:CNA") "A protein that is a translation product of the human CALCA gene or a 1:1 ortholog thereof.") @@ -147245,19 +35317,6 @@ AnnotationAssertion(rdfs:label "CA AnnotationAssertion( ) SubClassOf( ) -# Class: (CALCA gene translation product (mouse)) - -AnnotationAssertion(Annotation( "MGI:2151253") Annotation( "PRO:HJD") "A CALCA gene translation product that is encoded in the genome of mouse.") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mCALCA") -AnnotationAssertion( "protein") -AnnotationAssertion( "PR:000027223") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "CALCA gene translation product (mouse)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (casein derived peptide) AnnotationAssertion(Annotation( "PRO:DAN") "A proteolytic cleavage product that is derived from any of the casein milk proteins.") @@ -147268,149 +35327,6 @@ AnnotationAssertion(rdfs:comment " AnnotationAssertion(rdfs:label "casein derived peptide") SubClassOf( ) -# Class: (Mus musculus protein) - -AnnotationAssertion(Annotation( "PRO:DAN") "A protein that is encoded in the genome of Mus musculus.") -AnnotationAssertion(Annotation( "PRO:DAN") Annotation( ) "mouse protein") -AnnotationAssertion( "protein") -AnnotationAssertion( "PR:000029032") -AnnotationAssertion(rdfs:label "Mus musculus protein") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (Gallus gallus protein) - -AnnotationAssertion(Annotation( "PRO:DAN") "A protein that is encoded in the genome of Gallus gallus.") -AnnotationAssertion(Annotation( "PRO:DAN") Annotation( ) "chicken protein") -AnnotationAssertion( "protein") -AnnotationAssertion( "PR:000029063") -AnnotationAssertion(rdfs:label "Gallus gallus protein") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (Homo sapiens protein) - -AnnotationAssertion(Annotation( "PRO:DAN") "A protein that is encoded in the genome of Homo sapiens.") -AnnotationAssertion(Annotation( "PRO:DAN") Annotation( ) "human protein") -AnnotationAssertion( "protein") -AnnotationAssertion( "PR:000029067") -AnnotationAssertion(rdfs:label "Homo sapiens protein") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (somatotropin hormone family member) - -AnnotationAssertion(Annotation( "PRO:DAN") "A protein that is a standalone version of the Hormone_1 domain (Pfam:PF00103). In the immature form, the domain is preceded by a signal peptide.") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "fam:GH1") -AnnotationAssertion( "protein") -AnnotationAssertion( "PR:000029968") -AnnotationAssertion(rdfs:comment "Category=family.") -AnnotationAssertion(rdfs:label "somatotropin hormone family member") -SubClassOf( ) - -# Class: (CALCA gene translation product (human)) - -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( "UniProtKB:P06881") "A CALCA gene translation product that is encoded in the genome of human.") -AnnotationAssertion(Annotation( "UniProtKB:P06881") "CALC1 (human)") -AnnotationAssertion(Annotation( "UniProtKB:P06881") "CGRP-I (human)") -AnnotationAssertion(Annotation( "UniProtKB:P06881") "alpha-type CGRP (human)") -AnnotationAssertion(Annotation( "UniProtKB:P06881") "calcitonin gene-related peptide I (human)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hCALCA") -AnnotationAssertion( "protein") -AnnotationAssertion( "PR:000030026") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "CALCA gene translation product (human)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (G-protein coupled receptor) - -AnnotationAssertion(Annotation( "IUPHARfam:694") Annotation( "PRO:DAN") Annotation( "Wikipedia:GPCR") "A protein that has G protein-coupled receptor (GPCR) activity. Each GPCR consists of a single polypeptide with an extracellular N-terminus, an intracellular C-terminus and seven hydrophobic transmembrane domains (TM1-TM7) linked by three extracellular loops (ECL1-ECL3) and three intracellular loops (ICL1-ICL3). GPCRs function as part of a heterotrimeric complex to transmit an extracellular signal across the membrane by activating an associated G-protein via the exchange of GDP for GTP on the alpha subunit.") -AnnotationAssertion(Annotation( "IUPHARfam:694") "7TM receptor") -AnnotationAssertion(Annotation( "IUPHARfam:694") "seven-transmembrane receptor") -AnnotationAssertion( "IUPHARfam:694") -AnnotationAssertion(Annotation( "PRO:DAN") Annotation( ) "fam:GPCR") -AnnotationAssertion( "protein") -AnnotationAssertion( "PR:000030035") -AnnotationAssertion(rdfs:comment "Category=family. Classification based on GRAFS system. [PMID:12761335]") -AnnotationAssertion(rdfs:label "G-protein coupled receptor") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (eukaryotic protein) - -AnnotationAssertion(Annotation( "PRO:DAN") "A protein that is encoded in the genome of some Eukaryota.") -AnnotationAssertion(Annotation( "PRO:DAN") "Eukaryota protein") -AnnotationAssertion( "protein") -AnnotationAssertion( "PR:000036194") -AnnotationAssertion(rdfs:label "eukaryotic protein") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (CALCA gene translation product (chicken)) - -AnnotationAssertion(Annotation( "PRO:DAN") "A CALCA gene translation product that is encoded in the genome of chicken.") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "chick-CALCA") -AnnotationAssertion( "protein") -AnnotationAssertion( "PR:000036870") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "CALCA gene translation product (chicken)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cathepsin-like protease) - -AnnotationAssertion(Annotation( "PRO:DAN") "A protein that is a translation product of some metazoan gene that encodes a signal peptide followed by a single Cathepsin propeptide inhibitor domain (Pfam:PF08246) followed by a single Papain family cysteine protease (Pfam:PF00112) domain at the C terminus.") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "fam:CTS") -AnnotationAssertion(Annotation( "PRO:DAN") "cathepsin") -AnnotationAssertion( "protein") -AnnotationAssertion( "PR:000040662") -AnnotationAssertion(rdfs:comment "Category=family.") -AnnotationAssertion(rdfs:label "cathepsin-like protease") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (insulin family protein) - -AnnotationAssertion(Annotation( "PRO:DAN") "A protein that is a translation product of a gene that encodes a standalone Insulin (Pfam:PF00049) domain preceded by a signal peptide.") -AnnotationAssertion(Annotation( "PRO:DAN") Annotation( ) "fam:INS") -AnnotationAssertion( "protein") -AnnotationAssertion( "PR:000045358") -AnnotationAssertion(rdfs:comment "Category=family.") -AnnotationAssertion(rdfs:label "insulin family protein") -SubClassOf( ) - -# Class: (angiotensinogenase) - -AnnotationAssertion(Annotation( "PRO:DAN") "A protein that is a translation product of the mouse Ren1 or Ren2 genes, 1:1 orthologs thereof, or a semi-ortholog thereof.") -AnnotationAssertion(Annotation( "PRO:DAN") Annotation( ) "fam:angiotensinogenase") -AnnotationAssertion( "protein") -AnnotationAssertion( "PR:000050025") -AnnotationAssertion(rdfs:comment "Category=family.") -AnnotationAssertion(rdfs:label "angiotensinogenase") -SubClassOf( ) - -# Class: (receptor-type tyrosine-protein phosphatase C isoform CD45R) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "PRO:ADD") Annotation( "PRO:DAN") "A receptor-type tyrosine-protein phosphatase C that is a translation product of a transcript that minimally includes the region encoded by the variable exon 4(A).") -AnnotationAssertion( "CD45R") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "PTPRC/iso:CD45R") -AnnotationAssertion( "protein") -AnnotationAssertion( "PR:000050216") -AnnotationAssertion(rdfs:comment "Category=seqgroup. Requested by=CL.") -AnnotationAssertion(rdfs:label "receptor-type tyrosine-protein phosphatase C isoform CD45R") -SubClassOf( ) - # Class: (protein-containing material entity) AnnotationAssertion(Annotation( "PRO:DAN") "A material entity that minimally consists of a protein.") @@ -147422,3605 +35338,9 @@ AnnotationAssertion( "PR:000050567") AnnotationAssertion(rdfs:comment "Note: This includes single proteins and derivatives thereof (PR:000000001), protein-containing complexes (GO:0032991), and protein aggregates (PR:000050566).") AnnotationAssertion(rdfs:label "protein-containing material entity") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (interleukin-7 receptor alpha chain (chicken)) - -AnnotationAssertion(Annotation( "OMA:A1EA95") Annotation( "PRO:DNx") "An interleukin-7 receptor subunit alpha that is encoded in the genome of chicken.") -AnnotationAssertion( "UniProtKB:A1EA95") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "chick-IL7R") -AnnotationAssertion( "protein") -AnnotationAssertion( "PR:A1EA95") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "interleukin-7 receptor alpha chain (chicken)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (SCO-spondin (human)) - -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( "UniProtKB:A2VEC9") "A SCO-spondin that is encoded in the genome of human.") -AnnotationAssertion( "UniProtKB:A2VEC9") -AnnotationAssertion(Annotation( "UniProtKB:A2VEC9") "SCO-spondin pseudogene (human)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hSSPO") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:A2VEC9") Annotation( ) "KIAA2036") -AnnotationAssertion(Annotation( "UniProtKB:A2VEC9") Annotation( ) "SSPO") -AnnotationAssertion(Annotation( "UniProtKB:A2VEC9") Annotation( ) "SSPOP") -AnnotationAssertion( "PR:A2VEC9") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "SCO-spondin (human)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (CD14 molecule (chicken)) - -AnnotationAssertion(Annotation( "PRO:CNA") "A CD14 molecule that is encoded in the genome of chicken.") -AnnotationAssertion( "UniProtKB:B0BL87") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "chick-CD14") -AnnotationAssertion( "protein") -AnnotationAssertion( "PR:B0BL87") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "CD14 molecule (chicken)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (interleukin-5 receptor subunit alpha isoform 2 (chicken)) - -AnnotationAssertion(Annotation( "PRO:WCB") "An interleukin-5 receptor subunit alpha that is encoded in the genome of chicken.") -AnnotationAssertion( "UniProtKB:E1C261") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "chick-IL5RA") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:E1C261") Annotation( ) "IL-5R alpha") -AnnotationAssertion( "PR:E1C261") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "interleukin-5 receptor subunit alpha isoform 2 (chicken)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (uncharacterized protein, PROM1 translation product (chicken)) - -AnnotationAssertion(Annotation( "OMA:E1C9E2") Annotation( "PRO:CNA") "A prominin-1 that is encoded in the genome of chicken.") -AnnotationAssertion( "UniProtKB:E1C9E2") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "chick-PROM1") -AnnotationAssertion( "protein") -AnnotationAssertion( "PR:E1C9E2") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "uncharacterized protein, PROM1 translation product (chicken)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (uncharacterized protein, CD8A translation product (chicken)) - -AnnotationAssertion(Annotation( "PRO:CNA") "A T-cell surface glycoprotein CD8 alpha chain that is encoded in the genome of chicken.") -AnnotationAssertion( "UniProtKB:F1NXT4") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "chick-CD8A") -AnnotationAssertion( "protein") -AnnotationAssertion( "PR:F1NXT4") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "uncharacterized protein, CD8A translation product (chicken)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (thyroglobulin (mouse)) - -AnnotationAssertion(Annotation( "OMA:O08710") Annotation( "PRO:DNx") "A thyroglobulin that is encoded in the genome of mouse.") -AnnotationAssertion( "UniProtKB:O08710") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mTG") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:O08710") Annotation( ) "Tg") -AnnotationAssertion(Annotation( "UniProtKB:O08710") Annotation( ) "Tgn") -AnnotationAssertion( "PR:O08710") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "thyroglobulin (mouse)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (endothelial transcription factor GATA-2 (mouse)) - -AnnotationAssertion(Annotation( "OMA:O09100") Annotation( "PRO:DNx") "An endothelial transcription factor GATA-2 that is encoded in the genome of mouse.") -AnnotationAssertion( "UniProtKB:O09100") -AnnotationAssertion(Annotation( "UniProtKB:O09100") "GATA-binding protein 2 (mouse)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mGATA2") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:O09100") Annotation( ) "Gata2") -AnnotationAssertion( "PR:O09100") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "endothelial transcription factor GATA-2 (mouse)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (forkhead box protein N1 (human)) - -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( "UniProtKB:O15353") "A forkhead box protein N1 that is encoded in the genome of human.") -AnnotationAssertion( "UniProtKB:O15353") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hFOXN1") -AnnotationAssertion(Annotation( "UniProtKB:O15353") "winged-helix transcription factor nude (human)") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:O15353") Annotation( ) "FOXN1") -AnnotationAssertion(Annotation( "UniProtKB:O15353") Annotation( ) "RONU") -AnnotationAssertion(Annotation( "UniProtKB:O15353") Annotation( ) "WHN") -AnnotationAssertion( "PR:O15353") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "forkhead box protein N1 (human)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (tumor necrosis factor receptor superfamily member 11A (mouse)) - -AnnotationAssertion(Annotation( "OMA:O35305") Annotation( "PRO:DNx") "A tumor necrosis factor receptor superfamily member 11A that is encoded in the genome of mouse.") -AnnotationAssertion( "UniProtKB:O35305") -AnnotationAssertion(Annotation( "UniProtKB:O35305") "CD265 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:O35305") "ODFR (mouse)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mTNFRSF11A") -AnnotationAssertion(Annotation( "UniProtKB:O35305") "osteoclast differentiation factor receptor (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:O35305") "receptor activator of NF-KB (mouse)") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:O35305") Annotation( ) "Rank") -AnnotationAssertion(Annotation( "UniProtKB:O35305") Annotation( ) "Tnfrsf11a") -AnnotationAssertion( "PR:O35305") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "tumor necrosis factor receptor superfamily member 11A (mouse)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (prominin-1 (human)) - -AnnotationAssertion(Annotation( "PRO:CNA") Annotation( "UniProtKB:O43490") "A prominin-1 that is encoded in the genome of human.") -AnnotationAssertion( "UniProtKB:O43490") -AnnotationAssertion(Annotation( "UniProtKB:O43490") "CD133 (human)") -AnnotationAssertion(Annotation( "UniProtKB:O43490") "antigen AC133 (human)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hPROM1") -AnnotationAssertion(Annotation( "UniProtKB:O43490") "prominin-like protein 1 (human)") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:O43490") Annotation( ) "MSTP061") -AnnotationAssertion(Annotation( "UniProtKB:O43490") Annotation( ) "PROM1") -AnnotationAssertion(Annotation( "UniProtKB:O43490") Annotation( ) "PROML1") -AnnotationAssertion( "PR:O43490") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "prominin-1 (human)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (prominin-1 (mouse)) - -AnnotationAssertion(Annotation( "OMA:O54990") Annotation( "PRO:DNx") "A prominin-1 that is encoded in the genome of mouse.") -AnnotationAssertion( "UniProtKB:O54990") -AnnotationAssertion(Annotation( "UniProtKB:O54990") "CD133 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:O54990") "antigen AC133 homolog (mouse)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mPROM1") -AnnotationAssertion(Annotation( "UniProtKB:O54990") "prominin-like protein 1 (mouse)") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:O54990") Annotation( ) "Prom") -AnnotationAssertion(Annotation( "UniProtKB:O54990") Annotation( ) "Prom1") -AnnotationAssertion(Annotation( "UniProtKB:O54990") Annotation( ) "Proml1") -AnnotationAssertion( "PR:O54990") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "prominin-1 (mouse)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (complement component C1q receptor (mouse)) - -AnnotationAssertion(Annotation( "OMA:O89103") Annotation( "PRO:DNx") "A complement component C1q receptor that is encoded in the genome of mouse.") -AnnotationAssertion( "UniProtKB:O89103") -AnnotationAssertion(Annotation( "UniProtKB:O89103") "C1q/MBL/SPA receptor (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:O89103") "C1qR(p) (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:O89103") "C1qRp (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:O89103") "CD93 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:O89103") "Ly-68 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:O89103") "cell surface antigen AA4 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:O89103") "complement component 1 q subcomponent receptor 1 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:O89103") "lymphocyte antigen 68 (mouse)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mCD93") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:O89103") Annotation( ) "Aa4") -AnnotationAssertion(Annotation( "UniProtKB:O89103") Annotation( ) "C1qr1") -AnnotationAssertion(Annotation( "UniProtKB:O89103") Annotation( ) "C1qrp") -AnnotationAssertion(Annotation( "UniProtKB:O89103") Annotation( ) "Cd93") -AnnotationAssertion(Annotation( "UniProtKB:O89103") Annotation( ) "Ly68") -AnnotationAssertion( "PR:O89103") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "complement component C1q receptor (mouse)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (renin (human)) - -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( "UniProtKB:P00797") "A renin that is encoded in the genome of human.") -AnnotationAssertion( "UniProtKB:P00797") -AnnotationAssertion(Annotation( "UniProtKB:P00797") "angiotensinogenase (human)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hREN") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P00797") Annotation( ) "REN") -AnnotationAssertion( "PR:P00797") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "renin (human)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (protein c-Fos (human)) - -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( "UniProtKB:P01100") "A protein c-Fos that is encoded in the genome of human.") -AnnotationAssertion(Annotation(rdfs:label "PR:P01100 located_in GO:0005654") "Reactome:R-HSA-450216") -AnnotationAssertion( "UniProtKB:P01100") -AnnotationAssertion(Annotation( "UniProtKB:P01100") "Fos proto-oncogene, AP-1 transcription factor subunit (human)") -AnnotationAssertion(Annotation( "UniProtKB:P01100") "G0/G1 switch regulatory protein 7 (human)") -AnnotationAssertion(Annotation( "UniProtKB:P01100") "cellular oncogene fos (human)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hFOS") -AnnotationAssertion(Annotation( "UniProtKB:P01100") "proto-oncogene c-Fos (human)") -AnnotationAssertion(Annotation( "UniProtKB:P01100") "transcription factor AP-1 subunit c-Fos (human)") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P01100") Annotation( ) "FOS") -AnnotationAssertion(Annotation( "UniProtKB:P01100") Annotation( ) "G0S7") -AnnotationAssertion( "PR:P01100") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "protein c-Fos (human)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (protein c-Fos (mouse)) - -AnnotationAssertion(Annotation( "OMA:P01101") Annotation( "PRO:DNx") "A protein c-Fos that is encoded in the genome of mouse.") -AnnotationAssertion( "UniProtKB:P01101") -AnnotationAssertion(Annotation( "UniProtKB:P01101") "FBJ osteosarcoma oncogene (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P01101") "cellular oncogene fos (mouse)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mFOS") -AnnotationAssertion(Annotation( "UniProtKB:P01101") "transcription factor AP-1 subunit c-Fos (mouse)") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P01101") Annotation( ) "Fos") -AnnotationAssertion( "PR:P01101") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "protein c-Fos (mouse)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (prolactin (human)) - -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( "UniProtKB:P01236") "A prolactin that is encoded in the genome of human.") -AnnotationAssertion( "UniProtKB:P01236") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hPRL") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P01236") Annotation( ) "PRL") -AnnotationAssertion( "PR:P01236") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "prolactin (human)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (thyroglobulin (human)) - -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( "UniProtKB:P01266") "A thyroglobulin that is encoded in the genome of human.") -AnnotationAssertion( "UniProtKB:P01266") -AnnotationAssertion(Annotation( "UniProtKB:P01266") "Tg (human)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hTG") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P01266") Annotation( ) "TG") -AnnotationAssertion( "PR:P01266") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "thyroglobulin (human)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (insulin gene translation product (human)) - -AnnotationAssertion(Annotation( "PRO:DAN") Annotation( "UniProtKB:P01308") "An insulin gene translation product that is encoded in the genome of human.") -AnnotationAssertion( "UniProtKB:P01308") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hINS") -AnnotationAssertion( "protein") -AnnotationAssertion( "PR:P01308") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "insulin gene translation product (human)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (interleukin-2 receptor subunit alpha (human)) - -AnnotationAssertion(Annotation( "PRO:CNA") Annotation( "UniProtKB:P01589") "An interleukin-2 receptor subunit alpha that is encoded in the genome of human.") -AnnotationAssertion(Annotation( "UniProtKB:P01589") "p55 (human)") -AnnotationAssertion( "UniProtKB:P01589") -AnnotationAssertion(Annotation( "UniProtKB:P01589") "CD25 (human)") -AnnotationAssertion(Annotation( "UniProtKB:P01589") "IL-2 receptor subunit alpha (human)") -AnnotationAssertion(Annotation( "UniProtKB:P01589") "IL-2-RA (human)") -AnnotationAssertion(Annotation( "UniProtKB:P01589") "IL-2R subunit alpha (human)") -AnnotationAssertion(Annotation( "UniProtKB:P01589") "IL2-RA (human)") -AnnotationAssertion(Annotation( "UniProtKB:P01589") "TAC antigen (human)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hIL2RA") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P01589") Annotation( ) "IL2RA") -AnnotationAssertion( "PR:P01589") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "interleukin-2 receptor subunit alpha (human)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (interleukin-2 receptor subunit alpha (mouse)) - -AnnotationAssertion(Annotation( "OMA:P01590") Annotation( "PRO:DNx") "An interleukin-2 receptor subunit alpha that is encoded in the genome of mouse.") -AnnotationAssertion(Annotation( "UniProtKB:P01590") "p55 (mouse)") -AnnotationAssertion( "UniProtKB:P01590") -AnnotationAssertion(Annotation( "UniProtKB:P01590") "CD25 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P01590") "IL-2 receptor subunit alpha (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P01590") "IL-2-RA (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P01590") "IL-2R subunit alpha (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P01590") "IL2-RA (mouse)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mIL2RA") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P01590") Annotation( ) "Il2r") -AnnotationAssertion(Annotation( "UniProtKB:P01590") Annotation( ) "Il2ra") -AnnotationAssertion( "PR:P01590") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "interleukin-2 receptor subunit alpha (mouse)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (T-cell surface glycoprotein CD4 (human)) - -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( "UniProtKB:P01730") "A CD4 molecule that is encoded in the genome of human.") -AnnotationAssertion( "UniProtKB:P01730") -AnnotationAssertion(Annotation( "UniProtKB:P01730") "T-cell surface antigen T4/Leu-3 (human)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hCD4") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P01730") Annotation( ) "CD4") -AnnotationAssertion( "PR:P01730") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "T-cell surface glycoprotein CD4 (human)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (T-cell surface glycoprotein CD8 alpha chain (mouse)) - -AnnotationAssertion(Annotation( "OMA:P01731") Annotation( "PRO:DNx") "A T-cell surface glycoprotein CD8 alpha chain that is encoded in the genome of mouse.") -AnnotationAssertion( "UniProtKB:P01731") -AnnotationAssertion(Annotation( "UniProtKB:P01731") "CD8a (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P01731") "T-cell surface glycoprotein Lyt-2 (mouse)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mCD8A") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P01731") Annotation( ) "Cd8a") -AnnotationAssertion(Annotation( "UniProtKB:P01731") Annotation( ) "Lyt-2") -AnnotationAssertion(Annotation( "UniProtKB:P01731") Annotation( ) "Lyt2") -AnnotationAssertion( "PR:P01731") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "T-cell surface glycoprotein CD8 alpha chain (mouse)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (T-cell surface glycoprotein CD8 alpha chain (human)) - -AnnotationAssertion(Annotation( "PRO:CNA") Annotation( "UniProtKB:P01732") "A T-cell surface glycoprotein CD8 alpha chain that is encoded in the genome of human.") -AnnotationAssertion( "UniProtKB:P01732") -AnnotationAssertion(Annotation( "UniProtKB:P01732") "CD8a (human)") -AnnotationAssertion(Annotation( "UniProtKB:P01732") "T-lymphocyte differentiation antigen T8/Leu-2 (human)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hCD8A") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P01732") Annotation( ) "CD8A") -AnnotationAssertion(Annotation( "UniProtKB:P01732") Annotation( ) "MAL") -AnnotationAssertion( "PR:P01732") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "T-cell surface glycoprotein CD8 alpha chain (human)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (Thy-1 membrane glycoprotein (mouse)) - -AnnotationAssertion(Annotation( "OMA:P01831") Annotation( "PRO:DNx") "A Thy-1 membrane glycoprotein that is encoded in the genome of mouse.") -AnnotationAssertion( "UniProtKB:P01831") -AnnotationAssertion(Annotation( "UniProtKB:P01831") "CD90 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P01831") "Thy-1 antigen (mouse)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mTHY1") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P01831") Annotation( ) "Thy-1") -AnnotationAssertion(Annotation( "UniProtKB:P01831") Annotation( ) "Thy1") -AnnotationAssertion( "PR:P01831") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "Thy-1 membrane glycoprotein (mouse)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (myelin basic protein (human)) - -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( "UniProtKB:P02686") "A myelin basic protein that is encoded in the genome of human.") -AnnotationAssertion(Annotation(rdfs:label "PR:P02686 located_in GO:0005829") "Reactome:R-HSA-9614770") -AnnotationAssertion( "UniProtKB:P02686") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hMBP") -AnnotationAssertion(Annotation( "UniProtKB:P02686") "myelin A1 protein (human)") -AnnotationAssertion(Annotation( "UniProtKB:P02686") "myelin membrane encephalitogenic protein (human)") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P02686") Annotation( ) "MBP") -AnnotationAssertion( "PR:P02686") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "myelin basic protein (human)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (glycophorin-A (human)) - -AnnotationAssertion(Annotation( "PRO:CNA") Annotation( "UniProtKB:P02724") "A glycophorin-A that is encoded in the genome of human.") -AnnotationAssertion( "UniProtKB:P02724") -AnnotationAssertion(Annotation( "UniProtKB:P02724") "CD235a (human)") -AnnotationAssertion(Annotation( "UniProtKB:P02724") "MN sialoglycoprotein (human)") -AnnotationAssertion(Annotation( "UniProtKB:P02724") "PAS-2 (human)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hGYPA") -AnnotationAssertion(Annotation( "UniProtKB:P02724") "sialoglycoprotein alpha (human)") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P02724") Annotation( ) "GPA") -AnnotationAssertion(Annotation( "UniProtKB:P02724") Annotation( ) "GYPA") -AnnotationAssertion( "PR:P02724") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "glycophorin-A (human)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (transferrin receptor protein 1 (human)) - -AnnotationAssertion(Annotation( "PRO:WCB") Annotation( "UniProtKB:P02786") "A transferrin receptor protein 1 that is encoded in the genome of human.") -AnnotationAssertion(Annotation( "UniProtKB:P02786") "TR (human)") -AnnotationAssertion(Annotation( "UniProtKB:P02786") "p90 (human)") -AnnotationAssertion(Annotation(rdfs:label "PR:P02786 located_in GO:0030659") "Reactome:R-HSA-434196") -AnnotationAssertion(Annotation(rdfs:label "PR:P02786 located_in GO:0000139") "Reactome:R-HSA-434330") -AnnotationAssertion(Annotation(rdfs:label "PR:P02786 located_in GO:0030665") "Reactome:R-HSA-8869124") -AnnotationAssertion(Annotation(rdfs:label "PR:P02786 located_in GO:0010008") "Reactome:R-HSA-8961829") -AnnotationAssertion(Annotation(rdfs:label "PR:P02786 located_in GO:0005886") "Reactome:R-HSA-917983") -AnnotationAssertion( "UniProtKB:P02786") -AnnotationAssertion(Annotation( "UniProtKB:P02786") "CD71 (human)") -AnnotationAssertion(Annotation( "UniProtKB:P02786") "T9 (human)") -AnnotationAssertion(Annotation( "UniProtKB:P02786") "TfR (human)") -AnnotationAssertion(Annotation( "UniProtKB:P02786") "TfR1 (human)") -AnnotationAssertion(Annotation( "UniProtKB:P02786") "Trfr (human)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hTFRC") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P02786") Annotation( ) "TFRC") -AnnotationAssertion( "PR:P02786") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "transferrin receptor protein 1 (human)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (lactotransferrin (human)) - -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( "UniProtKB:P02788") "A lactotransferrin that is encoded in the genome of human.") -AnnotationAssertion( "UniProtKB:P02788") -AnnotationAssertion(Annotation( "UniProtKB:P02788") "growth-inhibiting protein 12 (human)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hLTF") -AnnotationAssertion(Annotation( "UniProtKB:P02788") "lactoferrin (human)") -AnnotationAssertion(Annotation( "UniProtKB:P02788") "talalactoferrin (human)") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P02788") Annotation( ) "GIG12") -AnnotationAssertion(Annotation( "UniProtKB:P02788") Annotation( ) "LF") -AnnotationAssertion(Annotation( "UniProtKB:P02788") Annotation( ) "LTF") -AnnotationAssertion( "PR:P02788") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "lactotransferrin (human)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (glial fibrillary acidic protein (mouse)) - -AnnotationAssertion(Annotation( "OMA:P03995") Annotation( "PRO:DNx") "A glial fibrillary acidic protein that is encoded in the genome of mouse.") -AnnotationAssertion( "UniProtKB:P03995") -AnnotationAssertion(Annotation( "UniProtKB:P03995") "GFAP (mouse)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mGFAP") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P03995") Annotation( ) "Gfap") -AnnotationAssertion( "PR:P03995") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "glial fibrillary acidic protein (mouse)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (DNA nucleotidylexotransferase (human)) - -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( "UniProtKB:P04053") "A DNA nucleotidylexotransferase that is encoded in the genome of human.") -AnnotationAssertion(Annotation( "UniProtKB:P04053") "terminal transferase (human)") -AnnotationAssertion( "UniProtKB:P04053") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hDNTT") -AnnotationAssertion(Annotation( "UniProtKB:P04053") "terminal addition enzyme (human)") -AnnotationAssertion(Annotation( "UniProtKB:P04053") "terminal deoxynucleotidyltransferase (human)") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P04053") Annotation( ) "DNTT") -AnnotationAssertion(Annotation( "UniProtKB:P04053") Annotation( ) "TDT") -AnnotationAssertion( "PR:P04053") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "DNA nucleotidylexotransferase (human)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (Thy-1 membrane glycoprotein (human)) - -AnnotationAssertion(Annotation( "PRO:WCB") Annotation( "UniProtKB:P04216") "A Thy-1 membrane glycoprotein that is encoded in the genome of human.") -AnnotationAssertion( "UniProtKB:P04216") -AnnotationAssertion(Annotation( "UniProtKB:P04216") "CD90 (human)") -AnnotationAssertion(Annotation( "UniProtKB:P04216") "CDw90 (human)") -AnnotationAssertion(Annotation( "UniProtKB:P04216") "Thy-1 antigen (human)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hTHY1") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P04216") Annotation( ) "THY1") -AnnotationAssertion( "PR:P04216") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "Thy-1 membrane glycoprotein (human)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (myelin basic protein (mouse)) - -AnnotationAssertion(Annotation( "OMA:P04370") Annotation( "PRO:DNx") "A myelin basic protein that is encoded in the genome of mouse.") -AnnotationAssertion( "UniProtKB:P04370") -AnnotationAssertion(Annotation( "UniProtKB:P04370") "MBP (mouse)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mMBP") -AnnotationAssertion(Annotation( "UniProtKB:P04370") "myelin A1 protein (mouse)") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P04370") Annotation( ) "Mbp") -AnnotationAssertion(Annotation( "UniProtKB:P04370") Annotation( ) "Shi") -AnnotationAssertion( "PR:P04370") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "myelin basic protein (mouse)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (mast/stem cell growth factor receptor Kit (mouse)) - -AnnotationAssertion(Annotation( "OMA:MOUSE17014") Annotation( "PRO:DNx") "A mast/stem cell growth factor receptor that is encoded in the genome of mouse.") -AnnotationAssertion( "UniProtKB:P05532") -AnnotationAssertion(Annotation( "UniProtKB:P05532") "CD117 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P05532") "SCFR (mouse)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mKIT") -AnnotationAssertion(Annotation( "UniProtKB:P05532") "proto-oncogene c-Kit (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P05532") "tyrosine-protein kinase Kit (mouse)") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P05532") Annotation( ) "Kit") -AnnotationAssertion(Annotation( "UniProtKB:P05532") Annotation( ) "Sl") -AnnotationAssertion( "PR:P05532") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "mast/stem cell growth factor receptor Kit (mouse)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (lymphocyte antigen 6A-2/6E-1 (mouse)) - -AnnotationAssertion(Annotation( "PRO:CNA") Annotation( "UniProtKB:P05533") "A lymphocyte antigen 6A-2/6E-1 that is encoded in the genome of mouse.") -AnnotationAssertion(Annotation( "UniProtKB:P05533") "TAP (mouse)") -AnnotationAssertion( "UniProtKB:P05533") -AnnotationAssertion(Annotation( "UniProtKB:P05533") "Ly-6A.2/Ly-6E.1 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P05533") "SCA-1 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P05533") "Stem cell antigen 1 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P05533") "T-cell-activating protein (mouse)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mLy6a") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P05533") Annotation( ) "Ly6") -AnnotationAssertion(Annotation( "UniProtKB:P05533") Annotation( ) "Ly6a") -AnnotationAssertion( "PR:P05533") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "lymphocyte antigen 6A-2/6E-1 (mouse)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (integrin alpha-M (mouse)) - -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( "UniProtKB:P05555") "An integrin alpha-M that is encoded in the genome of mouse.") -AnnotationAssertion( "UniProtKB:P05555") -AnnotationAssertion(Annotation( "UniProtKB:P05555") "CD11 antigen-like family member B (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P05555") "CD11b (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P05555") "CR-3 alpha chain (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P05555") "cell surface glycoprotein MAC-1 subunit alpha (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P05555") "leukocyte adhesion receptor MO1 (mouse)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mITGAM") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P05555") Annotation( ) "Itgam") -AnnotationAssertion( "PR:P05555") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "integrin alpha-M (mouse)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (T-cell surface glycoprotein CD5 (human)) - -AnnotationAssertion(Annotation( "PRO:WCB") Annotation( "UniProtKB:P06127") "A T-cell surface glycoprotein CD5 that is encoded in the genome of human.") -AnnotationAssertion( "UniProtKB:P06127") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hCD5") -AnnotationAssertion(Annotation( "UniProtKB:P06127") "lymphocyte antigen T1/Leu-1 (human)") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P06127") Annotation( ) "CD5") -AnnotationAssertion(Annotation( "UniProtKB:P06127") Annotation( ) "LEU1") -AnnotationAssertion( "PR:P06127") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "T-cell surface glycoprotein CD5 (human)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (T-cell surface glycoprotein CD4 (mouse)) - -AnnotationAssertion(Annotation( "OMA:P06332") Annotation( "PRO:DNx") "A CD4 molecule that is encoded in the genome of mouse.") -AnnotationAssertion( "UniProtKB:P06332") -AnnotationAssertion(Annotation( "UniProtKB:P06332") "CD4 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P06332") "T-cell differentiation antigen L3T4 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P06332") "T-cell surface antigen T4/Leu-3 (mouse)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mCD4") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P06332") Annotation( ) "Cd4") -AnnotationAssertion( "PR:P06332") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "T-cell surface glycoprotein CD4 (mouse)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (T-cell surface antigen CD2 (human)) - -AnnotationAssertion(Annotation( "PRO:CNA") Annotation( "UniProtKB:P06729") "A CD2 molecule that is encoded in the genome of human.") -AnnotationAssertion( "UniProtKB:P06729") -AnnotationAssertion(Annotation( "UniProtKB:P06729") "LFA-2 (human)") -AnnotationAssertion(Annotation( "UniProtKB:P06729") "LFA-3 receptor (human)") -AnnotationAssertion(Annotation( "UniProtKB:P06729") "T-cell surface antigen T11/Leu-5 (human)") -AnnotationAssertion(Annotation( "UniProtKB:P06729") "erythrocyte receptor (human)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hCD2") -AnnotationAssertion(Annotation( "UniProtKB:P06729") "rosette receptor (human)") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P06729") Annotation( ) "CD2") -AnnotationAssertion(Annotation( "UniProtKB:P06729") Annotation( ) "SRBC") -AnnotationAssertion( "PR:P06729") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "T-cell surface antigen CD2 (human)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (low affinity immunoglobulin epsilon Fc receptor (human)) - -AnnotationAssertion(Annotation( "PRO:WCB") Annotation( "UniProtKB:P06734") "A low affinity immunoglobulin epsilon Fc receptor that is encoded in the genome of human.") -AnnotationAssertion(Annotation(rdfs:label "PR:P06734 located_in GO:0005886") "Reactome:R-HSA-2127280") -AnnotationAssertion( "UniProtKB:P06734") -AnnotationAssertion(Annotation( "UniProtKB:P06734") "BLAST-2 (human)") -AnnotationAssertion(Annotation( "UniProtKB:P06734") "C-type lectin domain family 4 member J (human)") -AnnotationAssertion(Annotation( "UniProtKB:P06734") "CD23 (human)") -AnnotationAssertion(Annotation( "UniProtKB:P06734") "Fc-epsilon-RII (human)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hFCER2") -AnnotationAssertion(Annotation( "UniProtKB:P06734") "immunoglobulin E-binding factor (human)") -AnnotationAssertion(Annotation( "UniProtKB:P06734") "lymphocyte IgE receptor (human)") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P06734") Annotation( ) "CD23A") -AnnotationAssertion(Annotation( "UniProtKB:P06734") Annotation( ) "CLEC4J") -AnnotationAssertion(Annotation( "UniProtKB:P06734") Annotation( ) "FCE2") -AnnotationAssertion(Annotation( "UniProtKB:P06734") Annotation( ) "FCER2") -AnnotationAssertion(Annotation( "UniProtKB:P06734") Annotation( ) "IGEBF") -AnnotationAssertion( "PR:P06734") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "low affinity immunoglobulin epsilon Fc receptor (human)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (receptor-type tyrosine-protein phosphatase C (mouse)) - -AnnotationAssertion(Annotation( "OMA:P06800") Annotation( "PRO:DNx") "A receptor-type tyrosine-protein phosphatase C that is encoded in the genome of mouse.") -AnnotationAssertion( "UniProtKB:P06800") -AnnotationAssertion(Annotation( "UniProtKB:P06800") "CD45 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P06800") "L-CA (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P06800") "T200 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P06800") "leukocyte common antigen (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P06800") "lymphocyte antigen 5 (mouse)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mPTPRC") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P06800") Annotation( ) "Ly-5") -AnnotationAssertion(Annotation( "UniProtKB:P06800") Annotation( ) "Ptprc") -AnnotationAssertion( "PR:P06800") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "receptor-type tyrosine-protein phosphatase C (mouse)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (prolactin (mouse)) - -AnnotationAssertion(Annotation( "OMA:P06879") Annotation( "PRO:DNx") "A prolactin that is encoded in the genome of mouse.") -AnnotationAssertion( "UniProtKB:P06879") -AnnotationAssertion(Annotation( "UniProtKB:P06879") "PRL (mouse)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mPRL") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P06879") Annotation( ) "Prl") -AnnotationAssertion( "PR:P06879") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "prolactin (mouse)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (macrophage colony-stimulating factor 1 receptor (human)) - -AnnotationAssertion(Annotation( "PRO:WCB") Annotation( "UniProtKB:P07333") "A macrophage colony-stimulating factor 1 receptor that is encoded in the genome of human.") -AnnotationAssertion( "DTO:03100090") -AnnotationAssertion( "UniProtKB:P07333") -AnnotationAssertion(Annotation( "UniProtKB:P07333") "CD115 (human)") -AnnotationAssertion(Annotation( "UniProtKB:P07333") "CSF-1 receptor (human)") -AnnotationAssertion(Annotation( "UniProtKB:P07333") "CSF-1-R (human)") -AnnotationAssertion(Annotation( "UniProtKB:P07333") "CSF-1R (human)") -AnnotationAssertion(Annotation( "UniProtKB:P07333") "M-CSF-R (human)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hCSF1R") -AnnotationAssertion(Annotation( "UniProtKB:P07333") "proto-oncogene c-Fms (human)") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P07333") Annotation( ) "CSF1R") -AnnotationAssertion(Annotation( "UniProtKB:P07333") Annotation( ) "FMS") -AnnotationAssertion( "PR:P07333") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "macrophage colony-stimulating factor 1 receptor (human)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (T-cell surface glycoprotein CD3 epsilon chain (human)) - -AnnotationAssertion(Annotation( "PRO:CNA") Annotation( "UniProtKB:P07766") "A CD3 epsilon that is encoded in the genome of human.") -AnnotationAssertion( "UniProtKB:P07766") -AnnotationAssertion(Annotation( "UniProtKB:P07766") "CD3e (human)") -AnnotationAssertion(Annotation( "UniProtKB:P07766") "T-cell surface antigen T3/Leu-4 epsilon chain (human)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hCD3E") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P07766") Annotation( ) "CD3E") -AnnotationAssertion(Annotation( "UniProtKB:P07766") Annotation( ) "T3E") -AnnotationAssertion( "PR:P07766") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "T-cell surface glycoprotein CD3 epsilon chain (human)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (lactotransferrin (mouse)) - -AnnotationAssertion(Annotation( "OMA:P08071") Annotation( "PRO:DNx") "A lactotransferrin that is encoded in the genome of mouse.") -AnnotationAssertion( "UniProtKB:P08071") -AnnotationAssertion(Annotation( "UniProtKB:P08071") "lactoferrin (mouse)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mLTF") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P08071") Annotation( ) "Ltf") -AnnotationAssertion( "PR:P08071") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "lactotransferrin (mouse)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (low affinity immunoglobulin gamma Fc region receptor II (mouse)) - -AnnotationAssertion(Annotation( "PRO:CNA") Annotation( "UniProtKB:P08101") "A low affinity immunoglobulin gamma Fc region receptor II that is encoded in the genome of mouse.") -AnnotationAssertion( "UniProtKB:P08101") -AnnotationAssertion(Annotation( "UniProtKB:P08101") "CD32 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P08101") "Fc gamma receptor IIB (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P08101") "Fc-gamma RII (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P08101") "Fc-gamma-RIIB (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P08101") "FcRII (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P08101") "IgG Fc receptor II beta (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P08101") "lymphocyte antigen 17 (mouse)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mFcgr2") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P08101") Annotation( ) "Fcgr2") -AnnotationAssertion(Annotation( "UniProtKB:P08101") Annotation( ) "Fcgr2b") -AnnotationAssertion(Annotation( "UniProtKB:P08101") Annotation( ) "Ly-17") -AnnotationAssertion( "PR:P08101") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "low affinity immunoglobulin gamma Fc region receptor II (mouse)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (neprilysin (human)) - -AnnotationAssertion(Annotation( "PRO:WCB") Annotation( "UniProtKB:P08473") "A neprilysin that is encoded in the genome of human.") -AnnotationAssertion( "UniProtKB:P08473") -AnnotationAssertion(Annotation( "UniProtKB:P08473") "CALLA (human)") -AnnotationAssertion(Annotation( "UniProtKB:P08473") "CD10 (human)") -AnnotationAssertion(Annotation( "UniProtKB:P08473") "NEP (human)") -AnnotationAssertion(Annotation( "UniProtKB:P08473") "SFE (human)") -AnnotationAssertion(Annotation( "UniProtKB:P08473") "atriopeptidase (human)") -AnnotationAssertion(Annotation( "UniProtKB:P08473") "common acute lymphocytic leukemia antigen (human)") -AnnotationAssertion(Annotation( "UniProtKB:P08473") "enkephalinase (human)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hMME") -AnnotationAssertion(Annotation( "UniProtKB:P08473") "neutral endopeptidase (human)") -AnnotationAssertion(Annotation( "UniProtKB:P08473") "neutral endopeptidase 24.11 (human)") -AnnotationAssertion(Annotation( "UniProtKB:P08473") "skin fibroblast elastase (human)") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P08473") Annotation( ) "EPN") -AnnotationAssertion(Annotation( "UniProtKB:P08473") Annotation( ) "MME") -AnnotationAssertion( "PR:P08473") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "neprilysin (human)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (low affinity immunoglobulin gamma Fc region receptor III (mouse)) - -AnnotationAssertion(Annotation( "PRO:CNA") Annotation( "UniProtKB:P08508") "A low affinity immunoglobulin gamma Fc region receptor III that is encoded in the genome of mouse.") -AnnotationAssertion( "UniProtKB:P08508") -AnnotationAssertion(Annotation( "UniProtKB:P08508") "CD16 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P08508") "Fc-gamma RIII (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P08508") "FcRIII (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P08508") "IgG Fc receptor III (mouse)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mFcgr3") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P08508") Annotation( ) "Fcgr3") -AnnotationAssertion( "PR:P08508") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "low affinity immunoglobulin gamma Fc region receptor III (mouse)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (integrin alpha-IIb (human)) - -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( "UniProtKB:P08514") "An integrin alpha-IIb that is encoded in the genome of human.") -AnnotationAssertion( "UniProtKB:P08514") -AnnotationAssertion(Annotation( "UniProtKB:P08514") "CD41 (human)") -AnnotationAssertion(Annotation( "UniProtKB:P08514") "GPIIb (human)") -AnnotationAssertion(Annotation( "UniProtKB:P08514") "GPalpha IIb (human)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hITGA2B") -AnnotationAssertion(Annotation( "UniProtKB:P08514") "platelet membrane glycoprotein IIb (human)") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P08514") Annotation( ) "GP2B") -AnnotationAssertion(Annotation( "UniProtKB:P08514") Annotation( ) "ITGA2B") -AnnotationAssertion(Annotation( "UniProtKB:P08514") Annotation( ) "ITGAB") -AnnotationAssertion( "PR:P08514") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "integrin alpha-IIb (human)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (monocyte differentiation antigen CD14 (human)) - -AnnotationAssertion(Annotation( "PRO:WCB") Annotation( "UniProtKB:P08571") "A CD14 molecule that is encoded in the genome of human.") -AnnotationAssertion( "UniProtKB:P08571") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hCD14") -AnnotationAssertion(Annotation( "UniProtKB:P08571") "myeloid cell-specific leucine-rich glycoprotein (human)") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P08571") Annotation( ) "CD14") -AnnotationAssertion( "PR:P08571") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "monocyte differentiation antigen CD14 (human)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (receptor-type tyrosine-protein phosphatase C (human)) - -AnnotationAssertion(Annotation( "PRO:CNA") Annotation( "UniProtKB:P08575") "A receptor-type tyrosine-protein phosphatase C that is encoded in the genome of human.") -AnnotationAssertion( "UniProtKB:P08575") -AnnotationAssertion(Annotation( "UniProtKB:P08575") "L-CA (human)") -AnnotationAssertion(Annotation( "UniProtKB:P08575") "T200 (human)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hPTPRC") -AnnotationAssertion(Annotation( "UniProtKB:P08575") "leukocyte common antigen (human)") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P08575") Annotation( ) "CD45") -AnnotationAssertion(Annotation( "UniProtKB:P08575") Annotation( ) "PTPRC") -AnnotationAssertion( "PR:P08575") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "receptor-type tyrosine-protein phosphatase C (human)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (receptor-type tyrosine-protein phosphatase C isoform CD45RABC (human)) - -AnnotationAssertion(Annotation( "PRO:DAN") "A receptor-type tyrosine-protein phosphatase C isoform CD45RABC that is encoded in the genome of human.") -AnnotationAssertion( "UniProtKB:P08575-3") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hPTPRC/iso:CD45RABC") -AnnotationAssertion( "protein") -AnnotationAssertion( "PR:P08575-3") -AnnotationAssertion(rdfs:comment "Category=organism-sequence.") -AnnotationAssertion(rdfs:label "receptor-type tyrosine-protein phosphatase C isoform CD45RABC (human)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (receptor-type tyrosine-protein phosphatase C isoform CD45RA (human)) - -AnnotationAssertion(Annotation( "GOC:add") Annotation( "PRO:ADD") Annotation( "PRO:DAN") "A receptor-type tyrosine-protein phosphatase C isoform CD45RA that is encoded in the genome of human.") -AnnotationAssertion( "UniProtKB:P08575-8") -AnnotationAssertion( "CD45RA (human)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hPTPRC/iso:CD45RA") -AnnotationAssertion( "protein") -AnnotationAssertion( "PR:P08575-8") -AnnotationAssertion(rdfs:comment "Category=organism-sequence. Requested by=CL.") -AnnotationAssertion(rdfs:label "receptor-type tyrosine-protein phosphatase C isoform CD45RA (human)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (T-cell surface antigen CD2 (mouse)) - -AnnotationAssertion(Annotation( "OMA:P08920") Annotation( "PRO:DNx") "A CD2 molecule that is encoded in the genome of mouse.") -AnnotationAssertion( "UniProtKB:P08920") -AnnotationAssertion(Annotation( "UniProtKB:P08920") "CD2 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P08920") "LFA-2 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P08920") "LFA-3 receptor (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P08920") "T-cell surface antigen T11/Leu-5 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P08920") "lymphocyte antigen 37 (mouse)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mCD2") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P08920") Annotation( ) "Cd2") -AnnotationAssertion(Annotation( "UniProtKB:P08920") Annotation( ) "Ly-37") -AnnotationAssertion( "PR:P08920") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "T-cell surface antigen CD2 (mouse)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (CD48 antigen (human)) - -AnnotationAssertion(Annotation( "PRO:WCB") Annotation( "UniProtKB:P09326") "A CD48 molecule that is encoded in the genome of human.") -AnnotationAssertion( "UniProtKB:P09326") -AnnotationAssertion(Annotation( "UniProtKB:P09326") "B-lymphocyte activation marker BLAST-1 (human)") -AnnotationAssertion(Annotation( "UniProtKB:P09326") "BCM1 surface antigen (human)") -AnnotationAssertion(Annotation( "UniProtKB:P09326") "SLAM family member 2 (human)") -AnnotationAssertion(Annotation( "UniProtKB:P09326") "SLAMF2 (human)") -AnnotationAssertion(Annotation( "UniProtKB:P09326") "TCT.1 (human)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hCD48") -AnnotationAssertion(Annotation( "UniProtKB:P09326") "leukocyte antigen MEM-102 (human)") -AnnotationAssertion(Annotation( "UniProtKB:P09326") "signaling lymphocytic activation molecule 2 (human)") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P09326") Annotation( ) "BCM1") -AnnotationAssertion(Annotation( "UniProtKB:P09326") Annotation( ) "BLAST1") -AnnotationAssertion(Annotation( "UniProtKB:P09326") Annotation( ) "CD48") -AnnotationAssertion( "PR:P09326") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "CD48 antigen (human)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (T-cell antigen CD7 (human)) - -AnnotationAssertion(Annotation( "PRO:WCB") Annotation( "UniProtKB:P09564") "A CD7 molecule that is encoded in the genome of human.") -AnnotationAssertion( "UniProtKB:P09564") -AnnotationAssertion(Annotation( "UniProtKB:P09564") "GP40 (human)") -AnnotationAssertion(Annotation( "UniProtKB:P09564") "T-cell leukemia antigen (human)") -AnnotationAssertion(Annotation( "UniProtKB:P09564") "T-cell surface antigen Leu-9 (human)") -AnnotationAssertion(Annotation( "UniProtKB:P09564") "TP41 (human)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hCD7") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P09564") Annotation( ) "CD7") -AnnotationAssertion( "PR:P09564") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "T-cell antigen CD7 (human)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (macrophage colony-stimulating factor 1 receptor (mouse)) - -AnnotationAssertion(Annotation( "OMA:P09581") Annotation( "PRO:DNx") "A macrophage colony-stimulating factor 1 receptor that is encoded in the genome of mouse.") -AnnotationAssertion( "UniProtKB:P09581") -AnnotationAssertion(Annotation( "UniProtKB:P09581") "CD115 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P09581") "CSF-1 receptor (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P09581") "CSF-1-R (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P09581") "CSF-1R (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P09581") "M-CSF-R (mouse)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mCSF1R") -AnnotationAssertion(Annotation( "UniProtKB:P09581") "proto-oncogene c-Fms (mouse)") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P09581") Annotation( ) "Csf1r") -AnnotationAssertion(Annotation( "UniProtKB:P09581") Annotation( ) "Csfmr") -AnnotationAssertion(Annotation( "UniProtKB:P09581") Annotation( ) "Fms") -AnnotationAssertion( "PR:P09581") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "macrophage colony-stimulating factor 1 receptor (mouse)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (DNA nucleotidylexotransferase (mouse)) - -AnnotationAssertion(Annotation( "OMA:P09838") Annotation( "PRO:DNx") "A DNA nucleotidylexotransferase that is encoded in the genome of mouse.") -AnnotationAssertion( "UniProtKB:P09838") -AnnotationAssertion(Annotation( "UniProtKB:P09838") "TDT (mouse)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mDNTT") -AnnotationAssertion(Annotation( "UniProtKB:P09838") "terminal addition enzyme (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P09838") "terminal deoxynucleotidyltransferase (mouse)") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P09838") Annotation( ) "Dntt") -AnnotationAssertion(Annotation( "UniProtKB:P09838") Annotation( ) "Tdt") -AnnotationAssertion(Annotation( "UniProtKB:P09838") "terminal transferase (mouse)") -AnnotationAssertion( "PR:P09838") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "DNA nucleotidylexotransferase (mouse)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (lymphocyte antigen 6C2 (mouse)) - -AnnotationAssertion(Annotation( "PRO:CNA") Annotation( "UniProtKB:P0CW03") "A lymphocyte antigen 6C2 that is encoded in the genome of mouse.") -AnnotationAssertion( "UniProtKB:P0CW03") -AnnotationAssertion(Annotation( "UniProtKB:P0CW03") "Ly-6C2 (mouse)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mLy6c2") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P0CW03") Annotation( ) "Ly6c") -AnnotationAssertion(Annotation( "UniProtKB:P0CW03") Annotation( ) "Ly6c2") -AnnotationAssertion( "PR:P0CW03") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "lymphocyte antigen 6C2 (mouse)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (mast/stem cell growth factor receptor Kit (human)) - -AnnotationAssertion(Annotation( "PRO:WCB") Annotation( "UniProtKB:P10721") "A mast/stem cell growth factor receptor that is encoded in the genome of human.") -AnnotationAssertion( "DTO:03100231") -AnnotationAssertion( "UniProtKB:P10721") -AnnotationAssertion(Annotation( "UniProtKB:P10721") "CD117 (human)") -AnnotationAssertion(Annotation( "UniProtKB:P10721") "PBT (human)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hKIT") -AnnotationAssertion(Annotation( "UniProtKB:P10721") "p145 c-kit (human)") -AnnotationAssertion(Annotation( "UniProtKB:P10721") "piebald trait protein (human)") -AnnotationAssertion(Annotation( "UniProtKB:P10721") "proto-oncogene c-Kit (human)") -AnnotationAssertion(Annotation( "UniProtKB:P10721") "tyrosine-protein kinase Kit (human)") -AnnotationAssertion(Annotation( "UniProtKB:P10721") "v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog (human)") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P10721") Annotation( ) "KIT") -AnnotationAssertion(Annotation( "UniProtKB:P10721") Annotation( ) "SCFR") -AnnotationAssertion( "PR:P10721") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "mast/stem cell growth factor receptor Kit (human)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (monocyte differentiation antigen CD14 (mouse)) - -AnnotationAssertion(Annotation( "OMA:P10810") Annotation( "PRO:WCB") "A CD14 molecule that is encoded in the genome of mouse.") -AnnotationAssertion( "UniProtKB:P10810") -AnnotationAssertion(Annotation( "UniProtKB:P10810") "CD14 (mouse)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mCD14") -AnnotationAssertion(Annotation( "UniProtKB:P10810") "myeloid cell-specific leucine-rich glycoprotein (mouse)") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P10810") Annotation( ) "Cd14") -AnnotationAssertion( "PR:P10810") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "monocyte differentiation antigen CD14 (mouse)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (integrin alpha-M (human)) - -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( "UniProtKB:P11215") "An integrin alpha-M that is encoded in the genome of human.") -AnnotationAssertion( "UniProtKB:P11215") -AnnotationAssertion(Annotation( "UniProtKB:P11215") "CD11 antigen-like family member B (human)") -AnnotationAssertion(Annotation( "UniProtKB:P11215") "CR-3 alpha chain (human)") -AnnotationAssertion(Annotation( "UniProtKB:P11215") "cell surface glycoprotein MAC-1 subunit alpha (human)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hITGAM") -AnnotationAssertion(Annotation( "UniProtKB:P11215") "leukocyte adhesion receptor MO1 (human)") -AnnotationAssertion(Annotation( "UniProtKB:P11215") "neutrophil adherence receptor (human)") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P11215") Annotation( ) "CD11B") -AnnotationAssertion(Annotation( "UniProtKB:P11215") Annotation( ) "CR3A") -AnnotationAssertion(Annotation( "UniProtKB:P11215") Annotation( ) "ITGAM") -AnnotationAssertion( "PR:P11215") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "integrin alpha-M (human)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (B-lymphocyte antigen CD20 (human)) - -AnnotationAssertion(Annotation( "PRO:WCB") Annotation( "UniProtKB:P11836") "A membrane-spanning 4-domains subfamily A member 1 that is encoded in the genome of human.") -AnnotationAssertion( "UniProtKB:P11836") -AnnotationAssertion(Annotation( "UniProtKB:P11836") "B-lymphocyte surface antigen B1 (human)") -AnnotationAssertion(Annotation( "UniProtKB:P11836") "Bp35 (human)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hMS4A1") -AnnotationAssertion(Annotation( "UniProtKB:P11836") "leukocyte surface antigen Leu-16 (human)") -AnnotationAssertion(Annotation( "UniProtKB:P11836") "membrane-spanning 4-domains subfamily A member 1 (human)") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P11836") Annotation( ) "CD20") -AnnotationAssertion(Annotation( "UniProtKB:P11836") Annotation( ) "MS4A1") -AnnotationAssertion( "PR:P11836") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "B-lymphocyte antigen CD20 (human)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (protein c-Fos (chicken)) - -AnnotationAssertion(Annotation( "OMA:P11939") Annotation( "PRO:DNx") "A protein c-Fos that is encoded in the genome of chicken.") -AnnotationAssertion( "UniProtKB:P11939") -AnnotationAssertion(Annotation( "UniProtKB:P11939") "cellular oncogene fos (chicken)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "chick-FOS") -AnnotationAssertion(Annotation( "UniProtKB:P11939") "transcription factor AP-1 subunit c-Fos (chicken)") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P11939") Annotation( ) "FOS") -AnnotationAssertion( "PR:P11939") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "protein c-Fos (chicken)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (immunoglobulin iota chain (human)) - -AnnotationAssertion(Annotation( "PRO:WCB") Annotation( "UniProtKB:P12018") "An immunoglobulin iota chain that is encoded in the genome of human.") -AnnotationAssertion( "UniProtKB:P12018") -AnnotationAssertion(Annotation( "UniProtKB:P12018") "CD179 antigen-like family member A (human)") -AnnotationAssertion(Annotation( "UniProtKB:P12018") "CD179a (human)") -AnnotationAssertion(Annotation( "UniProtKB:P12018") "V(pre)B protein (human)") -AnnotationAssertion(Annotation( "UniProtKB:P12018") "VpreB protein (human)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hVPREB1") -AnnotationAssertion(Annotation( "UniProtKB:P12018") "protein VPreB1 (human)") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P12018") Annotation( ) "VPREB") -AnnotationAssertion(Annotation( "UniProtKB:P12018") Annotation( ) "VPREB1") -AnnotationAssertion( "PR:P12018") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "immunoglobulin iota chain (human)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (T-cell surface glycoprotein CD5 (mouse)) - -AnnotationAssertion(Annotation( "OMA:P13379") Annotation( "PRO:DNx") "A T-cell surface glycoprotein CD5 that is encoded in the genome of mouse.") -AnnotationAssertion( "UniProtKB:P13379") -AnnotationAssertion(Annotation( "UniProtKB:P13379") "CD5 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P13379") "Lyt-1 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P13379") "lymphocyte antigen 1 (mouse)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mCD5") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P13379") Annotation( ) "Cd5") -AnnotationAssertion(Annotation( "UniProtKB:P13379") Annotation( ) "Ly-1") -AnnotationAssertion( "PR:P13379") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "T-cell surface glycoprotein CD5 (mouse)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (neural cell adhesion molecule 1 (chicken)) - -AnnotationAssertion(Annotation( "OMA:P13590") Annotation( "PRO:CNA") "A neural cell adhesion molecule 1 that is encoded in the genome of chicken.") -AnnotationAssertion( "UniProtKB:P13590") -AnnotationAssertion(Annotation( "UniProtKB:P13590") "N-CAM-1 (chicken)") -AnnotationAssertion(Annotation( "UniProtKB:P13590") "NCAM-1 (chicken)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "chick-NCAM1") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P13590") Annotation( ) "NCAM1") -AnnotationAssertion( "PR:P13590") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "neural cell adhesion molecule 1 (chicken)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (neural cell adhesion molecule 1 (human)) - -AnnotationAssertion(Annotation( "PRO:CNA") Annotation( "UniProtKB:P13591") "A neural cell adhesion molecule 1 that is encoded in the genome of human.") -AnnotationAssertion( "UniProtKB:P13591") -AnnotationAssertion(Annotation( "UniProtKB:P13591") "CD56 (human)") -AnnotationAssertion(Annotation( "UniProtKB:P13591") "N-CAM-1 (human)") -AnnotationAssertion(Annotation( "UniProtKB:P13591") "NCAM-1 (human)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hNCAM1") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P13591") Annotation( ) "NCAM") -AnnotationAssertion(Annotation( "UniProtKB:P13591") Annotation( ) "NCAM1") -AnnotationAssertion( "PR:P13591") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "neural cell adhesion molecule 1 (human)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (neural cell adhesion molecule 1 (mouse)) - -AnnotationAssertion(Annotation( "OMA:P13595") Annotation( "PRO:DNx") "A neural cell adhesion molecule 1 that is encoded in the genome of mouse.") -AnnotationAssertion( "UniProtKB:P13595") -AnnotationAssertion(Annotation( "UniProtKB:P13595") "CD56 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P13595") "N-CAM-1 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P13595") "NCAM-1 (mouse)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mNCAM1") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P13595") Annotation( ) "Ncam") -AnnotationAssertion(Annotation( "UniProtKB:P13595") Annotation( ) "Ncam1") -AnnotationAssertion( "PR:P13595") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "neural cell adhesion molecule 1 (mouse)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (tartrate-resistant acid phosphatase type 5 (human)) - -AnnotationAssertion(Annotation( "PRO:WCB") Annotation( "UniProtKB:P13686") "A tartrate-resistant acid phosphatase type 5 that is encoded in the genome of human.") -AnnotationAssertion( "UniProtKB:P13686") -AnnotationAssertion(Annotation( "UniProtKB:P13686") "TR-AP (human)") -AnnotationAssertion(Annotation( "UniProtKB:P13686") "TrATPase (human)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hACP5") -AnnotationAssertion(Annotation( "UniProtKB:P13686") "tartrate-resistant acid ATPase (human)") -AnnotationAssertion(Annotation( "UniProtKB:P13686") "type 5 acid phosphatase (human)") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P13686") Annotation( ) "ACP5") -AnnotationAssertion( "PR:P13686") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "tartrate-resistant acid phosphatase type 5 (human)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (glial fibrillary acidic protein (human)) - -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( "UniProtKB:P14136") "A glial fibrillary acidic protein that is encoded in the genome of human.") -AnnotationAssertion(Annotation(rdfs:label "PR:P14136 located_in GO:0005829") "Reactome:R-HSA-1253311") -AnnotationAssertion(Annotation(rdfs:label "PR:P14136 located_in GO:0005765") "Reactome:R-HSA-9625195") -AnnotationAssertion( "UniProtKB:P14136") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hGFAP") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P14136") Annotation( ) "GFAP") -AnnotationAssertion( "PR:P14136") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "glial fibrillary acidic protein (human)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (prolactin (chicken)) - -AnnotationAssertion(Annotation( "OMA:P14676") Annotation( "PANTHER:PTHR11417:SF4") Annotation( "PRO:DNx") "A prolactin that is encoded in the genome of chicken.") -AnnotationAssertion( "UniProtKB:P14676") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "chick-PRL") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P14676") Annotation( ) "PRL") -AnnotationAssertion( "PR:P14676") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "prolactin (chicken)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (CD44 antigen (mouse)) - -AnnotationAssertion(Annotation( "OMA:P15379") Annotation( "PRO:WCB") "A CD44 molecule that is encoded in the genome of mouse.") -AnnotationAssertion( "UniProtKB:P15379") -AnnotationAssertion(Annotation( "UniProtKB:P15379") "CD44 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P15379") "ECMR-III (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P15379") "GP90 lymphocyte homing/adhesion receptor (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P15379") "HUTCH-I (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P15379") "PGP-1 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P15379") "PGP-I (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P15379") "extracellular matrix receptor III (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P15379") "hermes antigen (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P15379") "hyaluronate receptor (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P15379") "lymphocyte antigen 24 (mouse)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mCD44") -AnnotationAssertion(Annotation( "UniProtKB:P15379") "phagocytic glycoprotein 1 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P15379") "phagocytic glycoprotein I (mouse)") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P15379") Annotation( ) "Cd44") -AnnotationAssertion(Annotation( "UniProtKB:P15379") Annotation( ) "Ly-24") -AnnotationAssertion( "PR:P15379") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "CD44 antigen (mouse)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (B-lymphocyte antigen CD19 (human)) - -AnnotationAssertion( "A CD19 molecule that is encoded in the genome of human.") -AnnotationAssertion( "UniProtKB:P15391") -AnnotationAssertion(Annotation( "UniProtKB:P15391") "B-lymphocyte surface antigen B4 (human)") -AnnotationAssertion(Annotation( "UniProtKB:P15391") "T-cell surface antigen Leu-12 (human)") -AnnotationAssertion(Annotation( "UniProtKB:P15391") "differentiation antigen CD19 (human)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hCD19") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P15391") Annotation( ) "CD19") -AnnotationAssertion( "PR:P15391") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "B-lymphocyte antigen CD19 (human)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (leukosialin (mouse)) - -AnnotationAssertion(Annotation( "OMA:P15702") Annotation( "PRO:DNx") "A leukosialin that is encoded in the genome of mouse.") -AnnotationAssertion( "UniProtKB:P15702") -AnnotationAssertion(Annotation( "UniProtKB:P15702") "B-cell differentiation antigen LP-3 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P15702") "CD43 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P15702") "Ly-48 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P15702") "leukocyte sialoglycoprotein (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P15702") "lymphocyte antigen 48 (mouse)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mSPN") -AnnotationAssertion(Annotation( "UniProtKB:P15702") "sialophorin (mouse)") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P15702") Annotation( ) "Spn") -AnnotationAssertion( "PR:P15702") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "leukosialin (mouse)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (myelin basic protein (chicken)) - -AnnotationAssertion(Annotation( "PANTHER:PTHR11429:SF0") Annotation( "PRO:DNx") "A myelin basic protein that is encoded in the genome of chicken.") -AnnotationAssertion( "UniProtKB:P15720") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "chick-MBP") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P15720") Annotation( ) "MBP") -AnnotationAssertion( "PR:P15720") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "myelin basic protein (chicken)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (immunoglobulin lambda-like polypeptide 1 (human)) - -AnnotationAssertion(Annotation( "PRO:WCB") Annotation( "UniProtKB:P15814") "An immunoglobulin lambda-like polypeptide 1 that is encoded in the genome of human.") -AnnotationAssertion( "UniProtKB:P15814") -AnnotationAssertion(Annotation( "UniProtKB:P15814") "CD179 antigen-like family member B (human)") -AnnotationAssertion(Annotation( "UniProtKB:P15814") "CD179b (human)") -AnnotationAssertion(Annotation( "UniProtKB:P15814") "Ig lambda-5 (human)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hIGLL1") -AnnotationAssertion(Annotation( "UniProtKB:P15814") "immunoglobulin omega polypeptide (human)") -AnnotationAssertion(Annotation( "UniProtKB:P15814") "immunoglobulin-related protein 14.1 (human)") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P15814") Annotation( ) "IGL1") -AnnotationAssertion(Annotation( "UniProtKB:P15814") Annotation( ) "IGLL1") -AnnotationAssertion( "PR:P15814") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "immunoglobulin lambda-like polypeptide 1 (human)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (V(D)J recombination-activating protein 1 (human)) - -AnnotationAssertion(Annotation( "PRO:CNA") Annotation( "UniProtKB:P15918") "A V(D)J recombination-activating protein 1 that is encoded in the genome of human.") -AnnotationAssertion(Annotation(rdfs:label "PR:P15918 located_in GO:0005654") "Reactome:R-HSA-5692681") -AnnotationAssertion( "UniProtKB:P15918") -AnnotationAssertion(Annotation( "UniProtKB:P15918") "RAG-1 (human)") -AnnotationAssertion(Annotation( "UniProtKB:P15918") "RING finger protein 74 (human)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hRAG1") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P15918") Annotation( ) "RAG1") -AnnotationAssertion(Annotation( "UniProtKB:P15918") Annotation( ) "RNF74") -AnnotationAssertion( "PR:P15918") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "V(D)J recombination-activating protein 1 (human)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (V(D)J recombination-activating protein 1 (mouse)) - -AnnotationAssertion(Annotation( "OMA:P15919") Annotation( "PRO:DNx") "A V(D)J recombination-activating protein 1 that is encoded in the genome of mouse.") -AnnotationAssertion( "UniProtKB:P15919") -AnnotationAssertion(Annotation( "UniProtKB:P15919") "RAG-1 (mouse)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mRAG1") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P15919") Annotation( ) "Rag1") -AnnotationAssertion( "PR:P15919") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "V(D)J recombination-activating protein 1 (mouse)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (erythroid transcription factor (human)) - -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( "UniProtKB:P15976") "An erythroid transcription factor that is encoded in the genome of human.") -AnnotationAssertion(Annotation( "UniProtKB:P15976") "GF-1 (human)") -AnnotationAssertion(Annotation(rdfs:label "PR:P15976 located_in GO:0005654") "Reactome:R-HSA-996772") -AnnotationAssertion( "UniProtKB:P15976") -AnnotationAssertion(Annotation( "UniProtKB:P15976") "GATA-1 (human)") -AnnotationAssertion(Annotation( "UniProtKB:P15976") "GATA-binding factor 1 (human)") -AnnotationAssertion(Annotation( "UniProtKB:P15976") "NF-E1 DNA-binding protein (human)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hGATA1") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P15976") Annotation( ) "ERYF1") -AnnotationAssertion(Annotation( "UniProtKB:P15976") Annotation( ) "GATA1") -AnnotationAssertion(Annotation( "UniProtKB:P15976") Annotation( ) "GF1") -AnnotationAssertion( "PR:P15976") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "erythroid transcription factor (human)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (CD44 antigen (human)) - -AnnotationAssertion(Annotation( "PRO:WCB") Annotation( "UniProtKB:P16070") "A CD44 molecule that is encoded in the genome of human.") -AnnotationAssertion(Annotation( "UniProtKB:P16070") "PGP-I (human)") -AnnotationAssertion( "UniProtKB:P16070") -AnnotationAssertion(Annotation( "UniProtKB:P16070") "CDw44 (human)") -AnnotationAssertion(Annotation( "UniProtKB:P16070") "ECMR-III (human)") -AnnotationAssertion(Annotation( "UniProtKB:P16070") "GP90 lymphocyte homing/adhesion receptor (human)") -AnnotationAssertion(Annotation( "UniProtKB:P16070") "HUTCH-I (human)") -AnnotationAssertion(Annotation( "UniProtKB:P16070") "PGP-1 (human)") -AnnotationAssertion(Annotation( "UniProtKB:P16070") "epican (human)") -AnnotationAssertion(Annotation( "UniProtKB:P16070") "extracellular matrix receptor III (human)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hCD44") -AnnotationAssertion(Annotation( "UniProtKB:P16070") "heparan sulfate proteoglycan (human)") -AnnotationAssertion(Annotation( "UniProtKB:P16070") "hermes antigen (human)") -AnnotationAssertion(Annotation( "UniProtKB:P16070") "hyaluronate receptor (human)") -AnnotationAssertion(Annotation( "UniProtKB:P16070") "phagocytic glycoprotein 1 (human)") -AnnotationAssertion(Annotation( "UniProtKB:P16070") "phagocytic glycoprotein I (human)") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P16070") Annotation( ) "CD44") -AnnotationAssertion(Annotation( "UniProtKB:P16070") Annotation( ) "LHR") -AnnotationAssertion(Annotation( "UniProtKB:P16070") Annotation( ) "MDU2") -AnnotationAssertion(Annotation( "UniProtKB:P16070") Annotation( ) "MDU3") -AnnotationAssertion(Annotation( "UniProtKB:P16070") Annotation( ) "MIC4") -AnnotationAssertion( "PR:P16070") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "CD44 antigen (human)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (leukosialin (human)) - -AnnotationAssertion(Annotation( "PRO:WCB") Annotation( "UniProtKB:P16150") "A leukosialin that is encoded in the genome of human.") -AnnotationAssertion( "UniProtKB:P16150") -AnnotationAssertion(Annotation( "UniProtKB:P16150") "GALGP (human)") -AnnotationAssertion(Annotation( "UniProtKB:P16150") "GPL115 (human)") -AnnotationAssertion(Annotation( "UniProtKB:P16150") "galactoglycoprotein (human)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hSPN") -AnnotationAssertion(Annotation( "UniProtKB:P16150") "leukocyte sialoglycoprotein (human)") -AnnotationAssertion(Annotation( "UniProtKB:P16150") "sialophorin (human)") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P16150") Annotation( ) "CD43") -AnnotationAssertion(Annotation( "UniProtKB:P16150") Annotation( ) "SPN") -AnnotationAssertion( "PR:P16150") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "leukosialin (human)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (glutamyl aminopeptidase (mouse)) - -AnnotationAssertion(Annotation( "OMA:P16406") Annotation( "PRO:DNx") "A glutamyl aminopeptidase that is encoded in the genome of mouse.") -AnnotationAssertion(Annotation( "UniProtKB:P16406") "EAP (mouse)") -AnnotationAssertion( "UniProtKB:P16406") -AnnotationAssertion(Annotation( "UniProtKB:P16406") "AP-A (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P16406") "BP-1/6C3 antigen (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P16406") "CD249 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P16406") "aminopeptidase A (mouse)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mENPEP") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P16406") Annotation( ) "Enpep") -AnnotationAssertion( "PR:P16406") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "glutamyl aminopeptidase (mouse)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (interleukin-7 receptor subunit alpha (human)) - -AnnotationAssertion(Annotation( "PRO:WCB") Annotation( "UniProtKB:P16871") "An interleukin-7 receptor subunit alpha that is encoded in the genome of human.") -AnnotationAssertion( "UniProtKB:P16871") -AnnotationAssertion(Annotation( "UniProtKB:P16871") "CD127 (human)") -AnnotationAssertion(Annotation( "UniProtKB:P16871") "CDw127 (human)") -AnnotationAssertion(Annotation( "UniProtKB:P16871") "IL-7 receptor subunit alpha (human)") -AnnotationAssertion(Annotation( "UniProtKB:P16871") "IL-7R subunit alpha (human)") -AnnotationAssertion(Annotation( "UniProtKB:P16871") "IL-7R-alpha (human)") -AnnotationAssertion(Annotation( "UniProtKB:P16871") "IL-7RA (human)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hIL7R") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P16871") Annotation( ) "IL7R") -AnnotationAssertion( "PR:P16871") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "interleukin-7 receptor subunit alpha (human)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (interleukin-7 receptor subunit alpha (mouse)) - -AnnotationAssertion(Annotation( "OMA:P16872") Annotation( "PRO:DNx") "An interleukin-7 receptor subunit alpha that is encoded in the genome of mouse.") -AnnotationAssertion( "UniProtKB:P16872") -AnnotationAssertion(Annotation( "UniProtKB:P16872") "CD127 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P16872") "IL-7 receptor subunit alpha (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P16872") "IL-7R subunit alpha (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P16872") "IL-7R-alpha (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P16872") "IL-7RA (mouse)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mIL7R") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P16872") Annotation( ) "Il7r") -AnnotationAssertion( "PR:P16872") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "interleukin-7 receptor subunit alpha (mouse)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (transcription factor PU.1 (mouse)) - -AnnotationAssertion(Annotation( "OMA:P17433") Annotation( "PRO:DNx") "A transcription factor PU.1 that is encoded in the genome of mouse.") -AnnotationAssertion( "UniProtKB:P17433") -AnnotationAssertion(Annotation( "UniProtKB:P17433") "31 kDa-transforming protein (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P17433") "SFFV proviral integration 1 protein (mouse)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mSPI1") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P17433") Annotation( ) "Sfpi-1") -AnnotationAssertion(Annotation( "UniProtKB:P17433") Annotation( ) "Sfpi1") -AnnotationAssertion(Annotation( "UniProtKB:P17433") Annotation( ) "Spi1") -AnnotationAssertion( "PR:P17433") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "transcription factor PU.1 (mouse)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (T-cell acute lymphocytic leukemia protein 1 (human)) - -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( "UniProtKB:P17542") "A T-cell acute lymphocytic leukemia protein 1 that is encoded in the genome of human.") -AnnotationAssertion(Annotation(rdfs:label "PR:P17542 located_in GO:0005654") "Reactome:R-HSA-8956511") -AnnotationAssertion( "UniProtKB:P17542") -AnnotationAssertion(Annotation( "UniProtKB:P17542") "Stem cell protein (human)") -AnnotationAssertion(Annotation( "UniProtKB:P17542") "T-cell leukemia/lymphoma protein 5 (human)") -AnnotationAssertion(Annotation( "UniProtKB:P17542") "TAL-1 (human)") -AnnotationAssertion(Annotation( "UniProtKB:P17542") "class A basic helix-loop-helix protein 17 (human)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hTAL1") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P17542") Annotation( ) "BHLHA17") -AnnotationAssertion(Annotation( "UniProtKB:P17542") Annotation( ) "SCL") -AnnotationAssertion(Annotation( "UniProtKB:P17542") Annotation( ) "TAL1") -AnnotationAssertion(Annotation( "UniProtKB:P17542") Annotation( ) "TCL5") -AnnotationAssertion( "PR:P17542") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "T-cell acute lymphocytic leukemia protein 1 (human)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (erythroid transcription factor (chicken)) - -AnnotationAssertion(Annotation( "PANTHER:PTHR10071:SF26") Annotation( "PRO:DNx") "An erythroid transcription factor that is encoded in the genome of chicken.") -AnnotationAssertion( "UniProtKB:P17678") -AnnotationAssertion(Annotation( "UniProtKB:P17678") "Eryf1 (chicken)") -AnnotationAssertion(Annotation( "UniProtKB:P17678") "GATA-1 (chicken)") -AnnotationAssertion(Annotation( "UniProtKB:P17678") "GATA-binding factor 1 (chicken)") -AnnotationAssertion(Annotation( "UniProtKB:P17678") "NF-E1 DNA-binding protein (chicken)") -AnnotationAssertion(Annotation( "UniProtKB:P17678") "NF-E1a (chicken)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "chick-GATA1") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P17678") Annotation( ) "ERYF1") -AnnotationAssertion(Annotation( "UniProtKB:P17678") Annotation( ) "GATA1") -AnnotationAssertion( "PR:P17678") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "erythroid transcription factor (chicken)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (erythroid transcription factor (mouse)) - -AnnotationAssertion(Annotation( "OMA:P17679") Annotation( "PRO:DNx") "An erythroid transcription factor that is encoded in the genome of mouse.") -AnnotationAssertion( "UniProtKB:P17679") -AnnotationAssertion(Annotation( "UniProtKB:P17679") "Eryf1 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P17679") "GATA-1 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P17679") "GATA-binding factor 1 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P17679") "GF-1 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P17679") "NF-E1 DNA-binding protein (mouse)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mGATA1") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P17679") Annotation( ) "Gata1") -AnnotationAssertion(Annotation( "UniProtKB:P17679") Annotation( ) "Gf-1") -AnnotationAssertion( "PR:P17679") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "erythroid transcription factor (mouse)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (endoglin (human)) - -AnnotationAssertion(Annotation( "PRO:CNA") Annotation( "UniProtKB:P17813") "An endoglin that is encoded in the genome of human.") -AnnotationAssertion( "UniProtKB:P17813") -AnnotationAssertion(Annotation( "UniProtKB:P17813") "CD105 (human)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hENG") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P17813") Annotation( ) "END") -AnnotationAssertion(Annotation( "UniProtKB:P17813") Annotation( ) "ENG") -AnnotationAssertion( "PR:P17813") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "endoglin (human)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (transcription factor PU.1 (human)) - -AnnotationAssertion(Annotation( "PRO:WCB") Annotation( "UniProtKB:P17947") "A transcription factor PU.1 that is encoded in the genome of human.") -AnnotationAssertion(Annotation(rdfs:label "PR:P17947 located_in GO:0005654") "Reactome:R-HSA-8865503") -AnnotationAssertion( "UniProtKB:P17947") -AnnotationAssertion(Annotation( "UniProtKB:P17947") "31 kDa-transforming protein (human)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hSPI1") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P17947") Annotation( ) "SPI1") -AnnotationAssertion( "PR:P17947") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "transcription factor PU.1 (human)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (CD48 antigen (mouse)) - -AnnotationAssertion(Annotation( "OMA:P18181") Annotation( "PRO:DNx") "A CD48 molecule that is encoded in the genome of mouse.") -AnnotationAssertion( "UniProtKB:P18181") -AnnotationAssertion(Annotation( "UniProtKB:P18181") "BCM1 surface antigen (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P18181") "BLAST-1 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P18181") "CD48 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P18181") "HM48-1 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P18181") "MRC OX-45 surface antigen (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P18181") "SLAM family member 2 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P18181") "SLAMF2 (mouse)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mCD48") -AnnotationAssertion(Annotation( "UniProtKB:P18181") "sgp-60 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P18181") "signaling lymphocytic activation molecule 2 (mouse)") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P18181") Annotation( ) "Bcm-1") -AnnotationAssertion(Annotation( "UniProtKB:P18181") Annotation( ) "Cd48") -AnnotationAssertion( "PR:P18181") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "CD48 antigen (mouse)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (syndecan-1 (human)) - -AnnotationAssertion(Annotation( "PRO:WCB") Annotation( "UniProtKB:P18827") "A syndecan-1 that is encoded in the genome of human.") -AnnotationAssertion( "UniProtKB:P18827") -AnnotationAssertion(Annotation( "UniProtKB:P18827") "CD138 (human)") -AnnotationAssertion(Annotation( "UniProtKB:P18827") "SYND1 (human)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hSDC1") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P18827") Annotation( ) "SDC") -AnnotationAssertion(Annotation( "UniProtKB:P18827") Annotation( ) "SDC1") -AnnotationAssertion( "PR:P18827") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "syndecan-1 (human)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (syndecan-1 (mouse)) - -AnnotationAssertion(Annotation( "OMA:P18828") Annotation( "PRO:DNx") "A syndecan-1 that is encoded in the genome of mouse.") -AnnotationAssertion( "UniProtKB:P18828") -AnnotationAssertion(Annotation( "UniProtKB:P18828") "CD138 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P18828") "SYND1 (mouse)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mSDC1") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P18828") Annotation( ) "Sdc1") -AnnotationAssertion(Annotation( "UniProtKB:P18828") Annotation( ) "Synd-1") -AnnotationAssertion(Annotation( "UniProtKB:P18828") Annotation( ) "Synd1") -AnnotationAssertion( "PR:P18828") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "syndecan-1 (mouse)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (complement receptor type 2 (mouse)) - -AnnotationAssertion(Annotation( "PRO:WCB") "A complement receptor type 2 that is encoded in the genome of mouse.") -AnnotationAssertion( "UniProtKB:P19070") -AnnotationAssertion(Annotation( "UniProtKB:P19070") "CD21 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P19070") "complement C3d receptor (mouse)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mCR2") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P19070") Annotation( ) "Cr2") -AnnotationAssertion( "PR:P19070") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "complement receptor type 2 (mouse)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (B-lymphocyte antigen CD20 (mouse)) - -AnnotationAssertion(Annotation( "OMA:P19437") Annotation( "PRO:DNx") "A membrane-spanning 4-domains subfamily A member 1 that is encoded in the genome of mouse.") -AnnotationAssertion( "UniProtKB:P19437") -AnnotationAssertion(Annotation( "UniProtKB:P19437") "B-cell differentiation antigen Ly-44 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P19437") "CD20 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P19437") "lymphocyte antigen 44 (mouse)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mMS4A1") -AnnotationAssertion(Annotation( "UniProtKB:P19437") "membrane-spanning 4-domains subfamily A member 1 (mouse)") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P19437") Annotation( ) "Cd20") -AnnotationAssertion(Annotation( "UniProtKB:P19437") Annotation( ) "Ly-44") -AnnotationAssertion(Annotation( "UniProtKB:P19437") Annotation( ) "Ms4a1") -AnnotationAssertion(Annotation( "UniProtKB:P19437") Annotation( ) "Ms4a2") -AnnotationAssertion( "PR:P19437") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "B-lymphocyte antigen CD20 (mouse)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (complement receptor type 2 (human)) - -AnnotationAssertion(Annotation( "PRO:WCB") Annotation( "UniProtKB:P20023") "A complement receptor type 2 that is encoded in the genome of human.") -AnnotationAssertion( "UniProtKB:P20023") -AnnotationAssertion(Annotation( "UniProtKB:P20023") "CD21 (human)") -AnnotationAssertion(Annotation( "UniProtKB:P20023") "Cr2 (human)") -AnnotationAssertion(Annotation( "UniProtKB:P20023") "EBV receptor (human)") -AnnotationAssertion(Annotation( "UniProtKB:P20023") "complement C3d receptor (human)") -AnnotationAssertion(Annotation( "UniProtKB:P20023") "epstein-Barr virus receptor (human)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hCR2") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P20023") Annotation( ) "C3DR") -AnnotationAssertion(Annotation( "UniProtKB:P20023") Annotation( ) "CR2") -AnnotationAssertion( "PR:P20023") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "complement receptor type 2 (human)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (myeloid cell surface antigen CD33 (human)) - -AnnotationAssertion(Annotation( "PRO:WCB") Annotation( "UniProtKB:P20138") "A CD33 molecule that is encoded in the genome of human.") -AnnotationAssertion( "UniProtKB:P20138") -AnnotationAssertion(Annotation( "UniProtKB:P20138") "gp67 (human)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hCD33") -AnnotationAssertion(Annotation( "UniProtKB:P20138") "sialic acid-binding Ig-like lectin 3 (human)") -AnnotationAssertion(Annotation( "UniProtKB:P20138") "siglec-3 (human)") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P20138") Annotation( ) "CD33") -AnnotationAssertion(Annotation( "UniProtKB:P20138") Annotation( ) "SIGLEC3") -AnnotationAssertion( "PR:P20138") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "myeloid cell surface antigen CD33 (human)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (low affinity immunoglobulin epsilon Fc receptor (mouse)) - -AnnotationAssertion(Annotation( "OMA:P20693") Annotation( "PRO:DNx") "A low affinity immunoglobulin epsilon Fc receptor that is encoded in the genome of mouse.") -AnnotationAssertion( "UniProtKB:P20693") -AnnotationAssertion(Annotation( "UniProtKB:P20693") "CD23 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P20693") "Fc-epsilon-RII (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P20693") "lymphocyte IgE receptor (mouse)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mFCER2") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P20693") Annotation( ) "Fcer2") -AnnotationAssertion(Annotation( "UniProtKB:P20693") Annotation( ) "Fcer2a") -AnnotationAssertion( "PR:P20693") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "low affinity immunoglobulin epsilon Fc receptor (mouse)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (integrin alpha-X (human)) - -AnnotationAssertion( "An integrin alpha-X that is encoded in the genome of human.") -AnnotationAssertion( "UniProtKB:P20702") -AnnotationAssertion(Annotation( "UniProtKB:P20702") "CD11 antigen-like family member C (human)") -AnnotationAssertion(Annotation( "UniProtKB:P20702") "Leu M5 (human)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hITGAX") -AnnotationAssertion(Annotation( "UniProtKB:P20702") "leukocyte adhesion glycoprotein p150,95 alpha chain (human)") -AnnotationAssertion(Annotation( "UniProtKB:P20702") "leukocyte adhesion receptor p150,95 (human)") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P20702") Annotation( ) "CD11C") -AnnotationAssertion(Annotation( "UniProtKB:P20702") Annotation( ) "ITGAX") -AnnotationAssertion( "PR:P20702") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "integrin alpha-X (human)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (interleukin-5 receptor subunit alpha (mouse)) - -AnnotationAssertion(Annotation( "OMA:P21183") Annotation( "PRO:DNx") "An interleukin-5 receptor subunit alpha that is encoded in the genome of mouse.") -AnnotationAssertion( "UniProtKB:P21183") -AnnotationAssertion(Annotation( "UniProtKB:P21183") "CD125 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P21183") "IL-5 receptor subunit alpha (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P21183") "IL-5R subunit alpha (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P21183") "IL-5R-alpha (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P21183") "IL-5RA (mouse)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mIL5RA") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P21183") Annotation( ) "Il5r") -AnnotationAssertion(Annotation( "UniProtKB:P21183") Annotation( ) "Il5ra") -AnnotationAssertion( "PR:P21183") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "interleukin-5 receptor subunit alpha (mouse)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (V(D)J recombination-activating protein 2 (mouse)) - -AnnotationAssertion(Annotation( "OMA:P21784") Annotation( "PRO:DNx") "A V(D)J recombination-activating protein 2 that is encoded in the genome of mouse.") -AnnotationAssertion( "UniProtKB:P21784") -AnnotationAssertion(Annotation( "UniProtKB:P21784") "RAG-2 (mouse)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mRAG2") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P21784") Annotation( ) "Rag-2") -AnnotationAssertion(Annotation( "UniProtKB:P21784") Annotation( ) "Rag2") -AnnotationAssertion( "PR:P21784") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "V(D)J recombination-activating protein 2 (mouse)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (T-cell acute lymphocytic leukemia protein 1 homolog (mouse)) - -AnnotationAssertion(Annotation( "OMA:P22091") Annotation( "PRO:DNx") "A T-cell acute lymphocytic leukemia protein 1 that is encoded in the genome of mouse.") -AnnotationAssertion( "UniProtKB:P22091") -AnnotationAssertion(Annotation( "UniProtKB:P22091") "Stem cell protein (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P22091") "TAL-1 (mouse)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mTAL1") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P22091") Annotation( ) "Scl") -AnnotationAssertion(Annotation( "UniProtKB:P22091") Annotation( ) "Tal-1") -AnnotationAssertion(Annotation( "UniProtKB:P22091") Annotation( ) "Tal1") -AnnotationAssertion( "PR:P22091") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "T-cell acute lymphocytic leukemia protein 1 homolog (mouse)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (T-cell surface glycoprotein CD3 epsilon chain (mouse)) - -AnnotationAssertion(Annotation( "OMA:P22646") Annotation( "PRO:DNx") "A CD3 epsilon that is encoded in the genome of mouse.") -AnnotationAssertion( "UniProtKB:P22646") -AnnotationAssertion(Annotation( "UniProtKB:P22646") "CD3e (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P22646") "T-cell surface antigen T3/Leu-4 epsilon chain (mouse)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mCD3E") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P22646") Annotation( ) "Cd3e") -AnnotationAssertion( "PR:P22646") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "T-cell surface glycoprotein CD3 epsilon chain (mouse)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (endothelial transcription factor GATA-2 (human)) - -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( "UniProtKB:P23769") "An endothelial transcription factor GATA-2 that is encoded in the genome of human.") -AnnotationAssertion(Annotation(rdfs:label "PR:P23769 located_in GO:0005654") "Reactome:R-HSA-996735") -AnnotationAssertion( "UniProtKB:P23769") -AnnotationAssertion(Annotation( "UniProtKB:P23769") "GATA-binding protein 2 (human)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hGATA2") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P23769") Annotation( ) "GATA2") -AnnotationAssertion( "PR:P23769") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "endothelial transcription factor GATA-2 (human)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (GATA-binding factor 2 (chicken)) - -AnnotationAssertion(Annotation( "OMA:P23824") Annotation( "PANTHER:PTHR10071:SF107") Annotation( "PRO:DNx") "An endothelial transcription factor GATA-2 that is encoded in the genome of chicken.") -AnnotationAssertion( "UniProtKB:P23824") -AnnotationAssertion(Annotation( "UniProtKB:P23824") "GATA-2 (chicken)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "chick-GATA2") -AnnotationAssertion(Annotation( "UniProtKB:P23824") "transcription factor NF-E1b (chicken)") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P23824") Annotation( ) "GATA2") -AnnotationAssertion( "PR:P23824") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "GATA-binding factor 2 (chicken)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (V(D)J recombination-activating protein 1 (chicken)) - -AnnotationAssertion(Annotation( "OMA:P24271") Annotation( "PRO:DNx") "A V(D)J recombination-activating protein 1 that is encoded in the genome of chicken.") -AnnotationAssertion( "UniProtKB:P24271") -AnnotationAssertion(Annotation( "UniProtKB:P24271") "RAG-1 (chicken)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "chick-RAG1") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P24271") Annotation( ) "RAG1") -AnnotationAssertion( "PR:P24271") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "V(D)J recombination-activating protein 1 (chicken)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (signal transducer CD24 (mouse)) - -AnnotationAssertion(Annotation( "OMA:P24807") Annotation( "PRO:WCB") "A signal transducer CD24 that is encoded in the genome of mouse.") -AnnotationAssertion( "UniProtKB:P24807") -AnnotationAssertion(Annotation( "UniProtKB:P24807") "CD24 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P24807") "HSA (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P24807") "M1/69-J11D heat stable antigen (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P24807") "R13-Ag (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P24807") "X62 heat stable antigen (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P24807") "lymphocyte antigen 52 (mouse)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mCD24") -AnnotationAssertion(Annotation( "UniProtKB:P24807") "nectadrin (mouse)") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P24807") Annotation( ) "Cd24") -AnnotationAssertion(Annotation( "UniProtKB:P24807") Annotation( ) "Cd24a") -AnnotationAssertion(Annotation( "UniProtKB:P24807") Annotation( ) "Ly-52") -AnnotationAssertion( "PR:P24807") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "signal transducer CD24 (mouse)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (T-cell acute lymphocytic leukemia protein 1 homolog (chicken)) - -AnnotationAssertion(Annotation( "OMA:P24899") Annotation( "PRO:DNx") "A T-cell acute lymphocytic leukemia protein 1 that is encoded in the genome of chicken.") -AnnotationAssertion( "UniProtKB:P24899") -AnnotationAssertion(Annotation( "UniProtKB:P24899") "Stem cell protein (chicken)") -AnnotationAssertion(Annotation( "UniProtKB:P24899") "TAL-1 (chicken)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "chick-TAL1") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P24899") Annotation( ) "SCL") -AnnotationAssertion(Annotation( "UniProtKB:P24899") Annotation( ) "TAL1") -AnnotationAssertion( "PR:P24899") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "T-cell acute lymphocytic leukemia protein 1 homolog (chicken)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (signal transducer CD24 (human)) - -AnnotationAssertion(Annotation( "PRO:WCB") Annotation( "UniProtKB:P25063") "A signal transducer CD24 that is encoded in the genome of human.") -AnnotationAssertion( "UniProtKB:P25063") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hCD24") -AnnotationAssertion(Annotation( "UniProtKB:P25063") "small cell lung carcinoma cluster 4 antigen (human)") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P25063") Annotation( ) "CD24") -AnnotationAssertion(Annotation( "UniProtKB:P25063") Annotation( ) "CD24A") -AnnotationAssertion( "PR:P25063") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "signal transducer CD24 (human)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (B-lymphocyte antigen CD19 (mouse)) - -AnnotationAssertion(Annotation( "OMA:P25918") Annotation( "PRO:DNx") "A CD19 molecule that is encoded in the genome of mouse.") -AnnotationAssertion( "UniProtKB:P25918") -AnnotationAssertion(Annotation( "UniProtKB:P25918") "CD19 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P25918") "differentiation antigen CD19 (mouse)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mCD19") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P25918") Annotation( ) "Cd19") -AnnotationAssertion( "PR:P25918") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "B-lymphocyte antigen CD19 (mouse)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (CD27 antigen (human)) - -AnnotationAssertion(Annotation( "PRO:WCB") Annotation( "UniProtKB:P26842") "A CD27 molecule that is encoded in the genome of human.") -AnnotationAssertion( "UniProtKB:P26842") -AnnotationAssertion(Annotation( "UniProtKB:P26842") "CD27L receptor (human)") -AnnotationAssertion(Annotation( "UniProtKB:P26842") "T-cell activation antigen CD27 (human)") -AnnotationAssertion(Annotation( "UniProtKB:P26842") "T14 (human)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hCD27") -AnnotationAssertion(Annotation( "UniProtKB:P26842") "tumor necrosis factor receptor superfamily member 7 (human)") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P26842") Annotation( ) "CD27") -AnnotationAssertion(Annotation( "UniProtKB:P26842") Annotation( ) "TNFRSF7") -AnnotationAssertion( "PR:P26842") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "CD27 antigen (human)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (interleukin-3 receptor subunit alpha (human)) - -AnnotationAssertion(Annotation( "PRO:WCB") Annotation( "UniProtKB:P26951") "An interleukin-3 receptor class 2 alpha chain that is encoded in the genome of human.") -AnnotationAssertion( "UniProtKB:P26951") -AnnotationAssertion(Annotation( "UniProtKB:P26951") "CD123 (human)") -AnnotationAssertion(Annotation( "UniProtKB:P26951") "IL-3 receptor subunit alpha (human)") -AnnotationAssertion(Annotation( "UniProtKB:P26951") "IL-3R subunit alpha (human)") -AnnotationAssertion(Annotation( "UniProtKB:P26951") "IL-3R-alpha (human)") -AnnotationAssertion(Annotation( "UniProtKB:P26951") "IL-3RA (human)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hIL3RA") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P26951") Annotation( ) "IL3R") -AnnotationAssertion(Annotation( "UniProtKB:P26951") Annotation( ) "IL3RA") -AnnotationAssertion( "PR:P26951") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "interleukin-3 receptor subunit alpha (human)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (interleukin-3 receptor subunit alpha (mouse)) - -AnnotationAssertion(Annotation( "OMA:P26952") Annotation( "PRO:DNx") "An interleukin-3 receptor class 2 alpha chain that is encoded in the genome of mouse.") -AnnotationAssertion( "UniProtKB:P26952") -AnnotationAssertion(Annotation( "UniProtKB:P26952") "CD123 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P26952") "IL-3 receptor subunit alpha (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P26952") "IL-3R subunit alpha (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P26952") "IL-3R-alpha (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P26952") "IL-3RA (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P26952") "interleukin-3 receptor class II alpha chain (mouse)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mIL3RA") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P26952") Annotation( ) "Il3ra") -AnnotationAssertion(Annotation( "UniProtKB:P26952") Annotation( ) "Sut-1") -AnnotationAssertion( "PR:P26952") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "interleukin-3 receptor subunit alpha (mouse)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (killer cell lectin-like receptor subfamily B member 1C (mouse)) - -AnnotationAssertion(Annotation( "PRO:CNA") Annotation( "UniProtKB:P27814") "A killer cell lectin-like receptor subfamily B member 1C that is encoded in the genome of mouse.") -AnnotationAssertion( "UniProtKB:P27814") -AnnotationAssertion(Annotation( "UniProtKB:P27814") "CD161 antigen-like family member C (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P27814") "CD161c (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P27814") "Ly-55c (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P27814") "NK1.1 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P27814") "NKR-P1 40 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P27814") "NKR-P1.9 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P27814") "NKR-P1C (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P27814") "lymphocyte antigen 55c (mouse)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mKlrb1c") -AnnotationAssertion(Annotation( "UniProtKB:P27814") "natural killer cell surface protein P1-40 (mouse)") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P27814") Annotation( ) "Klrb1c") -AnnotationAssertion(Annotation( "UniProtKB:P27814") Annotation( ) "Ly55c") -AnnotationAssertion(Annotation( "UniProtKB:P27814") Annotation( ) "Nkrp1c") -AnnotationAssertion( "PR:P27814") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "killer cell lectin-like receptor subfamily B member 1C (mouse)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (hematopoietic progenitor cell antigen CD34 (human)) - -AnnotationAssertion( "A CD34 molecule that is encoded in the genome of human.") -AnnotationAssertion( "UniProtKB:P28906") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hCD34") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P28906") Annotation( ) "CD34") -AnnotationAssertion( "PR:P28906") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "hematopoietic progenitor cell antigen CD34 (human)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 (human)) - -AnnotationAssertion(Annotation( "PRO:WCB") Annotation( "UniProtKB:P28907") "An ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 that is encoded in the genome of human.") -AnnotationAssertion(Annotation(rdfs:label "PR:P28907 located_in GO:0005886") "Reactome:R-HSA-8938080") -AnnotationAssertion( "UniProtKB:P28907") -AnnotationAssertion(Annotation( "UniProtKB:P28907") "2'-phospho-ADP-ribosyl cyclase (human)") -AnnotationAssertion(Annotation( "UniProtKB:P28907") "2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase (human)") -AnnotationAssertion(Annotation( "UniProtKB:P28907") "2'-phospho-cyclic-ADP-ribose transferase (human)") -AnnotationAssertion( "ADP-ribosyl cyclase 1 (human)") -AnnotationAssertion(Annotation( "UniProtKB:P28907") "ADPRC 1 (human)") -AnnotationAssertion(Annotation( "UniProtKB:P28907") "T10 (human)") -AnnotationAssertion(Annotation( "UniProtKB:P28907") "cADPr hydrolase 1 (human)") -AnnotationAssertion(Annotation( "UniProtKB:P28907") "cyclic ADP-ribose hydrolase 1 (human)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hCD38") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P28907") Annotation( ) "CD38") -AnnotationAssertion( "PR:P28907") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 (human)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (low affinity immunoglobulin gamma Fc region receptor II-b (human)) - -AnnotationAssertion(Annotation( "PRO:CNA") Annotation( "UniProtKB:P31994") "A low affinity immunoglobulin gamma Fc region receptor II-b that is encoded in the genome of human.") -AnnotationAssertion(Annotation( "UniProtKB:P31994") "CD32 (human)") -AnnotationAssertion(Annotation( "UniProtKB:P31994") "CDw32 (human)") -AnnotationAssertion( "UniProtKB:P31994") -AnnotationAssertion(Annotation( "UniProtKB:P31994") "Fc-gamma RII-b (human)") -AnnotationAssertion(Annotation( "UniProtKB:P31994") "Fc-gamma-RIIb (human)") -AnnotationAssertion(Annotation( "UniProtKB:P31994") "FcRII-b (human)") -AnnotationAssertion(Annotation( "UniProtKB:P31994") "IgG Fc receptor II-b (human)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hFCGR2B") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P31994") Annotation( ) "CD32") -AnnotationAssertion(Annotation( "UniProtKB:P31994") Annotation( ) "FCG2") -AnnotationAssertion(Annotation( "UniProtKB:P31994") Annotation( ) "FCGR2B") -AnnotationAssertion(Annotation( "UniProtKB:P31994") Annotation( ) "IGFR2") -AnnotationAssertion( "PR:P31994") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "low affinity immunoglobulin gamma Fc region receptor II-b (human)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (carcinoembryonic antigen-related cell adhesion molecule 8 (human)) - -AnnotationAssertion(Annotation( "PRO:CNA") Annotation( "UniProtKB:P31997") "A carcinoembryonic antigen-related cell adhesion molecule 8 that is encoded in the genome of human.") -AnnotationAssertion( "UniProtKB:P31997") -AnnotationAssertion(Annotation( "UniProtKB:P31997") "CD66b (human)") -AnnotationAssertion(Annotation( "UniProtKB:P31997") "CD67 antigen (human)") -AnnotationAssertion(Annotation( "UniProtKB:P31997") "carcinoembryonic antigen CGM6 (human)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hCEACAM8") -AnnotationAssertion(Annotation( "UniProtKB:P31997") "non-specific cross-reacting antigen NCA-95 (human)") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P31997") Annotation( ) "CEACAM8") -AnnotationAssertion(Annotation( "UniProtKB:P31997") Annotation( ) "CGM6") -AnnotationAssertion( "PR:P31997") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "carcinoembryonic antigen-related cell adhesion molecule 8 (human)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cadherin-5 (human)) - -AnnotationAssertion(Annotation( "PRO:WCB") Annotation( "UniProtKB:P33151") "A cadherin-5 that is encoded in the genome of human.") -AnnotationAssertion( "UniProtKB:P33151") -AnnotationAssertion(Annotation( "UniProtKB:P33151") "7B4 antigen (human)") -AnnotationAssertion(Annotation( "UniProtKB:P33151") "CD144 (human)") -AnnotationAssertion(Annotation( "UniProtKB:P33151") "VE-cadherin (human)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hCDH5") -AnnotationAssertion(Annotation( "UniProtKB:P33151") "vascular endothelial cadherin (human)") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P33151") Annotation( ) "CDH5") -AnnotationAssertion( "PR:P33151") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "cadherin-5 (human)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (urokinase plasminogen activator surface receptor (mouse)) - -AnnotationAssertion(Annotation( "OMA:P35456") Annotation( "PRO:DNx") "A urokinase plasminogen activator surface receptor that is encoded in the genome of mouse.") -AnnotationAssertion( "UniProtKB:P35456") -AnnotationAssertion(Annotation( "UniProtKB:P35456") "CD87 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P35456") "U-PAR (mouse)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mPLAUR") -AnnotationAssertion(Annotation( "UniProtKB:P35456") "uPAR (mouse)") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P35456") Annotation( ) "Plaur") -AnnotationAssertion( "PR:P35456") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "urokinase plasminogen activator surface receptor (mouse)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (lymphocyte antigen 6G (mouse)) - -AnnotationAssertion(Annotation( "PRO:CNA") Annotation( "UniProtKB:P35461") "A lymphocyte antigen 6G that is encoded in the genome of mouse.") -AnnotationAssertion( "UniProtKB:P35461") -AnnotationAssertion(Annotation( "UniProtKB:P35461") "Ly-6G (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P35461") "Ly-6G.1 (mouse)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mLy6g") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P35461") Annotation( ) "Ly6g") -AnnotationAssertion( "PR:P35461") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "lymphocyte antigen 6G (mouse)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (vascular endothelial growth factor receptor 2 (mouse)) - -AnnotationAssertion(Annotation( "OMA:P35918") Annotation( "PRO:DNx") "A vascular endothelial growth factor receptor 2 that is encoded in the genome of mouse.") -AnnotationAssertion( "UniProtKB:P35918") -AnnotationAssertion(Annotation( "UniProtKB:P35918") "CD309 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P35918") "FLK-1 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P35918") "VEGFR-2 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P35918") "fetal liver kinase 1 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P35918") "kinase NYK (mouse)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mKDR") -AnnotationAssertion(Annotation( "UniProtKB:P35918") "protein-tyrosine kinase receptor flk-1 (mouse)") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P35918") Annotation( ) "Flk-1") -AnnotationAssertion(Annotation( "UniProtKB:P35918") Annotation( ) "Flk1") -AnnotationAssertion(Annotation( "UniProtKB:P35918") Annotation( ) "Kdr") -AnnotationAssertion( "PR:P35918") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "vascular endothelial growth factor receptor 2 (mouse)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (vascular endothelial growth factor receptor 2 (human)) - -AnnotationAssertion(Annotation( "PRO:WCB") Annotation( "UniProtKB:P35968") "A vascular endothelial growth factor receptor 2 that is encoded in the genome of human.") -AnnotationAssertion( "DTO:03100560") -AnnotationAssertion( "UniProtKB:P35968") -AnnotationAssertion(Annotation( "UniProtKB:P35968") "CD309 (human)") -AnnotationAssertion(Annotation( "UniProtKB:P35968") "FLK-1 (human)") -AnnotationAssertion(Annotation( "UniProtKB:P35968") "VEGFR-2 (human)") -AnnotationAssertion(Annotation( "UniProtKB:P35968") "fetal liver kinase 1 (human)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hKDR") -AnnotationAssertion(Annotation( "UniProtKB:P35968") "kinase insert domain receptor (human)") -AnnotationAssertion(Annotation( "UniProtKB:P35968") "protein-tyrosine kinase receptor flk-1 (human)") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P35968") Annotation( ) "FLK1") -AnnotationAssertion(Annotation( "UniProtKB:P35968") Annotation( ) "KDR") -AnnotationAssertion(Annotation( "UniProtKB:P35968") Annotation( ) "VEGFR2") -AnnotationAssertion( "PR:P35968") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "vascular endothelial growth factor receptor 2 (human)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (DNA nucleotidylexotransferase (chicken)) - -AnnotationAssertion(Annotation( "PRO:DNx") "A DNA nucleotidylexotransferase that is encoded in the genome of chicken.") -AnnotationAssertion( "UniProtKB:P36195") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "chick-DNTT") -AnnotationAssertion(Annotation( "UniProtKB:P36195") "terminal addition enzyme (chicken)") -AnnotationAssertion(Annotation( "UniProtKB:P36195") "terminal deoxynucleotidyltransferase (chicken)") -AnnotationAssertion(Annotation( "UniProtKB:P36195") "terminal transferase (chicken)") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P36195") Annotation( ) "DNTT") -AnnotationAssertion(Annotation( "UniProtKB:P36195") Annotation( ) "TDT") -AnnotationAssertion( "PR:P36195") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "DNA nucleotidylexotransferase (chicken)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (receptor-type tyrosine-protein kinase FLT3 (human)) - -AnnotationAssertion(Annotation( "PRO:WCB") Annotation( "UniProtKB:P36888") "A receptor-type tyrosine-protein kinase FLT3 that is encoded in the genome of human.") -AnnotationAssertion(Annotation( "UniProtKB:P36888") "STK-1 (human)") -AnnotationAssertion( "DTO:03100154") -AnnotationAssertion( "UniProtKB:P36888") -AnnotationAssertion(Annotation( "UniProtKB:P36888") "FL cytokine receptor (human)") -AnnotationAssertion(Annotation( "UniProtKB:P36888") "FLK-2 (human)") -AnnotationAssertion(Annotation( "UniProtKB:P36888") "FLT-3 (human)") -AnnotationAssertion(Annotation( "UniProtKB:P36888") "Stem cell tyrosine kinase 1 (human)") -AnnotationAssertion(Annotation( "UniProtKB:P36888") "fetal liver kinase-2 (human)") -AnnotationAssertion(Annotation( "UniProtKB:P36888") "fms-like tyrosine kinase 3 (human)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hFLT3") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P36888") Annotation( ) "CD135") -AnnotationAssertion(Annotation( "UniProtKB:P36888") Annotation( ) "FLK2") -AnnotationAssertion(Annotation( "UniProtKB:P36888") Annotation( ) "FLT3") -AnnotationAssertion(Annotation( "UniProtKB:P36888") Annotation( ) "STK1") -AnnotationAssertion( "PR:P36888") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "receptor-type tyrosine-protein kinase FLT3 (human)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (fibroblast growth factor 8 (mouse)) - -AnnotationAssertion(Annotation( "OMA:P37237") Annotation( "PRO:DNx") "A fibroblast growth factor 8 that is encoded in the genome of mouse.") -AnnotationAssertion( "UniProtKB:P37237") -AnnotationAssertion(Annotation( "UniProtKB:P37237") "AIGF (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P37237") "FGF-8 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P37237") "androgen-induced growth factor (mouse)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mFGF8") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P37237") Annotation( ) "Aigf") -AnnotationAssertion(Annotation( "UniProtKB:P37237") Annotation( ) "Fgf8") -AnnotationAssertion(Annotation( "UniProtKB:P37237") "HBGF-8 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P37237") "heparin-binding growth factor 8 (mouse)") -AnnotationAssertion( "PR:P37237") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "fibroblast growth factor 8 (mouse)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (CD27 antigen (mouse)) - -AnnotationAssertion(Annotation( "OMA:P41272") Annotation( "PRO:DNx") "A CD27 molecule that is encoded in the genome of mouse.") -AnnotationAssertion( "UniProtKB:P41272") -AnnotationAssertion(Annotation( "UniProtKB:P41272") "CD27 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P41272") "CD27L receptor (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P41272") "T-cell activation antigen CD27 (mouse)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mCD27") -AnnotationAssertion(Annotation( "UniProtKB:P41272") "tumor necrosis factor receptor superfamily member 7 (mouse)") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P41272") Annotation( ) "Cd27") -AnnotationAssertion(Annotation( "UniProtKB:P41272") Annotation( ) "Tnfrsf7") -AnnotationAssertion( "PR:P41272") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "CD27 antigen (mouse)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (C-C chemokine receptor type 2 (human)) - -AnnotationAssertion(Annotation( "PRO:WCB") Annotation( "UniProtKB:P41597") "A C-C chemokine receptor type 2 that is encoded in the genome of human.") -AnnotationAssertion( "DTO:02100054") -AnnotationAssertion(Annotation(rdfs:label "PR:P41597 located_in GO:0005886") "Reactome:R-HSA-2976755") -AnnotationAssertion( "UniProtKB:P41597") -AnnotationAssertion(Annotation( "UniProtKB:P41597") "C-C CKR-2 (human)") -AnnotationAssertion(Annotation( "UniProtKB:P41597") "CC-CKR-2 (human)") -AnnotationAssertion(Annotation( "UniProtKB:P41597") "CCR-2 (human)") -AnnotationAssertion(Annotation( "UniProtKB:P41597") "CD192 (human)") -AnnotationAssertion(Annotation( "UniProtKB:P41597") "MCP-1-R (human)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hCCR2") -AnnotationAssertion(Annotation( "UniProtKB:P41597") "monocyte chemoattractant protein 1 receptor (human)") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P41597") Annotation( ) "CCR2") -AnnotationAssertion(Annotation( "UniProtKB:P41597") Annotation( ) "CMKBR2") -AnnotationAssertion( "PR:P41597") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "C-C chemokine receptor type 2 (human)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cathepsin K (human)) - -AnnotationAssertion(Annotation( "PRO:WCB") Annotation( "UniProtKB:P43235") "A cathepsin K that is encoded in the genome of human.") -AnnotationAssertion(Annotation( "UniProtKB:P43235") "cathepsin X (human)") -AnnotationAssertion( "UniProtKB:P43235") -AnnotationAssertion(Annotation( "UniProtKB:P43235") "cathepsin O2 (human)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hCTSK") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P43235") Annotation( ) "CTSK") -AnnotationAssertion(Annotation( "UniProtKB:P43235") Annotation( ) "CTSO") -AnnotationAssertion(Annotation( "UniProtKB:P43235") Annotation( ) "CTSO2") -AnnotationAssertion(Annotation( "UniProtKB:P43235") "cathepsin O (human)") -AnnotationAssertion( "PR:P43235") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "cathepsin K (human)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (CX3C chemokine receptor 1 (human)) - -AnnotationAssertion(Annotation( "PRO:WCB") Annotation( "UniProtKB:P49238") "A CX3C chemokine receptor 1 that is encoded in the genome of human.") -AnnotationAssertion( "DTO:02100074") -AnnotationAssertion(Annotation(rdfs:label "PR:P49238 located_in GO:0005886") "Reactome:R-HSA-2980688") -AnnotationAssertion( "UniProtKB:P49238") -AnnotationAssertion(Annotation( "UniProtKB:P49238") "C-X3-C CKR-1 (human)") -AnnotationAssertion(Annotation( "UniProtKB:P49238") "CMK-BRL-1 (human)") -AnnotationAssertion(Annotation( "UniProtKB:P49238") "CMK-BRL1 (human)") -AnnotationAssertion(Annotation( "UniProtKB:P49238") "G-protein coupled receptor 13 (human)") -AnnotationAssertion(Annotation( "UniProtKB:P49238") "V28 (human)") -AnnotationAssertion(Annotation( "UniProtKB:P49238") "beta chemokine receptor-like 1 (human)") -AnnotationAssertion(Annotation( "UniProtKB:P49238") "fractalkine receptor (human)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hCX3CR1") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P49238") Annotation( ) "CMKBRL1") -AnnotationAssertion(Annotation( "UniProtKB:P49238") Annotation( ) "CX3CR1") -AnnotationAssertion(Annotation( "UniProtKB:P49238") Annotation( ) "GPR13") -AnnotationAssertion( "PR:P49238") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "CX3C chemokine receptor 1 (human)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (CCAAT/enhancer-binding protein alpha (human)) - -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( "UniProtKB:P49715") "A CCAAT/enhancer-binding protein alpha that is encoded in the genome of human.") -AnnotationAssertion(Annotation(rdfs:label "PR:P49715 located_in GO:0005654") "Reactome:R-HSA-381289") -AnnotationAssertion( "UniProtKB:P49715") -AnnotationAssertion(Annotation( "UniProtKB:P49715") "C/EBP alpha (human)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hCEBPA") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P49715") Annotation( ) "CEBP") -AnnotationAssertion(Annotation( "UniProtKB:P49715") Annotation( ) "CEBPA") -AnnotationAssertion( "PR:P49715") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "CCAAT/enhancer-binding protein alpha (human)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (T-cell antigen CD7 (mouse)) - -AnnotationAssertion(Annotation( "OMA:P50283") Annotation( "PRO:DNx") "A CD7 molecule that is encoded in the genome of mouse.") -AnnotationAssertion( "UniProtKB:P50283") -AnnotationAssertion(Annotation( "UniProtKB:P50283") "CD7 (mouse)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mCD7") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P50283") Annotation( ) "Cd7") -AnnotationAssertion( "PR:P50283") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "T-cell antigen CD7 (mouse)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (C-C chemokine receptor type 2 (mouse)) - -AnnotationAssertion(Annotation( "OMA:P51683") Annotation( "PRO:DNx") "A C-C chemokine receptor type 2 that is encoded in the genome of mouse.") -AnnotationAssertion( "UniProtKB:P51683") -AnnotationAssertion(Annotation( "UniProtKB:P51683") "C-C CKR-2 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P51683") "CC-CKR-2 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P51683") "CCR-2 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P51683") "CCR2 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P51683") "CD192 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P51683") "JE/FIC receptor (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P51683") "MCP-1 receptor (mouse)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mCCR2") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P51683") Annotation( ) "Ccr2") -AnnotationAssertion(Annotation( "UniProtKB:P51683") Annotation( ) "Cmkbr2") -AnnotationAssertion( "PR:P51683") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "C-C chemokine receptor type 2 (mouse)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (CCAAT/enhancer-binding protein alpha (mouse)) - -AnnotationAssertion(Annotation( "OMA:P53566") Annotation( "PRO:DNx") "A CCAAT/enhancer-binding protein alpha that is encoded in the genome of mouse.") -AnnotationAssertion( "UniProtKB:P53566") -AnnotationAssertion(Annotation( "UniProtKB:P53566") "C/EBP alpha (mouse)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mCEBPA") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P53566") Annotation( ) "Cebp") -AnnotationAssertion(Annotation( "UniProtKB:P53566") Annotation( ) "Cebpa") -AnnotationAssertion( "PR:P53566") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "CCAAT/enhancer-binding protein alpha (mouse)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (fibroblast growth factor 8 (human)) - -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( "UniProtKB:P55075") "A fibroblast growth factor 8 that is encoded in the genome of human.") -AnnotationAssertion(Annotation( "UniProtKB:P55075") "HBGF-8 (human)") -AnnotationAssertion(Annotation( "UniProtKB:P55075") "heparin-binding growth factor 8 (human)") -AnnotationAssertion( "UniProtKB:P55075") -AnnotationAssertion(Annotation( "UniProtKB:P55075") "FGF-8 (human)") -AnnotationAssertion(Annotation( "UniProtKB:P55075") "androgen-induced growth factor (human)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hFGF8") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P55075") Annotation( ) "AIGF") -AnnotationAssertion(Annotation( "UniProtKB:P55075") Annotation( ) "FGF8") -AnnotationAssertion( "PR:P55075") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "fibroblast growth factor 8 (human)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cathepsin K (mouse)) - -AnnotationAssertion(Annotation( "OMA:P55097") Annotation( "PRO:DNx") "A cathepsin K that is encoded in the genome of mouse.") -AnnotationAssertion( "UniProtKB:P55097") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mCTSK") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P55097") Annotation( ) "Ctsk") -AnnotationAssertion( "PR:P55097") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "cathepsin K (mouse)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cadherin-5 (mouse)) - -AnnotationAssertion(Annotation( "OMA:P55284") Annotation( "PRO:DNx") "A cadherin-5 that is encoded in the genome of mouse.") -AnnotationAssertion( "UniProtKB:P55284") -AnnotationAssertion(Annotation( "UniProtKB:P55284") "CD144 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P55284") "VE-cadherin (mouse)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mCDH5") -AnnotationAssertion(Annotation( "UniProtKB:P55284") "vascular endothelial cadherin (mouse)") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P55284") Annotation( ) "Cdh5") -AnnotationAssertion( "PR:P55284") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "cadherin-5 (mouse)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (V(D)J recombination-activating protein 2 (human)) - -AnnotationAssertion(Annotation( "PRO:CNA") Annotation( "UniProtKB:P55895") "A V(D)J recombination-activating protein 2 that is encoded in the genome of human.") -AnnotationAssertion(Annotation(rdfs:label "PR:P55895 located_in GO:0005654") "Reactome:R-HSA-5692675") -AnnotationAssertion( "UniProtKB:P55895") -AnnotationAssertion(Annotation( "UniProtKB:P55895") "RAG-2 (human)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hRAG2") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P55895") Annotation( ) "RAG2") -AnnotationAssertion( "PR:P55895") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "V(D)J recombination-activating protein 2 (human)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 (mouse)) - -AnnotationAssertion(Annotation( "OMA:P56528") Annotation( "PRO:DNx") "An ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 that is encoded in the genome of mouse.") -AnnotationAssertion( "UniProtKB:P56528") -AnnotationAssertion(Annotation( "UniProtKB:P56528") "2'-phospho-ADP-ribosyl cyclase (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P56528") "2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P56528") "2'-phospho-cyclic-ADP-ribose transferase (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P56528") "ADP-ribosyl cyclase 1 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P56528") "ADPRC 1 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P56528") "CD38 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P56528") "I-19 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P56528") "NIM-R5 antigen (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P56528") "cADPr hydrolase 1 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:P56528") "cyclic ADP-ribose hydrolase 1 (mouse)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mCD38") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P56528") Annotation( ) "Cd38") -AnnotationAssertion( "PR:P56528") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 (mouse)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (insulin (chicken)) - -AnnotationAssertion(Annotation( "OMA:P67970") Annotation( "PRO:DNx") "An insulin gene translation product that is encoded in the genome of chicken.") -AnnotationAssertion( "UniProtKB:P67970") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "chick-INS") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P67970") Annotation( ) "INS") -AnnotationAssertion( "PR:P67970") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "insulin (chicken)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (nuclear factor NF-kappa-B p100 subunit (chicken)) - -AnnotationAssertion(Annotation( "PRO:DNx") "A nuclear factor NF-kappa-B p100 subunit that is encoded in the genome of chicken.") -AnnotationAssertion( "UniProtKB:P98150") -AnnotationAssertion(Annotation( "UniProtKB:P98150") "DNA-binding factor KBF2 (chicken)") -AnnotationAssertion(Annotation( "UniProtKB:P98150") "Lyt-10 (chicken)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "chick-NFKB2") -AnnotationAssertion(Annotation( "UniProtKB:P98150") "nuclear factor NF-kappa-B p97 subunit (chicken)") -AnnotationAssertion(Annotation( "UniProtKB:P98150") "nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (chicken)") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:P98150") Annotation( ) "NFKB2") -AnnotationAssertion( "PR:P98150") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "nuclear factor NF-kappa-B p100 subunit (chicken)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (receptor-type tyrosine-protein kinase FLT3 (mouse)) - -AnnotationAssertion(Annotation( "OMA:Q00342") Annotation( "PRO:DNx") "A receptor-type tyrosine-protein kinase FLT3 that is encoded in the genome of mouse.") -AnnotationAssertion( "UniProtKB:Q00342") -AnnotationAssertion(Annotation( "UniProtKB:Q00342") "CD135 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:Q00342") "FL cytokine receptor (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:Q00342") "FLK-2 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:Q00342") "FLT-3 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:Q00342") "fetal liver kinase 2 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:Q00342") "fms-like tyrosine kinase 3 (mouse)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mFLT3") -AnnotationAssertion(Annotation( "UniProtKB:Q00342") "tyrosine-protein kinase receptor flk-2 (mouse)") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:Q00342") Annotation( ) "Flk-2") -AnnotationAssertion(Annotation( "UniProtKB:Q00342") Annotation( ) "Flt-3") -AnnotationAssertion(Annotation( "UniProtKB:Q00342") Annotation( ) "Flt3") -AnnotationAssertion( "PR:Q00342") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "receptor-type tyrosine-protein kinase FLT3 (mouse)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (nuclear factor NF-kappa-B p100 subunit (human)) - -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( "UniProtKB:Q00653") "A nuclear factor NF-kappa-B p100 subunit that is encoded in the genome of human.") -AnnotationAssertion(Annotation(rdfs:label "PR:Q00653 located_in GO:0005829") "Reactome:R-HSA-2677931") -AnnotationAssertion( "UniProtKB:Q00653") -AnnotationAssertion(Annotation( "UniProtKB:Q00653") "DNA-binding factor KBF2 (human)") -AnnotationAssertion(Annotation( "UniProtKB:Q00653") "H2TF1 (human)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hNFKB2") -AnnotationAssertion(Annotation( "UniProtKB:Q00653") "lymphocyte translocation chromosome 10 protein (human)") -AnnotationAssertion(Annotation( "UniProtKB:Q00653") "nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (human)") -AnnotationAssertion(Annotation( "UniProtKB:Q00653") "oncogene Lyt-10 (human)") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:Q00653") Annotation( ) "LYT10") -AnnotationAssertion(Annotation( "UniProtKB:Q00653") Annotation( ) "NFKB2") -AnnotationAssertion( "PR:Q00653") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "nuclear factor NF-kappa-B p100 subunit (human)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (interleukin-5 receptor subunit alpha (human)) - -AnnotationAssertion(Annotation( "PRO:WCB") Annotation( "UniProtKB:Q01344") "An interleukin-5 receptor subunit alpha that is encoded in the genome of human.") -AnnotationAssertion( "UniProtKB:Q01344") -AnnotationAssertion(Annotation( "UniProtKB:Q01344") "CD125 (human)") -AnnotationAssertion(Annotation( "UniProtKB:Q01344") "CDw125 (human)") -AnnotationAssertion(Annotation( "UniProtKB:Q01344") "IL-5 receptor subunit alpha (human)") -AnnotationAssertion(Annotation( "UniProtKB:Q01344") "IL-5R subunit alpha (human)") -AnnotationAssertion(Annotation( "UniProtKB:Q01344") "IL-5R-alpha (human)") -AnnotationAssertion(Annotation( "UniProtKB:Q01344") "IL-5RA (human)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hIL5RA") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:Q01344") Annotation( ) "IL5R") -AnnotationAssertion(Annotation( "UniProtKB:Q01344") Annotation( ) "IL5RA") -AnnotationAssertion( "PR:Q01344") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "interleukin-5 receptor subunit alpha (human)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (paired box protein Pax-5 (human)) - -AnnotationAssertion(Annotation( "PRO:WCB") Annotation( "UniProtKB:Q02548") "A paired box protein PAX-5 that is encoded in the genome of human.") -AnnotationAssertion(Annotation(rdfs:label "PR:Q02548 located_in GO:0005654") "Reactome:R-HSA-158583") -AnnotationAssertion( "UniProtKB:Q02548") -AnnotationAssertion(Annotation( "UniProtKB:Q02548") "B-cell-specific transcription factor (human)") -AnnotationAssertion(Annotation( "UniProtKB:Q02548") "BSAP (human)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hPAX5") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:Q02548") Annotation( ) "PAX5") -AnnotationAssertion( "PR:Q02548") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "paired box protein Pax-5 (human)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (paired box protein Pax-5 (mouse)) - -AnnotationAssertion(Annotation( "OMA:Q02650") Annotation( "PRO:DNx") "A paired box protein PAX-5 that is encoded in the genome of mouse.") -AnnotationAssertion( "UniProtKB:Q02650") -AnnotationAssertion(Annotation( "UniProtKB:Q02650") "B-cell-specific transcription factor (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:Q02650") "BSAP (mouse)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mPAX5") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:Q02650") Annotation( ) "Pax-5") -AnnotationAssertion(Annotation( "UniProtKB:Q02650") Annotation( ) "Pax5") -AnnotationAssertion( "PR:Q02650") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "paired box protein Pax-5 (mouse)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (urokinase plasminogen activator surface receptor (human)) - -AnnotationAssertion(Annotation( "PRO:WCB") Annotation( "UniProtKB:Q03405") "A urokinase plasminogen activator surface receptor that is encoded in the genome of human.") -AnnotationAssertion( "UniProtKB:Q03405") -AnnotationAssertion(Annotation( "UniProtKB:Q03405") "CD87 (human)") -AnnotationAssertion(Annotation( "UniProtKB:Q03405") "U-PAR (human)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hPLAUR") -AnnotationAssertion(Annotation( "UniProtKB:Q03405") "monocyte activation antigen Mo3 (human)") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:Q03405") Annotation( ) "MO3") -AnnotationAssertion(Annotation( "UniProtKB:Q03405") Annotation( ) "PLAUR") -AnnotationAssertion(Annotation( "UniProtKB:Q03405") Annotation( ) "UPAR") -AnnotationAssertion( "PR:Q03405") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "urokinase plasminogen activator surface receptor (human)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (tartrate-resistant acid phosphatase type 5 (mouse)) - -AnnotationAssertion(Annotation( "OMA:Q05117") Annotation( "PRO:DNx") "A tartrate-resistant acid phosphatase type 5 that is encoded in the genome of mouse.") -AnnotationAssertion( "UniProtKB:Q05117") -AnnotationAssertion(Annotation( "UniProtKB:Q05117") "TR-AP (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:Q05117") "TrATPase (mouse)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mACP5") -AnnotationAssertion(Annotation( "UniProtKB:Q05117") "tartrate-resistant acid ATPase (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:Q05117") "type 5 acid phosphatase (mouse)") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:Q05117") Annotation( ) "Acp5") -AnnotationAssertion(Annotation( "UniProtKB:Q05117") Annotation( ) "T5ap") -AnnotationAssertion(Annotation( "UniProtKB:Q05117") Annotation( ) "Trap") -AnnotationAssertion( "PR:Q05117") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "tartrate-resistant acid phosphatase type 5 (mouse)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (glutamyl aminopeptidase (human)) - -AnnotationAssertion(Annotation( "PRO:WCB") Annotation( "UniProtKB:Q07075") "A glutamyl aminopeptidase that is encoded in the genome of human.") -AnnotationAssertion(Annotation( "UniProtKB:Q07075") "EAP (human)") -AnnotationAssertion(Annotation(rdfs:label "PR:Q07075 located_in GO:0005886") "Reactome:R-HSA-2022341") -AnnotationAssertion( "UniProtKB:Q07075") -AnnotationAssertion(Annotation( "UniProtKB:Q07075") "AP-A (human)") -AnnotationAssertion(Annotation( "UniProtKB:Q07075") "CD249 (human)") -AnnotationAssertion(Annotation( "UniProtKB:Q07075") "aminopeptidase A (human)") -AnnotationAssertion(Annotation( "UniProtKB:Q07075") "differentiation antigen gp160 (human)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hENPEP") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:Q07075") Annotation( ) "ENPEP") -AnnotationAssertion( "PR:Q07075") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "glutamyl aminopeptidase (human)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (natural killer cell receptor 2B4 (mouse)) - -AnnotationAssertion(Annotation( "OMA:Q07763") Annotation( "PRO:DNx") "A natural killer cell receptor 2B4 that is encoded in the genome of mouse.") -AnnotationAssertion( "UniProtKB:Q07763") -AnnotationAssertion(Annotation( "UniProtKB:Q07763") "CD244 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:Q07763") "NK cell type I receptor protein 2B4 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:Q07763") "NKR2B4 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:Q07763") "SLAM family member 4 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:Q07763") "SLAMF4 (mouse)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mCD244") -AnnotationAssertion(Annotation( "UniProtKB:Q07763") "non-MHC restricted killing associated (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:Q07763") "signaling lymphocytic activation molecule 4 (mouse)") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:Q07763") Annotation( ) "2b4") -AnnotationAssertion(Annotation( "UniProtKB:Q07763") Annotation( ) "Cd244") -AnnotationAssertion(Annotation( "UniProtKB:Q07763") Annotation( ) "Nmrk") -AnnotationAssertion( "PR:Q07763") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "natural killer cell receptor 2B4 (mouse)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (mast/stem cell growth factor receptor Kit (chicken)) - -AnnotationAssertion(Annotation( "OMA:Q08156") Annotation( "PANTHER:PTHR24416:SF238") Annotation( "PRO:DNx") "A mast/stem cell growth factor receptor that is encoded in the genome of chicken.") -AnnotationAssertion( "UniProtKB:Q08156") -AnnotationAssertion(Annotation( "UniProtKB:Q08156") "SCFR (chicken)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "chick-KIT") -AnnotationAssertion(Annotation( "UniProtKB:Q08156") "proto-oncogene c-Kit (chicken)") -AnnotationAssertion(Annotation( "UniProtKB:Q08156") "tyrosine-protein kinase Kit (chicken)") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:Q08156") Annotation( ) "KIT") -AnnotationAssertion( "PR:Q08156") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "mast/stem cell growth factor receptor Kit (chicken)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (signaling lymphocytic activation molecule (human)) - -AnnotationAssertion(Annotation( "PRO:WCB") Annotation( "UniProtKB:Q13291") "A SLAM family member 1 that is encoded in the genome of human.") -AnnotationAssertion( "UniProtKB:Q13291") -AnnotationAssertion(Annotation( "UniProtKB:Q13291") "CD150 (human)") -AnnotationAssertion(Annotation( "UniProtKB:Q13291") "CDw150 (human)") -AnnotationAssertion(Annotation( "UniProtKB:Q13291") "IPO-3 (human)") -AnnotationAssertion(Annotation( "UniProtKB:Q13291") "SLAM family member 1 (human)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hSLAMF1") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:Q13291") Annotation( ) "SLAM") -AnnotationAssertion(Annotation( "UniProtKB:Q13291") Annotation( ) "SLAMF1") -AnnotationAssertion( "PR:Q13291") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "signaling lymphocytic activation molecule (human)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (sonic hedgehog protein (human)) - -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( "UniProtKB:Q15465") "A sonic hedgehog protein that is encoded in the genome of human.") -AnnotationAssertion( "UniProtKB:Q15465") -AnnotationAssertion(Annotation( "UniProtKB:Q15465") "HHG-1 (human)") -AnnotationAssertion(Annotation( "UniProtKB:Q15465") "Shh unprocessed N-terminal signaling and C-terminal autoprocessing domains (human)") -AnnotationAssertion(Annotation( "UniProtKB:Q15465") "ShhNC (human)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hSHH") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:Q15465") Annotation( ) "SHH") -AnnotationAssertion( "PR:Q15465") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "sonic hedgehog protein (human)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (scavenger receptor cysteine-rich type 1 protein M130 (mouse)) - -AnnotationAssertion(Annotation( "OMA:Q2VLH6") Annotation( "PRO:DNx") "A scavenger receptor cysteine-rich type 1 protein M130 that is encoded in the genome of mouse.") -AnnotationAssertion( "UniProtKB:Q2VLH6") -AnnotationAssertion(Annotation( "UniProtKB:Q2VLH6") "CD163 (mouse)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mCD163") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:Q2VLH6") Annotation( ) "Cd163") -AnnotationAssertion(Annotation( "UniProtKB:Q2VLH6") Annotation( ) "M130") -AnnotationAssertion( "PR:Q2VLH6") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "scavenger receptor cysteine-rich type 1 protein M130 (mouse)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (neprilysin (mouse)) - -AnnotationAssertion(Annotation( "OMA:Q61391") Annotation( "PRO:DNx") "A neprilysin that is encoded in the genome of mouse.") -AnnotationAssertion( "UniProtKB:Q61391") -AnnotationAssertion(Annotation( "UniProtKB:Q61391") "CD10 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:Q61391") "NEP (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:Q61391") "SFE (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:Q61391") "atriopeptidase (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:Q61391") "enkephalinase (mouse)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mMME") -AnnotationAssertion(Annotation( "UniProtKB:Q61391") "neutral endopeptidase (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:Q61391") "neutral endopeptidase 24.11 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:Q61391") "skin fibroblast elastase (mouse)") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:Q61391") Annotation( ) "Mme") -AnnotationAssertion( "PR:Q61391") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "neprilysin (mouse)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (forkhead box protein N1 (mouse)) - -AnnotationAssertion(Annotation( "OMA:Q61575") Annotation( "PRO:DNx") "A forkhead box protein N1 that is encoded in the genome of mouse.") -AnnotationAssertion( "UniProtKB:Q61575") -AnnotationAssertion(Annotation( "UniProtKB:Q61575") "HFH-11 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:Q61575") "HNF-3/forkhead homolog 11 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:Q61575") "hepatocyte nuclear factor 3 forkhead homolog 11 (mouse)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mFOXN1") -AnnotationAssertion(Annotation( "UniProtKB:Q61575") "winged-helix transcription factor nude (mouse)") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:Q61575") Annotation( ) "Fkh19") -AnnotationAssertion(Annotation( "UniProtKB:Q61575") Annotation( ) "Foxn1") -AnnotationAssertion(Annotation( "UniProtKB:Q61575") Annotation( ) "Hfh11") -AnnotationAssertion(Annotation( "UniProtKB:Q61575") Annotation( ) "Whn") -AnnotationAssertion( "PR:Q61575") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "forkhead box protein N1 (mouse)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (sonic hedgehog protein (mouse)) - -AnnotationAssertion(Annotation( "OMA:Q62226") Annotation( "PRO:DNx") "A sonic hedgehog protein that is encoded in the genome of mouse.") -AnnotationAssertion( "UniProtKB:Q62226") -AnnotationAssertion(Annotation( "UniProtKB:Q62226") "HHG-1 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:Q62226") "SHH (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:Q62226") "Shh unprocessed N-terminal signaling and C-terminal autoprocessing domains (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:Q62226") "ShhNC (mouse)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mSHH") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:Q62226") Annotation( ) "Hhg1") -AnnotationAssertion(Annotation( "UniProtKB:Q62226") Annotation( ) "Shh") -AnnotationAssertion( "PR:Q62226") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "sonic hedgehog protein (mouse)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (transferrin receptor protein 1 (mouse)) - -AnnotationAssertion(Annotation( "OMA:Q62351") Annotation( "PRO:DNx") "A transferrin receptor protein 1 that is encoded in the genome of mouse.") -AnnotationAssertion( "UniProtKB:Q62351") -AnnotationAssertion(Annotation( "UniProtKB:Q62351") "CD71 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:Q62351") "TfR (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:Q62351") "TfR1 (mouse)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mTFRC") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:Q62351") "TR (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:Q62351") Annotation( ) "Tfrc") -AnnotationAssertion(Annotation( "UniProtKB:Q62351") Annotation( ) "Trfr") -AnnotationAssertion( "PR:Q62351") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "transferrin receptor protein 1 (mouse)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (endoglin (mouse)) - -AnnotationAssertion(Annotation( "OMA:Q63961") Annotation( "PRO:DNx") "An endoglin that is encoded in the genome of mouse.") -AnnotationAssertion( "UniProtKB:Q63961") -AnnotationAssertion(Annotation( "UniProtKB:Q63961") "CD105 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:Q63961") "cell surface MJ7/18 antigen (mouse)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mENG") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:Q63961") Annotation( ) "Edg") -AnnotationAssertion(Annotation( "UniProtKB:Q63961") Annotation( ) "Eng") -AnnotationAssertion( "PR:Q63961") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "endoglin (mouse)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (myeloid cell surface antigen CD33 (mouse)) - -AnnotationAssertion(Annotation( "PRO:WCB") "A CD33 molecule that is encoded in the genome of mouse.") -AnnotationAssertion( "UniProtKB:Q63994") -AnnotationAssertion(Annotation( "UniProtKB:Q63994") "CD33 (mouse)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mCD33") -AnnotationAssertion(Annotation( "UniProtKB:Q63994") "sialic acid-binding Ig-like lectin 3 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:Q63994") "siglec-3 (mouse)") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:Q63994") Annotation( ) "Cd33") -AnnotationAssertion(Annotation( "UniProtKB:Q63994") Annotation( ) "Siglec3") -AnnotationAssertion( "PR:Q63994") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "myeloid cell surface antigen CD33 (mouse)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (hematopoietic progenitor cell antigen CD34 (mouse)) - -AnnotationAssertion(Annotation( "OMA:Q64314") Annotation( "PRO:DNx") "A CD34 molecule that is encoded in the genome of mouse.") -AnnotationAssertion( "UniProtKB:Q64314") -AnnotationAssertion(Annotation( "UniProtKB:Q64314") "CD34 (mouse)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mCD34") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:Q64314") Annotation( ) "Cd34") -AnnotationAssertion( "PR:Q64314") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "hematopoietic progenitor cell antigen CD34 (mouse)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (lactosylceramide 4-alpha-galactosyltransferase (mouse)) - -AnnotationAssertion(Annotation( "OMA:Q67BJ4") Annotation( "PRO:DNx") "A lactosylceramide 4-alpha-galactosyltransferase that is encoded in the genome of mouse.") -AnnotationAssertion( "UniProtKB:Q67BJ4") -AnnotationAssertion(Annotation( "UniProtKB:Q67BJ4") "Gb3 synthase (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:Q67BJ4") "UDP-galactose:beta-D-galactosyl-beta1-R 4-alpha-D-galactosyltransferase (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:Q67BJ4") "alpha-1,4-galactosyltransferase (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:Q67BJ4") "alpha4Gal-T1 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:Q67BJ4") "globotriaosylceramide synthase (mouse)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mA4GALT") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:Q67BJ4") Annotation( ) "A4galt") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( "UniProtKB:Q67BJ4") "alpha-1,4-N-acetylglucosaminyltransferase (mouse)") -AnnotationAssertion( "PR:Q67BJ4") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "lactosylceramide 4-alpha-galactosyltransferase (mouse)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (scavenger receptor cysteine-rich type 1 protein M130 (human)) - -AnnotationAssertion(Annotation( "PRO:WCB") Annotation( "UniProtKB:Q86VB7") "A scavenger receptor cysteine-rich type 1 protein M130 that is encoded in the genome of human.") -AnnotationAssertion( "UniProtKB:Q86VB7") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hCD163") -AnnotationAssertion(Annotation( "UniProtKB:Q86VB7") "hemoglobin scavenger receptor (human)") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:Q86VB7") Annotation( ) "CD163") -AnnotationAssertion(Annotation( "UniProtKB:Q86VB7") Annotation( ) "M130") -AnnotationAssertion( "PR:Q86VB7") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "scavenger receptor cysteine-rich type 1 protein M130 (human)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (cadherin-5 (chicken)) - -AnnotationAssertion(Annotation( "OMA:Q8AYD0") Annotation( "PANTHER:PTHR24027:SF44") Annotation( "PRO:DNx") "A cadherin-5 that is encoded in the genome of chicken.") -AnnotationAssertion( "UniProtKB:Q8AYD0") -AnnotationAssertion(Annotation( "UniProtKB:Q8AYD0") "VE-cadherin (chicken)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "chick-CDH5") -AnnotationAssertion(Annotation( "UniProtKB:Q8AYD0") "vascular endothelial cadherin (chicken)") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:Q8AYD0") Annotation( ) "CDH5") -AnnotationAssertion( "PR:Q8AYD0") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "cadherin-5 (chicken)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (SCO-spondin (mouse)) - -AnnotationAssertion(Annotation( "PRO:DNx") "A SCO-spondin that is encoded in the genome of mouse.") -AnnotationAssertion( "UniProtKB:Q8CG65") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mSSPO") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:Q8CG65") Annotation( ) "Sspo") -AnnotationAssertion( "PR:Q8CG65") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "SCO-spondin (mouse)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (C-type lectin domain family 4 member K (mouse)) - -AnnotationAssertion(Annotation( "OMA:Q8VBX4") Annotation( "PRO:DNx") "A C-type lectin domain family 4 member K that is encoded in the genome of mouse.") -AnnotationAssertion( "UniProtKB:Q8VBX4") -AnnotationAssertion(Annotation( "UniProtKB:Q8VBX4") "CD207 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:Q8VBX4") "langerin (mouse)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mCD207") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:Q8VBX4") Annotation( ) "Cd207") -AnnotationAssertion(Annotation( "UniProtKB:Q8VBX4") Annotation( ) "Clec4k") -AnnotationAssertion( "PR:Q8VBX4") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "C-type lectin domain family 4 member K (mouse)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (spondin-1 (mouse)) - -AnnotationAssertion(Annotation( "OMA:Q8VCC9") Annotation( "PRO:DNx") "A spondin-1 that is encoded in the genome of mouse.") -AnnotationAssertion( "UniProtKB:Q8VCC9") -AnnotationAssertion(Annotation( "UniProtKB:Q8VCC9") "F-spondin (mouse)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mSPON1") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:Q8VCC9") Annotation( ) "Spon1") -AnnotationAssertion( "PR:Q8VCC9") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "spondin-1 (mouse)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (fibroblast growth factor 8 (chicken)) - -AnnotationAssertion(Annotation( "OMA:Q90722") Annotation( "PANTHER:PTHR11486:SF2") Annotation( "PRO:DNx") "A fibroblast growth factor 8 that is encoded in the genome of chicken.") -AnnotationAssertion( "UniProtKB:Q90722") -AnnotationAssertion(Annotation( "UniProtKB:Q90722") "FGF-8 (chicken)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "chick-FGF8") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:Q90722") Annotation( ) "FGF8") -AnnotationAssertion(Annotation( "UniProtKB:Q90722") "HBGF-8 (chicken)") -AnnotationAssertion(Annotation( "UniProtKB:Q90722") "heparin-binding growth factor 8 (chicken)") -AnnotationAssertion( "PR:Q90722") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "fibroblast growth factor 8 (chicken)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (transferrin receptor protein 1 (chicken)) - -AnnotationAssertion(Annotation( "PANTHER:PTHR10404:SF26") Annotation( "PRO:DNx") "A transferrin receptor protein 1 that is encoded in the genome of chicken.") -AnnotationAssertion( "UniProtKB:Q90997") -AnnotationAssertion(Annotation( "UniProtKB:Q90997") "TR (chicken)") -AnnotationAssertion(Annotation( "UniProtKB:Q90997") "TfR (chicken)") -AnnotationAssertion(Annotation( "UniProtKB:Q90997") "TfR1 (chicken)") -AnnotationAssertion(Annotation( "UniProtKB:Q90997") "Trfr (chicken)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "chick-TFRC") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:Q90997") Annotation( ) "TFRC") -AnnotationAssertion( "PR:Q90997") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "transferrin receptor protein 1 (chicken)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (sonic hedgehog protein (chicken)) - -AnnotationAssertion(Annotation( "PANTHER:PTHR11889:SF16") Annotation( "PRO:DNx") "A sonic hedgehog protein that is encoded in the genome of chicken.") -AnnotationAssertion( "UniProtKB:Q91035") -AnnotationAssertion(Annotation( "UniProtKB:Q91035") "Shh unprocessed N-terminal signaling and C-terminal autoprocessing domains (chicken)") -AnnotationAssertion(Annotation( "UniProtKB:Q91035") "ShhNC (chicken)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "chick-SHH") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:Q91035") Annotation( ) "SHH") -AnnotationAssertion( "PR:Q91035") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "sonic hedgehog protein (chicken)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (natural killer cell receptor 2B4 (human)) - -AnnotationAssertion(Annotation( "PRO:WCB") Annotation( "UniProtKB:Q9BZW8") "A natural killer cell receptor 2B4 that is encoded in the genome of human.") -AnnotationAssertion( "UniProtKB:Q9BZW8") -AnnotationAssertion(Annotation( "UniProtKB:Q9BZW8") "NAIL (human)") -AnnotationAssertion(Annotation( "UniProtKB:Q9BZW8") "NK cell activation-inducing ligand (human)") -AnnotationAssertion(Annotation( "UniProtKB:Q9BZW8") "NK cell type I receptor protein 2B4 (human)") -AnnotationAssertion(Annotation( "UniProtKB:Q9BZW8") "NKR2B4 (human)") -AnnotationAssertion(Annotation( "UniProtKB:Q9BZW8") "SLAM family member 4 (human)") -AnnotationAssertion(Annotation( "UniProtKB:Q9BZW8") "SLAMF4 (human)") -AnnotationAssertion(Annotation( "UniProtKB:Q9BZW8") "h2B4 (human)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hCD244") -AnnotationAssertion(Annotation( "UniProtKB:Q9BZW8") "signaling lymphocytic activation molecule 4 (human)") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:Q9BZW8") Annotation( ) "2B4") -AnnotationAssertion(Annotation( "UniProtKB:Q9BZW8") Annotation( ) "CD244") -AnnotationAssertion( "PR:Q9BZW8") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "natural killer cell receptor 2B4 (human)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (spondin-1 (human)) - -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( "UniProtKB:Q9HCB6") "A spondin-1 that is encoded in the genome of human.") -AnnotationAssertion( "UniProtKB:Q9HCB6") -AnnotationAssertion(Annotation( "UniProtKB:Q9HCB6") "F-spondin (human)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hSPON1") -AnnotationAssertion(Annotation( "UniProtKB:Q9HCB6") "vascular smooth muscle cell growth-promoting factor (human)") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:Q9HCB6") Annotation( ) "KIAA0762") -AnnotationAssertion(Annotation( "UniProtKB:Q9HCB6") Annotation( ) "SPON1") -AnnotationAssertion(Annotation( "UniProtKB:Q9HCB6") Annotation( ) "VSGP") -AnnotationAssertion( "PR:Q9HCB6") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "spondin-1 (human)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (lactosylceramide 4-alpha-galactosyltransferase (human)) - -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( "UniProtKB:Q9NPC4") "A lactosylceramide 4-alpha-galactosyltransferase that is encoded in the genome of human.") -AnnotationAssertion( "UniProtKB:Q9NPC4") -AnnotationAssertion(Annotation( "UniProtKB:Q9NPC4") "CD77 synthase (human)") -AnnotationAssertion(Annotation( "UniProtKB:Q9NPC4") "Gb3 synthase (human)") -AnnotationAssertion(Annotation( "UniProtKB:Q9NPC4") "P1/Pk synthase (human)") -AnnotationAssertion(Annotation( "UniProtKB:Q9NPC4") "UDP-galactose:beta-D-galactosyl-beta1-R 4-alpha-D-galactosyltransferase (human)") -AnnotationAssertion(Annotation( "UniProtKB:Q9NPC4") "alpha-1,4-galactosyltransferase (human)") -AnnotationAssertion(Annotation( "UniProtKB:Q9NPC4") "alpha4Gal-T1 (human)") -AnnotationAssertion(Annotation( "UniProtKB:Q9NPC4") "globotriaosylceramide synthase (human)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hA4GALT") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:Q9NPC4") Annotation( ) "A14GALT") -AnnotationAssertion(Annotation( "UniProtKB:Q9NPC4") Annotation( ) "A4GALT") -AnnotationAssertion(Annotation( "UniProtKB:Q9NPC4") Annotation( ) "A4GALT1") -AnnotationAssertion(Annotation( "UniProtKB:Q9NPC4") "alpha-1,4-N-acetylglucosaminyltransferase (human)") -AnnotationAssertion( "PR:Q9NPC4") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "lactosylceramide 4-alpha-galactosyltransferase (human)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (complement component C1q receptor (human)) - -AnnotationAssertion(Annotation( "PRO:WCB") Annotation( "UniProtKB:Q9NPY3") "A complement component C1q receptor that is encoded in the genome of human.") -AnnotationAssertion( "UniProtKB:Q9NPY3") -AnnotationAssertion(Annotation( "UniProtKB:Q9NPY3") "C1q/MBL/SPA receptor (human)") -AnnotationAssertion(Annotation( "UniProtKB:Q9NPY3") "C1qR (human)") -AnnotationAssertion(Annotation( "UniProtKB:Q9NPY3") "C1qR(p) (human)") -AnnotationAssertion(Annotation( "UniProtKB:Q9NPY3") "C1qRp (human)") -AnnotationAssertion(Annotation( "UniProtKB:Q9NPY3") "CDw93 (human)") -AnnotationAssertion(Annotation( "UniProtKB:Q9NPY3") "complement component 1 q subcomponent receptor 1 (human)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hCD93") -AnnotationAssertion(Annotation( "UniProtKB:Q9NPY3") "matrix-remodeling-associated protein 4 (human)") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:Q9NPY3") Annotation( ) "C1QR1") -AnnotationAssertion(Annotation( "UniProtKB:Q9NPY3") Annotation( ) "CD93") -AnnotationAssertion(Annotation( "UniProtKB:Q9NPY3") Annotation( ) "MXRA4") -AnnotationAssertion( "PR:Q9NPY3") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "complement component C1q receptor (human)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (integrin alpha-IIb (mouse)) - -AnnotationAssertion(Annotation( "OMA:Q9QUM0") Annotation( "PRO:DNx") "An integrin alpha-IIb that is encoded in the genome of mouse.") -AnnotationAssertion( "UniProtKB:Q9QUM0") -AnnotationAssertion(Annotation( "UniProtKB:Q9QUM0") "CD41 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:Q9QUM0") "GPIIb (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:Q9QUM0") "GPalpha IIb (mouse)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mITGA2B") -AnnotationAssertion(Annotation( "UniProtKB:Q9QUM0") "platelet membrane glycoprotein IIb (mouse)") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:Q9QUM0") Annotation( ) "Itga2b") -AnnotationAssertion( "PR:Q9QUM0") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "integrin alpha-IIb (mouse)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (signaling lymphocytic activation molecule (mouse)) - -AnnotationAssertion(Annotation( "OMA:Q9QUM4") Annotation( "PRO:DNx") "A SLAM family member 1 that is encoded in the genome of mouse.") -AnnotationAssertion( "UniProtKB:Q9QUM4") -AnnotationAssertion(Annotation( "UniProtKB:Q9QUM4") "CD150 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:Q9QUM4") "SLAM family member 1 (mouse)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mSLAMF1") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:Q9QUM4") Annotation( ) "Slam") -AnnotationAssertion(Annotation( "UniProtKB:Q9QUM4") Annotation( ) "Slamf1") -AnnotationAssertion( "PR:Q9QUM4") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "signaling lymphocytic activation molecule (mouse)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (integrin alpha-X (mouse)) - -AnnotationAssertion(Annotation( "OMA:Q9QXH4") Annotation( "PRO:DNx") "An integrin alpha-X that is encoded in the genome of mouse.") -AnnotationAssertion( "UniProtKB:Q9QXH4") -AnnotationAssertion(Annotation( "UniProtKB:Q9QXH4") "CD11 antigen-like family member C (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:Q9QXH4") "CD11c (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:Q9QXH4") "leukocyte adhesion glycoprotein p150,95 alpha chain (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:Q9QXH4") "leukocyte adhesion receptor p150,95 (mouse)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mITGAX") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:Q9QXH4") Annotation( ) "Itgax") -AnnotationAssertion( "PR:Q9QXH4") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "integrin alpha-X (mouse)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (C-type lectin domain family 4 member K (human)) - -AnnotationAssertion(Annotation( "PRO:WCB") Annotation( "UniProtKB:Q9UJ71") "A C-type lectin domain family 4 member K that is encoded in the genome of human.") -AnnotationAssertion(Annotation(rdfs:label "PR:Q9UJ71 located_in GO:0005886") "Reactome:R-HSA-1216519") -AnnotationAssertion(Annotation(rdfs:label "PR:Q9UJ71 located_in GO:0030669") "Reactome:R-HSA-1236762") -AnnotationAssertion(Annotation(rdfs:label "PR:Q9UJ71 located_in GO:0031901") "Reactome:R-HSA-1236852") -AnnotationAssertion( "UniProtKB:Q9UJ71") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hCD207") -AnnotationAssertion(Annotation( "UniProtKB:Q9UJ71") "langerin (human)") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:Q9UJ71") Annotation( ) "CD207") -AnnotationAssertion(Annotation( "UniProtKB:Q9UJ71") Annotation( ) "CLEC4K") -AnnotationAssertion( "PR:Q9UJ71") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "C-type lectin domain family 4 member K (human)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (Pax-5 protein (chicken)) - -AnnotationAssertion(Annotation( "OMA:Q9W601") Annotation( "PRO:DNx") "A paired box protein PAX-5 that is encoded in the genome of chicken.") -AnnotationAssertion( "UniProtKB:Q9W601") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "chick-PAX5") -AnnotationAssertion( "protein") -AnnotationAssertion( "PR:Q9W601") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "Pax-5 protein (chicken)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (spondin-1 (chicken)) - -AnnotationAssertion(Annotation( "PANTHER:PTHR11311:SF2") Annotation( "PRO:DNx") "A spondin-1 that is encoded in the genome of chicken.") -AnnotationAssertion( "UniProtKB:Q9W770") -AnnotationAssertion(Annotation( "UniProtKB:Q9W770") "F-spondin (chicken)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "chick-SPON1") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:Q9W770") Annotation( ) "SPON1") -AnnotationAssertion( "PR:Q9W770") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "spondin-1 (chicken)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (nuclear factor NF-kappa-B p100 subunit (mouse)) - -AnnotationAssertion(Annotation( "OMA:Q9WTK5") Annotation( "PRO:DNx") "A nuclear factor NF-kappa-B p100 subunit that is encoded in the genome of mouse.") -AnnotationAssertion( "UniProtKB:Q9WTK5") -AnnotationAssertion(Annotation( "UniProtKB:Q9WTK5") "DNA-binding factor KBF2 (mouse)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mNFKB2") -AnnotationAssertion(Annotation( "UniProtKB:Q9WTK5") "nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (mouse)") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:Q9WTK5") Annotation( ) "Nfkb2") -AnnotationAssertion( "PR:Q9WTK5") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "nuclear factor NF-kappa-B p100 subunit (mouse)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (tumor necrosis factor receptor superfamily member 11A (human)) - -AnnotationAssertion(Annotation( "PRO:WCB") Annotation( "UniProtKB:Q9Y6Q6") "A tumor necrosis factor receptor superfamily member 11A that is encoded in the genome of human.") -AnnotationAssertion( "UniProtKB:Q9Y6Q6") -AnnotationAssertion(Annotation( "UniProtKB:Q9Y6Q6") "CD265 (human)") -AnnotationAssertion(Annotation( "UniProtKB:Q9Y6Q6") "ODFR (human)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hTNFRSF11A") -AnnotationAssertion(Annotation( "UniProtKB:Q9Y6Q6") "osteoclast differentiation factor receptor (human)") -AnnotationAssertion(Annotation( "UniProtKB:Q9Y6Q6") "receptor activator of NF-KB (human)") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:Q9Y6Q6") Annotation( ) "RANK") -AnnotationAssertion(Annotation( "UniProtKB:Q9Y6Q6") Annotation( ) "TNFRSF11A") -AnnotationAssertion( "PR:Q9Y6Q6") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "tumor necrosis factor receptor superfamily member 11A (human)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - -# Class: (CX3C chemokine receptor 1 (mouse)) - -AnnotationAssertion(Annotation( "OMA:Q9Z0D9") Annotation( "PRO:DNx") "A CX3C chemokine receptor 1 that is encoded in the genome of mouse.") -AnnotationAssertion( "UniProtKB:Q9Z0D9") -AnnotationAssertion(Annotation( "UniProtKB:Q9Z0D9") "C-X3-C CKR-1 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:Q9Z0D9") "CX3CR1 (mouse)") -AnnotationAssertion(Annotation( "UniProtKB:Q9Z0D9") "fractalkine receptor (mouse)") -AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mCX3CR1") -AnnotationAssertion( "protein") -AnnotationAssertion(Annotation( "UniProtKB:Q9Z0D9") Annotation( ) "Cx3cr1") -AnnotationAssertion( "PR:Q9Z0D9") -AnnotationAssertion(rdfs:comment "Category=organism-gene.") -AnnotationAssertion(rdfs:label "CX3C chemokine receptor 1 (mouse)") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (system) AnnotationAssertion( "A material entity consisting of multiple components that are causally integrated.") @@ -151031,24 +35351,13 @@ AnnotationAssertion(rdfs:label "syst SubClassOf( ) -EquivalentClasses(ObjectIntersectionOf( ObjectSomeValuesFrom( )) ObjectIntersectionOf( ObjectMinCardinality(2 ))) -EquivalentClasses(ObjectIntersectionOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -EquivalentClasses(ObjectIntersectionOf( ObjectSomeValuesFrom( )) ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -EquivalentClasses(ObjectIntersectionOf( ObjectSomeValuesFrom( )) ObjectIntersectionOf( ObjectExactCardinality(2 ))) -EquivalentClasses(ObjectIntersectionOf( ObjectSomeValuesFrom( )) ObjectIntersectionOf( ObjectExactCardinality(1 ))) -EquivalentClasses(ObjectIntersectionOf( ObjectSomeValuesFrom( )) ObjectIntersectionOf( ObjectMinCardinality(2 ))) -SubClassOf(ObjectIntersectionOf( ObjectSomeValuesFrom( )) ObjectSomeValuesFrom( )) -SubClassOf(ObjectIntersectionOf( ObjectSomeValuesFrom( )) ObjectSomeValuesFrom( )) SubClassOf(ObjectIntersectionOf( ObjectSomeValuesFrom( )) ) SubClassOf(ObjectIntersectionOf( ObjectSomeValuesFrom( )) ) SubClassOf(ObjectIntersectionOf( ObjectSomeValuesFrom( )) ) SubClassOf(Annotation( ) ObjectIntersectionOf( ObjectSomeValuesFrom( )) ObjectSomeValuesFrom( )) -SubClassOf(ObjectSomeValuesFrom( ) ) SubClassOf(ObjectSomeValuesFrom( ) ObjectUnionOf(ObjectSomeValuesFrom( ObjectSomeValuesFrom( )) ObjectSomeValuesFrom( ObjectSomeValuesFrom( ObjectSomeValuesFrom( ))))) DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )) DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )) -DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )) -DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )) SubObjectPropertyOf(ObjectPropertyChain( ) ) SubObjectPropertyOf(ObjectPropertyChain( ) ) SubObjectPropertyOf(ObjectPropertyChain( ) ) @@ -151076,8 +35385,6 @@ SubObjectPropertyOf(ObjectPropertyChain( ) ) SubObjectPropertyOf(ObjectPropertyChain( ) ) SubObjectPropertyOf(ObjectPropertyChain( ) ) -SubObjectPropertyOf(ObjectPropertyChain( ) ) -SubObjectPropertyOf(ObjectPropertyChain( ) ) SubObjectPropertyOf(ObjectPropertyChain( ) ) SubObjectPropertyOf(ObjectPropertyChain( ) ) SubObjectPropertyOf(ObjectPropertyChain( ) ) @@ -151130,8 +35437,6 @@ SubObjectPropertyOf(ObjectPropertyChain( ) ) SubObjectPropertyOf(ObjectPropertyChain( ) ) SubObjectPropertyOf(ObjectPropertyChain( ) ) -SubObjectPropertyOf(ObjectPropertyChain( ) ) -SubObjectPropertyOf(ObjectPropertyChain( ) ) SubObjectPropertyOf(Annotation( "true"^^xsd:boolean) ObjectPropertyChain( ) ) SubObjectPropertyOf(ObjectPropertyChain( ) ) SubObjectPropertyOf(ObjectPropertyChain( ) ) @@ -151181,6 +35486,9 @@ DLSafeRule(Body(ObjectPropertyAtom( V DLSafeRule(Body(ObjectPropertyAtom( Variable() Variable()) ObjectPropertyAtom( Variable() Variable()))Head(ObjectPropertyAtom( Variable() Variable()))) DLSafeRule(Body(ObjectPropertyAtom( Variable() Variable()) ObjectPropertyAtom( Variable() Variable()))Head(ObjectPropertyAtom( Variable() Variable()))) DLSafeRule(Body(ObjectPropertyAtom( Variable() Variable()) ObjectPropertyAtom( Variable() Variable()))Head(ObjectPropertyAtom( Variable() Variable()))) +AnnotationAssertion( "terms merged"@en) +AnnotationAssertion( "An editor note should explain what were the merged terms and the reason for the merge."@en) +AnnotationAssertion(rdfs:label "terms merged"@en) AnnotationAssertion(Annotation( ) "researcher") AnnotationAssertion(Annotation( ) rdfs:label "Nicole Vasilevsky") AnnotationAssertion(Annotation( ) "German-Moroccan paleontologist and anatomist") diff --git a/src/ontology/imports/omo_terms.txt b/src/ontology/imports/omo_terms.txt new file mode 100644 index 0000000000..d3f1423d84 --- /dev/null +++ b/src/ontology/imports/omo_terms.txt @@ -0,0 +1,3 @@ +OMO:0003004 +OMO:0003000 + diff --git a/src/ontology/uberon-odk.yaml b/src/ontology/uberon-odk.yaml index 74fe8513f7..e349f1cfcd 100644 --- a/src/ontology/uberon-odk.yaml +++ b/src/ontology/uberon-odk.yaml @@ -69,6 +69,8 @@ import_group: mirror_from: https://w3id.org/orcidio/orcidio.owl base_iris: - https://orcid.org/ + - id: omo + module_type: mirror subset_group: products: - id: appendicular-minimal From 3240ea79d864a84510e0fac346b4ea9298aa8858 Mon Sep 17 00:00:00 2001 From: Anita Caron Date: Wed, 25 Oct 2023 16:57:29 +0100 Subject: [PATCH 2/2] update import with OMO:0003011 --- src/ontology/imports/merged_import.owl | 89759 ++++++++++++++++++++++- src/ontology/imports/omo_terms.txt | 2 + 2 files changed, 89201 insertions(+), 560 deletions(-) diff --git a/src/ontology/imports/merged_import.owl b/src/ontology/imports/merged_import.owl index d843adc2be..4a9e67fde1 100644 --- a/src/ontology/imports/merged_import.owl +++ b/src/ontology/imports/merged_import.owl @@ -7,9 +7,19 @@ Prefix(rdfs:=) Ontology( - -Annotation(owl:versionInfo "2023-09-18") - + +Annotation(owl:versionInfo "2023-10-25") + +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -21,59 +31,127 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -90,10 +168,16 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -104,6 +188,9 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -113,17 +200,25 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -134,47 +229,93 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -188,16 +329,24 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -205,53 +354,87 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -268,34 +451,70 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -308,21 +527,37 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -330,12 +565,26 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -344,38 +593,87 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -385,18 +683,41 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -404,40 +725,77 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -446,32 +804,53 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -493,25 +872,32 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -519,27 +905,32 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -550,11 +941,16 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -566,6 +962,7 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -576,11 +973,15 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -588,59 +989,86 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -656,10 +1084,12 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -672,18 +1102,27 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -694,135 +1133,335 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -834,23 +1473,141 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -859,6 +1616,7 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -866,12 +1624,76 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -882,6 +1704,7 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -891,46 +1714,462 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -947,83 +2186,483 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -1040,10 +2679,257 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -1057,80 +2943,343 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -1150,37 +3299,142 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -1192,62 +3446,519 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -1255,223 +3966,1904 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) -Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -1490,39 +5882,230 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -1547,148 +6130,1930 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -1734,6 +8099,9 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -1847,17 +8215,398 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -2327,7 +9076,6 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) -Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -2383,15 +9131,334 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -2401,6 +9468,8 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -2412,7 +9481,11 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -2919,6 +9992,7 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -2927,6 +10001,9 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -2939,6 +10016,8 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -2968,35 +10047,54 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -3011,10 +10109,14 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -3022,38 +10124,367 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -4335,6 +11766,7 @@ Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) +Declaration(Class()) Declaration(Class()) Declaration(Class()) Declaration(Class()) @@ -4383,6 +11815,11 @@ Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) +Declaration(ObjectProperty()) +Declaration(ObjectProperty()) +Declaration(ObjectProperty()) +Declaration(ObjectProperty()) +Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) @@ -4408,6 +11845,7 @@ Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) +Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) @@ -4440,6 +11878,7 @@ Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) +Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) @@ -4473,11 +11912,16 @@ Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) +Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) +Declaration(ObjectProperty()) +Declaration(ObjectProperty()) +Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) +Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) @@ -4486,15 +11930,25 @@ Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) +Declaration(ObjectProperty()) Declaration(ObjectProperty()) +Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) +Declaration(ObjectProperty()) +Declaration(ObjectProperty()) +Declaration(ObjectProperty()) +Declaration(ObjectProperty()) +Declaration(ObjectProperty()) +Declaration(ObjectProperty()) +Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) +Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) @@ -4557,6 +12011,7 @@ Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) +Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) @@ -4567,6 +12022,10 @@ Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) +Declaration(ObjectProperty()) +Declaration(ObjectProperty()) +Declaration(ObjectProperty()) +Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) @@ -4576,6 +12035,9 @@ Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) +Declaration(ObjectProperty()) +Declaration(ObjectProperty()) +Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) @@ -4584,10 +12046,16 @@ Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) +Declaration(ObjectProperty()) +Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) +Declaration(ObjectProperty()) +Declaration(ObjectProperty()) Declaration(ObjectProperty()) +Declaration(ObjectProperty()) +Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) @@ -4601,10 +12069,30 @@ Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) +Declaration(ObjectProperty()) Declaration(ObjectProperty()) Declaration(ObjectProperty()) +Declaration(NamedIndividual()) +Declaration(NamedIndividual()) +Declaration(NamedIndividual()) +Declaration(NamedIndividual()) +Declaration(NamedIndividual()) +Declaration(NamedIndividual()) +Declaration(NamedIndividual()) +Declaration(NamedIndividual()) +Declaration(NamedIndividual()) +Declaration(NamedIndividual()) +Declaration(NamedIndividual()) +Declaration(NamedIndividual()) +Declaration(NamedIndividual()) +Declaration(NamedIndividual()) +Declaration(NamedIndividual()) +Declaration(NamedIndividual()) +Declaration(NamedIndividual()) +Declaration(NamedIndividual()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) +Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) @@ -4630,6 +12118,7 @@ Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) +Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) @@ -4652,7 +12141,6 @@ Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) -Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) @@ -4667,8 +12155,6 @@ Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) -Declaration(AnnotationProperty()) -Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) @@ -4699,6 +12185,7 @@ Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) +Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) @@ -4714,7 +12201,6 @@ Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) -Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) @@ -4728,7 +12214,6 @@ Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) -Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) @@ -4759,6 +12244,8 @@ Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) Declaration(AnnotationProperty()) +Declaration(AnnotationProperty()) +Declaration(AnnotationProperty()) Declaration(AnnotationProperty(rdfs:comment)) Declaration(AnnotationProperty(rdfs:label)) Declaration(AnnotationProperty(rdfs:seeAlso)) @@ -4845,13 +12332,14 @@ AnnotationAssertion(rdfs:label "cur # Annotation Property: (term tracker item) -AnnotationAssertion( "IAO:0000233") -AnnotationAssertion( "external") -AnnotationAssertion( "term_tracker_item") -AnnotationAssertion( "true"^^xsd:boolean) -AnnotationAssertion( "true"^^xsd:boolean) -AnnotationAssertion( "term_tracker_item") -AnnotationAssertion(rdfs:label "term tracker item") +AnnotationAssertion( "term tracker item"@en) +AnnotationAssertion( "the URI for an OBI Terms ticket at sourceforge, such as https://sourceforge.net/p/obi/obi-terms/772/"@en) +AnnotationAssertion( ) +AnnotationAssertion( "An IRI or similar locator for a request or discussion of an ontology term."@en) +AnnotationAssertion( "Person: Jie Zheng, Chris Stoeckert, Alan Ruttenberg"@en) +AnnotationAssertion( "Person: Jie Zheng, Chris Stoeckert, Alan Ruttenberg"@en) +AnnotationAssertion(rdfs:comment "The 'tracker item' can associate a tracker with a specific ontology term."@en) +AnnotationAssertion(rdfs:label "term tracker item"@en) # Annotation Property: (expand assertion to) @@ -4867,13 +12355,10 @@ AnnotationAssertion(rdfs:label "exp # Annotation Property: (has ontology root term) -AnnotationAssertion( "IAO:0000700") -AnnotationAssertion( "external") -AnnotationAssertion( "has_ontology_root_term") -AnnotationAssertion( "true"^^xsd:boolean) -AnnotationAssertion( "true"^^xsd:boolean) -AnnotationAssertion( "has_ontology_root_term") -AnnotationAssertion(rdfs:label "has ontology root term") +AnnotationAssertion( "has ontology root term"@en) +AnnotationAssertion( "Ontology annotation property. Relates an ontology to a term that is a designated root term of the ontology. Display tools like OLS can use terms annotated with this property as the starting point for rendering the ontology class hierarchy. There can be more than one root."@en) +AnnotationAssertion( "Nicolas Matentzoglu"@en) +AnnotationAssertion(rdfs:label "has ontology root term"@en) AnnotationAssertion(rdfs:label "preferred_root") # Annotation Property: (scheduled for obsoletion on or after) @@ -4897,6 +12382,35 @@ AnnotationAssertion(rdfs:comment "A AnnotationAssertion(rdfs:label "term replaced by"@en) AnnotationAssertion(rdfs:label "term replaced by") +# Annotation Property: (abbreviation) + +AnnotationAssertion( "CHEBI:26523 (reactive oxygen species) has an exact synonym (ROS), which is of type OMO:0003000 (abbreviation)") +AnnotationAssertion( "A synonym type for describing abbreviations or initalisms") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( "2023-03-03"^^xsd:date) +AnnotationAssertion(rdfs:label "abbreviation") +SubAnnotationPropertyOf( ) + +# Annotation Property: (plural form) + +AnnotationAssertion( "CHEBI:23367 (molecular entity) has an exact synonym (molecular entities), which is of the type OMO:0003004 (plural form)") +AnnotationAssertion( "A synonym type for describing pluralization synonyms") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( "2023-03-03"^^xsd:date) +AnnotationAssertion(rdfs:label "plural form") +SubAnnotationPropertyOf( ) + +# Annotation Property: (latin term) + +AnnotationAssertion( "nasopharynx (UBERON:0001728) has the latin name \"pars nasalis pharyngis") +AnnotationAssertion( "A synonym type for describing Latin term synonyms.") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( "2023-10-12"^^xsd:date) +AnnotationAssertion(rdfs:label "latin term") + # Annotation Property: (never in taxon) AnnotationAssertion( "tooth SubClassOf 'never in taxon' value 'Aves'") @@ -5051,10 +12565,6 @@ SubAnnotationPropertyOf( ) -# Annotation Property: () - -SubAnnotationPropertyOf( ) - # Annotation Property: () SubAnnotationPropertyOf( ) @@ -5083,14 +12593,6 @@ SubAnnotationPropertyOf( ) -# Annotation Property: () - -SubAnnotationPropertyOf( ) - -# Annotation Property: () - -SubAnnotationPropertyOf( ) - # Annotation Property: () SubAnnotationPropertyOf( ) @@ -5207,6 +12709,10 @@ SubAnnotationPropertyOf( ) +# Annotation Property: () + +SubAnnotationPropertyOf( ) + # Annotation Property: () SubAnnotationPropertyOf( ) @@ -5836,6 +13342,39 @@ AnnotationAssertion( "preaxial to") TransitiveObjectProperty() +# Object Property: (has_not_completed) + +AnnotationAssertion(rdfs:label "has_not_completed") + +# Object Property: (lacks_part) + +AnnotationAssertion( "http://purl.obolibrary.org/obo/BFO_0000051 exactly 0 ?Y") +AnnotationAssertion(rdfs:label "lacks_part") + +# Object Property: (lacks_plasma_membrane_part) + +AnnotationAssertion( "http://purl.obolibrary.org/obo/BFO_0000051 exactly 0 (http://purl.obolibrary.org/obo/GO_0005886 and http://purl.obolibrary.org/obo/BFO_0000051 some ?Y)") +AnnotationAssertion(rdfs:label "lacks_plasma_membrane_part") + +# Object Property: (results in distribution of) + +AnnotationAssertion( "GOREL:0002003") +AnnotationAssertion( "external") +AnnotationAssertion( "results_in_distribution_of") +AnnotationAssertion( "results_in_distribution_of") +AnnotationAssertion(rdfs:label "results in distribution of") +AnnotationAssertion(rdfs:label "results_in_distribution_of") + +# Object Property: (results in fission of) + +AnnotationAssertion( "GOREL:0002004") +AnnotationAssertion( "external") +AnnotationAssertion( "results_in_fission_of") +AnnotationAssertion( "results_in_fission_of") +AnnotationAssertion(rdfs:label "results in fission of") +AnnotationAssertion(rdfs:label "results_in_fission_of") +SubObjectPropertyOf( ) + # Object Property: (characteristic of) AnnotationAssertion( "inheres in"@en) @@ -6181,6 +13720,16 @@ SubObjectPropertyOf( ) ObjectPropertyRange( ) +# Object Property: (occurs across) + +AnnotationAssertion( "A relationship between a process and a barrier, where the process occurs in a region spanning the barrier. For cellular processes the barrier is typically a membrane. Examples include transport across a membrane and membrane depolarization.") +AnnotationAssertion( ) +AnnotationAssertion( "2017-07-20T17:19:37Z"^^xsd:dateTime) +AnnotationAssertion( "RO:0002021") +AnnotationAssertion( "occurs_across") +AnnotationAssertion(rdfs:label "occurs across") +SubObjectPropertyOf( ) + # Object Property: (directly regulated by) AnnotationAssertion( ) @@ -6633,6 +14182,21 @@ SubObjectPropertyOf( ) TransitiveObjectProperty() +# Object Property: (expressed in) + +AnnotationAssertion( "'neural crest cell' SubClassOf expresses some 'Wnt1 gene'") +AnnotationAssertion( ) +AnnotationAssertion( "x expressed in y if and only if there is a gene expression process (GO:0010467) that occurs in y, and one of the following holds: (i) x is a gene, and x is transcribed into a transcript as part of the gene expression process (ii) x is a transcript, and the transcription of x is part of the gene expression process (iii) x is a mature gene product such as a protein, and x was translated or otherwise processes from a transcript that was transcribed as part of this gene expression process") +AnnotationAssertion( ) +AnnotationAssertion( "RO:0002206") +AnnotationAssertion( "expressed_in") +AnnotationAssertion(rdfs:label "expressed in"@en) +SubObjectPropertyOf( ) +InverseObjectProperties( ) +ObjectPropertyDomain( ) +ObjectPropertyDomain( ObjectUnionOf( )) +ObjectPropertyRange( ) + # Object Property: (directly develops from) AnnotationAssertion( ) @@ -7113,6 +14677,16 @@ AnnotationAssertion( "part of developmental precursor of"@en) SubObjectPropertyOf( ) +# Object Property: (expresses) + +AnnotationAssertion( ) +AnnotationAssertion( "y expresses x if and only if there is a gene expression process (GO:0010467) that occurs in y, and one of the following holds: (i) x is a gene, and x is transcribed into a transcript as part of the gene expression process (ii) x is a transcript, and x was transcribed from a gene as part of the gene expression process (iii) x is a mature gene product (protein or RNA), and x was translated or otherwise processed from a transcript that was transcribed as part of the gene expression process.") +AnnotationAssertion( ) +AnnotationAssertion( "RO:0002292") +AnnotationAssertion( "expresses") +AnnotationAssertion(rdfs:label "expresses"@en) +SubObjectPropertyOf( ) + # Object Property: (results in developmental progression of) AnnotationAssertion( ) @@ -7151,14 +14725,11 @@ AnnotationAssertion( ) AnnotationAssertion( "GOC:mtg_berkeley_2013") AnnotationAssertion( "RO:0002297") -AnnotationAssertion( "external") -AnnotationAssertion( "results_in_formation_of") AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( "results_in_formation_of") AnnotationAssertion(rdfs:label "results in formation of"@en) -AnnotationAssertion(rdfs:label "results in formation of") SubObjectPropertyOf( ) SubObjectPropertyOf( ) InverseObjectProperties( ) @@ -7172,14 +14743,11 @@ AnnotationAssertion( ) AnnotationAssertion( "GOC:mtg_berkeley_2013") AnnotationAssertion( "RO:0002298") -AnnotationAssertion( "external") -AnnotationAssertion( "results_in_morphogenesis_of") AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( "results_in_morphogenesis_of") AnnotationAssertion(rdfs:label "results in morphogenesis of"@en) -AnnotationAssertion(rdfs:label "results in morphogenesis of") SubObjectPropertyOf( ) SubObjectPropertyOf( ) @@ -7192,14 +14760,11 @@ AnnotationAssertion( ) AnnotationAssertion( "GOC:mtg_berkeley_2013") AnnotationAssertion( "RO:0002299") -AnnotationAssertion( "external") -AnnotationAssertion( "results_in_maturation_of") AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( "results_in_maturation_of") AnnotationAssertion(rdfs:label "results in maturation of"@en) -AnnotationAssertion(rdfs:label "results in maturation of") SubObjectPropertyOf( ) SubObjectPropertyOf( ) @@ -7253,14 +14818,11 @@ AnnotationAssertion( ) AnnotationAssertion( "GOC:mtg_berkeley_2013") AnnotationAssertion( "RO:0002315") -AnnotationAssertion( "external") -AnnotationAssertion( "results_in_acquisition_of_features_of") AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( "results_in_acquisition_of_features_of") AnnotationAssertion(rdfs:label "results in acquisition of features of"@en) -AnnotationAssertion(rdfs:label "results in acquisition of features of") SubObjectPropertyOf( ) SubObjectPropertyOf( ) ObjectPropertyRange( ) @@ -7353,6 +14915,17 @@ AnnotationAssertion( "part of structure that is capable of"@en) SubObjectPropertyOf( ) +# Object Property: (genomically related to) + +AnnotationAssertion( "holds between two entities when some genome-level process such as gene expression is involved. This includes transcriptional, spliceosomal events. These relations can be used between either macromolecule entities (such as regions of nucleic acid) or between their abstract informational counterparts.") +AnnotationAssertion( ) +AnnotationAssertion( "Do not use this relation directly. It is intended as a grouping for a diverse set of relations, all involving the genome of an organism") +AnnotationAssertion( "RO:0002330") +AnnotationAssertion( "genomically_related_to") +AnnotationAssertion(rdfs:label "genomically related to"@en) +ObjectPropertyDomain( ) +ObjectPropertyRange( ) + # Object Property: (involved in) AnnotationAssertion( "c involved_in p if and only if c enables some process p', and p' is part of p") @@ -7374,11 +14947,8 @@ AnnotationAssertion( ) AnnotationAssertion( "regulates levels of (process to entity)") AnnotationAssertion( "RO:0002332") -AnnotationAssertion( "external") -AnnotationAssertion( "regulates_levels_of") AnnotationAssertion( "regulates_levels_of") AnnotationAssertion(rdfs:label "regulates levels of"@en) -AnnotationAssertion(rdfs:label "regulates levels of") SubObjectPropertyOf( ) ObjectPropertyDomain( ) ObjectPropertyRange( ) @@ -7445,14 +15015,11 @@ ObjectPropertyRange( "This relationship holds between p and l when p is a transport or localization process in which the outcome is to move some cargo c from some initial location l to some destination.") AnnotationAssertion( ) AnnotationAssertion( "RO:0002338") -AnnotationAssertion( "external") -AnnotationAssertion( "has_target_start_location") AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( "has_target_start_location") AnnotationAssertion(rdfs:label "has target start location"@en) -AnnotationAssertion(rdfs:label "has target start location") SubObjectPropertyOf( ) # Object Property: (has target end location) @@ -7460,14 +15027,11 @@ SubObjectPropertyOf( "This relationship holds between p and l when p is a transport or localization process in which the outcome is to move some cargo c from a an initial location to some destination l.") AnnotationAssertion( ) AnnotationAssertion( "RO:0002339") -AnnotationAssertion( "external") -AnnotationAssertion( "has_target_end_location") AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( "has_target_end_location") AnnotationAssertion(rdfs:label "has target end location"@en) -AnnotationAssertion(rdfs:label "has target end location") SubObjectPropertyOf( ) # Object Property: (results in transport along) @@ -7475,11 +15039,8 @@ SubObjectPropertyOf( "Holds between p and l when p is a transportation or localization process and the outcome of this process is to move c from one location to another, and the route taken by c follows a path that is aligned_with l ") AnnotationAssertion( ) AnnotationAssertion( "RO:0002341") -AnnotationAssertion( "external") -AnnotationAssertion( "results_in_transport_along") AnnotationAssertion( "results_in_transport_along") AnnotationAssertion(rdfs:label "results in transport along"@en) -AnnotationAssertion(rdfs:label "results in transport along") SubObjectPropertyOf( ) # Object Property: (results in transport across) @@ -7487,12 +15048,9 @@ SubObjectPropertyOf( "Holds between p and m when p is a transportation or localization process and the outcome of this process is to move c from one location to another, and the route taken by c follows a path that crosses m.") AnnotationAssertion( ) AnnotationAssertion( "RO:0002342") -AnnotationAssertion( "external") -AnnotationAssertion( "results_in_transport_across") AnnotationAssertion( ) AnnotationAssertion( "results_in_transport_across") AnnotationAssertion(rdfs:label "results in transport across"@en) -AnnotationAssertion(rdfs:label "results in transport across") SubObjectPropertyOf( ) SubObjectPropertyOf( ) @@ -7501,11 +15059,8 @@ SubObjectPropertyOf( "'pollen tube growth' results_in growth_of some 'pollen tube'") AnnotationAssertion( ) AnnotationAssertion( "RO:0002343") -AnnotationAssertion( "external") -AnnotationAssertion( "results_in_growth_of") AnnotationAssertion( "results_in_growth_of") AnnotationAssertion(rdfs:label "results in growth of"@en) -AnnotationAssertion(rdfs:label "results in growth of") SubObjectPropertyOf( ) SubObjectPropertyOf( ) @@ -7514,11 +15069,8 @@ SubObjectPropertyOf( "'mitochondrial transport' results_in_transport_to_from_or_in some mitochondrion (GO:0005739)") AnnotationAssertion( ) AnnotationAssertion( "RO:0002344") -AnnotationAssertion( "external") -AnnotationAssertion( "results_in_transport_to_from_or_in") AnnotationAssertion( "results_in_transport_to_from_or_in") AnnotationAssertion(rdfs:label "results in transport to from or in"@en) -AnnotationAssertion(rdfs:label "results in transport to from or in") SubObjectPropertyOf( ) # Object Property: (member of) @@ -7570,6 +15122,14 @@ AnnotationAssertion(rdfs:label "outp SubObjectPropertyOf( ) SubObjectPropertyOf( ) +# Object Property: (formed as result of) + +AnnotationAssertion( ) +AnnotationAssertion( "RO:0002354") +AnnotationAssertion( "formed_as_result_of") +AnnotationAssertion(rdfs:label "formed as result of"@en) +SubObjectPropertyOf( ) + # Object Property: (attached to) AnnotationAssertion( "a is attached to b if and only if a and b are discrete objects or object parts, and there are physical connections between a and b such that a force pulling a will move b, or a force pulling b will move a") @@ -8322,8 +15882,6 @@ AnnotationAssertion( ) AnnotationAssertion( "") AnnotationAssertion( "RO:0002565") -AnnotationAssertion( "external") -AnnotationAssertion( "results_in_movement_of") AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( ) @@ -8467,8 +16025,6 @@ SubObjectPropertyOf( (results in assembly of) AnnotationAssertion( "RO:0002588") -AnnotationAssertion( "external") -AnnotationAssertion( "results_in_assembly_of") AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( ) @@ -8480,8 +16036,6 @@ SubObjectPropertyOf( (results in disassembly of) AnnotationAssertion( "RO:0002590") -AnnotationAssertion( "external") -AnnotationAssertion( "results_in_disassembly_of") AnnotationAssertion( "results_in_disassembly_of") AnnotationAssertion(rdfs:label "results in disassembly of") SubObjectPropertyOf( ) @@ -8491,11 +16045,8 @@ SubObjectPropertyOf( "p results in organization of c iff p results in the assembly, arrangement of constituent parts, or disassembly of c") AnnotationAssertion( "RO:0002592") -AnnotationAssertion( "external") -AnnotationAssertion( "results_in_organization_of") AnnotationAssertion( "results_in_organization_of") AnnotationAssertion(rdfs:label "results in organization of") -SubObjectPropertyOf( ) SubObjectPropertyOf( ) # Object Property: (causal relation between material entity and a process) @@ -8613,8 +16164,6 @@ AnnotationAssertion( ) AnnotationAssertion( "2018-12-13T11:26:17Z"^^xsd:dateTime) AnnotationAssertion( "RO:0004007") -AnnotationAssertion( "external") -AnnotationAssertion( "has_primary_input_or_output") AnnotationAssertion( ) AnnotationAssertion( "has_primary_input_or_output") AnnotationAssertion(rdfs:label "has primary input or output") @@ -8626,8 +16175,6 @@ AnnotationAssertion(Annotation( ) AnnotationAssertion( "2018-12-13T11:26:32Z"^^xsd:dateTime) AnnotationAssertion( "RO:0004008") -AnnotationAssertion( "external") -AnnotationAssertion( "has_primary_output") AnnotationAssertion( ) AnnotationAssertion( "has_primary_output") AnnotationAssertion(rdfs:label "has primary output") @@ -8640,8 +16187,6 @@ AnnotationAssertion(Annotation( ) AnnotationAssertion( "2018-12-13T11:26:56Z"^^xsd:dateTime) AnnotationAssertion( "RO:0004009") -AnnotationAssertion( "external") -AnnotationAssertion( "has_primary_input") AnnotationAssertion( ) AnnotationAssertion( "has_primary_input") AnnotationAssertion(rdfs:label "has primary input") @@ -8749,14 +16294,11 @@ AnnotationAssertion( ) AnnotationAssertion( "2020-06-08T17:21:33Z"^^xsd:dateTime) AnnotationAssertion( "RO:0012003") -AnnotationAssertion( "external") -AnnotationAssertion( "acts_on_population_of") AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( "acts_on_population_of") AnnotationAssertion(rdfs:label "acts on population of"@en) -AnnotationAssertion(rdfs:label "acts on population of") SubObjectPropertyOf( ) # Object Property: (results in fusion of) @@ -8764,14 +16306,11 @@ SubObjectPropertyOf( ) AnnotationAssertion( "2021-02-26T07:28:29Z"^^xsd:dateTime) AnnotationAssertion( "RO:0012008") -AnnotationAssertion( "external") -AnnotationAssertion( "results_in_fusion_of") AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( "results_in_fusion_of") AnnotationAssertion(rdfs:label "results in fusion of"@en) -AnnotationAssertion(rdfs:label "results in fusion of") SubObjectPropertyOf( ) # Object Property: (indirectly causally upstream of) @@ -8806,6 +16345,26 @@ AnnotationAssertion( "has synaptic IO in region"@en) SubObjectPropertyOf( ) +# Object Property: (different in magnitude relative to) + +AnnotationAssertion(Annotation( "https://orcid.org/0000-0002-6601-2165") "q1 different_in_magnitude_relative_to q2 if and only if magnitude(q1) NOT =~ magnitude(q2). Here, magnitude(q) is a function that maps a quality to a unit-invariant scale.") +AnnotationAssertion( "RO:0015006") +AnnotationAssertion( "different_in_magnitude_relative_to") +AnnotationAssertion(rdfs:label "different in magnitude relative to") +ObjectPropertyDomain( ) +ObjectPropertyRange( ) + +# Object Property: (increased in magnitude relative to) + +AnnotationAssertion(Annotation( "https://orcid.org/0000-0002-6601-2165") "q1 increased_in_magnitude_relative_to q2 if and only if magnitude(q1) > magnitude(q2). Here, magnitude(q) is a function that maps a quality to a unit-invariant scale.") +AnnotationAssertion( "RO:0015007") +AnnotationAssertion( "increased_in_magnitude_relative_to") +AnnotationAssertion(rdfs:comment "This relation is used to determine the 'directionality' of relative qualities such as 'increased strength', relative to the parent type, 'strength'.") +AnnotationAssertion(rdfs:label "increased in magnitude relative to") +SubObjectPropertyOf( ) +ObjectPropertyDomain( ) +ObjectPropertyRange( ) + # Object Property: (has cross section) AnnotationAssertion(Annotation( "https://orcid.org/0000-0002-6601-2165") "s3 has_cross_section s3 if and only if : there exists some 2d plane that intersects the bearer of s3, and the impression of s3 upon that plane has shape quality s2.") @@ -8814,6 +16373,30 @@ AnnotationAssertion( "Example: a spherical object has the quality of being spherical, and the spherical quality has_cross_section round.") AnnotationAssertion(rdfs:label "has cross section") +# Object Property: (has high plasma membrane amount) + +AnnotationAssertion( "'Ly-76 high positive erythrocyte' equivalent to 'enucleate erythrocyte' and (has_high_plasma_membrane_amount some 'lymphocyte antigen 76 (mouse)')") +AnnotationAssertion(Annotation( "PMID:19243617") "A relation between a cell and molecule or complex such that every instance of the cell has a high number of instances of that molecule expressed on the cell surface.") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( "RO:0015015") +AnnotationAssertion( "has_high_plasma_membrane_amount") +AnnotationAssertion(rdfs:label "has high plasma membrane amount") +SubObjectPropertyOf( ) +ObjectPropertyDomain( ) + +# Object Property: (has low plasma membrane amount) + +AnnotationAssertion( "'DN2b thymocyte' equivalent to 'DN2 thymocyte' and (has_low_plasma_membrane_amount some 'mast/stem cell growth factor receptor')") +AnnotationAssertion(Annotation( "PMID:19243617") "A relation between a cell and molecule or complex such that every instance of the cell has a low number of instances of that molecule expressed on the cell surface.") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( "RO:0015016") +AnnotationAssertion( "has_low_plasma_membrane_amount") +AnnotationAssertion(rdfs:label "has low plasma membrane amount") +SubObjectPropertyOf( ) +ObjectPropertyDomain( ) + # Object Property: (device utilizes material) AnnotationAssertion( "A diagnostic testing device utilizes a specimen.") @@ -8871,6 +16454,10 @@ SubObjectPropertyOf( "by_means"@en) +# Object Property: (has_participant) + +AnnotationAssertion(rdfs:label "has_participant"@en) + ############################ @@ -8959,6 +16546,7 @@ AnnotationAssertion(rdfs:label "ind SubClassOf( ) SubClassOf( ObjectAllValuesFrom( )) DisjointClasses( ) +DisjointClasses( ) # Class: (spatial region) @@ -9073,6 +16661,7 @@ AnnotationAssertion(rdfs:isDefinedBy "specifically dependent continuant"@en) SubClassOf( ) SubClassOf( ObjectAllValuesFrom( )) +DisjointClasses( ) # Class: (role) @@ -9093,6 +16682,21 @@ AnnotationAssertion(rdfs:isDefinedBy "role"@en) SubClassOf( ) +# Class: (generically dependent continuant) + +AnnotationAssertion( "gdc") +AnnotationAssertion( "GenericallyDependentContinuant") +AnnotationAssertion( "The entries in your database are patterns instantiated as quality instances in your hard drive. The database itself is an aggregate of such patterns. When you create the database you create a particular instance of the generically dependent continuant type database. Each entry in the database is an instance of the generically dependent continuant type IAO: information content entity."@en) +AnnotationAssertion( "the pdf file on your laptop, the pdf file that is a copy thereof on my laptop"@en) +AnnotationAssertion( "the sequence of this protein molecule; the sequence that is a copy thereof in that protein molecule."@en) +AnnotationAssertion(Annotation( ) "b is a generically dependent continuant = Def. b is a continuant that g-depends_on one or more other entities. (axiom label in BFO2 Reference: [074-001])"@en) +AnnotationAssertion(Annotation( ) "(iff (GenericallyDependentContinuant a) (and (Continuant a) (exists (b t) (genericallyDependsOnAt a b t)))) // axiom label in BFO2 CLIF: [074-001] ") +AnnotationAssertion(rdfs:comment "A continuant that is dependent on one or other independent continuant bearers. For every instance of A requires some instance of (an independent continuant type) B but which instance of B serves can change from time to time."@en) +AnnotationAssertion(rdfs:isDefinedBy ) +AnnotationAssertion(rdfs:label "generically dependent continuant"@en) +SubClassOf( ) +SubClassOf( ObjectAllValuesFrom( )) + # Class: (function) AnnotationAssertion( "function") @@ -9182,6 +16786,38 @@ AnnotationAssertion( "electron") SubClassOf( ) +# Class: (steroid aldehyde) + +AnnotationAssertion( "Any steroid substituted by a formyl group.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "steroid aldehydes") +AnnotationAssertion( "CHEBI:131565") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "steroid aldehyde") +SubClassOf( ) +SubClassOf( ) + +# Class: (Mycoplasma genitalium metabolite) + +AnnotationAssertion( "Any bacterial metabolite produced during a metabolic reaction in Mycoplasma genitalium.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "Mycoplasma genitalium metabolites") +AnnotationAssertion( "CHEBI:131604") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "Mycoplasma genitalium metabolite") +SubClassOf( ) + +# Class: (C19-steroid) + +AnnotationAssertion( "A steroid compound with a structure based on a 19-carbon (androstane) skeleton.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "C19-steroids") +AnnotationAssertion( "CHEBI:131621") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "C19-steroid") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (dicarboxylic acids and O-substituted derivatives) AnnotationAssertion( "A class of carbonyl compound encompassing dicarboxylic acids and any derivatives obtained by substitution of either one or both of the carboxy hydrogens.") @@ -9207,6 +16843,33 @@ SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (3-oxo-Delta(4)-steroid group) + +AnnotationAssertion( "An organic group derived from any 3-oxo-Delta(4)-steroid.") +AnnotationAssertion( "0") +AnnotationAssertion( "C6H6O") +AnnotationAssertion( "94.111") +AnnotationAssertion( "94.04186") +AnnotationAssertion( "C1=C(C*)*C(CC1=O)*") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "UniProt") "a 3-oxo-Delta4-steroid group") +AnnotationAssertion( "CHEBI:136849") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "3-oxo-Delta(4)-steroid group") +SubClassOf( ) + +# Class: (5beta steroid) + +AnnotationAssertion( "Any steroid that has beta-configuration at position 5.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "5beta steroids") +AnnotationAssertion(Annotation( "ChEBI") "5beta-steroid") +AnnotationAssertion(Annotation( "ChEBI") "5beta-steroids") +AnnotationAssertion( "CHEBI:136889") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "5beta steroid") +SubClassOf( ) + # Class: (inorganic acid) AnnotationAssertion( "A Bronsted acid derived from one or more inorganic compounds. Inorganic acids (also known as mineral acids) form hydrons and conjugate base ions when dissolved in water.") @@ -9220,6 +16883,17 @@ AnnotationAssertion( "inorganic acid") SubClassOf( ) +# Class: (bile acids) + +AnnotationAssertion( "Any member of a group of hydroxy steroids occuring in bile, where they are present as the sodium salts of their amides with glycine or taurine. In mammals bile acids almost invariably have 5beta-configuration, while in lower vertebrates, some bile acids, known as allo-bile acids, have 5alpha-configuration.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion( "CHEBI:138366") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "bile acids") +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + # Class: (apoprotein) AnnotationAssertion( "An apoprotein is a protein devoid of its characteristic prosthetic group or metal.") @@ -9287,6 +16961,45 @@ AnnotationAssertion(rdfs:label "car SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (alpha-hydroxy ketone) + +AnnotationAssertion( "An alpha-oxyketone that has a hydroxy group as the alpha-oxy moiety.") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:15326516") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:19908854") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:20382022") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:23295224") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "alpha-hydroxy ketones") +AnnotationAssertion(Annotation( "ChEBI") "alpha-hydroxy-ketone") +AnnotationAssertion(Annotation( "ChEBI") "alpha-hydroxy-ketones") +AnnotationAssertion(Annotation( "ChEBI") "alpha-hydroxyketone") +AnnotationAssertion(Annotation( "ChEBI") "alpha-hydroxyketones") +AnnotationAssertion( "CHEBI:139588") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "alpha-hydroxy ketone") +SubClassOf( ) +SubClassOf( ) + +# Class: (primary alpha-hydroxy ketone) + +AnnotationAssertion( "An alpha-hydroxy ketone in which the carbonyl group and the hydroxy group are linked by a -CH2 (methylene) group.") +AnnotationAssertion( "0") +AnnotationAssertion( "C2H3O2R") +AnnotationAssertion( "59.044") +AnnotationAssertion( "59.01330") +AnnotationAssertion( "*C(C(O)([H])[H])=O") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "primary alpha-hydroxy ketones") +AnnotationAssertion(Annotation( "ChEBI") "primary alpha-hydroxy-ketone") +AnnotationAssertion(Annotation( "ChEBI") "primary alpha-hydroxy-ketones") +AnnotationAssertion(Annotation( "ChEBI") "primary alpha-hydroxyketone") +AnnotationAssertion(Annotation( "ChEBI") "primary alpha-hydroxyketones") +AnnotationAssertion( "CHEBI:139590") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "primary alpha-hydroxy ketone") +SubClassOf( ) +SubClassOf( ) + # Class: (secondary carboxamide) AnnotationAssertion( "A carboxamide resulting from the formal condensation of a carboxylic acid with a primary amine; formula RC(=O)NHR(1).") @@ -9302,6 +17015,21 @@ AnnotationAssertion( "secondary carboxamide") SubClassOf( ) +# Class: (fatty acid 4:0) + +AnnotationAssertion( "Any saturated fatty acid containing 4 carbons.") +AnnotationAssertion( "0") +AnnotationAssertion( "CHO2R") +AnnotationAssertion( "45.017") +AnnotationAssertion( "44.99765") +AnnotationAssertion( "*C(O)=O") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion( "CHEBI:140601") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "fatty acid 4:0") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (24G7 epitope) AnnotationAssertion( "An antigenic epitope recognized by an anti-bilirubin monoclonal antibody designated 24G7. A substructure of bilirubin IXalpha, it is the region containing the oxo group at C-1, the methyl group at C-2, C-(4, 5, 6, 9), and N-21 and -22.") @@ -9317,6 +17045,48 @@ AnnotationAssertion(rdfs:label "24 SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (purines D-ribonucleoside) + +AnnotationAssertion( "A purine ribonucleoside that is a purine derivative attached to a beta-D-ribofuranosyl residue at position 9 via a glycosidic (N-glycosyl) linkage.") +AnnotationAssertion( "0") +AnnotationAssertion( "C10H11N4O4R2") +AnnotationAssertion( "251.219") +AnnotationAssertion( "251.07803") +AnnotationAssertion( "C1(=*)NC(=NC2=C1N=CN2[C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)*") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "UniProt") "a purine D-ribonucleoside") +AnnotationAssertion( "CHEBI:142355") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "purines D-ribonucleoside") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (glutamate(1-)) + +AnnotationAssertion( "An alpha-amino-acid anion that is the conjugate base of glutamic acid, having anionic carboxy groups and a cationic amino group") +AnnotationAssertion( "-1") +AnnotationAssertion( "C5H8NO4") +AnnotationAssertion( "InChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/p-1") +AnnotationAssertion( "WHUUTDBJXJRKMK-UHFFFAOYSA-M") +AnnotationAssertion( "146.12136") +AnnotationAssertion( "146.04588") +AnnotationAssertion( "[NH3+]C(CCC([O-])=O)C([O-])=O") +AnnotationAssertion(Annotation( "Gmelin") "Gmelin:327908") +AnnotationAssertion(Annotation( "JCBN") "glutamate(1-)") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "hydrogen glutamate") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "IUPAC") "2-ammoniopentanedioate") +AnnotationAssertion(Annotation( "UniProt") "glutamate") +AnnotationAssertion(Annotation( "JCBN") "glutamic acid monoanion") +AnnotationAssertion( "CHEBI:14321") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "glutamate(1-)") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (acceptor) AnnotationAssertion( "A molecular entity that can accept an electron, a pair of electrons, an atom or a group from another molecular entity.") @@ -9413,6 +17183,339 @@ SubClassOf( ObjectSomeValuesFrom( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (acetylcholine) + +AnnotationAssertion( "Actylcholine is an ester of acetic acid and choline, which acts as a neurotransmitter.") +AnnotationAssertion( "+1") +AnnotationAssertion( "C7H16NO2") +AnnotationAssertion( "InChI=1S/C7H16NO2/c1-7(9)10-6-5-8(2,3)4/h5-6H2,1-4H3/q+1") +AnnotationAssertion( "OIPILFWXSMYKGL-UHFFFAOYSA-N") +AnnotationAssertion( "146.20748") +AnnotationAssertion( "146.11756") +AnnotationAssertion( "CC(=O)OCC[N+](C)(C)C") +AnnotationAssertion( "CHEBI:12686") +AnnotationAssertion( "CHEBI:13715") +AnnotationAssertion( "CHEBI:22197") +AnnotationAssertion( "CHEBI:2416") +AnnotationAssertion( "CHEBI:40559") +AnnotationAssertion(Annotation( "ChemIDplus") "Beilstein:1764436") +AnnotationAssertion(Annotation( "ChemIDplus") "CAS:51-84-3") +AnnotationAssertion(Annotation( "KEGG COMPOUND") "CAS:51-84-3") +AnnotationAssertion( "DrugBank:DB03128") +AnnotationAssertion(Annotation( "DrugCentral") "Drug_Central:65") +AnnotationAssertion(Annotation( "Gmelin") "Gmelin:326108") +AnnotationAssertion( "KEGG:C01996") +AnnotationAssertion( "LINCS:LSM-5888") +AnnotationAssertion( "PDBeChem:ACH") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:14764638") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:15014918") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:15231705") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:15361288") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:18050502") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:18407448") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:19255787") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:20963497") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:21130809") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:21246223") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:21545631") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:21601579") +AnnotationAssertion( "Wikipedia:Acetylcholine") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "2-acetyloxy-N,N,N-trimethylethanaminium") +AnnotationAssertion(Annotation( "PDBeChem") "ACETYLCHOLINE") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Acetylcholine") +AnnotationAssertion(Annotation( "UniProt") "acetylcholine") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChemIDplus") "ACh") +AnnotationAssertion(Annotation( "ChEBI") "Azetylcholin") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "O-Acetylcholine") +AnnotationAssertion(Annotation( "ChemIDplus") "choline acetate") +AnnotationAssertion( "CHEBI:15355") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "acetylcholine") +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (acetic acid) + +AnnotationAssertion( "A simple monocarboxylic acid containing two carbons.") +AnnotationAssertion( "0") +AnnotationAssertion( "C2H4O2") +AnnotationAssertion( "InChI=1S/C2H4O2/c1-2(3)4/h1H3,(H,3,4)") +AnnotationAssertion( "QTBSBXVTEAMEQO-UHFFFAOYSA-N") +AnnotationAssertion( "60.05200") +AnnotationAssertion( "60.02113") +AnnotationAssertion( "CC(O)=O") +AnnotationAssertion( "CHEBI:22169") +AnnotationAssertion( "CHEBI:2387") +AnnotationAssertion( "CHEBI:40486") +AnnotationAssertion(Annotation( "Beilstein") "Beilstein:506007") +AnnotationAssertion(Annotation( "ChemIDplus") "CAS:64-19-7") +AnnotationAssertion(Annotation( "KEGG COMPOUND") "CAS:64-19-7") +AnnotationAssertion(Annotation( "NIST Chemistry WebBook") "CAS:64-19-7") +AnnotationAssertion(Annotation( "DrugCentral") "Drug_Central:4211") +AnnotationAssertion(Annotation( "Gmelin") "Gmelin:1380") +AnnotationAssertion( "HMDB:HMDB0000042") +AnnotationAssertion( "KEGG:C00033") +AnnotationAssertion( "KEGG:D00010") +AnnotationAssertion( "KNApSAcK:C00001176") +AnnotationAssertion(Annotation( "LIPID MAPS") "LIPID_MAPS_instance:LMFA01010002") +AnnotationAssertion( "MetaCyc:ACET") +AnnotationAssertion( "PDBeChem:ACT") +AnnotationAssertion( "PDBeChem:ACY") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:12005138") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:15107950") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:16630552") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:16774200") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:17190852") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:19416101") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:19469536") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:22153255") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:22173419") +AnnotationAssertion( "PPDB:1333") +AnnotationAssertion(Annotation( "Reaxys") "Reaxys:506007") +AnnotationAssertion( "Wikipedia:Acetic_acid") +AnnotationAssertion(Annotation( "PDBeChem") "ACETIC ACID") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Acetic acid") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "acetic acid") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "AcOH") +AnnotationAssertion(Annotation( "IUPAC") "CH3-COOH") +AnnotationAssertion(Annotation( "ChEBI") "CH3CO2H") +AnnotationAssertion(Annotation( "ChEBI") "E 260") +AnnotationAssertion(Annotation( "ChEBI") "E-260") +AnnotationAssertion(Annotation( "ChEBI") "E260") +AnnotationAssertion(Annotation( "ChEBI") "Essigsaeure") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Ethanoic acid") +AnnotationAssertion(Annotation( "ChemIDplus") "Ethylic acid") +AnnotationAssertion(Annotation( "ChEBI") "HOAc") +AnnotationAssertion(Annotation( "ChEBI") "INS No. 260") +AnnotationAssertion(Annotation( "ChEBI") "MeCO2H") +AnnotationAssertion(Annotation( "ChEBI") "MeCOOH") +AnnotationAssertion(Annotation( "ChemIDplus") "Methanecarboxylic acid") +AnnotationAssertion(Annotation( "ChemIDplus") "acide acetique") +AnnotationAssertion(Annotation( "ChEBI") "ethoic acid") +AnnotationAssertion( "CHEBI:15366") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "acetic acid") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (water) + +AnnotationAssertion( "An oxygen hydride consisting of an oxygen atom that is covalently bonded to two hydrogen atoms") +AnnotationAssertion( "0") +AnnotationAssertion( "H2O") +AnnotationAssertion( "InChI=1S/H2O/h1H2") +AnnotationAssertion( "XLYOFNOQVPJJNP-UHFFFAOYSA-N") +AnnotationAssertion( "18.01530") +AnnotationAssertion( "18.01056") +AnnotationAssertion( "[H]O[H]") +AnnotationAssertion( "CHEBI:10743") +AnnotationAssertion( "CHEBI:13352") +AnnotationAssertion( "CHEBI:27313") +AnnotationAssertion( "CHEBI:42043") +AnnotationAssertion( "CHEBI:42857") +AnnotationAssertion( "CHEBI:43228") +AnnotationAssertion( "CHEBI:44292") +AnnotationAssertion( "CHEBI:44701") +AnnotationAssertion( "CHEBI:44819") +AnnotationAssertion( "CHEBI:5585") +AnnotationAssertion(Annotation( "Beilstein") "Beilstein:3587155") +AnnotationAssertion(Annotation( "ChemIDplus") "CAS:7732-18-5") +AnnotationAssertion(Annotation( "KEGG COMPOUND") "CAS:7732-18-5") +AnnotationAssertion(Annotation( "NIST Chemistry WebBook") "CAS:7732-18-5") +AnnotationAssertion(Annotation( "Gmelin") "Gmelin:117") +AnnotationAssertion( "HMDB:HMDB0002111") +AnnotationAssertion( "KEGG:C00001") +AnnotationAssertion( "KEGG:D00001") +AnnotationAssertion( "MetaCyc:WATER") +AnnotationAssertion( "MolBase:1") +AnnotationAssertion( "PDBeChem:HOH") +AnnotationAssertion(Annotation( "Reaxys") "Reaxys:3587155") +AnnotationAssertion( "Wikipedia:Water") +AnnotationAssertion(Annotation( "PDBeChem") "WATER") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Water") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "oxidane") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "water") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "PDBeChem") "BOUND WATER") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "H2O") +AnnotationAssertion(Annotation( "UniProt") "H2O") +AnnotationAssertion(Annotation( "ChEBI") "HOH") +AnnotationAssertion(Annotation( "ChEBI") "Wasser") +AnnotationAssertion(Annotation( "IUPAC") "[OH2]") +AnnotationAssertion(Annotation( "ChEBI") "acqua") +AnnotationAssertion(Annotation( "ChEBI") "agua") +AnnotationAssertion(Annotation( "ChEBI") "aqua") +AnnotationAssertion(Annotation( "IUPAC") "dihydridooxygen") +AnnotationAssertion(Annotation( "IUPAC") "dihydrogen oxide") +AnnotationAssertion(Annotation( "ChEBI") "eau") +AnnotationAssertion(Annotation( "ChEBI") "hydrogen hydroxide") +AnnotationAssertion( "CHEBI:15377") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "water") +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (hydron) + +AnnotationAssertion( "The general name for the hydrogen nucleus, to be used without regard to the hydrogen nuclear mass (either for hydrogen in its natural abundance or where it is not desired to distinguish between the isotopes).") +AnnotationAssertion( "+1") +AnnotationAssertion( "H") +AnnotationAssertion( "InChI=1S/p+1") +AnnotationAssertion( "GPRLSGONYQIRFK-UHFFFAOYSA-N") +AnnotationAssertion( "1.00794") +AnnotationAssertion( "1.008") +AnnotationAssertion( "[H+]") +AnnotationAssertion( "CHEBI:10744") +AnnotationAssertion( "CHEBI:13357") +AnnotationAssertion( "CHEBI:5584") +AnnotationAssertion( "KEGG:C00080") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Hydron") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "hydrogen(1+)") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "hydron") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "UniProt") "H(+)") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "H+") +AnnotationAssertion( "CHEBI:15378") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "hydron") +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (dioxygen) + +AnnotationAssertion( "0") +AnnotationAssertion( "O2") +AnnotationAssertion( "InChI=1S/O2/c1-2") +AnnotationAssertion( "MYMOFIZGZYHOMD-UHFFFAOYSA-N") +AnnotationAssertion( "31.998") +AnnotationAssertion( "31.98983") +AnnotationAssertion( "O=O") +AnnotationAssertion( "CHEBI:10745") +AnnotationAssertion( "CHEBI:13416") +AnnotationAssertion( "CHEBI:23833") +AnnotationAssertion( "CHEBI:25366") +AnnotationAssertion( "CHEBI:30491") +AnnotationAssertion( "CHEBI:44742") +AnnotationAssertion( "CHEBI:7860") +AnnotationAssertion(Annotation( "ChemIDplus") "CAS:7782-44-7") +AnnotationAssertion(Annotation( "KEGG COMPOUND") "CAS:7782-44-7") +AnnotationAssertion(Annotation( "NIST Chemistry WebBook") "CAS:7782-44-7") +AnnotationAssertion(Annotation( "Gmelin") "Gmelin:485") +AnnotationAssertion( "HMDB:HMDB0001377") +AnnotationAssertion( "KEGG:C00007") +AnnotationAssertion( "KEGG:D00003") +AnnotationAssertion( "MetaCyc:OXYGEN-MOLECULE") +AnnotationAssertion( "MolBase:750") +AnnotationAssertion( "PDBeChem:OXY") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:10906528") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:16977326") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:18210929") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:18638417") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:19840863") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:7710549") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:9463773") +AnnotationAssertion( "Wikipedia:Oxygen") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "dioxygen") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "Disauerstoff") +AnnotationAssertion(Annotation( "ChEBI") "E 948") +AnnotationAssertion(Annotation( "ChEBI") "E-948") +AnnotationAssertion(Annotation( "ChEBI") "E948") +AnnotationAssertion(Annotation( "IUPAC") "O2") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "O2") +AnnotationAssertion(Annotation( "UniProt") "O2") +AnnotationAssertion(Annotation( "PDBeChem") "OXYGEN MOLECULE") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Oxygen") +AnnotationAssertion(Annotation( "MolBase") "[OO]") +AnnotationAssertion(Annotation( "ChEBI") "dioxygene") +AnnotationAssertion(Annotation( "ChEBI") "molecular oxygen") +AnnotationAssertion( "CHEBI:15379") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "dioxygen") +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (ATP) + +AnnotationAssertion( "An adenosine 5'-phosphate in which the 5'-phosphate is a triphosphate group. It is involved in the transportation of chemical energy during metabolic pathways.") +AnnotationAssertion( "0") +AnnotationAssertion( "C10H16N5O13P3") +AnnotationAssertion( "InChI=1S/C10H16N5O13P3/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20)/t4-,6-,7-,10-/m1/s1") +AnnotationAssertion( "ZKHQWZAMYRWXGA-KQYNXXCUSA-N") +AnnotationAssertion( "507.18100") +AnnotationAssertion( "506.99575") +AnnotationAssertion( "Nc1ncnc2n(cnc12)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O") +AnnotationAssertion( "CHEBI:10789") +AnnotationAssertion( "CHEBI:10841") +AnnotationAssertion( "CHEBI:13236") +AnnotationAssertion( "CHEBI:22249") +AnnotationAssertion( "CHEBI:2359") +AnnotationAssertion( "CHEBI:40938") +AnnotationAssertion(Annotation( "Beilstein") "Beilstein:73010") +AnnotationAssertion(Annotation( "ChemIDplus") "CAS:56-65-5") +AnnotationAssertion(Annotation( "KEGG COMPOUND") "CAS:56-65-5") +AnnotationAssertion( "DrugBank:DB00171") +AnnotationAssertion(Annotation( "DrugCentral") "Drug_Central:91") +AnnotationAssertion(Annotation( "Gmelin") "Gmelin:34857") +AnnotationAssertion( "HMDB:HMDB0000538") +AnnotationAssertion( "KEGG:C00002") +AnnotationAssertion( "KEGG:D08646") +AnnotationAssertion( "KNApSAcK:C00001491") +AnnotationAssertion( "PDBeChem:ATP") +AnnotationAssertion( "Patent:US3079379") +AnnotationAssertion(Annotation( "Reaxys") "Reaxys:73010") +AnnotationAssertion( "Wikipedia:Adenosine_triphosphate") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "ATP") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "adenosine 5'-(tetrahydrogen triphosphate)") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "PDBeChem") "ADENOSINE-5'-TRIPHOSPHATE") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Adenosine 5'-triphosphate") +AnnotationAssertion(Annotation( "ChemIDplus") "Adenosine triphosphate") +AnnotationAssertion(Annotation( "IUPAC") "H4atp") +AnnotationAssertion( "CHEBI:15422") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "ATP") +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (squalene) AnnotationAssertion( "A triterpene consisting of 2,6,10,15,19,23-hexamethyltetracosane having six double bonds at the 2-, 6-, 10-, 14-, 18- and 22-positions with (all-E)-configuration.") @@ -9461,6 +17564,118 @@ SubClassOf( ObjectSomeValuesFrom( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (aldose) + +AnnotationAssertion( "Aldehydic parent sugars (polyhydroxy aldehydes H[CH(OH)]nC(=O)H, n >= 2) and their intramolecular hemiacetals.") +AnnotationAssertion( "0") +AnnotationAssertion( "C2H4O2(CH2O)n") +AnnotationAssertion( "CHEBI:13755") +AnnotationAssertion( "CHEBI:22305") +AnnotationAssertion( "CHEBI:2561") +AnnotationAssertion( "KEGG:C01370") +AnnotationAssertion( "Wikipedia:Aldose") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Aldose") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "aldoses") +AnnotationAssertion(Annotation( "UniProt") "an aldose") +AnnotationAssertion( "CHEBI:15693") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "aldose") +SubClassOf( ) + +# Class: (L-alpha-amino acid) + +AnnotationAssertion( "Any alpha-amino acid having L-configuration at the alpha-carbon.") +AnnotationAssertion( "0") +AnnotationAssertion( "C2H4NO2R") +AnnotationAssertion( "74.05870") +AnnotationAssertion( "74.02420") +AnnotationAssertion( "N[C@@H]([*])C(O)=O") +AnnotationAssertion( "CHEBI:13072") +AnnotationAssertion( "CHEBI:13243") +AnnotationAssertion( "CHEBI:13797") +AnnotationAssertion( "CHEBI:21224") +AnnotationAssertion( "CHEBI:6175") +AnnotationAssertion( "KEGG:C00151") +AnnotationAssertion(Annotation( "IUPAC") "L-alpha-amino acid") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "L-alpha-amino acids") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "L-2-Amino acid") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "L-Amino acid") +AnnotationAssertion(Annotation( "ChEBI") "L-alpha-amino acids") +AnnotationAssertion( "CHEBI:15705") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "L-alpha-amino acid") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (primary alcohol) + +AnnotationAssertion( "A primary alcohol is a compound in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it.") +AnnotationAssertion( "0") +AnnotationAssertion( "CH3OR") +AnnotationAssertion( "31.034") +AnnotationAssertion( "31.01839") +AnnotationAssertion( "*C(O)([H])[H]") +AnnotationAssertion( "CHEBI:13676") +AnnotationAssertion( "CHEBI:14887") +AnnotationAssertion( "CHEBI:26262") +AnnotationAssertion( "CHEBI:57489") +AnnotationAssertion( "CHEBI:8406") +AnnotationAssertion( "KEGG:C00226") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Primary alcohol") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "1-Alcohol") +AnnotationAssertion(Annotation( "UniProt") "a primary alcohol") +AnnotationAssertion(Annotation( "ChEBI") "primary alcohols") +AnnotationAssertion( "CHEBI:15734") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "primary alcohol") +SubClassOf( ) + +# Class: (formate) + +AnnotationAssertion( "A monocarboxylic acid anion that is the conjugate base of formic acid. Induces severe metabolic acidosis and ocular injury in human subjects.") +AnnotationAssertion( "-1") +AnnotationAssertion( "CHO2") +AnnotationAssertion( "InChI=1S/CH2O2/c2-1-3/h1H,(H,2,3)/p-1") +AnnotationAssertion( "BDAGIHXWWSANSR-UHFFFAOYSA-M") +AnnotationAssertion( "45.01744") +AnnotationAssertion( "44.99820") +AnnotationAssertion( "[H]C([O-])=O") +AnnotationAssertion( "CHEBI:14276") +AnnotationAssertion( "CHEBI:24081") +AnnotationAssertion(Annotation( "Beilstein") "Beilstein:1901205") +AnnotationAssertion(Annotation( "ChemIDplus") "CAS:71-47-6") +AnnotationAssertion(Annotation( "NIST Chemistry WebBook") "CAS:71-47-6") +AnnotationAssertion(Annotation( "Gmelin") "Gmelin:1006") +AnnotationAssertion( "HMDB:HMDB0000142") +AnnotationAssertion( "KEGG:C00058") +AnnotationAssertion( "MetaCyc:FORMATE") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:17190852") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:3946945") +AnnotationAssertion(Annotation( "Reaxys") "Reaxys:1901205") +AnnotationAssertion(Annotation( "UM-BBD") "UM-BBD_compID:c0106") +AnnotationAssertion( "Wikipedia:Formate") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "formate") +AnnotationAssertion(Annotation( "UniProt") "formate") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "NIST_Chemistry_WebBook") "HCO2 anion") +AnnotationAssertion(Annotation( "ChEBI") "aminate") +AnnotationAssertion(Annotation( "ChEBI") "formiate") +AnnotationAssertion(Annotation( "ChemIDplus") "formic acid, ion(1-)") +AnnotationAssertion(Annotation( "ChEBI") "formylate") +AnnotationAssertion(Annotation( "ChEBI") "hydrogen carboxylate") +AnnotationAssertion(Annotation( "ChEBI") "methanoate") +AnnotationAssertion( "CHEBI:15740") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "formate") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (polypeptide) AnnotationAssertion( "A peptide containing ten or more amino acid residues.") @@ -9479,6 +17694,139 @@ AnnotationAssertion(rdfs:label "pol SubClassOf( ) SubClassOf( ) +# Class: (D-glutamic acid) + +AnnotationAssertion( "An optically active form of glutamic acid having D-configuration.") +AnnotationAssertion( "0") +AnnotationAssertion( "C5H9NO4") +AnnotationAssertion( "InChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m1/s1") +AnnotationAssertion( "WHUUTDBJXJRKMK-GSVOUGTGSA-N") +AnnotationAssertion( "147.12930") +AnnotationAssertion( "147.05316") +AnnotationAssertion( "N[C@H](CCC(O)=O)C(O)=O") +AnnotationAssertion( "CHEBI:21023") +AnnotationAssertion( "CHEBI:4183") +AnnotationAssertion(Annotation( "Beilstein") "Beilstein:1723800") +AnnotationAssertion(Annotation( "ChemIDplus") "CAS:6893-26-1") +AnnotationAssertion(Annotation( "KEGG COMPOUND") "CAS:6893-26-1") +AnnotationAssertion(Annotation( "NIST Chemistry WebBook") "CAS:6893-26-1") +AnnotationAssertion( "DrugBank:DB02517") +AnnotationAssertion(Annotation( "Gmelin") "Gmelin:201189") +AnnotationAssertion( "HMDB:HMDB0003339") +AnnotationAssertion( "KEGG:C00217") +AnnotationAssertion( "KNApSAcK:C00019577") +AnnotationAssertion( "MetaCyc:D-GLT") +AnnotationAssertion( "PDBeChem:DGL") +AnnotationAssertion(Annotation( "Reaxys") "Reaxys:1723800") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "(2R)-2-aminopentanedioic acid") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "D-Glutamic acid") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "D-glutamic acid") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "(R)-2-aminopentanedioic acid") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "D-2-Aminoglutaric acid") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "D-Glutaminic acid") +AnnotationAssertion(Annotation( "ChEBI") "D-Glutaminsaeure") +AnnotationAssertion(Annotation( "PDBeChem") "DGL") +AnnotationAssertion(Annotation( "ChemIDplus") "glutamic acid D-form") +AnnotationAssertion( "CHEBI:15966") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "D-glutamic acid") +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (polynucleotide) + +AnnotationAssertion( "A nucleobase-containing molecular entity with a polymeric structure comprised of a linear sequence of 13 or more nucleotide residues.") +AnnotationAssertion( "0") +AnnotationAssertion( "(C5H8O6PR)n.C10H17O10PR2") +AnnotationAssertion( "CHEBI:13672") +AnnotationAssertion( "CHEBI:14859") +AnnotationAssertion( "CHEBI:8312") +AnnotationAssertion( "KEGG:C00419") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Polynucleotide") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "polynucleotides") +AnnotationAssertion( "CHEBI:15986") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "polynucleotide") +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (L-glutamic acid) + +AnnotationAssertion( "An optically active form of glutamic acid having L-configuration.") +AnnotationAssertion( "0") +AnnotationAssertion( "C5H9NO4") +AnnotationAssertion( "InChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m0/s1") +AnnotationAssertion( "WHUUTDBJXJRKMK-VKHMYHEASA-N") +AnnotationAssertion( "147.12930") +AnnotationAssertion( "147.05316") +AnnotationAssertion( "N[C@@H](CCC(O)=O)C(O)=O") +AnnotationAssertion( "CHEBI:21304") +AnnotationAssertion( "CHEBI:42825") +AnnotationAssertion( "CHEBI:6224") +AnnotationAssertion( "BPDB:2297") +AnnotationAssertion(Annotation( "Beilstein") "Beilstein:1723801") +AnnotationAssertion(Annotation( "ChemIDplus") "CAS:56-86-0") +AnnotationAssertion(Annotation( "KEGG COMPOUND") "CAS:56-86-0") +AnnotationAssertion(Annotation( "NIST Chemistry WebBook") "CAS:56-86-0") +AnnotationAssertion( "DrugBank:DB00142") +AnnotationAssertion(Annotation( "DrugCentral") "Drug_Central:1310") +AnnotationAssertion(Annotation( "Gmelin") "Gmelin:3502") +AnnotationAssertion( "HMDB:HMDB0000148") +AnnotationAssertion( "KEGG:C00025") +AnnotationAssertion( "KEGG:D00007") +AnnotationAssertion( "KNApSAcK:C00001358") +AnnotationAssertion( "LINCS:LSM-36375") +AnnotationAssertion( "MetaCyc:GLT") +AnnotationAssertion( "PDBeChem:GLU_LFOH") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:15739367") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:15930465") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:16719819") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:16892196") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:19581495") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:22219301") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:22735334") +AnnotationAssertion(Annotation( "Reaxys") "Reaxys:1723801") +AnnotationAssertion( "Wikipedia:L-Glutamic_Acid") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "(2S)-2-aminopentanedioic acid") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "L-Glutamic acid") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "L-glutamic acid") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "(S)-2-aminopentanedioic acid") +AnnotationAssertion(Annotation( "NIST_Chemistry_WebBook") "(S)-glutamic acid") +AnnotationAssertion(Annotation( "ChEBI") "E") +AnnotationAssertion(Annotation( "PDBeChem") "GLUTAMIC ACID") +AnnotationAssertion(Annotation( "ChEBI") "Glu") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Glutamate") +AnnotationAssertion(Annotation( "ChEBI") "L-Glu") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "L-Glutaminic acid") +AnnotationAssertion(Annotation( "ChEBI") "L-Glutaminsaeure") +AnnotationAssertion(Annotation( "ChEBI") Annotation( ) "acide glutamique") +AnnotationAssertion(Annotation( "ChEBI") Annotation( ) "acido glutamico") +AnnotationAssertion(Annotation( "ChEBI") Annotation( ) "acidum glutamicum") +AnnotationAssertion(Annotation( "ChEBI") Annotation( ) "glutamic acid") +AnnotationAssertion( "CHEBI:16015") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "L-glutamic acid") +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (ammonia) AnnotationAssertion( "An azane that consists of a single nitrogen atom covelently bonded to three hydrogen atoms.") @@ -9680,6 +18028,40 @@ SubClassOf( ObjectSomeValuesFrom( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (hydroxide) + +AnnotationAssertion( "-1") +AnnotationAssertion( "HO") +AnnotationAssertion( "InChI=1S/H2O/h1H2/p-1") +AnnotationAssertion( "XLYOFNOQVPJJNP-UHFFFAOYSA-M") +AnnotationAssertion( "17.00734") +AnnotationAssertion( "17.00329") +AnnotationAssertion( "[O-][H]") +AnnotationAssertion( "CHEBI:13365") +AnnotationAssertion( "CHEBI:13419") +AnnotationAssertion( "CHEBI:44641") +AnnotationAssertion( "CHEBI:5594") +AnnotationAssertion(Annotation( "ChemIDplus") "CAS:14280-30-9") +AnnotationAssertion(Annotation( "NIST Chemistry WebBook") "CAS:14280-30-9") +AnnotationAssertion(Annotation( "Gmelin") "Gmelin:24714") +AnnotationAssertion( "KEGG:C01328") +AnnotationAssertion( "PDBeChem:OH") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "hydridooxygenate(1-)") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "hydroxide") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "oxidanide") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "HO-") +AnnotationAssertion(Annotation( "PDBeChem") "HYDROXIDE ION") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Hydroxide ion") +AnnotationAssertion(Annotation( "IUPAC") "OH(-)") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "OH-") +AnnotationAssertion( "CHEBI:16234") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "hydroxide") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (phospholipid) AnnotationAssertion( "A lipid containing phosphoric acid as a mono- or di-ester. The term encompasses phosphatidic acids and phosphoglycerides.") @@ -9699,6 +18081,81 @@ SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (adenosine) + +AnnotationAssertion( "A ribonucleoside composed of a molecule of adenine attached to a ribofuranose moiety via a beta-N(9)-glycosidic bond.") +AnnotationAssertion( "0") +AnnotationAssertion( "C10H13N5O4") +AnnotationAssertion( "InChI=1S/C10H13N5O4/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(18)6(17)4(1-16)19-10/h2-4,6-7,10,16-18H,1H2,(H2,11,12,13)/t4-,6-,7-,10-/m1/s1") +AnnotationAssertion( "OIRDTQYFTABQOQ-KQYNXXCUSA-N") +AnnotationAssertion( "267.24152") +AnnotationAssertion( "267.09675") +AnnotationAssertion( "Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O") +AnnotationAssertion( "CHEBI:13734") +AnnotationAssertion( "CHEBI:22237") +AnnotationAssertion( "CHEBI:2472") +AnnotationAssertion( "CHEBI:40558") +AnnotationAssertion( "CHEBI:40825") +AnnotationAssertion( "CHEBI:40906") +AnnotationAssertion(Annotation( "Beilstein") "Beilstein:93029") +AnnotationAssertion(Annotation( "ChemIDplus") "CAS:58-61-7") +AnnotationAssertion(Annotation( "KEGG COMPOUND") "CAS:58-61-7") +AnnotationAssertion(Annotation( "NIST Chemistry WebBook") "CAS:58-61-7") +AnnotationAssertion( "DrugBank:DB00640") +AnnotationAssertion(Annotation( "DrugCentral") "Drug_Central:90") +AnnotationAssertion( "ECMDB:ECMDB00050") +AnnotationAssertion(Annotation( "Gmelin") "Gmelin:53385") +AnnotationAssertion( "HMDB:HMDB0000050") +AnnotationAssertion( "KEGG:C00212") +AnnotationAssertion( "KEGG:D00045") +AnnotationAssertion( "KNApSAcK:C00007444") +AnnotationAssertion( "LINCS:LSM-28568") +AnnotationAssertion( "MetaCyc:ADENOSINE") +AnnotationAssertion( "PDBeChem:ADN") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:11213237") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:11820865") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:11978011") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:16183671") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:16917093") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:17190852") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:18000974") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:323854") +AnnotationAssertion(Annotation( "Reaxys") "Reaxys:93029") +AnnotationAssertion( "Wikipedia:Adenosine") +AnnotationAssertion( "YMDB:YMDB00058") +AnnotationAssertion(Annotation( "PDBeChem") "ADENOSINE") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Adenosine") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "adenosine") +AnnotationAssertion(Annotation( "UniProt") "adenosine") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "DrugBank") "(2R,3R,4S,5R)-2-(6-aminopurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol") +AnnotationAssertion(Annotation( "ChemIDplus") "6-Amino-9-beta-D-ribofuranosyl-9H-purine") +AnnotationAssertion(Annotation( "ChemIDplus") "9-beta-D-Ribofuranosidoadenine") +AnnotationAssertion(Annotation( "ChemIDplus") "9-beta-D-Ribofuranosyl-9H-purin-6-amine") +AnnotationAssertion(Annotation( "ChEBI") "9-beta-D-ribofuranosyl-9H-purin-6-amine") +AnnotationAssertion(Annotation( "CBN") "Ade-Rib") +AnnotationAssertion(Annotation( "DrugBank") "Adenine Deoxyribonucleoside") +AnnotationAssertion(Annotation( "DrugBank") Annotation( ) "Adenocard") +AnnotationAssertion(Annotation( "DrugBank") Annotation( ) "Adenocor") +AnnotationAssertion(Annotation( "DrugBank") Annotation( ) "Adenoscan") +AnnotationAssertion(Annotation( "ChEBI") "Adenosin") +AnnotationAssertion(Annotation( "DrugBank") "Adenyldeoxyriboside") +AnnotationAssertion(Annotation( "CBN") "Ado") +AnnotationAssertion(Annotation( "DrugBank") "Deoxyadenosine") +AnnotationAssertion(Annotation( "DrugBank") "Desoxyadenosine") +AnnotationAssertion(Annotation( "ChemIDplus") "beta-D-Adenosine") +AnnotationAssertion( "CHEBI:16335") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "adenosine") +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (hyaluronic acid) AnnotationAssertion( "A mucopolysaccharide composed of N-acetylglucosamine and glucuronic acid subunits. It is found in the connective tissues of vertebrates. A principal constituent of the extracellular matrix (ECM), it mediates the growth and metastasis of tumour cells.") @@ -9893,6 +18350,102 @@ SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (noradrenaline(1+)) + +AnnotationAssertion( "+1") +AnnotationAssertion( "C8H12NO3") +AnnotationAssertion( "InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2/p+1") +AnnotationAssertion( "SFLSHLFXELFNJZ-UHFFFAOYSA-O") +AnnotationAssertion( "170.187") +AnnotationAssertion( "170.08117") +AnnotationAssertion( "C1=CC(=CC(=C1O)O)C(C[NH3+])O") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "UniProt") "noradrenaline") +AnnotationAssertion( "CHEBI:166902") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "noradrenaline(1+)") +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (nucleoside 5'-phosphate) + +AnnotationAssertion( "A ribosyl or deoxyribosyl derivative of a pyrimidine or purine base in which C-5 of the ribose ring is mono-, di-, tri- or tetra-phosphorylated.") +AnnotationAssertion( "0") +AnnotationAssertion( "C5H9O6PR2") +AnnotationAssertion( "196.09510") +AnnotationAssertion( "196.01367") +AnnotationAssertion( "O[C@H]1[C@@H]([*])[C@H]([*])O[C@@H]1COP(O)(O)=O") +AnnotationAssertion( "CHEBI:14674") +AnnotationAssertion( "CHEBI:25603") +AnnotationAssertion( "CHEBI:7650") +AnnotationAssertion( "KEGG:C01117") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Nucleoside 5'-phosphate") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "nucleoside 5'-phosphates") +AnnotationAssertion( "CHEBI:16701") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "nucleoside 5'-phosphate") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (adenine) + +AnnotationAssertion( "The parent compound of the 6-aminopurines, composed of a purine having an amino group at C-6.") +AnnotationAssertion( "0") +AnnotationAssertion( "C5H5N5") +AnnotationAssertion( "InChI=1S/C5H5N5/c6-4-3-5(9-1-7-3)10-2-8-4/h1-2H,(H3,6,7,8,9,10)") +AnnotationAssertion( "GFFGJBXGBJISGV-UHFFFAOYSA-N") +AnnotationAssertion( "135.12690") +AnnotationAssertion( "135.05450") +AnnotationAssertion( "Nc1ncnc2[nH]cnc12") +AnnotationAssertion( "CHEBI:13733") +AnnotationAssertion( "CHEBI:22236") +AnnotationAssertion( "CHEBI:2470") +AnnotationAssertion( "CHEBI:40579") +AnnotationAssertion(Annotation( "Beilstein") "Beilstein:608603") +AnnotationAssertion(Annotation( "ChemIDplus") "CAS:73-24-5") +AnnotationAssertion(Annotation( "KEGG COMPOUND") "CAS:73-24-5") +AnnotationAssertion(Annotation( "NIST Chemistry WebBook") "CAS:73-24-5") +AnnotationAssertion( "DrugBank:DB00173") +AnnotationAssertion(Annotation( "DrugCentral") "Drug_Central:89") +AnnotationAssertion(Annotation( "Gmelin") "Gmelin:3903") +AnnotationAssertion( "HMDB:HMDB0000034") +AnnotationAssertion( "KEGG:C00147") +AnnotationAssertion( "KEGG:D00034") +AnnotationAssertion( "KNApSAcK:C00001490") +AnnotationAssertion( "MetaCyc:ADENINE") +AnnotationAssertion( "PDBeChem:ADE") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:11985597") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:12829005") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:12951489") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:15063338") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:15715490") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:17439666") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:8070089") +AnnotationAssertion(Annotation( "Reaxys") "Reaxys:608603") +AnnotationAssertion( "Wikipedia:Adenine") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "9H-purin-6-amine") +AnnotationAssertion(Annotation( "PDBeChem") "ADENINE") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Adenine") +AnnotationAssertion(Annotation( "UniProt") "adenine") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "6-Aminopurine") +AnnotationAssertion(Annotation( "ChEBI") "A") +AnnotationAssertion(Annotation( "CBN") "Ade") +AnnotationAssertion(Annotation( "NIST_Chemistry_WebBook") "Adenin") +AnnotationAssertion( "CHEBI:16708") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "adenine") +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (mineral nutrient) AnnotationAssertion( "A mineral that is an inorganic nutrient which must be ingested and absorbed in adequate amounts to satisfy a wide range of essential metabolic and/or structural functions in the human body.") @@ -9908,6 +18461,30 @@ AnnotationAssertion(rdfs:label "mi SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (D-alpha-amino acid) + +AnnotationAssertion( "0") +AnnotationAssertion( "C2H4NO2R") +AnnotationAssertion( "74.05870") +AnnotationAssertion( "74.02420") +AnnotationAssertion( "N[C@H]([*])C(O)=O") +AnnotationAssertion( "CHEBI:12909") +AnnotationAssertion( "CHEBI:13625") +AnnotationAssertion( "CHEBI:20906") +AnnotationAssertion( "CHEBI:4097") +AnnotationAssertion( "KEGG:C00405") +AnnotationAssertion(Annotation( "ChEBI") "D-alpha-amino acid") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "D-alpha-amino acids") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "D-Amino acid") +AnnotationAssertion(Annotation( "ChEBI") "D-alpha-amino acids") +AnnotationAssertion( "CHEBI:16733") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "D-alpha-amino acid") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (glycan) AnnotationAssertion( "Any oligosaccharide, polysaccharide or their derivatives consisting of monosaccharides or monosaccharide derivatives linked by glycosidic bonds. See also http://www.ontobee.org/ontology/GNO?iri=http://purl.obolibrary.org/obo/GNO_00000001.") @@ -9918,6 +18495,270 @@ AnnotationAssertion( "glycan") SubClassOf( ) +# Class: (ADP) + +AnnotationAssertion( "A purine ribonucleoside 5'-diphosphate having adenine as the nucleobase.") +AnnotationAssertion( "0") +AnnotationAssertion( "C10H15N5O10P2") +AnnotationAssertion( "InChI=1S/C10H15N5O10P2/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(24-10)1-23-27(21,22)25-26(18,19)20/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H2,11,12,13)(H2,18,19,20)/t4-,6-,7-,10-/m1/s1") +AnnotationAssertion( "XTWYTFMLZFPYCI-KQYNXXCUSA-N") +AnnotationAssertion( "427.20110") +AnnotationAssertion( "427.02942") +AnnotationAssertion( "Nc1ncnc2n(cnc12)[C@@H]1O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O") +AnnotationAssertion( "CHEBI:13222") +AnnotationAssertion( "CHEBI:22244") +AnnotationAssertion( "CHEBI:2342") +AnnotationAssertion( "CHEBI:40553") +AnnotationAssertion(Annotation( "Beilstein") "Beilstein:67722") +AnnotationAssertion(Annotation( "KEGG COMPOUND") "CAS:20398-34-9") +AnnotationAssertion(Annotation( "ChemIDplus") "CAS:58-64-0") +AnnotationAssertion(Annotation( "KEGG COMPOUND") "CAS:58-64-0") +AnnotationAssertion( "COMe:MOL000173") +AnnotationAssertion( "DrugBank:DB03431") +AnnotationAssertion(Annotation( "Gmelin") "Gmelin:88452") +AnnotationAssertion( "KEGG:C00008") +AnnotationAssertion( "KEGG:G11113") +AnnotationAssertion( "KNApSAcK:C00019353") +AnnotationAssertion( "PDBeChem:ADP") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:16295522") +AnnotationAssertion(Annotation( "Reaxys") "Reaxys:67722") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "ADP") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "adenosine 5'-(trihydrogen diphosphate)") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChemIDplus") "5'-adenylphosphoric acid") +AnnotationAssertion(Annotation( "PDBeChem") "ADENOSINE-5'-DIPHOSPHATE") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Adenosine 5'-diphosphate") +AnnotationAssertion(Annotation( "IUPAC") "H3adp") +AnnotationAssertion( "CHEBI:16761") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "ADP") +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (tryptamine) + +AnnotationAssertion( "An aminoalkylindole consisting of indole having a 2-aminoethyl group at the 3-position.") +AnnotationAssertion( "0") +AnnotationAssertion( "C10H12N2") +AnnotationAssertion( "InChI=1S/C10H12N2/c11-6-5-8-7-12-10-4-2-1-3-9(8)10/h1-4,7,12H,5-6,11H2") +AnnotationAssertion( "APJYDQYYACXCRM-UHFFFAOYSA-N") +AnnotationAssertion( "160.21570") +AnnotationAssertion( "160.10005") +AnnotationAssertion( "NCCc1c[nH]c2ccccc12") +AnnotationAssertion( "CHEBI:15274") +AnnotationAssertion( "CHEBI:27161") +AnnotationAssertion( "CHEBI:46157") +AnnotationAssertion( "CHEBI:9767") +AnnotationAssertion(Annotation( "Beilstein") "Beilstein:125513") +AnnotationAssertion(Annotation( "ChemIDplus") "CAS:61-54-1") +AnnotationAssertion(Annotation( "KEGG COMPOUND") "CAS:61-54-1") +AnnotationAssertion(Annotation( "NIST Chemistry WebBook") "CAS:61-54-1") +AnnotationAssertion( "DrugBank:DB08653") +AnnotationAssertion(Annotation( "Gmelin") "Gmelin:603448") +AnnotationAssertion( "HMDB:HMDB0000303") +AnnotationAssertion( "KEGG:C00398") +AnnotationAssertion( "KNApSAcK:C00001434") +AnnotationAssertion( "MetaCyc:TRYPTAMINE") +AnnotationAssertion( "PDBeChem:TSS") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:16126914") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:22770225") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:24345948") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:24558969") +AnnotationAssertion(Annotation( "Reaxys") "Reaxys:125513") +AnnotationAssertion( "Wikipedia:Tryptamine") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "2-(1H-indol-3-yl)ethanamine") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Tryptamine") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "NIST_Chemistry_WebBook") "1H-indole-3-ethanamine") +AnnotationAssertion(Annotation( "PDBeChem") "2-(1H-INDOL-3-YL)ETHANAMINE") +AnnotationAssertion(Annotation( "ChemIDplus") "2-(3-indolyl)ethylamine") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "3-(2-Aminoethyl)indole") +AnnotationAssertion( "CHEBI:16765") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "tryptamine") +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (melatonin) + +AnnotationAssertion( "A member of the class of acetamides that is acetamide in which one of the hydrogens attached to the nitrogen atom is replaced by a 2-(5-methoxy-1H-indol-3-yl)ethyl group. It is a hormone secreted by the pineal gland in humans.") +AnnotationAssertion( "0") +AnnotationAssertion( "C13H16N2O2") +AnnotationAssertion( "InChI=1S/C13H16N2O2/c1-9(16)14-6-5-10-8-15-13-4-3-11(17-2)7-12(10)13/h3-4,7-8,15H,5-6H2,1-2H3,(H,14,16)") +AnnotationAssertion( "DRLFMBDRBRZALE-UHFFFAOYSA-N") +AnnotationAssertion( "232.283") +AnnotationAssertion( "232.12118") +AnnotationAssertion( "C=1C=C(C=C2C(=CNC12)CCNC(=O)C)OC") +AnnotationAssertion( "CHEBI:14577") +AnnotationAssertion( "CHEBI:25180") +AnnotationAssertion( "CHEBI:6730") +AnnotationAssertion(Annotation( "Beilstein") "Beilstein:205542") +AnnotationAssertion(Annotation( "ChemIDplus") "CAS:73-31-4") +AnnotationAssertion(Annotation( "KEGG COMPOUND") "CAS:73-31-4") +AnnotationAssertion(Annotation( "NIST Chemistry WebBook") "CAS:73-31-4") +AnnotationAssertion( "DrugBank:DB01065") +AnnotationAssertion(Annotation( "DrugCentral") "Drug_Central:1672") +AnnotationAssertion( "HMDB:HMDB0001389") +AnnotationAssertion( "KEGG:C01598") +AnnotationAssertion( "KEGG:D08170") +AnnotationAssertion( "LINCS:LSM-4779") +AnnotationAssertion( "MetaCyc:N-ACETYL-5-METHOXY-TRYPTAMINE") +AnnotationAssertion( "PDBeChem:ML1") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:16678784") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:18212404") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:18485664") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:8290600") +AnnotationAssertion(Annotation( "Reaxys") "Reaxys:205542") +AnnotationAssertion( "Wikipedia:Melatonin") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Melatonin") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "N-[2-(5-methoxy-1H-indol-3-yl)ethyl]acetamide") +AnnotationAssertion(Annotation( "UniProt") "melatonin") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChemIDplus") "5-methoxy-N-acetyltryptamine") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "N-Acetyl-5-methoxytryptamine") +AnnotationAssertion(Annotation( "NIST_Chemistry_WebBook") "N-[2-(5-methoxyindol-3-yl)ethyl]acetamide") +AnnotationAssertion(Annotation( "ChEBI") "melatonine") +AnnotationAssertion( "CHEBI:16796") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "melatonin") +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (nucleoside 5'-diphosphate) + +AnnotationAssertion( "0") +AnnotationAssertion( "C5H11O10P2R") +AnnotationAssertion( "293.08240") +AnnotationAssertion( "292.98274") +AnnotationAssertion( "O[C@H]1[C@H]([*])O[C@H](COP(O)(=O)OP(O)(O)=O)[C@H]1O") +AnnotationAssertion( "CHEBI:13401") +AnnotationAssertion( "CHEBI:13662") +AnnotationAssertion( "CHEBI:14675") +AnnotationAssertion( "CHEBI:25606") +AnnotationAssertion( "CHEBI:7428") +AnnotationAssertion( "CHEBI:7652") +AnnotationAssertion( "KEGG:C00454") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "NDP") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Nucleoside diphosphate") +AnnotationAssertion(Annotation( "ChEBI") "nucleoside diphosphates") +AnnotationAssertion( "CHEBI:16862") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "nucleoside 5'-diphosphate") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (gamma-aminobutyric acid) + +AnnotationAssertion( "A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.") +AnnotationAssertion( "0") +AnnotationAssertion( "C4H9NO2") +AnnotationAssertion( "InChI=1S/C4H9NO2/c5-3-1-2-4(6)7/h1-3,5H2,(H,6,7)") +AnnotationAssertion( "BTCSSZJGUNDROE-UHFFFAOYSA-N") +AnnotationAssertion( "103.11980") +AnnotationAssertion( "103.06333") +AnnotationAssertion( "NCCCC(O)=O") +AnnotationAssertion( "CHEBI:1786") +AnnotationAssertion( "CHEBI:193777") +AnnotationAssertion( "CHEBI:20318") +AnnotationAssertion( "CHEBI:40483") +AnnotationAssertion( "BPDB:2298") +AnnotationAssertion(Annotation( "Beilstein") "Beilstein:906818") +AnnotationAssertion(Annotation( "ChemIDplus") "CAS:56-12-2") +AnnotationAssertion(Annotation( "KEGG COMPOUND") "CAS:56-12-2") +AnnotationAssertion(Annotation( "NIST Chemistry WebBook") "CAS:56-12-2") +AnnotationAssertion( "DrugBank:DB02530") +AnnotationAssertion(Annotation( "DrugCentral") "Drug_Central:1262") +AnnotationAssertion(Annotation( "Gmelin") "Gmelin:49775") +AnnotationAssertion( "HMDB:HMDB0000112") +AnnotationAssertion( "KEGG:C00334") +AnnotationAssertion( "KEGG:D00058") +AnnotationAssertion( "KNApSAcK:C00001337") +AnnotationAssertion(Annotation( "LIPID MAPS") "LIPID_MAPS_instance:LMFA01100039") +AnnotationAssertion( "MetaCyc:4-AMINO-BUTYRATE") +AnnotationAssertion( "PDBeChem:ABU") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:10630630") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:10930630") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:16276116") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:21614609") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:22770225") +AnnotationAssertion(Annotation( "Reaxys") "Reaxys:906818") +AnnotationAssertion( "Wikipedia:Gamma-Aminobutyric_acid") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "4-aminobutanoic acid") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "gamma-Aminobutyric acid") +AnnotationAssertion(Annotation( "NIST_Chemistry_WebBook") "gamma-aminobutyric acid") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "4-Aminobutanoic acid") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "4-Aminobutyric acid") +AnnotationAssertion(Annotation( "ChEBI") "4-aminobutanoic acid") +AnnotationAssertion(Annotation( "ChEBI") "4-aminobutyric acid") +AnnotationAssertion(Annotation( "ChEBI") "4Abu") +AnnotationAssertion(Annotation( "IUPHAR") "GABA") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "GABA") +AnnotationAssertion(Annotation( "PDBeChem") "GAMMA-AMINO-BUTANOIC ACID") +AnnotationAssertion(Annotation( "NIST_Chemistry_WebBook") "gamma-Aminobuttersaeure") +AnnotationAssertion(Annotation( "NIST_Chemistry_WebBook") "gamma-amino-n-butyric acid") +AnnotationAssertion(Annotation( "NIST_Chemistry_WebBook") "gamma-aminobutanoic acid") +AnnotationAssertion(Annotation( "NIST_Chemistry_WebBook") "omega-aminobutyric acid") +AnnotationAssertion(Annotation( "ChemIDplus") "piperidic acid") +AnnotationAssertion(Annotation( "ChemIDplus") "piperidinic acid") +AnnotationAssertion( "CHEBI:16865") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "gamma-aminobutyric acid") +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (D-ribose) + +AnnotationAssertion( "A ribose in which the chiral carbon atom furthest away from the aldehyde group (C4') has the same configuration as in D-glyceraldehyde.") +AnnotationAssertion( "0") +AnnotationAssertion( "C5H10O5") +AnnotationAssertion( "150.12990") +AnnotationAssertion( "150.05282") +AnnotationAssertion( "CHEBI:13011") +AnnotationAssertion( "CHEBI:21078") +AnnotationAssertion( "DrugBank:DB01936") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:24404872") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:24752650") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "D-ribo-pentose") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "D-ribose") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "JCBN") "D-Rib") +AnnotationAssertion( "CHEBI:16988") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "D-ribose") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (bilirubin IXalpha) AnnotationAssertion( "A member of the class of biladienes that is a linear tetrapyrrole with the dipyrrole units being of both exovinyl and endovinyl type. A product of heme degradation, it is produced in the reticuloendothelial system by the reduction of biliverdin and transported to the liver as a complex with serum albumin.") @@ -9970,6 +18811,104 @@ SubClassOf( ObjectSomeValuesFrom( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (deoxyribonucleic acid) + +AnnotationAssertion( "High molecular weight, linear polymers, composed of nucleotides containing deoxyribose and linked by phosphodiester bonds; DNA contain the genetic information of organisms.") +AnnotationAssertion( "CHEBI:13302") +AnnotationAssertion( "CHEBI:21123") +AnnotationAssertion( "CHEBI:33698") +AnnotationAssertion( "CHEBI:4291") +AnnotationAssertion(Annotation( "ChemIDplus") "CAS:9007-49-2") +AnnotationAssertion(Annotation( "KEGG COMPOUND") "CAS:9007-49-2") +AnnotationAssertion( "KEGG:C00039") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Deoxyribonucleic acid") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "deoxyribonucleic acids") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "(Deoxyribonucleotide)m") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "(Deoxyribonucleotide)n") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "(Deoxyribonucleotide)n+m") +AnnotationAssertion(Annotation( "IUPAC") "DNA") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "DNA") +AnnotationAssertion(Annotation( "UniProt") "DNA") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "DNAn") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "DNAn+1") +AnnotationAssertion(Annotation( "ChEBI") "DNS") +AnnotationAssertion(Annotation( "ChEBI") "Desoxyribonukleinsaeure") +AnnotationAssertion(Annotation( "ChEBI") "deoxyribonucleic acids") +AnnotationAssertion(Annotation( "ChemIDplus") "desoxyribose nucleic acid") +AnnotationAssertion(Annotation( "ChEBI") "thymus nucleic acid") +AnnotationAssertion( "CHEBI:16991") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "deoxyribonucleic acid") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (progesterone) + +AnnotationAssertion( "A C21-steroid hormone in which a pregnane skeleton carries oxo substituents at positions 3 and 20 and is unsaturated at C(4)-C(5). As a hormone, it is involved in the female menstrual cycle, pregnancy and embryogenesis of humans and other species.") +AnnotationAssertion( "0") +AnnotationAssertion( "C21H30O2") +AnnotationAssertion( "InChI=1S/C21H30O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h12,16-19H,4-11H2,1-3H3/t16-,17+,18-,19-,20-,21+/m0/s1") +AnnotationAssertion( "RJKFOVLPORLFTN-LEKSSAKUSA-N") +AnnotationAssertion( "314.46170") +AnnotationAssertion( "314.22458") +AnnotationAssertion( "[H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@]1(C)[C@H](CC[C@@]21[H])C(C)=O") +AnnotationAssertion( "CHEBI:14896") +AnnotationAssertion( "CHEBI:18798") +AnnotationAssertion( "CHEBI:26269") +AnnotationAssertion( "CHEBI:439") +AnnotationAssertion( "CHEBI:45786") +AnnotationAssertion( "CHEBI:8453") +AnnotationAssertion(Annotation( "Beilstein") "Beilstein:1915950") +AnnotationAssertion(Annotation( "ChemIDplus") "CAS:57-83-0") +AnnotationAssertion(Annotation( "KEGG COMPOUND") "CAS:57-83-0") +AnnotationAssertion(Annotation( "NIST Chemistry WebBook") "CAS:57-83-0") +AnnotationAssertion( "DrugBank:DB00396") +AnnotationAssertion(Annotation( "DrugCentral") "Drug_Central:2279") +AnnotationAssertion(Annotation( "Gmelin") "Gmelin:708590") +AnnotationAssertion( "HMDB:HMDB0001830") +AnnotationAssertion( "KEGG:C00410") +AnnotationAssertion( "KEGG:D00066") +AnnotationAssertion( "MetaCyc:PROGESTERONE") +AnnotationAssertion( "PDBeChem:STR") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:10438974") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:9506942") +AnnotationAssertion(Annotation( "Reaxys") "Reaxys:1915950") +AnnotationAssertion( "Wikipedia:Progesterone") +AnnotationAssertion(Annotation( "PDBeChem") "PROGESTERONE") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Progesterone") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "pregn-4-ene-3,20-dione") +AnnotationAssertion(Annotation( "UniProt") "progesterone") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "(S)-4-Pregnene-3,20-dione") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "(S)-Pregn-4-en-3,20-dione") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "(S)-Progesterone") +AnnotationAssertion(Annotation( "NIST_Chemistry_WebBook") "17alpha-progesterone") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "4-Pregnene-3,20-dione") +AnnotationAssertion(Annotation( "NIST_Chemistry_WebBook") "Agolutin") +AnnotationAssertion(Annotation( "ChEBI") "Akrolutin") +AnnotationAssertion(Annotation( "ChemIDplus") "Crinone") +AnnotationAssertion(Annotation( "ChEBI") "Delta(4)-pregnene-3,20-dione") +AnnotationAssertion(Annotation( "ChEBI") "Gelbkoerperhormon") +AnnotationAssertion(Annotation( "ChEBI") "Progesteron") +AnnotationAssertion(Annotation( "ChemIDplus") "corpus luteum hormone") +AnnotationAssertion(Annotation( "ChemIDplus") "luteohormone") +AnnotationAssertion( "CHEBI:17026") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "progesterone") +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (chitin) AnnotationAssertion( "An aminoglycan consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues.") @@ -9999,6 +18938,34 @@ SubClassOf( ObjectSomeValuesFrom( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (ketone) + +AnnotationAssertion( "A compound in which a carbonyl group is bonded to two carbon atoms: R2C=O (neither R may be H).") +AnnotationAssertion( "0") +AnnotationAssertion( "COR2") +AnnotationAssertion( "28.010") +AnnotationAssertion( "27.99491") +AnnotationAssertion( "[*]C([*])=O") +AnnotationAssertion( "CHEBI:13427") +AnnotationAssertion( "CHEBI:13646") +AnnotationAssertion( "CHEBI:24974") +AnnotationAssertion( "CHEBI:6127") +AnnotationAssertion( "CHEBI:8742") +AnnotationAssertion( "KEGG:C01450") +AnnotationAssertion( "Wikipedia:Ketone") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Ketone") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "ketones") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "Keton") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "R-CO-R'") +AnnotationAssertion(Annotation( "UniProt") "a ketone") +AnnotationAssertion(Annotation( "ChEBI") "cetone") +AnnotationAssertion(Annotation( "ChEBI") "ketones") +AnnotationAssertion( "CHEBI:17087") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "ketone") +SubClassOf( ) + # Class: (glycoprotein) AnnotationAssertion( "A compound in which a carbohydrate component is covalently bound to a protein component.") @@ -10022,6 +18989,62 @@ AnnotationAssertion(rdfs:label "gly SubClassOf( ) SubClassOf( ) +# Class: (glucose) + +AnnotationAssertion( "An aldohexose used as a source of energy and metabolic intermediate.") +AnnotationAssertion( "0") +AnnotationAssertion( "C6H12O6") +AnnotationAssertion( "180.15588") +AnnotationAssertion( "180.06339") +AnnotationAssertion( "CHEBI:14313") +AnnotationAssertion( "CHEBI:24277") +AnnotationAssertion( "CHEBI:33929") +AnnotationAssertion( "CHEBI:5418") +AnnotationAssertion(Annotation( "KEGG COMPOUND") "CAS:50-99-7") +AnnotationAssertion( "KEGG:C00293") +AnnotationAssertion( "Wikipedia:Glucose") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Glucose") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "gluco-hexose") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "glucose") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "DL-glucose") +AnnotationAssertion(Annotation( "JCBN") "Glc") +AnnotationAssertion(Annotation( "ChEBI") "Glukose") +AnnotationAssertion( "CHEBI:17234") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "glucose") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (7H-purine) + +AnnotationAssertion( "The 7H-tautomer of purine.") +AnnotationAssertion( "0") +AnnotationAssertion( "C5H4N4") +AnnotationAssertion( "InChI=1S/C5H4N4/c1-4-5(8-2-6-1)9-3-7-4/h1-3H,(H,6,7,8,9)") +AnnotationAssertion( "KDCGOANMDULRCW-UHFFFAOYSA-N") +AnnotationAssertion( "120.11222") +AnnotationAssertion( "120.04360") +AnnotationAssertion( "c1ncc2[nH]cnc2n1") +AnnotationAssertion( "CHEBI:14968") +AnnotationAssertion( "CHEBI:8639") +AnnotationAssertion(Annotation( "Beilstein") "Beilstein:3200") +AnnotationAssertion(Annotation( "Gmelin") "Gmelin:601779") +AnnotationAssertion( "HMDB:HMDB0001366") +AnnotationAssertion( "KEGG:C15587") +AnnotationAssertion(Annotation( "Reaxys") "Reaxys:3200") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "7H-purine") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Purine") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Purine base") +AnnotationAssertion( "CHEBI:17258") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "7H-purine") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (ferroptosis inhibitor) AnnotationAssertion( "Any substance that inhibits the process of ferroptosis (a type of programmed cell death dependent on iron and characterized by the accumulation of lipid peroxides) in organisms.") @@ -10038,6 +19061,139 @@ AnnotationAssertion(rdfs:label "fe SubClassOf( ) SubClassOf( ) +# Class: (ferroptosis inducer) + +AnnotationAssertion( "Any substance that induces or promotes ferroptosis (a type of programmed cell death dependent on iron and characterized by the accumulation of lipid peroxides) in organisms.") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:31899616") +AnnotationAssertion(Annotation( "SUBMITTER") "PMID:32015325") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:33167414") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:34012798") +AnnotationAssertion( "Wikipedia:Ferroptosis") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "ferroptosis inducers") +AnnotationAssertion( "CHEBI:173085") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "ferroptosis inducer") +SubClassOf( ) + +# Class: (nucleoside 5'-triphoshate) + +AnnotationAssertion( "0") +AnnotationAssertion( "C5H12O13P3R") +AnnotationAssertion( "373.063") +AnnotationAssertion( "372.94908") +AnnotationAssertion( "[C@H]1([C@H]([C@@H](O)[C@@H](O1)*)O)COP(OP(OP(=O)(O)O)(=O)O)(=O)O") +AnnotationAssertion( "CHEBI:13411") +AnnotationAssertion( "CHEBI:14677") +AnnotationAssertion( "CHEBI:25610") +AnnotationAssertion( "CHEBI:7442") +AnnotationAssertion( "CHEBI:7655") +AnnotationAssertion( "KEGG:C00201") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "NTP") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Nucleoside triphosphate") +AnnotationAssertion(Annotation( "ChEBI") "nucleoside triphosphates") +AnnotationAssertion( "CHEBI:17326") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "nucleoside 5'-triphoshate") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (testosterone) + +AnnotationAssertion( "An androstanoid having 17beta-hydroxy and 3-oxo groups, together with unsaturation at C-4-C-5..") +AnnotationAssertion( "0") +AnnotationAssertion( "C19H28O2") +AnnotationAssertion( "InChI=1S/C19H28O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h11,14-17,21H,3-10H2,1-2H3/t14-,15-,16-,17-,18-,19-/m0/s1") +AnnotationAssertion( "MUMGGOZAMZWBJJ-DYKIIFRCSA-N") +AnnotationAssertion( "288.42440") +AnnotationAssertion( "288.20893") +AnnotationAssertion( "[H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@]1(C)[C@@H](O)CC[C@@]21[H]") +AnnotationAssertion( "CHEBI:15214") +AnnotationAssertion( "CHEBI:26883") +AnnotationAssertion( "CHEBI:45798") +AnnotationAssertion( "CHEBI:9461") +AnnotationAssertion(Annotation( "Beilstein") "Beilstein:1915399") +AnnotationAssertion(Annotation( "Beilstein") "Beilstein:3653705") +AnnotationAssertion(Annotation( "ChemIDplus") "CAS:58-22-0") +AnnotationAssertion(Annotation( "KEGG COMPOUND") "CAS:58-22-0") +AnnotationAssertion(Annotation( "NIST Chemistry WebBook") "CAS:58-22-0") +AnnotationAssertion( "DrugBank:DB00624") +AnnotationAssertion(Annotation( "DrugCentral") "Drug_Central:2607") +AnnotationAssertion(Annotation( "Gmelin") "Gmelin:538843") +AnnotationAssertion( "HMDB:HMDB0000234") +AnnotationAssertion( "KEGG:C00535") +AnnotationAssertion( "KEGG:D00075") +AnnotationAssertion( "KNApSAcK:C00003675") +AnnotationAssertion(Annotation( "LIPID MAPS") "LIPID_MAPS_instance:LMST02020002") +AnnotationAssertion( "PDBeChem:TES") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:10438974") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:11786693") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:18900503") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:24498482") +AnnotationAssertion(Annotation( "Reaxys") "Reaxys:1915399") +AnnotationAssertion( "Wikipedia:Testosterone") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "17beta-hydroxyandrost-4-en-3-one") +AnnotationAssertion(Annotation( "PDBeChem") "TESTOSTERONE") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Testosterone") +AnnotationAssertion(Annotation( "UniProt") "testosterone") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "17beta-Hydroxy-4-androsten-3-one") +AnnotationAssertion(Annotation( "ChEBI") "17beta-hydroxy-4-androsten-3-one") +AnnotationAssertion(Annotation( "NIST_Chemistry_WebBook") "4-androsten-17beta-ol-3-one") +AnnotationAssertion(Annotation( "ChemIDplus") "Androderm") +AnnotationAssertion(Annotation( "ChemIDplus") "Testosteron") +AnnotationAssertion(Annotation( "ChemIDplus") Annotation( ) "testosterona") +AnnotationAssertion(Annotation( "ChemIDplus") Annotation( ) "testosterone") +AnnotationAssertion(Annotation( "ChemIDplus") Annotation( ) "testosteronum") +AnnotationAssertion( "CHEBI:17347") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "testosterone") +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (aldehyde) + +AnnotationAssertion( "A compound RC(=O)H, in which a carbonyl group is bonded to one hydrogen atom and to one R group.") +AnnotationAssertion( "0") +AnnotationAssertion( "CHOR") +AnnotationAssertion( "29.01800") +AnnotationAssertion( "29.00274") +AnnotationAssertion( "[H]C([*])=O") +AnnotationAssertion( "CHEBI:13432") +AnnotationAssertion( "CHEBI:13753") +AnnotationAssertion( "CHEBI:13805") +AnnotationAssertion( "CHEBI:13806") +AnnotationAssertion( "CHEBI:22291") +AnnotationAssertion( "CHEBI:2554") +AnnotationAssertion( "CHEBI:8750") +AnnotationAssertion( "KEGG:C00071") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Aldehyde") +AnnotationAssertion(Annotation( "ChEBI") "aldehyde") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "aldehyde") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "aldehydes") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "Aldehyd") +AnnotationAssertion(Annotation( "IUPAC") "RC(=O)H") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "RCHO") +AnnotationAssertion(Annotation( "ChEBI") "aldehido") +AnnotationAssertion(Annotation( "ChEBI") "aldehidos") +AnnotationAssertion(Annotation( "ChEBI") "aldehydes") +AnnotationAssertion(Annotation( "ChEBI") "aldehydum") +AnnotationAssertion(Annotation( "UniProt") "an aldehyde") +AnnotationAssertion( "CHEBI:17478") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "aldehyde") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (hydrogencarbonate) AnnotationAssertion( "The carbon oxoanion resulting from the removal of a proton from carbonic acid.") @@ -10198,6 +19354,47 @@ SubClassOf( ObjectSomeValuesFrom( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (geroprotector) + +AnnotationAssertion( "Any compound that supports healthy aging, slows the biological aging process, or extends lifespan.") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:23372317") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:28580190") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:30885572") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:33144142") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:33973253") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:34606237") +AnnotationAssertion( "Wikipedia:Geroprotector") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "anti-aging agent") +AnnotationAssertion(Annotation( "ChEBI") "anti-aging agents") +AnnotationAssertion(Annotation( "ChEBI") "anti-aging drug") +AnnotationAssertion(Annotation( "ChEBI") "anti-aging drugs") +AnnotationAssertion(Annotation( "ChEBI") "geroprotective agent") +AnnotationAssertion(Annotation( "ChEBI") "geroprotective agents") +AnnotationAssertion(Annotation( "ChEBI") "geroprotectors") +AnnotationAssertion( "CHEBI:176497") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "geroprotector") +SubClassOf( ) + +# Class: (ribonucleoside diphosphate) + +AnnotationAssertion( "0") +AnnotationAssertion( "C5H11O10P2R") +AnnotationAssertion( "293.083") +AnnotationAssertion( "292.98274") +AnnotationAssertion( "CHEBI:15046") +AnnotationAssertion( "CHEBI:26557") +AnnotationAssertion( "CHEBI:8845") +AnnotationAssertion( "KEGG:C03723") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Ribonucleoside diphosphate") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "ribonucleoside diphosphates") +AnnotationAssertion( "CHEBI:17668") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "ribonucleoside diphosphate") +SubClassOf( ) + # Class: (ceramide) AnnotationAssertion( "Ceramides (N-acyl-sphingoid bases) are a major subclass of sphingoid base derivatives with an amide-linked fatty acid. The fatty acids are typically saturated or monounsaturated with chain lengths from 14 to 26 carbon atoms; the presence of a hydroxyl group on carbon 2 is fairly common. Ceramides are generally precursors of more complex sphingolipids. In the illustrated generalised structure, R(1) = OH, OX (where X = acyl, glycosyl, phosphate, phosphonate, etc.), or H.") @@ -10241,6 +19438,69 @@ AnnotationAssertion( "donor") SubClassOf( ) +# Class: (butyrate) + +AnnotationAssertion( "A short-chain fatty acid anion that is the conjugate base of butyric acid, obtained by deprotonation of the carboxy group.") +AnnotationAssertion( "-1") +AnnotationAssertion( "C4H7O2") +AnnotationAssertion( "InChI=1S/C4H8O2/c1-2-3-4(5)6/h2-3H2,1H3,(H,5,6)/p-1") +AnnotationAssertion( "FERIUCNNQQJTOY-UHFFFAOYSA-M") +AnnotationAssertion( "87.09718") +AnnotationAssertion( "87.04515") +AnnotationAssertion( "CCCC([O-])=O") +AnnotationAssertion( "CHEBI:13924") +AnnotationAssertion( "CHEBI:22946") +AnnotationAssertion(Annotation( "Beilstein") "Beilstein:3601060") +AnnotationAssertion(Annotation( "ChemIDplus") "CAS:461-55-2") +AnnotationAssertion(Annotation( "Gmelin") "Gmelin:324289") +AnnotationAssertion( "KEGG:C00246") +AnnotationAssertion( "MetaCyc:BUTYRIC_ACID") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:17190852") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:7496326") +AnnotationAssertion(Annotation( "Reaxys") "Reaxys:3601060") +AnnotationAssertion(Annotation( "UM-BBD") "UM-BBD_compID:c0035") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "butanoate") +AnnotationAssertion(Annotation( "IUPAC") "butyrate") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "1-butanoate") +AnnotationAssertion(Annotation( "ChEBI") "1-butyrate") +AnnotationAssertion(Annotation( "ChEBI") "1-propanecarboxylate") +AnnotationAssertion(Annotation( "IUPAC") "CH3-[CH2]2-COO(-)") +AnnotationAssertion(Annotation( "ChEBI") "butanate") +AnnotationAssertion(Annotation( "ChEBI") "butanoate") +AnnotationAssertion(Annotation( "UniProt") "butanoate") +AnnotationAssertion(Annotation( "ChemIDplus") "butanoic acid, ion(1-)") +AnnotationAssertion(Annotation( "ChEBI") "n-butanoate") +AnnotationAssertion(Annotation( "ChemIDplus") "n-butyrate") +AnnotationAssertion(Annotation( "ChEBI") "propanecarboxylate") +AnnotationAssertion(Annotation( "ChEBI") "propylformate") +AnnotationAssertion( "CHEBI:17968") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "butyrate") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (ribonucleoside triphosphate) + +AnnotationAssertion( "0") +AnnotationAssertion( "C5H12O13P3R") +AnnotationAssertion( "373.063") +AnnotationAssertion( "372.94908") +AnnotationAssertion( "CHEBI:15047") +AnnotationAssertion( "CHEBI:26559") +AnnotationAssertion( "CHEBI:8846") +AnnotationAssertion( "KEGG:C03802") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Ribonucleoside triphosphate") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "ribonucleoside triphosphates") +AnnotationAssertion( "CHEBI:17972") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "ribonucleoside triphosphate") +SubClassOf( ) + # Class: (lipid) AnnotationAssertion( "'Lipids' is a loosely defined term for substances of biological origin that are soluble in nonpolar solvents. They consist of saponifiable lipids, such as glycerides (fats and oils) and phospholipids, as well as nonsaponifiable lipids, principally steroids.") @@ -10276,6 +19536,24 @@ AnnotationAssertion( "glycosaminoglycan") SubClassOf( ) +# Class: (hexose) + +AnnotationAssertion( "Any six-carbon monosaccharide which in its linear form contains either an aldehyde group at position 1 (aldohexose) or a ketone group at position 2 (ketohexose).") +AnnotationAssertion( "CHEBI:14399") +AnnotationAssertion( "CHEBI:24590") +AnnotationAssertion( "CHEBI:5709") +AnnotationAssertion( "GlyGen:G70994MS") +AnnotationAssertion( "GlyTouCan:G70994MS") +AnnotationAssertion( "KEGG:C00738") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Hexose") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "GlyTouCan") "WURCS=2.0/1,1,0/[axxxxh-1x_1-5_2*NCC/3=O]/1/") +AnnotationAssertion(Annotation( "ChEBI") "hexoses") +AnnotationAssertion( "CHEBI:18133") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "hexose") +SubClassOf( ) + # Class: (polysaccharide) AnnotationAssertion( "A biomacromolecule consisting of large numbers of monosaccharide residues linked glycosidically. This term is commonly used only for those containing more than ten monosaccharide residues.") @@ -10300,6 +19578,244 @@ SubClassOf( ) SubClassOf( ) +# Class: (glutamic acid) + +AnnotationAssertion( "An alpha-amino acid that is glutaric acid bearing a single amino substituent at position 2.") +AnnotationAssertion( "0") +AnnotationAssertion( "C5H9NO4") +AnnotationAssertion( "InChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)") +AnnotationAssertion( "WHUUTDBJXJRKMK-UHFFFAOYSA-N") +AnnotationAssertion( "147.12930") +AnnotationAssertion( "147.05316") +AnnotationAssertion( "NC(CCC(O)=O)C(O)=O") +AnnotationAssertion( "CHEBI:24314") +AnnotationAssertion( "CHEBI:5431") +AnnotationAssertion(Annotation( "Beilstein") "Beilstein:1723799") +AnnotationAssertion(Annotation( "ChemIDplus") "CAS:617-65-2") +AnnotationAssertion(Annotation( "KEGG COMPOUND") "CAS:617-65-2") +AnnotationAssertion(Annotation( "NIST Chemistry WebBook") "CAS:617-65-2") +AnnotationAssertion(Annotation( "Gmelin") "Gmelin:101971") +AnnotationAssertion( "KEGG:C00302") +AnnotationAssertion( "KEGG:D04341") +AnnotationAssertion( "KNApSAcK:C00001358") +AnnotationAssertion( "KNApSAcK:C00019577") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:15739367") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:17190852") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:24616376") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:24984001") +AnnotationAssertion(Annotation( "Reaxys") "Reaxys:1723799") +AnnotationAssertion( "Wikipedia:Glutamic_acid") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "2-aminopentanedioic acid") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Glutamic acid") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "glutamic acid") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "2-Aminoglutaric acid") +AnnotationAssertion(Annotation( "KEGG_DRUG") "DL-Glutamic acid") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "DL-Glutaminic acid") +AnnotationAssertion(Annotation( "ChEBI") "E") +AnnotationAssertion(Annotation( "ChEBI") "Glu") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Glutamate") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Glutaminic acid") +AnnotationAssertion(Annotation( "ChEBI") "Glutaminsaeure") +AnnotationAssertion( "CHEBI:18237") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "glutamic acid") +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (dopamine) + +AnnotationAssertion( "Catechol in which the hydrogen at position 4 is substituted by a 2-aminoethyl group.") +AnnotationAssertion( "0") +AnnotationAssertion( "C8H11NO2") +AnnotationAssertion( "InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2") +AnnotationAssertion( "VYFYYTLLBUKUHU-UHFFFAOYSA-N") +AnnotationAssertion( "153.17840") +AnnotationAssertion( "153.07898") +AnnotationAssertion( "NCCc1ccc(O)c(O)c1") +AnnotationAssertion( "CHEBI:11695") +AnnotationAssertion( "CHEBI:11930") +AnnotationAssertion( "CHEBI:14203") +AnnotationAssertion( "CHEBI:1764") +AnnotationAssertion( "CHEBI:23886") +AnnotationAssertion( "CHEBI:43686") +AnnotationAssertion(Annotation( "ChemIDplus") "CAS:51-61-6") +AnnotationAssertion( "DrugBank:DB00988") +AnnotationAssertion(Annotation( "DrugCentral") "Drug_Central:947") +AnnotationAssertion( "HMDB:HMDB0000073") +AnnotationAssertion( "KEGG:C03758") +AnnotationAssertion( "KEGG:D07870") +AnnotationAssertion( "KNApSAcK:C00001408") +AnnotationAssertion( "LINCS:LSM-4630") +AnnotationAssertion( "MetaCyc:DOPAMINE") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:10629745") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:11149432") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:9422813") +AnnotationAssertion(Annotation( "Reaxys") "Reaxys:1072822") +AnnotationAssertion( "Wikipedia:Dopamine") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "4-(2-aminoethyl)benzene-1,2-diol") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Dopamine") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "2-(3,4-Dihydroxyphenyl)ethylamine") +AnnotationAssertion(Annotation( "ChEBI") "2-(3,4-dihydroxyphenyl)ethylamine") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "3,4-Dihydroxyphenethylamine") +AnnotationAssertion(Annotation( "ChemIDplus") "3-Hydroxytyramine") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "4-(2-Aminoethyl)-1,2-benzenediol") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "4-(2-Aminoethyl)benzene-1,2-diol") +AnnotationAssertion(Annotation( "ChEBI") "4-(2-aminoethyl)-1,2-benzenediol") +AnnotationAssertion(Annotation( "ChemIDplus") "4-(2-aminoethyl)catechol") +AnnotationAssertion(Annotation( "ChemIDplus") "4-(2-aminoethyl)pyrocatechol") +AnnotationAssertion(Annotation( "DrugBank") "Deoxyepinephrine") +AnnotationAssertion(Annotation( "DrugBank") "Hydroxytyramin") +AnnotationAssertion(Annotation( "ChemIDplus") Annotation( ) "dopamina") +AnnotationAssertion(Annotation( "ChEBI") Annotation( ) "dopamine") +AnnotationAssertion(Annotation( "ChemIDplus") Annotation( ) "dopaminum") +AnnotationAssertion( "CHEBI:18243") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "dopamine") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (iron atom) + +AnnotationAssertion( "An iron group element atom that has atomic number 26.") +AnnotationAssertion( "0") +AnnotationAssertion( "Fe") +AnnotationAssertion( "InChI=1S/Fe") +AnnotationAssertion( "XEEYBQQBJWHFJM-UHFFFAOYSA-N") +AnnotationAssertion( "55.84500") +AnnotationAssertion( "55.93494") +AnnotationAssertion( "[Fe]") +AnnotationAssertion( "CHEBI:13322") +AnnotationAssertion( "CHEBI:24872") +AnnotationAssertion( "CHEBI:5974") +AnnotationAssertion(Annotation( "ChemIDplus") "CAS:7439-89-6") +AnnotationAssertion(Annotation( "KEGG COMPOUND") "CAS:7439-89-6") +AnnotationAssertion(Annotation( "NIST Chemistry WebBook") "CAS:7439-89-6") +AnnotationAssertion( "DrugBank:DB01592") +AnnotationAssertion( "HMDB:HMDB0015531") +AnnotationAssertion( "KEGG:C00023") +AnnotationAssertion(Annotation( "Reaxys") "Reaxys:4122945") +AnnotationAssertion( "WebElements:Fe") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "iron") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "IUPAC") "26Fe") +AnnotationAssertion(Annotation( "ChEBI") "Eisen") +AnnotationAssertion(Annotation( "IUPAC") "Fe") +AnnotationAssertion(Annotation( "UniProt") "Fe") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Iron") +AnnotationAssertion(Annotation( "ChEBI") "fer") +AnnotationAssertion(Annotation( "IUPAC") "ferrum") +AnnotationAssertion(Annotation( "ChEBI") "hierro") +AnnotationAssertion(Annotation( "ChEBI") "iron") +AnnotationAssertion( "CHEBI:18248") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "iron atom") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (ribonucleoside) + +AnnotationAssertion( "Any nucleoside where the sugar component is D-ribose.") +AnnotationAssertion( "0") +AnnotationAssertion( "C5H9O4R") +AnnotationAssertion( "133.123") +AnnotationAssertion( "133.05008") +AnnotationAssertion( "OC[C@H]1O[C@@H]([*])[C@H](O)[C@@H]1O") +AnnotationAssertion( "CHEBI:13014") +AnnotationAssertion( "CHEBI:13015") +AnnotationAssertion( "CHEBI:13685") +AnnotationAssertion( "CHEBI:21085") +AnnotationAssertion( "CHEBI:26560") +AnnotationAssertion( "CHEBI:4240") +AnnotationAssertion( "CHEBI:8844") +AnnotationAssertion( "KEGG:C00911") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Ribonucleoside") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "UniProt") "a ribonucleoside") +AnnotationAssertion(Annotation( "ChEBI") "ribonucleosides") +AnnotationAssertion( "CHEBI:18254") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "ribonucleoside") +SubClassOf( ) +SubClassOf( ) + +# Class: (nucleobase) + +AnnotationAssertion( "That part of DNA or RNA that may be involved in pairing.") +AnnotationAssertion( "CHEBI:13873") +AnnotationAssertion( "CHEBI:25598") +AnnotationAssertion( "CHEBI:2995") +AnnotationAssertion( "KEGG:C00701") +AnnotationAssertion( "Wikipedia:Nucleobase") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Base") +AnnotationAssertion(Annotation( "ChEBI") "nucleobases") +AnnotationAssertion( "CHEBI:18282") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "nucleobase") +SubClassOf( ) + +# Class: (histamine) + +AnnotationAssertion( "A member of the class of imidazoles that is 1H-imidazole substituted at position C-4 by a 2-aminoethyl group.") +AnnotationAssertion( "0") +AnnotationAssertion( "C5H9N3") +AnnotationAssertion( "InChI=1S/C5H9N3/c6-2-1-5-3-7-4-8-5/h3-4H,1-2,6H2,(H,7,8)") +AnnotationAssertion( "NTYJJOPFIAHURM-UHFFFAOYSA-N") +AnnotationAssertion( "111.14518") +AnnotationAssertion( "111.07965") +AnnotationAssertion( "NCCc1c[nH]cn1") +AnnotationAssertion( "CHEBI:14401") +AnnotationAssertion( "CHEBI:24596") +AnnotationAssertion( "CHEBI:43187") +AnnotationAssertion( "CHEBI:817") +AnnotationAssertion(Annotation( "Beilstein") "Beilstein:2012") +AnnotationAssertion(Annotation( "ChemIDplus") "CAS:51-45-6") +AnnotationAssertion(Annotation( "KEGG COMPOUND") "CAS:51-45-6") +AnnotationAssertion(Annotation( "NIST Chemistry WebBook") "CAS:51-45-6") +AnnotationAssertion(Annotation( "DrugCentral") "Drug_Central:1375") +AnnotationAssertion(Annotation( "Gmelin") "Gmelin:2968") +AnnotationAssertion( "HMDB:HMDB0000870") +AnnotationAssertion( "KEGG:C00388") +AnnotationAssertion( "KEGG:D08040") +AnnotationAssertion( "KNApSAcK:C00001414") +AnnotationAssertion( "MetaCyc:HISTAMINE") +AnnotationAssertion( "PDBeChem:HSM") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:16399866") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:19547708") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:19843401") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:22770225") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:24101735") +AnnotationAssertion(Annotation( "Reaxys") "Reaxys:2012") +AnnotationAssertion( "Wikipedia:Histamine") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "2-(1H-imidazol-4-yl)ethanamine") +AnnotationAssertion(Annotation( "PDBeChem") "HISTAMINE") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Histamine") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "1H-Imidazole-4-ethanamine") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "2-(4-Imidazolyl)ethylamine") +AnnotationAssertion( "CHEBI:18295") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "histamine") +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (alkane) AnnotationAssertion( "An acyclic branched or unbranched hydrocarbon having the general formula CnH2n+2, and therefore consisting entirely of hydrogen atoms and saturated carbon atoms.") @@ -10329,6 +19845,64 @@ AnnotationAssertion(rdfs:label "alk SubClassOf( ) SubClassOf( ) +# Class: ((R)-noradrenaline) + +AnnotationAssertion( "The R-enantiomer of noradrenaline.") +AnnotationAssertion( "0") +AnnotationAssertion( "C8H11NO3") +AnnotationAssertion( "InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2/t8-/m0/s1") +AnnotationAssertion( "SFLSHLFXELFNJZ-QMMMGPOBSA-N") +AnnotationAssertion( "169.17780") +AnnotationAssertion( "169.07389") +AnnotationAssertion( "NC[C@H](O)c1ccc(O)c(O)c1") +AnnotationAssertion( "CHEBI:1") +AnnotationAssertion( "CHEBI:14668") +AnnotationAssertion( "CHEBI:25592") +AnnotationAssertion( "CHEBI:258884") +AnnotationAssertion( "CHEBI:43725") +AnnotationAssertion(Annotation( "Beilstein") "Beilstein:2804840") +AnnotationAssertion(Annotation( "ChemIDplus") "Beilstein:4231961") +AnnotationAssertion(Annotation( "ChemIDplus") "CAS:51-41-2") +AnnotationAssertion(Annotation( "KEGG COMPOUND") "CAS:51-41-2") +AnnotationAssertion( "DrugBank:DB00368") +AnnotationAssertion(Annotation( "DrugCentral") "Drug_Central:1960") +AnnotationAssertion( "HMDB:HMDB0000216") +AnnotationAssertion( "KEGG:C00547") +AnnotationAssertion( "KEGG:D00076") +AnnotationAssertion( "KNApSAcK:C00001424") +AnnotationAssertion( "PDBeChem:LNR") +AnnotationAssertion(Annotation( "Reaxys") "Reaxys:2804840") +AnnotationAssertion( "Wikipedia:Norepinephrine") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "4-[(1R)-2-amino-1-hydroxyethyl]benzene-1,2-diol") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChemIDplus") "(-)-arterenol") +AnnotationAssertion(Annotation( "IUPHAR") "(-)-noradrenaline") +AnnotationAssertion(Annotation( "ChemIDplus") "(-)-norepinephrine") +AnnotationAssertion(Annotation( "ChemIDplus") "(R)-(-)-norepinephrine") +AnnotationAssertion(Annotation( "ChemIDplus") "(R)-4-(2-amino-1-hydroxyethyl)-1,2-benzenediol") +AnnotationAssertion(Annotation( "ChemIDplus") "(R)-norepinephrine") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "4-[(1R)-2-Amino-1-hydroxyethyl]-1,2-benzenediol") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Arterenol") +AnnotationAssertion(Annotation( "PDBeChem") "L-NOREPINEPHRINE") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "L-Noradrenaline") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Noradrenaline") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Norepinephrine") +AnnotationAssertion(Annotation( "ChEBI") Annotation( ) "norepinefrina") +AnnotationAssertion(Annotation( "ChemIDplus") Annotation( ) "norepinephrine") +AnnotationAssertion(Annotation( "WHO_MedNet") Annotation( ) "norepinephrine") +AnnotationAssertion(Annotation( "ChEBI") Annotation( ) "norepinephrinum") +AnnotationAssertion( "CHEBI:18357") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "(R)-noradrenaline") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (phosphate(3-)) AnnotationAssertion( "A phosphate ion that is the conjugate base of hydrogenphosphate.") @@ -10377,6 +19951,53 @@ AnnotationAssertion(rdfs:label "in SubClassOf( ) SubClassOf( ) +# Class: (4-[1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol) + +AnnotationAssertion( "A catecholamine in which the aminoethyl side-chain is hydroxy-substituted at C-1 and methylated on nitrogen.") +AnnotationAssertion( "0") +AnnotationAssertion( "C9H13NO3") +AnnotationAssertion( "InChI=1S/C9H13NO3/c1-10-5-9(13)6-2-3-7(11)8(12)4-6/h2-4,9-13H,5H2,1H3") +AnnotationAssertion( "UCTWMZQNUQWSLP-UHFFFAOYSA-N") +AnnotationAssertion( "183.207") +AnnotationAssertion( "183.08954") +AnnotationAssertion( "CNCC(O)C1=CC(O)=C(O)C=C1") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "4-[1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion( "CHEBI:194548") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "4-[1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol") +SubClassOf( ) + +# Class: (5beta-cholane) + +AnnotationAssertion( "0") +AnnotationAssertion( "C24H42") +AnnotationAssertion( "InChI=1S/C24H42/c1-5-8-17(2)20-12-13-21-19-11-10-18-9-6-7-15-23(18,3)22(19)14-16-24(20,21)4/h17-22H,5-16H2,1-4H3/t17-,18+,19+,20-,21+,22+,23+,24-/m1/s1") +AnnotationAssertion( "QSHQKIURKJITMZ-OBUPQJQESA-N") +AnnotationAssertion( "330.59028") +AnnotationAssertion( "330.32865") +AnnotationAssertion( "[H][C@@]12CCCC[C@]1(C)[C@@]1([H])CC[C@]3(C)[C@]([H])(CC[C@@]3([H])[C@]1([H])CC2)[C@H](C)CCC") +AnnotationAssertion(Annotation( "Beilstein") "Beilstein:2048472") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "5beta-cholane") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion( "CHEBI:20664") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "5beta-cholane") +SubClassOf( ) + +# Class: (6-aminopurines) + +AnnotationAssertion( "Any compound having 6-aminopurine (adenine) as part of its structure.") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:1646334") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:18524423") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:7342604") +AnnotationAssertion(Annotation( "ChEBI") "6-aminopurines") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion( "CHEBI:20706") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "6-aminopurines") +SubClassOf( ) + # Class: (N-acylglucosamine) AnnotationAssertion(Annotation( "ChEBI") "N-acylglucosamine") @@ -10398,6 +20019,31 @@ AnnotationAssertion( "N-acyl-hexosamine") SubClassOf( ) +# Class: (N-glycosyl compound) + +AnnotationAssertion( "A glycosyl compound arising formally from the elimination of water from a glycosidic hydroxy group and an H atom bound to a nitrogen atom, thus creating a C-N bond.") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "glycosylamine") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "N-glycoside") +AnnotationAssertion(Annotation( "ChEBI") "N-glycosides") +AnnotationAssertion(Annotation( "ChEBI") "N-glycosyl compounds") +AnnotationAssertion(Annotation( "IUPAC") "glycosylamines") +AnnotationAssertion( "CHEBI:21731") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "N-glycosyl compound") +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (acetamides) + +AnnotationAssertion( "Compounds with the general formula RNHC(=O)CH3.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion( "CHEBI:22160") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "acetamides") +SubClassOf( ) + # Class: (acyl group) AnnotationAssertion( "An organic group formed by removing one or more hydroxy groups from an oxoacid that has the general structure RkE(=O)l(OH)m (l =/= 0). Although the term is almost always applied to organic compounds, with carboxylic acid as the oxoacid, acyl groups can in principle be derived from other types of acids such as sulfonic acids or phosphonic acids.") @@ -10412,6 +20058,27 @@ AnnotationAssertion( "acyl group") SubClassOf( ) +# Class: (adenosine phosphate) + +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "adenosine phosphates") +AnnotationAssertion( "CHEBI:22256") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "adenosine phosphate") +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (adenosines) + +AnnotationAssertion( "Any purine ribonucleoside that is a derivative of adenosine.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion( "CHEBI:22260") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "adenosines") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (alkaline earth metal atom) AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "alkaline earth metals") @@ -10450,6 +20117,22 @@ SubClassOf( ) SubClassOf( ) +# Class: (alkaloid) + +AnnotationAssertion( "Any of the naturally occurring, basic nitrogen compounds (mostly heterocyclic) occurring mostly in the plant kingdom, but also found in bacteria, fungi, and animals. By extension, certain neutral compounds biogenetically related to basic alkaloids are also classed as alkaloids. Amino acids, peptides, proteins, nucleotides, nucleic acids, amino sugars and antibiotics are not normally regarded as alkaloids. Compounds in which the nitrogen is exocyclic (dopamine, mescaline, serotonin, etc.) are usually classed as amines rather than alkaloids.") +AnnotationAssertion( "Wikipedia:Alkaloid") +AnnotationAssertion(Annotation( "ChEBI") "Alkaloid") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "alkaloids") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "Alkaloide") +AnnotationAssertion(Annotation( "ChEBI") "alcaloide") +AnnotationAssertion(Annotation( "ChEBI") "alcaloides") +AnnotationAssertion( "CHEBI:22315") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "alkaloid") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (aminoglycan) AnnotationAssertion( "chebi_ontology") @@ -10460,6 +20143,16 @@ AnnotationAssertion(rdfs:label "ami SubClassOf( ) SubClassOf( ) +# Class: (aminopurine) + +AnnotationAssertion( "Any purine having at least one amino substituent.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "aminopurines") +AnnotationAssertion( "CHEBI:22527") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "aminopurine") +SubClassOf( ) + # Class: (anion) AnnotationAssertion( "A monoatomic or polyatomic species having one or more elementary charges of the electron.") @@ -10505,6 +20198,17 @@ AnnotationAssertion( "base") SubClassOf( ) +# Class: (benzopyrrole) + +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "benzopyrroles") +AnnotationAssertion( "CHEBI:22728") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "benzopyrrole") +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + # Class: (bile salt) AnnotationAssertion( "A sodium salt of the conjugate of any bile acid with either glycine or taurine.") @@ -10728,6 +20432,27 @@ AnnotationAssertion( "cyclic peptide") SubClassOf( ) +# Class: (diazole) + +AnnotationAssertion( "An azole that is either one of a pair of heterocyclic organic compounds comprising three carbon atoms and two nitrogen atoms arranged in a ring.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "diazoles") +AnnotationAssertion( "CHEBI:23677") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "diazole") +SubClassOf( ) + +# Class: (({[(2R,3S,4R,5R)-3,4-dihydroxy-5-(9H-purin-9-yl)oxolan-2-yl]methyl phosphonato}oxy)(phosphonatooxy)phosphinate) + +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion( "CHEBI:237958") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "({[(2R,3S,4R,5R)-3,4-dihydroxy-5-(9H-purin-9-yl)oxolan-2-yl]methyl phosphonato}oxy)(phosphonatooxy)phosphinate") +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (drug) AnnotationAssertion( "Any substance which when absorbed into a living organism may modify one or more of its functions. The term is generally accepted for a substance taken for a therapeutic purpose, but is also commonly used for abused substances.") @@ -10765,6 +20490,16 @@ AnnotationAssertion(rdfs:label "enz SubClassOf( ) SubClassOf( ) +# Class: (glucocorticoid) + +AnnotationAssertion( "Glucocorticoids are a class of steroid hormones that regulate a variety of physiological processes, in particular control of the concentration of glucose in blood.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "glucocorticoids") +AnnotationAssertion( "CHEBI:24261") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "glucocorticoid") +SubClassOf( ) + # Class: (glucosamines) AnnotationAssertion( "Any hexosamine that is glucose in which at least one of the hydroxy groups has been replaced by an amino group.") @@ -10774,6 +20509,51 @@ AnnotationAssertion( "glucosamines") SubClassOf( ) +# Class: (glutamine family amino acid) + +AnnotationAssertion( "An L-alpha-amino acid which is L-glutamic acid or any of the essential amino acids biosynthesised from it (glutamine, proline and arginine). A closed class.") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:20716061") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "glutamine family amino acids") +AnnotationAssertion( "CHEBI:24318") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "glutamine family amino acid") +SubClassOf( ) +SubClassOf( ) + +# Class: (EC 6.3.1.2 (glutamate--ammonia ligase) inhibitor) + +AnnotationAssertion( "An EC 6.3.* (C-N bond-forming ligase) inhibitor that interferes with the action of glutamate--ammonia ligase (EC 6.3.1.2).") +AnnotationAssertion( "Wikipedia:Glutamine_synthetase") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "EC 6.3.1.2 (glutamate--ammonia ligase) inhibitors") +AnnotationAssertion(Annotation( "ChEBI") "EC 6.3.1.2 inhibitor") +AnnotationAssertion(Annotation( "ChEBI") "EC 6.3.1.2 inhibitors") +AnnotationAssertion(Annotation( "ChEBI") "L-glutamate:ammonia ligase (ADP-forming) inhibitor") +AnnotationAssertion(Annotation( "ChEBI") "L-glutamate:ammonia ligase (ADP-forming) inhibitors") +AnnotationAssertion(Annotation( "ChEBI") "L-glutamine synthetase inhibitor") +AnnotationAssertion(Annotation( "ChEBI") "L-glutamine synthetase inhibitors") +AnnotationAssertion(Annotation( "ChEBI") "glutamate--ammonia ligase (EC 6.3.1.2) inhibitor") +AnnotationAssertion(Annotation( "ChEBI") "glutamate--ammonia ligase (EC 6.3.1.2) inhibitors") +AnnotationAssertion(Annotation( "ChEBI") "glutamate--ammonia ligase inhibitor") +AnnotationAssertion(Annotation( "ChEBI") "glutamate--ammonia ligase inhibitors") +AnnotationAssertion(Annotation( "ChEBI") "glutamine synthetase inhibitor") +AnnotationAssertion(Annotation( "ChEBI") "glutamine synthetase inhibitors") +AnnotationAssertion(Annotation( "ChEBI") "glutamylhydroxamic synthetase inhibitor") +AnnotationAssertion(Annotation( "ChEBI") "glutamylhydroxamic synthetase inhibitors") +AnnotationAssertion( "CHEBI:24319") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "EC 6.3.1.2 (glutamate--ammonia ligase) inhibitor") +SubClassOf( ) + +# Class: (glycogens) + +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion( "CHEBI:24384") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "glycogens") +SubClassOf( ) + # Class: (glycosphingolipid) AnnotationAssertion( "A glycosphingolipid is a glycolipid that is a carbohydrate-containing derivative of a sphingoid or ceramide. It is understood that the carbohydrate residue is attached by a glycosidic linkage to O-1 of the sphingoid.") @@ -10905,6 +20685,36 @@ SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (hydroxy-5beta-cholanic acid) + +AnnotationAssertion( "Any member of the class of 5beta-cholanic acids carrying at least one hydroxy group at unspecified position.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "hydroxy-5beta-cholanic acids") +AnnotationAssertion( "CHEBI:24663") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "hydroxy-5beta-cholanic acid") +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (imidazoles) + +AnnotationAssertion( "A five-membered organic heterocycle containing two nitrogen atoms at positions 1 and 3, or any of its derivatives; compounds containing an imidazole skeleton.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion( "CHEBI:24780") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "imidazoles") +SubClassOf( ) + +# Class: (indoles) + +AnnotationAssertion( "Any compound containing an indole skeleton.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion( "CHEBI:24828") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "indoles") +SubClassOf( ) + # Class: (oxoacid) AnnotationAssertion( "A compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons).") @@ -11023,6 +20833,34 @@ AnnotationAssertion( "ion") SubClassOf( ) +# Class: (iron molecular entity) + +AnnotationAssertion(Annotation( "ChEBI") "iron molecular entity") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "iron compounds") +AnnotationAssertion(Annotation( "ChEBI") "iron molecular entities") +AnnotationAssertion( "CHEBI:24873") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "iron molecular entity") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (iron cation) + +AnnotationAssertion( "Fe") +AnnotationAssertion( "55.845") +AnnotationAssertion( "55.93494") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "iron cation") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "UniProt") "Fe cation") +AnnotationAssertion(Annotation( "ChEBI") "iron cations") +AnnotationAssertion( "CHEBI:24875") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "iron cation") +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (isoprenoid) AnnotationAssertion( "Any lipid formally derived from isoprene (2-methylbuta-1,3-diene), the skeleton of which can generally be discerned in repeated occurrence in the molecule. The skeleton of isoprenoids may differ from strict additivity of isoprene units by loss or shift of a fragment, commonly a methyl group. The class includes both hydrocarbons and oxygenated derivatives.") @@ -11085,6 +20923,28 @@ AnnotationAssertion(rdfs:label "met SubClassOf( ) SubClassOf( ) +# Class: (mineralocorticoid) + +AnnotationAssertion( "Mineralocorticoids are a class of steroid hormones that regulate water and electrolyte metabolism.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "mineralocorticoids") +AnnotationAssertion( "CHEBI:25354") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "mineralocorticoid") +SubClassOf( ) + +# Class: (elemental molecule) + +AnnotationAssertion( "A molecule all atoms of which have the same atomic number.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "homoatomic molecule") +AnnotationAssertion(Annotation( "ChEBI") "homoatomic molecules") +AnnotationAssertion( "CHEBI:25362") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "elemental molecule") +SubClassOf( ) +SubClassOf( ) + # Class: (molecule) AnnotationAssertion( "Any polyatomic entity that is an electrically neutral entity consisting of more than one atom.") @@ -11099,6 +20959,29 @@ AnnotationAssertion( "molecule") SubClassOf( ) +# Class: (monoamine molecular messenger) + +AnnotationAssertion( "A group of neurotransmitters and neuromodulators that contain one amino group that is connected to an aromatic ring by ethylene group (-CH2-CH2-). Monoamines are derived from the aromatic amino acids phenylalanine, tyrosine, histidine and tryptophan.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "monamines") +AnnotationAssertion(Annotation( "ChEBI") "monoamines") +AnnotationAssertion( "CHEBI:25375") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "monoamine molecular messenger") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (monocarboxylic acid) + +AnnotationAssertion( "An oxoacid containing a single carboxy group.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "monocarboxylic acids") +AnnotationAssertion( "CHEBI:25384") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "monocarboxylic acid") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (monoatomic monocation) AnnotationAssertion( "+1") @@ -11173,6 +21056,32 @@ AnnotationAssertion( "nonmetal atom") SubClassOf( ) +# Class: (nucleoside phosphate) + +AnnotationAssertion( "A nucleobase-containing molecular entity that is a nucleoside in which one or more of the sugar hydroxy groups has been converted into a mono- or poly-phosphate. The term includes both nucleotides and non-nucleotide nucleoside phosphates.") +AnnotationAssertion( "KEGG:C01329") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "NMP") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Nucleoside monophosphate") +AnnotationAssertion(Annotation( "ChEBI") "nucleoside phosphates") +AnnotationAssertion( "CHEBI:25608") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "nucleoside phosphate") +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (organic heteromonocyclic compound) + +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "organic heteromonocyclic compounds") +AnnotationAssertion( "CHEBI:25693") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "organic heteromonocyclic compound") +SubClassOf( ) +SubClassOf( ) + # Class: (organic anion) AnnotationAssertion( "Any organic ion with a net negative charge.") @@ -11307,6 +21216,28 @@ AnnotationAssertion(rdfs:label "oxy SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (aldopentose phosphate) + +AnnotationAssertion(Annotation( "ChEBI") "aldopentose phosphate") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "aldopentose phosphates") +AnnotationAssertion( "CHEBI:25900") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "aldopentose phosphate") +SubClassOf( ) +SubClassOf( ) + +# Class: (pentose) + +AnnotationAssertion( "A five-carbon monosaccharide which in its linear form contains either an aldehyde group at position 1 (aldopentose) or a ketone group at position 2 (ketopentose).") +AnnotationAssertion(Annotation( "ChEBI") "pentose") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "pentoses") +AnnotationAssertion( "CHEBI:25901") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "pentose") +SubClassOf( ) + # Class: (peptide hormone) AnnotationAssertion( "Any peptide with hormonal activity in animals, whether endocrine, neuroendocrine, or paracrine.") @@ -11415,6 +21346,28 @@ AnnotationAssertion( "biological pigment") SubClassOf( ) +# Class: (polar amino acid) + +AnnotationAssertion( "Any amino acid whose side chain is capable of forming one or more hydrogen bonds.") +AnnotationAssertion( "0") +AnnotationAssertion( "C2H4NO2R") +AnnotationAssertion( "74.059") +AnnotationAssertion( "74.02420") +AnnotationAssertion( "OC(C(*)N)=O") +AnnotationAssertion( "CHEBI:8283") +AnnotationAssertion( "MetaCyc:Polar-amino-acids") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:12016058") +AnnotationAssertion(Annotation( "ChEBI") "polar amino acid") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "polar amino acids") +AnnotationAssertion(Annotation( "ChEBI") "polar amino-acid") +AnnotationAssertion(Annotation( "ChEBI") "polar amino-acids") +AnnotationAssertion( "CHEBI:26167") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "polar amino acid") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (porphyrins) AnnotationAssertion( "Natural pigments containing a fundamental skeleton of four pyrrole nuclei united through the alpha-positions by four methine groups to form a macrocyclic structure.") @@ -11427,6 +21380,127 @@ AnnotationAssertion(rdfs:label "por SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (purine nucleobase) + +AnnotationAssertion( "A nucleobase whose skeleton is derived from purine.") +AnnotationAssertion( "0") +AnnotationAssertion( "C5H3N4R2") +AnnotationAssertion( "119.104") +AnnotationAssertion( "119.03577") +AnnotationAssertion( "C1(NC(=NC=2NC=NC12)*)=*") +AnnotationAssertion( "KEGG:C15587") +AnnotationAssertion(Annotation( "ChEBI") "purine nucleobase") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "UniProt") "a purine nucleobase") +AnnotationAssertion(Annotation( "ChEBI") "purine bases") +AnnotationAssertion(Annotation( "ChEBI") "purine nucleobases") +AnnotationAssertion( "CHEBI:26386") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "purine nucleobase") +SubClassOf( ) +SubClassOf( ) + +# Class: (purine nucleoside diphosphate) + +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "purine nucleoside diphosphates") +AnnotationAssertion( "CHEBI:26391") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "purine nucleoside diphosphate") +SubClassOf( ) + +# Class: (purine nucleoside triphosphate) + +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "purine nucleoside triphosphates") +AnnotationAssertion( "CHEBI:26393") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "purine nucleoside triphosphate") +SubClassOf( ) + +# Class: (purine nucleoside) + +AnnotationAssertion(Annotation( "ChEBI") "purine nucleoside") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "purine nucleosides") +AnnotationAssertion( "CHEBI:26394") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "purine nucleoside") +SubClassOf( ) +SubClassOf( ) + +# Class: (purine nucleotide) + +AnnotationAssertion( "Any nucleotide that has a purine nucleobase.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "purine nucleotides") +AnnotationAssertion( "CHEBI:26395") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "purine nucleotide") +SubClassOf( ) +SubClassOf( ) + +# Class: (purine ribonucleoside diphosphate) + +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "purine ribonucleoside diphosphates") +AnnotationAssertion( "CHEBI:26396") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "purine ribonucleoside diphosphate") +SubClassOf( ) +SubClassOf( ) + +# Class: (purine ribonucleoside triphosphate) + +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "purine ribonucleoside triphosphates") +AnnotationAssertion( "CHEBI:26398") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "purine ribonucleoside triphosphate") +SubClassOf( ) +SubClassOf( ) + +# Class: (purine ribonucleoside) + +AnnotationAssertion( "A ribonucleoside that has a purine moiety as the nucleobase (the R group in the illustration).") +AnnotationAssertion( "0") +AnnotationAssertion( "C5H9O4R") +AnnotationAssertion( "133.123") +AnnotationAssertion( "133.05008") +AnnotationAssertion( "*[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "purine ribonucleosides") +AnnotationAssertion( "CHEBI:26399") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "purine ribonucleoside") +SubClassOf( ) +SubClassOf( ) + +# Class: (purine ribonucleotide) + +AnnotationAssertion( "Any ribonucleotide that has a purine nucleobase.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "purine ribonucleotides") +AnnotationAssertion( "CHEBI:26400") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "purine ribonucleotide") +SubClassOf( ) +SubClassOf( ) + +# Class: (purines) + +AnnotationAssertion( "A class of imidazopyrimidines that consists of purine and its substituted derivatives.") +AnnotationAssertion( "0") +AnnotationAssertion( "C5N4R7") +AnnotationAssertion( "116.080") +AnnotationAssertion( "116.01230") +AnnotationAssertion( "CHEBI:13678") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion( "CHEBI:26401") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "purines") +SubClassOf( ) + # Class: (quaternary nitrogen compound) AnnotationAssertion( "A nitrogen molecular entity that is electronically neutral but which contains a quaternary nitrogen.") @@ -11437,6 +21511,42 @@ AnnotationAssertion(rdfs:label "qua SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (ribonucleotide) + +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "ribonucleotides") +AnnotationAssertion( "CHEBI:26561") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "ribonucleotide") +SubClassOf( ) +SubClassOf( ) + +# Class: (ribose phosphate) + +AnnotationAssertion(Annotation( "ChEBI") "ribose phosphate") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "ribose phosphates") +AnnotationAssertion( "CHEBI:26562") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "ribose phosphate") +SubClassOf( ) + +# Class: (saturated fatty acid) + +AnnotationAssertion( "Any fatty acid containing no carbon to carbon multiple bonds. Known to produce adverse biological effects when ingested to excess.") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:16492686") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:19763019") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:20237329") +AnnotationAssertion(Annotation( "ChEBI") "saturated fatty acid") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "SFA") +AnnotationAssertion(Annotation( "ChEBI") "SFAs") +AnnotationAssertion(Annotation( "ChEBI") "saturated fatty acids") +AnnotationAssertion( "CHEBI:26607") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "saturated fatty acid") +SubClassOf( ) + # Class: (sesquiterpenoid) AnnotationAssertion( "Any terpenoid derived from a sesquiterpene. The term includes compounds in which the C15 skeleton of the parent sesquiterpene has been rearranged or modified by the removal of one or more skeletal atoms (generally methyl groups).") @@ -11450,6 +21560,28 @@ AnnotationAssertion(rdfs:label "ses SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (short-chain fatty acid) + +AnnotationAssertion( "An aliphatic monocarboxylic acid with a chain length of less than C6. If any non-hydrocarbon substituent is present, the compound is not normally regarded as a short-chain fatty acid.") +AnnotationAssertion( "0") +AnnotationAssertion( "CH2OR") +AnnotationAssertion( "45.017") +AnnotationAssertion( "44.99765") +AnnotationAssertion( "OC([*])=O") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:16633129") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:16870803") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:18203540") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:20148677") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "SCFA") +AnnotationAssertion(Annotation( "ChEBI") "SCFAs") +AnnotationAssertion(Annotation( "ChEBI") "short-chain fatty acids") +AnnotationAssertion( "CHEBI:26666") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "short-chain fatty acid") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (sodium atom) AnnotationAssertion( "0") @@ -11515,6 +21647,34 @@ SubClassOf( ) SubClassOf( ) +# Class: (steroid hormone) + +AnnotationAssertion( "Any steroid that acts as hormone.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "Steroidhormon") +AnnotationAssertion(Annotation( "ChEBI") "Steroidhormone") +AnnotationAssertion(Annotation( "ChEBI") "hormona esteroide") +AnnotationAssertion(Annotation( "ChEBI") "hormonas esteroideas") +AnnotationAssertion(Annotation( "ChEBI") "hormone steroide") +AnnotationAssertion(Annotation( "ChEBI") "hormones steroides") +AnnotationAssertion(Annotation( "ChEBI") "steroid hormones") +AnnotationAssertion( "CHEBI:26764") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "steroid hormone") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (carbohydrate phosphate) + +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "carbohydrate phosphates") +AnnotationAssertion( "CHEBI:26816") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "carbohydrate phosphate") +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + # Class: (sulfuric ester) AnnotationAssertion( "An ester of an alcohol and sulfuric acid.") @@ -11661,6 +21821,16 @@ AnnotationAssertion(rdfs:label "ter SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (oxolanes) + +AnnotationAssertion( "Any oxacycle having an oxolane (tetrahydrofuran) skeleton.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion( "CHEBI:26912") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "oxolanes") +SubClassOf( ) +SubClassOf( ) + # Class: (tetrapyrrole) AnnotationAssertion( "A natural pigment containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next.") @@ -11688,6 +21858,58 @@ AnnotationAssertion(rdfs:label "tet SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (micronutrient) + +AnnotationAssertion( "Any nutrient required in small quantities by organisms throughout their life in order to orchestrate a range of physiological functions.") +AnnotationAssertion( "Wikipedia:Micronutrient") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "micronutrients") +AnnotationAssertion(Annotation( "ChEBI") "trace elements") +AnnotationAssertion( "CHEBI:27027") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "micronutrient") +SubClassOf( ) + +# Class: (transition element atom) + +AnnotationAssertion( "An element whose atom has an incomplete d sub-shell, or which can give rise to cations with an incomplete d sub-shell.") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "transition element") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "Uebergangselement") +AnnotationAssertion(Annotation( "ChEBI") "Uebergangsmetalle") +AnnotationAssertion(Annotation( "ChEBI") "metal de transicion") +AnnotationAssertion(Annotation( "ChEBI") "metal de transition") +AnnotationAssertion(Annotation( "ChEBI") "metales de transicion") +AnnotationAssertion(Annotation( "ChEBI") "metaux de transition") +AnnotationAssertion(Annotation( "ChEBI") "transition element") +AnnotationAssertion(Annotation( "ChEBI") "transition elements") +AnnotationAssertion(Annotation( "ChEBI") "transition metal") +AnnotationAssertion(Annotation( "ChEBI") "transition metals") +AnnotationAssertion( "CHEBI:27081") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "transition element atom") +SubClassOf( ) + +# Class: (tryptamines) + +AnnotationAssertion( "Tryptamine and its substitution derivatives.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion( "CHEBI:27162") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "tryptamines") +SubClassOf( ) + +# Class: (organic heterobicyclic compound) + +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "heterobicyclic compounds") +AnnotationAssertion(Annotation( "ChEBI") "organic heterobicyclic compounds") +AnnotationAssertion( "CHEBI:27171") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "organic heterobicyclic compound") +SubClassOf( ) +SubClassOf( ) + # Class: (univalent carboacyl group) AnnotationAssertion( "A univalent carboacyl group is a group formed by loss of OH from the carboxy group of a carboxylic acid.") @@ -11763,6 +21985,57 @@ SubClassOf( ObjectSomeValuesFrom( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (aldosterone) + +AnnotationAssertion( "A pregnane-based steroidal hormone produced by the outer-section (zona glomerulosa) of the adrenal cortex in the adrenal gland, and acts on the distal tubules and collecting ducts of the kidney to cause the conservation of sodium, secretion of potassium, increased water retention, and increased blood pressure. The overall effect of aldosterone is to increase reabsorption of ions and water in the kidney.") +AnnotationAssertion( "0") +AnnotationAssertion( "C21H28O5") +AnnotationAssertion( "InChI=1S/C21H28O5/c1-20-7-6-13(24)8-12(20)2-3-14-15-4-5-16(18(26)10-22)21(15,11-23)9-17(25)19(14)20/h8,11,14-17,19,22,25H,2-7,9-10H2,1H3/t14-,15-,16+,17-,19+,20-,21+/m0/s1") +AnnotationAssertion( "PQSUYGKTWSAVDQ-ZVIOFETBSA-N") +AnnotationAssertion( "360.44400") +AnnotationAssertion( "360.19367") +AnnotationAssertion( "[H][C@@]1(CC[C@@]2([H])[C@]3([H])CCC4=CC(=O)CC[C@]4(C)[C@@]3([H])[C@@H](O)C[C@]12C=O)C(=O)CO") +AnnotationAssertion( "CHEBI:22306") +AnnotationAssertion( "CHEBI:2563") +AnnotationAssertion( "CHEBI:40919") +AnnotationAssertion(Annotation( "ChemIDplus") "Beilstein:3224996") +AnnotationAssertion(Annotation( "ChemIDplus") "CAS:52-39-1") +AnnotationAssertion(Annotation( "KEGG COMPOUND") "CAS:52-39-1") +AnnotationAssertion(Annotation( "NIST Chemistry WebBook") "CAS:52-39-1") +AnnotationAssertion( "DrugBank:DB04630") +AnnotationAssertion(Annotation( "DrugCentral") "Drug_Central:111") +AnnotationAssertion( "HMDB:HMDB0000037") +AnnotationAssertion( "KEGG:C01780") +AnnotationAssertion( "LINCS:LSM-42770") +AnnotationAssertion(Annotation( "LIPID MAPS") "LIPID_MAPS_instance:LMST02030026") +AnnotationAssertion( "PDBeChem:AS4") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:10438974") +AnnotationAssertion(Annotation( "Reaxys") "Reaxys:3224996") +AnnotationAssertion( "Wikipedia:Aldosterone") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "11beta,21-dihydroxy-3,20-dioxopregn-4-en-18-al") +AnnotationAssertion(Annotation( "PDBeChem") "ALDOSTERONE") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Aldosterone") +AnnotationAssertion(Annotation( "UniProt") "aldosterone") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "NIST_Chemistry_WebBook") "(+)-aldosterone") +AnnotationAssertion(Annotation( "NIST_Chemistry_WebBook") "(11beta)-11,21-dihydroxy-3,20-dioxopregn-4-en-18-al") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "11beta,21-Dihydroxy-3,20-dioxo-4-pregnen-18-al") +AnnotationAssertion( "CHEBI:27584") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "aldosterone") +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (carbon atom) AnnotationAssertion( "0") @@ -11796,6 +22069,31 @@ SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (glycogen) + +AnnotationAssertion( "A polydisperse, highly branched glucan composed of chains of D-glucopyranose residues in alpha(1->4) glycosidic linkage, joined together by alpha(1->6) glycosidic linkages. A small number of alpha(1->3) glycosidic linkages and some cumulative alpha(1->6) links also may occur. The branches in glycogen typically contain 8 to 12 glucose residues.") +AnnotationAssertion( "CHEBI:24379") +AnnotationAssertion( "CHEBI:5466") +AnnotationAssertion(Annotation( "ChemIDplus") "CAS:9005-79-2") +AnnotationAssertion(Annotation( "KEGG COMPOUND") "CAS:9005-79-2") +AnnotationAssertion( "GlyGen:G99991IU") +AnnotationAssertion( "GlyTouCan:G99991IU") +AnnotationAssertion( "HMDB:HMDB0000757") +AnnotationAssertion( "KEGG:C00182") +AnnotationAssertion( "MetaCyc:CPD0-971") +AnnotationAssertion( "Wikipedia:Glycogen") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Glycogen") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "GlyTouCan") "WURCS=2.0/1,4,3/[a2122h-1a_1-5]/1-1-1-1/a4-b1_b4-c1_b6-d1") +AnnotationAssertion(Annotation( "ChemIDplus") "animal starch") +AnnotationAssertion(Annotation( "ChemIDplus") "liver starch") +AnnotationAssertion( "CHEBI:28087") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "glycogen") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (alpha-carotene) AnnotationAssertion( "A cyclic carotene with a beta- and an epsilon-ring at opposite ends respectively.") @@ -11904,6 +22202,59 @@ SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (serotonin) + +AnnotationAssertion( "A primary amino compound that is the 5-hydroxy derivative of tryptamine.") +AnnotationAssertion( "0") +AnnotationAssertion( "C10H12N2O") +AnnotationAssertion( "InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2") +AnnotationAssertion( "QZAYGJVTTNCVMB-UHFFFAOYSA-N") +AnnotationAssertion( "176.215") +AnnotationAssertion( "176.09496") +AnnotationAssertion( "C1=CC(=CC=2C(=CNC12)CCN)O") +AnnotationAssertion( "CHEBI:1420") +AnnotationAssertion( "CHEBI:26652") +AnnotationAssertion( "CHEBI:49894") +AnnotationAssertion(Annotation( "Beilstein") "Beilstein:143524") +AnnotationAssertion(Annotation( "ChemIDplus") "CAS:50-67-9") +AnnotationAssertion(Annotation( "KEGG COMPOUND") "CAS:50-67-9") +AnnotationAssertion(Annotation( "Gmelin") "Gmelin:1861995") +AnnotationAssertion( "HMDB:HMDB0000259") +AnnotationAssertion( "KEGG:C00780") +AnnotationAssertion( "KNApSAcK:C00001429") +AnnotationAssertion( "LINCS:LSM-6589") +AnnotationAssertion( "MetaCyc:SEROTONIN") +AnnotationAssertion( "PDBeChem:SRO") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:18593914") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:22770225") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:24136337") +AnnotationAssertion(Annotation( "Reaxys") "Reaxys:143524") +AnnotationAssertion( "Wikipedia:Serotonin") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "3-(2-aminoethyl)-1H-indol-5-ol") +AnnotationAssertion(Annotation( "PDBeChem") "SEROTONIN") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Serotonin") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "3-(2-Aminoethyl)-1H-indol-5-ol") +AnnotationAssertion(Annotation( "IUPHAR") "5-HT") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "5-Hydroxytryptamine") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Enteramine") +AnnotationAssertion(Annotation( "ChEBI") "serotonine") +AnnotationAssertion(Annotation( "ChemIDplus") "thrombocytin") +AnnotationAssertion(Annotation( "ChemIDplus") "thrombotonin") +AnnotationAssertion( "CHEBI:28790") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "serotonin") +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (lutein) AnnotationAssertion( "0") @@ -11949,6 +22300,122 @@ SubClassOf( ObjectSomeValuesFrom( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (fatty acid anion) + +AnnotationAssertion( "The conjugate base of a fatty acid, arising from deprotonation of the carboxylic acid group of the corresponding fatty acid.") +AnnotationAssertion( "-1") +AnnotationAssertion( "CO2R") +AnnotationAssertion( "44.00950") +AnnotationAssertion( "43.98983") +AnnotationAssertion( "[O-]C([*])=O") +AnnotationAssertion( "CHEBI:13634") +AnnotationAssertion( "CHEBI:24022") +AnnotationAssertion( "CHEBI:4985") +AnnotationAssertion( "KEGG:C02403") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:18628202") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Fatty acid anion") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Alkanate") +AnnotationAssertion(Annotation( "ChEBI") "Fettsaeureanion") +AnnotationAssertion(Annotation( "ChEBI") "Fettsaeureanionen") +AnnotationAssertion(Annotation( "UniProt") "a fatty acid") +AnnotationAssertion(Annotation( "ChEBI") "acido graso anionico") +AnnotationAssertion(Annotation( "ChEBI") "acidos grasos anionicos") +AnnotationAssertion(Annotation( "ChEBI") "anion de l'acide gras") +AnnotationAssertion(Annotation( "ChEBI") "fatty acid anions") +AnnotationAssertion( "CHEBI:28868") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "fatty acid anion") +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: ((R)-adrenaline) + +AnnotationAssertion( "The R-enantiomer of adrenaline. It is a hormone secreted by the adrenal glands resulting in the 'fight-or-flight' response.") +AnnotationAssertion( "0") +AnnotationAssertion( "C9H13NO3") +AnnotationAssertion( "InChI=1S/C9H13NO3/c1-10-5-9(13)6-2-3-7(11)8(12)4-6/h2-4,9-13H,5H2,1H3/t9-/m0/s1") +AnnotationAssertion( "UCTWMZQNUQWSLP-VIFPVBQESA-N") +AnnotationAssertion( "183.20440") +AnnotationAssertion( "183.08954") +AnnotationAssertion( "CNC[C@H](O)c1ccc(O)c(O)c1") +AnnotationAssertion( "CHEBI:1942") +AnnotationAssertion( "CHEBI:23928") +AnnotationAssertion(Annotation( "Beilstein") "Beilstein:2368277") +AnnotationAssertion(Annotation( "ChemIDplus") "CAS:51-43-4") +AnnotationAssertion(Annotation( "KEGG COMPOUND") "CAS:51-43-4") +AnnotationAssertion(Annotation( "NIST Chemistry WebBook") "CAS:51-43-4") +AnnotationAssertion( "DrugBank:DB00668") +AnnotationAssertion(Annotation( "DrugCentral") "Drug_Central:1028") +AnnotationAssertion( "HMDB:HMDB0000068") +AnnotationAssertion( "KEGG:C00788") +AnnotationAssertion( "KEGG:D00095") +AnnotationAssertion( "KNApSAcK:C00029643") +AnnotationAssertion( "MetaCyc:L-EPINEPHRINE") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:18325983") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:21963816") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:22115931") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:22405854") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:22425731") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:22429969") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:22569014") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:22623754") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:22826982") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:22895980") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:22898765") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:22905594") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:22940899") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:23066296") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:23130169") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:23164182") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:23185846") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:29438107") +AnnotationAssertion(Annotation( "Reaxys") "Reaxys:2368277") +AnnotationAssertion( "Wikipedia:Epinephrine") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "4-[(1R)-1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChemIDplus") "(-)-(R)-epinephrine") +AnnotationAssertion(Annotation( "NIST_Chemistry_WebBook") "(-)-3,4-dihydroxy-alpha-((methylamino)methyl)benzyl alcohol") +AnnotationAssertion(Annotation( "IUPHAR") "(-)-adrenaline") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "(R)-(-)-Adnephrine") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "(R)-(-)-Adrenaline") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "(R)-(-)-Epinephrine") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "(R)-(-)-Epirenamine") +AnnotationAssertion(Annotation( "ChEBI") "(R)-(-)-adrenaline") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol") +AnnotationAssertion(Annotation( "KEGG_DRUG") Annotation( ) "Adrenalin") +AnnotationAssertion(Annotation( "NIST_Chemistry_WebBook") "Adrenalin") +AnnotationAssertion(Annotation( "ChEBI") "Epinephrin") +AnnotationAssertion(Annotation( "DrugBank") Annotation( ) "Epipen") +AnnotationAssertion(Annotation( "KEGG_DRUG") Annotation( ) "Epipen") +AnnotationAssertion(Annotation( "DrugBank") Annotation( ) "Epipen JR") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "L-Adrenaline") +AnnotationAssertion(Annotation( "DrugBank") Annotation( ) "Primatene") +AnnotationAssertion(Annotation( "ChEBI") "adrenaline") +AnnotationAssertion(Annotation( "NIST_Chemistry_WebBook") "adrenaline") +AnnotationAssertion(Annotation( "ChemIDplus") Annotation( ) "epinefrina") +AnnotationAssertion(Annotation( "ChEBI") Annotation( ) "epinephrine") +AnnotationAssertion(Annotation( "ChemIDplus") Annotation( ) "epinephrine") +AnnotationAssertion(Annotation( "ChemIDplus") Annotation( ) "epinephrinum") +AnnotationAssertion(Annotation( "IUPHAR") "levoepinephrine") +AnnotationAssertion( "CHEBI:28918") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "(R)-adrenaline") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (ammonium) AnnotationAssertion( "An onium cation obtained by protonation of ammonia.") @@ -12122,6 +22589,24 @@ SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (mononucleotide) + +AnnotationAssertion( "0") +AnnotationAssertion( "C5H10O7PR") +AnnotationAssertion( "213.103") +AnnotationAssertion( "213.01641") +AnnotationAssertion( "CHEBI:14616") +AnnotationAssertion( "CHEBI:25404") +AnnotationAssertion( "CHEBI:6983") +AnnotationAssertion( "KEGG:C02171") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Mononucleotide") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "mononucleotides") +AnnotationAssertion( "CHEBI:29075") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "mononucleotide") +SubClassOf( ) + # Class: (sodium(1+)) AnnotationAssertion( "A monoatomic monocation obtained from sodium.") @@ -12238,6 +22723,261 @@ SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (oxonium) + +AnnotationAssertion( "+1") +AnnotationAssertion( "H3O") +AnnotationAssertion( "InChI=1S/H2O/h1H2/p+1") +AnnotationAssertion( "XLYOFNOQVPJJNP-UHFFFAOYSA-O") +AnnotationAssertion( "19.02322") +AnnotationAssertion( "19.01784") +AnnotationAssertion( "[H][O+]([H])[H]") +AnnotationAssertion(Annotation( "ChemIDplus") "CAS:13968-08-6") +AnnotationAssertion(Annotation( "NIST Chemistry WebBook") "CAS:13968-08-6") +AnnotationAssertion(Annotation( "Gmelin") "Gmelin:141") +AnnotationAssertion( "MolBase:1646") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "aquahydrogen(1+)") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "oxidanium") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "oxonium") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "trihydridooxygen(1+)") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "IUPAC") "H3O(+)") +AnnotationAssertion(Annotation( "NIST_Chemistry_WebBook") "Hydronium cation") +AnnotationAssertion(Annotation( "ChemIDplus") "Hydronium ion") +AnnotationAssertion(Annotation( "MolBase") "[OH3](+)") +AnnotationAssertion( "CHEBI:29412") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "oxonium") +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (hydridodioxygen(1+)) + +AnnotationAssertion( "+1") +AnnotationAssertion( "HO2") +AnnotationAssertion( "InChI=1S/O2/c1-2/p+1") +AnnotationAssertion( "MYMOFIZGZYHOMD-UHFFFAOYSA-O") +AnnotationAssertion( "33.00674") +AnnotationAssertion( "32.99711") +AnnotationAssertion( "[H][O+]=O") +AnnotationAssertion(Annotation( "Gmelin") "Gmelin:508") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "dioxidenium") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "hydridodioxygen(1+)") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "IUPAC") "HO2(+)") +AnnotationAssertion(Annotation( "ChEBI") "HOO(+)") +AnnotationAssertion(Annotation( "ChEBI") "[HO2](+)") +AnnotationAssertion( "CHEBI:29793") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "hydridodioxygen(1+)") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (L-glutamate(1-)) + +AnnotationAssertion( "An alpha-amino-acid anion that is the conjugate base of L-glutamic acid, having anionic carboxy groups and a cationic amino group") +AnnotationAssertion( "-1") +AnnotationAssertion( "C5H8NO4") +AnnotationAssertion( "InChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/p-1/t3-/m0/s1") +AnnotationAssertion( "WHUUTDBJXJRKMK-VKHMYHEASA-M") +AnnotationAssertion( "146.12136") +AnnotationAssertion( "146.04588") +AnnotationAssertion( "[NH3+][C@@H](CCC([O-])=O)C([O-])=O") +AnnotationAssertion( "CHEBI:13107") +AnnotationAssertion( "CHEBI:21301") +AnnotationAssertion(Annotation( "ChemIDplus") "CAS:11070-68-1") +AnnotationAssertion(Annotation( "Gmelin") "Gmelin:936654") +AnnotationAssertion( "MetaCyc:GLT") +AnnotationAssertion(Annotation( "JCBN") "L-glutamate(1-)") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "hydrogen L-glutamate") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "IUPAC") "(2S)-2-ammoniopentanedioate") +AnnotationAssertion(Annotation( "ChEBI") "L-glutamate") +AnnotationAssertion(Annotation( "UniProt") "L-glutamate") +AnnotationAssertion(Annotation( "JCBN") "L-glutamic acid monoanion") +AnnotationAssertion(Annotation( "ChemIDplus") "L-glutamic acid, ion(1-)") +AnnotationAssertion( "CHEBI:29985") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "L-glutamate(1-)") +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (D-glutamate(1-)) + +AnnotationAssertion( "An alpha-amino-acid anion that is the conjugate base of D-glutamic acid, having anionic carboxy groups and a cationic amino group") +AnnotationAssertion( "-1") +AnnotationAssertion( "C5H8NO4") +AnnotationAssertion( "InChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/p-1/t3-/m1/s1") +AnnotationAssertion( "WHUUTDBJXJRKMK-GSVOUGTGSA-M") +AnnotationAssertion( "146.12136") +AnnotationAssertion( "146.04588") +AnnotationAssertion( "[NH3+][C@H](CCC([O-])=O)C([O-])=O") +AnnotationAssertion( "CHEBI:12979") +AnnotationAssertion( "CHEBI:21022") +AnnotationAssertion(Annotation( "Beilstein") "Beilstein:8319427") +AnnotationAssertion( "MetaCyc:D-GLT") +AnnotationAssertion(Annotation( "JCBN") "D-glutamate(1-)") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "hydrogen D-glutamate") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "IUPAC") "(2R)-2-ammoniopentanedioate") +AnnotationAssertion(Annotation( "UniProt") "D-glutamate") +AnnotationAssertion(Annotation( "JCBN") "D-glutamic acid monoanion") +AnnotationAssertion( "CHEBI:29986") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "D-glutamate(1-)") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (glutamate(2-)) + +AnnotationAssertion( "A dicarboxylic acid dianion that is the conjugate base of glutamate(1-).") +AnnotationAssertion( "-2") +AnnotationAssertion( "C5H7NO4") +AnnotationAssertion( "InChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/p-2") +AnnotationAssertion( "WHUUTDBJXJRKMK-UHFFFAOYSA-L") +AnnotationAssertion( "145.11342") +AnnotationAssertion( "145.03860") +AnnotationAssertion( "NC(CCC([O-])=O)C([O-])=O") +AnnotationAssertion(Annotation( "Beilstein") "Beilstein:4134100") +AnnotationAssertion(Annotation( "Gmelin") "Gmelin:327903") +AnnotationAssertion(Annotation( "Reaxys") "Reaxys:4134100") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "2-aminopentanedioate") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "glutamate") +AnnotationAssertion(Annotation( "JCBN") "glutamate(2-)") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "JCBN") "glutamic acid dianion") +AnnotationAssertion( "CHEBI:29987") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "glutamate(2-)") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (L-glutamate(2-)) + +AnnotationAssertion( "An L-alpha-amino acid anion that is the dianion obtained by the deprotonation of the both the carboxy groups of L-glutamic acid.") +AnnotationAssertion( "-2") +AnnotationAssertion( "C5H7NO4") +AnnotationAssertion( "InChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/p-2/t3-/m0/s1") +AnnotationAssertion( "WHUUTDBJXJRKMK-VKHMYHEASA-L") +AnnotationAssertion( "145.11342") +AnnotationAssertion( "145.03860") +AnnotationAssertion( "N[C@@H](CCC([O-])=O)C([O-])=O") +AnnotationAssertion(Annotation( "Gmelin") "Gmelin:327905") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "(2S)-2-aminopentanedioate") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "L-glutamate") +AnnotationAssertion(Annotation( "JCBN") "L-glutamate(2-)") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "JCBN") "L-glutamic acid dianion") +AnnotationAssertion( "CHEBI:29988") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "L-glutamate(2-)") +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (D-glutamate(2-)) + +AnnotationAssertion( "-2") +AnnotationAssertion( "C5H7NO4") +AnnotationAssertion( "InChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/p-2/t3-/m1/s1") +AnnotationAssertion( "WHUUTDBJXJRKMK-GSVOUGTGSA-L") +AnnotationAssertion( "145.11342") +AnnotationAssertion( "145.03860") +AnnotationAssertion( "N[C@H](CCC([O-])=O)C([O-])=O") +AnnotationAssertion(Annotation( "Beilstein") "Beilstein:8143000") +AnnotationAssertion(Annotation( "Gmelin") "Gmelin:327904") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "(2R)-2-aminopentanedioate") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "D-glutamate") +AnnotationAssertion(Annotation( "JCBN") "D-glutamate(2-)") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "JCBN") "D-glutamic acid dianion") +AnnotationAssertion( "CHEBI:29989") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "D-glutamate(2-)") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (acetate) + +AnnotationAssertion( "A monocarboxylic acid anion resulting from the removal of a proton from the carboxy group of acetic acid.") +AnnotationAssertion( "-1") +AnnotationAssertion( "C2H3O2") +AnnotationAssertion( "InChI=1S/C2H4O2/c1-2(3)4/h1H3,(H,3,4)/p-1") +AnnotationAssertion( "QTBSBXVTEAMEQO-UHFFFAOYSA-M") +AnnotationAssertion( "59.04402") +AnnotationAssertion( "59.01385") +AnnotationAssertion( "CC([O-])=O") +AnnotationAssertion( "CHEBI:13704") +AnnotationAssertion( "CHEBI:22165") +AnnotationAssertion( "CHEBI:40480") +AnnotationAssertion(Annotation( "Beilstein") "Beilstein:1901470") +AnnotationAssertion(Annotation( "ChemIDplus") "CAS:71-50-1") +AnnotationAssertion(Annotation( "NIST Chemistry WebBook") "CAS:71-50-1") +AnnotationAssertion( "DrugBank:DB03166") +AnnotationAssertion(Annotation( "Gmelin") "Gmelin:1379") +AnnotationAssertion( "KEGG:C00033") +AnnotationAssertion( "MetaCyc:ACET") +AnnotationAssertion( "PDBeChem:ACT") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:17190852") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:22211106") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:22371380") +AnnotationAssertion(Annotation( "Reaxys") "Reaxys:1901470") +AnnotationAssertion(Annotation( "UM-BBD") "UM-BBD_compID:c0050") +AnnotationAssertion( "Wikipedia:Acetate") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "acetate") +AnnotationAssertion(Annotation( "UniProt") "acetate") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "PDBeChem") "ACETATE ION") +AnnotationAssertion(Annotation( "ChEBI") "Azetat") +AnnotationAssertion(Annotation( "IUPAC") "CH3-COO(-)") +AnnotationAssertion(Annotation( "ChEBI") "Ethanoat") +AnnotationAssertion(Annotation( "NIST_Chemistry_WebBook") "MeCO2 anion") +AnnotationAssertion(Annotation( "ChemIDplus") "acetic acid, ion(1-)") +AnnotationAssertion(Annotation( "ChEBI") "ethanoate") +AnnotationAssertion( "CHEBI:30089") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "acetate") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (photon) + +AnnotationAssertion( "Particle of zero charge, zero rest mass, spin quantum number 1, energy hnu and momentum hnu/c (h is the Planck constant, nu the frequency of radiation and c the speed of light), carrier of electromagnetic force.") +AnnotationAssertion( "0") +AnnotationAssertion( "0.0") +AnnotationAssertion( "0.0") +AnnotationAssertion( "*") +AnnotationAssertion( "CHEBI:10581") +AnnotationAssertion( "CHEBI:14383") +AnnotationAssertion( "KEGG:C00205") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "photon") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "Lichtquant") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Light") +AnnotationAssertion(Annotation( "ChEBI") "foton") +AnnotationAssertion(Annotation( "IUPAC") "gamma") +AnnotationAssertion(Annotation( "IUPAC") "hnu") +AnnotationAssertion(Annotation( "UniProt") "hnu") +AnnotationAssertion(Annotation( "ChEBI") "light quantum") +AnnotationAssertion( "CHEBI:30212") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "photon") +SubClassOf( ) + # Class: (monoatomic dication) AnnotationAssertion( "+2") @@ -12255,6 +22995,280 @@ AnnotationAssertion( "monoatomic dication") SubClassOf( ) +# Class: (gamma-aminobutyrate) + +AnnotationAssertion( "An gamma-amino acid anion resulting from the deprotonation of the carboxy group of gamma-aminobutyric acid.") +AnnotationAssertion( "-1") +AnnotationAssertion( "C4H8NO2") +AnnotationAssertion( "InChI=1S/C4H9NO2/c5-3-1-2-4(6)7/h1-3,5H2,(H,6,7)/p-1") +AnnotationAssertion( "BTCSSZJGUNDROE-UHFFFAOYSA-M") +AnnotationAssertion( "102.11186") +AnnotationAssertion( "102.05605") +AnnotationAssertion( "NCCCC([O-])=O") +AnnotationAssertion( "CHEBI:11961") +AnnotationAssertion( "CHEBI:20317") +AnnotationAssertion(Annotation( "Beilstein") "Beilstein:3536873") +AnnotationAssertion(Annotation( "Gmelin") "Gmelin:559138") +AnnotationAssertion( "KEGG:C00334") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:12509893") +AnnotationAssertion(Annotation( "Reaxys") "Reaxys:3536873") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "4-aminobutanoate") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "4-Amino-butyrat") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "4-Aminobutylate") +AnnotationAssertion(Annotation( "ChEBI") "4-aminobutanoic acid ion (1-)") +AnnotationAssertion(Annotation( "ChEBI") "4-aminobutyrate") +AnnotationAssertion(Annotation( "ChEBI") "gamma-aminobutanoate") +AnnotationAssertion(Annotation( "ChEBI") "gamma-aminobutyrate anion") +AnnotationAssertion( "CHEBI:30566") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "gamma-aminobutyrate") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (ATP(4-)) + +AnnotationAssertion( "A nucleoside triphosphate(4-) obtained by global deprotonation of the triphosphate OH groups of ATP; major species present at pH 7.3.") +AnnotationAssertion( "-4") +AnnotationAssertion( "C10H12N5O13P3") +AnnotationAssertion( "InChI=1S/C10H16N5O13P3/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20)/p-4/t4-,6-,7-,10-/m1/s1") +AnnotationAssertion( "ZKHQWZAMYRWXGA-KQYNXXCUSA-J") +AnnotationAssertion( "503.14946") +AnnotationAssertion( "502.96664") +AnnotationAssertion( "Nc1ncnc2n(cnc12)[C@@H]1O[C@H](COP([O-])(=O)OP([O-])(=O)OP([O-])([O-])=O)[C@@H](O)[C@H]1O") +AnnotationAssertion(Annotation( "Beilstein") "Beilstein:3581767") +AnnotationAssertion(Annotation( "Gmelin") "Gmelin:342798") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "adenosine 5'-triphosphate(4-)") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "UniProt") "ATP") +AnnotationAssertion(Annotation( "IUPAC") "atp") +AnnotationAssertion( "CHEBI:30616") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "ATP(4-)") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (formic acid) + +AnnotationAssertion( "The simplest carboxylic acid, containing a single carbon. Occurs naturally in various sources including the venom of bee and ant stings, and is a useful organic synthetic reagent. Principally used as a preservative and antibacterial agent in livestock feed. Induces severe metabolic acidosis and ocular injury in human subjects.") +AnnotationAssertion( "0") +AnnotationAssertion( "CH2O2") +AnnotationAssertion( "InChI=1S/CH2O2/c2-1-3/h1H,(H,2,3)") +AnnotationAssertion( "BDAGIHXWWSANSR-UHFFFAOYSA-N") +AnnotationAssertion( "46.02538") +AnnotationAssertion( "46.00548") +AnnotationAssertion( "[H]C(O)=O") +AnnotationAssertion( "CHEBI:24082") +AnnotationAssertion( "CHEBI:42460") +AnnotationAssertion( "CHEBI:5145") +AnnotationAssertion( "BPDB:1749") +AnnotationAssertion(Annotation( "Beilstein") "Beilstein:1209246") +AnnotationAssertion(Annotation( "ChemIDplus") "CAS:64-18-6") +AnnotationAssertion(Annotation( "KEGG COMPOUND") "CAS:64-18-6") +AnnotationAssertion(Annotation( "NIST Chemistry WebBook") "CAS:64-18-6") +AnnotationAssertion( "DrugBank:DB01942") +AnnotationAssertion(Annotation( "Gmelin") "Gmelin:1008") +AnnotationAssertion( "HMDB:HMDB0000142") +AnnotationAssertion( "KEGG:C00058") +AnnotationAssertion( "KNApSAcK:C00001182") +AnnotationAssertion(Annotation( "LIPID MAPS") "LIPID_MAPS_instance:LMFA01010040") +AnnotationAssertion( "MetaCyc:FORMATE") +AnnotationAssertion( "PDBeChem:FMT") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:12591956") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:14637377") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:15811469") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:16120414") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:16185830") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:16222862") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:16230297") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:16445901") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:16465784") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:18034701") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:18397576") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:22080171") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:22280475") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:22304812") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:22385261") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:22447125") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:22483350") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:22499553") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:22540994") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:22606986") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:22622393") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:3946945") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:7361809") +AnnotationAssertion( "Patent:CN101481304") +AnnotationAssertion(Annotation( "Reaxys") "Reaxys:1209246") +AnnotationAssertion( "Wikipedia:Formic_acid") +AnnotationAssertion(Annotation( "PDBeChem") "FORMIC ACID") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Formic acid") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "formic acid") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChemIDplus") "Acide formique") +AnnotationAssertion(Annotation( "ChemIDplus") "Ameisensaeure") +AnnotationAssertion(Annotation( "IUPAC") "H-COOH") +AnnotationAssertion(Annotation( "ChEBI") "HCO2H") +AnnotationAssertion(Annotation( "NIST_Chemistry_WebBook") "HCOOH") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Methanoic acid") +AnnotationAssertion(Annotation( "ChemIDplus") "aminic acid") +AnnotationAssertion(Annotation( "ChemIDplus") "bilorin") +AnnotationAssertion(Annotation( "ChemIDplus") "formylic acid") +AnnotationAssertion(Annotation( "ChemIDplus") "hydrogen carboxylic acid") +AnnotationAssertion(Annotation( "ChEBI") "methoic acid") +AnnotationAssertion( "CHEBI:30751") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "formic acid") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (butyric acid) + +AnnotationAssertion( "A straight-chain saturated fatty acid that is butane in which one of the terminal methyl groups has been oxidised to a carboxy group.") +AnnotationAssertion( "0") +AnnotationAssertion( "C4H8O2") +AnnotationAssertion( "InChI=1S/C4H8O2/c1-2-3-4(5)6/h2-3H2,1H3,(H,5,6)") +AnnotationAssertion( "FERIUCNNQQJTOY-UHFFFAOYSA-N") +AnnotationAssertion( "88.10510") +AnnotationAssertion( "88.05243") +AnnotationAssertion( "CCCC(O)=O") +AnnotationAssertion( "CHEBI:113450") +AnnotationAssertion( "CHEBI:22948") +AnnotationAssertion( "CHEBI:3234") +AnnotationAssertion( "CHEBI:41208") +AnnotationAssertion(Annotation( "Beilstein") "Beilstein:906770") +AnnotationAssertion(Annotation( "ChemIDplus") "CAS:107-92-6") +AnnotationAssertion(Annotation( "KEGG COMPOUND") "CAS:107-92-6") +AnnotationAssertion(Annotation( "NIST Chemistry WebBook") "CAS:107-92-6") +AnnotationAssertion( "DrugBank:DB03568") +AnnotationAssertion(Annotation( "Gmelin") "Gmelin:26242") +AnnotationAssertion( "HMDB:HMDB0000039") +AnnotationAssertion( "KEGG:C00246") +AnnotationAssertion( "KNApSAcK:C00001180") +AnnotationAssertion(Annotation( "LIPID MAPS") "LIPID_MAPS_instance:LMFA01010004") +AnnotationAssertion( "MetaCyc:BUTYRIC_ACID") +AnnotationAssertion( "PDBeChem:BUA") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:10736622") +AnnotationAssertion(Annotation( "ChEMBL") "PMID:10956204") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:11201044") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:11208715") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:11238216") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:11305323") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:12068484") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:13678314") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:14962641") +AnnotationAssertion(Annotation( "ChEMBL") "PMID:1542095") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:15809727") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:15810631") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:15938880") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:19318247") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:19366864") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:19703412") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:21699495") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:22038864") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:22194341") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:22322557") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:22339023") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:22466881") +AnnotationAssertion(Annotation( "Reaxys") "Reaxys:906770") +AnnotationAssertion( "Wikipedia:Butyric_acid") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Butyric acid") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "butanoic acid") +AnnotationAssertion(Annotation( "IUPAC") "butyric acid") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "HMDB") "1-butanoic acid") +AnnotationAssertion(Annotation( "HMDB") "1-butyric acid") +AnnotationAssertion(Annotation( "MetaCyc") "1-propanecarboxylic acid") +AnnotationAssertion(Annotation( "ChEBI") "4:0") +AnnotationAssertion(Annotation( "PDBeChem") "BUTANOIC ACID") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Butanoate") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Butanoic acid") +AnnotationAssertion(Annotation( "ChEBI") "Buttersaeure") +AnnotationAssertion(Annotation( "ChEBI") "C4:0") +AnnotationAssertion(Annotation( "IUPAC") "CH3-[CH2]2-COOH") +AnnotationAssertion(Annotation( "IUPAC") "acide butanoique") +AnnotationAssertion(Annotation( "ChEBI") "acide butyrique") +AnnotationAssertion(Annotation( "ChEBI") "butanic acid") +AnnotationAssertion(Annotation( "ChEBI") "butoic acid") +AnnotationAssertion(Annotation( "NIST_Chemistry_WebBook") "ethylacetic acid") +AnnotationAssertion(Annotation( "NIST_Chemistry_WebBook") "n-butanoic acid") +AnnotationAssertion(Annotation( "NIST_Chemistry_WebBook") "n-butyric acid") +AnnotationAssertion(Annotation( "HMDB") "propanecarboxylic acid") +AnnotationAssertion(Annotation( "MetaCyc") "propylformic acid") +AnnotationAssertion( "CHEBI:30772") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "butyric acid") +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (alcohol) + +AnnotationAssertion( "A compound in which a hydroxy group, -OH, is attached to a saturated carbon atom.") +AnnotationAssertion( "0") +AnnotationAssertion( "HOR") +AnnotationAssertion( "17.007") +AnnotationAssertion( "17.00274") +AnnotationAssertion( "O[*]") +AnnotationAssertion( "CHEBI:13804") +AnnotationAssertion( "CHEBI:22288") +AnnotationAssertion( "CHEBI:2553") +AnnotationAssertion( "KEGG:C00069") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Alcohol") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "alcohols") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "UniProt") "an alcohol") +AnnotationAssertion( "CHEBI:30879") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "alcohol") +SubClassOf( ) + +# Class: (bile acid) + +AnnotationAssertion( "Any member of a group of hydroxy-5beta-cholanic acids occuring in bile, where they are present as the sodium salts of their amides with glycine or taurine. In mammals bile acids almost invariably have 5beta-configuration.") +AnnotationAssertion( "KEGG:C01558") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Bile acid") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "5beta-bile acid") +AnnotationAssertion(Annotation( "ChEBI") "5beta-bile acids") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Bile salt") +AnnotationAssertion(Annotation( "ChEBI") "Gallensaeure") +AnnotationAssertion(Annotation( "ChEBI") "Gallensaeuren") +AnnotationAssertion(Annotation( "ChEBI") "bile acids") +AnnotationAssertion( "CHEBI:3098") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "bile acid") +SubClassOf( ) +SubClassOf( ) + +# Class: (amine) + +AnnotationAssertion( "A compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups.") +AnnotationAssertion( "CHEBI:13814") +AnnotationAssertion( "CHEBI:22474") +AnnotationAssertion( "CHEBI:2641") +AnnotationAssertion( "KEGG:C00706") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Amine") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "amines") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "Amin") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Substituted amine") +AnnotationAssertion( "CHEBI:32952") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "amine") +SubClassOf( ) + # Class: (amide) AnnotationAssertion( "An amide is a derivative of an oxoacid RkE(=O)l(OH)m (l =/= 0) in which an acidic hydroxy group has been replaced by an amino or substituted amino group.") @@ -12473,6 +23487,23 @@ SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (monoatomic hydrogen) + +AnnotationAssertion( "0") +AnnotationAssertion( "H") +AnnotationAssertion( "InChI=1S/H") +AnnotationAssertion( "YZCKVEUIGOORGS-UHFFFAOYSA-N") +AnnotationAssertion( "1.00794") +AnnotationAssertion( "1.00783") +AnnotationAssertion( "[H]") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "atomic hydrogen") +AnnotationAssertion( "CHEBI:33251") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "monoatomic hydrogen") +SubClassOf( ) +SubClassOf( ) + # Class: (atomic nucleus) AnnotationAssertion( "A nucleus is the positively charged central portion of an atom, excluding the orbital electrons.") @@ -12530,6 +23561,38 @@ AnnotationAssertion( "elemental molecular entity") SubClassOf( ) +# Class: (elemental hydrogen) + +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion( "CHEBI:33260") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "elemental hydrogen") +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (elemental oxygen) + +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion( "CHEBI:33262") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "elemental oxygen") +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (diatomic oxygen) + +AnnotationAssertion( "0") +AnnotationAssertion( "O2") +AnnotationAssertion( "31.999") +AnnotationAssertion( "31.98983") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion( "CHEBI:33263") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "diatomic oxygen") +SubClassOf( ) + # Class: (polyatomic anion) AnnotationAssertion( "An anion consisting of more than one atom.") @@ -12550,6 +23613,45 @@ AnnotationAssertion( "molecular messenger") SubClassOf( ) +# Class: (antimicrobial agent) + +AnnotationAssertion( "A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans.") +AnnotationAssertion( "CHEBI:22582") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:12964249") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:22117953") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:22439833") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:22849268") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:22849276") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:22958833") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "Antibiotika") +AnnotationAssertion(Annotation( "ChEBI") "Antibiotikum") +AnnotationAssertion(Annotation( "ChEBI") "antibiotic") +AnnotationAssertion(Annotation( "ChEBI") "antibiotics") +AnnotationAssertion(Annotation( "IUPAC") "antibiotique") +AnnotationAssertion(Annotation( "ChEBI") "antimicrobial") +AnnotationAssertion(Annotation( "ChEBI") "antimicrobial agents") +AnnotationAssertion(Annotation( "ChEBI") "antimicrobials") +AnnotationAssertion(Annotation( "ChEBI") "microbicide") +AnnotationAssertion(Annotation( "ChEBI") "microbicides") +AnnotationAssertion( "CHEBI:33281") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "antimicrobial agent") +SubClassOf( ) + +# Class: (antibacterial agent) + +AnnotationAssertion( "A substance (or active part thereof) that kills or slows the growth of bacteria.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "antibacterial agents") +AnnotationAssertion(Annotation( "ChEBI") "antibacterials") +AnnotationAssertion(Annotation( "ChEBI") "bactericide") +AnnotationAssertion(Annotation( "ChEBI") "bactericides") +AnnotationAssertion( "CHEBI:33282") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "antibacterial agent") +SubClassOf( ) + # Class: (nutrient) AnnotationAssertion( "A nutrient is a food component that an organism uses to survive and grow.") @@ -12596,6 +23698,32 @@ AnnotationAssertion( "fertilizer") SubClassOf( ) +# Class: (food) + +AnnotationAssertion( "A physiological role played by any substance of either plant, animal or artificial origin which contains essential body nutrients that can be ingested by an organism to provide energy, promote growth, and maintain the processes of life.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "food material") +AnnotationAssertion(Annotation( "ChEBI") "food materials") +AnnotationAssertion(Annotation( "ChEBI") "food role") +AnnotationAssertion(Annotation( "ChEBI") "foods") +AnnotationAssertion(Annotation( "ChEBI") "foodstuff") +AnnotationAssertion(Annotation( "ChEBI") "foodstuffs") +AnnotationAssertion( "CHEBI:33290") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "food") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (diagnostic agent) + +AnnotationAssertion( "A substance administered to aid diagnosis of a disease.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "diagnostic aid") +AnnotationAssertion( "CHEBI:33295") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "diagnostic agent") +SubClassOf( ) + # Class: (alkali metal molecular entity) AnnotationAssertion( "A molecular entity containing one or more atoms of an alkali metal.") @@ -12699,6 +23827,30 @@ AnnotationAssertion( "carbon group element atom") SubClassOf( ) +# Class: (carboxylic ester) + +AnnotationAssertion( "An ester of a carboxylic acid, R(1)C(=O)OR(2), where R(1) = H or organyl and R(2) = organyl.") +AnnotationAssertion( "0") +AnnotationAssertion( "CO2R2") +AnnotationAssertion( "44.010") +AnnotationAssertion( "43.98983") +AnnotationAssertion( "[*]C(=O)O[*]") +AnnotationAssertion( "CHEBI:13204") +AnnotationAssertion( "CHEBI:23028") +AnnotationAssertion( "CHEBI:3408") +AnnotationAssertion( "KEGG:C02391") +AnnotationAssertion( "Wikipedia:Ester") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Carboxylic ester") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "carboxylic esters") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "UniProt") "a carboxylic ester") +AnnotationAssertion(Annotation( "ChEBI") "carboxylic acid esters") +AnnotationAssertion( "CHEBI:33308") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "carboxylic ester") +SubClassOf( ) +SubClassOf( ) + # Class: (main group element atom) AnnotationAssertion( "An atom belonging to one of the main groups (found in the s- and p- blocks) of the periodic table.") @@ -12712,6 +23864,18 @@ AnnotationAssertion( "main group element atom") SubClassOf( ) +# Class: (iron group element atom) + +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "group 8 elements") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "iron group element") +AnnotationAssertion(Annotation( "ChEBI") "iron group elements") +AnnotationAssertion( "CHEBI:33356") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "iron group element atom") +SubClassOf( ) +SubClassOf( ) + # Class: (sulfur oxoacid) AnnotationAssertion( "chebi_ontology") @@ -12745,6 +23909,29 @@ AnnotationAssertion(rdfs:label "sul SubClassOf( ) SubClassOf( ) +# Class: (phospho sugar) + +AnnotationAssertion( "Any monosaccharide containing an alcoholic hydroxy group esterified with phosphoric acid.") +AnnotationAssertion( "CHEBI:15132") +AnnotationAssertion( "CHEBI:25406") +AnnotationAssertion( "CHEBI:26086") +AnnotationAssertion( "CHEBI:9320") +AnnotationAssertion( "KEGG:C00934") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:18186488") +AnnotationAssertion(Annotation( "ChEBI") "phospho sugar") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "monosaccharide phosphates") +AnnotationAssertion(Annotation( "ChEBI") "phospho sugars") +AnnotationAssertion(Annotation( "ChEBI") "phosphorylated sugar") +AnnotationAssertion(Annotation( "ChEBI") "phosphorylated sugars") +AnnotationAssertion(Annotation( "ChEBI") "phosphosugar") +AnnotationAssertion(Annotation( "ChEBI") "phosphosugars") +AnnotationAssertion( "CHEBI:33447") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "phospho sugar") +SubClassOf( ) +SubClassOf( ) + # Class: (phosphorus oxoacid) AnnotationAssertion( "A pnictogen oxoacid which contains phosphorus and oxygen, at least one hydrogen atom bound to oxygen, and forms an ion by the loss of one or more protons.") @@ -12818,6 +24005,18 @@ AnnotationAssertion(rdfs:label "cha SubClassOf( ) SubClassOf( ) +# Class: (transition element molecular entity) + +AnnotationAssertion( "A molecular entity containing one or more atoms of a transition element.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "transition element molecular entities") +AnnotationAssertion(Annotation( "ChEBI") "transition metal molecular entity") +AnnotationAssertion( "CHEBI:33497") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "transition element molecular entity") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (alkali metal cation) AnnotationAssertion( "chebi_ontology") @@ -12839,6 +24038,16 @@ AnnotationAssertion(rdfs:label "alk SubClassOf( ) SubClassOf( ) +# Class: (transition element cation) + +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "transition element cations") +AnnotationAssertion(Annotation( "ChEBI") "transition metal cation") +AnnotationAssertion( "CHEBI:33515") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "transition element cation") +SubClassOf( ) + # Class: (metal atom) AnnotationAssertion( "An atom of an element that exhibits typical metallic properties, being typically shiny, with high electrical and thermal conductivity.") @@ -12892,6 +24101,17 @@ AnnotationAssertion( "p-block element atom") SubClassOf( ) +# Class: (d-block element atom) + +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "d-block element") +AnnotationAssertion(Annotation( "ChEBI") "d-block elements") +AnnotationAssertion( "CHEBI:33561") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "d-block element atom") +SubClassOf( ) +SubClassOf( ) + # Class: (glycolipid) AnnotationAssertion( "Any member of class of 1,2-di-O-acylglycerols joined at oxygen 3 by a glycosidic linkage to a carbohydrate part (usually a mono-, di- or tri-saccharide). Some substances classified as bacterial glycolipids have the sugar part acylated by one or more fatty acids and the glycerol part may be absent.") @@ -12907,6 +24127,141 @@ AnnotationAssertion( "glycolipid") SubClassOf( ) +# Class: (catechols) + +AnnotationAssertion( "Any compound containing an o-diphenol component.") +AnnotationAssertion( "0") +AnnotationAssertion( "C6H2O2R4") +AnnotationAssertion( "106.079") +AnnotationAssertion( "106.00548") +AnnotationAssertion( "OC1=C(O)C(*)=C(*)C(*)=C1*") +AnnotationAssertion( "CHEBI:134187") +AnnotationAssertion( "CHEBI:13628") +AnnotationAssertion( "CHEBI:18862") +AnnotationAssertion( "KEGG:C15571") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "1,2-benzenediols") +AnnotationAssertion(Annotation( "UniProt") "a catechol") +AnnotationAssertion(Annotation( "ChEBI") "benzene-1,2-diols") +AnnotationAssertion( "CHEBI:33566") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "catechols") +SubClassOf( ) + +# Class: (catecholamine) + +AnnotationAssertion( "4-(2-Aminoethyl)pyrocatechol [4-(2-aminoethyl)benzene-1,2-diol] and derivatives formed by substitution.") +AnnotationAssertion( "0") +AnnotationAssertion( "C8H9NO2R2") +AnnotationAssertion( "151.163") +AnnotationAssertion( "151.06333") +AnnotationAssertion( "CHEBI:23056") +AnnotationAssertion( "CHEBI:3468") +AnnotationAssertion( "KEGG:C02012") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Catecholamine") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "catecholamines") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "catecholamines") +AnnotationAssertion( "CHEBI:33567") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "catecholamine") +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (adrenaline) + +AnnotationAssertion( "A racemate comprising equimolar amounts of (R)-adrenaline and (S)-adrenaline.") +AnnotationAssertion( "0") +AnnotationAssertion( "C9H13NO3") +AnnotationAssertion( "183.207") +AnnotationAssertion( "183.08954") +AnnotationAssertion(Annotation( "ChemIDplus") "Beilstein:2212160") +AnnotationAssertion(Annotation( "ChemIDplus") "CAS:329-65-7") +AnnotationAssertion(Annotation( "DrugCentral") "Drug_Central:4508") +AnnotationAssertion(Annotation( "Gmelin") "Gmelin:51559") +AnnotationAssertion( "LINCS:LSM-4958") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:10052027") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:24252294") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:24719616") +AnnotationAssertion(Annotation( "Reaxys") "Reaxys:2212160") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "rac-4-[1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "IUPHAR") "(+-)-adrenaline") +AnnotationAssertion(Annotation( "ChemIDplus") "(+-)-epinephrine") +AnnotationAssertion(Annotation( "ChemIDplus") "2-(methylamino)-1-(3,4-dihydroxyphenyl)ethanol") +AnnotationAssertion(Annotation( "ChemIDplus") "dl-adrenaline") +AnnotationAssertion(Annotation( "ChemIDplus") "epinephrine racemic") +AnnotationAssertion(Annotation( "ChEBI") "rac-adrenaline") +AnnotationAssertion(Annotation( "ChEBI") "racemic adrenaline") +AnnotationAssertion(Annotation( "ChemIDplus") Annotation( ) "racepinefrina") +AnnotationAssertion(Annotation( "ChemIDplus") Annotation( ) "racepinefrine") +AnnotationAssertion(Annotation( "ChemIDplus") Annotation( ) "racepinefrinum") +AnnotationAssertion( "CHEBI:33568") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "adrenaline") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (noradrenaline) + +AnnotationAssertion( "A catecholamine in which C-1 of the aminoethyl side-chain is hydroxy-substituted.") +AnnotationAssertion( "0") +AnnotationAssertion( "C8H11NO3") +AnnotationAssertion( "InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2") +AnnotationAssertion( "SFLSHLFXELFNJZ-UHFFFAOYSA-N") +AnnotationAssertion( "169.17788") +AnnotationAssertion( "169.07389") +AnnotationAssertion( "NCC(O)c1ccc(O)c(O)c1") +AnnotationAssertion(Annotation( "Beilstein") "Beilstein:2210994") +AnnotationAssertion(Annotation( "ChemIDplus") "CAS:138-65-8") +AnnotationAssertion(Annotation( "NIST Chemistry WebBook") "CAS:138-65-8") +AnnotationAssertion(Annotation( "Gmelin") "Gmelin:863925") +AnnotationAssertion( "LINCS:LSM-5181") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "4-(2-amino-1-hydroxyethyl)benzene-1,2-diol") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "noradrenalina") +AnnotationAssertion(Annotation( "ChEBI") "norepinephrine") +AnnotationAssertion( "CHEBI:33569") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "noradrenaline") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (benzenediols) + +AnnotationAssertion( "CHEBI:22705") +AnnotationAssertion( "CHEBI:22711") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion( "CHEBI:33570") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "benzenediols") +SubClassOf( ) + +# Class: ((S)-noradrenaline) + +AnnotationAssertion( "The S-enantiomer of noradrenaline.") +AnnotationAssertion( "0") +AnnotationAssertion( "C8H11NO3") +AnnotationAssertion( "InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2/t8-/m1/s1") +AnnotationAssertion( "SFLSHLFXELFNJZ-MRVPVSSYSA-N") +AnnotationAssertion( "169.17788") +AnnotationAssertion( "169.07389") +AnnotationAssertion( "NC[C@@H](O)c1ccc(O)c(O)c1") +AnnotationAssertion(Annotation( "Beilstein") "Beilstein:2937999") +AnnotationAssertion( "LINCS:LSM-37072") +AnnotationAssertion(Annotation( "Reaxys") "Reaxys:2937999") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "4-[(1S)-2-amino-1-hydroxyethyl]benzene-1,2-diol") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion( "CHEBI:33571") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "(S)-noradrenaline") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (carboxylic acid) AnnotationAssertion( "A carbon oxoacid acid carrying at least one -C(=O)OH group and having the structure RC(=O)OH, where R is any any monovalent functional group. Carboxylic acids are the most common type of organic acid.") @@ -12995,6 +24350,16 @@ AnnotationAssertion( "polycyclic compound") SubClassOf( ) +# Class: (bicyclic compound) + +AnnotationAssertion( "A molecule that features two fused rings.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "bicyclic compounds") +AnnotationAssertion( "CHEBI:33636") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "bicyclic compound") +SubClassOf( ) + # Class: (aliphatic compound) AnnotationAssertion( "Any acyclic or cyclic, saturated or unsaturated carbon compound, excluding aromatic compounds.") @@ -13028,6 +24393,49 @@ AnnotationAssertion(rdfs:label "org SubClassOf( ) SubClassOf( ) +# Class: (monocyclic compound) + +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "monocyclic compounds") +AnnotationAssertion( "CHEBI:33661") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "monocyclic compound") +SubClassOf( ) + +# Class: (heteromonocyclic compound) + +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "heteromonocyclic compound") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "heteromonocyclic compounds") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion( "CHEBI:33670") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "heteromonocyclic compound") +SubClassOf( ) +SubClassOf( ) + +# Class: (heteropolycyclic compound) + +AnnotationAssertion( "A polycyclic compound in which at least one of the rings contains at least one non-carbon atom.") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "heteropolycyclic compounds") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "polyheterocyclic compounds") +AnnotationAssertion( "CHEBI:33671") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "heteropolycyclic compound") +SubClassOf( ) +SubClassOf( ) + +# Class: (heterobicyclic compound) + +AnnotationAssertion( "A bicyclic compound in which at least one of the rings contains at least one skeletal heteroatom.") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "heterobicyclic compounds") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion( "CHEBI:33672") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "heterobicyclic compound") +SubClassOf( ) +SubClassOf( ) + # Class: (s-block molecular entity) AnnotationAssertion( "An s-block molecular entity is a molecular entity containing one or more atoms of an s-block element.") @@ -13054,6 +24462,19 @@ AnnotationAssertion(rdfs:label "p-b SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (d-block molecular entity) + +AnnotationAssertion( "A d-block molecular entity is a molecular entity containing one or more atoms of a d-block element.") +AnnotationAssertion(Annotation( "ChEBI") "d-block molecular entity") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "d-block compounds") +AnnotationAssertion(Annotation( "ChEBI") "d-block molecular entities") +AnnotationAssertion( "CHEBI:33676") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "d-block molecular entity") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (hydrides) AnnotationAssertion( "Hydrides are chemical compounds of hydrogen with other chemical elements.") @@ -13064,6 +24485,17 @@ AnnotationAssertion(rdfs:label "hyd SubClassOf( ) SubClassOf( ) +# Class: (oxygen hydride) + +AnnotationAssertion(Annotation( "ChEBI") "oxygen hydride") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "hydrides of oxygen") +AnnotationAssertion(Annotation( "ChEBI") "oxygen hydrides") +AnnotationAssertion( "CHEBI:33693") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "oxygen hydride") +SubClassOf( ) + # Class: (biomacromolecule) AnnotationAssertion( "A macromolecule formed by a living organism.") @@ -13092,6 +24524,47 @@ AnnotationAssertion( "information biomacromolecule") SubClassOf( ) +# Class: (nucleic acid) + +AnnotationAssertion( "A macromolecule made up of nucleotide units and hydrolysable into certain pyrimidine or purine bases (usually adenine, cytosine, guanine, thymine, uracil), D-ribose or 2-deoxy-D-ribose and phosphoric acid.") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "nucleic acids") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "NA") +AnnotationAssertion(Annotation( "ChEBI") "Nukleinsaeure") +AnnotationAssertion(Annotation( "ChEBI") "Nukleinsaeuren") +AnnotationAssertion(Annotation( "ChEBI") "acide nucleique") +AnnotationAssertion(Annotation( "ChEBI") "acides nucleiques") +AnnotationAssertion(Annotation( "ChEBI") "acido nucleico") +AnnotationAssertion(Annotation( "ChEBI") "acidos nucleicos") +AnnotationAssertion( "CHEBI:33696") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "nucleic acid") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (ribonucleic acid) + +AnnotationAssertion( "High molecular weight, linear polymers, composed of nucleotides containing ribose and linked by phosphodiester bonds; RNA is central to the synthesis of proteins.") +AnnotationAssertion(Annotation( "ChemIDplus") "CAS:63231-63-0") +AnnotationAssertion(Annotation( "IUPAC") "ribonucleic acid") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "ribonucleic acids") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "IUPAC") "RNA") +AnnotationAssertion(Annotation( "UniProt") "RNA") +AnnotationAssertion(Annotation( "ChEBI") "RNS") +AnnotationAssertion(Annotation( "ChEBI") "Ribonukleinsaeure") +AnnotationAssertion(Annotation( "ChemIDplus") "pentosenucleic acids") +AnnotationAssertion(Annotation( "ChEBI") "ribonucleic acids") +AnnotationAssertion(Annotation( "ChEBI") "ribose nucleic acid") +AnnotationAssertion(Annotation( "ChEBI") "yeast nucleic acid") +AnnotationAssertion( "CHEBI:33697") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "ribonucleic acid") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (proteinogenic amino-acid residue) AnnotationAssertion( "chebi_ontology") @@ -13145,6 +24618,18 @@ SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (gamma-amino acid) + +AnnotationAssertion( "A non-proteinogenic amino-acid in which the amino group is located on the carbon atom at the position gamma to the carboxy group.") +AnnotationAssertion(Annotation( "ChEBI") "gamma-amino acid") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "gamma-amino acids") +AnnotationAssertion( "CHEBI:33707") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "gamma-amino acid") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (amino-acid residue) AnnotationAssertion( "When two or more amino acids combine to form a peptide, the elements of water are removed, and what remains of each amino acid is called an amino-acid residue.") @@ -13209,6 +24694,72 @@ AnnotationAssertion(rdfs:label "car SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (iron group molecular entity) + +AnnotationAssertion(Annotation( "ChEBI") "iron group molecular entity") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "iron group molecular entities") +AnnotationAssertion( "CHEBI:33744") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "iron group molecular entity") +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (canonical nucleoside residue) + +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "canonical nucleoside residues") +AnnotationAssertion(Annotation( "CBN") "common nucleoside residues") +AnnotationAssertion(Annotation( "CBN") "nucleoside residue") +AnnotationAssertion(Annotation( "ChEBI") "standard nucleoside residues") +AnnotationAssertion( "CHEBI:33791") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "canonical nucleoside residue") +SubClassOf( ) + +# Class: (canonical ribonucleoside residue) + +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "CBN") "N") +AnnotationAssertion(Annotation( "CBN") "Nuc") +AnnotationAssertion(Annotation( "ChEBI") "canonical ribonucleoside residues") +AnnotationAssertion(Annotation( "CBN") "common ribonucleoside residue") +AnnotationAssertion(Annotation( "CBN") "common ribonucleoside residues") +AnnotationAssertion(Annotation( "ChEBI") "standard ribonucleoside residues") +AnnotationAssertion( "CHEBI:33792") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "canonical ribonucleoside residue") +SubClassOf( ) + +# Class: (canonical deoxyribonucleoside residue) + +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "canonical deoxyribonucleoside residues") +AnnotationAssertion(Annotation( "CBN") "common 2'-deoxyribonucleoside residue") +AnnotationAssertion(Annotation( "CBN") "common 2'-deoxyribonucleoside residues") +AnnotationAssertion(Annotation( "CBN") "dN") +AnnotationAssertion(Annotation( "CBN") "dNuc") +AnnotationAssertion(Annotation( "ChEBI") "standard deoxyribonucleoside residues") +AnnotationAssertion( "CHEBI:33793") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "canonical deoxyribonucleoside residue") +SubClassOf( ) + +# Class: (organic hydroxy compound) + +AnnotationAssertion( "An organic compound having at least one hydroxy group attached to a carbon atom.") +AnnotationAssertion( "CHEBI:64710") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "hydroxy compounds") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "organic alcohol") +AnnotationAssertion(Annotation( "ChEBI") "organic hydroxy compounds") +AnnotationAssertion( "CHEBI:33822") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "organic hydroxy compound") +SubClassOf( ) +SubClassOf( ) + # Class: (organic cyclic compound) AnnotationAssertion( "Any organic molecule that consists of atoms connected in the form of a ring.") @@ -13244,6 +24795,32 @@ AnnotationAssertion( "conjugated protein") SubClassOf( ) +# Class: (nucleoside) + +AnnotationAssertion( "An N-glycosyl compound that has both a nucleobase, normally adenine, guanine, xanthine, thymine, cytosine or uracil, and either a ribose or deoxyribose as functional parents.") +AnnotationAssertion( "0") +AnnotationAssertion( "C5H8O3R2") +AnnotationAssertion( "116.115") +AnnotationAssertion( "116.04734") +AnnotationAssertion( "[C@H]1([C@H]([C@@H](*)[C@@H](O1)*)O)CO") +AnnotationAssertion( "CHEBI:13661") +AnnotationAssertion( "CHEBI:25611") +AnnotationAssertion( "CHEBI:7647") +AnnotationAssertion( "KEGG:C00801") +AnnotationAssertion( "Wikipedia:Nucleoside") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Nucleoside") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "nucleosides") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "UniProt") "a nucleoside") +AnnotationAssertion(Annotation( "ChEBI") "nucleosides") +AnnotationAssertion( "CHEBI:33838") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "nucleoside") +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (macromolecule) AnnotationAssertion( "A macromolecule is a molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.") @@ -13259,6 +24836,32 @@ AnnotationAssertion( "macromolecule") SubClassOf( ) +# Class: (phenols) + +AnnotationAssertion( "Organic aromatic compounds having one or more hydroxy groups attached to a benzene or other arene ring.") +AnnotationAssertion( "0") +AnnotationAssertion( "C6HOR5") +AnnotationAssertion( "89.072") +AnnotationAssertion( "89.00274") +AnnotationAssertion( "C1(=C(C(=C(C(=C1*)*)*)*)*)O") +AnnotationAssertion( "CHEBI:13664") +AnnotationAssertion( "CHEBI:13825") +AnnotationAssertion( "CHEBI:25969") +AnnotationAssertion( "CHEBI:2857") +AnnotationAssertion( "KEGG:C15584") +AnnotationAssertion( "MetaCyc:Phenols") +AnnotationAssertion( "Wikipedia:Phenols") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "phenols") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Aryl alcohol") +AnnotationAssertion(Annotation( "UniProt") "a phenol") +AnnotationAssertion(Annotation( "IUPAC") "arenols") +AnnotationAssertion( "CHEBI:33853") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "phenols") +SubClassOf( ) +SubClassOf( ) + # Class: (reagent) AnnotationAssertion( "A substance used in a chemical reaction to detect, measure, examine, or produce other substances.") @@ -13272,6 +24875,32 @@ AnnotationAssertion( "reagent") SubClassOf( ) +# Class: (aldopentose) + +AnnotationAssertion( "A pentose with a (potential) aldehyde group at one end.") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:10723607") +AnnotationAssertion(Annotation( "ChEBI") "aldopentose") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "aldopentoses") +AnnotationAssertion( "CHEBI:33916") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "aldopentose") +SubClassOf( ) +SubClassOf( ) + +# Class: (aldohexose) + +AnnotationAssertion( "A hexose with a (potential) aldehyde group at one end.") +AnnotationAssertion( "CHEBI:2558") +AnnotationAssertion(Annotation( "ChEBI") "aldohexose") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "aldohexoses") +AnnotationAssertion( "CHEBI:33917") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "aldohexose") +SubClassOf( ) +SubClassOf( ) + # Class: (macronutrient) AnnotationAssertion( "Any nutrient required in large quantities by organisms throughout their life in order to orchestrate a range of physiological functions. Macronutrients are usually chemical elements (carbon, hydrogen, nitrogen, oxygen, phosphorus and sulfur) that humans consume in the largest quantities. Calcium, sodium, magnesium and potassium are sometimes included as macronutrients because they are required in relatively large quantities compared with other vitamins and minerals.") @@ -13282,6 +24911,44 @@ AnnotationAssertion( "macronutrient") SubClassOf( ) +# Class: (ribose) + +AnnotationAssertion( "Any aldopentose where the open-chain form has all the hydroxy groups on the same side in the Fischer projection. Occurrs in two enantiomeric forms, D- and L-ribose, of which only the former is found in nature.") +AnnotationAssertion( "0") +AnnotationAssertion( "C5H10O5") +AnnotationAssertion( "150.130") +AnnotationAssertion( "150.05282") +AnnotationAssertion( "CHEBI:26564") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "ribo-pentose") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "ribose") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "JCBN") "Rib") +AnnotationAssertion( "CHEBI:33942") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "ribose") +SubClassOf( ) + +# Class: (serotonin(1+)) + +AnnotationAssertion( "An ammonium ion that is the conjugate acid of serotonin; major species at pH 7.3.") +AnnotationAssertion( "+1") +AnnotationAssertion( "C10H13N2O") +AnnotationAssertion( "InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2/p+1") +AnnotationAssertion( "QZAYGJVTTNCVMB-UHFFFAOYSA-O") +AnnotationAssertion( "177.22250") +AnnotationAssertion( "177.10224") +AnnotationAssertion( "[NH3+]CCc1c[nH]c2ccc(O)cc12") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "2-(5-hydroxy-1H-indol-3-yl)ethanaminium") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "UniProt") "serotonin") +AnnotationAssertion(Annotation( "ChEBI") "serotonin cation") +AnnotationAssertion( "CHEBI:350546") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "serotonin(1+)") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (nitrogen hydride) AnnotationAssertion( "chebi_ontology") @@ -13302,6 +24969,15 @@ AnnotationAssertion( "azane") SubClassOf( ) +# Class: (aldose phosphate) + +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "aldose phosphates") +AnnotationAssertion( "CHEBI:35131") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "aldose phosphate") +SubClassOf( ) + # Class: ((6'R)-beta,epsilon-carotene) AnnotationAssertion( "0") @@ -13525,6 +25201,26 @@ AnnotationAssertion(rdfs:label "amm SubClassOf( ) SubClassOf( ) +# Class: (acylcholine) + +AnnotationAssertion( "A choline ester formed from choline and a carboxylic acid.") +AnnotationAssertion( "+1") +AnnotationAssertion( "C6H13NO2R") +AnnotationAssertion( "131.17290") +AnnotationAssertion( "131.09463") +AnnotationAssertion( "C[N+](C)(C)CCOC([*])=O") +AnnotationAssertion( "CHEBI:13245") +AnnotationAssertion( "CHEBI:22227") +AnnotationAssertion( "CHEBI:2463") +AnnotationAssertion( "KEGG:C01777") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "acylcholines") +AnnotationAssertion(Annotation( "UniProt") "an acylcholine") +AnnotationAssertion( "CHEBI:35287") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "acylcholine") +SubClassOf( ) + # Class: (steroid) AnnotationAssertion( "Any of naturally occurring compounds and synthetic analogues, based on the cyclopenta[a]phenanthrene carbon skeleton, partially or completely hydrogenated; there are usually methyl groups at C-10 and C-13, and often an alkyl group at C-17. By extension, one or more bond scissions, ring expansions and/or ring contractions of the skeleton may have occurred. Natural steroids are derived biogenetically from squalene which is a triterpene.") @@ -13548,6 +25244,80 @@ AnnotationAssertion(rdfs:label "ste SubClassOf( ) SubClassOf( ) +# Class: (17beta-hydroxy steroid) + +AnnotationAssertion( "A 17-hydroxy steroid in which the hydroxy group at position 17 has a beta-configuration.") +AnnotationAssertion( "0") +AnnotationAssertion( "C18H29OR") +AnnotationAssertion( "261.423") +AnnotationAssertion( "261.22184") +AnnotationAssertion( "CC12CCC3C(CCC4CCCCC34[*])C1CC[C@@H]2O") +AnnotationAssertion( "CHEBI:19176") +AnnotationAssertion( "CHEBI:794") +AnnotationAssertion( "KEGG:C03051") +AnnotationAssertion( "MetaCyc:17-beta-Hydroxysteroids") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "17beta-hydroxy steroids") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "17beta-hydroxysteroid") +AnnotationAssertion(Annotation( "ChEBI") "17beta-hydroxysteroids") +AnnotationAssertion(Annotation( "UniProt") "a 17beta-hydroxy steroid") +AnnotationAssertion( "CHEBI:35343") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "17beta-hydroxy steroid") +SubClassOf( ) + +# Class: (21-hydroxy steroid) + +AnnotationAssertion( "CHEBI:1300") +AnnotationAssertion( "CHEBI:13596") +AnnotationAssertion( "CHEBI:19803") +AnnotationAssertion( "KEGG:C02506") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "21-Hydroxysteroid") +AnnotationAssertion(Annotation( "ChEBI") "21-hydroxy steroids") +AnnotationAssertion(Annotation( "ChEBI") "21-hydroxysteroids") +AnnotationAssertion( "CHEBI:35344") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "21-hydroxy steroid") +SubClassOf( ) + +# Class: (11beta-hydroxy steroid) + +AnnotationAssertion( "Any 11-hydroxy steroid in which the hydroxy group at position 11 has beta- configuration.") +AnnotationAssertion( "0") +AnnotationAssertion( "C19H31OR") +AnnotationAssertion( "275.450") +AnnotationAssertion( "275.23749") +AnnotationAssertion( "C12(CCCCC1CCC3C2[C@H](CC4(C3CCC4*)C)O)C") +AnnotationAssertion( "CHEBI:13774") +AnnotationAssertion( "CHEBI:19134") +AnnotationAssertion( "CHEBI:738") +AnnotationAssertion( "KEGG:C01058") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "11beta-Hydroxysteroid") +AnnotationAssertion(Annotation( "ChEBI") "11beta-hydroxy steroids") +AnnotationAssertion(Annotation( "ChEBI") "11beta-hydroxysteroids") +AnnotationAssertion(Annotation( "UniProt") "an 11beta-hydroxysteroid") +AnnotationAssertion( "CHEBI:35346") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "11beta-hydroxy steroid") +SubClassOf( ) + +# Class: (hydroxy steroid) + +AnnotationAssertion( "CHEBI:24748") +AnnotationAssertion( "CHEBI:5814") +AnnotationAssertion( "KEGG:C02159") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Hydroxysteroid") +AnnotationAssertion(Annotation( "ChEBI") "hydroxy steroids") +AnnotationAssertion(Annotation( "ChEBI") "hydroxysteroids") +AnnotationAssertion( "CHEBI:35350") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "hydroxy steroid") +SubClassOf( ) +SubClassOf( ) + # Class: (organonitrogen compound) AnnotationAssertion( "Any heteroorganic entity containing at least one carbon-nitrogen bond.") @@ -13560,6 +25330,57 @@ AnnotationAssertion(rdfs:label "org SubClassOf( ) SubClassOf( ) +# Class: (fatty acid) + +AnnotationAssertion( "Any aliphatic monocarboxylic acid derived from or contained in esterified form in an animal or vegetable fat, oil or wax. Natural fatty acids commonly have a chain of 4 to 28 carbons (usually unbranched and even-numbered), which may be saturated or unsaturated. By extension, the term is sometimes used to embrace all acyclic aliphatic carboxylic acids.") +AnnotationAssertion( "0") +AnnotationAssertion( "CHO2R") +AnnotationAssertion( "45.01740") +AnnotationAssertion( "44.99765") +AnnotationAssertion( "OC([*])=O") +AnnotationAssertion( "CHEBI:13633") +AnnotationAssertion( "CHEBI:24024") +AnnotationAssertion( "CHEBI:4984") +AnnotationAssertion( "KEGG:C00162") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:14287444") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:14300208") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:14328676") +AnnotationAssertion( "Wikipedia:Fatty_acid") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Fatty acid") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "fatty acids") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "Fettsaeure") +AnnotationAssertion(Annotation( "ChEBI") "Fettsaeuren") +AnnotationAssertion(Annotation( "ChEBI") "acide gras") +AnnotationAssertion(Annotation( "ChemIDplus") "acides gras") +AnnotationAssertion(Annotation( "ChEBI") "acido graso") +AnnotationAssertion(Annotation( "ChEBI") "acidos grasos") +AnnotationAssertion(Annotation( "ChEBI") "fatty acids") +AnnotationAssertion( "CHEBI:35366") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "fatty acid") +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (monosaccharide) + +AnnotationAssertion( "Parent monosaccharides are polyhydroxy aldehydes H[CH(OH)]nC(=O)H or polyhydroxy ketones H-[CHOH]n-C(=O)[CHOH]m-H with three or more carbon atoms. The generic term 'monosaccharide' (as opposed to oligosaccharide or polysaccharide) denotes a single unit, without glycosidic connection to other such units. It includes aldoses, dialdoses, aldoketoses, ketoses and diketoses, as well as deoxy sugars, provided that the parent compound has a (potential) carbonyl group.") +AnnotationAssertion( "CHEBI:25407") +AnnotationAssertion( "CHEBI:6984") +AnnotationAssertion( "KEGG:C06698") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Monosaccharide") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "monosaccharides") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "Monosaccharid") +AnnotationAssertion(Annotation( "ChEBI") "Monosacharid") +AnnotationAssertion(Annotation( "ChEBI") "monosacarido") +AnnotationAssertion(Annotation( "IUPAC") "monosacaridos") +AnnotationAssertion( "CHEBI:35381") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "monosaccharide") +SubClassOf( ) + # Class: (oxoanion) AnnotationAssertion( "An oxoanion is an anion derived from an oxoacid by loss of hydron(s) bound to oxygen.") @@ -13575,6 +25396,32 @@ AnnotationAssertion(rdfs:label "oxo SubClassOf( ) SubClassOf( ) +# Class: (central nervous system drug) + +AnnotationAssertion( "A class of drugs producing both physiological and psychological effects through a variety of mechanisms involving the central nervous system.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "CNS agent") +AnnotationAssertion(Annotation( "ChEBI") "CNS drugs") +AnnotationAssertion(Annotation( "ChEBI") "central nervous system agents") +AnnotationAssertion( "CHEBI:35470") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "central nervous system drug") +SubClassOf( ) + +# Class: (anti-inflammatory drug) + +AnnotationAssertion( "A substance that reduces or suppresses inflammation.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "anti-inflammatory drugs") +AnnotationAssertion(Annotation( "ChEBI") "antiinflammatory agent") +AnnotationAssertion(Annotation( "ChEBI") "antiinflammatory drug") +AnnotationAssertion(Annotation( "ChEBI") "antiinflammatory drugs") +AnnotationAssertion( "CHEBI:35472") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "anti-inflammatory drug") +SubClassOf( ) +SubClassOf( ) + # Class: (alkali metal salt) AnnotationAssertion( "chebi_ontology") @@ -13585,6 +25432,27 @@ AnnotationAssertion(rdfs:label "alk SubClassOf( ) SubClassOf( ) +# Class: (analgesic) + +AnnotationAssertion( "An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion( "CHEBI:35480") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "analgesic") +SubClassOf( ) +SubClassOf( ) + +# Class: (central nervous system depressant) + +AnnotationAssertion( "A loosely defined group of drugs that tend to reduce the activity of the central nervous system.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "CNS depressants") +AnnotationAssertion(Annotation( "ChEBI") "central nervous system depressants") +AnnotationAssertion( "CHEBI:35488") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "central nervous system depressant") +SubClassOf( ) + # Class: (natural product fundamental parent) AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "natural product fundamental parents") @@ -13604,6 +25472,25 @@ AnnotationAssertion(rdfs:label "ste SubClassOf( ) SubClassOf( ) +# Class: (androstane) + +AnnotationAssertion( "0") +AnnotationAssertion( "C19H32") +AnnotationAssertion( "InChI=1S/C19H32/c1-18-11-5-7-16(18)15-9-8-14-6-3-4-12-19(14,2)17(15)10-13-18/h14-17H,3-13H2,1-2H3/t14?,15-,16-,17-,18-,19-/m0/s1") +AnnotationAssertion( "QZLYKIGBANMMBK-FZFXZXLVSA-N") +AnnotationAssertion( "260.45738") +AnnotationAssertion( "260.25040") +AnnotationAssertion( "[H][C@@]12CCC3CCCC[C@]3(C)[C@@]1([H])CC[C@]1(C)CCC[C@@]21[H]") +AnnotationAssertion(Annotation( "Beilstein") "Beilstein:5247532") +AnnotationAssertion(Annotation( "ChemIDplus") "CAS:24887-75-0") +AnnotationAssertion(Annotation( "LIPID MAPS") "LIPID_MAPS_instance:LMST02020000") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "androstane") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion( "CHEBI:35509") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "androstane") +SubClassOf( ) + # Class: (cholane) AnnotationAssertion( "0") @@ -13620,6 +25507,54 @@ AnnotationAssertion( "cholane") SubClassOf( ) +# Class: (beta-adrenergic agonist) + +AnnotationAssertion( "An agent that selectively binds to and activates beta-adrenergic receptors.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "beta-adrenergic agonists") +AnnotationAssertion(Annotation( "ChEBI") "beta-adrenergic receptor agonist") +AnnotationAssertion(Annotation( "IUPHAR") "beta-adrenoceptor agonists") +AnnotationAssertion( "CHEBI:35522") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "beta-adrenergic agonist") +SubClassOf( ) +SubClassOf( ) + +# Class: (bronchodilator agent) + +AnnotationAssertion( "An agent that causes an increase in the expansion of a bronchus or bronchial tubes.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "bronchodilator") +AnnotationAssertion(Annotation( "ChEBI") "bronchodilator agents") +AnnotationAssertion(Annotation( "ChEBI") "broncholytic agent") +AnnotationAssertion( "CHEBI:35523") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "bronchodilator agent") +SubClassOf( ) + +# Class: (sympathomimetic agent) + +AnnotationAssertion( "A drug that mimics the effects of stimulating postganglionic adrenergic sympathetic nerves. Included in this class are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "sympathomimetic") +AnnotationAssertion(Annotation( "ChEBI") "sympathomimetics") +AnnotationAssertion( "CHEBI:35524") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "sympathomimetic agent") +SubClassOf( ) + +# Class: (heterocyclic organic fundamental parent) + +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "heterocyclic parent hydrides") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "heterocyclic fundamental parent") +AnnotationAssertion(Annotation( "ChEBI") "heterocyclic organic fundamental parents") +AnnotationAssertion(Annotation( "ChEBI") "organic heterocyclic fundamental parents") +AnnotationAssertion( "CHEBI:35552") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "heterocyclic organic fundamental parent") +SubClassOf( ) + # Class: (cardiovascular drug) AnnotationAssertion( "A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume.") @@ -13631,6 +25566,155 @@ AnnotationAssertion( "cardiovascular drug") SubClassOf( ) +# Class: (mancude ring) + +AnnotationAssertion( "Any molecular entity that consists of a ring having (formally) the maximum number of noncumulative double bonds.") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "mancude-ring systems") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "mancude rings") +AnnotationAssertion(Annotation( "IUPAC") "mancunide-ring systems") +AnnotationAssertion( "CHEBI:35568") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "mancude ring") +SubClassOf( ) + +# Class: (alpha-adrenergic agonist) + +AnnotationAssertion( "An agent that selectively binds to and activates alpha-adrenergic receptors.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "alpha-adrenergic agonists") +AnnotationAssertion(Annotation( "ChEBI") "alpha-adrenergic receptor agonist") +AnnotationAssertion(Annotation( "IUPHAR") "alpha-adrenoceptor agonists") +AnnotationAssertion( "CHEBI:35569") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "alpha-adrenergic agonist") +SubClassOf( ) +SubClassOf( ) + +# Class: (mancude organic heterobicyclic parent) + +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "mancude organic heterobicyclic parents") +AnnotationAssertion(Annotation( "ChEBI") "mancude-ring organic heterobicyclic parents") +AnnotationAssertion( "CHEBI:35570") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "mancude organic heterobicyclic parent") +SubClassOf( ) +SubClassOf( ) + +# Class: (mancude organic heterocyclic parent) + +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "mancude organic heterocyclic parents") +AnnotationAssertion(Annotation( "ChEBI") "mancude-ring organic heterocyclic parents") +AnnotationAssertion( "CHEBI:35571") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "mancude organic heterocyclic parent") +SubClassOf( ) +SubClassOf( ) + +# Class: (organic mancude parent) + +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "organic mancude parents") +AnnotationAssertion(Annotation( "ChEBI") "organic mancude-ring parents") +AnnotationAssertion( "CHEBI:35573") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "organic mancude parent") +SubClassOf( ) +SubClassOf( ) + +# Class: (purine) + +AnnotationAssertion( "A heterobicyclic aromatic organic compound comprising a pyrimidine ring fused to an imidazole ring; the parent compound of the purines.") +AnnotationAssertion( "0") +AnnotationAssertion( "C5H4N4") +AnnotationAssertion( "120.112") +AnnotationAssertion( "120.04360") +AnnotationAssertion( "HMDB:HMDB0001366") +AnnotationAssertion( "KEGG:C15587") +AnnotationAssertion( "MetaCyc:PURINE") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:12865945") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:24088627") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "purine") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion( "CHEBI:35584") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "purine") +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (1H-purine) + +AnnotationAssertion( "The 1H-tautomer of purine.") +AnnotationAssertion( "0") +AnnotationAssertion( "C5H4N4") +AnnotationAssertion( "InChI=1S/C5H4N4/c1-4-5(8-2-6-1)9-3-7-4/h1-3H,(H,6,7,8,9)") +AnnotationAssertion( "KDCGOANMDULRCW-UHFFFAOYSA-N") +AnnotationAssertion( "120.11210") +AnnotationAssertion( "120.04360") +AnnotationAssertion( "c1nc2c[nH]cnc2n1") +AnnotationAssertion(Annotation( "Gmelin") "Gmelin:2379911") +AnnotationAssertion(Annotation( "ChEBI") "1H-purine") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion( "CHEBI:35586") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "1H-purine") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (3H-purine) + +AnnotationAssertion( "The 3H-tautomer of purine.") +AnnotationAssertion( "0") +AnnotationAssertion( "C5H4N4") +AnnotationAssertion( "InChI=1S/C5H4N4/c1-4-5(8-2-6-1)9-3-7-4/h1-3H,(H,6,7,8,9)") +AnnotationAssertion( "KDCGOANMDULRCW-UHFFFAOYSA-N") +AnnotationAssertion( "120.11222") +AnnotationAssertion( "120.04360") +AnnotationAssertion( "c1nc2cnc[nH]c2n1") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:6149478") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:7178185") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:7296170") +AnnotationAssertion(Annotation( "Reaxys") "Reaxys:1210196") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "3H-purine") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion( "CHEBI:35588") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "3H-purine") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (9H-purine) + +AnnotationAssertion( "The 9H-tautomer of purine.") +AnnotationAssertion( "0") +AnnotationAssertion( "C5H4N4") +AnnotationAssertion( "InChI=1S/C5H4N4/c1-4-5(8-2-6-1)9-3-7-4/h1-3H,(H,6,7,8,9)") +AnnotationAssertion( "KDCGOANMDULRCW-UHFFFAOYSA-N") +AnnotationAssertion( "120.11222") +AnnotationAssertion( "120.04360") +AnnotationAssertion( "c1ncc2nc[nH]c2n1") +AnnotationAssertion(Annotation( "Beilstein") "Beilstein:606899") +AnnotationAssertion(Annotation( "NIST Chemistry WebBook") "CAS:120-73-0") +AnnotationAssertion(Annotation( "Gmelin") "Gmelin:3120") +AnnotationAssertion( "Wikipedia:Purine") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "9H-purine") +AnnotationAssertion(Annotation( "UniProt") "9H-purine") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion( "CHEBI:35589") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "9H-purine") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (carbon oxoanion) AnnotationAssertion( "A negative ion consisting solely of carbon and oxygen atoms, and therefore having the general formula CxOy(n-) for some integers x, y and n.") @@ -13668,6 +25752,30 @@ AnnotationAssertion( "vasodilator agent") SubClassOf( ) +# Class: (anticonvulsant) + +AnnotationAssertion( "A drug used to prevent seizures or reduce their severity.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "Antiepileptika") +AnnotationAssertion(Annotation( "ChEBI") "Antiepileptikum") +AnnotationAssertion(Annotation( "ChEBI") "Antikonvulsiva") +AnnotationAssertion(Annotation( "ChEBI") "Antikonvulsivum") +AnnotationAssertion(Annotation( "ChEBI") "anti-convulsant") +AnnotationAssertion(Annotation( "ChEBI") "anti-convulsants") +AnnotationAssertion(Annotation( "ChEBI") "anti-convulsive agent") +AnnotationAssertion(Annotation( "ChEBI") "anti-convulsive agents") +AnnotationAssertion(Annotation( "ChEBI") "anticonvulsants") +AnnotationAssertion(Annotation( "ChEBI") "anticonvulsive agent") +AnnotationAssertion(Annotation( "ChEBI") "anticonvulsive agents") +AnnotationAssertion(Annotation( "ChEBI") "antiepileptic") +AnnotationAssertion(Annotation( "ChEBI") "antiepileptics") +AnnotationAssertion(Annotation( "ChEBI") "antiepileptique") +AnnotationAssertion(Annotation( "ChEBI") "antiepileptiques") +AnnotationAssertion( "CHEBI:35623") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "anticonvulsant") +SubClassOf( ) + # Class: (dicarboxylic acid) AnnotationAssertion( "Any carboxylic acid containing two carboxy groups.") @@ -13745,6 +25853,30 @@ AnnotationAssertion(rdfs:label "lip SubClassOf( ) SubClassOf( ) +# Class: (monocarboxylic acid anion) + +AnnotationAssertion( "A carboxylic acid anion formed when the carboxy group of a monocarboxylic acid is deprotonated.") +AnnotationAssertion( "-1") +AnnotationAssertion( "CO2R") +AnnotationAssertion( "44.01000") +AnnotationAssertion( "43.98983") +AnnotationAssertion( "[O-]C([*])=O") +AnnotationAssertion( "CHEBI:13657") +AnnotationAssertion( "CHEBI:25382") +AnnotationAssertion( "CHEBI:3407") +AnnotationAssertion( "KEGG:C00060") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Carboxylate") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Monocarboxylate") +AnnotationAssertion(Annotation( "UniProt") "a monocarboxylate") +AnnotationAssertion(Annotation( "ChEBI") "monocarboxylates") +AnnotationAssertion(Annotation( "ChEBI") "monocarboxylic acid anions") +AnnotationAssertion( "CHEBI:35757") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "monocarboxylic acid anion") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (phosphate ion) AnnotationAssertion( "A phosphorus oxoanion that is the conjugate base of phosphoric acid.") @@ -13771,6 +25903,21 @@ AnnotationAssertion(rdfs:label "pho SubClassOf( ) SubClassOf( ) +# Class: (oxo steroid) + +AnnotationAssertion( "CHEBI:24979") +AnnotationAssertion( "CHEBI:25804") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "keto steroids") +AnnotationAssertion(Annotation( "ChEBI") "ketosteroids") +AnnotationAssertion(Annotation( "ChEBI") "oxo steroids") +AnnotationAssertion(Annotation( "ChEBI") "oxosteroids") +AnnotationAssertion( "CHEBI:35789") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "oxo steroid") +SubClassOf( ) +SubClassOf( ) + # Class: (tetrapyrrole fundamental parent) AnnotationAssertion( "chebi_ontology") @@ -13781,6 +25928,17 @@ AnnotationAssertion(rdfs:label "tet SubClassOf( ) SubClassOf( ) +# Class: (imidazopyrimidine) + +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "imidazopyrimidines") +AnnotationAssertion( "CHEBI:35875") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "imidazopyrimidine") +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + # Class: (pnictogen hydride) AnnotationAssertion(Annotation( "ChEBI") "pnictogen hydride") @@ -13792,6 +25950,17 @@ AnnotationAssertion(rdfs:label "pni SubClassOf( ) SubClassOf( ) +# Class: (neurotransmitter agent) + +AnnotationAssertion( "A substance used for its pharmacological action on any aspect of neurotransmitter systems. Neurotransmitter agents include agonists, antagonists, degradation inhibitors, uptake inhibitors, depleters, precursors, and modulators of receptor function.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "neurotransmitter agents") +AnnotationAssertion( "CHEBI:35942") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "neurotransmitter agent") +SubClassOf( ) +SubClassOf( ) + # Class: (cholanoid) AnnotationAssertion( "CHEBI:22867") @@ -13819,6 +25988,72 @@ AnnotationAssertion(rdfs:label "pro SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (bile acid anion) + +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "bile acid anions") +AnnotationAssertion( "CHEBI:36235") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "bile acid anion") +SubClassOf( ) +SubClassOf( ) + +# Class: (cholanic acid) + +AnnotationAssertion( "A steroid acid that consists of cholane having a carboxy group in place of the methyl group at position 24.") +AnnotationAssertion( "0") +AnnotationAssertion( "C24H40O2") +AnnotationAssertion( "InChI=1S/C24H40O2/c1-16(7-12-22(25)26)19-10-11-20-18-9-8-17-6-4-5-14-23(17,2)21(18)13-15-24(19,20)3/h16-21H,4-15H2,1-3H3,(H,25,26)/t16-,17?,18+,19-,20+,21+,23+,24-/m1/s1") +AnnotationAssertion( "RPKLZQLYODPWTM-KBMWBBLPSA-N") +AnnotationAssertion( "360.57320") +AnnotationAssertion( "360.30283") +AnnotationAssertion( "[H][C@@]1(CC[C@@]2([H])[C@]3([H])CCC4CCCC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)CCC(O)=O") +AnnotationAssertion(Annotation( "ChemIDplus") "CAS:25312-65-6") +AnnotationAssertion( "Patent:JP2008069152") +AnnotationAssertion(Annotation( "Reaxys") "Reaxys:13246008") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "cholan-24-oic acid") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion( "CHEBI:36237") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "cholanic acid") +SubClassOf( ) + +# Class: (5beta-cholanic acid) + +AnnotationAssertion( "0") +AnnotationAssertion( "C24H40O2") +AnnotationAssertion( "InChI=1S/C24H40O2/c1-16(7-12-22(25)26)19-10-11-20-18-9-8-17-6-4-5-14-23(17,2)21(18)13-15-24(19,20)3/h16-21H,4-15H2,1-3H3,(H,25,26)/t16-,17+,18+,19-,20+,21+,23+,24-/m1/s1") +AnnotationAssertion( "RPKLZQLYODPWTM-LVVAJZGHSA-N") +AnnotationAssertion( "360.57320") +AnnotationAssertion( "360.30283") +AnnotationAssertion( "[H][C@@]12CCCC[C@]1(C)[C@@]1([H])CC[C@]3(C)[C@]([H])(CC[C@@]3([H])[C@]1([H])CC2)[C@H](C)CCC(O)=O") +AnnotationAssertion(Annotation( "Beilstein") "Beilstein:3214794") +AnnotationAssertion(Annotation( "ChemIDplus") "CAS:546-18-9") +AnnotationAssertion(Annotation( "LIPID MAPS") "LIPID_MAPS_instance:LMST04010441") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "5beta-cholan-24-oic acid") +AnnotationAssertion(Annotation( "ChemIDplus") "5beta-cholanic acid") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChemIDplus") "(5beta)-cholan-24-oic acid") +AnnotationAssertion(Annotation( "ChemIDplus") "(5beta,17beta)-gamma-methylandrostane-17-butanoic acid") +AnnotationAssertion(Annotation( "ChemIDplus") "5beta-cholanoic acid") +AnnotationAssertion(Annotation( "ChemIDplus") "ursocholanic acid") +AnnotationAssertion( "CHEBI:36238") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "5beta-cholanic acid") +SubClassOf( ) +SubClassOf( ) + +# Class: (5beta-cholanic acids) + +AnnotationAssertion( "Members of the class of cholanic acids based on a 5beta-cholane skeleton.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion( "CHEBI:36248") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "5beta-cholanic acids") +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (bile acid salt) AnnotationAssertion( "A salt of a bile acid.") @@ -13830,6 +26065,17 @@ AnnotationAssertion(rdfs:label "bil SubClassOf( ) SubClassOf( ) +# Class: (cholanic acids) + +AnnotationAssertion( "CHEBI:23166") +AnnotationAssertion( "CHEBI:23211") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion( "CHEBI:36278") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "cholanic acids") +SubClassOf( ) +SubClassOf( ) + # Class: (cyclic tetrapyrrole) AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "macrocyclic tetrapyrroles") @@ -13875,6 +26121,17 @@ AnnotationAssertion( "fermion") SubClassOf( ) +# Class: (boson) + +AnnotationAssertion( "Particle of integer spin quantum number following Bose-Einstein statistics. Bosons are named after Satyendra Nath Bose.") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "boson") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "bosons") +AnnotationAssertion( "CHEBI:36341") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "boson") +SubClassOf( ) + # Class: (subatomic particle) AnnotationAssertion( "A particle smaller than an atom.") @@ -14027,6 +26284,18 @@ AnnotationAssertion(rdfs:label "org SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (corticosteroid hormone) + +AnnotationAssertion( "Any of a class of steroid hormones that are produced in the adrenal cortex.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "adrenal cortex hormones") +AnnotationAssertion(Annotation( "ChEBI") "corticosteroid hormones") +AnnotationAssertion( "CHEBI:36699") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "corticosteroid hormone") +SubClassOf( ) +SubClassOf( ) + # Class: (phosphocholines) AnnotationAssertion( "Any compound having phosphocholine as part of its structure.") @@ -14091,6 +26360,55 @@ AnnotationAssertion(rdfs:label "far SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (17-hydroxy steroid) + +AnnotationAssertion( "A hydroxy steroid carrying a hydroxy group at position 17.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "17-hydroxy steroids") +AnnotationAssertion( "CHEBI:36838") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "17-hydroxy steroid") +SubClassOf( ) + +# Class: (11-hydroxy steroid) + +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "11-hydroxy steroids") +AnnotationAssertion( "CHEBI:36841") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "11-hydroxy steroid") +SubClassOf( ) + +# Class: (20-oxo steroid) + +AnnotationAssertion( "An oxo steroid carrying an oxo group at position 20.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "20-oxo steroids") +AnnotationAssertion( "CHEBI:36885") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "20-oxo steroid") +SubClassOf( ) + +# Class: (18-oxo steroid) + +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "18-oxo steroids") +AnnotationAssertion( "CHEBI:36887") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "18-oxo steroid") +SubClassOf( ) + +# Class: (chalcogen hydride) + +AnnotationAssertion(Annotation( "ChEBI") "chalcogen hydride") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "chalcogen hydrides") +AnnotationAssertion( "CHEBI:36902") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "chalcogen hydride") +SubClassOf( ) +SubClassOf( ) + # Class: (inorganic ion) AnnotationAssertion( "chebi_ontology") @@ -14166,6 +26484,32 @@ AnnotationAssertion(rdfs:label "org SubClassOf( ) SubClassOf( ) +# Class: (nucleotide) + +AnnotationAssertion( "A nucleotide is a nucleoside phosphate resulting from the condensation of the 3 or 5 hydroxy group of a nucleoside with phosphoric acid.") +AnnotationAssertion( "CHEBI:13215") +AnnotationAssertion( "CHEBI:13663") +AnnotationAssertion( "CHEBI:7656") +AnnotationAssertion( "KEGG:C00215") +AnnotationAssertion( "Wikipedia:Nucleotide") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Nucleotide") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "nucleotides") +AnnotationAssertion( "CHEBI:36976") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "nucleotide") +SubClassOf( ) + +# Class: (ribonucleoside 5'-phosphate) + +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "ribonucleoside 5'-phosphates") +AnnotationAssertion( "CHEBI:37015") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "ribonucleoside 5'-phosphate") +SubClassOf( ) +SubClassOf( ) + # Class: (amino-acid anion) AnnotationAssertion(Annotation( "ChEBI") "amino-acid anion") @@ -14179,6 +26523,84 @@ SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (purine ribonucleoside 5'-diphosphate) + +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "purine ribonucleoside 5'-diphosphates") +AnnotationAssertion( "CHEBI:37038") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "purine ribonucleoside 5'-diphosphate") +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (purine ribonucleoside 5'-triphosphate) + +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "purine ribonucleoside 5'-triphosphates") +AnnotationAssertion( "CHEBI:37045") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "purine ribonucleoside 5'-triphosphate") +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (ribonucleoside 5'-diphosphate) + +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "ribonucleoside 5'-diphosphates") +AnnotationAssertion( "CHEBI:37075") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "ribonucleoside 5'-diphosphate") +SubClassOf( ) + +# Class: (ribonucleoside 5'-triphosphate) + +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "ribonucleoside 5'-triphosphates") +AnnotationAssertion( "CHEBI:37076") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "ribonucleoside 5'-triphosphate") +SubClassOf( ) + +# Class: (adenosine 5'-phosphate) + +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "adenosine 5'-phosphates") +AnnotationAssertion( "CHEBI:37096") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "adenosine 5'-phosphate") +SubClassOf( ) + +# Class: (glucan) + +AnnotationAssertion( "A polysaccharide composed of glucose residues.") +AnnotationAssertion( "C12H22O11(C6H10O5)n") +AnnotationAssertion( "CHEBI:24255") +AnnotationAssertion( "CHEBI:5392") +AnnotationAssertion(Annotation( "ChemIDplus") "CAS:9037-91-6") +AnnotationAssertion( "KEGG:C01379") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Glucan") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "glucan") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "glucans") +AnnotationAssertion( "CHEBI:37163") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "glucan") +SubClassOf( ) + +# Class: (homopolysaccharide) + +AnnotationAssertion( "Glycans composed of a single type of monosaccharide residue. They are named by replacing the ending '-ose' of the sugar by '-an'.") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "homopolysaccharide") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "IUPAC") "homoglycan") +AnnotationAssertion(Annotation( "ChEBI") "homopolysaccharides") +AnnotationAssertion( "CHEBI:37164") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "homopolysaccharide") +SubClassOf( ) + # Class: (organic hydride) AnnotationAssertion( "chebi_ontology") @@ -14225,6 +26647,21 @@ AnnotationAssertion( "mucopolysaccharide") SubClassOf( ) +# Class: (proteoglycan) + +AnnotationAssertion( "A glycoprotein in which the carbohydrate units are polysaccharides that contain amino sugars. The protein is glycosylated by one or more (up to about 100) glycosaminoglycans.") +AnnotationAssertion( "CHEBI:26351") +AnnotationAssertion( "CHEBI:8582") +AnnotationAssertion( "KEGG:C00866") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Proteoglycan") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "proteoglycans") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion( "CHEBI:37396") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "proteoglycan") +SubClassOf( ) +SubClassOf( ) + # Class: (chondroitin sulfate) AnnotationAssertion( "Any of a class of 10--60 kDa glycosaminoglycan sulfates, widely distributed in cartilage and other mammalian connective tissues.") @@ -14337,6 +26774,45 @@ AnnotationAssertion(rdfs:label "car SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (adrenergic agonist) + +AnnotationAssertion( "An agent that selectively binds to and activates adrenergic receptors.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "adrenergic agonists") +AnnotationAssertion(Annotation( "ChEBI") "adrenergic receptor agonist") +AnnotationAssertion(Annotation( "IUPHAR") "adrenoceptor agonists") +AnnotationAssertion(Annotation( "ChEBI") "adrenomimetic") +AnnotationAssertion(Annotation( "ChEBI") "adrenomimetics") +AnnotationAssertion( "CHEBI:37886") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "adrenergic agonist") +SubClassOf( ) + +# Class: (adrenergic agent) + +AnnotationAssertion( "Any agent that acts on an adrenergic receptor or affects the life cycle of an adrenergic transmitter.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "adrenergic agents") +AnnotationAssertion(Annotation( "ChEBI") "adrenergic drug") +AnnotationAssertion(Annotation( "ChEBI") "adrenergic drugs") +AnnotationAssertion(Annotation( "ChEBI") "adrenergic neuron agents") +AnnotationAssertion(Annotation( "ChEBI") "adrenergics") +AnnotationAssertion( "CHEBI:37962") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "adrenergic agent") +SubClassOf( ) + +# Class: (anti-arrhythmia drug) + +AnnotationAssertion( "A drug used for the treatment or prevention of cardiac arrhythmias. Anti-arrhythmia drugs may affect the polarisation-repolarisation phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibres.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "anti-arrhythmia agent") +AnnotationAssertion(Annotation( "ChEBI") "antiarrhythmic agent") +AnnotationAssertion( "CHEBI:38070") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "anti-arrhythmia drug") +SubClassOf( ) + # Class: (polypyrrole) AnnotationAssertion( "A compound composed of two or more pyrrole units.") @@ -14362,6 +26838,100 @@ AnnotationAssertion(rdfs:label "org SubClassOf( ) SubClassOf( ) +# Class: (oxacycle) + +AnnotationAssertion( "Any organic heterocyclic compound containing at least one ring oxygen atom.") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:17134300") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "heterocyclic organooxygen compounds") +AnnotationAssertion(Annotation( "ChEBI") "organooxygen heterocyclic compounds") +AnnotationAssertion(Annotation( "ChEBI") "oxacycles") +AnnotationAssertion( "CHEBI:38104") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "oxacycle") +SubClassOf( ) +SubClassOf( ) + +# Class: (cardiotonic drug) + +AnnotationAssertion( "A drug that has a strengthening effect on the heart or that can increase cardiac output.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "cardiotonic drugs") +AnnotationAssertion( "CHEBI:38147") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "cardiotonic drug") +SubClassOf( ) + +# Class: (organic heteropolycyclic compound) + +AnnotationAssertion( "CHEBI:25429") +AnnotationAssertion( "CHEBI:38075") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "organic heteropolycyclic compounds") +AnnotationAssertion( "CHEBI:38166") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "organic heteropolycyclic compound") +SubClassOf( ) +SubClassOf( ) + +# Class: (monocyclic heteroarene) + +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "monocyclic heteroarenes") +AnnotationAssertion( "CHEBI:38179") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "monocyclic heteroarene") +SubClassOf( ) + +# Class: (polycyclic heteroarene) + +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "polycyclic heteroarenes") +AnnotationAssertion( "CHEBI:38180") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "polycyclic heteroarene") +SubClassOf( ) + +# Class: (cholinergic drug) + +AnnotationAssertion( "Any drug used for its actions on cholinergic systems. Included here are agonists and antagonists, drugs that affect the life cycle of acetylcholine, and drugs that affect the survival of cholinergic neurons.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "cholinergic agent") +AnnotationAssertion(Annotation( "ChEBI") "cholinergic drugs") +AnnotationAssertion(Annotation( "ChEBI") "cholinomimetic") +AnnotationAssertion( "CHEBI:38323") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "cholinergic drug") +SubClassOf( ) + +# Class: (cholinergic agonist) + +AnnotationAssertion( "Any drug that binds to and activates cholinergic receptors.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "acetylcholine agonist") +AnnotationAssertion(Annotation( "ChEBI") "acetylcholine agonists") +AnnotationAssertion(Annotation( "IUPHAR") "acetylcholine receptor agonist") +AnnotationAssertion(Annotation( "ChEBI") "cholinergic agonists") +AnnotationAssertion(Annotation( "ChEBI") "cholinomimetic") +AnnotationAssertion(Annotation( "ChEBI") "cholinomimetics") +AnnotationAssertion( "CHEBI:38324") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "cholinergic agonist") +SubClassOf( ) + +# Class: (muscarinic agonist) + +AnnotationAssertion( "Any drug that binds to and activates a muscarinic cholinergic receptor.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "muscarinic acetylcholine receptor agonist") +AnnotationAssertion(Annotation( "ChEBI") "muscarinic agonists") +AnnotationAssertion(Annotation( "ChEBI") "muscarinic cholinergic agonist") +AnnotationAssertion(Annotation( "ChEBI") "muscarinic cholinergic agonists") +AnnotationAssertion( "CHEBI:38325") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "muscarinic agonist") +SubClassOf( ) + # Class: (simple protein) AnnotationAssertion( "chebi_ontology") @@ -14371,6 +26941,17 @@ AnnotationAssertion( "simple protein") SubClassOf( ) +# Class: (aminoalkylindole) + +AnnotationAssertion( "CHEBI:22503") +AnnotationAssertion( "CHEBI:24792") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "aminoalkylindoles") +AnnotationAssertion( "CHEBI:38631") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "aminoalkylindole") +SubClassOf( ) + # Class: (organic sodium salt) AnnotationAssertion(Annotation( "ChEBI") "organic sodium salt") @@ -14409,6 +26990,58 @@ AnnotationAssertion( "anaesthetic") SubClassOf( ) +# Class: (corticotropin) + +AnnotationAssertion( "A polypeptide hormone produced and secreted by the pituitary gland comprising 39 amino acid residues coupled in a linear sequence. The N-terminal 24-amino acid segment is identical in all species and contains the adrenocorticotrophic activity. Corticotropin stimulates the cortex of the adrenal gland and boosts the synthesis of corticosteroids, mainly glucocorticoids but also sex steroids (androgens). It is used in the treatment of certain neurological disorders such as infantile spasms and multiple sclerosis, and diagnostically to investigate adrenocortical insufficiency.") +AnnotationAssertion( "0") +AnnotationAssertion( "C207H308N56O58S") +AnnotationAssertion( "InChI=1S/C207H308N56O58S/c1-108(2)89-140(186(302)240-135(69-74-163(279)280)182(298)254-149(204(320)321)94-117-43-20-15-21-44-117)250-193(309)152-54-35-86-262(152)202(318)147(92-116-41-18-14-19-42-116)252-171(287)114(11)230-175(291)132(66-71-160(273)274)234-170(286)113(10)231-191(307)150(105-265)255-183(299)136(70-75-164(281)282)241-190(306)146(98-165(283)284)249-180(296)133(67-72-161(275)276)235-169(285)112(9)229-157(270)101-225-174(290)145(97-156(213)269)251-194(310)153-55-36-87-263(153)203(319)148(93-119-60-64-123(268)65-61-119)253-199(315)167(110(5)6)257-185(301)129(49-26-30-79-210)243-198(314)168(111(7)8)259-196(312)155-57-38-85-261(155)201(317)139(53-34-83-223-207(218)219)244-178(294)130(51-32-81-221-205(214)215)237-177(293)128(48-25-29-78-209)236-176(292)127(47-24-28-77-208)232-158(271)103-227-197(313)166(109(3)4)258-195(311)154-56-37-84-260(154)200(316)138(50-27-31-80-211)233-159(272)102-226-173(289)143(95-120-99-224-126-46-23-22-45-124(120)126)247-179(295)131(52-33-82-222-206(216)217)238-187(303)142(90-115-39-16-13-17-40-115)246-189(305)144(96-121-100-220-107-228-121)248-181(297)134(68-73-162(277)278)239-184(300)137(76-88-322-12)242-192(308)151(106-266)256-188(304)141(245-172(288)125(212)104-264)91-118-58-62-122(267)63-59-118/h13-23,39-46,58-65,99-100,107-114,125,127-155,166-168,224,264-268H,24-38,47-57,66-98,101-106,208-212H2,1-12H3,(H2,213,269)(H,220,228)(H,225,290)(H,226,289)(H,227,313)(H,229,270)(H,230,291)(H,231,307)(H,232,271)(H,233,272)(H,234,286)(H,235,285)(H,236,292)(H,237,293)(H,238,303)(H,239,300)(H,240,302)(H,241,306)(H,242,308)(H,243,314)(H,244,294)(H,245,288)(H,246,305)(H,247,295)(H,248,297)(H,249,296)(H,250,309)(H,251,310)(H,252,287)(H,253,315)(H,254,298)(H,255,299)(H,256,304)(H,257,301)(H,258,311)(H,259,312)(H,273,274)(H,275,276)(H,277,278)(H,279,280)(H,281,282)(H,283,284)(H,320,321)(H4,214,215,221)(H4,216,217,222)(H4,218,219,223)/t112-,113-,114-,125-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,144-,145-,146-,147-,148-,149-,150-,151-,152-,153-,154-,155-,166-,167-,168-/m0/s1") +AnnotationAssertion( "IDLFZVILOHSSID-OVLDLUHVSA-N") +AnnotationAssertion( "4541.06600") +AnnotationAssertion( "4538.25937") +AnnotationAssertion( "CSCC[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](N)CO)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(O)=O") +AnnotationAssertion(Annotation( "ChemIDplus") "CAS:9002-60-2") +AnnotationAssertion(Annotation( "KEGG COMPOUND") "CAS:9002-60-2") +AnnotationAssertion( "DrugBank:DB01285") +AnnotationAssertion(Annotation( "DrugCentral") "Drug_Central:4931") +AnnotationAssertion( "KEGG:C02017") +AnnotationAssertion( "KEGG:D00146") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Corticotropin") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "L-seryl-L-tyrosyl-L-seryl-L-methionyl-L-alpha-glutamyl-L-histidyl-L-phenylalanyl-L-arginyl-L-tryptophylglycyl-L-lysyl-L-prolyl-L-valylglycyl-L-lysyl-L-lysyl-L-arginyl-L-arginyl-L-prolyl-L-valyl-L-lysyl-L-valyl-L-tyrosyl-L-prolyl-L-alpha-aspartylglycyl-L-alanyl-L-alpha-glutamyl-L-alpha-aspartyl-L-alpha-glutamyl-L-seryl-L-alanyl-L-alpha-glutamyl-L-alanyl-L-phenylalanyl-L-prolyl-L-leucyl-L-alpha-glutamyl-L-phenylalanine") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "ACTH") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Adrenocorticotropic hormone") +AnnotationAssertion(Annotation( "DrugBank") "SYSMEHFRWGKPVGKKRRPVKVYPDGAEDQLAEAFPLEF") +AnnotationAssertion(Annotation( "ChemIDplus") "adrenocorticotropin") +AnnotationAssertion(Annotation( "ChemIDplus") Annotation( ) "corticotrofina") +AnnotationAssertion(Annotation( "ChemIDplus") Annotation( ) "corticotrophine") +AnnotationAssertion(Annotation( "ChemIDplus") Annotation( ) "corticotrophinum") +AnnotationAssertion(Annotation( "ChemIDplus") Annotation( ) "corticotropin") +AnnotationAssertion(Annotation( "ChemIDplus") "cortrophin") +AnnotationAssertion( "CHEBI:3892") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "corticotropin") +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (indole alkaloid) + +AnnotationAssertion( "An alkaloid containing an indole skeleton.") +AnnotationAssertion( "CHEBI:24795") +AnnotationAssertion( "CHEBI:5901") +AnnotationAssertion( "KEGG:C06073") +AnnotationAssertion( "Wikipedia:Indole_alkaloid") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Indole alkaloid") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "indole alkaloids") +AnnotationAssertion( "CHEBI:38958") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "indole alkaloid") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (apolipoprotein) AnnotationAssertion( "Protein component on the surface of lipoprotein.") @@ -14528,6 +27161,20 @@ AnnotationAssertion(rdfs:label "Lew SubClassOf( ) SubClassOf( ) +# Class: (straight-chain saturated fatty acid) + +AnnotationAssertion( "Any saturated fatty acid lacking a side-chain.") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:15644336") +AnnotationAssertion(Annotation( "ChEBI") "straight-chain saturated fatty acid") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "straight-chain saturated fatty acids") +AnnotationAssertion( "CHEBI:39418") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "straight-chain saturated fatty acid") +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (dihydrogenphosphate) AnnotationAssertion( "A monovalent inorganic anion that consists of phosphoric acid in which one of the three OH groups has been deprotonated.") @@ -14560,6 +27207,48 @@ SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (cyclic ketone) + +AnnotationAssertion( "KEGG:C02019") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Cyclic ketone") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "cyclic ketones") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion( "CHEBI:3992") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "cyclic ketone") +SubClassOf( ) + +# Class: ((S)-adrenaline) + +AnnotationAssertion( "The S-enantiomer of adrenaline.") +AnnotationAssertion( "0") +AnnotationAssertion( "C9H13NO3") +AnnotationAssertion( "InChI=1S/C9H13NO3/c1-10-5-9(13)6-2-3-7(11)8(12)4-6/h2-4,9-13H,5H2,1H3/t9-/m1/s1") +AnnotationAssertion( "UCTWMZQNUQWSLP-SECBINFHSA-N") +AnnotationAssertion( "183.20446") +AnnotationAssertion( "183.08954") +AnnotationAssertion( "CNC[C@@H](O)c1ccc(O)c(O)c1") +AnnotationAssertion( "CHEBI:30615") +AnnotationAssertion( "CHEBI:40743") +AnnotationAssertion(Annotation( "ChemIDplus") "Beilstein:2938799") +AnnotationAssertion(Annotation( "ChemIDplus") "CAS:150-05-0") +AnnotationAssertion( "PDBeChem:ALE") +AnnotationAssertion(Annotation( "Reaxys") "Reaxys:2938799") +AnnotationAssertion(Annotation( "UniProt") "(S)-adrenaline") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "4-[(1S)-1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChemIDplus") "(+)-3,4-dihydroxy-alpha-((methylamino)methyl)benzyl alcohol") +AnnotationAssertion(Annotation( "IUPHAR") "(+)-adrenaline") +AnnotationAssertion(Annotation( "ChEBI") "(S)-(+)-adrenaline") +AnnotationAssertion(Annotation( "ChemIDplus") "(S)-4-(1-hydroxy-2-(methylamino)ethyl)pyrocatechol") +AnnotationAssertion(Annotation( "ChemIDplus") "d-adrenaline") +AnnotationAssertion(Annotation( "ChemIDplus") "d-epinephrine") +AnnotationAssertion( "CHEBI:40751") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "(S)-adrenaline") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (carbonate) AnnotationAssertion( "-2") @@ -14588,6 +27277,32 @@ AnnotationAssertion(rdfs:label "car SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (formyl group) + +AnnotationAssertion( "0") +AnnotationAssertion( "CHO") +AnnotationAssertion( "29.01804") +AnnotationAssertion( "29.00274") +AnnotationAssertion( "[H]C(*)=O") +AnnotationAssertion( "CHEBI:24089") +AnnotationAssertion( "CHEBI:42480") +AnnotationAssertion( "PDBeChem:FOR") +AnnotationAssertion(Annotation( "PDBeChem") "FORMYL GROUP") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "aldehyde group") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "carbaldehyde") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "formyl") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "IUPAC") "-CH(O)") +AnnotationAssertion(Annotation( "IUPAC") "-CHO") +AnnotationAssertion(Annotation( "CBN") "Fo") +AnnotationAssertion(Annotation( "IUPAC") "H-CO-") +AnnotationAssertion(Annotation( "IUPAC") "methanoyl") +AnnotationAssertion( "CHEBI:42485") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "formyl group") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (hydroxy group) AnnotationAssertion( "0") @@ -14649,6 +27364,32 @@ SubClassOf( ObjectSomeValuesFrom( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (ADP(3-)) + +AnnotationAssertion( "A nucleoside 5'-diphosphate(3-) arising from deprotonation of all three diphosphate OH groups of adenosine 5'-diphosphate (ADP); major species present at pH 7.3.") +AnnotationAssertion( "-3") +AnnotationAssertion( "C10H12N5O10P2") +AnnotationAssertion( "InChI=1S/C10H15N5O10P2/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(24-10)1-23-27(21,22)25-26(18,19)20/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H2,11,12,13)(H2,18,19,20)/p-3/t4-,6-,7-,10-/m1/s1") +AnnotationAssertion( "XTWYTFMLZFPYCI-KQYNXXCUSA-K") +AnnotationAssertion( "424.17730") +AnnotationAssertion( "424.00759") +AnnotationAssertion( "Nc1ncnc2n(cnc12)[C@@H]1O[C@H](COP([O-])(=O)OP([O-])([O-])=O)[C@@H](O)[C@H]1O") +AnnotationAssertion(Annotation( "Beilstein") "Beilstein:3783669") +AnnotationAssertion(Annotation( "Gmelin") "Gmelin:341336") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "adenosine 5'-diphosphate") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "5'-O-[(phosphonatooxy)phosphinato]adenosine") +AnnotationAssertion(Annotation( "UniProt") "ADP") +AnnotationAssertion(Annotation( "ChEBI") "ADP trianion") +AnnotationAssertion( "CHEBI:456216") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "ADP(3-)") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (hydrogensulfate) AnnotationAssertion( "-1") @@ -14767,6 +27508,146 @@ AnnotationAssertion( "carboxy group") SubClassOf( ) +# Class: (L-ribose) + +AnnotationAssertion( "A ribose in which the chiral carbon atom furthest away from the aldehyde group (C4') has the same configuration as in L-glyceraldehyde.") +AnnotationAssertion( "0") +AnnotationAssertion( "C5H10O5") +AnnotationAssertion( "150.130") +AnnotationAssertion( "150.05282") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "L-ribo-pentose") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "L-ribose") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "JCBN") "L-Rib") +AnnotationAssertion( "CHEBI:46997") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "L-ribose") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (ribofuranose) + +AnnotationAssertion( "A cyclic ribose having a 5-membered tetrahydrofuran ring; the predominant (C3'-endo) form of the two cyclic structures (the other is the \"C2'-endo\" form, having a 6-membered ring) adopted by ribose in aqueous solution.") +AnnotationAssertion( "0") +AnnotationAssertion( "C5H10O5") +AnnotationAssertion( "150.12990") +AnnotationAssertion( "150.05282") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "ribofuranose") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "IUPAC") "rel-(3R,4S,5R)-5-(hydroxymethyl)tetrahydrofuran-2,3,4-triol") +AnnotationAssertion( "CHEBI:46998") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "ribofuranose") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (D-ribofuranose) + +AnnotationAssertion( "A ribofuranose having D-configuration.") +AnnotationAssertion( "0") +AnnotationAssertion( "C5H10O5") +AnnotationAssertion( "InChI=1S/C5H10O5/c6-1-2-3(7)4(8)5(9)10-2/h2-9H,1H2/t2-,3-,4-,5?/m1/s1") +AnnotationAssertion( "HMFHBZSHGGEWLO-SOOFDHNKSA-N") +AnnotationAssertion( "150.12990") +AnnotationAssertion( "150.05282") +AnnotationAssertion( "OC[C@H]1OC(O)[C@H](O)[C@@H]1O") +AnnotationAssertion( "CHEBI:4233") +AnnotationAssertion( "CHEBI:46999") +AnnotationAssertion(Annotation( "Beilstein") "Beilstein:1904878") +AnnotationAssertion(Annotation( "KEGG COMPOUND") "CAS:50-69-1") +AnnotationAssertion(Annotation( "ChemIDplus") "CAS:613-83-2") +AnnotationAssertion( "GlyGen:G31080DL") +AnnotationAssertion( "GlyTouCan:G31080DL") +AnnotationAssertion(Annotation( "Gmelin") "Gmelin:364108") +AnnotationAssertion( "KEGG:C00121") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:9506998") +AnnotationAssertion( "Patent:US2152662") +AnnotationAssertion(Annotation( "Reaxys") "Reaxys:1904878") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "D-ribofuranose") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "IUPAC") "(3R,4S,5R)-5-(hydroxymethyl)tetrahydrofuran-2,3,4-triol") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "D-Ribose") +AnnotationAssertion(Annotation( "UniProt") "D-ribose") +AnnotationAssertion(Annotation( "GlyTouCan") "WURCS=2.0/1,1,0/[a222h-1x_1-4]/1/") +AnnotationAssertion(Annotation( "ChemIDplus") "ribose") +AnnotationAssertion( "CHEBI:47013") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "D-ribofuranose") +SubClassOf( ) +SubClassOf( ) + +# Class: (tetrahydrofuranol) + +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "tetrahydrofuranols") +AnnotationAssertion( "CHEBI:47017") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "tetrahydrofuranol") +SubClassOf( ) + +# Class: (dihydroxytetrahydrofuran) + +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "dihydroxytetrahydrofurans") +AnnotationAssertion( "CHEBI:47019") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "dihydroxytetrahydrofuran") +SubClassOf( ) + +# Class: (acetate ester) + +AnnotationAssertion( "Any carboxylic ester where the carboxylic acid component is acetic acid.") +AnnotationAssertion( "0") +AnnotationAssertion( "C2H3O2R") +AnnotationAssertion( "59.04400") +AnnotationAssertion( "59.01330") +AnnotationAssertion( "CC(=O)O[*]") +AnnotationAssertion( "CHEBI:13244") +AnnotationAssertion( "CHEBI:13799") +AnnotationAssertion( "CHEBI:22189") +AnnotationAssertion( "CHEBI:2406") +AnnotationAssertion( "KEGG:C01883") +AnnotationAssertion( "Wikipedia:Acetate#Esters") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Acetic ester") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Acetyl ester") +AnnotationAssertion(Annotation( "ChEBI") "acetate") +AnnotationAssertion(Annotation( "ChEBI") "acetate esters") +AnnotationAssertion(Annotation( "ChEBI") "acetates") +AnnotationAssertion(Annotation( "ChEBI") "acetyl esters") +AnnotationAssertion(Annotation( "UniProt") "an acetyl ester") +AnnotationAssertion( "CHEBI:47622") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "acetate ester") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (3-oxo steroid) + +AnnotationAssertion( "Any oxo steroid where an oxo substituent is located at position 3.") +AnnotationAssertion( "0") +AnnotationAssertion( "C19H29OR") +AnnotationAssertion( "273.434") +AnnotationAssertion( "273.22184") +AnnotationAssertion( "C12C(C3C(C(CC3)*)(C)CC1)CCC4C2(CCC(C4)=O)C") +AnnotationAssertion( "CHEBI:13607") +AnnotationAssertion( "CHEBI:1653") +AnnotationAssertion( "CHEBI:20182") +AnnotationAssertion( "CHEBI:71186") +AnnotationAssertion( "KEGG:C01876") +AnnotationAssertion( "MetaCyc:3-Oxosteroids") +AnnotationAssertion(Annotation( "SUBMITTER") "PMID:9811880") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "3-Oxosteroid") +AnnotationAssertion(Annotation( "ChEBI") "3-oxo steroids") +AnnotationAssertion(Annotation( "ChEBI") "3-oxosteroids") +AnnotationAssertion(Annotation( "UniProt") "a 3-oxosteroid") +AnnotationAssertion( "CHEBI:47788") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "3-oxo steroid") +SubClassOf( ) +SubClassOf( ) + # Class: (cyclic polypyrrole) AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "macrocyclic polypyrroles") @@ -14778,6 +27659,44 @@ AnnotationAssertion( "cyclic polypyrrole") SubClassOf( ) +# Class: (steroid acid) + +AnnotationAssertion( "Any steroid substituted by at least one carboxy group.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "steroid acids") +AnnotationAssertion( "CHEBI:47891") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "steroid acid") +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (3-oxo-Delta(4) steroid) + +AnnotationAssertion( "A 3-oxo steroid conjugated to a C=C double bond at the alpha,beta position.") +AnnotationAssertion( "0") +AnnotationAssertion( "C19H27OR") +AnnotationAssertion( "271.418") +AnnotationAssertion( "271.20619") +AnnotationAssertion( "C12C(C3C(C(CC3)*)(C)CC1)CCC=4C2(CCC(C4)=O)C") +AnnotationAssertion( "CHEBI:13604") +AnnotationAssertion( "CHEBI:1626") +AnnotationAssertion( "CHEBI:20157") +AnnotationAssertion( "KEGG:C00619") +AnnotationAssertion( "MetaCyc:3-Oxo-Delta-4-Steroids") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "3-Oxo-delta4-steroid") +AnnotationAssertion(Annotation( "ChEBI") "3-oxo Delta(4)-steroid") +AnnotationAssertion(Annotation( "ChEBI") "3-oxo Delta(4)-steroids") +AnnotationAssertion(Annotation( "ChEBI") "3-oxo-Delta(4) steroids") +AnnotationAssertion(Annotation( "UniProt") "a 3-oxo-Delta(4)-steroid") +AnnotationAssertion( "CHEBI:47909") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "3-oxo-Delta(4) steroid") +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (sulfur oxide) AnnotationAssertion( "chebi_ontology") @@ -14790,6 +27709,97 @@ AnnotationAssertion(rdfs:label "sul SubClassOf( ) SubClassOf( ) +# Class: (polar solvent) + +AnnotationAssertion( "A solvent that is composed of polar molecules. Polar solvents can dissolve ionic compounds or ionisable covalent compounds.") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "polar solvent") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "polar solvents") +AnnotationAssertion( "CHEBI:48354") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "polar solvent") +SubClassOf( ) + +# Class: (protic solvent) + +AnnotationAssertion( "A polar solvent that is capable of acting as a hydron (proton) donor.") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "protogenic solvent") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion( "CHEBI:48356") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "protic solvent") +SubClassOf( ) +SubClassOf( ) + +# Class: (protophilic solvent) + +AnnotationAssertion( "Solvent that is capable of acting as a hydron (proton) acceptor.") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "protophilic solvent") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "HBA solvent") +AnnotationAssertion(Annotation( "ChEBI") "hydrogen bond acceptor solvent") +AnnotationAssertion( "CHEBI:48359") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "protophilic solvent") +SubClassOf( ) +SubClassOf( ) + +# Class: (amphiprotic solvent) + +AnnotationAssertion( "Self-ionizing solvent possessing both characteristics of Bronsted acids and bases.") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "amphiprotic solvent") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion( "CHEBI:48360") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "amphiprotic solvent") +SubClassOf( ) +SubClassOf( ) + +# Class: (alpha-adrenergic drug) + +AnnotationAssertion( "Any drug that acts on an alpha-adrenergic receptor.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "alpha-adrenergic drugs") +AnnotationAssertion( "CHEBI:48539") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "alpha-adrenergic drug") +SubClassOf( ) + +# Class: (beta-adrenergic drug) + +AnnotationAssertion( "Any of the drugs that act on beta-adrenergic receptors.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "beta-adrenergic drugs") +AnnotationAssertion( "CHEBI:48540") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "beta-adrenergic drug") +SubClassOf( ) + +# Class: (dopaminergic agent) + +AnnotationAssertion( "A drug used for its effects on dopamine receptors, on the life cycle of dopamine, or on the survival of dopaminergic neurons.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "dopamine agent") +AnnotationAssertion(Annotation( "ChEBI") "dopamine agents") +AnnotationAssertion(Annotation( "ChEBI") "dopamine drug") +AnnotationAssertion(Annotation( "ChEBI") "dopamine drugs") +AnnotationAssertion(Annotation( "ChEBI") "dopaminergic agents") +AnnotationAssertion( "CHEBI:48560") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "dopaminergic agent") +SubClassOf( ) + +# Class: (radical scavenger) + +AnnotationAssertion( "A role played by a substance that can react readily with, and thereby eliminate, radicals.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "free radical scavengers") +AnnotationAssertion(Annotation( "ChEBI") "free-radical scavenger") +AnnotationAssertion( "CHEBI:48578") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "radical scavenger") +SubClassOf( ) + # Class: (agonist) AnnotationAssertion( "Substance which binds to cell receptors normally responding to naturally occurring substances and which produces a response of its own.") @@ -14816,6 +27826,17 @@ AnnotationAssertion( "antagonist") SubClassOf( ) +# Class: (contraceptive drug) + +AnnotationAssertion( "A chemical substance that prevents or reduces the probability of conception.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "contraceptive agent") +AnnotationAssertion(Annotation( "ChEBI") "contraceptive drugs") +AnnotationAssertion( "CHEBI:49323") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "contraceptive drug") +SubClassOf( ) + # Class: (hydrogen atom) AnnotationAssertion( "0") @@ -14857,6 +27878,49 @@ SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (sex hormone) + +AnnotationAssertion( "Any hormone that is responsible for controlling sexual characteristics and reproductive function.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "Geschlechtshormon") +AnnotationAssertion(Annotation( "ChEBI") "Geschlechtshormone") +AnnotationAssertion(Annotation( "ChEBI") "Sexualhormon") +AnnotationAssertion(Annotation( "ChEBI") "Sexualhormone") +AnnotationAssertion(Annotation( "ChEBI") "hormone sexuelle") +AnnotationAssertion(Annotation( "ChEBI") "hormones sexuelles") +AnnotationAssertion(Annotation( "ChEBI") "sex hormones") +AnnotationAssertion( "CHEBI:50112") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "sex hormone") +SubClassOf( ) + +# Class: (androgen) + +AnnotationAssertion( "A sex hormone that stimulates or controls the development and maintenance of masculine characteristics in vertebrates by binding to androgen receptors.") +AnnotationAssertion(Annotation( "ChEBI") "Androgen") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "Androgene") +AnnotationAssertion(Annotation( "ChEBI") "androgene") +AnnotationAssertion(Annotation( "ChEBI") "androgenes") +AnnotationAssertion(Annotation( "ChEBI") "androgeno") +AnnotationAssertion(Annotation( "ChEBI") "androgenos") +AnnotationAssertion(Annotation( "ChEBI") "androgens") +AnnotationAssertion( "CHEBI:50113") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "androgen") +SubClassOf( ) + +# Class: (steroid acid anion) + +AnnotationAssertion( "Any anion formed by loss of a proton from a steroid acid.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "steroid acid anions") +AnnotationAssertion( "CHEBI:50160") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "steroid acid anion") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (provitamin) AnnotationAssertion( "A substance that can be converted into a vitamin by animal tissues.") @@ -14868,6 +27932,47 @@ AnnotationAssertion( "provitamin") SubClassOf( ) +# Class: (protective agent) + +AnnotationAssertion( "Synthetic or natural substance which is given to prevent a disease or disorder or are used in the process of treating a disease or injury due to a poisonous agent.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "chemoprotectant") +AnnotationAssertion(Annotation( "ChEBI") "chemoprotectants") +AnnotationAssertion(Annotation( "ChEBI") "chemoprotective agent") +AnnotationAssertion(Annotation( "ChEBI") "chemoprotective agents") +AnnotationAssertion(Annotation( "ChEBI") "protective agents") +AnnotationAssertion( "CHEBI:50267") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "protective agent") +SubClassOf( ) + +# Class: (canonical nucleotide residue) + +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "canonical nucleotide residues") +AnnotationAssertion( "CHEBI:50297") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "canonical nucleotide residue") +SubClassOf( ) + +# Class: (canonical deoxyribonucleotide residue) + +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "canonical deoxyribonucleotide residues") +AnnotationAssertion( "CHEBI:50298") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "canonical deoxyribonucleotide residue") +SubClassOf( ) + +# Class: (canonical ribonucleotide residue) + +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "canonical ribonucleotide residues") +AnnotationAssertion( "CHEBI:50299") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "canonical ribonucleotide residue") +SubClassOf( ) + # Class: (onium compound) AnnotationAssertion( "chebi_ontology") @@ -14889,6 +27994,83 @@ AnnotationAssertion( "onium cation") SubClassOf( ) +# Class: (nucleotide residue) + +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "nucleotide residues") +AnnotationAssertion( "CHEBI:50319") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "nucleotide residue") +SubClassOf( ) + +# Class: (nucleoside residue) + +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "nucleoside residues") +AnnotationAssertion( "CHEBI:50320") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "nucleoside residue") +SubClassOf( ) + +# Class: (proteinogenic amino-acid side-chain group) + +AnnotationAssertion( "A univalent organyl group obtained by cleaving the bond from C-2 to the side chain of a proteinogenic amino-acid.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "canonical amino-acid side-chain") +AnnotationAssertion(Annotation( "ChEBI") "canonical amino-acid side-chains") +AnnotationAssertion(Annotation( "ChEBI") "proteinogenic amino-acid side-chain") +AnnotationAssertion(Annotation( "ChEBI") "proteinogenic amino-acid side-chain groups") +AnnotationAssertion(Annotation( "ChEBI") "proteinogenic amino-acid side-chains") +AnnotationAssertion( "CHEBI:50325") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "proteinogenic amino-acid side-chain group") +SubClassOf( ) + +# Class: (2-carboxyethyl group) + +AnnotationAssertion( "0") +AnnotationAssertion( "C3H5O2") +AnnotationAssertion( "73.07060") +AnnotationAssertion( "73.02895") +AnnotationAssertion( "C(CC(=O)O)*") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "2-carboxyethyl") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "glutamic acid side-chain") +AnnotationAssertion( "CHEBI:50329") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "2-carboxyethyl group") +SubClassOf( ) + +# Class: (androstanoid) + +AnnotationAssertion( "Any steroid based on an androstane skeleton and its derivatives.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "androstanoids") +AnnotationAssertion( "CHEBI:50402") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "androstanoid") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (mydriatic agent) + +AnnotationAssertion( "Agent that dilates the pupil. Used in eye diseases and to facilitate eye examination. It may be either a sympathomimetic or parasympatholytic. The latter cause cycloplegia or paralysis of accommodation at high doses and may precipitate glaucoma.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "mydriatics") +AnnotationAssertion( "CHEBI:50513") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "mydriatic agent") +SubClassOf( ) + +# Class: (vasoconstrictor agent) + +AnnotationAssertion( "Drug used to cause constriction of the blood vessels.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion( "CHEBI:50514") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "vasoconstrictor agent") +SubClassOf( ) + # Class: (bone density conservation agent) AnnotationAssertion( "An agent that inhibits bone resorption and/or favor bone mineralization and bone regeneration. Used to heal bone fractures and to treat bone diseases such as osteopenia and osteoporosis.") @@ -14919,6 +28101,87 @@ AnnotationAssertion( "bone density conservation agent") SubClassOf( ) +# Class: (reproductive control drug) + +AnnotationAssertion( "A substance used either in the prevention or facilitation of pregnancy.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "reproductive control agent") +AnnotationAssertion(Annotation( "ChEBI") "reproductive control drugs") +AnnotationAssertion( "CHEBI:50689") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "reproductive control drug") +SubClassOf( ) + +# Class: (nutraceutical) + +AnnotationAssertion( "A product in capsule, tablet or liquid form that provide essential nutrients, such as a vitamin, an essential mineral, a protein, an herb, or similar nutritional substance.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "Dietary Supplement") +AnnotationAssertion(Annotation( "ChEBI") "Food Supplementation") +AnnotationAssertion(Annotation( "ChEBI") "Nutritional supplement") +AnnotationAssertion( "CHEBI:50733") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "nutraceutical") +SubClassOf( ) + +# Class: (progestogen) + +AnnotationAssertion( "A compound that interacts with progesterone receptors in target tissues to bring about effects similar to those of progesterone.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "gestagen") +AnnotationAssertion(Annotation( "ChEBI") "gestagens") +AnnotationAssertion(Annotation( "ChEBI") "progestagen") +AnnotationAssertion(Annotation( "ChEBI") "progestagens") +AnnotationAssertion(Annotation( "ChEBI") "progestogens") +AnnotationAssertion( "CHEBI:50745") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "progestogen") +SubClassOf( ) + +# Class: (immunomodulator) + +AnnotationAssertion( "Biologically active substance whose activity affects or plays a role in the functioning of the immune system.") +AnnotationAssertion( "Wikipedia:Immunotherapy") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "Biomodulator") +AnnotationAssertion(Annotation( "ChEBI") "Immune factor") +AnnotationAssertion(Annotation( "ChEBI") "Immunologic factor") +AnnotationAssertion(Annotation( "ChEBI") "Immunological factor") +AnnotationAssertion(Annotation( "ChEBI") "immunomodulators") +AnnotationAssertion( "CHEBI:50846") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "immunomodulator") +SubClassOf( ) +SubClassOf( ) + +# Class: (immunological adjuvant) + +AnnotationAssertion( "A substance that augments, stimulates, activates, potentiates, or modulates the immune response at either the cellular or humoral level. A classical agent (Freund's adjuvant, BCG, Corynebacterium parvum, et al.) contains bacterial antigens. It could also be endogenous (e.g., histamine, interferon, transfer factor, tuftsin, interleukin-1). Its mode of action is either non-specific, resulting in increased immune responsiveness to a wide variety of antigens, or antigen-specific, i.e., affecting a restricted type of immune response to a narrow group of antigens. The therapeutic efficacy is related to its antigen-specific immunoadjuvanticity.") +AnnotationAssertion( "Wikipedia:Immunologic_adjuvant") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "Immunoactivator") +AnnotationAssertion(Annotation( "ChEBI") "Immunoadjuvant") +AnnotationAssertion(Annotation( "ChEBI") "Immunologic adjuvant") +AnnotationAssertion(Annotation( "ChEBI") "Immunopotentiator") +AnnotationAssertion(Annotation( "ChEBI") "Immunostimulant") +AnnotationAssertion( "CHEBI:50847") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "immunological adjuvant") +SubClassOf( ) +SubClassOf( ) + +# Class: (corticosteroid) + +AnnotationAssertion( "A natural or synthetic analogue of the hormones secreted by the adrenal gland.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "corticoides") +AnnotationAssertion(Annotation( "ChEBI") "corticosteroides") +AnnotationAssertion(Annotation( "ChEBI") "corticosteroids") +AnnotationAssertion( "CHEBI:50858") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "corticosteroid") +SubClassOf( ) + # Class: (organic molecular entity) AnnotationAssertion( "Any molecular entity that contains carbon.") @@ -14985,6 +28248,38 @@ AnnotationAssertion( "non-covalently-bound molecular entity") SubClassOf( ) +# Class: (primary amino compound) + +AnnotationAssertion( "A compound formally derived from ammonia by replacing one hydrogen atom by an organyl group.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "primary amino compounds") +AnnotationAssertion( "CHEBI:50994") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "primary amino compound") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (hormone agonist) + +AnnotationAssertion( "A chemical substance which binds to specific hormone receptors activating the function of the endocrine glands, the biosynthesis of their secreted hormones, or the action of hormones upon their specific sites.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion( "CHEBI:51060") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "hormone agonist") +SubClassOf( ) +SubClassOf( ) + +# Class: (hormone receptor modulator) + +AnnotationAssertion( "A drug that modulates the function of the endocrine glands, the biosynthesis of their secreted hormones, or the action of hormones upon their specific sites.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "hormone receptor modulators") +AnnotationAssertion( "CHEBI:51061") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "hormone receptor modulator") +SubClassOf( ) +SubClassOf( ) + # Class: (chemical role) AnnotationAssertion( "A role played by the molecular entity or part thereof within a chemical context.") @@ -15045,6 +28340,33 @@ AnnotationAssertion( "organic univalent group") SubClassOf( ) +# Class: (enone) + +AnnotationAssertion( "An alpha,beta-unsaturated ketone of general formula R(1)R(2)C=CR(3)-C(=O)R(4) (R(4) =/= H) in which the C=O function is conjugated to a C=C double bond at the alpha,beta position.") +AnnotationAssertion( "0") +AnnotationAssertion( "C3OR4") +AnnotationAssertion( "52.03150") +AnnotationAssertion( "51.99491") +AnnotationAssertion( "[*]\\C([*])=C(\\[*])C([*])=O") +AnnotationAssertion( "Wikipedia:Enone") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "enones") +AnnotationAssertion( "CHEBI:51689") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "enone") +SubClassOf( ) +SubClassOf( ) + +# Class: (alpha,beta-unsaturated ketone) + +AnnotationAssertion( "A ketone of general formula R(1)R(2)C=CR(3)-C(=O)R(4) (R(4) =/= H) or R(1)C#C-C(=O)R(2) (R(2) =/= H) in which the ketonic C=O function is conjugated to an unsaturated C-C bond at the alpha,beta position.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "alpha,beta-unsaturated ketones") +AnnotationAssertion( "CHEBI:51721") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "alpha,beta-unsaturated ketone") +SubClassOf( ) + # Class: (organic polycyclic compound) AnnotationAssertion( "chebi_ontology") @@ -15138,6 +28460,26 @@ AnnotationAssertion( "hydroxylapatite") SubClassOf( ) +# Class: (oxyketone) + +AnnotationAssertion( "A compound with the general formula R2C=O (R=/=H) where one or more of the R groups contains an oxy (-O-) group.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "oxyketones") +AnnotationAssertion( "CHEBI:52395") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "oxyketone") +SubClassOf( ) + +# Class: (alpha-oxyketone) + +AnnotationAssertion( "An oxyketone with the general formula R2C(=O) (R=/=H) where one or more of the R groups contains an oxy (-O-) group and the oxy and carbonyl groups are bonded to the same carbon atom.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "alpha-oxyketones") +AnnotationAssertion( "CHEBI:52396") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "alpha-oxyketone") +SubClassOf( ) + # Class: (galactolipid) AnnotationAssertion( "A glycolipid and which the glyco component is specified as galactosyl.") @@ -15147,6 +28489,26 @@ AnnotationAssertion( "galactolipid") SubClassOf( ) +# Class: (inorganic hydroxy compound) + +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "inorganic hydroxides") +AnnotationAssertion( "CHEBI:52625") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "inorganic hydroxy compound") +SubClassOf( ) +SubClassOf( ) + +# Class: (cyclic organic group) + +AnnotationAssertion( "An organic group that consists of a closed ring. It may be a substituent or a skeleton.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "cyclic organic groups") +AnnotationAssertion( "CHEBI:52845") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "cyclic organic group") +SubClassOf( ) + # Class: (epitope) AnnotationAssertion( "The biological role played by a material entity when bound by a receptor of the adaptive immune system. Specific site on an antigen to which an antibody binds.") @@ -15182,6 +28544,53 @@ AnnotationAssertion( "ionic macromolecule") SubClassOf( ) +# Class: (glucagon) + +AnnotationAssertion( "A 29-amino acid peptide hormone consisting of His, Ser, Gln, Gly, Thr, Phe, Thr, Ser, Asp, Tyr, Ser, Lys, Tyr, Leu, Asp, Ser, Arg, Arg, Ala, Gln, Asp, Phe, Val, Gln, Trp, Leu, Met, Asn and Thr residues joined in sequence.") +AnnotationAssertion( "0") +AnnotationAssertion( "C153H225N43O49S") +AnnotationAssertion( "InChI=1S/C153H225N43O49S/c1-72(2)52-97(133(226)176-96(47-51-246-11)132(225)184-104(60-115(159)209)143(236)196-123(78(10)203)151(244)245)179-137(230)103(58-83-64-167-89-29-19-18-28-87(83)89)183-131(224)95(43-46-114(158)208)177-148(241)120(74(5)6)194-141(234)101(54-79-24-14-12-15-25-79)182-138(231)105(61-117(211)212)185-130(223)94(42-45-113(157)207)171-124(217)75(7)170-127(220)91(31-22-49-165-152(160)161)172-128(221)92(32-23-50-166-153(162)163)174-146(239)110(69-199)191-140(233)107(63-119(215)216)186-134(227)98(53-73(3)4)178-135(228)99(56-81-33-37-85(204)38-34-81)180-129(222)90(30-20-21-48-154)173-145(238)109(68-198)190-136(229)100(57-82-35-39-86(205)40-36-82)181-139(232)106(62-118(213)214)187-147(240)111(70-200)192-150(243)122(77(9)202)195-142(235)102(55-80-26-16-13-17-27-80)188-149(242)121(76(8)201)193-116(210)66-168-126(219)93(41-44-112(156)206)175-144(237)108(67-197)189-125(218)88(155)59-84-65-164-71-169-84/h12-19,24-29,33-40,64-65,71-78,88,90-111,120-123,167,197-205H,20-23,30-32,41-63,66-70,154-155H2,1-11H3,(H2,156,206)(H2,157,207)(H2,158,208)(H2,159,209)(H,164,169)(H,168,219)(H,170,220)(H,171,217)(H,172,221)(H,173,238)(H,174,239)(H,175,237)(H,176,226)(H,177,241)(H,178,228)(H,179,230)(H,180,222)(H,181,232)(H,182,231)(H,183,224)(H,184,225)(H,185,223)(H,186,227)(H,187,240)(H,188,242)(H,189,218)(H,190,229)(H,191,233)(H,192,243)(H,193,210)(H,194,234)(H,195,235)(H,196,236)(H,211,212)(H,213,214)(H,215,216)(H,244,245)(H4,160,161,165)(H4,162,163,166)/t75-,76+,77+,78+,88-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,120-,121-,122-,123-/m0/s1") +AnnotationAssertion( "MASNOZXLGMXCHN-ZLPAWPGGSA-N") +AnnotationAssertion( "3482.74700") +AnnotationAssertion( "3480.61570") +AnnotationAssertion( "CSCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CO)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc1cnc[nH]1)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(O)=O") +AnnotationAssertion(Annotation( "ChemIDplus") "CAS:16941-32-5") +AnnotationAssertion(Annotation( "ChemIDplus") "CAS:9007-92-5") +AnnotationAssertion(Annotation( "KEGG COMPOUND") "CAS:9007-92-5") +AnnotationAssertion( "DrugBank:DB00040") +AnnotationAssertion(Annotation( "DrugCentral") "Drug_Central:2994") +AnnotationAssertion( "KEGG:C01501") +AnnotationAssertion( "KEGG:D00116") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:21940356") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:22014161") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:22154917") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:22166985") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:22167521") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:22214853") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:22227186") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:22286080") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:22294753") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:22318544") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:22334714") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:22399501") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:22438981") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:22454291") +AnnotationAssertion(Annotation( "Reaxys") "Reaxys:13191924") +AnnotationAssertion( "Wikipedia:Glucagon") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Glucagon") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "L-histidyl-L-seryl-L-glutaminylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-alpha-aspartyl-L-tyrosyl-L-seryl-L-lysyl-L-tyrosyl-L-leucyl-L-alpha-aspartyl-L-seryl-L-arginyl-L-arginyl-L-alanyl-L-glutaminyl-L-alpha-aspartyl-L-phenylalanyl-L-valyl-L-glutaminyl-L-tryptophyl-L-leucyl-L-methionyl-L-asparaginyl-L-threonine") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChemIDplus") "Glucagone") +AnnotationAssertion(Annotation( "ChEBI") "HSQGTFTSDYSKYLDSRRAQDFVQWLMNT") +AnnotationAssertion(Annotation( "ChEBI") "His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr") +AnnotationAssertion(Annotation( "ChemIDplus") "His-ser-glu(nh2)-gly-thr-phe-thr-ser-asp-tyr-ser-lys-tyr-leu-asp-ser-arg-arg-ala-glu(NH2)-asp-phe-val-glu(NH2)-trp-leu-met-asp(NH2)-thr") +AnnotationAssertion(Annotation( "ChemIDplus") Annotation( ) "glucagon") +AnnotationAssertion(Annotation( "ChemIDplus") Annotation( ) "glucagonum") +AnnotationAssertion( "CHEBI:5391") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "glucagon") +SubClassOf( ) + # Class: (heterocyclic compound) AnnotationAssertion( "A cyclic compound having as ring members atoms of at least two different elements.") @@ -15196,6 +28605,29 @@ AnnotationAssertion( "heterocyclic compound") SubClassOf( ) +# Class: (ATP(3-)) + +AnnotationAssertion( "A ribonucleoside triphosphate oxoanion that is the trianion of adenosine 5'-triphosphate arising from deprotonation of three of the four free triphosphate OH groups.") +AnnotationAssertion( "-3") +AnnotationAssertion( "C10H13N5O13P3") +AnnotationAssertion( "InChI=1S/C10H16N5O13P3/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20)/p-3/t4-,6-,7-,10-/m1/s1") +AnnotationAssertion( "ZKHQWZAMYRWXGA-KQYNXXCUSA-K") +AnnotationAssertion( "504.15720") +AnnotationAssertion( "503.97392") +AnnotationAssertion( "Nc1ncnc2n(cnc12)[C@@H]1O[C@H](COP([O-])(=O)OP([O-])(=O)OP(O)([O-])=O)[C@@H](O)[C@H]1O") +AnnotationAssertion(Annotation( "Beilstein") "Beilstein:9535056") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion( "CHEBI:57299") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "ATP(3-)") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (chondroitin D-glucuronate anion) AnnotationAssertion( "Anionic form of chondroitin D-glucuronate arising from deprotonation of the carboxylic acid groups of the repeating units; major species at pH 7.3.") @@ -15209,6 +28641,70 @@ AnnotationAssertion(rdfs:label "cho SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (nucleoside 5'-phosphate dianion) + +AnnotationAssertion( "The conjugate base of a nucleoside 5'-phosphate.") +AnnotationAssertion( "-2") +AnnotationAssertion( "C5H7O6PR2") +AnnotationAssertion( "194.07920") +AnnotationAssertion( "193.99802") +AnnotationAssertion( "O[C@H]1[C@@H]([*])[C@H]([*])O[C@@H]1COP([O-])([O-])=O") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "UniProt") "a nucleoside 5'-phosphate") +AnnotationAssertion(Annotation( "ChEBI") "nucleoside 5'-phosphate dianions") +AnnotationAssertion( "CHEBI:57867") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "nucleoside 5'-phosphate dianion") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (tryptaminium) + +AnnotationAssertion( "An ammonium ion that is the conjugate acid of tryptamine arising from protonation of the primary amino group; major species at pH 7.3.") +AnnotationAssertion( "+1") +AnnotationAssertion( "C10H13N2") +AnnotationAssertion( "InChI=1S/C10H12N2/c11-6-5-8-7-12-10-4-2-1-3-9(8)10/h1-4,7,12H,5-6,11H2/p+1") +AnnotationAssertion( "APJYDQYYACXCRM-UHFFFAOYSA-O") +AnnotationAssertion( "161.22310") +AnnotationAssertion( "161.10732") +AnnotationAssertion( "[NH3+]CCc1c[nH]c2ccccc12") +AnnotationAssertion(Annotation( "Gmelin") "Gmelin:533978") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "2-(1H-indol-3-yl)ethanaminium") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "UniProt") "tryptamine") +AnnotationAssertion(Annotation( "ChEBI") "tryptaminium cation") +AnnotationAssertion(Annotation( "ChEBI") "tryptaminium(1+)") +AnnotationAssertion( "CHEBI:57887") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "tryptaminium") +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (nucleoside 5'-diphosphate(3-)) + +AnnotationAssertion( "Trianion of nucleoside diphosphate arising from deprotonation of all three free OH groups of the diphosphate; major species at pH 7.3.") +AnnotationAssertion( "-3") +AnnotationAssertion( "C5H8O10P2R") +AnnotationAssertion( "290.059") +AnnotationAssertion( "289.95927") +AnnotationAssertion( "[C@H]1([C@H]([C@@H](O)[C@@H](O1)*)O)COP(OP([O-])(=O)[O-])(=O)[O-]") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "NDP trianion") +AnnotationAssertion(Annotation( "ChEBI") "NDP(3-)") +AnnotationAssertion(Annotation( "UniProt") "a ribonucleoside 5'-diphosphate") +AnnotationAssertion(Annotation( "ChEBI") "nucleoside diphosphate trianion") +AnnotationAssertion(Annotation( "ChEBI") "ribonucleoside diphosphate trianion") +AnnotationAssertion(Annotation( "ChEBI") "ribonucleoside diphosphate(3-)") +AnnotationAssertion( "CHEBI:57930") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "nucleoside 5'-diphosphate(3-)") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (bilirubin(2-)) AnnotationAssertion( "A dicarboxylic acid dianion obtained by deprotonation of the two carboxy groups of bilirubin; major species at pH 7.3.") @@ -15232,6 +28728,49 @@ SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (nucleoside 5'-triphoshate(3-)) + +AnnotationAssertion( "Trianion of nucleoside triphosphate arising from deprotonation of three of the four free triphosphate OH groups.") +AnnotationAssertion( "-3") +AnnotationAssertion( "C5H9O13P3R") +AnnotationAssertion( "370.039") +AnnotationAssertion( "369.92560") +AnnotationAssertion( "[C@H]1([C@H]([C@@H](O)[C@@H](O1)*)O)COP(OP(OP(=O)([O-])O)(=O)[O-])(=O)[O-]") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "NTP trianion") +AnnotationAssertion(Annotation( "ChEBI") "NTP(3-)") +AnnotationAssertion(Annotation( "ChEBI") "nucleoside triphosphate trianion") +AnnotationAssertion(Annotation( "ChEBI") "ribonucleoside triphosphate trianion") +AnnotationAssertion(Annotation( "ChEBI") "ribonucleoside triphosphate(3-)") +AnnotationAssertion( "CHEBI:58104") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "nucleoside 5'-triphoshate(3-)") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (histaminium) + +AnnotationAssertion( "An ammonium ion that is the conjugate acid of histamine protonated on the side-chain nitrogen.") +AnnotationAssertion( "+1") +AnnotationAssertion( "C5H10N3") +AnnotationAssertion( "InChI=1S/C5H9N3/c6-2-1-5-3-7-4-8-5/h3-4H,1-2,6H2,(H,7,8)/p+1") +AnnotationAssertion( "NTYJJOPFIAHURM-UHFFFAOYSA-O") +AnnotationAssertion( "112.15300") +AnnotationAssertion( "112.08692") +AnnotationAssertion( "[NH3+]CCc1c[nH]cn1") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "2-(1H-imidazol-4-yl)ethanaminium") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "UniProt") "histamine") +AnnotationAssertion(Annotation( "ChEBI") "histaminium cation") +AnnotationAssertion( "CHEBI:58432") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "histaminium") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (organophosphate oxoanion) AnnotationAssertion( "An organic phosphoric acid derivative in which one or more oxygen atoms of the phosphate group(s) has been deprotonated.") @@ -15243,6 +28782,44 @@ AnnotationAssertion(rdfs:label "org SubClassOf( ) SubClassOf( ) +# Class: (short-chain fatty acid anion) + +AnnotationAssertion( "Any fatty acid anion obtained by removal of a proton from the carboxy group of a short-chain fatty acid (chain length of less than C6).") +AnnotationAssertion( "-1") +AnnotationAssertion( "CO2R") +AnnotationAssertion( "44.010") +AnnotationAssertion( "43.98983") +AnnotationAssertion( "[O-]C([*])=O") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "UniProt") "a short-chain fatty acid") +AnnotationAssertion(Annotation( "ChEBI") "short-chain fatty acid anions") +AnnotationAssertion( "CHEBI:58951") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "short-chain fatty acid anion") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (saturated fatty acid anion) + +AnnotationAssertion( "Any fatty acid anion in which there is no C-C unsaturation.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "saturated fatty acid anions") +AnnotationAssertion( "CHEBI:58953") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "saturated fatty acid anion") +SubClassOf( ) + +# Class: (straight-chain saturated fatty acid anion) + +AnnotationAssertion( "Any saturated fatty acid anion lacking a carbon side-chain.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "straight-chain saturated fatty acid anions") +AnnotationAssertion( "CHEBI:58954") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "straight-chain saturated fatty acid anion") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (organosulfate oxoanion) AnnotationAssertion( "An organic anion of general formula RS(=O)2O(-) where R is an organyl group.") @@ -15261,6 +28838,30 @@ SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (straight-chain fatty acid) + +AnnotationAssertion( "Any fatty acid whose skeletal carbon atoms form an unbranched open chain.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "straight-chain fatty acids") +AnnotationAssertion( "CHEBI:59202") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "straight-chain fatty acid") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (straight-chain fatty acid anion) + +AnnotationAssertion( "A fatty acid anion formed by deprotonation of the carboxylic acid functional group of a straight-chain fatty acid.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "straight-chain FA anion") +AnnotationAssertion(Annotation( "ChEBI") "straight-chain FA anions") +AnnotationAssertion(Annotation( "ChEBI") "straight-chain fatty acid anions") +AnnotationAssertion( "CHEBI:59203") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "straight-chain fatty acid anion") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (linear tetrapyrrole anion) AnnotationAssertion( "An organic anion arising from deprotonation of a acyclic tetrapyrrole compound.") @@ -15282,6 +28883,18 @@ AnnotationAssertion( "phosphoric acids") SubClassOf( ) +# Class: (ribonucleoside triphosphate oxoanion) + +AnnotationAssertion( "An organophosphate anion resulting from deprotonation of at least one of the acidic hydroxy groups from the triphosphate moiety of a nucleoside triphosphate.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "ribonucleoside triphosphate anion") +AnnotationAssertion(Annotation( "ChEBI") "ribonucleoside triphosphate anions") +AnnotationAssertion(Annotation( "ChEBI") "ribonucleoside triphosphate oxoanions") +AnnotationAssertion( "CHEBI:59724") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "ribonucleoside triphosphate oxoanion") +SubClassOf( ) + # Class: (nucleophilic reagent) AnnotationAssertion( "A reagent that forms a bond to its reaction partner (the electrophile) by donating both bonding electrons.") @@ -15295,6 +28908,111 @@ AnnotationAssertion(rdfs:label "nuc SubClassOf( ) SubClassOf( ) +# Class: (L-alpha-amino acid anion) + +AnnotationAssertion( "Conjugate base of an L-alpha-amino acid arising from deprotonation of the C-1 carboxy group.") +AnnotationAssertion( "-1") +AnnotationAssertion( "C2H3NO2R") +AnnotationAssertion( "73.051") +AnnotationAssertion( "73.01638") +AnnotationAssertion( "[C@H](C(=O)[O-])(N)*") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "L-alpha-amino carboxylate") +AnnotationAssertion( "CHEBI:59814") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "L-alpha-amino acid anion") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (progestin) + +AnnotationAssertion( "A synthetic progestogen.") +AnnotationAssertion( "Wikipedia:Progestin") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "progestins") +AnnotationAssertion( "CHEBI:59826") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "progestin") +SubClassOf( ) + +# Class: (L-alpha-amino acid zwitterion) + +AnnotationAssertion( "Zwitterionic form of an L-alpha-amino acid having an anionic carboxy group and a protonated amino group.") +AnnotationAssertion( "0") +AnnotationAssertion( "C2H4NO2R") +AnnotationAssertion( "74.059") +AnnotationAssertion( "74.02420") +AnnotationAssertion( "[NH3+][C@@H]([*])C([O-])=O") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "L-alpha-amino acid zwitterions") +AnnotationAssertion(Annotation( "UniProt") "an L-alpha-amino acid") +AnnotationAssertion( "CHEBI:59869") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "L-alpha-amino acid zwitterion") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (D-alpha-amino acid zwitterion) + +AnnotationAssertion( "Zwitterionic form of a D-alpha-amino acid having an anionic carboxy group and a protonated amino group.") +AnnotationAssertion( "0") +AnnotationAssertion( "C2H4NO2R") +AnnotationAssertion( "74.059") +AnnotationAssertion( "74.02420") +AnnotationAssertion( "[NH3+][C@H]([*])C([O-])=O") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "D-alpha-amino acid zwitterions") +AnnotationAssertion(Annotation( "UniProt") "a D-alpha-amino acid") +AnnotationAssertion( "CHEBI:59871") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "D-alpha-amino acid zwitterion") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (gamma-aminobutyric acid zwitterion) + +AnnotationAssertion( "Zwitterionic form of gamma-aminobutyric acid having an anionic carboxy group and a protonated amino group.") +AnnotationAssertion( "0") +AnnotationAssertion( "C4H9NO2") +AnnotationAssertion( "InChI=1S/C4H9NO2/c5-3-1-2-4(6)7/h1-3,5H2,(H,6,7)") +AnnotationAssertion( "BTCSSZJGUNDROE-UHFFFAOYSA-N") +AnnotationAssertion( "103.11980") +AnnotationAssertion( "103.06333") +AnnotationAssertion( "[NH3+]CCCC([O-])=O") +AnnotationAssertion(Annotation( "Gmelin") "Gmelin:1041559") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "4-azaniumylbutanoate") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "UniProt") "4-aminobutanoate") +AnnotationAssertion(Annotation( "ChEBI") "4-ammoniobutanoate") +AnnotationAssertion( "CHEBI:59888") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "gamma-aminobutyric acid zwitterion") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (dopaminium(1+)) + +AnnotationAssertion( "An ammonium ion that is the conjugate acid of dopamine; major species at pH 7.3.") +AnnotationAssertion( "+1") +AnnotationAssertion( "C8H12NO2") +AnnotationAssertion( "InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2/p+1") +AnnotationAssertion( "VYFYYTLLBUKUHU-UHFFFAOYSA-O") +AnnotationAssertion( "154.18640") +AnnotationAssertion( "154.08626") +AnnotationAssertion( "[NH3+]CCc1ccc(O)c(O)c1") +AnnotationAssertion(Annotation( "Gmelin") "Gmelin:328863") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "2-(3,4-dihydroxyphenyl)ethanaminium") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "2-(3,4-dihydroxyphenyl)ethan-1-aminium") +AnnotationAssertion(Annotation( "UniProt") "dopamine") +AnnotationAssertion(Annotation( "ChEBI") "dopaminium cation") +AnnotationAssertion( "CHEBI:59905") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "dopaminium(1+)") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (chemical substance) AnnotationAssertion( "A chemical substance is a portion of matter of constant composition, composed of molecular entities of the same type or of different types.") @@ -15374,6 +29092,45 @@ AnnotationAssertion(rdfs:label "pep SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (adjuvant) + +AnnotationAssertion( "Any pharmacological or immunological agent that modifies the effect of other agents such as drugs or vaccines while having few if any direct effects when given by itself.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "adjuvants") +AnnotationAssertion( "CHEBI:60809") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "adjuvant") +SubClassOf( ) + +# Class: (D-alpha-amino acid anion) + +AnnotationAssertion( "Any alpha-amino acid anion in which the parent amino acid has D-configuration.") +AnnotationAssertion( "-1") +AnnotationAssertion( "C2H3NO2R") +AnnotationAssertion( "73.051") +AnnotationAssertion( "73.01638") +AnnotationAssertion( "[C@@H](C(=O)[O-])(N)*") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "D-alpha-amino acid anions") +AnnotationAssertion(Annotation( "ChEBI") "D-alpha-amino carboxylate") +AnnotationAssertion( "CHEBI:60895") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "D-alpha-amino acid anion") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (racemate) + +AnnotationAssertion( "A racemate is an equimolar mixture of a pair of enantiomers.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "melange racemique") +AnnotationAssertion(Annotation( "ChEBI") "racemates") +AnnotationAssertion(Annotation( "ChEBI") "racemic mixture") +AnnotationAssertion( "CHEBI:60911") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "racemate") +SubClassOf( ) + # Class: (keratan sulfate) AnnotationAssertion( "A sulfated glycosaminoglycan, a linear polymer that consists of the repeating disaccharide [3)-beta-Gal-(1->4)-beta-GlcNAc-(1->] and containing sulfo groups located at random positions.") @@ -15397,6 +29154,83 @@ AnnotationAssertion( "amino monosaccharide") SubClassOf( ) +# Class: (EC 3.5.1.98 (histone deacetylase) inhibitor) + +AnnotationAssertion( "An EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the function of histone deacetylase (EC 3.5.1.98).") +AnnotationAssertion( "Wikipedia:Histone_deacetylase_inhibitor") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "EC 3.5.1.98 (histone deacetylase) inhibitors") +AnnotationAssertion(Annotation( "ChEBI") "EC 3.5.1.98 inhibitor") +AnnotationAssertion(Annotation( "ChEBI") "EC 3.5.1.98 inhibitors") +AnnotationAssertion(Annotation( "ChEBI") "HDAC inhibitor") +AnnotationAssertion(Annotation( "ChEBI") "HDAC inhibitors") +AnnotationAssertion(Annotation( "ChEBI") "HDACi") +AnnotationAssertion(Annotation( "ChEBI") "HDACis") +AnnotationAssertion(Annotation( "ChEBI") "HDI") +AnnotationAssertion(Annotation( "ChEBI") "HDIs") +AnnotationAssertion(Annotation( "ChEBI") "histone amidohydrolase inhibitor") +AnnotationAssertion(Annotation( "ChEBI") "histone amidohydrolase inhibitors") +AnnotationAssertion(Annotation( "ChEBI") "histone deacetylase (EC 3.5.1.98) inhibitor") +AnnotationAssertion(Annotation( "ChEBI") "histone deacetylase (EC 3.5.1.98) inhibitors") +AnnotationAssertion(Annotation( "ChEBI") "histone deacetylase inhibitor") +AnnotationAssertion(Annotation( "ChEBI") "histone deacetylase inhibitors") +AnnotationAssertion( "CHEBI:61115") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "EC 3.5.1.98 (histone deacetylase) inhibitor") +SubClassOf( ) + +# Class: (nucleobase-containing molecular entity) + +AnnotationAssertion( "Any compound that has a nucleobase as a part.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "SUBMITTER") "nucleobase-containing compound") +AnnotationAssertion(Annotation( "ChEBI") "nucleobase-containing compounds") +AnnotationAssertion(Annotation( "ChEBI") "nucleobase-containing molecular entities") +AnnotationAssertion( "CHEBI:61120") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "nucleobase-containing molecular entity") +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (adenyl nucleotide) + +AnnotationAssertion( "A nucleotide having adenine as the base.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "SUBMITTER") "adenine nucleotide") +AnnotationAssertion( "CHEBI:61293") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "adenyl nucleotide") +SubClassOf( ) + +# Class: (adenyl ribonucleotide) + +AnnotationAssertion( "A purine riboncleotide where adenine is the purine.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "SUBMITTER") "adenine ribonucleotide") +AnnotationAssertion( "CHEBI:61296") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "adenyl ribonucleotide") +SubClassOf( ) +SubClassOf( ) + +# Class: (C21-steroid) + +AnnotationAssertion( "A steroid that has a structure based on a 21-carbon (pregnane) skeleton. Note that individual examples may have ring substituents at other positions and/or contain double bonds, aromatic A-rings, expanded/contracted rings etc., so the formula and mass may vary from that given for the generic structure.") +AnnotationAssertion( "0") +AnnotationAssertion( "C21H36") +AnnotationAssertion( "InChI=1S/C21H36/c1-4-15-9-11-18-17-10-8-16-7-5-6-13-20(16,2)19(17)12-14-21(15,18)3/h15-19H,4-14H2,1-3H3") +AnnotationAssertion( "JWMFYGXQPXQEEM-UHFFFAOYSA-N") +AnnotationAssertion( "288.511") +AnnotationAssertion( "288.28170") +AnnotationAssertion( "C1CCCC2C1(C3C(CC2)C4C(CC3)(C(CC4)CC)C)C") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "UniProt") "a C21-steroid") +AnnotationAssertion( "CHEBI:61313") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "C21-steroid") +SubClassOf( ) + # Class: (polyanionic polymer) AnnotationAssertion( "A polymer, composed of polyanion macromolecules.") @@ -15409,6 +29243,57 @@ AnnotationAssertion(rdfs:label "pol SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (nucleoside 5'-triphoshate(4-)) + +AnnotationAssertion( "A ribonucleoside triphosphate oxoanion arising from global deprotonation of the triphosphate groups of any nucleoside triphosphate; major species at pH 7.3.") +AnnotationAssertion( "-4") +AnnotationAssertion( "C5H8O13P3R") +AnnotationAssertion( "369.031") +AnnotationAssertion( "368.91778") +AnnotationAssertion( "[C@H]1([C@H]([C@@H](O)[C@@H](O1)*)O)COP(OP(OP(=O)([O-])[O-])(=O)[O-])(=O)[O-]") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "NTP tetraanion") +AnnotationAssertion(Annotation( "SUBMITTER") "NTP(4-)") +AnnotationAssertion(Annotation( "UniProt") "a ribonucleoside 5'-triphosphate") +AnnotationAssertion(Annotation( "ChEBI") "nucleoside 5'-triphosphate tetraanion") +AnnotationAssertion(Annotation( "ChEBI") "nucleoside triphosphate(4-)") +AnnotationAssertion( "CHEBI:61557") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "nucleoside 5'-triphoshate(4-)") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (polar amino acid zwitterion) + +AnnotationAssertion( "Zwitterionic form of a polar amino acid having an anionic carboxy group and a protonated amino group.") +AnnotationAssertion( "0") +AnnotationAssertion( "C2H4NO2R") +AnnotationAssertion( "74.059") +AnnotationAssertion( "74.02420") +AnnotationAssertion( "C(C([O-])=O)(*)[NH3+]") +AnnotationAssertion(Annotation( "SUBMITTER") "MetaCyc:Polar-amino-acids") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "UniProt") "a polar amino acid") +AnnotationAssertion( "CHEBI:62031") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "polar amino acid zwitterion") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (signalling molecule) + +AnnotationAssertion( "A molecular messenger in which the molecule is specifically involved in transmitting information between cells. Such molecules are released from the cell sending the signal, cross over the gap between cells by diffusion, and interact with specific receptors in another cell, triggering a response in that cell by activating a series of enzyme controlled reactions which lead to changes inside the cell.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "signal molecule") +AnnotationAssertion(Annotation( "ChEBI") "signal molecules") +AnnotationAssertion(Annotation( "ChEBI") "signaling molecule") +AnnotationAssertion(Annotation( "ChEBI") "signaling molecules") +AnnotationAssertion(Annotation( "ChEBI") "signalling molecules") +AnnotationAssertion( "CHEBI:62488") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "signalling molecule") +SubClassOf( ) + # Class: (anionic phospholipid) AnnotationAssertion( "Any organophosphate oxoanion that is a negatively charged phospholipid, e.g. phosphatidylserine(1-), phosphatidate(2-), phosphatidylglycerol(1-).") @@ -15433,6 +29318,34 @@ AnnotationAssertion(rdfs:label "gly SubClassOf( ) SubClassOf( ) +# Class: (glycosyl compound) + +AnnotationAssertion( "A carbohydrate derivative arising formally from the elimination of water from a glycosidic hydroxy group and an H atom bound to an oxygen, carbon, nitrogen or sulfur atom of a separate entity.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "glycosyl compounds") +AnnotationAssertion( "CHEBI:63161") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "glycosyl compound") +SubClassOf( ) + +# Class: (oxidising agent) + +AnnotationAssertion( "A substance that removes electrons from another reactant in a redox reaction.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "oxidant") +AnnotationAssertion(Annotation( "ChEBI") "oxidants") +AnnotationAssertion(Annotation( "ChEBI") "oxidiser") +AnnotationAssertion(Annotation( "ChEBI") "oxidisers") +AnnotationAssertion(Annotation( "ChEBI") "oxidising agents") +AnnotationAssertion(Annotation( "ChEBI") "oxidizer") +AnnotationAssertion(Annotation( "ChEBI") "oxidizers") +AnnotationAssertion(Annotation( "ChEBI") "oxidizing agent") +AnnotationAssertion(Annotation( "ChEBI") "oxidizing agents") +AnnotationAssertion( "CHEBI:63248") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "oxidising agent") +SubClassOf( ) + # Class: (carbohydrate derivative) AnnotationAssertion( "Any organooxygen compound derived from a carbohydrate by replacement of one or more hydroxy group(s) by an amino group, a thiol group or similar heteroatomic groups. The term also includes derivatives of these compounds.") @@ -15448,6 +29361,28 @@ AnnotationAssertion(rdfs:label "car SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (monosaccharide derivative) + +AnnotationAssertion( "A carbohydrate derivative that is formally obtained from a monosaccharide.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "monosaccharide derivatives") +AnnotationAssertion( "CHEBI:63367") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "monosaccharide derivative") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (pentose derivative) + +AnnotationAssertion( "A monosaccharide derivative that is formally obtained from a pentose.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "pentose derivatives") +AnnotationAssertion( "CHEBI:63409") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "pentose derivative") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (carbohydrate acid derivative) AnnotationAssertion( "A carbohydrate derivative that is formally obtained from a carbohydrate acid.") @@ -15460,6 +29395,27 @@ SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (monoamine) + +AnnotationAssertion( "An aralylamino compound which contains one amino group connected to an aromatic ring by a two-carbon chain. Monoamines are derived from aromatic amino acids like phenylalanine, tyrosine, tryptophan, and the thyroid hormones by the action of aromatic amino acid decarboxylase enzymes.") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:21822758") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:21993877") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:22005599") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:22082101") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:22153577") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:22213370") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:22218931") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:22342987") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:22371656") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "monoamines") +AnnotationAssertion(Annotation( "ChEBI") "naturally occurring monoamine") +AnnotationAssertion(Annotation( "ChEBI") "naturally occurring monoamines") +AnnotationAssertion( "CHEBI:63534") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "monoamine") +SubClassOf( ) + # Class: (carbohydrate acid derivative anion) AnnotationAssertion( "A carboxylic acid anion resulting from the deprotonation of the carboxy group of a carbohydrate acid derivative.") @@ -15486,6 +29442,31 @@ AnnotationAssertion(rdfs:label "foo SubClassOf( ) SubClassOf( ) +# Class: (food acidity regulator) + +AnnotationAssertion( "A food additive that is used to change or otherwise control the acidity or alkalinity of foods. They may be acids, bases, neutralising agents or buffering agents.") +AnnotationAssertion( "Wikipedia:Acidity_regulator") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "acidity regulator") +AnnotationAssertion(Annotation( "ChEBI") "acidity regulators") +AnnotationAssertion(Annotation( "ChEBI") "food acidity regulators") +AnnotationAssertion(Annotation( "ChEBI") "pH control agent") +AnnotationAssertion(Annotation( "ChEBI") "pH control agents") +AnnotationAssertion( "CHEBI:64049") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "food acidity regulator") +SubClassOf( ) + +# Class: (aralkylamino compound) + +AnnotationAssertion( "An organic amino compound in which an aminoalkyl group is linked to an arene.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "aralkylamino compounds") +AnnotationAssertion( "CHEBI:64365") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "aralkylamino compound") +SubClassOf( ) + # Class: (sphingomyelin) AnnotationAssertion( "Any of a class of phospholipids in which the amino group of a sphingoid base is in amide linkage with one of several fatty acids, while the terminal hydroxy group of the sphingoid base is esterified to phosphorylcholine.") @@ -15507,6 +29488,59 @@ SubClassOf( ) SubClassOf( ) +# Class: (C21-steroid hormone) + +AnnotationAssertion( "A steroid compound with a structure based on a 21-carbon (pregnane) skeleton that acts as a hormone.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "C21-steroid hormones") +AnnotationAssertion( "CHEBI:64600") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "C21-steroid hormone") +SubClassOf( ) +SubClassOf( ) + +# Class: (somatostatin) + +AnnotationAssertion( "A fourteen-membered heterodetic cyclic peptide comprising the sequence Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys cyclised by a disulfide bridge between the two Cys residues at positions 3 and 14.") +AnnotationAssertion( "0") +AnnotationAssertion( "C76H104N18O19S2") +AnnotationAssertion( "InChI=1S/C76H104N18O19S2/c1-41(79)64(100)82-37-61(99)83-58-39-114-115-40-59(76(112)113)92-72(108)57(38-95)91-75(111)63(43(3)97)94-71(107)54(33-46-23-11-6-12-24-46)90-74(110)62(42(2)96)93-66(102)51(28-16-18-30-78)84-69(105)55(34-47-36-81-49-26-14-13-25-48(47)49)88-68(104)53(32-45-21-9-5-10-22-45)86-67(103)52(31-44-19-7-4-8-20-44)87-70(106)56(35-60(80)98)89-65(101)50(85-73(58)109)27-15-17-29-77/h4-14,19-26,36,41-43,50-59,62-63,81,95-97H,15-18,27-35,37-40,77-79H2,1-3H3,(H2,80,98)(H,82,100)(H,83,99)(H,84,105)(H,85,109)(H,86,103)(H,87,106)(H,88,104)(H,89,101)(H,90,110)(H,91,111)(H,92,108)(H,93,102)(H,94,107)(H,112,113)/t41-,42+,43+,50-,51-,52-,53-,54-,55-,56-,57-,58-,59-,62-,63-/m0/s1") +AnnotationAssertion( "NHXLMOGPVYXJNR-ATOGVRKGSA-N") +AnnotationAssertion( "1637.87800") +AnnotationAssertion( "1636.71666") +AnnotationAssertion( "C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC1=O)[C@@H](C)O)C(O)=O)NC(=O)CNC(=O)[C@H](C)N") +AnnotationAssertion(Annotation( "ChemIDplus") "CAS:38916-34-6") +AnnotationAssertion(Annotation( "KEGG DRUG") "CAS:38916-34-6") +AnnotationAssertion(Annotation( "DrugCentral") "Drug_Central:2997") +AnnotationAssertion( "HMDB:HMDB0013072") +AnnotationAssertion( "KEGG:C16022") +AnnotationAssertion( "KEGG:D07431") +AnnotationAssertion( "LINCS:LSM-5326") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:21922516") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:22129035") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:22147011") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:22251942") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:22483686") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:22509294") +AnnotationAssertion(Annotation( "Reaxys") "Reaxys:10148626") +AnnotationAssertion( "Wikipedia:Somatostatin") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "L-alanyl-N-[(4R,7S,10S,13S,16S,19S,22S,25S,28S,31S,34S,37R)-19,34-bis(4-aminobutyl)-31-(2-amino-2-oxoethyl)-13,25,28-tribenzyl-4-carboxy-10,16-bis[(1R)-1-hydroxyethyl]-7-(hydroxymethyl)-22-(1H-indol-3-ylmethyl)-6,9,12,15,18,21,24,27,30,33,36-undecaoxo-1,2-dithia-5,8,11,14,17,20,23,26,29,32,35-undecaazacyclooctatriacontan-37-yl]glycinamide") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "Ala-Gly-cyclo-[Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys]") +AnnotationAssertion(Annotation( "ChemIDplus") "L-alanylglycyl-L-cysteinyl-L-lysyl-L-asparaginyl-L-phenylalanyl-L-phenylalanyl-L-tryptophyl-L-lysyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-cysteine cyclic (3-14) disulfide") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Somatostatin-1") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Somatostatin-14") +AnnotationAssertion(Annotation( "ChemIDplus") "Synthetic growth hormone release-inhibiting hormone") +AnnotationAssertion(Annotation( "KEGG_DRUG") Annotation( ) "somatostatin") +AnnotationAssertion(Annotation( "ChemIDplus") Annotation( ) "somatostatina") +AnnotationAssertion(Annotation( "ChemIDplus") Annotation( ) "somatostatine") +AnnotationAssertion(Annotation( "ChemIDplus") Annotation( ) "somatostatinum") +AnnotationAssertion( "CHEBI:64628") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "somatostatin") +SubClassOf( ) +SubClassOf( ) + # Class: (divalent inorganic cation) AnnotationAssertion( "An inorganic cation with a valency of two.") @@ -15584,6 +29618,29 @@ SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (food preservative) + +AnnotationAssertion( "Substances which are added to food in order to prevent decomposition caused by microbial growth or by undesirable chemical changes.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "food preservatives") +AnnotationAssertion( "CHEBI:65255") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "food preservative") +SubClassOf( ) + +# Class: (antimicrobial food preservative) + +AnnotationAssertion( "A food preservative which prevents decomposition of food by preventing the growth of fungi or bacteria. In European countries, E-numbers for permitted food preservatives are from E200 to E299, divided into sorbates (E200-209), benzoates (E210-219), sulfites (E220-229), phenols and formates (E230-239), nitrates (E240-259), acetates (E260-269), lactates (E270-279), propionates (E280-289) and others (E290-299).") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "antimicrobial food preservatives") +AnnotationAssertion(Annotation( "ChEBI") "antimicrobial preservative") +AnnotationAssertion(Annotation( "ChEBI") "antimicrobial preservatives") +AnnotationAssertion( "CHEBI:65256") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "antimicrobial food preservative") +SubClassOf( ) +SubClassOf( ) + # Class: (antacid) AnnotationAssertion( "Any substance which is used to neutralise stomach acidity.") @@ -15596,6 +29653,36 @@ AnnotationAssertion(rdfs:label "ant SubClassOf( ) SubClassOf( ) +# Class: (primary ammonium ion) + +AnnotationAssertion( "An ammonium ion derivative resulting from the protonation of the nitrogen atom of a primary amino compound. Major species at pH 7.3.") +AnnotationAssertion( "+1") +AnnotationAssertion( "H3NR") +AnnotationAssertion( "17.031") +AnnotationAssertion( "17.02655") +AnnotationAssertion( "[NH3+][*]") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "UniProt") "a primary amine") +AnnotationAssertion(Annotation( "ChEBI") "substituted ammonium") +AnnotationAssertion( "CHEBI:65296") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "primary ammonium ion") +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (anti-inflammatory agent) + +AnnotationAssertion( "Any compound that has anti-inflammatory effects.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "anti-inflammatory agents") +AnnotationAssertion(Annotation( "ChEBI") "antiinflammatory agent") +AnnotationAssertion(Annotation( "ChEBI") "antiinflammatory agents") +AnnotationAssertion( "CHEBI:67079") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "anti-inflammatory agent") +SubClassOf( ) + # Class: (provitamin A) AnnotationAssertion( "A provitamin that can be converted into vitamin A by enzymes from animal tissues.") @@ -15606,6 +29693,92 @@ AnnotationAssertion( "provitamin A") SubClassOf( ) +# Class: (azole) + +AnnotationAssertion( "Any monocyclic heteroarene consisting of a five-membered ring containing nitrogen. Azoles can also contain one or more other non-carbon atoms, such as nitrogen, sulfur or oxygen.") +AnnotationAssertion( "Wikipedia:Azole") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "azoles") +AnnotationAssertion( "CHEBI:68452") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "azole") +SubClassOf( ) +SubClassOf( ) + +# Class: (progesterone receptor agonist) + +AnnotationAssertion( "A hormone agonist that binds to and activates progesterone receptors.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "PR agonist") +AnnotationAssertion(Annotation( "ChEBI") "PR agonists") +AnnotationAssertion(Annotation( "ChEBI") "progesterone receptor agonists") +AnnotationAssertion( "CHEBI:70709") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "progesterone receptor agonist") +SubClassOf( ) + +# Class: ((R)-adrenaline(1+)) + +AnnotationAssertion( "An organic cation that is the conjugate acid of (R)-adrenaline, obtained by protonation of the amino group; major species at pH 7.3.") +AnnotationAssertion( "+1") +AnnotationAssertion( "C9H14NO3") +AnnotationAssertion( "InChI=1S/C9H13NO3/c1-10-5-9(13)6-2-3-7(11)8(12)4-6/h2-4,9-13H,5H2,1H3/p+1/t9-/m0/s1") +AnnotationAssertion( "UCTWMZQNUQWSLP-VIFPVBQESA-O") +AnnotationAssertion( "184.21240") +AnnotationAssertion( "184.09682") +AnnotationAssertion( "C[NH2+]C[C@H](O)c1ccc(O)c(O)c1") +AnnotationAssertion( "MetaCyc:L-EPINEPHRINE") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "(2R)-2-(3,4-dihydroxyphenyl)-2-hydroxy-N-methylethanaminium") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "UniProt") "(R)-adrenaline") +AnnotationAssertion(Annotation( "ChEBI") "(R)-adrenaline cation") +AnnotationAssertion(Annotation( "ChEBI") "L-epinephrine cation") +AnnotationAssertion(Annotation( "ChEBI") "L-epinephrine(1+)") +AnnotationAssertion( "CHEBI:71406") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "(R)-adrenaline(1+)") +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (gamma-amino acid anion) + +AnnotationAssertion( "An amino-acid anion in which the amino group is situated gamma- to the carboxylate group.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "gamma-amino acid anions") +AnnotationAssertion( "CHEBI:71666") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "gamma-amino acid anion") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: ((R)-noradrenaline(1+)) + +AnnotationAssertion( "An organic cation that is the conjugate acid of (R)-noradrenaline, obtained by protonation of the priamry amino group; major species at pH 7.3.") +AnnotationAssertion( "+1") +AnnotationAssertion( "C8H12NO3") +AnnotationAssertion( "InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2/p+1/t8-/m0/s1") +AnnotationAssertion( "SFLSHLFXELFNJZ-QMMMGPOBSA-O") +AnnotationAssertion( "170.187") +AnnotationAssertion( "170.08117") +AnnotationAssertion( "C=1(C=CC(=CC1O)[C@H](C[NH3+])O)O") +AnnotationAssertion( "PDBeChem:E5E") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "(2R)-2-(3,4-dihydroxyphenyl)-2-hydroxyethanaminium") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "UniProt") "(R)-noradrenaline") +AnnotationAssertion(Annotation( "ChEBI") "(R)-noradrenaline cation") +AnnotationAssertion(Annotation( "ChEBI") "(R)-noradrenalinium cation") +AnnotationAssertion(Annotation( "ChEBI") "(R)-noradrenalinium(1+)") +AnnotationAssertion( "CHEBI:72587") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "(R)-noradrenaline(1+)") +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (organic molecule) AnnotationAssertion( "Any molecule that consists of at least one carbon atom as part of the electrically neutral entity.") @@ -15662,6 +29835,80 @@ AnnotationAssertion( "vulnerary") SubClassOf( ) +# Class: (indole skeleton) + +AnnotationAssertion( "A mancude heterobicyclic organic group consisting of a benzene ring fused to a pyrrole ring.") +AnnotationAssertion( "0") +AnnotationAssertion( "C8N") +AnnotationAssertion( "110.09230") +AnnotationAssertion( "110.00307") +AnnotationAssertion( "C1(=C(C(=C2C(=C1*)N(C(=C2*)*)*)*)*)*") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion( "CHEBI:73398") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "indole skeleton") +SubClassOf( ) + +# Class: (organic heterobicyclic ring) + +AnnotationAssertion( "A bicyclic organic group that contains both carbon and hetero atoms.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "organic heterobicyclic rings") +AnnotationAssertion( "CHEBI:73541") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "organic heterobicyclic ring") +SubClassOf( ) + +# Class: (astringent) + +AnnotationAssertion( "A compound that causes the contraction of body tissues, typically used to reduce bleeding from minor abrasions.") +AnnotationAssertion( "Wikipedia:Astringent") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "adstringent") +AnnotationAssertion(Annotation( "ChEBI") "adstringents") +AnnotationAssertion(Annotation( "ChEBI") "astringents") +AnnotationAssertion( "CHEBI:74783") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "astringent") +SubClassOf( ) + +# Class: (EC 6.3.* (C-N bond-forming ligase) inhibitor) + +AnnotationAssertion( "A ligase inhibitor that interferes with the action of a C-N bond-forming ligase (EC 6.3.*.*).") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "C--N bond-forming ligase inhibitor") +AnnotationAssertion(Annotation( "ChEBI") "C--N bond-forming ligase inhibitors") +AnnotationAssertion(Annotation( "ChEBI") "C-N bond-forming ligase (EC 6.3.*) inhibitor") +AnnotationAssertion(Annotation( "ChEBI") "C-N bond-forming ligase (EC 6.3.*) inhibitors") +AnnotationAssertion(Annotation( "ChEBI") "C-N bond-forming ligase inhibitor") +AnnotationAssertion(Annotation( "ChEBI") "C-N bond-forming ligase inhibitors") +AnnotationAssertion(Annotation( "ChEBI") "EC 6.3.* (C-N bond-forming ligase) inhibitorS") +AnnotationAssertion(Annotation( "ChEBI") "EC 6.3.* inhibitor") +AnnotationAssertion(Annotation( "ChEBI") "EC 6.3.* inhibitors") +AnnotationAssertion(Annotation( "ChEBI") "EC 6.3.*.* inhibitor") +AnnotationAssertion(Annotation( "ChEBI") "EC 6.3.*.* inhibitors") +AnnotationAssertion( "CHEBI:75600") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "EC 6.3.* (C-N bond-forming ligase) inhibitor") +SubClassOf( ) + +# Class: (EC 6.* (ligase) inhibitor) + +AnnotationAssertion( "Any enzyme inhibitor that interferes with the action of a ligase (EC 6.*.*.*). Ligases are enzymes that catalyse the joining of two molecules with concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.") +AnnotationAssertion( "Wikipedia:Ligase") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "EC 6.* (ligase) inhibitors") +AnnotationAssertion(Annotation( "ChEBI") "EC 6.* inhibitor") +AnnotationAssertion(Annotation( "ChEBI") "EC 6.* inhibitors") +AnnotationAssertion(Annotation( "ChEBI") "EC 6.*.*.* inhibitor") +AnnotationAssertion(Annotation( "ChEBI") "EC 6.*.*.* inhibitors") +AnnotationAssertion(Annotation( "ChEBI") "ligase inhibitor") +AnnotationAssertion(Annotation( "ChEBI") "ligase inhibitors") +AnnotationAssertion( "CHEBI:75603") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "EC 6.* (ligase) inhibitor") +SubClassOf( ) + # Class: (eukaryotic metabolite) AnnotationAssertion( "Any metabolite produced during a metabolic reaction in eukaryotes, the taxon that include members of the fungi, plantae and animalia kingdoms.") @@ -15739,6 +29986,16 @@ AnnotationAssertion( "prokaryotic metabolite") SubClassOf( ) +# Class: (xenobiotic metabolite) + +AnnotationAssertion( "Any metabolite produced by metabolism of a xenobiotic compound.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "xenobiotic metabolites") +AnnotationAssertion( "CHEBI:76206") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "xenobiotic metabolite") +SubClassOf( ) + # Class: (greenhouse gas) AnnotationAssertion( "A gas in an atmosphere that absorbs and emits radiation within the thermal infrared range, so contributing to the 'greenhouse effect'.") @@ -15811,6 +30068,20 @@ AnnotationAssertion( "EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor") SubClassOf( ) +# Class: (EC 6.3.1.* (acid-ammonia/amine ligase) inhibitor) + +AnnotationAssertion( "An EC 6.3.* (C-N bond-forming ligase) inhibitor that interferes with the action of any acid-ammonia (or amine) ligase (EC 6.3.1.*).") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "EC 6.3.1.* (acid-ammonia/amine ligase) inhibitors") +AnnotationAssertion(Annotation( "ChEBI") "EC 6.3.1.* inhibitor") +AnnotationAssertion(Annotation( "ChEBI") "EC 6.3.1.* inhibitors") +AnnotationAssertion(Annotation( "ChEBI") "acid-ammonia (or amine) ligase inhibitor") +AnnotationAssertion(Annotation( "ChEBI") "acid-ammonia (or amine) ligase inhibitors") +AnnotationAssertion( "CHEBI:76823") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "EC 6.3.1.* (acid-ammonia/amine ligase) inhibitor") +SubClassOf( ) + # Class: (plant metabolite) AnnotationAssertion( "Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms.") @@ -15836,6 +30107,17 @@ AnnotationAssertion( "fungal metabolite") SubClassOf( ) +# Class: (human xenobiotic metabolite) + +AnnotationAssertion( "Any human metabolite produced by metabolism of a xenobiotic compound in humans.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "human xenobiotic metabolites") +AnnotationAssertion( "CHEBI:76967") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "human xenobiotic metabolite") +SubClassOf( ) +SubClassOf( ) + # Class: (bacterial metabolite) AnnotationAssertion( "Any prokaryotic metabolite produced during a metabolic reaction in bacteria.") @@ -15951,6 +30233,23 @@ AnnotationAssertion(rdfs:label "foo SubClassOf( ) SubClassOf( ) +# Class: (fatty acid anion 4:0) + +AnnotationAssertion( "Any saturated fatty acid anion containing 4 carbons. Formed by deprotonation of the carboxylic acid moiety. Major species at pH 7.3.") +AnnotationAssertion( "-1") +AnnotationAssertion( "C4H7O2") +AnnotationAssertion( "87.09718") +AnnotationAssertion( "87.04460") +AnnotationAssertion( "[O-]C([*])=O") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "UniProt") "fatty acid 4:0") +AnnotationAssertion( "CHEBI:78115") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "fatty acid anion 4:0") +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (food component) AnnotationAssertion( "A physiological role played by any substance that is distributed in foodstuffs. It includes materials derived from plants or animals, such as vitamins or minerals, as well as environmental contaminants.") @@ -16003,6 +30302,28 @@ AnnotationAssertion( "carbohydrates and carbohydrate derivatives") SubClassOf( ) +# Class: (fundamental metabolite) + +AnnotationAssertion( "Any metabolite produced by all living cells.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "essential metabolite") +AnnotationAssertion(Annotation( "ChEBI") "essential metabolites") +AnnotationAssertion(Annotation( "ChEBI") "fundamental metabolites") +AnnotationAssertion( "CHEBI:78675") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "fundamental metabolite") +SubClassOf( ) + +# Class: (olefinic compound) + +AnnotationAssertion( "Any organic molecular entity that contains at least one C=C bond.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "olefinic compounds") +AnnotationAssertion( "CHEBI:78840") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "olefinic compound") +SubClassOf( ) + # Class: (trivalent inorganic anion) AnnotationAssertion( "Any inorganic anion with a valency of three.") @@ -16033,6 +30354,16 @@ AnnotationAssertion( "monovalent inorganic anion") SubClassOf( ) +# Class: (elemental iron) + +AnnotationAssertion( "An elemental molecular entity in which all of the atoms have atomic number 26.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion( "CHEBI:82663") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "elemental iron") +SubClassOf( ) +SubClassOf( ) + # Class: (crustacean metabolite) AnnotationAssertion( "An animal metabolite produced by arthropods such as crabs, lobsters, crayfish, shrimps and krill.") @@ -16098,6 +30429,115 @@ SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (proteinogenic amino acid) + +AnnotationAssertion( "Any of the 23 alpha-amino acids that are precursors to proteins, and are incorporated into proteins during translation. The group includes the 20 amino acids encoded by the nuclear genes of eukaryotes together with selenocysteine, pyrrolysine, and N-formylmethionine. Apart from glycine, which is non-chiral, all have L configuration.") +AnnotationAssertion( "Wikipedia:Proteinogenic_amino_acid") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "canonical amino acid") +AnnotationAssertion(Annotation( "ChEBI") "canonical amino acids") +AnnotationAssertion(Annotation( "ChEBI") "proteinogenic amino acids") +AnnotationAssertion( "CHEBI:83813") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "proteinogenic amino acid") +SubClassOf( ) +SubClassOf( ) + +# Class: (non-proteinogenic amino acid) + +AnnotationAssertion( "Any amino-acid that is not naturally encoded in the genetic code of any organism.") +AnnotationAssertion( "Wikipedia:Non-proteinogenic_amino_acids") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "non-canonical amino acid") +AnnotationAssertion(Annotation( "ChEBI") "non-canonical amino acids") +AnnotationAssertion(Annotation( "ChEBI") "non-canonical amino-acid") +AnnotationAssertion(Annotation( "ChEBI") "non-canonical amino-acids") +AnnotationAssertion(Annotation( "ChEBI") "non-coded amino acid") +AnnotationAssertion(Annotation( "ChEBI") "non-coded amino acids") +AnnotationAssertion(Annotation( "ChEBI") "non-coded amino-acid") +AnnotationAssertion(Annotation( "ChEBI") "non-coded amino-acids") +AnnotationAssertion(Annotation( "ChEBI") "non-proteinogenic amino acids") +AnnotationAssertion(Annotation( "ChEBI") "non-proteinogenic amino-acid") +AnnotationAssertion(Annotation( "ChEBI") "non-proteinogenic amino-acids") +AnnotationAssertion( "CHEBI:83820") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "non-proteinogenic amino acid") +SubClassOf( ) + +# Class: (amino acid derivative) + +AnnotationAssertion( "Any derivative of an amino acid resulting from reaction at an amino group, carboxy group, side-chain functional group, or from the replacement of any hydrogen by a heteroatom. The definition normally excludes peptides containing amino acid residues.") +AnnotationAssertion( "CHEBI:25359") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "amino acid derivatives") +AnnotationAssertion(Annotation( "ChEBI") "modified amino acids") +AnnotationAssertion( "CHEBI:83821") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "amino acid derivative") +SubClassOf( ) + +# Class: (pregnane) + +AnnotationAssertion( "0") +AnnotationAssertion( "C21H36") +AnnotationAssertion( "InChI=1S/C21H36/c1-4-15-9-11-18-17-10-8-16-7-5-6-13-20(16,2)19(17)12-14-21(15,18)3/h15-19H,4-14H2,1-3H3/t15-,16?,17-,18-,19-,20-,21+/m0/s1") +AnnotationAssertion( "JWMFYGXQPXQEEM-WZBAXQLOSA-N") +AnnotationAssertion( "288.51054") +AnnotationAssertion( "288.28170") +AnnotationAssertion( "[H][C@]1(CC)CC[C@@]2([H])[C@]3([H])CCC4([H])CCCC[C@]4(C)[C@@]3([H])CC[C@]12C") +AnnotationAssertion(Annotation( "LIPID MAPS") "LIPID_MAPS_instance:LMST02030000") +AnnotationAssertion( "Wikipedia:Pregnane") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "pregnane") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion( "CHEBI:8386") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "pregnane") +SubClassOf( ) + +# Class: (non-proteinogenic alpha-amino acid) + +AnnotationAssertion( "Any alpha-amino acid which is not a member of the group of 23 proteinogenic amino acids.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "non-proteinogenic alpha-amino acids") +AnnotationAssertion(Annotation( "ChEBI") "non-proteinogenic alpha-amino-acid") +AnnotationAssertion(Annotation( "ChEBI") "non-proteinogenic alpha-amino-acids") +AnnotationAssertion( "CHEBI:83925") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "non-proteinogenic alpha-amino acid") +SubClassOf( ) +SubClassOf( ) + +# Class: (pentose phosphate) + +AnnotationAssertion( "Any phospho sugar that is the phosphate derivative of pentose.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "pentose phosphates") +AnnotationAssertion( "CHEBI:84055") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "pentose phosphate") +SubClassOf( ) +SubClassOf( ) + +# Class: (human urinary metabolite) + +AnnotationAssertion( "Any metabolite (endogenous or exogenous) found in human urine samples.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "human urinary metabolites") +AnnotationAssertion( "CHEBI:84087") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "human urinary metabolite") +SubClassOf( ) + +# Class: (hydroxyindoles) + +AnnotationAssertion( "Any member of the class of indoles carrying at least one hydroxy group.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion( "CHEBI:84729") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "hydroxyindoles") +SubClassOf( ) +SubClassOf( ) + # Class: (algal metabolite) AnnotationAssertion( "Any eukaryotic metabolite produced during a metabolic reaction in algae including unicellular organisms like chlorella and diatoms to multicellular organisms like giant kelps and brown algae.") @@ -16108,6 +30548,66 @@ AnnotationAssertion( "algal metabolite") SubClassOf( ) +# Class: (ADP(2-)) + +AnnotationAssertion( "An organophosphate oxoanion obtained by deprotonation of two of the three diphosphate OH groups of adenosine 5'-diphosphate.") +AnnotationAssertion( "-2") +AnnotationAssertion( "C10H13N5O10P2") +AnnotationAssertion( "InChI=1S/C10H15N5O10P2/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(24-10)1-23-27(21,22)25-26(18,19)20/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H2,11,12,13)(H2,18,19,20)/p-2/t4-,6-,7-,10-/m1/s1") +AnnotationAssertion( "XTWYTFMLZFPYCI-KQYNXXCUSA-L") +AnnotationAssertion( "425.18630") +AnnotationAssertion( "425.01486") +AnnotationAssertion( "Nc1ncnc2n(cnc12)[C@@H]1O[C@H](COP([O-])(=O)OP(O)([O-])=O)[C@@H](O)[C@H]1O") +AnnotationAssertion(Annotation( "Reaxys") "Reaxys:7558006") +AnnotationAssertion(Annotation( "IUPAC") Annotation( ) "5'-O-{[(hydroxyphosphinato)oxy]phosphinato}adenosine") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion( "CHEBI:87518") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "ADP(2-)") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (receptor modulator) + +AnnotationAssertion( "A drug that acts as an antagonist, agonist, reverse agonist, or in some other fashion when interacting with cellular receptors.") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "ChEBI") "receptor modulators") +AnnotationAssertion( "CHEBI:90710") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "receptor modulator") +SubClassOf( ) + +# Class: (vasopressin) + +AnnotationAssertion( "A family of cyclic nonapeptide hormones found in most mammals. Synthesised in the hypothalamus and stored in the post-pituitary, vasopressins play a key role in homeostasis, particularly in regulating the body's water content. Together with the similar neuropeptide oxytocin, they are believed to influence social cognition and behaviour.") +AnnotationAssertion( "0") +AnnotationAssertion( "C46H65N15O12S2.C46H65N13O12S2") +AnnotationAssertion( "2140.458") +AnnotationAssertion( "2138.86956") +AnnotationAssertion(Annotation( "ChemIDplus") "CAS:11000-17-2") +AnnotationAssertion( "KEGG:C00840") +AnnotationAssertion( "KEGG:D00101") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:18988842") +AnnotationAssertion(Annotation( "Europe PMC") "PMID:20445498") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Vasopressin") +AnnotationAssertion( "chebi_ontology") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "ADH") +AnnotationAssertion(Annotation( "ChEBI") "AVP") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "Antidiuretic hormone") +AnnotationAssertion(Annotation( "ChemIDplus") Annotation( ) "Inyectable de vasopresina") +AnnotationAssertion(Annotation( "ChemIDplus") Annotation( ) "Solute injectable de vasopressine") +AnnotationAssertion(Annotation( "KEGG_COMPOUND") "VP") +AnnotationAssertion(Annotation( "ChemIDplus") Annotation( ) "Vasopressini injectio") +AnnotationAssertion(Annotation( "ChEBI") "arginine vasopressin") +AnnotationAssertion(Annotation( "ChEBI") "argipressin") +AnnotationAssertion(Annotation( "ChemIDplus") "beta-Hypophamine") +AnnotationAssertion( "CHEBI:9937") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "vasopressin") +SubClassOf( ) +SubClassOf( ) + # Class: (cell) AnnotationAssertion(Annotation( "CARO:mah") "A material entity of anatomical origin (part of or deriving from an organism) that has as its parts a maximally connected cell compartment surrounded by a plasma membrane.") @@ -16129,16 +30629,6 @@ DisjointClasses( ) DisjointClasses( ) -# Class: (native cell) - -AnnotationAssertion(Annotation( "CARO:mah") "A cell that is found in a natural setting, which includes multicellular organism cells 'in vivo' (i.e. part of an organism), and unicellular organisms 'in environment' (i.e. part of a natural environment).") -AnnotationAssertion( "CARO:0000013") -AnnotationAssertion( "cell in vivo") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:comment "To accommodate unicellular organisms better, 'cell in vivo' has been re-labeled 'native cell' to better represent its intended meaning - that is, that it is a cell in the context of a multicellular organism or in a natural environment. 'Native' is intended to contrast with 'in vitro', which refers to cells or other biological entities that have been intentionally placed in a controlled, non-natural setting for the purpose of study or manipulation. (MAH 1.12.12).") -AnnotationAssertion(rdfs:label "native cell") -SubClassOf( ) - # Class: (fibroblast neural crest derived) AnnotationAssertion(Annotation( "https://orcid.org/0000-0001-5208-3432") "Any fibroblast that is deriived from the neural crest.") @@ -16151,6 +30641,7 @@ SubClassOf( ObjectSomeValuesFrom( "neuronal receptor cell (sensu Animalia)") AnnotationAssertion(rdfs:label "neuronal receptor cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) # Class: (early embryonic cell (metazoa)) @@ -16179,7 +30670,6 @@ AnnotationAssertion( "germ line stem cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) # Class: (male germ cell) @@ -16204,8 +30694,6 @@ AnnotationAssertion( "WBbt:0006799") AnnotationAssertion(rdfs:label "spermatocyte") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) # Class: (spermatid) @@ -16220,8 +30708,6 @@ AnnotationAssertion( "nematoblast") AnnotationAssertion(rdfs:label "spermatid") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) # Class: (sperm) @@ -16252,7 +30738,6 @@ AnnotationAssertion( "spermatogonial cell") AnnotationAssertion(rdfs:label "spermatogonium") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ) # Class: (female germ cell) @@ -16261,8 +30746,18 @@ AnnotationAssertion( "VHOG:0001530") AnnotationAssertion( "ncithesaurus:Egg") AnnotationAssertion(rdfs:label "female germ cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) +# Class: (female germ line stem cell) + +AnnotationAssertion(Annotation( "doi:10.1016/j.stem.2012.05.016") "A stem cell that is the precursor of female gametes.") +AnnotationAssertion( "FBbt:00004873") +AnnotationAssertion(rdfs:label "female germ line stem cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) +SubClassOf(Annotation( "true") ) + # Class: (oocyte) AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "ISBN:0721662544") "A female germ cell that has entered meiosis.") @@ -16285,7 +30780,6 @@ AnnotationAssertion( "oogonial cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) -SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) # Class: (egg cell) @@ -16301,12 +30795,27 @@ AnnotationAssertion( "mature oocyte") AnnotationAssertion( "ovum") AnnotationAssertion(rdfs:label "egg cell") -AnnotationAssertion( "https://www.swissbiopics.org/api/image/Egg_cell.svg"^^xsd:anyURI) -SubClassOf( ) +AnnotationAssertion( "https://www.swissbiopics.org/api/image/Egg_cell.svg"^^xsd:anyURI) SubClassOf(Annotation( "true") ) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (smooth muscle cell neural crest derived) + +AnnotationAssertion(Annotation( "https://orcid.org/0000-0001-5208-3432") "A smooth muscle cell derived from the neural crest.") +AnnotationAssertion(rdfs:label "smooth muscle cell neural crest derived") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (neural crest derived neuron) + +AnnotationAssertion( "neuron neural crest derived") +AnnotationAssertion(rdfs:label "neural crest derived neuron") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (glioblast) AnnotationAssertion(rdfs:label "glioblast") @@ -16334,8 +30843,7 @@ AnnotationAssertion( ) AnnotationAssertion(rdfs:comment "This term applies to metazoan. For plant stem cells, consider using PO:0004011 ‘initial cell’ or its parent PO:0004010 ‘meristematic cell’.") AnnotationAssertion(rdfs:label "stem cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) @@ -16346,7 +30854,7 @@ AnnotationAssertion( "unipotent stem cell") AnnotationAssertion( "unipotential stem cell") AnnotationAssertion(rdfs:label "single fate stem cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf( ) # Class: (epithelial fate stem cell) @@ -16375,6 +30883,7 @@ AnnotationAssertion( ) AnnotationAssertion(rdfs:comment "Markers differ between species, and two sets of markers have been described for mice. HSCs are reportedly CD34-positive, CD45-positive, CD48-negative, CD150-positive, CD133-positive, and CD244-negative.") AnnotationAssertion(rdfs:label "hematopoietic stem cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) @@ -16416,6 +30925,7 @@ AnnotationAssertion( "monocyte stem cell") AnnotationAssertion(rdfs:comment "Morphology: mononuclear cell, diameter 12-20 _M, non-granular, N/C ratio 3/1 - 4/1; markers: CD11b (shared with many other myeloid cells); location: Adult: bone marrow; fetal: liver, Yolk Sac; role or process: hematopoiesis, monocyte development; lineage: hematopoietic, myeloid.") AnnotationAssertion(rdfs:label "monoblast") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) SubClassOf( ObjectSomeValuesFrom( )) @@ -16428,7 +30938,7 @@ AnnotationAssertion( "multipotent cell") AnnotationAssertion( "multipotent stem cell") AnnotationAssertion(rdfs:label "multi fate stem cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) # Class: (common myeloid progenitor) @@ -16465,6 +30975,7 @@ AnnotationAssertion( ) AnnotationAssertion(rdfs:comment "MEPs are reportedly CD19-negative, CD34-negative, CD45RA-negative, CD110-positive, CD117-positive, and SCA1-negative and reportedly express the transcription factors GATA-1 and NF-E2.") AnnotationAssertion(rdfs:label "megakaryocyte-erythroid progenitor cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) SubClassOf( ObjectSomeValuesFrom( )) DisjointClasses( ) @@ -16486,6 +30997,7 @@ AnnotationAssertion( ) AnnotationAssertion(rdfs:comment "CLP are CD7-positive, CD10-positive, CD19-negative, CD34-positive, CD45RA-positive, CD79a-negative, CD127-positive, AA4.1-positive, RAG-negative, Sca-1-low, sIgM-negative, sIgD-negative, TdT-negative, Vpre-B-negative, and pre-BCR-negative. Expression of transcription factors include E2A-positive, EBF-positive, Ikaros-negative, PU.1-negative, and Pax5-negative.") AnnotationAssertion(rdfs:label "common lymphoid progenitor") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) # Class: (totipotent stem cell) @@ -16599,7 +31111,7 @@ AnnotationAssertion(Annotation( "VHOG:0001532") AnnotationAssertion( "XAO:0000031") AnnotationAssertion(rdfs:label "ciliated cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (ependymal cell) @@ -16627,8 +31139,8 @@ AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "epithelial cell") -AnnotationAssertion( "https://www.swissbiopics.org/api/image/Epithelial_cells.svg"^^xsd:anyURI) -SubClassOf( ) +AnnotationAssertion( "https://www.swissbiopics.org/api/image/Epithelial_cells.svg"^^xsd:anyURI) +SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) DisjointClasses( ) @@ -16637,11 +31149,13 @@ DisjointClasses( "GOC:tfm") "An epithelial cell that has a cilia.") AnnotationAssertion( "FMA:70605") AnnotationAssertion(rdfs:label "ciliated epithelial cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (duct epithelial cell) AnnotationAssertion(Annotation( "https://orcid.org/0000-0001-5208-3432") "An epithelial cell that is part of a duct.") AnnotationAssertion(rdfs:label "duct epithelial cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) # Class: (branched duct epithelial cell) @@ -16656,10 +31170,17 @@ AnnotationAssertion( "cuboidal endothelial cell of vascular tree") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "blood vessel endothelial cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (non-branched duct epithelial cell) + +AnnotationAssertion(rdfs:label "non-branched duct epithelial cell") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (columnar/cuboidal epithelial cell) AnnotationAssertion(Annotation( "GO:0002065") Annotation( "https://orcid.org/0000-0001-5208-3432") "A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube.") @@ -16696,7 +31217,7 @@ SubClassOf( ObjectSomeValuesFrom( "GOC:add") "A cell which moves among different tissues of the body, via blood, lymph, or other medium.") AnnotationAssertion(rdfs:label "circulating cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (blood cell) @@ -16705,6 +31226,7 @@ AnnotationAssertion( "MESH:D001773") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "blood cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) # Class: (epithelial cell of lung) @@ -16713,6 +31235,7 @@ AnnotationAssertion(Annotation( "BTO:0004299") AnnotationAssertion( "lung epithelial cell") AnnotationAssertion(rdfs:label "epithelial cell of lung") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ObjectSomeValuesFrom( )) # Class: (epithelial cell of pancreas) @@ -16723,8 +31246,6 @@ AnnotationAssertion( "pancreatic epithelial cell") AnnotationAssertion(rdfs:label "epithelial cell of pancreas") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) # Class: (T cell) @@ -16744,10 +31265,42 @@ AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "T cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) SubClassOf( ObjectSomeValuesFrom( )) DisjointClasses( ) +# Class: (osteoclast) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:tfm") Annotation( "GO_REF:0000031") Annotation( "ISBN:0781735149") Annotation( "PMID:10428500") Annotation( "PMID:15055519") Annotation( "PMID:17380158") "A specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue, which typically differentiates from monocytes. This cell has the following markers: tartrate-resistant acid phosphatase type 5-positive, PU.1-positive, c-fos-positive, nuclear factor NF-kappa-B p100 subunit-positive, tumor necrosis factor receptor superfamily member 11A-positive and macrophage colony-stimulating factor 1 receptor-positive.") +AnnotationAssertion( "BTO:0000968") +AnnotationAssertion( "CALOHA:TS-0721") +AnnotationAssertion( "FMA:66781") +AnnotationAssertion( "MESH:D010010") +AnnotationAssertion( "chondroclast") +AnnotationAssertion(rdfs:comment "Morphology: Highly vesicular; markers: Surface: RANK, cFMS (MCSF receptor); Secreted: cathepsin K and TRAP (tartate resistant acid phosphatase); transcription factors: PU.1, cFOS, MITF, NFkB (p52); role or process: tissue remodelling: bone resorption; lineage: hematopoietic, myeloid.") +AnnotationAssertion(rdfs:label "osteoclast") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) +SubClassOf(Annotation( "true") ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (granulocyte) + +AnnotationAssertion(Annotation( "GOC:amm") Annotation( "GOC:tfm") Annotation( "MESH:D006098") Annotation( "http://en.wikipedia.org/wiki/Granulocyte") "A leukocyte with abundant granules in the cytoplasm.") +AnnotationAssertion( ) +AnnotationAssertion( "BTO:0000539") +AnnotationAssertion( "BTO:0001026") +AnnotationAssertion( "CALOHA:TS-0422") +AnnotationAssertion( "FMA:62854") +AnnotationAssertion( "granular leucocyte") +AnnotationAssertion( "granular leukocyte") +AnnotationAssertion( "polymorphonuclear leukocyte") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "granulocyte") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) + # Class: (neuron associated cell) AnnotationAssertion(rdfs:label "neuron associated cell") @@ -16762,7 +31315,6 @@ AnnotationAssertion( "The term \"neuroepithelial cell\" is used to describe both this cell type and neurecto-epithelial cell (CL:0000710).") AnnotationAssertion(rdfs:label "sensory epithelial cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) SubClassOf( ) # Class: (interneuron) @@ -16799,13 +31351,31 @@ AnnotationAssertion( "MESH:D011984") AnnotationAssertion( "WBbt:0005759") AnnotationAssertion(rdfs:label "sensory neuron") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (bipolar neuron) + +AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "ISBN:0444009442") "A type of interneuron that has two neurites, usually an axon and a dendrite, extending from opposite poles of an ovoid cell body.") +AnnotationAssertion( "FMA:67282") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "bipolar neuron") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (multipolar neuron) + +AnnotationAssertion(Annotation( "FMA:67287") Annotation( "GOC:tfm") "A neuron with three or more neurites, usually an axon and multiple dendrites.") +AnnotationAssertion( "FMA:67287") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "multipolar neuron") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (autonomic neuron) AnnotationAssertion(Annotation( "GOC:tfm") "A neuron whose cell body is within an autonomic ganglion.") AnnotationAssertion( "FMA:80121") AnnotationAssertion(rdfs:label "autonomic neuron") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) # Class: (cholinergic neuron) @@ -16817,6 +31387,7 @@ AnnotationAssertion( "MESH:D059329") AnnotationAssertion( "WBbt:0006840") AnnotationAssertion(rdfs:label "cholinergic neuron") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (surface ectodermal cell) @@ -16853,6 +31424,7 @@ AnnotationAssertion(Annotation( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "basket cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) # Class: (cerebellar Golgi cell) @@ -16866,6 +31438,13 @@ AnnotationAssertion(rdfs:label "cere SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (granule cell) + +AnnotationAssertion(Annotation( ) "A neuron of the vertebrate central nervous system that is small in size. This general class includes small neurons in the granular layer of the cerebellar cortex, cerebral cortex neurons that are not pyramidal cells and small neurons without axons found in the olfactory bulb.") +AnnotationAssertion( "BTO:0003393") +AnnotationAssertion(rdfs:label "granule cell") +SubClassOf( ) + # Class: (Purkinje cell) AnnotationAssertion(Annotation( "MESH:D011689") "The output neuron of the cerebellar cortex.") @@ -16887,6 +31466,7 @@ AnnotationAssertion(Annotation( "BTO:0002316") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "stellate neuron") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (neuron associated cell (sensu Vertebrata)) @@ -16936,6 +31516,23 @@ AnnotationAssertion(rdfs:comment "As AnnotationAssertion(rdfs:label "astrocyte") SubClassOf( ) +# Class: (oligodendrocyte) + +AnnotationAssertion(Annotation( "MESH:D009836") Annotation( "http://en.wikipedia.org/wiki/Oligodendrocyte") "A class of large neuroglial (macroglial) cells in the central nervous system. Form the insulating myelin sheath of axons in the central nervous system.") +AnnotationAssertion( ) +AnnotationAssertion( "BTO:0000962") +AnnotationAssertion( "CALOHA:TS-0709") +AnnotationAssertion( "FMA:54540") +AnnotationAssertion(Annotation( "PMID:8734446") "OLs") +AnnotationAssertion( "oligodendroglia") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:comment "Oligodendrocytes are reportedly MDP-positive and CD4-negative.") +AnnotationAssertion(rdfs:label "oligodendrocyte") +SubClassOf(Annotation( "true") ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (neurectodermal cell) AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "ISBN:068340007X") "Ectoderm destined to be nervous tissue.") @@ -16973,6 +31570,7 @@ AnnotationAssertion(Annotation( "FMA:63879") AnnotationAssertion(rdfs:comment "Cultured human fibrocytes are MHCI-positive, MHCII-positive, CD1a-negative, CD3-negative, CD4-negative, CD8-negative, CD10-negative, CD11b-positive, CD13-positive, CD14-negative, CD16-negative, CD18-positive, CD19-negative, CD25-negative, CD29-positive, CD32-positive, CD33-negative, CD34-positive, CD38-negative, CD40-positive, CD44-negative, CD45RO-positive, CD49a-positive, CD49b-positive, CD49c-negative, CD49d-negative, CD49e-positive, CD49f-negative, CD56-negative, CD58-positive, CD61-positive, CD64-positive, CD70-negative, CD71-positive, CD80-positive, CD83-negative, CD86-positive, CD103-negative, CD105-positive, CD181-positive, CD182-negative, CD183-positive, CD184-positive, CD185-negative, CD186-negative, CD191-positive, CD192-negative, CD193-positive, CD194-positive, CD195-positive, CD196-negative, CD197-positive, CD199-positive, desmin-negative, F4/80-positive, Gr1-positive, LSP-1-positive, MHCI-positive, MHCII-positive, alpha-SMA-negative, TCRab-negative, TCRgd-negative, and vimentin-positive. Fibrocytes are also capable of secreting angiogenin, bFGF, CCL2, CCL3, CCL4, CCL8, CXCL1, type I collagen, type III collagen, CTGF, fibronectin, GM-CSF, IL-1a, IL-6, IL-8, IL-10, M-CSF, MMP-9, PDGF-A, TGF-alpha, TGF-beta1, TNF-alpha, and VEGF-A.") AnnotationAssertion(rdfs:label "fibrocyte") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) SubClassOf( ObjectSomeValuesFrom( )) @@ -17023,7 +31621,7 @@ SubClassOf( ObjectSomeValuesFrom( (professional antigen presenting cell) AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") "A cell capable of processing and presenting lipid and protein antigens to T cells in order to initiate an immune response.") -AnnotationAssertion(Annotation( ) "APC") +AnnotationAssertion(Annotation( ) "APC") AnnotationAssertion( ) AnnotationAssertion(rdfs:comment "Note change of name; nearly all somatic cells can present antigens to T cells via MHC Class I complexes leading to effector responses, but professional antigen presenting cells constitutively express MHC Class II as well as costimulatory molecules, and thus can initiate immune responses via T cells.") AnnotationAssertion(rdfs:label "professional antigen presenting cell") @@ -17060,9 +31658,6 @@ AnnotationAssertion( ) AnnotationAssertion(rdfs:label "melanocyte") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) -SubClassOf( ) # Class: (visual pigment cell) @@ -17086,7 +31681,7 @@ AnnotationAssertion(Annotation( "BTO:0003659") AnnotationAssertion( "FMA:86916") AnnotationAssertion(rdfs:label "secretory cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (exocrine cell) @@ -17096,7 +31691,6 @@ AnnotationAssertion( "exocrine cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -SubClassOf( ) # Class: (glycosaminoglycan secreting cell) @@ -17110,6 +31704,7 @@ SubClassOf( (protein secreting cell) AnnotationAssertion(rdfs:label "protein secreting cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (peptic cell) @@ -17124,6 +31719,13 @@ SubClassOf( ) SubClassOf( ) +# Class: (surfactant secreting cell) + +AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "ISBN:0721662544") "A cell that specializes in secretion of surfactant in the alveoli of the lung.") +AnnotationAssertion(rdfs:label "surfactant secreting cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) + # Class: (club cell) AnnotationAssertion(Annotation( "DOI:10.1183/09031936.00146609") Annotation( "DOI:10.1378/chest.12-2762") Annotation( "GOC:tfm") Annotation( "PMID:28128362") Annotation( "PMID:29874100") Annotation( "PMID:7905712") "A non-mucous, epithelial secretory cell that is part of the tracheobronchial tree. A club cell has short microvilli but no cilia. A club cell is able to multiply and differentiate into ciliated cells to regenerate the bronchiolar epithelium and it also protects the tracheobronchial epithelium.") @@ -17176,8 +31778,7 @@ AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "endocrine cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))))) -SubClassOf( ) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))))) SubClassOf( ObjectSomeValuesFrom( )) # Class: (enteroendocrine cell) @@ -17204,6 +31805,7 @@ AnnotationAssertion(Annotation( "neuroendocrine cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ) @@ -17222,19 +31824,94 @@ SubClassOf( ObjectSomeValuesFrom( (peptide hormone secreting cell) AnnotationAssertion(rdfs:label "peptide hormone secreting cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (insulin secreting cell) AnnotationAssertion( "BTO:0000783") AnnotationAssertion(rdfs:label "insulin secreting cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (type B pancreatic cell) + +AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "ISBN:0517223651") Annotation( "http://en.wikipedia.org/wiki/Pancreatic_b_cell") "A cell that secretes insulin and is located towards the center of the islets of Langerhans.") +AnnotationAssertion( ) +AnnotationAssertion(Annotation( "ZFA:0009102") "beta cell") +AnnotationAssertion( "BTO:0000783") +AnnotationAssertion( "EV:0200009") +AnnotationAssertion( "FMA:70586") +AnnotationAssertion( "MA:0002419") +AnnotationAssertion( "ncithesaurus:Beta_Cell") +AnnotationAssertion(Annotation( "FMA:70586") "B-cell of pancreatic islet") +AnnotationAssertion(Annotation( "FMA:70586") "beta cell of pancreatic islet") +AnnotationAssertion(Annotation( "FMA:70586") "insulin-secreting cell") +AnnotationAssertion( "pancreatic B cell") +AnnotationAssertion(Annotation( "FMA:70586") "pancreatic B-cell") +AnnotationAssertion(Annotation( "FMA:70586") "pancreatic beta cell") +AnnotationAssertion(Annotation( "MA:0002419") "pancreatic islet core") +AnnotationAssertion(Annotation( "FMA:70586") "type B enteroendocrine cell") +AnnotationAssertion(Annotation( "MA:0002419") "beta cell islet") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:comment "Pancreatic beta cells are also reportedly CD284-positive. Upon activation, they upregulate their CD14 expression.") +AnnotationAssertion(rdfs:label "type B pancreatic cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) +SubClassOf(Annotation( "true") ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (glucagon secreting cell) + +AnnotationAssertion(Annotation( "GOC:tfm") "A cell that secretes glucagon.") +AnnotationAssertion( "FMA:84045") +AnnotationAssertion( "glucagon-secreting cell") +AnnotationAssertion(rdfs:label "glucagon secreting cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (pancreatic A cell) + +AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "ISBN:0721662544") "A type of enteocrine cell found in the periphery of the islets of Langerhans that secretes glucagon.") +AnnotationAssertion( ) +AnnotationAssertion( "BTO:0000990") +AnnotationAssertion( "FMA:70585") +AnnotationAssertion( "MESH:D050416") +AnnotationAssertion( "alpha cell of islet of Langerhans") +AnnotationAssertion( "pancreatic alpha cell") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "pancreatic A cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) # Class: (somatostatin secreting cell) AnnotationAssertion(rdfs:label "somatostatin secreting cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (pancreatic D cell) + +AnnotationAssertion(Annotation( "FMA:0517223651") Annotation( "GOC:tfm") "A D cell located in the pancreas. Peripherally placed within the islets like type A cells; contains somatostatin.") +AnnotationAssertion( ) +AnnotationAssertion( "BTO:0000803") +AnnotationAssertion( "FMA:70587") +AnnotationAssertion( "D-cell of pancreatic islet") +AnnotationAssertion( "delta cell of islet") +AnnotationAssertion( "delta cell of pancreatic islet") +AnnotationAssertion( "pancreatic D-cell") +AnnotationAssertion( "pancreatic delta cell") +AnnotationAssertion( "somatostatin-secreting pancreatic cell") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "pancreatic D cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) # Class: (steroid hormone secreting cell) AnnotationAssertion(rdfs:label "steroid hormone secreting cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (luteal cell) @@ -17254,6 +31931,7 @@ SubClassOf( ObjectSomeValuesFrom( (testosterone secreting cell) AnnotationAssertion(rdfs:label "testosterone secreting cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (Leydig cell) @@ -17271,6 +31949,11 @@ SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (progesterone secreting cell) + +AnnotationAssertion(rdfs:label "progesterone secreting cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (hepatocyte) AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "ISBN:0412046911") Annotation( "MESH:D022781") Annotation( "PMID:19717280") Annotation( "http://en.wikipedia.org/wiki/Hepatocyte") "The main structural component of the liver. They are specialized epithelial cells that are organized into interconnected plates called lobules. Majority of cell population of liver, polygonal in shape, arranged in plates or trabeculae between sinusoids; may have single nucleus or binucleated.") @@ -17336,8 +32019,7 @@ AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "cell of skeletal muscle") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (slow muscle cell) @@ -17381,7 +32063,6 @@ AnnotationAssertion( "receptor cell") AnnotationAssertion(rdfs:label "sensory receptor cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ) # Class: (pain receptor cell) @@ -17397,6 +32078,12 @@ SubClassOf( "MESH:D008465") "A cell specialized to transduce mechanical stimuli and relay that information centrally in the nervous system.") AnnotationAssertion(Annotation( "MP:0000972") "mechanoreceptor") AnnotationAssertion(rdfs:label "mechanoreceptor cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (touch receptor cell) + +AnnotationAssertion(rdfs:label "touch receptor cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (auditory hair cell) @@ -17412,6 +32099,7 @@ SubClassOf( ObjectSomeValuesFrom( "MESH:D002628") "A cell specialized to detect chemical substances and relay that information centrally in the nervous system. Chemoreceptors may monitor external stimuli, as in taste and olfaction, or internal stimuli, such as the concentrations of oxygen and carbon dioxide in the blood.") AnnotationAssertion(rdfs:label "chemoreceptor cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (olfactory receptor cell) @@ -17424,6 +32112,7 @@ AnnotationAssertion( "olfactory receptor neuron") AnnotationAssertion( "olfactory sensory neuron") AnnotationAssertion(rdfs:label "olfactory receptor cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ObjectSomeValuesFrom( )) # Class: (taste receptor cell) @@ -17432,6 +32121,7 @@ AnnotationAssertion(Annotation( "FMA:67910") AnnotationAssertion( "taste bud cell") AnnotationAssertion(rdfs:label "taste receptor cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) @@ -17442,7 +32132,7 @@ AnnotationAssertion( "CALOHA:TS-0868") AnnotationAssertion( "FMA:86740") AnnotationAssertion(rdfs:label "photoreceptor cell") -AnnotationAssertion( "https://www.swissbiopics.org/api/image/Photoreceptor_cell.svg"^^xsd:anyURI) +AnnotationAssertion( "https://www.swissbiopics.org/api/image/Photoreceptor_cell.svg"^^xsd:anyURI) EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) @@ -17483,16 +32173,36 @@ AnnotationAssertion( "FMA:72298") AnnotationAssertion( "VHOG:0001348") AnnotationAssertion(rdfs:label "Sertoli cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf(Annotation( "true") ) SubClassOf( ) +# Class: (insulating cell) + +AnnotationAssertion(rdfs:label "insulating cell") +SubClassOf( ) + +# Class: (myelinating Schwann cell) + +AnnotationAssertion(Annotation( "GOC:cvs") Annotation( "GOC:tfm") Annotation( "MESH:D012583") "A neuroglial cell of the peripheral nervous system which forms the insulating myelin sheaths of peripheral axons.") +AnnotationAssertion( "Schwann cell") +AnnotationAssertion( "peripheral neuroglial cell") +AnnotationAssertion( "CALOHA:TS-0898") +AnnotationAssertion( "FMA:62121") +AnnotationAssertion( "neurilemmal cell") +AnnotationAssertion(rdfs:label "myelinating Schwann cell") +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (motile cell) AnnotationAssertion(Annotation( "FB:ma") "A cell that moves by its own activities.") AnnotationAssertion(rdfs:label "motile cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (ectodermal cell) @@ -17528,19 +32238,19 @@ AnnotationAssertion(Annotation( "FMA:68647") AnnotationAssertion( "non-nucleated cell") AnnotationAssertion(rdfs:label "anucleate cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) DisjointClasses( ) # Class: (single nucleate cell) AnnotationAssertion(Annotation( "FB:ma") Annotation( "GOC:tfm") "A cell with a single nucleus.") AnnotationAssertion(rdfs:label "single nucleate cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (binucleate cell) AnnotationAssertion(rdfs:label "binucleate cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (multinucleate cell) @@ -17551,7 +32261,7 @@ AnnotationAssertion( "syncytial cell") AnnotationAssertion( "syncytium") AnnotationAssertion(rdfs:label "multinucleate cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (erythrocyte) @@ -17565,6 +32275,7 @@ AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "erythrocyte") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) SubClassOf( ObjectSomeValuesFrom( )) @@ -17597,7 +32308,7 @@ AnnotationAssertion( "FMA:83806") AnnotationAssertion( "MESH:D010586") AnnotationAssertion(rdfs:label "phagocyte") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ) @@ -17617,6 +32328,7 @@ AnnotationAssertion( ) AnnotationAssertion(rdfs:comment "Morphology: Diameter 30_M-80 _M, abundant cytoplasm, low N/C ratio, eccentric nucleus. Irregular shape with pseudopods, highly adhesive. Contain vacuoles and phagosomes, may contain azurophilic granules; markers: Mouse & Human: CD68, in most cases CD11b. Mouse: in most cases F4/80+; role or process: immune, antigen presentation, & tissue remodelling; lineage: hematopoietic, myeloid.") AnnotationAssertion(rdfs:label "macrophage") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) SubClassOf( ObjectSomeValuesFrom( )) @@ -17636,6 +32348,7 @@ AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "B cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) SubClassOf( ObjectSomeValuesFrom( )) @@ -17646,6 +32359,12 @@ SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (brush border epithelial cell) + +AnnotationAssertion(rdfs:label "brush border epithelial cell") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (stratified squamous epithelial cell) AnnotationAssertion( ) @@ -17674,18 +32393,17 @@ AnnotationAssertion( ) AnnotationAssertion(rdfs:label "transitional epithelial cell") SubClassOf( ) -SubClassOf( ) # Class: (eukaryotic cell) AnnotationAssertion( "MESH:D005057") AnnotationAssertion(rdfs:label "eukaryotic cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (Eumycetozoan cell) AnnotationAssertion(rdfs:label "Eumycetozoan cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) # Class: (eye photoreceptor cell) @@ -17694,13 +32412,14 @@ AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "eye photoreceptor cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) # Class: (structural cell) AnnotationAssertion(Annotation( "TAIR:sr") "A cell whose primary function is to provide structural support, to provide strength and physical integrity to the organism.") AnnotationAssertion(rdfs:label "structural cell") -SubClassOf( ) +SubClassOf( ) # Class: (somatotropin secreting cell) @@ -17708,6 +32427,7 @@ AnnotationAssertion(Annotation( "growth hormone secreting cell") AnnotationAssertion( "somatotrophin secreting cell") AnnotationAssertion(rdfs:label "somatotropin secreting cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (gamete) @@ -17718,6 +32438,7 @@ AnnotationAssertion( "haploid nucleated cell") AnnotationAssertion( "haploid germ cell") AnnotationAssertion(rdfs:label "gamete") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) # Class: (crystallin accumulating cell) @@ -17730,10 +32451,8 @@ SubClassOf( (tracheal epithelial cell) AnnotationAssertion(Annotation( "GOC:tfm") "An epithelial cell found in the trachea.") -AnnotationAssertion( ) AnnotationAssertion( "FMA:74793") AnnotationAssertion( "tracheocyte") -AnnotationAssertion( ) AnnotationAssertion(rdfs:comment "This class is for the vertebrate tracheal structure. For the analagous insect cell type, see 'respiratory tube epithelial cell'") AnnotationAssertion(rdfs:label "tracheal epithelial cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) @@ -17757,6 +32476,7 @@ AnnotationAssertion( ) AnnotationAssertion(rdfs:comment "Keratinocytes are reportedly CDw210a-negative, CDw210b-positive, CD281-positive, CD282-positive, CD285-positive, IL22Ra1-positive, Human keratinocytes are reportedly capable of secreting BD-2, BD-3, hCAP-18, CXCL1, CXCL5, CXCL8, elafin, MMP-3, NGAL, PDGF-A, S100A7, S100A8, and S100A9. Transcription factors: STAT3-positive.") AnnotationAssertion(rdfs:label "keratinocyte") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) SubClassOf(Annotation( "true") ) SubClassOf( ObjectSomeValuesFrom( )) @@ -17772,11 +32492,27 @@ AnnotationAssertion( "serous secreting cell") SubClassOf( ) +# Class: (milk secreting cell) + +AnnotationAssertion(rdfs:label "milk secreting cell") +SubClassOf( ) + +# Class: (sebum secreting cell) + +AnnotationAssertion(Annotation( "MESH:D012629") "A cell secreting sebun, an oily substance secreted by sebaceous glands, composed of keratin, fat, and cellular debris.") +AnnotationAssertion( ) +AnnotationAssertion( "sebocyte") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "sebum secreting cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) + # Class: (mucus secreting cell) AnnotationAssertion( "BTO:0003689") AnnotationAssertion( "mucous cell") AnnotationAssertion(rdfs:label "mucus secreting cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) @@ -17807,7 +32543,7 @@ SubClassOf( (oxygen accumulating cell) AnnotationAssertion(rdfs:label "oxygen accumulating cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (migratory neural crest cell) @@ -17831,6 +32567,7 @@ AnnotationAssertion(Annotation( "FMA:69262") AnnotationAssertion(Annotation( "FMA:69262") "medullary chromaffin cell of adrenal gland") AnnotationAssertion(rdfs:label "adrenal medulla chromaffin cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) SubClassOf(Annotation( "true") ) SubClassOf( ) @@ -17846,13 +32583,21 @@ SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (hair follicle dermal papilla cell) + +AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:9893172") "A specialized mesenchymal cell that resides in the dermal papilla located at the bottom of hair follicles. This cell plays a pivotal roles in hair formation, growth, and cycling.") +AnnotationAssertion(rdfs:comment "Are these really all stem cells?") +AnnotationAssertion(rdfs:label "hair follicle dermal papilla cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (scleral cell) AnnotationAssertion(Annotation( "GOC:add") "A cell of the sclera of the eye.") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "scleral cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) # Class: (choroidal cell of the eye) @@ -17861,15 +32606,13 @@ AnnotationAssertion(Annotation( ) AnnotationAssertion(rdfs:label "choroidal cell of the eye") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) # Class: (extraembryonic cell) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "extraembryonic cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (amnioserosal cell) @@ -17913,6 +32656,7 @@ AnnotationAssertion(Annotation( "FMA:86767") AnnotationAssertion(rdfs:comment "Multi-potency demonstrated ex vivo. At the time of writing, it is unclear whether the endogenous population differentiates into multiple cell types in vivo.") AnnotationAssertion(rdfs:label "multi-potent skeletal muscle stem cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) # Class: (stratified epithelial stem cell) @@ -17920,6 +32664,25 @@ SubClassOf(Annotation( AnnotationAssertion(rdfs:label "stratified epithelial stem cell") SubClassOf( ) +# Class: (sphincter associated smooth muscle cell) + +AnnotationAssertion(Annotation( "GOC:cjm") "A smooth muscle cell that is part of a sphincter. A sphincter is a typically circular muscle that normally maintains constriction of a natural body passage or orifice and which relaxes as required by normal physiological functioning.") +AnnotationAssertion(rdfs:label "sphincter associated smooth muscle cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) + +# Class: (vascular associated smooth muscle cell) + +AnnotationAssertion(Annotation( "GOC:dsd") Annotation( "GOC:tfm") "A smooth muscle cell associated with the vasculature.") +AnnotationAssertion( ) +AnnotationAssertion( "VSMC") +AnnotationAssertion( "vascular smooth muscle cell") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "vascular associated smooth muscle cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) +SubClassOf( ) + # Class: (epidermal cell) AnnotationAssertion(Annotation( "Flybase:dsj") Annotation( "MA:ma") "An epithelial cell of the integument (the outer layer of an organism).") @@ -17930,6 +32693,7 @@ AnnotationAssertion( "FMA:62411") "cell of epidermis") AnnotationAssertion(Annotation( "FMA:62411") "epithelial cell of skin") AnnotationAssertion(rdfs:label "epidermal cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) # Class: (animal zygote) @@ -17940,9 +32704,15 @@ AnnotationAssertion( "EHDAA2:0004546") AnnotationAssertion( "FMA:72395") AnnotationAssertion(rdfs:label "animal zygote") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) +# Class: (tracheoblast) + +AnnotationAssertion(rdfs:label "tracheoblast") +SubClassOf( ) + # Class: (prohemocyte (sensu Nematoda and Protostomia)) AnnotationAssertion(Annotation( "doi:10.1016/B978-012369493-5.50008-0") "A precursor of mature hemocytes.") @@ -17951,6 +32721,11 @@ AnnotationAssertion( "prohemocyte (sensu Nematoda and Protostomia)") SubClassOf( ) +# Class: (attachment cell) + +AnnotationAssertion(rdfs:label "attachment cell") +SubClassOf( ) + # Class: (hemocyte (sensu Arthropoda)) AnnotationAssertion(Annotation( "doi:10.1016/B978-012369493-5.50008-0") "A blood cell of the circulatory system of arthropods.") @@ -17960,6 +32735,16 @@ SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (tendon cell) + +AnnotationAssertion(Annotation( "GOC:NV") Annotation( "GOC:tfm") Annotation( "PMID:957445") "An elongated fibrocyte that is part of a tendon. The cytoplasm is stretched between the collagen fibres of the tendon. They have a central cell nucleus with a prominent nucleolus. Tendon cells have a well-developed rough endoplasmic reticulum and they are responsible for synthesis and turnover of tendon fibres and ground substance.") +AnnotationAssertion( "muscle attachment cell") +AnnotationAssertion( "tenocyte") +AnnotationAssertion(rdfs:label "tendon cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) +SubClassOf( ) + # Class: (blood cell (sensu Nematoda and Protostomia)) AnnotationAssertion( ) @@ -17972,6 +32757,12 @@ AnnotationAssertion(Annotation( "electrically responsive cell") SubClassOf( ) +# Class: (ganglion interneuron) + +AnnotationAssertion(rdfs:label "ganglion interneuron") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) + # Class: (CNS interneuron) AnnotationAssertion(Annotation( "doi:10.1016/B978-0-12-817424-1.00001-X") "An interneuron that has its cell body in a central nervous system.") @@ -17979,6 +32770,7 @@ AnnotationAssertion( ) AnnotationAssertion(rdfs:comment "Interneurons are commonly described as being only found in the central nervous system. However, in CL we define 'interneuron' more broadly as any neuron that is neither a motor neuron nor a sensory neuron, regardless of its location, so we need this term to refer strictly to interneurons of the central nervous system.") AnnotationAssertion(rdfs:label "CNS interneuron") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (electrically signaling cell) @@ -17991,6 +32783,7 @@ SubClassOf( "BTO:0001277") AnnotationAssertion( "CALOHA:TS-0949") AnnotationAssertion(rdfs:label "male gamete") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) SubClassOf(Annotation( "true") ) @@ -17998,13 +32791,15 @@ SubClassOf(Annotation( AnnotationAssertion(Annotation( "https://bio.libretexts.org/Bookshelves/Introductory_and_General_Biology/Biology_(Kimball)/07%3A_Cell_Division/7.04%3A_Polyploidy"^^xsd:anyURI) Annotation( "FB:ma") Annotation( "PMID:32646579") "A cell that contains more than two haploid sets of chromosomes.") AnnotationAssertion(rdfs:label "polyploid cell") -SubClassOf( ) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (haploid cell) AnnotationAssertion(Annotation( "FB:ma") Annotation( "GOC:tfm") "A cell whose nucleus contains a single haploid genome.") +AnnotationAssertion( ) +AnnotationAssertion( ) AnnotationAssertion(rdfs:label "haploid cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (endopolyploid cell) @@ -18033,11 +32828,13 @@ SubClassOf( "GOC:tfm") "A peptide hormone secreting cell pituitary that produces luteinizing hormone.") AnnotationAssertion(rdfs:label "luteinizing hormone secreting cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (prolactin secreting cell) AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "SANBI:mhl") "A peptide hormone cell that secretes prolactin.") AnnotationAssertion(rdfs:label "prolactin secreting cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (melanocyte stimulating hormone secreting cell) @@ -18046,10 +32843,28 @@ AnnotationAssertion( "melanotrope") AnnotationAssertion( "melanotroph") AnnotationAssertion(rdfs:label "melanocyte stimulating hormone secreting cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (follicle stem cell (sensu Arthropoda)) + +AnnotationAssertion(Annotation( "doi:10.1016/B978-012369493-5.50005-5") Annotation( "doi:10.1038/s41467-020-19361-0") Annotation( "doi:10.1242/dev.121.11.3797") "A stem cell that gives rise to the follicle cells that surround the oocyte in female arthropods.") +AnnotationAssertion(Annotation( "doi:10.1016/j.devcel.2005.08.012") "somatic stem cell") +AnnotationAssertion( "FBbt:00004903") +AnnotationAssertion(rdfs:label "follicle stem cell (sensu Arthropoda)") +SubClassOf( ) +SubClassOf(Annotation( "https://github.com/obophenotype/cell-ontology/issues/1943") ObjectSomeValuesFrom( )) # Class: (calcitonin secreting cell) AnnotationAssertion(rdfs:label "calcitonin secreting cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (obliquely striated muscle cell) + +AnnotationAssertion(Annotation( "GOC:DOS") Annotation( "PMID:8720463") "A muscle cell in which the fibers are organised into sarcomeres but in which adjacent myofibrils are offset from each other, producing an oblique banding pattern.") +AnnotationAssertion(rdfs:comment "Examples include the somatic muscles of nemotodes and cephalopods.") +AnnotationAssertion(rdfs:label "obliquely striated muscle cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) # Class: (chief cell of parathyroid gland) @@ -18107,6 +32922,7 @@ AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "dendritic cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) DisjointClasses( ) @@ -18122,14 +32938,38 @@ AnnotationAssertion( ) AnnotationAssertion(rdfs:comment "Originally described in the dendritic cell ontology (DC_CL:0000021 )(PMID:19243617). These cells are also CD1a-high, CD14-negative, CD207-positive (langerin), CD324-positive (E-cadherin), and DCIR-positive. They reside in the epidermis.") AnnotationAssertion(rdfs:label "Langerhans cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (epinephrine secreting cell) + +AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:12438093") "A cell capable of producing epinephrine. Epiniphrine is synthesized from norepiniphrine by the actions of the phenylethanolamine N-methyltransferase enzyme, which is expressed in the adrenal glands, androgenic neurons, and in other cell types.") +AnnotationAssertion(Annotation( "GO:0048242") "adrenaline secreting cell") +AnnotationAssertion( "epinephrin secreting cell") +AnnotationAssertion(rdfs:label "epinephrine secreting cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (mineralocorticoid secreting cell) + +AnnotationAssertion(rdfs:label "mineralocorticoid secreting cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (biogenic amine secreting cell) AnnotationAssertion(rdfs:label "biogenic amine secreting cell") SubClassOf( ) +# Class: (serotonin secreting cell) + +AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:19630576") "A cell type that secretes 5-Hydroxytryptamine (serotonin).") +AnnotationAssertion( "5-HT secreting cell") +AnnotationAssertion( "5-Hydroxytryptamine secreting cell") +AnnotationAssertion(rdfs:label "serotonin secreting cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + # Class: (noradrenergic cell) AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "ISBN:068340007X") "A cell capable of producting norepiniphrine. Norepiniphrine is a catecholamine with multiple roles including as a hormone and a neurotransmitter. In addition, epiniphrine is synthesized from norepiniphrine by the actions of the phenylethanolamine N-methyltransferase enzyme.") @@ -18137,11 +32977,13 @@ AnnotationAssertion( "norepinephrin secreting cell") AnnotationAssertion( "norepinephrine secreting cell") AnnotationAssertion(rdfs:label "noradrenergic cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) # Class: (glucocorticoid secreting cell) AnnotationAssertion(rdfs:label "glucocorticoid secreting cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (adrenocorticotropic hormone secreting cell) @@ -18152,12 +32994,13 @@ AnnotationAssertion( "corticotropin hormone secreting cell") AnnotationAssertion(Annotation( "GO:0051458") "corticotropin secreting cell") AnnotationAssertion(rdfs:label "adrenocorticotropic hormone secreting cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (defensive cell) AnnotationAssertion(Annotation( "JB:jb") "A cell whose primary function is to protect the organism.") AnnotationAssertion(rdfs:label "defensive cell") -SubClassOf( ) +SubClassOf( ) # Class: (follicle cell of egg chamber) @@ -18293,6 +33136,7 @@ AnnotationAssertion( "cardiac muscle progenitor cell") AnnotationAssertion( "cardiomyocyte progenitor cell") AnnotationAssertion(rdfs:label "cardiac muscle myoblast") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) # Class: (smooth muscle myoblast) @@ -18303,8 +33147,6 @@ AnnotationAssertion(Annotation( "satellite cell") AnnotationAssertion(rdfs:label "smooth muscle myoblast") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) # Class: (skeletal muscle myoblast) @@ -18313,16 +33155,13 @@ AnnotationAssertion( "skeletal myoblast") AnnotationAssertion(rdfs:label "skeletal muscle myoblast") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) # Class: (fungal cell) AnnotationAssertion(rdfs:label "fungal cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -DisjointClasses( ) # Class: (syncytiotrophoblast cell) @@ -18337,7 +33176,7 @@ AnnotationAssertion( "syncytiotrophoblast cell") AnnotationAssertion(rdfs:seeAlso "https://github.com/obophenotype/cell-ontology/issues/2100") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) # Class: (afferent neuron) @@ -18385,8 +33224,6 @@ AnnotationAssertion( "Derived from UBERON:0002342 neural crest.") AnnotationAssertion(rdfs:label "melanoblast") SubClassOf( ) -SubClassOf( ) -SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) # Class: (lymphocyte) @@ -18401,6 +33238,7 @@ AnnotationAssertion( ) AnnotationAssertion(rdfs:comment "Editors note: consider adding taxon constraint to vertebrata (PMID:18025161)") AnnotationAssertion(rdfs:label "lymphocyte") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) SubClassOf( ObjectSomeValuesFrom( )) DisjointClasses( ) @@ -18413,6 +33251,7 @@ AnnotationAssertion(Annotation( "pronormoblast") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "proerythroblast") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) SubClassOf( ObjectSomeValuesFrom( )) @@ -18425,6 +33264,7 @@ AnnotationAssertion(Annotation( "ISBN:0721601464") "early normoblast") AnnotationAssertion(Annotation( "ISBN:0721601464") "prorubricyte") AnnotationAssertion(rdfs:label "basophilic erythroblast") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) SubClassOf( ObjectSomeValuesFrom( )) @@ -18439,6 +33279,7 @@ AnnotationAssertion(Annotation( "ISBN:0721601464") "polychromatophilic normoblast") AnnotationAssertion(Annotation( "ISBN:0721601464") "rubricyte") AnnotationAssertion(rdfs:label "polychromatophilic erythroblast") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) SubClassOf( ObjectSomeValuesFrom( )) @@ -18452,6 +33293,7 @@ AnnotationAssertion( "ISBN:0721601464") "orthochromatic normoblast") AnnotationAssertion(Annotation( "ISBN:0721601464") "pyknotic eto enrythroblast") AnnotationAssertion(rdfs:label "orthochromatic erythroblast") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) SubClassOf( ObjectSomeValuesFrom( )) @@ -18476,6 +33318,7 @@ AnnotationAssertion( ) AnnotationAssertion(rdfs:comment "Lineage negative is described here as CD2-negative, CD3-negative, CD4-negative, CD5-negative, CD8a-negative, CD14-negative, CD19-negative, CD20-negative, CD56-negative, Ly6g-negative, and Ter119-negative.") AnnotationAssertion(rdfs:label "megakaryocyte progenitor cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) SubClassOf( ObjectSomeValuesFrom( )) @@ -18517,6 +33360,7 @@ AnnotationAssertion(Annotation( ) AnnotationAssertion(rdfs:comment "Originally described in the dendritic cell ontology (DC_CL:0000042)(PMID:19243617). GMPs are reportedly CD16-positive, CD32-positive, CD34-positive, CD38-positive, CD45RA-positive, CD110-negative, CD117-positive, CD123-positive, and SCA1-negative.") AnnotationAssertion(rdfs:label "granulocyte monocyte progenitor cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) SubClassOf( ObjectSomeValuesFrom( )) @@ -18528,6 +33372,7 @@ AnnotationAssertion( "MESH:D012156") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "reticulocyte") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) SubClassOf( ObjectSomeValuesFrom( )) @@ -18540,6 +33385,7 @@ AnnotationAssertion( ) AnnotationAssertion(rdfs:comment "Morphology: Mononuclear cell, diameter 14-18 _M, fine azurophilic granules; markers: CD11b (shared with many other myeloid cells); location: Adult: bone marrow; Fetal: Liver, Yolk Sac; role or process: hematopoiesis, monocyte development; lineage: hematopoietic, myeloid.") AnnotationAssertion(rdfs:label "promonocyte") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) SubClassOf( ObjectSomeValuesFrom( )) @@ -18550,8 +33396,8 @@ AnnotationAssertion( "BTO:0004044") AnnotationAssertion( "FMA:67766") AnnotationAssertion( "amacrine neuron") -AnnotationAssertion(Annotation( "doi:10.1038/s41598-020-66092-9") Annotation( ) "AC") -AnnotationAssertion(Annotation( "doi:10.1038/s41598-020-66092-9") Annotation( ) Annotation( ) "ACs") +AnnotationAssertion(Annotation( "doi:10.1038/s41598-020-66092-9") Annotation( ) "AC") +AnnotationAssertion(Annotation( "doi:10.1038/s41598-020-66092-9") Annotation( ) Annotation( ) "ACs") AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "amacrine cell") @@ -18560,6 +33406,16 @@ SubClassOf( ObjectSomeValuesFrom( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (nucleate erythrocyte) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOc:tfm") "An erythrocyte having a nucleus.") +AnnotationAssertion( "RBC") +AnnotationAssertion( "red blood cell") +AnnotationAssertion(rdfs:label "nucleate erythrocyte") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (angioblastic mesenchymal cell) AnnotationAssertion(Annotation( "GOC:dsd") Annotation( "GOC:tfm") Annotation( "PMID:12768659") "A mesenchymal stem cell capable of developing into blood vessel endothelium.") @@ -18567,6 +33423,7 @@ AnnotationAssertion( "chondroplast") AnnotationAssertion(rdfs:comment "These cells are reportedly CD31-positive, CD34-positive, CD144-positive, CD309-positive, and TAL1-positive.") AnnotationAssertion(rdfs:label "angioblastic mesenchymal cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) SubClassOf( ObjectSomeValuesFrom( )) @@ -18580,6 +33437,13 @@ AnnotationAssertion( "amine precursor uptake and decarboxylation cell") SubClassOf( ) +# Class: (cardiac mesenchymal cell) + +AnnotationAssertion(Annotation( "PMID:18816864") "A mesenchymal cell found in the developing heart and that develops into some part of the heart. These cells derive from intra- and extra-cardiac sources, including the endocardium, epicardium, neural crest, and second heart field.") +AnnotationAssertion(rdfs:label "cardiac mesenchymal cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + # Class: (parafollicular cell) AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "ISBN:0517223651") "A neuroepithelial cells that occurs singly or in small groups, close to the outer follicular borders but within the follicular basement membrane of the thyroid. Expresses a form of the neural cell adhesion molecule (N-CAM) on their surface. Secretes calcitonin, 5-hydroxytryptamine and dopamine.") @@ -18591,6 +33455,7 @@ AnnotationAssertion(Annotation( "FMA:68653") "parafollicular cell of thyroid gland") AnnotationAssertion(Annotation( "FMA:68653") "thyroid parafollicular cell") AnnotationAssertion(rdfs:label "parafollicular cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) SubClassOf(Annotation( "true") ) SubClassOf( ObjectSomeValuesFrom( )) @@ -18622,7 +33487,6 @@ AnnotationAssertion( "corneal epithelial cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -SubClassOf( ) # Class: (monocyte) @@ -18636,6 +33500,7 @@ AnnotationAssertion( ) AnnotationAssertion(rdfs:comment "Morphology: Mononuclear cell, diameter, 14 to 20 _M, N/C ratio 2:1-1:1. Nucleus may appear in variety of shapes: round, kidney, lobulated, or convoluted. Fine azurophilic granules present; markers: CD11b (shared with other myeloid cells), human: CD14, mouse: F4/80-mid,GR1-low; location: Blood, but can be recruited into tissues; role or process: immune & tissue remodelling; lineage: hematopoietic, myeloid.") AnnotationAssertion(rdfs:label "monocyte") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) SubClassOf( ObjectSomeValuesFrom( )) @@ -18650,6 +33515,15 @@ AnnotationAssertion(rdfs:label "germ SubClassOf(Annotation( "true") ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (odontoclast) + +AnnotationAssertion(Annotation( "GOC:add") "A specialized osteoclast associated with the absorption and removal of cementum.") +AnnotationAssertion( "BTO:0002516") +AnnotationAssertion( "FMA:83027") +AnnotationAssertion(rdfs:label "odontoclast") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) + # Class: (androgen secreting cell) AnnotationAssertion(Annotation( "GOC:tfm") "A steroid hormone secreting cell that secretes androgen.") @@ -18660,7 +33534,7 @@ EquivalentClasses( ObjectIntersection AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:tfm") "An erythrocyte lacking a nucleus.") AnnotationAssertion( "red blood cell") -AnnotationAssertion(Annotation( ) "RBC") +AnnotationAssertion(Annotation( ) "RBC") AnnotationAssertion(rdfs:label "enucleate erythrocyte") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) @@ -18677,6 +33551,7 @@ AnnotationAssertion( "pyramidal cell") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "pyramidal neuron") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (retinal rod cell) @@ -18691,6 +33566,26 @@ AnnotationAssertion(rdfs:label "reti SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (vestibular hair cell) + +AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "MESH:D018069") "A mechanoreceptor located in the acoustic maculae and the semicircular canals that mediates the sense of balance, movement, and head position. The vestibular hair cells are connected to accessory structures in such a way that movements of the head displace their stereocilia. This influences the membrane potential of the cells which relay information about movements via the vestibular part of the vestibulocochlear nerve to the brain stem.") +AnnotationAssertion( "FMA:62351") +AnnotationAssertion( "vestibular receptor cell") +AnnotationAssertion(rdfs:label "vestibular hair cell") +SubClassOf( ) + +# Class: (GABAergic neuron) + +AnnotationAssertion(Annotation( "GOC:tfm") "A neuron that uses GABA as a vesicular neurotransmitter") +AnnotationAssertion( "FBbt:00007228") +AnnotationAssertion( "FMA:84788") +AnnotationAssertion( "MESH:D059330") +AnnotationAssertion( "WBbt:0005190") +AnnotationAssertion( "GABA-ergic neuron") +AnnotationAssertion(rdfs:label "GABAergic neuron") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + # Class: (acinar cell) AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "http://www.copewithcytokines.de") "A secretory cell that is grouped together with other cells of the same type to form grape shaped clusters known as acini (singular acinus).") @@ -18709,6 +33604,7 @@ AnnotationAssertion(Annotation( "doi:10.1038/s41598-018-27692-8") "olfactory bulb granule cell") AnnotationAssertion(Annotation( "doi:10.1038/s41598-018-27692-8") rdfs:comment "Granule cells are the most abundant neuronal population in the olfactory bulb and are continuously renewed throughout life.") AnnotationAssertion(rdfs:label "olfactory granule cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) @@ -18720,7 +33616,7 @@ SubClassOf( ObjectSomeValuesFrom( "TAIR:sr") "A cell involved in transporting nutrients, minerals, water, gases and other chemicals between cells for a variety of purposes including conveying nutrition to other tissues, removing waste products from the tissues, conveying gases for respiration, distributing heat and repelling invasion of foreign substances.") AnnotationAssertion(rdfs:label "transporting cell") -SubClassOf( ) +SubClassOf( ) # Class: (supporting cell) @@ -18728,7 +33624,7 @@ AnnotationAssertion(Annotation( "BTO:0002315") AnnotationAssertion( "supportive cell") AnnotationAssertion(rdfs:label "supporting cell") -SubClassOf( ) +SubClassOf( ) # Class: (hepatic stellate cell) @@ -18771,6 +33667,7 @@ SubClassOf( ObjectSomeValuesFrom( "GOC:tfm") Annotation( "ISBN:0618947256") "A cell that stains readily in the anterior pituitary gland.") AnnotationAssertion( "FMA:83089") AnnotationAssertion(rdfs:label "chromophil cell of anterior pituitary gland") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) @@ -18820,6 +33717,7 @@ AnnotationAssertion( "renin secreting cell") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "kidney granular cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) @@ -18873,8 +33771,33 @@ AnnotationAssertion( ) AnnotationAssertion(rdfs:label "podocyte") AnnotationAssertion(rdfs:seeAlso "https://github.com/obophenotype/cell-ontology/issues/1460") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (primary oocyte) + +AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "ISBN:0721662544") "A primary oocyte is an oocyte that has not completed female meosis I.") +AnnotationAssertion( ) +AnnotationAssertion( "BTO:0000512") +AnnotationAssertion( "FMA:18645") +AnnotationAssertion( "primary oogonium") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "primary oocyte") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (secondary oocyte) + +AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "ISBN:0721662544") "A secondary oocyte is an oocyte that has not completed meiosis II.") +AnnotationAssertion( "BTO:0003094") +AnnotationAssertion( "FMA:18646") +AnnotationAssertion( "primary oogonium") +AnnotationAssertion(rdfs:label "secondary oocyte") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (primary spermatocyte) AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "ISBN:0721662544") "A diploid cell that has derived from a spermatogonium and can subsequently begin meiosis and divide into two haploid secondary spermatocytes.") @@ -18883,8 +33806,6 @@ AnnotationAssertion( "FMA:72292") AnnotationAssertion(rdfs:label "primary spermatocyte") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) # Class: (secondary spermatocyte) @@ -18895,8 +33816,6 @@ AnnotationAssertion( "FMA:72293") AnnotationAssertion(rdfs:label "secondary spermatocyte") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) # Class: (fenestrated cell) @@ -18904,7 +33823,6 @@ SubClassOf( ObjectSomeValuesFrom( "window cell") AnnotationAssertion(rdfs:label "fenestrated cell") SubClassOf( ) -SubClassOf( ) # Class: (collagen secreting cell) @@ -18942,7 +33860,6 @@ AnnotationAssertion(rdfs:label "prim EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) SubClassOf(Annotation( "true") ) -SubClassOf( ) # Class: (female gamete) @@ -18959,12 +33876,14 @@ AnnotationAssertion( "WBbt:0006829") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "glutamatergic neuron") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) # Class: (muscle precursor cell) AnnotationAssertion(Annotation( "GOC:add") "A non-terminally differentiated cell that is capable of developing into a muscle cell.") AnnotationAssertion(rdfs:label "muscle precursor cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) @@ -18978,6 +33897,12 @@ AnnotationAssertion(rdfs:label "radi SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (stellate interneuron) + +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "stellate interneuron") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (PP cell) AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "JB:jb") Annotation( "PMID:15153415") "A cell that stores and secretes pancreatic polypeptide hormone.") @@ -18998,6 +33923,7 @@ AnnotationAssertion( "WBbt:0006746") AnnotationAssertion( "dopaminergic cell") AnnotationAssertion(rdfs:label "dopaminergic neuron") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) @@ -19011,10 +33937,12 @@ SubClassOf( (choroid plexus epithelial cell) AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:tfm") Annotation( "JB:jb") Annotation( "PMID:9550134") "Specialized ependymal cell that produces the cerebrospinal fluid from the blood and secretes it into the lumen of the brain and spinal chord.") +AnnotationAssertion( ) AnnotationAssertion( "2023-08-04T08:48:30Z"^^xsd:dateTime) AnnotationAssertion(Annotation( "DOI:10.1101/2022.10.12.511898") "choroid plexus cell") AnnotationAssertion( "FMA:70549") AnnotationAssertion( "epithelial cell of choroid plexus") +AnnotationAssertion( ) AnnotationAssertion(rdfs:label "choroid plexus epithelial cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) @@ -19036,11 +33964,13 @@ AnnotationAssertion( "FMA:70557") AnnotationAssertion(rdfs:comment "The term \"neuroepithelial cell\" is used to describe both this cell type and sensory epithelial cell (CL:0000098).") AnnotationAssertion(rdfs:label "neurecto-epithelial cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) # Class: (stratum granulosum cell) AnnotationAssertion(rdfs:label "stratum granulosum cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) @@ -19052,8 +33982,6 @@ AnnotationAssertion( "MESH:D053687") AnnotationAssertion(rdfs:label "somatic stem cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) # Class: (urothelial cell) @@ -19062,7 +33990,6 @@ AnnotationAssertion( "urinary tract transitional epithelial cell") AnnotationAssertion(rdfs:label "urothelial cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) # Class: (striated muscle cell) @@ -19071,6 +33998,7 @@ AnnotationAssertion( "CALOHA:TS-2157") AnnotationAssertion( "FMA:86936") AnnotationAssertion(rdfs:label "striated muscle cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf( ) DisjointClasses( ) @@ -19088,6 +34016,7 @@ AnnotationAssertion( "immune cell") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "leukocyte") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) @@ -19102,8 +34031,8 @@ AnnotationAssertion( "MESH:D012165") AnnotationAssertion( "gangliocyte") AnnotationAssertion( "ganglion cell of retina") -AnnotationAssertion(Annotation( "doi:10.1038/s41598-020-66092-9") Annotation( ) "RGC") -AnnotationAssertion(Annotation( "doi:10.1038/s41598-020-66092-9") Annotation( ) Annotation( ) "RGCs") +AnnotationAssertion(Annotation( "doi:10.1038/s41598-020-66092-9") Annotation( ) "RGC") +AnnotationAssertion(Annotation( "doi:10.1038/s41598-020-66092-9") Annotation( ) Annotation( ) "RGCs") AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "retinal ganglion cell") @@ -19116,8 +34045,8 @@ AnnotationAssertion(Annotation( ) AnnotationAssertion( "BTO:0004120") AnnotationAssertion( "horizontal cell") -AnnotationAssertion(Annotation( "doi:10.1038/s41598-020-66092-9") Annotation( ) "HC") -AnnotationAssertion(Annotation( "doi:10.1038/s41598-020-66092-9") Annotation( ) Annotation( ) "HCs") +AnnotationAssertion(Annotation( "doi:10.1038/s41598-020-66092-9") Annotation( ) "HC") +AnnotationAssertion(Annotation( "doi:10.1038/s41598-020-66092-9") Annotation( ) Annotation( ) "HCs") AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "retina horizontal cell") @@ -19142,22 +34071,41 @@ AnnotationAssertion( ) AnnotationAssertion(rdfs:comment "This class encompasses the muscle cells responsible for heart* contraction in both vertebrates and arthropods. The ultrastucture of a wide range of arthropod heart cells has been examined including spiders, horseshoe crabs, crustaceans (see Sherman, 1973 and refs therein) and insects (see Lehmacher et al (2012) and refs therein). According to these refs, the cells participating in heart contraction in all cases are transversely striated. Insects hearts additionally contain ostial cells, also transversely striated muscle cells, but which do not participate in heart contraction.") AnnotationAssertion(rdfs:label "cardiac muscle cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf( ObjectSomeValuesFrom( )) # Class: (retinal bipolar neuron) AnnotationAssertion(Annotation( "PMID:14689473") "A bipolar neuron found in the retina and having connections with photoreceptors cells and neurons in the inner plexiform layer.") AnnotationAssertion( ) -AnnotationAssertion(Annotation( "doi:10.1038/s41598-020-66092-9") Annotation( ) "BC") -AnnotationAssertion(Annotation( "doi:10.1038/s41598-020-66092-9") Annotation( ) Annotation( ) "BCs") -AnnotationAssertion(Annotation( "GSE137537") Annotation( ) Annotation( ) "BPs") +AnnotationAssertion(Annotation( "doi:10.1038/s41598-020-66092-9") Annotation( ) "BC") +AnnotationAssertion(Annotation( "doi:10.1038/s41598-020-66092-9") Annotation( ) Annotation( ) "BCs") +AnnotationAssertion(Annotation( "GSE137537") Annotation( ) Annotation( ) "BPs") AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "retinal bipolar neuron") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( )))) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (cone retinal bipolar cell) + +AnnotationAssertion(Annotation( "PMID:14689473") "A bipolar neuron found in the retina and having connections with cone photoreceptor cells and neurons in the inner plexiform layer.") +AnnotationAssertion(rdfs:label "cone retinal bipolar cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (nucleated thrombocyte) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:tfm") Annotation( "PMID:16360205") "A nucleated blood cell involved in coagulation, typically seen in birds and other non-mammalian vertebrates.") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:comment "Note that this is a non-mammalian cell type. Use platelet ; CL:0000233 for thrombocytes (platelets) in mammals.") +AnnotationAssertion(rdfs:label "nucleated thrombocyte") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (myeloid cell) AnnotationAssertion(Annotation( "GOC:add") "A cell of the monocyte, granulocyte, mast cell, megakaryocyte, or erythroid lineage.") @@ -19165,6 +34113,7 @@ AnnotationAssertion( "CALOHA:TS-0647") AnnotationAssertion( "MESH:D022423") AnnotationAssertion(rdfs:label "myeloid cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) # Class: (erythroid lineage cell) @@ -19190,6 +34139,7 @@ AnnotationAssertion( "normoblast") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "erythroblast") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) SubClassOf( ObjectSomeValuesFrom( )) @@ -19197,6 +34147,7 @@ SubClassOf( ObjectSomeValuesFrom( "GOC:add") "A cell of the monocyte, granulocyte, or mast cell lineage.") AnnotationAssertion(rdfs:label "myeloid leukocyte") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) # Class: (neutrophil) @@ -19273,13 +34224,11 @@ SubClassOf(Annotation( # Class: (myeloid dendritic cell) AnnotationAssertion(Annotation( "GOC:add") Annotation( "PMID:10449155") Annotation( "PMID:17332250") Annotation( "PMID:9521319") "A dendritic cell of the myeloid lineage.") -AnnotationAssertion( ) AnnotationAssertion( "interdigitating cell") AnnotationAssertion( "veiled cell") AnnotationAssertion( "BTO:0004721") AnnotationAssertion( "CD11c+CD123- DC") AnnotationAssertion( "mDC") -AnnotationAssertion( ) AnnotationAssertion(rdfs:comment "These cells are CD1a-negative, CD1b-positive, CD11a-positive, CD11c-positive, CD13-positive, CD14-negative, CD20-negative, CD21-negative, CD33-positive, CD40-negative, CD50-positive, CD54-positive, CD58-positive, CD68-negative, CD80-negative, CD83-negative, CD85j-positive, CD86-positive, CD89-negative, CD95-positive, CD120a-negative, CD120b-positive, CD123-negative, CD178-negative, CD206-negative, CD207-negative, CD209-negative, and TNF-alpha-negative. Upon TLR stimulation, they are capable of producing high levels of TNF-alpha, IL-6, CXCL8 (IL-8).") AnnotationAssertion(rdfs:label "myeloid dendritic cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) @@ -19293,12 +34242,47 @@ AnnotationAssertion( "mature B-lymphocyte") AnnotationAssertion(rdfs:comment "Mature B cells are also reportedly CD10-negative, CD19-positive, CD22-positive, CD34-negative, CD48-positive, CD79a-positive, CD84-positive, CD127-negative, CD352-positive, RAG-negative, TdT-negative, Vpre-B-negative, and pre-BCR-negative. Transcription factors expressed: Pax5-positive.") AnnotationAssertion(rdfs:label "mature B cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) SubClassOf( ObjectSomeValuesFrom( )) DisjointClasses( ) DisjointClasses( ) DisjointClasses( ) +# Class: (plasma cell) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:dsd") Annotation( "GO_REF:0000031") Annotation( "ISBN:0721601464") Annotation( "ISBN:0781735149") Annotation( "PMID:19447676") Annotation( "PMID:20081059") Annotation( "PMID:20839338") Annotation( "PMID:20951740") Annotation( "http://en.wikipedia.org/wiki/Plasma_cell") "A terminally differentiated, post-mitotic, antibody secreting cell of the B cell lineage with the phenotype CD138-positive, surface immunonoglobulin-negative, and MHC Class II-negative. Plasma cells are oval or round with extensive rough endoplasmic reticulum, a well-developed Golgi apparatus, and a round nucleus having a characteristic cartwheel heterochromatin pattern and are devoted to producing large amounts of immunoglobulin.") +AnnotationAssertion( ) +AnnotationAssertion( "BTO:0000392") +AnnotationAssertion( "FMA:70574") +AnnotationAssertion( "MESH:D010950") +AnnotationAssertion( "plasma B cell") +AnnotationAssertion( "plasma B-cell") +AnnotationAssertion( "plasmacyte") +AnnotationAssertion( "plasmocyte") +AnnotationAssertion( "effector B cell") +AnnotationAssertion( "effector B-cell") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:comment "Plasma cells develop in the spleen and migrate to the bone marrow. Plasma cells are also reportedly CD5-negative, CD10-negative, CD19-positive, CD20-negative, CD21-negative, CD22-negative, CD23-negative, CD24-negative, CD25-negative, CD27-positive, CD34-negative, CD38-positive, CD40-positive, CD43-positive, CD45-positive, CD48-positive, CD53-low, CD80-negative, CD81-positive, CD86-positive, CD95-positive, CD196-negative, CD229-positive, CD270-positive, CD352-positive, CD361-positive, and IgD-negative. Transcription factors: BLIMP1-positive, IRF4-positive, PAX5-negative, SpiB-negative, Ets1-negative, and XBP1-positive.") +AnnotationAssertion(rdfs:label "plasma cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (memory B cell) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:dsd") Annotation( "GOC:rhs") Annotation( "GO_REF:0000031") Annotation( "ISBN:0781735149") Annotation( "PMID:20081059") Annotation( "PMID:20839338") Annotation( "http://en.wikipedia.org/wiki/Memory_B_cell") "A memory B cell is a mature B cell that is long-lived, readily activated upon re-encounter of its antigenic determinant, and has been selected for expression of higher affinity immunoglobulin. This cell type has the phenotype CD19-positive, CD20-positive, MHC Class II-positive, and CD138-negative.") +AnnotationAssertion( ) +AnnotationAssertion( "memory B lymphocyte") +AnnotationAssertion( "memory B-cell") +AnnotationAssertion( "memory B-lymphocyte") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:comment "Memory B-cells are also reportedly CD5-negative, CD10-negative, CD21-positive, CD22-positive, CD23-negative, CD24-positive, CD25-positive, CD27-positive, CD34-negative, CD38-negative, CD40-positive, CD43-negative, CD44-positive, CD45-positive, CD53-positive, CD80-negative, CD81-negative, CD86-positive, and CD196/CCR6-positive.") +AnnotationAssertion(rdfs:label "memory B cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) + # Class: (naive B cell) AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:dsd") Annotation( "GOC:rhs") Annotation( "GO_REF:0000031") Annotation( "ISBN:0781765196") Annotation( "PMID:19447676") Annotation( "PMID:20081059") Annotation( "PMID:20839338") Annotation( "PMID:20933013") Annotation( "PMID:22343568") "A naive B cell is a mature B cell that has the phenotype surface IgD-positive, surface IgM-positive, CD20-positive, CD27-negative and that has not yet been activated by antigen in the periphery.") @@ -19309,6 +34293,7 @@ AnnotationAssertion( ) AnnotationAssertion(rdfs:comment "This cell type is compatible with the HIPC Lyoplate markers for 'naive B cell'. Per DSD: Naive B cells are also reportedly CD10-negative, CD19-positive, CD20-positive, CD21-positive, CD22-positive, CD25-negative, CD27-negative, CD34-negative, CD40-positive, CD43-negative, CD45-positive, CD48-positive, CD53-positive, CD80-negative, CD81-positive, CD84-positive, CD86-negative, CD95-negative, CD138-negative, CD150-positive, CD184/CXCR4-positive, CD185/CXCR5-positive, CD196/CCR6-positive, CD200-positive, CD229-positive, CD243-positive, CD289-positive, CD290-positive, CD352-positive, MHCII/HLA-DR-positive, cadherin 9-positive, and sIgH-positive, Transcription factors: Pax5-positive, ETS1-positive, FOXO1A-positive, KLF4-positive, KLF9-positive, MiTF-positive, OBF1-positive, PLZF-positive, and SpiB-positive.") AnnotationAssertion(rdfs:label "naive B cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) SubClassOf( ObjectSomeValuesFrom( )) @@ -19324,6 +34309,7 @@ AnnotationAssertion( ) AnnotationAssertion(rdfs:comment "Immature B cells are also reportedly CD5-positive, CD10-positive, CD19-positive, CD20-positive, CD21-positive, CD22-positive, CD24-positive, CD25-negative, CD27-negative, CD34-negative, CD38-positive, CD40-positive, CD43-negative, CD45-positive, CD48-positive, CD53-positive, CD79a-positive, CD80-negative, CD81-positive, CD86-negative, CD95-negative, CD127-negative, CD138-negative, CD185-positive, CD196-positive, MHCII/HLA-DR-positive, RAG-positive, TdT-negative, Vpre-B-negative, and preBCR-negative. Transcription factors expressed: Pax5-positive.") AnnotationAssertion(rdfs:label "immature B cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) @@ -19336,6 +34322,7 @@ AnnotationAssertion( "pre-B cell") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "precursor B cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) DisjointClasses( ) @@ -19353,9 +34340,27 @@ AnnotationAssertion( ) AnnotationAssertion(rdfs:comment "This cell type is compatible with the HIPC Lyoplate markers for 'transitional B cell'.") AnnotationAssertion(rdfs:label "transitional stage B cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (B-2 B cell) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:dsd") Annotation( "GOC:tfm") Annotation( "ISBN:0781735149") Annotation( "PMID:11861604") Annotation( "PMID:20933013") "A conventional B cell subject to antigenic stimulation and dependent on T cell help and with a distinct surface marker expression pattern from B-1 B cells. These cells are CD43-negative.") +AnnotationAssertion( "B-2 B lymphocyte") +AnnotationAssertion( "B-2 B-cell") +AnnotationAssertion( "B-2 B-lymphocyte") +AnnotationAssertion( "B2 B cell") +AnnotationAssertion( "B2 B lymphocyte") +AnnotationAssertion( "B2 B-cell") +AnnotationAssertion( "B2 B-lymphocyte") +AnnotationAssertion( "B2 cell") +AnnotationAssertion( "B-0 B cell") +AnnotationAssertion(rdfs:comment "B-2 B cells are reportedly CD48-positive, CD244-negative, and CD352-positive.") +AnnotationAssertion(rdfs:label "B-2 B cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) + # Class: (pro-B cell) AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:dsd") Annotation( "ISBN:0781735149") Annotation( "PMID:12633665") Annotation( "PMID:16551251") Annotation( "PMID:18432934") "A progenitor cell of the B cell lineage, with some lineage specific activity such as early stages of recombination of B cell receptor genes, but not yet fully committed to the B cell lineage until the expression of PAX5 occurs.") @@ -19373,6 +34378,7 @@ AnnotationAssertion(Annotation( ) AnnotationAssertion(rdfs:comment "Human pro-B cells are reportedly CD10-positive, CD22-positive, CD34-positive, CD38-positive, CD45-low, CD48-positive, CD79a-positive, CD127-positive, CD184-positive, RAG-positive, TdT-positive, Vpre-B-positive, pre-BCR-negative, IgD-negative, and IgM-negative. Transcription factors expressed: Pax5-positive, EBF-positive, E2A-negative, Ikaros-negative, and PU.1-negative.") AnnotationAssertion(rdfs:label "pro-B cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) SubClassOf( ObjectSomeValuesFrom( )) @@ -19385,9 +34391,38 @@ AnnotationAssertion( "DN1 thymocyte") AnnotationAssertion( "TN1 cell") AnnotationAssertion(rdfs:label "pro-T cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (thromboblast) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:tfm") Annotation( "PMID:7758949") "A progenitor cell of the thrombocyte, a nucleated blood cell involved in coagulation typically seen in birds and other non-mammalian vertebrates.") +AnnotationAssertion(rdfs:comment "Note that this is a non-mammalian cell type.") +AnnotationAssertion(rdfs:label "thromboblast") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (neutrophil progenitor cell) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:tfm") Annotation( "ISBN:0721601464") "A progenitor cell of the neutrophil lineage.") +AnnotationAssertion( "neutrophil stem cell") +AnnotationAssertion(rdfs:label "neutrophil progenitor cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (myeloblast) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0721601464") Annotation( "http://en.wikipedia.org/wiki/Myeloblast") Annotation( "http://www.cap.org") "The most primitive precursor in the granulocytic series, having fine, evenly distributed chromatin, several nucleoli, a high nuclear-to-cytoplasmic ration (5:1-7:1), and a nongranular basophilic cytoplasm. They reside in the bone marrow.") +AnnotationAssertion( "BTO:0000187") +AnnotationAssertion( "FMA:83524") +AnnotationAssertion(rdfs:label "myeloblast") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (hematopoietic multipotent progenitor cell) AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:tfm") Annotation( "PMID:19022770") "A hematopoietic multipotent progenitor cell is multipotent, but not capable of long-term self-renewal. These cells are characterized as lacking lineage cell surface markers and being CD34-positive in both mice and humans.") @@ -19400,6 +34435,7 @@ AnnotationAssertion( ) AnnotationAssertion(rdfs:comment "Markers differ between mouse and human.") AnnotationAssertion(rdfs:label "hematopoietic multipotent progenitor cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) @@ -19414,6 +34450,7 @@ AnnotationAssertion( "FMA:70338") AnnotationAssertion(rdfs:comment "Note that this is a class of cell types, not an identified single cell type.") AnnotationAssertion(rdfs:label "lymphoid lineage restricted progenitor cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) DisjointClasses( ) @@ -19426,8 +34463,81 @@ AnnotationAssertion( "FMA:70339") AnnotationAssertion(rdfs:comment "Note that this is a class of cell types, not an identified single cell type.") AnnotationAssertion(rdfs:label "myeloid lineage restricted progenitor cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) +# Class: (mononuclear cell) + +AnnotationAssertion(Annotation( "GOC:add") "A leukocyte with a single non-segmented nucleus in the mature form.") +AnnotationAssertion( "BTO:0000878") +AnnotationAssertion( "CALOHA:TS-0768") +AnnotationAssertion( "FMA:86713") +AnnotationAssertion( "mononuclear leukocyte") +AnnotationAssertion( "peripheral blood mononuclear cell") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "mononuclear cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) + +# Class: (follicular B cell) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:dsd") Annotation( "ISBN:0781735149") Annotation( "PMCID:PMC2193793") Annotation( "PMID:20933013") Annotation( "http://en.wikipedia.org/wiki/Follicular_B_Cells") "A resting mature B cell that has the phenotype IgM-positive, IgD-positive, CD23-positive and CD21-positive, and found in the B cell follicles of the white pulp of the spleen or the corticol areas of the peripheral lymph nodes. This cell type is also described as being CD19-positive, B220-positive, AA4-negative, CD43-negative, and CD5-negative.") +AnnotationAssertion( "Fo B cell") +AnnotationAssertion( "Fo B-cell") +AnnotationAssertion( "follicular B lymphocyte") +AnnotationAssertion( "follicular B-cell") +AnnotationAssertion( "follicular B-lymphocyte") +AnnotationAssertion(rdfs:comment "Follicular B cells are also reportedly CD48-positive, CD84-positive, CD229-positive, and CD352-positive.") +AnnotationAssertion(rdfs:label "follicular B cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) + +# Class: (germinal center B cell) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:dsd") Annotation( "GOC:tfm") Annotation( "ISBN:0781735149") Annotation( "PMID:19447676") Annotation( "PMID:20933013") "A rapidly cycling mature B cell that has distinct phenotypic characteristics and is involved in T-dependent immune responses and located typically in the germinal centers of lymph nodes. This cell type expresses Ly77 after activation.") +AnnotationAssertion( ) +AnnotationAssertion( "GC B cell") +AnnotationAssertion( "GC B lymphocyte") +AnnotationAssertion( "GC B-cell") +AnnotationAssertion( "GC B-lymphocyte") +AnnotationAssertion( "germinal center B lymphocyte") +AnnotationAssertion( "germinal center B-cell") +AnnotationAssertion( "germinal center B-lymphocyte") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:comment "Germinal center B cells are also reportedly CD10-positive, CD19-positive, CD20-positive, CD38-positive, CD44-low, CD45-positive, CD48-positive, CD95-positive, CD352-positive, and HLA-DR-positive. Transcription factors: BCL6-positive, Ets1-positive, IRF8-positive, MTA3-positive, OBF1-positive, PAX5-positive, SpiB-positive, and STAT3-positive.") +AnnotationAssertion(rdfs:label "germinal center B cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (marginal zone B cell of spleen) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:dsd") Annotation( "ISBN:0781735149") Annotation( "PMID:10933592") Annotation( "PMID:20933013") Annotation( "http://en.wikipedia.org/wiki/Marginal-zone_B_cell") "A mature B cell that is located in the marginal zone of the spleen with the phenotype CD23-negative and CD21-positive and expressing a B cell receptor usually reactive to bacterial cell wall components or senescent self components such as oxidized-LDL. This cell type is also described as being CD19-positive, B220-positive, IgM-high, AA4-negative, CD35-high.") +AnnotationAssertion( ) +AnnotationAssertion( "MZ B cell") +AnnotationAssertion( "MZ B lymphocyte") +AnnotationAssertion( "MZ B-cell") +AnnotationAssertion( "MZ B-lymphocyte") +AnnotationAssertion( "marginal zone B cell") +AnnotationAssertion( "marginal zone B lymphocyte") +AnnotationAssertion( "marginal zone B-cell") +AnnotationAssertion( "marginal zone B-lymphocyte") +AnnotationAssertion( "B cell of marginal zone of spleen") +AnnotationAssertion( "marginal zone of spleen B cell") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:comment "MZ B cells are reportedly CD1-positive (mice), CD20-positive, CD48-positive, CD84-positive, CD150-positive, CD229-positive, and CD352-positive.") +AnnotationAssertion(rdfs:label "marginal zone B cell of spleen") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) + +# Class: (ciliated olfactory receptor neuron) + +AnnotationAssertion(Annotation( "PMID:16841163") "An olfactory receptor cell in which the apical ending of the dendrite is a pronounced ciliated olfactory knob.") +AnnotationAssertion( "ciliated olfactory sensory neuron") +AnnotationAssertion( "ciliated sensory neuron") +AnnotationAssertion(rdfs:label "ciliated olfactory receptor neuron") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (microvillous olfactory receptor neuron) AnnotationAssertion(Annotation( "PMID:16841163") "An olfactory receptor cell in which the apical ending of the dendrite is a knob that bears numerous microvilli.") @@ -19436,6 +34546,19 @@ AnnotationAssertion( "microvillous olfactory receptor neuron") SubClassOf( ) +# Class: (serotonergic neuron) + +AnnotationAssertion(Annotation( "SANBI:mhl") "A neuron that releases serotonin as a neurotransmitter.") +AnnotationAssertion( "FBbt:00005133") +AnnotationAssertion( "MESH:D059326") +AnnotationAssertion( "WBbt:0006837") +AnnotationAssertion( "5-HT neuron") +AnnotationAssertion( "5-hydroxytryptamine neuron") +AnnotationAssertion( "serotinergic neuron") +AnnotationAssertion(rdfs:label "serotonergic neuron") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + # Class: (olfactory epithelial supporting cell) AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "ISBN:0517223651") Annotation( "SANBI:mhl") "Olfactory epithelial support cell is a columnar cell that extends from the epithelial free margin to the basement membrane of the olfactory epithelium. This cell type has a large, vertically, elongate, euchromatic nucleus, along with other nuclei, forms a layer superficial to the cell body of the receptor cell; sends long somewhat irregular microvilli into the mucus layer; at the base, with expanded end-feet containing numerous lamellated dense bodies resembling lipofuscin of neurons.") @@ -19445,6 +34568,7 @@ AnnotationAssertion( "supporting cell of olfactory epithelium") AnnotationAssertion( "sustentaculocyte of olfactory epithelium") AnnotationAssertion(rdfs:label "olfactory epithelial supporting cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) @@ -19460,6 +34584,7 @@ SubClassOf( "SANBI:mhl") "Neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface.") AnnotationAssertion(rdfs:label "neuromast hair cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) # Class: (slow muscle myoblast) @@ -19467,14 +34592,12 @@ SubClassOf( "SANBI:mhl") "A skeletal muscle myoblast that differentiates into slow muscle fibers.") AnnotationAssertion(rdfs:label "slow muscle myoblast") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) # Class: (fast muscle myoblast) AnnotationAssertion(Annotation( "SANBI:mhl") "A skeletal muscle myoblast that differentiates into fast muscle fibers.") AnnotationAssertion(rdfs:label "fast muscle myoblast") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) # Class: (classical monocyte) @@ -19497,6 +34620,7 @@ AnnotationAssertion( "resting histiocyte") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "tissue-resident macrophage") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) # Class: (central nervous system macrophage) @@ -19504,6 +34628,7 @@ SubClassOf(Annotation( AnnotationAssertion(Annotation( "GO_REF:0000031") Annotation( "PMID:16322748") "A tissue-resident macrophage found in the central nervous system.") AnnotationAssertion( "CNS macrophage") AnnotationAssertion(rdfs:label "central nervous system macrophage") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) # Class: (perivascular macrophage) @@ -19511,9 +34636,19 @@ SubClassOf(Annotation( AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "GO_REF:0000031") Annotation( "PMID:16507898") "A central nervous system macrophage found in small blood vessels in the brain. Markers include CD14+CD16+CD163+.") AnnotationAssertion(rdfs:comment "Markers: Human/monkey, mice: CD163. Human: CD14+CD16+CD163+.") AnnotationAssertion(rdfs:label "perivascular macrophage") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) SubClassOf( ) +# Class: (myeloid suppressor cell) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:ana") Annotation( "GO_REF:0000031") Annotation( "PMID:16168663") Annotation( "PMID:17016554") Annotation( "PMID:17016559") "An immature myeloid leukocyte of heterogeneous phenotype found particularly in cancer and sepsis patients that is capable of suppressing activity of T cells in ex vivo assays. This cell type is CD45-positive, CD11b-positive.") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:comment "Markers: Mouse: CD11b+GR1+CD31+; Human: CD34+ CD33+CD15-CD13+. (According to some reports in humans these cells are iNOS+ARG1+IL13+IFNg+); location: In cancerous tissue; in the blood and lymphoid organs in sepsis.") +AnnotationAssertion(rdfs:label "myeloid suppressor cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) + # Class: (thymocyte) AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:tfm") Annotation( "GO_REF:0000031") Annotation( "PMID:12415312") "An immature T cell located in the thymus.") @@ -19528,6 +34663,7 @@ AnnotationAssertion( "XAO:0003159") AnnotationAssertion( "thymic lymphocyte") AnnotationAssertion(rdfs:label "thymocyte") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) # Class: (DN1 thymic pro-T cell) @@ -19548,10 +34684,12 @@ SubClassOf( ObjectSomeValuesFrom( (early lymphoid progenitor) AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:dsd") Annotation( "GOC:pam") Annotation( "GOC:tfm") Annotation( "GO_REF:0000031") Annotation( "PMID:19022770") "A lymphoid progenitor cell that is found in bone marrow, gives rise to B cells, T cells, natural killer cells and dendritic cells, and has the phenotype Lin-negative, Kit-positive, Sca-1-positive, FLT3-positive, CD34-positive, CD150 negative, and GlyA-negative.") +AnnotationAssertion( ) AnnotationAssertion( "lymphoid-primed multipotent progenitor") -AnnotationAssertion(Annotation( ) "ELP") -AnnotationAssertion(Annotation( "PMID:18371378") Annotation( ) "GMLP") -AnnotationAssertion(Annotation( ) "LMPP") +AnnotationAssertion(Annotation( ) "ELP") +AnnotationAssertion(Annotation( "PMID:18371378") Annotation( ) "GMLP") +AnnotationAssertion(Annotation( ) "LMPP") +AnnotationAssertion( ) AnnotationAssertion(rdfs:comment "Markers are associated with mouse cells. ELP transcription factors include E2A-positive, Ikaros-positive, EBF-negative, Pax5-negative, PU.1-negative.") AnnotationAssertion(rdfs:label "early lymphoid progenitor") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) @@ -19577,12 +34715,48 @@ AnnotationAssertion(rdfs:label "lymp SubClassOf(Annotation( "true") ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (antibody secreting cell) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:tfm") Annotation( "GO_REF:0000031") Annotation( "ISBN:0721601464") Annotation( "ISBN:0781735149") "A lymphocyte of B lineage that is devoted to secreting large amounts of immunoglobulin.") +AnnotationAssertion(rdfs:label "antibody secreting cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) + +# Class: (IgE memory B cell) + +AnnotationAssertion(Annotation( "GOC:rhs") Annotation( "GO_REF:0000031") Annotation( "ISBN:0781765196") "A class switched memory B cell that expresses IgE on the cell surface.") +AnnotationAssertion( "IgE memory B lymphocyte") +AnnotationAssertion( "IgE memory B-cell") +AnnotationAssertion( "IgE memory B-lymphocyte") +AnnotationAssertion( "memory IgE B cell") +AnnotationAssertion( "memory IgE B lymphocyte") +AnnotationAssertion( "memory IgE B-cell") +AnnotationAssertion( "memory IgE B-lymphocyte") +AnnotationAssertion(rdfs:label "IgE memory B cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) + +# Class: (preBCR-positive large pre-B-II cell) + +AnnotationAssertion(Annotation( "GOC:rhs") Annotation( "GOC:tfm") Annotation( "GO_REF:0000031") Annotation( "PMID:9785673") "An preBRC-positive large pre-B-II cell is a large pre-B-II cell that is pre-B cell receptor-positive, composed of surrogate light chain protein (SL), which is composed of VpreB , Lambda 5/14.1, in complex with immunoglobulin mu heavy chain (IgHmu) on the cell surface.") +AnnotationAssertion(rdfs:label "preBCR-positive large pre-B-II cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) + +# Class: (preBCR-negative large pre-B-II cell) + +AnnotationAssertion(Annotation( "GOC:rhs") Annotation( "GOC:tfm") Annotation( "GO_REF:0000031") Annotation( "PMID:9785673") "A pre-BCR-negative large pre-B-II cell is a large pre-B-II cell that is pre-B cell receptor-negative, composed of surrogate light chain protein (SL), which is composed of VpreB and Lambda 5/14.1, in complex with immunoglobulin mu heavy chain (IgHmu), on the cell surface, and lack a DNA rearrangement of immunoglobulin light chain genes.") +AnnotationAssertion(rdfs:label "preBCR-negative large pre-B-II cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) + # Class: (small pre-B-II cell) AnnotationAssertion(Annotation( "GOC:dsd") Annotation( "GOC:rhs") Annotation( "GOC:tfm") Annotation( "GO_REF:0000031") Annotation( "PMID:16551251") Annotation( "PMID:18432934") Annotation( "PMID:9785673") "A small pre-B-II cell is a pre-B-II cell that is Rag1-positive, Rag2-positive, pre-BCR-negative, and BCR-negative, is not proliferating, and carries a DNA rearrangement of one or more immunoglobulin light chain genes.") AnnotationAssertion( "small pre-BII cell") AnnotationAssertion(rdfs:comment "Small pre-B-II cells are also reportedly CD10-positive, CD19-positive, CD34-negative, CD79a-positive, CD127-negative, TdT-negative, Vpre-B-negative, sIgM-negative, and sIgD-negative. Transcription factors: PU.1-positive, Ikaros-positive, E2A-positive, and PAX5-positive.") AnnotationAssertion(rdfs:label "small pre-B-II cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) # Class: (pre-B-II cell) @@ -19594,8 +34768,220 @@ AnnotationAssertion( "pre-BII cell") AnnotationAssertion(rdfs:comment "pre-B-II cell are also reportedly CD19-positive, CD22-positive, CD38-positive, CD45-positive, and CD48-positive.") AnnotationAssertion(rdfs:label "pre-B-II cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) SubClassOf( ObjectSomeValuesFrom( )) +DisjointClasses( ) + +# Class: (pre-B-I cell) + +AnnotationAssertion(Annotation( "GOC:dsd") Annotation( "GOC:rhs") Annotation( "GOC:tfm") Annotation( "GO_REF:0000031") Annotation( "PMID:16551251") Annotation( "PMID:18432934") Annotation( "PMID:20839338") Annotation( "PMID:9785673") "A pre-B-I cell is a precursor B cell that expresses CD34 and surrogate immunoglobulin light chain (VpreB , Lambda 5 (mouse)/14.1 (human)) on the cell surface, and TdT, Rag1,and Rag2 intracellularly. Cell type carries a D-JH DNA rearrangement, and lacks expression of immunglobulin heavy chain protein.") +AnnotationAssertion( "pre-BI cell") +AnnotationAssertion(Annotation( "PMID:11244048") "pro-B cell (Philadelphia nomenclature)") +AnnotationAssertion(rdfs:comment "Human pre-B-I cells are reportedly CD10-positive, CD19-positive, CD22-positive, CD38-positive, CD45-low, CD79a-positive, CD127-negative, pre-BCR-negative, IgM-negative, IgD-negative, and Tdt-positive. Transcription factors expressed: Pax5-positive.") +AnnotationAssertion(rdfs:label "pre-B-I cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (large pre-B-II cell) + +AnnotationAssertion(Annotation( "GOC:dsd") Annotation( "GOC:rhs") Annotation( "GO_REF:0000031") Annotation( "PMID:16551251") Annotation( "PMID:18432934") Annotation( "PMID:9785673") "A large pre-B-II cell is a pre-B-II cell that is proliferating and is Rag1-negative and Rag2-negative.") +AnnotationAssertion(Annotation( "PMID:11244048") "large pre-B cell") +AnnotationAssertion( "large pre-BII cell") +AnnotationAssertion(rdfs:comment "Large pre-B-II cells are also reportedly CD10-positive, CD19-positive, CD34-negative, CD79a-positive, CD127-negative, TdT-negative, Vpre-B-positive, pre-BCR-positive, sIgM-negative, and sIgD-negative. Transcription factors: PU.1-positive, Ikaros-positive, E2A-positive, and PAX5-positive.") +AnnotationAssertion(rdfs:label "large pre-B-II cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) + +# Class: (Bm1 B cell) + +AnnotationAssertion(Annotation( "GOC:dsd") Annotation( "GOC:msz") Annotation( "GO_REF:0000031") Annotation( "PMID:17992590") Annotation( "PMID:18432934") Annotation( "PMID:8006591") "A follicular B cell that is IgD-positive, CD23-negative, and CD38-negative. This naive cell type is activated in the extrafollicular areas through interaction with interdigitating dendritic cells and antigen-specific CD4-positive T cells.") +AnnotationAssertion( "Bm1 B lymphocyte") +AnnotationAssertion( "Bm1 B-cell") +AnnotationAssertion( "Bm1 B-lymphocyte") +AnnotationAssertion(rdfs:comment "These cells are also reportedly CD10-negative, CD39-positive, CD44-positive, CD71-negative, CD77-negative, IgM-positive, IgG-negative, IgA-negative, and IgE-negative.") +AnnotationAssertion(rdfs:label "Bm1 B cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (Bm2 B cell) + +AnnotationAssertion(Annotation( "GOC:dsd") Annotation( "GOC:msz") Annotation( "GO_REF:0000031") Annotation( "PMID:17992590") Annotation( "PMID:18432934") Annotation( "PMID:8006591") "A follicular B cell that is IgD-positive and CD23-positive and CD38-positive. This naive cell type is activated in the extrafollicular areas via interaction with dendritic cells and antigen specific T cells.") +AnnotationAssertion( "Bm2 B lymphocyte") +AnnotationAssertion( "Bm2 B-cell") +AnnotationAssertion( "Bm2 B-lymphocyte") +AnnotationAssertion(rdfs:comment "These cells are also CD10-negative, CD39-positive, CD44-positive, CD71-negative, CD77-negative, IgM-positive, IgG-negative, IgA-negative, and IgE-negative.") +AnnotationAssertion(rdfs:label "Bm2 B cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (Bm3-delta B cell) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:msz") Annotation( "GOC:tfm") Annotation( "GO_REF:0000031") Annotation( "PMID:9280752") "A germinal center B cell that develops from a Bm3 B cell. This cell has the phenotype IgM-negative, IgD-positive, and CD38-positive.") +AnnotationAssertion( "Bm3-delta B lymphocyte") +AnnotationAssertion( "Bm3-delta B-cell") +AnnotationAssertion( "Bm3-delta B-lymphocyte") +AnnotationAssertion(rdfs:label "Bm3-delta B cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (Bm2' B cell) + +AnnotationAssertion(Annotation( "GOC:dsd") Annotation( "GOC:msz") Annotation( "GOC:tfm") Annotation( "GO_REF:0000031") Annotation( "PMID:17992590") Annotation( "PMID:18432934") Annotation( "PMID:8006591") "A germinal center B cell that founds a germinal center, and has the phenotype IgD-positive, CD38-positive, and CD23-negative.") +AnnotationAssertion( "Bm2' B lymphocyte") +AnnotationAssertion( "Bm2' B-cell") +AnnotationAssertion( "Bm2-prime B cell") +AnnotationAssertion( "Bm2-prime B-lymphocyte") +AnnotationAssertion( "germinal center founder cell") +AnnotationAssertion(rdfs:comment "Bm2' B cells are also reportedly CD10-positive, CD39-negative, CD44-negative, CD71-positive, CD77-negative, IgM-positive, IgG-negative, IgA-negative, and IgE-negative.") +AnnotationAssertion(rdfs:label "Bm2' B cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (Bm3 B cell) + +AnnotationAssertion(Annotation( "GOC:dsd") Annotation( "GOC:msz") Annotation( "GO_REF:0000031") Annotation( "PMID:18432934") Annotation( "PMID:8006591") "A germinal center B cell that is rapidly dividing and has the phenotype IgD-negative, CD38-positive, and CD77-positive. Somatic hypermutation of the immunoglobulin V gene region can occur during proliferation of this cell type.") +AnnotationAssertion( "Bm3 B lymphocyte") +AnnotationAssertion( "Bm3 B-cell") +AnnotationAssertion( "Bm3 B-lymphocyte") +AnnotationAssertion(Annotation( "PMID:8006591") "centroblast") +AnnotationAssertion(rdfs:comment "Bm3 B cells are also reportedly CD10-positive, CD23-negative, CD39-negative, CD44-negative, CD71-positive, and CD77-positive.") +AnnotationAssertion(rdfs:label "Bm3 B cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (Bm4 B cell) + +AnnotationAssertion(Annotation( "GOC:dsd") Annotation( "GOC:msz") Annotation( "GO_REF:0000031") Annotation( "PMID:18432934") Annotation( "PMID:8006591") "A germinal center B cell that has the phenotype CD77-negative, IgD-negative, and CD38-positive. These cells have undergone somatic mutation of the B cell receptor.") +AnnotationAssertion( "Bm4 B lymphocyte") +AnnotationAssertion( "Bm4 B-cell") +AnnotationAssertion( "Bm4 B-lymphocyte") +AnnotationAssertion(Annotation( "PMID:17992590") "centrocyte") +AnnotationAssertion(rdfs:comment "Bm4 B cells are also reportedly CD10-positive, CD23-negative, CD39-negative, CD44-positive, and CD71-positive.") +AnnotationAssertion(rdfs:label "Bm4 B cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (Bm5 B cell) + +AnnotationAssertion(Annotation( "GOC:dsd") Annotation( "GOC:msz") Annotation( "GOC:tfm") Annotation( "GO_REF:0000031") Annotation( "PMID:18432934") Annotation( "PMID:8006591") "A memory B cell arising in the germinal center that is IgD-negative and has undergone somatic mutation of the variable region of the immunoglobulin heavy and light chain genes.") +AnnotationAssertion( "Bm5 B lymphocyte") +AnnotationAssertion( "Bm5 B-cell") +AnnotationAssertion( "Bm5 B-lymphocyte") +AnnotationAssertion(rdfs:comment "Bm5 B cells are also reportedly CD10-positive, CD23-negative, CD38-negative, CD39-positive, CD44-positive, CD71-positive, and CD77-negative.") +AnnotationAssertion(rdfs:label "Bm5 B cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (unswitched memory B cell) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:dsd") Annotation( "GOC:rhs") Annotation( "GO_REF:0000031") Annotation( "ISBN:0781765196") Annotation( "PMID:20933013") Annotation( "PMID:22343568") "An unswitched memory B cell is a memory B cell that has the phenotype IgM-positive, IgD-positive, CD27-positive, CD138-negative, IgG-negative, IgE-negative, and IgA-negative.") +AnnotationAssertion( ) +AnnotationAssertion(Annotation( "PMID:22343568") "IgD+ memory B cell") +AnnotationAssertion(Annotation( "HP:0032126") "non-class-switched memory B cell") +AnnotationAssertion( "unswitched memory B lymphocyte") +AnnotationAssertion( "unswitched memory B-cell") +AnnotationAssertion( "unswitched memory B-lymphocyte") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:comment "This cell type is compatible with the HIPC Lyoplate markers for 'IgD+ memory B cell'. Per DSD: Unswitched memory B cells are also reportedly CD48-positive, CD84-positive, CD229-positive, and CD352-positive.") +AnnotationAssertion(rdfs:label "unswitched memory B cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (IgM memory B cell) + +AnnotationAssertion(Annotation( "GOC:dsd") Annotation( "GOC:rhs") Annotation( "GO_REF:0000031") Annotation( "ISBN:0781765196") Annotation( "PMID:19447676") "An IgM memory B cell is an unswitched memory B cell with the phenotype IgM-positive and IgD-negative.") +AnnotationAssertion( "IgM memory B lymphocyte") +AnnotationAssertion( "IgM memory B-cell") +AnnotationAssertion( "IgM memory B-lymphocyte") +AnnotationAssertion( "memory IgM B cell") +AnnotationAssertion( "memory IgM B lymphocyte") +AnnotationAssertion( "memory IgM B-cell") +AnnotationAssertion( "memory IgM B-lymphocyte") +AnnotationAssertion(rdfs:comment "IgM memory B cells are also reportedly CD1c-positive, CD95-positive, CD80-positive, CD84-positive, CD86-positive, CD150-negative, CD229-positive, CD289-positive, and CD290-positive. Transcription factors: Notch2-positive, PAX5-positive, SpiB-positive, Ets1-positive, and OBF1-positive.") +AnnotationAssertion(rdfs:label "IgM memory B cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (class switched memory B cell) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:dsd") Annotation( "GOC:rhs") Annotation( "GO_REF:0000031") Annotation( "ISBN:0781765196") Annotation( "PMID:20933013") Annotation( "PMID:9295047") "A class switched memory B cell is a memory B cell that has undergone Ig class switching and therefore is IgM-negative on the cell surface. These cells are CD27-positive and have either IgG, IgE, or IgA on the cell surface.") +AnnotationAssertion( ) +AnnotationAssertion( "class switched memory B lymphocyte") +AnnotationAssertion( "class switched memory B-cell") +AnnotationAssertion( "class switched memory B-lymphocyte") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:comment "Per DSD: Class switched memory B cells are also reportedly CD48-positive, CD229-positive, and CD352-positive.") +AnnotationAssertion(rdfs:label "class switched memory B cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (IgA memory B cell) + +AnnotationAssertion(Annotation( "GOC:dsd") Annotation( "GOC:msz") Annotation( "GO_REF:0000031") Annotation( "ISBN:0781765196") "A class switched memory B cell that expresses IgA.") +AnnotationAssertion( "IgA memory B lymphocyte") +AnnotationAssertion( "IgA memory B-cell") +AnnotationAssertion( "IgA memory B-lymphocyte") +AnnotationAssertion( "memory IgA B cell") +AnnotationAssertion( "memory IgA B lymphocyte") +AnnotationAssertion( "memory IgA B-cell") +AnnotationAssertion( "memory IgA B-lymphocyte") +AnnotationAssertion(rdfs:comment "IgA memory B cell are also reportedly RORalpha-positive.") +AnnotationAssertion(rdfs:label "IgA memory B cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) + +# Class: (IgG memory B cell) + +AnnotationAssertion(Annotation( "GOC:rhs") Annotation( "GO_REF:0000031") Annotation( "ISBN:0781765196") "An IgG memory B cell is a class switched memory B cell that is class switched and expresses IgG on the cell surface.") +AnnotationAssertion( "IgG memory B lymphocyte") +AnnotationAssertion( "IgG memory B-cell") +AnnotationAssertion( "IgG memory B-lymphocyte") +AnnotationAssertion( "memory IgG B cell") +AnnotationAssertion( "memory IgG B lymphocyte") +AnnotationAssertion( "memory IgG B-cell") +AnnotationAssertion( "memory IgG B-lymphocyte") +AnnotationAssertion(rdfs:label "IgG memory B cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) + +# Class: (plasmablast) + +AnnotationAssertion(Annotation( "GOC:dsd") Annotation( "GOC:msz") Annotation( "GOC:tfm") Annotation( "GO_REF:0000031") Annotation( "PMCID:PMC2673126") "An activated mature (naive or memory) B cell that is secreting immunoglobulin, typified by being CD27-positive, CD38-positive, CD138-negative.") +AnnotationAssertion( ) +AnnotationAssertion( "CD20-negative B cell") +AnnotationAssertion( "FMA:84371") +AnnotationAssertion( "CD27-positive, CD38-positive, CD20-negative B cell") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:comment "This cell type is compatible with the HIPC Lyoplate markers for 'plasmablast'. Plasmablasts are also reportedly CD48-positive, CD63-positive, CD229-positive, CD270-positive, CD319-positive, CD352-positive, CD361-positive, and IgD-negative.") +AnnotationAssertion(rdfs:label "plasmablast") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (double negative memory B cell) + +AnnotationAssertion(Annotation( "GOC:msz") Annotation( "GOC:tfm") Annotation( "GO_REF:0000031") "A memory B cell with the phenotype IgD-negative and CD27-negative.") +AnnotationAssertion( "dn memory B cell") +AnnotationAssertion( "dn memory B lymphocyte") +AnnotationAssertion( "dn memory B-cell") +AnnotationAssertion( "dn memory B-lymphocyte") +AnnotationAssertion( "double negative memory B lymphocyte") +AnnotationAssertion( "double negative memory B-cell") +AnnotationAssertion( "double negative memory B-lymphocyte") +AnnotationAssertion(rdfs:label "double negative memory B cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) # Class: (hematopoietic cell) @@ -19625,8 +35011,147 @@ AnnotationAssertion( ) AnnotationAssertion(rdfs:comment "Originally described in the dendritic cell ontology (DC_CL:0000003)(PMID:19243617) These cells are also CD20-negative, MHCII-positive.") AnnotationAssertion(rdfs:label "conventional dendritic cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) +# Class: (CD34-positive, CD38-positive common myeloid progenitor OR CD34-positive, CD38-positive common lymphoid progenitor) + +AnnotationAssertion( "CD71-positive common myeloid precursor OR CD7-negative lymphoid precursor OR CD7-positive lymphoid") +AnnotationAssertion(rdfs:comment "Originally described in the dendritic cell ontology (DC_CL:1100000)(PMID:19243617).") +AnnotationAssertion(rdfs:label "CD34-positive, CD38-positive common myeloid progenitor OR CD34-positive, CD38-positive common lymphoid progenitor") +EquivalentClasses( ObjectUnionOf( )) +SubClassOf( ) + +# Class: (Kit and Sca1-positive hematopoietic stem cell) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:amm") Annotation( "GOC:tfm") Annotation( "GO_REF:0000031") Annotation( "PMID:17952047") Annotation( "PMID:19022770") "A hematopoietic stem cell that has plasma membrane part Kit-positive, SCA-1-positive, CD150-positive and CD34-negative.") +AnnotationAssertion( "LSK stem cell") +AnnotationAssertion( "Sca1-positive hematopoietic stem cell") +AnnotationAssertion(rdfs:comment "Cell markers are associated with mouse hematopoietic stem cell. Originally described in the dendritic cell ontology (DC_CL:0000043)(PMID:19243617).") +AnnotationAssertion(rdfs:label "Kit and Sca1-positive hematopoietic stem cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) +DisjointClasses( ) + +# Class: (CD7-negative lymphoid progenitor OR granulocyte monocyte progenitor) + +AnnotationAssertion(rdfs:comment "Originally described in the dendritic cell ontology (DC_CL:1110000)(PMID:19243617).") +AnnotationAssertion(rdfs:label "CD7-negative lymphoid progenitor OR granulocyte monocyte progenitor") +EquivalentClasses( ObjectUnionOf( )) +SubClassOf( ) + +# Class: (CD115-positive monocyte OR common dendritic progenitor) + +AnnotationAssertion(rdfs:comment "Originally described in the dendritic cell ontology (DC_CL:1111000)(PMID:19243617).") +AnnotationAssertion(rdfs:label "CD115-positive monocyte OR common dendritic progenitor") +EquivalentClasses( ObjectUnionOf( )) +SubClassOf( ) + +# Class: (CD34-positive, CD38-positive common lymphoid progenitor) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:amm") Annotation( "GOC:tfm") Annotation( "GO_REF:0000031") Annotation( "PMCID:PMC2346585") Annotation( "PMID:19022770") "A common lymphoid progenitor that is CD10-positive, CD45RA-positive, CD34-positive and CD38-positive.") +AnnotationAssertion( "CD10-positive common lymphocyte precursor") +AnnotationAssertion( "CD10-positive common lymphocyte progenitor") +AnnotationAssertion( "CD10-positive common lymphoid precursor") +AnnotationAssertion(rdfs:comment "These markers are associated with human common lymphoid progenitors. Originally described in the dendritic cell ontology (DC_CL:0000032)(PMID:19243617).") +AnnotationAssertion(rdfs:label "CD34-positive, CD38-positive common lymphoid progenitor") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) +SubClassOf( ObjectSomeValuesFrom( )) +DisjointClasses( ) + +# Class: (CD115-positive monocyte) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:amm") Annotation( "GO_REF:0000031") Annotation( "PMID:17952047") "CD115-positive monocyte is a monocyte that is CD115-positive and CD11b-positive.") +AnnotationAssertion(rdfs:comment "These markers are associated with human cells. Originally described in the dendritic cell ontology (DC_CL:0000033)(PMID:19243617).") +AnnotationAssertion(rdfs:label "CD115-positive monocyte") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (Kit-positive, CD34-positive common myeloid progenitor) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:amm") Annotation( "GOC:tfm") Annotation( "GO_REF:0000031") Annotation( "PMID:1261582") Annotation( "PMID:17952047") Annotation( "http://www.immgen.org/index_content.html") "A common myeloid progenitor that is Kit-positive and CD34-positive, Il7ra-negative, and is SCA1-low and Fcgr2-low and Fcgr3-low.") +AnnotationAssertion( "CD117-positive common myeloid precursor") +AnnotationAssertion(rdfs:comment "Markers are associated with mouse cells. Originally described in the dendritic cell ontology (DC_CL:0000034)(PMID:19243617).") +AnnotationAssertion(rdfs:label "Kit-positive, CD34-positive common myeloid progenitor") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) +SubClassOf( ObjectSomeValuesFrom( )) +DisjointClasses( ) + +# Class: (CD34-positive, CD38-negative hematopoietic stem cell) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:amm") Annotation( "GOC:tfm") Annotation( "GO_REF:0000031") Annotation( "PMID:10430905") Annotation( "PMID:11750107") Annotation( "PMID:16551251") Annotation( "PMID:20024907") Annotation( "PMID:9389721") "CD133-positive hematopoietic stem cell is a hematopoietic stem cell that is CD34-positive, CD90-positive, and CD133-positive.") +AnnotationAssertion( "CALOHA:TS-0448") +AnnotationAssertion( "FMA:86475") +AnnotationAssertion(Annotation( "PMID:16140871") "CD133-positive hematopoietic stem cell") +AnnotationAssertion(rdfs:comment "Cell markers are associated with human hematopoietic stem cells. Originally described in the dendritic cell ontology (DC_CL:0000035)(PMID:19243617).") +AnnotationAssertion(rdfs:label "CD34-positive, CD38-negative hematopoietic stem cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) + +# Class: (Kit-positive, Sca1-positive common lymphoid progenitor) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:amm") Annotation( "GOC:tfm") Annotation( "GO_REF:0000031") Annotation( "PMID:17952047") Annotation( "http://www.immgen.org/index_content.html") "A common lymphoid progenitor that is Kit-low, FLT3-positive, IL7ralpha-positive, and SCA1-low.") +AnnotationAssertion( "CD217-positive common lymphocyte precursor") +AnnotationAssertion( "CD217-positive common lymphocyte progenitor") +AnnotationAssertion( "CD217-positive common lymphoid precursor") +AnnotationAssertion(rdfs:comment "Markers are associated with mouse cells.") +AnnotationAssertion(rdfs:label "Kit-positive, Sca1-positive common lymphoid progenitor") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (CD34-positive, CD38-positive common myeloid progenitor) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:amm") Annotation( "GO_REF:0000031") Annotation( "PMCID:PMC2626675") Annotation( "PMID:16551251") "A common myeloid progenitor that is CD34-positive, CD38-positive, IL3ra-low, CD10-negative, CD7-negative, CD45RA-negative, and IL-5Ralpha-negative.") +AnnotationAssertion( "CD71-positive common myeloid precursor") +AnnotationAssertion(rdfs:comment "Markers are associated with human cell type. Originally described in the dendritic cell ontology (DC_CL:0000038)(PMID:19243617).") +AnnotationAssertion(rdfs:label "CD34-positive, CD38-positive common myeloid progenitor") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (CD7-negative lymphoid progenitor cell) + +AnnotationAssertion(Annotation( "GOC:amm") Annotation( "GO_REF:0000031") Annotation( "PMID:16551251") "CD7-negative lymphoid progenitor cell is a lymphoid progenitor cell that is CD34-positive, CD7-negative and CD45RA-negative.") +AnnotationAssertion( "CD7-negative lymphoid precursor") +AnnotationAssertion(rdfs:comment "These markers are associated with human cells. Originally described in the dendritic cell ontology (DC_CL:0000039)(PMID:19243617).") +AnnotationAssertion(rdfs:label "CD7-negative lymphoid progenitor cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (CD7-positive lymphoid progenitor cell) + +AnnotationAssertion(Annotation( "GOC:amm") Annotation( "GOC:tfm") Annotation( "GO_REF:0000031") Annotation( "PMID:16551251") Annotation( "PMID:19491395") "CD7-positive lymphoid progenitor cell is a lymphoid progenitor cell that is CD34-positive, CD7-positive and is CD45RA-negative.") +AnnotationAssertion( "CD7-positive lymphoid precursor") +AnnotationAssertion(rdfs:comment "These markers are associated with human cells. Originally described in the dendritic cell ontology (DC_CL:0000040)(PMID:19243617).") +AnnotationAssertion(rdfs:label "CD7-positive lymphoid progenitor cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (common dendritic progenitor) + +AnnotationAssertion(Annotation( "GOC:amm") Annotation( "GOC:tfm") Annotation( "GO_REF:0000031") Annotation( "PMID:16551251") Annotation( "PMID:17922016") Annotation( "PMID:19286519") "Common dendritic precursor is a hematopoietic progenitor cell that is CD117-low, CD135-positive, CD115-positive and lacks plasma membrane parts for hematopoietic lineage markers.") +AnnotationAssertion(Annotation( "PMID:21219184") "CDP") +AnnotationAssertion( "common dendritic precursor") +AnnotationAssertion(Annotation( "PMID:21219184") "pro-DCs") +AnnotationAssertion(rdfs:comment "Surface markers are for mouse cells. Originally described in the dendritic cell ontology (DC_CL:0000041) CDP are reportedly CD2-negative, CD3-negative, CD4-negative, CD5-negative, CD8a-negative, CD11c-positive, CD14-negative, CD19-negative, CD20-negative, CD56-negative, B220-negative, Ly6g-negative, MHCII-positive, and Ter119-negative. (PMID:19243617).") +AnnotationAssertion(rdfs:label "common dendritic progenitor") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (CD117-positive common myeloid progenitor OR CD217-positive common lymphoid progenitor) + +AnnotationAssertion(rdfs:comment "Originally described in the dendritic cell ontology (DC_CL:1111100)(PMID:19243617).") +AnnotationAssertion(rdfs:label "CD117-positive common myeloid progenitor OR CD217-positive common lymphoid progenitor") +EquivalentClasses( ObjectUnionOf( )) +SubClassOf( ) + # Class: (cerebellar granule cell) AnnotationAssertion(Annotation( "GOC:mah") Annotation( "doi:10.12688/f1000research.15021.1") Annotation( "doi:10.3389/fncir.2020.611841") "An excitatory granule cell with a soma located in the granular layer of cerebellar cortex. A mature cerebellar granule cell has short dendrites with a characteristic claw-like appearance and a long axon that ascends to the molecular layer where it bifurcates (except in non-teleost fish, where it does not bifurcate) and extends mediolaterally to form parallel fibers.") @@ -19634,13 +35159,21 @@ AnnotationAssertion( "doi:10.3389/fncir.2020.611841") "granule cell of the cerebellum") AnnotationAssertion(Annotation( "doi:10.3389/fncir.2020.611841") rdfs:comment "It has been noted in at least some mammalian species that granule cells are the most numerous cell type in the cerebellum and in the brain, with at least 99% of all cerebellar neurons being granule cells.") AnnotationAssertion(rdfs:label "cerebellar granule cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (cortical granule cell) + +AnnotationAssertion(Annotation( "GOC:mah") "Granule cell that is part of the cerebral cortex.") +AnnotationAssertion(rdfs:label "cortical granule cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (hippocampal granule cell) AnnotationAssertion(Annotation( "GOC:mah") "Granule cell with a soma found in the hippocampus.") AnnotationAssertion(rdfs:label "hippocampal granule cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (bone cell) @@ -19651,8 +35184,7 @@ AnnotationAssertion( AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "bone cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (terminally differentiated osteoblast) @@ -19705,9 +35237,9 @@ SubClassOf( "GOC:add") Annotation( "GOC:dsd") Annotation( "GOC:tfm") Annotation( "ISBN:0878932437") Annotation( "PMCID:PMC2212039") Annotation( "PMID:10724173") Annotation( "PMID:16551251") Annotation( "PMID:16647566") "A progenitor cell committed to myeloid lineage, including the megakaryocyte and erythroid lineages. These cells are CD34-positive, and express Gata1, Gata2, C/EBPa, and Pu.1.") AnnotationAssertion( "common myeloid precursor, CD34-positive") -AnnotationAssertion(Annotation( "ISBN:0878932437") Annotation( ) "CFU-GEMM") -AnnotationAssertion(Annotation( "ISBN:0878932437") Annotation( ) "CFU-S") -AnnotationAssertion(Annotation( "ISBN:0878932437") Annotation( ) "CMP") +AnnotationAssertion(Annotation( "ISBN:0878932437") Annotation( ) "CFU-GEMM") +AnnotationAssertion(Annotation( "ISBN:0878932437") Annotation( ) "CFU-S") +AnnotationAssertion(Annotation( "ISBN:0878932437") Annotation( ) "CMP") AnnotationAssertion(Annotation( "ISBN:0878932437") "colony forming unit granulocyte, erythrocyte, macrophage, and megakaryocyte") AnnotationAssertion(Annotation( "ISBN:0878932437") "multipotential myeloid stem cell") AnnotationAssertion(Annotation( "ISBN:0878932437") "myeloid stem cell") @@ -19732,8 +35264,8 @@ SubClassOf( ObjectSomeValuesFrom( "GOC:add") Annotation( "ISBN:0721601464") "A progenitor cell committed to the erythroid lineage. This cell is ter119-positive but lacks expression of other hematopoietic lineage markers (lin-negative).") AnnotationAssertion( "BTO:0004911") -AnnotationAssertion(Annotation( ) "BFU-E") -AnnotationAssertion(Annotation( ) "CFU-E") +AnnotationAssertion(Annotation( ) "BFU-E") +AnnotationAssertion(Annotation( ) "CFU-E") AnnotationAssertion( "blast forming unit erythroid") AnnotationAssertion( "burst forming unit erythroid") AnnotationAssertion( "colony forming unit erythroid") @@ -19761,8 +35293,86 @@ AnnotationAssertion( "CD19+ B cell") AnnotationAssertion( "CD19-positive B cell") AnnotationAssertion(rdfs:label "B cell, CD19-positive") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (Kit-positive erythroid progenitor cell) + +AnnotationAssertion(Annotation( "GOC:ak") Annotation( "GOC:tfm") Annotation( "PMID:19805084") Annotation( "http://www.immgen.org/index_content.html") "An erythroid progenitor cell is Kit-positive, Ly6A-negative, CD41-negative, CD127-negative, and CD123-negative. This cell type is also described as being lin-negative, Kit-positive, CD150-negative, CD41-negative, CD105-positive, and FcgR-negative.") +AnnotationAssertion( ) +AnnotationAssertion( "2010-04-26T10:14:16Z") +AnnotationAssertion( "c- Kit-positive erythroid progenitor cell") +AnnotationAssertion(rdfs:comment "Markers found on mouse cells.") +AnnotationAssertion(rdfs:label "Kit-positive erythroid progenitor cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (CD34-positive, CD38-positive granulocyte monocyte progenitor) + +AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:12615892") Annotation( "PMID:19022770") "A granulocyte monocyte progenitor is CD34-positive, CD38-positive, IL-3receptor-alpha-positive and is CD45RA-negative.") +AnnotationAssertion( ) +AnnotationAssertion( "2010-01-13T03:19:22Z") +AnnotationAssertion(rdfs:comment "Markers are for human cells. According to different research groups, CD45RA is present or absent on this cell population.") +AnnotationAssertion(rdfs:label "CD34-positive, CD38-positive granulocyte monocyte progenitor") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (Kit-positive granulocyte monocyte progenitor) + +AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:12615892") Annotation( "PMID:16322423") Annotation( "PMID:19022770") Annotation( "PMID:19273628") Annotation( "http://www.immgen.org/index_content.html") "A granulocyte monocyte progenitor that is Kit-positive, CD34-positive, Fc-gamma receptor II/II-positive, and is Sca-1-negative, Il7ra-negative, Cxc3r1-negative, and CD90-negative.") +AnnotationAssertion( ) +AnnotationAssertion( "2010-01-13T03:19:28Z") +AnnotationAssertion(rdfs:comment "Markers are found on mouse cells.") +AnnotationAssertion(rdfs:label "Kit-positive granulocyte monocyte progenitor") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (CD34-positive, GlyA-negative erythroid progenitor cell) + +AnnotationAssertion(Annotation( "GOC:ak") Annotation( "GOC:tfm") Annotation( "PMID:19621348") "An erythroid progenitor cell that is CD34-positive and is GlyA-negative.") +AnnotationAssertion( ) +AnnotationAssertion( "2010-04-26T10:14:30Z") +AnnotationAssertion( "FMA:83517") +AnnotationAssertion(rdfs:comment "Cell markers associated with human cells.") +AnnotationAssertion(rdfs:label "CD34-positive, GlyA-negative erythroid progenitor cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (CD34-negative, GlyA-negative proerythroblast) + +AnnotationAssertion(Annotation( "GOC:ak") Annotation( "GOC:tfm") Annotation( "PMID:19621348") "A proerythoblast that is CD34-negative and GlyA-negative.") +AnnotationAssertion( ) +AnnotationAssertion( "2010-04-26T10:31:50Z") +AnnotationAssertion(rdfs:comment "Cell surface markers are associated with human cells.") +AnnotationAssertion(rdfs:label "CD34-negative, GlyA-negative proerythroblast") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (CD34-positive, CD38-positive megakaryocyte erythroid progenitor cell) + +AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:12615892") Annotation( "PMID:190227700") "A megakaryocyte erythroid progenitor cell is CD34-positive, CD38-positive and is IL3-receptor alpha-negative and CD45RA-negative.") +AnnotationAssertion( ) +AnnotationAssertion( "2010-01-13T03:43:10Z") +AnnotationAssertion(rdfs:comment "Markers are associated with human cell type.") +AnnotationAssertion(rdfs:label "CD34-positive, CD38-positive megakaryocyte erythroid progenitor cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) + +# Class: (Kit-positive, CD34-negative megakaryocyte erythroid progenitor cell) + +AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:12615892") Annotation( "PMID:19022770") Annotation( "http://www.immgen.org/index_content.html") "A megakaryocyte erythroid progenitor cell that is Kit-positive and is Sca1-negative, CD34-negative, CD90-negative, IL7r-alpha-negative and Fcgr II/III-low.") +AnnotationAssertion( ) +AnnotationAssertion( "2010-01-13T03:43:12Z") +AnnotationAssertion(rdfs:comment "Markers are associated with mouse cells.") +AnnotationAssertion(rdfs:label "Kit-positive, CD34-negative megakaryocyte erythroid progenitor cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) + # Class: (macrophage dendritic cell progenitor) AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:19273628") "A progenitor cell that can give rise to plasmacytoid and myeloid dendritic cells, and to monocytes and macrophages.") @@ -19770,9 +35380,143 @@ AnnotationAssertion( "2010-01-19T02:51:58Z") AnnotationAssertion( "MDP") AnnotationAssertion(rdfs:label "macrophage dendritic cell progenitor") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (Kit-positive macrophage dendritic cell progenitor) + +AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:19273628") "A progenitor cell that can give rise to plasmacytoid and myeloid dendritic cells, and to monocytes and macrophages. Marker for this cell is Kit-high, CD115-positive, CD135-positive, Cx3cr1-positive, and is Il7ra-negative.") +AnnotationAssertion( ) +AnnotationAssertion( "2010-01-26T02:43:40Z") +AnnotationAssertion( "murine MDP") +AnnotationAssertion(rdfs:comment "Markers are associated with mouse cells.") +AnnotationAssertion(rdfs:label "Kit-positive macrophage dendritic cell progenitor") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (Kit-low proerythroblast) + +AnnotationAssertion(Annotation( "GOC:ak") Annotation( "GOC:tfm") Annotation( "PMID:19805084") "A proerythoblast that is Kit-low, Lyg76-positive, and CD71-positive.") +AnnotationAssertion( ) +AnnotationAssertion( "2010-04-26T10:31:56Z") +AnnotationAssertion(rdfs:comment "Markers are associated with mouse cells.") +AnnotationAssertion(rdfs:label "Kit-low proerythroblast") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (GlyA-positive basophilic erythroblast) + +AnnotationAssertion(Annotation( "GOC:ak") Annotation( "GOC:tfm") Annotation( "PMID:1638021") "A basophilic erythroblast that is GlyA-positive.") +AnnotationAssertion( ) +AnnotationAssertion( "2010-04-26T10:41:15Z") +AnnotationAssertion(rdfs:comment "Markers are associated with human cells.") +AnnotationAssertion(rdfs:label "GlyA-positive basophilic erythroblast") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (Kit-negative, Ly-76 high basophilic erythroblast) + +AnnotationAssertion(Annotation( "GOC:ak") Annotation( "GOC:tfm") Annotation( "PMID:19805084") "A basophilic erythroblast that is Lyg 76-high and is Kit-negative.") +AnnotationAssertion( ) +AnnotationAssertion( "2010-04-26T10:41:22Z") +AnnotationAssertion(rdfs:comment "Cell surface markers are associated with mouse cells.") +AnnotationAssertion(rdfs:label "Kit-negative, Ly-76 high basophilic erythroblast") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (Kit-negative, Ly-76 high polychromatophilic erythroblast) + +AnnotationAssertion(Annotation( "GOC:ak") Annotation( "GOC:tfm") Annotation( "PMID:19805084") "A polychromatophilic erythroblast that is Lyg 76-high and is Kit-negative.") +AnnotationAssertion( ) +AnnotationAssertion( "2010-04-26T10:53:11Z") +AnnotationAssertion( "late basophilic and polychromatophilic erythroblast") +AnnotationAssertion(rdfs:label "Kit-negative, Ly-76 high polychromatophilic erythroblast") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (CD71-low, GlyA-positive polychromatic erythroblast) + +AnnotationAssertion(Annotation( "GOC:ak") Annotation( "GOC:tfm") Annotation( "PMID:1638021") "A polychromatiic erythroblast that is Gly-A-positive and CD71-low.") +AnnotationAssertion( ) +AnnotationAssertion( "2010-04-26T10:53:16Z") +AnnotationAssertion(rdfs:comment "Cell surface markers are associated with human cells.") +AnnotationAssertion(rdfs:label "CD71-low, GlyA-positive polychromatic erythroblast") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (Kit-negative, Ly-76 high orthochromatophilic erythroblasts) + +AnnotationAssertion(Annotation( "GOC:ak") Annotation( "GOC:tfm") Annotation( "PMID:19805084") "An orthochromatophilic erythroblast that is ter119-high, CD71-low, and Kit-negative.") +AnnotationAssertion( ) +AnnotationAssertion( "2010-04-26T11:04:15Z") +AnnotationAssertion(rdfs:comment "Cell surface markers associated with mouse cells.") +AnnotationAssertion(rdfs:label "Kit-negative, Ly-76 high orthochromatophilic erythroblasts") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (CD71-negative, GlyA-positive orthochromatic erythroblast) + +AnnotationAssertion(Annotation( "GOC:ak") Annotation( "GOC:tfm") Annotation( "PMID:1638021") "An erythroblast that is GlyA-positive and CD71-negative.") +AnnotationAssertion( ) +AnnotationAssertion( "2010-04-26T11:04:21Z") +AnnotationAssertion(rdfs:comment "Markers associated with human cells.") +AnnotationAssertion(rdfs:label "CD71-negative, GlyA-positive orthochromatic erythroblast") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (Ly-76 high reticulocyte) + +AnnotationAssertion(Annotation( "GOC:ak") Annotation( "GOC:tfm") Annotation( "PMID:18539294") "A reticulocyte that is Ly76-high and is Kit-negative.") +AnnotationAssertion( ) +AnnotationAssertion( "2010-04-26T11:37:00Z") +AnnotationAssertion(rdfs:comment "Marker associated with mouse cells.") +AnnotationAssertion(rdfs:label "Ly-76 high reticulocyte") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (GlyA-positive reticulocytes) + +AnnotationAssertion(Annotation( "GOC:ak") Annotation( "GOC:tfm") Annotation( "PMID:1638021") "A reticulocyte that is GlyA-positive.") +AnnotationAssertion( ) +AnnotationAssertion( "2010-04-26T11:48:25Z") +AnnotationAssertion(rdfs:comment "Markers is associated with human cells.") +AnnotationAssertion(rdfs:label "GlyA-positive reticulocytes") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (GlyA-positive erythrocyte) + +AnnotationAssertion(Annotation( "GOC:ak") Annotation( "GOC:tfm") Annotation( "PMID:20134094") "An enucleate erythrocyte that is GlyA-positive.") +AnnotationAssertion( ) +AnnotationAssertion( "2010-04-26T11:51:22Z") +AnnotationAssertion(rdfs:comment "Marker is associated with human cell types.") +AnnotationAssertion(rdfs:label "GlyA-positive erythrocyte") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (Ly-76 high positive erythrocyte) + +AnnotationAssertion(Annotation( "GOC:ak") Annotation( "GOC:tfm") Annotation( "PMID:19805084") "An enucleate erythrocyte that is Lyg-76-high.") +AnnotationAssertion( ) +AnnotationAssertion( "2010-04-26T11:51:27Z") +AnnotationAssertion(rdfs:comment "Marker is associated with mouse cell types.") +AnnotationAssertion(rdfs:label "Ly-76 high positive erythrocyte") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (hematopoietic lineage restricted progenitor cell) AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:19022770") "A hematopoietic progenitor cell that is capable of developing into only one lineage of hematopoietic cells.") @@ -19780,6 +35524,7 @@ AnnotationAssertion( "2010-01-06T03:43:20Z") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "hematopoietic lineage restricted progenitor cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) @@ -19793,10 +35538,166 @@ AnnotationAssertion( AnnotationAssertion( ) AnnotationAssertion(rdfs:comment "This cell type is intended to be compatible with any vertebrate hematopoietic oligopotent progenitor cell. For mammalian hematopoietic oligopotent progenitor cells known to be lineage-negative, please use the term 'hematopoietic oligopotent progenitor cell' (CL_0001060).") AnnotationAssertion(rdfs:label "hematopoietic oligopotent progenitor cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (short term hematopoietic stem cell) + +AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:15572596") Annotation( "PMID:19022770") "A hematopoietic stem cell capable of rapid replenishment of myeloerythroid progenitors and limited self renewal capability. This cell is Kit-positive, Sca1-positive, CD34-positive, CD150-positive, and is Flt3-negative.") +AnnotationAssertion( ) +AnnotationAssertion( "2010-01-08T09:19:25Z") +AnnotationAssertion( "ST stem cell") +AnnotationAssertion( "ST-HSC") +AnnotationAssertion(rdfs:comment "Markers are associated with mouse cells. These cells are also reportedly CD11b-low and CD90-low.") +AnnotationAssertion(rdfs:label "short term hematopoietic stem cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (long term hematopoietic stem cell) + +AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:15572596") Annotation( "PMID:17582345") "A hematopoietic stem cell with long term self renewal capability. This cell is Kit-positive, Sca1-positive, CD150-positive, CD90-low, CD34-negative and Flt3-negative.") +AnnotationAssertion( ) +AnnotationAssertion( "2010-01-08T09:19:28Z") +AnnotationAssertion( "LT stem cell") +AnnotationAssertion( "LT-HSC") +AnnotationAssertion(rdfs:comment "Markers are associated with mouse cells.") +AnnotationAssertion(rdfs:label "long term hematopoietic stem cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) + +# Class: (Slamf1-negative multipotent progenitor cell) + +AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:19022770") "A hematopoietic progenitor that has restricted self-renewal capability. Cell is Kit-positive, Ly6-positive, CD150-negative and Flt3-negative.") +AnnotationAssertion( ) +AnnotationAssertion( "2010-01-08T11:16:33Z") +AnnotationAssertion(rdfs:comment "Markers are associated with mouse cells.") +AnnotationAssertion(rdfs:label "Slamf1-negative multipotent progenitor cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (Slamf1-positive multipotent progenitor cell) + +AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:19022770") "A hematopoietic progenitor that has some limited self-renewal capability. Cells are lin-negative, Kit-positive, CD34-positive, and Slamf1-positive.") +AnnotationAssertion( ) +AnnotationAssertion( "2010-01-08T11:16:35Z") +AnnotationAssertion( "KSL cell") +AnnotationAssertion(rdfs:comment "Markers are associated with mouse cells.") +AnnotationAssertion(rdfs:label "Slamf1-positive multipotent progenitor cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) +SubClassOf( ObjectSomeValuesFrom( )) +DisjointClasses( ) + +# Class: (CD34-positive, CD38-negative multipotent progenitor cell) + +AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:18371405") Annotation( "PMID:19022770") "A hematopoietic multipotent progenitor cell that is CD34-positive, CD38-negative, CD45RA-negative, and CD90-negative.") +AnnotationAssertion( ) +AnnotationAssertion( "2010-01-12T11:14:15Z") +AnnotationAssertion(rdfs:comment "Cell markers are associated with human hematopoietic multipotent progenitor cells.") +AnnotationAssertion(rdfs:label "CD34-positive, CD38-negative multipotent progenitor cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (fraction A pre-pro B cell) + +AnnotationAssertion(Annotation( "GOC:ak") Annotation( "GOC:tfm") Annotation( "PMID:12633665") Annotation( "PMID:17582343") Annotation( "http://www.immgen.org/index_content.html") "A pro-B cell that is CD45R/B220-positive, CD43-positive, HSA-low, BP-1-negative and Ly6c-negative. This cell type is also described as being lin-negative, AA4-positive, Kit-positive, IL7Ra-positive and CD45R-positive.") +AnnotationAssertion( ) +AnnotationAssertion( "2010-04-28T10:50:07Z") +AnnotationAssertion( "fraction A") +AnnotationAssertion( "pre pro B cell") +AnnotationAssertion(rdfs:comment "Markers associated with mouse cells.") +AnnotationAssertion(rdfs:label "fraction A pre-pro B cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) + +# Class: (fraction B precursor B cell) + +AnnotationAssertion(Annotation( "GOC:ak") Annotation( "GOC:tfm") Annotation( "PMID:18432934") "A precursor B cell that is CD45RA-positive, CD43-positive, CD24-positive and BP-1-negative.") +AnnotationAssertion( ) +AnnotationAssertion( "2010-04-28T11:56:21Z") +AnnotationAssertion( "Fr. B") +AnnotationAssertion( "Fraction B") +AnnotationAssertion(rdfs:comment "Markers are commonly associated with mouse cells. These cells are also reportedly RAG1-positive and RAG2-positive.") +AnnotationAssertion(rdfs:label "fraction B precursor B cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (fraction C precursor B cell) + +AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:17582343") "A precursor B cell that is CD45R-positive, CD43-positive, CD24-positive, and BP-positive. Intracellularly expression of surrogate light chain, Rag1 and Rag2, TdT, occurs while there is no expression of mu heavy chain.") +AnnotationAssertion( ) +AnnotationAssertion( "2010-04-28T02:04:01Z") +AnnotationAssertion( "Fraction C") +AnnotationAssertion(rdfs:label "fraction C precursor B cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (fraction C' precursor B cell) + +AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:17582343") "A pre-BCR-positive precursor B cell that is CD24-high, CD25-positive, CD43-positive, CD45R-positive and BP-positive.") +AnnotationAssertion( ) +AnnotationAssertion( "2010-04-28T02:13:46Z") +AnnotationAssertion( "Fr. C'") +AnnotationAssertion( "Fraction C-prime") +AnnotationAssertion(rdfs:label "fraction C' precursor B cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (fraction D precursor B cell) + +AnnotationAssertion(Annotation( "GOC:ak") Annotation( "GOC:dsd") Annotation( "GOC:tfm") Annotation( "PMID:17582343") Annotation( "PMID:18432934") Annotation( "http://www.immgen.org/index_content.html") "A pre-B cell that is pre-BCR-negative, and the kappa- and lambda- light immunoglobulin light chain-negative, CD43-low, and is BP-1-positive, CD45R-positive and CD25-positive. This cell type is also described as being AA4-positive, IgM-negative, CD19-positive, CD43-low/negative, and HSA-positive.") +AnnotationAssertion( ) +AnnotationAssertion( "2010-04-28T02:55:16Z") +AnnotationAssertion( "Fr. D") +AnnotationAssertion(Annotation( "GOC:tfm") "fraction D pre-B cell") +AnnotationAssertion(rdfs:comment "Fraction D precursor B cells are also reportedly CD24-positive and sIgD-negative.") +AnnotationAssertion(rdfs:label "fraction D precursor B cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (fraction E immature B cell) + +AnnotationAssertion(Annotation( "GOC:ak") Annotation( "GOC:dsd") Annotation( "GOC:tfm") Annotation( "PMID:17582343") Annotation( "PMID:18432934") "An immature B cell that is IgM-positive, CD45R-positive, CD43-low, CD25-negative, and CD127-negative. This cell type has also been described as being AA4-positive, IgM-positive, CD19-positive, CD43-low/negative, and HSA-positive.") +AnnotationAssertion( ) +AnnotationAssertion( "2010-04-28T03:13:47Z") +AnnotationAssertion(rdfs:comment "Markers associated with mouse cells. These cells are also reportedly sIgD-negative.") +AnnotationAssertion(rdfs:label "fraction E immature B cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (fraction F mature B cell) + +AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:17582343") "A mature B cell subset originally defined as having being CD45R-positive, IgM-positive, IgD-positive and CD43-negative. Subsequent research demonstrated being CD21-positive and CD23-negative and CD93 negative.") +AnnotationAssertion( ) +AnnotationAssertion( "2010-04-30T03:01:48Z") +AnnotationAssertion(rdfs:label "fraction F mature B cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (CD8alpha-positive thymic conventional dendritic cell) + +AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:19273629") Annotation( "http://www.immgen.org/index_content.html") "A conventional thymic dendritic cell that is CD8alpha-positive.") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( "2010-06-07T02:48:36Z") +AnnotationAssertion( "CD8alpha-alpha-positive thymic conventional dendritic cell") +AnnotationAssertion( "DC.8+.Th") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "CD8alpha-positive thymic conventional dendritic cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) + # Class: (type I pneumocyte) AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:20054144") Annotation( "http://www.copewithcytokines.de") "A type I pneumocyte is a flattened, branched pneumocyte that covers more than 98% of the alveolar surface. This large cell has thin (50-100 nm) cytoplasmic extensions to form the air-blood barrier essential for normal gas exchange.") @@ -19819,6 +35720,7 @@ AnnotationAssertion( "type I alveolar epithelial cells") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "type I pneumocyte") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (type II pneumocyte) @@ -19844,6 +35746,7 @@ AnnotationAssertion( "lung type II cell") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "type II pneumocyte") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf( ObjectSomeValuesFrom( )) # Class: (pancreatic acinar cell) @@ -19858,6 +35761,7 @@ AnnotationAssertion( "acinar cell of pancreas") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "pancreatic acinar cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) SubClassOf(Annotation( "true") ) SubClassOf( ObjectSomeValuesFrom( )) @@ -19869,6 +35773,7 @@ AnnotationAssertion( "2010-09-10T10:48:54Z") AnnotationAssertion( "FMA:62939") AnnotationAssertion(rdfs:label "type A enteroendocrine cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (Purkinje myocyte) @@ -19885,6 +35790,30 @@ AnnotationAssertion( "Purkinje myocyte") SubClassOf( ) +# Class: (type II vestibular sensory cell) + +AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "ISBN:0517223651") "Mostly cylindrical, resemble Type 1 in their contents and the presence of a kinocilium and stereocilium apically; much greater variation in size, some almost span the entire thickness of the sensory epithelium, while others are smaller than Type 1; receive multiple efferent nerve boutons around their bases as well as afferent endings, which are small expansions rather than chalices.") +AnnotationAssertion( ) +AnnotationAssertion( "2010-06-29T09:58:13Z") +AnnotationAssertion( "FMA:67909") +AnnotationAssertion( "type 2 vestibular hair cell") +AnnotationAssertion( "type 2 vestibular sensory cell") +AnnotationAssertion( "type II hair cell") +AnnotationAssertion(rdfs:label "type II vestibular sensory cell") +SubClassOf( ) + +# Class: (type I vestibular sensory cell) + +AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "ISBN:0517223651") "Bottle-shaped with narrow neck; broad, rounded basal portion where nucleus is located; stereocilia and a single kinocilium is present apically; receive nerve bouton at their base from an afferent cup-shaped (chalice or calyx) nerve ending.") +AnnotationAssertion( ) +AnnotationAssertion( "2010-06-29T09:58:19Z") +AnnotationAssertion( "FMA:62352") +AnnotationAssertion( "type 1 vestibular hair cell") +AnnotationAssertion( "type 1 vestibular sensory cell") +AnnotationAssertion( "type I hair cell") +AnnotationAssertion(rdfs:label "type I vestibular sensory cell") +SubClassOf( ) + # Class: (nodal myocyte) AnnotationAssertion(Annotation( "FMA:67101") Annotation( "GOC:tfm") "A specialized cardiac myocyte in the sinoatrial and atrioventricular nodes. The cell is slender and fusiform confined to the nodal center, circumferentially arranged around the nodal artery.") @@ -19918,6 +35847,15 @@ AnnotationAssertion(rdfs:label "myoc SubClassOf( ) SubClassOf( ) +# Class: (brush cell of trachebronchial tree) + +AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "ISBN:0517223651") Annotation( "PMID:15817800") "Infrequent type of columnar epithelial cell. This cell is characterized by the presence of a tuft of blunt, squat microvilli (approximately 120-140/cell) on the cell surface. The microvilli contain filaments that stretch into the underlying cytoplasm. They have a distinctive pear shape with a wide base and a narrow microvillous apex. Function not known.") +AnnotationAssertion( ) +AnnotationAssertion( "2010-06-29T03:22:46Z") +AnnotationAssertion( "pulmonary brush cell") +AnnotationAssertion(rdfs:label "brush cell of trachebronchial tree") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (endo-epithelial cell) AnnotationAssertion(Annotation( "FMA:69075") Annotation( "GOC:tfm") "An epithelial cell derived from endoderm.") @@ -19936,7 +35874,6 @@ AnnotationAssertion( AnnotationAssertion( "FMA:69074") AnnotationAssertion(rdfs:label "ecto-epithelial cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) # Class: (meso-epithelial cell) @@ -19947,7 +35884,6 @@ AnnotationAssertion( "epithelial mesenchymal cell") AnnotationAssertion(rdfs:label "meso-epithelial cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) # Class: (pancreatic ductal cell) @@ -19997,6 +35933,7 @@ AnnotationAssertion( "adrenal secreting cell of the adrenal medulla") AnnotationAssertion( "epiniphrine secreting cell of the adrenal medulla") AnnotationAssertion(rdfs:label "type II cell of adrenal medulla") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) # Class: (type I cell of adrenal medulla) @@ -20007,6 +35944,7 @@ AnnotationAssertion( AnnotationAssertion( "FMA:69321") AnnotationAssertion( "noradrenergic chromaffin cell") AnnotationAssertion(rdfs:label "type I cell of adrenal medulla") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) # Class: (specialized cardiac myocyte) @@ -20018,6 +35956,34 @@ AnnotationAssertion( "specialized cardiac myocyte") SubClassOf( ) +# Class: (nongranular leukocyte) + +AnnotationAssertion(Annotation( "GOC:tfm") "A leukocyte that lacks granules.") +AnnotationAssertion( ) +AnnotationAssertion( "2010-07-22T11:30:33Z") +AnnotationAssertion( "FMA:62855") +AnnotationAssertion( "agranular leukocyte") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "nongranular leukocyte") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) + +# Class: (interstitial cell of Cajal) + +AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:16460275") Annotation( "PMID:19520112") "This is a cell found in the gastrointestinal tract of mammals and serves as a pacemaker that triggers gut contraction. ICCs mediate inputs from the enteric nervous system to smooth muscle cells and are thought to be the cells from which gastrointestinal stromal tumors (GISTs) arise.") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( "2010-07-22T03:26:00Z") +AnnotationAssertion( "BTO:0003914") +AnnotationAssertion( "FMA:86573") +AnnotationAssertion( "ICC") +AnnotationAssertion(Annotation( "GOC:pr") "intestinal pacemaker cell") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:comment "Some argue this cell type is of mesenchymal origin.") +AnnotationAssertion(rdfs:label "interstitial cell of Cajal") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) + # Class: (bone marrow cell) AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "ISBN:0618947256") "A cell found in the bone marrow. This can include fibroblasts, macrophages, adipocytes, osteoblasts, osteoclasts, endothelial cells and hematopoietic cells.") @@ -20028,6 +35994,7 @@ AnnotationAssertion( "MESH:D001854") AnnotationAssertion(rdfs:comment "MH consider whether bone marrow cells are bone cells in the structural sense vs. being part of bone organ sense.") AnnotationAssertion(rdfs:label "bone marrow cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) # Class: (hilus cell of ovary) @@ -20043,6 +36010,16 @@ AnnotationAssertion(rdfs:label "hilu SubClassOf( ) SubClassOf( ) +# Class: (internodal tract myocyte) + +AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "ISBN:0781729300") "A specialised myocyte that lies between the sinoatrial node and the atrioventricular node and is involved in the conduction of electrical signals.") +AnnotationAssertion( ) +AnnotationAssertion( "2010-08-23T11:24:11Z") +AnnotationAssertion( "FMA:223275") +AnnotationAssertion(rdfs:label "internodal tract myocyte") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + # Class: (cortical cell of adrenal gland) AnnotationAssertion(Annotation( "GOC:tfm") "A cell of the adrenal cortex. Cell types include those that synthesize and secrete chemical derivatives (steroids) of cholesterol.") @@ -20052,10 +36029,267 @@ AnnotationAssertion( "adrenal cortex cell") AnnotationAssertion( "adrenocortical cell") AnnotationAssertion(rdfs:label "cortical cell of adrenal gland") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf(Annotation( "true") ) +# Class: (type I cell of adrenal cortex) + +AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "ISBN:0517223651") "A small, polyhedral, cell found in rounded groups or curved columns with deeply staining nuclei, scanty basophilic cytoplasm and a few lipid droplets. This cell in the zona glomerulosa produces mineralocorticoids.") +AnnotationAssertion( ) +AnnotationAssertion( "2010-08-24T01:42:02Z") +AnnotationAssertion( "FMA:69273") +AnnotationAssertion( "epithelial cell of zona glomerulosa of adrenal gland") +AnnotationAssertion(rdfs:label "type I cell of adrenal cortex") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf(Annotation( "true") ) + +# Class: (CD38-positive naive B cell) + +AnnotationAssertion(Annotation( "GOC:dsd") Annotation( "GOC:rhs") Annotation( "GOC:tfm") Annotation( "PMID:20123131") "A CD38-positive naive B cell is a mature B cell that has the phenotype CD38-positive, surface IgD-positive, surface IgM-positive, and CD27-negative, and that has not yet been activated by antigen in the periphery.") +AnnotationAssertion( "CD38+ naive B cell") +AnnotationAssertion( "CD38+ naive B lymphocyte") +AnnotationAssertion( "CD38+ naive B-cell") +AnnotationAssertion( "CD38+ naive B-lymphocyte") +AnnotationAssertion( "CD38-positive naive B lymphocyte") +AnnotationAssertion( "CD38-positive naive B-cell") +AnnotationAssertion( "CD38-positive naive B-lymphocyte") +AnnotationAssertion(rdfs:label "CD38-positive naive B cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) + +# Class: (CD38-negative naive B cell) + +AnnotationAssertion(Annotation( "GOC:dsd") Annotation( "GOC:rhs") Annotation( "GOC:tfm") Annotation( "PMID:20123131") "A CD38-negative naive B cell is a mature B cell that has the phenotype CD38-negative, surface IgD-positive, surface IgM-positive, and CD27-negative, that has not yet been activated by antigen in the periphery.") +AnnotationAssertion( "CD38- naive B cell") +AnnotationAssertion( "CD38- naive B lymphocyte") +AnnotationAssertion( "CD38- naive B-cell") +AnnotationAssertion( "CD38- naive B-lymphocyte") +AnnotationAssertion( "CD38-negative naive B lymphocyte") +AnnotationAssertion( "CD38-negative naive B-cell") +AnnotationAssertion( "CD38-negative naive B-lymphocyte") +AnnotationAssertion(rdfs:label "CD38-negative naive B cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) + +# Class: (IgG-positive double negative memory B cell) + +AnnotationAssertion(Annotation( "GOC:dsd") Annotation( "GOC:rhs") Annotation( "GOC:tfm") Annotation( "PMID:20123131") "An IgG-positive double negative memory B cell is a double negative memory B cell with the phenotype IgG-positive, IgD-negative, and CD27-negative.") +AnnotationAssertion( "IgG+ dn memory B cell") +AnnotationAssertion( "IgG+ dn memory B lymphocyte") +AnnotationAssertion( "IgG+ dn memory B-cell") +AnnotationAssertion( "IgG+ dn memory B-lymphocyte") +AnnotationAssertion( "IgG+ double negative memory B cell") +AnnotationAssertion( "IgG+ double negative memory B lymphocyte") +AnnotationAssertion( "IgG+ double negative memory B-cell") +AnnotationAssertion( "IgG+ double negative memory B-lymphocyte") +AnnotationAssertion( "IgG-positive dn memory B cell") +AnnotationAssertion( "IgG-positive dn memory B lymphocyte") +AnnotationAssertion( "IgG-positive dn memory B-cell") +AnnotationAssertion( "IgG-positive dn memory B-lymphocyte") +AnnotationAssertion( "IgG-positive double negative memory B lymphocyte") +AnnotationAssertion( "IgG-positive double negative memory B-cell") +AnnotationAssertion( "IgG-positive double negative memory B-lymphocyte") +AnnotationAssertion(rdfs:label "IgG-positive double negative memory B cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) + +# Class: (IgG-negative double negative memory B cell) + +AnnotationAssertion(Annotation( "GOC:dsd") Annotation( "GOC:rhs") Annotation( "GOC:tfm") Annotation( "PMID:20123131") "An IgG-negative double negative memory B cell is a double negative memory B cell with the phenotype IgG-negative, IgD-negative, and CD27-negative.") +AnnotationAssertion( "IgG- dn memory B cell") +AnnotationAssertion( "IgG- dn memory B lymphocyte") +AnnotationAssertion( "IgG- dn memory B-cell") +AnnotationAssertion( "IgG- dn memory B-lymphocyte") +AnnotationAssertion( "IgG- double negative memory B cell") +AnnotationAssertion( "IgG- double negative memory B lymphocyte") +AnnotationAssertion( "IgG- double negative memory B-cell") +AnnotationAssertion( "IgG- double negative memory B-lymphocyte") +AnnotationAssertion( "IgG-negative dn memory B cell") +AnnotationAssertion( "IgG-negative dn memory B lymphocyte") +AnnotationAssertion( "IgG-negative dn memory B-cell") +AnnotationAssertion( "IgG-negative dn memory B-lymphocyte") +AnnotationAssertion( "IgG-negative double negative memory B lymphocyte") +AnnotationAssertion( "IgG-negative double negative memory B-cell") +AnnotationAssertion( "IgG-negative double negative memory B-lymphocyte") +AnnotationAssertion(rdfs:label "IgG-negative double negative memory B cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) + +# Class: (CD38-positive IgG memory B cell) + +AnnotationAssertion(Annotation( "GOC:dsd") Annotation( "GOC:rhs") Annotation( "GOC:tfm") Annotation( "PMID:20123131") "A CD38-positive IgG memory B cell is a class switched memory B cell that expresses IgG on the cell surface with the phenotype CD38-positive and IgG-positive.") +AnnotationAssertion( "CD38+ IgG memory B cell") +AnnotationAssertion( "CD38+ IgG memory B lymphocyte") +AnnotationAssertion( "CD38+ IgG memory B-cell") +AnnotationAssertion( "CD38+ IgG memory B-lymphocyte") +AnnotationAssertion( "CD38-positive IgG memory B lymphocyte") +AnnotationAssertion( "CD38-positive IgG memory B-cell") +AnnotationAssertion( "CD38-positive IgG memory B-lymphocyte") +AnnotationAssertion(rdfs:label "CD38-positive IgG memory B cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) + +# Class: (IgD-positive CD38-positive IgG memory B cell) + +AnnotationAssertion(Annotation( "GOC:dsd") Annotation( "GOC:rhs") Annotation( "GOC:tfm") Annotation( "PMID:20123131") "An IgD-positive CD38-positive IgG memory B cell is a CD38-positive IgG-positive class switched memory B cell that has class switched and expresses IgD on the cell surface with the phenotype IgD-positive, CD38-positive, and IgG-positive.") +AnnotationAssertion(rdfs:label "IgD-positive CD38-positive IgG memory B cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) + +# Class: (IgD-negative CD38-positive IgG memory B cell) + +AnnotationAssertion(Annotation( "GOC:dsd") Annotation( "GOC:rhs") Annotation( "GOC:tfm") Annotation( "PMID:20123131") "An IgD-negative CD38-positive IgG memory B cell is a CD38-positive IgG-positive that has class switched and lacks expression of IgD on the cell surface with the phenotype IgD-negative, CD38-positive, and IgG-positive.") +AnnotationAssertion(rdfs:label "IgD-negative CD38-positive IgG memory B cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) + +# Class: (CD38-negative IgG memory B cell) + +AnnotationAssertion(Annotation( "GOC:dsd") Annotation( "GOC:rhs") Annotation( "GOC:tfm") Annotation( "PMID:20123131") "A CD38-negative IgG memory B cell is a IgG-positive class switched memory B cell that has class switched and expresses IgG on the cell surface with the phenotype CD38-negative, IgD-negative, and IgG-positive.") +AnnotationAssertion(rdfs:label "CD38-negative IgG memory B cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) + +# Class: (B220-positive CD38-positive naive B cell) + +AnnotationAssertion(Annotation( "GOC:dsd") Annotation( "GOC:rhs") Annotation( "GOC:tfm") Annotation( "PMID:20123131") "A B220-positive CD38-positive naive B cell is a CD38-positive naive B cell that has the phenotype B220-positive, CD38-positive, surface IgD-positive, surface IgM-positive, and CD27-negative, and that has not yet been activated by antigen in the periphery.") +AnnotationAssertion( "B220+CD38+ naive B cell") +AnnotationAssertion( "B220+CD38+ naive B lymphocyte") +AnnotationAssertion( "B220+CD38+ naive B-cell") +AnnotationAssertion( "B220+CD38+ naive B-lymphocyte") +AnnotationAssertion( "B220-positive CD38-positive naive B lymphocyte") +AnnotationAssertion( "B220-positive CD38-positive naive B-cell") +AnnotationAssertion( "B220-positive CD38-positive naive B-lymphocyte") +AnnotationAssertion( "CD38+B220+ naive B cell") +AnnotationAssertion( "CD38+B220+ naive B lymphocyte") +AnnotationAssertion( "CD38+B220+ naive B-cell") +AnnotationAssertion( "CD38+B220+ naive B-lymphocyte") +AnnotationAssertion(rdfs:label "B220-positive CD38-positive naive B cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) + +# Class: (B220-low CD38-positive naive B cell) + +AnnotationAssertion(Annotation( "GOC:dsd") Annotation( "GOC:rhs") Annotation( "GOC:tfm") Annotation( "PMID:20123131") "A B220-low CD38-positive naive B cell is a CD38-positive naive B cell that has the phenotype B220-low, CD38-positive, surface IgD-positive, surface IgM-positive, and CD27-negative, that has not yet been activated by antigen in the periphery.") +AnnotationAssertion(rdfs:label "B220-low CD38-positive naive B cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) + +# Class: (CD38-negative unswitched memory B cell) + +AnnotationAssertion(Annotation( "GOC:dsd") Annotation( "GOC:rhs") Annotation( "GOC:tfm") Annotation( "PMID:20123131") "An CD38-negative unswitched memory B cell is an unswitched memory B cell that has the phenotype CD38-negative, IgD-positive, CD138-negative, and IgG-negative.") +AnnotationAssertion( "CD38- unswitched memory B cell") +AnnotationAssertion( "CD38- unswitched memory B lymphocyte") +AnnotationAssertion( "CD38- unswitched memory B-cell") +AnnotationAssertion( "CD38- unswitched memory B-lymphocyte") +AnnotationAssertion( "CD38-negative unswitched memory B lymphocyte") +AnnotationAssertion( "CD38-negative unswitched memory B-cell") +AnnotationAssertion( "CD38-negative unswitched memory B-lymphocyte") +AnnotationAssertion(rdfs:label "CD38-negative unswitched memory B cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) + +# Class: (B220-positive CD38-negative unswitched memory B cell) + +AnnotationAssertion(Annotation( "GOC:dsd") Annotation( "GOC:rhs") Annotation( "GOC:tfm") Annotation( "PMID:20123131") "A B220-positive CD38-negative unswitched memory B cell is a CD38-negative unswitched memory B cell that has the phenotype B220-positive, CD38-negative, IgD-positive, CD138-negative, and IgG-negative.") +AnnotationAssertion(rdfs:label "B220-positive CD38-negative unswitched memory B cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) + +# Class: (B220-low CD38-negative unswitched memory B cell) + +AnnotationAssertion(Annotation( "GOC:dsd") Annotation( "GOC:rhs") Annotation( "GOC:tfm") Annotation( "PMID:20123131") "A B220-low CD38-negative unswitched memory B cell is a CD38-negative unswitched memory B cell that has the phenotype B220-low, CD38-negative, IgD-positive, CD138-negative, and IgG-negative.") +AnnotationAssertion(rdfs:label "B220-low CD38-negative unswitched memory B cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) + +# Class: (CD38-positive unswitched memory B cell) + +AnnotationAssertion(Annotation( "GOC:dsd") Annotation( "GOC:rhs") Annotation( "GOC:tfm") Annotation( "PMID:20123131") "A CD38-positive unswitched memory B cell is an unswitched memory B cell that has the phenotype CD38-positive, IgD-positive, CD138-negative, and IgG-negative.") +AnnotationAssertion( "CD38+ unswitched memory B cell") +AnnotationAssertion( "CD38+ unswitched memory B lymphocyte") +AnnotationAssertion( "CD38+ unswitched memory B-cell") +AnnotationAssertion( "CD38+ unswitched memory B-lymphocyte") +AnnotationAssertion( "CD38-positive unswitched memory B lymphocyte") +AnnotationAssertion( "CD38-positive unswitched memory B-cell") +AnnotationAssertion( "CD38-positive unswitched memory B-lymphocyte") +AnnotationAssertion(rdfs:label "CD38-positive unswitched memory B cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) + +# Class: (B220-positive CD38-positive unswitched memory B cell) + +AnnotationAssertion(Annotation( "GOC:dsd") Annotation( "GOC:rhs") Annotation( "GOC:tfm") Annotation( "PMID:20123131") "A B220-positive CD38-positive unswitched memory B cell is a CD38-positive unswitched memory B cell that has the phenotype B220-positive, CD38-positive, IgD-positive, CD138-negative, and IgG-negative.") +AnnotationAssertion(rdfs:label "B220-positive CD38-positive unswitched memory B cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) + +# Class: (B220-low CD38-positive unswitched memory B cell) + +AnnotationAssertion(Annotation( "GOC:dsd") Annotation( "GOC:rhs") Annotation( "GOC:tfm") Annotation( "PMID:20123131") "A B220-low CD38-positive unswitched memory B cell is a CD38-positive unswitched memory B cell that has the phenotype B220-low, CD38-positive, IgD-positive, CD138-negative, and IgG-negative.") +AnnotationAssertion(rdfs:label "B220-low CD38-positive unswitched memory B cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) + +# Class: (IgG-negative class switched memory B cell) + +AnnotationAssertion(Annotation( "GOC:dsd") Annotation( "GOC:rhs") Annotation( "GOC:tfm") Annotation( "PMID:20123131") "A class switched memory B cell that lacks IgG on the cell surface.") +AnnotationAssertion( "IgG- class switched memory B cell") +AnnotationAssertion( "IgG- class switched memory B lymphocyte") +AnnotationAssertion( "IgG- class switched memory B-cell") +AnnotationAssertion( "IgG- class switched memory B-lymphocyte") +AnnotationAssertion( "IgG-negative class switched memory B lymphocyte") +AnnotationAssertion( "IgG-negative class switched memory B-cell") +AnnotationAssertion( "IgG-negative class switched memory B-lymphocyte") +AnnotationAssertion(rdfs:label "IgG-negative class switched memory B cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) + +# Class: (CD38-negative IgG-negative class switched memory B cell) + +AnnotationAssertion(Annotation( "GOC:dsd") Annotation( "GOC:rhs") Annotation( "GOC:tfm") Annotation( "PMID:20123131") "A CD38-negative IgG-negative memory B cell is a IgG-negative class switched memory B cell that lacks IgG on the cell surface with the phenotype CD38-negative and IgG-negative.") +AnnotationAssertion(rdfs:label "CD38-negative IgG-negative class switched memory B cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) + +# Class: (CD38-positive IgG-negative class switched memory B cell) + +AnnotationAssertion(Annotation( "GOC:dsd") Annotation( "GOC:rhs") Annotation( "GOC:tfm") Annotation( "PMID:20123131") "A CD38-positive IgG-negative memory B cell is an IgG-negative class switched memory B cell that lacks IgG on the cell surface with the phenotype CD38-positive and IgG-negative.") +AnnotationAssertion(rdfs:label "CD38-positive IgG-negative class switched memory B cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) + +# Class: (CD24-positive CD38-negative IgG-negative class switched memory B cell) + +AnnotationAssertion(Annotation( "GOC:dsd") Annotation( "GOC:rhs") Annotation( "GOC:tfm") Annotation( "PMID:20123131") "An CD24-positive CD38-negative IgG-negative memory B cell is a CD38-negative IgG-negative class switched memory B cell that lacks IgG on the cell surface with the phenotype CD24-positive, CD38-negative, and IgG-negative.") +AnnotationAssertion(rdfs:label "CD24-positive CD38-negative IgG-negative class switched memory B cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) + +# Class: (CD24-negative CD38-negative IgG-negative class switched memory B cell) + +AnnotationAssertion(Annotation( "GOC:dsd") Annotation( "GOC:rhs") Annotation( "GOC:tfm") Annotation( "PMID:20123131") "A CD24-negative CD38-negative IgG-negative memory B cell is a CD38-negative IgG-negative class switched memory B cell that lacks IgG on the cell surface with the phenotype CD24-negative, CD38-negative, and IgG-negative.") +AnnotationAssertion(rdfs:label "CD24-negative CD38-negative IgG-negative class switched memory B cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) + +# Class: (B220-positive CD38-positive IgG-negative class switched memory B cell) + +AnnotationAssertion(Annotation( "GOC:dsd") Annotation( "GOC:rhs") Annotation( "GOC:tfm") Annotation( "PMID:20123131") "A B220-positive CD38-positive IgG-negative memory B cell is a CD38-positive IgG-negative class switched memory B cell that lacks IgG on the cell surface with the phenotype B220-positive, CD38-positive, and IgG-negative.") +AnnotationAssertion(rdfs:label "B220-positive CD38-positive IgG-negative class switched memory B cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) + +# Class: (B220-low CD38-positive IgG-negative class switched memory B cell) + +AnnotationAssertion(Annotation( "GOC:dsd") Annotation( "GOC:rhs") Annotation( "GOC:tfm") Annotation( "PMID:20123131") "A B220-low CD38-positive IgG-negative memory B cell is a CD38-positive IgG-negative class switched memory B cell that lacks IgG on the cell surface with the phenotype B220-low, CD38-positive, and IgG-positive.") +AnnotationAssertion(rdfs:label "B220-low CD38-positive IgG-negative class switched memory B cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) + # Class: (stromal cell of ovary) AnnotationAssertion(Annotation( "GOC:tfm") "A stomal cell of the ovary") @@ -20064,6 +36298,17 @@ AnnotationAssertion( AnnotationAssertion( "FMA:72299") AnnotationAssertion(Annotation( "GOC:cjm") "ovarian stromal cell") AnnotationAssertion(rdfs:label "stromal cell of ovary") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (stromal cell of ovarian medulla) + +AnnotationAssertion(Annotation( "GOC:tfm") "A stromal cell of the ovarian medulla.") +AnnotationAssertion( ) +AnnotationAssertion( "2010-08-23T12:12:17Z") +AnnotationAssertion( "FMA:256171") +AnnotationAssertion(rdfs:label "stromal cell of ovarian medulla") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) # Class: (type II cell of adrenal cortex) @@ -20098,6 +36343,7 @@ AnnotationAssertion( "lymphatic endothelial cell") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "endothelial cell of lymphatic vessel") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) # Class: (endothelial cell of vascular tree) @@ -20114,6 +36360,34 @@ AnnotationAssertion(rdfs:comment "Th AnnotationAssertion(rdfs:label "endothelial cell of vascular tree") SubClassOf( ) +# Class: (acinar cell of sebaceous gland) + +AnnotationAssertion(Annotation( "GOC:tfm") "A sebum secreting cell of the skin that secretes sebum into the hair follicles.") +AnnotationAssertion( ) +AnnotationAssertion( "2010-08-24T09:27:52Z") +AnnotationAssertion( "sebocyte") +AnnotationAssertion( "BTO:0004613") +AnnotationAssertion( "FMA:70953") +AnnotationAssertion(rdfs:label "acinar cell of sebaceous gland") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) +SubClassOf( ) +SubClassOf( ) + +# Class: (capillary endothelial cell) + +AnnotationAssertion(Annotation( "GOC:tfm") "An endothelial cell found in capillaries.") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( "2010-08-24T10:15:00Z") +AnnotationAssertion( "BTO:0004956") +AnnotationAssertion( "CALOHA:TS-0112") +AnnotationAssertion( "FMA:67756") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "capillary endothelial cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) + # Class: (ciliated columnar cell of tracheobronchial tree) AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "ISBN:0517223651") "A ciliated columnar cell found in the trachea and bronchus. Vary from low to tall columnar; possesses up to 300 cilia at its surface, interspersed with long irregular microvilli with the cilia varying in length from about 6um in the trachea to about 4um in the terminal bronchioles; driving force of the ciliary current in the bronchial tree.") @@ -20136,6 +36410,17 @@ AnnotationAssertion( AnnotationAssertion( "CALOHA:TS-0195") AnnotationAssertion( "FMA:87170") AnnotationAssertion(rdfs:label "dental pulp cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (epithelial cell of uterus) + +AnnotationAssertion(Annotation( "GOC:tfm") "An epithelial cell of the uterus.") +AnnotationAssertion( ) +AnnotationAssertion( "2010-08-24T10:45:54Z") +AnnotationAssertion( "FMA:256161") +AnnotationAssertion(rdfs:label "epithelial cell of uterus") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) # Class: (corneocyte) @@ -20180,6 +36465,7 @@ AnnotationAssertion( "2010-08-26T01:47:13Z") AnnotationAssertion( "FMA:67870") AnnotationAssertion(rdfs:label "olfactory epithelial cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) @@ -20191,8 +36477,20 @@ AnnotationAssertion( AnnotationAssertion( "horizontal basal cell") AnnotationAssertion( "FMA:62303") AnnotationAssertion(rdfs:label "basal cell of olfactory epithelium") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) +# Class: (keratinized cell of the oral mucosa) + +AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:12014572") "A keratinized cell located in the hard palate or gingiva.") +AnnotationAssertion( ) +AnnotationAssertion( "2010-08-26T02:51:30Z") +AnnotationAssertion(rdfs:label "keratinized cell of the oral mucosa") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (extraglomerular mesangial cell) AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "ISBN:0412046911") Annotation( "http:/www.copewithcytokines.de/cope.cgi?key=Lacis%20cells") "A cell that is a specialized type of pericyte providing structural support for the capillary loops of kidney. A flat, elongated cell with extensive fine cytoplasmic processes found outside the kidney glomerulus near the macula densa and bound laterally by afferent and efferent arterioles. Being phagocytic, this cell participates in the continuous turnover of the basal lamina by removing its outer portion containing residues of filtration, while the lamina is renewed on its inner surface by the endothelial cells.") @@ -20204,6 +36502,7 @@ AnnotationAssertion( "polar cushion cells") AnnotationAssertion( "lacis cell") AnnotationAssertion(rdfs:label "extraglomerular mesangial cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf(Annotation( "true") ) SubClassOf(Annotation( "true") ) @@ -20220,6 +36519,18 @@ AnnotationAssertion(rdfs:label "foll SubClassOf( ) SubClassOf( ) +# Class: (folliculostellate cell of pars distalis of adenohypophysis) + +AnnotationAssertion(Annotation( "GOC:tfm") "A supporting cell of the anterior pituitary gland involved in trophic and catabolic processes; expresses a broad spectrum of cytokeratins indicative of their epithelial nature.") +AnnotationAssertion( ) +AnnotationAssertion( "2010-08-25T03:10:10Z") +AnnotationAssertion( "FMA:83102") +AnnotationAssertion( "folliculostellate cell of pars anterior of adenohypophysis") +AnnotationAssertion(rdfs:label "folliculostellate cell of pars distalis of adenohypophysis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) +SubClassOf( ) + # Class: (epithelial cell of stomach) AnnotationAssertion(Annotation( "GOC:tfm") "An epithelial cell found in the lining of the stomach.") @@ -20227,8 +36538,31 @@ AnnotationAssertion( "2010-08-25T03:22:08Z") AnnotationAssertion( "FMA:62948") AnnotationAssertion(rdfs:label "epithelial cell of stomach") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) +# Class: (mucous cell of stomach) + +AnnotationAssertion(Annotation( "GOC:tfm") "A mucous cell in the epithelium of the stomach.") +AnnotationAssertion( ) +AnnotationAssertion( "2010-08-25T03:38:51Z") +AnnotationAssertion( "FMA:63464") +AnnotationAssertion(rdfs:label "mucous cell of stomach") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) +SubClassOf( ) + +# Class: (stem cell of gastric gland) + +AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "ISBN:0517223651") "A stomach epithelial cell that is olumnar in form with a few short apical microvilli; relatively undifferentiated mitotic cell from which other types of gland are derived; few in number, situated in the isthmus region of the gland and base of the gastric pit.") +AnnotationAssertion( ) +AnnotationAssertion( "2010-08-25T03:57:08Z") +AnnotationAssertion( "FMA:62953") +AnnotationAssertion(rdfs:label "stem cell of gastric gland") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) +SubClassOf( ) + # Class: (basal cell of epidermis) AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "ISBN:0517223651") "A basally situated, mitotically active, columnar-shaped keratinocyte attached to the basement membrane.") @@ -20236,9 +36570,32 @@ AnnotationAssertion( "2010-08-26T03:12:49Z") AnnotationAssertion( "FMA:70571") AnnotationAssertion(rdfs:label "basal cell of epidermis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf(Annotation( "true") ) +# Class: (glomerular endothelial cell) + +AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:15840009") "An endothelial cell found in the glomerulus of the kidney. This cell is flattened, highly fenestrated, and plays a vital role in the formation of glomerular ultrafiltrate.") +AnnotationAssertion( ) +AnnotationAssertion( "2010-08-26T10:59:44Z") +AnnotationAssertion( "BTO:0004632") +AnnotationAssertion( "FMA:70970") +AnnotationAssertion(rdfs:label "glomerular endothelial cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) +SubClassOf( ) + +# Class: (granulocytopoietic cell) + +AnnotationAssertion(Annotation( "GOC:tfm") "A cell involved in the formation of a granulocyte.") +AnnotationAssertion( ) +AnnotationAssertion( "2010-08-30T12:54:27Z") +AnnotationAssertion( "FMA:83519") +AnnotationAssertion(rdfs:label "granulocytopoietic cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) + # Class: (monopoietic cell) AnnotationAssertion(Annotation( "GOC:tfm") "A cell involved in the formation of a monocyte (monopoiesis).") @@ -20246,6 +36603,7 @@ AnnotationAssertion( "2010-08-30T01:27:48Z") AnnotationAssertion( "FMA:83552") AnnotationAssertion(rdfs:label "monopoietic cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) # Class: (hepatic stem cell) @@ -20254,7 +36612,7 @@ AnnotationAssertion(Annotation( ) AnnotationAssertion( "2010-08-30T02:00:42Z") AnnotationAssertion( "FMA:86577") -AnnotationAssertion(Annotation( "PMID:18442648") Annotation( ) "HpSC") +AnnotationAssertion(Annotation( "PMID:18442648") Annotation( ) "HpSC") AnnotationAssertion(rdfs:label "hepatic stem cell") AnnotationAssertion(rdfs:seeAlso "https://github.com/obophenotype/cell-ontology/issues/800") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) @@ -20281,6 +36639,17 @@ AnnotationAssertion(rdfs:label "oxyp SubClassOf( ) SubClassOf( ) +# Class: (oxyphil cell of thyroid) + +AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:20013317") "An oncocyte located in the thyroid.") +AnnotationAssertion( ) +AnnotationAssertion( "2010-09-02T11:33:26Z") +AnnotationAssertion( "FMA:87169") +AnnotationAssertion( "Askanazy cells") +AnnotationAssertion( "Hurthle cells") +AnnotationAssertion(rdfs:label "oxyphil cell of thyroid") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (epithelial cell of tracheobronchial tree) AnnotationAssertion(Annotation( "GOC:tfm") "An epithelial cell of the tracheobronchial tree.") @@ -20288,8 +36657,68 @@ AnnotationAssertion( "2010-09-02T02:09:14Z") AnnotationAssertion( "FMA:66816") AnnotationAssertion(rdfs:label "epithelial cell of tracheobronchial tree") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (brush cell of epithelium proper of large intestine) + +AnnotationAssertion(Annotation( "GOC:tfm") "Brush cell found in the epithelial layer of the colon.") +AnnotationAssertion( ) +AnnotationAssertion( "2010-09-02T02:20:50Z") +AnnotationAssertion( "FMA:263222") +AnnotationAssertion(Annotation( "http://orcid.org/0000-0003-4183-8865") "brush cell of large intestine") +AnnotationAssertion(Annotation( "http://orcid.org/0000-0003-4183-8865") "tuft cell of epithelium of large intestine") +AnnotationAssertion(Annotation( "http://orcid.org/0000-0003-4183-8865") "tuft cell of large intestine") +AnnotationAssertion(rdfs:comment "Brush cells are a distinct cell type from brush border cell-types.") +AnnotationAssertion(rdfs:label "brush cell of epithelium proper of large intestine") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (brush cell) + +AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "ISBN:0517223651") Annotation( "PMID:15817800") "A cell type found in the gastrointestinal and respiratory tracts that is characterized by the presence of a tuft of blunt, squat microvilli (120-140 per cell). Function of this cell type is not known.") +AnnotationAssertion( ) +AnnotationAssertion( "2010-09-02T02:28:53Z") +AnnotationAssertion( "FMA:67978") +AnnotationAssertion( "caveolated cell") +AnnotationAssertion( "fibrillovesicular cell") +AnnotationAssertion( "multivesicular cell") +AnnotationAssertion( "tuft cell") +AnnotationAssertion(rdfs:label "brush cell") +SubClassOf( ) + +# Class: (brush cell of lobular bronchiole) + +AnnotationAssertion(Annotation( "GOC:tfm") "A brush cell found in the epithelium of lobular bronchiole.") +AnnotationAssertion( ) +AnnotationAssertion( "2010-09-02T02:38:34Z") +AnnotationAssertion( "FMA:263220") +AnnotationAssertion(rdfs:label "brush cell of lobular bronchiole") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (brush cell of terminal bronchiole) + +AnnotationAssertion(Annotation( "GOC:tfm") "A brush cell of the epithelium in the terminal bronchiole.") +AnnotationAssertion( ) +AnnotationAssertion( "2010-09-02T02:38:36Z") +AnnotationAssertion( "FMA:263228") +AnnotationAssertion(rdfs:label "brush cell of terminal bronchiole") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (brush cell of trachea) + +AnnotationAssertion(Annotation( "GOC:tfm") "Brush cell of the epithelium in the trachea.") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( "2010-09-02T02:38:37Z") +AnnotationAssertion( "FMA:263224") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "brush cell of trachea") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) +SubClassOf(Annotation( "true") ) + # Class: (brush cell of bronchus) AnnotationAssertion(Annotation( "GOC:tfm") "A brush cell found in the epithelium of bronchus.") @@ -20299,6 +36728,7 @@ AnnotationAssertion( AnnotationAssertion( "FMA:263226") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "brush cell of bronchus") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (intermediate epitheliocyte) @@ -20331,6 +36761,73 @@ SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (lens epithelial cell) + +AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "ISBN:0721662544") Annotation( "http://en.wikipedia.org/wiki/Lens_%28anatomy%29#Lens_epithelium") "A cell of the cuboidal epithelium that covers the lens. The cells of the lens epithelium regulate most of the homeostatic functions of the lens. As ions, nutrients, and liquid enter the lens from the aqueous humor, Na+/K+ ATPase pumps in the lens epithelial cells pump ions out of the lens to maintain appropriate lens osmolarity and volume, with equatorially positioned lens epithelium cells contributing most to this current. The activity of the Na+/K+ ATPases keeps water and current flowing through the lens from the poles and exiting through the equatorial regions. The cells of the lens epithelium also serve as the progenitors for new lens fibers. It constantly lays down fibers in the embryo, fetus, infant, and adult, and continues to lay down fibers for lifelong growth.") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( "2010-09-07T10:45:47Z") +AnnotationAssertion( "FMA:67559") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "lens epithelial cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) +SubClassOf( ) + +# Class: (epithelial cell of prostate) + +AnnotationAssertion(Annotation( "GOC:tfm") "An epithelial cell of the prostate.") +AnnotationAssertion( ) +AnnotationAssertion( "2010-09-07T01:49:29Z") +AnnotationAssertion( "FMA:256163") +AnnotationAssertion( "FMA:66817") +AnnotationAssertion( "prostate epithelial cell") +AnnotationAssertion(rdfs:label "epithelial cell of prostate") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) + +# Class: (epithelial cell of prostatic duct) + +AnnotationAssertion(Annotation( "GOC:tfm") "An epithelial cell of prostatic duct.") +AnnotationAssertion( ) +AnnotationAssertion( "2010-09-07T01:55:51Z") +AnnotationAssertion( "FMA:74224") +AnnotationAssertion(Annotation( "FMA:74224") "ductal epithelial cell of prostate") +AnnotationAssertion(rdfs:label "epithelial cell of prostatic duct") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) +SubClassOf( ) + +# Class: (epithelial cell of prostatic acinus) + +AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMCID:PMC2673349") "An epithelial cell of the prostatic acinus.") +AnnotationAssertion( ) +AnnotationAssertion( "2010-09-07T01:55:53Z") +AnnotationAssertion( "FMA:74223") +AnnotationAssertion(Annotation( "FMA:74223") "acinar epithelial cell of prostate") +AnnotationAssertion(rdfs:label "epithelial cell of prostatic acinus") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) + +# Class: (basal cell of prostatic acinus) + +AnnotationAssertion(Annotation( "GOC:tfm") "A cell of the basal layer of the epithelium in the prostatic acinus.") +AnnotationAssertion( ) +AnnotationAssertion( "2010-09-07T01:59:08Z") +AnnotationAssertion( "FMA:74265") +AnnotationAssertion(Annotation( "FMA:74265") "basal epithelial cell of prostatic acinus") +AnnotationAssertion(rdfs:label "basal cell of prostatic acinus") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (basal epithelial cell of prostatic duct) + +AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:15226377") "A cell that constitutes the basal layer of epithelium in the prostatic duct.") +AnnotationAssertion( ) +AnnotationAssertion( "2010-09-07T01:59:12Z") +AnnotationAssertion( "FMA:74226") +AnnotationAssertion(rdfs:label "basal epithelial cell of prostatic duct") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (marrow fibroblast) AnnotationAssertion(Annotation( "GOC:tfm") "A fibroblast in the bone marrow.") @@ -20338,18 +36835,17 @@ AnnotationAssertion( "2010-09-07T02:25:18Z") AnnotationAssertion( "FMA:84377") AnnotationAssertion(rdfs:label "marrow fibroblast") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) # Class: (pulmonary interstitial fibroblast) AnnotationAssertion(Annotation( "GOC:tfm") "A fibroblasts found in interstitial spaces in the pulmonary tract. Greater numbers of these cells are found in idiopathic pulmonary fibrosis.") -AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( "2010-09-07T02:29:38Z") AnnotationAssertion( "FMA:84467") AnnotationAssertion( "pulmonary myofibroblast") AnnotationAssertion( "pulmonary septal cell") -AnnotationAssertion( ) AnnotationAssertion(rdfs:label "pulmonary interstitial fibroblast") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) @@ -20361,7 +36857,7 @@ AnnotationAssertion( "2010-09-07T03:32:33Z") AnnotationAssertion( "FMA:67513") AnnotationAssertion(rdfs:label "nucleate cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (smooth muscle cell of sphincter of pupil) @@ -20399,14 +36895,76 @@ AnnotationAssertion( "pluripotent stem cell") SubClassOf( ) +# Class: (intestinal crypt stem cell) + +AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "ISBN:0517223651") "A cell that is found in a zone occupying the bottom region of the crypt; provide the source of most of the cell types of the intestinal epithelium; proliferate by mitotic division; differentiates into columnar or goblet cells.") +AnnotationAssertion( ) +AnnotationAssertion( "2010-09-08T09:21:22Z") +AnnotationAssertion( "FMA:63379") +AnnotationAssertion( "stem cell of intestinal crypt of Lieberkuhn") +AnnotationAssertion(rdfs:label "intestinal crypt stem cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + # Class: (epithelial cell of alimentary canal) AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "ISBN:0721662544") "An epithelial cell of the musculomembranous digestive tube extending from the mouth to the anus.") AnnotationAssertion( ) AnnotationAssertion( "2010-09-08T09:26:53Z") AnnotationAssertion(rdfs:label "epithelial cell of alimentary canal") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (epithelial cell of esophagus) + +AnnotationAssertion(Annotation( "GOC:tfm") "An epithelial cell of the esophagus.") +AnnotationAssertion( ) +AnnotationAssertion( "2010-09-08T09:28:20Z") +AnnotationAssertion( "FMA:63071") +AnnotationAssertion(rdfs:label "epithelial cell of esophagus") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) + +# Class: (epithelial cell of large intestine) + +AnnotationAssertion(Annotation( "GOC:tfm") "An epithelial cell of the large intestine.") +AnnotationAssertion( ) +AnnotationAssertion( "2010-09-08T09:28:22Z") +AnnotationAssertion( "BTO:0004297") +AnnotationAssertion( "FMA:256157") +AnnotationAssertion( "epithelial cell of colon") +AnnotationAssertion(rdfs:label "epithelial cell of large intestine") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) + +# Class: (epithelial cell of small intestine) + +AnnotationAssertion(Annotation( "GOC:tfm") "An epithelial cell of the small intestine.") +AnnotationAssertion( ) +AnnotationAssertion( "2010-09-08T09:41:46Z") +AnnotationAssertion( "FMA:256159") +AnnotationAssertion(rdfs:label "epithelial cell of small intestine") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) + +# Class: (stromal cell of endometrium) + +AnnotationAssertion(Annotation( "PMID:11331626") Annotation( "PMID:30013421") Annotation( "PMID:30309298") Annotation( "Wiki:Decidualization&oldid=908981933#Endometrial_stromal_cells_(ESCs)") Annotation( "https://doi.org/10.1038/s41591-020-1040-z") "A stromal cell of the endometrium that is fibroblastic in appearance. During decidualization this cell may differentiate into a decidual stromal cell.") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( "2010-09-08T09:50:04Z") +AnnotationAssertion( "CALOHA:TS-1266") +AnnotationAssertion( "FMA:86490") +AnnotationAssertion( "endometrial stromal cell") +AnnotationAssertion(Annotation( "PMID:30309298") "endometrial stromal fibroblast") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "stromal cell of endometrium") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (supporting cell of carotid body) AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:8985136") Annotation( "http://www.copewithcytokines.de/cope.cgi?key=glomus%20cells") "A supportive cell that has characteristics of glial cell. Processes of this cell envelope the junctions between glomus cells and nerve endings.") @@ -20426,6 +36984,7 @@ AnnotationAssertion( AnnotationAssertion( "FMA:256167") AnnotationAssertion( "MESH:D000072637") AnnotationAssertion(rdfs:label "epithelial cell of thyroid gland") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf(Annotation( "true") ) @@ -20450,9 +37009,108 @@ AnnotationAssertion( "2010-09-08T02:29:38Z") AnnotationAssertion( "FMA:70547") AnnotationAssertion(rdfs:label "epithelial cell of parathyroid gland") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf(Annotation( "true") ) +# Class: (endothelial cell of viscerocranial mucosa) + +AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "ISBN:0618947256") "An endothelial cell found in the mucosa associated with the facial skeleton.") +AnnotationAssertion( ) +AnnotationAssertion( "2010-09-14T10:40:12Z") +AnnotationAssertion( "FMA:70627") +AnnotationAssertion(rdfs:label "endothelial cell of viscerocranial mucosa") +SubClassOf( ) + +# Class: (endothelial cell of sinusoid) + +AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "ISBN:0618947256") "An endothelial cell that lines any of the venous cavities through which blood passes in various glands and organs such as the spleen and liver.") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( "2010-09-14T10:57:26Z") +AnnotationAssertion( "FMA:63134") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "endothelial cell of sinusoid") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (type A cell of stomach) + +AnnotationAssertion(Annotation( "GOC:tfm") "A type of enteroendocrine cell found in the stomach that secretes glucagon.") +AnnotationAssertion( ) +AnnotationAssertion( "2010-09-10T10:54:42Z") +AnnotationAssertion( "FMA:83411") +AnnotationAssertion(rdfs:label "type A cell of stomach") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (type D cell of colon) + +AnnotationAssertion(Annotation( "GOC:tfm") "A D cell located in the colon.") +AnnotationAssertion( ) +AnnotationAssertion( "2010-09-10T11:37:35Z") +AnnotationAssertion( "FMA:268744") +AnnotationAssertion( "colon D-cell") +AnnotationAssertion( "colonic delta cell") +AnnotationAssertion( "delta cell of colon") +AnnotationAssertion(rdfs:label "type D cell of colon") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (type D cell of small intestine) + +AnnotationAssertion(Annotation( "GOC:tfm") "A type D cell of the small intestine.") +AnnotationAssertion( ) +AnnotationAssertion( "2010-09-10T01:34:22Z") +AnnotationAssertion( "FMA:268736") +AnnotationAssertion( "delta cell of small intestine") +AnnotationAssertion( "small intestine D-cell") +AnnotationAssertion( "small intestine delta cell") +AnnotationAssertion(rdfs:label "type D cell of small intestine") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (type D cell of stomach) + +AnnotationAssertion(Annotation( "GOC:tfm") "A type D cell found in the stomach.") +AnnotationAssertion( ) +AnnotationAssertion( "2010-09-10T01:36:03Z") +AnnotationAssertion( "FMA:83410") +AnnotationAssertion( "delta cell of stomach") +AnnotationAssertion( "stomach D-cell") +AnnotationAssertion( "stomach delta cell") +AnnotationAssertion(rdfs:label "type D cell of stomach") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (histamine secreting cell) + +AnnotationAssertion(Annotation( "GOC:tfm") "A cell type that secretes histamine.") +AnnotationAssertion( ) +AnnotationAssertion( "2010-09-10T03:04:42Z") +AnnotationAssertion(rdfs:label "histamine secreting cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (pancreatic PP cell) + +AnnotationAssertion(Annotation( "GOC:tfm") "A PP cell located in the islets of the pancreas.") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( "2010-09-10T03:30:31Z") +AnnotationAssertion( "BTO:0000805") +AnnotationAssertion( "FMA:70588") +AnnotationAssertion( "MESH:D050418") +AnnotationAssertion( "PP cell of pancreatic islet") +AnnotationAssertion( "PP-cell of pancreatic islet") +AnnotationAssertion( "pancreatic polypeptide-secreting cell") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:comment "The term PP cell of pancreatic acinus was obsoleted due to a lack of evidence, making PP cell of pancreatic islets synonymous with pancreatic PP cell.") +AnnotationAssertion(rdfs:label "pancreatic PP cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + # Class: (type I cell of carotid body) AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "ISBN:0517223651") "A round or oval neuroepithelial cell that contacts other type I cells or capillaries. They occur in clusters that are surrounded by sheath cells (type-II cells) in the carotid body. This cell type is capable of secreting a number of neurotransmitters.") @@ -20477,6 +37135,7 @@ AnnotationAssertion( "epithelial reticular cell of thymus") AnnotationAssertion( "thymic epithelial cell") AnnotationAssertion(rdfs:label "epithelial cell of thymus") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) # Class: (type-1 epithelial cell of thymus) @@ -20489,6 +37148,64 @@ AnnotationAssertion(Annotation( "type-1 epithelial cell of thymus") SubClassOf( ) +# Class: (type B synovial cell) + +AnnotationAssertion(Annotation( ) Annotation( "GOC:tfm") Annotation( "ISBN:0517223651") Annotation( "PMID:34433485") Annotation( "PMID:34772990") "A resident stromal cell located in the synovial membrane and responsible for the production of immune-related cytokines and chemokines. This cell type secretes glycoproteins and hyaluronic acid, has abundant granular endoplasmic reticulum, but contains fewer vacuoles and vesicles.") +AnnotationAssertion( ) +AnnotationAssertion( "2010-09-13T03:39:14Z") +AnnotationAssertion( "BTO:0003652") +AnnotationAssertion( "FMA:66788") +AnnotationAssertion( "fibroblast-like synoviocyte") +AnnotationAssertion(Annotation( "PMID:23147896") "synovial fibroblast") +AnnotationAssertion(Annotation( "PMID:34433485") Annotation( "https://en.wikipedia.org/wiki/Fibroblast-like_synoviocyte") rdfs:comment "Type B synovial cells play a key role in the pathogenesis of chronic inflammatory diseases, such as rheumatoid arthritis, and are essential for the maintenance of normal joint functions. Fibroblast-like synoviocytes from different joints have different properties, which may contribute to the characteristic pattern of joint involvement in different types of arthritis.") +AnnotationAssertion(rdfs:label "type B synovial cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (epithelial cell of distal tubule) + +AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "ISBN:0517223651") "An epithelial cell of the distal convoluted tubule of the kidney that helps regulate systemic levels of potassium, sodium, calcium, and pH.") +AnnotationAssertion( "FMA:62125") +AnnotationAssertion( "FMA:70981") +AnnotationAssertion( "KUPO:0001055") +AnnotationAssertion( "kidney distal tubule epithelial cell") +AnnotationAssertion(rdfs:label "epithelial cell of distal tubule") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf(Annotation( "true") ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (epithelial cell of proximal tubule) + +AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "ISBN:1-4160-2328-3") "An epithelial cell of the proximal tubule of the kidney.") +AnnotationAssertion( ) +AnnotationAssertion( "FMA:62125") +AnnotationAssertion( "FMA:70973") +AnnotationAssertion( "KUPO:0001044") +AnnotationAssertion( "kidney proximal tubule epithelial cell") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "epithelial cell of proximal tubule") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf(Annotation( "true") ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (epithelial cell of skin gland) + +AnnotationAssertion(Annotation( "GOC:tfm") "An epithelial cell of a skin gland.") +AnnotationAssertion( ) +AnnotationAssertion( "2010-09-14T12:00:07Z") +AnnotationAssertion( "FMA:70657") +AnnotationAssertion( "epithelial cell of gland of skin") +AnnotationAssertion(rdfs:label "epithelial cell of skin gland") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + # Class: (somatotroph) AnnotationAssertion(Annotation( "SANBI:mhl") "An acidophilic cell of the anterior pituitary that produces growth hormone, somatotropin.") @@ -20506,7 +37223,6 @@ SubClassOf( (endocrine-paracrine cell of prostate gland) AnnotationAssertion(Annotation( "GOC:tfm") "An ecto-epithelial cell of the prostate gland that secretes hormones.") -AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( "2010-09-14T03:01:58Z") AnnotationAssertion( "CALOHA:TS-1280") @@ -20514,7 +37230,6 @@ AnnotationAssertion( "FMA:86774") AnnotationAssertion( "glandular cell of prostate") AnnotationAssertion( "neuro-epithelial cell of prostate gland") -AnnotationAssertion( ) AnnotationAssertion(rdfs:label "endocrine-paracrine cell of prostate gland") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf( ) @@ -20535,6 +37250,7 @@ AnnotationAssertion( "2010-09-14T03:31:44Z") AnnotationAssertion( "FMA:75607") AnnotationAssertion(rdfs:label "supporting cell of vestibular epithelium") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (neural cell) @@ -20544,9 +37260,7 @@ AnnotationAssertion( AnnotationAssertion( "CALOHA:TS-2040") AnnotationAssertion( "FMA:70333") AnnotationAssertion(rdfs:label "neural cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (connective tissue cell) @@ -20557,9 +37271,7 @@ AnnotationAssertion( "FMA:63875") AnnotationAssertion( "MESH:D003239") AnnotationAssertion(rdfs:label "connective tissue cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf(Annotation( "true") ) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (embryonic cell (metazoa)) @@ -20571,7 +37283,7 @@ AnnotationAssertion( "FMA:82841") AnnotationAssertion( "WBbt:0007028") AnnotationAssertion(rdfs:label "embryonic cell (metazoa)") -SubClassOf( ) +SubClassOf( ) # Class: (amniocyte) @@ -20593,23 +37305,43 @@ AnnotationAssertion( "FMA:67800") "basal cell of lactiferous duct") AnnotationAssertion( "myoepithelial cell of lactiferous gland") AnnotationAssertion(rdfs:label "myoepithelial cell of mammary gland") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -# Class: (mammary alveolar cell) +# Class: (lactocyte) -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:19022771") "The milk-producing cell of the alveolar unit that emerges during pregnancy.") +AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:19022771") Annotation( "PMID:28717367") Annotation( "PMID:35091553") Annotation( "PMID:35377806") Annotation( "doi:10.1177/156482659601700404") "A milk-producing glandular epithelial cell that is part of a mammary gland alveolus and differentiates from a luminal adaptive secretory precursor cell during secretory differentiation (also termed lactogenesis I). Following secretory activation (also termed lactogenesis II), a lactocyte is involved in the synthesis and/or transport of milk constituents including proteins, oligosaccharides, lactose, micronutrients, fat, hormones, immunoglobulins, and cytokines into the lumen of the lactating mammary gland.") +AnnotationAssertion( ) AnnotationAssertion( ) +AnnotationAssertion( ) AnnotationAssertion( "2010-09-20T01:30:57Z") +AnnotationAssertion(Annotation( "PMID:19022771") "mammary alveolar cell") AnnotationAssertion( "FMA:74506") AnnotationAssertion( "FMA:79866") AnnotationAssertion( "epithelial cell of lactiferous gland") +AnnotationAssertion(Annotation( "PMID:35091553") "lactaction-associated mammary epithelial cell") +AnnotationAssertion(Annotation( "PMID:35091553") "lactation-derived mammary cell") AnnotationAssertion( "luminal cell of alveolus of lactiferous gland") AnnotationAssertion( "mammary alveolar epithelial cell") AnnotationAssertion( "mammary gland alveolar epithelial cell") -AnnotationAssertion(rdfs:label "mammary alveolar cell") +AnnotationAssertion(Annotation( "PMID:35091553") Annotation( ) "LMC") +AnnotationAssertion(rdfs:label "lactocyte") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf(Annotation( "true") ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (luminal epithelial cell of mammary gland) + +AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:19022771") "A mammary epithelial cell that occurs in the lumen of the ductal and alveoli structure in the breast.") +AnnotationAssertion( ) +AnnotationAssertion( "2010-09-20T01:37:53Z") +AnnotationAssertion(Annotation( "PMID:21930782") "mature luminal cell") +AnnotationAssertion( "FMA:73280") +AnnotationAssertion(rdfs:label "luminal epithelial cell of mammary gland") +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) # Class: (mammary gland epithelial cell) @@ -20621,7 +37353,6 @@ AnnotationAssertion( "mammary epithelial cell") AnnotationAssertion(rdfs:label "mammary gland epithelial cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) # Class: (bronchial epithelial cell) @@ -20651,8 +37382,18 @@ AnnotationAssertion( "2010-09-20T02:21:12Z") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "ciliated cell of the bronchus") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (neural crest derived fat cell) + +AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:17507398") "A fat cell derived from a neural crest cell.") +AnnotationAssertion( ) +AnnotationAssertion( "2010-09-20T02:25:25Z") +AnnotationAssertion(rdfs:label "neural crest derived fat cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (preadipocyte) AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:18793119") "An undifferentiated fibroblast that can be stimulated to form a fat cell.") @@ -20721,7 +37462,6 @@ AnnotationAssertion( AnnotationAssertion( "pancreatic endocrine progenitor") AnnotationAssertion( "pancreatic islet progenitor cell") AnnotationAssertion(rdfs:label "progenitor cell of endocrine pancreas") -SubClassOf( ) SubClassOf( ) # Class: (gestational hematopoietic stem cell) @@ -20775,6 +37515,21 @@ AnnotationAssertion(rdfs:label "cere SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (keratocyte) + +AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "ISBN:978-0-7020-2958-5") "A keratocyte is a specialized fibroblast residing in the cornea stroma that has a flattened, dendritic cell located between the lamellae with a large flattened nucleus and lengthy processes which communicate with neighboring cells. This corneal layer, representing about 85-90% of corneal thickness, is built up from highly regular collagenous lamellae and extracellular matrix components. Keratocytes play the major role in keeping it transparent, healing its wounds, and synthesizing its components. This cell type secretes collagen I, V, VI, and keratin sulfate.") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( "2010-09-22T01:57:40Z") +AnnotationAssertion( "corneal fibroblast") +AnnotationAssertion( "corneal keratocyte") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "keratocyte") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (cortical thymic epithelial cell) AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:18403190") "An epithelial cell of the cortical portion of the thymus. Epithelial cells in this region are required for positive selection of CD8-positive T cells.") @@ -20785,8 +37540,30 @@ AnnotationAssertion( "cTEC") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "cortical thymic epithelial cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (medullary thymic epithelial cell) + +AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:18180458") "An epithelial cell of the medullary thymus. This cell type expresses a diverse range of tissue-specific antigens. This promiscuous gene expression is a cell-autonomous property of medullary epithelial cells and is maintained during the entire period of thymic T cell output.") +AnnotationAssertion( ) +AnnotationAssertion( "2010-09-23T03:17:14Z") +AnnotationAssertion( "BTO:0004563") +AnnotationAssertion( "mTEC") +AnnotationAssertion(rdfs:label "medullary thymic epithelial cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (myometrial cell) + +AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:11429640") "A smooth muscle cell of the myometrium that enlarges and stretches during pregnancy, and contracts in response to oxytocin.") +AnnotationAssertion( ) +AnnotationAssertion( "2010-09-23T03:46:34Z") +AnnotationAssertion( "BTO:0004519") +AnnotationAssertion( "myometrium smooth muscle cell") +AnnotationAssertion(rdfs:label "myometrial cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (trabecular meshwork cell) AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:14500801") "A cell that lines the trabecular meshwork, which is an area of tissue in the eye located around the base of the cornea, near the ciliary body, and is responsible for draining the aqueous humor from the eye via the anterior chamber (the chamber on the front of the eye covered by the cornea). This cell may play a role in regulating intraocular pressure.") @@ -20794,6 +37571,7 @@ AnnotationAssertion( "2010-09-23T04:18:50Z") AnnotationAssertion( "trabeculocyte") AnnotationAssertion(rdfs:label "trabecular meshwork cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) # Class: (respiratory epithelial cell) @@ -20804,6 +37582,7 @@ AnnotationAssertion( AnnotationAssertion( "BTO:0004533") AnnotationAssertion( "airway epithelial cell") AnnotationAssertion(rdfs:label "respiratory epithelial cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) # Class: (respiratory goblet cell) @@ -20816,19 +37595,6 @@ AnnotationAssertion(rdfs:label "resp EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (somatic cell) - -AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "ISBN:0721662544") "A cell of an organism that does not pass on its genetic material to the organism's offspring (i.e. a non-germ line cell).") -AnnotationAssertion( ) -AnnotationAssertion( "2010-09-24T09:44:42Z") -AnnotationAssertion( "BTO:0001268") -AnnotationAssertion( "FMA:72300") -AnnotationAssertion( "WBbt:0008378") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "somatic cell") -SubClassOf( ) -SubClassOf( ) - # Class: (myotube) AnnotationAssertion(Annotation( "GOC:dos") Annotation( "GOC:tfm") Annotation( "ISBN:0323052908") Annotation( "PMID:22274696") "A transversely striated, synctial muscle cell, formed by the fusion of myoblasts.") @@ -20857,7 +37623,6 @@ AnnotationAssertion( AnnotationAssertion( "Schwann cell precursor cell") AnnotationAssertion(rdfs:label "Schwann cell precursor") SubClassOf( ) -SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) # Class: (immature Schwann cell) @@ -20941,6 +37706,7 @@ AnnotationAssertion( "immature T-cell") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "immature T cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) # Class: (nucleated reticulocyte) @@ -20987,8 +37753,8 @@ AnnotationAssertion( AnnotationAssertion(Annotation( "PMID:2253328") "oligodendrocyte-type 2 astrocyte (O-2A) progenitor cell") AnnotationAssertion(Annotation( ) Annotation( "PMID:24133281") "oligodendrocyte/type-2 astrocyte progenitor cell") AnnotationAssertion( "MESH:D000073637") -AnnotationAssertion(Annotation( "PMID:24133281") Annotation( ) "O-2A/OPC") -AnnotationAssertion(Annotation( "PMID:11756508") Annotation( ) "O2A/OPC") +AnnotationAssertion(Annotation( "PMID:24133281") Annotation( ) "O-2A/OPC") +AnnotationAssertion(Annotation( "PMID:11756508") Annotation( ) "O2A/OPC") AnnotationAssertion( ) AnnotationAssertion(Annotation( "ISBN:9780702028991") Annotation( "PMID:10704434") Annotation( "PMID:2182078") rdfs:comment "This cell type can be purified from optic nerves and other regions of the embryonic, postnatal and adult rat CNS and can be differentiated in vitro to oligodendrocytes and type-2 astrocytes. Some references use the terms 'oligodendrocyte precursor cell' and 'oligodendrocyte type-2 astrocyte (O-2A) progenitor' to refer to the same entity (e.g., PMID:10704434), while others describe an oligodendrocyte type-2 astrocyte (O-2A) progenitor cell as the precurosr to oligodendrocyte- and type-2 astrocyte- progenitor cells (e.g, ISBN:9780702028991).") AnnotationAssertion(rdfs:label "oligodendrocyte precursor cell") @@ -21105,8 +37871,6 @@ AnnotationAssertion( "2010-12-03T03:17:05Z") AnnotationAssertion(rdfs:label "dermal melanocyte") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) # Class: (hair follicle melanocyte) @@ -21116,7 +37880,6 @@ AnnotationAssertion( AnnotationAssertion(rdfs:label "hair follicle melanocyte") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) -SubClassOf( ) # Class: (epithelial melanocyte) @@ -21127,7 +37890,6 @@ AnnotationAssertion(rdfs:comment "Th AnnotationAssertion(rdfs:label "epithelial melanocyte") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) -SubClassOf( ) # Class: (retinal melanocyte) @@ -21137,8 +37899,6 @@ AnnotationAssertion( AnnotationAssertion( ) AnnotationAssertion(rdfs:label "retinal melanocyte") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) # Class: (strial intermediate cell) @@ -21180,9 +37940,7 @@ AnnotationAssertion( "heart cell") AnnotationAssertion(rdfs:comment "From Onard of the FMA: Cardiac muscle cell or cardiac myocyte is a striated muscle cell. Cardiocyte on the other hand is any cell in the heart which includes cells other than muscle cells (e.g. endothelial cell of endocardium). Unless there is a consensus among anatomists that cardiocytes refer only to muscle cells, we will treat them as a general class of cells in the heart.") AnnotationAssertion(rdfs:label "cardiocyte") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf(Annotation( "true") ) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (spongiotrophoblast cell) @@ -21194,6 +37952,37 @@ AnnotationAssertion(rdfs:label "spon SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (adventitial cell) + +AnnotationAssertion(Annotation( "GOC:tfm") "A cell of the adventitial layer of ductal structures such as the uterer, defent duct, biliary duct, etc") +AnnotationAssertion( ) +AnnotationAssertion( "2010-12-07T04:03:56Z") +AnnotationAssertion( "BTO:0002441") +AnnotationAssertion( "FMA:84639") +AnnotationAssertion(rdfs:label "adventitial cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (enteric smooth muscle cell) + +AnnotationAssertion(Annotation( "GOC:tfm") "A smooth muscle cell of the intestine.") +AnnotationAssertion( ) +AnnotationAssertion( "2011-01-17T03:39:38Z") +AnnotationAssertion( "intestinal smooth muscle cell") +AnnotationAssertion(rdfs:label "enteric smooth muscle cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) + +# Class: (langerin-positive lymph node dendritic cell) + +AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "http://www.immgen.org/index_content.html") "A dermal dendritic cell isolated from skin draining lymph nodes that is langerin-positive, MHC-II-positive, and CD4-negative and CD8a-negative.") +AnnotationAssertion( ) +AnnotationAssertion( "2011-01-21T01:57:00Z") +AnnotationAssertion(rdfs:label "langerin-positive lymph node dendritic cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) + # Class: (kidney epithelial cell) AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "KUPO:SJ") "An epithelial cell of the kidney.") @@ -21201,8 +37990,21 @@ AnnotationAssertion( "2011-02-08T10:46:34Z") AnnotationAssertion( "KUPO:0001019") AnnotationAssertion(rdfs:label "kidney epithelial cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) +# Class: (subcutaneous fat cell) + +AnnotationAssertion(Annotation( "GOC:tfm") "A fat cell that is part of subcutaneous adipose tissue.") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( "2011-02-21T02:51:22Z") +AnnotationAssertion( "subcutaneous adipocyte") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "subcutaneous fat cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) + # Class: (renal filtration cell) AnnotationAssertion(Annotation( "GOC:tfm") "A renal filtration cell is a specialized cell of the renal system that filter fluids by charge, size or both.") @@ -21251,8 +38053,6 @@ AnnotationAssertion(Annotation( "GOC:tfm") "uterine cervix epithelial cell") AnnotationAssertion(rdfs:label "epithelial cell of cervix") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) # Class: (epithelial cell of amnion) @@ -21265,8 +38065,6 @@ AnnotationAssertion( ) AnnotationAssertion(rdfs:label "epithelial cell of amnion") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) # Class: (amnion mesenchymal stem cell) @@ -21308,8 +38106,10 @@ EquivalentClasses( ObjectIntersection # Class: (chorionic membrane mesenchymal stem cell) AnnotationAssertion(Annotation( "GOC:tfm") "A mesenchymal stem cell of the chorionic membrane.") +AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( "2011-02-28T03:04:35Z") +AnnotationAssertion( ) AnnotationAssertion(rdfs:label "chorionic membrane mesenchymal stem cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) @@ -21336,7 +38136,6 @@ AnnotationAssertion( AnnotationAssertion(rdfs:comment "See CL:0002619.") AnnotationAssertion(rdfs:label "embryonic blood vessel endothelial progenitor cell") SubClassOf( ) -SubClassOf( ) # Class: (fibroblast of the aortic adventitia) @@ -21395,12 +38194,10 @@ SubClassOf(Annotation( # Class: (fibroblast of lung) AnnotationAssertion(Annotation( "GOC:tfm") "A fibroblast that is part of lung.") -AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( "2011-02-28T05:11:03Z") AnnotationAssertion( "BTO:0000764") AnnotationAssertion( "CALOHA:TS-0575") -AnnotationAssertion( ) AnnotationAssertion(rdfs:label "fibroblast of lung") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) @@ -21435,8 +38232,10 @@ SubClassOf(Annotation( # Class: (fibroblast of pulmonary artery) AnnotationAssertion(Annotation( "GOC:tfm") "A fibroblast of pulmonary artery.") +AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( "2011-02-28T05:22:27Z") +AnnotationAssertion( ) AnnotationAssertion(rdfs:label "fibroblast of pulmonary artery") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) @@ -21447,9 +38246,7 @@ AnnotationAssertion(Annotation( ) AnnotationAssertion( "2011-03-01T04:11:01Z") AnnotationAssertion(rdfs:label "hair follicle cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf(Annotation( "true") ) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (inner root sheath cell) @@ -21459,7 +38256,6 @@ AnnotationAssertion( AnnotationAssertion(rdfs:label "inner root sheath cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -SubClassOf(Annotation( "true") ) SubClassOf(Annotation( "true") ) # Class: (outer root sheath cell) @@ -21469,8 +38265,6 @@ AnnotationAssertion( "2011-03-01T04:29:47Z") AnnotationAssertion(rdfs:label "outer root sheath cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) SubClassOf(Annotation( "true") ) # Class: (hair germinal matrix cell) @@ -21579,7 +38373,6 @@ AnnotationAssertion( AnnotationAssertion(rdfs:label "placental epithelial cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) # Class: (mesenteric preadipocyte) @@ -21657,9 +38450,7 @@ AnnotationAssertion( ) AnnotationAssertion(rdfs:label "retinal pigment epithelial cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) SubClassOf( ) -SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) # Class: (smooth muscle cell of the umbilical vein) @@ -21692,9 +38483,11 @@ SubClassOf(Annotation( # Class: (smooth muscle cell of the pulmonary artery) AnnotationAssertion(Annotation( "GOC:tfm") "A smooth muscle of the pulmonary artery.") +AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( "2011-03-06T05:01:28Z") AnnotationAssertion( "BTO:0003336") +AnnotationAssertion( ) AnnotationAssertion(rdfs:label "smooth muscle cell of the pulmonary artery") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) @@ -21766,6 +38559,7 @@ AnnotationAssertion( AnnotationAssertion( "BTO:0004402") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "bronchial smooth muscle cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) # Class: (smooth muscle cell of the esophagus) @@ -21971,8 +38765,6 @@ AnnotationAssertion( "2011-03-14T12:46:28Z") AnnotationAssertion(rdfs:label "gingival epithelial cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) # Class: (prostate stromal cell) @@ -21999,14 +38791,24 @@ AnnotationAssertion(Annotation( ) AnnotationAssertion( "2011-03-15T11:59:23Z") AnnotationAssertion(rdfs:label "seminiferous tubule epithelial cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (epithelial cell of upper respiratory tract) + +AnnotationAssertion( ) +AnnotationAssertion( "2011-06-21T12:28:55Z") +AnnotationAssertion(rdfs:label "epithelial cell of upper respiratory tract") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) + # Class: (epithelial cell of lower respiratory tract) AnnotationAssertion( ) AnnotationAssertion( "2011-06-21T12:29:31Z") AnnotationAssertion(rdfs:label "epithelial cell of lower respiratory tract") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) # Class: (epithelial cell of anal column) @@ -22016,8 +38818,6 @@ AnnotationAssertion( "2011-07-08T12:11:38Z") AnnotationAssertion(rdfs:label "epithelial cell of anal column") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) # Class: (keratinized epithelial cell of the anal canal) @@ -22094,6 +38894,7 @@ AnnotationAssertion( AnnotationAssertion( "CALOHA:TS-1284") AnnotationAssertion( "FMA:86554") AnnotationAssertion(rdfs:label "glandular cell of stomach") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) # Class: (myocardial endocrine cell of atrium) @@ -22112,7 +38913,7 @@ AnnotationAssertion(Annotation( ) AnnotationAssertion( "2011-07-11T03:15:38Z") AnnotationAssertion(Annotation( "PMID:17519333") Annotation( "PMID:19745164") "cardiovascular progenitor cell") -AnnotationAssertion(Annotation( "PMID:19745164") Annotation( ) "CPC") +AnnotationAssertion(Annotation( "PMID:19745164") Annotation( ) "CPC") AnnotationAssertion(rdfs:comment "Discrepancy in develops from origins prevents me from making the assertion that cardioblasts give rise to all instances of cardiocytes as we state cardiac muscle cells develop from cardiac myoblast, which in turn develop from muscle stem cell.") AnnotationAssertion(rdfs:label "cardioblast") SubClassOf( ) @@ -22135,6 +38936,32 @@ AnnotationAssertion(rdfs:label "reti SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (tongue muscle cell) + +AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:18816858") "A skeletal muscle cell that is part of the tongue.") +AnnotationAssertion( ) +AnnotationAssertion( "2011-08-16T03:10:02Z") +AnnotationAssertion(rdfs:label "tongue muscle cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (neural crest derived neuroblast) + +AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:17407019") "A neuroblast derived from a neural crest cell.") +AnnotationAssertion( ) +AnnotationAssertion( "2011-08-22T09:24:15Z") +AnnotationAssertion(rdfs:label "neural crest derived neuroblast") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (PP cell of intestine) + +AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "PMID:2420136") Annotation( "PMID:728970") "A PP cell found in intestine.") +AnnotationAssertion( ) +AnnotationAssertion( "2011-09-27T11:59:01Z") +AnnotationAssertion(rdfs:label "PP cell of intestine") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) + # Class: (kidney cortical cell) AnnotationAssertion( "A cell that is part of a cortex of kidney.") @@ -22142,13 +38969,13 @@ AnnotationAssertion( "2011-10-25T03:49:41Z") AnnotationAssertion(rdfs:label "kidney cortical cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) # Class: (spinal cord interneuron) AnnotationAssertion(Annotation( "CL:CVS") "A CNS interneuron located in the spinal cord.") AnnotationAssertion(rdfs:comment "Is_a interneuron, part_of UBERON:0002240.") AnnotationAssertion(rdfs:label "spinal cord interneuron") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) # Class: (ionocyte) @@ -22158,7 +38985,6 @@ AnnotationAssertion( ) AnnotationAssertion(rdfs:label "ionocyte") SubClassOf( ) -SubClassOf( ) # Class: (macular hair cell) @@ -22185,6 +39011,43 @@ AnnotationAssertion(rdfs:label "mult SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (auditory epithelial supporting cell) + +AnnotationAssertion(Annotation( "CL:CVS") Annotation( "GOC:tfm") "A non-sensory cell that extends from the basement membrane to the apical surface of the auditory epithelium and provides support for auditory hair cells.") +AnnotationAssertion( "auditory epithelial support cell") +AnnotationAssertion(rdfs:label "auditory epithelial supporting cell") +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (lymphangioblast) + +AnnotationAssertion(Annotation( "CL:CVS") "Lymphatic progenitor cells.") +AnnotationAssertion( ) +AnnotationAssertion( "2012-01-12T04:44:34Z") +AnnotationAssertion(rdfs:comment "Usually express Prox1, or prox1b.") +AnnotationAssertion(rdfs:label "lymphangioblast") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) + +# Class: (vascular lymphangioblast) + +AnnotationAssertion(Annotation( "CL:CVS") "Lymphatic progenitor cells, derived from the veins, that give rise to lymphatic endothelial cells.") +AnnotationAssertion( ) +AnnotationAssertion( "2012-01-12T05:21:09Z") +AnnotationAssertion( "parachordal lymphangioblast") +AnnotationAssertion(rdfs:label "vascular lymphangioblast") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) + +# Class: (somatomotor neuron) + +AnnotationAssertion(Annotation( "ZFIN:CVS") "A motor neuron that innervates a skeletal muscle. These motor neurons are all excitatory and cholinergic.") +AnnotationAssertion( "somatic motor neuron") +AnnotationAssertion(rdfs:label "somatomotor neuron"@en) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (hepatoblast) AnnotationAssertion(Annotation( "GOC:CVS") Annotation( "PMID:18356246") Annotation( "PMID:20483998") Annotation( "PMID:26798363") Annotation( "https://orcid.org/0000-0003-1940-6740") "Multi fate stem cell that gives rise to both hepatocytes and cholangiocytes as descendants. The term often refers to fetal precursors of hepatocytes (differently from 'hepatic stem cell', usually applied to the self-renewing pool of hepatocyte precursors in the adult liver). Hepatoblasts may also be endogenous, as some stem cells found in the liver come from the bone marrow via blood circulation.") @@ -22263,6 +39126,17 @@ SubClassOf( ObjectSomeValuesFrom( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (enteric neuron) + +AnnotationAssertion(Annotation( "CL:MAH") "Neuron that is part of the enteric nervous system.") +AnnotationAssertion( ) +AnnotationAssertion( "2012-06-28T08:20:31Z") +AnnotationAssertion(rdfs:label "enteric neuron") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (non-striated muscle cell) AnnotationAssertion(Annotation( "GOC:DOS") "Any muscle cell in which the fibers are not organised into sarcomeres.") @@ -22280,12 +39154,14 @@ SubClassOf( "GOC:tfm") Annotation( "ISBN:0323052908") "A transversely striated, synctial cell of skeletal muscle. It is formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.") AnnotationAssertion( "MESH:D018485") AnnotationAssertion(rdfs:label "skeletal muscle fiber"@en) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf( ObjectSomeValuesFrom( )) # Class: (somatic muscle myotube) AnnotationAssertion(Annotation( "PMID:22274696") Annotation( "PMID:8720463") "A myotube that is part of some somatic muscle. Examples include arthropod somatic muscle cells.") AnnotationAssertion(rdfs:label "somatic muscle myotube") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) # Class: (somatic muscle cell) @@ -22298,6 +39174,7 @@ SubClassOf( "PMID:8720463") "A somatic muscle cell that is oblquely striated. Examples include the somatic muscles of nematodes.") AnnotationAssertion(rdfs:label "obliquely striated somatic muscle cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf( ) # Class: (visceral muscle cell) @@ -22326,15 +39203,12 @@ AnnotationAssertion(Annotation( "The vast majority of these cells develop from skeletal muscle satellite cells, although there are some reports of other origins.") AnnotationAssertion(rdfs:label "adult skeletal muscle myoblast") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) -SubClassOf( ) # Class: (somatic muscle myoblast) AnnotationAssertion( "A myoblast that is commited to developing into a somatic muscle.") AnnotationAssertion(rdfs:label "somatic muscle myoblast") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) # Class: (mesenchymal cell) @@ -22366,7 +39240,6 @@ AnnotationAssertion( "pancreatic endocrine cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -SubClassOf( ) # Class: (noradrenergic neuron) @@ -22417,6 +39290,14 @@ AnnotationAssertion( "mural cell"@en) SubClassOf( ) +# Class: (microcirculation associated smooth muscle cell) + +AnnotationAssertion( ) +AnnotationAssertion( "2020-02-29T17:37:00Z"^^xsd:dateTime) +AnnotationAssertion(rdfs:label "microcirculation associated smooth muscle cell"@en) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + # Class: (alpha motor neuron) AnnotationAssertion(Annotation( "DOI:10.1016/B978-0-12-801238-3.05364-2") Annotation( "Wikipedia:Alpha_motor_neuron&oldid=957148643") "A large, multipolar lower motor neuron of the brainstem and spinal cord that innervates the extrafusal muscle fibers of skeletal muscle and are directly responsible for initiating their contraction. While their cell bodies are in the CNS (in the anterior gray horn of the spinal cord), they are part of the somatic nervous system - a branch of the PNS.") @@ -22475,8 +39356,6 @@ AnnotationAssertion( "PMID:12021768") AnnotationAssertion(rdfs:label "compound eye retinal cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))))) -SubClassOf( ) -SubClassOf( ) # Class: (retinal cell) @@ -22484,6 +39363,7 @@ AnnotationAssertion(Annotation( "PMID:10702418") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "retinal cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) # Class: (enteroendocrine cell of small intestine) @@ -22957,11 +39837,13 @@ EquivalentClasses( ObjectIntersection # Class: (epithelial cell of endometrial gland) AnnotationAssertion(Annotation( "https://orcid.org/0000-0003-3440-1876") Annotation( "https://orcid.org/0000-0003-4183-8865") "An epithelial cell that is part of an endometrial gland.") +AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( "2021-11-30T16:13:30Z"^^xsd:dateTime) AnnotationAssertion( "EFO:0010710") AnnotationAssertion( "endometrial glandular epithelial cell") AnnotationAssertion( ) +AnnotationAssertion( ) AnnotationAssertion(rdfs:label "epithelial cell of endometrial gland") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) @@ -22990,6 +39872,7 @@ AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "lung pericyte") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (Leydig stem cell) @@ -23064,20 +39947,34 @@ EquivalentClasses( ObjectIntersection # Class: (hepatic portal fibroblast) AnnotationAssertion(Annotation( "PMID:20209607") Annotation( "PMID:24814904") Annotation( "https://orcid.org/0000-0001-7655-4833") "A fibroblast located in the portal triad. Hepatic portal fibroblast are a non-parenchymal cell population located adjacent to bile duct epithelia in liver and are distinct from stellate cells. They differentiate into fibrogenic myofibroblasts during chronic injury states producing high levels of collagen.") +AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( "2022-03-17T12:00:44Z"^^xsd:dateTime) AnnotationAssertion( "portal fibroblast") +AnnotationAssertion( ) AnnotationAssertion(rdfs:label "hepatic portal fibroblast") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (lymph node lymphatic vessel endothelial cell) AnnotationAssertion(Annotation( "https://orcid.org/0000-0001-7655-4833") "An endothelial cell located in a lymph node lymphatic vessel.") +AnnotationAssertion( ) AnnotationAssertion( ) +AnnotationAssertion( ) AnnotationAssertion(rdfs:label "lymph node lymphatic vessel endothelial cell") AnnotationAssertion(rdfs:seeAlso "https://github.com/obophenotype/cell-ontology/issues/1472") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +# Class: (progenitor cell of mammary luminal epithelium) + +AnnotationAssertion(Annotation( "PMID:19063729") Annotation( "PMID:20346151") Annotation( "PMID:21930782") Annotation( "https://orcid.org/0000-0003-4412-7970") "A progenitor cell with the potential to differentiate into luminal epithelial cells of mammary glands. In mouse, CD61 and c-kit were found to be coexpressed by the majority of, but not all, committed luminal progenitor cells.") +AnnotationAssertion( ) +AnnotationAssertion( "luminal progenitor cell") +AnnotationAssertion( "progenitor cell of luminal mammary epithelium") +AnnotationAssertion(rdfs:label "progenitor cell of mammary luminal epithelium") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (stromal cell of bone marrow) AnnotationAssertion( "A stromal cell that is part_of a bone marrow.") @@ -23117,8 +40014,7 @@ EquivalentClasses( ObjectIntersection AnnotationAssertion(Annotation( "GOC:mtg_heart") "A specialized cardiomyocyte that transmit signals from the AV node to the cardiac Purkinje fibers.") AnnotationAssertion( "AV bundle cell") AnnotationAssertion(rdfs:label "atrioventricular bundle cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (cardiac blood vessel endothelial cell) @@ -23128,8 +40024,7 @@ EquivalentClasses( ObjectIntersection # Class: (His-Purkinje system cell) AnnotationAssertion(rdfs:label "His-Purkinje system cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (cardiac endothelial cell) @@ -23142,6 +40037,32 @@ EquivalentClasses( ObjectIntersection AnnotationAssertion( "camera type eye photoreceptor cell") AnnotationAssertion(rdfs:label "camera-type eye photoreceptor cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (cerebellar stellate cell) + +AnnotationAssertion(rdfs:label "cerebellar stellate cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (cerebral cortex GABAergic interneuron) + +AnnotationAssertion(Annotation( "GOC:dos") "A GABAergic interneuron whose soma is located in the cerebral cortex.") +AnnotationAssertion(rdfs:label "cerebral cortex GABAergic interneuron") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (cerebral cortex neuron) + +AnnotationAssertion(Annotation( "GOC:tfm") "A CNS neuron of the cerebral cortex.") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( "BTO:0004102") +AnnotationAssertion( "FMA:84104") +AnnotationAssertion( "cortical neuron") +AnnotationAssertion( "neuron of cerebral cortex") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "cerebral cortex neuron") +AnnotationAssertion(rdfs:seeAlso "https://github.com/obophenotype/cell-ontology/issues/1359") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (coronet cell) @@ -23156,7 +40077,7 @@ AnnotationAssertion( "MESH:D015053") AnnotationAssertion(rdfs:label "zygote"@en) AnnotationAssertion(rdfs:seeAlso ) -SubClassOf( ) +SubClassOf( ) # Class: (cardiac glial cell) @@ -23168,7 +40089,6 @@ EquivalentClasses( ObjectIntersection AnnotationAssertion( "MESH:D032386") AnnotationAssertion(rdfs:label "cardiac myoblast") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) # Class: (cardiac neuron) @@ -23222,8 +40142,19 @@ AnnotationAssertion( ) AnnotationAssertion(rdfs:comment "The formal and textual definitions of this term will need to be altered if evidence for non-inhibitory GABA-ergic neurons emerges.") AnnotationAssertion(rdfs:label "GABAergic interneuron") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (paraxial cell) + +AnnotationAssertion(Annotation( "GOC:NV") Annotation( "PMID:11687492") "A cell in the area of mesoderm in the neurulating embryo that flanks and forms simultaneously with the neural tube. The cells of this region give rise to somites.") +AnnotationAssertion( "paraxial mesoderm cell") +AnnotationAssertion( "somitic mesoderm cell") +AnnotationAssertion( "presomitic mesoderm cell") +AnnotationAssertion(rdfs:label "paraxial cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + # Class: (neural crest cell) AnnotationAssertion(Annotation( "https://orcid.org/0000-0001-5208-3432") Annotation( "https://orcid.org/0000-0002-9900-7880") "A cell of the neural crest. Neural crest cells are multipotent. Premigratory neural crest cells are found at the neural plate boarder, some of which will undergo ectomesynchymal transition and delamination to form migratory neural crest cells.") @@ -23237,8 +40168,6 @@ AnnotationAssertion(Annotation( ) AnnotationAssertion(rdfs:label "motile sperm cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) -SubClassOf( ) # Class: (flagellated sperm cell) @@ -23246,7 +40175,6 @@ AnnotationAssertion(Annotation( ) AnnotationAssertion(rdfs:label "flagellated sperm cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) SubClassOf( ) # Class: (mesothelial cell of epicardium) @@ -23278,8 +40206,34 @@ SubClassOf( "ISBN:978-1-62808-994-3") Annotation( "https://doi.org/10.1016/B978-0-12-409503-8.00002-0") "A precursor cell that has a tendency to differentiate into a specific type of cell. They are descendants of stem cells, only they are more constrained in their differentiation potential or capacity for self-renewal, and are often more limited in both senses.") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "progenitor cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (skeletal muscle fibroblast) + +AnnotationAssertion(Annotation( "PMID:28369879") Annotation( "https://orcid.org/0000-0001-6164-0667") "Any fibroblast that is part of skeletal muscle tissue.") +AnnotationAssertion( ) +AnnotationAssertion( "skeleton muscle fibroblast") +AnnotationAssertion(rdfs:label "skeletal muscle fibroblast") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (dermal microvascular endothelial cell) + +AnnotationAssertion(Annotation( "BTO:0004574") Annotation( "CL:patterns/cellPartOfAnatomicalEntity") "Any microvascular endothelial cell that is part of the dermis.") +AnnotationAssertion( ) +AnnotationAssertion( "DMEC cell") +AnnotationAssertion( "dermal microvascular endothelium cell") +AnnotationAssertion(rdfs:label "dermal microvascular endothelial cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (chorionic trophoblast cell) + +AnnotationAssertion(Annotation( "GOC:NV") "Cells of the uterine chorion that acquire specialized structural and/or functional features that characterize chorionic trophoblasts. These cells will migrate towards the spongiotrophoblast layer and give rise to syncytiotrophoblasts of the labyrinthine layer.") +AnnotationAssertion(rdfs:label "chorionic trophoblast cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + # Class: (sympathetic neuron) AnnotationAssertion(Annotation( "GOC:NV") Annotation( "isbn:0080923437") "Sympathetic neurons are part of the sympathetic nervous system and are primarily adrenergic producing the neurotransmitter noradrenalin along with other neuropeptides.") @@ -23288,13 +40242,27 @@ AnnotationAssertion( "sympathetic neuron") SubClassOf( ) +# Class: (colon epithelial cell) + +AnnotationAssertion(Annotation( "GOC:NV") "Epithelial cell that is part of the colon epithelium.") +AnnotationAssertion( "colonic epithelial cell") +AnnotationAssertion(rdfs:label "colon epithelial cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (spiral ganglion neuron) + +AnnotationAssertion(Annotation( "GOC:NV") "Neuron found in the spiral ganglion.") +AnnotationAssertion(rdfs:label "spiral ganglion neuron") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + # Class: (precursor cell) AnnotationAssertion(Annotation( "GOC:dos") "A cell that, by division or terminal differentiation, can give rise to other cell types.") AnnotationAssertion(rdfs:comment "Work is needed on GO 'cell differentiation' before it is clear whether the equivalent class definition 'native cell' that capable_of some 'cell differentiation' works. Also, may want to consider merging this with non-terminally differentiated cell.") AnnotationAssertion(rdfs:label "precursor cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (astrocyte of the forebrain) @@ -23337,9 +40305,11 @@ SubClassOf( (prostate neuroendocrine cell) AnnotationAssertion(Annotation( "PMID:33842835") Annotation( "http://orcid.org/0000-0001-7772-9578") "A neuroendocrine cell that is part of the prostate epithelium.") +AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( "neuroendocrine cell of prostate epithelium") AnnotationAssertion( "neuroendocrine cell of the prostate") +AnnotationAssertion( ) AnnotationAssertion(rdfs:label "prostate neuroendocrine cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) @@ -23410,7 +40380,6 @@ AnnotationAssertion( ) AnnotationAssertion(rdfs:label "tracheobronchial serous cell"@en) EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) # Class: (tracheobronchial chondrocyte) @@ -23427,10 +40396,12 @@ EquivalentClasses( ObjectIntersection # Class: (tracheobronchial goblet cell) AnnotationAssertion( "Any goblet cell that is part of the tracheobronchial epithelium.") +AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( "2020-05-07T18:14:52Z"^^xsd:dateTime) AnnotationAssertion( "goblet cell of tracheobronchial tree") AnnotationAssertion( ) +AnnotationAssertion( ) AnnotationAssertion(rdfs:label "tracheobronchial goblet cell"@en) EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) @@ -23465,6 +40436,126 @@ AnnotationAssertion( "smooth muscle cell of tracheobronchial tree") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "tracheobronchial smooth muscle cell"@en) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (extrahepatic cholangiocyte) + +AnnotationAssertion(Annotation( "PMID:23720296") "An epithelial cell of the extrahepatic bile ducts, including the left and right hepatic duct, common hepatic duct, and common bile duct. They are columnar in shape, and have a large nuclear-to-cytoplasmic ratio relative to small/intrahepatic cholangiocytes.") +AnnotationAssertion( ) +AnnotationAssertion( "2020-09-03T12:24:24Z"^^xsd:dateTime) +AnnotationAssertion(Annotation( "PMID:23720296") "large bile duct cholangiocyte") +AnnotationAssertion(rdfs:label "extrahepatic cholangiocyte"@en) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (endothelial cell of periportal hepatic sinusoid) + +AnnotationAssertion(Annotation( "PMID:27423426") "An endothelial cell found in the periportal region hepatic sinusoid, near the portal triad. The fenestrae of these cells are larger but fewer in number compared with those of endothelial cells near the centrilobular region of the hepatic sinusoid.") +AnnotationAssertion( ) +AnnotationAssertion( "2020-09-09T13:56:47Z"^^xsd:dateTime) +AnnotationAssertion( "EFO:0010705") +AnnotationAssertion(Annotation( "PMID:28287163") "periportal LSEC") +AnnotationAssertion(Annotation( "PMID:30348985") "periportal hepatic sinusoidal endothelial cell") +AnnotationAssertion(rdfs:label "endothelial cell of periportal hepatic sinusoid"@en) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (endothelial cell of pericentral hepatic sinusoid) + +AnnotationAssertion(Annotation( "PMID:27423426") "An endothelial cell found in the centrilobular region hepatic sinusoid, near the central vein. The fenestrae of these cells are smaller but more numerous compared with those of endothelial cells near the periportal region of the hepatic sinusoid.") +AnnotationAssertion( ) +AnnotationAssertion( "2020-09-10T12:38:29Z"^^xsd:dateTime) +AnnotationAssertion( "EFO:0010706") +AnnotationAssertion(Annotation( "PMID:30348985") "central venous hepatic sinusoidal endothelial cell") +AnnotationAssertion(Annotation( "PMID:28287163") "pericentral LSEC") +AnnotationAssertion(rdfs:label "endothelial cell of pericentral hepatic sinusoid"@en) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (periportal region hepatocyte) + +AnnotationAssertion(Annotation( "PMID:29763190") "Any hepatocyte that is part of the liver lobule periportal region. These cells are primarily involved in oxidative energy metabolism.") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( "2020-10-12T10:29:31Z"^^xsd:dateTime) +AnnotationAssertion(Annotation( "PMID:29763190") "periportal hepatocyte") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "periportal region hepatocyte"@en) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (midzonal region hepatocyte) + +AnnotationAssertion(Annotation( "PMID:29763190") "Any hepatocyte that is part of the liver lobule midzonal region. These cells have mixed functionality in comparison with those in the other two regions of the liver lobule.") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( "2020-10-12T10:57:40Z"^^xsd:dateTime) +AnnotationAssertion(Annotation( "PMID:29763190") "midzonal hepatocyte") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "midzonal region hepatocyte"@en) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (centrilobular region hepatocyte) + +AnnotationAssertion(Annotation( "PMID:29763190") "Any hepatocyte that is part of the liver lobule centrilobular region. These cells are the primary location for the biotransformation of drugs.") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( "2020-10-12T11:03:51Z"^^xsd:dateTime) +AnnotationAssertion(Annotation( "PMID:29763190") "centrilobular hepatocyte") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "centrilobular region hepatocyte"@en) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (intestine goblet cell) + +AnnotationAssertion(Annotation( "PMID:1996606") Annotation( "PMID:24942678") "Goblet cells reside throughout the length of the small and large intestine and are responsible for the production and maintenance of the protective mucus blanket by synthesizing and secreting high-molecular-weight glycoproteins known as mucins. Human intestinal goblet cells secrete the MUC2 mucin, as well as a number of typical mucus components: CLCA1, FCGBP, AGR2, ZG16, and TFF3.") +AnnotationAssertion( ) +AnnotationAssertion( "2020-10-14T14:59:07Z"^^xsd:dateTime) +AnnotationAssertion(Annotation( "PMID:1996606") "intestinal goblet cell") +AnnotationAssertion(rdfs:label "intestine goblet cell"@en) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (intestinal tuft cell) + +AnnotationAssertion(Annotation( "PMID:22527717") "Any brush cell that is part of the intestinal epithelium.") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( "2020-10-15T12:47:46Z"^^xsd:dateTime) +AnnotationAssertion(Annotation( "PMID:22527717") "intestinal brush cell") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "intestinal tuft cell"@en) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (retrotrapezoid nucleus neuron) + +AnnotationAssertion(rdfs:label "retrotrapezoid nucleus neuron") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (mesonephric nephron tubule epithelial cell) + +AnnotationAssertion(rdfs:label "mesonephric nephron tubule epithelial cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (forebrain neuroblast) + +AnnotationAssertion(rdfs:label "forebrain neuroblast") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (lateral line nerve glial cell) + +AnnotationAssertion(rdfs:label "lateral line nerve glial cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (spinal cord radial glial cell) + +AnnotationAssertion(rdfs:label "spinal cord radial glial cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (pronephric nephron tubule epithelial cell) + +AnnotationAssertion(rdfs:label "pronephric nephron tubule epithelial cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (metanephric nephron tubule epithelial cell) + +AnnotationAssertion(rdfs:label "metanephric nephron tubule epithelial cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (lung goblet cell) @@ -23476,8 +40567,7 @@ EquivalentClasses( ObjectIntersection AnnotationAssertion(Annotation( "PMID:25311230") "A cell that is part of a cardiac valve.") AnnotationAssertion(Annotation( "PMID:30796046") "heart valve cell") AnnotationAssertion(rdfs:label "cardiac valve cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (growth plate cartilage chondrocyte) @@ -23497,25 +40587,39 @@ AnnotationAssertion(Annotation( "PMID:33355253") Annotation( ) "PNEC") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "lung neuroendocrine cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (posterior lateral line nerve glial cell) + +AnnotationAssertion(rdfs:label "posterior lateral line nerve glial cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (anterior lateral line nerve glial cell) + +AnnotationAssertion(rdfs:label "anterior lateral line nerve glial cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (posterior lateral line ganglion neuron) + +AnnotationAssertion(rdfs:label "posterior lateral line ganglion neuron") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (lung ciliated cell) AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "lung ciliated cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) SubClassOf( ) # Class: (lung secretory cell) AnnotationAssertion(rdfs:label "lung secretory cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) # Class: (trophectodermal cell) @@ -23641,8 +40745,6 @@ AnnotationAssertion(Annotation( "FMA:256165") AnnotationAssertion(rdfs:label "epithelial cell of urethra") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) # Class: (mesothelial cell of dura mater) @@ -23651,8 +40753,6 @@ AnnotationAssertion( "FMA:256516") "squamous mesothelial cell of dura mater") AnnotationAssertion(rdfs:label "mesothelial cell of dura mater") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) # Class: (fibroblast of papillary layer of dermis) @@ -23667,6 +40767,7 @@ SubClassOf(Annotation( AnnotationAssertion(Annotation( "GOC:tfm") "A fibroblast that is part of the areolar connective tissue.") AnnotationAssertion( "FMA:261279") AnnotationAssertion(rdfs:label "fibroblast of areolar connective tissue") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) SubClassOf( ObjectSomeValuesFrom( )) @@ -23675,8 +40776,28 @@ SubClassOf( ObjectSomeValuesFrom( "GOC:tfm") "A fibroblast that is part of the tunica adventitia of artery.") AnnotationAssertion( "FMA:261285") AnnotationAssertion(rdfs:label "fibroblast of tunica adventitia of artery") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) +# Class: (fibroblast of dense regular elastic tissue) + +AnnotationAssertion(Annotation( "GOC:tfm") "A fibroblast that is part of the dense regular elastic tissue.") +AnnotationAssertion( "FMA:261287") +AnnotationAssertion(rdfs:label "fibroblast of dense regular elastic tissue") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (fibrocyte of adventitia of ureter) + +AnnotationAssertion(Annotation( "GOC:tfm") "A fibrocyte that is part of the adventitia of ureter.") +AnnotationAssertion( ) +AnnotationAssertion( "FMA:261289") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "fibrocyte of adventitia of ureter") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) + # Class: (epicardial adipocyte) AnnotationAssertion(Annotation( "GOC:tfm") "A fat cell that is part of the epicardial fat.") @@ -23855,8 +40976,6 @@ AnnotationAssertion( ) AnnotationAssertion(rdfs:label "serous cell of epithelium of trachea") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) # Class: (serous cell of epithelium of bronchus) @@ -23866,7 +40985,6 @@ AnnotationAssertion( ) AnnotationAssertion(rdfs:label "serous cell of epithelium of bronchus") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) # Class: (serous cell of epithelium of terminal bronchiole) @@ -23874,7 +40992,6 @@ AnnotationAssertion(Annotation( "FMA:263082") AnnotationAssertion(rdfs:label "serous cell of epithelium of terminal bronchiole") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) # Class: (serous cell of epithelium of lobular bronchiole) @@ -23882,7 +40999,6 @@ AnnotationAssertion(Annotation( "FMA:263084") AnnotationAssertion(rdfs:label "serous cell of epithelium of lobular bronchiole") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) # Class: (transitional myocyte of interatrial septum) @@ -23938,6 +41054,7 @@ EquivalentClasses( ObjectIntersection AnnotationAssertion(Annotation( "GOC:tfm") "A type I vestibular sensory cell that is part of the epithelium of macula of utricle of membranous labyrinth.") AnnotationAssertion( "FMA:263188") AnnotationAssertion(rdfs:label "type 1 vestibular sensory cell of epithelium of macula of utricle of membranous labyrinth") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ObjectSomeValuesFrom( )) # Class: (type 1 vestibular sensory cell of epithelium of macula of saccule of membranous labyrinth) @@ -23945,13 +41062,29 @@ SubClassOf( ObjectSomeValuesFrom( "GOC:tfm") "A type I vestibular sensory cell that is part of the epithelium of macula of saccule of membranous labyrinth.") AnnotationAssertion( "FMA:263190") AnnotationAssertion(rdfs:label "type 1 vestibular sensory cell of epithelium of macula of saccule of membranous labyrinth") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (type 1 vestibular sensory cell of epithelium of crista of ampulla of semicircular duct of membranous labyrinth) + +AnnotationAssertion(Annotation( "GOC:tfm") "A type I vestibular sensory cell that is part of the epithelium of crista of ampulla of semicircular duct of membranous labyrinth.") +AnnotationAssertion( "FMA:263192") +AnnotationAssertion(rdfs:label "type 1 vestibular sensory cell of epithelium of crista of ampulla of semicircular duct of membranous labyrinth") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (type 2 vestibular sensory cell of stato-acoustic epithelium) + +AnnotationAssertion(Annotation( "GOC:tfm") "A type II vestibular sensory cell that is part of the stato-acoustic epithelium.") +AnnotationAssertion( "FMA:263194") +AnnotationAssertion(rdfs:label "type 2 vestibular sensory cell of stato-acoustic epithelium") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (type 2 vestibular sensory cell of epithelium of macula of utricle of membranous labyrinth) AnnotationAssertion(Annotation( "GOC:tfm") "A type II vestibular sensory cell that is part of the epithelium of macula of utricle of membranous labyrinth.") AnnotationAssertion( "FMA:263196") AnnotationAssertion(rdfs:label "type 2 vestibular sensory cell of epithelium of macula of utricle of membranous labyrinth") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ObjectSomeValuesFrom( )) # Class: (type 2 vestibular sensory cell of epithelium of macula of saccule of membranous labyrinth) @@ -23959,6 +41092,7 @@ SubClassOf( ObjectSomeValuesFrom( "GOC:tfm") "A type II vestibular sensory cell that is part of the epithelium of macula of saccule of membranous labyrinth.") AnnotationAssertion( "FMA:263198") AnnotationAssertion(rdfs:label "type 2 vestibular sensory cell of epithelium of macula of saccule of membranous labyrinth") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ObjectSomeValuesFrom( )) # Class: (type 2 vestibular sensory cell of epithelium of crista of ampulla of semicircular duct of membranous labyrinth) @@ -23977,7 +41111,6 @@ AnnotationAssertion(Annotation( "melanocyte of eyelid") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) -SubClassOf( ) # Class: (endothelial cell of venous sinus of red pulp of spleen) @@ -24009,8 +41142,6 @@ AnnotationAssertion(Annotation( "FMA:63602") "epithelial cell of vermiform appendix") AnnotationAssertion(rdfs:label "epithelial cell of appendix") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) # Class: (myocyte of sinoatrial node) @@ -24022,6 +41153,7 @@ AnnotationAssertion(Annotation( "sinoatrial node myocyte") AnnotationAssertion(Annotation( "FMA:67102") "sinuatrial node myocyte") AnnotationAssertion(rdfs:label "myocyte of sinoatrial node") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) # Class: (myocyte of atrioventricular node) @@ -24034,6 +41166,7 @@ AnnotationAssertion(Annotation( "GOC:pr") "atrioventricular node cell") AnnotationAssertion(Annotation( "FMA:67106") "atrioventricular node myocyte") AnnotationAssertion(rdfs:label "myocyte of atrioventricular node") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) # Class: (endothelial cell of Peyer's patch) @@ -24085,8 +41218,6 @@ AnnotationAssertion(Annotation( "FMA:67780") AnnotationAssertion(rdfs:label "epithelial cell of gallbladder") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) # Class: (myoepithelial cell of sweat gland) @@ -24139,6 +41270,7 @@ AnnotationAssertion(Annotation( "FMA:69794") AnnotationAssertion(Annotation( "GO:0061104") "adrenal chromaffin cell") AnnotationAssertion(rdfs:label "chromaffin cell of adrenal gland") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf(Annotation( "true") ) @@ -24149,6 +41281,7 @@ AnnotationAssertion( "chromaffin cell of adrenal cortex") AnnotationAssertion(rdfs:comment "Not clear this cell type exists. Can't call it a cortical adrenal cell because of different germ layer origin.") AnnotationAssertion(rdfs:label "adrenal cortex chromaffin cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) # Class: (stem cell of epidermis) @@ -24169,7 +41302,6 @@ AnnotationAssertion( "conjunctival epithelial cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) -SubClassOf( ) # Class: (epithelial cell of lacrimal canaliculus) @@ -24177,8 +41309,6 @@ AnnotationAssertion(Annotation( "FMA:70553") AnnotationAssertion(rdfs:label "epithelial cell of lacrimal canaliculus") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) # Class: (epithelial cell of external acoustic meatus) @@ -24186,8 +41316,6 @@ AnnotationAssertion(Annotation( "FMA:70555") AnnotationAssertion(rdfs:label "epithelial cell of external acoustic meatus") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) # Class: (epithelial cell of lacrimal duct) @@ -24203,8 +41331,6 @@ AnnotationAssertion(Annotation( "FMA:70560") AnnotationAssertion(rdfs:label "epithelial cell of lacrimal sac") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) # Class: (epithelial cell of nasolacrimal duct) @@ -24238,8 +41364,6 @@ AnnotationAssertion(Annotation( "FMA:70615") AnnotationAssertion(rdfs:label "mesothelial cell of anterior chamber of eye") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) # Class: (myoepithelial cell of dilator pupillae) @@ -24264,8 +41388,6 @@ AnnotationAssertion(Annotation( "FMA:70952") AnnotationAssertion(rdfs:label "epithelial cell of sweat gland") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) # Class: (epithelial cell of nephron) @@ -24273,8 +41395,6 @@ AnnotationAssertion(Annotation( "FMA:70965") AnnotationAssertion(rdfs:label "epithelial cell of nephron") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) # Class: (epithelial cell of glomerular capsule) @@ -24285,8 +41405,6 @@ AnnotationAssertion( "FMA:70966") "epithelial cell of Bowman's capsule") AnnotationAssertion(rdfs:label "epithelial cell of glomerular capsule") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) SubClassOf( ) SubClassOf(Annotation( "true") ) @@ -24308,8 +41426,6 @@ AnnotationAssertion(Annotation( "FMA:70980") AnnotationAssertion(rdfs:label "epithelial cell of intermediate tubule") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) # Class: (kidney collecting duct epithelial cell) @@ -24331,8 +41447,6 @@ AnnotationAssertion(Annotation( "FMA:72142") AnnotationAssertion(rdfs:label "mesothelial cell of parietal peritoneum") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) # Class: (mesothelial cell of visceral peritoneum) @@ -24342,8 +41456,6 @@ AnnotationAssertion( ) AnnotationAssertion(rdfs:label "mesothelial cell of visceral peritoneum") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) # Class: (melanocyte of skin) @@ -24356,7 +41468,6 @@ AnnotationAssertion( "melanocyte of skin") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) -SubClassOf( ) # Class: (chromaffin cell of ovary) @@ -24443,8 +41554,10 @@ SubClassOf(Annotation( # Class: (basal cell of urothelium) AnnotationAssertion(Annotation( "GOC:tfm") Annotation( "doi:10.1038/s41385-022-00565-0") "A basal cell that is part of the urothelium. Compared to other urothelial cell types, a basal cell of the urothelium is positioned along the basement membrane, is the most undifferentiated and serves a progenitor role.") +AnnotationAssertion( ) AnnotationAssertion( "FMA:84150") AnnotationAssertion(Annotation( "doi:10.1007/978-3-030-14366-4_8") Annotation( "doi:10.1111/cpr.13170") "urothelial basal cell") +AnnotationAssertion( ) AnnotationAssertion(Annotation( "doi:10.1038/s41385-022-00565-0") rdfs:comment "It has been noted in at least some mammalian species that the urothelial basal cell type is distinguished by expression of high levels of cytokeratin-5 (CK5), p63 and the signalling molecule Sonic hedgehog (Shh). Similar to intermediate cells, the urothelial basal cell type expresses CK17 but is negative for uroplakins (UPK) and CK20. Urothelial basal cells have also been noted to be smaller in diameter than urothelial intermediate cells.") AnnotationAssertion(rdfs:label "basal cell of urothelium") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) @@ -24459,6 +41572,7 @@ AnnotationAssertion( "FMA:84583") "smooth muscle fiber of prostate") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "smooth muscle cell of prostate") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) # Class: (cholangiocyte) @@ -24467,6 +41581,7 @@ AnnotationAssertion(Annotation( "FMA:86481") AnnotationAssertion( "epithelial cell of bile duct") AnnotationAssertion(rdfs:label "cholangiocyte") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( )))) @@ -24488,8 +41603,6 @@ AnnotationAssertion( "FMA:86736") "peritoneal mesothelial cell") AnnotationAssertion(rdfs:label "mesothelial cell of peritoneum") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) # Class: (mesothelial cell of pleura) @@ -24498,8 +41611,6 @@ AnnotationAssertion( "FMA:86737") "pleural mesothelial cell") AnnotationAssertion(rdfs:label "mesothelial cell of pleura") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) # Class: (mesothelial cell of parietal pleura) @@ -24507,16 +41618,15 @@ AnnotationAssertion(Annotation( "FMA:86738") AnnotationAssertion(rdfs:label "mesothelial cell of parietal pleura") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf(Annotation( "true") ) # Class: (mesothelial cell of visceral pleura) AnnotationAssertion(Annotation( "GOC:tfm") "A mesothelial cell that is part of the visceral pleura.") +AnnotationAssertion( ) AnnotationAssertion( "FMA:86739") +AnnotationAssertion( ) AnnotationAssertion(rdfs:label "mesothelial cell of visceral pleura") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) # Class: (nephron tubule epithelial cell) @@ -24544,42 +41654,35 @@ SubClassOf( ObjectSomeValuesFrom( "A cell that is part of a kidney.") AnnotationAssertion( "KUPO:0001010") AnnotationAssertion(rdfs:label "kidney cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (kidney interstitial cell) +AnnotationAssertion( "A cell that is part of kidney interstitium.") AnnotationAssertion( "KUPO:0001013") AnnotationAssertion(rdfs:label "kidney interstitial cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) # Class: (kidney medulla cell) +AnnotationAssertion( "A cell that is part of a renal medulla.") AnnotationAssertion( "KUPO:0001017") AnnotationAssertion(rdfs:label "kidney medulla cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) # Class: (kidney pelvis cell) +AnnotationAssertion( "A cell that is part of a renal pelvis.") AnnotationAssertion( "KUPO:0001018") AnnotationAssertion(rdfs:label "kidney pelvis cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) # Class: (kidney tubule cell) +AnnotationAssertion( "A cell that is part of a nephron tubule.") AnnotationAssertion( "KUPO:0001020") AnnotationAssertion(rdfs:label "kidney tubule cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) # Class: (kidney glomerular epithelial cell) @@ -24591,36 +41694,33 @@ SubClassOf( ObjectSomeValuesFrom( (kidney medulla collecting duct epithelial cell) +AnnotationAssertion( "An epithelial cell that is part of a renal medulla collecting duct.") AnnotationAssertion( "KUPO:0001060") AnnotationAssertion(rdfs:label "kidney medulla collecting duct epithelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (kidney inner medulla collecting duct epithelial cell) AnnotationAssertion( "An epithelial cell that is part of some inner medullary collecting duct.") AnnotationAssertion( "KUPO:0001061") AnnotationAssertion(rdfs:label "kidney inner medulla collecting duct epithelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) # Class: (kidney outer medulla collecting duct epithelial cell) +AnnotationAssertion( "An epithelial cell that is part of an outer medullary collecting duct.") AnnotationAssertion( "KUPO:0001062") AnnotationAssertion(rdfs:label "kidney outer medulla collecting duct epithelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) # Class: (kidney cortex collecting duct epithelial cell) +AnnotationAssertion( "An epithelial cell that is part of a cortical collecting duct.") AnnotationAssertion( "KUPO:0001063") AnnotationAssertion(rdfs:label "kidney cortex collecting duct epithelial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) -SubClassOf( ObjectSomeValuesFrom( )) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (kidney papillary duct principal epithelial cell) @@ -24653,16 +41753,14 @@ SubClassOf( ObjectSomeValuesFrom( "KUPO:0001115") AnnotationAssertion(rdfs:label "lower urinary tract cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ObjectSomeValuesFrom( )) # Class: (ureteral cell) AnnotationAssertion( "KUPO:0001116") AnnotationAssertion(rdfs:label "ureteral cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ObjectSomeValuesFrom( )) # Class: (kidney nerve cell) @@ -24711,9 +41809,28 @@ SubClassOf( ObjectSomeValuesFrom( "KUPO:0001028") AnnotationAssertion(Annotation( "GO:0072052") "juxtaglomerulus cell") AnnotationAssertion(rdfs:label "juxtaglomerular complex cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (kidney cortex interstitial cell) + +AnnotationAssertion( "KUPO:0001091") +AnnotationAssertion(rdfs:label "kidney cortex interstitial cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf(Annotation( "true") ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (kidney medulla interstitial cell) + +AnnotationAssertion( "KUPO:0001092") +AnnotationAssertion(rdfs:label "kidney medulla interstitial cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "true") ) +SubClassOf(Annotation( "true") ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (kidney interstitial fibroblast) AnnotationAssertion( ) @@ -24928,7 +42045,9 @@ SubClassOf( ObjectSomeValuesFrom( (ureter smooth muscle cell) +AnnotationAssertion( ) AnnotationAssertion( "KUPO:0001118") +AnnotationAssertion( ) AnnotationAssertion(rdfs:label "ureter smooth muscle cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "true") ) @@ -25314,11 +42433,11 @@ SubClassOf( (kidney collecting duct cell) +AnnotationAssertion( "A cell that is part of a collecting duct of renal tubule.") AnnotationAssertion( "KUPO:0001012") AnnotationAssertion( "Wikipedia:Kidney_collecting_duct_cell") AnnotationAssertion(rdfs:label "kidney collecting duct cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) # Class: (vasa recta descending limb cell) @@ -25366,16 +42485,14 @@ AnnotationAssertion( "KUPO:0001120") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "bladder cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ObjectSomeValuesFrom( )) # Class: (urethra cell) AnnotationAssertion( "KUPO:0001123") AnnotationAssertion(rdfs:label "urethra cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf(Annotation( "true") ) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ObjectSomeValuesFrom( )) # Class: (bladder urothelial cell) @@ -25424,9 +42541,19 @@ EquivalentClasses( ObjectIntersection AnnotationAssertion(Annotation( "PMID:18603310") "A neuron residing in the olfactory bulb that serve to process and refine signals arising from olfactory sensory neurons") AnnotationAssertion(rdfs:label "olfactory bulb interneuron") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (sensory neuron of dorsal root ganglion) + +AnnotationAssertion(Annotation( "MP:0004297") "A sensory neuron of the dorsal root ganglia that senses body position and sends information about how much the muscle is stretched to the spinal cord.") +AnnotationAssertion(Annotation( "MP:0004297") "proprioceptive neuron") +AnnotationAssertion(rdfs:label "sensory neuron of dorsal root ganglion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (mitral cell) AnnotationAssertion(Annotation( "MP:0009954") "The large glutaminergic nerve cells whose dendrites synapse with axons of the olfactory receptor neurons in the glomerular layer of the olfactory bulb, and whose axons pass centrally in the olfactory tract to the olfactory cortex.") @@ -25465,18 +42592,18 @@ EquivalentClasses( ObjectIntersection # Class: (lung endothelial cell) -AnnotationAssertion( ) AnnotationAssertion( "endothelial cell of lung") AnnotationAssertion( "pulmonary vessel endothelial cell") -AnnotationAssertion( ) AnnotationAssertion(rdfs:label "lung endothelial cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ObjectSomeValuesFrom( )) # Class: (pulmonary artery endothelial cell) +AnnotationAssertion( ) AnnotationAssertion( "BTO:0001141") AnnotationAssertion(Annotation( "BTO:0001141") "PAEC cell") +AnnotationAssertion( ) AnnotationAssertion(rdfs:label "pulmonary artery endothelial cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ObjectSomeValuesFrom( )) @@ -25503,7 +42630,7 @@ SubClassOf( ObjectSomeValuesFrom( "NPX:PDR") Annotation( "https://orcid.org/0000-0001-5208-3432") "A vascular endothelial cell found in colon blood vessels.") AnnotationAssertion( "CALOHA:TS-2397") -AnnotationAssertion(Annotation( "CALOHA:TS-2397") Annotation( ) "colon endothelial cells") +AnnotationAssertion(Annotation( "CALOHA:TS-2397") Annotation( ) "colon endothelial cells") AnnotationAssertion(Annotation( "CALOHA:TS-2397") "colonic endothelial cell") AnnotationAssertion(rdfs:label "colon endothelial cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) @@ -25791,7 +42918,9 @@ EquivalentClasses( ObjectIntersection # Class: (articular chondrocyte) AnnotationAssertion(Annotation( "NPX:PDR") "Chondrocyte forming the hyaline cartilage found in joints.") +AnnotationAssertion( ) AnnotationAssertion( "CALOHA:TS-0056") +AnnotationAssertion( ) AnnotationAssertion(rdfs:label "articular chondrocyte") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) @@ -25838,7 +42967,6 @@ AnnotationAssertion( "These cells are found primarily, but not exclusively, in primates including humans") AnnotationAssertion(rdfs:label "epidermal melanocyte") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) # Class: (peripheral blood mononuclear cell) @@ -25871,8 +42999,7 @@ AnnotationAssertion( "2014-03-26T22:14:56Z") AnnotationAssertion( "CL:2000004") AnnotationAssertion(rdfs:label "pituitary gland cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (brain macroglial cell) @@ -26009,7 +43136,7 @@ AnnotationAssertion( "2014-06-24T23:16:53Z") AnnotationAssertion( "CL:2000020") AnnotationAssertion(rdfs:label "inner cell mass cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (sebaceous gland cell) @@ -26018,8 +43145,7 @@ AnnotationAssertion( "2014-06-24T23:17:00Z") AnnotationAssertion( "CL:2000021") AnnotationAssertion(rdfs:label "sebaceous gland cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (cardiac septum cell) @@ -26028,8 +43154,7 @@ AnnotationAssertion( "2014-06-24T23:17:07Z") AnnotationAssertion( "CL:2000022") AnnotationAssertion(rdfs:label "cardiac septum cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (spinal cord ventral column interneuron) @@ -26092,8 +43217,7 @@ AnnotationAssertion( "2014-06-25T01:17:50Z") AnnotationAssertion( "CL:2000030") AnnotationAssertion(rdfs:label "hypothalamus cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (lateral line ganglion neuron) @@ -26198,7 +43322,6 @@ AnnotationAssertion( AnnotationAssertion( "CL:2000045") AnnotationAssertion(rdfs:label "foreskin melanocyte") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) # Class: (ventricular cardiac muscle cell) @@ -26293,11 +43416,9 @@ EquivalentClasses( ObjectIntersection # Class: (prostate gland microvascular endothelial cell) AnnotationAssertion(Annotation( "GOC:TermGenie") "Any microvascular endothelial cell that is part of a prostate gland.") -AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( "2014-10-07T17:46:27Z") AnnotationAssertion( "CL:2000059") -AnnotationAssertion( ) AnnotationAssertion(rdfs:comment "http://www.sciencellonline.com/site/productInformation.php?keyword=4400") AnnotationAssertion(rdfs:label "prostate gland microvascular endothelial cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) @@ -26320,9 +43441,11 @@ EquivalentClasses( ObjectIntersection # Class: (placental amniotic mesenchymal stromal cell) AnnotationAssertion(Annotation( "GOC:TermGenie") "Any mesenchymal stem cell that is part of a placenta.") +AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( "2014-10-07T17:51:11Z") AnnotationAssertion( "CL:2000061") +AnnotationAssertion( ) AnnotationAssertion(rdfs:comment "http://www.sciencellonline.com/site/productInformation.php?keyword=7140") AnnotationAssertion(rdfs:label "placental amniotic mesenchymal stromal cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) @@ -26330,11 +43453,9 @@ EquivalentClasses( ObjectIntersection # Class: (placental villus capillary endothelial cell) AnnotationAssertion(Annotation( "GOC:TermGenie") "Any capillary endothelial cell that is part of a placenta.") -AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( "2014-10-07T17:55:56Z") AnnotationAssertion( "CL:2000062") -AnnotationAssertion( ) AnnotationAssertion(rdfs:comment "http://www.ncbi.nlm.nih.gov/books/NBK53245/") AnnotationAssertion(rdfs:label "placental villus capillary endothelial cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) @@ -26526,7 +43647,6 @@ AnnotationAssertion( AnnotationAssertion( "CL:2000081") AnnotationAssertion(rdfs:label "melanocyte of skin of face") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) # Class: (melanocyte of foreskin) @@ -26536,7 +43656,6 @@ AnnotationAssertion( AnnotationAssertion( "CL:2000082") AnnotationAssertion(rdfs:label "melanocyte of foreskin") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) # Class: (hair follicle dermal papilla cell of scalp) @@ -26817,7 +43936,7 @@ AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "brain vascular cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (mammillary body neuron) @@ -26919,7 +44038,6 @@ AnnotationAssertion( "PMID:31819095") Annotation( "PMID:34082079") rdfs:comment "Cellular functions and extracellular interactions of choroidal melanocytes are distinct to skin melanocytes. They might have both neuroectodermal as well as mesectodermal origins.") AnnotationAssertion(rdfs:label "choroidal melanocyte") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) # Class: (stromal cell of thymus) @@ -26984,6 +44102,7 @@ AnnotationAssertion( ) AnnotationAssertion(rdfs:label "kidney connecting tubule principal cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) # Class: (renal medullary fibroblast) @@ -27031,16 +44150,18 @@ AnnotationAssertion(Annotation( ) AnnotationAssertion( "2022-11-30T14:35:08Z"^^xsd:dateTime) AnnotationAssertion(rdfs:label "interstitial cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (valve interstitial cell) AnnotationAssertion(Annotation( ) Annotation( "PMID:25311230") Annotation( "https://doi.org/10.1098/rsif.2017.0580") Annotation( "https://doi.org/10.1161/ATVBAHA.120.314789") Annotation( "https://doi.org/10.1161/JAHA.117.006339") Annotation( "https://doi.org/10.2353/ajpath.2007.070251") "An interstitial cell that is part of a cardiac valve leaflet. Along with valve endothelial cells, a valve interstitial cell maintains tissue homeostasis for the function of cardiac valves through secreting biochemical signals, matrix proteins and matrix remodeling enzymes.") +AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( "2022-12-06T14:18:45Z"^^xsd:dateTime) -AnnotationAssertion(Annotation( "PMID:25311230") Annotation( "PMID:30796046") Annotation( ) "VIC") +AnnotationAssertion(Annotation( "PMID:25311230") Annotation( "PMID:30796046") Annotation( ) "VIC") AnnotationAssertion( "cardiac valve interstitial cell") AnnotationAssertion(Annotation( "PMID:25311230") "valvular interstitial cell") +AnnotationAssertion( ) AnnotationAssertion(Annotation( "PMID:25311230") rdfs:comment "Activated valve interstitial cells undergo continual turn over into deactivated fibroblasts and other cell fates (such as apoptosis).") AnnotationAssertion(rdfs:label "valve interstitial cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) @@ -27051,7 +44172,7 @@ SubClassOf( ObjectSomeValuesFrom( "PMID:25311230") "An endothelial cell that lines a surface of a cardiac valve leaflet. Along with valve interstitial cells, a valve endothelial cell maintains tissue homeostasis for the function of cardiac valves through secreting biochemical signals, matrix proteins and matrix remodeling enzymes.") AnnotationAssertion( ) AnnotationAssertion( "2022-12-09T11:58:49Z"^^xsd:dateTime) -AnnotationAssertion(Annotation( "PMID:25311230") Annotation( "PMID:30796046") Annotation( ) "VEC") +AnnotationAssertion(Annotation( "PMID:25311230") Annotation( "PMID:30796046") Annotation( ) "VEC") AnnotationAssertion(Annotation( "PMID:25311230") "valvular endothelial cell") AnnotationAssertion(Annotation( "PMID:25311230") rdfs:comment "At least in some mammalian species, a valve endothelial cell expresses CD31. Valve endothelial cells can undergo an endothelial to mesenchymal transition to acquire a fibroblast or myofibroblast phenotype that leads to changes in the microenvironmental signals and facilitates tissue regeneration.") AnnotationAssertion(rdfs:label "valve endothelial cell") @@ -27063,13 +44184,14 @@ AnnotationAssertion(Annotation( "2023-01-25T11:06:01Z"^^xsd:dateTime) AnnotationAssertion( "ciliated cell of the respiratory tract") AnnotationAssertion(rdfs:label "respiratory ciliated cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ObjectSomeValuesFrom( )) # Class: (dental pulp stem cell) AnnotationAssertion(Annotation( ) Annotation( "DOI:10.1177/154405910208100806") "A dental pulp cell that possesses stem-cell-like qualities, including self-renewal capability and multi-lineage differentiation.") AnnotationAssertion( "2023-01-10T14:02:02Z"^^xsd:dateTime) -AnnotationAssertion(Annotation( ) "DPSC") +AnnotationAssertion(Annotation( ) "DPSC") AnnotationAssertion(rdfs:label "dental pulp stem cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) @@ -27086,6 +44208,16 @@ AnnotationAssertion(Annotation( "endometrial ciliated epithelial cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +# Class: (ureteric bud cell) + +AnnotationAssertion(Annotation( "PMID:17133361") Annotation( "PMID:24183650") Annotation( "PMID:9374839") "An epithelial cell that is part of a ureteric bud. A ureteric bud cell has the potential to induce metanephric mesenchymal cells to proliferate and convert to epithelia that form renal tubules via: (1) the secretion of multiple diffusible growth factors that rescue renal progenitors from apoptosis and stimulate them to proliferate and (2) contact-dependent mechanisms that induce mesenchymal-epithelial conversion.") +AnnotationAssertion( "https://orcid.org/0000-0002-1425-877X") +AnnotationAssertion( "2023-10-13T11:22:42Z"^^xsd:dateTime) +AnnotationAssertion(Annotation( "PMID:24183650") Annotation( ) "UB cell") +AnnotationAssertion(rdfs:label "ureteric bud cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "PMID:9374839") ObjectSomeValuesFrom( )) + # Class: (endothelial cell of venule of lymph node) AnnotationAssertion(Annotation( "PMID:28217126") "A(n) endothelial cell that is part of a(n) venule of lymph node.") @@ -27126,7 +44258,9 @@ EquivalentClasses( ObjectIntersection # Class: (serous secreting cell of bronchus submucosal gland) AnnotationAssertion(Annotation( "PMID:5487122") Annotation( "PMID:9651178") "A(n) serous secreting cell that is part of a(n) bronchus submucosal gland.") +AnnotationAssertion( ) AnnotationAssertion( ) +AnnotationAssertion( ) AnnotationAssertion(rdfs:label "serous secreting cell of bronchus submucosal gland") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) @@ -27200,7 +44334,7 @@ EquivalentClasses( ObjectIntersection AnnotationAssertion(Annotation( "PMID:25236977") Annotation( "PMID:33796062") "A star-shaped glial cell that is part of some retina. This cell links neurons to blood vessels and may provide structural and physiological support to optic nerve head axons.") AnnotationAssertion( ) AnnotationAssertion( "2023-03-02T14:38:32Z"^^xsd:dateTime) -AnnotationAssertion(Annotation( ) Annotation( "PMID:33796062") "retinal astroglia") +AnnotationAssertion(Annotation( "PMID:33796062") Annotation( ) "retinal astroglia") AnnotationAssertion( ) AnnotationAssertion(Annotation( "PMID:32555229") Annotation( "PMID:33796062") rdfs:comment "In response to elevated intraocular pressure, a retinal astrocyte may modulate extracellular matrix remodeling. In the human retina, a retinal astrocyte is GFAP-positive, SOD3-positive and GYPC-positive.") AnnotationAssertion(rdfs:label "retinal astrocyte") @@ -27215,6 +44349,7 @@ AnnotationAssertion( "2023-03-16T09:38:17Z"^^xsd:dateTime) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "bronchiolar smooth muscle cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ObjectSomeValuesFrom( )) # Class: (lung megakaryocyte) @@ -27226,8 +44361,8 @@ AnnotationAssertion( "2023-03-16T11:31:23Z"^^xsd:dateTime) AnnotationAssertion(Annotation( "PMID:36524131") "lung resident megakaryocyte") AnnotationAssertion(Annotation( "PMID:36524131") "lung-resident megakaryocyte") -AnnotationAssertion(Annotation( "PMID:36524131") Annotation( ) "MKL") -AnnotationAssertion(Annotation( "PMID:33351116") Annotation( ) Annotation( ) "lung MKs") +AnnotationAssertion(Annotation( "PMID:36524131") Annotation( ) "MKL") +AnnotationAssertion(Annotation( "PMID:33351116") Annotation( ) Annotation( ) "lung MKs") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "lung megakaryocyte") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) @@ -27282,10 +44417,12 @@ EquivalentClasses( ObjectIntersection # Class: (lung perichondrial fibroblast) AnnotationAssertion(Annotation( "PMID:36543915") "A perichondrial fibroblast that is part of the lung.") +AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion( "2023-03-16T16:15:39Z"^^xsd:dateTime) -AnnotationAssertion(Annotation( "PMID:36543915") Annotation( ) "PC-fibro") +AnnotationAssertion(Annotation( "PMID:36543915") Annotation( ) "PC-fibro") +AnnotationAssertion( ) AnnotationAssertion(rdfs:label "lung perichondrial fibroblast") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) @@ -27314,6 +44451,7 @@ AnnotationAssertion( "2023-05-18T12:07:45Z"^^xsd:dateTime) AnnotationAssertion(Annotation( "PMID:10191060") Annotation( "PMID:12128258") Annotation( "PMID:34880760") Annotation( "https://orcid.org/0000-0002-2244-7917") rdfs:comment "Frequently used when describing the developing nervous system in zebrafish. A catecholaminergic neuron expresses tyrosine hydroxylase (TH), tyrosine hydroxylase 2 (TH2), aromatic amino acid decarboxylase (AADC), dopamine b-hydroxylase (DBH), and phenylethanolamine-N-methyl transferase (PEMT), which are enzymes necessary for catecholamine synthesis.") AnnotationAssertion(rdfs:label "catecholaminergic neuron") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (perivascular cell) @@ -27321,7 +44459,39 @@ AnnotationAssertion(Annotation( ) AnnotationAssertion( "2023-08-22T13:40:28Z"^^xsd:dateTime) AnnotationAssertion(rdfs:label "perivascular cell") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (airway submucosal gland duct ciliated cell) + +AnnotationAssertion(Annotation( "PMID:17707699") Annotation( "PMID:30864819") "A ciliated cell that is part of a ciliated duct of an airway submucosal gland.") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( "2023-09-08T10:32:27Z"^^xsd:dateTime) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "airway submucosal gland duct ciliated cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (luminal adaptive secretory precursor cell of mammary gland) + +AnnotationAssertion(Annotation( "PMID:19648928") Annotation( "PMID:35617956") Annotation( "https://nrs.harvard.edu/URN-3:HUL.INSTREPOS:37368328") Annotation( "https://orcid.org/0000-0001-6677-8489") "A luminal epithelial cell of the mammary gland that can proliferate and has the potential to differentiate into a lactocyte during pregnancy. In humans, a luminal adaptive secretory precursor cell can be identified by high levels of the markers EpCAM and CD49f, and in mice it can be identified by low levels of CD29 and high levels of CD14, Kit, CD61, and Tspan8.") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( "2023-10-13T13:02:55Z"^^xsd:dateTime) +AnnotationAssertion(Annotation( "PMID:35617956") "alveolar cell") +AnnotationAssertion(Annotation( "PMID:26390871") "alveolar progenitor") +AnnotationAssertion(Annotation( "doi:10.1101/2023.04.21.537845") "luminal progenitor") +AnnotationAssertion(Annotation( "PMID:20346151") "luminal progenitor cell") +AnnotationAssertion(Annotation( "PMID:37380767") "luminal secretory cell") +AnnotationAssertion(Annotation( "https://nrs.harvard.edu/URN-3:HUL.INSTREPOS:37368328") "ER-negative luminal alveolar progenitor") +AnnotationAssertion(Annotation( "https://nrs.harvard.edu/URN-3:HUL.INSTREPOS:37368328") Annotation( ) "AP") +AnnotationAssertion(Annotation( "PMID:35617956") Annotation( ) "AV") +AnnotationAssertion(Annotation( "https://orcid.org/0000-0001-6677-8489") Annotation( ) "LASP") +AnnotationAssertion(Annotation( "doi:10.1101/2023.04.21.537845") Annotation( ) "LP") +AnnotationAssertion(Annotation( "PMID:37380767") Annotation( ) "LumSec") +AnnotationAssertion(rdfs:label "luminal adaptive secretory precursor cell of mammary gland") +SubClassOf( ) +SubClassOf( ) # Class: (enteroglial cell) @@ -27329,7 +44499,7 @@ AnnotationAssertion(Annotation( ) AnnotationAssertion( "2023-04-03T15:15:40Z"^^xsd:dateTime) AnnotationAssertion(Annotation( "PMID:11169131") Annotation( "PMID:25170211") "enteric glial cell") -AnnotationAssertion(Annotation( ) Annotation( "PMID:11169131") "enteric glia") +AnnotationAssertion(Annotation( "PMID:11169131") Annotation( ) "enteric glia") AnnotationAssertion(rdfs:label "enteroglial cell") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ObjectSomeValuesFrom( )) @@ -27375,6 +44545,108 @@ AnnotationAssertion(rdfs:label "repr SubClassOf( ) DisjointClasses( ) +# Class: (vacuole inheritance) + +AnnotationAssertion(Annotation( "GOC:mcc") Annotation( "PMID:10873824") Annotation( "PMID:14616069") "The distribution of vacuoles into daughter cells after mitosis or meiosis, mediated by interactions between vacuoles and the cytoskeleton.") +AnnotationAssertion( ) +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0000011") +AnnotationAssertion(rdfs:label "vacuole inheritance") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses( ObjectSomeValuesFrom( )) + +# Class: (regulation of DNA recombination) + +AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198506732") "Any process that modulates the frequency, rate or extent of DNA recombination, a DNA metabolic process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0000018") +AnnotationAssertion(rdfs:label "regulation of DNA recombination") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (acyl binding) + +AnnotationAssertion(Annotation( "GOC:curators") Annotation( "ISBN:0198506732") "Binding to an acyl group, any group formally derived by removal of the hydroxyl group from the acid function of a carboxylic acid.") +AnnotationAssertion( "acyl-CoA or acyl binding") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0000035") +AnnotationAssertion(rdfs:label "acyl binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (transition metal ion transport) + +AnnotationAssertion(Annotation( "ISBN:0198506732") "The directed movement of transition metal ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver.") +AnnotationAssertion( "transition metal transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0000041") +AnnotationAssertion(rdfs:label "transition metal ion transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (mitotic sister chromatid segregation) + +AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:jl") "The cell cycle process in which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the mitotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner. One homolog of each morphologic type goes into each of the resulting chromosome sets.") +AnnotationAssertion( "GO:0016359") +AnnotationAssertion( "mitotic chromosome segregation") +AnnotationAssertion( "mitotic sister-chromatid adhesion release") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0000070") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "mitotic sister chromatid segregation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (Golgi membrane) + +AnnotationAssertion(Annotation( "GOC:mah") "The lipid bilayer surrounding any of the compartments of the Golgi apparatus.") +AnnotationAssertion( "Golgi apparatus membrane") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0000139") +AnnotationAssertion(rdfs:label "Golgi membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (nucleotide binding) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "ISBN:0198547684") "Binding to a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose.") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0000166") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "nucleotide binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (microtubule cytoskeleton organization) + +AnnotationAssertion(Annotation( "GOC:mah") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/23114"^^xsd:anyURI) +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/23195"^^xsd:anyURI) +AnnotationAssertion(Annotation( "GOC:mah") "microtubule cytoskeleton organisation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:mah") "microtubule cytoskeleton organization and biogenesis") +AnnotationAssertion( "GO:0000226") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "microtubule cytoskeleton organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (nuclear chromosome) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mah") "A chromosome that encodes the nuclear genome and is found in the nucleus of a eukaryotic cell during the cell cycle phases when the nucleus is intact.") +AnnotationAssertion( "nuclear interphase chromosome") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0000228") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "nuclear chromosome") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (polysaccharide biosynthetic process) AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways resulting in the formation of a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically.") @@ -27387,6 +44659,211 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0000271") AnnotationAssertion(rdfs:label "polysaccharide biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (polysaccharide catabolic process) + +AnnotationAssertion(Annotation( "PMID:33139480") "The chemical reactions and pathways resulting in the breakdown of a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically.") +AnnotationAssertion( "GO:0044244") +AnnotationAssertion( "polysaccharide breakdown") +AnnotationAssertion( "polysaccharide catabolism") +AnnotationAssertion( "polysaccharide degradation") +AnnotationAssertion( "multicellular organismal polysaccharide catabolic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0000272") +AnnotationAssertion(rdfs:label "polysaccharide catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (mitotic cell cycle) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "ISBN:0815316194") Annotation( "Reactome:69278") "Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent.") +AnnotationAssertion( "GO:0007067") +AnnotationAssertion( "Wikipedia:Mitosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "mitosis") +AnnotationAssertion( "GO:0000278") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:comment "Note that this term should not be confused with 'GO:0140014 ; mitotic nuclear division'. 'GO:0000278 ; mitotic cell cycle represents the entire mitotic cell cycle, while 'GO:0140014 ; mitotic nuclear division' specifically represents the actual nuclear division step of the mitotic cell cycle.") +AnnotationAssertion(rdfs:label "mitotic cell cycle") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectAllValuesFrom( )) + +# Class: (nuclear division) + +AnnotationAssertion(Annotation( "GOC:mah") "The division of a cell nucleus into two nuclei, with DNA and other nuclear contents distributed between the daughter nuclei.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "karyokinesis") +AnnotationAssertion( "GO:0000280") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "nuclear division") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (adenine nucleotide transmembrane transporter activity) + +AnnotationAssertion(Annotation( "PMID:11566870") "Enables the transfer of adenine nucleotides (AMP, ADP, and ATP) from one side of a membrane to the other.") +AnnotationAssertion(Annotation(rdfs:label "PMP34-mediated exchange of cytosolic ATP for peroxisomal AMP") "Reactome:R-HSA-389652") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0000295") +AnnotationAssertion(rdfs:label "adenine nucleotide transmembrane transporter activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (organellar ribosome) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:mcc") "A ribosome contained within a subcellular membrane-bounded organelle.") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0000313") +AnnotationAssertion(rdfs:label "organellar ribosome") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (lytic vacuole) + +AnnotationAssertion(Annotation( "GOC:krc") "A vacuole that is maintained at an acidic pH and which contains degradative enzymes, including a wide variety of acid hydrolases.") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0000323") +AnnotationAssertion(rdfs:label "lytic vacuole") +SubClassOf( ) + +# Class: (embryonic axis specification) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:go_curators") Annotation( "GOC:sdb_2009") Annotation( "GOC:tb") "The establishment, maintenance and elaboration of a pattern along a line or a point in an embryo.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "embryonic axis determination") +AnnotationAssertion( "GO:0000578") +AnnotationAssertion(rdfs:label "embryonic axis specification") +SubClassOf( ) +SubClassOf( ) + +# Class: (nuclear membrane fusion) + +AnnotationAssertion(Annotation( "GOC:elh") "The joining of 2 or more lipid bilayer membranes that surround the nucleus.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0000740") +AnnotationAssertion(rdfs:label "nuclear membrane fusion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (karyogamy) + +AnnotationAssertion(Annotation( "GOC:elh") "The creation of a single nucleus from multiple nuclei as a result of fusing the lipid bilayers that surround each nuclei.") +AnnotationAssertion( "GO:0007335") +AnnotationAssertion( "Wikipedia:Karyogamy") +AnnotationAssertion( "nuclear fusion") +AnnotationAssertion( "nuclear fusion during karyogamy") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0000741") +AnnotationAssertion(rdfs:label "karyogamy") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (syncytium formation by plasma membrane fusion) + +AnnotationAssertion(Annotation( "GOC:mtg_muscle") Annotation( "GOC:tb") "The formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells.") +AnnotationAssertion( "cell fusion") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0000768") +AnnotationAssertion(rdfs:label "syncytium formation by plasma membrane fusion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (chromatin) + +AnnotationAssertion(Annotation( "GOC:elh") Annotation( "PMID:20404130") "The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome.") +AnnotationAssertion( "GO:0000789") +AnnotationAssertion( "GO:0000790") +AnnotationAssertion( "GO:0005717") +AnnotationAssertion( "NIF_Subcellular:sao1615953555") +AnnotationAssertion( "cytoplasmic chromatin") +AnnotationAssertion( "nuclear chromatin") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "chromosome scaffold") +AnnotationAssertion( "GO:0000785") +AnnotationAssertion(rdfs:comment "Chromosomes include parts that are not part of the chromatin. Examples include the kinetochore.") +AnnotationAssertion(rdfs:label "chromatin") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (euchromatin) + +AnnotationAssertion(Annotation( "PMID:32017156") "A dispersed and relatively uncompacted form of chromatin that is in a transcription-competent conformation.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/22355"^^xsd:anyURI) +AnnotationAssertion( "GO:0005719") +AnnotationAssertion( "GO:0035327") +AnnotationAssertion( "NIF_Subcellular:sao445485807") +AnnotationAssertion( "Wikipedia:Euchromatin") +AnnotationAssertion( "transcriptionally active chromatin") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "nuclear euchromatin") +AnnotationAssertion( "GO:0000791") +AnnotationAssertion(rdfs:label "euchromatin") +SubClassOf( ) + +# Class: (heterochromatin) + +AnnotationAssertion(Annotation( "PMID:32017156") "A compact and highly condensed form of chromatin that is refractory to transcription.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/22355"^^xsd:anyURI) +AnnotationAssertion( "GO:0005720") +AnnotationAssertion( "GO:0035328") +AnnotationAssertion( "NIF_Subcellular:sao581845896") +AnnotationAssertion( "Wikipedia:Heterochromatin") +AnnotationAssertion( "transcriptionally inactive chromatin") +AnnotationAssertion( "transcriptionally silent chromatin") +AnnotationAssertion( "nuclear heterochromatin") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0000792") +AnnotationAssertion(rdfs:label "heterochromatin") +SubClassOf( ) + +# Class: (sister chromatid segregation) + +AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:elh") "The cell cycle process in which sister chromatids are organized and then physically separated and apportioned to two or more sets.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0000819") +AnnotationAssertion(rdfs:label "sister chromatid segregation") +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of glutamine family amino acid metabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline.") +AnnotationAssertion( "regulation of glutamine family amino acid metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0000820") +AnnotationAssertion(rdfs:label "regulation of glutamine family amino acid metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (cell morphogenesis) + +AnnotationAssertion(Annotation( "GOC:clt") Annotation( "GOC:dph") Annotation( "GOC:go_curators") Annotation( "GOC:tb") "The developmental process in which the size or shape of a cell is generated and organized.") +AnnotationAssertion( "GO:0007148") +AnnotationAssertion( "GO:0045790") +AnnotationAssertion( "GO:0045791") +AnnotationAssertion( "cellular morphogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0000902") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "cell morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (response to acid chemical) + +AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "GOC:rn") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by the chemical structure of the anion portion of a dissociated acid (rather than the acid acting as a proton donor). The acid chemical may be in gaseous, liquid or solid form.") +AnnotationAssertion( "response to acid") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "response to acid anion") +AnnotationAssertion( "response to oxoanion") +AnnotationAssertion( "GO:0001101") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:comment "This term should be used to describe a response to a specific acid as a chemical. E.g., if an organism were responding to glutamate, then the response would be glutamate-specific; the organism is actually responding to the chemical structure of the anion portion of the dissociated acid. Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. If annotating experiments where an acid is playing a role as a proton donor, please annotate to GO:0010447 'response to acidic pH' instead.") +AnnotationAssertion(rdfs:label "response to acid chemical") +SubClassOf( ) # Class: (skeletal system development) @@ -27395,6 +44872,7 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0001501") AnnotationAssertion(rdfs:label "skeletal system development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) # Class: (ossification) @@ -27408,6 +44886,7 @@ AnnotationAssertion( "GO:0001503") AnnotationAssertion(rdfs:comment "Note that this term does not have a 'developmental process' parent because ossification isn't necessarily developmental, can also occur as part of bone remodeling. Instead use 'ossification involved in bone maturation ; GO:0043931'.") AnnotationAssertion(rdfs:label "ossification") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) # Class: (neurotransmitter uptake) @@ -27421,18 +44900,8 @@ AnnotationAssertion( "GO:0001504") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "neurotransmitter uptake") -SubClassOf( ) SubClassOf( ) -# Class: (regulation of neurotransmitter levels) - -AnnotationAssertion(Annotation( "GOC:jl") "Any process that modulates levels of neurotransmitter.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0001505") -AnnotationAssertion(rdfs:label "regulation of neurotransmitter levels") -SubClassOf( ObjectSomeValuesFrom( )) -SubClassOf( ObjectAllValuesFrom( )) - # Class: (action potential) AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:go_curators") Annotation( "GOC:tb") Annotation( "ISBN:978-0-07-139011-8") "A process in which membrane potential cycles through a depolarizing spike, triggered in response to depolarization above some threshold, followed by repolarization. This cycle is driven by the flow of ions through various voltage gated channels with different thresholds and ion specificities.") @@ -27446,6 +44915,86 @@ SubClassOf( ObjectComplementOf(Object SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) DisjointClasses( ObjectSomeValuesFrom( )) +# Class: (angiogenesis) + +AnnotationAssertion(Annotation( "ISBN:0878932453") "Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels.") +AnnotationAssertion( "Wikipedia:Angiogenesis") +AnnotationAssertion(Annotation( ) "blood vessel formation from pre-existing blood vessels") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0001525") +AnnotationAssertion(rdfs:label "angiogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cilium or flagellum-dependent cell motility) + +AnnotationAssertion(Annotation( "GOC:cilia") Annotation( "GOC:hjd") Annotation( "GOC:krc") "Cell motility due to movement of eukaryotic cilia or bacterial-type flagella or archaeal-type flagella.") +AnnotationAssertion( "ciliary/flagellar motility") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "ciliary or bacterial-type flagellar motility") +AnnotationAssertion( "GO:0001539") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:comment "Note that we deem eukaryotic cilia and microtubule-based flagella to be equivalent, while the bacterial- and archaeal-type flagella have a different structure. The former are microtubule-based structures that lash back and forth and are present only in eukaryotes, while the latter achieve motility by rotation. Bacterial- and archaeal-type flagella are superficially similar but have a different molecular composition and fine structure. These three structures never co-exist in the same organism. Therefore, GO:0001539 'cilium or flagellum-dependent cell motility' is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term. Direct annotations to GO:0001539 'cilium or flagellum-dependent cell motility' may be amended during annotation QC.") +AnnotationAssertion(rdfs:label "cilium or flagellum-dependent cell motility") +SubClassOf( ) + +# Class: (ovarian follicle development) + +AnnotationAssertion(Annotation( "https://www.ncbi.nlm.nih.gov/books/NBK279054/") "The process whose specific outcome is the progression of the ovarian follicle over time, from its formation to the mature structure.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "follicular phase") +AnnotationAssertion( "GO:0001541") +AnnotationAssertion(rdfs:label "ovarian follicle development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (primary ovarian follicle growth) + +AnnotationAssertion(Annotation( "GOC:mtg_mpo") Annotation( "https://www.ncbi.nlm.nih.gov/books/NBK279054/") "Increase in size of primary follicles including oocyte growth and granulosa and/or theca cell proliferation until more than one layer of granulosa cells is present (preantral follicle).") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0001545") +AnnotationAssertion(rdfs:label "primary ovarian follicle growth") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (preantral ovarian follicle growth) + +AnnotationAssertion(Annotation( "https://www.ncbi.nlm.nih.gov/books/NBK279054/") "Increase in size of follicles surrounded by two or more layers of granulosa cells up to the onset of antrum formation.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0001546") +AnnotationAssertion(rdfs:label "preantral ovarian follicle growth") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (antral ovarian follicle growth) + +AnnotationAssertion(Annotation( "https://www.ncbi.nlm.nih.gov/books/NBK279054/") "Increase in size of antral follicles due to cell proliferation and/or growth of the antral cavity.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0001547") +AnnotationAssertion(rdfs:label "antral ovarian follicle growth") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (ovarian cumulus expansion) + +AnnotationAssertion(Annotation( "PMID:30010832") "Increase in size of the cumulus surrounding the oocyte including change in morphology due to proliferation and dispersion of cumulus cells.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "ovarian cumulus growth") +AnnotationAssertion( "GO:0001550") +AnnotationAssertion(rdfs:label "ovarian cumulus expansion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (luteinization) AnnotationAssertion(Annotation( "https://www.ncbi.nlm.nih.gov/books/NBK279054/") "The set of processes resulting in differentiation of theca and granulosa cells into luteal cells and in the formation of a corpus luteum after ovulation.") @@ -27458,6 +45007,232 @@ AnnotationAssertion(rdfs:label "lute SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (oocyte growth) + +AnnotationAssertion(Annotation( "https://www.ncbi.nlm.nih.gov/books/NBK279054/") "The developmental growth process in which an oocyte irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0001555") +AnnotationAssertion(rdfs:label "oocyte growth") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectAllValuesFrom( )) + +# Class: (oocyte maturation) + +AnnotationAssertion(Annotation( "GOC:devbiol") Annotation( "https://www.ncbi.nlm.nih.gov/books/NBK279054/") "A developmental process, independent of morphogenetic (shape) change, that is required for an oocyte to attain its fully functional state. Oocyte maturation commences after reinitiation of meiosis commonly starting with germinal vesicle breakdown, and continues up to the second meiotic arrest prior to fertilization.") +AnnotationAssertion( "Wikipedia:Oocyte_maturation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0001556") +AnnotationAssertion(rdfs:label "oocyte maturation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectAllValuesFrom( )) + +# Class: (regulation of cell growth) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate, extent or direction of cell growth.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0001558") +AnnotationAssertion(rdfs:label "regulation of cell growth") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (blood vessel development) + +AnnotationAssertion(Annotation( "GOC:hjd") Annotation( "UBERON:0001981") "The process whose specific outcome is the progression of a blood vessel over time, from its formation to the mature structure. The blood vessel is the vasculature carrying blood.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0001568") +AnnotationAssertion(rdfs:label "blood vessel development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (branching involved in blood vessel morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") "The process of coordinated growth and sprouting of blood vessels giving rise to the organized vascular system.") +AnnotationAssertion(Annotation( "GOC:dph") "patterning of blood vessels") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0001569") +AnnotationAssertion(rdfs:label "branching involved in blood vessel morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (vasculogenesis) + +AnnotationAssertion(Annotation( "PMID:8999798") "The differentiation of endothelial cells from progenitor cells during blood vessel development, and the de novo formation of blood vessels and tubes.") +AnnotationAssertion( "Wikipedia:Vasculogenesis") +AnnotationAssertion( "vascular morphogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0001570") +AnnotationAssertion(rdfs:label "vasculogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (microtubule bundle formation) + +AnnotationAssertion(Annotation( "GOC:dph") "A process that results in a parallel arrangement of microtubules.") +AnnotationAssertion( "microtubule bundling") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0001578") +AnnotationAssertion(rdfs:label "microtubule bundle formation") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (G protein-coupled adenosine receptor activity) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:mah") Annotation( "PMID:9755289") "Combining with adenosine and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.") +AnnotationAssertion( "GO:0001610") +AnnotationAssertion( "GO:0001611") +AnnotationAssertion( "GO:0001612") +AnnotationAssertion( "GO:0001613") +AnnotationAssertion( "GO:0008501") +AnnotationAssertion( "adenosine nucleotide receptor") +AnnotationAssertion( "G protein coupled adenosine receptor activity") +AnnotationAssertion( "G-protein coupled adenosine receptor activity") +AnnotationAssertion(Annotation( "PMID:9755289") "P1 receptor") +AnnotationAssertion( "adenosine receptor activity, G protein coupled") +AnnotationAssertion(Annotation( "GOC:bf") "adenosine receptor activity, G-protein coupled") +AnnotationAssertion( "A1 adenosine receptor activity, G protein coupled") +AnnotationAssertion( "A1 adenosine receptor activity, G-protein coupled") +AnnotationAssertion( "A2A adenosine receptor activity, G protein coupled") +AnnotationAssertion( "A2A adenosine receptor activity, G-protein coupled") +AnnotationAssertion( "A2B adenosine receptor activity, G protein coupled") +AnnotationAssertion( "A2B adenosine receptor activity, G-protein coupled") +AnnotationAssertion( "A3 adenosine receptor activity, G protein coupled") +AnnotationAssertion( "A3 adenosine receptor activity, G-protein coupled") +AnnotationAssertion( "G protein coupled A1 adenosine receptor activity") +AnnotationAssertion( "G protein coupled A2A adenosine receptor activity") +AnnotationAssertion( "G protein coupled A2B adenosine receptor activity") +AnnotationAssertion( "G protein coupled A3 adenosine receptor activity") +AnnotationAssertion( "G-protein-coupled A1 adenosine receptor activity") +AnnotationAssertion( "G-protein-coupled A2A adenosine receptor activity") +AnnotationAssertion( "G-protein-coupled A2B adenosine receptor activity") +AnnotationAssertion( "G-protein-coupled A3 adenosine receptor activity") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0001609") +AnnotationAssertion(rdfs:label "G protein-coupled adenosine receptor activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (purinergic nucleotide receptor activity) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:signaling") "Combining with a purine nucleotide and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2010-10-22T10:57:12Z") +AnnotationAssertion( "GO:0035586") +AnnotationAssertion(Annotation( "PMID:9755289") "purinoceptor") +AnnotationAssertion(Annotation( "PMID:9755289") "purinoreceptor") +AnnotationAssertion( "molecular_function") +AnnotationAssertion(Annotation( "PMID:9755289") "P2 receptor") +AnnotationAssertion( "purinergic receptor activity") +AnnotationAssertion( "GO:0001614") +AnnotationAssertion(rdfs:label "purinergic nucleotide receptor activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (G protein-coupled ADP receptor activity) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:signaling") Annotation( "PMID:11196645") "Combining with ADP and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.") +AnnotationAssertion( "GO:0045032") +AnnotationAssertion( "ADP receptor activity") +AnnotationAssertion( "ADP-activated nucleotide receptor activity") +AnnotationAssertion( "K101 receptor") +AnnotationAssertion(Annotation( "GOC:mah") "platelet ADP receptor activity") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "ADP-activated adenosine receptor activity") +AnnotationAssertion( "GO:0001621") +AnnotationAssertion(rdfs:label "G protein-coupled ADP receptor activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (osteoblast differentiation) + +AnnotationAssertion(Annotation( "CL:0000062") Annotation( "GOC:jid") Annotation( "GO_REF:0000034") "The process whereby a relatively unspecialized cell acquires the specialized features of an osteoblast, a mesodermal or neural crest cell that gives rise to bone.") +AnnotationAssertion( "osteoblast cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0001649") +AnnotationAssertion(rdfs:label "osteoblast differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (peptide receptor activity) + +AnnotationAssertion(Annotation( "GOC:jl") "Combining with an extracellular or intracellular peptide to initiate a change in cell activity.") +AnnotationAssertion( "endogenous peptide receptor activity") +AnnotationAssertion( "exogenous peptide receptor activity") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0001653") +AnnotationAssertion(rdfs:label "peptide receptor activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (eye development) + +AnnotationAssertion(Annotation( "GOC:jid") Annotation( "GOC:jl") "The process whose specific outcome is the progression of the eye over time, from its formation to the mature structure. The eye is the organ of sight.") +AnnotationAssertion( "GO:0042460") +AnnotationAssertion( "Wikipedia:Eye_development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0001654") +AnnotationAssertion(rdfs:label "eye development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (urogenital system development) + +AnnotationAssertion(Annotation( "GOC:go_curators") "The process whose specific outcome is the progression of the urogenital system over time, from its formation to the mature structure.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/22178"^^xsd:anyURI) +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0001655") +AnnotationAssertion(rdfs:label "urogenital system development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (metanephros development) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "ISBN:0192800752") "The process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. In mammals, the metanephros is the excretory organ of the fetus, which develops into the mature kidney and is formed from the rear portion of the nephrogenic cord. The metanephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0001656") +AnnotationAssertion(rdfs:label "metanephros development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (ureteric bud development) + +AnnotationAssertion(Annotation( "GOC:go_curators") "The process whose specific outcome is the progression of the ureteric bud over time, from its formation to the mature structure.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0001657") +AnnotationAssertion(rdfs:label "ureteric bud development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (branching involved in ureteric bud morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:16916378") "The process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules.") +AnnotationAssertion(Annotation( "GOC:dph") "ureteric bud branching") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0001658") +AnnotationAssertion(rdfs:label "branching involved in ureteric bud morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + # Class: (temperature homeostasis) AnnotationAssertion(Annotation( "GOC:jl") "A homeostatic process in which an organism modulates its internal body temperature.") @@ -27468,6 +45243,19 @@ AnnotationAssertion( "temperature homeostasis") SubClassOf( ) +# Class: (G protein-coupled receptor binding) + +AnnotationAssertion(Annotation( "GOC:ceb") Annotation( "GOC:dph") "Binding to a G protein-coupled receptor.") +AnnotationAssertion(Annotation(rdfs:label "Activation of GRIK3 homomer") "Reactome:R-HSA-500717") +AnnotationAssertion( "G protein coupled receptor binding") +AnnotationAssertion(Annotation( "GOC:bf") "G-protein coupled receptor binding") +AnnotationAssertion( "G protein coupled receptor ligand") +AnnotationAssertion( "G-protein-coupled receptor ligand") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0001664") +AnnotationAssertion(rdfs:label "G protein-coupled receptor binding") +SubClassOf( ) + # Class: (response to hypoxia) AnnotationAssertion(Annotation( "GOC:hjd") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.") @@ -27482,6 +45270,43 @@ AnnotationAssertion(rdfs:label "resp SubClassOf( ) SubClassOf( ) +# Class: (ameboidal-type cell migration) + +AnnotationAssertion(Annotation( "GOC:dph") "Cell migration that is accomplished by extension and retraction of a pseudopodium.") +AnnotationAssertion( "ameboid cell migration") +AnnotationAssertion( "amoeboid cell migration") +AnnotationAssertion( "amoeboidal cell migration") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0001667") +AnnotationAssertion(rdfs:comment "Note that this term refers to a mode of migration rather than to any particular cell type.") +AnnotationAssertion(rdfs:label "ameboidal-type cell migration") +SubClassOf( ) + +# Class: (acrosomal vesicle) + +AnnotationAssertion(Annotation( "ISBN:0124325653") Annotation( "ISBN:0198506732") "A structure in the head of a spermatozoon that contains acid hydrolases, and is concerned with the breakdown of the outer membrane of the ovum during fertilization. It lies just beneath the plasma membrane and is derived from the lysosome.") +AnnotationAssertion( "Wikipedia:Acrosome") +AnnotationAssertion(Annotation( "GOC:sart") "acrosomal granule") +AnnotationAssertion(Annotation( "GOC:dph") "acrosome") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0001669") +AnnotationAssertion(rdfs:label "acrosomal vesicle") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (male germ cell nucleus) + +AnnotationAssertion(Annotation( "CL:0000015") Annotation( "GOC:hjd") Annotation( "GOC:mtg_sensu") "The nucleus of a male germ cell, a reproductive cell in males.") +AnnotationAssertion( "GO:0043081") +AnnotationAssertion( "male germ-cell nucleus") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0001673") +AnnotationAssertion(rdfs:label "male germ cell nucleus") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectAllValuesFrom( )) + # Class: (female germ cell nucleus) AnnotationAssertion(Annotation( "CL:0000021") Annotation( "GOC:hjd") "The nucleus of the female germ cell, a reproductive cell in females.") @@ -27490,10 +45315,24 @@ AnnotationAssertion( "cellular_component") AnnotationAssertion( "GO:0001674") AnnotationAssertion(rdfs:label "female germ cell nucleus") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectAllValuesFrom( )) +# Class: (acrosome assembly) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:hjd") Annotation( "GOC:tb") "The formation of the acrosome from the spermatid Golgi.") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "acrosome formation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0001675") +AnnotationAssertion(rdfs:label "acrosome assembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (formation of translation initiation ternary complex) AnnotationAssertion(Annotation( "GOC:hjd") "Formation of a complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2 (either eIF2 in eukaryotes, or IF2 in prokaryotes). In prokaryotes, fMet-tRNA (initiator) is used rather than Met-tRNA (initiator).") @@ -27501,9 +45340,20 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0001677") AnnotationAssertion(rdfs:label "formation of translation initiation ternary complex") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (intracellular glucose homeostasis) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:go_curators") Annotation( "GOC:tb") "A homeostatic process involved in the maintenance of a steady state level of glucose within a cell.") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "cell glucose homeostasis") +AnnotationAssertion( "cellular glucose homeostasis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0001678") +AnnotationAssertion(rdfs:label "intracellular glucose homeostasis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (histamine metabolic process) AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0395825172") "The chemical reactions and pathways involving histamine, a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans.") @@ -27511,6 +45361,7 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0001692") AnnotationAssertion(rdfs:label "histamine metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ) @@ -27539,7 +45390,6 @@ AnnotationAssertion( "GO:0001695") AnnotationAssertion(rdfs:label "histamine catabolic process") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) SubClassOf( ) # Class: (gastric acid secretion) @@ -27553,6 +45403,16 @@ SubClassOf( ) SubClassOf( ) +# Class: (embryonic development via the syncytial blastoderm) + +AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "GOC:mtg_sensu") "The process whose specific outcome is the progression of the embryo over time, from zygote formation through syncytial blastoderm to the hatching of the first instar larva. An example of this process is found in Drosophila melanogaster.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0001700") +AnnotationAssertion(rdfs:label "embryonic development via the syncytial blastoderm") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectAllValuesFrom( )) + # Class: (in utero embryonic development) AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "GOC:mtg_sensu") "The process whose specific outcome is the progression of the embryo in the uterus over time, from formation of the zygote in the oviduct, to birth. An example of this process is found in Mus musculus.") @@ -27563,12 +45423,37 @@ SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectAllValuesFrom( )) +# Class: (gastrulation with mouth forming second) + +AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "GOC:mtg_sensu") "A gastrulation process in which the initial invagination becomes the anus and the mouth forms second.") +AnnotationAssertion( "GO:0010003") +AnnotationAssertion( "GO:0048276") +AnnotationAssertion(Annotation( "GOC:dph") "deuterostomic gastrulation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0001702") +AnnotationAssertion(rdfs:label "gastrulation with mouth forming second") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectAllValuesFrom( )) + +# Class: (gastrulation with mouth forming first) + +AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "GOC:mtg_sensu") "A gastrulation process in which the initial invagination becomes the mouth and the anus forms second.") +AnnotationAssertion(Annotation( "GOC:dph") "protostomic gastrulation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0001703") +AnnotationAssertion(rdfs:label "gastrulation with mouth forming first") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectAllValuesFrom( )) + # Class: (formation of primary germ layer) AnnotationAssertion(Annotation( "GOC:go_curators") "The formation of the ectoderm, mesoderm and endoderm during gastrulation.") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0001704") AnnotationAssertion(rdfs:label "formation of primary germ layer") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) @@ -27579,6 +45464,7 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:0001705") AnnotationAssertion(rdfs:label "ectoderm formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) @@ -27589,6 +45475,7 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:0001706") AnnotationAssertion(rdfs:label "endoderm formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) @@ -27598,9 +45485,73 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:0001707") AnnotationAssertion(rdfs:label "mesoderm formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (morphogenesis of a polarized epithelium) + +AnnotationAssertion(Annotation( "GOC:dph") "The morphogenetic process in which the anatomical structures of a polarized epithelium are generated and organized. A polarized epithelium is an epithelium where the epithelial sheet is oriented with respect to the planar axis.") +AnnotationAssertion(Annotation( "GOC:dph") "epithelial polarization") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0001738") +AnnotationAssertion(rdfs:label "morphogenesis of a polarized epithelium") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (lens placode formation) + +AnnotationAssertion(Annotation( "GOC:dph") "The initial developmental process that will lead to the formation of an eye.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "optic placode formation") +AnnotationAssertion( "GO:0001743") +AnnotationAssertion(rdfs:label "lens placode formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (insect visual primordium formation) + +AnnotationAssertion(Annotation( "GOC:mtg_sensu") Annotation( "PMID:8402833") "Establishment of the optic lobe placode. In Drosophila, for example, the placode appears in the dorsolateral region of the head in late stage 11 embryos and is the precursor to the larval visual system.") +AnnotationAssertion( "GO:0007457") +AnnotationAssertion( "optic lobe and Bolwig's organ precursor formation") +AnnotationAssertion( "optic lobe placode formation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0001744") +AnnotationAssertion(rdfs:label "insect visual primordium formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (compound eye morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_sensu") "The morphogenetic process in which the anatomical structures of the compound eye are generated and organized. The adult compound eye is a precise assembly of 700-800 ommatidia. Each ommatidium is composed of 20 cells, identified by cell type and position. An example of compound eye morphogenesis is found in Drosophila melanogaster.") +AnnotationAssertion(Annotation( "PMID:11735386") "insect-type retina morphogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0001745") +AnnotationAssertion(rdfs:label "compound eye morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectAllValuesFrom( )) + +# Class: (insect visual primordium development) + +AnnotationAssertion(Annotation( "GOC:mtg_sensu") Annotation( "PMID:8402833") "The process whose specific outcome is the progression of the optic placode over time, from its formation to the mature structure. During embryonic stage 12 the placode starts to invaginate, forming a pouch. Cells that will form Bolwig's organ segregate from the ventral lip of this pouch, remaining in the head epidermis. The remainder of the invagination loses contact with the outer surface and becomes the optic lobe. An example of this process is found in Drosophila melanogaster.") +AnnotationAssertion( "GO:0048049") +AnnotationAssertion( "optic placode development") +AnnotationAssertion( "optic lobe and Bolwig's organ precursor development") +AnnotationAssertion( "optic lobe placode development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0001748") +AnnotationAssertion(rdfs:label "insect visual primordium development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectAllValuesFrom( )) + # Class: (photoreceptor outer segment) AnnotationAssertion(Annotation( "GOC:cilia") Annotation( "GOC:krc") Annotation( "GOC:pde") Annotation( "ISBN:0824072820") Annotation( "PMID:19501669") Annotation( "PMID:26574505") Annotation( "PMID:6771304") "The outer segment of a vertebrate photoreceptor that contains a stack of membrane discs embedded with photoreceptor proteins.") @@ -27613,6 +45564,52 @@ SubClassOf( ObjectSomeValuesFrom( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (compound eye photoreceptor cell differentiation) + +AnnotationAssertion(Annotation( "GOC:go_curators") "The process in which a relatively unspecialized cell acquires the specialized features of an eye photoreceptor cell.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0001751") +AnnotationAssertion(rdfs:label "compound eye photoreceptor cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (eye photoreceptor cell differentiation) + +AnnotationAssertion(Annotation( "GOC:go_curators") "The process in which a relatively unspecialized cell acquires the specialized features of a photoreceptor cell, as found in the eye, the primary visual organ of most organisms.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0001754") +AnnotationAssertion(rdfs:label "eye photoreceptor cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (neural crest cell migration) + +AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") Annotation( "ISBN:0878932437") "The characteristic movement of cells from the dorsal ridge of the neural tube to a variety of locations in a vertebrate embryo.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0001755") +AnnotationAssertion(rdfs:label "neural crest cell migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (somitogenesis) + +AnnotationAssertion(Annotation( "ISBN:0721662544") "The formation of mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo.") +AnnotationAssertion( "Wikipedia:Somitogenesis") +AnnotationAssertion(Annotation( ) "formation of mesodermal clusters") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0001756") +AnnotationAssertion(rdfs:label "somitogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (morphogenesis of a branching structure) AnnotationAssertion(Annotation( "ISBN:0721662544") "The process in which the anatomical structures of branches are generated and organized. A branch is a division or offshoot from a main stem. Examples in animals would include blood vessels, nerves, lymphatics and other endothelial or epithelial tubes.") @@ -27624,6 +45621,74 @@ SubClassOf( ) SubClassOf( ) +# Class: (neuron migration) + +AnnotationAssertion(Annotation( "CL:0000540") Annotation( "GOC:go_curators") "The characteristic movement of an immature neuron from germinal zones to specific positions where they will reside as they mature.") +AnnotationAssertion( "Wikipedia:Neural_development#Neuron_migration") +AnnotationAssertion( "Wikipedia:Neuron_migration") +AnnotationAssertion( "neuron chemotaxis") +AnnotationAssertion( "neuronal migration") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "neuron guidance") +AnnotationAssertion( "GO:0001764") +AnnotationAssertion(rdfs:label "neuron migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (establishment of lymphocyte polarity) + +AnnotationAssertion(Annotation( "GOC:mgi_curators") Annotation( "PMID:11244041") Annotation( "PMID:12615889") "The directed orientation of lymphocyte signaling molecules and associated membrane rafts towards a chemokine gradient or a contact point with an appropriate activating cell.") +AnnotationAssertion( "lymphocyte polarization") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0001767") +AnnotationAssertion(rdfs:label "establishment of lymphocyte polarity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (establishment of T cell polarity) + +AnnotationAssertion(Annotation( "GOC:mgi_curators") Annotation( "PMID:11244041") Annotation( "PMID:12615889") "The directed orientation of T cell signaling molecules and associated membrane rafts towards a chemokine gradient or a contact point with antigen presenting cell.") +AnnotationAssertion( "T cell polarization") +AnnotationAssertion( "T lymphocyte polarization") +AnnotationAssertion( "T-cell polarization") +AnnotationAssertion( "establishment of T lymphocyte polarity") +AnnotationAssertion( "establishment of T-cell polarity") +AnnotationAssertion( "establishment of T-lymphocyte polarity") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0001768") +AnnotationAssertion(rdfs:label "establishment of T cell polarity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (establishment of B cell polarity) + +AnnotationAssertion(Annotation( "GOC:mgi_curators") Annotation( "PMID:12615889") Annotation( "PMID:9692889") "The directed orientation of B cell signaling molecules and associated membrane rafts towards a chemokine gradient of a contact point with an antigen displaying cell.") +AnnotationAssertion( "B cell polarization") +AnnotationAssertion( "B lymphocyte polarization") +AnnotationAssertion( "B-cell polarization") +AnnotationAssertion( "establishment of B lymphocyte polarity") +AnnotationAssertion( "establishment of B-cell polarity") +AnnotationAssertion( "establishment of B-lymphocyte polarity") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0001769") +AnnotationAssertion(rdfs:comment "Note that 'antigen displaying cell' in this term encompasses cell types such as follicular dendritic cells which display the unprocessed antigens of a B cell, leading to activation of the B cells and antigen uptake and processing by the B cells.") +AnnotationAssertion(rdfs:label "establishment of B cell polarity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (myeloid dendritic cell activation) + +AnnotationAssertion(Annotation( "GOC:mgi_curators") Annotation( "ISBN:0781735149") "The change in morphology and behavior of a dendritic cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0001773") +AnnotationAssertion(rdfs:label "myeloid dendritic cell activation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + # Class: (cell activation) AnnotationAssertion(Annotation( "GOC:mgi_curators") "A multicellular organismal process by which exposure to an activating factor such as a cellular or soluble ligand results in a change in the morphology or behavior of a cell.") @@ -27637,6 +45702,186 @@ SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectAllValuesFrom( )) +# Class: (leukocyte homeostasis) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") "The process of regulating the proliferation and elimination of cells of the immune system such that the total number of cells of a particular cell type within a whole or part of an organism is stable over time in the absence of an outside stimulus.") +AnnotationAssertion( "immune cell homeostasis") +AnnotationAssertion( "leucocyte homeostasis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0001776") +AnnotationAssertion(rdfs:comment "Note that this term represents the return of immune system cell levels to stable numbers following an immune response as well as the proliferation and elimination of cells of the immune system required to maintain stable numbers in the absence of an outside stimulus.") +AnnotationAssertion(rdfs:label "leukocyte homeostasis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectAllValuesFrom( )) + +# Class: (T cell homeostatic proliferation) + +AnnotationAssertion(Annotation( "GOC:mgi_curators") Annotation( "ISBN:0781735149") "The non-specific expansion of T cell populations within a whole or part of an organism to reach to a total number of T cells which will then remain stable over time in the absence of an external stimulus.") +AnnotationAssertion( "T lymphocyte homeostatic proliferation") +AnnotationAssertion( "T-cell homeostatic proliferation") +AnnotationAssertion( "T-lymphocyte homeostatic proliferation") +AnnotationAssertion( "resting T cell proliferation") +AnnotationAssertion( "resting T-cell proliferation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0001777") +AnnotationAssertion(rdfs:label "T cell homeostatic proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (neutrophil homeostasis) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:pr") Annotation( "PMID:12752675") Annotation( "PMID:12960266") "The process of regulating the proliferation and elimination of neutrophils such that the total number of neutrophils within a whole or part of an organism is stable over time in the absence of an outside stimulus.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0001780") +AnnotationAssertion(rdfs:comment "Note that this term represents the return of neutrophil levels to stable numbers following an immune response as well as the proliferation and elimination of neutrophils required to maintain stable numbers in the absence of an outside stimulus.") +AnnotationAssertion(rdfs:label "neutrophil homeostasis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (neutrophil apoptotic process) + +AnnotationAssertion(Annotation( "CL:0000775") Annotation( "GOC:add") Annotation( "GOC:mtg_apoptosis") Annotation( "PMID:12752675") Annotation( "PMID:12960266") "Any apoptotic process in a neutrophil, any of the immature or mature forms of a granular leukocyte that in its mature form has a nucleus with three to five lobes connected by slender threads of chromatin, and cytoplasm containing fine inconspicuous granules and stainable by neutral dyes.") +AnnotationAssertion( "apoptosis of neutrophils") +AnnotationAssertion( "neutrophil programmed cell death by apoptosis") +AnnotationAssertion( "programmed cell death of neutrophils by apoptosis") +AnnotationAssertion( "programmed cell death, neutrophils") +AnnotationAssertion( "neutrophil apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0001781") +AnnotationAssertion(rdfs:label "neutrophil apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (B cell homeostasis) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") Annotation( "PMID:12956429") "The process of regulating the proliferation and elimination of B cells such that the total number of B cells within a whole or part of an organism is stable over time in the absence of an outside stimulus.") +AnnotationAssertion( "B lymphocyte homeostasis") +AnnotationAssertion( "B-cell homeostasis") +AnnotationAssertion( "B-lymphocyte homeostasis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0001782") +AnnotationAssertion(rdfs:comment "Note that this term represents the return of B cell levels to stable numbers following an immune response as well as the proliferation and elimination of B cells required to maintain stable numbers in the absence of an outside stimulus.") +AnnotationAssertion(rdfs:label "B cell homeostasis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (B cell apoptotic process) + +AnnotationAssertion(Annotation( "CL:0000236") Annotation( "GOC:add") Annotation( "GOC:mtg_apoptosis") Annotation( "ISBN:0781735149") "Any apoptotic process in a B cell, a lymphocyte of B lineage with the phenotype CD19-positive and capable of B cell mediated immunity.") +AnnotationAssertion( "B cell programmed cell death by apoptosis") +AnnotationAssertion( "B lymphocyte apoptosis") +AnnotationAssertion( "B lymphocyte programmed cell death by apoptosis") +AnnotationAssertion( "B-cell apoptosis") +AnnotationAssertion( "B-cell programmed cell death by apoptosis") +AnnotationAssertion( "B-lymphocyte apoptosis") +AnnotationAssertion( "B-lymphocyte programmed cell death by apoptosis") +AnnotationAssertion( "apoptosis of B cells") +AnnotationAssertion( "apoptosis of B lymphocytes") +AnnotationAssertion( "apoptosis of B-cells") +AnnotationAssertion( "apoptosis of B-lymphocytes") +AnnotationAssertion( "programmed cell death of B cells by apoptosis") +AnnotationAssertion( "programmed cell death of B lymphocytes by apoptosis") +AnnotationAssertion( "programmed cell death of B-cells by apoptosis") +AnnotationAssertion( "programmed cell death of B-lymphocytes by apoptosis") +AnnotationAssertion( "programmed cell death, B cells") +AnnotationAssertion( "programmed cell death, B lymphocytes") +AnnotationAssertion( "programmed cell death, B-cells") +AnnotationAssertion( "programmed cell death, B-lymphocytes") +AnnotationAssertion( "B cell apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0001783") +AnnotationAssertion(rdfs:label "B cell apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (cytokine production) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") "The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/19116"^^xsd:anyURI) +AnnotationAssertion( "GO:0042032") +AnnotationAssertion( "GO:0042089") +AnnotationAssertion( "GO:0042107") +AnnotationAssertion( "GO:0050663") +AnnotationAssertion( "cytokine biosynthetic process") +AnnotationAssertion( "cytokine metabolic process") +AnnotationAssertion( "cytokine secretion") +AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:mah") "interferon production") +AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:mah") "interferon secretion") +AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:mah") Annotation( "http://wiki.geneontology.org/index.php/Why_isn%27t_interleukin_in_GO%3F") "interleukin production") +AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:mah") Annotation( "http://wiki.geneontology.org/index.php/Why_isn%27t_interleukin_in_GO%3F") "interleukin secretion") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0001816") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.") +AnnotationAssertion(rdfs:label "cytokine production") +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of cytokine production) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") "Any process that modulates the frequency, rate, or extent of production of a cytokine.") +AnnotationAssertion( "GO:0042035") +AnnotationAssertion( "GO:0050707") +AnnotationAssertion( "regulation of cytokine anabolism") +AnnotationAssertion( "regulation of cytokine biosynthesis") +AnnotationAssertion( "regulation of cytokine formation") +AnnotationAssertion( "regulation of cytokine synthesis") +AnnotationAssertion( "regulation of cytokine biosynthetic process") +AnnotationAssertion( "regulation of cytokine secretion") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0001817") +AnnotationAssertion(rdfs:label "regulation of cytokine production") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of cytokine production) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") "Any process that stops, prevents, or reduces the rate of production of a cytokine.") +AnnotationAssertion( "GO:0042036") +AnnotationAssertion( "GO:0050710") +AnnotationAssertion( "down regulation of cytokine biosynthetic process") +AnnotationAssertion( "down regulation of cytokine production") +AnnotationAssertion( "down-regulation of cytokine biosynthetic process") +AnnotationAssertion( "down-regulation of cytokine production") +AnnotationAssertion( "downregulation of cytokine biosynthetic process") +AnnotationAssertion( "downregulation of cytokine production") +AnnotationAssertion( "negative regulation of cytokine anabolism") +AnnotationAssertion( "negative regulation of cytokine biosynthesis") +AnnotationAssertion( "negative regulation of cytokine formation") +AnnotationAssertion( "negative regulation of cytokine synthesis") +AnnotationAssertion( "inhibition of cytokine biosynthetic process") +AnnotationAssertion( "inhibition of cytokine production") +AnnotationAssertion( "negative regulation of cytokine biosynthetic process") +AnnotationAssertion( "negative regulation of cytokine secretion") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0001818") +AnnotationAssertion(rdfs:label "negative regulation of cytokine production") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of cytokine production) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") "Any process that activates or increases the frequency, rate or extent of production of a cytokine.") +AnnotationAssertion( "GO:0042108") +AnnotationAssertion( "GO:0050715") +AnnotationAssertion( "up regulation of cytokine production") +AnnotationAssertion( "up-regulation of cytokine production") +AnnotationAssertion( "upregulation of cytokine production") +AnnotationAssertion( "activation of cytokine production") +AnnotationAssertion( "positive regulation of cytokine biosynthetic process") +AnnotationAssertion( "positive regulation of cytokine secretion") +AnnotationAssertion( "stimulation of cytokine production") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0001819") +AnnotationAssertion(rdfs:label "positive regulation of cytokine production") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (serotonin secretion) AnnotationAssertion(Annotation( "GOC:ef") Annotation( "ISBN:0198506732") Annotation( "ISBN:0781735149") "The regulated release of serotonin by a cell. Serotonin (5-hydroxytryptamine, or 5-HT) is a monoamine synthesised in serotonergic neurons in the central nervous system, enterochromaffin cells in the gastrointestinal tract and some immune system cells.") @@ -27646,10 +45891,151 @@ AnnotationAssertion( "GOC:tb") "serotonin release") AnnotationAssertion( "GO:0001820") AnnotationAssertion(rdfs:label "serotonin secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ) +# Class: (histamine secretion) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "ISBN:0198506732") Annotation( "ISBN:0781735149") "The regulated release of histamine by a cell or tissue. It is formed by decarboxylation of histidine and it acts through receptors in smooth muscle and in secretory systems.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0001821") +AnnotationAssertion(rdfs:label "histamine secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (kidney development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_kidney_jan10") Annotation( "ISBN:0124020607") Annotation( "ISBN:0721662544") "The process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and/or excretes the end products of body metabolism in the form of urine.") +AnnotationAssertion( "Wikipedia:Kidney_development") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:rph") "nephrogenesis") +AnnotationAssertion( "GO:0001822") +AnnotationAssertion(rdfs:label "kidney development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (mesonephros development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "ISBN:0124020607") Annotation( "ISBN:0721662544") Annotation( "PMID:10535314") "The process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. In mammals, the mesonephros is the second of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the mesonephros will form the mature kidney.") +AnnotationAssertion(Annotation( "GOC:dph") "Wolffian body development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0001823") +AnnotationAssertion(rdfs:label "mesonephros development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (blastocyst development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "ISBN:0124020607") Annotation( "ISBN:0198542771") "The process whose specific outcome is the progression of the blastocyst over time, from its formation to the mature structure. The mammalian blastocyst is a hollow ball of cells containing two cell types, the inner cell mass and the trophectoderm.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0001824") +AnnotationAssertion(rdfs:comment "See also the Anatomical Dictionary for Mouse Development ontology terms 'TS5, embryo ; EMAP:23', 'TS5, inner cell mass ; EMAP:24' and 'TS5, trophectoderm; EMAP:28'.") +AnnotationAssertion(rdfs:label "blastocyst development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectAllValuesFrom( )) + +# Class: (blastocyst formation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "ISBN:0124020607") Annotation( "ISBN:0198542771") "The initial formation of a blastocyst from a solid ball of cells known as a morula.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0001825") +AnnotationAssertion(rdfs:comment "See also the Anatomical Dictionary for Mouse Development ontology term 'TS3, compacted morula ; EMAP:9'.") +AnnotationAssertion(rdfs:label "blastocyst formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (inner cell mass cell differentiation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "ISBN:0124020607") Annotation( "ISBN:0198542771") "The process in which a relatively unspecialized cell acquires specialized features of an inner cell mass cell.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0001826") +AnnotationAssertion(rdfs:comment "See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, inner cell mass ; EMAP:14'.") +AnnotationAssertion(rdfs:label "inner cell mass cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (trophectodermal cell differentiation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "ISBN:0124020607") Annotation( "ISBN:0198542771") "The process in which a relatively unspecialized cell acquires the specialized features of a trophectoderm cell.") +AnnotationAssertion( "trophectoderm cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0001829") +AnnotationAssertion(rdfs:comment "See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, trophectoderm ; EMAP:19'.") +AnnotationAssertion(rdfs:label "trophectodermal cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (trophectodermal cellular morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "ISBN:0124020607") Annotation( "ISBN:0198542771") "The morphogenesis of trophectoderm cells.") +AnnotationAssertion( "trophectoderm cellular morphogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0001831") +AnnotationAssertion(rdfs:comment "See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, trophectoderm ; EMAP:19', 'TS5, trophectoderm ; EMAP:28' and 'TS6, trophectoderm ; EMAP:39'.") +AnnotationAssertion(rdfs:label "trophectodermal cellular morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (blastocyst growth) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "ISBN:0124020607") Annotation( "ISBN:0198542771") "An increase in size of a blastocyst due to expansion of the blastocoelic cavity cell shape changes and cell proliferation.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0001832") +AnnotationAssertion(rdfs:comment "See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, blastocoelic cavity ; EMAP:17', 'TS5, blastocoelic cavity ; EMAP:27' and 'TS6, blastocoelic cavity ; EMAP:36'.") +AnnotationAssertion(rdfs:label "blastocyst growth") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (inner cell mass cell proliferation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:isa_complete") Annotation( "ISBN:0124020607") Annotation( "ISBN:0198542771") "The proliferation of cells in the inner cell mass.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0001833") +AnnotationAssertion(rdfs:comment "See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, inner cell mass ; EMAP:14' and 'TS5, inner cell mass ; EMAP:24'.") +AnnotationAssertion(rdfs:label "inner cell mass cell proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (trophectodermal cell proliferation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "ISBN:0124020607") Annotation( "ISBN:0198542771") "The proliferation of cells in the trophectoderm.") +AnnotationAssertion( "trophectoderm cell proliferation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0001834") +AnnotationAssertion(rdfs:comment "See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, trophectoderm ; EMAP:19', 'TS5, trophectoderm ; EMAP:28' and 'TS6, trophectoderm ; EMAP:39'.") +AnnotationAssertion(rdfs:label "trophectodermal cell proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (epithelial to mesenchymal transition) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:14701881") "A transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.") +AnnotationAssertion( "EMT") +AnnotationAssertion( "epithelial-mesenchymal transition") +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:rl") "mesenchymal cell differentiation from epithelial cell") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0001837") +AnnotationAssertion(rdfs:label "epithelial to mesenchymal transition") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (embryonic epithelial tube formation) AnnotationAssertion(Annotation( "GOC:dph") Annotation( "ISBN:0824072820") "The morphogenesis of an embryonic epithelium into a tube-shaped structure.") @@ -27659,6 +46045,26 @@ AnnotationAssertion(rdfs:label "embr SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (neural plate morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "ISBN:0878932437") "The process in which the anatomical structures of the neural plate are generated and organized. The neural plate is a specialized region of columnar epithelial cells in the dorsal ectoderm that will give rise to nervous system tissue.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0001839") +AnnotationAssertion(rdfs:label "neural plate morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (neural plate development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:ef") Annotation( "ISBN:0878932437") Annotation( "ISBN:0878932585") "The process whose specific outcome is the progression of the neural plate over time, from its formation to the mature structure. The neural plate is a flat, thickened layer of ectodermal cells. The underlying dorsal mesoderm signals the ectodermal cells above it to elongate into columnar neural plate cells. The neural plate subsequently develops into the neural tube, which gives rise to the central nervous system.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0001840") +AnnotationAssertion(rdfs:label "neural plate development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (neural tube formation) AnnotationAssertion(Annotation( "GOC:dph") Annotation( "ISBN:0878932437") "The formation of a tube from the flat layer of ectodermal cells known as the neural plate. This will give rise to the central nervous system.") @@ -27669,18 +46075,152 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0001841") AnnotationAssertion(rdfs:label "neural tube formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (neural fold formation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "ISBN:0878932437") "The process in which the neural fold is formed. The edges of the neural plate thicken and move up to form a U-shaped structure called the neural groove.") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") "neural groove formation") +AnnotationAssertion( "GO:0001842") +AnnotationAssertion(rdfs:label "neural fold formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (neural tube closure) AnnotationAssertion(Annotation( "GOC:dph") Annotation( "ISBN:0878932437") "The last step in the formation of the neural tube, where the paired neural folds are brought together and fuse at the dorsal midline.") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0001843") AnnotationAssertion(rdfs:label "neural tube closure") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (polysaccharide immune receptor activity) + +AnnotationAssertion(Annotation( "PMID:14707091") "Combining with a polysaccharide and transmitting the signal to initiate an innate immune response. A polysaccharide is a polymer of many (typically more than 10) monosaccharide residues linked glycosidically.") +AnnotationAssertion( "polysaccharide receptor activity") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0001873") +AnnotationAssertion(rdfs:label "polysaccharide immune receptor activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (response to yeast) + +AnnotationAssertion(Annotation( "PMID:14707091") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a yeast species.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0001878") +AnnotationAssertion(rdfs:comment "defined as response to Saccharomycotina (true yeasts). This excludes fission yeast.") +AnnotationAssertion(rdfs:label "response to yeast") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (nucleoside binding) + +AnnotationAssertion(Annotation( "GOC:hjd") "Binding to a nucleoside, a compound consisting of a purine or pyrimidine nitrogenous base linked either to ribose or deoxyribose.") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0001882") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "nucleoside binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (purine nucleoside binding) + +AnnotationAssertion(Annotation( "GOC:hjd") "Binding to a purine nucleoside, a compound consisting of a purine base linked either to ribose or deoxyribose.") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0001883") +AnnotationAssertion(rdfs:label "purine nucleoside binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (endothelial cell development) + +AnnotationAssertion(Annotation( "GOC:dph") "The progression of an endothelial cell over time, from its formation to the mature structure.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0001885") +AnnotationAssertion(rdfs:label "endothelial cell development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (endothelial cell morphogenesis) + +AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "The change in form (cell shape and size) that occurs during the differentiation of an endothelial cell.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0001886") +AnnotationAssertion(rdfs:label "endothelial cell morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (liver development) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:068340007X") "The process whose specific outcome is the progression of the liver over time, from its formation to the mature structure. The liver is an exocrine gland which secretes bile and functions in metabolism of protein and carbohydrate and fat, synthesizes substances involved in the clotting of the blood, synthesizes vitamin A, detoxifies poisonous substances, stores glycogen, and breaks down worn-out erythrocytes.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0001889") +AnnotationAssertion(rdfs:label "liver development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (placenta development) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:068340007X") "The process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin.") +AnnotationAssertion( "placental development") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "placentation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0001890") +AnnotationAssertion(rdfs:label "placenta development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectAllValuesFrom( )) + +# Class: (embryonic placenta development) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:068340007X") "The embryonically driven process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin.") +AnnotationAssertion(Annotation( "GOC:dph") "fetal placenta development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0001892") +AnnotationAssertion(rdfs:label "embryonic placenta development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (maternal placenta development) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:068340007X") "Maternally driven process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin.") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") "decidua development") +AnnotationAssertion( "GO:0001893") +AnnotationAssertion(rdfs:label "maternal placenta development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (tissue homeostasis) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:isa_complete") "A homeostatic process involved in the maintenance of an internal steady state within a defined tissue of an organism, including control of cellular proliferation and death and control of metabolic function.") +AnnotationAssertion(Annotation( "GOC:add") "tissue maintenance") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0001894") +AnnotationAssertion(rdfs:label "tissue homeostasis") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (photoreceptor inner segment) AnnotationAssertion(Annotation( "GOC:add") Annotation( "PMID:12019563") "The inner segment of a vertebrate photoreceptor containing mitochondria, ribosomes and membranes where opsin molecules are assembled and passed to be part of the outer segment discs.") @@ -27692,6 +46232,185 @@ SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (regulation of protein phosphorylation) + +AnnotationAssertion(Annotation( "GOC:hjd") "Any process that modulates the frequency, rate or extent of addition of phosphate groups into an amino acid in a protein.") +AnnotationAssertion(Annotation( "GOC:bf") "regulation of protein amino acid phosphorylation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0001932") +AnnotationAssertion(rdfs:label "regulation of protein phosphorylation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of protein phosphorylation) + +AnnotationAssertion(Annotation( "GOC:hjd") "Any process that stops, prevents or reduces the rate of addition of phosphate groups to amino acids within a protein.") +AnnotationAssertion( "down regulation of protein amino acid phosphorylation") +AnnotationAssertion( "down-regulation of protein amino acid phosphorylation") +AnnotationAssertion( "downregulation of protein amino acid phosphorylation") +AnnotationAssertion(Annotation( "GOC:bf") "negative regulation of protein amino acid phosphorylation") +AnnotationAssertion( "inhibition of protein amino acid phosphorylation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0001933") +AnnotationAssertion(rdfs:label "negative regulation of protein phosphorylation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of protein phosphorylation) + +AnnotationAssertion(Annotation( "GOC:hjd") "Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to amino acids within a protein.") +AnnotationAssertion(Annotation( "GOC:bf") "positive regulation of protein amino acid phosphorylation") +AnnotationAssertion( "up regulation of protein amino acid phosphorylation") +AnnotationAssertion( "up-regulation of protein amino acid phosphorylation") +AnnotationAssertion( "upregulation of protein amino acid phosphorylation") +AnnotationAssertion( "activation of protein amino acid phosphorylation") +AnnotationAssertion( "stimulation of protein amino acid phosphorylation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0001934") +AnnotationAssertion(rdfs:label "positive regulation of protein phosphorylation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (endothelial cell proliferation) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") "The multiplication or reproduction of endothelial cells, resulting in the expansion of a cell population. Endothelial cells are thin flattened cells which line the inside surfaces of body cavities, blood vessels, and lymph vessels, making up the endothelium.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0001935") +AnnotationAssertion(rdfs:label "endothelial cell proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of endothelial cell proliferation) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that modulates the frequency, rate, or extent of endothelial cell proliferation.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0001936") +AnnotationAssertion(rdfs:label "regulation of endothelial cell proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of endothelial cell proliferation) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that stops, prevents, or reduces the rate or extent of endothelial cell proliferation.") +AnnotationAssertion( "down regulation of endothelial cell proliferation") +AnnotationAssertion( "down-regulation of endothelial cell proliferation") +AnnotationAssertion( "downregulation of endothelial cell proliferation") +AnnotationAssertion( "inhibition of endothelial cell proliferation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0001937") +AnnotationAssertion(rdfs:label "negative regulation of endothelial cell proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of endothelial cell proliferation) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that activates or increases the rate or extent of endothelial cell proliferation.") +AnnotationAssertion( "up regulation of endothelial cell proliferation") +AnnotationAssertion( "up-regulation of endothelial cell proliferation") +AnnotationAssertion( "upregulation of endothelial cell proliferation") +AnnotationAssertion( "activation of endothelial cell proliferation") +AnnotationAssertion( "stimulation of endothelial cell proliferation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0001938") +AnnotationAssertion(rdfs:label "positive regulation of endothelial cell proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (male pronucleus) + +AnnotationAssertion(Annotation( "GOC:hjd") Annotation( "ISBN:0198506732") "The pronucleus originating from the spermatozoa that was involved in fertilization.") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0001940") +AnnotationAssertion(rdfs:label "male pronucleus") +SubClassOf( ) + +# Class: (postsynaptic membrane organization) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:pr") "A process which results in the assembly, arrangement of constituent parts, or disassembly of a postsynaptic membrane, the specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft).") +AnnotationAssertion( "post-synaptic membrane organization") +AnnotationAssertion( "postsynaptic membrane organisation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0001941") +AnnotationAssertion(rdfs:label "postsynaptic membrane organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (hair follicle development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "UBERON:0002073") "The process whose specific outcome is the progression of the hair follicle over time, from its formation to the mature structure. A hair follicle is a tube-like opening in the epidermis where the hair shaft develops and into which the sebaceous glands open.") +AnnotationAssertion( "GO:0001943") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0001942") +AnnotationAssertion(rdfs:label "hair follicle development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (vasculature development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "UBERON:0002409") "The process whose specific outcome is the progression of the vasculature over time, from its formation to the mature structure. The vasculature is an interconnected tubular multi-tissue structure that contains fluid that is actively transported around the organism.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "vascular system development") +AnnotationAssertion( "GO:0001944") +AnnotationAssertion(rdfs:label "vasculature development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (lymph vessel development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "UBERON:0001473") "The process whose specific outcome is the progression of a lymph vessel over time, from its formation to the mature structure.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0001945") +AnnotationAssertion(rdfs:label "lymph vessel development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (lymphangiogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:11596157") "Lymph vessel formation when new vessels emerge from the proliferation of pre-existing vessels.") +AnnotationAssertion( "Wikipedia:Lymphangiogenesis") +AnnotationAssertion(Annotation( ) "lymph vessel formation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0001946") +AnnotationAssertion(rdfs:label "lymphangiogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (sebaceous gland cell differentiation) + +AnnotationAssertion(Annotation( "GOC:mgi_curators") Annotation( "PMID:15737203") "The process in which a relatively unspecialized epidermal cell acquires the specialized features of a sebaceous gland cell.") +AnnotationAssertion(Annotation( "GOC:mgi_curators") "sebocytes differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0001949") +AnnotationAssertion(rdfs:label "sebaceous gland cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (blood vessel maturation) + +AnnotationAssertion(Annotation( "GOC:dph") "A developmental process, independent of morphogenetic (shape) change, that is required for a blood vessel to attain its fully functional state.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0001955") +AnnotationAssertion(rdfs:label "blood vessel maturation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (positive regulation of neurotransmitter secretion) + +AnnotationAssertion(Annotation( "GOC:hjd") "Any process that activates or increases the frequency, rate or extent of the regulated release of a neurotransmitter.") +AnnotationAssertion( "up regulation of neurotransmitter secretion") +AnnotationAssertion( "up-regulation of neurotransmitter secretion") +AnnotationAssertion( "upregulation of neurotransmitter secretion") +AnnotationAssertion( "activation of neurotransmitter secretion") +AnnotationAssertion( "stimulation of neurotransmitter secretion") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0001956") +AnnotationAssertion(rdfs:label "positive regulation of neurotransmitter secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + # Class: (intramembranous ossification) AnnotationAssertion(Annotation( "ISBN:0878932437") "Direct ossification that occurs within mesenchyme or an accumulation of relatively unspecialized cells.") @@ -27714,6 +46433,74 @@ AnnotationAssertion(rdfs:label "endo SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (regulation of cytokine-mediated signaling pathway) + +AnnotationAssertion(Annotation( "GOC:hjd") "Any process that modulates the frequency, rate or extent of the cytokine mediated signaling pathway.") +AnnotationAssertion( "regulation of cytokine and chemokine mediated signaling pathway") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "regulation of cytokine mediated signaling pathway") +AnnotationAssertion( "regulation of cytokine mediated signalling pathway") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0001959") +AnnotationAssertion(rdfs:label "regulation of cytokine-mediated signaling pathway") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (negative regulation of cytokine-mediated signaling pathway) + +AnnotationAssertion(Annotation( "GOC:hjd") "Any process that stops, prevents, or reduces the frequency, rate or extent of the cytokine mediated signaling pathway.") +AnnotationAssertion( "down regulation of cytokine mediated signaling pathway") +AnnotationAssertion( "down-regulation of cytokine mediated signaling pathway") +AnnotationAssertion( "downregulation of cytokine mediated signaling pathway") +AnnotationAssertion( "negative regulation of cytokine and chemokine mediated signaling pathway") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "negative regulation of cytokine mediated signaling pathway") +AnnotationAssertion( "negative regulation of cytokine mediated signalling pathway") +AnnotationAssertion( "inhibition of cytokine mediated signaling pathway") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0001960") +AnnotationAssertion(rdfs:label "negative regulation of cytokine-mediated signaling pathway") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (positive regulation of cytokine-mediated signaling pathway) + +AnnotationAssertion(Annotation( "GOC:hjd") "Any process that activates or increases the frequency, rate or extent of a cytokine mediated signaling pathway.") +AnnotationAssertion( "positive regulation of cytokine and chemokine mediated signaling pathway") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "positive regulation of cytokine mediated signaling pathway") +AnnotationAssertion( "positive regulation of cytokine mediated signalling pathway") +AnnotationAssertion( "up regulation of cytokine mediated signaling pathway") +AnnotationAssertion( "up-regulation of cytokine mediated signaling pathway") +AnnotationAssertion( "upregulation of cytokine mediated signaling pathway") +AnnotationAssertion( "activation of cytokine mediated signaling pathway") +AnnotationAssertion( "stimulation of cytokine mediated signaling pathway") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0001961") +AnnotationAssertion(rdfs:label "positive regulation of cytokine-mediated signaling pathway") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (synaptic transmission, dopaminergic) + +AnnotationAssertion(Annotation( "GOC:dos") Annotation( "GOC:dph") "The vesicular release of dopamine. from a presynapse, across a chemical synapse, the subsequent activation of dopamine receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.") +AnnotationAssertion( "dopaminergic synaptic transmission") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0001963") +AnnotationAssertion(rdfs:label "synaptic transmission, dopaminergic") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (G protein-coupled adenosine receptor signaling pathway) + +AnnotationAssertion(Annotation( "GOC:dph") "The series of molecular signals generated as a consequence of a receptor binding to extracellular adenosine and transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity.") +AnnotationAssertion(Annotation( "PMID:9755289") "P1 receptor signaling pathway") +AnnotationAssertion(Annotation( "PMID:9755289") "adenosine receptor signaling pathway, G-protein coupled") +AnnotationAssertion(Annotation( "GOC:mah") "adenosine receptor signalling pathway") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "adenosine receptor signaling pathway") +AnnotationAssertion( "GO:0001973") +AnnotationAssertion(rdfs:label "G protein-coupled adenosine receptor signaling pathway") +SubClassOf( ) + # Class: (nervous system process involved in regulation of systemic arterial blood pressure) AnnotationAssertion(Annotation( "GOC:mtg_cardio") Annotation( "ISBN:0721643949") "The regulation of blood pressure mediated by detection of stimuli and a neurological response.") @@ -27724,6 +46511,7 @@ AnnotationAssertion( "fast control of arterial pressure") AnnotationAssertion( "GO:0001976") AnnotationAssertion(rdfs:label "nervous system process involved in regulation of systemic arterial blood pressure") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (renal system process involved in regulation of blood volume) @@ -27772,6 +46560,19 @@ AnnotationAssertion(rdfs:label "regu SubClassOf( ) SubClassOf( ) +# Class: (regulation of systemic arterial blood pressure by circulatory renin-angiotensin) + +AnnotationAssertion(Annotation( "ISBN:0721643949") "The process in which angiotensinogen metabolites in the bloodstream modulate the force with which blood passes through the circulatory system. The process begins when renin is released and cleaves angiotensinogen.") +AnnotationAssertion( "circulatory renin-angiotensin blood pressure regulation") +AnnotationAssertion( "circulatory renin-angiotensin regulation of blood pressure") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "circulatory renin-angiotensin control of blood pressure") +AnnotationAssertion( "control of blood pressure by circulatory renin-angiotensin") +AnnotationAssertion( "renin-angiotensin blood pressure control") +AnnotationAssertion( "GO:0001991") +AnnotationAssertion(rdfs:label "regulation of systemic arterial blood pressure by circulatory renin-angiotensin") +SubClassOf( ) + # Class: (regulation of systemic arterial blood pressure by vasopressin) AnnotationAssertion(Annotation( "GOC:mtg_cardio") Annotation( "ISBN:0721643949") "The regulation of blood pressure mediated by the signaling molecule vasopressin. Vasopressin is produced in the hypothalamus, and affects vasoconstriction, and renal water transport.") @@ -27782,6 +46583,28 @@ AnnotationAssertion( "regulation of systemic arterial blood pressure by vasopressin") SubClassOf( ) +# Class: (renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure) + +AnnotationAssertion(Annotation( "GOC:dph") "The physiological response of the kidneys to a decrease in blood flow.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "renal response to blood flow during renin-angiotensin control of blood pressure") +AnnotationAssertion( "GO:0001999") +AnnotationAssertion(rdfs:label "renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (renin secretion into blood stream) + +AnnotationAssertion(Annotation( "ISBN:0721643949") "The regulated release of renin into the blood stream by juxtoglomerular cells.") +AnnotationAssertion( "renin release into blood stream") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002001") +AnnotationAssertion(rdfs:label "renin secretion into blood stream") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (detection of hypoxic conditions in blood by chemoreceptor signaling) AnnotationAssertion(Annotation( "GOC:dph") "The process in which information about a lack of oxygen are received and are converted to a molecular signal by chemoreceptors in the carotid bodies and the aortic bodies.") @@ -27801,9 +46624,19 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0002009") AnnotationAssertion(rdfs:label "morphogenesis of an epithelium") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (morphogenesis of an epithelial sheet) + +AnnotationAssertion(Annotation( "GOC:jl") "The process in which the anatomical structures of an epithelial sheet are generated and organized. An epithelial sheet is a flat surface consisting of closely packed epithelial cells.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002011") +AnnotationAssertion(rdfs:label "morphogenesis of an epithelial sheet") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + # Class: (regulation of blood volume by renin-angiotensin) AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_cardio") Annotation( "GOC:tb") Annotation( "ISBN:0721643949") "The process in which the renin-angiotensin system controls the rate of fluid intake and output into the blood.") @@ -27814,6 +46647,19 @@ AnnotationAssertion( "regulation of blood volume by renin-angiotensin") SubClassOf( ) +# Class: (renin-angiotensin regulation of aldosterone production) + +AnnotationAssertion(Annotation( "ISBN:0721643949") "The process in which an increase in active angiotensin stimulates the adrenal cortices to secrete aldosterone.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "renin-angiotensin control of aldosterone production") +AnnotationAssertion( "GO:0002018") +AnnotationAssertion(rdfs:label "renin-angiotensin regulation of aldosterone production") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (regulation of heart rate) AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") Annotation( "PMID:10358008") "Any process that modulates the frequency or rate of heart contraction.") @@ -27825,12 +46671,149 @@ AnnotationAssertion( "regulation of heart rate") SubClassOf( ) +# Class: (regulation of sodium ion transport) + +AnnotationAssertion(Annotation( "GOC:dph") "Any process that modulates the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion( "regulation of Na+ transport") +AnnotationAssertion( "regulation of sodium transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002028") +AnnotationAssertion(rdfs:label "regulation of sodium ion transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of L-glutamate import across plasma membrane) + +AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that modulates the frequency, rate or extent of L-glutamate import into a cell.") +AnnotationAssertion( "al") +AnnotationAssertion( "2012-06-13T07:34:08Z") +AnnotationAssertion( "GO:1900920") +AnnotationAssertion( "regulation of L-glutamate import") +AnnotationAssertion( "regulation of L-glutamate transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of L-glutamate uptake") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002036") +AnnotationAssertion(rdfs:label "regulation of L-glutamate import across plasma membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of L-glutamate import across plasma membrane) + +AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that stops, prevents or reduces the frequency, rate or extent of L-glutamate import into a cell.") +AnnotationAssertion( "al") +AnnotationAssertion( "2012-06-13T07:34:30Z") +AnnotationAssertion( "GO:1900921") +AnnotationAssertion( "down regulation of L-glutamate transport") +AnnotationAssertion( "down-regulation of L-glutamate transport") +AnnotationAssertion( "downregulation of L-glutamate transport") +AnnotationAssertion( "negative regulation of L-glutamate import") +AnnotationAssertion( "negative regulation of L-glutamate transport") +AnnotationAssertion( "regulation of L-glutamate import") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of L-glutamate import") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of L-glutamate import") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of L-glutamate import") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of L-glutamate import") +AnnotationAssertion( "inhibition of L-glutamate transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of L-glutamate uptake") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of L-glutamate uptake") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of L-glutamate uptake") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of L-glutamate uptake") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of L-glutamate uptake") +AnnotationAssertion( "GO:0002037") +AnnotationAssertion(rdfs:label "negative regulation of L-glutamate import across plasma membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of L-glutamate import across plasma membrane) + +AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that activates or increases the frequency, rate or extent of L-glutamate import into a cell.") +AnnotationAssertion( "al") +AnnotationAssertion( "2012-06-13T07:34:38Z") +AnnotationAssertion( "GO:1900922") +AnnotationAssertion( "positive regulation of L-glutamate import") +AnnotationAssertion( "positive regulation of L-glutamate transport") +AnnotationAssertion( "up regulation of L-glutamate transport") +AnnotationAssertion( "upregulation of L-glutamate transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of L-glutamate import") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of L-glutamate import") +AnnotationAssertion( "up-regulation of L-glutamate transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of L-glutamate import") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of L-glutamate import") +AnnotationAssertion( "activation of L-glutamate transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of L-glutamate uptake") +AnnotationAssertion( "stimulation of L-glutamate transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of L-glutamate uptake") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of L-glutamate uptake") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of L-glutamate uptake") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of L-glutamate uptake") +AnnotationAssertion( "GO:0002038") +AnnotationAssertion(rdfs:label "positive regulation of L-glutamate import across plasma membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of neuroblast proliferation) + +AnnotationAssertion(Annotation( "GOC:dph") "Any process that activates or increases the rate of neuroblast proliferation.") +AnnotationAssertion( "up regulation of neuroblast proliferation") +AnnotationAssertion( "up-regulation of neuroblast proliferation") +AnnotationAssertion( "upregulation of neuroblast proliferation") +AnnotationAssertion( "activation of neuroblast proliferation") +AnnotationAssertion( "stimulation of neuroblast proliferation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002052") +AnnotationAssertion(rdfs:label "positive regulation of neuroblast proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (positive regulation of mesenchymal cell proliferation) + +AnnotationAssertion(Annotation( "GOC:dph") "The process of activating or increasing the rate or extent of mesenchymal cell proliferation. Mesenchymal cells are loosely organized embryonic cells.") +AnnotationAssertion( "up regulation of mesenchymal cell proliferation") +AnnotationAssertion( "up-regulation of mesenchymal cell proliferation") +AnnotationAssertion( "upregulation of mesenchymal cell proliferation") +AnnotationAssertion( "activation of mesenchymal cell proliferation") +AnnotationAssertion( "stimulation of mesenchymal cell proliferation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002053") +AnnotationAssertion(rdfs:label "positive regulation of mesenchymal cell proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (nucleobase binding) + +AnnotationAssertion(Annotation( "GOC:hjd") "Binding to a nucleobase, any of a class of pyrmidines or purines, organic nitrogenous bases.") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0002054") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "nucleobase binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (adenine binding) + +AnnotationAssertion(Annotation( "GOC:hjd") "Binding to adenine, a purine base.") +AnnotationAssertion( "6-aminopurine binding") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0002055") +AnnotationAssertion(rdfs:label "adenine binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (purine nucleobase binding) + +AnnotationAssertion(Annotation( "GOC:hjd") "Binding to a purine nucleobase, an organic nitrogenous base with a purine skeleton.") +AnnotationAssertion(Annotation( "GOC:go_curators") "purine base binding") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "purine binding") +AnnotationAssertion( "GO:0002060") +AnnotationAssertion(rdfs:label "purine nucleobase binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (chondrocyte differentiation) AnnotationAssertion(Annotation( "GOC:dph") "The process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte. A chondrocyte is a polymorphic cell that forms cartilage.") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0002062") AnnotationAssertion(rdfs:label "chondrocyte differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) @@ -27840,9 +46823,201 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:0002063") AnnotationAssertion(rdfs:label "chondrocyte development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (epithelial cell development) + +AnnotationAssertion(Annotation( "GOC:dph") "The process whose specific outcome is the progression of an epithelial cell over time, from its formation to the mature structure. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002064") +AnnotationAssertion(rdfs:label "epithelial cell development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (columnar/cuboidal epithelial cell differentiation) + +AnnotationAssertion(Annotation( "GOC:dph") "The process in which a relatively unspecialized cell acquires specialized features of a columnar/cuboidal epithelial cell. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002065") +AnnotationAssertion(rdfs:label "columnar/cuboidal epithelial cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (columnar/cuboidal epithelial cell development) + +AnnotationAssertion(Annotation( "GOC:dph") "The process whose specific outcome is the progression of a columnar/cuboidal epithelial cell over time, from its formation to the mature structure. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002066") +AnnotationAssertion(rdfs:label "columnar/cuboidal epithelial cell development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (glandular epithelial cell differentiation) + +AnnotationAssertion(Annotation( "GOC:dph") "The process in which a relatively unspecialized cell acquires specialized features of a glandular epithelial cell. A glandular epithelial cell is a columnar/cuboidal epithelial cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002067") +AnnotationAssertion(rdfs:label "glandular epithelial cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (glandular epithelial cell development) + +AnnotationAssertion(Annotation( "GOC:dph") "The process whose specific outcome is the progression of a glandular epithelial cell over time, from its formation to the mature structure. A glandular epithelial cell is a columnar/cuboidal epithelial cell is a cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002068") +AnnotationAssertion(rdfs:label "glandular epithelial cell development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (columnar/cuboidal epithelial cell maturation) + +AnnotationAssertion(Annotation( "GOC:dph") "The developmental process, independent of morphogenetic (shape) change, that is required for a columna/cuboidal epithelial cell to attain its fully functional state. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002069") +AnnotationAssertion(rdfs:label "columnar/cuboidal epithelial cell maturation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (epithelial cell maturation) + +AnnotationAssertion(Annotation( "GOC:dph") "The developmental process, independent of morphogenetic (shape) change, that is required for an epithelial cell to attain its fully functional state. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002070") +AnnotationAssertion(rdfs:label "epithelial cell maturation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (glandular epithelial cell maturation) + +AnnotationAssertion(Annotation( "GOC:dph") "The developmental process, independent of morphogenetic (shape) change, that is required for a glandular epithelial cell to attain its fully functional state. A glandular epithelial cell is a columnar/cuboidal epithelial cell is a cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002071") +AnnotationAssertion(rdfs:label "glandular epithelial cell maturation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (optic cup morphogenesis involved in camera-type eye development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_sensu") Annotation( "GOC:sdb_2009") Annotation( "GOC:tb") Annotation( "ISBN:0878932437") "The invagination of the optic vesicle to form two-walled indentations, the optic cups, that will go on to form the retina. This process begins with the optic vesicle becoming a two-walled structure and its subsequent shape changes. It does not include the fate commitment of cells to become the pigmented retina and the neural retina. An example of this process is found in Mus musculus.") +AnnotationAssertion( "optic cup morphogenesis involved in camera-style eye development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002072") +AnnotationAssertion(rdfs:label "optic cup morphogenesis involved in camera-type eye development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (extraocular skeletal muscle development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_muscle") Annotation( "GOC:mtg_sensu") Annotation( "MA:0001271") Annotation( "PMID:16638982") "The process whose specific outcome is the progression of the extraocular skeletal muscle over time, from its formation to the mature structure. The extraocular muscle is derived from cranial mesoderm and controls eye movements. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle. An example of this process is found in Mus musculus.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002074") +AnnotationAssertion(rdfs:label "extraocular skeletal muscle development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (somitomeric trunk muscle development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:16638982") "The process whose specific outcome is the progression of the somitomeric trunk muscle over time, from its formation to the mature structure. The somitomeric trunk muscle is derived from somitomeric mesoderm. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle. An example of this process is found in Mus musculus.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002075") +AnnotationAssertion(rdfs:label "somitomeric trunk muscle development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (osteoblast development) + +AnnotationAssertion(Annotation( "GOC:dph") "The process whose specific outcome is the progression of an osteoblast over time, from its formation to the mature structure. Osteoblast development does not include the steps involved in committing a cranial neural crest cell or an osteoprogenitor cell to an osteoblast fate. An osteoblast is a cell that gives rise to bone.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002076") +AnnotationAssertion(rdfs:label "osteoblast development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (acrosomal membrane) + +AnnotationAssertion(Annotation( "GOC:dph") "The membrane that surrounds the acrosomal lumen. The acrosome is a special type of lysosome in the head of a spermatozoon that contains acid hydrolases and is concerned with the breakdown of the outer membrane of the ovum during fertilization.") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0002080") +AnnotationAssertion(rdfs:label "acrosomal membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (inhibition of neuroepithelial cell differentiation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:16678814") "Any process that prevents the activation of neuroepithelial cell differentiation. Neuroepithelial cell differentiation is the process in which epiblast cells acquire specialized features of neuroepithelial cells.") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "negative regulation of neural plate formation") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "repression of premature neural plate formation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002085") +AnnotationAssertion(rdfs:label "inhibition of neuroepithelial cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of respiratory gaseous exchange by nervous system process) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") Annotation( "PMID:12458206") "A process carried out by the nervous system that is required for the proper control of respiratory gaseous exchange. This process occurs in the respiratory center of the brain in vertebrates.") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "neurological control of breathing") +AnnotationAssertion( "regulation of respiratory gaseous exchange by neurological system process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002087") +AnnotationAssertion(rdfs:label "regulation of respiratory gaseous exchange by nervous system process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (lens development in camera-type eye) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "ISBN:0582064333") "The process whose specific outcome is the progression of the lens over time, from its formation to the mature structure. The lens is a transparent structure in the eye through which light is focused onto the retina. An example of this process is found in Mus musculus.") +AnnotationAssertion( "lens development") +AnnotationAssertion( "lens development in camera-style eye") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002088") +AnnotationAssertion(rdfs:label "lens development in camera-type eye") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (lens morphogenesis in camera-type eye) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_sensu") "The process in which the anatomical structures of the lens are generated and organized. The lens is a transparent structure in the eye through which light is focused onto the retina. An example of this process is found in Mus musculus.") +AnnotationAssertion( "lens morphogenesis") +AnnotationAssertion( "lens morphogenesis in camera-style eye") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002089") +AnnotationAssertion(rdfs:label "lens morphogenesis in camera-type eye") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (auditory receptor cell morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that alters the size or shape of an auditory receptor cell.") +AnnotationAssertion(Annotation( "GO:dph") "hair cell morphogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002093") +AnnotationAssertion(rdfs:label "auditory receptor cell morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (amphibian larval development) AnnotationAssertion(Annotation( "GOC:bf") Annotation( "PMID:27143402") "The process whose specific outcome is the progression of the amphibian larva over time, from its formation to the mature structure. Amphibian larvae, sometimes called pollywogs or tadpoles, hatch from eggs and begin to grow limbs and other adult physical features at various times, depending on the species, before they metamorphose into the adult form.") @@ -27857,10 +47032,22 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:0002119") AnnotationAssertion(rdfs:label "nematode larval development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectAllValuesFrom( )) +# Class: (osteoclast proliferation) + +AnnotationAssertion(Annotation( "CL:0000092") Annotation( "GOC:hjd") "The multiplication or reproduction of osteoclasts, resulting in the expansion of an osteoclast cell population. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue, which typically differentiates from monocytes.") +AnnotationAssertion( "hjd") +AnnotationAssertion( "2010-02-03T01:50:37Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002158") +AnnotationAssertion(rdfs:label "osteoclast proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + # Class: (larval development) AnnotationAssertion(Annotation( "GOC:jid") Annotation( "ISBN:0877795088") "The process whose specific outcome is the progression of the larva over time, from its formation to the mature structure. The larva is the early, immature form of an that at birth or hatching is fundamentally unlike its parent and must metamorphose before assuming the adult characters.") @@ -27890,6 +47077,192 @@ AnnotationAssertion(rdfs:label "inst SubClassOf( ) SubClassOf( ) +# Class: (male germ cell proliferation) + +AnnotationAssertion(Annotation( "GOC:hjd") "The multiplication or reproduction of male germ cells, resulting in the expansion of a cell population.") +AnnotationAssertion( "hjd") +AnnotationAssertion( "2010-11-18T02:35:14Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002176") +AnnotationAssertion(rdfs:label "male germ cell proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (cytoplasmic translation) + +AnnotationAssertion(Annotation( "GOC:hjd") "The chemical reactions and pathways resulting in the formation of a protein in the cytoplasm. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein.") +AnnotationAssertion( "hjd") +AnnotationAssertion( "2011-06-09T03:11:53Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002181") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:comment "Note that this term applies to translation performed by cytoplasmic ribosomes, which is distinct from translation performed by organellar ribosomes. For mitochondrial translation, consider GO:0032543 'mitochondrial translation' or its child terms.") +AnnotationAssertion(rdfs:label "cytoplasmic translation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (cytoplasmic translational elongation) + +AnnotationAssertion(Annotation( "GOC:hjd") "The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis in the cytoplasm.") +AnnotationAssertion( "hjd") +AnnotationAssertion( "2011-06-09T03:14:42Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002182") +AnnotationAssertion(rdfs:label "cytoplasmic translational elongation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (cytoplasmic translational initiation) + +AnnotationAssertion(Annotation( "GOC:hjd") "The process preceding formation of the peptide bond between the first two amino acids of a protein in the cytoplasm. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA.") +AnnotationAssertion( "hjd") +AnnotationAssertion( "2011-06-09T03:15:48Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002183") +AnnotationAssertion(rdfs:label "cytoplasmic translational initiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (cytoplasmic translational termination) + +AnnotationAssertion(Annotation( "GOC:hjd") "The process resulting in the release of a polypeptide chain from the ribosome in the cytoplasm, usually in response to a termination codon.") +AnnotationAssertion( "hjd") +AnnotationAssertion( "2011-06-09T03:17:13Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002184") +AnnotationAssertion(rdfs:label "cytoplasmic translational termination") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (somatic diversification of immune receptors) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") Annotation( "PMID:16102575") Annotation( "PMID:16166509") "The somatic process allowing for the production of immune receptors whose specificity is not encoded in the germline genomic sequences.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002200") +AnnotationAssertion(rdfs:comment "Note that this process covers somatic recombination, gene conversion, hypermutation, N-region addition, and alternate splicing processes of immune receptor diversification.") +AnnotationAssertion(rdfs:label "somatic diversification of immune receptors") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (somatic recombination of immunoglobulin genes involved in immune response) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") "The process in which immunoglobulin genes are formed through recombination of the germline genetic elements, also known as immunoglobulin gene segments, within a single locus following the induction of and contributing to an immune response.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "somatic recombination of antibody genes during immune response") +AnnotationAssertion(Annotation( "GOC:dph") "somatic recombination of immunoglobulin genes during immune response") +AnnotationAssertion( "GO:0002204") +AnnotationAssertion(rdfs:label "somatic recombination of immunoglobulin genes involved in immune response") +SubClassOf( ) +SubClassOf( ) + +# Class: (somatic diversification of immunoglobulins involved in immune response) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") Annotation( "PMID:14991701") "The somatic process that results in the generation of sequence diversity of immunoglobulins after induction, and contributes to an immune response.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "somatic diversification of antibodies during immune response") +AnnotationAssertion(Annotation( "GOC:dph") "somatic diversification of immunoglobulins during immune response") +AnnotationAssertion( "GO:0002208") +AnnotationAssertion(rdfs:label "somatic diversification of immunoglobulins involved in immune response") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (defense response to insect) + +AnnotationAssertion(Annotation( "GOC:add") "A response to protect an organism from a directly detected or perceived external threat from an insect or insects to that organism.") +AnnotationAssertion( "GO:0002214") +AnnotationAssertion( "physiological defense response to insect") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002213") +AnnotationAssertion(rdfs:label "defense response to insect") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (defense response to nematode) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "PMID:11516579") Annotation( "PMID:14506883") "A response to protect an organism from a directly detected or perceived external threat from a nematode or nematodes, which results in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.") +AnnotationAssertion( "GO:0002216") +AnnotationAssertion( "physiological defense response to nematode") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002215") +AnnotationAssertion(rdfs:label "defense response to nematode") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of antimicrobial peptide production) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "PMID:11807545") "Any process that activates or increases the frequency, rate, or extent of antimicrobial peptide production.") +AnnotationAssertion( "antimicrobial peptide induction") +AnnotationAssertion( "up regulation of antimicrobial peptide production") +AnnotationAssertion( "up-regulation of antimicrobial peptide production") +AnnotationAssertion( "upregulation of antimicrobial peptide production") +AnnotationAssertion( "activation of antimicrobial peptide production") +AnnotationAssertion( "stimulation of antimicrobial peptide production") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002225") +AnnotationAssertion(rdfs:label "positive regulation of antimicrobial peptide production") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (leukocyte chemotaxis involved in inflammatory response) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") "The movement of an immune cell in response to an external stimulus contributing to an inflammatory response.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "immune cell chemotaxis during inflammatory response") +AnnotationAssertion( "leucocyte chemotaxis during inflammatory response") +AnnotationAssertion(Annotation( "GOC:dph") "leukocyte chemotaxis during inflammatory response") +AnnotationAssertion( "GO:0002232") +AnnotationAssertion(rdfs:label "leukocyte chemotaxis involved in inflammatory response") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (leukocyte chemotaxis involved in immune response) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") "The movement of an immune cell in response to an external stimulus a part of an immune response.") +AnnotationAssertion( "immune cell chemotaxis during immune response") +AnnotationAssertion( "leucocyte chemotaxis during immune response") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002233") +AnnotationAssertion(rdfs:label "leukocyte chemotaxis involved in immune response") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (hematopoietic progenitor cell differentiation) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:rl") Annotation( "ISBN:0781735149") Annotation( "PMID:16551251") "The process in which precursor cell type acquires the specialized features of a hematopoietic progenitor cell, a class of cell types including myeloid progenitor cells and lymphoid progenitor cells.") +AnnotationAssertion( "haematopoietic progenitor cell differentiation") +AnnotationAssertion( "haemopoietic progenitor cell differentiation") +AnnotationAssertion( "hemopoietic progenitor cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002244") +AnnotationAssertion(rdfs:label "hematopoietic progenitor cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (wound healing involved in inflammatory response) + +AnnotationAssertion(Annotation( "GOC:jal") Annotation( "ISBN:0721601871") "The series of events that restore integrity to damaged tissue that contribute to an inflammatory response.") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") "healing during inflammatory response") +AnnotationAssertion(Annotation( "GOC:dph") "inflammatory response wound healing") +AnnotationAssertion( "GO:0002246") +AnnotationAssertion(rdfs:label "wound healing involved in inflammatory response") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (adaptive immune response) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "GO_REF:0000022") Annotation( "ISBN:0781735149") "An immune response mediated by cells expressing specific receptors for antigens produced through a somatic diversification process, and allowing for an enhanced secondary response to subsequent exposures to the same antigen (immunological memory).") +AnnotationAssertion( "Wikipedia:Adaptive_immune_system") +AnnotationAssertion(Annotation( "ISBN:068340007X") "acquired immune response") +AnnotationAssertion(Annotation( "GOC:add") "immune memory response") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002250") +AnnotationAssertion(rdfs:label "adaptive immune response") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectAllValuesFrom( )) + # Class: (organ or tissue specific immune response) AnnotationAssertion(Annotation( "GOC:jal") Annotation( "GO_REF:0000022") "An immune response taking place in an organ or tissues such as the liver, brain, mucosa, or nervous system tissues.") @@ -27908,6 +47281,25 @@ AnnotationAssertion( "immune effector process") SubClassOf( ) +# Class: (lymphocyte homeostasis) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "PMID:15826826") Annotation( "PMID:16319493") Annotation( "PMID:16551252") Annotation( "PMID:16551262") "The process of regulating the proliferation and elimination of lymphocytes such that the total number of lymphocytes within a whole or part of an organism is stable over time in the absence of an outside stimulus.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002260") +AnnotationAssertion(rdfs:label "lymphocyte homeostasis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (myeloid cell homeostasis) + +AnnotationAssertion(Annotation( "CL:0000763") Annotation( "GOC:add") "The process of regulating the proliferation and elimination of myeloid cells such that the total number of myeloid cells within a whole or part of an organism is stable over time in the absence of an outside stimulus.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002262") +AnnotationAssertion(rdfs:label "myeloid cell homeostasis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + # Class: (cell activation involved in immune response) AnnotationAssertion(Annotation( "GOC:add") Annotation( "GO_REF:0000022") Annotation( "ISBN:0781735149") "A change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response.") @@ -27916,7 +47308,6 @@ AnnotationAssertion(Annotation( "GO:0002263") AnnotationAssertion(rdfs:label "cell activation involved in immune response") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) SubClassOf( ) # Class: (endothelial cell activation involved in immune response) @@ -27997,7 +47388,7 @@ AnnotationAssertion(Annotation( "GO:0002281") AnnotationAssertion(rdfs:label "macrophage activation involved in immune response") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) # Class: (neutrophil activation involved in immune response) @@ -28025,9 +47416,52 @@ AnnotationAssertion( "GOC:tb") "lymphocyte activation during immune response") AnnotationAssertion( "GO:0002285") AnnotationAssertion(rdfs:label "lymphocyte activation involved in immune response") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) +# Class: (T cell activation involved in immune response) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") "The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific, leading to the initiation or perpetuation of an immune response.") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:tb") "T cell activation during immune response") +AnnotationAssertion( "T lymphocyte activation during immune response") +AnnotationAssertion( "T-cell activation during immune response") +AnnotationAssertion( "T-lymphocyte activation during immune response") +AnnotationAssertion( "GO:0002286") +AnnotationAssertion(rdfs:label "T cell activation involved in immune response") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (T cell differentiation involved in immune response) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") "The process in which an antigenically naive T cell acquires the specialized features of an effector, regulatory, or memory T cell as part of an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells.") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:add") "T cell development involved in immune response") +AnnotationAssertion(Annotation( "GOC:tb") "T cell differentiation during immune response") +AnnotationAssertion( "T lymphocyte differentiation during immune response") +AnnotationAssertion( "T-cell differentiation during immune response") +AnnotationAssertion( "T-lymphocyte differentiation during immune response") +AnnotationAssertion( "GO:0002292") +AnnotationAssertion(rdfs:comment "Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.") +AnnotationAssertion(rdfs:label "T cell differentiation involved in immune response") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (T cell proliferation involved in immune response) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") "The expansion of a T cell population by cell division as part of an immune response.") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:tb") "T cell proliferation during immune response") +AnnotationAssertion( "T lymphocyte proliferation during immune response") +AnnotationAssertion( "T-cell proliferation during immune response") +AnnotationAssertion( "T-lymphocyte proliferation during immune response") +AnnotationAssertion( "GO:0002309") +AnnotationAssertion(rdfs:label "T cell proliferation involved in immune response") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (B cell activation involved in immune response) AnnotationAssertion(Annotation( "GOC:jal") "The change in morphology and behavior of a mature or immature B cell during an immune response, resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.") @@ -28038,6 +47472,7 @@ AnnotationAssertion( "B-lymphocyte activation during immune response") AnnotationAssertion( "GO:0002312") AnnotationAssertion(rdfs:label "B cell activation involved in immune response") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) @@ -28053,9 +47488,52 @@ AnnotationAssertion( "GO:0002313") AnnotationAssertion(rdfs:comment "Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.") AnnotationAssertion(rdfs:label "mature B cell differentiation involved in immune response") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) +# Class: (germinal center B cell differentiation) + +AnnotationAssertion(Annotation( "GOC:jal") Annotation( "ISBN:0781735149") "The process in which a B cell in the spleen acquires the specialized features of a germinal center B cell. Germinal center B cells are rapidly cycling B cells which have downregulated IgD expression and exhibit high levels of binding by peanut agglutinin (PNA).") +AnnotationAssertion( "germinal center B lymphocyte differentiation") +AnnotationAssertion( "germinal center B-cell differentiation") +AnnotationAssertion( "germinal center B-lymphocyte differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:add") "germinal center B cell development") +AnnotationAssertion( "GO:0002314") +AnnotationAssertion(rdfs:comment "Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.") +AnnotationAssertion(rdfs:label "germinal center B cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (marginal zone B cell differentiation) + +AnnotationAssertion(Annotation( "GOC:jal") Annotation( "ISBN:0781735149") "The process in which a B cell in the spleen acquires the specialized features of a marginal zone B cell. Marginal zone B cells are localized in a distinct anatomical region of the spleen that represents the major antigen-filtering and scavenging area (by specialized macrophages resident there). It appears that they are preselected to express a BCR repertoire similar to B-1 B cells, biased toward bacterial cell wall constituents and senescent self-components (such as oxidized LDL).") +AnnotationAssertion( "marginal zone B lymphocyte differentiation") +AnnotationAssertion( "marginal zone B-cell differentiation") +AnnotationAssertion( "marginal zone B-lymphocyte differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:add") "marginal zone B cell development") +AnnotationAssertion( "GO:0002315") +AnnotationAssertion(rdfs:comment "Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.") +AnnotationAssertion(rdfs:label "marginal zone B cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (follicular B cell differentiation) + +AnnotationAssertion(Annotation( "GOC:jal") Annotation( "ISBN:0781735149") "The process in which a B cell in the spleen acquires the specialized features of a follicular B cell. Follicular B cells are major population of mature recirculating B cells in the spleen and are located in the B-cell follicle region.") +AnnotationAssertion( "follicular B lymphocyte differentiation") +AnnotationAssertion( "follicular B-cell differentiation") +AnnotationAssertion( "follicular B-lymphocyte differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:add") "follicular B cell development") +AnnotationAssertion( "GO:0002316") +AnnotationAssertion(rdfs:comment "Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.") +AnnotationAssertion(rdfs:label "follicular B cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + # Class: (plasma cell differentiation) AnnotationAssertion(Annotation( "GOC:jal") "The process in which a B cell acquires the specialized features of a plasma cell. A plasma cell is a lymphocyte which develops from a B cell and produces high amounts of antibody.") @@ -28064,8 +47542,18 @@ AnnotationAssertion(Annotation( "GO:0002317") AnnotationAssertion(rdfs:comment "Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.") AnnotationAssertion(rdfs:label "plasma cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (myeloid progenitor cell differentiation) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "PMID:16551264") "The process in which a precursor cell type acquires the specialized features of a myeloid progenitor cell. Myeloid progenitor cells include progenitor cells for any of the myeloid lineages.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002318") +AnnotationAssertion(rdfs:label "myeloid progenitor cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + # Class: (memory B cell differentiation) AnnotationAssertion(Annotation( "GOC:jal") Annotation( "ISBN:0781735149") "The process in which a B cell acquires the specialized features of a memory B cell. Memory B cells are cells that can respond rapidly to antigen re-exposure by production of high-affinity antibody.") @@ -28077,9 +47565,84 @@ AnnotationAssertion(Annotation( "GO:0002319") AnnotationAssertion(rdfs:comment "Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.") AnnotationAssertion(rdfs:label "memory B cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) +# Class: (lymphoid progenitor cell differentiation) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "PMID:16551251") Annotation( "PMID:16551264") "The process in which a precursor cell type acquires the specialized features of a lymphoid progenitor cell. Lymphoid progenitor cells include progenitor cells for any of the lymphoid lineages.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002320") +AnnotationAssertion(rdfs:label "lymphoid progenitor cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (B cell proliferation involved in immune response) + +AnnotationAssertion(Annotation( "GOC:jal") "The expansion of a B cell population by cell division following B cell activation during an immune response.") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:tb") "B cell proliferation during immune response") +AnnotationAssertion( "B lymphocyte proliferation during immune response") +AnnotationAssertion( "B-cell proliferation during immune response") +AnnotationAssertion( "B-lymphocyte proliferation during immune response") +AnnotationAssertion( "GO:0002322") +AnnotationAssertion(rdfs:label "B cell proliferation involved in immune response") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (immature B cell differentiation) + +AnnotationAssertion(Annotation( "GOC:jal") Annotation( "ISBN:0781735149") Annotation( "PMID:16551251") "The process in which a precursor cell type acquires the specialized features of an immature B cell.") +AnnotationAssertion( "immature B lymphocyte differentiation") +AnnotationAssertion( "immature B-cell differentiation") +AnnotationAssertion( "immature B-lymphocyte differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:add") "immature B cell development") +AnnotationAssertion( "GO:0002327") +AnnotationAssertion(rdfs:comment "Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.") +AnnotationAssertion(rdfs:label "immature B cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (pro-B cell differentiation) + +AnnotationAssertion(Annotation( "GOC:jal") Annotation( "ISBN:0781735149") "The process in which a precursor cell type acquires the specialized features of a pro-B cell. Pro-B cells are the earliest stage of the B cell lineage and undergo heavy chain D and J gene rearrangements, although they are not fully committed.") +AnnotationAssertion( "pro-B lymphocyte differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:add") "pro-B cell development") +AnnotationAssertion( "GO:0002328") +AnnotationAssertion(rdfs:label "pro-B cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (pre-B cell differentiation) + +AnnotationAssertion(Annotation( "GOC:jal") Annotation( "ISBN:0781735149") "The process in which a precursor cell type acquires the specialized features of a pre-B cell. Pre-B cells follow the pro-B cell stage of immature B cell differentiation and undergo rearrangement of heavy chain V, D, and J gene segments.") +AnnotationAssertion( "pre-B lymphocyte differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:add") "pre-B cell development") +AnnotationAssertion( "GO:0002329") +AnnotationAssertion(rdfs:comment "Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.") +AnnotationAssertion(rdfs:label "pre-B cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (transitional stage B cell differentiation) + +AnnotationAssertion(Annotation( "GOC:jal") Annotation( "ISBN:0781735149") "The process in which immature B cells from the bone marrow become mature B cells in the spleen. Transitional stage B cells are subdivided into transitional one (T1) and transitional two (T2) stages and are short-lived and functionally incompetent.") +AnnotationAssertion( "transitional stage B lymphocyte differentiation") +AnnotationAssertion( "transitional stage B-cell differentiation") +AnnotationAssertion( "transitional stage B-lymphocyte differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:add") "transitional stage B cell development") +AnnotationAssertion( "GO:0002332") +AnnotationAssertion(rdfs:comment "Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.") +AnnotationAssertion(rdfs:label "transitional stage B cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + # Class: (mature B cell differentiation) AnnotationAssertion(Annotation( "GOC:jal") Annotation( "ISBN:0781735149") "The process in which transitional stage B cells acquire the specialized features of mature B cells in the spleen.") @@ -28091,8 +47654,75 @@ AnnotationAssertion(Annotation( "GO:0002335") AnnotationAssertion(rdfs:comment "Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.") AnnotationAssertion(rdfs:label "mature B cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (B cell selection) + +AnnotationAssertion(Annotation( "GOC:jal") "The process dependent upon B cell antigen receptor signaling in response to self or foreign antigen through which B cells are selected for survival.") +AnnotationAssertion( "B lymphocyte selection") +AnnotationAssertion( "B-cell selection") +AnnotationAssertion( "B-lymphocyte selection") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002339") +AnnotationAssertion(rdfs:label "B cell selection") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (peripheral B cell selection) + +AnnotationAssertion(Annotation( "GOC:jal") "Any B cell selection process that occurs in the periphery.") +AnnotationAssertion( "peripheral B lymphocyte selection") +AnnotationAssertion( "peripheral B-cell selection") +AnnotationAssertion( "peripheral B-lymphocyte selection") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002343") +AnnotationAssertion(rdfs:label "peripheral B cell selection") +SubClassOf( ) + +# Class: (B cell affinity maturation) + +AnnotationAssertion(Annotation( "GOC:jal") Annotation( "GO_REF:0000022") Annotation( "ISBN:0781735149") "The process in which B cells produce antibodies with increased antigen affinity. This is accomplished by somatic hypermutation and selection for B cells which produce higher affinity antibodies to antigen.") +AnnotationAssertion( "B lymphocyte affinity maturation") +AnnotationAssertion( "B-cell affinity maturation") +AnnotationAssertion( "B-lymphocyte affinity maturation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002344") +AnnotationAssertion(rdfs:label "B cell affinity maturation") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (histamine production involved in inflammatory response) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") Annotation( "PMID:16730260") "The synthesis or release of histamine following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels.") +AnnotationAssertion( "histamine production involved in acute inflammatory response") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002349") +AnnotationAssertion(rdfs:label "histamine production involved in inflammatory response") +SubClassOf( ) + +# Class: (serotonin production involved in inflammatory response) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") Annotation( "PMID:16730260") "The synthesis or release of serotonin following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels.") +AnnotationAssertion( "serotonin production involved in acute inflammatory response") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002351") +AnnotationAssertion(rdfs:label "serotonin production involved in inflammatory response") +SubClassOf( ) + +# Class: (B cell homeostatic proliferation) + +AnnotationAssertion(Annotation( "GOC:jal") "The non-specific expansion of B cell populations within a whole or part of an organism to reach to a total number of B cells which will then remain stable over time in the absence of an external stimulus.") +AnnotationAssertion( "B lymphocyte homeostatic proliferation") +AnnotationAssertion( "B-cell homeostatic proliferation") +AnnotationAssertion( "B-lymphocyte homeostatic proliferation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002358") +AnnotationAssertion(rdfs:label "B cell homeostatic proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf( ) + # Class: (leukocyte activation involved in immune response) AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") "A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.") @@ -28102,8 +47732,8 @@ AnnotationAssertion( "GOC:tb") "leukocyte activation during immune response") AnnotationAssertion( "GO:0002366") AnnotationAssertion(rdfs:label "leukocyte activation involved in immune response") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -SubClassOf( ) # Class: (cytokine production involved in immune response) @@ -28211,16 +47841,110 @@ AnnotationAssertion(rdfs:comment "No AnnotationAssertion(rdfs:label "immunoglobulin production") SubClassOf( ) +# Class: (immunoglobulin production involved in immunoglobulin-mediated immune response) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") Annotation( "PMID:9185563") "The appearance of immunoglobulin due to biosynthesis or secretion following a cellular stimulus during an immune response, resulting in an increase in its intracellular or extracellular levels.") +AnnotationAssertion( "GO:0002379") +AnnotationAssertion( "GO:0002380") +AnnotationAssertion( "immunoglobulin production involved in immunoglobulin mediated immune response") +AnnotationAssertion( "immunoglobulin biosynthetic process involved in immune response") +AnnotationAssertion( "immunoglobulin secretion involved in immune response") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "antibody production during immune response") +AnnotationAssertion( "antibody secretion during immune response") +AnnotationAssertion(Annotation( "GOC:dph") "immunoglobulin production during immune response") +AnnotationAssertion(Annotation( "GOC:dph") "immunoglobulin production involved in immune response") +AnnotationAssertion( "GO:0002381") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.") +AnnotationAssertion(rdfs:label "immunoglobulin production involved in immunoglobulin-mediated immune response") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (hepatic immune response) AnnotationAssertion(Annotation( "GOC:jal") Annotation( "GO_REF:0000022") Annotation( "ISBN:0781735149") "An immune response taking place in the liver.") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0002384") AnnotationAssertion(rdfs:label "hepatic immune response") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectAllValuesFrom( )) +# Class: (immune response in gut-associated lymphoid tissue) + +AnnotationAssertion(Annotation( "GOC:jal") Annotation( "ISBN:0781735149") "Immune response taking place in the gut-associated lymphoid tissue (GALT). GALT includes Peyer's patches, appendix, and solitary lymph nodules.") +AnnotationAssertion( "immune response in GALT") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002387") +AnnotationAssertion(rdfs:label "immune response in gut-associated lymphoid tissue") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (immune response in Peyer's patch) + +AnnotationAssertion(Annotation( "GOC:jal") Annotation( "ISBN:0781735149") "Immune response taking place in the Peyer's patch, nodular lymphoid structures on the serosal surface of the small intestine.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002388") +AnnotationAssertion(rdfs:label "immune response in Peyer's patch") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectAllValuesFrom( )) + +# Class: (immune response in nasopharyngeal-associated lymphoid tissue) + +AnnotationAssertion(Annotation( "GOC:jal") Annotation( "ISBN:0781735149") "An immune response taking place in the nasopharyngeal-associated lymphoid tissue (NALT). NALT includes the tonsils and adenoids.") +AnnotationAssertion( "immune response in NALT") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002395") +AnnotationAssertion(rdfs:label "immune response in nasopharyngeal-associated lymphoid tissue") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (MHC protein complex assembly) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") Annotation( "PMID:15771591") Annotation( "PMID:15928678") "The aggregation, arrangement and bonding together of a set of components to form an MHC protein complex.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002396") +AnnotationAssertion(rdfs:label "MHC protein complex assembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (MHC class II protein complex assembly) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") Annotation( "PMID:15771591") "The aggregation, arrangement and bonding together of a set of components to form an MHC class II protein complex.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002399") +AnnotationAssertion(rdfs:label "MHC class II protein complex assembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (dendritic cell chemotaxis) + +AnnotationAssertion(Annotation( "CL:0000451") Annotation( "GOC:add") Annotation( "ISBN:0781735149") Annotation( "PMID:15814331") Annotation( "PMID:16056255") "The movement of a dendritic cell in response to an external stimulus.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002407") +AnnotationAssertion(rdfs:label "dendritic cell chemotaxis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (myeloid dendritic cell chemotaxis) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") Annotation( "PMID:15814331") Annotation( "PMID:16056255") "The movement of a myeloid dendritic cell in response to an external stimulus.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002408") +AnnotationAssertion(rdfs:label "myeloid dendritic cell chemotaxis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (Langerhans cell chemotaxis) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "PMID:16056255") Annotation( "PMID:16387601") "The movement of a Langerhans cell in response to an external stimulus.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002409") +AnnotationAssertion(rdfs:label "Langerhans cell chemotaxis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + # Class: (production of molecular mediator of immune response) AnnotationAssertion(Annotation( "GOC:add") Annotation( "GO_REF:0000022") Annotation( "ISBN:0781735149") "The synthesis or release of any molecular mediator of the immune response, resulting in an increase in its intracellular or extracellular levels.") @@ -28233,6 +47957,223 @@ AnnotationAssertion(rdfs:label "prod SubClassOf( ) SubClassOf( ) +# Class: (histamine secretion involved in inflammatory response) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") "The regulated release of histamine by a cell as part of an inflammatory response.") +AnnotationAssertion( "histamine secretion involved in acute inflammatory response") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002441") +AnnotationAssertion(rdfs:label "histamine secretion involved in inflammatory response") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (serotonin secretion involved in inflammatory response) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") "The regulated release of serotonin by a cell as part of an inflammatory response.") +AnnotationAssertion( "serotonin secretion involved in acute inflammatory response") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:tb") "serotonin release involved in inflammatory response") +AnnotationAssertion( "GO:0002442") +AnnotationAssertion(rdfs:label "serotonin secretion involved in inflammatory response") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (leukocyte mediated immunity) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "GO_REF:0000022") Annotation( "ISBN:0781735149") "Any process involved in the carrying out of an immune response by a leukocyte.") +AnnotationAssertion( "GO:0019723") +AnnotationAssertion( "GO:0042087") +AnnotationAssertion( "immune cell effector process") +AnnotationAssertion( "immune cell mediated immunity") +AnnotationAssertion( "leucocyte immune effector process") +AnnotationAssertion( "leucocyte mediated immunity") +AnnotationAssertion( "leukocyte immune effector process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "cell-mediated immune response") +AnnotationAssertion( "cellular immune response") +AnnotationAssertion( "GO:0002443") +AnnotationAssertion(rdfs:label "leukocyte mediated immunity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectAllValuesFrom( )) + +# Class: (myeloid leukocyte mediated immunity) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "GO_REF:0000022") Annotation( "ISBN:0781735149") "Any process involved in the carrying out of an immune response by a myeloid leukocyte.") +AnnotationAssertion( "myeloid leucocyte immune effector process") +AnnotationAssertion( "myeloid leucocyte mediated immunity") +AnnotationAssertion( "myeloid leukocyte immune effector process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002444") +AnnotationAssertion(rdfs:label "myeloid leukocyte mediated immunity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (neutrophil mediated immunity) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "GO_REF:0000022") Annotation( "ISBN:0781735149") "Any process involved in the carrying out of an immune response by a neutrophil.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002446") +AnnotationAssertion(rdfs:label "neutrophil mediated immunity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (lymphocyte mediated immunity) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "GO_REF:0000022") Annotation( "ISBN:0781735149") "Any process involved in the carrying out of an immune response by a lymphocyte.") +AnnotationAssertion( "cell-mediated immunity") +AnnotationAssertion( "cellular immune response") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002449") +AnnotationAssertion(rdfs:label "lymphocyte mediated immunity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (B cell antigen processing and presentation) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") Annotation( "PMID:15771591") "The process in which a B cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.") +AnnotationAssertion( "B lymphocyte antigen processing and presentation") +AnnotationAssertion( "B-cell antigen processing and presentation") +AnnotationAssertion( "B-lymphocyte antigen processing and presentation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002450") +AnnotationAssertion(rdfs:label "B cell antigen processing and presentation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (T cell mediated immunity) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "GO_REF:0000022") Annotation( "ISBN:0781735149") "Any process involved in the carrying out of an immune response by a T cell.") +AnnotationAssertion( "cell-mediated immunity") +AnnotationAssertion( "cellular immune response") +AnnotationAssertion( "T lymphocyte mediated immunity") +AnnotationAssertion( "T-cell mediated immunity") +AnnotationAssertion( "T-lymphocyte mediated immunity") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002456") +AnnotationAssertion(rdfs:label "T cell mediated immunity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (T cell antigen processing and presentation) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "PMID:11417857") Annotation( "PMID:15120183") "The process in which a T cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.") +AnnotationAssertion( "T lymphocyte antigen processing and presentation") +AnnotationAssertion( "T-cell antigen processing and presentation") +AnnotationAssertion( "T-lymphocyte antigen processing and presentation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002457") +AnnotationAssertion(rdfs:label "T cell antigen processing and presentation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:mtg_sensu") Annotation( "ISBN:0781735149") Annotation( "ISBN:1405196831") "An immune response mediated by lymphocytes expressing specific receptors for antigen produced through a somatic diversification process that includes somatic recombination of germline gene segments encoding immunoglobulin superfamily domains. Recombined receptors for antigen encoded by immunoglobulin superfamily domains include T cell receptors and immunoglobulins (antibodies) produced by B cells. The first encounter with antigen elicits a primary immune response that is slow and not of great magnitude. T and B cells selected by antigen become activated and undergo clonal expansion. A fraction of antigen-reactive T and B cells become memory cells, whereas others differentiate into effector cells. The memory cells generated during the primary response enable a much faster and stronger secondary immune response upon subsequent exposures to the same antigen (immunological memory). An example of this is the adaptive immune response found in Mus musculus.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002460") +AnnotationAssertion(rdfs:label "adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains") +SubClassOf( ) + +# Class: (germinal center formation) + +AnnotationAssertion(Annotation( "GOC:jal") Annotation( "GO_REF:0000022") Annotation( "ISBN:081533642X") "The process in which germinal centers form. A germinal center is a specialized microenvironment formed when activated B cells enter lymphoid follicles. Germinal centers are the foci for B cell proliferation and somatic hypermutation.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002467") +AnnotationAssertion(rdfs:label "germinal center formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (dendritic cell antigen processing and presentation) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") Annotation( "PMID:15771591") "The process in which a dendritic cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002468") +AnnotationAssertion(rdfs:label "dendritic cell antigen processing and presentation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (myeloid dendritic cell antigen processing and presentation) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") Annotation( "PMID:15771591") "The process in which a myeloid dendritic cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002469") +AnnotationAssertion(rdfs:label "myeloid dendritic cell antigen processing and presentation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (monocyte antigen processing and presentation) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "PMID:11200054") "The process in which a monocyte expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002471") +AnnotationAssertion(rdfs:label "monocyte antigen processing and presentation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (macrophage antigen processing and presentation) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") Annotation( "PMID:15771591") "The process in which a macrophage expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002472") +AnnotationAssertion(rdfs:label "macrophage antigen processing and presentation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (antigen processing and presentation of peptide antigen via MHC class II) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") Annotation( "PMID:15531770") Annotation( "PMID:15771591") "The process in which an antigen-presenting cell expresses a peptide antigen on its cell surface in association with an MHC class II protein complex. The peptide antigen is typically, but not always, processed from a whole protein.") +AnnotationAssertion( "peptide antigen processing and presentation via MHC class II") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002495") +AnnotationAssertion(rdfs:label "antigen processing and presentation of peptide antigen via MHC class II") +SubClassOf( ) +SubClassOf( ) + +# Class: (proteolysis associated with antigen processing and presentation) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") Annotation( "PMID:15224092") Annotation( "PMID:15771591") "The hydrolysis of a peptide bond or bonds within a protein contributing to antigen processing and presentation.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002496") +AnnotationAssertion(rdfs:label "proteolysis associated with antigen processing and presentation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (proteolysis within lysosome associated with antigen processing and presentation) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") Annotation( "PMID:15771591") "The hydrolysis of a peptide bond or bonds within a protein by lysosomal resident proteases contributing to antigen processing and presentation.") +AnnotationAssertion( "lysosomal proteolysis associated with antigen processing and presentation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002500") +AnnotationAssertion(rdfs:label "proteolysis within lysosome associated with antigen processing and presentation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (antigen processing and presentation of peptide or polysaccharide antigen via MHC class II) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") Annotation( "PMID:15531770") Annotation( "PMID:15771591") Annotation( "PMID:16153240") "The process in which an antigen-presenting cell expresses antigen (peptide or polysaccharide) on its cell surface in association with an MHC class II protein complex.") +AnnotationAssertion( "peptide or polysaccharide antigen processing and presentation of via MHC class II") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002504") +AnnotationAssertion(rdfs:label "antigen processing and presentation of peptide or polysaccharide antigen via MHC class II") +SubClassOf( ) + +# Class: (immune system development) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:dph") "The process whose specific outcome is the progression of an organismal system whose objective is to provide calibrated responses by an organism to a potential internal or invasive threat, over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002520") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "immune system development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + # Class: (leukocyte differentiation) AnnotationAssertion(Annotation( "CL:0000738") Annotation( "GOC:add") Annotation( "PMID:16551264") "The process in which a relatively unspecialized hemopoietic precursor cell acquires the specialized features of a leukocyte. A leukocyte is an achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue.") @@ -28241,9 +48182,1281 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0002521") AnnotationAssertion(rdfs:label "leukocyte differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (leukocyte migration involved in immune response) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") Annotation( "PMID:14680625") Annotation( "PMID:14708592") Annotation( "PMID:7507411") Annotation( "PMID:8600538") "The movement of a leukocyte within or between different tissues and organs of the body as part of an immune response.") +AnnotationAssertion( "immune cell migration during immune response") +AnnotationAssertion( "immune cell trafficking during immune response") +AnnotationAssertion( "leucocyte migration during immune response") +AnnotationAssertion( "leucocyte trafficking during immune response") +AnnotationAssertion( "leukocyte trafficking during immune response") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002522") +AnnotationAssertion(rdfs:label "leukocyte migration involved in immune response") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (leukocyte migration involved in inflammatory response) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") Annotation( "PMID:14680625") Annotation( "PMID:14708592") Annotation( "PMID:7507411") Annotation( "PMID:8600538") "The movement of a leukocyte within or between different tissues and organs of the body contributing to an inflammatory response.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "immune cell migration during inflammatory response") +AnnotationAssertion( "immune cell trafficking during inflammatory response") +AnnotationAssertion( "leucocyte migration during inflammatory response") +AnnotationAssertion( "leucocyte trafficking during inflammatory response") +AnnotationAssertion(Annotation( "GOC:dph") "leukocyte migration during inflammatory response") +AnnotationAssertion( "leukocyte trafficking during inflammatory response") +AnnotationAssertion( "GO:0002523") +AnnotationAssertion(rdfs:label "leukocyte migration involved in inflammatory response") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (production of molecular mediator involved in inflammatory response) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:dph") Annotation( "GOC:tb") Annotation( "ISBN:0781735149") "The synthesis or release of any molecular mediator of the inflammatory response following an inflammatory stimulus, resulting in an increase in its intracellular or extracellular levels.") +AnnotationAssertion( "production of molecular mediator involved in acute inflammatory response") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "production of cellular mediator of acute inflammation") +AnnotationAssertion( "GO:0002532") +AnnotationAssertion(rdfs:label "production of molecular mediator involved in inflammatory response") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cytokine production involved in inflammatory response) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") "The synthesis or release of a cytokine following a inflammatory stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels.") +AnnotationAssertion( "cytokine production involved in acute inflammatory response") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002534") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "cytokine production involved in inflammatory response") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (monocyte chemotaxis) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "PMID:11696603") Annotation( "PMID:15173832") "The movement of a monocyte in response to an external stimulus.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002548") +AnnotationAssertion(rdfs:label "monocyte chemotaxis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (serotonin secretion by platelet) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") "The regulated release of serotonin by a platelet or group of platelets.") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:tb") "serotonin release by platelet") +AnnotationAssertion( "GO:0002554") +AnnotationAssertion(rdfs:label "serotonin secretion by platelet") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (histamine secretion by platelet) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "PMID:9117517") "The regulated release of histamine by a platelet or group of platelets.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002555") +AnnotationAssertion(rdfs:label "histamine secretion by platelet") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (somatic diversification of immune receptors via germline recombination within a single locus) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") Annotation( "PMID:16102575") Annotation( "PMID:16166509") "The process in which immune receptor genes are diversified through recombination of the germline genetic elements within a single genetic locus.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002562") +AnnotationAssertion(rdfs:label "somatic diversification of immune receptors via germline recombination within a single locus") +SubClassOf( ) +SubClassOf( ) + +# Class: (somatic diversification of immune receptors via somatic mutation) + +AnnotationAssertion(Annotation( "ISBN:0781735149") Annotation( "PMID:16102575") "The process in which immune receptor genes are diversified through somatic mutation.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002566") +AnnotationAssertion(rdfs:label "somatic diversification of immune receptors via somatic mutation") +SubClassOf( ) + +# Class: (pro-T cell differentiation) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") "The process in which a precursor cell type acquires the specialized features of a pro-T cell. Pro-T cells are the earliest stage of the T cell lineage but are not fully committed.") +AnnotationAssertion( "pro-T lymphocyte differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002572") +AnnotationAssertion(rdfs:label "pro-T cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (myeloid leukocyte differentiation) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "PMID:16551251") "The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of any cell of the myeloid leukocyte lineage.") +AnnotationAssertion( "myeloid leucocyte differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002573") +AnnotationAssertion(rdfs:label "myeloid leukocyte differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (thrombocyte differentiation) + +AnnotationAssertion(Annotation( "GOC:add") "The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a thrombocyte, a nucleated cell found in all vertebrates but mammals involved in hemostasis.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002574") +AnnotationAssertion(rdfs:comment "Note that platelets are the non-nucleated mammalian functional equivalent of the nucleated thrombocytes of non-mammalian vertebrates and are sometimes also referred to as thrombocytes. Platelet formation in mammals is covered by the biological_process term platelet formation ; GO:0030220.") +AnnotationAssertion(rdfs:label "thrombocyte differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (platelet degranulation) + +AnnotationAssertion(Annotation( "GOC:add") "The regulated exocytosis of secretory granules containing preformed mediators such as histamine and serotonin by a platelet.") +AnnotationAssertion( "platelet exocytosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002576") +AnnotationAssertion(rdfs:label "platelet degranulation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of antigen processing and presentation) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that modulates the frequency, rate, or extent of antigen processing and presentation.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002577") +AnnotationAssertion(rdfs:label "regulation of antigen processing and presentation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of antigen processing and presentation) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation.") +AnnotationAssertion( "down regulation of antigen processing and presentation") +AnnotationAssertion( "down-regulation of antigen processing and presentation") +AnnotationAssertion( "downregulation of antigen processing and presentation") +AnnotationAssertion( "inhibition of antigen processing and presentation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002578") +AnnotationAssertion(rdfs:label "negative regulation of antigen processing and presentation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of antigen processing and presentation) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation.") +AnnotationAssertion( "up regulation of antigen processing and presentation") +AnnotationAssertion( "up-regulation of antigen processing and presentation") +AnnotationAssertion( "upregulation of antigen processing and presentation") +AnnotationAssertion( "activation of antigen processing and presentation") +AnnotationAssertion( "stimulation of antigen processing and presentation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002579") +AnnotationAssertion(rdfs:label "positive regulation of antigen processing and presentation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that modulates the frequency, rate, or extent of antigen processing and presentation of antigen (peptide or polysaccharide) via MHC class II.") +AnnotationAssertion( "regulation of peptide or polysaccharide antigen processing and presentation via MHC class II") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002580") +AnnotationAssertion(rdfs:label "regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of antigen (peptide or polysaccharide) via MHC class II.") +AnnotationAssertion( "down regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II") +AnnotationAssertion( "down-regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II") +AnnotationAssertion( "downregulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II") +AnnotationAssertion( "negative regulation of peptide or polysaccharide antigen processing and presentation via MHC class II") +AnnotationAssertion( "inhibition of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002581") +AnnotationAssertion(rdfs:label "negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of antigen (peptide or polysaccharide) via MHC class II.") +AnnotationAssertion( "positive regulation of peptide or polysaccharide antigen processing and presentation via MHC class II") +AnnotationAssertion( "up regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II") +AnnotationAssertion( "up-regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II") +AnnotationAssertion( "upregulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II") +AnnotationAssertion( "activation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II") +AnnotationAssertion( "stimulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002582") +AnnotationAssertion(rdfs:label "positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of antigen processing and presentation of peptide antigen) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that modulates the frequency, rate, or extent of antigen processing and presentation of peptide antigen.") +AnnotationAssertion( "regulation of peptide antigen processing and presentation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002583") +AnnotationAssertion(rdfs:label "regulation of antigen processing and presentation of peptide antigen") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of antigen processing and presentation of peptide antigen) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of peptide antigen.") +AnnotationAssertion( "down regulation of antigen processing and presentation of peptide antigen") +AnnotationAssertion( "down-regulation of antigen processing and presentation of peptide antigen") +AnnotationAssertion( "downregulation of antigen processing and presentation of peptide antigen") +AnnotationAssertion( "negative regulation of peptide antigen processing and presentation") +AnnotationAssertion( "inhibition of antigen processing and presentation of peptide antigen") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002584") +AnnotationAssertion(rdfs:label "negative regulation of antigen processing and presentation of peptide antigen") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of antigen processing and presentation of peptide antigen) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of peptide antigen.") +AnnotationAssertion( "positive regulation of peptide antigen processing and presentation") +AnnotationAssertion( "up regulation of antigen processing and presentation of peptide antigen") +AnnotationAssertion( "up-regulation of antigen processing and presentation of peptide antigen") +AnnotationAssertion( "upregulation of antigen processing and presentation of peptide antigen") +AnnotationAssertion( "activation of antigen processing and presentation of peptide antigen") +AnnotationAssertion( "stimulation of antigen processing and presentation of peptide antigen") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002585") +AnnotationAssertion(rdfs:label "positive regulation of antigen processing and presentation of peptide antigen") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of antigen processing and presentation of peptide antigen via MHC class II) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that modulates the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class II.") +AnnotationAssertion( "regulation of peptide antigen processing and presentation via MHC class II") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002586") +AnnotationAssertion(rdfs:label "regulation of antigen processing and presentation of peptide antigen via MHC class II") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of antigen processing and presentation of peptide antigen via MHC class II) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class II.") +AnnotationAssertion( "down regulation of antigen processing and presentation of peptide antigen via MHC class II") +AnnotationAssertion( "down-regulation of antigen processing and presentation of peptide antigen via MHC class II") +AnnotationAssertion( "downregulation of antigen processing and presentation of peptide antigen via MHC class II") +AnnotationAssertion( "negative regulation of peptide antigen processing and presentation via MHC class II") +AnnotationAssertion( "inhibition of antigen processing and presentation of peptide antigen via MHC class II") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002587") +AnnotationAssertion(rdfs:label "negative regulation of antigen processing and presentation of peptide antigen via MHC class II") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of antigen processing and presentation of peptide antigen via MHC class II) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class II.") +AnnotationAssertion( "positive regulation of peptide antigen processing and presentation via MHC class II") +AnnotationAssertion( "up regulation of antigen processing and presentation of peptide antigen via MHC class II") +AnnotationAssertion( "up-regulation of antigen processing and presentation of peptide antigen via MHC class II") +AnnotationAssertion( "upregulation of antigen processing and presentation of peptide antigen via MHC class II") +AnnotationAssertion( "activation of antigen processing and presentation of peptide antigen via MHC class II") +AnnotationAssertion( "stimulation of antigen processing and presentation of peptide antigen via MHC class II") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002588") +AnnotationAssertion(rdfs:label "positive regulation of antigen processing and presentation of peptide antigen via MHC class II") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of dendritic cell antigen processing and presentation) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that modulates the frequency, rate, or extent of dendritic cell antigen processing and presentation.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002604") +AnnotationAssertion(rdfs:label "regulation of dendritic cell antigen processing and presentation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of dendritic cell antigen processing and presentation) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that stops, prevents, or reduces the frequency, rate, or extent of dendritic cell antigen processing and presentation.") +AnnotationAssertion( "down regulation of dendritic cell antigen processing and presentation") +AnnotationAssertion( "down-regulation of dendritic cell antigen processing and presentation") +AnnotationAssertion( "downregulation of dendritic cell antigen processing and presentation") +AnnotationAssertion( "inhibition of dendritic cell antigen processing and presentation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002605") +AnnotationAssertion(rdfs:label "negative regulation of dendritic cell antigen processing and presentation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of dendritic cell antigen processing and presentation) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that activates or increases the frequency, rate, or extent of dendritic cell antigen processing and presentation.") +AnnotationAssertion( "up regulation of dendritic cell antigen processing and presentation") +AnnotationAssertion( "up-regulation of dendritic cell antigen processing and presentation") +AnnotationAssertion( "upregulation of dendritic cell antigen processing and presentation") +AnnotationAssertion( "activation of dendritic cell antigen processing and presentation") +AnnotationAssertion( "stimulation of dendritic cell antigen processing and presentation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002606") +AnnotationAssertion(rdfs:label "positive regulation of dendritic cell antigen processing and presentation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of myeloid dendritic cell antigen processing and presentation) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that modulates the frequency, rate, or extent of myeloid dendritic cell antigen processing and presentation.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002607") +AnnotationAssertion(rdfs:label "regulation of myeloid dendritic cell antigen processing and presentation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of myeloid dendritic cell antigen processing and presentation) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid dendritic cell antigen processing and presentation.") +AnnotationAssertion( "down regulation of myeloid dendritic cell antigen processing and presentation") +AnnotationAssertion( "down-regulation of myeloid dendritic cell antigen processing and presentation") +AnnotationAssertion( "downregulation of myeloid dendritic cell antigen processing and presentation") +AnnotationAssertion( "inhibition of myeloid dendritic cell antigen processing and presentation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002608") +AnnotationAssertion(rdfs:label "negative regulation of myeloid dendritic cell antigen processing and presentation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of myeloid dendritic cell antigen processing and presentation) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that activates or increases the frequency, rate, or extent of myeloid dendritic cell antigen processing and presentation.") +AnnotationAssertion( "up regulation of myeloid dendritic cell antigen processing and presentation") +AnnotationAssertion( "up-regulation of myeloid dendritic cell antigen processing and presentation") +AnnotationAssertion( "upregulation of myeloid dendritic cell antigen processing and presentation") +AnnotationAssertion( "activation of myeloid dendritic cell antigen processing and presentation") +AnnotationAssertion( "stimulation of myeloid dendritic cell antigen processing and presentation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002609") +AnnotationAssertion(rdfs:label "positive regulation of myeloid dendritic cell antigen processing and presentation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of monocyte antigen processing and presentation) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that modulates the frequency, rate, or extent of monocyte antigen processing and presentation.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002613") +AnnotationAssertion(rdfs:label "regulation of monocyte antigen processing and presentation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of monocyte antigen processing and presentation) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that stops, prevents, or reduces the frequency, rate, or extent of monocyte antigen processing and presentation.") +AnnotationAssertion( "down regulation of monocyte antigen processing and presentation") +AnnotationAssertion( "down-regulation of monocyte antigen processing and presentation") +AnnotationAssertion( "downregulation of monocyte antigen processing and presentation") +AnnotationAssertion( "inhibition of monocyte antigen processing and presentation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002614") +AnnotationAssertion(rdfs:label "negative regulation of monocyte antigen processing and presentation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of monocyte antigen processing and presentation) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that activates or increases the frequency, rate, or extent of monocyte antigen processing and presentation.") +AnnotationAssertion( "up regulation of monocyte antigen processing and presentation") +AnnotationAssertion( "up-regulation of monocyte antigen processing and presentation") +AnnotationAssertion( "upregulation of monocyte antigen processing and presentation") +AnnotationAssertion( "activation of monocyte antigen processing and presentation") +AnnotationAssertion( "stimulation of monocyte antigen processing and presentation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002615") +AnnotationAssertion(rdfs:label "positive regulation of monocyte antigen processing and presentation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of macrophage antigen processing and presentation) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that modulates the frequency, rate, or extent of macrophage antigen processing and presentation.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002616") +AnnotationAssertion(rdfs:label "regulation of macrophage antigen processing and presentation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of macrophage antigen processing and presentation) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that stops, prevents, or reduces the frequency, rate, or extent of macrophage antigen processing and presentation.") +AnnotationAssertion( "down regulation of macrophage antigen processing and presentation") +AnnotationAssertion( "down-regulation of macrophage antigen processing and presentation") +AnnotationAssertion( "downregulation of macrophage antigen processing and presentation") +AnnotationAssertion( "inhibition of macrophage antigen processing and presentation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002617") +AnnotationAssertion(rdfs:label "negative regulation of macrophage antigen processing and presentation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of macrophage antigen processing and presentation) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that activates or increases the frequency, rate, or extent of macrophage antigen processing and presentation.") +AnnotationAssertion( "up regulation of macrophage antigen processing and presentation") +AnnotationAssertion( "up-regulation of macrophage antigen processing and presentation") +AnnotationAssertion( "upregulation of macrophage antigen processing and presentation") +AnnotationAssertion( "activation of macrophage antigen processing and presentation") +AnnotationAssertion( "stimulation of macrophage antigen processing and presentation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002618") +AnnotationAssertion(rdfs:label "positive regulation of macrophage antigen processing and presentation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of B cell antigen processing and presentation) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that modulates the frequency, rate, or extent of B cell antigen processing and presentation.") +AnnotationAssertion( "regulation of B lymphocyte antigen processing and presentation") +AnnotationAssertion( "regulation of B-cell antigen processing and presentation") +AnnotationAssertion( "regulation of B-lymphocyte antigen processing and presentation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002622") +AnnotationAssertion(rdfs:label "regulation of B cell antigen processing and presentation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (negative regulation of B cell antigen processing and presentation) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell antigen processing and presentation.") +AnnotationAssertion( "down regulation of B cell antigen processing and presentation") +AnnotationAssertion( "down-regulation of B cell antigen processing and presentation") +AnnotationAssertion( "downregulation of B cell antigen processing and presentation") +AnnotationAssertion( "negative regulation of B lymphocyte antigen processing and presentation") +AnnotationAssertion( "negative regulation of B-cell antigen processing and presentation") +AnnotationAssertion( "negative regulation of B-lymphocyte antigen processing and presentation") +AnnotationAssertion( "inhibition of B cell antigen processing and presentation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002623") +AnnotationAssertion(rdfs:label "negative regulation of B cell antigen processing and presentation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (positive regulation of B cell antigen processing and presentation) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that activates or increases the frequency, rate, or extent of B cell antigen processing and presentation.") +AnnotationAssertion( "positive regulation of B lymphocyte antigen processing and presentation") +AnnotationAssertion( "positive regulation of B-cell antigen processing and presentation") +AnnotationAssertion( "positive regulation of B-lymphocyte antigen processing and presentation") +AnnotationAssertion( "up regulation of B cell antigen processing and presentation") +AnnotationAssertion( "up-regulation of B cell antigen processing and presentation") +AnnotationAssertion( "upregulation of B cell antigen processing and presentation") +AnnotationAssertion( "activation of B cell antigen processing and presentation") +AnnotationAssertion( "stimulation of B cell antigen processing and presentation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002624") +AnnotationAssertion(rdfs:label "positive regulation of B cell antigen processing and presentation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of T cell antigen processing and presentation) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that modulates the frequency, rate, or extent of T cell antigen processing and presentation.") +AnnotationAssertion( "regulation of T lymphocyte antigen processing and presentation") +AnnotationAssertion( "regulation of T-cell antigen processing and presentation") +AnnotationAssertion( "regulation of T-lymphocyte antigen processing and presentation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002625") +AnnotationAssertion(rdfs:label "regulation of T cell antigen processing and presentation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (negative regulation of T cell antigen processing and presentation) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell antigen processing and presentation.") +AnnotationAssertion( "down regulation of T cell antigen processing and presentation") +AnnotationAssertion( "down-regulation of T cell antigen processing and presentation") +AnnotationAssertion( "downregulation of T cell antigen processing and presentation") +AnnotationAssertion( "negative regulation of T lymphocyte antigen processing and presentation") +AnnotationAssertion( "negative regulation of T-cell antigen processing and presentation") +AnnotationAssertion( "negative regulation of T-lymphocyte antigen processing and presentation") +AnnotationAssertion( "inhibition of T cell antigen processing and presentation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002626") +AnnotationAssertion(rdfs:label "negative regulation of T cell antigen processing and presentation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (positive regulation of T cell antigen processing and presentation) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that activates or increases the frequency, rate, or extent of T cell antigen processing and presentation.") +AnnotationAssertion( "positive regulation of T lymphocyte antigen processing and presentation") +AnnotationAssertion( "positive regulation of T-cell antigen processing and presentation") +AnnotationAssertion( "positive regulation of T-lymphocyte antigen processing and presentation") +AnnotationAssertion( "up regulation of T cell antigen processing and presentation") +AnnotationAssertion( "up-regulation of T cell antigen processing and presentation") +AnnotationAssertion( "upregulation of T cell antigen processing and presentation") +AnnotationAssertion( "activation of T cell antigen processing and presentation") +AnnotationAssertion( "stimulation of T cell antigen processing and presentation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002627") +AnnotationAssertion(rdfs:label "positive regulation of T cell antigen processing and presentation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (regulation of proteolysis associated with antigen processing and presentation) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that modulates the frequency, rate, or extent of proteolysis associated with antigen processing and presentation.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002628") +AnnotationAssertion(rdfs:label "regulation of proteolysis associated with antigen processing and presentation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of proteolysis associated with antigen processing and presentation) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that stops, prevents, or reduces the frequency, rate, or extent of proteolysis associated with antigen processing and presentation.") +AnnotationAssertion( "down regulation of proteolysis associated with antigen processing and presentation") +AnnotationAssertion( "down-regulation of proteolysis associated with antigen processing and presentation") +AnnotationAssertion( "downregulation of proteolysis associated with antigen processing and presentation") +AnnotationAssertion( "inhibition of proteolysis associated with antigen processing and presentation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002629") +AnnotationAssertion(rdfs:label "negative regulation of proteolysis associated with antigen processing and presentation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (positive regulation of proteolysis associated with antigen processing and presentation) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that activates or increases the frequency, rate, or extent of proteolysis associated with antigen processing and presentation.") +AnnotationAssertion( "up regulation of proteolysis associated with antigen processing and presentation") +AnnotationAssertion( "up-regulation of proteolysis associated with antigen processing and presentation") +AnnotationAssertion( "upregulation of proteolysis associated with antigen processing and presentation") +AnnotationAssertion( "activation of proteolysis associated with antigen processing and presentation") +AnnotationAssertion( "stimulation of proteolysis associated with antigen processing and presentation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002630") +AnnotationAssertion(rdfs:label "positive regulation of proteolysis associated with antigen processing and presentation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (regulation of germinal center formation) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that modulates the frequency, rate, or extent of germinal center formation.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002634") +AnnotationAssertion(rdfs:label "regulation of germinal center formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (negative regulation of germinal center formation) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that stops, prevents, or reduces the frequency, rate, or extent of germinal center formation.") +AnnotationAssertion( "down regulation of germinal center formation") +AnnotationAssertion( "down-regulation of germinal center formation") +AnnotationAssertion( "downregulation of germinal center formation") +AnnotationAssertion( "inhibition of germinal center formation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002635") +AnnotationAssertion(rdfs:label "negative regulation of germinal center formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of germinal center formation) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that activates or increases the frequency, rate, or extent of germinal center formation.") +AnnotationAssertion( "up regulation of germinal center formation") +AnnotationAssertion( "up-regulation of germinal center formation") +AnnotationAssertion( "upregulation of germinal center formation") +AnnotationAssertion( "activation of germinal center formation") +AnnotationAssertion( "stimulation of germinal center formation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002636") +AnnotationAssertion(rdfs:label "positive regulation of germinal center formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of immunoglobulin production) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that modulates the frequency, rate, or extent of immunoglobulin production.") +AnnotationAssertion( "GO:0002640") +AnnotationAssertion( "GO:0051023") +AnnotationAssertion( "regulation of antibody production") +AnnotationAssertion( "regulation of immunoglobulin biosynthetic process") +AnnotationAssertion( "regulation of immunoglobulin secretion") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002637") +AnnotationAssertion(rdfs:label "regulation of immunoglobulin production") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (negative regulation of immunoglobulin production) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that stops, prevents, or reduces the frequency, rate, or extent of immunoglobulin production.") +AnnotationAssertion( "GO:0002641") +AnnotationAssertion( "GO:0051025") +AnnotationAssertion( "down regulation of immunoglobulin production") +AnnotationAssertion( "down-regulation of immunoglobulin production") +AnnotationAssertion( "downregulation of immunoglobulin production") +AnnotationAssertion( "inhibition of immunoglobulin production") +AnnotationAssertion( "negative regulation of immunoglobulin biosynthetic process") +AnnotationAssertion( "negative regulation of immunoglobulin secretion") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002638") +AnnotationAssertion(rdfs:label "negative regulation of immunoglobulin production") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of immunoglobulin production) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that activates or increases the frequency, rate, or extent of immunoglobulin production.") +AnnotationAssertion( "GO:0002642") +AnnotationAssertion( "GO:0051024") +AnnotationAssertion( "up regulation of immunoglobulin production") +AnnotationAssertion( "up-regulation of immunoglobulin production") +AnnotationAssertion( "upregulation of immunoglobulin production") +AnnotationAssertion( "activation of immunoglobulin production") +AnnotationAssertion( "positive regulation of immunoglobulin biosynthetic process") +AnnotationAssertion( "positive regulation of immunoglobulin secretion") +AnnotationAssertion( "stimulation of immunoglobulin production") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002639") +AnnotationAssertion(rdfs:label "positive regulation of immunoglobulin production") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of immune system process) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that modulates the frequency, rate, or extent of an immune system process.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002682") +AnnotationAssertion(rdfs:label "regulation of immune system process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (negative regulation of immune system process) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune system process.") +AnnotationAssertion( "down regulation of immune system process") +AnnotationAssertion( "down-regulation of immune system process") +AnnotationAssertion( "downregulation of immune system process") +AnnotationAssertion( "inhibition of immune system process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002683") +AnnotationAssertion(rdfs:label "negative regulation of immune system process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of immune system process) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that activates or increases the frequency, rate, or extent of an immune system process.") +AnnotationAssertion( "up regulation of immune system process") +AnnotationAssertion( "up-regulation of immune system process") +AnnotationAssertion( "upregulation of immune system process") +AnnotationAssertion( "activation of immune system process") +AnnotationAssertion( "stimulation of immune system process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002684") +AnnotationAssertion(rdfs:label "positive regulation of immune system process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of leukocyte migration) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that modulates the frequency, rate, or extent of leukocyte migration.") +AnnotationAssertion( "regulation of immune cell migration") +AnnotationAssertion( "regulation of leucocyte migration") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002685") +AnnotationAssertion(rdfs:label "regulation of leukocyte migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of leukocyte migration) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte migration.") +AnnotationAssertion( "down regulation of leukocyte migration") +AnnotationAssertion( "down-regulation of leukocyte migration") +AnnotationAssertion( "downregulation of leukocyte migration") +AnnotationAssertion( "negative regulation of immune cell migration") +AnnotationAssertion( "negative regulation of leucocyte migration") +AnnotationAssertion( "inhibition of leukocyte migration") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002686") +AnnotationAssertion(rdfs:label "negative regulation of leukocyte migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of leukocyte migration) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that activates or increases the frequency, rate, or extent of leukocyte migration.") +AnnotationAssertion( "positive regulation of immune cell migration") +AnnotationAssertion( "positive regulation of leucocyte migration") +AnnotationAssertion( "up regulation of leukocyte migration") +AnnotationAssertion( "up-regulation of leukocyte migration") +AnnotationAssertion( "upregulation of leukocyte migration") +AnnotationAssertion( "activation of leukocyte migration") +AnnotationAssertion( "stimulation of leukocyte migration") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002687") +AnnotationAssertion(rdfs:label "positive regulation of leukocyte migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of leukocyte chemotaxis) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that modulates the frequency, rate, or extent of leukocyte chemotaxis.") +AnnotationAssertion( "regulation of immune cell chemotaxis") +AnnotationAssertion( "regulation of leucocyte chemotaxis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002688") +AnnotationAssertion(rdfs:label "regulation of leukocyte chemotaxis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of leukocyte chemotaxis) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte chemotaxis.") +AnnotationAssertion( "down regulation of leukocyte chemotaxis") +AnnotationAssertion( "down-regulation of leukocyte chemotaxis") +AnnotationAssertion( "downregulation of leukocyte chemotaxis") +AnnotationAssertion( "negative regulation of immune cell chemotaxis") +AnnotationAssertion( "negative regulation of leucocyte chemotaxis") +AnnotationAssertion( "inhibition of leukocyte chemotaxis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002689") +AnnotationAssertion(rdfs:label "negative regulation of leukocyte chemotaxis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of leukocyte chemotaxis) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that activates or increases the frequency, rate, or extent of leukocyte chemotaxis.") +AnnotationAssertion( "positive regulation of immune cell chemotaxis") +AnnotationAssertion( "positive regulation of leucocyte chemotaxis") +AnnotationAssertion( "up regulation of leukocyte chemotaxis") +AnnotationAssertion( "up-regulation of leukocyte chemotaxis") +AnnotationAssertion( "upregulation of leukocyte chemotaxis") +AnnotationAssertion( "activation of leukocyte chemotaxis") +AnnotationAssertion( "stimulation of leukocyte chemotaxis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002690") +AnnotationAssertion(rdfs:label "positive regulation of leukocyte chemotaxis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of leukocyte activation) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that modulates the frequency, rate, or extent of leukocyte activation.") +AnnotationAssertion( "regulation of immune cell activation") +AnnotationAssertion( "regulation of leucocyte activation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002694") +AnnotationAssertion(rdfs:label "regulation of leukocyte activation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of leukocyte activation) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte activation.") +AnnotationAssertion( "down regulation of leukocyte activation") +AnnotationAssertion( "down-regulation of leukocyte activation") +AnnotationAssertion( "downregulation of leukocyte activation") +AnnotationAssertion( "negative regulation of immune cell activation") +AnnotationAssertion( "negative regulation of leucocyte activation") +AnnotationAssertion( "inhibition of leukocyte activation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002695") +AnnotationAssertion(rdfs:label "negative regulation of leukocyte activation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of leukocyte activation) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that activates or increases the frequency, rate, or extent of leukocyte activation.") +AnnotationAssertion( "positive regulation of immune cell activation") +AnnotationAssertion( "positive regulation of leucocyte activation") +AnnotationAssertion( "up regulation of leukocyte activation") +AnnotationAssertion( "up-regulation of leukocyte activation") +AnnotationAssertion( "upregulation of leukocyte activation") +AnnotationAssertion( "activation of leukocyte activation") +AnnotationAssertion( "stimulation of leukocyte activation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002696") +AnnotationAssertion(rdfs:label "positive regulation of leukocyte activation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of immune effector process) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that modulates the frequency, rate, or extent of an immune effector process.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002697") +AnnotationAssertion(rdfs:label "regulation of immune effector process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (negative regulation of immune effector process) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune effector process.") +AnnotationAssertion( "down regulation of immune effector process") +AnnotationAssertion( "down-regulation of immune effector process") +AnnotationAssertion( "downregulation of immune effector process") +AnnotationAssertion( "inhibition of immune effector process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002698") +AnnotationAssertion(rdfs:label "negative regulation of immune effector process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of immune effector process) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that activates or increases the frequency, rate, or extent of an immune effector process.") +AnnotationAssertion( "up regulation of immune effector process") +AnnotationAssertion( "up-regulation of immune effector process") +AnnotationAssertion( "upregulation of immune effector process") +AnnotationAssertion( "activation of immune effector process") +AnnotationAssertion( "stimulation of immune effector process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002699") +AnnotationAssertion(rdfs:label "positive regulation of immune effector process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of production of molecular mediator of immune response) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that modulates the frequency, rate, or extent of the production of molecular mediator of immune response.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002700") +AnnotationAssertion(rdfs:label "regulation of production of molecular mediator of immune response") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (negative regulation of production of molecular mediator of immune response) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that stops, prevents, or reduces the frequency, rate, or extent of the production of molecular mediator of immune response.") +AnnotationAssertion( "down regulation of production of molecular mediator of immune response") +AnnotationAssertion( "down-regulation of production of molecular mediator of immune response") +AnnotationAssertion( "downregulation of production of molecular mediator of immune response") +AnnotationAssertion( "inhibition of production of molecular mediator of immune response") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002701") +AnnotationAssertion(rdfs:label "negative regulation of production of molecular mediator of immune response") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of production of molecular mediator of immune response) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that activates or increases the frequency, rate, or extent of the production of molecular mediator of immune response.") +AnnotationAssertion( "up regulation of production of molecular mediator of immune response") +AnnotationAssertion( "up-regulation of production of molecular mediator of immune response") +AnnotationAssertion( "upregulation of production of molecular mediator of immune response") +AnnotationAssertion( "activation of production of molecular mediator of immune response") +AnnotationAssertion( "stimulation of production of molecular mediator of immune response") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002702") +AnnotationAssertion(rdfs:label "positive regulation of production of molecular mediator of immune response") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of leukocyte mediated immunity) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that modulates the frequency, rate, or extent of leukocyte mediated immunity.") +AnnotationAssertion( "regulation of immune cell mediated immunity") +AnnotationAssertion( "regulation of leucocyte mediated immunity") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002703") +AnnotationAssertion(rdfs:label "regulation of leukocyte mediated immunity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of leukocyte mediated immunity) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte mediated immunity.") +AnnotationAssertion( "down regulation of leukocyte mediated immunity") +AnnotationAssertion( "down-regulation of leukocyte mediated immunity") +AnnotationAssertion( "downregulation of leukocyte mediated immunity") +AnnotationAssertion( "negative regulation of immune cell mediated immunity") +AnnotationAssertion( "negative regulation of leucocyte mediated immunity") +AnnotationAssertion( "inhibition of leukocyte mediated immunity") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002704") +AnnotationAssertion(rdfs:label "negative regulation of leukocyte mediated immunity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of leukocyte mediated immunity) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that activates or increases the frequency, rate, or extent of leukocyte mediated immunity.") +AnnotationAssertion( "positive regulation of immune cell mediated immunity") +AnnotationAssertion( "positive regulation of leucocyte mediated immunity") +AnnotationAssertion( "up regulation of leukocyte mediated immunity") +AnnotationAssertion( "up-regulation of leukocyte mediated immunity") +AnnotationAssertion( "upregulation of leukocyte mediated immunity") +AnnotationAssertion( "activation of leukocyte mediated immunity") +AnnotationAssertion( "stimulation of leukocyte mediated immunity") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002705") +AnnotationAssertion(rdfs:label "positive regulation of leukocyte mediated immunity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of lymphocyte mediated immunity) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that modulates the frequency, rate, or extent of lymphocyte mediated immunity.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002706") +AnnotationAssertion(rdfs:label "regulation of lymphocyte mediated immunity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of lymphocyte mediated immunity) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that stops, prevents, or reduces the frequency, rate, or extent of lymphocyte mediated immunity.") +AnnotationAssertion( "down regulation of lymphocyte mediated immunity") +AnnotationAssertion( "down-regulation of lymphocyte mediated immunity") +AnnotationAssertion( "downregulation of lymphocyte mediated immunity") +AnnotationAssertion( "inhibition of lymphocyte mediated immunity") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002707") +AnnotationAssertion(rdfs:label "negative regulation of lymphocyte mediated immunity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of lymphocyte mediated immunity) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that activates or increases the frequency, rate, or extent of lymphocyte mediated immunity.") +AnnotationAssertion( "up regulation of lymphocyte mediated immunity") +AnnotationAssertion( "up-regulation of lymphocyte mediated immunity") +AnnotationAssertion( "upregulation of lymphocyte mediated immunity") +AnnotationAssertion( "activation of lymphocyte mediated immunity") +AnnotationAssertion( "stimulation of lymphocyte mediated immunity") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002708") +AnnotationAssertion(rdfs:label "positive regulation of lymphocyte mediated immunity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of T cell mediated immunity) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that modulates the frequency, rate, or extent of T cell mediated immunity.") +AnnotationAssertion( "regulation of T lymphocyte mediated immunity") +AnnotationAssertion( "regulation of T-cell mediated immunity") +AnnotationAssertion( "regulation of T-lymphocyte mediated immunity") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002709") +AnnotationAssertion(rdfs:label "regulation of T cell mediated immunity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of T cell mediated immunity) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell mediated immunity.") +AnnotationAssertion( "down regulation of T cell mediated immunity") +AnnotationAssertion( "down-regulation of T cell mediated immunity") +AnnotationAssertion( "downregulation of T cell mediated immunity") +AnnotationAssertion( "negative regulation of T lymphocyte mediated immunity") +AnnotationAssertion( "negative regulation of T-cell mediated immunity") +AnnotationAssertion( "negative regulation of T-lymphocyte mediated immunity") +AnnotationAssertion( "inhibition of T cell mediated immunity") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002710") +AnnotationAssertion(rdfs:label "negative regulation of T cell mediated immunity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of T cell mediated immunity) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that activates or increases the frequency, rate, or extent of T cell mediated immunity.") +AnnotationAssertion( "positive regulation of T lymphocyte mediated immunity") +AnnotationAssertion( "positive regulation of T-cell mediated immunity") +AnnotationAssertion( "positive regulation of T-lymphocyte mediated immunity") +AnnotationAssertion( "up regulation of T cell mediated immunity") +AnnotationAssertion( "up-regulation of T cell mediated immunity") +AnnotationAssertion( "upregulation of T cell mediated immunity") +AnnotationAssertion( "activation of T cell mediated immunity") +AnnotationAssertion( "stimulation of T cell mediated immunity") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002711") +AnnotationAssertion(rdfs:label "positive regulation of T cell mediated immunity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of B cell mediated immunity) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that modulates the frequency, rate, or extent of B cell mediated immunity.") +AnnotationAssertion( "regulation of B lymphocyte mediated immunity") +AnnotationAssertion( "regulation of B-cell mediated immunity") +AnnotationAssertion( "regulation of B-lymphocyte mediated immunity") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002712") +AnnotationAssertion(rdfs:label "regulation of B cell mediated immunity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of B cell mediated immunity) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell mediated immunity.") +AnnotationAssertion( "down regulation of B cell mediated immunity") +AnnotationAssertion( "down-regulation of B cell mediated immunity") +AnnotationAssertion( "downregulation of B cell mediated immunity") +AnnotationAssertion( "negative regulation of B lymphocyte mediated immunity") +AnnotationAssertion( "negative regulation of B-cell mediated immunity") +AnnotationAssertion( "negative regulation of B-lymphocyte mediated immunity") +AnnotationAssertion( "inhibition of B cell mediated immunity") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002713") +AnnotationAssertion(rdfs:label "negative regulation of B cell mediated immunity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of B cell mediated immunity) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that activates or increases the frequency, rate, or extent of B cell mediated immunity.") +AnnotationAssertion( "positive regulation of B lymphocyte mediated immunity") +AnnotationAssertion( "positive regulation of B-cell mediated immunity") +AnnotationAssertion( "positive regulation of B-lymphocyte mediated immunity") +AnnotationAssertion( "up regulation of B cell mediated immunity") +AnnotationAssertion( "up-regulation of B cell mediated immunity") +AnnotationAssertion( "upregulation of B cell mediated immunity") +AnnotationAssertion( "activation of B cell mediated immunity") +AnnotationAssertion( "stimulation of B cell mediated immunity") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002714") +AnnotationAssertion(rdfs:label "positive regulation of B cell mediated immunity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of cytokine production involved in immune response) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that modulates the frequency, rate, or extent of cytokine production that contributes to an immune response.") +AnnotationAssertion( "GO:0002739") +AnnotationAssertion( "GO:0002742") +AnnotationAssertion( "regulation of cytokine biosynthetic process involved in immune response") +AnnotationAssertion( "regulation of cytokine secretion involved in immune response") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") "regulation of cytokine production during immune response") +AnnotationAssertion( "GO:0002718") +AnnotationAssertion(rdfs:label "regulation of cytokine production involved in immune response") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of cytokine production involved in immune response) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that stops, prevents, or reduces the frequency, rate, or extent of cytokine production contributing to an immune response.") +AnnotationAssertion( "GO:0002740") +AnnotationAssertion( "GO:0002743") +AnnotationAssertion( "down-regulation of cytokine production during immune response") +AnnotationAssertion( "negative regulation of cytokine biosynthetic process involved in immune response") +AnnotationAssertion( "negative regulation of cytokine secretion involved in immune response") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "down regulation of cytokine production during immune response") +AnnotationAssertion( "downregulation of cytokine production during immune response") +AnnotationAssertion( "inhibition of cytokine production during immune response") +AnnotationAssertion(Annotation( "GOC:dph") "negative regulation of cytokine production during immune response") +AnnotationAssertion( "GO:0002719") +AnnotationAssertion(rdfs:label "negative regulation of cytokine production involved in immune response") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of cytokine production involved in immune response) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that activates or increases the frequency, rate, or extent of cytokine production that contributes to an immune response.") +AnnotationAssertion( "GO:0002741") +AnnotationAssertion( "GO:0002744") +AnnotationAssertion( "activation of cytokine production during immune response") +AnnotationAssertion( "positive regulation of cytokine biosynthetic process involved in immune response") +AnnotationAssertion( "positive regulation of cytokine secretion involved in immune response") +AnnotationAssertion( "stimulation of cytokine production during immune response") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") "positive regulation of cytokine production during immune response") +AnnotationAssertion( "up regulation of cytokine production during immune response") +AnnotationAssertion( "up-regulation of cytokine production during immune response") +AnnotationAssertion( "upregulation of cytokine production during immune response") +AnnotationAssertion( "GO:0002720") +AnnotationAssertion(rdfs:label "positive regulation of cytokine production involved in immune response") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of B cell cytokine production) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that modulates the frequency, rate, or extent of B cell cytokine production.") +AnnotationAssertion( "regulation of B lymphocyte cytokine production") +AnnotationAssertion( "regulation of B-cell cytokine production") +AnnotationAssertion( "regulation of B-lymphocyte cytokine production") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002721") +AnnotationAssertion(rdfs:label "regulation of B cell cytokine production") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of B cell cytokine production) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell cytokine production.") +AnnotationAssertion( "down regulation of B cell cytokine production") +AnnotationAssertion( "down-regulation of B cell cytokine production") +AnnotationAssertion( "downregulation of B cell cytokine production") +AnnotationAssertion( "negative regulation of B lymphocyte cytokine production") +AnnotationAssertion( "negative regulation of B-cell cytokine production") +AnnotationAssertion( "negative regulation of B-lymphocyte cytokine production") +AnnotationAssertion( "inhibition of B cell cytokine production") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002722") +AnnotationAssertion(rdfs:label "negative regulation of B cell cytokine production") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of B cell cytokine production) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that activates or increases the frequency, rate, or extent of B cell cytokine production.") +AnnotationAssertion( "positive regulation of B lymphocyte cytokine production") +AnnotationAssertion( "positive regulation of B-cell cytokine production") +AnnotationAssertion( "positive regulation of B-lymphocyte cytokine production") +AnnotationAssertion( "up regulation of B cell cytokine production") +AnnotationAssertion( "up-regulation of B cell cytokine production") +AnnotationAssertion( "upregulation of B cell cytokine production") +AnnotationAssertion( "activation of B cell cytokine production") +AnnotationAssertion( "stimulation of B cell cytokine production") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002723") +AnnotationAssertion(rdfs:label "positive regulation of B cell cytokine production") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of T cell cytokine production) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that modulates the frequency, rate, or extent of T cell cytokine production.") +AnnotationAssertion( "regulation of T lymphocyte cytokine production") +AnnotationAssertion( "regulation of T-cell cytokine production") +AnnotationAssertion( "regulation of T-lymphocyte cytokine production") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002724") +AnnotationAssertion(rdfs:label "regulation of T cell cytokine production") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of T cell cytokine production) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell cytokine production.") +AnnotationAssertion( "down regulation of T cell cytokine production") +AnnotationAssertion( "down-regulation of T cell cytokine production") +AnnotationAssertion( "downregulation of T cell cytokine production") +AnnotationAssertion( "negative regulation of T lymphocyte cytokine production") +AnnotationAssertion( "negative regulation of T-cell cytokine production") +AnnotationAssertion( "negative regulation of T-lymphocyte cytokine production") +AnnotationAssertion( "inhibition of T cell cytokine production") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002725") +AnnotationAssertion(rdfs:label "negative regulation of T cell cytokine production") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of T cell cytokine production) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that activates or increases the frequency, rate, or extent of T cell cytokine production.") +AnnotationAssertion( "positive regulation of T lymphocyte cytokine production") +AnnotationAssertion( "positive regulation of T-cell cytokine production") +AnnotationAssertion( "positive regulation of T-lymphocyte cytokine production") +AnnotationAssertion( "up regulation of T cell cytokine production") +AnnotationAssertion( "up-regulation of T cell cytokine production") +AnnotationAssertion( "upregulation of T cell cytokine production") +AnnotationAssertion( "activation of T cell cytokine production") +AnnotationAssertion( "stimulation of T cell cytokine production") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002726") +AnnotationAssertion(rdfs:label "positive regulation of T cell cytokine production") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of dendritic cell cytokine production) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that modulates the frequency, rate, or extent of dendritic cell cytokine production.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002730") +AnnotationAssertion(rdfs:label "regulation of dendritic cell cytokine production") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of dendritic cell cytokine production) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that stops, prevents, or reduces the frequency, rate, or extent of dendritic cell cytokine production.") +AnnotationAssertion( "down regulation of dendritic cell cytokine production") +AnnotationAssertion( "down-regulation of dendritic cell cytokine production") +AnnotationAssertion( "downregulation of dendritic cell cytokine production") +AnnotationAssertion( "inhibition of dendritic cell cytokine production") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002731") +AnnotationAssertion(rdfs:label "negative regulation of dendritic cell cytokine production") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of dendritic cell cytokine production) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that activates or increases the frequency, rate, or extent of dendritic cell cytokine production.") +AnnotationAssertion( "up regulation of dendritic cell cytokine production") +AnnotationAssertion( "up-regulation of dendritic cell cytokine production") +AnnotationAssertion( "upregulation of dendritic cell cytokine production") +AnnotationAssertion( "activation of dendritic cell cytokine production") +AnnotationAssertion( "stimulation of dendritic cell cytokine production") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002732") +AnnotationAssertion(rdfs:label "positive regulation of dendritic cell cytokine production") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of myeloid dendritic cell cytokine production) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that modulates the frequency, rate, or extent of myeloid dendritic cell cytokine production.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002733") +AnnotationAssertion(rdfs:label "regulation of myeloid dendritic cell cytokine production") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of myeloid dendritic cell cytokine production) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid dendritic cell cytokine production.") +AnnotationAssertion( "down regulation of myeloid dendritic cell cytokine production") +AnnotationAssertion( "down-regulation of myeloid dendritic cell cytokine production") +AnnotationAssertion( "downregulation of myeloid dendritic cell cytokine production") +AnnotationAssertion( "inhibition of myeloid dendritic cell cytokine production") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002734") +AnnotationAssertion(rdfs:label "negative regulation of myeloid dendritic cell cytokine production") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of myeloid dendritic cell cytokine production) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that activates or increases the frequency, rate, or extent of myeloid dendritic cell cytokine production.") +AnnotationAssertion( "up regulation of myeloid dendritic cell cytokine production") +AnnotationAssertion( "up-regulation of myeloid dendritic cell cytokine production") +AnnotationAssertion( "upregulation of myeloid dendritic cell cytokine production") +AnnotationAssertion( "activation of myeloid dendritic cell cytokine production") +AnnotationAssertion( "stimulation of myeloid dendritic cell cytokine production") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002735") +AnnotationAssertion(rdfs:label "positive regulation of myeloid dendritic cell cytokine production") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of antimicrobial humoral response) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that modulates the frequency, rate, or extent of an antimicrobial humoral response.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002759") +AnnotationAssertion(rdfs:label "regulation of antimicrobial humoral response") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of antimicrobial humoral response) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that activates or increases the frequency, rate, or extent of an antimicrobial humoral response.") +AnnotationAssertion( "up regulation of antimicrobial humoral response") +AnnotationAssertion( "up-regulation of antimicrobial humoral response") +AnnotationAssertion( "upregulation of antimicrobial humoral response") +AnnotationAssertion( "activation of antimicrobial humoral response") +AnnotationAssertion( "stimulation of antimicrobial humoral response") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002760") +AnnotationAssertion(rdfs:label "positive regulation of antimicrobial humoral response") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of myeloid leukocyte differentiation) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that modulates the frequency, rate, or extent of myeloid leukocyte differentiation.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002761") +AnnotationAssertion(rdfs:label "regulation of myeloid leukocyte differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of myeloid leukocyte differentiation) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid leukocyte differentiation.") +AnnotationAssertion( "down regulation of myeloid leukocyte differentiation") +AnnotationAssertion( "down-regulation of myeloid leukocyte differentiation") +AnnotationAssertion( "downregulation of myeloid leukocyte differentiation") +AnnotationAssertion( "inhibition of myeloid leukocyte differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002762") +AnnotationAssertion(rdfs:label "negative regulation of myeloid leukocyte differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of myeloid leukocyte differentiation) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that activates or increases the frequency, rate, or extent of myeloid leukocyte differentiation.") +AnnotationAssertion( "up regulation of myeloid leukocyte differentiation") +AnnotationAssertion( "up-regulation of myeloid leukocyte differentiation") +AnnotationAssertion( "upregulation of myeloid leukocyte differentiation") +AnnotationAssertion( "activation of myeloid leukocyte differentiation") +AnnotationAssertion( "stimulation of myeloid leukocyte differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002763") +AnnotationAssertion(rdfs:label "positive regulation of myeloid leukocyte differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (antimicrobial peptide production) AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") Annotation( "PMID:11807545") Annotation( "PMID:15638771") "The synthesis or release of an antimicrobial peptide during an immune response, resulting in an increase in intracellular or extracellular levels. Such peptides may have protective properties against bacteria, fungi, viruses, or protozoa.") @@ -28264,15 +49477,497 @@ AnnotationAssertion(rdfs:label "anti SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (regulation of antimicrobial peptide production) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that modulates the frequency, rate, or extent of antimicrobial peptide production.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002784") +AnnotationAssertion(rdfs:label "regulation of antimicrobial peptide production") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (negative regulation of antimicrobial peptide production) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that stops, prevents, or reduces the frequency, rate, or extent of antimicrobial peptide production.") +AnnotationAssertion( "down regulation of antimicrobial peptide production") +AnnotationAssertion( "down-regulation of antimicrobial peptide production") +AnnotationAssertion( "downregulation of antimicrobial peptide production") +AnnotationAssertion( "inhibition of antimicrobial peptide production") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002785") +AnnotationAssertion(rdfs:label "negative regulation of antimicrobial peptide production") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + # Class: (peptide secretion) AnnotationAssertion(Annotation( "GOC:add") "The controlled release of a peptide from a cell or a tissue.") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0002790") AnnotationAssertion(rdfs:label "peptide secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) +# Class: (regulation of peptide secretion) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that modulates the frequency, rate, or extent of peptide secretion.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002791") +AnnotationAssertion(rdfs:label "regulation of peptide secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of peptide secretion) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that stops, prevents, or reduces the frequency, rate, or extent of peptide secretion.") +AnnotationAssertion( "down regulation of peptide secretion") +AnnotationAssertion( "down-regulation of peptide secretion") +AnnotationAssertion( "downregulation of peptide secretion") +AnnotationAssertion( "inhibition of peptide secretion") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002792") +AnnotationAssertion(rdfs:label "negative regulation of peptide secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of peptide secretion) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that activates or increases the frequency, rate, or extent of peptide secretion.") +AnnotationAssertion( "up regulation of peptide secretion") +AnnotationAssertion( "up-regulation of peptide secretion") +AnnotationAssertion( "upregulation of peptide secretion") +AnnotationAssertion( "activation of peptide secretion") +AnnotationAssertion( "stimulation of peptide secretion") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002793") +AnnotationAssertion(rdfs:label "positive regulation of peptide secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of antimicrobial peptide secretion) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that modulates the frequency, rate, or extent of antimicrobial peptide secretion.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002794") +AnnotationAssertion(rdfs:label "regulation of antimicrobial peptide secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (negative regulation of antimicrobial peptide secretion) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that stops, prevents, or reduces the frequency, rate, or extent of antimicrobial peptide secretion.") +AnnotationAssertion( "down regulation of antimicrobial peptide secretion") +AnnotationAssertion( "down-regulation of antimicrobial peptide secretion") +AnnotationAssertion( "downregulation of antimicrobial peptide secretion") +AnnotationAssertion( "inhibition of antimicrobial peptide secretion") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002795") +AnnotationAssertion(rdfs:label "negative regulation of antimicrobial peptide secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (positive regulation of antimicrobial peptide secretion) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that activates or increases the frequency, rate, or extent of antimicrobial peptide secretion.") +AnnotationAssertion( "up regulation of antimicrobial peptide secretion") +AnnotationAssertion( "up-regulation of antimicrobial peptide secretion") +AnnotationAssertion( "upregulation of antimicrobial peptide secretion") +AnnotationAssertion( "activation of antimicrobial peptide secretion") +AnnotationAssertion( "stimulation of antimicrobial peptide secretion") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002796") +AnnotationAssertion(rdfs:label "positive regulation of antimicrobial peptide secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (regulation of adaptive immune response) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that modulates the frequency, rate, or extent of an adaptive immune response.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002819") +AnnotationAssertion(rdfs:label "regulation of adaptive immune response") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of adaptive immune response) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that stops, prevents, or reduces the frequency, rate, or extent of an adaptive immune response.") +AnnotationAssertion( "down regulation of adaptive immune response") +AnnotationAssertion( "down-regulation of adaptive immune response") +AnnotationAssertion( "downregulation of adaptive immune response") +AnnotationAssertion( "inhibition of adaptive immune response") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002820") +AnnotationAssertion(rdfs:label "negative regulation of adaptive immune response") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of adaptive immune response) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that activates or increases the frequency, rate, or extent of an adaptive immune response.") +AnnotationAssertion( "up regulation of adaptive immune response") +AnnotationAssertion( "up-regulation of adaptive immune response") +AnnotationAssertion( "upregulation of adaptive immune response") +AnnotationAssertion( "activation of adaptive immune response") +AnnotationAssertion( "stimulation of adaptive immune response") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002821") +AnnotationAssertion(rdfs:label "positive regulation of adaptive immune response") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:mtg_sensu") "Any process that modulates the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002822") +AnnotationAssertion(rdfs:label "regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectAllValuesFrom( )) + +# Class: (negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:mtg_sensu") "Any process that stops, prevents, or reduces the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002823") +AnnotationAssertion(rdfs:label "negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:mtg_sensu") "Any process that activates or increases the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002824") +AnnotationAssertion(rdfs:label "positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of type 2 immune response) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that modulates the frequency, rate, or extent of a type 2 immune response.") +AnnotationAssertion(Annotation( "GOC:add") "regulation of T-helper 2 type immune response") +AnnotationAssertion(Annotation( "GOC:add") "regulation of Th2 immune response") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002828") +AnnotationAssertion(rdfs:label "regulation of type 2 immune response") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of type 2 immune response) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that stops, prevents, or reduces the frequency, rate, or extent of a type 2 immune response.") +AnnotationAssertion( "down regulation of type 2 immune response") +AnnotationAssertion( "down-regulation of type 2 immune response") +AnnotationAssertion( "downregulation of type 2 immune response") +AnnotationAssertion( "inhibition of type 2 immune response") +AnnotationAssertion(Annotation( "GOC:add") "negative regulation of T-helper 2 type immune response") +AnnotationAssertion(Annotation( "GOC:add") "negative regulation of Th2 immune response") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002829") +AnnotationAssertion(rdfs:label "negative regulation of type 2 immune response") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of type 2 immune response) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that activates or increases the frequency, rate, or extent of a type 2 immune response.") +AnnotationAssertion( "up regulation of type 2 immune response") +AnnotationAssertion( "up-regulation of type 2 immune response") +AnnotationAssertion( "upregulation of type 2 immune response") +AnnotationAssertion( "activation of type 2 immune response") +AnnotationAssertion(Annotation( "GOC:add") "positive regulation of T-helper 2 type immune response") +AnnotationAssertion(Annotation( "GOC:add") "positive regulation of Th2 immune response") +AnnotationAssertion( "stimulation of type 2 immune response") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002830") +AnnotationAssertion(rdfs:label "positive regulation of type 2 immune response") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of response to biotic stimulus) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that modulates the frequency, rate, or extent of a response to biotic stimulus.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002831") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.") +AnnotationAssertion(rdfs:label "regulation of response to biotic stimulus") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of response to biotic stimulus) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that stops, prevents, or reduces the frequency, rate, or extent of a response to biotic stimulus.") +AnnotationAssertion( "down regulation of response to biotic stimulus") +AnnotationAssertion( "down-regulation of response to biotic stimulus") +AnnotationAssertion( "downregulation of response to biotic stimulus") +AnnotationAssertion( "inhibition of response to biotic stimulus") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002832") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.") +AnnotationAssertion(rdfs:label "negative regulation of response to biotic stimulus") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of response to biotic stimulus) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that activates or increases the frequency, rate, or extent of a response to biotic stimulus.") +AnnotationAssertion( "up regulation of response to biotic stimulus") +AnnotationAssertion( "up-regulation of response to biotic stimulus") +AnnotationAssertion( "upregulation of response to biotic stimulus") +AnnotationAssertion( "activation of response to biotic stimulus") +AnnotationAssertion( "stimulation of response to biotic stimulus") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002833") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.") +AnnotationAssertion(rdfs:label "positive regulation of response to biotic stimulus") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of myeloid leukocyte mediated immunity) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that modulates the frequency, rate, or extent of myeloid leukocyte mediated immunity.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002886") +AnnotationAssertion(rdfs:label "regulation of myeloid leukocyte mediated immunity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of myeloid leukocyte mediated immunity) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid leukocyte mediated immunity.") +AnnotationAssertion( "down regulation of myeloid leukocyte mediated immunity") +AnnotationAssertion( "down-regulation of myeloid leukocyte mediated immunity") +AnnotationAssertion( "downregulation of myeloid leukocyte mediated immunity") +AnnotationAssertion( "inhibition of myeloid leukocyte mediated immunity") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002887") +AnnotationAssertion(rdfs:label "negative regulation of myeloid leukocyte mediated immunity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of myeloid leukocyte mediated immunity) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that activates or increases the frequency, rate, or extent of myeloid leukocyte mediated immunity.") +AnnotationAssertion( "up regulation of myeloid leukocyte mediated immunity") +AnnotationAssertion( "up-regulation of myeloid leukocyte mediated immunity") +AnnotationAssertion( "upregulation of myeloid leukocyte mediated immunity") +AnnotationAssertion( "activation of myeloid leukocyte mediated immunity") +AnnotationAssertion( "stimulation of myeloid leukocyte mediated immunity") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002888") +AnnotationAssertion(rdfs:label "positive regulation of myeloid leukocyte mediated immunity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of immunoglobulin mediated immune response) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that modulates the frequency, rate, or extent of an immunoglobulin mediated immune response.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002889") +AnnotationAssertion(rdfs:label "regulation of immunoglobulin mediated immune response") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of immunoglobulin mediated immune response) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that stops, prevents, or reduces the frequency, rate, or extent of an immunoglobulin mediated immune response.") +AnnotationAssertion( "down regulation of immunoglobulin mediated immune response") +AnnotationAssertion( "down-regulation of immunoglobulin mediated immune response") +AnnotationAssertion( "downregulation of immunoglobulin mediated immune response") +AnnotationAssertion( "inhibition of immunoglobulin mediated immune response") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002890") +AnnotationAssertion(rdfs:label "negative regulation of immunoglobulin mediated immune response") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of immunoglobulin mediated immune response) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that activates or increases the frequency, rate, or extent of an immunoglobulin mediated immune response.") +AnnotationAssertion( "up regulation of immunoglobulin mediated immune response") +AnnotationAssertion( "up-regulation of immunoglobulin mediated immune response") +AnnotationAssertion( "upregulation of immunoglobulin mediated immune response") +AnnotationAssertion( "activation of immunoglobulin mediated immune response") +AnnotationAssertion( "stimulation of immunoglobulin mediated immune response") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002891") +AnnotationAssertion(rdfs:label "positive regulation of immunoglobulin mediated immune response") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (mature B cell apoptotic process) + +AnnotationAssertion(Annotation( "CL:0000785") Annotation( "GOC:add") Annotation( "GOC:mtg_apoptosis") Annotation( "ISBN:0781735149") "Any apoptotic process in a B cell that is mature, having left the bone marrow.") +AnnotationAssertion( "apoptosis of mature B cells") +AnnotationAssertion( "apoptosis of mature B lymphocytes") +AnnotationAssertion( "apoptosis of mature B-cells") +AnnotationAssertion( "apoptosis of mature B-lymphocytes") +AnnotationAssertion( "mature B cell programmed cell death by apoptosis") +AnnotationAssertion( "mature B lymphocyte apoptosis") +AnnotationAssertion( "mature B lymphocyte programmed cell death by apoptosis") +AnnotationAssertion( "mature B-cell apoptosis") +AnnotationAssertion( "mature B-cell programmed cell death by apoptosis") +AnnotationAssertion( "mature B-lymphocyte apoptosis") +AnnotationAssertion( "mature B-lymphocyte programmed cell death by apoptosis") +AnnotationAssertion( "programmed cell death of mature B cells by apoptosis") +AnnotationAssertion( "programmed cell death of mature B lymphocytes by apoptosis") +AnnotationAssertion( "programmed cell death of mature B-cells by apoptosis") +AnnotationAssertion( "programmed cell death of mature B-lymphocytes by apoptosis") +AnnotationAssertion( "programmed cell death, mature B cells") +AnnotationAssertion( "programmed cell death, mature B lymphocytes") +AnnotationAssertion( "programmed cell death, mature B-cells") +AnnotationAssertion( "programmed cell death, mature B-lymphocytes") +AnnotationAssertion( "mature B cell apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002901") +AnnotationAssertion(rdfs:label "mature B cell apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (regulation of B cell apoptotic process) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:mtg_apoptosis") "Any process that modulates the frequency, rate, or extent of B cell apoptotic process.") +AnnotationAssertion( "regulation of B cell apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002902") +AnnotationAssertion(rdfs:label "regulation of B cell apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of B cell apoptotic process) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:mtg_apoptosis") "Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell apoptotic process.") +AnnotationAssertion( "down regulation of B cell apoptosis") +AnnotationAssertion( "down-regulation of B cell apoptosis") +AnnotationAssertion( "downregulation of B cell apoptosis") +AnnotationAssertion( "inhibition of B cell apoptosis") +AnnotationAssertion( "negative regulation of B cell apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002903") +AnnotationAssertion(rdfs:label "negative regulation of B cell apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of B cell apoptotic process) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:mtg_apoptosis") "Any process that activates or increases the frequency, rate, or extent of B cell apoptotic process.") +AnnotationAssertion( "up regulation of B cell apoptosis") +AnnotationAssertion( "up-regulation of B cell apoptosis") +AnnotationAssertion( "upregulation of B cell apoptosis") +AnnotationAssertion( "activation of B cell apoptosis") +AnnotationAssertion( "positive regulation of B cell apoptosis") +AnnotationAssertion( "stimulation of B cell apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002904") +AnnotationAssertion(rdfs:label "positive regulation of B cell apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of mature B cell apoptotic process) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:mtg_apoptosis") "Any process that modulates the frequency, rate, or extent of mature B cell apoptotic process.") +AnnotationAssertion( "regulation of mature B cell apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002905") +AnnotationAssertion(rdfs:label "regulation of mature B cell apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (negative regulation of mature B cell apoptotic process) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:mtg_apoptosis") "Any process that stops, prevents, or reduces the frequency, rate, or extent of mature B cell apoptotic process.") +AnnotationAssertion( "down regulation of mature B cell apoptosis") +AnnotationAssertion( "down-regulation of mature B cell apoptosis") +AnnotationAssertion( "downregulation of mature B cell apoptosis") +AnnotationAssertion( "inhibition of mature B cell apoptosis") +AnnotationAssertion( "negative regulation of mature B cell apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002906") +AnnotationAssertion(rdfs:label "negative regulation of mature B cell apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of mature B cell apoptotic process) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:mtg_apoptosis") "Any process that activates or increases the frequency, rate, or extent of mature B cell apoptotic process.") +AnnotationAssertion( "up regulation of mature B cell apoptosis") +AnnotationAssertion( "up-regulation of mature B cell apoptosis") +AnnotationAssertion( "upregulation of mature B cell apoptosis") +AnnotationAssertion( "activation of mature B cell apoptosis") +AnnotationAssertion( "positive regulation of mature B cell apoptosis") +AnnotationAssertion( "stimulation of mature B cell apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002907") +AnnotationAssertion(rdfs:label "positive regulation of mature B cell apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (regulation of humoral immune response) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that modulates the frequency, rate, or extent of a humoral immune response.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002920") +AnnotationAssertion(rdfs:label "regulation of humoral immune response") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of humoral immune response) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that stops, prevents, or reduces the frequency, rate, or extent of a humoral immune response.") +AnnotationAssertion( "down regulation of humoral immune response") +AnnotationAssertion( "down-regulation of humoral immune response") +AnnotationAssertion( "downregulation of humoral immune response") +AnnotationAssertion( "inhibition of humoral immune response") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002921") +AnnotationAssertion(rdfs:label "negative regulation of humoral immune response") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of humoral immune response) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that activates or increases the frequency, rate, or extent of a humoral immune response.") +AnnotationAssertion( "up regulation of humoral immune response") +AnnotationAssertion( "up-regulation of humoral immune response") +AnnotationAssertion( "upregulation of humoral immune response") +AnnotationAssertion( "activation of humoral immune response") +AnnotationAssertion( "stimulation of humoral immune response") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002922") +AnnotationAssertion(rdfs:label "positive regulation of humoral immune response") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (trabecular meshwork development) + +AnnotationAssertion(Annotation( "PMID:20568247") "The progression of the trabecular meshwork over time, from its formation to the mature structure. The trabecular meshwork is a fenestrated endothelial-like tissue situated at the intersection of the cornea and the iris. The trabecular meshwork provides drainage for the aqueous humor.") +AnnotationAssertion( "hjd") +AnnotationAssertion( "2012-04-19T04:50:06Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002930") +AnnotationAssertion(rdfs:label "trabecular meshwork development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (tendon sheath development) + +AnnotationAssertion(Annotation( "PMID:20696843") "The process whose specific outcome is the progression of a tendon sheath over time, from its formation to the mature structure. A tendon sheath is a layer of membrane around a tendon. It permits the tendon to move.") +AnnotationAssertion( "hjd") +AnnotationAssertion( "2012-04-23T02:11:22Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002932") +AnnotationAssertion(rdfs:label "tendon sheath development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (synoviocyte proliferation) + +AnnotationAssertion(Annotation( "PMID:10770586") Annotation( "PMID:9546370") "The multiplication or reproduction of type B synoviocytes by cell division, resulting in the expansion of their population. A type B synoviocyte is a fibroblast-like cell found in synovial tissues.") +AnnotationAssertion( "hjd") +AnnotationAssertion( "2012-11-16T14:25:45Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0002941") +AnnotationAssertion(rdfs:label "synoviocyte proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regionalization) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:isa_complete") "The pattern specification process that results in the subdivision of an axis or axes in space to define an area or volume in which specific patterns of cell differentiation will take place or in which cells interpret a specific environment.") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") "pattern formation") +AnnotationAssertion( "GO:0003002") +AnnotationAssertion(rdfs:label "regionalization") +SubClassOf( ) + # Class: (developmental process involved in reproduction) AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:isa_complete") "A developmental process in which a progressive change in the state of some part of an organism, germline or somatic, specifically contributes to its ability to form offspring.") @@ -28281,9 +49976,21 @@ AnnotationAssertion( "GOC:dph") Annotation( "GOC:tb") "reproductive developmental process") AnnotationAssertion( "GO:0003006") AnnotationAssertion(rdfs:label "developmental process involved in reproduction") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) +# Class: (heart morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:isa_complete") "The developmental process in which the heart is generated and organized. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "cardiac morphogenesis") +AnnotationAssertion( "GO:0003007") +AnnotationAssertion(rdfs:label "heart morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (system process) AnnotationAssertion(Annotation( "GOC:mtg_cardio") "A multicellular organismal process carried out by any of the organs or tissues in an organ system. An organ system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a biological objective.") @@ -28293,6 +50000,16 @@ AnnotationAssertion( "system process") SubClassOf( ) +# Class: (skeletal muscle contraction) + +AnnotationAssertion(Annotation( "GOC:mtg_cardio") Annotation( "GOC:mtg_muscle") "A process in which force is generated within skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. In the skeletal muscle, the muscle contraction takes advantage of an ordered sarcomeric structure and in most cases it is under voluntary control.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003009") +AnnotationAssertion(rdfs:label "skeletal muscle contraction") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (muscle system process) AnnotationAssertion(Annotation( "GOC:mtg_cardio") "A organ system process carried out at the level of a muscle. Muscle tissue is composed of contractile cells or fibers.") @@ -28355,6 +50072,15 @@ AnnotationAssertion( "lymph circulation") SubClassOf( ) +# Class: (vascular process in circulatory system) + +AnnotationAssertion(Annotation( "GOC:mtg_cardio") "A circulatory process that occurs at the level of the vasculature.") +AnnotationAssertion( "vasculature process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003018") +AnnotationAssertion(rdfs:label "vascular process in circulatory system") +SubClassOf( ) + # Class: (central nervous system control of baroreceptor feedback) AnnotationAssertion(Annotation( "GOC:mtg_cardio") Annotation( "ISBN:0323031951") "The neurological process in which nerve impulses arising in the aorta or the carotid sinuses travel to the medulla and reach the nucleus of tractus solaris.") @@ -28458,6 +50184,7 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:0003071") AnnotationAssertion(rdfs:label "renal system process involved in regulation of systemic arterial blood pressure") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) # Class: (regulation of systemic arterial blood pressure) @@ -28493,6 +50220,7 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:0003093") AnnotationAssertion(rdfs:label "regulation of glomerular filtration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) @@ -28502,19 +50230,2193 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:0003094") AnnotationAssertion(rdfs:label "glomerular filtration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (renal sodium ion transport) + +AnnotationAssertion(Annotation( "GOC:mtg_cardio") "The directed movement of sodium ions (Na+) by the renal system.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003096") +AnnotationAssertion(rdfs:label "renal sodium ion transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + # Class: (renal water transport) AnnotationAssertion(Annotation( "GOC:mtg_cardio") "The directed movement of water (H2O) by the renal system.") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0003097") AnnotationAssertion(rdfs:label "renal water transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (positive regulation of glomerular filtration) + +AnnotationAssertion(Annotation( "GOC:mtg_cardio") "Any process that activates or increases the frequency, rate or extent of glomerular filtration. Glomerular filtration is the processs whereby blood is filtered by the glomerulus into the renal tubule.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003104") +AnnotationAssertion(rdfs:label "positive regulation of glomerular filtration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of glomerular filtration) + +AnnotationAssertion(Annotation( "GOC:mtg_cardio") "Any process that stops, prevents, or reduces the frequency, rate or extent of glomerular filtration. Glomerular filtration is the processs whereby blood is filtered by the glomerulus into the renal tubule.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003105") +AnnotationAssertion(rdfs:label "negative regulation of glomerular filtration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (endodermal-mesodermal cell signaling) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "Any process that mediates the transfer of information from endodermal cells to mesodermal cells.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2009-09-22T03:10:29Z") +AnnotationAssertion(Annotation( "GOC:mah") "endodermal-mesodermal cell signalling") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003133") +AnnotationAssertion(rdfs:label "endodermal-mesodermal cell signaling") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (cardiogenic plate morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which the anatomical structures of the cardiogenic plate are generated and organized. The cardiogenic plate is the first recognizable structure derived from the heart field.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2009-09-22T04:12:18Z") +AnnotationAssertion(Annotation( "GOC:mtg_heart") "cardiac crescent morphogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003142") +AnnotationAssertion(rdfs:label "cardiogenic plate morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (embryonic heart tube morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which the anatomical structures of the embryonic heart tube are generated and organized. The embryonic heart tube is an epithelial tube that will give rise to the mature heart.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2009-09-22T04:21:17Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003143") +AnnotationAssertion(rdfs:label "embryonic heart tube morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (embryonic heart tube formation) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process that gives rise to the embryonic heart tube. This process pertains to the initial formation of a structure from unspecified parts. The embryonic heart tube is an epithelial tube that will give rise to the mature heart.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2009-09-22T04:22:34Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003144") +AnnotationAssertion(rdfs:label "embryonic heart tube formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (embryonic heart tube formation via epithelial folding) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process that gives rise to the embryonic heart tube by the cells of the heart field along a linear axis.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2009-09-22T04:26:03Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003145") +AnnotationAssertion(rdfs:label "embryonic heart tube formation via epithelial folding") +SubClassOf( ) + +# Class: (neural crest cell migration involved in heart formation) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The characteristic movement of a cell from the dorsal ridge of the neural tube towards the heart and that contributes to heart formation.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2009-09-22T04:29:55Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003147") +AnnotationAssertion(rdfs:label "neural crest cell migration involved in heart formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (outflow tract septum morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which the anatomical structures of the outflow tract septum are generated and organized. The outflow tract septum is a partition in the outflow tract.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2009-09-22T07:51:01Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003148") +AnnotationAssertion(rdfs:label "outflow tract septum morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (membranous septum morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which the membranous septum is generated and organized. The membranous septum is the upper part of ventricular septum.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2009-09-22T07:51:41Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003149") +AnnotationAssertion(rdfs:label "membranous septum morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (muscular septum morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which the muscular septum is generated and organized. The muscular septum is the lower part of the ventricular septum.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2009-09-22T07:53:28Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003150") +AnnotationAssertion(rdfs:label "muscular septum morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (outflow tract morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") Annotation( "UBERON:0004145") "The process in which the anatomical structures of the outflow tract are generated and organized. The outflow tract is the portion of the heart through which blood flows into the arteries.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2009-09-22T07:59:24Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003151") +AnnotationAssertion(rdfs:label "outflow tract morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (morphogenesis of an epithelial fold involved in embryonic heart tube formation) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The morphogenetic process in which an epithelial sheet bends along a linear axis, contributing to embryonic heart tube formation.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2009-09-23T10:10:24Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003152") +AnnotationAssertion(rdfs:label "morphogenesis of an epithelial fold involved in embryonic heart tube formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (regulation of animal organ formation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_heart") Annotation( "GOC:tb") "Any process that modulates the rate, frequency or extent of animal organ formation. Organ formation is the process pertaining to the initial formation of an organ from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure, such as inductive events, and ends when the structural rudiment of the organ is recognizable, such as a condensation of mesenchymal cells into the organ rudiment.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2009-09-30T11:21:09Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003156") +AnnotationAssertion(rdfs:label "regulation of animal organ formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (endocardium development) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process whose specific outcome is the progression of the endocardium over time, from its formation to the mature structure. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-01T12:42:27Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003157") +AnnotationAssertion(rdfs:label "endocardium development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (endothelium development) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process whose specific outcome is the progression of an endothelium over time, from its formation to the mature structure. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-01T12:50:57Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003158") +AnnotationAssertion(rdfs:label "endothelium development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (morphogenesis of an endothelium) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which the anatomical structure of an endothelium is generated and organized. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-01T01:34:06Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003159") +AnnotationAssertion(rdfs:label "morphogenesis of an endothelium") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (endocardium morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which the anatomical structure of the endocardium is generated and organized. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-01T01:37:26Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003160") +AnnotationAssertion(rdfs:label "endocardium morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cardiac conduction system development) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process whose specific outcome is the progression of the cardiac conduction system over time, from its formation to the mature structure. The cardiac conduction system consists of specialized cardiomyocytes that regulate the frequency of heart beat.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-01T01:57:16Z") +AnnotationAssertion(Annotation( "GOC:mtg_heart") "cardiac impulse conducting system development") +AnnotationAssertion(Annotation( "GOC:mtg_heart") "heart conduction system development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003161") +AnnotationAssertion(rdfs:label "cardiac conduction system development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (atrioventricular node development) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process whose specific outcome is the progression of the atrioventricular (AV) node over time, from its formation to the mature structure. The AV node is part of the cardiac conduction system that controls the timing of ventricle contraction by receiving electrical signals from the sinoatrial (SA) node and relaying them to the His-Purkinje system.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-01T02:05:13Z") +AnnotationAssertion(Annotation( "GOC:mtg_heart") "AV node development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003162") +AnnotationAssertion(rdfs:label "atrioventricular node development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (sinoatrial node development) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process whose specific outcome is the progression of the sinoatrial (SA) node over time, from its formation to the mature structure. The SA node is part of the cardiac conduction system that controls the timing of heart muscle contraction. It relays electrical signals to the AV node.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-01T02:06:09Z") +AnnotationAssertion(Annotation( "GOC:mtg_heart") "SA node development") +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mtg_cardiac_conduct_nov11") "SAN development") +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mtg_cardiac_conduct_nov11") "sinus node development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003163") +AnnotationAssertion(rdfs:label "sinoatrial node development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (His-Purkinje system development) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process whose specific outcome is the progression of the His-Purkinje system over time, from its formation to the mature structure. The His-Purkinje system receives signals from the AV node and is composed of the fibers that regulate cardiac muscle contraction in the ventricles.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-01T02:07:12Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003164") +AnnotationAssertion(rdfs:label "His-Purkinje system development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (Purkinje myocyte development) + +AnnotationAssertion(Annotation( "GOC:mtg_cardiac_conduct_nov11") Annotation( "GOC:mtg_heart") "The process whose specific outcome is the progression of a Purkinje myocyte over time, from its formation to the mature structure. The Purkinje myocyte (also known as cardiac Purkinje fiber) is part of the cardiac conduction system that receives signals from the bundle of His and innervates the ventricular cardiac muscle.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-01T02:07:50Z") +AnnotationAssertion( "cardiac Purkinje fiber development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003165") +AnnotationAssertion(rdfs:label "Purkinje myocyte development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (bundle of His development) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process whose specific outcome is the progression of the bundle of His over time, from its formation to the mature structure. The bundle of His is part of the His-Purkinje system that transmits signals from the AV node to the cardiac Purkinje fibers.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-01T02:08:43Z") +AnnotationAssertion(Annotation( "GOC:mtg_heart") "atrioventricular bundle development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003166") +AnnotationAssertion(rdfs:label "bundle of His development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (atrioventricular bundle cell differentiation) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell of the atrioventricular bundle. These cells are specialized cardiomyocytes that transmit signals from the AV node to the cardiac Purkinje fibers.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-01T02:48:23Z") +AnnotationAssertion(Annotation( "GOC:mtg_heart") "AV bundle cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003167") +AnnotationAssertion(rdfs:label "atrioventricular bundle cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (Purkinje myocyte differentiation) + +AnnotationAssertion(Annotation( "GOC:mtg_cardiac_conduct_nov11") Annotation( "GOC:mtg_heart") "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a Purkinje myocyte (also known as cardiac Purkinje fiber cell). These cells are specialized cardiomyocytes that receive signals from the bundle of His and innervate the ventricular cardiac muscle.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-01T02:49:54Z") +AnnotationAssertion( "cardiac Purkinje fiber cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003168") +AnnotationAssertion(rdfs:label "Purkinje myocyte differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (coronary vein morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which the anatomical structures of veins of the heart are generated and organized.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-08T10:45:41Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003169") +AnnotationAssertion(rdfs:label "coronary vein morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (heart valve development) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The progression of a heart valve over time, from its formation to the mature structure. A heart valve is a structure that restricts the flow of blood to different regions of the heart and forms from an endocardial cushion.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-08T10:50:09Z") +AnnotationAssertion(Annotation( "GOC:mtg_heart") "cardiac valve development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003170") +AnnotationAssertion(rdfs:label "heart valve development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (atrioventricular valve development) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The progression of the atrioventricular valve over time, from its formation to the mature structure.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-08T11:14:21Z") +AnnotationAssertion(Annotation( "GOC:mah") "AV valve development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003171") +AnnotationAssertion(rdfs:label "atrioventricular valve development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (sinoatrial valve development) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The progression of the sinoatrial valve over time, from its formation to the mature structure.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-08T11:15:39Z") +AnnotationAssertion(Annotation( "GOC:mah") "SA valve development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003172") +AnnotationAssertion(rdfs:label "sinoatrial valve development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (ventriculo bulbo valve development) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The progression of the ventriculo bulbo valve over time, from its formation to the mature structure.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-08T11:16:25Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003173") +AnnotationAssertion(rdfs:label "ventriculo bulbo valve development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (mitral valve development) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The progression of the mitral valve over time, from its formation to the mature structure.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-08T11:17:22Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003174") +AnnotationAssertion(rdfs:label "mitral valve development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (tricuspid valve development) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The progression of the tricuspid valve over time, from its formation to the mature structure.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-08T11:18:12Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003175") +AnnotationAssertion(rdfs:label "tricuspid valve development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (aortic valve development) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The progression of the aortic valve over time, from its formation to the mature structure.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-08T11:18:55Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003176") +AnnotationAssertion(rdfs:label "aortic valve development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (pulmonary valve development) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The progression of the pulmonary valve over time, from its formation to the mature structure.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-08T11:19:44Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003177") +AnnotationAssertion(rdfs:label "pulmonary valve development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (coronary sinus valve development) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The progression of the valve of the coronary sinus over time, from its formation to the mature structure.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-08T11:21:43Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003178") +AnnotationAssertion(rdfs:label "coronary sinus valve development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (heart valve morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which the structure of a heart valve is generated and organized.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-08T11:23:48Z") +AnnotationAssertion(Annotation( "GOC:vk") Annotation( "GOC:yaf") "heart valve remodeling") +AnnotationAssertion(Annotation( "GOC:vk") Annotation( "GOC:yaf") "heart valve remodelling") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003179") +AnnotationAssertion(rdfs:label "heart valve morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (aortic valve morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which the structure of the aortic valve is generated and organized.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-08T11:29:42Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003180") +AnnotationAssertion(rdfs:label "aortic valve morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (atrioventricular valve morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which the structure of the atrioventricular valve is generated and organized.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-08T11:31:59Z") +AnnotationAssertion(Annotation( "GOC:mah") "AV valve morphogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003181") +AnnotationAssertion(rdfs:label "atrioventricular valve morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (coronary sinus valve morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which the structure of the coronary sinus valve is generated and organized.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-08T11:33:31Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003182") +AnnotationAssertion(rdfs:label "coronary sinus valve morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (mitral valve morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which the structure of the mitral valve is generated and organized.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-08T12:02:01Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003183") +AnnotationAssertion(rdfs:label "mitral valve morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (pulmonary valve morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which the structure of the pulmonary valve is generated and organized.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-08T12:03:35Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003184") +AnnotationAssertion(rdfs:label "pulmonary valve morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (sinoatrial valve morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which the structure of the sinoatrial valve is generated and organized.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-08T12:04:52Z") +AnnotationAssertion(Annotation( "GOC:mah") "SA valve morphogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003185") +AnnotationAssertion(rdfs:label "sinoatrial valve morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (tricuspid valve morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which the structure of the tricuspid valve is generated and organized.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-08T12:05:45Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003186") +AnnotationAssertion(rdfs:label "tricuspid valve morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (ventriculo bulbo valve morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which the structure of the ventriculo bulbo valve is generated and organized.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-08T12:07:00Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003187") +AnnotationAssertion(rdfs:label "ventriculo bulbo valve morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (heart valve formation) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The developmental process pertaining to the initial formation of a heart valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-08T12:20:15Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003188") +AnnotationAssertion(rdfs:label "heart valve formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (aortic valve formation) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The developmental process pertaining to the initial formation of the aortic valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-08T01:05:44Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003189") +AnnotationAssertion(rdfs:label "aortic valve formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (atrioventricular valve formation) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The developmental process pertaining to the initial formation of the atrioventricular valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-08T01:07:28Z") +AnnotationAssertion(Annotation( "GOC:mah") "AV valve formation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003190") +AnnotationAssertion(rdfs:label "atrioventricular valve formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (coronary sinus valve formation) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The developmental process pertaining to the initial formation of the coronary sinus valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-08T01:09:04Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003191") +AnnotationAssertion(rdfs:label "coronary sinus valve formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (mitral valve formation) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The developmental process pertaining to the initial formation of the mitral valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-08T01:10:19Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003192") +AnnotationAssertion(rdfs:label "mitral valve formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (pulmonary valve formation) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The developmental process pertaining to the initial formation of the pulmonary valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-08T01:11:20Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003193") +AnnotationAssertion(rdfs:label "pulmonary valve formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (sinoatrial valve formation) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The developmental process pertaining to the initial formation of the sinoatrial valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-08T01:12:45Z") +AnnotationAssertion(Annotation( "GOC:mah") "SA valve formation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003194") +AnnotationAssertion(rdfs:label "sinoatrial valve formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (tricuspid valve formation) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The developmental process pertaining to the initial formation of the tricuspid valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-08T01:14:40Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003195") +AnnotationAssertion(rdfs:label "tricuspid valve formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (ventriculo bulbo valve formation) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The developmental process pertaining to the initial formation of the ventriculo bulbo valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-08T01:16:02Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003196") +AnnotationAssertion(rdfs:label "ventriculo bulbo valve formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (endocardial cushion development) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The progression of a cardiac cushion over time, from its initial formation to the mature structure. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-08T01:17:43Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003197") +AnnotationAssertion(rdfs:label "endocardial cushion development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (endocardial cushion morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which the anatomical structure of the endocardial cushion is generated and organized. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-08T01:43:22Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003203") +AnnotationAssertion(rdfs:label "endocardial cushion morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cardiac skeleton development) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The progression of the cardiac skeleton over time, from its formation to the mature structure. The cardiac skeleton is a specialized extracellular matrix that separates the atria from the ventricles and provides physical support for the heart.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-13T09:05:04Z") +AnnotationAssertion(Annotation( "GOC:mtg_heart") "heart fibrous skeleton development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003204") +AnnotationAssertion(rdfs:label "cardiac skeleton development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cardiac chamber development) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The progression of a cardiac chamber over time, from its formation to the mature structure. A cardiac chamber is an enclosed cavity within the heart.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-13T09:11:18Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003205") +AnnotationAssertion(rdfs:label "cardiac chamber development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cardiac chamber morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which a cardiac chamber is generated and organized. A cardiac chamber is an enclosed cavity within the heart.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-13T09:14:51Z") +AnnotationAssertion(Annotation( "GOC:mtg_heart") "heart chamber morphogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003206") +AnnotationAssertion(rdfs:label "cardiac chamber morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cardiac chamber formation) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The developmental process pertaining to the initial formation of a cardiac chamber from unspecified parts. A cardiac chamber is an enclosed cavity within the heart.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-13T09:29:13Z") +AnnotationAssertion(Annotation( "GOC:mtg_heart") "heart chamber formation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003207") +AnnotationAssertion(rdfs:label "cardiac chamber formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cardiac ventricle morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which the cardiac ventricle is generated and organized. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-13T09:38:44Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003208") +AnnotationAssertion(rdfs:label "cardiac ventricle morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cardiac atrium morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which the cardiac atrium is generated and organized. A cardiac atrium receives blood from a vein and pumps it to a cardiac ventricle.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-13T09:39:44Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003209") +AnnotationAssertion(rdfs:label "cardiac atrium morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cardiac atrium formation) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The developmental process pertaining to the initial formation of a cardiac atrium from unspecified parts. A cardiac atrium receives blood from a vein and pumps it to a cardiac ventricle.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-13T09:44:25Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003210") +AnnotationAssertion(rdfs:label "cardiac atrium formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cardiac ventricle formation) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The developmental process pertaining to the initial formation of a cardiac ventricle from unspecified parts. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-13T09:46:27Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003211") +AnnotationAssertion(rdfs:label "cardiac ventricle formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cardiac left atrium morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which the left cardiac atrium is generated and organized.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-13T09:48:16Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003212") +AnnotationAssertion(rdfs:label "cardiac left atrium morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (cardiac right atrium morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which the right cardiac atrium is generated and organized.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-13T09:49:03Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003213") +AnnotationAssertion(rdfs:label "cardiac right atrium morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (cardiac left ventricle morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which the left cardiac ventricle is generated and organized.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-13T09:50:08Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003214") +AnnotationAssertion(rdfs:label "cardiac left ventricle morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (cardiac right ventricle morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which the right cardiac ventricle is generated and organized.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-13T09:50:57Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003215") +AnnotationAssertion(rdfs:label "cardiac right ventricle morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (cardiac left atrium formation) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The developmental process pertaining to the initial formation of a left cardiac atrium from unspecified parts.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-13T09:52:31Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003216") +AnnotationAssertion(rdfs:label "cardiac left atrium formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cardiac right atrium formation) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The developmental process pertaining to the initial formation of a cardiac right atrium from unspecified parts.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-13T09:53:12Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003217") +AnnotationAssertion(rdfs:label "cardiac right atrium formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cardiac left ventricle formation) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The developmental process pertaining to the initial formation of a left cardiac ventricle from unspecified parts.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-13T09:54:33Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003218") +AnnotationAssertion(rdfs:label "cardiac left ventricle formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cardiac right ventricle formation) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The developmental process pertaining to the initial formation of a right cardiac ventricle from unspecified parts.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-13T09:55:38Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003219") +AnnotationAssertion(rdfs:label "cardiac right ventricle formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (left ventricular cardiac muscle tissue morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which the anatomical structures of left cardiac ventricle muscle are generated and organized.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-13T10:18:05Z") +AnnotationAssertion(Annotation( "GOC:mtg_heart") "left ventricular myocardium morphogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003220") +AnnotationAssertion(rdfs:label "left ventricular cardiac muscle tissue morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (right ventricular cardiac muscle tissue morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which the anatomical structures of the right cardiac ventricle muscle are generated and organized.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-13T10:26:33Z") +AnnotationAssertion(Annotation( "GOC:mtg_heart") "right ventricle myocardium morphogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003221") +AnnotationAssertion(rdfs:label "right ventricular cardiac muscle tissue morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (ventricular trabecula myocardium morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which the anatomical structures of the trabecular cardiac ventricle muscle are generated and organized.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-13T10:33:00Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") "trabecula carnea morphogenesis") +AnnotationAssertion( "GO:0003222") +AnnotationAssertion(rdfs:label "ventricular trabecula myocardium morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (ventricular compact myocardium morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which the anatomical structures of the compact cardiac ventricle muscle are generated and organized.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-13T10:34:21Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003223") +AnnotationAssertion(rdfs:label "ventricular compact myocardium morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (left ventricular compact myocardium morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which the anatomical structures of cardiac left ventricular compact myocardium are generated and organized.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-13T10:43:36Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003224") +AnnotationAssertion(rdfs:label "left ventricular compact myocardium morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (left ventricular trabecular myocardium morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which the anatomical structures of cardiac left ventricular trabecular myocardium are generated and organized.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-13T10:45:09Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003225") +AnnotationAssertion(rdfs:label "left ventricular trabecular myocardium morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (right ventricular compact myocardium morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which the anatomical structures of the right ventricular compact myocardium are generated and organized.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-13T10:48:42Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003226") +AnnotationAssertion(rdfs:label "right ventricular compact myocardium morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (right ventricular trabecular myocardium morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which the anatomical structures of the right ventricular myocardium are generated and organized.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-13T10:50:59Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003227") +AnnotationAssertion(rdfs:label "right ventricular trabecular myocardium morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (atrial cardiac muscle tissue development) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process whose specific outcome is the progression of cardiac muscle of the atrium over time, from its formation to the mature structure.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/22614"^^xsd:anyURI) +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-13T10:53:18Z") +AnnotationAssertion(Annotation( "GOC:mtg_heart") "atrial myocardium development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003228") +AnnotationAssertion(rdfs:label "atrial cardiac muscle tissue development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (ventricular cardiac muscle tissue development) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process whose specific outcome is the progression of ventricular cardiac muscle over time, from its formation to the mature structure.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-13T10:56:01Z") +AnnotationAssertion(Annotation( "GOC:mtg_heart") "ventricular myocardium development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003229") +AnnotationAssertion(rdfs:label "ventricular cardiac muscle tissue development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (cardiac atrium development) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process whose specific outcome is the progression of a cardiac atrium over time, from its formation to the mature structure. A cardiac atrium receives blood from a vein and pumps it to a cardiac ventricle.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-13T11:02:07Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003230") +AnnotationAssertion(rdfs:label "cardiac atrium development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (cardiac ventricle development) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process whose specific outcome is the progression of a cardiac ventricle over time, from its formation to the mature structure. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-13T11:03:16Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003231") +AnnotationAssertion(rdfs:label "cardiac ventricle development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (bulbus arteriosus development) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process whose specific outcome is the progression of the bulbus arteriosus over time, from its formation to the mature structure. The bulbus arteriosus is an elastic heart chamber.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-13T11:05:36Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003232") +AnnotationAssertion(rdfs:label "bulbus arteriosus development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (bulbus arteriosus morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which the bulbus arteriosus is generated and organized. The bulbus arteriosus is an elastic cardiac chamber.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-13T11:07:30Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003233") +AnnotationAssertion(rdfs:label "bulbus arteriosus morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (bulbus arteriosus formation) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The developmental process pertaining to the initial formation of the bulbus arteriosus from unspecified parts. The bulbus arteriosus is an elastic chamber of the heart.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-13T11:10:02Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003234") +AnnotationAssertion(rdfs:label "bulbus arteriosus formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (sinus venosus development) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The progression of the sinus venosus over time, from its formation to the mature structure. The sinus venosus is a heart chamber attached to the atrium on the venous side of the embryonic heart.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-13T11:12:34Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003235") +AnnotationAssertion(rdfs:label "sinus venosus development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (sinus venosus morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which the sinus venosus is generated and organized. The sinus venosus is a heart chamber attached to the atrium on the venous side of the embryonic heart.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-13T11:16:52Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003236") +AnnotationAssertion(rdfs:label "sinus venosus morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (sinus venosus formation) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The developmental process pertaining to the initial formation of the sinus venosus from unspecified parts. The sinus venosus is a heart chamber attached to the atrium on the venous side of the embryonic heart.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-13T11:18:34Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003237") +AnnotationAssertion(rdfs:label "sinus venosus formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (conus arteriosus development) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The progression of the conus arteriosus over time, from its formation to the mature structure. The conus arteriosus is a valved chamber with thick muscular walls stemming from the ventricle and connecting to the pulmonary trunk.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-13T11:20:57Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003238") +AnnotationAssertion(rdfs:label "conus arteriosus development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (conus arteriosus morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which the conus arteriosus is generated and organized. The conus arteriosus is a valved chamber with thick muscular walls stemming from the ventricle and connecting to the pulmonary trunk.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-13T11:25:04Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003239") +AnnotationAssertion(rdfs:label "conus arteriosus morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (conus arteriosus formation) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The developmental process pertaining to the initial formation of the conus arteriosus from unspecified parts. The conus arteriosus is a valved chamber with thick muscular walls stemming from the ventricle and connecting to the pulmonary trunk.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-13T11:25:47Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003240") +AnnotationAssertion(rdfs:label "conus arteriosus formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (growth involved in heart morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "Developmental growth that contributes to the shaping of the heart.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-13T11:28:46Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003241") +AnnotationAssertion(rdfs:label "growth involved in heart morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cardiac muscle tissue growth involved in heart morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The developmental growth of cardiac muscle tissue that contributes to the shaping of the heart.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-13T11:44:21Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003245") +AnnotationAssertion(rdfs:label "cardiac muscle tissue growth involved in heart morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (heart capillary growth) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The increase in heart capillaries that accompanies physiological hypertrophy of cardiac muscle.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-13T11:53:12Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003248") +AnnotationAssertion(rdfs:label "heart capillary growth") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cell proliferation involved in heart valve morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The multiplication or reproduction of cells that contributes to the shaping of a heart valve.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-13T01:59:19Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003249") +AnnotationAssertion(rdfs:label "cell proliferation involved in heart valve morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of cell proliferation involved in heart valve morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "Any process that modulates the rate, frequency or extent of cell proliferation that contributes to the shaping of a heart valve.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-13T02:03:42Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003250") +AnnotationAssertion(rdfs:label "regulation of cell proliferation involved in heart valve morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of cell proliferation involved in heart valve morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "Any process that increases the rate, frequency or extent of cell proliferation that contributes to the shaping of a heart valve.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-13T02:07:20Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003251") +AnnotationAssertion(rdfs:label "positive regulation of cell proliferation involved in heart valve morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of cell proliferation involved in heart valve morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "Any process that decreases the rate, frequency or extent of cell proliferation that contributes to the shaping of a heart valve.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-13T02:10:39Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003252") +AnnotationAssertion(rdfs:label "negative regulation of cell proliferation involved in heart valve morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (cardiac neural crest cell migration involved in outflow tract morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The orderly movement of a neural crest cell from one site to another that will contribute to the morphogenesis of the outflow tract.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-13T02:14:16Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003253") +AnnotationAssertion(rdfs:label "cardiac neural crest cell migration involved in outflow tract morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cardioblast migration) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The orderly movement of a cardiac progenitor cell to form the heart field. Cardiac progenitor cells are non-terminally differentiated, mesoderm-derived cells that are committed to differentiate into cells of the heart. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-15T01:52:25Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003260") +AnnotationAssertion(rdfs:label "cardioblast migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (endocardial cushion formation) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") Annotation( "PMID:15797462") "The developmental process pertaining to the initial formation of an endocardial cushion. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-20T08:53:19Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003272") +AnnotationAssertion(rdfs:label "endocardial cushion formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cell migration involved in endocardial cushion formation) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The orderly movement of a cell from one site to another that will contribute to the formation of an endocardial cushion. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-20T09:08:44Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003273") +AnnotationAssertion(rdfs:label "cell migration involved in endocardial cushion formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (apoptotic process involved in outflow tract morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:mtg_heart") "Any apoptotic process that contributes to the shaping of the outflow tract. The outflow tract is the portion of the heart through which blood flows into the arteries.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-20T09:30:01Z") +AnnotationAssertion( "apoptosis involved in outflow tract morphogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003275") +AnnotationAssertion(rdfs:label "apoptotic process involved in outflow tract morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (apoptotic process involved in heart valve morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:mtg_heart") "Any apoptotic process that contributes to the shaping of a heart valve.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-20T09:34:29Z") +AnnotationAssertion( "apoptosis involved in heart valve morphogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003276") +AnnotationAssertion(rdfs:label "apoptotic process involved in heart valve morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (apoptotic process involved in endocardial cushion morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:mtg_heart") "Any apoptotic process that contributes to the shaping of an endocardial cushion. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-20T09:37:03Z") +AnnotationAssertion( "apoptosis involved in endocardial cushion morphogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003277") +AnnotationAssertion(rdfs:label "apoptotic process involved in endocardial cushion morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (apoptotic process involved in heart morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:mtg_heart") "Any apoptotic process that contributes to the shaping of the heart.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-20T09:40:22Z") +AnnotationAssertion( "apoptosis involved in heart morphogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003278") +AnnotationAssertion(rdfs:label "apoptotic process involved in heart morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (cardiac septum development) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The progression of a cardiac septum over time, from its initial formation to the mature structure.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-20T09:45:13Z") +AnnotationAssertion(Annotation( "GOC:mtg_heart") "heart septum development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003279") +AnnotationAssertion(rdfs:label "cardiac septum development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (ventricular septum development) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The progression of the ventricular septum over time from its formation to the mature structure.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-20T10:04:51Z") +AnnotationAssertion(Annotation( "GOC:mtg_heart") "interventricular septum development") +AnnotationAssertion(Annotation( "GOC:mtg_heart") "septum inferius development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003281") +AnnotationAssertion(rdfs:label "ventricular septum development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (ventricular septum intermedium development) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The progression of the ventricular septum intermedium over time, from its formation to the mature structure.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-20T10:09:53Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003282") +AnnotationAssertion(rdfs:label "ventricular septum intermedium development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (atrial septum development) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The progression of the atrial septum over time, from its initial formation to the mature structure.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-20T10:10:38Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003283") +AnnotationAssertion(rdfs:label "atrial septum development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (septum primum development) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The progression of the septum primum over time, from its formation to the mature structure.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-20T10:12:26Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003284") +AnnotationAssertion(rdfs:label "septum primum development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (septum secundum development) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The progression of the septum secundum over time, from its initial formation to the mature structure.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-20T10:21:13Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003285") +AnnotationAssertion(rdfs:label "septum secundum development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (atrial septum intermedium development) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The progression of the atrial septum intermedium over time, from its formation to the mature structure.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-20T10:23:52Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003286") +AnnotationAssertion(rdfs:label "atrial septum intermedium development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (ventricular septum intermedium morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The developmental process in which a ventricular septum intermedium is generated and organized.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-20T10:58:48Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003288") +AnnotationAssertion(rdfs:label "ventricular septum intermedium morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (atrial septum primum morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which anatomical structure of an atrial septum primum is generated and organized.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-20T10:32:32Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003289") +AnnotationAssertion(rdfs:label "atrial septum primum morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (atrial septum secundum morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which anatomical structure of an atrial septum secundum is generated and organized.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-20T10:33:57Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003290") +AnnotationAssertion(rdfs:label "atrial septum secundum morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (atrial septum intermedium morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which anatomical structure of an atrial septum intermedium is generated and organized.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-20T10:35:04Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003291") +AnnotationAssertion(rdfs:label "atrial septum intermedium morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cardiac septum cell differentiation) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which an endocardial cushion cell becomes a cell of a cardiac septum.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-20T11:03:46Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003292") +AnnotationAssertion(rdfs:label "cardiac septum cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (heart valve cell differentiation) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which an endocardial cushion cell give rise to a cell that is part of a heart valve.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-20T11:06:46Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003293") +AnnotationAssertion(rdfs:label "heart valve cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (physiological muscle hypertrophy) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The enlargement or overgrowth of all or part of a muscle organ or tissue due to an increase in the size of its muscle cells. Physiological hypertrophy is a normal process during development.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-22T09:24:51Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003298") +AnnotationAssertion(rdfs:label "physiological muscle hypertrophy") +SubClassOf( ) + +# Class: (cardiac muscle hypertrophy) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The enlargement or overgrowth of all or part of the heart muscle due to an increase in size of cardiac muscle cells without cell division.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-22T10:33:56Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003300") +AnnotationAssertion(rdfs:label "cardiac muscle hypertrophy") +SubClassOf( ) + +# Class: (physiological cardiac muscle hypertrophy) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mtg_cardiac_conduct_nov11") Annotation( "GOC:mtg_heart") "The enlargement or overgrowth of all or part of the heart muscle due to an increase in size of cardiac muscle cells without cell division. This process contributes to the developmental growth of the heart.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-22T10:38:10Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003301") +AnnotationAssertion(rdfs:label "physiological cardiac muscle hypertrophy") +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (type B pancreatic cell differentiation) + +AnnotationAssertion(Annotation( "CL:0000169") Annotation( "GOC:dph") Annotation( "PMID:11076772") "The process in which relatively unspecialized cells acquire specialized structural and/or functional features of a type B pancreatic cell. A type B pancreatic cell is a cell located towards center of the islets of Langerhans that secretes insulin.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-26T09:27:23Z") +AnnotationAssertion(Annotation( "GOC:mah") "pancreatic B cell differentiation") +AnnotationAssertion(Annotation( "GOC:dph") "pancreatic beta cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003309") +AnnotationAssertion(rdfs:label "type B pancreatic cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (pancreatic A cell differentiation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:11076772") "The process in which relatively unspecialized cells acquire specialized structural and functional features of a pancreatic A cell. A pancreatic A cell is a cell in the pancreas that secretes glucagon.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-26T09:28:05Z") +AnnotationAssertion(Annotation( "GOC:dph") "pancreatic alpha cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003310") +AnnotationAssertion(rdfs:label "pancreatic A cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (pancreatic D cell differentiation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:11076772") "The process in which relatively unspecialized cells acquire specialized structural and functional features that characterize a pancreatic delta cell. A delta cell is a cell of the pancreas that produces somatostatin.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-26T09:30:27Z") +AnnotationAssertion(Annotation( "GOC:dph") "pancreatic delta cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003311") +AnnotationAssertion(rdfs:label "pancreatic D cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (pancreatic PP cell differentiation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:11076772") "The process in which relatively unspecialized cells acquire specialized structural and functional features of a pancreatic polypeptide-producing cell. A pancreatic polypeptide-producing cell is a cell in the pancreas that produces pancreatic polypeptide.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-26T09:32:32Z") +AnnotationAssertion(Annotation( "GOC:dph") "pancreatic polypeptide-producing cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003312") +AnnotationAssertion(rdfs:label "pancreatic PP cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (heart rudiment development) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The progression of the heart rudiment over time, from its initial formation to the mature structure. The heart rudiment is a cone-like structure that is formed when myocardial progenitor cells of the heart field fuse at the midline. The heart rudiment is the first structure of the heart tube.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-27T08:32:40Z") +AnnotationAssertion(Annotation( "GOC:mtg_heart") "heart cone development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003313") +AnnotationAssertion(rdfs:label "heart rudiment development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (heart rudiment morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which the anatomical structures of the heart rudiment are generated and organized.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-27T08:38:04Z") +AnnotationAssertion(Annotation( "GOC:mtg_heart") "heart cone morphogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003314") +AnnotationAssertion(rdfs:label "heart rudiment morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (heart rudiment formation) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The developmental process pertaining to the initial formation of the heart rudiment.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-27T08:43:37Z") +AnnotationAssertion(Annotation( "GOC:mtg_heart") "heart cone formation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003315") +AnnotationAssertion(rdfs:label "heart rudiment formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (pancreatic A cell development) + +AnnotationAssertion(Annotation( "GOC:dph") "The process whose specific outcome is the progression of a pancreatic A cell over time, from its formation to the mature structure. A pancreatic A cell is a cell in the pancreas that secretes glucagon.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-11-02T08:13:55Z") +AnnotationAssertion(Annotation( "GOC:dph") "pancreatic alpha cell development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003322") +AnnotationAssertion(rdfs:label "pancreatic A cell development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (type B pancreatic cell development) + +AnnotationAssertion(Annotation( "CL:0000169") Annotation( "GOC:dph") "The process whose specific outcome is the progression of a type B pancreatic cell over time, from its formation to the mature structure. A type B pancreatic cell is a cell located towards center of the islets of Langerhans that secretes insulin.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-11-02T08:20:11Z") +AnnotationAssertion(Annotation( "GOC:mah") "pancreatic B cell development") +AnnotationAssertion(Annotation( "GOC:dph") "pancreatic beta cell development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003323") +AnnotationAssertion(rdfs:label "type B pancreatic cell development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (pancreatic D cell development) + +AnnotationAssertion(Annotation( "GOC:dph") "The process whose specific outcome is the progression of a pancreatic delta cell over time, from its formation to the mature structure. A delta cell is a cell of the pancreas that produces somatostatin.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-11-02T08:23:26Z") +AnnotationAssertion(Annotation( "GOC:dph") "pancreatic delta cell development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003324") +AnnotationAssertion(rdfs:label "pancreatic D cell development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (pancreatic PP cell development) + +AnnotationAssertion(Annotation( "GOC:dph") "The process whose specific outcome is the progression of a pancreatic PP cell over time, from its formation to the mature structure. A pancreatic polypeptide-producing cell is a cell in the pancreas that produces pancreatic polypeptide.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-11-02T08:25:03Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003325") +AnnotationAssertion(rdfs:label "pancreatic PP cell development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (regulation of extracellular matrix constituent secretion) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the rate, frequency, or extent of the controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell or a group of cells.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-11-02T02:07:40Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003330") +AnnotationAssertion(rdfs:label "regulation of extracellular matrix constituent secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of extracellular matrix constituent secretion) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that increases the rate, frequency, or extent of the controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell or a group of cells.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-11-02T02:11:22Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003331") +AnnotationAssertion(rdfs:label "positive regulation of extracellular matrix constituent secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of extracellular matrix constituent secretion) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that decreases the rate, frequency, or extent the controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell or a group of cells.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-11-02T02:13:49Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003332") +AnnotationAssertion(rdfs:label "negative regulation of extracellular matrix constituent secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (amino acid transmembrane transport) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "The process in which an amino acid is transported across a membrane.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-11-02T02:36:11Z") +AnnotationAssertion( "amino acid membrane transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003333") +AnnotationAssertion(rdfs:comment "Note that this term is not intended for use in annotating lateral movement within membranes.") +AnnotationAssertion(rdfs:label "amino acid transmembrane transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (keratinocyte development) + +AnnotationAssertion(Annotation( "GOC:dph") "The process whose specific outcome is the progression of a keratinocyte over time, from its formation to the mature structure.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-11-24T08:55:57Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003334") +AnnotationAssertion(rdfs:label "keratinocyte development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (corneocyte development) + +AnnotationAssertion(Annotation( "GOC:dph") "The process whose specific outcome is the progression of the corneocyte over time, from its formation to the mature structure. A corneocyte is the last stage of development of a keratinocyte where the keratinocyte flattens, loses its nucleus and eventually delaminates from the epidermis.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-11-24T09:01:02Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003335") +AnnotationAssertion(rdfs:label "corneocyte development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (mesenchymal to epithelial transition involved in metanephros morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:yaf") "A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-11-24T09:29:49Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") "metanephric mesenchyme to epithelial transition") +AnnotationAssertion( "GO:0003337") +AnnotationAssertion(rdfs:label "mesenchymal to epithelial transition involved in metanephros morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (metanephros morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:yaf") "The process in which the anatomical structures of the metanephros are generated and organized.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-11-24T09:32:09Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003338") +AnnotationAssertion(rdfs:label "metanephros morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") "Any process that modulates the rate, frequency or extent of the transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-11-24T09:43:04Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003339") +AnnotationAssertion(rdfs:label "regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:yaf") "Any process that decreases the rate, frequency or extent of the transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-11-24T09:46:12Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003340") +AnnotationAssertion(rdfs:label "negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (cilium movement) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:jl") "The directed, self-propelled movement of a cilium.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/19809"^^xsd:anyURI) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-11-24T09:56:26Z") +AnnotationAssertion( "GO:0036142") +AnnotationAssertion( "microtubule-based flagellum movement") +AnnotationAssertion(Annotation( "GOC:bf") "flagellar movement") +AnnotationAssertion( "flagellum movement") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "ciliary motility") +AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "cilium beating") +AnnotationAssertion( "flagellar motility") +AnnotationAssertion( "GO:0003341") +AnnotationAssertion(rdfs:comment "Note that we deem cilium and microtubule-based flagellum to be equivalent.") +AnnotationAssertion(rdfs:label "cilium movement") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) +SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) +SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) +SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) +SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) +SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) +SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) +SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) +SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) +SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) +SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) +SubClassOf( ObjectAllValuesFrom( )) +DisjointClasses( ObjectSomeValuesFrom( )) +DisjointClasses( ObjectSomeValuesFrom( )) +DisjointClasses( ObjectSomeValuesFrom( )) +DisjointClasses( ObjectSomeValuesFrom( )) +DisjointClasses( ObjectSomeValuesFrom( )) +DisjointClasses( ObjectSomeValuesFrom( )) + +# Class: (proepicardium development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:18722343") "The progression of the proepicardium from its formation to the mature structure. The proepicardium is an outpouching of the septum transversum.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-12-01T10:30:17Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003342") +AnnotationAssertion(rdfs:label "proepicardium development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (septum transversum development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:18722343") "The progression of the septum transversum from its initial formation to the mature structure. The septum transversum is a portion of the trunk mesenchyme.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-12-01T10:40:17Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003343") +AnnotationAssertion(rdfs:label "septum transversum development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (pericardium morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:18722343") "The process in which the anatomical structure of the pericardium is generated and organized.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-12-01T10:46:34Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003344") +AnnotationAssertion(rdfs:label "pericardium morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cardiac endothelial cell differentiation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:18722343") "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cardiac endothelial cell.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-12-01T11:12:05Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003348") +AnnotationAssertion(rdfs:label "cardiac endothelial cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (pulmonary myocardium development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:17638577") "The progression of the pulmonary myocardium over time, from its initial formation to the mature structure. The pulmonary myocardium is the myocardial tissue present in the pulmonary vein.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-12-01T12:50:06Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003350") +AnnotationAssertion(rdfs:label "pulmonary myocardium development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (epithelial cilium movement involved in extracellular fluid movement) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:krc") "The directed, self-propelled movement of cilia of epithelial cells. Depending on the type of cell, there may be one or many cilia per cell. This movement is usually coordinated between many epithelial cells, and serves to move extracellular fluid.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/17181"^^xsd:anyURI) +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-12-03T10:08:25Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:cilia") "cilium movement involved in fluid flow") +AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "epithelial cilium beating") +AnnotationAssertion( "GO:0003351") +AnnotationAssertion(rdfs:label "epithelial cilium movement involved in extracellular fluid movement") +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of cilium movement) + +AnnotationAssertion(Annotation( "GOC:dph") "Any process that modulates the rate, frequency, or extent of cilium movement, the directed, self-propelled movement of a cilium.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-12-03T10:12:00Z") +AnnotationAssertion( "GO:1900172") +AnnotationAssertion( "regulation of microtubule-based flagellum movement") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of flagellar movement") +AnnotationAssertion( "regulation of flagellum movement") +AnnotationAssertion( "GO:0003352") +AnnotationAssertion(rdfs:comment "Note that we deem cilium and microtubule-based flagellum to be equivalent.") +AnnotationAssertion(rdfs:label "regulation of cilium movement") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of cilium movement) + +AnnotationAssertion(Annotation( "GOC:dph") "Any process that increases the rate, frequency, or extent of cilium movement, the directed, self-propelled movement of a cilium.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-12-03T10:16:10Z") +AnnotationAssertion( "GO:1900174") +AnnotationAssertion( "positive regulation of microtubule-based flagellum movement") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of flagellar movement") +AnnotationAssertion( "positive regulation of flagellum movement") +AnnotationAssertion( "GO:0003353") +AnnotationAssertion(rdfs:comment "Note that we deem cilium and microtubule-based flagellum to be equivalent.") +AnnotationAssertion(rdfs:label "positive regulation of cilium movement") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of cilium movement) + +AnnotationAssertion(Annotation( "GOC:dph") "Any process that decreases the rate, frequency, or extent of cilium movement, the directed, self-propelled movement of a cilium.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-12-03T10:17:47Z") +AnnotationAssertion( "GO:1900173") +AnnotationAssertion( "negative regulation of microtubule-based flagellum movement") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "negative regulation of flagellum movement") +AnnotationAssertion( "GO:0003354") +AnnotationAssertion(rdfs:comment "Note that we deem cilium and microtubule-based flagellum to be equivalent.") +AnnotationAssertion(rdfs:label "negative regulation of cilium movement") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (cilium movement involved in otolith formation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:krc") Annotation( "PMID:19043402") "The directed, self-propelled movement of cilia of inner ear epithelial cells, resulting the aggregation of otolith seed particles.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/17181"^^xsd:anyURI) +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-12-03T10:21:08Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003355") +AnnotationAssertion(rdfs:label "cilium movement involved in otolith formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (noradrenergic neuron differentiation) + +AnnotationAssertion(Annotation( "GOC:dph") "The process in which a relatively unspecialized cell acquires specialized features of an noradrenergic neuron, a neuron that secretes noradrenaline.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-12-03T10:34:30Z") +AnnotationAssertion(Annotation( "GOC:dph") "norepinephrine secreting neuron differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003357") +AnnotationAssertion(rdfs:label "noradrenergic neuron differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (noradrenergic neuron development) + +AnnotationAssertion(Annotation( "GOC:dph") "The process whose specific outcome is the progression of a noradrenergic neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-12-03T10:38:37Z") +AnnotationAssertion(Annotation( "GOC:dph") "norepinephrine secreting neuron development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003358") +AnnotationAssertion(rdfs:label "noradrenergic neuron development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (brainstem development) + +AnnotationAssertion(Annotation( "GOC:dph") "The progression of the brainstem from its formation to the mature structure. The brainstem is the part of the brain that connects the brain with the spinal cord.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-12-03T10:47:20Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003360") +AnnotationAssertion(rdfs:label "brainstem development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (noradrenergic neuron differentiation involved in brainstem development) + +AnnotationAssertion(Annotation( "GOC:dph") "The process in which a relatively unspecialized cell acquires specialized features of an noradrenergic neuron that is part of the brainstem.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-12-03T10:53:30Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003361") +AnnotationAssertion(rdfs:label "noradrenergic neuron differentiation involved in brainstem development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (establishment of cell polarity involved in ameboidal cell migration) + +AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "The specification and formation of anisotropic intracellular organization that contributes to the self-propelled directed movement of an ameboid cell.") +AnnotationAssertion( ) +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-12-08T04:50:41Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003365") +AnnotationAssertion(rdfs:label "establishment of cell polarity involved in ameboidal cell migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses( ObjectSomeValuesFrom( )) + +# Class: (establishment or maintenance of cytoskeleton polarity involved in ameboidal cell migration) + +AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures that contribute to the cell polarity of a migrating ameboid cell.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-12-08T05:42:46Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003371") +AnnotationAssertion(rdfs:label "establishment or maintenance of cytoskeleton polarity involved in ameboidal cell migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (establishment of cell polarity involved in gastrulation cell migration) + +AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "The specification and formation of anisotropic intracellular organization that contributes to the self-propelled directed movement of an ameboid cell taking part in gastrulation.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-12-09T06:54:44Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003379") +AnnotationAssertion(rdfs:label "establishment of cell polarity involved in gastrulation cell migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (establishment or maintenance of cytoskeleton polarity involved in gastrulation) + +AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures that contribute to the cell polarity of a migrating ameboid cell taking part in gastrulation.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-12-09T07:10:57Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003380") +AnnotationAssertion(rdfs:label "establishment or maintenance of cytoskeleton polarity involved in gastrulation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (epithelial cell morphogenesis involved in gastrulation) + +AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "The change in form that occurs when an epithelial cell progresses from it initial formation to its mature state, contributing to the process of gastrulation.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-12-09T07:18:53Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003381") +AnnotationAssertion(rdfs:label "epithelial cell morphogenesis involved in gastrulation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (epithelial cell morphogenesis) + +AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "The change in form that occurs when an epithelial cell progresses from its initial formation to its mature state.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-12-09T07:21:06Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003382") +AnnotationAssertion(rdfs:label "epithelial cell morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cell-cell signaling involved in amphid sensory organ development) + +AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that mediates the transfer of information from one cell to another and contributes to the progression of an amphid sensory organ over time, from its formation to the mature state.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-12-09T08:55:37Z") +AnnotationAssertion(Annotation( "GOC:mah") "cell-cell signalling involved in amphid sensory organ development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003385") +AnnotationAssertion(rdfs:label "cell-cell signaling involved in amphid sensory organ development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (amphid sensory organ development) + +AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "The progression of the amphid sensory organ over time, from its formation to the mature structure. Amphid sensory organs are the sensory organs of nematodes.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-12-09T09:09:20Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003386") +AnnotationAssertion(rdfs:label "amphid sensory organ development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (neuron differentiation involved in amphid sensory organ development) + +AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "The process in which a relatively unspecialized cell acquires specialized features of a neuron that contributes to the progression of the amphid sensory gland.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-12-09T09:15:00Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003387") +AnnotationAssertion(rdfs:label "neuron differentiation involved in amphid sensory organ development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (neuron development involved in amphid sensory organ development) + +AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "The process whose specific outcome is the progression of a neuron over time, that contributes to the development of the amphid sensory organ.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-12-09T09:18:06Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003388") +AnnotationAssertion(rdfs:label "neuron development involved in amphid sensory organ development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (glial cell differentiation involved in amphid sensory organ development) + +AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "The process in which a relatively unspecialized cell acquires the specialized features of a glial cell of the amphid sensory organ.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-12-09T09:55:27Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003398") +AnnotationAssertion(rdfs:label "glial cell differentiation involved in amphid sensory organ development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (optic vesicle formation) + +AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "The developmental process pertaining to the initial formation of the optic vesicle from the lateral wall of the forebrain. This process begins with the specific processes that contribute to the appearance of the vesicle and ends when the vesicle has evaginated. The optic vesicle is the evagination of neurectoderm that precedes formation of the optic cup.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-12-21T01:42:37Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003403") +AnnotationAssertion(rdfs:label "optic vesicle formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (optic vesicle morphogenesis) + +AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "The developmental process pertaining to the formation and shaping of the optic vesicle. This process begins with the specific processes that contribute to the appearance of the vesicle and ends when the vesicle has evaginated. The optic vesicle is the evagination of neurectoderm that precedes formation of the optic cup.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-12-21T01:54:34Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003404") +AnnotationAssertion(rdfs:label "optic vesicle morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (retinal pigment epithelium development) + +AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "The progression of the retinal pigment epithelium over time, from its initial formation to the mature structure. The retinal pigment epithelium is the melanin-containing layer of cells between the retina and the choroid that absorbs scattered and reflected light and removes waste products produced by the photoreceptor cells.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-12-21T02:04:27Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "RPE development") +AnnotationAssertion( "GO:0003406") +AnnotationAssertion(rdfs:label "retinal pigment epithelium development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (neural retina development) + +AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "The progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-12-21T02:15:14Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003407") +AnnotationAssertion(rdfs:label "neural retina development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cell motility involved in camera-type eye morphogenesis) + +AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another and contributes to the physical shaping or formation of the camera-type eye.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-12-21T03:04:27Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003411") +AnnotationAssertion(rdfs:label "cell motility involved in camera-type eye morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (chondrocyte differentiation involved in endochondral bone morphogenesis) + +AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "The process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte that will contribute to the development of a bone. A chondrocyte is a polymorphic cell that forms cartilage.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-12-22T08:39:58Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003413") +AnnotationAssertion(rdfs:label "chondrocyte differentiation involved in endochondral bone morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (chondrocyte morphogenesis involved in endochondral bone morphogenesis) + +AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "The process in which the structures of a chondrocyte that will contribute to bone development are generated and organized.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-12-22T08:42:55Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003414") +AnnotationAssertion(rdfs:label "chondrocyte morphogenesis involved in endochondral bone morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (chondrocyte hypertrophy) AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "The growth of a chondrocyte, where growth contributes to the progression of the chondrocyte over time.") @@ -28526,6 +52428,133 @@ AnnotationAssertion(rdfs:label "chon SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (endochondral bone growth) + +AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "The increase in size or mass of an endochondral bone that contributes to the shaping of the bone.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-12-22T08:52:55Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003416") +AnnotationAssertion(rdfs:label "endochondral bone growth") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (growth plate cartilage development) + +AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "The process whose specific outcome is the progression of the cartilage that will provide a scaffold for mineralization of endochondral bones as they elongate or grow.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-12-22T08:57:42Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003417") +AnnotationAssertion(rdfs:label "growth plate cartilage development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (growth plate cartilage chondrocyte differentiation) + +AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "The process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte that will contribute to the growth of a bone. A chondrocyte is a polymorphic cell that forms cartilage.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-12-22T09:00:56Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003418") +AnnotationAssertion(rdfs:label "growth plate cartilage chondrocyte differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (growth plate cartilage morphogenesis) + +AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "The process in which the anatomical structures of growth plate cartilage are generated and organized.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-12-22T09:21:30Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003422") +AnnotationAssertion(rdfs:label "growth plate cartilage morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (growth plate cartilage chondrocyte morphogenesis) + +AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "The process in which the structures of a chondrocyte in the growth plate cartilage are generated and organized.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-12-22T12:22:24Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003429") +AnnotationAssertion(rdfs:label "growth plate cartilage chondrocyte morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (growth plate cartilage chondrocyte growth) + +AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "The growth of a growth plate cartilage chondrocyte, where growth contributes to the progression of the chondrocyte over time from one condition to another.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-12-22T12:29:19Z") +AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "growth plate cartilage chondrocyte hypertrophy") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003430") +AnnotationAssertion(rdfs:label "growth plate cartilage chondrocyte growth") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (growth plate cartilage chondrocyte development) + +AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "The progression of a growth plate cartilage chondrocyte over time from after its fate commitment to the mature cell.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-12-22T12:32:49Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003431") +AnnotationAssertion(rdfs:label "growth plate cartilage chondrocyte development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cell growth involved in growth plate cartilage chondrocyte morphogenesis) + +AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "The growth of a growth plate cartilage chondrocyte, where growth contributes to the shaping of the chondrocyte over time.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-12-22T12:37:48Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003432") +AnnotationAssertion(rdfs:label "cell growth involved in growth plate cartilage chondrocyte morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (chondrocyte development involved in endochondral bone morphogenesis) + +AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "The progression of a chondrocyte over time from after its commitment to its mature state where the chondrocyte will contribute to the shaping of an endochondral bone.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-12-22T12:42:44Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003433") +AnnotationAssertion(rdfs:label "chondrocyte development involved in endochondral bone morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (regulation of cell adhesion involved in growth plate cartilage morphogenesis) + +AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the frequency, rate or extent of attachment of a cell to another cell or to the extracellular matrix and contributes to the shaping of the growth plate cartilage of an endochondral bone.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-12-22T01:28:15Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003436") +AnnotationAssertion(rdfs:label "regulation of cell adhesion involved in growth plate cartilage morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of cell communication involved in growth plate cartilage morphogenesis) + +AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the frequency, rate or extent of cell communication that contributes to the shaping of the growth plate cartilage.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-12-22T01:34:24Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0003437") +AnnotationAssertion(rdfs:label "regulation of cell communication involved in growth plate cartilage morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (molecular_function) AnnotationAssertion(Annotation( "GOC:pdt") "A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs.") @@ -28597,7 +52626,6 @@ AnnotationAssertion( ) AnnotationAssertion(rdfs:label "chromatin binding") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) # Class: (nuclear steroid receptor activity) @@ -28691,7 +52719,21 @@ AnnotationAssertion(Annotation(rdfs:label "INF-gamma induced phosphorylation of AnnotationAssertion(Annotation(rdfs:label "IRAK1 phosphorylates Pellino") "Reactome:R-HSA-937034") AnnotationAssertion(Annotation(rdfs:label "Unknown kinase phosphorylates NICD4") "Reactome:R-HSA-9604606") AnnotationAssertion(Annotation(rdfs:label "GTP-bound RAC1 contributes to MAPK8 activation") "Reactome:R-HSA-9673284") +AnnotationAssertion(Annotation(rdfs:label "JAK1-activated RAF1 phosphorylates MAPKs") "Reactome:R-HSA-9732753") AnnotationAssertion(Annotation(rdfs:label "IRAK1 phosphorylates Pellino upon TLR7/8 or 9 activation") "Reactome:R-HSA-975139") +AnnotationAssertion(Annotation(rdfs:label "PKR dimer autophosphorylates") "Reactome:R-HSA-9833820") +AnnotationAssertion(Annotation(rdfs:label "p-PKR dimer phosphorylates eIF2-alpha") "Reactome:R-HSA-9835885") +AnnotationAssertion(Annotation(rdfs:label "p-PKR dimer phosphorylates DHX9") "Reactome:R-HSA-9836159") +AnnotationAssertion(Annotation(rdfs:label "p-PKR dimer phosphorylates CDK1") "Reactome:R-HSA-9836184") +AnnotationAssertion(Annotation(rdfs:label "p-PKR dimer phosphorylates MKK6") "Reactome:R-HSA-9836322") +AnnotationAssertion(Annotation(rdfs:label "p-PKR dimer phosphorylates TP53 tetramer") "Reactome:R-HSA-9836362") +AnnotationAssertion(Annotation(rdfs:label "p-PKR dimer phosphorylates ILF3:ILF2") "Reactome:R-HSA-9836383") +AnnotationAssertion(Annotation(rdfs:label "p-PKR dimer phosphorylates MAPT") "Reactome:R-HSA-9836404") +AnnotationAssertion(Annotation(rdfs:label "p-PKR dimer phosphorylates SNCA") "Reactome:R-HSA-9836435") +AnnotationAssertion(Annotation(rdfs:label "p-PKR dimer phosphorylates HIV tat") "Reactome:R-HSA-9836449") +AnnotationAssertion(Annotation(rdfs:label "p-PKR dimer phosphorylates PTPN2") "Reactome:R-HSA-9836515") +AnnotationAssertion(Annotation(rdfs:label "p-PKR dimer phosphorylates SPHK1") "Reactome:R-HSA-9836617") +AnnotationAssertion(Annotation(rdfs:label "p-PKR dimer phosphorylates PPP2R5A") "Reactome:R-HSA-9836664") AnnotationAssertion( "protamine kinase activity") AnnotationAssertion( "molecular_function") AnnotationAssertion( "GO:0004672") @@ -28888,7 +52930,7 @@ AnnotationAssertion(Annotation(rdfs:label "Src kinases phosphorylate VAV") "Reactome:R-HSA-5218828") AnnotationAssertion(Annotation(rdfs:label "SRC-1 phosphorylates PTK2-beta") "Reactome:R-HSA-5218830") AnnotationAssertion(Annotation(rdfs:label "p-Y402-PTK2B phosphorylates p-5Y,S732-PTK2 on Y407") "Reactome:R-HSA-5218851") -AnnotationAssertion(Annotation(rdfs:label "AXL autophosphorylates on Y772 and Y814") "Reactome:R-HSA-5357429") +AnnotationAssertion(Annotation(rdfs:label "AXL autophosphorylates on Y779 and Y821") "Reactome:R-HSA-5357429") AnnotationAssertion(Annotation(rdfs:label "1,3-beta-D-glucan:p-Y15-CLEC7A:SYK phosphorylates PLCG") "Reactome:R-HSA-5607745") AnnotationAssertion(Annotation(rdfs:label "SRC kinase phosphorylates CLEC7A:1,3-beta-D-glucan") "Reactome:R-HSA-5607750") AnnotationAssertion(Annotation(rdfs:label "LYN and FYN phosphorylate FCER1G in CLEC6A:FCERG and CLEC4E:FCERG") "Reactome:R-HSA-5621355") @@ -28983,8 +53025,8 @@ AnnotationAssertion(Annotation(rdfs:label "SRC,YES1 phosphorylate YAP1") "Reactome:R-HSA-8942607") AnnotationAssertion(Annotation(rdfs:label "p-S13, FUNDC1 is phosphorylated by CK2 at Tyr18") "Reactome:R-HSA-8948143") AnnotationAssertion(Annotation(rdfs:label "ABL1 phosphorylates YAP1") "Reactome:R-HSA-8956659") -AnnotationAssertion(Annotation(rdfs:label "G protein alpha (i)-SRC complex catalyzes SRC to p-Y416-SRC") "Reactome:R-HSA-8964242") -AnnotationAssertion(Annotation(rdfs:label "G alpha (s):GTP:SRC catalyzes SRC to p-Y416-SRC") "Reactome:R-HSA-8964252") +AnnotationAssertion(Annotation(rdfs:label "G protein alpha (i)-SRC complex catalyzes SRC to p-Y419-SRC") "Reactome:R-HSA-8964242") +AnnotationAssertion(Annotation(rdfs:label "G alpha (s):GTP:SRC catalyzes SRC to p-Y419-SRC") "Reactome:R-HSA-8964252") AnnotationAssertion(Annotation(rdfs:label "JAK2 bound to IL12RB2:IL12RB2 phosphorylate STAT4") "Reactome:R-HSA-8983872") AnnotationAssertion(Annotation(rdfs:label "Phospho-JAK2 phosphorylates EPOR") "Reactome:R-HSA-9006323") AnnotationAssertion(Annotation(rdfs:label "JAK2 transphosphorylates and is activated in response to Erythropoietin") "Reactome:R-HSA-9006332") @@ -29076,9 +53118,10 @@ AnnotationAssertion(Annotation(rdfs:label "ALK mutants phosphorylate STAT3") "Reactome:R-HSA-9712086") AnnotationAssertion(Annotation(rdfs:label "ALK fusions phosphorylate FRS") "Reactome:R-HSA-9712087") AnnotationAssertion(Annotation(rdfs:label "SRC phosphorylates RHOU") "Reactome:R-HSA-9726848") +AnnotationAssertion(Annotation(rdfs:label "JAK1-mediated phosphorylation of RAF1") "Reactome:R-HSA-9732738") AnnotationAssertion(Annotation(rdfs:label "CSF1R trans-autophosphorylates on tyrosine-561") "Reactome:R-HSA-9733314") AnnotationAssertion(Annotation(rdfs:label "Src family kinases phosphorylate CBL in CSF1 dimer:p-Y561-CSF1R dimer:CBL") "Reactome:R-HSA-9733323") -AnnotationAssertion(Annotation(rdfs:label "BACH1 is phosphorylated at tyrosine 486") "Reactome:R-HSA-9762209") +AnnotationAssertion(Annotation(rdfs:label "BACH1 is phosphorylated at tyrosine 483") "Reactome:R-HSA-9762209") AnnotationAssertion(Annotation(rdfs:label "JAK2 phosphorylation of GHR") "Reactome:R-HSA-982807") AnnotationAssertion(Annotation(rdfs:label "p-6Y-SYK phosphorylates BLNK (SLP65)") "Reactome:R-HSA-983703") AnnotationAssertion(Annotation(rdfs:label "SYK autophosphorylates at the activated BCR") "Reactome:R-HSA-983707") @@ -29414,8 +53457,6 @@ SubClassOf( "GOC:ai") Annotation( "GOC:dgf") "Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells.") AnnotationAssertion( "GO:0005478") -AnnotationAssertion(Annotation(rdfs:label "Virion-associated M2 protein mediated ion infusion") "Reactome:R-HSA-168313") -AnnotationAssertion(Annotation(rdfs:label "SMAD7:SMURF1 complex is exported to the cytosol") "Reactome:R-HSA-178215") AnnotationAssertion( "molecular_function") AnnotationAssertion( "carrier") AnnotationAssertion( "GO:0005215") @@ -29861,9 +53902,11 @@ AnnotationAssertion(Annotation( "cellular_component") AnnotationAssertion( "GO:0005583") AnnotationAssertion(rdfs:label "fibrillar collagen trimer") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) +DisjointClasses( ) # Class: (collagen type I trimer) @@ -29980,7 +54023,81 @@ SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectAllValuesFrom( )) DisjointClasses( ) +DisjointClasses( ) DisjointClasses( ObjectSomeValuesFrom( )) +DisjointClasses( ObjectSomeValuesFrom( )) + +# Class: (nuclear envelope) + +AnnotationAssertion(Annotation( "ISBN:0198547684") "The double lipid bilayer enclosing the nucleus and separating its contents from the rest of the cytoplasm; includes the intermembrane space, a gap of width 20-40 nm (also called the perinuclear space).") +AnnotationAssertion( "GO:0005636") +AnnotationAssertion( "Wikipedia:Nuclear_envelope") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0005635") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "nuclear envelope") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (nuclear outer membrane) + +AnnotationAssertion(Annotation( "ISBN:0198547684") "The outer, i.e. cytoplasm-facing, lipid bilayer of the nuclear envelope; continuous with the endoplasmic reticulum of the cell and sometimes studded with ribosomes.") +AnnotationAssertion( "NIF_Subcellular:sao1617136075") +AnnotationAssertion( "nucleus outer envelope") +AnnotationAssertion( "perinuclear membrane") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0005640") +AnnotationAssertion(rdfs:label "nuclear outer membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (chromosome) + +AnnotationAssertion(Annotation( "ISBN:0198547684") "A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information.") +AnnotationAssertion( "Wikipedia:Chromosome") +AnnotationAssertion( "interphase chromosome") +AnnotationAssertion( "prophase chromosome") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "chromatid") +AnnotationAssertion( "GO:0005694") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:comment "Chromosomes include parts that are not part of the chromatin. Examples include the kinetochore.") +AnnotationAssertion(rdfs:label "chromosome") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (nucleolus) + +AnnotationAssertion(Annotation( "ISBN:0198506732") "A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.") +AnnotationAssertion( "NIF_Subcellular:sao1820400233") +AnnotationAssertion( "Wikipedia:Nucleolus") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0005730") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "nucleolus") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) # Class: (cytoplasm) @@ -30000,6 +54117,47 @@ AnnotationAssertion(rdfs:label "cyto SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (lysosome) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "ISBN:0198506732") "A small lytic vacuole that has cell cycle-independent morphology found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions.") +AnnotationAssertion( ) +AnnotationAssertion( "NIF_Subcellular:sao585356902") +AnnotationAssertion( "Wikipedia:Lysosome") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0005764") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "lysosome") +SubClassOf( ) +SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses( ObjectSomeValuesFrom( )) + +# Class: (lysosomal membrane) + +AnnotationAssertion(Annotation( "GOC:ai") "The lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm.") +AnnotationAssertion( ) +AnnotationAssertion( "lysosome membrane") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0005765") +AnnotationAssertion(rdfs:label "lysosomal membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses( ObjectSomeValuesFrom( )) + +# Class: (primary lysosome) + +AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0815316194") "A lysosome before it has fused with a vesicle or vacuole.") +AnnotationAssertion( "NIF_Subcellular:sao1140587416") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0005766") +AnnotationAssertion(rdfs:label "primary lysosome") +SubClassOf( ) + # Class: (vacuole) AnnotationAssertion(Annotation( "GOC:mtg_sensu") Annotation( "ISBN:0198506732") "A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol.") @@ -30021,6 +54179,109 @@ AnnotationAssertion(rdfs:label "vacu SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (vacuolar membrane) + +AnnotationAssertion(Annotation( "GOC:ai") "The lipid bilayer surrounding the vacuole and separating its contents from the cytoplasm of the cell.") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0005774") +AnnotationAssertion(rdfs:label "vacuolar membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (vacuolar lumen) + +AnnotationAssertion(Annotation( "ISBN:0198506732") "The volume enclosed within the vacuolar membrane.") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0005775") +AnnotationAssertion(rdfs:label "vacuolar lumen") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (Golgi apparatus) + +AnnotationAssertion(Annotation( "ISBN:0198506732") "A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways.") +AnnotationAssertion( "Golgi") +AnnotationAssertion( "NIF_Subcellular:sao451912436") +AnnotationAssertion( "Wikipedia:Golgi_apparatus") +AnnotationAssertion( "Golgi complex") +AnnotationAssertion( "Golgi ribbon") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0005794") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:comment "Note that the Golgi apparatus can be located in various places in the cytoplasm. In plants and lower animal cells, the Golgi apparatus exists as many copies of discrete stacks dispersed throughout the cytoplasm, while the Golgi apparatus of interphase mammalian cells is a juxtanuclear, often pericentriolar reticulum, where the discrete Golgi stacks are stitched together to form a compact and interconnected ribbon, sometimes called the Golgi ribbon.") +AnnotationAssertion(rdfs:label "Golgi apparatus") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectAllValuesFrom( )) + +# Class: (Golgi-associated vesicle) + +AnnotationAssertion(Annotation( "GOC:mah") "Any vesicle associated with the Golgi complex and involved in mediating transport within the Golgi or between the Golgi and other parts of the cell.") +AnnotationAssertion( "NIF_Subcellular:sao819927218") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "Golgi vesicle") +AnnotationAssertion(Annotation( "NIF_Subcellular:sao138219748") "vesicular component") +AnnotationAssertion( "GO:0005798") +AnnotationAssertion(rdfs:comment "Note that this definition includes vesicles that are transiently associated with the Golgi.") +AnnotationAssertion(rdfs:label "Golgi-associated vesicle") +SubClassOf( ) + +# Class: (cytosol) + +AnnotationAssertion(Annotation( "GOC:hjd") Annotation( "GOC:jl") "The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.") +AnnotationAssertion( "NIF_Subcellular:sao101633890") +AnnotationAssertion( "Wikipedia:Cytosol") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0005829") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "cytosol") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +DisjointClasses( ObjectSomeValuesFrom( )) +DisjointClasses( ObjectSomeValuesFrom( )) + +# Class: (ribosome) + +AnnotationAssertion(Annotation( "ISBN:0198506732") "An intracellular organelle, about 200 A in diameter, consisting of RNA and protein. It is the site of protein biosynthesis resulting from translation of messenger RNA (mRNA). It consists of two subunits, one large and one small, each containing only protein and RNA. Both the ribosome and its subunits are characterized by their sedimentation coefficients, expressed in Svedberg units (symbol: S). Hence, the prokaryotic ribosome (70S) comprises a large (50S) subunit and a small (30S) subunit, while the eukaryotic ribosome (80S) comprises a large (60S) subunit and a small (40S) subunit. Two sites on the ribosomal large subunit are involved in translation, namely the aminoacyl site (A site) and peptidyl site (P site). Ribosomes from prokaryotes, eukaryotes, mitochondria, and chloroplasts have characteristically distinct ribosomal proteins.") +AnnotationAssertion( "GO:0033279") +AnnotationAssertion( "NIF_Subcellular:sao1429207766") +AnnotationAssertion( "Wikipedia:Ribosome") +AnnotationAssertion(Annotation( "NIF_Subcellular:sao1139385046") "free ribosome") +AnnotationAssertion(Annotation( "NIF_Subcellular:sao1291545653") "membrane bound ribosome") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "ribosomal RNA") +AnnotationAssertion( "GO:0005840") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "ribosome") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (cytoskeleton) AnnotationAssertion(Annotation( "GOC:mah") Annotation( "PMID:16959967") Annotation( "PMID:27419875") "A cellular structure that forms the internal framework of eukaryotic and prokaryotic cells. The cytoskeleton includes intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles.") @@ -30041,6 +54302,53 @@ AnnotationAssertion( "cytoskeleton") SubClassOf( ) +# Class: (microtubule) + +AnnotationAssertion(Annotation( "ISBN:0879693568") "Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle.") +AnnotationAssertion( "NIF_Subcellular:sao1846835077") +AnnotationAssertion( "Wikipedia:Microtubule") +AnnotationAssertion( "microtubuli") +AnnotationAssertion( "microtubulus") +AnnotationAssertion(Annotation( "NIF_Subcellular:sao248349196") "neurotubule") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0005874") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "microtubule") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (axonemal microtubule) + +AnnotationAssertion(Annotation( "GOC:cilia") Annotation( "ISBN:0815316194") "A microtubule in the axoneme of a eukaryotic cilium or flagellum; an axoneme contains nine modified doublet microtubules, which may or may not surround a pair of single microtubules.") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0005879") +AnnotationAssertion(rdfs:label "axonemal microtubule") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (nuclear microtubule) + +AnnotationAssertion(Annotation( "GOC:mah") "Any microtubule in the nucleus of a cell.") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0005880") +AnnotationAssertion(rdfs:label "nuclear microtubule") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cytoplasmic microtubule) + +AnnotationAssertion(Annotation( "GOC:mah") "Any microtubule in the cytoplasm of a cell.") +AnnotationAssertion( "non-spindle-associated astral microtubule") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0005881") +AnnotationAssertion(rdfs:label "cytoplasmic microtubule") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (intermediate filament) AnnotationAssertion(Annotation( "ISBN:0198506732") Annotation( "http://www.cytochemistry.net/Cell-biology/intermediate_filaments.htm") "A cytoskeletal structure that forms a distinct elongated structure, characteristically 10 nm in diameter, that occurs in the cytoplasm of eukaryotic cells. Intermediate filaments form a fibrous system, composed of chemically heterogeneous subunits and involved in mechanically integrating the various components of the cytoplasmic space. Intermediate filaments may be divided into five chemically distinct classes: Type I, acidic keratins; Type II, basic keratins; Type III, including desmin, vimentin and others; Type IV, neurofilaments and related filaments; and Type V, lamins.") @@ -30104,6 +54412,18 @@ AnnotationAssertion(rdfs:label "plas SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (insulin receptor complex) + +AnnotationAssertion(Annotation( "ISBN:0198506732") "A disulfide-bonded, heterotetrameric receptor complex. The alpha chains are entirely extracellular, while each beta chain has one transmembrane domain. The ligand binds to the alpha subunit extracellular domain and the kinase is associated with the beta subunit intracellular domain.") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0005899") +AnnotationAssertion(rdfs:label "insulin receptor complex") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectAllValuesFrom( )) + # Class: (microvillus) AnnotationAssertion(Annotation( "ISBN:0815316194") "Thin cylindrical membrane-covered projections on the surface of an animal cell containing a core bundle of actin filaments. Present in especially large numbers on the absorptive surface of intestinal cells.") @@ -30197,6 +54517,40 @@ DisjointClasses( ObjectSomeValuesFrom DisjointClasses( ObjectSomeValuesFrom( )) DisjointClasses( ObjectSomeValuesFrom( )) +# Class: (axoneme) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:cilia") Annotation( "ISBN:0198547684") "The bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements.") +AnnotationAssertion( "GO:0035085") +AnnotationAssertion( "GO:0035086") +AnnotationAssertion( "Wikipedia:Axoneme") +AnnotationAssertion( "ciliary axoneme") +AnnotationAssertion( "cilium axoneme") +AnnotationAssertion( "flagellar axoneme") +AnnotationAssertion( "flagellum axoneme") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0005930") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:comment "Note that cilia and eukaryotic flagella are deemed to be equivalent. In diplomonad species, such as Giardia, the axoneme may extend intracellularly up to 5um away from the plane of the plasma membrane.") +AnnotationAssertion(rdfs:label "axoneme") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cell cortex) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "ISBN:0815316194") "The region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins.") +AnnotationAssertion( "Wikipedia:Cell_cortex") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "cell periphery") +AnnotationAssertion( "peripheral cytoplasm") +AnnotationAssertion( "GO:0005938") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "cell cortex") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (carbohydrate metabolic process) AnnotationAssertion(Annotation( "GOC:mah") Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.") @@ -30221,8 +54575,23 @@ AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "carbohydrate metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (polysaccharide metabolic process) + +AnnotationAssertion(Annotation( "ISBN:0198547684") "The chemical reactions and pathways involving a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically.") +AnnotationAssertion( "GO:0044263") +AnnotationAssertion( "polysaccharide metabolism") +AnnotationAssertion( "glycan metabolic process") +AnnotationAssertion( "glycan metabolism") +AnnotationAssertion( "multicellular organismal polysaccharide metabolic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0005976") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "polysaccharide metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (glycogen metabolic process) AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues in alpha-(1->4) glycosidic linkage, joined together by alpha-(1->6) glycosidic linkages.") @@ -30230,6 +54599,7 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0005977") AnnotationAssertion(rdfs:label "glycogen metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ) @@ -30245,9 +54615,24 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0005978") AnnotationAssertion(rdfs:label "glycogen biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) +# Class: (regulation of glycogen biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen.") +AnnotationAssertion( "regulation of glycogen anabolism") +AnnotationAssertion( "regulation of glycogen biosynthesis") +AnnotationAssertion( "regulation of glycogen formation") +AnnotationAssertion( "regulation of glycogen synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0005979") +AnnotationAssertion(rdfs:label "regulation of glycogen biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + # Class: (glycogen catabolic process) AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues.") @@ -30259,6 +54644,83 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:0005980") AnnotationAssertion(rdfs:label "glycogen catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of glycogen catabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glycogen.") +AnnotationAssertion( "regulation of glycogen breakdown") +AnnotationAssertion( "regulation of glycogen catabolism") +AnnotationAssertion( "regulation of glycogen degradation") +AnnotationAssertion(Annotation( "GOC:sl") "regulation of glycogenolysis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0005981") +AnnotationAssertion(rdfs:label "regulation of glycogen catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (monosaccharide metabolic process) + +AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving monosaccharides, the simplest carbohydrates. They are polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides.") +AnnotationAssertion( "monosaccharide metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0005996") +AnnotationAssertion(rdfs:label "monosaccharide metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (glucose metabolic process) + +AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving glucose, the aldohexose gluco-hexose. D-glucose is dextrorotatory and is sometimes known as dextrose; it is an important source of energy for living organisms and is found free as well as combined in homo- and hetero-oligosaccharides and polysaccharides.") +AnnotationAssertion(Annotation( "GOC:vw") "cellular glucose metabolic process") +AnnotationAssertion( "glucose metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006006") +AnnotationAssertion(rdfs:label "glucose metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (glucose catabolic process) + +AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways resulting in the breakdown of glucose, the aldohexose gluco-hexose.") +AnnotationAssertion( "glucose breakdown") +AnnotationAssertion( "glucose catabolism") +AnnotationAssertion( "glucose degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006007") +AnnotationAssertion(rdfs:label "glucose catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (D-ribose metabolic process) + +AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving D-ribose (ribo-pentose). As beta-D-ribofuranose, D-ribose forms the glycose group of all ribonucleosides, ribonucleotides and ribonucleic acids, and also of ribose phosphates, various glycosides, some coenzymes and some forms of vitamin B12.") +AnnotationAssertion( "D-ribose metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006014") +AnnotationAssertion(rdfs:label "D-ribose metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (aminoglycan metabolic process) + +AnnotationAssertion(Annotation( "GOC:ai") Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages.") +AnnotationAssertion( "aminoglycan metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006022") +AnnotationAssertion(rdfs:label "aminoglycan metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (aminoglycan biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:ai") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages.") +AnnotationAssertion( "aminoglycan anabolism") +AnnotationAssertion( "aminoglycan biosynthesis") +AnnotationAssertion( "aminoglycan formation") +AnnotationAssertion( "aminoglycan synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006023") +AnnotationAssertion(rdfs:label "aminoglycan biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (glycosaminoglycan biosynthetic process) @@ -30270,6 +54732,100 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0006024") AnnotationAssertion(rdfs:label "glycosaminoglycan biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (aminoglycan catabolic process) + +AnnotationAssertion(Annotation( "GOC:ai") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages.") +AnnotationAssertion( "aminoglycan breakdown") +AnnotationAssertion( "aminoglycan catabolism") +AnnotationAssertion( "aminoglycan degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006026") +AnnotationAssertion(rdfs:label "aminoglycan catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (glycosaminoglycan catabolic process) + +AnnotationAssertion(Annotation( "ISBN:0192800981") "The chemical reactions and pathways resulting in the breakdown of glycosaminoglycans, any one of a group of polysaccharides that contain amino sugars.") +AnnotationAssertion( "glycosaminoglycan breakdown") +AnnotationAssertion( "glycosaminoglycan catabolism") +AnnotationAssertion( "glycosaminoglycan degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006027") +AnnotationAssertion(rdfs:label "glycosaminoglycan catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (proteoglycan metabolic process) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans.") +AnnotationAssertion( "proteoglycan metabolism") +AnnotationAssertion( "proteoglycan sulfate transfer") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006029") +AnnotationAssertion(rdfs:label "proteoglycan metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (chitin metabolic process) + +AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues.") +AnnotationAssertion( "beta-1,4-linked N-acetylglucosamine metabolic process") +AnnotationAssertion( "beta-1,4-linked N-acetylglucosamine metabolism") +AnnotationAssertion( "chitin metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006030") +AnnotationAssertion(rdfs:label "chitin metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (chitin biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues.") +AnnotationAssertion( "beta-1,4-linked N-acetylglucosamine biosynthesis") +AnnotationAssertion( "beta-1,4-linked N-acetylglucosamine biosynthetic process") +AnnotationAssertion( "chitin anabolism") +AnnotationAssertion( "chitin biosynthesis") +AnnotationAssertion( "chitin formation") +AnnotationAssertion( "chitin synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006031") +AnnotationAssertion(rdfs:label "chitin biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (chitin catabolic process) + +AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues.") +AnnotationAssertion( "beta-1,4-linked N-acetylglucosamine catabolic process") +AnnotationAssertion( "beta-1,4-linked N-acetylglucosamine catabolism") +AnnotationAssertion( "chitin breakdown") +AnnotationAssertion( "chitin catabolism") +AnnotationAssertion( "chitin degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006032") +AnnotationAssertion(rdfs:label "chitin catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (amino sugar metabolic process) + +AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0192801023") "The chemical reactions and pathways involving any amino sugar, sugars containing an amino group in place of a hydroxyl group.") +AnnotationAssertion( "amino sugar metabolism") +AnnotationAssertion( "aminosaccharide metabolic process") +AnnotationAssertion( "aminosaccharide metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006040") +AnnotationAssertion(rdfs:label "amino sugar metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (alcohol metabolic process) + +AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom.") +AnnotationAssertion( "alcohol metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006066") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "alcohol metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) # Class: (cellular aldehyde metabolic process) @@ -30281,6 +54837,7 @@ AnnotationAssertion( "GO:0006081") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "cellular aldehyde metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ) @@ -30294,11 +54851,21 @@ AnnotationAssertion( "GO:0006082") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "organic acid metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) +# Class: (acetate metabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways involving acetate, the anion of acetic acid.") +AnnotationAssertion( "acetate metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006083") +AnnotationAssertion(rdfs:label "acetate metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (generation of precursor metabolites and energy) AnnotationAssertion(Annotation( "GOC:jl") "The chemical reactions and pathways resulting in the formation of precursor metabolites, substances from which energy is derived, and any process involved in the liberation of energy from these substances.") @@ -30320,6 +54887,42 @@ AnnotationAssertion( "generation of precursor metabolites and energy") SubClassOf( ) +# Class: (gluconeogenesis) + +AnnotationAssertion(Annotation( "MetaCyc:GLUCONEO-PWY") "The formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol.") +AnnotationAssertion( "MetaCyc:GLUCONEO-PWY") +AnnotationAssertion( "Wikipedia:Gluconeogenesis") +AnnotationAssertion( "glucose biosynthesis") +AnnotationAssertion( "glucose biosynthetic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006094") +AnnotationAssertion(rdfs:label "gluconeogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of carbohydrate metabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving carbohydrates.") +AnnotationAssertion( "regulation of carbohydrate metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006109") +AnnotationAssertion(rdfs:label "regulation of carbohydrate metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of gluconeogenesis) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of gluconeogenesis, the formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2013-01-18T12:47:43Z") +AnnotationAssertion( "GO:0090526") +AnnotationAssertion( "regulation of glucose biosynthesis") +AnnotationAssertion( "regulation of glucose biosynthetic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "regulation of gluconeogenesis involved in cellular glucose homeostasis") +AnnotationAssertion( "GO:0006111") +AnnotationAssertion(rdfs:label "regulation of gluconeogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (energy reserve metabolic process) AnnotationAssertion(Annotation( "GOC:mah") "The chemical reactions and pathways by which a cell derives energy from stored compounds such as fats or glycogen.") @@ -30330,6 +54933,300 @@ AnnotationAssertion( "energy reserve metabolic process") SubClassOf( ) +# Class: (fermentation) + +AnnotationAssertion(Annotation( "GOC:curators") Annotation( "ISBN:0201090910") Annotation( "MetaCyc:Fermentation") "The anaerobic enzymatic conversion of organic compounds, especially carbohydrates, coupling the oxidation and reduction of NAD/H and the generation of adenosine triphosphate (ATP).") +AnnotationAssertion( "MetaCyc:FERMENTATION-PWY") +AnnotationAssertion( "Wikipedia:Fermentation_(biochemistry)") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006113") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "fermentation") +SubClassOf( ) + +# Class: (nucleobase-containing compound metabolic process) + +AnnotationAssertion(Annotation( "GOC:ai") "Any cellular metabolic process involving nucleobases, nucleosides, nucleotides and nucleic acids.") +AnnotationAssertion( "GO:0055134") +AnnotationAssertion( "cellular nucleobase, nucleoside, nucleotide and nucleic acid metabolic process") +AnnotationAssertion( "cellular nucleobase, nucleoside, nucleotide and nucleic acid metabolism") +AnnotationAssertion( "nucleobase, nucleoside, nucleotide and nucleic acid metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "nucleobase, nucleoside and nucleotide metabolic process") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "nucleobase, nucleoside, nucleotide and nucleic acid metabolic process") +AnnotationAssertion( "GO:0006139") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "nucleobase-containing compound metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of nucleotide metabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleotides.") +AnnotationAssertion( "regulation of nucleotide metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006140") +AnnotationAssertion(rdfs:label "regulation of nucleotide metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of purine nucleobase metabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving purines.") +AnnotationAssertion(Annotation( "GOC:go_curators") "regulation of purine base metabolic process") +AnnotationAssertion( "regulation of purine base metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006141") +AnnotationAssertion(rdfs:label "regulation of purine nucleobase metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (purine nucleobase metabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways involving purine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, which include adenine and guanine.") +AnnotationAssertion(Annotation( "GOC:go_curators") "purine base metabolic process") +AnnotationAssertion( "purine base metabolism") +AnnotationAssertion( "purine metabolic process") +AnnotationAssertion( "purine metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006144") +AnnotationAssertion(rdfs:label "purine nucleobase metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (purine nucleobase catabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways resulting in the breakdown of purine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, which include adenine and guanine.") +AnnotationAssertion( "purine base breakdown") +AnnotationAssertion(Annotation( "GOC:go_curators") "purine base catabolic process") +AnnotationAssertion( "purine base catabolism") +AnnotationAssertion( "purine base degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006145") +AnnotationAssertion(rdfs:label "purine nucleobase catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (adenine catabolic process) + +AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of adenine, 6-aminopurine, one of the 5 main bases found in nucleic acids and a component of numerous important derivatives of its corresponding ribonucleoside, adenosine.") +AnnotationAssertion( "adenine breakdown") +AnnotationAssertion( "adenine catabolism") +AnnotationAssertion( "adenine degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006146") +AnnotationAssertion(rdfs:label "adenine catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (purine nucleoside catabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways resulting in the breakdown of purine nucleoside, one of a family of organic molecules consisting of a purine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside).") +AnnotationAssertion( "purine nucleoside breakdown") +AnnotationAssertion( "purine nucleoside catabolism") +AnnotationAssertion( "purine nucleoside degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006152") +AnnotationAssertion(rdfs:label "purine nucleoside catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (adenosine catabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways resulting in the breakdown of adenosine, adenine riboside, a ribonucleoside found widely distributed in cells of every type as the free nucleoside and in combination in nucleic acids and various nucleoside coenzymes.") +AnnotationAssertion( "GO:0006156") +AnnotationAssertion( "adenosine breakdown") +AnnotationAssertion( "adenosine catabolism") +AnnotationAssertion( "adenosine degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "adenosine phosphorolysis") +AnnotationAssertion( "GO:0006154") +AnnotationAssertion(rdfs:label "adenosine catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (purine nucleotide metabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving a purine nucleotide, a compound consisting of nucleoside (a purine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.") +AnnotationAssertion( "purine nucleotide metabolism") +AnnotationAssertion( "purine metabolic process") +AnnotationAssertion( "purine metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006163") +AnnotationAssertion(rdfs:label "purine nucleotide metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (purine nucleotide biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of a purine nucleotide, a compound consisting of nucleoside (a purine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.") +AnnotationAssertion( "MetaCyc:DENOVOPURINE2-PWY") +AnnotationAssertion( "purine nucleotide anabolism") +AnnotationAssertion( "purine nucleotide biosynthesis") +AnnotationAssertion( "purine nucleotide formation") +AnnotationAssertion( "purine nucleotide synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006164") +AnnotationAssertion(rdfs:label "purine nucleotide biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (ADP biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways resulting in the formation of ADP, adenosine 5'-diphosphate.") +AnnotationAssertion( "ADP anabolism") +AnnotationAssertion( "ADP biosynthesis") +AnnotationAssertion( "ADP formation") +AnnotationAssertion( "ADP synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006172") +AnnotationAssertion(rdfs:label "ADP biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (purine nucleotide catabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of a purine nucleotide, a compound consisting of nucleoside (a purine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.") +AnnotationAssertion( "purine nucleotide breakdown") +AnnotationAssertion( "purine nucleotide catabolism") +AnnotationAssertion( "purine nucleotide degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006195") +AnnotationAssertion(rdfs:label "purine nucleotide catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (DNA metabolic process) + +AnnotationAssertion(Annotation( "ISBN:0198506732") "Any cellular metabolic process involving deoxyribonucleic acid. This is one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides.") +AnnotationAssertion( "GO:0055132") +AnnotationAssertion( "DNA metabolism") +AnnotationAssertion( "cellular DNA metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006259") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "DNA metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (DNA catabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198506732") "The cellular DNA metabolic process resulting in the breakdown of DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long unbranched macromolecule formed from one or two strands of linked deoxyribonucleotides, the 3'-phosphate group of each constituent deoxyribonucleotide being joined in 3',5'-phosphodiester linkage to the 5'-hydroxyl group of the deoxyribose moiety of the next one.") +AnnotationAssertion( "DNA breakdown") +AnnotationAssertion( "DNA catabolism") +AnnotationAssertion( "DNA degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006308") +AnnotationAssertion(rdfs:label "DNA catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (apoptotic DNA fragmentation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mah") Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:tb") Annotation( "ISBN:0721639976") Annotation( "PMID:15723341") Annotation( "PMID:23379520") "The cleavage of DNA during apoptosis, which usually occurs in two stages: cleavage into fragments of about 50 kbp followed by cleavage between nucleosomes to yield 200 bp fragments.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/24396"^^xsd:anyURI) +AnnotationAssertion( "GO:0008178") +AnnotationAssertion( "DNA fragmentation") +AnnotationAssertion(Annotation( "GOC:mtg_apoptosis") "chromatinolysis") +AnnotationAssertion( "DNA catabolic process during apoptosis") +AnnotationAssertion( "DNA catabolism during apoptosis") +AnnotationAssertion(Annotation( "GOC:cjm") Annotation( "GOC:dph") Annotation( "GOC:tb") "DNA fragmentation involved in apoptotic nuclear change") +AnnotationAssertion( "endonucleolytic DNA catabolic process involved in apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006309") +AnnotationAssertion(rdfs:comment "DNA fragmentation in response to apoptotic signals is achieved through the activity of apoptotic nucleases. In human, these include DNA fragmentation factor (DFF) or caspase-activated DNase (CAD) and endonuclease G (Endo G) (reviewed in PMID:15723341). Caution is needed when apoptotic DNA laddering assays show presence of fragmented DNA. A positive assay may simply reflect the end point of a whole apoptotic process. Unless clear experimental evidence is available to show that a gene product is directly involved in fragmenting DNA, please do not annotate to GO:0006309 'apoptotic DNA fragmentation' and consider annotating instead to a more upstream process such as, e.g., GO:0042981 'regulation of apoptotic process', GO:0006915 'apoptotic process', GO:0097190 'apoptotic signaling pathway'. Also, note that gene products involved in compartmentalization of apoptotic nucleases and in activation or repression of their enzymatic activity should be annotated to the regulation term GO:1902510 'regulation of apoptotic DNA fragmentation' or to one of its children (see PMID:15723341).") +AnnotationAssertion(rdfs:label "apoptotic DNA fragmentation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (DNA recombination) + +AnnotationAssertion(Annotation( "ISBN:0198506732") "Any process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Interchromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006310") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "DNA recombination") +SubClassOf( ) + +# Class: (chromatin organization) + +AnnotationAssertion(Annotation( "PMID:20404130") "The assembly or remodeling of chromatin composed of DNA complexed with histones, other associated proteins, and sometimes RNA.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/22130"^^xsd:anyURI) +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/23549"^^xsd:anyURI) +AnnotationAssertion( "GO:0006333") +AnnotationAssertion( "GO:0006336") +AnnotationAssertion( "GO:0016568") +AnnotationAssertion( "GO:0031497") +AnnotationAssertion( "GO:0034724") +AnnotationAssertion( "chromatin maintenance") +AnnotationAssertion(Annotation( "GOC:mah") "chromatin organisation") +AnnotationAssertion(Annotation( "GOC:mah") "establishment of chromatin architecture") +AnnotationAssertion(Annotation( "GOC:mah") "establishment or maintenance of chromatin architecture") +AnnotationAssertion( "DNA replication-independent chromatin assembly") +AnnotationAssertion( "DNA replication-independent chromatin organization") +AnnotationAssertion( "DNA replication-independent nucleosome organisation") +AnnotationAssertion( "DNA replication-independent nuclesome assembly") +AnnotationAssertion( "chromatin assembly") +AnnotationAssertion( "transcription-coupled nucleosome assembly") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "chromatin assembly or disassembly") +AnnotationAssertion( "chromatin assembly/disassembly") +AnnotationAssertion( "chromatin modification") +AnnotationAssertion( "GO:0006325") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "chromatin organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (RNA catabolic process) + +AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage.") +AnnotationAssertion( "RNA breakdown") +AnnotationAssertion( "RNA catabolism") +AnnotationAssertion( "RNA degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006401") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "RNA catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (RNA localization) + +AnnotationAssertion(Annotation( "GOC:ai") "A process in which RNA is transported to, or maintained in, a specific location.") +AnnotationAssertion(Annotation( "GOC:mah") "RNA localisation") +AnnotationAssertion( "establishment and maintenance of RNA localization") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006403") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "RNA localization") +SubClassOf( ) + +# Class: (RNA import into nucleus) + +AnnotationAssertion(Annotation( "GOC:ma") "The import of RNA from the cytoplasm to the nucleus.") +AnnotationAssertion( "RNA import into cell nucleus") +AnnotationAssertion( "RNA transport from cytoplasm to nucleus") +AnnotationAssertion( "RNA-nucleus import") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006404") +AnnotationAssertion(rdfs:label "RNA import into nucleus") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (RNA export from nucleus) + +AnnotationAssertion(Annotation( "GOC:ma") "The directed movement of RNA from the nucleus to the cytoplasm.") +AnnotationAssertion( "RNA export from cell nucleus") +AnnotationAssertion( "RNA export out of nucleus") +AnnotationAssertion( "RNA transport from nucleus to cytoplasm") +AnnotationAssertion( "RNA-nucleus export") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006405") +AnnotationAssertion(rdfs:label "RNA export from nucleus") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + # Class: (translation) AnnotationAssertion(Annotation( "GOC:go_curators") "The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome.") @@ -30353,6 +55250,7 @@ AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "translation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) @@ -30405,6 +55303,74 @@ AnnotationAssertion(rdfs:label "tran SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (regulation of translation) + +AnnotationAssertion(Annotation( "GOC:isa_complete") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA.") +AnnotationAssertion( "GO:0006445") +AnnotationAssertion( "regulation of protein anabolism") +AnnotationAssertion( "regulation of protein biosynthesis") +AnnotationAssertion( "regulation of protein formation") +AnnotationAssertion( "regulation of protein synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006417") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "regulation of translation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of translational initiation) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of translational initiation.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006446") +AnnotationAssertion(rdfs:label "regulation of translational initiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (regulation of translational elongation) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate, extent or accuracy of translational elongation.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006448") +AnnotationAssertion(rdfs:label "regulation of translational elongation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (regulation of translational termination) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of translational termination.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006449") +AnnotationAssertion(rdfs:label "regulation of translational termination") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (protein phosphorylation) + +AnnotationAssertion(Annotation( "GOC:hb") "The process of introducing a phosphate group on to a protein.") +AnnotationAssertion(Annotation( "GOC:bf") "protein amino acid phosphorylation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006468") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "protein phosphorylation") +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of protein kinase activity) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of protein kinase activity.") +AnnotationAssertion( "down regulation of protein kinase activity") +AnnotationAssertion( "down-regulation of protein kinase activity") +AnnotationAssertion( "downregulation of protein kinase activity") +AnnotationAssertion( "inhibition of protein kinase activity") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006469") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "negative regulation of protein kinase activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + # Class: (proteolysis) AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:mah") "The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.") @@ -30420,6 +55386,28 @@ AnnotationAssertion(rdfs:comment "Th AnnotationAssertion(rdfs:label "proteolysis") SubClassOf( ) +# Class: (glycoprotein catabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide.") +AnnotationAssertion( "glycoprotein breakdown") +AnnotationAssertion( "glycoprotein catabolism") +AnnotationAssertion( "glycoprotein degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006516") +AnnotationAssertion(rdfs:label "glycoprotein catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (peptide metabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways involving peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another.") +AnnotationAssertion( "peptide metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006518") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "peptide metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (amino acid metabolic process) AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving amino acids, carboxylic acids containing one or more amino groups.") @@ -30439,10 +55427,23 @@ AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "amino acid metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ) +# Class: (regulation of cellular amino acid metabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amino acids.") +AnnotationAssertion( "regulation of amino acid metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006521") +AnnotationAssertion(rdfs:label "regulation of cellular amino acid metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + # Class: (glutamate metabolic process) AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways involving glutamate, the anion of 2-aminopentanedioic acid.") @@ -30453,9 +55454,45 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0006536") AnnotationAssertion(rdfs:label "glutamate metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) +# Class: (glutamate biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways resulting in the formation of glutamate, the anion of 2-aminopentanedioic acid.") +AnnotationAssertion( "glutamate anabolism") +AnnotationAssertion( "glutamate biosynthesis") +AnnotationAssertion( "glutamate formation") +AnnotationAssertion( "glutamate synthesis") +AnnotationAssertion( "glutamic acid biosynthesis") +AnnotationAssertion( "glutamic acid biosynthetic process") +AnnotationAssertion( "glutamate biosynthesis, using glutamate dehydrogenase (NAD(P)+)") +AnnotationAssertion( "glutamate biosynthesis, using glutamate synthase (NADPH)") +AnnotationAssertion( "glutamate biosynthetic process, using glutamate dehydrogenase (NAD(P)+)") +AnnotationAssertion( "glutamate biosynthetic process, using glutamate synthase (NADPH)") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006537") +AnnotationAssertion(rdfs:label "glutamate biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (glutamate catabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways resulting in the breakdown of glutamate, the anion of 2-aminopentanedioic acid.") +AnnotationAssertion( "GO:0019459") +AnnotationAssertion( "glutamate breakdown") +AnnotationAssertion( "glutamate catabolism") +AnnotationAssertion( "glutamate degradation") +AnnotationAssertion( "glutamic acid catabolic process") +AnnotationAssertion( "glutamic acid catabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "glutamate deamidation") +AnnotationAssertion( "GO:0006538") +AnnotationAssertion(rdfs:label "glutamate catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + # Class: (cellular modified amino acid metabolic process) AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways involving compounds derived from amino acids, organic acids containing one or more amino substituents.") @@ -30471,6 +55508,7 @@ AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "cellular modified amino acid metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) @@ -30494,7 +55532,6 @@ AnnotationAssertion( "GO:0006581") AnnotationAssertion(rdfs:label "acetylcholine catabolic process") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) # Class: (catecholamine metabolic process) @@ -30503,9 +55540,22 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0006584") AnnotationAssertion(rdfs:label "catecholamine metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) +# Class: (indolalkylamine metabolic process) + +AnnotationAssertion(Annotation( "GOC:curators") "The chemical reactions and pathways involving indolalkylamines, indole or indole derivatives containing a primary, secondary, or tertiary amine group.") +AnnotationAssertion( "indolamine metabolic process") +AnnotationAssertion( "indolamine metabolism") +AnnotationAssertion( "indolalkylamine metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006586") +AnnotationAssertion(rdfs:label "indolalkylamine metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + # Class: (thyroid hormone generation) AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0716720094") "The formation of either of the compounds secreted by the thyroid gland, mainly thyroxine and triiodothyronine. This is achieved by the iodination and joining of tyrosine molecules to form the precursor thyroglobin, proteolysis of this precursor gives rise to the thyroid hormones.") @@ -30515,6 +55565,43 @@ AnnotationAssertion(rdfs:comment "No AnnotationAssertion(rdfs:label "thyroid hormone generation") SubClassOf( ) +# Class: (protein import into nucleus) + +AnnotationAssertion(Annotation( "GOC:jl") "The directed movement of a protein from the cytoplasm to the nucleus.") +AnnotationAssertion(Annotation( "GOC:mah") "establishment of protein localization to nucleus") +AnnotationAssertion( "protein import into cell nucleus") +AnnotationAssertion( "protein nucleus import") +AnnotationAssertion( "protein transport from cytoplasm to nucleus") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006606") +AnnotationAssertion(rdfs:label "protein import into nucleus") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (protein export from nucleus) + +AnnotationAssertion(Annotation( "GOC:jl") "The directed movement of a protein from the nucleus into the cytoplasm.") +AnnotationAssertion( "GO:0097349") +AnnotationAssertion( "protein export from cell nucleus") +AnnotationAssertion( "protein export out of nucleus") +AnnotationAssertion( "protein transport from nucleus to cytoplasm") +AnnotationAssertion( "protein-nucleus export") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:al") "copper-induced protein export from nucleus") +AnnotationAssertion( "GO:0006611") +AnnotationAssertion(rdfs:label "protein export from nucleus") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (vacuolar protein processing) + +AnnotationAssertion(Annotation( "GOC:mah") "Protein processing that takes place in the vacuole. Most protein processing in the vacuole represents proteolytic cleavage of precursors to form active enzymes.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "vacuolar protein maturation") +AnnotationAssertion( "vacuolar proteolysis") +AnnotationAssertion( "GO:0006624") +AnnotationAssertion(rdfs:label "vacuolar protein processing") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + # Class: (lipid metabolic process) AnnotationAssertion(Annotation( "GOC:ma") "The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids.") @@ -30535,10 +55622,149 @@ AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "lipid metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ) +# Class: (fatty acid metabolic process) + +AnnotationAssertion(Annotation( "ISBN:0198547684") "The chemical reactions and pathways involving fatty acids, aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis.") +AnnotationAssertion( "Wikipedia:Fatty_acid_metabolism") +AnnotationAssertion( "fatty acid metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006631") +AnnotationAssertion(rdfs:label "fatty acid metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (fatty acid biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes.") +AnnotationAssertion( "GO:0000037") +AnnotationAssertion( "MetaCyc:FASYN-INITIAL-PWY") +AnnotationAssertion( "MetaCyc:PWY-4381") +AnnotationAssertion( "MetaCyc:PWY-5156") +AnnotationAssertion( "Wikipedia:Fatty_acid_synthesis") +AnnotationAssertion( "fatty acid anabolism") +AnnotationAssertion( "fatty acid biosynthesis") +AnnotationAssertion( "fatty acid formation") +AnnotationAssertion( "fatty acid synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006633") +AnnotationAssertion(rdfs:label "fatty acid biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (membrane lipid metabolic process) + +AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways involving membrane lipids, any lipid found in or associated with a biological membrane.") +AnnotationAssertion( "membrane lipid metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006643") +AnnotationAssertion(rdfs:label "membrane lipid metabolic process") +SubClassOf( ) + +# Class: (phospholipid metabolic process) + +AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving phospholipids, any lipid containing phosphoric acid as a mono- or diester.") +AnnotationAssertion( "phospholipid metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006644") +AnnotationAssertion(rdfs:label "phospholipid metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (glycolipid metabolic process) + +AnnotationAssertion(Annotation( "ISBN:0198547684") "The chemical reactions and pathways involving glycolipids, a class of 1,2-di-O-acylglycerols joined at oxygen 3 by a glycosidic linkage to a carbohydrate part (usually a mono-, di- or tri-saccharide). Some substances classified as bacterial glycolipids have the sugar group acylated by one or more fatty acids and the glycerol group may be absent.") +AnnotationAssertion( "glycolipid metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006664") +AnnotationAssertion(rdfs:label "glycolipid metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (sphingolipid metabolic process) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).") +AnnotationAssertion( "sphingolipid metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006665") +AnnotationAssertion(rdfs:label "sphingolipid metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (ceramide metabolic process) + +AnnotationAssertion(Annotation( "ISBN:0198547684") "The chemical reactions and pathways involving ceramides, any N-acylated sphingoid.") +AnnotationAssertion( "ceramide metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006672") +AnnotationAssertion(rdfs:label "ceramide metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (glycosylceramide metabolic process) + +AnnotationAssertion(Annotation( "GOC:ai") Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving glycosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of a monosaccharide (or derivative) by a ceramide group.") +AnnotationAssertion( "glycosylceramide metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006677") +AnnotationAssertion(rdfs:label "glycosylceramide metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (galactosylceramide metabolic process) + +AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways involving galactosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of galactose by a ceramide group.") +AnnotationAssertion( "galactosylceramide metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006681") +AnnotationAssertion(rdfs:label "galactosylceramide metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (galactosylceramide biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways resulting in the formation of galactosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of galactose by a ceramide group.") +AnnotationAssertion( "galactosylceramide anabolism") +AnnotationAssertion( "galactosylceramide biosynthesis") +AnnotationAssertion( "galactosylceramide formation") +AnnotationAssertion( "galactosylceramide synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006682") +AnnotationAssertion(rdfs:label "galactosylceramide biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (galactosylceramide catabolic process) + +AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways resulting in the breakdown of galactosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of galactose by a ceramide group.") +AnnotationAssertion( "galactosylceramide breakdown") +AnnotationAssertion( "galactosylceramide catabolism") +AnnotationAssertion( "galactosylceramide degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006683") +AnnotationAssertion(rdfs:label "galactosylceramide catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (glycosphingolipid metabolic process) + +AnnotationAssertion(Annotation( "ISBN:0198547684") "The chemical reactions and pathways involving glycosphingolipids, any compound with residues of sphingoid and at least one monosaccharide.") +AnnotationAssertion( "glycosphingolipid metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006687") +AnnotationAssertion(rdfs:label "glycosphingolipid metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (glycosphingolipid biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways resulting in the formation of glycosphingolipid, a compound with residues of sphingoid and at least one monosaccharide.") +AnnotationAssertion( "glycosphingolipid anabolism") +AnnotationAssertion( "glycosphingolipid biosynthesis") +AnnotationAssertion( "glycosphingolipid formation") +AnnotationAssertion( "glycosphingolipid synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006688") +AnnotationAssertion(rdfs:label "glycosphingolipid biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (steroid biosynthetic process) AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus; includes de novo formation and steroid interconversion by modification.") @@ -30551,6 +55777,7 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0006694") AnnotationAssertion(rdfs:label "steroid biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ) @@ -30565,6 +55792,7 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0006699") AnnotationAssertion(rdfs:label "bile acid biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ) @@ -30580,11 +55808,24 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0006700") AnnotationAssertion(rdfs:label "C21-steroid hormone biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) +# Class: (progesterone biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:jl") Annotation( "http://www.cogsci.princeton.edu/") "The chemical reactions and pathways resulting in the formation of progesterone, a steroid hormone produced in the ovary which prepares and maintains the uterus for pregnancy. Also found in plants.") +AnnotationAssertion( "progesterone anabolism") +AnnotationAssertion( "progesterone biosynthesis") +AnnotationAssertion( "progesterone formation") +AnnotationAssertion( "progesterone synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006701") +AnnotationAssertion(rdfs:label "progesterone biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (glucocorticoid biosynthetic process) AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of glucocorticoids, hormonal C21 corticosteroids synthesized from cholesterol.") @@ -30595,6 +55836,7 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0006704") AnnotationAssertion(rdfs:label "glucocorticoid biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (mineralocorticoid biosynthetic process) @@ -30606,8 +55848,134 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0006705") AnnotationAssertion(rdfs:label "mineralocorticoid biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (steroid catabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways resulting in the breakdown of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.") +AnnotationAssertion( "steroid breakdown") +AnnotationAssertion( "steroid catabolism") +AnnotationAssertion( "steroid degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006706") +AnnotationAssertion(rdfs:label "steroid catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (progesterone catabolic process) + +AnnotationAssertion(Annotation( "GOC:jl") Annotation( "http://www.cogsci.princeton.edu/") "The chemical reactions and pathways resulting in the breakdown of progesterone, a steroid hormone produced in the ovary which prepares and maintains the uterus for pregnancy. Also found in plants.") +AnnotationAssertion( "progesterone breakdown") +AnnotationAssertion( "progesterone catabolism") +AnnotationAssertion( "progesterone degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006709") +AnnotationAssertion(rdfs:label "progesterone catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (mineralocorticoid catabolic process) + +AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of mineralocorticoids, hormonal C21 corticosteroids synthesized from cholesterol.") +AnnotationAssertion( "mineralocorticoid breakdown") +AnnotationAssertion( "mineralocorticoid catabolism") +AnnotationAssertion( "mineralocorticoid degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006712") +AnnotationAssertion(rdfs:label "mineralocorticoid catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (glucocorticoid catabolic process) + +AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of glucocorticoids, hormonal C21 corticosteroids synthesized from cholesterol.") +AnnotationAssertion( "glucocorticoid breakdown") +AnnotationAssertion( "glucocorticoid catabolism") +AnnotationAssertion( "glucocorticoid degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006713") +AnnotationAssertion(rdfs:label "glucocorticoid catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (sesquiterpenoid metabolic process) + +AnnotationAssertion(Annotation( "ISBN:0198547684") "The chemical reactions and pathways involving sesquiterpenoid compounds, terpenoids with three isoprene units.") +AnnotationAssertion( "sesquiterpenoid metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006714") +AnnotationAssertion(rdfs:label "sesquiterpenoid metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (juvenile hormone metabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198547684") "The chemical reactions and pathways involving juvenile hormones, the three sesquiterpenoid derivatives that function to maintain the larval state of insects at molting and that may be required for other processes, e.g. oogenesis.") +AnnotationAssertion( "juvenile hormone metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006716") +AnnotationAssertion(rdfs:label "juvenile hormone metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (juvenile hormone biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198547684") "The chemical reactions and pathways resulting in the formation of juvenile hormones, the three sesquiterpenoid derivatives that function to maintain the larval state of insects at molting and that may be required for other processes, e.g. oogenesis.") +AnnotationAssertion( "juvenile hormone anabolism") +AnnotationAssertion( "juvenile hormone biosynthesis") +AnnotationAssertion( "juvenile hormone formation") +AnnotationAssertion( "juvenile hormone synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006718") +AnnotationAssertion(rdfs:label "juvenile hormone biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (juvenile hormone catabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198547684") "The chemical reactions and pathways resulting in the breakdown of juvenile hormones, the three sesquiterpenoid derivatives that function to maintain the larval state of insects at molting and that may be required for other processes, e.g. oogenesis.") +AnnotationAssertion( "juvenile hormone breakdown") +AnnotationAssertion( "juvenile hormone catabolism") +AnnotationAssertion( "juvenile hormone degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006719") +AnnotationAssertion(rdfs:label "juvenile hormone catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (isoprenoid metabolic process) + +AnnotationAssertion(Annotation( "ISBN:0198547684") "The chemical reactions and pathways involving isoprenoid compounds, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues.") +AnnotationAssertion( "GO:0016096") +AnnotationAssertion( "isoprenoid metabolism") +AnnotationAssertion( "polyisoprenoid metabolic process") +AnnotationAssertion( "polyisoprenoid metabolism") +AnnotationAssertion( "polyterpene metabolic process") +AnnotationAssertion( "polyterpene metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006720") +AnnotationAssertion(rdfs:label "isoprenoid metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (terpenoid metabolic process) + +AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving terpenoids, any member of a class of compounds characterized by an isoprenoid chemical structure and including derivatives with various functional groups.") +AnnotationAssertion( "terpenoid metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006721") +AnnotationAssertion(rdfs:label "terpenoid metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (cuticle hydrocarbon biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways resulting in the formation of hydrocarbons that make up the cuticle, the outer layer of some animals and plants, which acts to prevent water loss.") +AnnotationAssertion( "cuticle hydrocarbon anabolism") +AnnotationAssertion( "cuticle hydrocarbon biosynthesis") +AnnotationAssertion( "cuticle hydrocarbon formation") +AnnotationAssertion( "cuticle hydrocarbon synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006723") +AnnotationAssertion(rdfs:label "cuticle hydrocarbon biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + # Class: (cellular aromatic compound metabolic process) AnnotationAssertion(Annotation( "GOC:ai") Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving aromatic compounds, any organic compound characterized by one or more planar rings, each of which contains conjugated double bonds and delocalized pi electrons, as carried out by individual cells.") @@ -30618,8 +55986,109 @@ AnnotationAssertion( "GO:0006725") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "cellular aromatic compound metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (nucleoside phosphate metabolic process) + +AnnotationAssertion(Annotation( "GOC:mah") "The chemical reactions and pathways involving any phosphorylated nucleoside.") +AnnotationAssertion( "nucleoside phosphate metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006753") +AnnotationAssertion(rdfs:label "nucleoside phosphate metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (ATP biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.") +AnnotationAssertion( "GO:0006758") +AnnotationAssertion( "GO:0006759") +AnnotationAssertion( "ATP anabolism") +AnnotationAssertion( "ATP biosynthesis") +AnnotationAssertion( "ATP formation") +AnnotationAssertion( "ATP synthesis") +AnnotationAssertion( "ATP regeneration") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006754") +AnnotationAssertion(rdfs:label "ATP biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (porphyrin-containing compound metabolic process) + +AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0198506732") Annotation( "Wikipedia:Porphyrin#Natural_formation") "The chemical reactions and pathways involving any member of a large group of derivatives or analogs of porphyrin. Porphyrins consists of a ring of four pyrrole nuclei linked each to the next at their alpha positions through a methine group.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "porphyrin metabolic process") +AnnotationAssertion( "porphyrin metabolism") +AnnotationAssertion( "GO:0006778") +AnnotationAssertion(rdfs:label "porphyrin-containing compound metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (porphyrin-containing compound biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0198506732") Annotation( "Wikipedia:Porphyrin#Natural_formation") "The chemical reactions and pathways resulting in the formation of any member of a large group of derivatives or analogs of porphyrin. Porphyrin consists of a ring of four pyrrole nuclei linked each to the next at their alpha positions through a methine group.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "porphyrin anabolism") +AnnotationAssertion( "porphyrin biosynthesis") +AnnotationAssertion( "porphyrin biosynthetic process") +AnnotationAssertion( "porphyrin formation") +AnnotationAssertion( "porphyrin synthesis") +AnnotationAssertion( "GO:0006779") +AnnotationAssertion(rdfs:label "porphyrin-containing compound biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (porphyrin-containing compound catabolic process) + +AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of any member of a large group of derivatives or analogs of porphyrin. Porphyrin consists of a ring of four pyrrole nuclei linked each to the next at their alpha positions through a methine group.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "porphyrin breakdown") +AnnotationAssertion( "porphyrin catabolic process") +AnnotationAssertion( "porphyrin catabolism") +AnnotationAssertion( "porphyrin degradation") +AnnotationAssertion( "GO:0006787") +AnnotationAssertion(rdfs:label "porphyrin-containing compound catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (sulfur compound metabolic process) + +AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways involving the nonmetallic element sulfur or compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione.") +AnnotationAssertion( "Wikipedia:Sulfur_metabolism") +AnnotationAssertion( "sulfur metabolism") +AnnotationAssertion( "sulphur metabolic process") +AnnotationAssertion( "sulphur metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006790") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "sulfur compound metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (phosphorus metabolic process) + +AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways involving the nonmetallic element phosphorus or compounds that contain phosphorus, usually in the form of a phosphate group (PO4).") +AnnotationAssertion( "phosphorus metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006793") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "phosphorus metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (phosphate-containing compound metabolic process) + +AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways involving the phosphate group, the anion or salt of any phosphoric acid.") +AnnotationAssertion( "phosphate metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "phosphate metabolic process") +AnnotationAssertion( "GO:0006796") +AnnotationAssertion(rdfs:label "phosphate-containing compound metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (nitrogen compound metabolic process) AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving organic or inorganic compounds that contain nitrogen.") @@ -30629,6 +56098,7 @@ AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "nitrogen compound metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (transport) @@ -30653,14 +56123,111 @@ AnnotationAssertion(rdfs:comment "No AnnotationAssertion(rdfs:label "transport") SubClassOf( ) +# Class: (monoatomic ion transport) + +AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of a monoatomic ion into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Monatomic ions (also called simple ions) are ions consisting of exactly one atom.") +AnnotationAssertion( "ion transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006811") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "monoatomic ion transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (monoatomic cation transport) + +AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of a monoatomic cation, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Monatomic cations (also called simple cations) are positively charged ions consisting of exactly one atom.") +AnnotationAssertion( "GO:0006819") +AnnotationAssertion( "GO:0015674") +AnnotationAssertion( "GO:0072512") +AnnotationAssertion( "cation transport") +AnnotationAssertion(Annotation( "GOC:mah") "di-, tri-valent inorganic cation transport") +AnnotationAssertion( "trivalent inorganic cation transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006812") +AnnotationAssertion(rdfs:label "monoatomic cation transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (sodium ion transport) + +AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion( "GO:0006834") +AnnotationAssertion( "GO:0016974") +AnnotationAssertion( "sodium/potassium transport") +AnnotationAssertion( "sodium transport") +AnnotationAssertion( "mitochondrial sodium/calcium ion exchange") +AnnotationAssertion( "sodium:calcium exchange") +AnnotationAssertion( "sodium:solute transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:mah") "sodium channel auxiliary protein activity") +AnnotationAssertion( "GO:0006814") +AnnotationAssertion(rdfs:label "sodium ion transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (calcium ion transport) + +AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of calcium (Ca) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion( "calcium transport") +AnnotationAssertion( "mitochondrial sodium/calcium ion exchange") +AnnotationAssertion( "sodium:calcium exchange") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006816") +AnnotationAssertion(rdfs:label "calcium ion transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (phosphate ion transport) + +AnnotationAssertion(Annotation( "GOC:krc") "The directed movement of phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "phosphate transport") +AnnotationAssertion( "GO:0006817") +AnnotationAssertion(rdfs:label "phosphate ion transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (iron ion transport) + +AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of iron (Fe) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2012-04-18T03:33:45Z") +AnnotationAssertion( "GO:0015681") +AnnotationAssertion( "GO:0015682") +AnnotationAssertion( "GO:0015684") +AnnotationAssertion( "GO:0033216") +AnnotationAssertion( "GO:0097286") +AnnotationAssertion( "iron transport") +AnnotationAssertion( "ferric ion import") +AnnotationAssertion( "ferric ion transport") +AnnotationAssertion( "ferric iron import") +AnnotationAssertion( "ferric iron transport") +AnnotationAssertion( "ferric iron uptake") +AnnotationAssertion( "ferrous ion transport") +AnnotationAssertion( "ferrous iron transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "iron ion import") +AnnotationAssertion( "GO:0006826") +AnnotationAssertion(rdfs:label "iron ion transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (water transport) AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of water (H2O) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0006833") AnnotationAssertion(rdfs:label "water transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (dicarboxylic acid transport) + +AnnotationAssertion(Annotation( "GOC:krc") "The directed movement of dicarboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion( "GO:0006841") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "sodium:dicarboxylate transport") +AnnotationAssertion( "GO:0006835") +AnnotationAssertion(rdfs:label "dicarboxylic acid transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (neurotransmitter transport) AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Neurotransmitters are any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell.") @@ -30679,6 +56246,61 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:0006837") AnnotationAssertion(rdfs:label "serotonin transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (acetate transport) + +AnnotationAssertion(Annotation( "GOC:krc") "The directed movement of acetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006846") +AnnotationAssertion(rdfs:label "acetate transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (plasma membrane acetate transport) + +AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of acetate across a plasma membrane.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006847") +AnnotationAssertion(rdfs:label "plasma membrane acetate transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (extracellular transport) + +AnnotationAssertion(Annotation( "GOC:go_curators") "The transport of substances that occurs outside cells.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006858") +AnnotationAssertion(rdfs:label "extracellular transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (extracellular amino acid transport) + +AnnotationAssertion(Annotation( "GOC:ai") "The directed extracellular movement of amino acids.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006860") +AnnotationAssertion(rdfs:label "extracellular amino acid transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (nucleotide transport) + +AnnotationAssertion(Annotation( "ISBN:0198506732") "The directed movement of a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate, into, out of or within a cell.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006862") +AnnotationAssertion(rdfs:label "nucleotide transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (purine nucleobase transport) + +AnnotationAssertion(Annotation( "ISBN:0198506732") "The directed movement of purine bases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion( "GO:0015852") +AnnotationAssertion(Annotation( "GOC:mah") "purine base transmembrane transport") +AnnotationAssertion(Annotation( "GOC:go_curators") "purine base transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:mah") "purine transmembrane transport") +AnnotationAssertion( "purine transport") +AnnotationAssertion( "GO:0006863") +AnnotationAssertion(rdfs:label "purine nucleobase transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (amino acid transport) @@ -30689,6 +56311,7 @@ AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "amino acid transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (lipid transport) @@ -30699,8 +56322,61 @@ AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "lipid transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (intracellular monoatomic ion homeostasis) + +AnnotationAssertion(Annotation( "GOC:mah") "A homeostatic process involved in the maintenance of a steady state level of monoatomic ions within a cell. Monatomic ions (also called simple ions) are ions consisting of exactly one atom.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/24455"^^xsd:anyURI) +AnnotationAssertion( "cellular ion homeostasis") +AnnotationAssertion( "cellular monoatomic ion homeostasis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006873") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "intracellular monoatomic ion homeostasis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (intracellular calcium ion homeostasis) + +AnnotationAssertion(Annotation( "GOC:ceb") Annotation( "GOC:mah") "A homeostatic process involved in the maintenance of a steady state level of calcium ions within a cell.") +AnnotationAssertion( "regulation of calcium ion concentration") +AnnotationAssertion( "cellular calcium ion homeostasis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006874") +AnnotationAssertion(rdfs:label "intracellular calcium ion homeostasis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (intracellular iron ion homeostasis) + +AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:mah") "A homeostatic process involved in the maintenance of a steady state level of iron ions within a cell.") +AnnotationAssertion( "iron homeostasis") +AnnotationAssertion( "cellular iron ion homeostasis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006879") +AnnotationAssertion(rdfs:label "intracellular iron ion homeostasis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (intracellular sodium ion homeostasis) + +AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:mah") "A homeostatic process involved in the maintenance of a steady state level of sodium ions within a cell.") +AnnotationAssertion( "cellular sodium ion homeostasis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006883") +AnnotationAssertion(rdfs:label "intracellular sodium ion homeostasis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (cell volume homeostasis) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:go_curators") Annotation( "GOC:tb") "Any process involved in maintaining the steady state of a cell's volume. The cell's volume refers to the three-dimensional space occupied by a cell.") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "regulation of cell volume") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006884") +AnnotationAssertion(rdfs:label "cell volume homeostasis") +SubClassOf( ) + # Class: (regulation of pH) AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:go_curators") Annotation( "GOC:tb") "Any process involved in the maintenance of an internal equilibrium of hydrogen ions, thereby modulating the internal pH, within an organism or cell.") @@ -30708,8 +56384,22 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:0006885") AnnotationAssertion(rdfs:label "regulation of pH") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (intracellular protein transport) + +AnnotationAssertion(Annotation( "GOC:mah") "The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell.") +AnnotationAssertion( "GO:0032779") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:al") "copper-induced intracellular protein transport") +AnnotationAssertion( "GO:0006886") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "intracellular protein transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (exocytosis) AnnotationAssertion(Annotation( "GOC:mah") Annotation( "ISBN:0716731363") Annotation( "PMID:22323285") "A process of secretion by a cell that results in the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle. Exocytosis can occur either by full fusion, when the vesicle collapses into the plasma membrane, or by a kiss-and-run mechanism that involves the formation of a transient contact, a pore, between a granule (for exemple of chromaffin cells) and the plasma membrane. The latter process most of the time leads to only partial secretion of the granule content. Exocytosis begins with steps that prepare vesicles for fusion with the membrane (tethering and docking) and ends when molecules are secreted from the cell.") @@ -30722,9 +56412,213 @@ AnnotationAssertion( "GO:0006887") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "exocytosis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (post-Golgi vesicle-mediated transport) + +AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:mah") "The directed movement of substances from the Golgi to other parts of the cell, including organelles and the plasma membrane, mediated by small transport vesicles.") +AnnotationAssertion( "post-Golgi transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006892") +AnnotationAssertion(rdfs:label "post-Golgi vesicle-mediated transport") +SubClassOf( ) + +# Class: (Golgi to plasma membrane transport) + +AnnotationAssertion(Annotation( "ISBN:0716731363") "The directed movement of substances from the Golgi to the plasma membrane in transport vesicles that move from the trans-Golgi network to the plasma membrane, where they fuse and release their contents by exocytosis.") +AnnotationAssertion( "Golgi to plasma membrane vesicle-mediated transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006893") +AnnotationAssertion(rdfs:label "Golgi to plasma membrane transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (Golgi to vacuole transport) + +AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of substances from the Golgi to the vacuole.") +AnnotationAssertion( "Golgi to vacuole vesicle-mediated transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006896") +AnnotationAssertion(rdfs:label "Golgi to vacuole transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (endocytosis) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "ISBN:0198506732") Annotation( "ISBN:0716731363") Annotation( "Wikipedia:Endocytosis") "A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a part of the plasma membrane to form a new membrane-bounded vesicle.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/24907"^^xsd:anyURI) +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/25268"^^xsd:anyURI) +AnnotationAssertion( "GO:0016193") +AnnotationAssertion( "GO:0016196") +AnnotationAssertion( "GO:0098701") +AnnotationAssertion( "Wikipedia:Endocytosis") +AnnotationAssertion( "endocytic import into cell") +AnnotationAssertion( "vesicle endocytosis") +AnnotationAssertion( "plasma membrane invagination") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "nonselective vesicle endocytosis") +AnnotationAssertion( "GO:0006897") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "endocytosis") +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (vesicle budding from membrane) + +AnnotationAssertion(Annotation( "GOC:jid") Annotation( "GOC:tb") "The evagination of a membrane, resulting in formation of a vesicle.") +AnnotationAssertion( "jl") +AnnotationAssertion( "2013-12-19T15:26:17Z") +AnnotationAssertion( "GO:0006902") +AnnotationAssertion( "GO:1902591") +AnnotationAssertion( "membrane evagination") +AnnotationAssertion( "vesicle biosynthesis") +AnnotationAssertion( "vesicle formation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "nonselective vesicle assembly") +AnnotationAssertion(Annotation( "GOC:TermGenie") "single organism membrane budding") +AnnotationAssertion( "single-organism membrane budding") +AnnotationAssertion( "vesicle budding") +AnnotationAssertion( "GO:0006900") +AnnotationAssertion(rdfs:label "vesicle budding from membrane") +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (vesicle targeting) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "PMID:17335816") "The process in which vesicles are directed to specific destination membranes. Targeting involves coordinated interactions among cytoskeletal elements (microtubules or actin filaments), motor proteins, molecules at the vesicle membrane and target membrane surfaces, and vesicle cargo.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006903") +AnnotationAssertion(rdfs:label "vesicle targeting") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (vesicle fusion) + +AnnotationAssertion(Annotation( "GOC:jid") "Fusion of the membrane of a transport vesicle with its target membrane.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006906") +AnnotationAssertion(rdfs:label "vesicle fusion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (phagocytosis) + +AnnotationAssertion(Annotation( "ISBN:0198506732") "A vesicle-mediated transport process that results in the engulfment of external particulate material by phagocytes and their delivery to the lysosome. The particles are initially contained within phagocytic vacuoles (phagosomes), which then fuse with primary lysosomes to effect digestion of the particles.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/24907"^^xsd:anyURI) +AnnotationAssertion( ) +AnnotationAssertion( "Wikipedia:Phagocytosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006909") +AnnotationAssertion(rdfs:label "phagocytosis") +SubClassOf( ) +SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses( ObjectSomeValuesFrom( )) + +# Class: (nucleocytoplasmic transport) + +AnnotationAssertion(Annotation( "GOC:go_curators") "The directed movement of molecules between the nucleus and the cytoplasm.") +AnnotationAssertion( "GO:0000063") +AnnotationAssertion( "nucleocytoplasmic shuttling") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006913") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:comment "Note that transport through the nuclear pore complex is not transmembrane because the nuclear membrane is a double membrane, and is not traversed.") +AnnotationAssertion(rdfs:label "nucleocytoplasmic transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (apoptotic process) + +AnnotationAssertion(Annotation( "GOC:cjm") Annotation( "GOC:dhl") Annotation( "GOC:ecd") Annotation( "GOC:go_curators") Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:tb") Annotation( "ISBN:0198506732") Annotation( "PMID:18846107") Annotation( "PMID:21494263") "A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( "GO:0006917") +AnnotationAssertion( "GO:0008632") +AnnotationAssertion( "cell suicide") +AnnotationAssertion( "cellular suicide") +AnnotationAssertion( "Wikipedia:Apoptosis") +AnnotationAssertion(Annotation( "GOC:sl") "apoptotic cell death") +AnnotationAssertion( "apoptotic programmed cell death") +AnnotationAssertion( "programmed cell death by apoptosis") +AnnotationAssertion( "activation of apoptosis") +AnnotationAssertion( "apoptosis") +AnnotationAssertion( "apoptosis signaling") +AnnotationAssertion(Annotation( "GOC:add") "apoptotic program") +AnnotationAssertion( "type I programmed cell death") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "apoptosis activator activity") +AnnotationAssertion( "caspase-dependent programmed cell death") +AnnotationAssertion( "commitment to apoptosis") +AnnotationAssertion( "induction of apoptosis") +AnnotationAssertion( "induction of apoptosis by p53") +AnnotationAssertion( "signaling (initiator) caspase activity") +AnnotationAssertion( "GO:0006915") +AnnotationAssertion(rdfs:label "apoptotic process") +SubClassOf( ) +SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) +SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) +SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectAllValuesFrom( )) +DisjointClasses( ObjectSomeValuesFrom( )) +DisjointClasses( ObjectSomeValuesFrom( )) + +# Class: (cellular component disassembly involved in execution phase of apoptosis) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mah") Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:tb") "The breakdown of structures such as organelles, proteins, or other macromolecular structures during apoptosis.") +AnnotationAssertion( "cellular component disassembly involved in apoptotic process") +AnnotationAssertion( "disassembly of cell structures") +AnnotationAssertion( "cellular component disassembly involved in apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006921") +AnnotationAssertion(rdfs:label "cellular component disassembly involved in execution phase of apoptosis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (inflammatory cell apoptotic process) + +AnnotationAssertion(Annotation( "GOC:jl") Annotation( "GOC:mtg_apoptosis") "Any apoptotic process in an inflammatory cell, any cell participating in the inflammatory response to a foreign substance e.g. neutrophil, macrophage.") +AnnotationAssertion( "apoptosis of inflammatory cells") +AnnotationAssertion( "inflammatory cell programmed cell death by apoptosis") +AnnotationAssertion( "killing of inflammatory cells") +AnnotationAssertion( "programmed cell death of inflammatory cells by apoptosis") +AnnotationAssertion( "programmed cell death, inflammatory cells") +AnnotationAssertion( "inflammatory cell apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006925") +AnnotationAssertion(rdfs:label "inflammatory cell apoptotic process") +SubClassOf( ) + +# Class: (chemotaxis) + +AnnotationAssertion(Annotation( "ISBN:0198506732") "The directed movement of a motile cell or organism, or the directed growth of a cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).") +AnnotationAssertion( "Wikipedia:Chemotaxis") +AnnotationAssertion( "taxis in response to chemical stimulus") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006935") +AnnotationAssertion(rdfs:label "chemotaxis") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (muscle contraction) AnnotationAssertion(Annotation( "GOC:ef") Annotation( "GOC:mtg_muscle") Annotation( "ISBN:0198506732") "A process in which force is generated within muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis.") @@ -30736,6 +56630,15 @@ AnnotationAssertion(rdfs:label "musc SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (regulation of muscle contraction) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of muscle contraction.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006937") +AnnotationAssertion(rdfs:label "regulation of muscle contraction") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + # Class: (smooth muscle contraction) AnnotationAssertion(Annotation( "GOC:ef") Annotation( "GOC:jl") Annotation( "GOC:mtg_muscle") Annotation( "ISBN:0198506732") "A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Smooth muscle differs from striated muscle in the much higher actin/myosin ratio, the absence of conspicuous sarcomeres and the ability to contract to a much smaller fraction of its resting length.") @@ -30743,8 +56646,18 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0006939") AnnotationAssertion(rdfs:label "smooth muscle contraction") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (regulation of smooth muscle contraction) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of smooth muscle contraction.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006940") +AnnotationAssertion(rdfs:label "regulation of smooth muscle contraction") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + # Class: (striated muscle contraction) AnnotationAssertion(Annotation( "GOC:jl") Annotation( "GOC:mtg_muscle") Annotation( "ISBN:0198506732") "A process in which force is generated within striated muscle tissue, resulting in the shortening of the muscle. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Striated muscle is a type of muscle in which the repeating units (sarcomeres) of the contractile myofibrils are arranged in registry throughout the cell, resulting in transverse or oblique striations observable at the level of the light microscope.") @@ -30755,6 +56668,27 @@ AnnotationAssertion(rdfs:label "stri SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (regulation of striated muscle contraction) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of striated muscle contraction.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006942") +AnnotationAssertion(rdfs:label "regulation of striated muscle contraction") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (syncytium formation) + +AnnotationAssertion(Annotation( "ISBN:0198506732") "The formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane. Syncytia are normally derived from single cells that fuse or fail to complete cell division.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0006949") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "syncytium formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + # Class: (response to stress) AnnotationAssertion(Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).") @@ -30818,6 +56752,415 @@ AnnotationAssertion( "humoral immune response") SubClassOf( ) +# Class: (organelle organization) + +AnnotationAssertion(Annotation( "GOC:mah") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an organelle within a cell. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.") +AnnotationAssertion( "jl") +AnnotationAssertion( "2013-12-19T15:25:51Z") +AnnotationAssertion( "GO:1902589") +AnnotationAssertion( "organelle organisation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "single organism organelle organization") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:jl") Annotation( "GOC:mah") "organelle organization and biogenesis") +AnnotationAssertion( "single-organism organelle organization") +AnnotationAssertion( "GO:0006996") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "organelle organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (nucleus organization) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:ems") Annotation( "GOC:jl") Annotation( "GOC:mah") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nucleus.") +AnnotationAssertion( "GO:0048287") +AnnotationAssertion( "nuclear organisation") +AnnotationAssertion( "nuclear organization") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "nuclear morphology") +AnnotationAssertion(Annotation( "GOC:mah") "nuclear organization and biogenesis") +AnnotationAssertion(Annotation( "GOC:mah") "nucleus organization and biogenesis") +AnnotationAssertion( "GO:0006997") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "nucleus organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (nuclear envelope organization) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:ems") Annotation( "GOC:jl") Annotation( "GOC:mah") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear envelope.") +AnnotationAssertion(Annotation( "GOC:mah") "nuclear envelope organisation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:mah") "nuclear envelope organization and biogenesis") +AnnotationAssertion( "GO:0006998") +AnnotationAssertion(rdfs:label "nuclear envelope organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (nucleolus organization) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GOC:jl") Annotation( "GOC:mah") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nucleolus.") +AnnotationAssertion( "nucleolus organisation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:mah") "nucleolus organization and biogenesis") +AnnotationAssertion( "GO:0007000") +AnnotationAssertion(rdfs:label "nucleolus organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (plasma membrane organization) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:jl") Annotation( "GOC:mah") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the plasma membrane.") +AnnotationAssertion( "plasma membrane organisation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:mah") "plasma membrane organization and biogenesis") +AnnotationAssertion( "GO:0007009") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "plasma membrane organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cytoskeleton organization) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:jl") Annotation( "GOC:mah") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures.") +AnnotationAssertion( "cytoskeleton organisation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:mah") "cytoskeletal organization and biogenesis") +AnnotationAssertion( "cytoskeletal regulator activity") +AnnotationAssertion(Annotation( "GOC:mah") "cytoskeleton organization and biogenesis") +AnnotationAssertion( "GO:0007010") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "cytoskeleton organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (actin filament organization) + +AnnotationAssertion(Annotation( "GOC:mah") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments. Includes processes that control the spatial distribution of actin filaments, such as organizing filaments into meshworks, bundles, or other structures, as by cross-linking.") +AnnotationAssertion( "actin filament organisation") +AnnotationAssertion( "regulation of actin filament localization") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0007015") +AnnotationAssertion(rdfs:label "actin filament organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (microtubule-based process) + +AnnotationAssertion(Annotation( "GOC:mah") "Any cellular process that depends upon or alters the microtubule cytoskeleton, that part of the cytoskeleton comprising microtubules and their associated proteins.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/19809"^^xsd:anyURI) +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0007017") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "microtubule-based process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (microtubule-based movement) + +AnnotationAssertion(Annotation( "GOC:cjm") Annotation( "ISBN:0815316194") "A microtubule-based process that results in the movement of organelles, other microtubules, or other cellular components. Examples include motor-driven movement along microtubules and movement driven by polymerization or depolymerization of microtubules.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0007018") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "microtubule-based movement") +SubClassOf( ) + +# Class: (microtubule depolymerization) + +AnnotationAssertion(Annotation( "ISBN:0815316194") "The removal of tubulin heterodimers from one or both ends of a microtubule.") +AnnotationAssertion( "microtubule disassembly") +AnnotationAssertion( "microtubule shortening") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "microtubule catastrophe") +AnnotationAssertion( "microtubule depolymerization during nuclear congression") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0007019") +AnnotationAssertion(rdfs:label "microtubule depolymerization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (microtubule nucleation) + +AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0815316194") Annotation( "PMID:12517712") "The process in which tubulin alpha-beta heterodimers begin aggregation to form an oligomeric tubulin structure (a microtubule seed). Microtubule nucleation is the initiating step in the formation of a microtubule in the absence of any existing microtubules ('de novo' microtubule formation).") +AnnotationAssertion( "Wikipedia:Microtubule_nucleation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0007020") +AnnotationAssertion(rdfs:label "microtubule nucleation") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (negative regulation of microtubule depolymerization) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "ISBN:0815316194") "Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule depolymerization; prevention of depolymerization of a microtubule can result from binding by 'capping' at the plus end (e.g. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing drug such as taxol.") +AnnotationAssertion( "down regulation of microtubule depolymerization") +AnnotationAssertion( "down-regulation of microtubule depolymerization") +AnnotationAssertion( "downregulation of microtubule depolymerization") +AnnotationAssertion( "microtubule stabilization") +AnnotationAssertion( "negative regulation of microtubule disassembly") +AnnotationAssertion( "inhibition of microtubule depolymerization") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "microtubule rescue") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "negative regulation of microtubule catastrophe") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0007026") +AnnotationAssertion(rdfs:label "negative regulation of microtubule depolymerization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of axonemal microtubule depolymerization) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of the depolymerization of the specialized microtubules of the axoneme.") +AnnotationAssertion( "axonemal microtubule stabilization") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") "negative regulation of microtubule depolymerization in axoneme") +AnnotationAssertion( "GO:0007027") +AnnotationAssertion(rdfs:label "negative regulation of axonemal microtubule depolymerization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (cytoplasm organization) + +AnnotationAssertion(Annotation( "GOC:curators") Annotation( "GOC:dph") Annotation( "GOC:jl") Annotation( "GOC:mah") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the cytoplasm. The cytoplasm is all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.") +AnnotationAssertion( "cytoplasm organisation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:mah") "cytoplasm organization and biogenesis") +AnnotationAssertion( "GO:0007028") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "cytoplasm organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (Golgi organization) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:jl") Annotation( "GOC:mah") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the Golgi apparatus.") +AnnotationAssertion( "Golgi apparatus organization") +AnnotationAssertion( "Golgi organisation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:mah") "Golgi organization and biogenesis") +AnnotationAssertion( "GO:0007030") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "Golgi organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (vacuole organization) + +AnnotationAssertion(Annotation( "GOC:mah") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vacuole.") +AnnotationAssertion( "GO:0044086") +AnnotationAssertion( "vacuole organisation") +AnnotationAssertion(Annotation( "GOC:mah") "vacuolar assembly") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:mah") "vacuole biogenesis") +AnnotationAssertion(Annotation( "GOC:mah") "vacuole organization and biogenesis") +AnnotationAssertion( "GO:0007033") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "vacuole organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (vacuolar transport) + +AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of substances into, out of or within a vacuole.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0007034") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "vacuolar transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (vacuolar calcium ion homeostasis) + +AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:mah") "Any process involved in the maintenance of an internal steady state of calcium ions in the vacuole or between a vacuole and its surroundings.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0007036") +AnnotationAssertion(rdfs:label "vacuolar calcium ion homeostasis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (protein catabolic process in the vacuole) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:vw") "The chemical reactions and pathways resulting in the breakdown of a protein in the vacuole, usually by the action of vacuolar proteases.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "vacuolar protein breakdown") +AnnotationAssertion( "vacuolar protein catabolic process") +AnnotationAssertion( "vacuolar protein catabolism") +AnnotationAssertion( "vacuolar protein degradation") +AnnotationAssertion( "GO:0007039") +AnnotationAssertion(rdfs:label "protein catabolic process in the vacuole") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (lysosome organization) + +AnnotationAssertion(Annotation( "GOC:mah") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lysosome. A lysosome is a cytoplasmic, membrane-bounded organelle that is found in most animal cells and that contains a variety of hydrolases.") +AnnotationAssertion( "lysosome organisation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:mah") "lysosome organization and biogenesis") +AnnotationAssertion( "GO:0007040") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "lysosome organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (lysosomal transport) + +AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of substances into, out of or within a lysosome.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0007041") +AnnotationAssertion(rdfs:label "lysosomal transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (cell-cell junction assembly) + +AnnotationAssertion(Annotation( "GOC:ai") "The aggregation, arrangement and bonding together of a set of components to form a junction between cells.") +AnnotationAssertion( "intercellular junction assembly") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0007043") +AnnotationAssertion(rdfs:label "cell-cell junction assembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (cell cycle) + +AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "GOC:mtg_cell_cycle") "The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division.") +AnnotationAssertion( "Wikipedia:Cell_cycle") +AnnotationAssertion( "cell-division cycle") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0007049") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "cell cycle") +SubClassOf( ) + +# Class: (chromosome segregation) + +AnnotationAssertion(Annotation( "GOC:jl") Annotation( "GOC:mah") Annotation( "GOC:mtg_cell_cycle") Annotation( "GOC:vw") "The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. In eukaryotes, chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles.") +AnnotationAssertion( "Wikipedia:Chromosome_segregation") +AnnotationAssertion( "chromosome division") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "chromosome transmission") +AnnotationAssertion( "GO:0007059") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "chromosome segregation") +SubClassOf( ) +SubClassOf( ) + +# Class: (mitotic chromosome condensation) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "ISBN:0815316194") "The cell cycle process in which chromatin structure is compacted prior to and during mitosis in eukaryotic cells.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0007076") +AnnotationAssertion(rdfs:label "mitotic chromosome condensation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (mitotic nuclear membrane disassembly) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "PMID:32848252") "The mitotic cell cycle process in which the controlled partial or complete breakdown of the nuclear membranes during occurs during mitosis.") +AnnotationAssertion( "NEB") +AnnotationAssertion( "local NEB") +AnnotationAssertion( "nuclear envelope breakdown") +AnnotationAssertion( "mitotic nuclear envelope breakdown") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "mitotic nuclear envelope catabolism") +AnnotationAssertion( "mitotic nuclear envelope degradation") +AnnotationAssertion( "mitotic nuclear envelope disassembly") +AnnotationAssertion( "GO:0007077") +AnnotationAssertion(rdfs:label "mitotic nuclear membrane disassembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of mitotic nuclear division) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of mitosis.") +AnnotationAssertion( "regulation of mitosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0007088") +AnnotationAssertion(rdfs:label "regulation of mitotic nuclear division") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (nuclear migration) + +AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of the nucleus to a specific location within a cell.") +AnnotationAssertion( "GO:0040023") +AnnotationAssertion( "establishment of position of nucleus") +AnnotationAssertion( "nuclear movement") +AnnotationAssertion( "nuclear positioning") +AnnotationAssertion( "nucleus migration") +AnnotationAssertion( "nucleus positioning") +AnnotationAssertion( "positioning of nucleus") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "establishment of cell nucleus localization") +AnnotationAssertion( "establishment of localization of nucleus") +AnnotationAssertion(Annotation( "GOC:mah") "establishment of nucleus localisation") +AnnotationAssertion( "establishment of nucleus localization") +AnnotationAssertion( "GO:0007097") +AnnotationAssertion(rdfs:label "nuclear migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (endomitotic cell cycle) + +AnnotationAssertion(Annotation( "GOC:curators") Annotation( "GOC:dos") Annotation( "GOC:expert_vm") "A mitotic cell cycle in which chromosomes are replicated and sister chromatids separate, but spindle formation, nuclear membrane breakdown and nuclear division do not occur, resulting in an increased number of chromosomes in the cell.") +AnnotationAssertion( "Wikipedia:Mitosis#Endomitosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "endomitosis") +AnnotationAssertion( "GO:0007113") +AnnotationAssertion(rdfs:comment "Note that this term should not be confused with 'abortive mitotic cell cycle ; GO:0033277'. Although abortive mitosis is sometimes called endomitosis, GO:0033277 refers to a process in which a mitotic spindle forms and chromosome separation begins.") +AnnotationAssertion(rdfs:label "endomitotic cell cycle") +SubClassOf( ) + +# Class: (meiosis II) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mah") Annotation( "ISBN:0198547684") "The second nuclear division of meiosis, in which the two chromatids in each chromosome are separated, resulting in four daughter nuclei from the two nuclei produced in meiosis II.") +AnnotationAssertion( "Wikipedia:Meiosis#Meiosis_II") +AnnotationAssertion( "meiosis II nuclear division") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0007135") +AnnotationAssertion(rdfs:label "meiosis II") +SubClassOf( ) +SubClassOf( ) + +# Class: (male meiotic nuclear division) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mah") Annotation( "GOC:vw") "A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the male germline.") +AnnotationAssertion( ) +AnnotationAssertion( "male nuclear division") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "male meiosis") +AnnotationAssertion( "GO:0007140") +AnnotationAssertion(rdfs:label "male meiotic nuclear division") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses( ObjectSomeValuesFrom( )) + +# Class: (male meiosis II) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mah") "A cell cycle process comprising the steps by which a cell progresses through male meiosis II, the second meiotic division in the male germline.") +AnnotationAssertion( "male meiosis II nuclear division") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0007142") +AnnotationAssertion(rdfs:label "male meiosis II") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf( ) + # Class: (female meiotic nuclear division) AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:ems") Annotation( "GOC:mah") Annotation( "GOC:vw") "A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the female germline.") @@ -30828,11 +57171,22 @@ AnnotationAssertion( "GO:0007143") AnnotationAssertion(rdfs:comment "Note that female germ lines can be found in female or hermaphroditic organisms, so this term can be used to annotate gene products from hermaphrodites such as those of C. elegans. See also the biological process term 'meiotic nuclear division; GO:0140013'.") AnnotationAssertion(rdfs:label "female meiotic nuclear division") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) DisjointClasses( ObjectSomeValuesFrom( )) +# Class: (female meiosis II) + +AnnotationAssertion(Annotation( "GOC:mah") "The cell cycle process in which the second meiotic division occurs in the female germline.") +AnnotationAssertion( "female meiosis II nuclear division") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0007147") +AnnotationAssertion(rdfs:label "female meiosis II") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf( ) + # Class: (cell communication) AnnotationAssertion(Annotation( "GOC:mah") "Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.") @@ -30844,6 +57198,239 @@ AnnotationAssertion( "cell communication") SubClassOf( ) +# Class: (cell adhesion) + +AnnotationAssertion(Annotation( "GOC:hb") Annotation( "GOC:pf") "The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.") +AnnotationAssertion( "dos") +AnnotationAssertion( "2014-04-15T15:59:10Z") +AnnotationAssertion( "GO:0098602") +AnnotationAssertion( "Wikipedia:Cell_adhesion") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "cell adhesion molecule activity") +AnnotationAssertion( "single organism cell adhesion") +AnnotationAssertion( "GO:0007155") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "cell adhesion") +SubClassOf( ) + +# Class: (leukocyte cell-cell adhesion) + +AnnotationAssertion(Annotation( "GOC:go_curators") "The attachment of a leukocyte to another cell via adhesion molecules.") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( "leukocyte adhesion") +AnnotationAssertion( "leukocyte cell adhesion") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0007159") +AnnotationAssertion(rdfs:label "leukocyte cell-cell adhesion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) +SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) +SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) +SubClassOf( ObjectAllValuesFrom( )) +SubClassOf( ObjectAllValuesFrom( )) +DisjointClasses( ObjectSomeValuesFrom( )) +DisjointClasses( ObjectSomeValuesFrom( )) + +# Class: (negative regulation of cell adhesion) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of cell adhesion.") +AnnotationAssertion( "down regulation of cell adhesion") +AnnotationAssertion( "down-regulation of cell adhesion") +AnnotationAssertion( "downregulation of cell adhesion") +AnnotationAssertion( "inhibition of cell adhesion") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "cell adhesion receptor inhibitor activity") +AnnotationAssertion( "GO:0007162") +AnnotationAssertion(rdfs:label "negative regulation of cell adhesion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (establishment or maintenance of cell polarity) + +AnnotationAssertion(Annotation( "GOC:mah") "Any cellular process that results in the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns.") +AnnotationAssertion( "GO:0030012") +AnnotationAssertion( "GO:0030467") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:vw") "cell polarity") +AnnotationAssertion( "establishment and/or maintenance of cell polarity") +AnnotationAssertion( "establishment and/or maintenance of cell polarization") +AnnotationAssertion( "GO:0007163") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "establishment or maintenance of cell polarity") +SubClassOf( ) + +# Class: (signal transduction) + +AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "GOC:mtg_signaling_feb11") "The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.") +AnnotationAssertion( "GO:0023014") +AnnotationAssertion( "GO:0023015") +AnnotationAssertion( "GO:0023016") +AnnotationAssertion( "GO:0023033") +AnnotationAssertion( "GO:0023045") +AnnotationAssertion( "Wikipedia:Signal_transduction") +AnnotationAssertion( "signal transduction by cis-phosphorylation") +AnnotationAssertion( "signal transduction by conformational transition") +AnnotationAssertion( "signal transduction by protein phosphorylation") +AnnotationAssertion( "signal transduction by trans-phosphorylation") +AnnotationAssertion( "signaling cascade") +AnnotationAssertion( "signalling cascade") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "signaling pathway") +AnnotationAssertion(Annotation( "GOC:mah") "signalling pathway") +AnnotationAssertion( "GO:0007165") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:comment "Note that signal transduction is defined broadly to include a ligand interacting with a receptor, downstream signaling steps and a response being triggered. A change in form of the signal in every step is not necessary. Note that in many cases the end of this process is regulation of the initiation of transcription. Note that specific transcription factors may be annotated to this term, but core/general transcription machinery such as RNA polymerase should not.") +AnnotationAssertion(rdfs:label "signal transduction") +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cell surface receptor signaling pathway) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:mah") Annotation( "GOC:pr") Annotation( "GOC:signaling") "The series of molecular signals initiated by activation of a receptor on the surface of a cell. The pathway begins with binding of an extracellular ligand to a cell surface receptor, or for receptors that signal in the absence of a ligand, by ligand-withdrawal or the activity of a constitutively active receptor. The pathway ends with regulation of a downstream cellular process, e.g. transcription.") +AnnotationAssertion( "cell surface receptor linked signal transduction") +AnnotationAssertion(Annotation( "GOC:bf") "cell surface receptor linked signaling pathway") +AnnotationAssertion(Annotation( "GOC:mah") "cell surface receptor linked signalling pathway") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0007166") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "cell surface receptor signaling pathway") +SubClassOf( ) + +# Class: (enzyme-linked receptor protein signaling pathway) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:signaling") Annotation( "ISBN:0815316194") "The series of molecular signals initiated by an extracellular ligand binding to a receptor on the surface of the target cell, where the receptor possesses catalytic activity or is closely associated with an enzyme such as a protein kinase, and ending with the regulation of a downstream cellular process, e.g. transcription.") +AnnotationAssertion( "enzyme linked receptor protein signaling pathway") +AnnotationAssertion( "enzyme linked receptor protein signalling pathway") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0007167") +AnnotationAssertion(rdfs:label "enzyme-linked receptor protein signaling pathway") +SubClassOf( ) + +# Class: (transmembrane receptor protein tyrosine kinase signaling pathway) + +AnnotationAssertion(Annotation( "GOC:ceb") Annotation( "GOC:signaling") "The series of molecular signals initiated by an extracellular ligand binding to a receptor on the surface of the target cell where the receptor possesses tyrosine kinase activity, and ending with the regulation of a downstream cellular process, e.g. transcription.") +AnnotationAssertion( "transmembrane receptor protein tyrosine kinase signalling pathway") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0007169") +AnnotationAssertion(rdfs:label "transmembrane receptor protein tyrosine kinase signaling pathway") +SubClassOf( ) + +# Class: (G protein-coupled receptor signaling pathway) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:mah") Annotation( "PMID:16902576") Annotation( "PMID:24568158") Annotation( "Wikipedia:G_protein-coupled_receptor") "The series of molecular signals initiated by a ligand binding to its receptor, in which the activated receptor promotes the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, and ends with regulation of a downstream cellular process. The pathway can start from the plasma membrane, Golgi or nuclear membrane.") +AnnotationAssertion( "GO:0038042") +AnnotationAssertion( "G protein coupled receptor protein signaling pathway") +AnnotationAssertion( "G protein coupled receptor protein signalling pathway") +AnnotationAssertion( "G-protein coupled receptor protein signal transduction") +AnnotationAssertion(Annotation( "GOC:bf") "G-protein coupled receptor protein signaling pathway") +AnnotationAssertion( "G-protein coupled receptor signalling pathway") +AnnotationAssertion( "G-protein-coupled receptor protein signalling pathway") +AnnotationAssertion( "GPCR signaling pathway") +AnnotationAssertion( "GPCR signalling pathway") +AnnotationAssertion(Annotation( "GOC:bf") "G-protein coupled receptor signaling pathway via GPCR dimer") +AnnotationAssertion( "dimeric G-protein coupled receptor signaling pathway") +AnnotationAssertion(Annotation( "GOC:mah") "dimeric G-protein coupled receptor signalling pathway") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0007186") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "G protein-coupled receptor signaling pathway") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (serotonin receptor signaling pathway) + +AnnotationAssertion(Annotation( "GOC:mah") "The series of molecular signals generated as a consequence of a serotonin receptor binding to one of its physiological ligands.") +AnnotationAssertion( "serotonin receptor signalling pathway") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0007210") +AnnotationAssertion(rdfs:label "serotonin receptor signaling pathway") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (G protein-coupled acetylcholine receptor signaling pathway) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "ISBN:0815316194") "A G protein-coupled receptor signaling pathway initiated by a ligand binding to an acetylcholine receptor on the surface of a target cell, and ends with regulation of a downstream cellular process, e.g. transcription.") +AnnotationAssertion( "G-protein coupled acetylcholine receptor signaling pathway") +AnnotationAssertion( "acetylcholine receptor signalling, muscarinic pathway") +AnnotationAssertion(Annotation( "GOC:bf") "muscarinic acetylcholine receptor signaling pathway") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0007213") +AnnotationAssertion(rdfs:label "G protein-coupled acetylcholine receptor signaling pathway") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (gamma-aminobutyric acid signaling pathway) + +AnnotationAssertion(Annotation( "GOC:mah") "The series of molecular signals generated by the binding of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms, to its receptor on the surface of a target cell.") +AnnotationAssertion( "4-aminobutanoate signaling pathway") +AnnotationAssertion( "4-aminobutanoate signalling pathway") +AnnotationAssertion( "4-aminobutyrate signaling pathway") +AnnotationAssertion( "4-aminobutyrate signalling pathway") +AnnotationAssertion( "GABA signaling pathway") +AnnotationAssertion( "GABA signalling pathway") +AnnotationAssertion( "gamma-aminobutyric acid signalling pathway") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0007214") +AnnotationAssertion(rdfs:label "gamma-aminobutyric acid signaling pathway") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (glutamate receptor signaling pathway) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:signaling") Annotation( "PMID:9131252") "The series of molecular signals initiated by the binding of glutamate to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.") +AnnotationAssertion(Annotation( "GOC:bf") "glutamate signaling pathway") +AnnotationAssertion( "glutamate signalling pathway") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0007215") +AnnotationAssertion(rdfs:label "glutamate receptor signaling pathway") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (G protein-coupled glutamate receptor signaling pathway) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:signaling") Annotation( "PMID:9131252") "A G protein-coupled receptor signaling pathway initiated by glutamate binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process.") +AnnotationAssertion( "G-protein coupled glutamate receptor signaling pathway") +AnnotationAssertion(Annotation( "GOC:bf") "metabotropic glutamate receptor signaling pathway") +AnnotationAssertion( "metabotropic glutamate receptor signalling pathway") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0007216") +AnnotationAssertion(rdfs:label "G protein-coupled glutamate receptor signaling pathway") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (neuropeptide signaling pathway) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "ISBN:0815316194") "A G protein-coupled receptor signaling pathway initiated by a neuropeptide binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process.") +AnnotationAssertion( ) +AnnotationAssertion( "neuropeptide signalling pathway") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0007218") +AnnotationAssertion(rdfs:label "neuropeptide signaling pathway") +SubClassOf( ) +SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses( ObjectSomeValuesFrom( )) + # Class: (cell-cell signaling) AnnotationAssertion(Annotation( "GOC:dos") Annotation( "GOC:mah") "Any process that mediates the transfer of information from one cell to another. This process includes signal transduction in the receiving cell and, where applicable, release of a ligand and any processes that actively facilitate its transport and presentation to the receiving cell. Examples include signaling via soluble ligands, via cell adhesion molecules and via gap junctions.") @@ -30887,6 +57474,36 @@ SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (synaptic transmission, cholinergic) + +AnnotationAssertion(Annotation( "GOC:dos") Annotation( "Wikipedia:Cholinergic") "The vesicular release of acetylcholine from a presynapse, across a chemical synapse, the subsequent activation of dopamine receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.") +AnnotationAssertion( "cholinergic synaptic transmission") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0007271") +AnnotationAssertion(rdfs:label "synaptic transmission, cholinergic") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (ensheathment of neurons) + +AnnotationAssertion(Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:tb") "The process in which glial cells envelop neuronal cell bodies and/or axons to form an insulating layer. This can take the form of myelinating or non-myelinating ensheathment.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "ionic insulation of neurons by glial cells") +AnnotationAssertion( "GO:0007272") +AnnotationAssertion(rdfs:label "ensheathment of neurons") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (neuromuscular synaptic transmission) + +AnnotationAssertion(Annotation( "GOC:dos") Annotation( "GOC:jl") Annotation( "MeSH:D009435") "The process of synaptic transmission from a neuron to a muscle, across a synapse.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0007274") +AnnotationAssertion(rdfs:label "neuromuscular synaptic transmission") +SubClassOf( ) + # Class: (multicellular organism development) AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:ems") Annotation( "GOC:isa_complete") Annotation( "GOC:tb") "The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).") @@ -30898,6 +57515,7 @@ AnnotationAssertion( ) AnnotationAssertion(rdfs:comment "Note that this term was 'developmental process'.") AnnotationAssertion(rdfs:label "multicellular organism development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ) @@ -30927,6 +57545,7 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0007281") AnnotationAssertion(rdfs:label "germ cell development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ) @@ -30943,6 +57562,28 @@ AnnotationAssertion(rdfs:label "sper SubClassOf( ) SubClassOf( ) +# Class: (spermatogonial cell division) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:pr") Annotation( "ISBN:0879694238") "The mitotic divisions of the primary spermatogonial cell (a primordial male germ cell) to form secondary spermatogonia (primary spermatocytes).") +AnnotationAssertion( "spermatogonium division") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0007284") +AnnotationAssertion(rdfs:comment "See also the Cell Ontology terms 'spermatogonium ; CL:0000020' and 'primary spermatocyte ; CL:0000656'.") +AnnotationAssertion(rdfs:label "spermatogonial cell division") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (primary spermatocyte growth) + +AnnotationAssertion(Annotation( "GOC:jid") Annotation( "ISBN:0879694238") "The phase of growth and gene expression that male germ cells undergo as they enter the spermatocyte stage. The cells grow in volume and transcribe most of the gene products needed for the morphological events that follow meiosis.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0007285") +AnnotationAssertion(rdfs:label "primary spermatocyte growth") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (spermatid development) AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:go_curators") "The process whose specific outcome is the progression of a spermatid over time, from its formation to the mature structure.") @@ -30952,9 +57593,32 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0007286") AnnotationAssertion(rdfs:label "spermatid development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (sperm axoneme assembly) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:cilia") Annotation( "ISBN:0198547684") "The assembly and organization of the sperm flagellar axoneme, the bundle of microtubules and associated proteins that forms the core of the eukaryotic sperm flagellum, and is responsible for movement.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0007288") +AnnotationAssertion(rdfs:label "sperm axoneme assembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (spermatid nucleus differentiation) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:dph") Annotation( "GOC:jl") Annotation( "GOC:mah") "The specialization of the spermatid nucleus during the development of a spermatid into a mature male gamete competent for fertilization.") +AnnotationAssertion( "spermatid nuclear differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0007289") +AnnotationAssertion(rdfs:comment "See also the Cell Ontology term 'spermatid ; CL:0000018'.") +AnnotationAssertion(rdfs:label "spermatid nucleus differentiation") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (female gamete generation) AnnotationAssertion(Annotation( "GOC:dph") Annotation( "ISBN:0198506732") "Generation of the female gamete; specialised haploid cells produced by meiosis and along with a male gamete takes part in sexual reproduction.") @@ -30963,6 +57627,109 @@ AnnotationAssertion( "female gamete generation") SubClassOf( ) +# Class: (germarium-derived egg chamber formation) + +AnnotationAssertion(Annotation( "GOC:mtg_sensu") Annotation( "ISBN:0879694238") "Construction of a stage-1 egg chamber in the anterior part of the germarium, from the progeny of germ-line and somatic stem cells. An example of this is found in Drosophila melanogaster.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0007293") +AnnotationAssertion(rdfs:label "germarium-derived egg chamber formation") +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectAllValuesFrom( )) + +# Class: (follicle cell of egg chamber migration) + +AnnotationAssertion(Annotation( "GOC:mtg_sensu") Annotation( "PMID:10822261") "The directed movement of an ovarian follicle cell that takes place during oogenesis. During egg chamber formation, follicle cells migrate to envelop the germ-line cysts and move in between cysts. At stage 10B, follicle cells migrate centripetally between the nurse cells and the oocyte, enclosing the anterior of the egg. An example of this is found in Drosophila melanogaster.") +AnnotationAssertion( "follicle cell migration") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0007297") +AnnotationAssertion(rdfs:label "follicle cell of egg chamber migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectAllValuesFrom( )) + +# Class: (chorion-containing eggshell formation) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:mtg_sensu") "The construction of a chorion-containing eggshell. An example of this is found in Drosophila melanogaster.") +AnnotationAssertion( "eggshell formation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0007304") +AnnotationAssertion(rdfs:label "chorion-containing eggshell formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (vitelline membrane formation involved in chorion-containing eggshell formation) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:mtg_sensu") "Construction of the vitelline membrane portion of a chorion-containing eggshell. An example of this is found in Drosophila melanogaster.") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "vitelline membrane formation in chorion-containing eggshell") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0007305") +AnnotationAssertion(rdfs:label "vitelline membrane formation involved in chorion-containing eggshell formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (egg chorion assembly) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_sensu") Annotation( "GOC:tb") Annotation( "ISBN:0879694238") Annotation( "PMID:24804966") "Construction of the chorion portion of the egg, which is a protective, noncellular membrane that surrounds the eggs of various animals including insects and fish.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/22603"^^xsd:anyURI) +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "eggshell chorion formation") +AnnotationAssertion( "insect chorion formation") +AnnotationAssertion( "GO:0007306") +AnnotationAssertion(rdfs:label "egg chorion assembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (oocyte construction) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:ems") Annotation( "GOC:mtg_sensu") Annotation( "GOC:tb") Annotation( "ISBN:0198506732") "The synthesis, deposition, and organization of the materials in a cell of an ovary; where the cell can then undergo meiosis and form an ovum. An example of this is found in Drosophila melanogaster.") +AnnotationAssertion( "GO:0048110") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "oocyte arrangement") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0007308") +AnnotationAssertion(rdfs:label "oocyte construction") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (oocyte axis specification) + +AnnotationAssertion(Annotation( "GOC:mtg_sensu") Annotation( "ISBN:0879694238") "The establishment, maintenance and elaboration of an axis in the oocyte. An example of this is found in Drosophila melanogaster.") +AnnotationAssertion( "GO:0048111") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "oocyte axis determination") +AnnotationAssertion( "GO:0007309") +AnnotationAssertion(rdfs:label "oocyte axis specification") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (oocyte anterior/posterior axis specification) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_sensu") Annotation( "GOC:tb") Annotation( "ISBN:0879694238") "Polarization of the oocyte along its anterior-posterior axis. An example of this is found in Drosophila melanogaster.") +AnnotationAssertion( "GO:0048112") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "oocyte anterior/posterior axis determination") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0007314") +AnnotationAssertion(rdfs:label "oocyte anterior/posterior axis specification") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (insemination) AnnotationAssertion(Annotation( "ISBN:0582227089") "The introduction of semen or sperm into the genital tract of a female.") @@ -30975,6 +57742,74 @@ SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (single fertilization) + +AnnotationAssertion(Annotation( "GOC:ems") Annotation( "GOC:mtg_sensu") "The union of male and female gametes to form a zygote.") +AnnotationAssertion( ) +AnnotationAssertion( "biological_process") +AnnotationAssertion( "zygote biosynthesis") +AnnotationAssertion( "zygote formation") +AnnotationAssertion( "GO:0007338") +AnnotationAssertion(rdfs:label "single fertilization") +SubClassOf( ) +SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) +SubClassOf( ObjectAllValuesFrom( )) +DisjointClasses( ObjectSomeValuesFrom( )) + +# Class: (egg activation) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "PMID:9630751") "The process in which the egg becomes metabolically active, initiates protein and DNA synthesis and undergoes structural changes to its cortex and/or cytoplasm.") +AnnotationAssertion( "Wikipedia:Egg_activation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0007343") +AnnotationAssertion(rdfs:label "egg activation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (regulation of mitotic cell cycle) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:go_curators") Annotation( "GOC:tb") "Any process that modulates the rate or extent of progress through the mitotic cell cycle.") +AnnotationAssertion( "mitotic cell cycle modulation") +AnnotationAssertion( "mitotic cell cycle regulation") +AnnotationAssertion( "modulation of mitotic cell cycle progression") +AnnotationAssertion( "regulation of mitotic cell cycle progression") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "regulation of progression through mitotic cell cycle") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "mitotic cell cycle regulator") +AnnotationAssertion( "GO:0007346") +AnnotationAssertion(rdfs:label "regulation of mitotic cell cycle") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (blastoderm segmentation) + +AnnotationAssertion(Annotation( "ISBN:0879694238") Annotation( "http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm") "The hierarchical steps resulting in the progressive subdivision of the anterior/posterior axis of the embryo.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0007350") +AnnotationAssertion(rdfs:label "blastoderm segmentation") +SubClassOf( ) +SubClassOf( ) + +# Class: (tripartite regional subdivision) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:isa_complete") Annotation( "ISBN:0879694238") Annotation( "http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm") "Subdivision of the embryo along the anterior/posterior axis into anterior, posterior and terminal regions.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0007351") +AnnotationAssertion(rdfs:label "tripartite regional subdivision") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (zygotic determination of anterior/posterior axis, embryo) + +AnnotationAssertion(Annotation( "ISBN:0879694238") Annotation( "http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm") "The specification of the anterior/posterior axis of the embryo by products of genes expressed in the zygote; exemplified in insects by the gap genes, pair rule genes and segment polarity gene cascade.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0007354") +AnnotationAssertion(rdfs:label "zygotic determination of anterior/posterior axis, embryo") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + # Class: (gastrulation) AnnotationAssertion(Annotation( "GOC:curators") Annotation( "ISBN:9780878933846") "A complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals. The details of gastrulation vary from species to species, but usually result in the formation of the three primary germ layers, ectoderm, mesoderm and endoderm.") @@ -30989,12 +57824,36 @@ SubClassOf( ObjectSomeValuesFrom( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (amnioserosa formation) + +AnnotationAssertion(Annotation( "ISBN:0879694238") "Formation of the amnioserosa, an epithelium that occupies a hole in the embryonic dorsal epidermis. This occurs by the transformation of a narrow strip of cells at the dorsal midline of the blastoderm from columnar to squamous cells, accompanied by a lateral shift.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0007378") +AnnotationAssertion(rdfs:label "amnioserosa formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (pattern specification process) + +AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "GOC:isa_complete") Annotation( "ISBN:0521436125") "Any developmental process that results in the creation of defined areas or spaces within an organism to which cells respond and eventually are instructed to differentiate.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "pattern biosynthesis") +AnnotationAssertion( "pattern formation") +AnnotationAssertion( "GO:0007389") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "pattern specification process") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (ectoderm development) AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "The process whose specific outcome is the progression of the ectoderm over time, from its formation to the mature structure. In animal embryos, the ectoderm is the outer germ layer of the embryo, formed during gastrulation.") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0007398") AnnotationAssertion(rdfs:label "ectoderm development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) # Class: (nervous system development) @@ -31005,16 +57864,351 @@ AnnotationAssertion( "GO:0007399") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "nervous system development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (neuroblast proliferation) + +AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:mtg_sensu") Annotation( "GOC:sart") "The expansion of a neuroblast population by cell division. A neuroblast is any cell that will divide and give rise to a neuron.") +AnnotationAssertion( "GO:0043349") +AnnotationAssertion( "GO:0043350") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0007405") +AnnotationAssertion(rdfs:label "neuroblast proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectAllValuesFrom( )) + +# Class: (negative regulation of neuroblast proliferation) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of the proliferation of neuroblasts.") +AnnotationAssertion( "down regulation of neuroblast proliferation") +AnnotationAssertion( "down-regulation of neuroblast proliferation") +AnnotationAssertion( "downregulation of neuroblast proliferation") +AnnotationAssertion( "suppression of neuroblast proliferation") +AnnotationAssertion( "inhibition of neuroblast proliferation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0007406") +AnnotationAssertion(rdfs:label "negative regulation of neuroblast proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (neuroblast activation) + +AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "GOC:mtg_sensu") "A change in the morphology or behavior of a neuroblast resulting from exposure to an activating factor such as a cellular or soluble ligand.") +AnnotationAssertion( "GO:0043351") +AnnotationAssertion( "GO:0043352") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0007407") +AnnotationAssertion(rdfs:label "neuroblast activation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectAllValuesFrom( )) + +# Class: (axonogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GOC:pg") Annotation( "GOC:pr") Annotation( "ISBN:0198506732") "De novo generation of a long process of a neuron, including the terminal branched region. Refers to the morphogenesis or creation of shape or form of the developing axon, which carries efferent (outgoing) action potentials from the cell body towards target cells.") +AnnotationAssertion( "GO:0007410") +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "PMID:23517308") "axon morphogenesis") +AnnotationAssertion(Annotation( ) "neuron long process generation") +AnnotationAssertion( "axon growth") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0007409") +AnnotationAssertion(rdfs:comment "Note that 'axonogenesis' differs from 'axon development' in that the latter also covers other processes, such as axon regeneration (regrowth after loss or damage, not necessarily of the whole axon).") +AnnotationAssertion(rdfs:label "axonogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (synapse assembly) + +AnnotationAssertion(Annotation( "GOC:mah") "The aggregation, arrangement and bonding together of a set of components to form a synapse. This process ends when the synapse is mature (functional).") +AnnotationAssertion( "Wikipedia:Synaptogenesis") +AnnotationAssertion(Annotation( "GOC:mah") "synapse biogenesis") +AnnotationAssertion(Annotation( "GOC:mah") "synaptogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0007416") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "synapse assembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (central nervous system development) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:jid") Annotation( "ISBN:0582227089") "The process whose specific outcome is the progression of the central nervous system over time, from its formation to the mature structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.") +AnnotationAssertion( "Wikipedia:Neural_development") +AnnotationAssertion( "CNS development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0007417") +AnnotationAssertion(rdfs:label "central nervous system development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (ventral midline development) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:go_curators") Annotation( "PMID:12075342") "The process whose specific outcome is the progression of the ventral midline over time, from its formation to the mature structure. In protostomes (such as insects, snails and worms) as well as deuterostomes (vertebrates), the midline is an embryonic region that functions in patterning of the adjacent nervous tissue. The ventral midline in insects is a cell population extending along the ventral surface of the embryo and is the region from which cells detach to form the ventrally located nerve cords. In vertebrates, the midline is originally located dorsally. During development, it folds inwards and becomes the ventral part of the dorsally located neural tube and is then called the ventral midline, or floor plate.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0007418") +AnnotationAssertion(rdfs:label "ventral midline development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (ventral cord development) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:go_curators") Annotation( "http://users.rcn.com/jkimball.ma.ultranet/BiologyPages/S/Spemann.html") "The process whose specific outcome is the progression of the ventral cord over time, from its formation to the mature structure. The ventral cord is one of the distinguishing traits of the central nervous system of all arthropods (such as insects, crustaceans and arachnids) as well as many other invertebrates, such as the annelid worms.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0007419") +AnnotationAssertion(rdfs:label "ventral cord development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (brain development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GOC:tb") Annotation( "UBERON:0000955") "The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0007420") +AnnotationAssertion(rdfs:label "brain development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (peripheral nervous system development) + +AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "UBERON:0000010") "The process whose specific outcome is the progression of the peripheral nervous system over time, from its formation to the mature structure. The peripheral nervous system is one of the two major divisions of the nervous system. Nerves in the PNS connect the central nervous system (CNS) with sensory organs, other organs, muscles, blood vessels and glands.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0007422") +AnnotationAssertion(rdfs:label "peripheral nervous system development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (sensory organ development) + +AnnotationAssertion(Annotation( "GOC:go_curators") "The process whose specific outcome is the progression of sensory organs over time, from its formation to the mature structure.") +AnnotationAssertion(Annotation( "GOC:dph") "sense organ development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0007423") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "sensory organ development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (open tracheal system development) + +AnnotationAssertion(Annotation( "GOC:mtg_sensu") Annotation( "PMID:8625828") "The process whose specific outcome is the progression of an open tracheal system over time, from its formation to the mature structure. An open tracheal system is a respiratory system, a branched network of epithelial tubes that supplies oxygen to target tissues via spiracles. An example of this is found in Drosophila melanogaster.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0007424") +AnnotationAssertion(rdfs:comment "See also the fly_anatomy.ontology term 'tracheal system ; FBbt:00005024'.") +AnnotationAssertion(rdfs:label "open tracheal system development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectAllValuesFrom( )) + +# Class: (salivary gland development) + +AnnotationAssertion(Annotation( "GOC:jid") Annotation( "UBERON:0001044") "The process whose specific outcome is the progression of the salivary gland over time, from its formation to the mature structure. Salivary glands include any of the saliva-secreting exocrine glands of the oral cavity.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0007431") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "salivary gland development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (salivary gland morphogenesis) + +AnnotationAssertion(Annotation( "GOC:jid") "The process in which the anatomical structures of the salivary gland are generated and organized.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0007435") +AnnotationAssertion(rdfs:label "salivary gland morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (ectodermal digestive tract development) + +AnnotationAssertion(Annotation( "GOC:curators") "The process whose specific outcome is the progression of the ectodermal digestive tract over time, from its formation to the mature structure. The ectodermal digestive tract includes those portions that are derived from ectoderm.") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") "ectodermal gut development") +AnnotationAssertion( "GO:0007439") +AnnotationAssertion(rdfs:label "ectodermal digestive tract development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (foregut morphogenesis) + +AnnotationAssertion(Annotation( "GOC:jid") "The process in which the anatomical structures of the foregut are generated and organized.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0007440") +AnnotationAssertion(rdfs:label "foregut morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (hindgut morphogenesis) + +AnnotationAssertion(Annotation( "GOC:jid") "The process in which the anatomical structures of the hindgut are generated and organized.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0007442") +AnnotationAssertion(rdfs:label "hindgut morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (Malpighian tubule morphogenesis) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "ISBN:0582227089") "The process in which the anatomical structures of the Malpighian tubule are generated and organized. This process takes place entirely during the embryonic phase. A Malpighian tubule is a fine, thin-walled excretory tubule in insects which leads into the posterior part of the gut.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0007443") +AnnotationAssertion(rdfs:comment "See also the fly_anatomy.ontology term 'Malpighian tubule ; FBbt:00005786'.") +AnnotationAssertion(rdfs:label "Malpighian tubule morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (imaginal disc development) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "ISBN:0879694238") "The process whose specific outcome is the progression of the imaginal disc over time, from its formation to the metamorphosis to form adult structures. Imaginal discs are epithelial infoldings in the larvae of holometabolous insects that develop into adult structures (legs, antennae, wings, etc.).") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0007444") +AnnotationAssertion(rdfs:label "imaginal disc development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectAllValuesFrom( )) + +# Class: (imaginal disc growth) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:jid") Annotation( "PMID:10679387") "The increase in mass of imaginal discs by cell proliferation prior to metamorphosis. Imaginal discs are epithelial infoldings in the larvae of holometabolous insects that develop into adult structures (legs, antennae, wings, etc.) during metamorphosis from larval to adult form.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0007446") +AnnotationAssertion(rdfs:label "imaginal disc growth") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (eye-antennal disc morphogenesis) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "ISBN:0879694238") "The process in which the anatomical structures derived from the eye-antennal disc are generated and organized. This includes the transformation of an eye-antennal imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into recognizable adult structures including the eye, antenna, head capsule and maxillary palps.") +AnnotationAssertion( "eye-antennal disc metamorphosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0007455") +AnnotationAssertion(rdfs:label "eye-antennal disc morphogenesis") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (antennal development) + +AnnotationAssertion(Annotation( "http://fly.ebi.ac.uk/.bin/cvreport2?id=FBcv0004526") "The process whose specific outcome is the progression of the antenna over time, from its formation to the mature structure. The antenna are the sensory structures on the head that are capable of detecting various environmental stimuli.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0007469") +AnnotationAssertion(rdfs:label "antennal development") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (wing disc morphogenesis) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "ISBN:0879694238") "The process in which the anatomical structures derived from the wing disc are generated and organized. This includes the transformation of a wing imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into recognizable adult structures including the wing hinge, wing blade and pleura.") +AnnotationAssertion( "wing disc metamorphosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0007472") +AnnotationAssertion(rdfs:label "wing disc morphogenesis") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (imaginal disc-derived wing morphogenesis) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:mtg_sensu") "The process in which the anatomical structures of the imaginal disc-derived wing are generated and organized. The wing is an appendage modified for flying.") +AnnotationAssertion( "wing morphogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0007476") +AnnotationAssertion(rdfs:label "imaginal disc-derived wing morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (leg disc morphogenesis) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "ISBN:0879694238") "The process in which the anatomical structures derived from the leg disc are generated and organized. This includes the transformation of a leg imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into recognizable adult structures including the leg, coxa and ventral thoracic pleura.") +AnnotationAssertion( "leg disc metamorphosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0007478") +AnnotationAssertion(rdfs:label "leg disc morphogenesis") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (imaginal disc-derived leg morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_sensu") Annotation( "ISBN:0879694238") "The process in which the anatomical structures of a leg derived from an imaginal disc are generated and organized. A leg is a limb on which an animal walks and stands. An example of this is found in Drosophila melanogaster.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0007480") +AnnotationAssertion(rdfs:label "imaginal disc-derived leg morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectAllValuesFrom( )) + +# Class: (haltere disc morphogenesis) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "ISBN:0879694238") "The process in which the anatomical structures derived from the haltere disc are generated and organized. This includes the transformation of a haltere imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into the recognizable adult capitellum, pedicel, haltere sclerite, metathoracic spiracle and metanotum.") +AnnotationAssertion( "haltere disc metamorphosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0007481") +AnnotationAssertion(rdfs:label "haltere disc morphogenesis") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (haltere development) + +AnnotationAssertion(Annotation( "GOC:jid") Annotation( "http://www.earthlife.net") "The process whose specific outcome is the progression of the haltere over time, from its formation to the mature structure. The haltere is the club-shaped 'balancers' found on each side of the metathorax among the true flies (Diptera). They are the much-modified hind wings.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0007482") +AnnotationAssertion(rdfs:label "haltere development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (endoderm development) AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "The process whose specific outcome is the progression of the endoderm over time, from its formation to the mature structure. The endoderm is the innermost germ layer that develops into the gastrointestinal tract, the lungs and associated tissues.") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0007492") AnnotationAssertion(rdfs:label "endoderm development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (midgut development) + +AnnotationAssertion(Annotation( "GOC:jid") Annotation( "UBERON:0001045") "The process whose specific outcome is the progression of the midgut over time, from its formation to the mature structure. The midgut is the middle part of the alimentary canal from the stomach, or entrance of the bile duct, to, or including, the large intestine.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0007494") +AnnotationAssertion(rdfs:label "midgut development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + # Class: (mesoderm development) AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "The process whose specific outcome is the progression of the mesoderm over time, from its formation to the mature structure. The mesoderm is the middle germ layer that develops into muscle, bone, cartilage, blood and connective tissue.") @@ -31022,8 +58216,101 @@ AnnotationAssertion( "GO:0007498") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "mesoderm development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (fat body development) + +AnnotationAssertion(Annotation( "ISBN:0582227089") "The process whose specific outcome is the progression of the fat body over time, from its formation to the mature structure. A fat body is an insect gland dorsal to the insect gut, with a function analogous to that of the vertebrate liver. It is a storage organ for fats, glycogen and protein and is a major site of intermediary metabolism.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0007503") +AnnotationAssertion(rdfs:label "fat body development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectAllValuesFrom( )) + +# Class: (gonadal mesoderm development) + +AnnotationAssertion(Annotation( "GOC:ai") "The process whose specific outcome is the progression of the gonadal mesoderm over time, from its formation to the mature structure. The gonadal mesoderm is the middle layer of the three primary germ layers of the embryo which will go on to form the gonads of the organism.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0007506") +AnnotationAssertion(rdfs:label "gonadal mesoderm development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (heart development) + +AnnotationAssertion(Annotation( "GOC:jid") Annotation( "UBERON:0000948") "The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.") +AnnotationAssertion( "GO:0007511") +AnnotationAssertion( "Wikipedia:Heart_development") +AnnotationAssertion( "dorsal vessel development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "cardiac development") +AnnotationAssertion( "GO:0007507") +AnnotationAssertion(rdfs:label "heart development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (hemocyte development) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:mtg_sensu") "The process whose specific outcome is the progression of the hemocyte over time, from its formation to the mature structure. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen.") +AnnotationAssertion( "arthropod blood cell development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0007516") +AnnotationAssertion(rdfs:label "hemocyte development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectAllValuesFrom( )) + +# Class: (muscle organ development) + +AnnotationAssertion(Annotation( "GOC:jid") Annotation( "ISBN:0198506732") "The process whose specific outcome is the progression of the muscle over time, from its formation to the mature structure. The muscle is an organ consisting of a tissue made up of various elongated cells that are specialized to contract and thus to produce movement and mechanical work.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0007517") +AnnotationAssertion(rdfs:label "muscle organ development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (skeletal muscle tissue development) + +AnnotationAssertion(Annotation( "GOC:mtg_muscle") "The developmental sequence of events leading to the formation of adult skeletal muscle tissue. The main events are: the fusion of myoblasts to form myotubes that increase in size by further fusion to them of myoblasts, the formation of myofibrils within their cytoplasm and the establishment of functional neuromuscular junctions with motor neurons. At this stage they can be regarded as mature muscle fibers.") +AnnotationAssertion( "GO:0048637") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "myogenesis") +AnnotationAssertion( "GO:0007519") +AnnotationAssertion(rdfs:label "skeletal muscle tissue development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (somatic muscle development) + +AnnotationAssertion(Annotation( "GOC:jid") Annotation( "GOC:mtg_muscle") "The process whose specific outcome is the progression of the somatic muscle over time, from its formation to the mature structure. Somatic muscles are striated muscle structures that connect to the exoskeleton or cuticle.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0007525") +AnnotationAssertion(rdfs:label "somatic muscle development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (neuromuscular junction development) + +AnnotationAssertion(Annotation( "GOC:mtg_OBO2OWL_2013") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a neuromuscular junction.") +AnnotationAssertion( "neuromuscular junction organization") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:pr") "NMJ stability") +AnnotationAssertion(Annotation( "GOC:pr") "neuromuscular junction stability") +AnnotationAssertion( "GO:0007528") +AnnotationAssertion(rdfs:label "neuromuscular junction development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (sex differentiation) AnnotationAssertion(Annotation( "GOC:ai") "The establishment of the sex of an organism by physical differentiation.") @@ -31087,7 +58374,7 @@ AnnotationAssertion( "GO:0007560") AnnotationAssertion(rdfs:label "imaginal disc morphogenesis") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) +SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) @@ -31102,6 +58389,15 @@ AnnotationAssertion(rdfs:label "eclo SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (regulation of eclosion) + +AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198600461") "Any process that modulates the frequency, rate or extent of the emergence of an insect from a pupa-case or of a larva from an egg.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0007563") +AnnotationAssertion(rdfs:label "regulation of eclosion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + # Class: (female pregnancy) AnnotationAssertion(Annotation( "ISBN:0192800825") "The set of physiological processes that allow an embryo or foetus to develop within the body of a female animal. It covers the time from fertilization of a female ovum by a male spermatozoon until birth.") @@ -31117,6 +58413,17 @@ SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectAllValuesFrom( )) +# Class: (embryo implantation) + +AnnotationAssertion(Annotation( "GOC:isa_complete") Annotation( "http://www.medterms.com") "Attachment of the blastocyst to the uterine lining.") +AnnotationAssertion( "blastocyst implantation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0007566") +AnnotationAssertion(rdfs:label "embryo implantation") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (respiratory gaseous exchange by respiratory system) AnnotationAssertion(Annotation( "ISBN:0198506732") "The process of gaseous exchange between an organism and its environment. In plants, microorganisms, and many small animals, air or water makes direct contact with the organism's cells or tissue fluids, and the processes of diffusion supply the organism with dioxygen (O2) and remove carbon dioxide (CO2). In larger animals the efficiency of gaseous exchange is improved by specialized respiratory organs, such as lungs and gills, which are ventilated by breathing mechanisms.") @@ -31193,6 +58500,7 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0007596") AnnotationAssertion(rdfs:label "blood coagulation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) @@ -31334,6 +58642,32 @@ AnnotationAssertion( "copulation") SubClassOf( ) +# Class: (rhythmic behavior) + +AnnotationAssertion(Annotation( "GOC:jl") Annotation( "GOC:pr") "The specific behavior of an organism that recur with measured regularity.") +AnnotationAssertion( "rhythmic behavioral response to stimulus") +AnnotationAssertion( "rhythmic behaviour") +AnnotationAssertion( "rhythmic behavioural response to stimulus") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0007622") +AnnotationAssertion(rdfs:label "rhythmic behavior") +SubClassOf( ) + +# Class: (circadian rhythm) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:go_curators") "Any biological process in an organism that recurs with a regularity of approximately 24 hours.") +AnnotationAssertion( "GO:0050895") +AnnotationAssertion( "Wikipedia:Circadian_rhythm") +AnnotationAssertion( "circadian process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "circadian response") +AnnotationAssertion( "response to circadian rhythm") +AnnotationAssertion( "GO:0007623") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "circadian rhythm") +SubClassOf( ) + # Class: (grooming behavior) AnnotationAssertion(Annotation( "GOC:jl") Annotation( "GOC:pr") "The specific behavior of an organism relating to grooming, cleaning and brushing to remove dirt and parasites.") @@ -31423,8 +58757,128 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0008016") AnnotationAssertion(rdfs:label "regulation of heart contraction") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (microtubule binding) + +AnnotationAssertion(Annotation( "GOC:krc") "Binding to a microtubule, a filament composed of tubulin monomers.") +AnnotationAssertion(Annotation(rdfs:label "Viral UL47:UL48 Proteins Bind HCMV Tegumented Virion to Host Microtuble and Dynein complexs") "Reactome:R-HSA-9614343") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "microtubule severing activity") +AnnotationAssertion( "microtubule/chromatin interaction") +AnnotationAssertion( "GO:0008017") +AnnotationAssertion(rdfs:label "microtubule binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (monocarboxylic acid transmembrane transporter activity) + +AnnotationAssertion(Annotation( "GOC:ai") "Enables the transfer of monocarboxylic acids from one side of a membrane to the other. A monocarboxylic acid is an organic acid with one COOH group.") +AnnotationAssertion( "GO:0008505") +AnnotationAssertion(Annotation(rdfs:label "SLC5A8 transports monocarboxylates from extracellular region to cytosol") "Reactome:R-HSA-429749") +AnnotationAssertion(Annotation(rdfs:label "SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol") "Reactome:R-HSA-433698") +AnnotationAssertion(Annotation(rdfs:label "Defective SLC16A1 does not cotransport monocarboxylates, H+ from extracellular region to cytosol") "Reactome:R-HSA-5624211") +AnnotationAssertion(Annotation(rdfs:label "SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol") "Reactome:R-HSA-9645220") +AnnotationAssertion( "monocarboxylate carrier") +AnnotationAssertion( "prostaglandin/thromboxane transporter activity") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0008028") +AnnotationAssertion(rdfs:label "monocarboxylic acid transmembrane transporter activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (ocellus development) + +AnnotationAssertion(Annotation( "http://fly.ebi.ac.uk/.bin/cvreport2?id=FBcv0004540") "The process whose specific outcome is the progression of the ocellus over time, from its formation to the mature structure. The ocellus is a simple visual organ of insects.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0008056") +AnnotationAssertion(rdfs:label "ocellus development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (chitin binding) + +AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0198506732") "Binding to chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues.") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0008061") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "chitin binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (glutamate receptor activity) + +AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:signaling") "Combining with glutamate and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0008066") +AnnotationAssertion(rdfs:label "glutamate receptor activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (mesodermal cell migration) + +AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:mah") Annotation( "GOC:sat") Annotation( "GOC:tb") Annotation( "PMID:25119047") "The orderly movement of mesodermal cells from one site to another.") +AnnotationAssertion( "mesoderm cell migration") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0008078") +AnnotationAssertion(rdfs:label "mesodermal cell migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (axo-dendritic transport) + +AnnotationAssertion(Annotation( "ISBN:0815316194") "The directed movement of organelles or molecules along microtubules in neuron projections.") +AnnotationAssertion( "Wikipedia:Axoplasmic_transport") +AnnotationAssertion( "axon cargo transport") +AnnotationAssertion( "axonal transport") +AnnotationAssertion( "axoplasmic transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0008088") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "axo-dendritic transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (anterograde axonal transport) + +AnnotationAssertion(Annotation( "ISBN:0815316194") "The directed movement of organelles or molecules along microtubules from the cell body toward the cell periphery in nerve cell axons.") +AnnotationAssertion( "anterograde axon cargo transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0008089") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "anterograde axonal transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (retrograde axonal transport) + +AnnotationAssertion(Annotation( "ISBN:0815316194") "The directed movement of organelles or molecules along microtubules from the cell periphery toward the cell body in nerve cell axons.") +AnnotationAssertion( "retrograde axon cargo transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0008090") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "retrograde axonal transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (cytoskeletal protein binding) + +AnnotationAssertion(Annotation( "GOC:mah") "Binding to a protein component of a cytoskeleton (actin, microtubule, or intermediate filament cytoskeleton).") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0008092") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "cytoskeletal protein binding") +SubClassOf( ) + # Class: (protein localization) AnnotationAssertion(Annotation( "GOC:ai") "Any process in which a protein is transported to, or maintained in, a specific location.") @@ -31444,9 +58898,28 @@ AnnotationAssertion( "GO:0008104") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "protein localization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) +# Class: (transcription factor binding) + +AnnotationAssertion(Annotation( "ISBN:0198506732") "Binding to a transcription factor, a protein required to initiate or regulate transcription.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/19354"^^xsd:anyURI) +AnnotationAssertion( "TF binding") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "transcription regulator binding") +AnnotationAssertion( "GO:0008134") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:comment "Note that this term should not be used for direct annotation. Please consier one of the more specific descendants, GO:0140297 ; DNA-binding transcription factor binding, GO:0140296 ; general transcription initiation factor binding or GO:0001221 ; transcription coregulator binding.") +AnnotationAssertion(rdfs:label "transcription factor binding") +SubClassOf( ) + # Class: (biological_process) AnnotationAssertion(Annotation( "GOC:pdt") "A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence.") @@ -31500,6 +58973,21 @@ SubClassOf( ) DisjointClasses( ) +# Class: (neuropeptide receptor activity) + +AnnotationAssertion(Annotation( "GOC:ai") "Combining with a neuropeptide to initiate a change in cell activity.") +AnnotationAssertion( ) +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0008188") +AnnotationAssertion(rdfs:label "neuropeptide receptor activity") +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses( ObjectSomeValuesFrom( )) + # Class: (steroid metabolic process) AnnotationAssertion(Annotation( "ISBN:0198547684") "The chemical reactions and pathways involving steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.") @@ -31508,6 +58996,7 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0008202") AnnotationAssertion(rdfs:label "steroid metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) @@ -31518,6 +59007,7 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0008206") AnnotationAssertion(rdfs:label "bile acid metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ) @@ -31529,10 +59019,35 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0008207") AnnotationAssertion(rdfs:label "C21-steroid hormone metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ) +# Class: (C21-steroid hormone catabolic process) + +AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways resulting in the breakdown of C21-steroid hormones, steroid compounds containing 21 carbons which function as hormones.") +AnnotationAssertion( "C21-steroid hormone breakdown") +AnnotationAssertion( "C21-steroid hormone catabolism") +AnnotationAssertion( "C21-steroid hormone degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0008208") +AnnotationAssertion(rdfs:label "C21-steroid hormone catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (glucocorticoid metabolic process) + +AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving glucocorticoids, hormonal C21 corticosteroids synthesized from cholesterol. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects.") +AnnotationAssertion( "glucocorticoid metabolism") +AnnotationAssertion( "glucocorticosteroid metabolic process") +AnnotationAssertion( "glucocorticosteroid metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0008211") +AnnotationAssertion(rdfs:label "glucocorticoid metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + # Class: (mineralocorticoid metabolic process) AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving mineralocorticoids, hormonal C21 corticosteroids synthesized from cholesterol. Mineralocorticoids act primarily on water and electrolyte balance.") @@ -31540,6 +59055,7 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0008212") AnnotationAssertion(rdfs:label "mineralocorticoid metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ) @@ -31557,6 +59073,55 @@ AnnotationAssertion(rdfs:label "regu SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (cell death) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:mtg_apoptosis") Annotation( "PMID:25236395") "Any biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as apoptotic bodies). The cell corpse (or its fragments) may be engulfed by an adjacent cell in vivo, but engulfment of whole cells should not be considered a strict criteria to define cell death as, under some circumstances, live engulfed cells can be released from phagosomes (see PMID:18045538).") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/24680"^^xsd:anyURI) +AnnotationAssertion( "biological_process") +AnnotationAssertion( "accidental cell death") +AnnotationAssertion( "necrosis") +AnnotationAssertion( "GO:0008219") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:comment "This term should not be used for direct annotation, it is currently kept in GO as a placeholder for describing cell death phenotypes in uPHENO. When information is provided on a programmed cell death mechanism, annotations should be made to the appropriate descendant of 'cell death' (such as, but not limited to, GO:0097300 'programmed necrotic cell death' or GO:0006915 'apoptotic process'). Unintentional cell death, i.e. cell death caused by injury, ageing, or cell phenotypes observed as a result of a pathological mutation in an essential gene should NOT be annotated using GO terms.") +AnnotationAssertion(rdfs:label "cell death") +SubClassOf( ) + +# Class: (G protein-coupled amine receptor activity) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:dph") "Combining with an extracellular amine and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.") +AnnotationAssertion( "G-protein coupled amine receptor activity") +AnnotationAssertion(Annotation( "GOC:bf") "amine receptor activity, G-protein coupled") +AnnotationAssertion( "biogenic amine receptor") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0008227") +AnnotationAssertion(rdfs:label "G protein-coupled amine receptor activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (sulfate transport) + +AnnotationAssertion(Annotation( "GOC:krc") "The directed movement of sulfate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion( "GO:0006870") +AnnotationAssertion( "sulphate transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0008272") +AnnotationAssertion(rdfs:label "sulfate transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of G protein-coupled receptor signaling pathway) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of G protein-coupled receptor signaling pathway.") +AnnotationAssertion( "regulation of G protein coupled receptor protein signaling pathway") +AnnotationAssertion( "regulation of G protein coupled receptor protein signalling pathway") +AnnotationAssertion( "regulation of G-protein coupled receptor protein signaling pathway") +AnnotationAssertion( "regulation of G-protein coupled receptor protein signalling pathway") +AnnotationAssertion( "regulation of G-protein-coupled receptor protein signalling pathway") +AnnotationAssertion( "regulation of GPCR protein signaling pathway") +AnnotationAssertion( "regulation of GPCR protein signalling pathway") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0008277") +AnnotationAssertion(rdfs:label "regulation of G protein-coupled receptor signaling pathway") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (cell population proliferation) AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:mb") "The multiplication or reproduction of cells, resulting in the expansion of a cell population.") @@ -31656,7 +59221,6 @@ AnnotationAssertion( "GO:0008291") AnnotationAssertion(rdfs:label "acetylcholine metabolic process") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) # Class: (acetylcholine biosynthetic process) @@ -31669,7 +59233,6 @@ AnnotationAssertion( "GO:0008292") AnnotationAssertion(rdfs:label "acetylcholine biosynthetic process") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) # Class: (isoprenoid biosynthetic process) @@ -31725,6 +59288,91 @@ AnnotationAssertion( "associative learning") SubClassOf( ) +# Class: (protein transmembrane transporter activity) + +AnnotationAssertion(Annotation( "GOC:jl") "Enables the transfer of a protein from one side of a membrane to the other.") +AnnotationAssertion( "GO:0015266") +AnnotationAssertion( "GO:0015463") +AnnotationAssertion(Annotation(rdfs:label "TOMM40 complex translocates proteins from the cytosol to the mitochondrial intermembrane space") "Reactome:R-HSA-1268022") +AnnotationAssertion(Annotation(rdfs:label "TIMM23 PAM translocates proteins from the mitochondrial intermembrane space to the mitochondrial matrix") "Reactome:R-HSA-1299475") +AnnotationAssertion(Annotation(rdfs:label "Monoubiquitinated N-myristoyl GAG polyprotein is targeted to the late endosomal vesicle membrane by the ESCRT-I complex") "Reactome:R-HSA-184269") +AnnotationAssertion(Annotation(rdfs:label "Transport of GAG to the Plasma Membrane") "Reactome:R-HSA-3149434") +AnnotationAssertion(Annotation(rdfs:label "Pink1 is recruited from the cytoplasm to the mitochondria") "Reactome:R-HSA-5205661") +AnnotationAssertion(Annotation(rdfs:label "pagA(197-794):ANTRX2 oligomer transports cya and lef (target cell endosome to cytosol)") "Reactome:R-HSA-5210943") +AnnotationAssertion(Annotation(rdfs:label "pagA(197-794):ANTRX1 oligomer transports cya and lef (target cell endosome to cytosol)") "Reactome:R-HSA-5210947") +AnnotationAssertion(Annotation(rdfs:label "tetX HC transports tetX LC from target cell endosome membrane into cytosol") "Reactome:R-HSA-5228406") +AnnotationAssertion(Annotation(rdfs:label "AP4 transports APP from trans-Golgi network to endosome lumen") "Reactome:R-HSA-5229111") +AnnotationAssertion(Annotation(rdfs:label "botB HC transports botB LC from target cell synaptic vesicle membrane into cytosol") "Reactome:R-HSA-5244404") +AnnotationAssertion(Annotation(rdfs:label "botA HC transports botA LC from target cell synaptic vesicle membrane into cytosol") "Reactome:R-HSA-5244428") +AnnotationAssertion(Annotation(rdfs:label "botE HC transports botE LC from target cell synaptic vesicle membrane into cytosol") "Reactome:R-HSA-5244506") +AnnotationAssertion(Annotation(rdfs:label "botC HC transports botC LC from target cell synaptic vesicle membrane to cytosol") "Reactome:R-HSA-5246514") +AnnotationAssertion(Annotation(rdfs:label "botD HC transports botD LC from target cell synaptic vesicle membrane into cytosol") "Reactome:R-HSA-5250616") +AnnotationAssertion(Annotation(rdfs:label "botF HC transports botF LC from target cell synaptic vesicle membrane into cytosol") "Reactome:R-HSA-5250884") +AnnotationAssertion(Annotation(rdfs:label "botG HC transports botG LC from target cell synaptic vesicle membrane into cytosol") "Reactome:R-HSA-5250972") +AnnotationAssertion(Annotation(rdfs:label "DT fragment B transports DT fragment A from target cell endosome membrane") "Reactome:R-HSA-5336420") +AnnotationAssertion(Annotation(rdfs:label "SecA2 transports SapM from cytoplasm to cytosol") "Reactome:R-HSA-9636375") +AnnotationAssertion(Annotation(rdfs:label "HCMV C Nucleocapsid Translocation") "Reactome:R-HSA-9698930") +AnnotationAssertion(Annotation(rdfs:label "HCMV B Nucleocapsid Translocation") "Reactome:R-HSA-9698933") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "protein channel activity") +AnnotationAssertion( "GO:0008320") +AnnotationAssertion(rdfs:label "protein transmembrane transporter activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "GO_REF:0000090") ObjectSomeValuesFrom( )) + +# Class: (monoatomic cation transmembrane transporter activity) + +AnnotationAssertion(Annotation( "GOC:dgf") Annotation( "GOC:mtg_transport") Annotation( "ISBN:0815340729") "Enables the transfer of cation from one side of a membrane to the other.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/24479"^^xsd:anyURI) +AnnotationAssertion( "cation transmembrane transporter activity") +AnnotationAssertion( "transmembrane cation transporter activity") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0008324") +AnnotationAssertion(rdfs:label "monoatomic cation transmembrane transporter activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (glial cell migration) + +AnnotationAssertion(Annotation( "GOC:jl") Annotation( "GOC:mtg_sensu") "The orderly movement of a glial cell, non-neuronal cells that provide support and nutrition, maintain homeostasis, form myelin, and participate in signal transmission in the nervous system.") +AnnotationAssertion( "GO:0043359") +AnnotationAssertion( "glia cell migration") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0008347") +AnnotationAssertion(rdfs:label "glial cell migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectAllValuesFrom( )) + +# Class: (negative regulation of antimicrobial humoral response) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate, or extent of an antimicrobial humoral response.") +AnnotationAssertion( "GO:0042154") +AnnotationAssertion( "GO:0042155") +AnnotationAssertion( "attenuation of antimicrobial humoral response") +AnnotationAssertion( "down regulation of antimicrobial humoral response") +AnnotationAssertion( "down-regulation of antimicrobial humoral response") +AnnotationAssertion( "downregulation of antimicrobial humoral response") +AnnotationAssertion( "inhibition of antimicrobial humoral response") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0008348") +AnnotationAssertion(rdfs:label "negative regulation of antimicrobial humoral response") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (germ cell migration) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:jl") "The orderly movement of a cell specialized to produce haploid gametes through the embryo from its site of production to the place where the gonads will form.") +AnnotationAssertion( "germ-cell migration") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "primordial germ cell migration") +AnnotationAssertion( "GO:0008354") +AnnotationAssertion(rdfs:label "germ cell migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (olfactory learning) AnnotationAssertion(Annotation( "ISBN:0582227089") "Any process in an organism in which a relatively long-lasting adaptive behavioral change occurs in response to (repeated) exposure to an olfactory cue.") @@ -31734,6 +59382,39 @@ AnnotationAssertion(rdfs:label "olfa SubClassOf( ) SubClassOf( ) +# Class: (asymmetric cell division) + +AnnotationAssertion(Annotation( "PMID:11672519") "The asymmetric division of cells to produce two daughter cells with different developmental potentials. It is of fundamental significance for the generation of cell diversity.") +AnnotationAssertion( "Wikipedia:Asymmetric_cell_division") +AnnotationAssertion( "asymmetrical cell division") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "asymmetric cytokinesis") +AnnotationAssertion( "asymmetrical cytokinesis") +AnnotationAssertion( "GO:0008356") +AnnotationAssertion(rdfs:label "asymmetric cell division") +SubClassOf( ) + +# Class: (maternal determination of anterior/posterior axis, embryo) + +AnnotationAssertion(Annotation( "ISBN:0879694238") Annotation( "http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm") "The specification of the anterior/posterior axis of the embryo by gradients of maternally-transcribed gene products; exemplified in insects by the morphogens, bicoid and nanos.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0008358") +AnnotationAssertion(rdfs:label "maternal determination of anterior/posterior axis, embryo") +SubClassOf( ) + +# Class: (axon ensheathment) + +AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0878932437") "Any process in which the axon of a neuron is insulated, and that insulation maintained, thereby preventing dispersion of the electrical signal.") +AnnotationAssertion( "GO:0042553") +AnnotationAssertion( "cellular axon ensheathment") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "cellular nerve ensheathment") +AnnotationAssertion( "nerve ensheathment") +AnnotationAssertion( "GO:0008366") +AnnotationAssertion(rdfs:label "axon ensheathment") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (gonad development) AnnotationAssertion(Annotation( "GOC:ems") Annotation( "ISBN:0198506732") "The process whose specific outcome is the progression of the gonad over time, from its formation to the mature structure. The gonad is an animal organ that produces gametes; in some species it also produces hormones.") @@ -31741,12 +59422,65 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:0008406") AnnotationAssertion(rdfs:label "gonad development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (melatonin receptor activity) + +AnnotationAssertion(Annotation( "GOC:ai") Annotation( "ISBN:0198506732") "Combining with melatonin, N-acetyl-5-methoxytryptamine, to initiate a change in cell activity. Melatonin is a neuroendocrine substance that stimulates the aggregation of melanosomes in melanophores, thus lightening the skin.") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0008502") +AnnotationAssertion(rdfs:label "melatonin receptor activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (monoamine transmembrane transporter activity) + +AnnotationAssertion(Annotation( "GOC:mah") "Enables the transfer of monoamines, organic compounds that contain one amino group that is connected to an aromatic ring by an ethylene group (-CH2-CH2-), from one side of a membrane to the other.") +AnnotationAssertion( "GO:0015201") +AnnotationAssertion(Annotation(rdfs:label "Loading of dopamine into synaptic veiscles") "Reactome:R-HSA-372542") +AnnotationAssertion(Annotation(rdfs:label "SLC6A3 cotransports DA, Na+ from extracellular region to cytosol") "Reactome:R-HSA-379393") +AnnotationAssertion(Annotation(rdfs:label "loading of Serotonin in synaptic vesicles") "Reactome:R-HSA-380586") +AnnotationAssertion(Annotation(rdfs:label "Reuptake of serotonin from the synapse") "Reactome:R-HSA-380620") +AnnotationAssertion(Annotation(rdfs:label "VMAT1/2 can mediate the transport of biogenic amines") "Reactome:R-HSA-444160") +AnnotationAssertion(Annotation(rdfs:label "Defective SLC6A3 does not cotransport DA, Na+ from extracellular region to cytosol") "Reactome:R-HSA-5660706") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0008504") +AnnotationAssertion(rdfs:label "monoamine transmembrane transporter activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (organic anion transmembrane transporter activity) + +AnnotationAssertion(Annotation( "GOC:ai") "Enables the transfer of organic anions from one side of a membrane to the other. Organic anions are atoms or small molecules with a negative charge which contain carbon in covalent linkage.") +AnnotationAssertion(Annotation(rdfs:label "Growing HA is extruded from the cell by ABCC5") "Reactome:R-HSA-2142859") +AnnotationAssertion(Annotation(rdfs:label "OAT1-3 transport organic anions with antiport of dicarboxylic acids") "Reactome:R-HSA-561041") +AnnotationAssertion(Annotation(rdfs:label "SLC22A8 transports Cipro into renal cell") "Reactome:R-HSA-9794830") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0008514") +AnnotationAssertion(rdfs:label "organic anion transmembrane transporter activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (G protein-coupled peptide receptor activity) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Combining with a peptide and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.") +AnnotationAssertion( "G protein coupled peptide receptor activity") +AnnotationAssertion( "G-protein coupled peptide receptor activity") +AnnotationAssertion( "peptide receptor activity, G protein coupled") +AnnotationAssertion(Annotation( "GOC:bf") "peptide receptor activity, G-protein coupled") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0008528") +AnnotationAssertion(rdfs:label "G protein-coupled peptide receptor activity") +SubClassOf( ) +SubClassOf( ) + # Class: (epidermis development) AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "UBERON:0001003") "The process whose specific outcome is the progression of the epidermis over time, from its formation to the mature structure. The epidermis is the outer epithelial layer of an animal, it may be a single layer that produces an extracellular material (e.g. the cuticle of arthropods) or a complex stratified squamous epithelium, as in the case of many vertebrate species.") @@ -31760,6 +59494,18 @@ SubClassOf( ObjectComplementOf(Object SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) DisjointClasses( ObjectSomeValuesFrom( )) +# Class: (male gonad development) + +AnnotationAssertion(Annotation( "GOC:jid") "The process whose specific outcome is the progression of the male gonad over time, from its formation to the mature structure.") +AnnotationAssertion(Annotation( "GOC:sl") "testicular development") +AnnotationAssertion(Annotation( "GOC:sl") "testis development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0008584") +AnnotationAssertion(rdfs:label "male gonad development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (female gonad development) AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GOC:tb") "The process whose specific outcome is the progression of the female gonad over time, from its formation to the mature structure.") @@ -31770,12 +59516,47 @@ AnnotationAssertion(Annotation( "GOC:sl") "ovary development") AnnotationAssertion( "GO:0008585") AnnotationAssertion(rdfs:label "female gonad development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) DisjointClasses( ObjectSomeValuesFrom( )) +# Class: (imaginal disc-derived wing vein morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_sensu") "The process in which anatomical structures of the veins on an imaginal disc-derived wing are generated and organized.") +AnnotationAssertion( "wing vein morphogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0008586") +AnnotationAssertion(rdfs:label "imaginal disc-derived wing vein morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (photoreceptor cell morphogenesis) + +AnnotationAssertion(Annotation( "GOC:jid") Annotation( "GOC:mah") "The process in which the structures of a photoreceptor cell are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a photoreceptor cell, a sensory cell that reacts to the presence of light. An example of this is found in Drosophila melanogaster.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "photoreceptor development") +AnnotationAssertion( "GO:0008594") +AnnotationAssertion(rdfs:label "photoreceptor cell morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (anterior/posterior axis specification, embryo) + +AnnotationAssertion(Annotation( "ISBN:0879694238") Annotation( "http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm") "The specification of the anterior/posterior axis of the embryo by the products of genes expressed maternally and genes expressed in the zygote.") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") "anterior/posterior axis determination, embryo") +AnnotationAssertion( "GO:0008595") +AnnotationAssertion(rdfs:label "anterior/posterior axis specification, embryo") +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (lipid biosynthetic process) AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways resulting in the formation of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.") @@ -31787,9 +59568,112 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:0008610") AnnotationAssertion(rdfs:label "lipid biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) +# Class: (carbohydrate transport) + +AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of carbohydrate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carbohydrates are a group of organic compounds based of the general formula Cx(H2O)y.") +AnnotationAssertion( "GO:0006861") +AnnotationAssertion( "GO:0008644") +AnnotationAssertion( "sugar transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0008643") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "carbohydrate transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (hexose transmembrane transport) + +AnnotationAssertion(Annotation( "GOC:vw") "The process in which hexose is transported across a membrane. Hexoses are aldoses with a chain of six carbon atoms in the molecule.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2010-04-08T10:27:23Z") +AnnotationAssertion( "GO:0008646") +AnnotationAssertion( "GO:0008647") +AnnotationAssertion( "GO:0035428") +AnnotationAssertion( "high-affinity hexose transport") +AnnotationAssertion( "low-affinity hexose transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "hexose membrane transport") +AnnotationAssertion( "hexose transport") +AnnotationAssertion( "GO:0008645") +AnnotationAssertion(rdfs:comment "Note that this term is not intended for use in annotating lateral movement within membranes.") +AnnotationAssertion(rdfs:label "hexose transmembrane transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (amino acid biosynthetic process) + +AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of amino acids, organic acids containing one or more amino substituents.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/17904"^^xsd:anyURI) +AnnotationAssertion( "Wikipedia:Amino_acid_synthesis") +AnnotationAssertion( "amino acid anabolism") +AnnotationAssertion( "amino acid biosynthesis") +AnnotationAssertion( "amino acid formation") +AnnotationAssertion( "amino acid synthesis") +AnnotationAssertion( "cellular amino acid biosynthetic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0008652") +AnnotationAssertion(rdfs:label "amino acid biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (phospholipid biosynthetic process) + +AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of a phospholipid, a lipid containing phosphoric acid as a mono- or diester.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/20092"^^xsd:anyURI) +AnnotationAssertion( "MetaCyc:PHOSLIPSYN-PWY") +AnnotationAssertion( "MetaCyc:PHOSLIPSYN2-PWY") +AnnotationAssertion( "phospholipid anabolism") +AnnotationAssertion( "phospholipid biosynthesis") +AnnotationAssertion( "phospholipid formation") +AnnotationAssertion( "phospholipid synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0008654") +AnnotationAssertion(rdfs:label "phospholipid biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (catabolic process) + +AnnotationAssertion(Annotation( "ISBN:0198547684") "The chemical reactions and pathways resulting in the breakdown of substances, including the breakdown of carbon compounds with the liberation of energy for use by the cell or organism.") +AnnotationAssertion( "jl") +AnnotationAssertion( "2012-10-17T15:52:35Z") +AnnotationAssertion( "GO:0044243") +AnnotationAssertion( "GO:0044712") +AnnotationAssertion( "Wikipedia:Catabolism") +AnnotationAssertion( "breakdown") +AnnotationAssertion( "catabolism") +AnnotationAssertion( "degradation") +AnnotationAssertion( "multicellular organismal catabolic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "single-organism catabolic process") +AnnotationAssertion( "GO:0009056") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "catabolic process") +SubClassOf( ) + +# Class: (macromolecule catabolic process) + +AnnotationAssertion(Annotation( "GOC:mah") "The chemical reactions and pathways resulting in the breakdown of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.") +AnnotationAssertion( "GO:0043285") +AnnotationAssertion( "GO:0044266") +AnnotationAssertion(Annotation( "GOC:mtg_chebi_dec09") "biopolymer catabolic process") +AnnotationAssertion( "macromolecule breakdown") +AnnotationAssertion( "macromolecule catabolism") +AnnotationAssertion( "macromolecule degradation") +AnnotationAssertion( "multicellular organismal macromolecule catabolic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "cellular macromolecule catabolic process") +AnnotationAssertion( "cellular macromolecule catabolism") +AnnotationAssertion( "cellular macromolecule degradation") +AnnotationAssertion( "GO:0009057") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "macromolecule catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (biosynthetic process) AnnotationAssertion(Annotation( "GOC:curators") Annotation( "ISBN:0198547684") "The chemical reactions and pathways resulting in the formation of substances; typically the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones.") @@ -31827,10 +59711,37 @@ AnnotationAssertion( "GO:0009059") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "macromolecule biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ) +# Class: (fatty acid catabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways resulting in the breakdown of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes.") +AnnotationAssertion( "Wikipedia:Fatty_acid_degradation") +AnnotationAssertion( "fatty acid breakdown") +AnnotationAssertion( "fatty acid catabolism") +AnnotationAssertion( "fatty acid degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0009062") +AnnotationAssertion(rdfs:label "fatty acid catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (amino acid catabolic process) + +AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways resulting in the breakdown of amino acids, organic acids containing one or more amino substituents.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/17904"^^xsd:anyURI) +AnnotationAssertion( "amino acid breakdown") +AnnotationAssertion( "amino acid catabolism") +AnnotationAssertion( "amino acid degradation") +AnnotationAssertion( "cellular amino acid catabolic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0009063") +AnnotationAssertion(rdfs:label "amino acid catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (glutamine family amino acid metabolic process) AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways involving amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline.") @@ -31838,8 +59749,470 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0009064") AnnotationAssertion(rdfs:label "glutamine family amino acid metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (glutamine family amino acid catabolic process) + +AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways resulting in the breakdown of amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline.") +AnnotationAssertion( "glutamine family amino acid breakdown") +AnnotationAssertion( "glutamine family amino acid catabolism") +AnnotationAssertion( "glutamine family amino acid degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0009065") +AnnotationAssertion(rdfs:label "glutamine family amino acid catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (glutamine family amino acid biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways resulting in the formation of amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline.") +AnnotationAssertion( "glutamine family amino acid anabolism") +AnnotationAssertion( "glutamine family amino acid biosynthesis") +AnnotationAssertion( "glutamine family amino acid formation") +AnnotationAssertion( "glutamine family amino acid synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0009084") +AnnotationAssertion(rdfs:label "glutamine family amino acid biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (glycoprotein metabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving glycoproteins, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide.") +AnnotationAssertion( "glycoprotein metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0009100") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "glycoprotein metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (glycoprotein biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of glycoproteins, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide.") +AnnotationAssertion( "glycoprotein anabolism") +AnnotationAssertion( "glycoprotein biosynthesis") +AnnotationAssertion( "glycoprotein formation") +AnnotationAssertion( "glycoprotein synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0009101") +AnnotationAssertion(rdfs:label "glycoprotein biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (nucleobase metabolic process) + +AnnotationAssertion(Annotation( "GOC:ma") "The chemical reactions and pathways involving a nucleobase, a nitrogenous base that is a constituent of a nucleic acid, e.g. the purines: adenine, guanine, hypoxanthine, xanthine and the pyrimidines: cytosine, uracil, thymine.") +AnnotationAssertion( "nucleobase metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0009112") +AnnotationAssertion(rdfs:label "nucleobase metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (purine nucleobase biosynthetic process) + +AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of purine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, which include adenine and guanine.") +AnnotationAssertion( "MetaCyc:PWY-841") +AnnotationAssertion( "purine base anabolism") +AnnotationAssertion( "purine base biosynthesis") +AnnotationAssertion(Annotation( "GOC:go_curators") "purine base biosynthetic process") +AnnotationAssertion( "purine base formation") +AnnotationAssertion( "purine base synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0009113") +AnnotationAssertion(rdfs:label "purine nucleobase biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (nucleoside metabolic process) + +AnnotationAssertion(Annotation( "GOC:ma") "The chemical reactions and pathways involving a nucleoside, a nucleobase linked to either beta-D-ribofuranose (a ribonucleoside) or 2-deoxy-beta-D-ribofuranose, (a deoxyribonucleoside), e.g. adenosine, guanosine, inosine, cytidine, uridine and deoxyadenosine, deoxyguanosine, deoxycytidine and thymidine (= deoxythymidine).") +AnnotationAssertion( "nucleoside metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0009116") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "nucleoside metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (nucleotide metabolic process) + +AnnotationAssertion(Annotation( "GOC:ma") "The chemical reactions and pathways involving a nucleotide, a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety; may be mono-, di- or triphosphate; this definition includes cyclic nucleotides (nucleoside cyclic phosphates).") +AnnotationAssertion( "nucleotide metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0009117") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "nucleotide metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of nucleoside metabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleosides.") +AnnotationAssertion( "regulation of nucleoside metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0009118") +AnnotationAssertion(rdfs:label "regulation of nucleoside metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (ribonucleoside metabolic process) + +AnnotationAssertion(Annotation( "GOC:jl") "The chemical reactions and pathways involving any ribonucleoside, a nucleoside in which purine or pyrimidine base is linked to a ribose (beta-D-ribofuranose) molecule.") +AnnotationAssertion( "ribonucleoside metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0009119") +AnnotationAssertion(rdfs:label "ribonucleoside metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (nucleoside diphosphate metabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving a nucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with diphosphate on the sugar.") +AnnotationAssertion( "nucleoside diphosphate metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0009132") +AnnotationAssertion(rdfs:label "nucleoside diphosphate metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (nucleoside diphosphate biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of a nucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with diphosphate on the sugar.") +AnnotationAssertion( "nucleoside diphosphate anabolism") +AnnotationAssertion( "nucleoside diphosphate biosynthesis") +AnnotationAssertion( "nucleoside diphosphate formation") +AnnotationAssertion( "nucleoside diphosphate synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0009133") +AnnotationAssertion(rdfs:label "nucleoside diphosphate biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (nucleoside diphosphate catabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of a nucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with diphosphate on the sugar.") +AnnotationAssertion( "nucleoside diphosphate breakdown") +AnnotationAssertion( "nucleoside diphosphate catabolism") +AnnotationAssertion( "nucleoside diphosphate degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0009134") +AnnotationAssertion(rdfs:label "nucleoside diphosphate catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (purine nucleoside diphosphate metabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving purine nucleoside diphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with diphosphate on the sugar.") +AnnotationAssertion( "purine nucleoside diphosphate metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0009135") +AnnotationAssertion(rdfs:label "purine nucleoside diphosphate metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (purine nucleoside diphosphate biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of purine nucleoside diphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with diphosphate on the sugar.") +AnnotationAssertion( "purine nucleoside diphosphate anabolism") +AnnotationAssertion( "purine nucleoside diphosphate biosynthesis") +AnnotationAssertion( "purine nucleoside diphosphate formation") +AnnotationAssertion( "purine nucleoside diphosphate synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0009136") +AnnotationAssertion(rdfs:label "purine nucleoside diphosphate biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (purine nucleoside diphosphate catabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of purine nucleoside diphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with diphosphate on the sugar.") +AnnotationAssertion( "purine nucleoside diphosphate breakdown") +AnnotationAssertion( "purine nucleoside diphosphate catabolism") +AnnotationAssertion( "purine nucleoside diphosphate degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0009137") +AnnotationAssertion(rdfs:label "purine nucleoside diphosphate catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (nucleoside triphosphate metabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving a nucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with triphosphate on the sugar.") +AnnotationAssertion( "nucleoside triphosphate metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0009141") +AnnotationAssertion(rdfs:label "nucleoside triphosphate metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (nucleoside triphosphate biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of a nucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with triphosphate on the sugar.") +AnnotationAssertion( "nucleoside triphosphate anabolism") +AnnotationAssertion( "nucleoside triphosphate biosynthesis") +AnnotationAssertion( "nucleoside triphosphate formation") +AnnotationAssertion( "nucleoside triphosphate synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0009142") +AnnotationAssertion(rdfs:label "nucleoside triphosphate biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (nucleoside triphosphate catabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of a nucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with triphosphate on the sugar.") +AnnotationAssertion( "nucleoside triphosphate breakdown") +AnnotationAssertion( "nucleoside triphosphate catabolism") +AnnotationAssertion( "nucleoside triphosphate degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0009143") +AnnotationAssertion(rdfs:label "nucleoside triphosphate catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (purine nucleoside triphosphate metabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving purine nucleoside triphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar.") +AnnotationAssertion( "purine nucleoside triphosphate metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0009144") +AnnotationAssertion(rdfs:label "purine nucleoside triphosphate metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (purine nucleoside triphosphate biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of purine nucleoside triphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar.") +AnnotationAssertion( "purine nucleoside triphosphate anabolism") +AnnotationAssertion( "purine nucleoside triphosphate biosynthesis") +AnnotationAssertion( "purine nucleoside triphosphate formation") +AnnotationAssertion( "purine nucleoside triphosphate synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0009145") +AnnotationAssertion(rdfs:label "purine nucleoside triphosphate biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (purine nucleoside triphosphate catabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of purine nucleoside triphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar.") +AnnotationAssertion( "purine nucleoside triphosphate breakdown") +AnnotationAssertion( "purine nucleoside triphosphate catabolism") +AnnotationAssertion( "purine nucleoside triphosphate degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0009146") +AnnotationAssertion(rdfs:label "purine nucleoside triphosphate catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (purine ribonucleotide metabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving a purine ribonucleotide, a compound consisting of ribonucleoside (a purine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.") +AnnotationAssertion( "purine ribonucleotide metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0009150") +AnnotationAssertion(rdfs:label "purine ribonucleotide metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (purine ribonucleotide biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of a purine ribonucleotide, a compound consisting of ribonucleoside (a purine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.") +AnnotationAssertion( "purine ribonucleotide anabolism") +AnnotationAssertion( "purine ribonucleotide biosynthesis") +AnnotationAssertion( "purine ribonucleotide formation") +AnnotationAssertion( "purine ribonucleotide synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0009152") +AnnotationAssertion(rdfs:label "purine ribonucleotide biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (purine ribonucleotide catabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of a purine ribonucleotide, a compound consisting of ribonucleoside (a purine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.") +AnnotationAssertion( "purine ribonucleotide breakdown") +AnnotationAssertion( "purine ribonucleotide catabolism") +AnnotationAssertion( "purine ribonucleotide degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0009154") +AnnotationAssertion(rdfs:label "purine ribonucleotide catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (nucleoside biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0140512713") "The chemical reactions and pathways resulting in the formation of any one of a family of organic molecules consisting of a purine or pyrimidine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside).") +AnnotationAssertion( "nucleoside anabolism") +AnnotationAssertion( "nucleoside biosynthesis") +AnnotationAssertion( "nucleoside formation") +AnnotationAssertion( "nucleoside synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0009163") +AnnotationAssertion(rdfs:label "nucleoside biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (nucleoside catabolic process) + +AnnotationAssertion(Annotation( "GOC:jl") "The chemical reactions and pathways resulting in the breakdown of any one of a family of organic molecules consisting of a purine or pyrimidine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside).") +AnnotationAssertion( "nucleoside breakdown") +AnnotationAssertion( "nucleoside catabolism") +AnnotationAssertion( "nucleoside degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0009164") +AnnotationAssertion(rdfs:label "nucleoside catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (nucleotide biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways resulting in the formation of nucleotides, any nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety; may be mono-, di- or triphosphate; this definition includes cyclic-nucleotides (nucleoside cyclic phosphates).") +AnnotationAssertion( "nucleotide anabolism") +AnnotationAssertion( "nucleotide biosynthesis") +AnnotationAssertion( "nucleotide formation") +AnnotationAssertion( "nucleotide synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0009165") +AnnotationAssertion(rdfs:label "nucleotide biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (nucleotide catabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways resulting in the breakdown of nucleotides, any nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety; may be mono-, di- or triphosphate; this definition includes cyclic-nucleotides (nucleoside cyclic phosphates).") +AnnotationAssertion( "nucleotide breakdown") +AnnotationAssertion( "nucleotide catabolism") +AnnotationAssertion( "nucleotide degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0009166") +AnnotationAssertion(rdfs:label "nucleotide catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (purine ribonucleoside diphosphate metabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving purine ribonucleoside diphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with diphosphate on the sugar.") +AnnotationAssertion( "purine ribonucleoside diphosphate metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0009179") +AnnotationAssertion(rdfs:label "purine ribonucleoside diphosphate metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (purine ribonucleoside diphosphate biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of purine ribonucleoside diphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with diphosphate on the sugar.") +AnnotationAssertion( "purine ribonucleoside diphosphate anabolism") +AnnotationAssertion( "purine ribonucleoside diphosphate biosynthesis") +AnnotationAssertion( "purine ribonucleoside diphosphate formation") +AnnotationAssertion( "purine ribonucleoside diphosphate synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0009180") +AnnotationAssertion(rdfs:label "purine ribonucleoside diphosphate biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (purine ribonucleoside diphosphate catabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of purine ribonucleoside diphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with diphosphate on the sugar.") +AnnotationAssertion( "purine ribonucleoside diphosphate breakdown") +AnnotationAssertion( "purine ribonucleoside diphosphate catabolism") +AnnotationAssertion( "purine ribonucleoside diphosphate degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0009181") +AnnotationAssertion(rdfs:label "purine ribonucleoside diphosphate catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (ribonucleoside diphosphate metabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving a ribonucleoside diphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with diphosphate on the sugar.") +AnnotationAssertion( "ribonucleoside diphosphate metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0009185") +AnnotationAssertion(rdfs:label "ribonucleoside diphosphate metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (ribonucleoside diphosphate biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of a ribonucleoside diphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with diphosphate on the sugar.") +AnnotationAssertion( "ribonucleoside diphosphate anabolism") +AnnotationAssertion( "ribonucleoside diphosphate biosynthesis") +AnnotationAssertion( "ribonucleoside diphosphate formation") +AnnotationAssertion( "ribonucleoside diphosphate synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0009188") +AnnotationAssertion(rdfs:label "ribonucleoside diphosphate biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (ribonucleoside diphosphate catabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of a ribonucleoside diphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with diphosphate on the sugar.") +AnnotationAssertion( "ribonucleoside diphosphate breakdown") +AnnotationAssertion( "ribonucleoside diphosphate catabolism") +AnnotationAssertion( "ribonucleoside diphosphate degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0009191") +AnnotationAssertion(rdfs:label "ribonucleoside diphosphate catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (ribonucleoside triphosphate metabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving a ribonucleoside triphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with triphosphate on the sugar.") +AnnotationAssertion( "ribonucleoside triphosphate metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0009199") +AnnotationAssertion(rdfs:label "ribonucleoside triphosphate metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (ribonucleoside triphosphate biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of a ribonucleoside triphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with triphosphate on the sugar.") +AnnotationAssertion( "ribonucleoside triphosphate anabolism") +AnnotationAssertion( "ribonucleoside triphosphate biosynthesis") +AnnotationAssertion( "ribonucleoside triphosphate formation") +AnnotationAssertion( "ribonucleoside triphosphate synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0009201") +AnnotationAssertion(rdfs:label "ribonucleoside triphosphate biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (ribonucleoside triphosphate catabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of a ribonucleoside triphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with triphosphate on the sugar.") +AnnotationAssertion( "ribonucleoside triphosphate breakdown") +AnnotationAssertion( "ribonucleoside triphosphate catabolism") +AnnotationAssertion( "ribonucleoside triphosphate degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0009203") +AnnotationAssertion(rdfs:label "ribonucleoside triphosphate catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (purine ribonucleoside triphosphate metabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving purine ribonucleoside triphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with triphosphate on the sugar.") +AnnotationAssertion( "purine ribonucleoside triphosphate metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0009205") +AnnotationAssertion(rdfs:label "purine ribonucleoside triphosphate metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (purine ribonucleoside triphosphate biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of purine ribonucleoside triphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with triphosphate on the sugar.") +AnnotationAssertion( "purine ribonucleoside triphosphate anabolism") +AnnotationAssertion( "purine ribonucleoside triphosphate biosynthesis") +AnnotationAssertion( "purine ribonucleoside triphosphate formation") +AnnotationAssertion( "purine ribonucleoside triphosphate synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0009206") +AnnotationAssertion(rdfs:label "purine ribonucleoside triphosphate biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (purine ribonucleoside triphosphate catabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of purine ribonucleoside triphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with triphosphate on the sugar.") +AnnotationAssertion( "purine ribonucleoside triphosphate breakdown") +AnnotationAssertion( "purine ribonucleoside triphosphate catabolism") +AnnotationAssertion( "purine ribonucleoside triphosphate degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0009207") +AnnotationAssertion(rdfs:label "purine ribonucleoside triphosphate catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (glycolipid biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways resulting in the formation of glycolipid, a class of 1,2-di-O-acylglycerols joined at oxygen 3 by a glycosidic linkage to a carbohydrate part (usually a mono-, di- or tri-saccharide).") +AnnotationAssertion( "MetaCyc:PWY-401") +AnnotationAssertion( "glycolipid anabolism") +AnnotationAssertion( "glycolipid biosynthesis") +AnnotationAssertion( "glycolipid formation") +AnnotationAssertion( "glycolipid synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0009247") +AnnotationAssertion(rdfs:label "glycolipid biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + # Class: (glucan biosynthetic process) AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways resulting in the formation of glucans, polysaccharides consisting only of glucose residues.") @@ -31850,9 +60223,54 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0009250") AnnotationAssertion(rdfs:label "glucan biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) +# Class: (glucan catabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways resulting in the breakdown of glucans, polysaccharides consisting only of glucose residues.") +AnnotationAssertion( "glucan breakdown") +AnnotationAssertion( "glucan catabolism") +AnnotationAssertion( "glucan degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0009251") +AnnotationAssertion(rdfs:label "glucan catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (ribonucleotide metabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving a ribonucleotide, a compound consisting of ribonucleoside (a base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.") +AnnotationAssertion( "GO:0009121") +AnnotationAssertion( "ribonucleotide metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0009259") +AnnotationAssertion(rdfs:label "ribonucleotide metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (ribonucleotide biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of a ribonucleotide, a compound consisting of ribonucleoside (a base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.") +AnnotationAssertion( "ribonucleotide anabolism") +AnnotationAssertion( "ribonucleotide biosynthesis") +AnnotationAssertion( "ribonucleotide formation") +AnnotationAssertion( "ribonucleotide synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0009260") +AnnotationAssertion(rdfs:label "ribonucleotide biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (ribonucleotide catabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of a ribonucleotide, a compound consisting of ribonucleoside (a base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.") +AnnotationAssertion( "ribonucleotide breakdown") +AnnotationAssertion( "ribonucleotide catabolism") +AnnotationAssertion( "ribonucleotide degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0009261") +AnnotationAssertion(rdfs:label "ribonucleotide catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (response to temperature stimulus) AnnotationAssertion(Annotation( "GOC:hb") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a temperature stimulus.") @@ -31873,6 +60291,7 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0009306") AnnotationAssertion(rdfs:label "protein secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) @@ -31889,6 +60308,31 @@ AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "amine metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (amine biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom.") +AnnotationAssertion( "amine anabolism") +AnnotationAssertion( "amine biosynthesis") +AnnotationAssertion( "amine formation") +AnnotationAssertion( "amine synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0009309") +AnnotationAssertion(rdfs:label "amine biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (amine catabolic process) + +AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom.") +AnnotationAssertion( "amine breakdown") +AnnotationAssertion( "amine catabolism") +AnnotationAssertion( "amine degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0009310") +AnnotationAssertion(rdfs:label "amine catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (response to radiation) @@ -31901,6 +60345,44 @@ AnnotationAssertion(rdfs:comment "No AnnotationAssertion(rdfs:label "response to radiation") SubClassOf( ) +# Class: (phospholipid catabolic process) + +AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of phospholipids, any lipid containing phosphoric acid as a mono- or diester.") +AnnotationAssertion( "phospholipid breakdown") +AnnotationAssertion( "phospholipid catabolism") +AnnotationAssertion( "phospholipid degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0009395") +AnnotationAssertion(rdfs:label "phospholipid catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (response to water deprivation) + +AnnotationAssertion(Annotation( "GOC:lr") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a water deprivation stimulus, prolonged deprivation of water.") +AnnotationAssertion( "response to dehydration") +AnnotationAssertion( "response to drought") +AnnotationAssertion( "response to thirst") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "drought tolerance") +AnnotationAssertion( "GO:0009414") +AnnotationAssertion(rdfs:label "response to water deprivation") +SubClassOf( ) +SubClassOf( ) + +# Class: (response to water) + +AnnotationAssertion(Annotation( "GOC:jl") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of water.") +AnnotationAssertion(Annotation( "GOC:dos") "response to water stimulus") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0009415") +AnnotationAssertion(rdfs:label "response to water") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + # Class: (response to light stimulus) AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0582227089") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light.") @@ -31908,6 +60390,7 @@ AnnotationAssertion( "GO:0009416") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "response to light stimulus") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) # Class: (gamma-aminobutyric acid metabolic process) @@ -31924,9 +60407,48 @@ AnnotationAssertion( "GO:0009448") AnnotationAssertion(rdfs:comment "See also the biological process term 'neurotransmitter metabolic process ; GO:0042133'.") AnnotationAssertion(rdfs:label "gamma-aminobutyric acid metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) +# Class: (gamma-aminobutyric acid biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways resulting in the formation of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms.") +AnnotationAssertion( "4-aminobutanoate biosynthesis") +AnnotationAssertion( "4-aminobutanoate biosynthetic process") +AnnotationAssertion( "4-aminobutyrate biosynthesis") +AnnotationAssertion( "4-aminobutyrate biosynthetic process") +AnnotationAssertion( "GABA biosynthesis") +AnnotationAssertion( "GABA biosynthetic process") +AnnotationAssertion( "gamma-aminobutyric acid anabolism") +AnnotationAssertion( "gamma-aminobutyric acid biosynthesis") +AnnotationAssertion( "gamma-aminobutyric acid formation") +AnnotationAssertion( "gamma-aminobutyric acid synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0009449") +AnnotationAssertion(rdfs:comment "See also the biological process term 'neurotransmitter biosynthetic process ; GO:0042136'.") +AnnotationAssertion(rdfs:label "gamma-aminobutyric acid biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (gamma-aminobutyric acid catabolic process) + +AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways resulting in the breakdown of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms.") +AnnotationAssertion( "MetaCyc:4AMINOBUTMETAB-PWY") +AnnotationAssertion( "4-aminobutanoate catabolic process") +AnnotationAssertion( "4-aminobutanoate catabolism") +AnnotationAssertion( "4-aminobutyrate catabolic process") +AnnotationAssertion( "4-aminobutyrate catabolism") +AnnotationAssertion( "GABA catabolic process") +AnnotationAssertion( "GABA catabolism") +AnnotationAssertion( "gamma-aminobutyric acid breakdown") +AnnotationAssertion( "gamma-aminobutyric acid catabolism") +AnnotationAssertion( "gamma-aminobutyric acid degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0009450") +AnnotationAssertion(rdfs:comment "See also the biological process term 'neurotransmitter catabolic process ; GO:0042135'.") +AnnotationAssertion(rdfs:label "gamma-aminobutyric acid catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (fertilization) AnnotationAssertion(Annotation( "GOC:tb") Annotation( "ISBN:0198506732") "The union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy).") @@ -31936,6 +60458,7 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0009566") AnnotationAssertion(rdfs:label "fertilization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf( ObjectSomeValuesFrom( )) # Class: (detection of external stimulus) @@ -32051,6 +60574,29 @@ AnnotationAssertion(rdfs:label "resp SubClassOf( ) SubClassOf( ) +# Class: (response to bacterium) + +AnnotationAssertion(Annotation( "GOC:hb") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a bacterium.") +AnnotationAssertion( "GO:0009618") +AnnotationAssertion( "GO:0009680") +AnnotationAssertion( "response to bacteria") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0009617") +AnnotationAssertion(rdfs:label "response to bacterium") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (response to fungus) + +AnnotationAssertion(Annotation( "GOC:hb") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a fungus.") +AnnotationAssertion( "GO:0009621") +AnnotationAssertion( "response to fungi") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0009620") +AnnotationAssertion(rdfs:label "response to fungus") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + # Class: (response to abiotic stimulus) AnnotationAssertion(Annotation( "GOC:hb") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abiotic (not derived from living organisms) stimulus.") @@ -32099,6 +60645,7 @@ AnnotationAssertion(rdfs:label "anat SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) DisjointClasses( ) +DisjointClasses( ) # Class: (catechol-containing compound metabolic process) @@ -32108,8 +60655,89 @@ AnnotationAssertion( "catechol metabolism") AnnotationAssertion( "GO:0009712") AnnotationAssertion(rdfs:label "catechol-containing compound metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (catechol-containing compound biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways resulting in the formation of catechol-containing compounds. Catechol is a compound containing a pyrocatechol nucleus or substituent.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "catechol anabolism") +AnnotationAssertion( "catechol biosynthesis") +AnnotationAssertion( "catechol biosynthetic process") +AnnotationAssertion( "catechol formation") +AnnotationAssertion( "catechol synthesis") +AnnotationAssertion( "GO:0009713") +AnnotationAssertion(rdfs:label "catechol-containing compound biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (response to endogenous stimulus) + +AnnotationAssertion(Annotation( "GOC:sm") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus arising within the organism.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0009719") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.") +AnnotationAssertion(rdfs:label "response to endogenous stimulus") +SubClassOf( ) + +# Class: (response to hormone) + +AnnotationAssertion(Annotation( "GOC:jl") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hormone stimulus.") +AnnotationAssertion(Annotation( "GOC:dos") "response to hormone stimulus") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "growth regulator") +AnnotationAssertion( "GO:0009725") +AnnotationAssertion(rdfs:label "response to hormone") +SubClassOf( ) +SubClassOf( ) + +# Class: (response to carbohydrate) + +AnnotationAssertion(Annotation( "GOC:jl") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbohydrate stimulus.") +AnnotationAssertion(Annotation( "GOC:dos") "response to carbohydrate stimulus") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0009743") +AnnotationAssertion(rdfs:label "response to carbohydrate") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (response to hexose) + +AnnotationAssertion(Annotation( "GOC:jl") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hexose stimulus.") +AnnotationAssertion(Annotation( "GOC:dos") "response to hexose stimulus") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0009746") +AnnotationAssertion(rdfs:label "response to hexose") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (response to glucose) + +AnnotationAssertion(Annotation( "GOC:jl") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucose stimulus.") +AnnotationAssertion(Annotation( "GOC:dos") "response to glucose stimulus") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0009749") +AnnotationAssertion(rdfs:label "response to glucose") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (hormone-mediated signaling pathway) + +AnnotationAssertion(Annotation( "GOC:sm") "The series of molecular signals mediated by the detection of a hormone.") +AnnotationAssertion( "hormone mediated signalling") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0009755") +AnnotationAssertion(rdfs:label "hormone-mediated signaling pathway") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (regulation of asymmetric cell division) + +AnnotationAssertion(Annotation( "GOC:lr") "Any process that modulates the frequency, rate or extent of asymmetric cell division.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0009786") +AnnotationAssertion(rdfs:label "regulation of asymmetric cell division") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (embryo development) AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "GOC:isa_complete") Annotation( "GOC:mtg_sensu") "The process whose specific outcome is the progression of an embryo from its formation until the end of its embryonic life stage. The end of the embryonic stage is organism-specific. For example, for mammals, the process would begin with zygote formation and end with birth. For insects, the process would begin at zygote formation and end with larval hatching. For plant zygotic embryos, this would be from zygote formation to the end of seed dormancy. For plant vegetative embryos, this would be from the initial determination of the cell or group of cells to form an embryo until the point when the embryo becomes independent of the parent plant.") @@ -32124,6 +60752,7 @@ AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "embryo development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ) @@ -32149,6 +60778,73 @@ SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectAllValuesFrom( )) +# Class: (axis specification) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:go_curators") Annotation( "GOC:isa_complete") "The establishment, maintenance and elaboration of a pattern along a line or around a point.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "axis determination") +AnnotationAssertion( "GO:0009798") +AnnotationAssertion(rdfs:label "axis specification") +SubClassOf( ) + +# Class: (alkaloid metabolic process) + +AnnotationAssertion(Annotation( "GOC:lr") Annotation( "ISBN:0122146743") "The chemical reactions and pathways involving alkaloids, nitrogen containing natural products which are not otherwise classified as peptides, nonprotein amino acids, amines, cyanogenic glycosides, glucosinolates, cofactors, phytohormones or primary metabolites (such as purine or pyrimidine bases).") +AnnotationAssertion( "alkaloid metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0009820") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "alkaloid metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (alkaloid biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:lr") Annotation( "ISBN:0122146743") "The chemical reactions and pathways resulting in the formation of alkaloids, nitrogen-containing natural products which are not otherwise classified as nonprotein amino acids, amines, peptides, amines, cyanogenic glycosides, glucosinolates, cofactors, phytohormones, or primary metabolite (such as purine or pyrimidine bases).") +AnnotationAssertion( "UM-BBD_enzymeID:e0711") +AnnotationAssertion( "alkaloid anabolism") +AnnotationAssertion( "alkaloid biosynthesis") +AnnotationAssertion( "alkaloid formation") +AnnotationAssertion( "alkaloid synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0009821") +AnnotationAssertion(rdfs:label "alkaloid biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (alkaloid catabolic process) + +AnnotationAssertion(Annotation( "GOC:lr") Annotation( "ISBN:0122146743") "The chemical reactions and pathways resulting in the breakdown of alkaloids, nitrogen containing natural products not otherwise classified as peptides, nonprotein amino acids, amines, cyanogenic glycosides, glucosinolates, cofactors, phytohormones or primary metabolites (such as purine or pyrimidine bases).") +AnnotationAssertion( "alkaloid breakdown") +AnnotationAssertion( "alkaloid catabolism") +AnnotationAssertion( "alkaloid degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0009822") +AnnotationAssertion(rdfs:label "alkaloid catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (embryonic pattern specification) + +AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0521436125") "The process that results in the patterns of cell differentiation that will arise in an embryo.") +AnnotationAssertion( "embryonic pattern biosynthesis") +AnnotationAssertion( "embryonic pattern formation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "ventral/lateral system") +AnnotationAssertion( "GO:0009880") +AnnotationAssertion(rdfs:label "embryonic pattern specification") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (post-embryonic animal morphogenesis) + +AnnotationAssertion(Annotation( "GOC:go_curators") "The process, occurring after animal embryonic development, by which anatomical structures are generated and organized.") +AnnotationAssertion( "post-embryonic morphogenesis of an anatomical structure") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0009886") +AnnotationAssertion(rdfs:label "post-embryonic animal morphogenesis") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (animal organ morphogenesis) AnnotationAssertion(Annotation( "GOC:dgh") Annotation( "GOC:go_curators") Annotation( "ISBN:0471245208") Annotation( "ISBN:0721662544") "Morphogenesis of an animal organ. An organ is defined as a tissue or set of tissues that work together to perform a specific function or functions. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.") @@ -32156,6 +60852,7 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0009887") AnnotationAssertion(rdfs:label "animal organ morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) @@ -32174,6 +60871,7 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0009888") AnnotationAssertion(rdfs:label "tissue development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) @@ -32193,6 +60891,139 @@ DisjointClasses( ObjectSomeValuesFrom DisjointClasses( ObjectSomeValuesFrom( )) DisjointClasses( ObjectSomeValuesFrom( )) +# Class: (regulation of biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances.") +AnnotationAssertion( "regulation of anabolism") +AnnotationAssertion( "regulation of biosynthesis") +AnnotationAssertion( "regulation of formation") +AnnotationAssertion( "regulation of synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0009889") +AnnotationAssertion(rdfs:label "regulation of biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (negative regulation of biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the rate of the chemical reactions and pathways resulting in the formation of substances.") +AnnotationAssertion( "down regulation of biosynthetic process") +AnnotationAssertion( "down-regulation of biosynthetic process") +AnnotationAssertion( "downregulation of biosynthetic process") +AnnotationAssertion( "negative regulation of anabolism") +AnnotationAssertion( "negative regulation of biosynthesis") +AnnotationAssertion( "negative regulation of formation") +AnnotationAssertion( "negative regulation of synthesis") +AnnotationAssertion( "inhibition of biosynthetic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0009890") +AnnotationAssertion(rdfs:label "negative regulation of biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances.") +AnnotationAssertion( "positive regulation of anabolism") +AnnotationAssertion( "positive regulation of biosynthesis") +AnnotationAssertion( "positive regulation of formation") +AnnotationAssertion( "positive regulation of synthesis") +AnnotationAssertion( "up regulation of biosynthetic process") +AnnotationAssertion( "up-regulation of biosynthetic process") +AnnotationAssertion( "upregulation of biosynthetic process") +AnnotationAssertion( "activation of biosynthetic process") +AnnotationAssertion( "stimulation of biosynthetic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0009891") +AnnotationAssertion(rdfs:label "positive regulation of biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of metabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.") +AnnotationAssertion( "GO:0044252") +AnnotationAssertion( "down regulation of metabolic process") +AnnotationAssertion( "down-regulation of metabolic process") +AnnotationAssertion( "downregulation of metabolic process") +AnnotationAssertion( "negative regulation of metabolism") +AnnotationAssertion( "negative regulation of organismal metabolism") +AnnotationAssertion( "inhibition of metabolic process") +AnnotationAssertion( "inhibition of organismal metabolic process") +AnnotationAssertion( "negative regulation of multicellular organismal metabolic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0009892") +AnnotationAssertion(rdfs:label "negative regulation of metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of metabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.") +AnnotationAssertion( "GO:0044253") +AnnotationAssertion( "positive regulation of metabolism") +AnnotationAssertion( "up regulation of metabolic process") +AnnotationAssertion( "up-regulation of metabolic process") +AnnotationAssertion( "upregulation of metabolic process") +AnnotationAssertion( "activation of metabolic process") +AnnotationAssertion( "positive regulation of multicellular organismal metabolic process") +AnnotationAssertion( "positive regulation of organismal metabolism") +AnnotationAssertion( "stimulation of metabolic process") +AnnotationAssertion( "stimulation of organismal metabolic process") +AnnotationAssertion( "up-regulation of organismal metabolic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0009893") +AnnotationAssertion(rdfs:label "positive regulation of metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of catabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of substances.") +AnnotationAssertion( "regulation of breakdown") +AnnotationAssertion( "regulation of catabolism") +AnnotationAssertion( "regulation of degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0009894") +AnnotationAssertion(rdfs:label "regulation of catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (negative regulation of catabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances.") +AnnotationAssertion( "down regulation of catabolic process") +AnnotationAssertion( "down-regulation of catabolic process") +AnnotationAssertion( "downregulation of catabolic process") +AnnotationAssertion( "negative regulation of breakdown") +AnnotationAssertion( "negative regulation of catabolism") +AnnotationAssertion( "negative regulation of degradation") +AnnotationAssertion( "inhibition of catabolic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0009895") +AnnotationAssertion(rdfs:label "negative regulation of catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of catabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances.") +AnnotationAssertion( "positive regulation of breakdown") +AnnotationAssertion( "positive regulation of catabolism") +AnnotationAssertion( "positive regulation of degradation") +AnnotationAssertion( "up regulation of catabolic process") +AnnotationAssertion( "up-regulation of catabolic process") +AnnotationAssertion( "upregulation of catabolic process") +AnnotationAssertion( "activation of catabolic process") +AnnotationAssertion( "stimulation of catabolic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0009896") +AnnotationAssertion(rdfs:label "positive regulation of catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + # Class: (epidermal cell differentiation) AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:go_curators") Annotation( "GOC:mtg_sensu") Annotation( "GOC:sdb_2009") Annotation( "GOC:tb") "The process in which a relatively unspecialized cell acquires specialized features of an epidermal cell, any of the cells making up the epidermis.") @@ -32201,6 +61032,7 @@ AnnotationAssertion( "GOC:kmv") Annotation( "GOC:rk") "hypodermal cell differentiation") AnnotationAssertion( "GO:0009913") AnnotationAssertion(rdfs:label "epidermal cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) @@ -32214,6 +61046,78 @@ AnnotationAssertion(rdfs:label "horm SubClassOf( ) SubClassOf( ) +# Class: (anterior/posterior axis specification) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:go_curators") Annotation( "GOC:tb") "The establishment, maintenance and elaboration of the anterior/posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism.") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") "anterior/posterior axis determination") +AnnotationAssertion( "GO:0009948") +AnnotationAssertion(rdfs:label "anterior/posterior axis specification") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (anterior/posterior pattern specification) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:go_curators") Annotation( "GOC:isa_complete") Annotation( "GOC:tb") "The regionalization process in which specific areas of cell differentiation are determined along the anterior-posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "anterior/posterior pattern formation") +AnnotationAssertion( "GO:0009952") +AnnotationAssertion(rdfs:label "anterior/posterior pattern specification") +SubClassOf( ) + +# Class: (regulation of signal transduction) + +AnnotationAssertion(Annotation( "GOC:sm") "Any process that modulates the frequency, rate or extent of signal transduction.") +AnnotationAssertion( "GO:0035466") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "regulation of signaling pathway") +AnnotationAssertion(Annotation( "GOC:mah") "regulation of signalling pathway") +AnnotationAssertion( "GO:0009966") +AnnotationAssertion(rdfs:label "regulation of signal transduction") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of signal transduction) + +AnnotationAssertion(Annotation( "GOC:sm") "Any process that activates or increases the frequency, rate or extent of signal transduction.") +AnnotationAssertion( "GO:0035468") +AnnotationAssertion( "up regulation of signal transduction") +AnnotationAssertion( "up-regulation of signal transduction") +AnnotationAssertion( "upregulation of signal transduction") +AnnotationAssertion( "activation of signal transduction") +AnnotationAssertion( "stimulation of signal transduction") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "positive regulation of signaling pathway") +AnnotationAssertion(Annotation( "GOC:mah") "positive regulation of signalling pathway") +AnnotationAssertion( "GO:0009967") +AnnotationAssertion(rdfs:label "positive regulation of signal transduction") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of signal transduction) + +AnnotationAssertion(Annotation( "GOC:sm") "Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction.") +AnnotationAssertion( "GO:0035467") +AnnotationAssertion( "down regulation of signal transduction") +AnnotationAssertion( "down-regulation of signal transduction") +AnnotationAssertion( "downregulation of signal transduction") +AnnotationAssertion( "inhibition of signal transduction") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "negative regulation of signaling pathway") +AnnotationAssertion(Annotation( "GOC:mah") "negative regulation of signalling pathway") +AnnotationAssertion( "GO:0009968") +AnnotationAssertion(rdfs:label "negative regulation of signal transduction") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + # Class: (cellular process) AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "GOC:isa_complete") "Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.") @@ -32235,6 +61139,75 @@ AnnotationAssertion(rdfs:label "cell SubClassOf( ) DisjointClasses( ) +# Class: (intracellular water homeostasis) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "A homeostatic process involved in the maintenance of a steady state level of water within a cell.") +AnnotationAssertion( "cellular water homeostasis") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "cellular osmoregulation") +AnnotationAssertion( "GO:0009992") +AnnotationAssertion(rdfs:label "intracellular water homeostasis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (oocyte differentiation) + +AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "GOC:mtg_sensu") "The process in which a relatively unspecialized immature germ cell acquires the specialized features of a mature female gamete.") +AnnotationAssertion( "oocyte cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0009994") +AnnotationAssertion(rdfs:label "oocyte differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (glial cell differentiation) + +AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "GOC:mtg_sensu") "The process in which a relatively unspecialized cell acquires the specialized features of a glial cell.") +AnnotationAssertion( "GO:0007404") +AnnotationAssertion( "GO:0043360") +AnnotationAssertion( "glia cell differentiation") +AnnotationAssertion( "neuroglia differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010001") +AnnotationAssertion(rdfs:label "glial cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectAllValuesFrom( )) + +# Class: (cardioblast differentiation) + +AnnotationAssertion(Annotation( "GOC:go_curators") "The process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.") +AnnotationAssertion(Annotation( "GOC:mtg_heart") "cardiac precursor cell differentiation") +AnnotationAssertion( "cardioblast cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "cardiomyocyte generation") +AnnotationAssertion( "GO:0010002") +AnnotationAssertion(rdfs:label "cardioblast differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (gastrulation involving germ band extension) + +AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "GOC:mtg_sensu") "A complex and coordinated series of cellular movements, including germ band extension, that occurs at the end of cleavage during embryonic development. An example of this process is found in Drosophila melanogaster.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010004") +AnnotationAssertion(rdfs:label "gastrulation involving germ band extension") +SubClassOf( ) + +# Class: (meiotic chromosome condensation) + +AnnotationAssertion(Annotation( "PMID:10072401") "Compaction of chromatin structure prior to meiosis in eukaryotic cells.") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "chromosome condensation involved in meiotic cell cycle") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010032") +AnnotationAssertion(rdfs:label "meiotic chromosome condensation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + # Class: (response to organic substance) AnnotationAssertion(Annotation( "GOC:sm") Annotation( "PMID:23356676") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic substance stimulus.") @@ -32243,6 +61216,180 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0010033") AnnotationAssertion(rdfs:label "response to organic substance") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (response to acetate) + +AnnotationAssertion(Annotation( "GOC:sm") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetate stimulus.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010034") +AnnotationAssertion(rdfs:label "response to acetate") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (response to inorganic substance) + +AnnotationAssertion(Annotation( "GOC:sm") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inorganic substance stimulus.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010035") +AnnotationAssertion(rdfs:label "response to inorganic substance") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (response to carbon dioxide) + +AnnotationAssertion(Annotation( "GOC:sm") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbon dioxide (CO2) stimulus.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010037") +AnnotationAssertion(rdfs:label "response to carbon dioxide") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (response to metal ion) + +AnnotationAssertion(Annotation( "GOC:sm") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metal ion stimulus.") +AnnotationAssertion( "response to metal") +AnnotationAssertion( "response to heavy metal") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "heavy metal sensitivity/resistance") +AnnotationAssertion( "GO:0010038") +AnnotationAssertion(rdfs:label "response to metal ion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (response to iron ion) + +AnnotationAssertion(Annotation( "GOC:sm") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron ion stimulus.") +AnnotationAssertion( "response to iron") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010039") +AnnotationAssertion(rdfs:label "response to iron ion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (zygote asymmetric cell division) + +AnnotationAssertion(Annotation( "GOC:tb") "The division of the zygote into two daughter cells that will adopt developmentally distinct potentials.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "zygote asymmetric cytokinesis") +AnnotationAssertion( "GO:0010070") +AnnotationAssertion(rdfs:label "zygote asymmetric cell division") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (formation of animal organ boundary) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:isa_complete") Annotation( "PMID:9611175") "The regionalization process that specifies animal organ primordium boundaries resulting in a restriction of organogenesis to a limited spatial domain and keeping the organ separate from surrounding tissues.") +AnnotationAssertion( "GO:0048862") +AnnotationAssertion( "organ boundary specification") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010160") +AnnotationAssertion(rdfs:label "formation of animal organ boundary") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (body morphogenesis) + +AnnotationAssertion(Annotation( "GOC:ems") Annotation( "ISBN:0140512888") "The process in which the anatomical structures of the soma are generated and organized.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010171") +AnnotationAssertion(rdfs:label "body morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (response to chitin) + +AnnotationAssertion(Annotation( "GOC:sm") "A process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chitin stimulus.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010200") +AnnotationAssertion(rdfs:label "response to chitin") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (vascular transport) + +AnnotationAssertion(Annotation( "GOC:sm") "The directed movement of substances, into, out of or within a cell, either in a vascular tissue or in the vascular membrane.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010232") +AnnotationAssertion(rdfs:label "vascular transport") +SubClassOf( ) +SubClassOf( ) + +# Class: (response to organonitrogen compound) + +AnnotationAssertion(Annotation( "PMID:9869419") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organonitrogen stimulus. An organonitrogen compound is formally a compound containing at least one carbon-nitrogen bond.") +AnnotationAssertion( "response to organic nitrogen") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010243") +AnnotationAssertion(rdfs:label "response to organonitrogen compound") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (endomembrane system organization) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:sm") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endomembrane system.") +AnnotationAssertion( "endomembrane organization") +AnnotationAssertion(Annotation( "GOC:mah") "endomembrane system organisation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010256") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "endomembrane system organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (membrane invagination) + +AnnotationAssertion(Annotation( "GOC:tb") "The infolding of a membrane.") +AnnotationAssertion( "jl") +AnnotationAssertion( "2013-12-02T13:58:34Z") +AnnotationAssertion( "GO:1902534") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "single-organism membrane invagination") +AnnotationAssertion( "GO:0010324") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "membrane invagination") +SubClassOf( ) + +# Class: (regulation of cell fate commitment) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the frequency, rate or extent of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010453") +AnnotationAssertion(rdfs:label "regulation of cell fate commitment") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of cell fate commitment) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that stops, prevents or reduces the frequency or rate of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010454") +AnnotationAssertion(rdfs:label "negative regulation of cell fate commitment") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (positive regulation of cell fate commitment) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that activates, maintains or increases the frequency or rate of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010455") +AnnotationAssertion(rdfs:label "positive regulation of cell fate commitment") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (cell proliferation in dorsal spinal cord) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "The multiplication or reproduction of cells, resulting in the expansion of the dorsal spinal cord cell population.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010456") +AnnotationAssertion(rdfs:label "cell proliferation in dorsal spinal cord") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (mesenchymal cell proliferation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010463") +AnnotationAssertion(rdfs:label "mesenchymal cell proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) # Class: (regulation of mesenchymal cell proliferation) @@ -32250,6 +61397,7 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:0010464") AnnotationAssertion(rdfs:label "regulation of mesenchymal cell proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) # Class: (gene expression) @@ -32264,14 +61412,846 @@ AnnotationAssertion( "gene expression") SubClassOf( ) +# Class: (regulation of gene expression) + +AnnotationAssertion(Annotation( "GOC:txnOH-2018") "Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA).") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/22557"^^xsd:anyURI) +AnnotationAssertion( "Wikipedia:Regulation_of_gene_expression") +AnnotationAssertion( "regulation of protein expression") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:cjm") "gene regulation") +AnnotationAssertion( "regulation of gene product expression") +AnnotationAssertion( "GO:0010468") +AnnotationAssertion(rdfs:comment "This class covers any process that regulates the rate of production of a mature gene product, and so includes processes that regulate that rate by regulating the level, stability or availability of intermediates in the process of gene expression. For example, it covers any process that regulates the level, stability or availability of mRNA or circRNA for translation and thereby regulates the rate of production of the encoded protein via translation.") +AnnotationAssertion(rdfs:label "regulation of gene expression") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of signaling receptor activity) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the frequency, rate or extent of a signaling receptor activity. Receptor activity is when a molecule combines with an extracellular or intracellular messenger to initiate a change in cell activity.") +AnnotationAssertion( "regulation of receptor activity") +AnnotationAssertion( "regulation of signalling receptor activity") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010469") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "regulation of signaling receptor activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of gastrulation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the rate or extent of gastrulation. Gastrulation is the complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010470") +AnnotationAssertion(rdfs:label "regulation of gastrulation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (epidermal cell division) + +AnnotationAssertion(Annotation( "PMID:17450124") "Any process resulting in the physical partitioning and separation of an epidermal cell, any of the cells making up the epidermis, into daughter cells.") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:kmv") Annotation( "GOC:rk") "hypodermal cell division") +AnnotationAssertion( "GO:0010481") +AnnotationAssertion(rdfs:label "epidermal cell division") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of epidermal cell division) + +AnnotationAssertion(Annotation( "PMID:17450124") "Any process that modulates the frequency, rate or extent of the physical partitioning and separation of an epidermal cell into daughter cells. An epidermal cell is any of the cells that make up the epidermis.") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:kmv") Annotation( "GOC:rk") "regulation of hypodermal cell division") +AnnotationAssertion( "GO:0010482") +AnnotationAssertion(rdfs:label "regulation of epidermal cell division") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (intercellular transport) + +AnnotationAssertion(Annotation( "GOC:dhl") "The movement of substances between cells.") +AnnotationAssertion( "jl") +AnnotationAssertion( "2013-12-19T13:24:56Z") +AnnotationAssertion( "GO:1902585") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "single organism intercellular transport") +AnnotationAssertion( "single-organism intercellular transport") +AnnotationAssertion( "GO:0010496") +AnnotationAssertion(rdfs:label "intercellular transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of platelet activation) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010543") +AnnotationAssertion(rdfs:label "regulation of platelet activation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of platelet activation) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that decreases the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010544") +AnnotationAssertion(rdfs:label "negative regulation of platelet activation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of membrane disassembly) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the frequency, rate or extent of membrane disassembly.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010549") +AnnotationAssertion(rdfs:label "regulation of membrane disassembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of macromolecule biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010556") +AnnotationAssertion(rdfs:label "regulation of macromolecule biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of macromolecule biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that increases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010557") +AnnotationAssertion(rdfs:label "positive regulation of macromolecule biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of macromolecule biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that decreases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010558") +AnnotationAssertion(rdfs:label "negative regulation of macromolecule biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of glycoprotein biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010559") +AnnotationAssertion(rdfs:label "regulation of glycoprotein biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of glycoprotein biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that increases the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010560") +AnnotationAssertion(rdfs:label "positive regulation of glycoprotein biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of glycoprotein biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that decreases the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010561") +AnnotationAssertion(rdfs:label "negative regulation of glycoprotein biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of phosphorus metabolic process) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010562") +AnnotationAssertion(rdfs:label "positive regulation of phosphorus metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of phosphorus metabolic process) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010563") +AnnotationAssertion(rdfs:label "negative regulation of phosphorus metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of cell cycle process) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010564") +AnnotationAssertion(rdfs:label "regulation of cell cycle process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of cellular ketone metabolic process) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the chemical reactions and pathways involving any of a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010565") +AnnotationAssertion(rdfs:label "regulation of cellular ketone metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of ketone biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of a ketone, carried out by individual cells.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010566") +AnnotationAssertion(rdfs:label "regulation of ketone biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of ketone catabolic process) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a ketone, carried out by individual cells.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010567") +AnnotationAssertion(rdfs:label "regulation of ketone catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of platelet activation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:sl") Annotation( "GOC:tb") "Any process that increases the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010572") +AnnotationAssertion(rdfs:label "positive regulation of platelet activation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of endothelial cell migration) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010594") +AnnotationAssertion(rdfs:label "regulation of endothelial cell migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of endothelial cell migration) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that increases the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010595") +AnnotationAssertion(rdfs:label "positive regulation of endothelial cell migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of endothelial cell migration) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that decreases the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010596") +AnnotationAssertion(rdfs:label "negative regulation of endothelial cell migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of macromolecule metabolic process) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010604") +AnnotationAssertion(rdfs:label "positive regulation of macromolecule metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of macromolecule metabolic process) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010605") +AnnotationAssertion(rdfs:label "negative regulation of macromolecule metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (post-transcriptional regulation of gene expression) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the frequency, rate or extent of gene expression after the production of an RNA transcript.") +AnnotationAssertion( "posttranscriptional regulation of gene expression") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010608") +AnnotationAssertion(rdfs:label "post-transcriptional regulation of gene expression") +SubClassOf( ) + +# Class: (regulation of cardiac muscle hypertrophy) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010611") +AnnotationAssertion(rdfs:label "regulation of cardiac muscle hypertrophy") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of cardiac muscle adaptation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the rate, extent or frequency of the process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010612") +AnnotationAssertion(rdfs:label "regulation of cardiac muscle adaptation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of cardiac muscle hypertrophy) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that increases the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010613") +AnnotationAssertion(rdfs:label "positive regulation of cardiac muscle hypertrophy") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of cardiac muscle hypertrophy) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that decreases the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010614") +AnnotationAssertion(rdfs:label "negative regulation of cardiac muscle hypertrophy") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of cardiac muscle adaptation) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that increases the rate, extent or frequency of the process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010615") +AnnotationAssertion(rdfs:label "positive regulation of cardiac muscle adaptation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of cardiac muscle adaptation) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that decreases the rate, extent or frequency of the process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010616") +AnnotationAssertion(rdfs:label "negative regulation of cardiac muscle adaptation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (programmed cell death involved in cell development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:tb") "The activation of endogenous cellular processes that result in the death of a cell as part of its development.") +AnnotationAssertion( "developmental programmed cell death") +AnnotationAssertion( "programmed cell death involved in development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010623") +AnnotationAssertion(rdfs:comment "This process is part of the natural developmental program of some cell types, but it does not always happen as part of the development or shaping of a gross anatomical structure.") +AnnotationAssertion(rdfs:label "programmed cell death involved in cell development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of Schwann cell proliferation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:sl") Annotation( "GOC:tb") "Any process that modulates the frequency or rate of multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010624") +AnnotationAssertion(rdfs:label "regulation of Schwann cell proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of Schwann cell proliferation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:sl") Annotation( "GOC:tb") "Any process that increases the frequency or rate of the multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010625") +AnnotationAssertion(rdfs:label "positive regulation of Schwann cell proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of Schwann cell proliferation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:sl") Annotation( "GOC:tb") "Any process that decreases the frequency or extent of the multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010626") +AnnotationAssertion(rdfs:label "negative regulation of Schwann cell proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of gene expression) + +AnnotationAssertion(Annotation( "GOC:txnOH-2018") "Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA).") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/22557"^^xsd:anyURI) +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010628") +AnnotationAssertion(rdfs:label "positive regulation of gene expression") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of gene expression) + +AnnotationAssertion(Annotation( "GOC:txnOH-2018") "Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA).") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/22557"^^xsd:anyURI) +AnnotationAssertion( "biological_process") +AnnotationAssertion( "gene silencing") +AnnotationAssertion( "GO:0010629") +AnnotationAssertion(rdfs:comment "This term covers any process that negatively regulates the rate of production of a mature gene product, and so includes processes that negatively regulate that rate by reducing the level, stability or availability of intermediates in the process of gene expression. For example, it covers any process that reduces the level, stability or availability of mRNA or circRNA for translation and thereby reduces the rate of production of the encoded protein via translation.") +AnnotationAssertion(rdfs:label "negative regulation of gene expression") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (epithelial cell migration) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "The orderly movement of an epithelial cell from one site to another, often during the development of a multicellular organism.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010631") +AnnotationAssertion(rdfs:label "epithelial cell migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (regulation of epithelial cell migration) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the frequency, rate or extent of epithelial cell migration.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010632") +AnnotationAssertion(rdfs:label "regulation of epithelial cell migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (negative regulation of epithelial cell migration) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that stops, prevents, or reduces the frequency, rate or extent of epithelial cell migration.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010633") +AnnotationAssertion(rdfs:label "negative regulation of epithelial cell migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (positive regulation of epithelial cell migration) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that activates or increases the frequency, rate or extent of epithelial cell migration.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010634") +AnnotationAssertion(rdfs:label "positive regulation of epithelial cell migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of organelle organization) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle.") +AnnotationAssertion(Annotation( "GOC:mah") "positive regulation of organelle organisation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:mah") "positive regulation of organelle organization and biogenesis") +AnnotationAssertion( "GO:0010638") +AnnotationAssertion(rdfs:label "positive regulation of organelle organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of organelle organization) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that decreases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle.") +AnnotationAssertion(Annotation( "GOC:mah") "negative regulation of organelle organisation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:mah") "negative regulation of organelle organization and biogenesis") +AnnotationAssertion( "GO:0010639") +AnnotationAssertion(rdfs:label "negative regulation of organelle organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + # Class: (regulation of cell communication) AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0010646") AnnotationAssertion(rdfs:label "regulation of cell communication") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (positive regulation of cell communication) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that increases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010647") +AnnotationAssertion(rdfs:label "positive regulation of cell communication") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of cell communication) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that decreases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010648") +AnnotationAssertion(rdfs:label "negative regulation of cell communication") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of muscle cell apoptotic process) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:tb") "Any process that decreases the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death.") +AnnotationAssertion( "negative regulation of muscle cell apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010656") +AnnotationAssertion(rdfs:label "negative regulation of muscle cell apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (muscle cell apoptotic process) + +AnnotationAssertion(Annotation( "CL:0000187") Annotation( "GOC:dph") Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:tb") "A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a muscle cell and result in its death. A muscle cell is a mature contractile cell, commonly known as a myocyte, that forms one of three kinds of muscle.") +AnnotationAssertion( "muscle cell apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010657") +AnnotationAssertion(rdfs:label "muscle cell apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectAllValuesFrom( )) + +# Class: (striated muscle cell apoptotic process) + +AnnotationAssertion(Annotation( "CL:0000737") Annotation( "GOC:dph") Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:tb") "A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a striated muscle cell and result in its death. Striated muscle cells make up striated muscle fibers which are divided by transverse bands into striations.") +AnnotationAssertion( "striated muscle cell apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010658") +AnnotationAssertion(rdfs:label "striated muscle cell apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (cardiac muscle cell apoptotic process) + +AnnotationAssertion(Annotation( "CL:0000746") Annotation( "GOC:dph") Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:tb") "A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a cardiac muscle cell and result in its death. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction.") +AnnotationAssertion( "cardiac muscle cell apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010659") +AnnotationAssertion(rdfs:label "cardiac muscle cell apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of muscle cell apoptotic process) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:tb") "Any process that modulates the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death.") +AnnotationAssertion( "regulation of muscle cell apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010660") +AnnotationAssertion(rdfs:label "regulation of muscle cell apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of muscle cell apoptotic process) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:tb") "Any process that increases the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death.") +AnnotationAssertion( "positive regulation of muscle cell apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010661") +AnnotationAssertion(rdfs:label "positive regulation of muscle cell apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of striated muscle cell apoptotic process) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:tb") "Any process that modulates the rate or extent of striated muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a striated muscle cell and result in its death.") +AnnotationAssertion( "regulation of striated muscle cell apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010662") +AnnotationAssertion(rdfs:label "regulation of striated muscle cell apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of striated muscle cell apoptotic process) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:tb") "Any process that increases the rate or extent of striated muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a striated muscle cell and result in its death.") +AnnotationAssertion( "positive regulation of striated muscle cell apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010663") +AnnotationAssertion(rdfs:label "positive regulation of striated muscle cell apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of striated muscle cell apoptotic process) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:rl") Annotation( "GOC:tb") "Any process that decreases the rate or extent of striated muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a striated muscle cell and result in its death.") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:rl") Annotation( "GOC:tb") "down regulation of striated muscle cell apoptosis") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:rl") Annotation( "GOC:tb") "down-regulation of striated muscle cell apoptosis") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:rl") Annotation( "GOC:tb") "downregulation of striated muscle cell apoptosis") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:rl") Annotation( "GOC:tb") "inhibition of striated muscle cell apoptosis") +AnnotationAssertion( "negative regulation of striated muscle cell apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010664") +AnnotationAssertion(rdfs:label "negative regulation of striated muscle cell apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of cardiac muscle cell apoptotic process) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:tb") "Any process that modulates the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death.") +AnnotationAssertion( "regulation of cardiac muscle cell apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010665") +AnnotationAssertion(rdfs:label "regulation of cardiac muscle cell apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of cardiac muscle cell apoptotic process) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:tb") "Any process that increases the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death.") +AnnotationAssertion( "positive regulation of cardiac muscle cell apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010666") +AnnotationAssertion(rdfs:label "positive regulation of cardiac muscle cell apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of cardiac muscle cell apoptotic process) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:rl") Annotation( "GOC:tb") "Any process that decreases the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death.") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:rl") Annotation( "GOC:tb") "down regulation of cardiac muscle cell apoptosis") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:rl") Annotation( "GOC:tb") "down-regulation of cardiac muscle cell apoptosis") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:rl") Annotation( "GOC:tb") "downregulation of cardiac muscle cell apoptosis") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:rl") Annotation( "GOC:tb") "inhibition of cardiac muscle cell apoptosis") +AnnotationAssertion( "negative regulation of cardiac muscle cell apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010667") +AnnotationAssertion(rdfs:label "negative regulation of cardiac muscle cell apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (ectodermal cell differentiation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "The process in which relatively unspecialized cells acquire specialized structural and/or functional features of an ectodermal cell. Differentiation includes the processes involved in commitment of a cell to a specific fate.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010668") +AnnotationAssertion(rdfs:label "ectodermal cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (negative regulation of norepinephrine secretion) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that decreases the frequency, rate or extent of the regulated release of norepinephrine.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010700") +AnnotationAssertion(rdfs:label "negative regulation of norepinephrine secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of norepinephrine secretion) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that increases the frequency, rate or extent of the regulated release of norepinephrine.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010701") +AnnotationAssertion(rdfs:label "positive regulation of norepinephrine secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of collagen catabolic process) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the rate, frequency or extent of collagen catabolism. Collagen catabolism is the proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix.") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "regulation of collagen breakdown") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "regulation of collagen catabolism") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "regulation of collagen degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010710") +AnnotationAssertion(rdfs:label "regulation of collagen catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of collagen catabolic process) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that decreases the rate, frequency or extent of collagen catabolism. Collagen catabolism is the proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix.") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "down regulation of collagen catabolic process") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "down-regulation of collagen catabolic process") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "downregulation of collagen catabolic process") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "negative regulation of collagen breakdown") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "negative regulation of collagen catabolism") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "negative regulation of collagen degradation") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "inhibition of collagen catabolic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010711") +AnnotationAssertion(rdfs:label "negative regulation of collagen catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of collagen metabolic process) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals.") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "regulation of collagen metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010712") +AnnotationAssertion(rdfs:label "regulation of collagen metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of collagen metabolic process) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010713") +AnnotationAssertion(rdfs:label "negative regulation of collagen metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of collagen metabolic process) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals.") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "positive regulation of collagen metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010714") +AnnotationAssertion(rdfs:label "positive regulation of collagen metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of extracellular matrix disassembly) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix.") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "regulation of extracellular matrix breakdown") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "regulation of extracellular matrix degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010715") +AnnotationAssertion(rdfs:label "regulation of extracellular matrix disassembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of extracellular matrix disassembly) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that decreases the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix.") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "down regulation of extracellular matrix disassembly") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "down-regulation of extracellular matrix disassembly") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "downregulation of extracellular matrix disassembly") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "negative regulation of extracellular matrix breakdown") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "negative regulation of extracellular matrix degradation") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "inhibition of extracellular matrix disassembly") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010716") +AnnotationAssertion(rdfs:label "negative regulation of extracellular matrix disassembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of epithelial to mesenchymal transition) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010717") +AnnotationAssertion(rdfs:label "regulation of epithelial to mesenchymal transition") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of epithelial to mesenchymal transition) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that increases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition is where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010718") +AnnotationAssertion(rdfs:label "positive regulation of epithelial to mesenchymal transition") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (negative regulation of epithelial to mesenchymal transition) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that decreases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010719") +AnnotationAssertion(rdfs:label "negative regulation of epithelial to mesenchymal transition") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (positive regulation of cell development) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that increases the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010720") +AnnotationAssertion(rdfs:label "positive regulation of cell development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of cell development) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that decreases the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010721") +AnnotationAssertion(rdfs:label "negative regulation of cell development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of macrophage chemotaxis) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the rate, frequency or extent of macrophage chemotaxis. Macrophage chemotaxis is the movement of a macrophage in response to an external stimulus.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010758") +AnnotationAssertion(rdfs:label "regulation of macrophage chemotaxis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of macrophage chemotaxis) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that increases the rate, frequency or extent of macrophage chemotaxis. Macrophage chemotaxis is the movement of a macrophage in response to an external stimulus.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010759") +AnnotationAssertion(rdfs:label "positive regulation of macrophage chemotaxis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of macrophage chemotaxis) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that decreases the rate, frequency or extent of macrophage chemotaxis. Macrophage chemotaxis is the movement of a macrophage in response to an external stimulus.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010760") +AnnotationAssertion(rdfs:label "negative regulation of macrophage chemotaxis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (fibroblast migration) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:tb") "Cell migration that is accomplished by extension and retraction of a fibroblast pseudopodium. A fibroblast is a connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules.") +AnnotationAssertion(Annotation( "GOC:dph") "fibroblast cell migration") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010761") +AnnotationAssertion(rdfs:label "fibroblast migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of fibroblast migration) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium.") +AnnotationAssertion(Annotation( "GOC:dph") "regulation of fibroblast cell migration") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010762") +AnnotationAssertion(rdfs:label "regulation of fibroblast migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of fibroblast migration) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that increases the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium.") +AnnotationAssertion(Annotation( "GOC:dph") "positive regulation of fibroblast cell migration") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010763") +AnnotationAssertion(rdfs:label "positive regulation of fibroblast migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of fibroblast migration) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that decreases the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium.") +AnnotationAssertion(Annotation( "GOC:dph") "negative regulation of fibroblast cell migration") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010764") +AnnotationAssertion(rdfs:label "negative regulation of fibroblast migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of sodium ion transport) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that increases the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010765") +AnnotationAssertion(rdfs:label "positive regulation of sodium ion transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of sodium ion transport) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that decreases the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010766") +AnnotationAssertion(rdfs:label "negative regulation of sodium ion transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of cell morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that increases the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/24299"^^xsd:anyURI) +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010770") +AnnotationAssertion(rdfs:label "positive regulation of cell morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (negative regulation of cell morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that decreases the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/24299"^^xsd:anyURI) +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010771") +AnnotationAssertion(rdfs:label "negative regulation of cell morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (calcitonin catabolic process) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:rl") "The chemical reactions and pathways resulting in the breakdown of the peptide calcitonin.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010816") +AnnotationAssertion(rdfs:label "calcitonin catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + # Class: (regulation of hormone levels) AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the levels of hormone within an organism or a tissue. A hormone is any substance formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells in the same organism, upon which it has a specific regulatory action.") @@ -32279,6 +62259,127 @@ AnnotationAssertion( "GO:0010817") AnnotationAssertion(rdfs:label "regulation of hormone levels") +# Class: (T cell chemotaxis) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "The directed movement of a T cell in response to an external stimulus. A T cell is a type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex.") +AnnotationAssertion(Annotation( "CL:0000084") "T-cell chemotaxis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010818") +AnnotationAssertion(rdfs:label "T cell chemotaxis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of T cell chemotaxis) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the rate, frequency or extent of T cell chemotaxis. T cell chemotaxis is the directed movement of a T cell in response to an external stimulus.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010819") +AnnotationAssertion(rdfs:label "regulation of T cell chemotaxis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of T cell chemotaxis) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that increases the rate, frequency or extent of T cell chemotaxis. T cell chemotaxis is the directed movement of a T cell in response to an external stimulus.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010820") +AnnotationAssertion(rdfs:label "positive regulation of T cell chemotaxis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of glucose transmembrane transport) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the frequency, rate or extent of glucose transport across a membrane. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "regulation of glucose transport") +AnnotationAssertion( "GO:0010827") +AnnotationAssertion(rdfs:label "regulation of glucose transmembrane transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of glucose transmembrane transport) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that increases the frequency, rate or extent of glucose transport across a membrane. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "positive regulation of glucose transport") +AnnotationAssertion( "GO:0010828") +AnnotationAssertion(rdfs:label "positive regulation of glucose transmembrane transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of glucose transmembrane transport) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that decreases the frequency, rate or extent of glucose transport across a membrane. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "negative regulation of glucose transport") +AnnotationAssertion( "GO:0010829") +AnnotationAssertion(rdfs:label "negative regulation of glucose transmembrane transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of myotube differentiation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010830") +AnnotationAssertion(rdfs:label "regulation of myotube differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of myotube differentiation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that activates, maintains or increases the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010831") +AnnotationAssertion(rdfs:label "positive regulation of myotube differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of myotube differentiation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that decreases the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010832") +AnnotationAssertion(rdfs:label "negative regulation of myotube differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of keratinocyte proliferation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the rate, frequency or extent of keratinocyte proliferation. Keratinocyte proliferation is the multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010837") +AnnotationAssertion(rdfs:label "regulation of keratinocyte proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (positive regulation of keratinocyte proliferation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that increases the rate, frequency or extent of keratinocyte proliferation. Keratinocyte proliferation is the multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010838") +AnnotationAssertion(rdfs:label "positive regulation of keratinocyte proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of keratinocyte proliferation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that decreases the rate, frequency or extent of keratinocyte proliferation. Keratinocyte proliferation is the multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010839") +AnnotationAssertion(rdfs:label "negative regulation of keratinocyte proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (retina layer formation) + +AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") Annotation( "PMID:1270266") "The process in which the vertebrate retina is organized into three laminae: the outer nuclear layer (ONL), which contains photoreceptor nuclei; the inner nuclear layer (INL), which contains amacrine, bipolar and horizontal cells; and the retinal ganglion cell (RGC) layer. Between the inner and outer nuclear layers, the outer plexiform layer (OPL) contains connections between the photoreceptors and bipolar and horizontal cells. The inner plexiform layer (IPL) is positioned between the INL and the ganglion cell layer and contains the dendrites of RGCs and processes of bipolar and amacrine cells. Spanning all layers of the retina are the radially oriented Mueller glia.") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "retinal lamination") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "retinal layer formation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010842") +AnnotationAssertion(rdfs:label "retina layer formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (lipid localization) AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process in which a lipid is transported to, or maintained in, a specific location.") @@ -32286,8 +62387,282 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:0010876") AnnotationAssertion(rdfs:label "lipid localization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (positive regulation of steroid biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:tb") "Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010893") +AnnotationAssertion(rdfs:label "positive regulation of steroid biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of steroid biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:tb") "Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010894") +AnnotationAssertion(rdfs:label "negative regulation of steroid biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of glucose metabolic process) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:tb") "Any process that modulates the rate, frequency or extent of glucose metabolism. Glucose metabolic processes are the chemical reactions and pathways involving glucose, the aldohexose gluco-hexose.") +AnnotationAssertion(Annotation( "GOC:tb") "regulation of glucose metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010906") +AnnotationAssertion(rdfs:label "regulation of glucose metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (positive regulation of glucose metabolic process) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:tb") "Any process that increases the rate, frequency or extent of glucose metabolism. Glucose metabolic processes are the chemical reactions and pathways involving glucose, the aldohexose gluco-hexose.") +AnnotationAssertion(Annotation( "GOC:tb") "positive regulation of glucose metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010907") +AnnotationAssertion(rdfs:label "positive regulation of glucose metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (cellular component assembly involved in morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "The cellular component assembly that is part of the initial shaping of the component during its developmental progression.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010927") +AnnotationAssertion(rdfs:label "cellular component assembly involved in morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (macrophage cytokine production) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:rl") Annotation( "GOC:tb") "The appearance of a macrophage cytokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010934") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.") +AnnotationAssertion(rdfs:label "macrophage cytokine production") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of macrophage cytokine production) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:rl") "Any process that modulates the rate, frequency or extent of macrophage cytokine production. Macrophage cytokine production is the appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010935") +AnnotationAssertion(rdfs:label "regulation of macrophage cytokine production") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of macrophage cytokine production) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:rl") "Any process that decreases the rate, frequency or extent of macrophage cytokine production. Macrophage cytokine production is the appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010936") +AnnotationAssertion(rdfs:label "negative regulation of macrophage cytokine production") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of cytoplasmic microtubule depolymerization) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the frequency, rate or extent of cytoplasmic microtubule depolymerization.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010937") +AnnotationAssertion(rdfs:label "regulation of cytoplasmic microtubule depolymerization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (cytoplasmic microtubule depolymerization) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "The removal of tubulin heterodimers from one or both ends of a cytoplasmic microtubule.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010938") +AnnotationAssertion(rdfs:label "cytoplasmic microtubule depolymerization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (negative regulation of cell cycle process) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that decreases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2009-04-27T09:53:22Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010948") +AnnotationAssertion(rdfs:label "negative regulation of cell cycle process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (positive regulation of protein processing) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mah") Annotation( "GOC:tb") "Any process that increases the rate, frequency or extent of protein maturation by peptide bond cleavage.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2009-04-27T12:09:13Z") +AnnotationAssertion(Annotation( "GOC:bf") "positive regulation of protein maturation by peptide bond cleavage") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010954") +AnnotationAssertion(rdfs:label "positive regulation of protein processing") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (negative regulation of protein processing) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mah") Annotation( "GOC:tb") "Any process that decreases the rate, frequency or extent of protein maturation by peptide bond cleavage.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2009-04-27T12:10:19Z") +AnnotationAssertion(Annotation( "GOC:bf") "negative regulation of protein maturation by peptide bond cleavage") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010955") +AnnotationAssertion(rdfs:label "negative regulation of protein processing") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of amino acid import across plasma membrane) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the frequency, rate or extent of amino acid import into a cell.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2009-05-06T11:33:12Z") +AnnotationAssertion( "regulation of amino acid import") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010958") +AnnotationAssertion(rdfs:label "regulation of amino acid import across plasma membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of metal ion transport) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the frequency, rate, or extent of metal ion transport. Metal ion transport is the directed movement of metal ions, any metal ion with an electric charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2009-05-06T11:40:55Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010959") +AnnotationAssertion(rdfs:label "regulation of metal ion transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of glucan biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the rate, frequency, or extent of glucan biosynthesis. Glucan biosynthetic processes are the chemical reactions and pathways resulting in the formation of glucans, polysaccharides consisting only of glucose residues.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2009-05-11T12:17:53Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010962") +AnnotationAssertion(rdfs:label "regulation of glucan biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of phosphate transport) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the frequency, rate or extent of phosphate transport. Phosphate transport is the directed movement of phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2009-05-20T11:42:50Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010966") +AnnotationAssertion(rdfs:label "regulation of phosphate transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of microtubule nucleation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the rate, frequency or extent of microtubule nucleation. Microtubule nucleation is the 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2009-05-20T11:51:21Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010968") +AnnotationAssertion(rdfs:label "regulation of microtubule nucleation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (transport along microtubule) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mah") Annotation( "GOC:tb") "The movement of organelles or other particles from one location in the cell to another along microtubules, driven by motor activity.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2009-05-27T10:56:08Z") +AnnotationAssertion( "microtubule-based transport") +AnnotationAssertion(Annotation( "GOC:dph") "establishment of localization by movement along microtubule") +AnnotationAssertion( "movement along microtubule") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010970") +AnnotationAssertion(rdfs:label "transport along microtubule") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of neuron projection development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).") +AnnotationAssertion( "tb") +AnnotationAssertion( "2009-06-01T10:44:45Z") +AnnotationAssertion(Annotation( "GOC:mah") "regulation of neurite biosynthesis") +AnnotationAssertion(Annotation( "GOC:mah") "regulation of neurite development") +AnnotationAssertion(Annotation( "GOC:mah") "regulation of neurite formation") +AnnotationAssertion(Annotation( "GOC:mah") "regulation of neurite growth") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010975") +AnnotationAssertion(rdfs:label "regulation of neuron projection development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of neuron projection development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that increases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).") +AnnotationAssertion( "tb") +AnnotationAssertion( "2009-06-01T10:46:44Z") +AnnotationAssertion(Annotation( "GOC:mah") "positive regulation of neurite biosynthesis") +AnnotationAssertion(Annotation( "GOC:mah") "positive regulation of neurite development") +AnnotationAssertion(Annotation( "GOC:mah") "positive regulation of neurite formation") +AnnotationAssertion(Annotation( "GOC:mah") "positive regulation of neurite growth") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0010976") +AnnotationAssertion(rdfs:label "positive regulation of neuron projection development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of neuron projection development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that decreases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).") +AnnotationAssertion( "tb") +AnnotationAssertion( "2009-06-01T10:47:42Z") +AnnotationAssertion(Annotation( "GOC:mah") "negative regulation of neurite biosynthesis") +AnnotationAssertion(Annotation( "GOC:mah") "negative regulation of neurite development") +AnnotationAssertion(Annotation( "GOC:mah") "negative regulation of neurite formation") +AnnotationAssertion(Annotation( "GOC:mah") "negative regulation of neurite growth") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:pr") "growth cone collapse") +AnnotationAssertion( "GO:0010977") +AnnotationAssertion(rdfs:label "negative regulation of neuron projection development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (programmed cell death) + +AnnotationAssertion(Annotation( "GOC:lr") Annotation( "GOC:mtg_apoptosis") "A process which begins when a cell receives an internal or external signal and activates a series of biochemical events (signaling pathway). The process ends with the death of the cell.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/24835"^^xsd:anyURI) +AnnotationAssertion( "GO:0016244") +AnnotationAssertion( "regulated cell death") +AnnotationAssertion( "Wikipedia:Programmed_cell_death") +AnnotationAssertion( "caspase-independent cell death") +AnnotationAssertion( "non-apoptotic programmed cell death") +AnnotationAssertion( "nonapoptotic programmed cell death") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "PCD") +AnnotationAssertion( "RCD") +AnnotationAssertion( "caspase-independent apoptosis") +AnnotationAssertion( "GO:0012501") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:comment "Note that this term should be used to annotate gene products in the organism undergoing the programmed cell death. To annotate genes in another organism whose products modulate programmed cell death in a host organism, consider the term 'modulation by symbiont of host programmed cell death ; GO:0052040'. Also, note that 'programmed cell death ; GO:0012501' should be used to refer to instances of caspase-independent cell death mechanisms, in the absence of further indications on the process taking place. At present, caspase-independent cell death is not yet represented in GO due to the lack of consensus and in-depth research on the topic. 'programmed cell death ; GO:0012501' may also be used to annotate gene products in taxa where apoptosis as defined in GO:0006915 does not occur, such as plants. You may also consider these specific children: GO:0097468 'programmed cell death in response to reactive oxygen species' (with descendants GO:0010421 'hydrogen peroxide-mediated programmed cell death' and GO:0010343 'singlet oxygen-mediated programmed cell death'), and GO:0009626 'plant-type hypersensitive response' and its children.") +AnnotationAssertion(rdfs:label "programmed cell death") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + # Class: (endomembrane system) AnnotationAssertion(Annotation( "GOC:lh") "A collection of membranous structures involved in transport within the cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles.") @@ -32310,6 +62685,100 @@ AnnotationAssertion( "cellular_component") AnnotationAssertion( "GO:0012506") AnnotationAssertion(rdfs:label "vesicle membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (astrocyte development) + +AnnotationAssertion(Annotation( "GOC:dgh") Annotation( "GOC:ef") "The process aimed at the progression of an astrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. An astrocyte is the most abundant type of glial cell. Astrocytes provide support for neurons and regulate the environment in which they function.") +AnnotationAssertion( "astrocyte cell development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0014002") +AnnotationAssertion(rdfs:label "astrocyte development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (oligodendrocyte development) + +AnnotationAssertion(Annotation( "GOC:dgh") Annotation( "GOC:ef") "The process aimed at the progression of an oligodendrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. An oligodendrocyte is a type of glial cell involved in myelinating the axons in the central nervous system.") +AnnotationAssertion( "oligodendrocyte cell development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0014003") +AnnotationAssertion(rdfs:label "oligodendrocyte development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (glial cell proliferation) + +AnnotationAssertion(Annotation( "GOC:ef") Annotation( "ISBN:0878932585") "The multiplication or reproduction of glial cells by cell division, resulting in the expansion of their population. Glial cells exist throughout the nervous system, and include Schwann cells, astrocytes, and oligodendrocytes among others.") +AnnotationAssertion( "glia proliferation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0014009") +AnnotationAssertion(rdfs:label "glial cell proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (Schwann cell proliferation) + +AnnotationAssertion(Annotation( "GOC:ef") Annotation( "ISBN:0878932585") "The multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0014010") +AnnotationAssertion(rdfs:label "Schwann cell proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of gliogenesis) + +AnnotationAssertion(Annotation( "GOC:ef") "Any process that modulates the frequency, rate or extent of gliogenesis, the formation of mature glia.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0014013") +AnnotationAssertion(rdfs:label "regulation of gliogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of gliogenesis) + +AnnotationAssertion(Annotation( "GOC:ef") "Any process that stops, prevents, or reduces the frequency, rate or extent of gliogenesis, the formation of mature glia.") +AnnotationAssertion( "down regulation of gliogenesis") +AnnotationAssertion( "down-regulation of gliogenesis") +AnnotationAssertion( "downregulation of gliogenesis") +AnnotationAssertion( "inhibition of gliogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0014014") +AnnotationAssertion(rdfs:label "negative regulation of gliogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of gliogenesis) + +AnnotationAssertion(Annotation( "GOC:ef") "Any process that activates or increases the frequency, rate or extent of gliogenesis, the formation of mature glia.") +AnnotationAssertion( "up regulation of gliogenesis") +AnnotationAssertion( "up-regulation of gliogenesis") +AnnotationAssertion( "upregulation of gliogenesis") +AnnotationAssertion( "activation of gliogenesis") +AnnotationAssertion( "stimulation of gliogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0014015") +AnnotationAssertion(rdfs:label "positive regulation of gliogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (neuroblast differentiation) + +AnnotationAssertion(Annotation( "GOC:ef") Annotation( "ISBN:0878932585") "The process in which a relatively unspecialized cell acquires specialized features of a neuroblast. There are at least four stages through which the pluripotent cells of epiblast or blastula become neuroblasts.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0014016") +AnnotationAssertion(rdfs:label "neuroblast differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (neuroblast development) + +AnnotationAssertion(Annotation( "GOC:ef") Annotation( "ISBN:0878932585") "The process aimed at the progression of a neuroblast over time, from initial commitment of the cell to a specific state, to the mature neuroblast. It does not include processes where the neuroblast turns into a glial cell or a neuron.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0014019") +AnnotationAssertion(rdfs:label "neuroblast development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) # Class: (primary neural tube formation) @@ -32324,15 +62793,599 @@ AnnotationAssertion(rdfs:label "prim SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (neural rod formation) + +AnnotationAssertion(Annotation( "GOC:dh") Annotation( "GOC:ef") "The formation of a solid rod of neurectoderm derived from the neural keel. The neural rod is roughly circular in cross section. Neural rod formation occurs during primary neurulation in teleosts.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0014023") +AnnotationAssertion(rdfs:label "neural rod formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectAllValuesFrom( )) + +# Class: (neural keel formation) + +AnnotationAssertion(Annotation( "GOC:dh") Annotation( "GOC:ef") "The formation of a thickened region of the neurectoderm that is roughly triangular in cross section. The neural keel develops from the neural plate and develops into the neural rod. Neural keel formation occurs during primary neurulation in teleosts.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0014025") +AnnotationAssertion(rdfs:label "neural keel formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (notochord formation) + +AnnotationAssertion(Annotation( "GOC:dh") Annotation( "GOC:ef") "The formation of the notochord from the chordamesoderm. The notochord is composed of large cells packed within a firm connective tissue sheath and is found in all chordates at the ventral surface of the neural tube. In vertebrates, the notochord contributes to the vertebral column.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0014028") +AnnotationAssertion(rdfs:label "notochord formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (neural crest formation) + +AnnotationAssertion(Annotation( "GOC:dh") Annotation( "GOC:ef") "The formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation procedes.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0014029") +AnnotationAssertion(rdfs:label "neural crest formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (mesenchymal cell development) + +AnnotationAssertion(Annotation( "GOC:dh") Annotation( "GOC:ef") "The process aimed at the progression of a mesenchymal cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0014031") +AnnotationAssertion(rdfs:label "mesenchymal cell development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (neural crest cell development) + +AnnotationAssertion(Annotation( "GOC:dh") Annotation( "GOC:ef") "The process aimed at the progression of a neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0014032") +AnnotationAssertion(rdfs:label "neural crest cell development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (neural crest cell differentiation) + +AnnotationAssertion(Annotation( "GOC:dh") Annotation( "GOC:ef") "The process in which a relatively unspecialized cell acquires specialized features of a neural crest cell.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0014033") +AnnotationAssertion(rdfs:label "neural crest cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (Schwann cell differentiation) + +AnnotationAssertion(Annotation( "GOC:ef") "The process in which a relatively unspecialized cell acquires the specialized features of a Schwann cell. Schwann cells are found in the peripheral nervous system, where they insulate neurons and axons, and regulate the environment in which neurons function.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0014037") +AnnotationAssertion(rdfs:label "Schwann cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (regulation of Schwann cell differentiation) + +AnnotationAssertion(Annotation( "GOC:ef") "Any process that modulates the frequency, rate or extent of Schwann cell differentiation.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0014038") +AnnotationAssertion(rdfs:label "regulation of Schwann cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of Schwann cell differentiation) + +AnnotationAssertion(Annotation( "GOC:ef") "Any process that stops, prevents, or reduces the frequency, rate or extent of Schwann cell differentiation.") +AnnotationAssertion( "down regulation of Schwann cell differentiation") +AnnotationAssertion( "down-regulation of Schwann cell differentiation") +AnnotationAssertion( "downregulation of Schwann cell differentiation") +AnnotationAssertion( "inhibition of Schwann cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0014039") +AnnotationAssertion(rdfs:label "negative regulation of Schwann cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of Schwann cell differentiation) + +AnnotationAssertion(Annotation( "GOC:ef") "Any process that activates or increases the frequency, rate or extent of Schwann cell differentiation.") +AnnotationAssertion( "up regulation of Schwann cell differentiation") +AnnotationAssertion( "up-regulation of Schwann cell differentiation") +AnnotationAssertion( "upregulation of Schwann cell differentiation") +AnnotationAssertion( "activation of Schwann cell differentiation") +AnnotationAssertion( "stimulation of Schwann cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0014040") +AnnotationAssertion(rdfs:label "positive regulation of Schwann cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of neuron maturation) + +AnnotationAssertion(Annotation( "GOC:ef") "Any process that modulates the frequency, rate or extent of neuron maturation, the process leading to the attainment of the full functional capacity of a neuron. This process is independent of morphogenetic change.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0014041") +AnnotationAssertion(rdfs:label "regulation of neuron maturation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (positive regulation of neuron maturation) + +AnnotationAssertion(Annotation( "GOC:ef") "Any process that activates or increases the frequency, rate or extent of neuron maturation.") +AnnotationAssertion( "up regulation of neuron maturation") +AnnotationAssertion( "up-regulation of neuron maturation") +AnnotationAssertion( "upregulation of neuron maturation") +AnnotationAssertion( "activation of neuron maturation") +AnnotationAssertion( "stimulation of neuron maturation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0014042") +AnnotationAssertion(rdfs:label "positive regulation of neuron maturation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of neuron maturation) + +AnnotationAssertion(Annotation( "GOC:ef") "Any process that stops, prevents, or reduces the frequency, rate or extent of neuron maturation.") +AnnotationAssertion( "down regulation of neuron maturation") +AnnotationAssertion( "down-regulation of neuron maturation") +AnnotationAssertion( "downregulation of neuron maturation") +AnnotationAssertion( "inhibition of neuron maturation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0014043") +AnnotationAssertion(rdfs:label "negative regulation of neuron maturation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (Schwann cell development) + +AnnotationAssertion(Annotation( "GOC:dgh") Annotation( "GOC:ef") "The process aimed at the progression of a Schwann cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. Schwann cells are found in the peripheral nervous system, where they insulate neurons and axons, and regulate the environment in which neurons function.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0014044") +AnnotationAssertion(rdfs:label "Schwann cell development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (dopamine secretion) + +AnnotationAssertion(Annotation( "GOC:ef") "The regulated release of dopamine by a cell. Dopamine is a catecholamine and a precursor of adrenaline and noradrenaline. It acts as a neurotransmitter in the central nervous system but it is also produced peripherally and acts as a hormone.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0014046") +AnnotationAssertion(rdfs:label "dopamine secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + # Class: (glutamate secretion) AnnotationAssertion(Annotation( "GOC:ef") "The controlled release of glutamate by a cell. The glutamate is the most abundant excitatory neurotransmitter in the nervous system.") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0014047") AnnotationAssertion(rdfs:label "glutamate secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) +# Class: (regulation of glutamate secretion) + +AnnotationAssertion(Annotation( "GOC:ef") "Any process that modulates the frequency, rate or extent of the controlled release of glutamate.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0014048") +AnnotationAssertion(rdfs:label "regulation of glutamate secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of glutamate secretion) + +AnnotationAssertion(Annotation( "GOC:ef") "Any process that activates or increases the frequency, rate or extent of the controlled release of glutamate.") +AnnotationAssertion( "up regulation of glutamate secretion") +AnnotationAssertion( "up-regulation of glutamate secretion") +AnnotationAssertion( "upregulation of glutamate secretion") +AnnotationAssertion( "activation of glutamate secretion") +AnnotationAssertion( "stimulation of glutamate secretion") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0014049") +AnnotationAssertion(rdfs:label "positive regulation of glutamate secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of glutamate secretion) + +AnnotationAssertion(Annotation( "GOC:ef") "Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of glutamate.") +AnnotationAssertion( "down regulation of glutamate secretion") +AnnotationAssertion( "down-regulation of glutamate secretion") +AnnotationAssertion( "downregulation of glutamate secretion") +AnnotationAssertion( "inhibition of glutamate secretion") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0014050") +AnnotationAssertion(rdfs:label "negative regulation of glutamate secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (gamma-aminobutyric acid secretion) + +AnnotationAssertion(Annotation( "GOC:ef") "The regulated release of gamma-aminobutyric acid by a cell or a tissue. The gamma-aminobutyric acid is the principal inhibitory neurotransmitter in the brain but is also found in several extraneural tissues.") +AnnotationAssertion( "GABA secretion") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0014051") +AnnotationAssertion(rdfs:label "gamma-aminobutyric acid secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of gamma-aminobutyric acid secretion) + +AnnotationAssertion(Annotation( "GOC:ef") "Any process that modulates the frequency, rate or extent of the regulated release of gamma-aminobutyric acid.") +AnnotationAssertion( "regulation of GABA secretion") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0014052") +AnnotationAssertion(rdfs:label "regulation of gamma-aminobutyric acid secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of gamma-aminobutyric acid secretion) + +AnnotationAssertion(Annotation( "GOC:ef") "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of gamma-aminobutyric acid.") +AnnotationAssertion( "down regulation of gamma-aminobutyric acid secretion") +AnnotationAssertion( "down-regulation of gamma-aminobutyric acid secretion") +AnnotationAssertion( "downregulation of gamma-aminobutyric acid secretion") +AnnotationAssertion( "negative regulation of GABA secretion") +AnnotationAssertion( "inhibition of gamma-aminobutyric acid secretion") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0014053") +AnnotationAssertion(rdfs:label "negative regulation of gamma-aminobutyric acid secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of gamma-aminobutyric acid secretion) + +AnnotationAssertion(Annotation( "GOC:ef") "Any process that activates or increases the frequency, rate or extent of the regulated release of gamma-aminobutyric acid.") +AnnotationAssertion( "positive regulation of GABA secretion") +AnnotationAssertion( "up regulation of gamma-aminobutyric acid secretion") +AnnotationAssertion( "up-regulation of gamma-aminobutyric acid secretion") +AnnotationAssertion( "upregulation of gamma-aminobutyric acid secretion") +AnnotationAssertion( "activation of gamma-aminobutyric acid secretion") +AnnotationAssertion( "stimulation of gamma-aminobutyric acid secretion") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0014054") +AnnotationAssertion(rdfs:label "positive regulation of gamma-aminobutyric acid secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (acetylcholine secretion, neurotransmission) + +AnnotationAssertion(Annotation( "GOC:ef") "The regulated release of acetylcholine by a cell. The acetylcholine acts as a neurotransmitter that acts in both the peripheral nervous system (PNS) and central nervous system (CNS).") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0014055") +AnnotationAssertion(rdfs:label "acetylcholine secretion, neurotransmission") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of acetylcholine secretion, neurotransmission) + +AnnotationAssertion(Annotation( "GOC:ef") "Any process that modulates the frequency, rate or extent of the regulated release of acetylcholine.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0014056") +AnnotationAssertion(rdfs:label "regulation of acetylcholine secretion, neurotransmission") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (positive regulation of acetylcholine secretion, neurotransmission) + +AnnotationAssertion(Annotation( "GOC:ef") "Any process that activates or increases the frequency, rate or extent of the regulated release of acetylcholine.") +AnnotationAssertion( "up regulation of acetylcholine secretion") +AnnotationAssertion( "up-regulation of acetylcholine secretion") +AnnotationAssertion( "upregulation of acetylcholine secretion") +AnnotationAssertion( "activation of acetylcholine secretion") +AnnotationAssertion( "stimulation of acetylcholine secretion") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0014057") +AnnotationAssertion(rdfs:label "positive regulation of acetylcholine secretion, neurotransmission") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (negative regulation of acetylcholine secretion, neurotransmission) + +AnnotationAssertion(Annotation( "GOC:ef") "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of acetylcholine.") +AnnotationAssertion( "down regulation of acetylcholine secretion") +AnnotationAssertion( "down-regulation of acetylcholine secretion") +AnnotationAssertion( "downregulation of acetylcholine secretion") +AnnotationAssertion( "inhibition of acetylcholine secretion") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0014058") +AnnotationAssertion(rdfs:label "negative regulation of acetylcholine secretion, neurotransmission") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (regulation of dopamine secretion) + +AnnotationAssertion(Annotation( "GOC:ef") "Any process that modulates the frequency, rate or extent of the regulated release of dopamine.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0014059") +AnnotationAssertion(rdfs:label "regulation of dopamine secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of epinephrine secretion) + +AnnotationAssertion(Annotation( "GOC:ef") "Any process that modulates the frequency, rate or extent of the regulated release of epinephrine.") +AnnotationAssertion( "regulation of adrenaline secretion") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0014060") +AnnotationAssertion(rdfs:label "regulation of epinephrine secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of norepinephrine secretion) + +AnnotationAssertion(Annotation( "GOC:ef") "Any process that modulates the frequency, rate or extent of the regulated release of norepinephrine.") +AnnotationAssertion( "regulation of noradrenaline secretion") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0014061") +AnnotationAssertion(rdfs:label "regulation of norepinephrine secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of serotonin secretion) + +AnnotationAssertion(Annotation( "GOC:ef") "Any process that modulates the frequency, rate or extent of the regulated release of serotonin.") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:tb") "regulation of serotonin release") +AnnotationAssertion( "GO:0014062") +AnnotationAssertion(rdfs:label "regulation of serotonin secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of serotonin secretion) + +AnnotationAssertion(Annotation( "GOC:ef") "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of serotonin.") +AnnotationAssertion( "down regulation of serotonin secretion") +AnnotationAssertion( "down-regulation of serotonin secretion") +AnnotationAssertion( "downregulation of serotonin secretion") +AnnotationAssertion( "inhibition of serotonin secretion") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:tb") "positive regulation of serotonin release") +AnnotationAssertion( "GO:0014063") +AnnotationAssertion(rdfs:label "negative regulation of serotonin secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of serotonin secretion) + +AnnotationAssertion(Annotation( "GOC:ef") "Any process that activates or increases the frequency, rate or extent of the regulated release of serotonin.") +AnnotationAssertion( "up regulation of serotonin secretion") +AnnotationAssertion( "up-regulation of serotonin secretion") +AnnotationAssertion( "upregulation of serotonin secretion") +AnnotationAssertion( "activation of serotonin secretion") +AnnotationAssertion( "stimulation of serotonin secretion") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:tb") "positive regulation of serotonin release") +AnnotationAssertion( "GO:0014064") +AnnotationAssertion(rdfs:label "positive regulation of serotonin secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (response to organic cyclic compound) + +AnnotationAssertion(Annotation( "GOC:ef") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus.") +AnnotationAssertion(Annotation( "GOC:mah") "response to organic cyclic substance") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0014070") +AnnotationAssertion(rdfs:label "response to organic cyclic compound") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (response to purine-containing compound) + +AnnotationAssertion(Annotation( "GOC:ef") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a purine-containing compound stimulus.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "response to purine") +AnnotationAssertion( "GO:0014074") +AnnotationAssertion(rdfs:label "response to purine-containing compound") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (response to amine) + +AnnotationAssertion(Annotation( "GOC:ef") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amine stimulus. An amine is a compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups.") +AnnotationAssertion(Annotation( "GOC:dos") "response to amine stimulus") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0014075") +AnnotationAssertion(rdfs:label "response to amine") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (striated muscle tissue development) + +AnnotationAssertion(Annotation( "CL:0000737") Annotation( "GOC:dph") Annotation( "GOC:mtg_muscle") "The process whose specific outcome is the progression of a striated muscle over time, from its formation to the mature structure. Striated muscle contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle. Skeletal muscle myoblasts fuse to form myotubes and eventually multinucleated muscle fibers. The fusion of cardiac cells is very rare and can only form binucleate cells.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0014706") +AnnotationAssertion(rdfs:label "striated muscle tissue development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (branchiomeric skeletal muscle development) + +AnnotationAssertion(Annotation( "GOC:mtg_muscle") "The process whose specific outcome is the progression of the branchiomeric skeletal muscle over time, from its formation to the mature structure. The branchiomeric muscle is derived from cranial mesoderm and controls facial expression, pharyngeal and laryngeal function, operating the jaw. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle. Branchiomeric muscles of mammals correspond to the gill musculature of fish.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0014707") +AnnotationAssertion(rdfs:label "branchiomeric skeletal muscle development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of somitomeric trunk muscle development) + +AnnotationAssertion(Annotation( "GOC:mtg_muscle") "Any process that modulates the frequency, rate or extent of somitomeric trunk muscle development.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0014708") +AnnotationAssertion(rdfs:label "regulation of somitomeric trunk muscle development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of somitomeric trunk muscle development) + +AnnotationAssertion(Annotation( "GOC:mtg_muscle") "Any process that activates, maintains or increases the frequency, rate or extent of somitomeric trunk muscle development. The somitomeric trunk muscle is derived from somitomeric mesoderm. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0014709") +AnnotationAssertion(rdfs:label "positive regulation of somitomeric trunk muscle development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of somitomeric trunk muscle development) + +AnnotationAssertion(Annotation( "GOC:mtg_muscle") "Any process that stops, prevents, or reduces the frequency, rate or extent of somitomeric trunk muscle development. The somitomeric trunk muscle is derived from somitomeric mesoderm. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0014710") +AnnotationAssertion(rdfs:label "negative regulation of somitomeric trunk muscle development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of branchiomeric skeletal muscle development) + +AnnotationAssertion(Annotation( "GOC:mtg_muscle") "Any process that modulates the frequency, rate or extent of branchiomeric skeletal muscle development. Branchiomeric skeletal muscle development is the process whose specific outcome is the progression of the branchiomeric skeletal muscle over time, from its formation to the mature structure.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0014711") +AnnotationAssertion(rdfs:label "regulation of branchiomeric skeletal muscle development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of branchiomeric skeletal muscle development) + +AnnotationAssertion(Annotation( "GOC:mtg_muscle") "Any process that activates, maintains or increases the frequency, rate or extent of branchiomeric skeletal muscle development. Branchiomeric skeletal muscle development is the process whose specific outcome is the progression of the branchiomeric skeletal muscle over time, from its formation to the mature structure.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0014712") +AnnotationAssertion(rdfs:label "positive regulation of branchiomeric skeletal muscle development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of branchiomeric skeletal muscle development) + +AnnotationAssertion(Annotation( "GOC:mtg_muscle") "Any process that stops, prevents, or reduces the frequency, rate or extent of branchiomeric skeletal muscle development. Branchiomeric skeletal muscle development is the process whose specific outcome is the progression of the branchiomeric skeletal muscle over time, from its formation to the mature structure.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0014713") +AnnotationAssertion(rdfs:label "negative regulation of branchiomeric skeletal muscle development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of extraocular skeletal muscle development) + +AnnotationAssertion(Annotation( "GOC:mtg_muscle") "Any process that modulates the frequency, rate or extent of extraocular skeletal muscle development. Extraocular skeletal muscle development is the process whose specific outcome is the progression of the extraocular skeletal muscle over time, from its formation to the mature structure. The extraocular muscle is derived from cranial mesoderm and controls eye movements. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0014725") +AnnotationAssertion(rdfs:label "regulation of extraocular skeletal muscle development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of extraocular skeletal muscle development) + +AnnotationAssertion(Annotation( "GOC:mtg_muscle") "Any process that stops, prevents, or reduces the frequency, rate or extent of extraocular skeletal muscle development. Extraocular skeletal muscle development is the process whose specific outcome is the progression of the extraocular skeletal muscle over time, from its formation to the mature structure. The extraocular muscle is derived from cranial mesoderm and controls eye movements. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0014726") +AnnotationAssertion(rdfs:label "negative regulation of extraocular skeletal muscle development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of extraocular skeletal muscle development) + +AnnotationAssertion(Annotation( "GOC:mtg_muscle") "Any process that activates, maintains or increases the frequency, rate or extent of extraocular skeletal muscle development. Extraocular skeletal muscle development is the process whose specific outcome is the progression of the extraocular skeletal muscle over time, from its formation to the mature structure. The extraocular muscle is derived from cranial mesoderm and controls eye movements. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0014727") +AnnotationAssertion(rdfs:label "positive regulation of extraocular skeletal muscle development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of skeletal muscle adaptation) + +AnnotationAssertion(Annotation( "GOC:mtg_muscle") "Any process in which skeletal muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "regulation of skeletal muscle plasticity") +AnnotationAssertion( "GO:0014733") +AnnotationAssertion(rdfs:label "regulation of skeletal muscle adaptation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (skeletal muscle hypertrophy) + +AnnotationAssertion(Annotation( "GOC:mtg_muscle") "The enlargement or overgrowth of all or part of an organ due to an increase in size (not length) of individual muscle fibers without cell division. In the case of skeletal muscle cells this happens due to the additional synthesis of sarcomeric proteins and assembly of myofibrils.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0014734") +AnnotationAssertion(rdfs:label "skeletal muscle hypertrophy") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of muscle hypertrophy) + +AnnotationAssertion(Annotation( "GOC:mtg_muscle") "Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle hypertrophy.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0014741") +AnnotationAssertion(rdfs:label "negative regulation of muscle hypertrophy") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of muscle hypertrophy) + +AnnotationAssertion(Annotation( "GOC:mtg_muscle") "Any process that activates or increases the frequency, rate or extent of muscle hypertrophy.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0014742") +AnnotationAssertion(rdfs:label "positive regulation of muscle hypertrophy") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of muscle hypertrophy) + +AnnotationAssertion(Annotation( "GOC:mtg_muscle") "Any process that modulates the frequency, rate or extent of muscle hypertrophy.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0014743") +AnnotationAssertion(rdfs:label "regulation of muscle hypertrophy") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of muscle adaptation) + +AnnotationAssertion(Annotation( "GOC:mtg_muscle") "Any process that activates or increases the frequency, rate or extent of muscle adaptation.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "positive regulation of muscle plasticity") +AnnotationAssertion( "GO:0014744") +AnnotationAssertion(rdfs:label "positive regulation of muscle adaptation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (negative regulation of muscle adaptation) + +AnnotationAssertion(Annotation( "GOC:mtg_muscle") "Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle adaptation.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "negative regulation of muscle plasticity") +AnnotationAssertion( "GO:0014745") +AnnotationAssertion(rdfs:label "negative regulation of muscle adaptation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (smooth muscle adaptation) + +AnnotationAssertion(Annotation( "GOC:mtg_muscle") "Any process in which smooth muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "smooth muscle plasticity") +AnnotationAssertion( "GO:0014805") +AnnotationAssertion(rdfs:label "smooth muscle adaptation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of somitogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_muscle") "Any process that modulates the frequency, rate or extent of somitogenesis.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0014807") +AnnotationAssertion(rdfs:label "regulation of somitogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (muscle cell migration) + +AnnotationAssertion(Annotation( "CL:0000187") Annotation( "GOC:mtg_muscle") "The orderly movement of a muscle cell from one site to another, often during the development of a multicellular organism.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0014812") +AnnotationAssertion(rdfs:label "muscle cell migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of skeletal muscle contraction) + +AnnotationAssertion(Annotation( "GOC:ef") Annotation( "GOC:mtg_muscle") "Any process that modulates the frequency, rate or extent of skeletal muscle contraction.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0014819") +AnnotationAssertion(rdfs:label "regulation of skeletal muscle contraction") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (phasic smooth muscle contraction) AnnotationAssertion(Annotation( "GOC:mtg_muscle") "A process in which force is generated within phasic smooth muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. In the phasic smooth muscle, the muscle contraction occurs without an ordered sarcomeric structure. Phasic smooth muscle contraction occurs in a series of discrete contractions and relaxations.") @@ -32341,6 +63394,309 @@ AnnotationAssertion( "phasic smooth muscle contraction") SubClassOf( ) +# Class: (intestine smooth muscle contraction) + +AnnotationAssertion(Annotation( "GOC:mtg_muscle") Annotation( "MA:0001539") Annotation( "MSH:D007422") "A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the intestine. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The intestine is the section of the alimentary canal from the stomach to the anal canal. It includes the large intestine and small intestine.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0014827") +AnnotationAssertion(rdfs:label "intestine smooth muscle contraction") +SubClassOf( ) +SubClassOf( ) + +# Class: (gastro-intestinal system smooth muscle contraction) + +AnnotationAssertion(Annotation( "GOC:mtg_muscle") Annotation( "MA:0001523") Annotation( "MSH:D041981") "A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the gastro-intestinal system. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The gastro-intestinal system generally refers to the digestive structures stretching from the mouth to anus, but does not include the accessory glandular organs (liver, pancreas and biliary tract).") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0014831") +AnnotationAssertion(rdfs:label "gastro-intestinal system smooth muscle contraction") +SubClassOf( ) + +# Class: (urinary bladder smooth muscle contraction) + +AnnotationAssertion(Annotation( "GOC:mr") Annotation( "GOC:mtg_muscle") Annotation( "PMID:11768524") Annotation( "PMID:18276178") Annotation( "PMID:538956") "A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the urinary bladder. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The urinary bladder is a musculomembranous sac along the urinary tract.") +AnnotationAssertion( ) +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0014832") +AnnotationAssertion(rdfs:label "urinary bladder smooth muscle contraction") +SubClassOf( ) +SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses( ObjectSomeValuesFrom( )) + +# Class: (myoblast differentiation involved in skeletal muscle regeneration) + +AnnotationAssertion(Annotation( "CL:0000056") Annotation( "GOC:ef") Annotation( "GOC:mtg_muscle") Annotation( "PMID:16607119") "The process in which a relatively unspecialized satellite cell acquires specialized features of a myoblast. This occurs as part of skeletal muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0014835") +AnnotationAssertion(rdfs:label "myoblast differentiation involved in skeletal muscle regeneration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (myoblast migration involved in skeletal muscle regeneration) + +AnnotationAssertion(Annotation( "CL:0000056") Annotation( "GOC:ef") Annotation( "GOC:mtg_muscle") Annotation( "PMID:16607119") "The process in which a myoblast migrates along an entire fiber to the site of injury. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.") +AnnotationAssertion( "mononucleate cell migration involved in skeletal muscle regeneration") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0014839") +AnnotationAssertion(rdfs:label "myoblast migration involved in skeletal muscle regeneration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (urinary tract smooth muscle contraction) + +AnnotationAssertion(Annotation( "GOC:ef") Annotation( "GOC:mtg_muscle") Annotation( "MA:0000325") Annotation( "MSH:D014551") "A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the urinary tract. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The urinary tract consists of organs of the body that produce and discharge urine. These include the kidneys, ureters, bladder, and urethra.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0014848") +AnnotationAssertion(rdfs:label "urinary tract smooth muscle contraction") +SubClassOf( ) + +# Class: (ureter smooth muscle contraction) + +AnnotationAssertion(Annotation( "GOC:mtg_muscle") Annotation( "MA:0000378") "A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the ureter. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The ureter is one of a pair of thick-walled tubes that transports urine from the kidney pelvis to the urinary bladder.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0014849") +AnnotationAssertion(rdfs:label "ureter smooth muscle contraction") +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of skeletal muscle contraction by neural stimulation via neuromuscular junction) + +AnnotationAssertion(Annotation( "GOC:ef") Annotation( "GOC:mtg_muscle") "Any process that modulates the frequency, rate or extent of skeletal muscle contraction by variation of the pattern of stimulation by nervous system.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0014852") +AnnotationAssertion(rdfs:label "regulation of skeletal muscle contraction by neural stimulation via neuromuscular junction") +SubClassOf( ) + +# Class: (regulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction) + +AnnotationAssertion(Annotation( "GOC:ef") Annotation( "GOC:mtg_muscle") "Any process, involved in skeletal muscle contraction, that modulates the establishment or extent of the excitatory postsynaptic potential (EPSP). Excitatory postsynaptic potential (EPSP) is a temporay increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential.") +AnnotationAssertion( "regulation of excitatory post-synaptic membrane potential involved in skeletal muscle contraction") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0014853") +AnnotationAssertion(rdfs:label "regulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (striated muscle cell proliferation) + +AnnotationAssertion(Annotation( "CL:0000737") Annotation( "GOC:ef") Annotation( "GOC:mtg_muscle") "The multiplication or reproduction of striated muscle cells, resulting in the expansion of a cell population. Striated muscles contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0014855") +AnnotationAssertion(rdfs:label "striated muscle cell proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (skeletal muscle cell proliferation) + +AnnotationAssertion(Annotation( "CL:0000188") Annotation( "GOC:ef") Annotation( "GOC:mtg_muscle") "The multiplication or reproduction of skeletal muscle cells, resulting in the expansion of a cell population.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0014856") +AnnotationAssertion(rdfs:label "skeletal muscle cell proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of skeletal muscle cell proliferation) + +AnnotationAssertion(Annotation( "CL:0000188") Annotation( "GOC:ef") Annotation( "GOC:mtg_muscle") "Any process that modulates the frequency, rate or extent of skeletal muscle cell proliferation.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0014857") +AnnotationAssertion(rdfs:label "regulation of skeletal muscle cell proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of skeletal muscle cell proliferation) + +AnnotationAssertion(Annotation( "CL:0000188") Annotation( "GOC:ef") Annotation( "GOC:mtg_muscle") "Any process that activates or increases the frequency, rate or extent of skeletal muscle cell proliferation.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0014858") +AnnotationAssertion(rdfs:label "positive regulation of skeletal muscle cell proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of skeletal muscle cell proliferation) + +AnnotationAssertion(Annotation( "CL:0000188") Annotation( "GOC:ef") Annotation( "GOC:mtg_muscle") "Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle cell proliferation.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0014859") +AnnotationAssertion(rdfs:label "negative regulation of skeletal muscle cell proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (neurotransmitter secretion involved in regulation of skeletal muscle contraction) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_muscle") Annotation( "GOC:tb") "The regulated release of neurotransmitter into the synaptic cleft involved in skeletal muscle contraction. A neurotransmitter is any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell. Among the many substances that have the properties of a neurotransmitter are acetylcholine, noradrenaline, adrenaline, dopamine, glycine, gamma aminobutyrate, glutamic acid, substance P, enkephalins, endorphins and serotonin.") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "neurotransmitter secretion involved in control of skeletal muscle contraction") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0014860") +AnnotationAssertion(rdfs:label "neurotransmitter secretion involved in regulation of skeletal muscle contraction") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (regulation of skeletal muscle contraction via regulation of action potential) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mtg_cardiac_conduct_nov11") Annotation( "GOC:mtg_muscle") "Any process that modulates the frequency, rate or extent of skeletal muscle contraction by depolarization of muscle membrane and ionic fluxes.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "regulation of skeletal muscle contraction via membrane action potential") +AnnotationAssertion( "GO:0014861") +AnnotationAssertion(rdfs:label "regulation of skeletal muscle contraction via regulation of action potential") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (skeletal myofibril assembly) + +AnnotationAssertion(Annotation( "GOC:ef") Annotation( "GOC:mtg_muscle") "The process whose specific outcome is the progression of the skeletal myofibril over time, from its formation to the mature structure. A skeletal myofibril is a myofibril specific to skeletal muscle cells.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0014866") +AnnotationAssertion(rdfs:label "skeletal myofibril assembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (myoblast division) + +AnnotationAssertion(Annotation( "CL:0000056") Annotation( "GOC:ef") Annotation( "GOC:mtg_muscle") "The process resulting in the physical partitioning and separation of a myoblast into daughter cells. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0014872") +AnnotationAssertion(rdfs:label "myoblast division") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (response to stimulus involved in regulation of muscle adaptation) + +AnnotationAssertion(Annotation( "GOC:ef") Annotation( "GOC:mtg_muscle") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. This occurs as part of the regulation of muscle adaptation.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "response to stimulus involved in regulation of muscle plasticity") +AnnotationAssertion( "GO:0014874") +AnnotationAssertion(rdfs:label "response to stimulus involved in regulation of muscle adaptation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (response to electrical stimulus involved in regulation of muscle adaptation) + +AnnotationAssertion(Annotation( "GOC:ef") Annotation( "GOC:mtg_muscle") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electrical stimulus. This process occurs as part of the regulation of muscle adaptation.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "response to electrical stimulus involved in regulation of muscle plasticity") +AnnotationAssertion( "GO:0014878") +AnnotationAssertion(rdfs:label "response to electrical stimulus involved in regulation of muscle adaptation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (detection of electrical stimulus involved in regulation of muscle adaptation) + +AnnotationAssertion(Annotation( "GOC:ef") Annotation( "GOC:mtg_muscle") "The series of events by which an electrical stimulus is received and converted into a molecular signal. This occurs as part of the regulation of muscle adaptation.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0014879") +AnnotationAssertion(rdfs:label "detection of electrical stimulus involved in regulation of muscle adaptation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (cardiac muscle adaptation) + +AnnotationAssertion(Annotation( "GOC:mtg_muscle") "The process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "cardiac muscle plasticity") +AnnotationAssertion( "GO:0014887") +AnnotationAssertion(rdfs:label "cardiac muscle adaptation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (striated muscle adaptation) + +AnnotationAssertion(Annotation( "GOC:mtg_muscle") "Any process in which striated muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "striated muscle plasticity") +AnnotationAssertion( "GO:0014888") +AnnotationAssertion(rdfs:label "striated muscle adaptation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (smooth muscle hypertrophy) + +AnnotationAssertion(Annotation( "GOC:mtg_muscle") "The enlargement or overgrowth of all or part of an organ due to an increase in size of its smooth muscle cells without cell division. Physiological hypertrophy is a normal process during development, and can also occur in mature structures on demand. In the uterus, smooth muscle cells undergo hypertrophy during pregnancy.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0014895") +AnnotationAssertion(rdfs:label "smooth muscle hypertrophy") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (muscle hypertrophy) + +AnnotationAssertion(Annotation( "GOC:mtg_muscle") "The muscle system process that results in enlargement or overgrowth of all or part of a muscle organ due to an increase in the size of its muscle cells. Physiological hypertrophy is a normal process during development (it stops in cardiac muscle after adolescence) and can also be brought on in response to demand. In athletes cardiac and skeletal muscles undergo hypertrophy stimulated by increasing muscle activity on exercise. Smooth muscle cells in the uterus undergo hypertrophy during pregnancy.") +AnnotationAssertion( "Wikipedia:Muscle_hypertrophy") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0014896") +AnnotationAssertion(rdfs:label "muscle hypertrophy") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (striated muscle hypertrophy) + +AnnotationAssertion(Annotation( "GOC:mtg_muscle") "The enlargement or overgrowth of all or part of an organ due to an increase in size of muscle cells without cell division. In the case of striated muscle, this happens due to the additional synthesis of sarcomeric proteins and assembly of myofibrils.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0014897") +AnnotationAssertion(rdfs:label "striated muscle hypertrophy") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (myotube differentiation) + +AnnotationAssertion(Annotation( "GOC:mtg_muscle") "The process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotube differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual myotubes can fuse to form bigger myotubes and start to contract. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0014902") +AnnotationAssertion(rdfs:label "myotube differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (myotube cell development) + +AnnotationAssertion(Annotation( "GOC:mtg_muscle") "The process aimed at the progression of a myotube cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0014904") +AnnotationAssertion(rdfs:label "myotube cell development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (myotube cell development involved in skeletal muscle regeneration) + +AnnotationAssertion(Annotation( "GOC:mtg_muscle") "The process aimed at the progression of a myotube cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. This occurs as part of the process of skeletal muscle regeneration. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0014906") +AnnotationAssertion(rdfs:label "myotube cell development involved in skeletal muscle regeneration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (myotube differentiation involved in skeletal muscle regeneration) + +AnnotationAssertion(Annotation( "GOC:mtg_muscle") "The process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotube differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual myotubes can fuse to form bigger myotubes and start to contract. This process occurs as part of the process of skeletal muscle regeneration. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0014908") +AnnotationAssertion(rdfs:label "myotube differentiation involved in skeletal muscle regeneration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (smooth muscle cell migration) + +AnnotationAssertion(Annotation( "CL:0000192") Annotation( "GOC:mtg_muscle") "The orderly movement of a smooth muscle cell from one site to another, often during the development of a multicellular organism.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0014909") +AnnotationAssertion(rdfs:label "smooth muscle cell migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of smooth muscle cell migration) + +AnnotationAssertion(Annotation( "CL:0000192") Annotation( "GOC:mtg_muscle") "Any process that modulates the frequency, rate or extent of smooth muscle cell migration.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0014910") +AnnotationAssertion(rdfs:label "regulation of smooth muscle cell migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of smooth muscle cell migration) + +AnnotationAssertion(Annotation( "CL:0000192") Annotation( "GOC:mtg_muscle") "Any process that activates, maintains or increases the frequency, rate or extent of smooth muscle cell migration.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0014911") +AnnotationAssertion(rdfs:label "positive regulation of smooth muscle cell migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of smooth muscle cell migration) + +AnnotationAssertion(Annotation( "CL:0000192") Annotation( "GOC:mtg_muscle") "Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle cell migration.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0014912") +AnnotationAssertion(rdfs:label "negative regulation of smooth muscle cell migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (protein transport) AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") @@ -32352,10 +63708,77 @@ AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "protein transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ) +# Class: (monoatomic ion transmembrane transporter activity) + +AnnotationAssertion(Annotation( "GOC:dgf") Annotation( "GOC:mtg_transport") Annotation( "ISBN:0815340729") "Enables the transfer of an ion from one side of a membrane to the other.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/24479"^^xsd:anyURI) +AnnotationAssertion( "ion transmembrane transporter activity") +AnnotationAssertion( "ion transporter activity") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0015075") +AnnotationAssertion(rdfs:label "monoatomic ion transmembrane transporter activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "GO_REF:0000090") ObjectSomeValuesFrom( )) + +# Class: (sodium ion transmembrane transporter activity) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:ai") Annotation( "RHEA:34963") "Enables the transfer of sodium ions (Na+) from one side of a membrane to the other.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/24076"^^xsd:anyURI) +AnnotationAssertion( "GO:0022816") +AnnotationAssertion( "RHEA:34963") +AnnotationAssertion( "sodium transporter activity") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0015081") +AnnotationAssertion(rdfs:label "sodium ion transmembrane transporter activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (calcium ion transmembrane transporter activity) + +AnnotationAssertion(Annotation( "GOC:dgf") Annotation( "RHEA:29671") "Enables the transfer of calcium (Ca) ions from one side of a membrane to the other.") +AnnotationAssertion( "RHEA:29671") +AnnotationAssertion(Annotation(rdfs:label "CatSper Channel Mediated Calcium Transport") "Reactome:R-HSA-2534359") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0015085") +AnnotationAssertion(rdfs:label "calcium ion transmembrane transporter activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (organic cation transmembrane transporter activity) + +AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:mtg_transport") Annotation( "ISBN:0815340729") "Enables the transfer of organic cations from one side of a membrane to the other. Organic cations are atoms or small molecules with a positive charge that contain carbon in covalent linkage.") +AnnotationAssertion(Annotation(rdfs:label "abacavir [extracellular] => abacavir [cytosol]") "Reactome:R-HSA-2161500") +AnnotationAssertion(Annotation(rdfs:label "OCT1 transports organic cations into hepatic cells") "Reactome:R-HSA-549129") +AnnotationAssertion(Annotation(rdfs:label "OCT2 mediates tubular uptake of organic cations in the kidney") "Reactome:R-HSA-549279") +AnnotationAssertion(Annotation(rdfs:label "OCT3 mediates renal clearance of organic cations") "Reactome:R-HSA-549304") +AnnotationAssertion(Annotation(rdfs:label "OCT1 transports organic cations out of hepatic cells") "Reactome:R-HSA-549322") +AnnotationAssertion(Annotation(rdfs:label "OCT2 mediates tubular secretion of organic cations in the kidney") "Reactome:R-HSA-561054") +AnnotationAssertion(Annotation(rdfs:label "OCT3 mediates renal uptake of organic cations") "Reactome:R-HSA-561072") +AnnotationAssertion(Annotation(rdfs:label "SLCO1A2 transports Cipro(1+) into the cytosol") "Reactome:R-HSA-9794270") +AnnotationAssertion(Annotation(rdfs:label "SLC22A1 transports Cipro into renal cell") "Reactome:R-HSA-9794523") +AnnotationAssertion(Annotation(rdfs:label "SLC22A1 transports Cipro into hepatic cell") "Reactome:R-HSA-9795207") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0015101") +AnnotationAssertion(rdfs:label "organic cation transmembrane transporter activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (inorganic anion transmembrane transporter activity) + +AnnotationAssertion(Annotation( "GOC:ai") "Enables the transfer of inorganic anions from one side of a membrane to the other. Inorganic anions are atoms or small molecules with a negative charge which do not contain carbon in covalent linkage.") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0015103") +AnnotationAssertion(rdfs:label "inorganic anion transmembrane transporter activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (bicarbonate transmembrane transporter activity) AnnotationAssertion(Annotation( "GOC:ai") "Enables the transfer of bicarbonate from one side of a membrane to the other. Bicarbonate is the hydrogencarbonate ion, HCO3-.") @@ -32364,9 +63787,384 @@ AnnotationAssertion(Annotation(rdfs:label "BESTs transport cytosolic HCO3- to ex AnnotationAssertion( "molecular_function") AnnotationAssertion( "GO:0015106") AnnotationAssertion(rdfs:label "bicarbonate transmembrane transporter activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (phosphate ion transmembrane transporter activity) + +AnnotationAssertion(Annotation( "GOC:ai") "Enables the transfer of phosphate (PO4 3-) ions from one side of a membrane to the other.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2012-11-22T15:43:10Z") +AnnotationAssertion( "GO:1901677") +AnnotationAssertion( "RHEA:32823") +AnnotationAssertion( "molecular_function") +AnnotationAssertion(Annotation( "GOC:vw") "phosphate transmembrane transporter activity") +AnnotationAssertion( "GO:0015114") +AnnotationAssertion(rdfs:label "phosphate ion transmembrane transporter activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "GO_REF:0000090") ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (sulfate transmembrane transporter activity) + +AnnotationAssertion(Annotation( "GOC:ai") "Enables the transfer of sulfate ions, SO4(2-), from one side of a membrane to the other.") +AnnotationAssertion( "RHEA:34983") +AnnotationAssertion(Annotation(rdfs:label "Defective SLC26A2 does not cotransport extracellular SO4(2-), H+ to cytosol") "Reactome:R-HSA-3560789") +AnnotationAssertion(Annotation(rdfs:label "SLC26A1,2 cotransport SO4(2-), H+ from extracellular region to cytosol") "Reactome:R-HSA-427555") +AnnotationAssertion(Annotation(rdfs:label "SLC26A11 transports SO4(2-) from extracellular region to cytosol") "Reactome:R-HSA-8875871") +AnnotationAssertion( "sulphate transporter activity") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "sulfate permease activity") +AnnotationAssertion( "GO:0015116") +AnnotationAssertion(rdfs:label "sulfate transmembrane transporter activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "GO_REF:0000090") ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (acetate transmembrane transporter activity) + +AnnotationAssertion(Annotation( "GOC:ai") "Enables the transfer of acetate from one side of a membrane to the other. Acetate is the 2-carbon carboxylic acid ethanoic acid.") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0015123") +AnnotationAssertion(rdfs:label "acetate transmembrane transporter activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "GO_REF:0000090") ObjectSomeValuesFrom( )) + +# Class: (bile acid transmembrane transporter activity) + +AnnotationAssertion(Annotation( "GOC:ai") "Enables the transfer of bile acid from one side of a membrane to the other. Bile acids are any of a group of steroid carboxylic acids occurring in bile, where they are present as the sodium salts of their amides with glycine or taurine.") +AnnotationAssertion(Annotation(rdfs:label "SLCO1B3 transports ALB:(GCCA, TCCA) from extracellular region to cytosol") "Reactome:R-HSA-194079") +AnnotationAssertion(Annotation(rdfs:label "SLCO1B1 transports ALB:(GCCA,TCCA) from extracellular region to cytosol") "Reactome:R-HSA-194083") +AnnotationAssertion(Annotation(rdfs:label "Transport (influx) of bile salts and acids by OATP-A") "Reactome:R-HSA-194130") +AnnotationAssertion(Annotation(rdfs:label "Defective SLCO1B1 does not transport BIL from extracellular region (blood) to cytosol (hepatocyte)") "Reactome:R-HSA-5661184") +AnnotationAssertion(Annotation(rdfs:label "Defective SLCO1B3 does not transport BIL from extracellular region (blood) to cytosol (hepatocyte)") "Reactome:R-HSA-5661198") +AnnotationAssertion(Annotation(rdfs:label "SLC51A:SLC51B transports bile salts from cytosol to extracellular region") "Reactome:R-HSA-9733964") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0015125") +AnnotationAssertion(rdfs:label "bile acid transmembrane transporter activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (bilirubin transmembrane transporter activity) + +AnnotationAssertion(Annotation( "GOC:ai") Annotation( "ISBN:0198547684") "Enables the transfer of bilirubin from one side of a membrane to the other. Bilirubin is a linear tetrapyrrole produced in the reticuloendothelial system from biliverdin and transported to the liver as a complex with serum albumin. In the liver, bilirubin is converted to bilirubin bisglucuronide, which is excreted in the bile.") +AnnotationAssertion(Annotation(rdfs:label "Defective ABCC2 does not transport BMG,BDG from cytosol to extracellular region") "Reactome:R-HSA-5679031") +AnnotationAssertion(Annotation(rdfs:label "ABCC2 transports BMG,BDG from cytosol to extracellular region") "Reactome:R-HSA-5679041") +AnnotationAssertion(Annotation(rdfs:label "ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region") "Reactome:R-HSA-9661417") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0015127") +AnnotationAssertion(rdfs:label "bilirubin transmembrane transporter activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (carbohydrate transmembrane transporter activity) + +AnnotationAssertion(Annotation( "GOC:jl") Annotation( "GOC:mtg_transport") Annotation( "ISBN:0815340729") "Enables the transfer of carbohydrate from one side of a membrane to the other.") +AnnotationAssertion( "GO:1901476") +AnnotationAssertion( "sugar transporter") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "carbohydrate transporter activity") +AnnotationAssertion( "GO:0015144") +AnnotationAssertion(rdfs:label "carbohydrate transmembrane transporter activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "GO_REF:0000090") ObjectSomeValuesFrom( )) + +# Class: (monosaccharide transmembrane transporter activity) + +AnnotationAssertion(Annotation( "GOC:jl") Annotation( "GOC:mtg_transport") Annotation( "ISBN:0815340729") "Enables the transfer of a monosaccharide from one side of a membrane to the other.") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0015145") +AnnotationAssertion(rdfs:label "monosaccharide transmembrane transporter activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (pentose transmembrane transporter activity) + +AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:mtg_transport") Annotation( "ISBN:0815340729") "Enables the transfer of a pentose sugar from one side of a membrane to the other. Pentose is a monosaccharide with 5 carbon atoms.") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0015146") +AnnotationAssertion(rdfs:label "pentose transmembrane transporter activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (hexose transmembrane transporter activity) + +AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:mtg_transport") Annotation( "ISBN:0815340729") "Enables the transfer of a hexose sugar, a monosaccharide with 6 carbon atoms, from one side of a membrane to the other.") +AnnotationAssertion(Annotation(rdfs:label "SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region") "Reactome:R-HSA-189242") +AnnotationAssertion(Annotation(rdfs:label "Defective SLC2A2 does not transport Fru, Gal, Glc from cytosol to extracellular region") "Reactome:R-HSA-5638222") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0015149") +AnnotationAssertion(rdfs:label "hexose transmembrane transporter activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "GO_REF:0000090") ObjectSomeValuesFrom( )) + +# Class: (polysaccharide transmembrane transporter activity) + +AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:mtg_transport") Annotation( "ISBN:0815340729") "Enables the transfer of polysaccharides from one side of a membrane to the other. A polysaccharide is a polymer of many (typically more than 10) monosaccharide residues linked glycosidically.") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0015159") +AnnotationAssertion(rdfs:label "polysaccharide transmembrane transporter activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (amino acid transmembrane transporter activity) + +AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:mtg_transport") Annotation( "ISBN:0815340729") "Enables the transfer of amino acids from one side of a membrane to the other. Amino acids are organic molecules that contain an amino group and a carboxyl group.") +AnnotationAssertion( "GO:0015359") +AnnotationAssertion( "amino acid transporter activity") +AnnotationAssertion(Annotation(rdfs:label "glutamate uptake by astrocytes") "Reactome:R-HSA-210439") +AnnotationAssertion(Annotation(rdfs:label "L-Glutamine transport into neurons") "Reactome:R-HSA-212642") +AnnotationAssertion(Annotation(rdfs:label "SLC6A18 transports Gly from extracellular region to cytosol") "Reactome:R-HSA-351963") +AnnotationAssertion(Annotation(rdfs:label "SLC6A6-mediated uptake of taurine and beta-alanine") "Reactome:R-HSA-351987") +AnnotationAssertion(Annotation(rdfs:label "SLC6A12 (BGT-1)-mediated uptake of GABA and betaine") "Reactome:R-HSA-352029") +AnnotationAssertion(Annotation(rdfs:label "SLC6A20 cotransports L-Pro, Na+ from the extracellular region to cytosol") "Reactome:R-HSA-352052") +AnnotationAssertion(Annotation(rdfs:label "SLC6A15-mediated amino acid uptake") "Reactome:R-HSA-352059") +AnnotationAssertion(Annotation(rdfs:label "SLC43A1 (LAT3)-mediated uptake of large neutral amino acids") "Reactome:R-HSA-352103") +AnnotationAssertion(Annotation(rdfs:label "SLC43A2 (LAT4)-mediated uptake of large neutral amino acids") "Reactome:R-HSA-352107") +AnnotationAssertion(Annotation(rdfs:label "SLC38A2 (ATA2)-mediated uptake of neutral amino acids") "Reactome:R-HSA-352108") +AnnotationAssertion(Annotation(rdfs:label "SLC38A1 (ATA1)-mediated uptake of neutral amino acids") "Reactome:R-HSA-352119") +AnnotationAssertion(Annotation(rdfs:label "SLC38A4 (ATA3)-mediated uptake of arginine and lysine") "Reactome:R-HSA-352136") +AnnotationAssertion(Annotation(rdfs:label "SLC16A10-mediated uptake of aromatic amino acids") "Reactome:R-HSA-352158") +AnnotationAssertion(Annotation(rdfs:label "SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine") "Reactome:R-HSA-352174") +AnnotationAssertion(Annotation(rdfs:label "SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine") "Reactome:R-HSA-352182") +AnnotationAssertion(Annotation(rdfs:label "SLC7A8-mediated uptake of neutral amino acids") "Reactome:R-HSA-352191") +AnnotationAssertion(Annotation(rdfs:label "SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol") "Reactome:R-HSA-352232") +AnnotationAssertion(Annotation(rdfs:label "SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine") "Reactome:R-HSA-352347") +AnnotationAssertion(Annotation(rdfs:label "SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine") "Reactome:R-HSA-352354") +AnnotationAssertion(Annotation(rdfs:label "SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine") "Reactome:R-HSA-352364") +AnnotationAssertion(Annotation(rdfs:label "SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine") "Reactome:R-HSA-352371") +AnnotationAssertion(Annotation(rdfs:label "SLC1A5-mediated exchange of alanine and glutamine across the plasma membrane") "Reactome:R-HSA-352379") +AnnotationAssertion(Annotation(rdfs:label "SLC1A5-mediated exchange of glutamine and alanine across the plasma membrane") "Reactome:R-HSA-352385") +AnnotationAssertion(Annotation(rdfs:label "SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol") "Reactome:R-HSA-375405") +AnnotationAssertion(Annotation(rdfs:label "SLC36A1-mediated uptake of glycine, proline, and alanine") "Reactome:R-HSA-375417") +AnnotationAssertion(Annotation(rdfs:label "SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol") "Reactome:R-HSA-375473") +AnnotationAssertion(Annotation(rdfs:label "SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol") "Reactome:R-HSA-375487") +AnnotationAssertion(Annotation(rdfs:label "SLC7A2, isoform B (CAT-2B)-mediated uptake of cationic amino acids") "Reactome:R-HSA-375768") +AnnotationAssertion(Annotation(rdfs:label "SLC7A3 (CAT-3)-mediated uptake of cationic amino acids") "Reactome:R-HSA-375770") +AnnotationAssertion(Annotation(rdfs:label "SLC7A1 (CAT-1)-mediated uptake of cationic amino acids") "Reactome:R-HSA-375776") +AnnotationAssertion(Annotation(rdfs:label "SLC7A2, isoform A (CAT-2A)-mediated uptake of cationic amino acids") "Reactome:R-HSA-375790") +AnnotationAssertion(Annotation(rdfs:label "SLC7A10-mediated uptake of small neutral amino acids") "Reactome:R-HSA-376200") +AnnotationAssertion(Annotation(rdfs:label "SLC7A11-mediated exchange of extracellular cysteine and cytosolic glutamate") "Reactome:R-HSA-378513") +AnnotationAssertion(Annotation(rdfs:label "SLC7A7:SLC3A2 exchanges L-Arg for L-Leu, Na+ across the plasma membrane") "Reactome:R-HSA-379415") +AnnotationAssertion(Annotation(rdfs:label "SLC7A6 (y+LAT2)-mediated exchange of extracellular leucine for cytosolic arginine") "Reactome:R-HSA-379426") +AnnotationAssertion(Annotation(rdfs:label "SLC7A9:SLC3A1 exchanges L-Arg, CySS-, L-Lys for L-Leu") "Reactome:R-HSA-379432") +AnnotationAssertion(Annotation(rdfs:label "Defective SLC36A2 does not cotransport Gly, L-Pro with H+ from extracellular region to cytosol") "Reactome:R-HSA-5653850") +AnnotationAssertion(Annotation(rdfs:label "Defective SLC3A1 (in SLC7A9:SLC3A1) does not exchange L-Arg, CySS-, L-Lys for L-Leu") "Reactome:R-HSA-5655702") +AnnotationAssertion(Annotation(rdfs:label "Variant SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol") "Reactome:R-HSA-5659674") +AnnotationAssertion(Annotation(rdfs:label "Defective SLC6A19 does not cotransport neutral amino acids, Na+ from extracellular region to cytosol") "Reactome:R-HSA-5659734") +AnnotationAssertion(Annotation(rdfs:label "Defective SLC6A18 does not transport Gly from extracellular region to cytosol") "Reactome:R-HSA-5659755") +AnnotationAssertion(Annotation(rdfs:label "Variant SLC6A20 does not cotransport L-Pro, Na+ from extracellulare region to cytosol") "Reactome:R-HSA-5660694") +AnnotationAssertion(Annotation(rdfs:label "Defective SLC7A9 (in SLC7A9:SLC3A1) does not exchange L-Arg, CySS-, L-Lys for L-Leu") "Reactome:R-HSA-5660890") +AnnotationAssertion(Annotation(rdfs:label "Defective SLC7A7 does not exchange L-Arg for L-Leu, Na+ across the plasma membrane") "Reactome:R-HSA-5660910") +AnnotationAssertion(Annotation(rdfs:label "Loading of GABA into clathrin sculpted GABA transport vesicle lumen") "Reactome:R-HSA-888592") +AnnotationAssertion(Annotation(rdfs:label "SLC38A9 transports L-Arg from lysosomal lumen to cytosol") "Reactome:R-HSA-8952726") +AnnotationAssertion( "amino acid permease activity") +AnnotationAssertion( "amino acid/choline transmembrane transporter activity") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "general amino acid permease activity") +AnnotationAssertion( "hydroxy/aromatic amino acid permease activity") +AnnotationAssertion( "GO:0015171") +AnnotationAssertion(rdfs:label "amino acid transmembrane transporter activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "GO_REF:0000090") ObjectSomeValuesFrom( )) + +# Class: (acidic amino acid transmembrane transporter activity) + +AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:mtg_transport") Annotation( "ISBN:0815340729") "Enables the transfer of acidic amino acids from one side of a membrane to the other. Acidic amino acids have side chains with a negative charge at pH 7.3.") +AnnotationAssertion( "acidic amino acid transporter activity") +AnnotationAssertion(Annotation(rdfs:label "SLC25A12,13 exchange cytosolic L-Glu for mitochondrial matrix L-Asp") "Reactome:R-HSA-372448") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0015172") +AnnotationAssertion(rdfs:label "acidic amino acid transmembrane transporter activity") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (L-amino acid transmembrane transporter activity) + +AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:jsg") Annotation( "GOC:mah") Annotation( "GOC:mtg_transport") Annotation( "ISBN:0815340729") "Enables the transfer of an L-amino acid from one side of a membrane to the other. L-amino acids are the L-enantiomers of amino acids.") +AnnotationAssertion( "L-amino acid transporter activity") +AnnotationAssertion(Annotation(rdfs:label "Glutamine transport from astrocytes") "Reactome:R-HSA-212614") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0015179") +AnnotationAssertion(rdfs:label "L-amino acid transmembrane transporter activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf(Annotation( "GO_REF:0000090") ObjectSomeValuesFrom( )) + +# Class: (gamma-aminobutyric acid transmembrane transporter activity) + +AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "GOC:mtg_transport") Annotation( "ISBN:0198506732") Annotation( "ISBN:0815340729") "Enables the transfer of gamma-aminobutyric acid from one side of a membrane to the other. Gamma-aminobutyric acid is 4-aminobutyrate (GABA).") +AnnotationAssertion( "4-aminobutanoate transporter activity") +AnnotationAssertion( "4-aminobutyrate transporter activity") +AnnotationAssertion( "GABA transporter activity") +AnnotationAssertion( "betaine/GABA:sodium symporter activity") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0015185") +AnnotationAssertion(rdfs:label "gamma-aminobutyric acid transmembrane transporter activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (nucleobase transmembrane transporter activity) + +AnnotationAssertion(Annotation( "ISBN:0198506732") "Enables the transfer of a nucleobase, any nitrogenous base that is a constituent of a nucleoside, nucleotide, or nucleic acidfrom one side of a membrane to the other.") +AnnotationAssertion( "GO:0015392") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0015205") +AnnotationAssertion(rdfs:label "nucleobase transmembrane transporter activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (adenine transmembrane transporter activity) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Enables the transfer of adenine, 6-aminopurine, from one side of a membrane to the other.") +AnnotationAssertion( "RHEA:34999") +AnnotationAssertion(Annotation(rdfs:label "SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane") "Reactome:R-HSA-163215") +AnnotationAssertion(Annotation(rdfs:label "ARL2:GTP:ARL2BP:SLC25A4 dimer exchanges ATP for ADP across the mitochondrial inner membrane") "Reactome:R-HSA-5672027") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0015207") +AnnotationAssertion(rdfs:label "adenine transmembrane transporter activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (purine nucleoside transmembrane transporter activity) + +AnnotationAssertion(Annotation( "GOC:ai") "Enables the transfer of a purine nucleoside, a purine base covalently bonded to a ribose or deoxyribose sugar, from one side of a membrane to the other.") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0015211") +AnnotationAssertion(rdfs:label "purine nucleoside transmembrane transporter activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "GO_REF:0000090") ObjectSomeValuesFrom( )) + +# Class: (nucleotide transmembrane transporter activity) + +AnnotationAssertion(Annotation( "ISBN:0198506732") "Enables the transfer of a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate, from one side of a membrane to the other.") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0015215") +AnnotationAssertion(rdfs:label "nucleotide transmembrane transporter activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf(Annotation( "GO_REF:0000090") ObjectSomeValuesFrom( )) + +# Class: (purine nucleotide transmembrane transporter activity) + +AnnotationAssertion(Annotation( "GOC:ai") "Enables the transfer of a purine nucleotide, any compound consisting of a purine nucleoside esterified with (ortho)phosphate, from one side of a membrane to the other.") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0015216") +AnnotationAssertion(rdfs:label "purine nucleotide transmembrane transporter activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (ADP transmembrane transporter activity) + +AnnotationAssertion(Annotation( "GOC:ai") "Enables the transfer of ADP, adenosine diphosphate, from one side of a membrane to the other.") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0015217") +AnnotationAssertion(rdfs:label "ADP transmembrane transporter activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (choline transmembrane transporter activity) + +AnnotationAssertion(Annotation( "GOC:ai") "Enables the transfer of choline from one side of a membrane to the other. Choline (2-hydroxyethyltrimethylammonium) is an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine.") +AnnotationAssertion( "GO:0005306") +AnnotationAssertion(Annotation(rdfs:label "SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol") "Reactome:R-HSA-429594") +AnnotationAssertion(Annotation(rdfs:label "Cho transports from the extracellular space to the cytosol") "Reactome:R-HSA-444433") +AnnotationAssertion(Annotation(rdfs:label "Defective SLC5A7 does not cotransport Cho, Cl-, Na+ from extracellular region to cytosol") "Reactome:R-HSA-5658483") +AnnotationAssertion(Annotation(rdfs:label "SLC44A1 transports Cho from cytosol to mitochondrial matrix") "Reactome:R-HSA-6797956") +AnnotationAssertion( "choline permease activity") +AnnotationAssertion( "amino acid/choline transmembrane transporter activity") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0015220") +AnnotationAssertion(rdfs:label "choline transmembrane transporter activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (fatty acid transmembrane transporter activity) + +AnnotationAssertion(Annotation( "ISBN:0198506732") "Enables the transfer of fatty acids from one side of a membrane to the other. Fatty acids are aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis.") +AnnotationAssertion( "GO:0015246") +AnnotationAssertion( "fatty-acyl group transporter activity") +AnnotationAssertion(Annotation(rdfs:label "Defective SLC27A4 does not transport LCFAs from extracellular region to cytosol") "Reactome:R-HSA-5627891") +AnnotationAssertion(Annotation(rdfs:label "SLC27A1,4,6 transport LCFAs from extracellular region to cytosol") "Reactome:R-HSA-879585") +AnnotationAssertion( "fatty acyl transporter activity") +AnnotationAssertion( "peroxisomal fatty acyl transporter") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "fatty acid transporter activity") +AnnotationAssertion( "GO:0015245") +AnnotationAssertion(rdfs:label "fatty acid transmembrane transporter activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (inorganic molecular entity transmembrane transporter activity) + +AnnotationAssertion(Annotation( "GOC:mtg_transport") Annotation( "ISBN:0815340729") "Enables the transfer of an inorganic molecular entity from the outside of a cell to the inside of the cell across a membrane. An inorganic molecular entity is a molecular entity that contains no carbon.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/14372"^^xsd:anyURI) +AnnotationAssertion( "inorganic solute uptake transmembrane transporter activity") +AnnotationAssertion( "inorganic uptake permease activity") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0015318") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "inorganic molecular entity transmembrane transporter activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (acetylcholine receptor activity) + +AnnotationAssertion(Annotation( "GOC:jl") Annotation( "GOC:signaling") "Combining with an acetylcholine receptor ligand and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0015464") +AnnotationAssertion(rdfs:comment "For nicotinic acetylcholine receptors that act as ion channels, instead use 'acetylcholine-gated cation channel activity ; GO:0022848'.") +AnnotationAssertion(rdfs:label "acetylcholine receptor activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (formate transmembrane transporter activity) + +AnnotationAssertion(Annotation( "GOC:ai") "Enables the transfer of formate from one side of a membrane to the other. Formate is also known as methanoate, the anion HCOO- derived from methanoic (formic) acid.") +AnnotationAssertion( "GO:0015659") +AnnotationAssertion( "RHEA:29679") +AnnotationAssertion( "formate uptake permease activity") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "formate uptake transmembrane transporter activity") +AnnotationAssertion( "GO:0015499") +AnnotationAssertion(rdfs:label "formate transmembrane transporter activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (alkane transmembrane transporter activity) + +AnnotationAssertion(Annotation( "GOC:ai") "Enables the transfer of alkanes from one side of a membrane to the other. Alkanes are saturated aliphatic hydrocarbon compounds.") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0015567") +AnnotationAssertion(rdfs:label "alkane transmembrane transporter activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "GO_REF:0000090") ObjectSomeValuesFrom( )) + +# Class: (D-ribose transmembrane transporter activity) + +AnnotationAssertion(Annotation( "GOC:mtg_transport") Annotation( "ISBN:0198506732") Annotation( "ISBN:0815340729") "Enables the transfer of D-ribose from one side of a membrane to the other. As beta-D-ribofuranose, D-ribose forms the glycose group of all ribonucleosides, ribonucleotides and ribonucleic acids, and also of ribose phosphates, various glycosides, some coenzymes and some forms of vitamin B12.") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0015591") +AnnotationAssertion(rdfs:label "D-ribose transmembrane transporter activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (organophosphate ester transmembrane transporter activity) + +AnnotationAssertion(Annotation( "GOC:mcc") "Enables the transfer of organophosphate esters from one side of a membrane to the other. Organophosphate esters are small organic molecules containing phosphate ester bonds.") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0015605") +AnnotationAssertion(rdfs:label "organophosphate ester transmembrane transporter activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (actin cytoskeleton) AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0395825172") Annotation( "ISBN:0815316194") "The part of the cytoskeleton (the internal framework of a cell) composed of actin and associated proteins. Includes actin cytoskeleton-associated complexes.") @@ -32375,12 +64173,124 @@ AnnotationAssertion( "actin cytoskeleton") SubClassOf( ) +# Class: (microtubule cytoskeleton) + +AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0395825172") "The part of the cytoskeleton (the internal framework of a cell) composed of microtubules and associated proteins.") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0015630") +AnnotationAssertion(rdfs:label "microtubule cytoskeleton") +SubClassOf( ) + +# Class: (tubulin binding) + +AnnotationAssertion(Annotation( "GOC:clt") "Binding to monomeric or multimeric forms of tubulin, including microtubules.") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0015631") +AnnotationAssertion(rdfs:label "tubulin binding") +SubClassOf( ) + +# Class: (short-chain fatty acid transmembrane transporter activity) + +AnnotationAssertion(Annotation( "GOC:mah") "Enables the transfer of short-chain fatty acids from one side of a membrane to the other. A short-chain fatty acid is a fatty acid with an aliphatic tail of less than 6 carbons.") +AnnotationAssertion( "GO:0015635") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "short-chain fatty acid transporter activity") +AnnotationAssertion( "short-chain fatty acid uptake transporter activity") +AnnotationAssertion( "GO:0015636") +AnnotationAssertion(rdfs:label "short-chain fatty acid transmembrane transporter activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (quaternary ammonium group transmembrane transporter activity) + +AnnotationAssertion(Annotation( "ISBN:0198506732") "Enables the transfer of quaternary ammonium groups from one side of a membrane to the other. Quaternary ammonium groups are any compound that can be regarded as derived from ammonium hydroxide or an ammonium salt by replacement of all four hydrogen atoms of the NH4+ ion by organic groups.") +AnnotationAssertion( "GO:0015202") +AnnotationAssertion( "quaternary amine transmembrane transporter activity") +AnnotationAssertion( "quaternary ammonium compound transporter activity") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0015651") +AnnotationAssertion(rdfs:label "quaternary ammonium group transmembrane transporter activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (alcohol transmembrane transporter activity) + +AnnotationAssertion(Annotation( "ISBN:0198506732") "Enables the transfer of an alcohol from one side of a membrane to the other. An alcohol is any carbon compound that contains a hydroxyl group.") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0015665") +AnnotationAssertion(rdfs:label "alcohol transmembrane transporter activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (gas transport) + +AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of substances that are gaseous in normal living conditions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0015669") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "gas transport") +SubClassOf( ) + +# Class: (carbon dioxide transport) + +AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of carbon dioxide (CO2) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0015670") +AnnotationAssertion(rdfs:label "carbon dioxide transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (oxygen transport) + +AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of oxygen (O2) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0015671") +AnnotationAssertion(rdfs:label "oxygen transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (organic cation transport) + +AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of organic cations into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organic cations are atoms or small molecules with a positive charge which contain carbon in covalent linkage.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0015695") +AnnotationAssertion(rdfs:label "organic cation transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (quaternary ammonium group transport) + +AnnotationAssertion(Annotation( "GOC:ai") Annotation( "ISBN:0198506732") "The directed movement into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore of quaternary ammonium compounds, any compound that can be regarded as derived from ammonium hydroxide or an ammonium salt by replacement of all four hydrogen atoms of the NH4+ ion by organic groups.") +AnnotationAssertion( "GO:0015845") +AnnotationAssertion( "quaternary amine transport") +AnnotationAssertion( "quaternary ammonium compound transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0015697") +AnnotationAssertion(rdfs:label "quaternary ammonium group transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (inorganic anion transport) + +AnnotationAssertion(Annotation( "GOC:krc") "The directed movement of inorganic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Inorganic anions are atoms or small molecules with a negative charge which do not contain carbon in covalent linkage.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0015698") +AnnotationAssertion(rdfs:label "inorganic anion transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (bicarbonate transport) AnnotationAssertion(Annotation( "GOC:krc") "The directed movement of bicarbonate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0015701") AnnotationAssertion(rdfs:label "bicarbonate transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (organic anion transport) + +AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:krc") "The directed movement of organic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organic anions are atoms or small molecules with a negative charge which contain carbon in covalent linkage.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0015711") +AnnotationAssertion(rdfs:label "organic anion transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (monocarboxylic acid transport) @@ -32388,6 +64298,7 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:0015718") AnnotationAssertion(rdfs:label "monocarboxylic acid transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) # Class: (bile acid and bile salt transport) @@ -32398,10 +64309,74 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0015721") AnnotationAssertion(rdfs:label "bile acid and bile salt transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ) +# Class: (bilirubin transport) + +AnnotationAssertion(Annotation( "GOC:krc") "The directed movement of bilirubin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0015723") +AnnotationAssertion(rdfs:label "bilirubin transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (formate transport) + +AnnotationAssertion(Annotation( "GOC:krc") "The directed movement of formate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0015724") +AnnotationAssertion(rdfs:label "formate transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (organophosphate ester transport) + +AnnotationAssertion(Annotation( "GOC:mcc") "The directed movement of organophosphate esters into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organophosphate esters are small organic molecules containing phosphate ester bonds.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0015748") +AnnotationAssertion(rdfs:label "organophosphate ester transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (monosaccharide transmembrane transport) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:vw") Annotation( "GO_REF:0000069") "The process in which a monosaccharide is transported across a lipid bilayer, from one side of a membrane to the other. Monosaccharides are the simplest carbohydrates; they are polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides.") +AnnotationAssertion( "vw") +AnnotationAssertion( "2017-02-19T10:41:27Z") +AnnotationAssertion( "GO:1905950") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "monosaccharide transport") +AnnotationAssertion( "GO:0015749") +AnnotationAssertion(rdfs:label "monosaccharide transmembrane transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (pentose transmembrane transport) + +AnnotationAssertion(Annotation( "GOC:ai") "The process in which pentose is transported across a lipid bilayer, from one side of a membrane to the other. A pentose is any aldose with a chain of five carbon atoms in the molecule.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "pentose transport") +AnnotationAssertion( "GO:0015750") +AnnotationAssertion(rdfs:label "pentose transmembrane transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (D-ribose transmembrane transport) + +AnnotationAssertion(Annotation( "GOC:ai") "The process in which D-ribose is transported across a lipid bilayer, from one side of a membrane to the other. As beta-D-ribofuranose, D-ribose forms the glycose group of all ribonucleosides, ribonucleotides and ribonucleic acids, and also of ribose phosphates, various glycosides, some coenzymes and some forms of vitamin B12.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "D-ribose transport") +AnnotationAssertion( "GO:0015752") +AnnotationAssertion(rdfs:label "D-ribose transmembrane transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (polysaccharide transport) + +AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of polysaccharides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A polysaccharide is a polymer of many (typically more than 10) monosaccharide residues linked glycosidically.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0015774") +AnnotationAssertion(rdfs:label "polysaccharide transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (acidic amino acid transport) AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of acidic amino acids, amino acids with a pH below 7, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") @@ -32410,6 +64385,38 @@ AnnotationAssertion( "acidic amino acid transport") SubClassOf( ) +# Class: (L-amino acid transport) + +AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:jsg") Annotation( "GOC:mah") "The directed movement of L-enantiomer amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0015807") +AnnotationAssertion(rdfs:label "L-amino acid transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (gamma-aminobutyric acid transport) + +AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198506732") "The directed movement of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion( "4-aminobutanoate transport") +AnnotationAssertion( "4-aminobutyrate transport") +AnnotationAssertion( "GABA transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0015812") +AnnotationAssertion(rdfs:comment "See also the biological process term 'neurotransmitter transport ; GO:0006836'.") +AnnotationAssertion(rdfs:label "gamma-aminobutyric acid transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (L-glutamate transmembrane transport) + +AnnotationAssertion(Annotation( "PMID:21307582") "The directed movement of L-glutamate across a membrane.") +AnnotationAssertion( "GO:0089711") +AnnotationAssertion( "L-glutamate transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "mitochondrial aspartate/glutamate transport") +AnnotationAssertion( "GO:0015813") +AnnotationAssertion(rdfs:label "L-glutamate transmembrane transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf( ) + # Class: (peptide transport) AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") @@ -32417,9 +64424,41 @@ AnnotationAssertion( "GO:0015833") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "peptide transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) +# Class: (amine transport) + +AnnotationAssertion(Annotation( "GOC:ai") Annotation( "ISBN:0198506732") "The directed movement of amines, including polyamines, organic compounds containing one or more amino groups, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "amine/polyamine transport") +AnnotationAssertion( "GO:0015837") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "amine transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (monoamine transport) + +AnnotationAssertion(Annotation( "GOC:mah") "The directed movement of monoamines, organic compounds that contain one amino group that is connected to an aromatic ring by an ethylene group (-CH2-CH2-), into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion( "GO:0015873") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0015844") +AnnotationAssertion(rdfs:label "monoamine transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (organic acid transport) + +AnnotationAssertion(Annotation( "ISBN:0198506732") "The directed movement of organic acids, any acidic compound containing carbon in covalent linkage, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0015849") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "organic acid transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (organic hydroxy compound transport) AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of an organic hydroxy compound (organic alcohol) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. An organic hydroxy compound is an organic compound having at least one hydroxy group attached to a carbon atom.") @@ -32427,9 +64466,222 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0015850") AnnotationAssertion(rdfs:label "organic hydroxy compound transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) +# Class: (nucleobase transport) + +AnnotationAssertion(Annotation( "ISBN:0198506732") "The directed movement of a nucleobase, any nitrogenous base that is a constituent of a nucleoside, nucleotide, or nucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion(Annotation( "GOC:mah") "nucleobase transmembrane transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0015851") +AnnotationAssertion(rdfs:label "nucleobase transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (adenine transport) + +AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198506732") "The directed movement of adenine, 6-aminopurine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion(Annotation( "GOC:mah") "adenine transmembrane transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0015853") +AnnotationAssertion(rdfs:label "adenine transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (nucleoside transport) + +AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of a nucleoside, a nucleobase linked to either beta-D-ribofuranose (ribonucleoside) or 2-deoxy-beta-D-ribofuranose, (a deoxyribonucleotide), into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0015858") +AnnotationAssertion(rdfs:label "nucleoside transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (intracellular nucleoside transport) + +AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of a nucleoside, a nucleobase linked to either beta-D-ribofuranose (ribonucleoside) or 2-deoxy-beta-D-ribofuranose, (a deoxyribonucleotide), within a cell.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0015859") +AnnotationAssertion(rdfs:label "intracellular nucleoside transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (purine nucleoside transmembrane transport) + +AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:vw") "The process in which a purine nucleoside is transported across a membrane. A purine nucleoside is a purine base covalently bonded to a ribose or deoxyribose sugar.") +AnnotationAssertion( "GO:0035427") +AnnotationAssertion(Annotation( "GOC:vw") "purine nucleoside transport") +AnnotationAssertion( "purine nucleoside membrane transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0015860") +AnnotationAssertion(rdfs:comment "Note that this term is not intended for use in annotating lateral movement within membranes.") +AnnotationAssertion(rdfs:label "purine nucleoside transmembrane transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (purine nucleotide transport) + +AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of a purine nucleotide, any compound consisting of a purine nucleoside esterified with (ortho)phosphate, into, out of or within a cell.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0015865") +AnnotationAssertion(rdfs:label "purine nucleotide transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (ADP transport) + +AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of ADP, adenosine diphosphate, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0015866") +AnnotationAssertion(rdfs:label "ADP transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (ATP transport) + +AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of ATP, adenosine triphosphate, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0015867") +AnnotationAssertion(rdfs:label "ATP transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (purine ribonucleotide transport) + +AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of a purine ribonucleotide, any compound consisting of a purine ribonucleoside (a purine organic base attached to a ribose sugar) esterified with (ortho)phosphate, into, out of or within a cell.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0015868") +AnnotationAssertion(rdfs:label "purine ribonucleotide transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (protein-DNA complex transport) + +AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of protein-DNA complexes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion(Annotation( "GOC:mah") "DNA-protein complex transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0015869") +AnnotationAssertion(rdfs:label "protein-DNA complex transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (acetylcholine transport) + +AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of acetylcholine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Acetylcholine is an acetic acid ester of the organic base choline and functions as a neurotransmitter, released at the synapses of parasympathetic nerves and at neuromuscular junctions.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0015870") +AnnotationAssertion(rdfs:label "acetylcholine transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (choline transport) + +AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of choline into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Choline (2-hydroxyethyltrimethylammonium) is an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0015871") +AnnotationAssertion(rdfs:label "choline transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (dopamine transport) + +AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of dopamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Dopamine is a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0015872") +AnnotationAssertion(rdfs:label "dopamine transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (norepinephrine transport) + +AnnotationAssertion(Annotation( "GOC:ai") Annotation( "ISBN:0198506732") "The directed movement of norepinephrine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Norepinephrine (3,4-dihydroxyphenyl-2-aminoethanol) is a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine.") +AnnotationAssertion( "levarterenol transport") +AnnotationAssertion( "noradrenaline transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0015874") +AnnotationAssertion(rdfs:label "norepinephrine transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (alkane transport) + +AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of alkanes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Alkanes are saturated aliphatic hydrocarbon compounds.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0015895") +AnnotationAssertion(rdfs:label "alkane transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (fatty acid transport) + +AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of fatty acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Fatty acids are aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0015908") +AnnotationAssertion(rdfs:label "fatty acid transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (short-chain fatty acid transport) + +AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of short-chain fatty acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A short-chain fatty acid is a fatty acid with an aliphatic tail of less than 6 carbons.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0015912") +AnnotationAssertion(rdfs:label "short-chain fatty acid transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (short-chain fatty acid transmembrane transport) + +AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of short-chain fatty acids into a cell or organelle. A short-chain fatty acid is a fatty acid with an aliphatic tail of less than 6 carbons.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/24587"^^xsd:anyURI) +AnnotationAssertion( "short-chain fatty acid uptake") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "short-chain fatty acid import") +AnnotationAssertion( "GO:0015913") +AnnotationAssertion(rdfs:label "short-chain fatty acid transmembrane transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (phospholipid transport) + +AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of phospholipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Phospholipids are any lipids containing phosphoric acid as a mono- or diester.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0015914") +AnnotationAssertion(rdfs:label "phospholipid transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (nucleobase-containing compound transport) + +AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "nucleobase, nucleoside, nucleotide and nucleic acid transport") +AnnotationAssertion( "GO:0015931") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "nucleobase-containing compound transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (nucleobase-containing compound transmembrane transporter activity) + +AnnotationAssertion(Annotation( "GOC:ai") "Enables the transfer of nucleobases, nucleosides, nucleotides and nucleic acids from one side of a membrane to the other.") +AnnotationAssertion( "molecular_function") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "nucleobase, nucleoside, nucleotide and nucleic acid transmembrane transporter activity") +AnnotationAssertion( "GO:0015932") +AnnotationAssertion(rdfs:label "nucleobase-containing compound transmembrane transporter activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (formate metabolic process) + +AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving formate, also known as methanoate, the anion HCOO- derived from methanoic (formic) acid.") +AnnotationAssertion( "formate metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0015942") +AnnotationAssertion(rdfs:label "formate metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (formate biosynthetic process) + +AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of formate, also known as methanoate, the anion HCOO- derived from methanoic (formic) acid.") +AnnotationAssertion( "formate anabolism") +AnnotationAssertion( "formate biosynthesis") +AnnotationAssertion( "formate formation") +AnnotationAssertion( "formate synthesis") +AnnotationAssertion( "formic acid biosynthesis") +AnnotationAssertion( "formic acid biosynthetic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0015943") +AnnotationAssertion(rdfs:label "formate biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (energy derivation by oxidation of organic compounds) AnnotationAssertion(Annotation( "GOC:mah") "The chemical reactions and pathways by which a cell derives energy from organic compounds; results in the oxidation of the compounds from which energy is released.") @@ -32467,6 +64719,44 @@ AnnotationAssertion(rdfs:label "memb SubClassOf( ) DisjointClasses( ) +# Class: (lipid catabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways resulting in the breakdown of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.") +AnnotationAssertion( "GO:0006724") +AnnotationAssertion( "GO:0044240") +AnnotationAssertion( "Wikipedia:Lipid_catabolism") +AnnotationAssertion( "lipid breakdown") +AnnotationAssertion( "lipid catabolism") +AnnotationAssertion( "lipid degradation") +AnnotationAssertion( "lipolysis") +AnnotationAssertion( "multicellular organism lipid catabolic process") +AnnotationAssertion( "multicellular organismal lipid catabolic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0016042") +AnnotationAssertion(rdfs:label "lipid catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (cellular component organization) + +AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:jl") Annotation( "GOC:mah") "A process that results in the assembly, arrangement of constituent parts, or disassembly of a cellular component.") +AnnotationAssertion( "GO:0044235") +AnnotationAssertion( "GO:0071842") +AnnotationAssertion( "cell organisation") +AnnotationAssertion(Annotation( "GOC:mah") "cellular component organisation at cellular level") +AnnotationAssertion(Annotation( "GOC:mah") "cellular component organisation in other organism") +AnnotationAssertion( "cellular component organization at cellular level") +AnnotationAssertion( "cellular component organization in other organism") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:mah") "cell organization and biogenesis") +AnnotationAssertion( "GO:0016043") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "cellular component organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + # Class: (detection of temperature stimulus) AnnotationAssertion(Annotation( "GOC:hb") "The series of events in which a temperature stimulus (hot or cold) is received and converted into a molecular signal.") @@ -32498,9 +64788,58 @@ AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "cell growth") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) +# Class: (vesicle organization) + +AnnotationAssertion(Annotation( "GOC:mah") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vesicle.") +AnnotationAssertion( "vesicle organisation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:mah") "vesicle organization and biogenesis") +AnnotationAssertion( "GO:0016050") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "vesicle organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (carbohydrate biosynthetic process) + +AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.") +AnnotationAssertion( "GO:0006093") +AnnotationAssertion( "anabolic carbohydrate metabolic process") +AnnotationAssertion( "anabolic carbohydrate metabolism") +AnnotationAssertion( "carbohydrate anabolism") +AnnotationAssertion( "carbohydrate biosynthesis") +AnnotationAssertion( "carbohydrate formation") +AnnotationAssertion( "carbohydrate synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0016051") +AnnotationAssertion(rdfs:label "carbohydrate biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (carbohydrate catabolic process) + +AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.") +AnnotationAssertion( "jl") +AnnotationAssertion( "2012-10-23T16:34:39Z") +AnnotationAssertion( "GO:0006095") +AnnotationAssertion( "GO:0044276") +AnnotationAssertion( "GO:0044724") +AnnotationAssertion( "carbohydrate breakdown") +AnnotationAssertion( "carbohydrate catabolism") +AnnotationAssertion( "carbohydrate degradation") +AnnotationAssertion( "catabolic carbohydrate metabolic process") +AnnotationAssertion( "catabolic carbohydrate metabolism") +AnnotationAssertion( "multicellular organismal carbohydrate catabolic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "single-organism carbohydrate catabolic process") +AnnotationAssertion( "GO:0016052") +AnnotationAssertion(rdfs:label "carbohydrate catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (organic acid biosynthetic process) AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of organic acids, any acidic compound containing carbon in covalent linkage.") @@ -32511,11 +64850,292 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0016053") AnnotationAssertion(rdfs:label "organic acid biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) +# Class: (organic acid catabolic process) + +AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of organic acids, any acidic compound containing carbon in covalent linkage.") +AnnotationAssertion( "organic acid breakdown") +AnnotationAssertion( "organic acid catabolism") +AnnotationAssertion( "organic acid degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0016054") +AnnotationAssertion(rdfs:label "organic acid catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of membrane potential in photoreceptor cell) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:hb") Annotation( "GOC:tb") "Hyperpolarization (vertebrates) or depolarization (invertebrates) of the photoreceptor cell membrane via closing/opening of cation specific channels as a result of signals generated by rhodopsin activation by a photon.") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "changes in polarization state of photoreceptor cell membrane") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0016057") +AnnotationAssertion(rdfs:label "regulation of membrane potential in photoreceptor cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (immunoglobulin mediated immune response) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "GO_REF:0000022") Annotation( "ISBN:0781735149") "An immune response mediated by immunoglobulins, whether cell-bound or in solution.") +AnnotationAssertion( "antibody-mediated immune response") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0016064") +AnnotationAssertion(rdfs:label "immunoglobulin mediated immune response") +SubClassOf( ) + +# Class: (RNA metabolic process) + +AnnotationAssertion(Annotation( "ISBN:0198506732") "The cellular chemical reactions and pathways involving RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage.") +AnnotationAssertion( "RNA metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0016070") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "RNA metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (synaptic vesicle exocytosis) + +AnnotationAssertion(Annotation( "GOC:jid") Annotation( "GOC:lmg") "Fusion of intracellular membrane-bounded vesicles with the pre-synaptic membrane of the neuronal cell resulting in release of neurotransmitter into the synaptic cleft.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0016079") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "synaptic vesicle exocytosis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (sesquiterpenoid biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways resulting in the formation of sesquiterpenoid compounds, terpenoids with three isoprene units.") +AnnotationAssertion( "sesquiterpenoid anabolism") +AnnotationAssertion( "sesquiterpenoid biosynthesis") +AnnotationAssertion( "sesquiterpenoid formation") +AnnotationAssertion( "sesquiterpenoid synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0016106") +AnnotationAssertion(rdfs:label "sesquiterpenoid biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (sesquiterpenoid catabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways resulting in the breakdown of sesquiterpenoid compounds, terpenoids with three isoprene units.") +AnnotationAssertion( "sesquiterpenoid breakdown") +AnnotationAssertion( "sesquiterpenoid catabolism") +AnnotationAssertion( "sesquiterpenoid degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0016107") +AnnotationAssertion(rdfs:label "sesquiterpenoid catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (tetraterpenoid metabolic process) + +AnnotationAssertion(Annotation( "ISBN:0198547684") "The chemical reactions and pathways involving tetraterpenoid compounds, terpenoids with eight isoprene units.") +AnnotationAssertion( "tetraterpenoid metabolism") +AnnotationAssertion( "tetraterpene metabolic process") +AnnotationAssertion( "tetraterpene metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0016108") +AnnotationAssertion(rdfs:label "tetraterpenoid metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (tetraterpenoid biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways resulting in the formation of tetraterpenoid compounds, terpenoids with eight isoprene units.") +AnnotationAssertion( "tetraterpenoid anabolism") +AnnotationAssertion( "tetraterpenoid biosynthesis") +AnnotationAssertion( "tetraterpenoid formation") +AnnotationAssertion( "tetraterpenoid synthesis") +AnnotationAssertion( "tetraterpene biosynthesis") +AnnotationAssertion( "tetraterpene biosynthetic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0016109") +AnnotationAssertion(rdfs:label "tetraterpenoid biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (tetraterpenoid catabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways resulting in the breakdown of tetraterpenoid compounds, terpenoids with eight isoprene units.") +AnnotationAssertion( "tetraterpenoid breakdown") +AnnotationAssertion( "tetraterpenoid catabolism") +AnnotationAssertion( "tetraterpenoid degradation") +AnnotationAssertion( "tetraterpene catabolic process") +AnnotationAssertion( "tetraterpene catabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0016110") +AnnotationAssertion(rdfs:label "tetraterpenoid catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (terpenoid biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways resulting in the formation of terpenoids, any member of a class of compounds characterized by an isoprenoid chemical structure.") +AnnotationAssertion( "Wikipedia:Terpenoid") +AnnotationAssertion( "terpenoid anabolism") +AnnotationAssertion( "terpenoid biosynthesis") +AnnotationAssertion( "terpenoid formation") +AnnotationAssertion( "terpenoid synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0016114") +AnnotationAssertion(rdfs:label "terpenoid biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (terpenoid catabolic process) + +AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways resulting in the breakdown of terpenoids, any member of a class of compounds characterized by an isoprenoid chemical structure.") +AnnotationAssertion( "terpenoid breakdown") +AnnotationAssertion( "terpenoid catabolism") +AnnotationAssertion( "terpenoid degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0016115") +AnnotationAssertion(rdfs:label "terpenoid catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (carotenoid metabolic process) + +AnnotationAssertion(Annotation( "ISBN:0198547684") "The chemical reactions and pathways involving carotenoids, tetraterpenoid compounds in which two units of 4 isoprenoid residues joined head-to-tail are themselves joined tail-to-tail.") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( "carotenoid metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0016116") +AnnotationAssertion(rdfs:label "carotenoid metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) +SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) +SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses( ObjectSomeValuesFrom( )) +DisjointClasses( ObjectSomeValuesFrom( )) + +# Class: (carotenoid biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways resulting in the formation of carotenoids, tetraterpenoid compounds in which two units of 4 isoprenoid residues joined head-to-tail are themselves joined tail-to-tail.") +AnnotationAssertion( "MetaCyc:CAROTENOID-PWY") +AnnotationAssertion( "carotenoid anabolism") +AnnotationAssertion( "carotenoid biosynthesis") +AnnotationAssertion( "carotenoid formation") +AnnotationAssertion( "carotenoid synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0016117") +AnnotationAssertion(rdfs:label "carotenoid biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (carotenoid catabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways resulting in the breakdown of carotenoids, tetraterpenoid compounds in which two units of 4 isoprenoid residues joined head-to-tail are themselves joined tail-to-tail.") +AnnotationAssertion( "carotenoid breakdown") +AnnotationAssertion( "carotenoid catabolism") +AnnotationAssertion( "carotenoid degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0016118") +AnnotationAssertion(rdfs:label "carotenoid catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (carotene metabolic process) + +AnnotationAssertion(Annotation( "ISBN:0198547684") "The chemical reactions and pathways involving carotenes, hydrocarbon carotenoids.") +AnnotationAssertion( "carotene metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0016119") +AnnotationAssertion(rdfs:label "carotene metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (carotene biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways resulting in the formation of carotenes, hydrocarbon carotenoids.") +AnnotationAssertion( "carotene anabolism") +AnnotationAssertion( "carotene biosynthesis") +AnnotationAssertion( "carotene formation") +AnnotationAssertion( "carotene synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0016120") +AnnotationAssertion(rdfs:label "carotene biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (carotene catabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways resulting in the breakdown of carotenes, hydrocarbon carotenoids.") +AnnotationAssertion( "carotene breakdown") +AnnotationAssertion( "carotene catabolism") +AnnotationAssertion( "carotene degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0016121") +AnnotationAssertion(rdfs:label "carotene catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (xanthophyll metabolic process) + +AnnotationAssertion(Annotation( "ISBN:0198547684") "The chemical reactions and pathways involving xanthophylls, oxygen-containing carotenoids.") +AnnotationAssertion( "xanthophyll metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0016122") +AnnotationAssertion(rdfs:label "xanthophyll metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (xanthophyll biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways resulting in the formation of xanthophylls, oxygen-containing carotenoids.") +AnnotationAssertion( "xanthophyll anabolism") +AnnotationAssertion( "xanthophyll biosynthesis") +AnnotationAssertion( "xanthophyll formation") +AnnotationAssertion( "xanthophyll synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0016123") +AnnotationAssertion(rdfs:label "xanthophyll biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (xanthophyll catabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways resulting in the breakdown of xanthophylls, oxygen-containing carotenoids.") +AnnotationAssertion( "xanthophyll breakdown") +AnnotationAssertion( "xanthophyll catabolism") +AnnotationAssertion( "xanthophyll degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0016124") +AnnotationAssertion(rdfs:label "xanthophyll catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (vesicle-mediated transport) + +AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:mah") Annotation( "ISBN:08789310662000") "A cellular transport process in which transported substances are moved in membrane-bounded vesicles; transported substances are enclosed in the vesicle lumen or located in the vesicle membrane. The process begins with a step that directs a substance to the forming vesicle, and includes vesicle budding and coating. Vesicles are then targeted to, and fuse with, an acceptor membrane.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/25421"^^xsd:anyURI) +AnnotationAssertion( "GO:0006899") +AnnotationAssertion( "vesicle transport") +AnnotationAssertion(Annotation( "GOC:mah") "vesicular transport") +AnnotationAssertion( "nonselective vesicle transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "protein sorting along secretory pathway") +AnnotationAssertion( "vesicle trafficking") +AnnotationAssertion( "GO:0016192") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "vesicle-mediated transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of striated muscle tissue development) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of striated muscle development.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0016202") +AnnotationAssertion(rdfs:label "regulation of striated muscle tissue development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + # Class: (kinase activity) AnnotationAssertion(Annotation( "ISBN:0198506732") "Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.") @@ -32534,6 +65154,48 @@ AnnotationAssertion(rdfs:label "kina SubClassOf( ) SubClassOf( ObjectHasSelf()) +# Class: (phosphorylation) + +AnnotationAssertion(Annotation( "ISBN:0198506732") "The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide.") +AnnotationAssertion( "Wikipedia:Phosphorylation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0016310") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "phosphorylation") +SubClassOf( ) + +# Class: (mushroom body development) + +AnnotationAssertion(Annotation( "PMID:8790424") "The process whose specific outcome is the progression of the mushroom body over time, from its formation to the mature structure. The mushroom body is composed of the prominent neuropil structures of the insect central brain, thought to be crucial for olfactory associated learning. These consist mainly of a bulbous calyx and tightly packaged arrays of thin parallel fibers of the Kenyon cells.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0016319") +AnnotationAssertion(rdfs:label "mushroom body development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (female meiosis chromosome segregation) + +AnnotationAssertion(Annotation( "GOC:ai") "The cell cycle process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets during the meiotic cell cycle in a female.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0016321") +AnnotationAssertion(rdfs:label "female meiosis chromosome segregation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (oocyte microtubule cytoskeleton organization) + +AnnotationAssertion(Annotation( "GOC:mtg_sensu") Annotation( "PMID:11231123") "Formation and maintenance of a polarized microtubule array originating from a microtubule-organizing center (MTOC) in the oocyte. An example of this is found in Drosophila melanogaster.") +AnnotationAssertion( "GO:0048130") +AnnotationAssertion( "oocyte microtubule cytoskeleton organisation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0016325") +AnnotationAssertion(rdfs:label "oocyte microtubule cytoskeleton organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (morphogenesis of embryonic epithelium) AnnotationAssertion(Annotation( "GOC:jl") "The process in which the anatomical structures of embryonic epithelia are generated and organized.") @@ -32543,6 +65205,53 @@ AnnotationAssertion(rdfs:label "morp SubClassOf( ) SubClassOf( ) +# Class: (dendrite development) + +AnnotationAssertion(Annotation( "GOC:aruk") Annotation( "GOC:bc") Annotation( "GOC:jl") Annotation( "ISBN:0198506732") Annotation( "PMID:22683681") "The process whose specific outcome is the progression of the dendrite over time, from its formation to the mature structure.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0016358") +AnnotationAssertion(rdfs:label "dendrite development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (somatic cell DNA recombination) + +AnnotationAssertion(Annotation( "GOC:ma") "Recombination occurring within or between DNA molecules in somatic cells.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0016444") +AnnotationAssertion(rdfs:label "somatic cell DNA recombination") +SubClassOf( ) + +# Class: (somatic diversification of immunoglobulins) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:ma") Annotation( "ISBN:0781735149") "The somatic process that results in the generation of sequence diversity of immunoglobulins.") +AnnotationAssertion( "somatic diversification of antibodies") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0016445") +AnnotationAssertion(rdfs:label "somatic diversification of immunoglobulins") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (somatic hypermutation of immunoglobulin genes) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") Annotation( "PMID:11205330") Annotation( "PMID:11205333") Annotation( "PMID:14975236") Annotation( "PMID:7813007") "Mutations occurring somatically that result in amino acid changes in the rearranged V regions of immunoglobulins.") +AnnotationAssertion( "somatic hypermutation of antibody genes") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0016446") +AnnotationAssertion(rdfs:label "somatic hypermutation of immunoglobulin genes") +SubClassOf( ) +SubClassOf( ) + +# Class: (somatic recombination of immunoglobulin gene segments) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") "The process in which immunoglobulin genes are formed through recombination of the germline genetic elements, as known as immunoglobulin gene segments, within a single locus.") +AnnotationAssertion( "somatic recombination of antibody gene segments") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0016447") +AnnotationAssertion(rdfs:label "somatic recombination of immunoglobulin gene segments") +SubClassOf( ) +SubClassOf( ) + # Class: (cell migration) AnnotationAssertion(Annotation( "GOC:cjm") Annotation( "GOC:dph") Annotation( "GOC:ems") Annotation( "GOC:pf") Annotation( "Wikipedia:Cell_migration") "The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues.") @@ -32557,6 +65266,14 @@ SubClassOf( ObjectComplementOf(Object SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) DisjointClasses( ObjectSomeValuesFrom( )) +# Class: (cytosolic transport) + +AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of substances or organelles within the cytosol.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0016482") +AnnotationAssertion(rdfs:label "cytosolic transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (protein processing) AnnotationAssertion(Annotation( "GOC:curators") Annotation( "GOC:jl") Annotation( "GOC:jsg") "Any protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein. Protein maturation is the process leading to the attainment of the full functional capacity of a protein.") @@ -32572,6 +65289,81 @@ AnnotationAssertion(rdfs:label "prot SubClassOf( ) SubClassOf( ) +# Class: (peptide hormone processing) + +AnnotationAssertion(Annotation( "GOC:mah") "The generation of a mature peptide hormone by posttranslational processing of a prohormone.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0016486") +AnnotationAssertion(rdfs:label "peptide hormone processing") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (protein-hormone receptor activity) + +AnnotationAssertion(Annotation( "GOC:mah") "Combining with a protein hormone to initiate a change in cell activity.") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0016500") +AnnotationAssertion(rdfs:label "protein-hormone receptor activity") +SubClassOf( ) + +# Class: (nucleotide receptor activity) + +AnnotationAssertion(Annotation( "GOC:signaling") Annotation( "ISBN:0198506732") "Combining with a nucleotide and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. A nucleotide is a compound that consists of a nucleoside esterified with a phosphate molecule.") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0016502") +AnnotationAssertion(rdfs:label "nucleotide receptor activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (negative regulation of angiogenesis) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of angiogenesis.") +AnnotationAssertion( "down regulation of angiogenesis") +AnnotationAssertion( "down-regulation of angiogenesis") +AnnotationAssertion( "downregulation of angiogenesis") +AnnotationAssertion( "inhibition of angiogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0016525") +AnnotationAssertion(rdfs:label "negative regulation of angiogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (sarcoplasm) + +AnnotationAssertion(Annotation( "ISBN:0198547684") "The cytoplasm of a muscle cell; includes the sarcoplasmic reticulum.") +AnnotationAssertion( ) +AnnotationAssertion( "Wikipedia:Sarcoplasm") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0016528") +AnnotationAssertion(rdfs:label "sarcoplasm") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses( ObjectSomeValuesFrom( )) + +# Class: (glutamate binding) + +AnnotationAssertion(Annotation( "GOC:ai") "Binding to glutamate, the anion of 2-aminopentanedioic acid.") +AnnotationAssertion( "glutamic acid binding") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0016595") +AnnotationAssertion(rdfs:label "glutamate binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (amino acid binding) + +AnnotationAssertion(Annotation( "GOC:ai") "Binding to an amino acid, organic acids containing one or more amino substituents.") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0016597") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "amino acid binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (transferase activity) AnnotationAssertion(Annotation( "ISBN:0198506732") "Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2.") @@ -32606,6 +65398,187 @@ AnnotationAssertion(rdfs:comment "No AnnotationAssertion(rdfs:label "transferase activity, transferring phosphorus-containing groups") SubClassOf( ) +# Class: (phosphotransferase activity, alcohol group as acceptor) + +AnnotationAssertion(Annotation( "GOC:jl") "Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to an alcohol group (acceptor).") +AnnotationAssertion( "EC:2.7.1.-") +AnnotationAssertion(Annotation(rdfs:label "abacavir + AMP => abacavir monophosphate + adenosine") "Reactome:R-HSA-2161193") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0016773") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "phosphotransferase activity, alcohol group as acceptor") +SubClassOf( ) + +# Class: (hydrolase activity) + +AnnotationAssertion(Annotation( "ISBN:0198506732") "Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc.") +AnnotationAssertion( "EC:3.-.-.-") +AnnotationAssertion(Annotation(rdfs:label "Partial proteolysis of antigen in phagolysosomes") "Reactome:R-HSA-1236938") +AnnotationAssertion(Annotation(rdfs:label "Production of AA by iPLA2 upon FCGR activation") "Reactome:R-HSA-2029475") +AnnotationAssertion(Annotation(rdfs:label "ABHD4 hydrolyses NAPE") "Reactome:R-HSA-5694583") +AnnotationAssertion(Annotation(rdfs:label "ABHD14B hydrolyses PNPB") "Reactome:R-HSA-5695964") +AnnotationAssertion(Annotation(rdfs:label "CMBL hydrolyses OM to OLMS") "Reactome:R-HSA-6786190") +AnnotationAssertion(Annotation(rdfs:label "HDHD1:Mg2+ dephosphorylates PURIDP") "Reactome:R-HSA-6788295") +AnnotationAssertion(Annotation(rdfs:label "ENPPs hydrolyse CoA-SH to PPANT, PAP") "Reactome:R-HSA-8938314") +AnnotationAssertion(Annotation(rdfs:label "Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate") "Reactome:R-HSA-8952137") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0016787") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "hydrolase activity") +SubClassOf( ) + +# Class: (hydrolase activity, acting on ester bonds) + +AnnotationAssertion(Annotation( "GOC:jl") "Catalysis of the hydrolysis of any ester bond.") +AnnotationAssertion( "EC:3.1.-.-") +AnnotationAssertion(Annotation(rdfs:label "uPAR-acyl-GPI + H2O -> uPAR + long-chain fatty acid") "Reactome:R-HSA-162729") +AnnotationAssertion(Annotation(rdfs:label "Butyrylcholinesterase hydrolyzes acyl Ghrelin") "Reactome:R-HSA-9023617") +AnnotationAssertion(Annotation(rdfs:label "Platelet-activating factor acetylhydrolase (PLA2G7) hydrolyzes acyl Ghrelin") "Reactome:R-HSA-9023619") +AnnotationAssertion(Annotation(rdfs:label "BCHE hydrolyzes ASA-") "Reactome:R-HSA-9749609") +AnnotationAssertion( "esterase activity") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0016788") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "hydrolase activity, acting on ester bonds") +SubClassOf( ) + +# Class: (G protein-coupled acetylcholine receptor activity) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:fj") Annotation( "GOC:mah") "Combining with acetylcholine and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.") +AnnotationAssertion( "GO:0004981") +AnnotationAssertion( "G protein coupled acetylcholine receptor activity") +AnnotationAssertion( "G-protein coupled acetylcholine receptor activity") +AnnotationAssertion(Annotation( "GOC:bf") "acetylcholine receptor activity, G-protein coupled") +AnnotationAssertion( "metabotropic acetylcholine receptor activity") +AnnotationAssertion( "muscarinic acetylcholine receptor activity") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0016907") +AnnotationAssertion(rdfs:label "G protein-coupled acetylcholine receptor activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (GABA receptor activity) + +AnnotationAssertion(Annotation( "GOC:jl") Annotation( "GOC:signaling") Annotation( "PMID:10637650") "Combining with gamma-aminobutyric acid (GABA), and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. (GABA, 4-aminobutyrate) is an amino acid which acts as a neurotransmitter in some organisms.") +AnnotationAssertion( "4-aminobutanoate receptor activity") +AnnotationAssertion( "4-aminobutyrate receptor activity") +AnnotationAssertion( "GABA binding") +AnnotationAssertion( "gamma-aminobutyrate binding") +AnnotationAssertion( "gamma-aminobutyric acid binding") +AnnotationAssertion( "gamma-aminobutyric acid receptor activity") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0016917") +AnnotationAssertion(rdfs:comment "See also the molecular function term 'neurotransmitter receptor activity ; GO:0030594'.") +AnnotationAssertion(rdfs:label "GABA receptor activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (peptide hormone binding) + +AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0198506732") "Binding to a peptide with hormonal activity in animals.") +AnnotationAssertion( "polypeptide hormone binding") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0017046") +AnnotationAssertion(rdfs:label "peptide hormone binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (purine nucleotide binding) + +AnnotationAssertion(Annotation( "GOC:ai") "Binding to a purine nucleotide, a compound consisting of a purine nucleoside esterified with (ortho)phosphate.") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0017076") +AnnotationAssertion(rdfs:label "purine nucleotide binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (response to insecticide) + +AnnotationAssertion(Annotation( "GOC:curators") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insecticide stimulus. Insecticides are chemicals used to kill insects.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "insecticide resistance") +AnnotationAssertion( "insecticide susceptibility/resistance") +AnnotationAssertion( "GO:0017085") +AnnotationAssertion(rdfs:label "response to insecticide") +SubClassOf( ) + +# Class: (nucleologenesis) + +AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0198506732") "A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a nucleolus, a small, dense body one or more of which are present in the nucleus of eukaryotic cells.") +AnnotationAssertion( "nucleolus biogenesis") +AnnotationAssertion(Annotation( "GOC:mah") "nucleolus assembly") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0017126") +AnnotationAssertion(rdfs:label "nucleologenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (stem cell division) + +AnnotationAssertion(Annotation( "GOC:jid") Annotation( "ISBN:0582227089") "The self-renewing division of a stem cell. A stem cell is an undifferentiated cell, in the embryo or adult, that can undergo unlimited division and give rise to one or several different cell types.") +AnnotationAssertion( ) +AnnotationAssertion( "stem cell renewal") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0017145") +AnnotationAssertion(rdfs:label "stem cell division") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses( ObjectSomeValuesFrom( )) + +# Class: (negative regulation of translation) + +AnnotationAssertion(Annotation( "GOC:isa_complete") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA.") +AnnotationAssertion( "GO:0016478") +AnnotationAssertion( "down regulation of protein biosynthetic process") +AnnotationAssertion( "down-regulation of protein biosynthetic process") +AnnotationAssertion( "downregulation of protein biosynthetic process") +AnnotationAssertion( "negative regulation of protein anabolism") +AnnotationAssertion( "negative regulation of protein biosynthesis") +AnnotationAssertion( "negative regulation of protein biosynthetic process") +AnnotationAssertion( "negative regulation of protein formation") +AnnotationAssertion( "negative regulation of protein synthesis") +AnnotationAssertion( "inhibition of protein biosynthetic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "protein biosynthesis inhibitor activity") +AnnotationAssertion( "protein biosynthetic process inhibitor activity") +AnnotationAssertion( "GO:0017148") +AnnotationAssertion(rdfs:label "negative regulation of translation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (regulation of exocytosis) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of exocytosis.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0017157") +AnnotationAssertion(rdfs:label "regulation of exocytosis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (peptidyl-tyrosine phosphorylation) + +AnnotationAssertion(Annotation( "RESID:AA0039") "The phosphorylation of peptidyl-tyrosine to form peptidyl-O4'-phospho-L-tyrosine.") +AnnotationAssertion( "RESID:AA0039") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0018108") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "peptidyl-tyrosine phosphorylation") +SubClassOf( ) +SubClassOf( ) + # Class: (heterocycle biosynthetic process) AnnotationAssertion(Annotation( "ISBN:0198547684") "The chemical reactions and pathways resulting in the formation of heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings).") @@ -32616,9 +65589,45 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0018130") AnnotationAssertion(rdfs:label "heterocycle biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) +# Class: (keratan sulfate biosynthetic process) + +AnnotationAssertion(Annotation( "ISBN:0198547684") Annotation( "RESID:AA0247") "The chemical reactions and pathways resulting in the formation of keratan sulfate, a glycosaminoglycan with repeat units consisting of beta-1,4-linked D-galactopyranosyl-beta-(1,4)-N-acetyl-D-glucosamine 6-sulfate and with variable amounts of fucose, sialic acid and mannose units; keratan sulfate chains are covalently linked by a glycosidic attachment through the trisaccharide galactosyl-galactosyl-xylose to peptidyl-threonine or serine residues.") +AnnotationAssertion( "RESID:AA0247") +AnnotationAssertion( "keratan sulfate anabolism") +AnnotationAssertion( "keratan sulfate biosynthesis") +AnnotationAssertion( "keratan sulfate formation") +AnnotationAssertion( "keratan sulfate synthesis") +AnnotationAssertion( "keratan sulphate biosynthesis") +AnnotationAssertion( "keratan sulphate biosynthetic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0018146") +AnnotationAssertion(rdfs:label "keratan sulfate biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (peptidyl-amino acid modification) + +AnnotationAssertion(Annotation( "GOC:mah") "The alteration of an amino acid residue in a peptide.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0018193") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "peptidyl-amino acid modification") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (peptidyl-tyrosine modification) + +AnnotationAssertion(Annotation( "GOC:go_curators") "The modification of peptidyl-tyrosine.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0018212") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "peptidyl-tyrosine modification") +SubClassOf( ) + # Class: (phenol-containing compound metabolic process) AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring.") @@ -32632,6 +65641,7 @@ AnnotationAssertion( "GO:0018958") AnnotationAssertion(rdfs:comment "Note that phenol metabolism is not included as a child of 'xenobiotic metabolism' because although it is synthesized industrially, phenol is also found naturally in animal wastes and other organic materials. It is often formed by the activity of microorganisms, which can chemically modify a variety of xenobiotic and naturally occurring phenolic compounds.") AnnotationAssertion(rdfs:label "phenol-containing compound metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ) @@ -32683,7 +65693,6 @@ AnnotationAssertion( "GO:0019215") AnnotationAssertion(rdfs:label "intermediate filament binding") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) # Class: (regulation of lipid metabolic process) @@ -32772,6 +65781,17 @@ SubClassOf( ObjectSomeValuesFrom( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (neuronal action potential) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:isa_complete") Annotation( "GOC:tb") "An action potential that occurs in a neuron.") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "generation of action potential") +AnnotationAssertion( "GO:0019228") +AnnotationAssertion(rdfs:label "neuronal action potential") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (proprioception) AnnotationAssertion(Annotation( "ISBN:072168677X") "The series of events by which an organism senses the position, location, orientation, and movement of the body and its parts. Proprioception is mediated by proprioceptors, sensory nerve terminals found in muscles, tendons, and joint capsules, which give information concerning movements and position of the body. The receptors in the labyrinth are sometimes also considered proprioceptors.") @@ -32802,6 +65822,162 @@ AnnotationAssertion( "response to pheromone") SubClassOf( ) +# Class: (D-ribose biosynthetic process) + +AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of D-ribose, (ribo-pentose).") +AnnotationAssertion( "D-ribose anabolism") +AnnotationAssertion( "D-ribose biosynthesis") +AnnotationAssertion( "D-ribose formation") +AnnotationAssertion( "D-ribose synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0019302") +AnnotationAssertion(rdfs:label "D-ribose biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (D-ribose catabolic process) + +AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of D-ribose (ribo-pentose).") +AnnotationAssertion( "MetaCyc:RIBOKIN-PWY") +AnnotationAssertion( "D-ribose breakdown") +AnnotationAssertion( "D-ribose catabolism") +AnnotationAssertion( "D-ribose degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0019303") +AnnotationAssertion(rdfs:label "D-ribose catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (hexose metabolic process) + +AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving a hexose, any monosaccharide with a chain of six carbon atoms in the molecule.") +AnnotationAssertion( "hexose metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0019318") +AnnotationAssertion(rdfs:label "hexose metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (hexose biosynthetic process) + +AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of hexose, any monosaccharide with a chain of six carbon atoms in the molecule.") +AnnotationAssertion( "hexose anabolism") +AnnotationAssertion( "hexose biosynthesis") +AnnotationAssertion( "hexose formation") +AnnotationAssertion( "hexose synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0019319") +AnnotationAssertion(rdfs:label "hexose biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (hexose catabolic process) + +AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of hexose, any monosaccharide with a chain of six carbon atoms in the molecule.") +AnnotationAssertion( "hexose breakdown") +AnnotationAssertion( "hexose catabolism") +AnnotationAssertion( "hexose degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0019320") +AnnotationAssertion(rdfs:label "hexose catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (pentose metabolic process) + +AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving a pentose, any monosaccharide with a chain of five carbon atoms in the molecule.") +AnnotationAssertion( "pentose metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0019321") +AnnotationAssertion(rdfs:label "pentose metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (pentose biosynthetic process) + +AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of a pentose, any monosaccharide with a chain of five carbon atoms in the molecule.") +AnnotationAssertion( "pentose anabolism") +AnnotationAssertion( "pentose biosynthesis") +AnnotationAssertion( "pentose formation") +AnnotationAssertion( "pentose synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0019322") +AnnotationAssertion(rdfs:label "pentose biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (pentose catabolic process) + +AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of a pentose, any monosaccharide with a chain of five carbon atoms in the molecule.") +AnnotationAssertion( "pentose breakdown") +AnnotationAssertion( "pentose catabolism") +AnnotationAssertion( "pentose degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0019323") +AnnotationAssertion(rdfs:label "pentose catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (phenol-containing compound catabolic process) + +AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring.") +AnnotationAssertion( "MetaCyc:PHENOLDEG-PWY") +AnnotationAssertion( "phenol-containing compound breakdown") +AnnotationAssertion( "phenol-containing compound catabolism") +AnnotationAssertion( "phenol-containing compound degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0019336") +AnnotationAssertion(rdfs:label "phenol-containing compound catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (galactolipid metabolic process) + +AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving galactolipids, any glycolipid containing one of more residues of galactose and/or N-acetylgalactosamine.") +AnnotationAssertion( "galactolipid metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0019374") +AnnotationAssertion(rdfs:label "galactolipid metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (galactolipid biosynthetic process) + +AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of galactolipids, any glycolipid containing one of more residues of galactose and/or N-acetylgalactosamine.") +AnnotationAssertion( "galactolipid anabolism") +AnnotationAssertion( "galactolipid biosynthesis") +AnnotationAssertion( "galactolipid formation") +AnnotationAssertion( "galactolipid synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0019375") +AnnotationAssertion(rdfs:label "galactolipid biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (galactolipid catabolic process) + +AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of galactolipids, any glycolipid containing one of more residues of galactose and/or N-acetylgalactosamine.") +AnnotationAssertion( "galactolipid breakdown") +AnnotationAssertion( "galactolipid catabolism") +AnnotationAssertion( "galactolipid degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0019376") +AnnotationAssertion(rdfs:label "galactolipid catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (glycolipid catabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways resulting in the breakdown of glycolipid, a class of 1,2-di-O-acylglycerols joined at oxygen 3 by a glycosidic linkage to a carbohydrate part (usually a mono-, di- or tri-saccharide).") +AnnotationAssertion( "glycolipid breakdown") +AnnotationAssertion( "glycolipid catabolism") +AnnotationAssertion( "glycolipid degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0019377") +AnnotationAssertion(rdfs:label "glycolipid catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (acetate biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways resulting in the formation of acetate, the anion of acetic acid.") +AnnotationAssertion( "acetate anabolism") +AnnotationAssertion( "acetate biosynthesis") +AnnotationAssertion( "acetate formation") +AnnotationAssertion( "acetate synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0019413") +AnnotationAssertion(rdfs:label "acetate biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (aromatic compound biosynthetic process) AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways resulting in the formation of aromatic compounds, any substance containing an aromatic carbon ring.") @@ -32814,9 +65990,35 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0019438") AnnotationAssertion(rdfs:label "aromatic compound biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) +# Class: (aromatic compound catabolic process) + +AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways resulting in the breakdown of aromatic compounds, any substance containing an aromatic carbon ring.") +AnnotationAssertion( "aromatic compound breakdown") +AnnotationAssertion( "aromatic compound catabolism") +AnnotationAssertion( "aromatic compound degradation") +AnnotationAssertion( "aromatic hydrocarbon catabolic process") +AnnotationAssertion( "aromatic hydrocarbon catabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0019439") +AnnotationAssertion(rdfs:label "aromatic compound catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (D-amino acid catabolic process) + +AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:jsg") "The chemical reactions and pathways resulting in the breakdown of D-amino acids, the D-enantiomers of amino acids.") +AnnotationAssertion( "D-amino acid breakdown") +AnnotationAssertion( "D-amino acid catabolism") +AnnotationAssertion( "D-amino acid degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0019478") +AnnotationAssertion(rdfs:label "D-amino acid catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (protein metabolic process) AnnotationAssertion(Annotation( "GOC:ma") "The chemical reactions and pathways involving a protein. Includes protein modification.") @@ -32839,8 +66041,107 @@ AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "protein metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (butyrate metabolic process) + +AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving any butyrate, the anions of butyric acid (butanoic acid), a saturated, unbranched aliphatic acid.") +AnnotationAssertion( "GO:0043437") +AnnotationAssertion( "butanoic acid metabolic process") +AnnotationAssertion( "butanoic acid metabolism") +AnnotationAssertion( "butyrate metabolism") +AnnotationAssertion( "butyric acid metabolic process") +AnnotationAssertion( "butyric acid metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0019605") +AnnotationAssertion(rdfs:label "butyrate metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (catechol-containing compound catabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways resulting in the breakdown of catechol-containing compounds. Catechol is a compound containing a pyrocatechol nucleus or substituent.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "catechol breakdown") +AnnotationAssertion( "catechol catabolic process") +AnnotationAssertion( "catechol catabolism") +AnnotationAssertion( "catechol degradation") +AnnotationAssertion( "GO:0019614") +AnnotationAssertion(rdfs:label "catechol-containing compound catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (short-chain fatty acid catabolic process) + +AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of a fatty acid with an aliphatic tail of less than 6 carbons.") +AnnotationAssertion( "MetaCyc:ACETOACETATE-DEG-PWY") +AnnotationAssertion( "short-chain fatty acid breakdown") +AnnotationAssertion( "short-chain fatty acid catabolism") +AnnotationAssertion( "short-chain fatty acid degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0019626") +AnnotationAssertion(rdfs:label "short-chain fatty acid catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (organophosphate metabolic process) + +AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving organophosphates, any phosphate-containing organic compound.") +AnnotationAssertion( "organophosphate metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0019637") +AnnotationAssertion(rdfs:label "organophosphate metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (anaerobic purine nucleobase catabolic process) + +AnnotationAssertion(Annotation( "GOC:mah") "The anaerobic chemical reactions and pathways resulting in the breakdown of purine nucleobases, yielding energy in the form of ATP.") +AnnotationAssertion( "MetaCyc:P164-PWY") +AnnotationAssertion( "MetaCyc:PWY-5044") +AnnotationAssertion( "MetaCyc:PWY-5497") +AnnotationAssertion(Annotation( "GOC:go_curators") "anaerobic purine base catabolic process") +AnnotationAssertion( "anaerobic purine base catabolism") +AnnotationAssertion( "purine base fermentation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "anaerobic purine catabolic process") +AnnotationAssertion( "purine fermentation") +AnnotationAssertion( "GO:0019653") +AnnotationAssertion(rdfs:label "anaerobic purine nucleobase catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (acetate fermentation) + +AnnotationAssertion(Annotation( "GOC:jl") Annotation( "MetaCyc:P142-PWY") "The anaerobic chemical reactions and pathways resulting in the breakdown of acetate, yielding energy in the form of ATP.") +AnnotationAssertion( ) +AnnotationAssertion( "MetaCyc:P142-PWY") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0019654") +AnnotationAssertion(rdfs:label "acetate fermentation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses( ObjectSomeValuesFrom( )) + +# Class: (nitrogenous compound fermentation) + +AnnotationAssertion(Annotation( "GOC:mah") "The anaerobic chemical reactions and pathways resulting in the breakdown of a nitrogen-containing compound, yielding energy in the form of ATP.") +AnnotationAssertion( "nitrogenous compound catabolic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0019666") +AnnotationAssertion(rdfs:label "nitrogenous compound fermentation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (ribose phosphate metabolic process) + +AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways involving ribose phosphate, any phosphorylated ribose sugar.") +AnnotationAssertion( "ribose phosphate metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0019693") +AnnotationAssertion(rdfs:label "ribose phosphate metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (choline metabolic process) AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0192801023") "The chemical reactions and pathways involving choline (2-hydroxyethyltrimethylammonium), an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine.") @@ -32848,8 +66149,38 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0019695") AnnotationAssertion(rdfs:label "choline metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (B cell mediated immunity) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "GO_REF:0000022") Annotation( "ISBN:0781735149") "Any process involved with the carrying out of an immune response by a B cell, through, for instance, the production of antibodies or cytokines, or antigen presentation to T cells.") +AnnotationAssertion( "B lymphocyte mediated immune effector process") +AnnotationAssertion( "B lymphocyte mediated immunity") +AnnotationAssertion( "B-cell mediated immune effector process") +AnnotationAssertion( "B-cell mediated immunity") +AnnotationAssertion( "B-lymphocyte mediated immune effector process") +AnnotationAssertion( "B-lymphocyte mediated immunity") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0019724") +AnnotationAssertion(rdfs:label "B cell mediated immunity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (cellular homeostasis) + +AnnotationAssertion(Annotation( "GOC:isa_complete") Annotation( "GOC:jl") Annotation( "ISBN:0395825172") "Any process involved in the maintenance of an internal steady state at the level of the cell.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0019725") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "cellular homeostasis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectAllValuesFrom( )) +DisjointClasses( ) + # Class: (antimicrobial humoral response) AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "GOC:mtg_sensu") "An immune response against microbes mediated through a body fluid. Examples of this process are seen in the antimicrobial humoral response of Drosophila melanogaster and Mus musculus.") @@ -32861,6 +66192,31 @@ AnnotationAssertion(rdfs:label "anti SubClassOf( ) SubClassOf( ) +# Class: (regulation of isoprenoid metabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving isoprenoids.") +AnnotationAssertion( "regulation of isoprenoid metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0019747") +AnnotationAssertion(rdfs:label "regulation of isoprenoid metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (secondary metabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways resulting in many of the chemical changes of compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon. In multicellular organisms secondary metabolism is generally carried out in specific cell types, and may be useful for the organism as a whole. In unicellular organisms, secondary metabolism is often used for the production of antibiotics or for the utilization and acquisition of unusual nutrients.") +AnnotationAssertion( "Wikipedia:Secondary_metabolism") +AnnotationAssertion( "secondary metabolism") +AnnotationAssertion( "secondary metabolite metabolic process") +AnnotationAssertion( "secondary metabolite metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0019748") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "secondary metabolic process") +SubClassOf( ) + # Class: (carboxylic acid metabolic process) AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving carboxylic acids, any organic acid containing one or more carboxyl (COOH) groups or anions (COO-).") @@ -32868,6 +66224,7 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0019752") AnnotationAssertion(rdfs:label "carboxylic acid metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) # Class: (one-carbon compound transport) @@ -32942,6 +66299,14 @@ AnnotationAssertion( "isoprenoid binding") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +# Class: (immunoglobulin binding) + +AnnotationAssertion(Annotation( "GOC:ma") "Binding to an immunoglobulin.") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0019865") +AnnotationAssertion(rdfs:label "immunoglobulin binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (outer membrane) AnnotationAssertion(Annotation( "GOC:go_curators") "The external membrane of Gram-negative bacteria or certain organelles such as mitochondria and chloroplasts; freely permeable to most ions and metabolites.") @@ -32974,6 +66339,54 @@ AnnotationAssertion(rdfs:comment "No AnnotationAssertion(rdfs:label "sexual reproduction") SubClassOf( ) +# Class: (cytokine binding) + +AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:bf") Annotation( "ISBN:0198599471") "Binding to a cytokine, any of a group of proteins that function to control the survival, growth and differentiation of tissues and cells, and which have autocrine and paracrine activity.") +AnnotationAssertion( ) +AnnotationAssertion( "GO:0019965") +AnnotationAssertion( "IL binding") +AnnotationAssertion( "interleukin binding") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0019955") +AnnotationAssertion(rdfs:label "cytokine binding") +SubClassOf( ) +SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses( ObjectSomeValuesFrom( )) + +# Class: (prechordal plate formation) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The formation of the prechordal plate. The prechordal plate is a thickening of the endoderm at the cranial end of the primitive streak formed by the involution of Spemann's organizer cells. The prechordal plate and the notochord induce the formation of the neural plate from the overlying ectodermal cells.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021501") +AnnotationAssertion(rdfs:label "prechordal plate formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (neural fold bending) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:15806586") "The morphogenesis of the neural fold elevations that results in the movement of the tips of the elevations towards each other in order to fuse.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021503") +AnnotationAssertion(rdfs:label "neural fold bending") +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (neural fold hinge point formation) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:13679871") Annotation( "PMID:15806586") "The formation of the median and lateral hinge points in the neural folds. These are created by apical constriction and basal expansion of the underlying neural cells. The median hinge point extends for the entire length of the neural tube, and the lateral hinge points do not form in the spinal cord region of the neural tube.") +AnnotationAssertion(Annotation( "GOC:cls") "neural fold furrowing") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021504") +AnnotationAssertion(rdfs:label "neural fold hinge point formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (anterior neuropore closure) AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The joining together of the neural folds of the rostral opening of the neural tube. The anterior neuropore appears before the process of neural tube closure is complete.") @@ -32983,6 +66396,1618 @@ AnnotationAssertion(rdfs:label "ante SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (floor plate formation) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:11262869") "The formation of a ventral region of glial cells in the neural tube that provides inductive signals for the specification of neuronal cell types. The floor plate is evident at the ventral midline by the neural fold stage.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021508") +AnnotationAssertion(rdfs:label "floor plate formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (roof plate formation) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:15936325") "The formation of a single row of glia at the dorsal midline of the developing neural tube. This region provides inductive signals for the specification of neuronal cell types and of the specification of neural crest cells. The cells comprising the roof plate are the precursors to radial glial cells.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021509") +AnnotationAssertion(rdfs:label "roof plate formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (spinal cord development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process whose specific outcome is the progression of the spinal cord over time, from its formation to the mature structure. The spinal cord primarily conducts sensory and motor nerve impulses between the brain and the peripheral nervous tissues.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021510") +AnnotationAssertion(rdfs:label "spinal cord development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (ventral spinal cord interneuron differentiation) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:11262869") "The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of ventral spinal cord interneurons. Ventral spinal cord interneurons are cells located in the ventral portion of the spinal cord that transmit signals between sensory and motor neurons and are required for reflexive responses. Differentiation includes the processes involved in commitment of a cell to a specific fate.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021514") +AnnotationAssertion(rdfs:label "ventral spinal cord interneuron differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cell differentiation in spinal cord) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:11262869") "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the spinal cord. Differentiation includes the processes involved in commitment of a cell to a specific fate.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021515") +AnnotationAssertion(rdfs:label "cell differentiation in spinal cord") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (dorsal spinal cord development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:11179871") "The process whose specific outcome is the progression of the dorsal region of the spinal cord over time, from its formation to the mature structure. The dorsal region of the mature spinal cord contains neurons that process and relay sensory input.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021516") +AnnotationAssertion(rdfs:label "dorsal spinal cord development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (ventral spinal cord development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process whose specific outcome is the progression of the ventral region of the spinal cord over time, from its formation to the mature structure. The neurons of the ventral region of the mature spinal cord participate in motor output.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021517") +AnnotationAssertion(rdfs:label "ventral spinal cord development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (spinal cord motor neuron differentiation) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:11262869") "The process in which neuroepithelial cells in the ventral neural tube acquire specialized structural and/or functional features of motor neurons. Motor neurons innervate an effector (muscle or glandular) tissue and are responsible for transmission of motor impulses from the brain to the periphery. Differentiation includes the processes involved in commitment of a cell to a specific fate.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021522") +AnnotationAssertion(rdfs:label "spinal cord motor neuron differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (somatic motor neuron differentiation) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:11262869") "The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of somatic motor neurons. Somatic motor neurons innervate skeletal muscle targets and are responsible for transmission of motor impulses from the brain to the periphery. Differentiation includes the processes involved in commitment of a cell to a specific fate.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021523") +AnnotationAssertion(rdfs:label "somatic motor neuron differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (spinal cord radial glial cell differentiation) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:16185248") "The process in which neuroepithelial cells in the ventral neural tube acquire specialized structural and/or functional features of radial glial cells. Radial cell precursors differentiate into both neuronal cell types and mature radial glial cells. Mature radial glial cells regulate the axon growth and pathfinding processes that occur during white matter patterning of the developing spinal cord. Differentiation includes the processes involved in commitment of a cell to a specific fate.") +AnnotationAssertion( "radial glial cell differentiation in spinal cord") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021531") +AnnotationAssertion(rdfs:label "spinal cord radial glial cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (neural tube patterning) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The regionalization process that regulates the coordinated growth that establishes the non-random spatial arrangement of the neural tube.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021532") +AnnotationAssertion(rdfs:label "neural tube patterning") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cell differentiation in hindbrain) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mature cells of the hindbrain. Differentiation includes the processes involved in commitment of a cell to a specific fate.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021533") +AnnotationAssertion(rdfs:label "cell differentiation in hindbrain") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectAllValuesFrom( )) + +# Class: (cell proliferation in hindbrain) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The multiplication or reproduction of cells, resulting in the expansion of a cell population in the hindbrain.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021534") +AnnotationAssertion(rdfs:label "cell proliferation in hindbrain") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectAllValuesFrom( )) + +# Class: (cell migration in hindbrain) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The orderly movement of a cell that will reside in the hindbrain.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021535") +AnnotationAssertion(rdfs:label "cell migration in hindbrain") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectAllValuesFrom( )) + +# Class: (diencephalon development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process whose specific outcome is the progression of the diencephalon over time, from its formation to the mature structure. The diencephalon is the paired caudal parts of the prosencephalon from which the thalamus, hypothalamus, epithalamus and subthalamus are derived; these regions regulate autonomic, visceral and endocrine function, and process information directed to the cerebral cortex.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021536") +AnnotationAssertion(rdfs:label "diencephalon development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (telencephalon development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:12626695") "The process whose specific outcome is the progression of the telencephalon over time, from its formation to the mature structure. The telencephalon is the paired anteriolateral division of the prosencephalon plus the lamina terminalis from which the olfactory lobes, cerebral cortex, and subcortical nuclei are derived.") +AnnotationAssertion(Annotation( "GOC:sl") Annotation( "PMID:22331407") "cerebrum development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021537") +AnnotationAssertion(rdfs:label "telencephalon development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (epithalamus development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The progression of the epithalamus over time from its initial formation until its mature state. The epithalamus is the small dorsomedial area of the thalamus including the habenular nuclei and associated fiber bundles, the pineal body, and the epithelial roof of the third ventricle.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021538") +AnnotationAssertion(rdfs:label "epithalamus development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (subthalamus development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process whose specific outcome is the progression of the subthalamus over time, from its formation to the mature structure. The subthalamus is the anterior part of the diencephalon that lies between the thalamus, hypothalamus, and tegmentum of the mesencephalon, including subthalamic nucleus, zona incerta, the fields of Forel, and the nucleus of ansa lenticularis.") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:cls") "ventral thalamus development") +AnnotationAssertion( "GO:0021539") +AnnotationAssertion(rdfs:label "subthalamus development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (corpus callosum morphogenesis) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process in which the anatomical structures of the corpus callosum are generated and organized. The corpus callosum is a thick bundle of nerve fibers comprising a commissural plate connecting the two cerebral hemispheres. It consists of contralateral axon projections that provides communications between the right and left cerebral hemispheres.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021540") +AnnotationAssertion(rdfs:label "corpus callosum morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (ammon gyrus development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process whose specific outcome is the progression of the ammon gyrus over time, from its formation to the mature structure. The ammon gyrus, often subdivided into the CA1 and CA3 regions, is one of the two interlocking gyri of the hippocampus that is rich in large pyramidal neurons.") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:cls") "Ammon's horn development") +AnnotationAssertion(Annotation( "GOC:cls") "cornu ammonis development") +AnnotationAssertion( "GO:0021541") +AnnotationAssertion(rdfs:label "ammon gyrus development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (dentate gyrus development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process whose specific outcome is the progression of the dentate gyrus over time, from its formation to the mature structure. The dentate gyrus is one of two interlocking gyri of the hippocampus. It contains granule cells, which project to the pyramidal cells and interneurons of the CA3 region of the ammon gyrus.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021542") +AnnotationAssertion(rdfs:label "dentate gyrus development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (pallium development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:12626695") "The process whose specific outcome is the progression of the pallium over time, from its formation to the mature structure. The pallium is the roof region of the telencephalon.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021543") +AnnotationAssertion(rdfs:label "pallium development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (subpallium development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:12626695") "The process whose specific outcome is the progression of the subpallium over time, from its formation to the mature structure. The subpallium is the base region of the telencephalon.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021544") +AnnotationAssertion(rdfs:label "subpallium development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cranial nerve development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process whose specific outcome is the progression of the cranial nerves over time, from its formation to the mature structure. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021545") +AnnotationAssertion(rdfs:label "cranial nerve development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (rhombomere development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process whose specific outcome is the progression of the rhombomere over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021546") +AnnotationAssertion(rdfs:label "rhombomere development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (midbrain-hindbrain boundary initiation) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:isa_complete") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:15541513") "The regionalization process that gives rise to the midbrain-hindbrain boundary. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate.") +AnnotationAssertion(Annotation( "GOC:cls") "MHB biosynthesis") +AnnotationAssertion(Annotation( "GOC:cls") "MHB formation") +AnnotationAssertion(Annotation( "GOC:cls") "midbrain-hindbrain boundary biosynthesis") +AnnotationAssertion(Annotation( "GOC:cls") "midbrain-hindbrain boundary formation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:cls") "isthmus biosynthesis") +AnnotationAssertion(Annotation( "GOC:cls") "isthmus formation") +AnnotationAssertion( "GO:0021547") +AnnotationAssertion(rdfs:label "midbrain-hindbrain boundary initiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (pons development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process whose specific outcome is the progression of the pons over time, from its formation to the mature structure. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021548") +AnnotationAssertion(rdfs:label "pons development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cerebellum development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process whose specific outcome is the progression of the cerebellum over time, from its formation to the mature structure. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. In mice, the cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021549") +AnnotationAssertion(rdfs:label "cerebellum development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (medulla oblongata development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process whose specific outcome is the progression of the medulla oblongata over time, from its formation to the mature structure. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate.") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:cls") "medulla development") +AnnotationAssertion(Annotation( "GOC:cls") "myelencephalon development") +AnnotationAssertion( "GO:0021550") +AnnotationAssertion(rdfs:label "medulla oblongata development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (central nervous system morphogenesis) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0582227089") "The process in which the anatomical structure of the central nervous system is generated and organized. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021551") +AnnotationAssertion(rdfs:label "central nervous system morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (olfactory nerve development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process whose specific outcome is the progression of the olfactory nerve over time, from its formation to the mature structure. The olfactory nerve is a collection of sensory nerve rootlets that extend down from the olfactory bulb to the olfactory mucosa of the upper parts of the nasal cavity. This nerve conducts odor information to the brainstem.") +AnnotationAssertion(Annotation( "GOC:cls") "cranial nerve 1 development") +AnnotationAssertion(Annotation( "GOC:cls") "cranial nerve I development") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:cls") "CN 1 development") +AnnotationAssertion( "GO:0021553") +AnnotationAssertion(rdfs:label "olfactory nerve development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (optic nerve development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process whose specific outcome is the progression of the optic nerve over time, from its formation to the mature structure. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain.") +AnnotationAssertion(Annotation( "GOC:cls") "cranial nerve 2 development") +AnnotationAssertion(Annotation( "GOC:cls") "cranial nerve II development") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:cls") "CN II development") +AnnotationAssertion( "GO:0021554") +AnnotationAssertion(rdfs:label "optic nerve development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (midbrain-hindbrain boundary morphogenesis) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:15541513") "The process in which the anatomical structure of the midbrain-hindbrain boundary is generated and organized. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate.") +AnnotationAssertion(Annotation( "GOC:cls") "MHB morphogenesis") +AnnotationAssertion(Annotation( "GOC:cls") "isthmus morphogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021555") +AnnotationAssertion(rdfs:label "midbrain-hindbrain boundary morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (central nervous system formation) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0582227089") "The process that gives rise to the central nervous system. This process pertains to the initial formation of a structure from unspecified parts. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain, spinal cord and spinal nerves. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021556") +AnnotationAssertion(rdfs:label "central nervous system formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (oculomotor nerve development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process whose specific outcome is the progression of the oculomotor nerve over time, from its formation to the mature structure. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle.") +AnnotationAssertion(Annotation( "GOC:cls") "cranial nerve 3 development") +AnnotationAssertion(Annotation( "GOC:cls") "cranial nerve III development") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:cls") "CN III development") +AnnotationAssertion( "GO:0021557") +AnnotationAssertion(rdfs:label "oculomotor nerve development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (trochlear nerve development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process whose specific outcome is the progression of the trochlear nerve over time, from its formation to the mature structure. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle.") +AnnotationAssertion(Annotation( "GOC:cls") "cranial nerve 4 development") +AnnotationAssertion(Annotation( "GOC:cls") "cranial nerve IV development") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:cls") "CN IV development") +AnnotationAssertion( "GO:0021558") +AnnotationAssertion(rdfs:label "trochlear nerve development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (trigeminal nerve development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process whose specific outcome is the progression of the trigeminal nerve over time, from its formation to the mature structure. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae.") +AnnotationAssertion(Annotation( "GOC:cls") "cranial nerve 5 development") +AnnotationAssertion(Annotation( "GOC:cls") "cranial nerve V development") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:cls") "CN V development") +AnnotationAssertion( "GO:0021559") +AnnotationAssertion(rdfs:label "trigeminal nerve development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (abducens nerve development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process whose specific outcome is the progression of the abducens nerve over time, from its formation to the mature structure. The motor function of the abducens nerve is to contract the lateral rectus which results in abduction of the eye.") +AnnotationAssertion(Annotation( "GOC:cls") "cranial nerve 6 development") +AnnotationAssertion(Annotation( "GOC:cls") "cranial nerve VI development") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:cls") "CN VI development") +AnnotationAssertion( "GO:0021560") +AnnotationAssertion(rdfs:label "abducens nerve development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (facial nerve development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process whose specific outcome is the progression of the facial nerve over time, from its formation to the mature structure. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial opthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives off nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities.") +AnnotationAssertion(Annotation( "GOC:cls") "cranial nerve 7 development") +AnnotationAssertion(Annotation( "GOC:cls") "cranial nerve VII development") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:cls") "CN VII development") +AnnotationAssertion( "GO:0021561") +AnnotationAssertion(rdfs:label "facial nerve development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (vestibulocochlear nerve development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process whose specific outcome is the progression of the vestibulocochlear nerve over time, from its formation to the mature structure. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea.") +AnnotationAssertion(Annotation( "GOC:cls") "CN VIII development") +AnnotationAssertion(Annotation( "PMID:11533729") "acoustic nerve development") +AnnotationAssertion(Annotation( "GOC:cls") "cranial nerve 8 development") +AnnotationAssertion(Annotation( "GOC:cls") "cranial nerve VIII development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021562") +AnnotationAssertion(rdfs:label "vestibulocochlear nerve development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (glossopharyngeal nerve development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion.") +AnnotationAssertion(Annotation( "GOC:cls") "cranial nerve 9 development") +AnnotationAssertion(Annotation( "GOC:cls") "cranial nerve IX development") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:cls") "CN IX development") +AnnotationAssertion( "GO:0021563") +AnnotationAssertion(rdfs:label "glossopharyngeal nerve development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (vagus nerve development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process whose specific outcome is the progression of the vagus nerve over time, from its formation to the mature structure. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis.") +AnnotationAssertion(Annotation( "GOC:cls") "cranial nerve X development") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:cls") "CN X development") +AnnotationAssertion(Annotation( "GOC:cls") "cranial nerve 10 development") +AnnotationAssertion( "GO:0021564") +AnnotationAssertion(rdfs:label "vagus nerve development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (accessory nerve development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process whose specific outcome is the progression of the accessory nerve over time, from its formation to the mature structure. In mice, the spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve.") +AnnotationAssertion(Annotation( "GOC:cls") "cranial nerve XI development") +AnnotationAssertion(Annotation( "PMID:11533729") "spinal accessory nerve development") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:cls") "CN XI development") +AnnotationAssertion(Annotation( "GOC:cls") "cranial nerve 11 development") +AnnotationAssertion( "GO:0021565") +AnnotationAssertion(rdfs:label "accessory nerve development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (hypoglossal nerve development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process whose specific outcome is the progression of the hypoglossal nerve over time, from its formation to the mature structure. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue.") +AnnotationAssertion(Annotation( "GOC:cls") "cranial nerve XII development") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:cls") "CN XII development") +AnnotationAssertion(Annotation( "GOC:cls") "cranial nerve 12 development") +AnnotationAssertion( "GO:0021566") +AnnotationAssertion(rdfs:label "hypoglossal nerve development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (rhombomere 1 development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process whose specific outcome is the progression of rhombomere 1 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021567") +AnnotationAssertion(rdfs:label "rhombomere 1 development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (rhombomere 2 development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process whose specific outcome is the progression of rhombomere 2 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021568") +AnnotationAssertion(rdfs:label "rhombomere 2 development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (rhombomere 3 development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process whose specific outcome is the progression of rhombomere 3 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021569") +AnnotationAssertion(rdfs:label "rhombomere 3 development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (rhombomere 4 development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process whose specific outcome is the progression of rhombomere 4 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021570") +AnnotationAssertion(rdfs:label "rhombomere 4 development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (rhombomere 5 development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process whose specific outcome is the progression of rhombomere 5 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021571") +AnnotationAssertion(rdfs:label "rhombomere 5 development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (rhombomere 6 development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process whose specific outcome is the progression of rhombomere 6 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021572") +AnnotationAssertion(rdfs:label "rhombomere 6 development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (rhombomere 7 development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process whose specific outcome is the progression of rhombomere 7 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021573") +AnnotationAssertion(rdfs:label "rhombomere 7 development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (rhombomere 8 development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process whose specific outcome is the progression of rhombomere 8 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021574") +AnnotationAssertion(rdfs:label "rhombomere 8 development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (hindbrain morphogenesis) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process in which the anatomical structure of the hindbrain is generated and organized. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "rhombencephalon morphogenesis") +AnnotationAssertion( "GO:0021575") +AnnotationAssertion(rdfs:label "hindbrain morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (hindbrain formation) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process that gives rise to the hindbrain. This process pertains to the initial formation of a structure from unspecified parts. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021576") +AnnotationAssertion(rdfs:label "hindbrain formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (hindbrain maturation) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "A developmental process, independent of morphogenetic (shape) change, that is required for the hindbrain to attain its fully functional state. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021578") +AnnotationAssertion(rdfs:label "hindbrain maturation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (medulla oblongata morphogenesis) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process in which the anatomical structure of the medulla oblongata is generated and organized. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "medulla morphogenesis") +AnnotationAssertion( "myelencephalon morphogenesis") +AnnotationAssertion( "GO:0021579") +AnnotationAssertion(rdfs:label "medulla oblongata morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (medulla oblongata formation) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process that gives rise to the medulla oblongata. This process pertains to the initial formation of a structure from unspecified parts. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "medulla biosynthesis") +AnnotationAssertion( "medulla formation") +AnnotationAssertion( "myelencephalon biosynthesis") +AnnotationAssertion( "myelencephalon formation") +AnnotationAssertion( "GO:0021580") +AnnotationAssertion(rdfs:label "medulla oblongata formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (medulla oblongata maturation) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "A developmental process, independent of morphogenetic (shape) change, that is required for the medulla oblongata to attain its fully functional state. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "medulla maturation") +AnnotationAssertion( "myelencephalon maturation") +AnnotationAssertion( "GO:0021582") +AnnotationAssertion(rdfs:label "medulla oblongata maturation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (pons morphogenesis) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process in which the anatomical structure of the pons is generated and organized. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021583") +AnnotationAssertion(rdfs:label "pons morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (pons formation) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process that gives rise to the pons. This process pertains to the initial formation of a structure from unspecified parts. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021584") +AnnotationAssertion(rdfs:label "pons formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (pons maturation) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "A developmental process, independent of morphogenetic (shape) change, that is required for the pons to attain its fully functional state. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021586") +AnnotationAssertion(rdfs:label "pons maturation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cerebellum morphogenesis) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process in which the anatomical structure of the cerebellum is generated and organized. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. The cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021587") +AnnotationAssertion(rdfs:label "cerebellum morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cerebellum formation) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process that gives rise to the cerebellum. This process pertains to the initial formation of a structure from unspecified parts. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. The cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021588") +AnnotationAssertion(rdfs:label "cerebellum formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cerebellum maturation) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellum to attain its fully functional state. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. The cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021590") +AnnotationAssertion(rdfs:label "cerebellum maturation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (ventricular system development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process whose specific outcome is the progression of the brain ventricular system over time, from its formation to the mature structure. The brain ventricular system consists of four communicating cavities within the brain that are continuous with the central canal of the spinal cord. These cavities include two lateral ventricles, the third ventricle and the fourth ventricle. Cerebrospinal fluid fills the ventricles and is produced by the choroid plexus.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021591") +AnnotationAssertion(rdfs:label "ventricular system development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (fourth ventricle development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process whose specific outcome is the progression of the fourth ventricle over time, from its formation to the mature structure. The fourth ventricle is an irregularly shaped cavity in the rhombencephalon, between the medulla oblongata, the pons, and the isthmus in front, and the cerebellum behind. It is continuous with the central canal of the cord below and with the cerebral aqueduct above, and through its lateral and median apertures it communicates with the subarachnoid space.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021592") +AnnotationAssertion(rdfs:label "fourth ventricle development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (rhombomere morphogenesis) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process in which the anatomical structure of the rhombomere is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021593") +AnnotationAssertion(rdfs:label "rhombomere morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (rhombomere formation) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process that gives rise to the rhombomere. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021594") +AnnotationAssertion(rdfs:label "rhombomere formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (abducens nerve morphogenesis) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process in which the anatomical structure of the abducens nerve is generated and organized. The motor function of the abducens nerve is to contract the lateral rectus which results in abduction of the eye.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "CN VI development") +AnnotationAssertion( "GO:0021598") +AnnotationAssertion(rdfs:label "abducens nerve morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (abducens nerve formation) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process that gives rise to the abducens nerve. This process pertains to the initial formation of a structure from unspecified parts. The motor function of the abducens nerve is to contract the lateral rectus which results in abduction of the eye.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "CN VI biosynthesis") +AnnotationAssertion( "CN VI formation") +AnnotationAssertion( "GO:0021599") +AnnotationAssertion(rdfs:label "abducens nerve formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (abducens nerve maturation) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "A developmental process, independent of morphogenetic (shape) change, that is required for the abducens nerve to attain its fully functional state. The motor function of the abducens nerve is to contract the lateral rectus which results in abduction of the eye.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "CN VI maturation") +AnnotationAssertion( "GO:0021601") +AnnotationAssertion(rdfs:label "abducens nerve maturation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cranial nerve morphogenesis) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process in which the anatomical structure of the cranial nerves are generated and organized. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021602") +AnnotationAssertion(rdfs:label "cranial nerve morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cranial nerve formation) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process that gives rise to the cranial nerves. This process pertains to the initial formation of a structure from unspecified parts. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021603") +AnnotationAssertion(rdfs:label "cranial nerve formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cranial nerve maturation) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "A developmental process, independent of morphogenetic (shape) change, that is required for a cranial nerve to attain its fully functional state. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021605") +AnnotationAssertion(rdfs:label "cranial nerve maturation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (accessory nerve maturation) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "A developmental process, independent of morphogenetic (shape) change, that is required for the accessory nerve to attain its fully functional state. The spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "CN XI maturation") +AnnotationAssertion( "spinal accessory nerve maturation") +AnnotationAssertion( "GO:0021606") +AnnotationAssertion(rdfs:label "accessory nerve maturation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (accessory nerve morphogenesis) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process in which the anatomical structure of the accessory nerve is generated and organized. The spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "CN XI morphogenesis") +AnnotationAssertion( "GO:0021607") +AnnotationAssertion(rdfs:label "accessory nerve morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (accessory nerve formation) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process that gives rise to the accessory nerve. This process pertains to the initial formation of a structure from unspecified parts. The spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "CN XI biosynthesis") +AnnotationAssertion( "CN XI formation") +AnnotationAssertion( "GO:0021608") +AnnotationAssertion(rdfs:label "accessory nerve formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (facial nerve morphogenesis) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process in which the anatomical structure of the facial nerve is generated and organized. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial opthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives of nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "CN VII morphogenesis") +AnnotationAssertion( "GO:0021610") +AnnotationAssertion(rdfs:label "facial nerve morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (facial nerve formation) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process that gives rise to the facial nerve. This process pertains to the initial formation of a structure from unspecified parts. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial opthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives of nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "CN VII biosynthesis") +AnnotationAssertion( "CN VII formation") +AnnotationAssertion( "GO:0021611") +AnnotationAssertion(rdfs:label "facial nerve formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (facial nerve maturation) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "A developmental process, independent of morphogenetic (shape) change, that is required for the facial nerve to attain its fully functional state. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial opthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives of nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "CN VII maturation") +AnnotationAssertion( "GO:0021613") +AnnotationAssertion(rdfs:label "facial nerve maturation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (glossopharyngeal nerve maturation) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "A developmental process, independent of morphogenetic (shape) change, that is required for the glossopharyngeal nerve to attain its fully functional state. Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "CN IX maturation") +AnnotationAssertion( "GO:0021614") +AnnotationAssertion(rdfs:label "glossopharyngeal nerve maturation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (glossopharyngeal nerve morphogenesis) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process in which the anatomical structure of the glossopharyngeal nerve is generated and organized. Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "CN IX morphogenesis") +AnnotationAssertion( "GO:0021615") +AnnotationAssertion(rdfs:label "glossopharyngeal nerve morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (glossopharyngeal nerve formation) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process that gives rise to the glossopharyngeal nerve. This process pertains to the initial formation of a structure from unspecified parts. Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "CN IX biosynthesis") +AnnotationAssertion( "CN IX formation") +AnnotationAssertion( "GO:0021616") +AnnotationAssertion(rdfs:label "glossopharyngeal nerve formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (hypoglossal nerve morphogenesis) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process in which the anatomical structure of the hypoglossal nerve is generated and organized. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "CN XII morphogenesis") +AnnotationAssertion( "GO:0021618") +AnnotationAssertion(rdfs:label "hypoglossal nerve morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (hypoglossal nerve maturation) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "A developmental process, independent of morphogenetic (shape) change, that is required for the hypoglossal nerve to attain its fully functional state. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "CN XII maturation") +AnnotationAssertion( "GO:0021619") +AnnotationAssertion(rdfs:label "hypoglossal nerve maturation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (hypoglossal nerve formation) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process that gives rise to the hypoglossal nerve. This process pertains to the initial formation of a structure from unspecified parts. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "CN XII biosynthesis") +AnnotationAssertion( "CN XII formation") +AnnotationAssertion( "GO:0021620") +AnnotationAssertion(rdfs:label "hypoglossal nerve formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (oculomotor nerve morphogenesis) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process in which the anatomical structure of the oculomotor nerve is generated and organized. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "CN III morphogenesis") +AnnotationAssertion( "GO:0021622") +AnnotationAssertion(rdfs:label "oculomotor nerve morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (oculomotor nerve formation) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process that gives rise to the oculomotor nerve. This process pertains to the initial formation of a structure from unspecified parts. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "CN III biosynthesis") +AnnotationAssertion( "CN III formation") +AnnotationAssertion( "GO:0021623") +AnnotationAssertion(rdfs:label "oculomotor nerve formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (oculomotor nerve maturation) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "A developmental process, independent of morphogenetic (shape) change, that is required for the oculomotor nerve to attain its fully functional state. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "CN III maturation") +AnnotationAssertion( "GO:0021625") +AnnotationAssertion(rdfs:label "oculomotor nerve maturation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (central nervous system maturation) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0582227089") "A developmental process, independent of morphogenetic (shape) change, that is required for the central nervous system to attain its fully functional state. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021626") +AnnotationAssertion(rdfs:label "central nervous system maturation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (olfactory nerve morphogenesis) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process in which the anatomical structure of the olfactory nerve is generated and organized. The olfactory nerve is a collection of sensory nerve rootlets that extend down from the olfactory bulb to the olfactory mucosa of the upper parts of the nasal cavity. This nerve conducts odor information to the brainstem.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "CN I morphogenesis") +AnnotationAssertion( "GO:0021627") +AnnotationAssertion(rdfs:label "olfactory nerve morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (olfactory nerve formation) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process that gives rise to the olfactory nerve. This process pertains to the initial formation of a structure from unspecified parts. The olfactory nerve is a collection of sensory nerve rootlets that extend down from the olfactory bulb to the olfactory mucosa of the upper parts of the nasal cavity. This nerve conducts odor information to the brainstem.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "CN I biosynthesis") +AnnotationAssertion( "CN I formation") +AnnotationAssertion( "GO:0021628") +AnnotationAssertion(rdfs:label "olfactory nerve formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (olfactory nerve maturation) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "A developmental process, independent of morphogenetic (shape) change, that is required for the olfactory nerve to attain its fully functional state. The olfactory nerve is a collection of sensory nerve rootlets that extend down from the olfactory bulb to the olfactory mucosa of the upper parts of the nasal cavity. This nerve conducts odor information to the brainstem.") +AnnotationAssertion( "CN I maturation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021630") +AnnotationAssertion(rdfs:label "olfactory nerve maturation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (optic nerve morphogenesis) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process in which the anatomical structure of the optic nerve is generated and organized. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "CN II morphogenesis") +AnnotationAssertion( "GO:0021631") +AnnotationAssertion(rdfs:label "optic nerve morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (optic nerve maturation) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "A developmental process, independent of morphogenetic (shape) change, that is required for the optic nerve to attain its fully functional state. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain.") +AnnotationAssertion( "CN II maturation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021632") +AnnotationAssertion(rdfs:label "optic nerve maturation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (optic nerve formation) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process that gives rise to the optic nerve. This process pertains to the initial formation of a structure from unspecified parts. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "CN II biosynthesis") +AnnotationAssertion( "CN II formation") +AnnotationAssertion( "GO:0021634") +AnnotationAssertion(rdfs:label "optic nerve formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (trigeminal nerve maturation) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "A developmental process, independent of morphogenetic (shape) change, that is required for the trigeminal nerve to attain its fully functional state. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "CN V maturation") +AnnotationAssertion( "GO:0021635") +AnnotationAssertion(rdfs:label "trigeminal nerve maturation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (trigeminal nerve morphogenesis) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process in which the anatomical structure of the trigeminal nerve is generated and organized. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "CN V morphogenesis") +AnnotationAssertion( "GO:0021636") +AnnotationAssertion(rdfs:label "trigeminal nerve morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (trigeminal nerve formation) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process that gives rise to the trigeminal nerve. This process pertains to the initial formation of a structure from unspecified parts. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "CN V biosynthesis") +AnnotationAssertion( "CN V formation") +AnnotationAssertion( "GO:0021638") +AnnotationAssertion(rdfs:label "trigeminal nerve formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (trochlear nerve morphogenesis) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process in which the anatomical structure of the trochlear nerve is generated and organized. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "CH IV morphogenesis") +AnnotationAssertion( "GO:0021639") +AnnotationAssertion(rdfs:label "trochlear nerve morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (trochlear nerve maturation) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "A developmental process, independent of morphogenetic (shape) change, that is required for the trochlear nerve to attain its fully functional state. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "CN IV maturation") +AnnotationAssertion( "GO:0021640") +AnnotationAssertion(rdfs:label "trochlear nerve maturation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (trochlear nerve formation) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process that gives rise to the trochlear nerve. This process pertains to the initial formation of a structure from unspecified parts. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "CN IV biosynthesis") +AnnotationAssertion( "CN IV formation") +AnnotationAssertion( "GO:0021642") +AnnotationAssertion(rdfs:label "trochlear nerve formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (vagus nerve maturation) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "A developmental process, independent of morphogenetic (shape) change, that is required for the vagus nerve to attain its fully functional state. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "CN X maturation") +AnnotationAssertion( "GO:0021643") +AnnotationAssertion(rdfs:label "vagus nerve maturation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (vagus nerve morphogenesis) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process in which the anatomical structure of the vagus nerve is generated and organized. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "CN X morphogenesis") +AnnotationAssertion( "GO:0021644") +AnnotationAssertion(rdfs:label "vagus nerve morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (vagus nerve formation) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process that gives rise to the vagus nerve. This process pertains to the initial formation of a structure from unspecified parts. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "CN X biosynthesis") +AnnotationAssertion( "CN X formation") +AnnotationAssertion( "GO:0021646") +AnnotationAssertion(rdfs:label "vagus nerve formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (vestibulocochlear nerve maturation) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "A developmental process, independent of morphogenetic (shape) change, that is required for the vestibulocochlear nerve to attain its fully functional state. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "CN VIII maturation") +AnnotationAssertion( "auditory nerve maturation") +AnnotationAssertion( "GO:0021647") +AnnotationAssertion(rdfs:label "vestibulocochlear nerve maturation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (vestibulocochlear nerve morphogenesis) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process in which the anatomical structure of the vestibulocochlear nerve is generated and organized. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "CN VIII morphogenesis") +AnnotationAssertion( "GO:0021648") +AnnotationAssertion(rdfs:label "vestibulocochlear nerve morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (vestibulocochlear nerve formation) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process that gives rise to the vestibulocochlear nerve. This process pertains to the initial formation of a structure from unspecified parts. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "CN VII formation") +AnnotationAssertion( "GO:0021650") +AnnotationAssertion(rdfs:label "vestibulocochlear nerve formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (rhombomere 1 morphogenesis) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process in which the anatomical structure of rhombomere 1 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021651") +AnnotationAssertion(rdfs:label "rhombomere 1 morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (rhombomere 1 formation) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process that gives rise to rhombomere 1. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021652") +AnnotationAssertion(rdfs:label "rhombomere 1 formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (rhombomere boundary formation) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process that gives rise to a rhombomere boundary. This process pertains to the initial formation of a boundary delimiting a rhombomere. Rhombomeres are transverse segments of the developing rhombencephalon that are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021654") +AnnotationAssertion(rdfs:label "rhombomere boundary formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (rhombomere 2 morphogenesis) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process in which the anatomical structure of rhombomere 2 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021655") +AnnotationAssertion(rdfs:label "rhombomere 2 morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (rhombomere 2 formation) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process that gives rise to rhombomere 2. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021657") +AnnotationAssertion(rdfs:label "rhombomere 2 formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (rhombomere 3 morphogenesis) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process in which the anatomical structure of rhombomere 3 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021658") +AnnotationAssertion(rdfs:label "rhombomere 3 morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (rhombomere 3 formation) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process that gives rise to rhombomere 3. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021660") +AnnotationAssertion(rdfs:label "rhombomere 3 formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (rhombomere 4 morphogenesis) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process in which the anatomical structure of rhombomere 4 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021661") +AnnotationAssertion(rdfs:label "rhombomere 4 morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (rhombomere 4 formation) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process that gives rise to rhombomere 4. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021663") +AnnotationAssertion(rdfs:label "rhombomere 4 formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (rhombomere 5 morphogenesis) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process in which the anatomical structures of rhombomere 5 are generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021664") +AnnotationAssertion(rdfs:label "rhombomere 5 morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (rhombomere 5 formation) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process that gives rise to rhombomere 5. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021666") +AnnotationAssertion(rdfs:label "rhombomere 5 formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (rhombomere 6 morphogenesis) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process in which the anatomical structure of rhombomere 6 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021667") +AnnotationAssertion(rdfs:label "rhombomere 6 morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (rhombomere 6 formation) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process that gives rise to rhombomere 6. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021669") +AnnotationAssertion(rdfs:label "rhombomere 6 formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (lateral ventricle development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process whose specific outcome is the progression of the lateral ventricles over time, from the formation to the mature structure. The two lateral ventricles are a cavity in each of the cerebral hemispheres derived from the cavity of the embryonic neural tube. They are separated from each other by the septum pellucidum, and each communicates with the third ventricle by the foramen of Monro, through which also the choroid plexuses of the lateral ventricles become continuous with that of the third ventricle.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021670") +AnnotationAssertion(rdfs:label "lateral ventricle development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (rhombomere 7 morphogenesis) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process in which the anatomical structure of rhombomere 7 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021671") +AnnotationAssertion(rdfs:label "rhombomere 7 morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (rhombomere 7 formation) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process that gives rise to rhombomere 7. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021673") +AnnotationAssertion(rdfs:label "rhombomere 7 formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (rhombomere 8 morphogenesis) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process in which the anatomical structure of rhombomere 8 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021674") +AnnotationAssertion(rdfs:label "rhombomere 8 morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (nerve development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process whose specific outcome is the progression of a nerve over time, from its formation to the mature structure.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021675") +AnnotationAssertion(rdfs:label "nerve development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (rhombomere 8 formation) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process that gives rise to rhombomere 8. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021677") +AnnotationAssertion(rdfs:label "rhombomere 8 formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (third ventricle development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process whose specific outcome is the progression of the third ventricle over time, from its formation to the mature structure. The third ventricle is the narrow cleft inferior to the corpus callosum, within the diencephalon, between the paired thalami. Its floor is formed by the hypothalamus, its anterior wall by the lamina terminalis, and its roof by ependyma, and it communicates with the fourth ventricle by the cerebral aqueduct, and with the lateral ventricles by the interventricular foramina.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021678") +AnnotationAssertion(rdfs:label "third ventricle development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cerebellar molecular layer development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process whose specific outcome is the progression of the cerebellar molecular layer nerve over time, from its formation to the mature structure. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021679") +AnnotationAssertion(rdfs:label "cerebellar molecular layer development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cerebellar Purkinje cell layer development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process whose specific outcome is the progression of the cerebellar Purkinje cell layer over time, from its formation to the mature structure. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021680") +AnnotationAssertion(rdfs:label "cerebellar Purkinje cell layer development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cerebellar granular layer development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process whose specific outcome is the progression of the cerebellar granule layer over time, from its formation to the mature structure. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021681") +AnnotationAssertion(rdfs:label "cerebellar granular layer development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (nerve maturation) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "A developmental process, independent of morphogenetic (shape) change, that is required for a nerve to attain its fully functional state.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021682") +AnnotationAssertion(rdfs:label "nerve maturation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cerebellar granular layer morphogenesis) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process in which the anatomical structure of the cerebellar granular layer is generated and organized. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021683") +AnnotationAssertion(rdfs:label "cerebellar granular layer morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cerebellar granular layer formation) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process that gives rise to the cerebellar granule layer. This process pertains to the initial formation of a structure from unspecified parts. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021684") +AnnotationAssertion(rdfs:label "cerebellar granular layer formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cerebellar granular layer maturation) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellar granular layer to attain its fully functional state. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021686") +AnnotationAssertion(rdfs:label "cerebellar granular layer maturation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cerebellar molecular layer morphogenesis) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process in which the anatomical structure of the cerebellar molecular layer is generated and organized. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021687") +AnnotationAssertion(rdfs:label "cerebellar molecular layer morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cerebellar molecular layer formation) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process that gives rise to the cerebellar molecular layer. This process pertains to the initial formation of a structure from unspecified parts. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021688") +AnnotationAssertion(rdfs:label "cerebellar molecular layer formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cerebellar molecular layer maturation) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellar molecular layer to attain its fully functional state. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021690") +AnnotationAssertion(rdfs:label "cerebellar molecular layer maturation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cerebellar Purkinje cell layer maturation) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellar Purkinje cell layer to attain its fully functional state. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021691") +AnnotationAssertion(rdfs:label "cerebellar Purkinje cell layer maturation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cerebellar Purkinje cell layer morphogenesis) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process in which the anatomical structure of the cerebellar Purkinje cell layer is generated and organized. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021692") +AnnotationAssertion(rdfs:label "cerebellar Purkinje cell layer morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cerebellar Purkinje cell layer formation) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process that gives rise to the cerebellar Purkinje cell layer. This process pertains to the initial formation of a structure from unspecified parts. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021694") +AnnotationAssertion(rdfs:label "cerebellar Purkinje cell layer formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cerebellar cortex development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process whose specific outcome is the progression of the cerebellar cortex over time, from its formation to the mature structure. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021695") +AnnotationAssertion(rdfs:label "cerebellar cortex development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cerebellar cortex morphogenesis) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process in which the anatomical structure of the cranial nerves are generated and organized. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021696") +AnnotationAssertion(rdfs:label "cerebellar cortex morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cerebellar cortex formation) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process that gives rise to the cerebellar cortex. This process pertains to the initial formation of a structure from unspecified parts. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021697") +AnnotationAssertion(rdfs:label "cerebellar cortex formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cerebellar cortex maturation) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellar cortex to attain its fully functional state. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021699") +AnnotationAssertion(rdfs:label "cerebellar cortex maturation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (developmental maturation) AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "A developmental process, independent of morphogenetic (shape) change, that is required for an anatomical structure, cell or cellular component to attain its fully functional state.") @@ -32992,12 +68017,1085 @@ AnnotationAssertion( "developmental maturation") SubClassOf( ) +# Class: (cerebellar Golgi cell differentiation) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:15157725") "The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar Golgi cell. Differentiation includes the processes involved in commitment of a neuroblast to a Golgi cell fate. A cerebellar Golgi cell is an inhibitory GABAergic interneuron found in the cerebellar cortex.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021701") +AnnotationAssertion(rdfs:label "cerebellar Golgi cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cerebellar Purkinje cell differentiation) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:15157725") "The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar Purkinje cell. Differentiation includes the processes involved in commitment of a neuroblast to a Purkinje cell fate. A Purkinje cell is an inhibitory GABAergic neuron found in the cerebellar cortex that projects to the deep cerebellar nuclei and brain stem.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021702") +AnnotationAssertion(rdfs:label "cerebellar Purkinje cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (locus ceruleus development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process whose specific outcome is the progression of the locus ceruleus over time, from its formation to the mature structure. The locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic.") +AnnotationAssertion( "locus caeruleus development") +AnnotationAssertion( "locus coeruleus development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021703") +AnnotationAssertion(rdfs:label "locus ceruleus development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (locus ceruleus morphogenesis) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process in which the anatomical structure of the locus ceruleus is generated and organized. In mice, the locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021704") +AnnotationAssertion(rdfs:label "locus ceruleus morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (locus ceruleus formation) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process that gives rise to the locus ceruleus. This process pertains to the initial formation of a structure from unspecified parts. In mice, the locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021705") +AnnotationAssertion(rdfs:label "locus ceruleus formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (locus ceruleus maturation) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "A developmental process, independent of morphogenetic (shape) change, that is required for the locus ceruleus to attain its fully functional state. The locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021706") +AnnotationAssertion(rdfs:label "locus ceruleus maturation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cerebellar granule cell differentiation) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:15157725") "The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar granule cell. Differentiation includes the processes involved in commitment of a neuroblast to a granule cell fate. A granule cell is a glutamatergic interneuron found in the cerebellar cortex.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021707") +AnnotationAssertion(rdfs:label "cerebellar granule cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cerebellar stellate cell differentiation) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:15157725") "The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar stellate cell. Differentiation includes the processes involved in commitment of a neuroblast to a cerebellar stellate cell fate. A cerebellar stellate cell is an inhibitory GABAergic interneuron found in the cerebellar cortex.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021710") +AnnotationAssertion(rdfs:label "cerebellar stellate cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (inferior olivary nucleus development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process whose specific outcome is the progression of the inferior olivary nucleus over time, from its formation to the mature structure. The inferior olivary nucleus is a capsule-shaped structure in the ventral medulla located just lateral and dorsal to the medullary pyramids. Neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex; these neurons have been implicated in various functions, such as learning and timing of movements.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "inferior olive development") +AnnotationAssertion( "GO:0021713") +AnnotationAssertion(rdfs:label "inferior olivary nucleus development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (inferior olivary nucleus morphogenesis) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process in which the anatomical structure of the inferior olivary nucleus is generated and organized. The inferior olivary nucleus is a capsule-shaped structure in the ventral medulla located just lateral and dorsal to the medullary pyramids. Neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex; these neurons have been implicated in various functions, such as learning and timing of movements.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "inferior olive morphogenesis") +AnnotationAssertion( "GO:0021714") +AnnotationAssertion(rdfs:label "inferior olivary nucleus morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (inferior olivary nucleus formation) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process that gives rise to the inferior olivary nucleus. This process pertains to the initial formation of a structure from unspecified parts. The inferior olivary nucleus is a capsule-shaped structure in the ventral medulla located just lateral and dorsal to the medullary pyramids. Neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex; these neurons have been implicated in various functions, such as learning and timing of movements.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "inferior olive biosynthesis") +AnnotationAssertion( "inferior olive formation") +AnnotationAssertion( "GO:0021715") +AnnotationAssertion(rdfs:label "inferior olivary nucleus formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (inferior olivary nucleus maturation) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "A developmental process, independent of morphogenetic (shape) change, that is required for the inferior olivary nucleus to attain its fully functional state. The inferior olivary nucleus is a capsule-shaped structure in the ventral medulla located just lateral and dorsal to the medullary pyramids. Neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex; these neurons have been implicated in various functions, such as learning and timing of movements.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "inferior olive maturation") +AnnotationAssertion( "GO:0021717") +AnnotationAssertion(rdfs:label "inferior olivary nucleus maturation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (superior olivary nucleus development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process whose specific outcome is the progression of the superior olivary nucleus over time, from its formation to the mature structure. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "superior olive development") +AnnotationAssertion( "GO:0021718") +AnnotationAssertion(rdfs:label "superior olivary nucleus development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (superior olivary nucleus morphogenesis) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process in which the anatomical structure of the superior olivary nucleus is generated and organized. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "superior olive morphogenesis") +AnnotationAssertion( "GO:0021719") +AnnotationAssertion(rdfs:label "superior olivary nucleus morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (superior olivary nucleus formation) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "The process that gives rise to the superior olivary nucleus. This process pertains to the initial formation of a structure from unspecified parts. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021720") +AnnotationAssertion(rdfs:label "superior olivary nucleus formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (superior olivary nucleus maturation) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") "A developmental process, independent of morphogenetic (shape) change, that is required for the superior olivary nucleus to attain its fully functional state. The superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "superior olive maturation") +AnnotationAssertion( "GO:0021722") +AnnotationAssertion(rdfs:label "superior olivary nucleus maturation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (medullary reticular formation development) + +AnnotationAssertion(Annotation( "GOC:cjm") Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "Wikipedia:Rhombencephalon") Annotation( "http://www.brainspan.org") "The process whose specific outcome is the progression of the medullary reticular formation over time, from its formation to the mature structure. The medullary reticular formation is a series of brain nuclei located in the medulla oblongata.") +AnnotationAssertion( "rhombencephalic reticular formation development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021723") +AnnotationAssertion(rdfs:label "medullary reticular formation development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (inferior raphe nucleus development) + +AnnotationAssertion(Annotation( "GOC:cjm") Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:cvs") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:19003874") Annotation( "ZFA:0000366") "The process whose specific outcome is the progression of the inferior raphe nucleus over time, from its formation to the mature structure.") +AnnotationAssertion( "inferior central nucleus development") +AnnotationAssertion( "posterior raphe nucleus development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021724") +AnnotationAssertion(rdfs:label "inferior raphe nucleus development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectAllValuesFrom( )) + +# Class: (superior raphe nucleus development) + +AnnotationAssertion(Annotation( "GOC:cjm") Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:cvs") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:19003874") Annotation( "ZFA:0000440") "The process whose specific outcome is the progression of the superior raphe nucleus over time, from its formation to the mature structure.") +AnnotationAssertion( "anterior raphe nucleus development") +AnnotationAssertion( "superior central nucleus development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021725") +AnnotationAssertion(rdfs:label "superior raphe nucleus development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectAllValuesFrom( )) + +# Class: (lateral reticular nucleus development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process whose specific outcome is the progression of the lateral reticular nucleus over time, from its formation to the mature structure.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021726") +AnnotationAssertion(rdfs:label "lateral reticular nucleus development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (intermediate reticular formation development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process whose specific outcome is the progression of the intermediate reticular formation over time, from its formation to the mature structure.") +AnnotationAssertion(Annotation( "http://www.brainspan.org") "intermediate reticular nucleus development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021727") +AnnotationAssertion(rdfs:label "intermediate reticular formation development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (inferior reticular formation development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process whose specific outcome is the progression of the inferior reticular formation over time, from its formation to the mature structure.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021728") +AnnotationAssertion(rdfs:label "inferior reticular formation development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (superior reticular formation development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process whose specific outcome is the progression of the superior reticular formation over time, from its formation to the mature structure.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021729") +AnnotationAssertion(rdfs:label "superior reticular formation development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (trigeminal sensory nucleus development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process whose specific outcome is the progression of the trigeminal sensory nucleus over time, from its formation to the mature structure.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021730") +AnnotationAssertion(rdfs:comment "Note that this term was placed as a child of 'brain development' because the nucleus spans multiple brain regions from midbrain to spinal cord.") +AnnotationAssertion(rdfs:label "trigeminal sensory nucleus development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (trigeminal motor nucleus development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process whose specific outcome is the progression of the trigeminal motor nucleus over time, from its formation to the mature structure.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021731") +AnnotationAssertion(rdfs:label "trigeminal motor nucleus development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (midbrain-hindbrain boundary maturation) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:15541513") "A developmental process, independent of morphogenetic (shape) change, that is required for the midbrain-hindbrain boundary to attain its fully functional state. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "MHB maturation") +AnnotationAssertion( "isthmus maturation") +AnnotationAssertion( "GO:0021732") +AnnotationAssertion(rdfs:label "midbrain-hindbrain boundary maturation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (dentate nucleus development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process whose specific outcome is the progression of the dentate nucleus over time, from its formation to the mature structure.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021735") +AnnotationAssertion(rdfs:label "dentate nucleus development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (globose nucleus development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process whose specific outcome is the progression of the globose nucleus over time, from its formation to the mature structure.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021736") +AnnotationAssertion(rdfs:label "globose nucleus development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (emboliform nucleus development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process whose specific outcome is the progression of the emboliform nucleus over time, from its formation to the mature structure.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021737") +AnnotationAssertion(rdfs:label "emboliform nucleus development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (fastigial nucleus development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process whose specific outcome is the progression of the fastigial nucleus over time, from its formation to the mature structure.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021738") +AnnotationAssertion(rdfs:label "fastigial nucleus development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (mesencephalic trigeminal nucleus development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process whose specific outcome is the progression of the mesencephalic trigeminal nucleus over time, from its formation to the mature structure.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021739") +AnnotationAssertion(rdfs:label "mesencephalic trigeminal nucleus development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (principal sensory nucleus of trigeminal nerve development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process whose specific outcome is the progression of the pontine nucleus over time, from its formation to the mature structure.") +AnnotationAssertion(Annotation( "GOC:dph") "pontine nucleus development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021740") +AnnotationAssertion(rdfs:comment "Note that this term was placed as a child of 'brain development' because the nucleus spans multiple brain regions.") +AnnotationAssertion(rdfs:label "principal sensory nucleus of trigeminal nerve development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (spinal trigeminal nucleus development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process whose specific outcome is the progression of the spinal trigeminal nucleus over time, from its formation to the mature structure.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021741") +AnnotationAssertion(rdfs:label "spinal trigeminal nucleus development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (abducens nucleus development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process whose specific outcome is the progression of the abducens nucleus over time, from its formation to the mature structure.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021742") +AnnotationAssertion(rdfs:label "abducens nucleus development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (hypoglossal nucleus development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process whose specific outcome is the progression of the hypoglossal nucleus over time, from its formation to the mature structure.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021743") +AnnotationAssertion(rdfs:label "hypoglossal nucleus development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (dorsal motor nucleus of vagus nerve development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process whose specific outcome is the progression of the dorsal motor nucleus of the vagus nerve over time, from its formation to the mature structure.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021744") +AnnotationAssertion(rdfs:label "dorsal motor nucleus of vagus nerve development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (nucleus ambiguus development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process whose specific outcome is the progression of the nucleus ambiguus over time, from its formation to the mature structure.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021745") +AnnotationAssertion(rdfs:label "nucleus ambiguus development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (solitary nucleus development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process whose specific outcome is the progression of the solitary nucleus over time, from its formation to the mature structure.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021746") +AnnotationAssertion(rdfs:label "solitary nucleus development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cochlear nucleus development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process whose specific outcome is the progression of the cochlear nucleus over time, from its formation to the mature structure.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021747") +AnnotationAssertion(rdfs:label "cochlear nucleus development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (dorsal cochlear nucleus development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process whose specific outcome is the progression of the dorsal cochlear nucleus over time, from its formation to the mature structure.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021748") +AnnotationAssertion(rdfs:label "dorsal cochlear nucleus development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (ventral cochlear nucleus development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process whose specific outcome is the progression of the ventral cochlear nucleus over time, from its formation to the mature structure.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021749") +AnnotationAssertion(rdfs:label "ventral cochlear nucleus development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (vestibular nucleus development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:16221589") "The process whose specific outcome is the progression of the vestibular nucleus over time, from its formation to the mature structure.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021750") +AnnotationAssertion(rdfs:label "vestibular nucleus development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (salivary nucleus development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process whose specific outcome is the progression of a salivary nucleus over time, from its formation to the mature structure.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021751") +AnnotationAssertion(rdfs:label "salivary nucleus development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (inferior salivary nucleus development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process whose specific outcome is the progression of the inferior salivary nucleus over time, from its formation to the mature structure.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021752") +AnnotationAssertion(rdfs:label "inferior salivary nucleus development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (superior salivary nucleus development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process whose specific outcome is the progression of the superior salivary nucleus over time, from its formation to the mature structure.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021753") +AnnotationAssertion(rdfs:label "superior salivary nucleus development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (facial nucleus development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process whose specific outcome is the progression of the facial nucleus over time, from its formation to the mature structure.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021754") +AnnotationAssertion(rdfs:label "facial nucleus development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (striatum development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0878937420") "The progression of the striatum over time from its initial formation until its mature state. The striatum is a region of the forebrain consisting of the caudate nucleus, putamen and fundus striati.") +AnnotationAssertion( "neostriatum development") +AnnotationAssertion( "striate nucleus development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021756") +AnnotationAssertion(rdfs:label "striatum development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (caudate nucleus development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0878937420") "The progression of the caudate nucleus over time from its initial formation until its mature state. The caudate nucleus is the C-shaped structures of the striatum containing input neurons involved with control of voluntary movement in the brain.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021757") +AnnotationAssertion(rdfs:label "caudate nucleus development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (putamen development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0878937420") "The progression of the putamen over time from its initial formation until its mature state. The putamen is the lens-shaped basal ganglion involved with control of voluntary movement in the brain.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021758") +AnnotationAssertion(rdfs:label "putamen development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (globus pallidus development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0878937420") "The progression of the globus pallidus over time from its initial formation until its mature state. The globus pallidus is one of the basal ganglia involved with control of voluntary movement in the brain.") +AnnotationAssertion(Annotation( "PMID:16271465") "pallidum development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021759") +AnnotationAssertion(rdfs:label "globus pallidus development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (limbic system development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0878937420") "The progression of the limbic system over time from its initial formation until its mature state. The limbic system is a collection of structures in the brain involved in emotion, motivation and emotional aspects of memory.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021761") +AnnotationAssertion(rdfs:label "limbic system development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (substantia nigra development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0838580343") Annotation( "ISBN:0878937420") "The progression of the substantia nigra over time from its initial formation until its mature state. The substantia nigra is the layer of gray substance that separates the posterior parts of the cerebral peduncles (tegmentum mesencephali) from the anterior parts; it normally includes a posterior compact part with many pigmented cells (pars compacta) and an anterior reticular part whose cells contain little pigment (pars reticularis).") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021762") +AnnotationAssertion(rdfs:label "substantia nigra development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (subthalamic nucleus development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0878937420") "The progression of the subthalamic nucleus over time from its initial formation until its mature state. The subthalamic nucleus is the lens-shaped nucleus located in the ventral part of the subthalamus on the inner aspect of the internal capsule that is concerned with the integration of somatic motor function.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "corpus luysi development") +AnnotationAssertion( "GO:0021763") +AnnotationAssertion(rdfs:label "subthalamic nucleus development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (amygdala development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0878937420") "The progression of the amygdala over time from its initial formation until its mature state. The amygdala is an almond-shaped set of neurons in the medial temporal lobe of the brain that play a key role in processing emotions such as fear and pleasure.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021764") +AnnotationAssertion(rdfs:label "amygdala development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cingulate gyrus development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0878937420") "The progression of the cingulate gyrus over time from its initial formation until its mature state. The cingulate gyrus is a ridge in the cerebral cortex located dorsal to the corpus callosum.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021765") +AnnotationAssertion(rdfs:label "cingulate gyrus development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (hippocampus development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0878937420") Annotation( "UBERON:0002421") "The progression of the hippocampus over time from its initial formation until its mature state.") +AnnotationAssertion(Annotation( "ABA:HPF") "hippocampal formation development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021766") +AnnotationAssertion(rdfs:label "hippocampus development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (mammillary body development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0878937420") "The progression of the mammillary body over time from its initial formation until its mature state. The mammillary body is a protrusion at the posterior end of the hypothalamus that contains hypothalamic nuclei.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021767") +AnnotationAssertion(rdfs:label "mammillary body development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (nucleus accumbens development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0878937420") "The progression of the nucleus accumbens over time from its initial formation until its mature state. The nucleus accumbens is a collection of pleomorphic cells in the caudal part of the anterior horn of the lateral ventricle, in the region of the olfactory tubercle, lying between the head of the caudate nucleus and the anterior perforated substance. It is part of the ventral striatum, a composite structure considered part of the basal ganglia.") +AnnotationAssertion( "ventral striatum development") +AnnotationAssertion(Annotation( "GOC:dgh") "accumbens nucleus development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021768") +AnnotationAssertion(rdfs:label "nucleus accumbens development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (orbitofrontal cortex development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0878937420") "The progression of the orbitofrontal cortex over time from its initial formation until its mature state. The orbitofrontal cortex is a cerebral cortex region located in the frontal lobe.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021769") +AnnotationAssertion(rdfs:label "orbitofrontal cortex development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (parahippocampal gyrus development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0878937420") "The progression of the parahippocampal gyrus over time from its initial formation until its mature state. The parahippocampal gyrus is a ridge in the cerebral cortex.") +AnnotationAssertion( "Wikipedia:parahippocampal_gyrus") +AnnotationAssertion(Annotation( "GOC:dgh") "hippocampal gyrus development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021770") +AnnotationAssertion(rdfs:label "parahippocampal gyrus development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (lateral geniculate nucleus development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0878937420") "The progression of the lateral geniculate nucleus over time from its initial formation until its mature state. The lateral geniculate nucleus is the primary processor of visual information received from the retina.") +AnnotationAssertion(Annotation( "GOC:dgh") "LGN development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021771") +AnnotationAssertion(rdfs:label "lateral geniculate nucleus development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (olfactory bulb development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0878937420") "The progression of the olfactory bulb over time from its initial formation until its mature state. The olfactory bulb coordinates neuronal signaling involved in the perception of smell. It receives input from the sensory neurons and outputs to the olfactory cortex.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021772") +AnnotationAssertion(rdfs:label "olfactory bulb development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (glial cell development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process aimed at the progression of a glial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021782") +AnnotationAssertion(rdfs:label "glial cell development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (preganglionic parasympathetic fiber development) + +AnnotationAssertion(Annotation( "GOC:cjm") Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process whose specific outcome is the progression of a preganglionic parasympathetic fiber over time, from its formation to the mature structure. A preganglionic parasympathetic fiber is a cholinergic axonal fiber projecting from the CNS to a parasympathetic ganglion.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021783") +AnnotationAssertion(rdfs:label "preganglionic parasympathetic fiber development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (postganglionic parasympathetic fiber development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process whose specific outcome is the progression of the postganglionic portion of the parasympathetic fiber over time, from its formation to the mature structure. The parasympathetic fiber is one of the two divisions of the vertebrate autonomic nervous system. Parasympathetic nerves emerge cranially as pre ganglionic fibers from oculomotor, facial, glossopharyngeal and vagus and from the sacral region of the spinal cord. Most neurons are cholinergic and responses are mediated by muscarinic receptors. The parasympathetic system innervates, for example: salivary glands, thoracic and abdominal viscera, bladder and genitalia.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021784") +AnnotationAssertion(rdfs:label "postganglionic parasympathetic fiber development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (thalamus development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process in which the thalamus changes over time, from its initial formation to its mature state.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021794") +AnnotationAssertion(rdfs:label "thalamus development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cerebral cortex cell migration) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The orderly movement of cells from one site to another in the cerebral cortex.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021795") +AnnotationAssertion(rdfs:label "cerebral cortex cell migration") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cerebral cortex radially oriented cell migration) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:12626695") "The migration of cells in the developing cerebral cortex in which cells move from the ventricular and/or subventricular zone toward the surface of the brain.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021799") +AnnotationAssertion(rdfs:label "cerebral cortex radially oriented cell migration") +SubClassOf( ) + +# Class: (cerebral cortex radial glia-guided migration) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:12626695") "The radial migration of neuronal or glial precursor cells along radial glial cells during the development of the cerebral cortex.") +AnnotationAssertion( "cerebral cortex radial glia guided migration") +AnnotationAssertion( "cerebral cortex radial glia-dependent cell migration") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "PMID:12626695") "glial-guided locomotion") +AnnotationAssertion( "GO:0021801") +AnnotationAssertion(rdfs:label "cerebral cortex radial glia-guided migration") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cell motility involved in cerebral cortex radial glia guided migration) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:12626695") "The movement of a cell along the process of a radial glial cell involved in cerebral cortex glial-mediated radial migration.") +AnnotationAssertion(Annotation( "GOC:dph") "cell locomotion involved in cerebral cortex glial-mediated radial migration") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") "cell locomotion involved in cerebral cortex radial glia guided migration") +AnnotationAssertion( "GO:0021814") +AnnotationAssertion(rdfs:label "cell motility involved in cerebral cortex radial glia guided migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:12626695") "Rearrangements of the microtubule cytoskeleton that contribute to the movement of cells along radial glial cells as a component of the process of cerebral cortex glial-mediated radial migration.") +AnnotationAssertion(Annotation( "GOC:dph") "modulation of microtubule cytoskeleton involved in cerebral cortex glial-mediated radial migration") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021815") +AnnotationAssertion(rdfs:label "modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (layer formation in cerebral cortex) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:12626695") "The detachment of cells from radial glial fibers at the appropriate time when they cease to migrate and form distinct layer in the cerebral cortex.") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "PMID:12626695") "cerebral cortex lamination") +AnnotationAssertion( "GO:0021819") +AnnotationAssertion(rdfs:label "layer formation in cerebral cortex") +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (negative regulation of cell motility involved in cerebral cortex radial glia guided migration) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GOC:tb") Annotation( "GO_REF:0000021") Annotation( "PMID:12626695") "The intracellular signaling pathway that results in the cessation of cell movement involved in lamination of the cerebral cortex.") +AnnotationAssertion( "down regulation of cell locomotion involved in cerebral cortex glial-mediated radial cell migration") +AnnotationAssertion( "down-regulation of cell locomotion involved in cerebral cortex glial-mediated radial cell migration") +AnnotationAssertion( "downregulation of cell locomotion involved in cerebral cortex glial-mediated radial cell migration") +AnnotationAssertion(Annotation( "GOC:dph") "negative regulation of cell locomotion involved in cerebral cortex glial-mediated radial migration") +AnnotationAssertion( "inhibition of cell locomotion involved in cerebral cortex glial-mediated radial cell migration") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "negative regulation of cell locomotion involved in cerebral cortex radial glia guided migration") +AnnotationAssertion( "GO:0021822") +AnnotationAssertion(rdfs:label "negative regulation of cell motility involved in cerebral cortex radial glia guided migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (substrate-independent telencephalic tangential migration) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:12626695") "The process where neuronal precursors migrate tangentially in the telencephalon, primarily guided by interactions that do not require cell-cell contact.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021826") +AnnotationAssertion(rdfs:label "substrate-independent telencephalic tangential migration") +SubClassOf( ) + +# Class: (interneuron migration from the subpallium to the cortex) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:12626695") "The directed movement of interneurons from the subpallium to the cortex during forebrain development.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021830") +AnnotationAssertion(rdfs:label "interneuron migration from the subpallium to the cortex") +SubClassOf( ) + +# Class: (substrate-independent telencephalic tangential interneuron migration) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:12626695") "The directional movement of tangentially migrating interneurons that are not guided by attaching to extracellular substrates.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021843") +AnnotationAssertion(rdfs:label "substrate-independent telencephalic tangential interneuron migration") +SubClassOf( ) + +# Class: (cell proliferation in forebrain) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The creation of greater cell numbers in the forebrain due to cell division of progenitor cells.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021846") +AnnotationAssertion(rdfs:label "cell proliferation in forebrain") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (neuroblast division in subpallium) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:12626695") "The division of neuroblasts in the subpallium area of the forebrain. The interneuron precursors that these cells give rise to include GABAergic interneurons and will migrate tangentially.") +AnnotationAssertion(Annotation( "PMID:16226447") "neuroblast division in the ventral telencephalon") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021848") +AnnotationAssertion(rdfs:label "neuroblast division in subpallium") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (neuroblast division in subventricular zone) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:12626695") "The division of neuroblasts in the subventricular zone of the forebrain. The interneuron precursors that these cells give rise to include adult olfactory bulb interneurons and migrate tangentially.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021849") +AnnotationAssertion(rdfs:label "neuroblast division in subventricular zone") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (pyramidal neuron migration to cerebral cortex) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:12626695") Annotation( "PMID:22192824") "The migration of a pyramidal neuron precursor from the ventricular zone to the correct layer of the cerebral cortex.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/21476"^^xsd:anyURI) +AnnotationAssertion( "pyramidal neuron migration") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "PMID:12626695") "projection neuron migration") +AnnotationAssertion( "GO:0021852") +AnnotationAssertion(rdfs:label "pyramidal neuron migration to cerebral cortex") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cerebral cortex GABAergic interneuron migration) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:12626695") "The migration of GABAergic interneuron precursors from the subpallium to the cerebral cortex.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021853") +AnnotationAssertion(rdfs:label "cerebral cortex GABAergic interneuron migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (hypothalamus development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The progression of the hypothalamus region of the forebrain, from its initial formation to its mature state.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021854") +AnnotationAssertion(rdfs:label "hypothalamus development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (pyramidal neuron differentiation) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process in which a neuroblast or one of its progeny commits to a pyramidal neuron fate, migrates from the ventricular zone to the appropriate layer in the cortex and develops into a mature neuron.") +AnnotationAssertion(Annotation( "PMID:16226447") "projection neuron differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021859") +AnnotationAssertion(rdfs:label "pyramidal neuron differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (pyramidal neuron development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The progression of a pyramidal neuron from its initial formation to its mature state.") +AnnotationAssertion(Annotation( "PMID:16226447") "projection neuron development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021860") +AnnotationAssertion(rdfs:label "pyramidal neuron development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (forebrain radial glial cell differentiation) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:16226447") "The process in which neuroepithelial cells of the neural tube give rise to radial glial cells, specialized bipotential progenitors cells of the forebrain. Differentiation includes the processes involved in commitment of a cell to a specific fate.") +AnnotationAssertion( "radial glial cell differentiation in forebrain") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021861") +AnnotationAssertion(rdfs:label "forebrain radial glial cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (forebrain neuroblast differentiation) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:16226447") "The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of basal progenitor cells, neuroblasts that lose their contacts with the ventricular surface. Differentiation includes the processes involved in commitment of a cell to a specific fate.") +AnnotationAssertion(Annotation( "PMID:16226447") "abventricular progenitor cell differentiation") +AnnotationAssertion(Annotation( "PMID:16226447") "intermediate progenitor cell differentiation") +AnnotationAssertion(Annotation( "PMID:16226447") "non-surface dividing progenitor cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021863") +AnnotationAssertion(rdfs:label "forebrain neuroblast differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (forebrain generation of neurons) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process in which nerve cells are generated in the forebrain. This includes the production of neuroblasts from and their differentiation into neurons.") +AnnotationAssertion( "generation of neurons in forebrain") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021872") +AnnotationAssertion(rdfs:label "forebrain generation of neurons") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (forebrain neuron differentiation) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:16226447") "The process in which a relatively unspecialized cell acquires specialized features of a neuron that will reside in the forebrain.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021879") +AnnotationAssertion(rdfs:label "forebrain neuron differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (forebrain neuron development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process whose specific outcome is the progression of a neuron that resides in the forebrain, from its initial commitment to its fate, to the fully functional differentiated cell.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021884") +AnnotationAssertion(rdfs:label "forebrain neuron development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (forebrain cell migration) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The orderly movement of a cell from one site to another at least one of which is located in the forebrain.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021885") +AnnotationAssertion(rdfs:label "forebrain cell migration") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (olfactory bulb interneuron differentiation) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:12626695") "The process in which a neuroblast acquires specialized features of an interneuron residing in the olfactory bulb.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021889") +AnnotationAssertion(rdfs:label "olfactory bulb interneuron differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (olfactory bulb interneuron development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:12626695") "The process whose specific outcome is the progression of an interneuron residing in the olfactory bulb, from its initial commitment, to the fully functional differentiated cell.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021891") +AnnotationAssertion(rdfs:label "olfactory bulb interneuron development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cerebral cortex GABAergic interneuron differentiation) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:12626695") "The process in which a relatively unspecialized cell acquires specialized features of a GABAergic interneuron residing in the cerebral cortex.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021892") +AnnotationAssertion(rdfs:label "cerebral cortex GABAergic interneuron differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (cerebral cortex GABAergic interneuron development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:12626695") "The process whose specific outcome is the progression of a cerebral cortex GABAergic interneuron over time, from initial commitment to its fate, to the fully functional differentiated cell.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021894") +AnnotationAssertion(rdfs:label "cerebral cortex GABAergic interneuron development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cerebral cortex neuron differentiation) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process in which a relatively unspecialized cell acquires specialized features of a neuron residing in the cerebral cortex.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021895") +AnnotationAssertion(rdfs:label "cerebral cortex neuron differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (forebrain astrocyte differentiation) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:16226447") "The process in which a relatively unspecialized cell acquires the specialized features of an astrocyte residing in the forebrain. An astrocyte is the most abundant type of glial cell. Astrocytes provide support for neurons and regulate the environment in which they function.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021896") +AnnotationAssertion(rdfs:label "forebrain astrocyte differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (forebrain astrocyte development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process aimed at the progression of an astrocyte that resides in the forebrain, from initial commitment of the cell to its fate, to the fully functional differentiated cell. An astrocyte is the most abundant type of glial cell. Astrocytes provide support for neurons and regulate the environment in which they function.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021897") +AnnotationAssertion(rdfs:label "forebrain astrocyte development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (rostrocaudal neural tube patterning) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:11262869") "The process in which the neural tube is divided into specific regions along the rostrocaudal axis.") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") "anterior-posterior neural tube patterning") +AnnotationAssertion( "GO:0021903") +AnnotationAssertion(rdfs:label "rostrocaudal neural tube patterning") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (forebrain-midbrain boundary formation) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:11262869") "The process whose specific outcome is the creation of the forebrain-midbrain boundary.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021905") +AnnotationAssertion(rdfs:label "forebrain-midbrain boundary formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (hindbrain-spinal cord boundary formation) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:11262869") "The process whose specific outcome is the formation of the hindbrain-spinal cord boundary.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021906") +AnnotationAssertion(rdfs:label "hindbrain-spinal cord boundary formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (neural tube development) AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process whose specific outcome is the progression of the neural tube over time, from its formation to the mature structure. The mature structure of the neural tube exists when the tube has been segmented into the forebrain, midbrain, hindbrain and spinal cord regions. In addition neural crest has budded away from the epithelium.") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0021915") AnnotationAssertion(rdfs:label "neural tube development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ) @@ -33005,6 +69103,287 @@ SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (regulation of cell proliferation in dorsal spinal cord) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process that modulates the frequency, rate or extent of cell proliferation in the dorsal spinal cord.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021921") +AnnotationAssertion(rdfs:label "regulation of cell proliferation in dorsal spinal cord") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (central nervous system projection neuron axonogenesis) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body towards target cells in a different central nervous system region.") +AnnotationAssertion(Annotation( "GOC:dph") "central nervous system axon tract development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021952") +AnnotationAssertion(rdfs:label "central nervous system projection neuron axonogenesis") +SubClassOf( ) + +# Class: (central nervous system neuron differentiation) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process in which a relatively unspecialized cell acquires specialized features of a neuron whose cell body resides in the central nervous system.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021953") +AnnotationAssertion(rdfs:label "central nervous system neuron differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (central nervous system neuron development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process whose specific outcome is the progression of a neuron whose cell body is located in the central nervous system, from initial commitment of the cell to a neuronal fate, to the fully functional differentiated neuron.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021954") +AnnotationAssertion(rdfs:label "central nervous system neuron development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (central nervous system neuron axonogenesis) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "Generation of a long process from a neuron whose cell body resides in the central nervous system. The process carries efferent (outgoing) action potentials from the cell body towards target cells.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021955") +AnnotationAssertion(rdfs:label "central nervous system neuron axonogenesis") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (corticospinal tract morphogenesis) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:9878731") "Generation of a long process of a pyramidal cell, that carries efferent (outgoing) action potentials from the cell body in cerebral cortex layer V towards target cells in the gray matter of the spinal cord. This axonal process is a member of those that make up the corticospinal tract.") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:9878731") "CST axonogenesis") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:9878731") "corticospinal tract axonogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021957") +AnnotationAssertion(rdfs:label "corticospinal tract morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (gracilis tract morphogenesis) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:12867698") "Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the dorsal root ganglion towards target cells in the medulla. This axonal process is a member of those that make up the gracilis tract, a group of axons that are from neurons involved in proprioception from the lower trunk and lower limb.") +AnnotationAssertion(Annotation( "PMID:12867698") "tract of Goll morphogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021958") +AnnotationAssertion(rdfs:label "gracilis tract morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (cuneatus tract morphogenesis) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:12867698") "Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the dorsal root ganglion towards target cells in the medulla. This axonal process is a member of those that make up the cuneatus tract, a group of axons that are from neurons involved in proprioception from the upper trunk and upper limb.") +AnnotationAssertion(Annotation( "PMID:12867698") "tract of Burdach morphogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021959") +AnnotationAssertion(rdfs:label "cuneatus tract morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (anterior commissure morphogenesis) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0878937420") "Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in one half of the cerebral cortex towards target cells in the contralateral half. This axonal process is a member of those that make up the anterior commissure, a small midline fiber tract that lies at the anterior end of the corpus callosum.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021960") +AnnotationAssertion(rdfs:label "anterior commissure morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (posterior commissure morphogenesis) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the midbrain towards target cells in the diencephalon.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021961") +AnnotationAssertion(rdfs:label "posterior commissure morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (vestibulospinal tract morphogenesis) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the vestibular nucleus of the pons towards target cells in the spinal cord.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021962") +AnnotationAssertion(rdfs:label "vestibulospinal tract morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (spinothalamic tract morphogenesis) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the spinal cord towards target cells in the thalamus. This axonal process is a member of those that make up the spinothalamic tract, one of the major routes of nociceptive signaling.") +AnnotationAssertion( "dorsolateral tract of Lissauer morphogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021963") +AnnotationAssertion(rdfs:label "spinothalamic tract morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (rubrospinal tract morphogenesis) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the red nucleus of the midbrain towards target cells in the spinal cord.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021964") +AnnotationAssertion(rdfs:label "rubrospinal tract morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (spinal cord ventral commissure morphogenesis) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process in which the anatomical structures of the spinal cord ventral commissure are generated and organized.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021965") +AnnotationAssertion(rdfs:label "spinal cord ventral commissure morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (trigeminothalamic tract morphogenesis) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0878937420") "Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in spinal cord towards target cells in the thalamus. This axonal process is a member of those that make up the trigeminothalamic tract, one of the major routes of nociceptive and temperature signaling from the face.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021974") +AnnotationAssertion(rdfs:label "trigeminothalamic tract morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (pons reticulospinal tract morphogenesis) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the pons towards target cells in the spinal cord.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021975") +AnnotationAssertion(rdfs:label "pons reticulospinal tract morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (medulla reticulospinal tract morphogenesis) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the medulla towards target cells in the spinal cord.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021976") +AnnotationAssertion(rdfs:label "medulla reticulospinal tract morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (tectospinal tract morphogenesis) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the superior colliculus of the midbrain towards target cells in the ventral spinal cord.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021977") +AnnotationAssertion(rdfs:label "tectospinal tract morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (pineal gland development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The progression of the pineal gland over time from its initial formation until its mature state. The pineal gland is an endocrine gland that secretes melatonin and is involved in circadian rhythms.") +AnnotationAssertion(Annotation( "GOC:dph") "epiphysis development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021982") +AnnotationAssertion(rdfs:label "pineal gland development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (pituitary gland development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The progression of the pituitary gland over time from its initial formation until its mature state. The pituitary gland is an endocrine gland that secretes hormones that regulate many other glands.") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") "hypophysis development") +AnnotationAssertion( "GO:0021983") +AnnotationAssertion(rdfs:label "pituitary gland development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (adenohypophysis development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The progression of the adenohypophysis over time from its initial formation until its mature state. The adenohypophysis is the anterior part of the pituitary. It secretes a variety of hormones and its function is regulated by the hypothalamus.") +AnnotationAssertion( "adenophysis development") +AnnotationAssertion( "anterior pituitary development") +AnnotationAssertion( "anterior pituitary gland development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021984") +AnnotationAssertion(rdfs:label "adenohypophysis development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (neurohypophysis development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The progression of the neurohypophysis over time from its initial formation until its mature state. The neurohypophysis is the part of the pituitary gland that secretes hormones involved in blood pressure regulation.") +AnnotationAssertion( "neurophysis development") +AnnotationAssertion( "posterior pituitary development") +AnnotationAssertion( "posterior pituitary gland development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021985") +AnnotationAssertion(rdfs:label "neurohypophysis development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (habenula development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:9780721601465") "The progression of the habenula over time from its initial formation until its mature state. The habenula is the group of nuclei that makes up the stalk of the pineal gland.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021986") +AnnotationAssertion(rdfs:label "habenula development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cerebral cortex development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The progression of the cerebral cortex over time from its initial formation until its mature state. The cerebral cortex is the outer layered region of the telencephalon.") +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "PMID:25904839") "corticogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") "neocortex development") +AnnotationAssertion( "GO:0021987") +AnnotationAssertion(rdfs:label "cerebral cortex development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (olfactory lobe development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The progression of the olfactory lobe over time from its initial formation until its mature state. The olfactory lobe is the area of the brain that process the neural inputs for the sense of smell.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021988") +AnnotationAssertion(rdfs:label "olfactory lobe development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (olfactory cortex development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The progression of the olfactory cortex over time from its initial formation until its mature state. The olfactory cortex is involved in the perception of smell. It receives input from the olfactory bulb and is responsible for the identification of odors.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021989") +AnnotationAssertion(rdfs:label "olfactory cortex development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (neural plate formation) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0878932437") Annotation( "ISBN:0878932585") Annotation( "PMID:15806586") "The formation of the flat, thickened layer of ectodermal cells known as the neural plate. The underlying dorsal mesoderm signals the ectodermal cells above it to elongate into columnar neural plate cells. The neural plate subsequently develops into the neural tube, which gives rise to the central nervous system.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021990") +AnnotationAssertion(rdfs:label "neural plate formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (neuropore closure) AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process of joining together the neural folds at either end of the neural tube.") @@ -33014,6 +69393,38 @@ AnnotationAssertion(rdfs:label "neur SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (lamina terminalis formation) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process in which the anterior-most portion of the neural axis is formed by closure of the anterior neuropore.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0021996") +AnnotationAssertion(rdfs:label "lamina terminalis formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (neural plate anterior/posterior regionalization) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process that regulates the coordinated growth and differentiation that establishes the non-random anterior-posterior spatial arrangement of the neural plate.") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") "neural plate anterior/posterior pattern formation") +AnnotationAssertion( "GO:0021999") +AnnotationAssertion(rdfs:label "neural plate anterior/posterior regionalization") +SubClassOf( ) +SubClassOf( ) + +# Class: (zona limitans intrathalamica formation) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:11425897") Annotation( "PMID:16452095") "The formation of the narrow stripe of cells that lies between the prospective dorsal and ventral thalami. This boundary contains signals that pattern the prethalamic and thalamic territories of the future mid-diencephalon.") +AnnotationAssertion( "zli biosynthesis") +AnnotationAssertion( "zli formation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0022006") +AnnotationAssertion(rdfs:label "zona limitans intrathalamica formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (neurogenesis) AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "Generation of cells within the nervous system.") @@ -33026,6 +69437,142 @@ AnnotationAssertion(rdfs:label "neur SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (central nervous system vasculogenesis) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The differentiation of endothelial cells from progenitor cells during blood vessel development, and the de novo formation of blood vessels and tubes in the central nervous system. The capillary endothelial cells in the brain are specialized to form the blood-brain barrier.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/21480"^^xsd:anyURI) +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0022009") +AnnotationAssertion(rdfs:label "central nervous system vasculogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (central nervous system myelination) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process in which neuronal axons and dendrites become coated with a segmented lipid-rich sheath (myelin) to enable faster and more energetically efficient conduction of electrical impulses. The sheath is formed by the cell membranes of oligodendrocytes in the central nervous system. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier.") +AnnotationAssertion( "myelination in central nervous system") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0022010") +AnnotationAssertion(rdfs:label "central nervous system myelination") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectAllValuesFrom( )) + +# Class: (myelination in peripheral nervous system) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process in which neuronal axons and dendrites become coated with a segmented lipid-rich sheath (myelin) to enable faster and more energetically efficient conduction of electrical impulses. The sheath is formed by the cell membranes of Schwann cells in the peripheral nervous system. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier.") +AnnotationAssertion( "peripheral nervous system myelination") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0022011") +AnnotationAssertion(rdfs:label "myelination in peripheral nervous system") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (subpallium cell proliferation in forebrain) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The multiplication or reproduction of subpallium cells in the forebrain, resulting in the expansion of a cell population.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0022012") +AnnotationAssertion(rdfs:label "subpallium cell proliferation in forebrain") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (tangential migration from the subventricular zone to the olfactory bulb) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The migration of cells in the telencephalon from the subventricular zone to the olfactory bulb in which cells move orthogonally to the direction of radial migration and do not use radial glial cell processes as substrates for migration.") +AnnotationAssertion( "rostral migratory stream migration") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0022028") +AnnotationAssertion(rdfs:label "tangential migration from the subventricular zone to the olfactory bulb") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (telencephalon cell migration) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The orderly movement of a cell from one site to another at least one of which is located in the telencephalon.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0022029") +AnnotationAssertion(rdfs:label "telencephalon cell migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (telencephalon glial cell migration) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The orderly movement of glial cells through the telencephalon.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0022030") +AnnotationAssertion(rdfs:label "telencephalon glial cell migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (telencephalon astrocyte cell migration) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The orderly movement of an astrocyte cell through the telencephalon.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0022031") +AnnotationAssertion(rdfs:label "telencephalon astrocyte cell migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (telencephalon oligodendrocyte cell migration) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The multiplication or reproduction of telencephalon oligodendrocyte cells, resulting in the expansion of a cell population.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0022032") +AnnotationAssertion(rdfs:label "telencephalon oligodendrocyte cell migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (rhombomere cell migration) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "PMID:15629700") "The movement of a cell within a rhombomere. This process is known to occur as an early step in the generation of anatomical structure from a rhombomere.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0022035") +AnnotationAssertion(rdfs:label "rhombomere cell migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (metencephalon development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process whose specific outcome is the progression of the metencephalon over time, from its formation to the mature structure.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0022037") +AnnotationAssertion(rdfs:label "metencephalon development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (corpus callosum development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:curators") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") "The process whose specific outcome is the progression of the corpus callosum over time, from its formation to the mature structure. The corpus callosum is a thick bundle of nerve fibers comprising a commissural plate connecting the two cerebral hemispheres. It consists of contralateral axon projections that provide communication between the right and left cerebral hemispheres.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0022038") +AnnotationAssertion(rdfs:label "corpus callosum development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cell cycle process) + +AnnotationAssertion(Annotation( "GOC:isa_complete") Annotation( "GOC:mtg_cell_cycle") "The cellular process that ensures successive accurate and complete genome replication and chromosome segregation.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0022402") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "cell cycle process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (molting cycle process) AnnotationAssertion(Annotation( "GOC:isa_complete") "A multicellular organismal process involved in the periodic casting off and regeneration of an outer covering of cuticle, feathers, hair, horns, skin.") @@ -33035,6 +69582,86 @@ AnnotationAssertion(rdfs:label "molt SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (hair cycle process) + +AnnotationAssertion(Annotation( "GOC:isa_complete") "A multicellular organismal process involved in the cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair; one of the collection or mass of filaments growing from the skin of an animal, and forming a covering for a part of the head or for any part or the whole of the body.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0022405") +AnnotationAssertion(rdfs:label "hair cycle process") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (membrane docking) + +AnnotationAssertion(Annotation( "GOC:isa_complete") Annotation( "PMID:27875684") "The initial attachment of a membrane or protein to a target membrane. Docking requires only that the proteins come close enough to interact and adhere.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0022406") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "membrane docking") +SubClassOf( ) + +# Class: (regulation of cell-cell adhesion) + +AnnotationAssertion(Annotation( "GOC:isa_complete") "Any process that modulates the frequency, rate or extent of attachment of a cell to another cell.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0022407") +AnnotationAssertion(rdfs:label "regulation of cell-cell adhesion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (negative regulation of cell-cell adhesion) + +AnnotationAssertion(Annotation( "GOC:isa_complete") "Any process that stops, prevents or reduces the rate or extent of cell adhesion to another cell.") +AnnotationAssertion( "down regulation of cell-cell adhesion") +AnnotationAssertion( "down-regulation of cell-cell adhesion") +AnnotationAssertion( "downregulation of cell-cell adhesion") +AnnotationAssertion( "inhibition of cell-cell adhesion") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0022408") +AnnotationAssertion(rdfs:label "negative regulation of cell-cell adhesion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of cell-cell adhesion) + +AnnotationAssertion(Annotation( "GOC:isa_complete") "Any process that activates or increases the rate or extent of cell adhesion to another cell.") +AnnotationAssertion( "up regulation of cell-cell adhesion") +AnnotationAssertion( "up-regulation of cell-cell adhesion") +AnnotationAssertion( "upregulation of cell-cell adhesion") +AnnotationAssertion( "activation of cell-cell adhesion") +AnnotationAssertion( "stimulation of cell-cell adhesion") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0022409") +AnnotationAssertion(rdfs:label "positive regulation of cell-cell adhesion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (circadian sleep/wake cycle process) + +AnnotationAssertion(Annotation( "GOC:isa_complete") "A behavioral process involved in the cycle from wakefulness through an orderly succession of sleep states and stages that occurs on an approximately 24 hour rhythm.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0022410") +AnnotationAssertion(rdfs:label "circadian sleep/wake cycle process") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cellular component disassembly) + +AnnotationAssertion(Annotation( "GOC:isa_complete") "A cellular process that results in the breakdown of a cellular component.") +AnnotationAssertion( "GO:0071845") +AnnotationAssertion( "cell structure disassembly") +AnnotationAssertion( "cellular component disassembly at cellular level") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0022411") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "cellular component disassembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +DisjointClasses( ) + # Class: (cellular process involved in reproduction in multicellular organism) AnnotationAssertion(Annotation( "GOC:isa_complete") "A process, occurring at the cellular level, that is involved in the reproductive function of a multicellular organism.") @@ -33042,6 +69669,7 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0022412") AnnotationAssertion(rdfs:label "cellular process involved in reproduction in multicellular organism") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) @@ -33056,6 +69684,7 @@ AnnotationAssertion( "GO:0022414") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "reproductive process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) DisjointClasses( ) # Class: (digestive system process) @@ -33065,6 +69694,7 @@ AnnotationAssertion( "GO:0022600") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "digestive system process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) # Class: (ovulation cycle process) @@ -33081,6 +69711,64 @@ SubClassOf( ObjectSomeValuesFrom( ObjectSomeValuesFrom( )) SubClassOf( ObjectAllValuesFrom( )) +# Class: (regulation of anatomical structure morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of anatomical structure morphogenesis.") +AnnotationAssertion( "regulation of morphogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0022603") +AnnotationAssertion(rdfs:label "regulation of anatomical structure morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of cell morphogenesis) + +AnnotationAssertion(Annotation( "GOC:isa_complete") "Any process that modulates the frequency, rate or extent of cell morphogenesis. Cell morphogenesis is the developmental process in which the shape of a cell is generated and organized.") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "negative regulation of cell shape and cell size") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "positive regulation of cell shape and cell size") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "regulation of cell shape and cell size") +AnnotationAssertion( "GO:0022604") +AnnotationAssertion(rdfs:label "regulation of cell morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (mammalian oogenesis stage) + +AnnotationAssertion(Annotation( "GOC:isa_complete") Annotation( "GOC:mtg_sensu") "A reproductive process that is a step in the formation and maturation of an ovum or female gamete from a primordial female germ cell.") +AnnotationAssertion( "mammalian oogenesis process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0022605") +AnnotationAssertion(rdfs:label "mammalian oogenesis stage") +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cellular component assembly) + +AnnotationAssertion(Annotation( "GOC:isa_complete") "The aggregation, arrangement and bonding together of a cellular component.") +AnnotationAssertion( "GO:0071844") +AnnotationAssertion( "cell structure assembly") +AnnotationAssertion( "cellular component assembly at cellular level") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0022607") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "cellular component assembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (gland morphogenesis) + +AnnotationAssertion(Annotation( "GOC:isa_complete") "The process in which the anatomical structures of a gland are generated and organized.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0022612") +AnnotationAssertion(rdfs:label "gland morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (ribonucleoprotein complex biogenesis) AnnotationAssertion(Annotation( "GOC:isa_complete") Annotation( "GOC:mah") "A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a complex containing RNA and proteins. Includes the biosynthesis of the constituent RNA and protein molecules, and those macromolecular modifications that are involved in synthesis or assembly of the ribonucleoprotein complex.") @@ -33091,6 +69779,15 @@ AnnotationAssertion( "ribonucleoprotein complex biogenesis") SubClassOf( ) +# Class: (extracellular matrix disassembly) + +AnnotationAssertion(Annotation( "GOC:jid") "A process that results in the breakdown of the extracellular matrix.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0022617") +AnnotationAssertion(rdfs:label "extracellular matrix disassembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + # Class: (protein-RNA complex assembly) AnnotationAssertion(Annotation( "GOC:jl") "The aggregation, arrangement and bonding together of proteins and RNA molecules to form a ribonucleoprotein complex.") @@ -33101,6 +69798,7 @@ AnnotationAssertion( "GO:0022618") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "protein-RNA complex assembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) @@ -33152,6 +69850,7 @@ AnnotationAssertion( "GO:0022892") AnnotationAssertion(Annotation(rdfs:label "Egress of internalized antigen to the cytosol via sec61") "Reactome:R-HSA-1236947") AnnotationAssertion(Annotation(rdfs:label "SLC2A9 transports Fru, Glc, urate") "Reactome:R-HSA-429036") +AnnotationAssertion(Annotation(rdfs:label "MATEs mediate extrusion of xenobiotics") "Reactome:R-HSA-434650") AnnotationAssertion(Annotation(rdfs:label "Defective SLC2A9 does not transport Fru, Glc, urate") "Reactome:R-HSA-5638209") AnnotationAssertion(Annotation(rdfs:label "Fe3+ dissociates from SLC22A17:LCN2:2,5DHBA") "Reactome:R-HSA-5671707") AnnotationAssertion(Annotation(rdfs:label "An unknown carrier transports cytosolic glyoxylate to the peroxisome") "Reactome:R-HSA-6784434") @@ -33241,6 +69940,7 @@ AnnotationAssertion(Annotation( "GOC:mah") "regulation of signalling process") AnnotationAssertion( "GO:0023051") AnnotationAssertion(rdfs:label "regulation of signaling") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (signaling) @@ -33268,6 +69968,34 @@ AnnotationAssertion(rdfs:label "sign SubClassOf( ) DisjointClasses( ) +# Class: (positive regulation of signaling) + +AnnotationAssertion(Annotation( "GOC:mtg_signal") "Any process that activates, maintains or increases the frequency, rate or extent of a signaling process.") +AnnotationAssertion( "2010-02-16T09:30:50Z") +AnnotationAssertion(Annotation( "GOC:mah") "positive regulation of signalling process") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:bf") "positive regulation of signaling process") +AnnotationAssertion( "GO:0023056") +AnnotationAssertion(rdfs:label "positive regulation of signaling") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (negative regulation of signaling) + +AnnotationAssertion(Annotation( "GOC:mtg_signal") "Any process that stops, prevents, or reduces the frequency, rate or extent of a signaling process.") +AnnotationAssertion( "2010-02-16T09:30:50Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:bf") "negative regulation of signaling process") +AnnotationAssertion(Annotation( "GOC:mah") "negative regulation of signalling process") +AnnotationAssertion( "GO:0023057") +AnnotationAssertion(rdfs:label "negative regulation of signaling") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (signal release) AnnotationAssertion(Annotation( "GOC:mtg_signal") "The process in which a signal is secreted or discharged into the extracellular medium from a cellular source.") @@ -33276,8 +70004,49 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:0023061") AnnotationAssertion(rdfs:label "signal release") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (metal ion transport) + +AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of metal ions, any metal ion with an electric charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/23033"^^xsd:anyURI) +AnnotationAssertion( "mah") +AnnotationAssertion( "2009-07-31T01:07:46Z") +AnnotationAssertion( "GO:0070838") +AnnotationAssertion( "GO:0070839") +AnnotationAssertion( "divalent metal ion export") +AnnotationAssertion( "divalent metal ion transport") +AnnotationAssertion( "heavy metal ion transport") +AnnotationAssertion( "metal ion export") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0030001") +AnnotationAssertion(rdfs:label "metal ion transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (intracellular monoatomic cation homeostasis) + +AnnotationAssertion(Annotation( "GOC:ceb") Annotation( "GOC:mah") "A homeostatic process involved in the maintenance of a steady state level of monoatomic cations within a cell. Monatomic cations (also called simple cations) are cations consisting of exactly one atom.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/24455"^^xsd:anyURI) +AnnotationAssertion( "cellular cation homeostasis") +AnnotationAssertion( "cellular monoatomic cation homeostasis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0030003") +AnnotationAssertion(rdfs:label "intracellular monoatomic cation homeostasis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (establishment of cell polarity) + +AnnotationAssertion(Annotation( "GOC:mah") "The specification and formation of anisotropic intracellular organization or cell growth patterns.") +AnnotationAssertion( "GO:0000283") +AnnotationAssertion( "GO:0030468") +AnnotationAssertion( "cell polarization") +AnnotationAssertion( "bud site selection/establishment of cell polarity") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0030010") +AnnotationAssertion(rdfs:label "establishment of cell polarity") +SubClassOf( ) + # Class: (myofibril) AnnotationAssertion(Annotation( "ISBN:0815316194") "The contractile element of skeletal and cardiac muscle; a long, highly organized bundle of actin, myosin, and other proteins that contracts by a sliding filament mechanism.") @@ -33285,8 +70054,98 @@ AnnotationAssertion( "cellular_component") AnnotationAssertion( "GO:0030016") AnnotationAssertion(rdfs:label "myofibril") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (sarcomere) + +AnnotationAssertion(Annotation( "ISBN:0815316194") "The repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs.") +AnnotationAssertion( "Wikipedia:Sarcomere") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0030017") +AnnotationAssertion(rdfs:label "sarcomere") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (actin filament-based process) + +AnnotationAssertion(Annotation( "GOC:mah") "Any cellular process that depends upon or alters the actin cytoskeleton, that part of the cytoskeleton comprising actin filaments and their associated proteins.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "microfilament-based process") +AnnotationAssertion( "GO:0030029") +AnnotationAssertion(rdfs:label "actin filament-based process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (cell projection organization) + +AnnotationAssertion(Annotation( "GOC:jl") Annotation( "GOC:mah") Annotation( "http://www.cogsci.princeton.edu/~wn/") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon.") +AnnotationAssertion( "cell projection organisation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:mah") "cell projection organization and biogenesis") +AnnotationAssertion(Annotation( "GOC:mah") "cell surface structure organization and biogenesis") +AnnotationAssertion( "GO:0030030") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "cell projection organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (cell projection assembly) + +AnnotationAssertion(Annotation( "GOC:jl") Annotation( "GOC:mah") Annotation( "http://www.cogsci.princeton.edu/~wn/") "Formation of a prolongation or process extending from a cell, e.g. a flagellum or axon.") +AnnotationAssertion( "formation of a cell surface projection") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:mah") "cell projection biogenesis") +AnnotationAssertion( "GO:0030031") +AnnotationAssertion(rdfs:label "cell projection assembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (microvillus assembly) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "ISBN:0815316194") "Formation of a microvillus, a thin cylindrical membrane-covered projection on the surface of a cell.") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:mah") "microvillus biogenesis") +AnnotationAssertion( "GO:0030033") +AnnotationAssertion(rdfs:label "microvillus assembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (actin cytoskeleton organization) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:jl") Annotation( "GOC:mah") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/23114"^^xsd:anyURI) +AnnotationAssertion( "actin cytoskeleton organisation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:mah") "actin cytoskeleton organization and biogenesis") +AnnotationAssertion( "actin modulating activity") +AnnotationAssertion( "GO:0030036") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "actin cytoskeleton organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (actin filament-based movement) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mah") "Movement of organelles or other particles along actin filaments, or sliding of actin filaments past each other, mediated by motor proteins.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/19809"^^xsd:anyURI) +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0030048") +AnnotationAssertion(rdfs:label "actin filament-based movement") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (vesicle transport along actin filament) + +AnnotationAssertion(Annotation( "GOC:mah") "Movement of a vesicle along an actin filament, mediated by motor proteins.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0030050") +AnnotationAssertion(rdfs:label "vesicle transport along actin filament") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + # Class: (cell junction) AnnotationAssertion(Annotation( "GOC:aruk") Annotation( "GOC:bc") Annotation( "GOC:mah") Annotation( "ISBN:0198506732") Annotation( "PMID:26820516") Annotation( "PMID:28096264") Annotation( "http://www.vivo.colostate.edu/hbooks/cmb/cells/pmemb/junctions_a.html") "A cellular component that forms a specialized region of connection between two or more cells, or between a cell and the extracellular matrix, or between two membrane-bound components of a cell, such as flagella.") @@ -33303,12 +70162,23 @@ SubClassOf( ObjectComplementOf(Object SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) DisjointClasses( ObjectSomeValuesFrom( )) +# Class: (insulin processing) + +AnnotationAssertion(Annotation( "ISBN:0198506732") "The formation of mature insulin by proteolysis of the precursor preproinsulin. The signal sequence is first cleaved from preproinsulin to form proinsulin; proinsulin is then cleaved to release the C peptide, leaving the A and B chains of mature insulin linked by disulfide bridges.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0030070") +AnnotationAssertion(rdfs:label "insulin processing") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + # Class: (peptide hormone secretion) AnnotationAssertion(Annotation( "GOC:mah") "The regulated release of a peptide hormone from a cell.") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0030072") AnnotationAssertion(rdfs:label "peptide hormone secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) @@ -33319,6 +70189,7 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0030073") AnnotationAssertion(rdfs:label "insulin secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) @@ -33336,6 +70207,7 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0030097") AnnotationAssertion(rdfs:label "hemopoiesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (lymphocyte differentiation) @@ -33348,17 +70220,53 @@ AnnotationAssertion(Annotation( "GO:0030098") AnnotationAssertion(rdfs:comment "Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.") AnnotationAssertion(rdfs:label "lymphocyte differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) +# Class: (myeloid cell differentiation) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") "The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of any cell of the myeloid leukocyte, megakaryocyte, thrombocyte, or erythrocyte lineages.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0030099") +AnnotationAssertion(rdfs:label "myeloid cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (regulation of endocytosis) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of endocytosis.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0030100") +AnnotationAssertion(rdfs:label "regulation of endocytosis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + # Class: (vasopressin secretion) AnnotationAssertion(Annotation( "GOC:mah") "The regulated release of vasopressin from secretory granules into the blood.") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0030103") AnnotationAssertion(rdfs:label "vasopressin secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (transport vesicle) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "PMID:22160157") "Any of the vesicles of the constitutive secretory pathway, which carry cargo from the endoplasmic reticulum to the Golgi, between Golgi cisternae, from the Golgi to the ER (retrograde transport) or to destinations within or outside the cell.") +AnnotationAssertion( "NIF_Subcellular:sao885490876") +AnnotationAssertion( "constitutive secretory pathway transport vesicle") +AnnotationAssertion( "Golgi to vacuole transport vesicle") +AnnotationAssertion( "Golgi-vacuole transport vesicle") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "secretory vesicle") +AnnotationAssertion( "GO:0030133") +AnnotationAssertion(rdfs:comment "Note that the term 'secretory vesicle' is sometimes used in this sense, but can also mean 'secretory granule ; GO:0030141'.") +AnnotationAssertion(rdfs:label "transport vesicle") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (secretory granule) AnnotationAssertion(Annotation( "GOC:mah") Annotation( "ISBN:0198506732") "A small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion. Secretory granules move towards the periphery of the cell and upon stimulation, their membranes fuse with the cell membrane, and their protein load is exteriorized. Processing of the contained protein may take place in secretory granules.") @@ -33375,6 +70283,32 @@ SubClassOf( ObjectSomeValuesFrom( ObjectSomeValuesFrom( )) DisjointClasses( ObjectSomeValuesFrom( )) +# Class: (sphingolipid biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).") +AnnotationAssertion( "MetaCyc:PWY-5129") +AnnotationAssertion( "sphingolipid anabolism") +AnnotationAssertion( "sphingolipid biosynthesis") +AnnotationAssertion( "sphingolipid formation") +AnnotationAssertion( "sphingolipid synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0030148") +AnnotationAssertion(rdfs:label "sphingolipid biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (sphingolipid catabolic process) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).") +AnnotationAssertion( "sphingolipid breakdown") +AnnotationAssertion( "sphingolipid catabolism") +AnnotationAssertion( "sphingolipid degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0030149") +AnnotationAssertion(rdfs:label "sphingolipid catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + # Class: (cell differentiation) AnnotationAssertion(Annotation( "ISBN:0198506732") "The cellular developmental process in which a relatively unspecialized cell, e.g. embryonic or regenerative cell, acquires specialized structural and/or functional features that characterize a specific cell. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.") @@ -33389,8 +70323,100 @@ AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (regulation of cell adhesion) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of attachment of a cell to another cell or to the extracellular matrix.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "cell adhesion receptor regulator activity") +AnnotationAssertion( "GO:0030155") +AnnotationAssertion(rdfs:label "regulation of cell adhesion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of proteolysis) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein.") +AnnotationAssertion( "regulation of peptidolysis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0030162") +AnnotationAssertion(rdfs:label "regulation of proteolysis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (protein catabolic process) + +AnnotationAssertion(Annotation( "GOC:mah") "The chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/23112"^^xsd:anyURI) +AnnotationAssertion( "GO:0044254") +AnnotationAssertion( "GO:0044257") +AnnotationAssertion( "Wikipedia:Protein_catabolism") +AnnotationAssertion( "cellular protein breakdown") +AnnotationAssertion( "cellular protein catabolic process") +AnnotationAssertion( "cellular protein catabolism") +AnnotationAssertion( "cellular protein degradation") +AnnotationAssertion( "protein breakdown") +AnnotationAssertion( "protein catabolism") +AnnotationAssertion( "protein degradation") +AnnotationAssertion( "multicellular organismal protein catabolic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "pheromone catabolic process") +AnnotationAssertion( "pheromone catabolism") +AnnotationAssertion( "GO:0030163") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:comment "This term refers to the breakdown of mature proteins. For cleavage events involved in generating a mature protein from a precursor, consider instead the term 'protein maturation ; GO:0051604' and its children.") +AnnotationAssertion(rdfs:label "protein catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (proteoglycan biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans.") +AnnotationAssertion( "proteoglycan anabolism") +AnnotationAssertion( "proteoglycan biosynthesis") +AnnotationAssertion( "proteoglycan formation") +AnnotationAssertion( "proteoglycan synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0030166") +AnnotationAssertion(rdfs:label "proteoglycan biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (proteoglycan catabolic process) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans.") +AnnotationAssertion( "proteoglycan breakdown") +AnnotationAssertion( "proteoglycan catabolism") +AnnotationAssertion( "proteoglycan degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0030167") +AnnotationAssertion(rdfs:label "proteoglycan catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (platelet activation) + +AnnotationAssertion(Annotation( "http://www.graylab.ac.uk/omd/") "A series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue. These events include shape change, adhesiveness, aggregation, and release reactions. When carried through to completion, these events lead to the formation of a stable hemostatic plug.") +AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:pde") "blood coagulation, platelet activation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0030168") +AnnotationAssertion(rdfs:label "platelet activation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (neuron differentiation) + +AnnotationAssertion(Annotation( "GOC:mah") "The process in which a relatively unspecialized cell acquires specialized features of a neuron.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0030182") +AnnotationAssertion(rdfs:label "neuron differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (B cell differentiation) AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GO_REF:0000022") "The process in which a precursor cell type acquires the specialized features of a B cell. A B cell is a lymphocyte of B lineage with the phenotype CD19-positive and capable of B cell mediated immunity.") @@ -33403,6 +70429,7 @@ AnnotationAssertion(Annotation( "GO:0030183") AnnotationAssertion(rdfs:comment "Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.") AnnotationAssertion(rdfs:label "B cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) @@ -33413,6 +70440,7 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0030186") AnnotationAssertion(rdfs:label "melatonin metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ) @@ -33427,11 +70455,57 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0030187") AnnotationAssertion(rdfs:label "melatonin biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) +# Class: (regulation of blood coagulation) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of blood coagulation.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0030193") +AnnotationAssertion(rdfs:label "regulation of blood coagulation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of blood coagulation) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of blood coagulation.") +AnnotationAssertion( "up regulation of blood coagulation") +AnnotationAssertion( "up-regulation of blood coagulation") +AnnotationAssertion( "upregulation of blood coagulation") +AnnotationAssertion( "activation of blood coagulation") +AnnotationAssertion( "stimulation of blood coagulation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0030194") +AnnotationAssertion(rdfs:label "positive regulation of blood coagulation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of blood coagulation) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of blood coagulation.") +AnnotationAssertion( "down regulation of blood coagulation") +AnnotationAssertion( "down-regulation of blood coagulation") +AnnotationAssertion( "downregulation of blood coagulation") +AnnotationAssertion( "inhibition of blood coagulation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0030195") +AnnotationAssertion(rdfs:label "negative regulation of blood coagulation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + # Class: (extracellular matrix organization) AnnotationAssertion(Annotation( "GOC:mah") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix.") @@ -33443,8 +70517,105 @@ AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "extracellular matrix organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (collagen fibril organization) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "ISBN:0815316194") "Any process that determines the size and arrangement of collagen fibrils within an extracellular matrix.") +AnnotationAssertion( ) +AnnotationAssertion( "collagen fibril organisation") +AnnotationAssertion(Annotation( "GOC:mah") "fibrillar collagen organization") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0030199") +AnnotationAssertion(rdfs:label "collagen fibril organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses( ObjectSomeValuesFrom( )) + +# Class: (glycosaminoglycan metabolic process) + +AnnotationAssertion(Annotation( "ISBN:0192800981") "The chemical reactions and pathways involving glycosaminoglycans, any of a group of polysaccharides that contain amino sugars.") +AnnotationAssertion( "glycosaminoglycan metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0030203") +AnnotationAssertion(rdfs:label "glycosaminoglycan metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (chondroitin sulfate metabolic process) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving chondroitin sulfate, any member of a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues, the repeat units of which consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate. They usually occur linked to a protein to form proteoglycans. Two subgroups exist, one in which the sulfate is on the 4-position (chondroitin sulfate A) and the second in which it is in the 6-position (chondroitin sulfate C). They often are polydisperse and often differ in the degree of sulfation from tissue to tissue. The chains of repeating disaccharide are covalently linked to the side chains of serine residues in the polypeptide backbone of a protein by a glycosidic attachment through the trisaccharide unit galactosyl-galactosyl-xylosyl. Chondroitin sulfate B is more usually known as dermatan sulfate.") +AnnotationAssertion( "chondroitin sulfate metabolism") +AnnotationAssertion( "chondroitin sulphate metabolic process") +AnnotationAssertion( "chondroitin sulphate metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0030204") +AnnotationAssertion(rdfs:label "chondroitin sulfate metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (chondroitin sulfate biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of chondroitin sulfate, any member of a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues, the repeat units of which consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate.") +AnnotationAssertion( "chondroitin sulfate anabolism") +AnnotationAssertion( "chondroitin sulfate biosynthesis") +AnnotationAssertion( "chondroitin sulfate formation") +AnnotationAssertion( "chondroitin sulfate synthesis") +AnnotationAssertion( "chondroitin sulphate biosynthesis") +AnnotationAssertion( "chondroitin sulphate biosynthetic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0030206") +AnnotationAssertion(rdfs:label "chondroitin sulfate biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (chondroitin sulfate catabolic process) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of chondroitin sulfate, any member of a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues, the repeat units of which consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate.") +AnnotationAssertion( "chondroitin sulfate breakdown") +AnnotationAssertion( "chondroitin sulfate catabolism") +AnnotationAssertion( "chondroitin sulfate degradation") +AnnotationAssertion( "chondroitin sulphate catabolic process") +AnnotationAssertion( "chondroitin sulphate catabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0030207") +AnnotationAssertion(rdfs:label "chondroitin sulfate catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (hyaluronan metabolic process) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving hyaluronan, the naturally occurring anionic form of hyaluronic acid, any member of a group of glycosaminoglycans, the repeat units of which consist of beta-1,4 linked D-glucuronyl-beta-(1,3)-N-acetyl-D-glucosamine.") +AnnotationAssertion( "hyaluronan metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0030212") +AnnotationAssertion(rdfs:label "hyaluronan metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (hyaluronan biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of hyaluronan, the naturally occurring anionic form of hyaluronic acid, any member of a group of glycosaminoglycans, the repeat units of which consist of beta-1,4 linked D-glucuronyl-beta-(1,3)-N-acetyl-D-glucosamine.") +AnnotationAssertion( "hyaluronan anabolism") +AnnotationAssertion( "hyaluronan biosynthesis") +AnnotationAssertion( "hyaluronan formation") +AnnotationAssertion( "hyaluronan synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0030213") +AnnotationAssertion(rdfs:label "hyaluronan biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (hyaluronan catabolic process) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of hyaluronan, the naturally occurring anionic form of hyaluronic acid, any member of a group of glycosaminoglycans, the repeat units of which consist of beta-1,4 linked D-glucuronyl-beta-(1,3)-N-acetyl-D-glucosamine.") +AnnotationAssertion( "hyaluronan breakdown") +AnnotationAssertion( "hyaluronan catabolism") +AnnotationAssertion( "hyaluronan degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0030214") +AnnotationAssertion(rdfs:label "hyaluronan catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (keratinocyte differentiation) AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mah") Annotation( "GOC:sdb_2009") Annotation( "GOC:tb") "The process in which a relatively unspecialized cell acquires specialized features of a keratinocyte.") @@ -33452,6 +70623,7 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0030216") AnnotationAssertion(rdfs:label "keratinocyte differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) @@ -33468,9 +70640,239 @@ AnnotationAssertion(Annotation( "GO:0030217") AnnotationAssertion(rdfs:comment "Note that the term 'thymocyte differentiation' was merged into this term because thymocytes are T cells, and thus the term was essentially redundant. Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.") AnnotationAssertion(rdfs:label "T cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) +# Class: (erythrocyte differentiation) + +AnnotationAssertion(Annotation( "GOC:mah") "The process in which a myeloid precursor cell acquires specializes features of an erythrocyte.") +AnnotationAssertion( "Wikipedia:Erythropoiesis") +AnnotationAssertion(Annotation( "CL:0000232") "RBC differentiation") +AnnotationAssertion( "erythrocyte cell differentiation") +AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:dph") "erythropoiesis") +AnnotationAssertion(Annotation( "CL:0000232") "red blood cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0030218") +AnnotationAssertion(rdfs:label "erythrocyte differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (megakaryocyte differentiation) + +AnnotationAssertion(Annotation( "GOC:mah") "The process in which a myeloid precursor cell acquires specializes features of a megakaryocyte.") +AnnotationAssertion( "megakaryocyte cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0030219") +AnnotationAssertion(rdfs:label "megakaryocyte differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (platelet formation) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "ISBN:0815316194") "The process in which platelets bud from long processes extended by megakaryocytes.") +AnnotationAssertion(Annotation( "GOC:curators") Annotation( ) "platelet extrusion") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0030220") +AnnotationAssertion(rdfs:label "platelet formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (neutrophil differentiation) + +AnnotationAssertion(Annotation( "GOC:mah") "The process in which a myeloid precursor cell acquires the specialized features of a neutrophil.") +AnnotationAssertion( "neutrophil cell differentiation") +AnnotationAssertion(Annotation( "GOC:yaf") "neutrophil granulocyte differentiation") +AnnotationAssertion(Annotation( "GOC:yaf") "neutrophil granulocytopoiesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0030223") +AnnotationAssertion(rdfs:label "neutrophil differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (monocyte differentiation) + +AnnotationAssertion(Annotation( "GOC:mah") "The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a monocyte.") +AnnotationAssertion( "monocyte cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0030224") +AnnotationAssertion(rdfs:label "monocyte differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (macrophage differentiation) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") "The process in which a relatively unspecialized monocyte acquires the specialized features of a macrophage.") +AnnotationAssertion( "macrophage cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0030225") +AnnotationAssertion(rdfs:label "macrophage differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (myofibril assembly) + +AnnotationAssertion(Annotation( "GOC:mah") "Formation of myofibrils, the repeating units of striated muscle.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0030239") +AnnotationAssertion(rdfs:label "myofibril assembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cellulose metabolic process) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation.") +AnnotationAssertion( "GO:0016177") +AnnotationAssertion( "cellulose metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0030243") +AnnotationAssertion(rdfs:label "cellulose metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (cellulose biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation.") +AnnotationAssertion( "GO:0016178") +AnnotationAssertion( "MetaCyc:PWY-1001") +AnnotationAssertion( "cellulose anabolism") +AnnotationAssertion( "cellulose biosynthesis") +AnnotationAssertion( "cellulose formation") +AnnotationAssertion( "cellulose synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0030244") +AnnotationAssertion(rdfs:label "cellulose biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (cellulose catabolic process) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation.") +AnnotationAssertion( "GO:0016179") +AnnotationAssertion( "cellulose breakdown") +AnnotationAssertion( "cellulose catabolism") +AnnotationAssertion( "cellulose degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0030245") +AnnotationAssertion(rdfs:label "cellulose catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (carbohydrate binding) + +AnnotationAssertion(Annotation( "GOC:mah") "Binding to a carbohydrate, which includes monosaccharides, oligosaccharides and polysaccharides as well as substances derived from monosaccharides by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom. Cyclitols are generally not regarded as carbohydrates.") +AnnotationAssertion( "GO:0005529") +AnnotationAssertion( "sugar binding") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "selectin") +AnnotationAssertion( "GO:0030246") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "carbohydrate binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (polysaccharide binding) + +AnnotationAssertion(Annotation( "GOC:mah") "Binding to a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically.") +AnnotationAssertion( "GO:0002506") +AnnotationAssertion( "polysaccharide assembly with MHC class II protein complex") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0030247") +AnnotationAssertion(rdfs:label "polysaccharide binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (cellulose binding) + +AnnotationAssertion(Annotation( "GOC:mah") "Binding to cellulose.") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0030248") +AnnotationAssertion(rdfs:label "cellulose binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (growth hormone secretion) + +AnnotationAssertion(Annotation( "GOC:mah") "The regulated release of growth hormone from secretory granules into the blood.") +AnnotationAssertion(Annotation( "GOC:mah") "somatotropin secretion") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0030252") +AnnotationAssertion(rdfs:label "growth hormone secretion") +SubClassOf( ) + +# Class: (chromosome condensation) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "ISBN:0815316194") "The progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis, in eukaryotic cells.") +AnnotationAssertion( "GO:0000068") +AnnotationAssertion(Annotation( "Wikipedia:DNA_condensation") "DNA condensation") +AnnotationAssertion(Annotation( "GOC:bf") "eukaryotic chromosome condensation") +AnnotationAssertion(Annotation( "GOC:bf") "nuclear chromosome condensation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0030261") +AnnotationAssertion(rdfs:label "chromosome condensation") +SubClassOf( ) + +# Class: (apoptotic nuclear changes) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:mtg_apoptosis") "Alterations undergone by nuclei at the molecular and morphological level as part of the execution phase of apoptosis.") +AnnotationAssertion( "apoptotic nuclear change") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0030262") +AnnotationAssertion(rdfs:label "apoptotic nuclear changes") +SubClassOf( ) + +# Class: (apoptotic chromosome condensation) + +AnnotationAssertion(Annotation( "GOC:mah") "The compaction of chromatin during apoptosis.") +AnnotationAssertion( "Wikipedia:Pyknosis") +AnnotationAssertion( "pyknosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0030263") +AnnotationAssertion(rdfs:label "apoptotic chromosome condensation") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (nuclear fragmentation involved in apoptotic nuclear change) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mah") Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:tb") Annotation( "ISBN:0721639976") "The breakdown of the nucleus into small membrane-bounded compartments, or blebs, each of which contain compacted DNA.") +AnnotationAssertion( "apoptotic nuclear fragmentation") +AnnotationAssertion( "nucleus fragmentation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "nuclear fragmentation during apoptosis") +AnnotationAssertion( "GO:0030264") +AnnotationAssertion(rdfs:label "nuclear fragmentation involved in apoptotic nuclear change") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of ossification) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance.") +AnnotationAssertion( "regulation of bone biosynthesis") +AnnotationAssertion( "regulation of bone formation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0030278") +AnnotationAssertion(rdfs:label "regulation of ossification") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of ossification) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance.") +AnnotationAssertion( "down regulation of ossification") +AnnotationAssertion( "down-regulation of ossification") +AnnotationAssertion( "downregulation of ossification") +AnnotationAssertion( "negative regulation of bone biosynthesis") +AnnotationAssertion( "negative regulation of bone formation") +AnnotationAssertion( "inhibition of ossification") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0030279") +AnnotationAssertion(rdfs:label "negative regulation of ossification") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + # Class: (bone mineralization) AnnotationAssertion(Annotation( "GOC:mah") Annotation( "PMID:22936354") "The deposition of hydroxyapatite, a form of calcium phosphate with the formula Ca10(PO4)6(OH)2, in bone tissue.") @@ -33478,9 +70880,41 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0030282") AnnotationAssertion(rdfs:label "bone mineralization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (positive regulation of cell growth) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate, extent or direction of cell growth.") +AnnotationAssertion( "up regulation of cell growth") +AnnotationAssertion( "up-regulation of cell growth") +AnnotationAssertion( "upregulation of cell growth") +AnnotationAssertion( "activation of cell growth") +AnnotationAssertion( "stimulation of cell growth") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0030307") +AnnotationAssertion(rdfs:label "positive regulation of cell growth") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of cell growth) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate, extent or direction of cell growth.") +AnnotationAssertion( "down regulation of cell growth") +AnnotationAssertion( "down-regulation of cell growth") +AnnotationAssertion( "downregulation of cell growth") +AnnotationAssertion( "inhibition of cell growth") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0030308") +AnnotationAssertion(rdfs:label "negative regulation of cell growth") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + # Class: (external encapsulating structure) AnnotationAssertion(Annotation( "GOC:go_curators") "A structure that lies outside the plasma membrane and surrounds the entire cell or cells. This does not include the periplasmic space.") @@ -33497,6 +70931,129 @@ SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (osteoclast differentiation) + +AnnotationAssertion(Annotation( "CL:0000092") Annotation( "GOC:add") Annotation( "ISBN:0781735149") Annotation( "PMID:12161749") "The process in which a relatively unspecialized monocyte acquires the specialized features of an osteoclast. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue.") +AnnotationAssertion( "osteoclast cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0030316") +AnnotationAssertion(rdfs:label "osteoclast differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (flagellated sperm motility) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:cilia") Annotation( "GOC:krc") Annotation( "GO_REF:0000060") Annotation( "PMID:26680031") "The directed, self-propelled movement of a cilium (aka flagellum) that contributes to the movement of a flagellated sperm.") +AnnotationAssertion( "GO:0097724") +AnnotationAssertion( "GO:1905419") +AnnotationAssertion( "sperm motility") +AnnotationAssertion( "sperm movement") +AnnotationAssertion( "Wikipedia:Sperm_motility") +AnnotationAssertion( "flagellated sperm movement") +AnnotationAssertion(Annotation( "GOC:cilia") Annotation( "GOC:krc") "sperm flagellum movement") +AnnotationAssertion( "sperm flagellum movement involved in flagellated sperm motility") +AnnotationAssertion(Annotation( "GOC:TermGenie") "sperm flagellum movement involved in flagellated sperm movement") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0030317") +AnnotationAssertion(rdfs:label "flagellated sperm motility") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (melanocyte differentiation) + +AnnotationAssertion(Annotation( "GOC:mah") "The process in which a relatively unspecialized cell acquires specialized features of a melanocyte.") +AnnotationAssertion( "melanocyte cell differentiation") +AnnotationAssertion( "melanophore differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0030318") +AnnotationAssertion(rdfs:label "melanocyte differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (respiratory tube development) + +AnnotationAssertion(Annotation( "GOC:jid") "The process whose specific outcome is the progression of the respiratory tube over time, from its formation to the mature structure. The respiratory tube is assumed to mean any tube in the respiratory tract.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0030323") +AnnotationAssertion(rdfs:label "respiratory tube development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (lung development) + +AnnotationAssertion(Annotation( "GOC:jid") Annotation( "UBERON:0002048") "The process whose specific outcome is the progression of the lung over time, from its formation to the mature structure. In all air-breathing vertebrates the lungs are developed from the ventral wall of the oesophagus as a pouch which divides into two sacs. In amphibians and many reptiles the lungs retain very nearly this primitive sac-like character, but in the higher forms the connection with the esophagus becomes elongated into the windpipe and the inner walls of the sacs become more and more divided, until, in the mammals, the air spaces become minutely divided into tubes ending in small air cells, in the walls of which the blood circulates in a fine network of capillaries. In mammals the lungs are more or less divided into lobes, and each lung occupies a separate cavity in the thorax.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0030324") +AnnotationAssertion(rdfs:label "lung development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (adrenal gland development) + +AnnotationAssertion(Annotation( "GOC:dgh") "The process whose specific outcome is the progression of the adrenal gland over time, from its formation to the mature structure. This gland can either be a discrete structure located bilaterally above each kidney, or a cluster of cells in the head kidney that perform the functions of the adrenal gland. In either case, this organ consists of two cells types, aminergic chromaffin cells and steroidogenic cortical cells.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "interrenal gland") +AnnotationAssertion( "GO:0030325") +AnnotationAssertion(rdfs:label "adrenal gland development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (regulation of cell migration) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of cell migration.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0030334") +AnnotationAssertion(rdfs:label "regulation of cell migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (positive regulation of cell migration) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of cell migration.") +AnnotationAssertion( "up regulation of cell migration") +AnnotationAssertion( "up-regulation of cell migration") +AnnotationAssertion( "upregulation of cell migration") +AnnotationAssertion( "activation of cell migration") +AnnotationAssertion( "stimulation of cell migration") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0030335") +AnnotationAssertion(rdfs:label "positive regulation of cell migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of cell migration) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of cell migration.") +AnnotationAssertion( "down regulation of cell migration") +AnnotationAssertion( "down-regulation of cell migration") +AnnotationAssertion( "downregulation of cell migration") +AnnotationAssertion( "inhibition of cell migration") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0030336") +AnnotationAssertion(rdfs:label "negative regulation of cell migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (membrane disassembly) + +AnnotationAssertion(Annotation( "GOC:mah") "The controlled breakdown of any cell membrane in the context of a normal process such as autophagy.") +AnnotationAssertion( "membrane breakdown") +AnnotationAssertion( "membrane catabolism") +AnnotationAssertion( "membrane degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0030397") +AnnotationAssertion(rdfs:label "membrane disassembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + # Class: (defecation) AnnotationAssertion(Annotation( "GOC:mah") "The expulsion of feces from the rectum.") @@ -33530,6 +71087,19 @@ SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (sleep) + +AnnotationAssertion(Annotation( "ISBN:0192800981") "Any process in which an organism enters and maintains a periodic, readily reversible state of reduced awareness and metabolic activity. Usually accompanied by physical relaxation, the onset of sleep in humans and other mammals is marked by a change in the electrical activity of the brain.") +AnnotationAssertion( "Wikipedia:Sleep") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "diapause") +AnnotationAssertion( "dormancy") +AnnotationAssertion( "lethargus") +AnnotationAssertion( "GO:0030431") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "sleep") +SubClassOf( ) + # Class: (peristalsis) AnnotationAssertion(Annotation( "ISBN:0198506732") "A wavelike sequence of involuntary muscular contraction and relaxation that passes along a tubelike structure, such as the intestine, impelling the contents onwards.") @@ -33664,7 +71234,6 @@ EquivalentClasses( ObjectIntersection AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways resulting in the breakdown of bile acids, any of a group of steroid carboxylic acids occurring in bile.") AnnotationAssertion( "GO:0019613") -AnnotationAssertion( "MetaCyc:7ALPHADEHYDROX-PWY") AnnotationAssertion( "bile acid breakdown") AnnotationAssertion( "bile acid catabolism") AnnotationAssertion( "bile acid degradation") @@ -33702,7 +71271,6 @@ AnnotationAssertion( "A strict definition of neurotransmitter receptor activity would limit its use to receptor activity at the postsynaptic membrane as part of synaptic transmission, but we recognize that usage is often much broader than this. For the strict use case, please see 'postsynaptic neurotransmitter receptor activity'") AnnotationAssertion(rdfs:label "neurotransmitter receptor activity") SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectAllValuesFrom( )) @@ -33768,8 +71336,29 @@ AnnotationAssertion(Annotation( "cellular_component") AnnotationAssertion( "GO:0030659") AnnotationAssertion(rdfs:label "cytoplasmic vesicle membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (Golgi-associated vesicle membrane) + +AnnotationAssertion(Annotation( "GOC:mah") "The lipid bilayer surrounding a vesicle associated with the Golgi apparatus.") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "Golgi vesicle membrane") +AnnotationAssertion( "GO:0030660") +AnnotationAssertion(rdfs:label "Golgi-associated vesicle membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (chitosome membrane) + +AnnotationAssertion(Annotation( "GOC:mah") "The lipid bilayer surrounding a chitosome.") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0030661") +AnnotationAssertion(rdfs:label "chitosome membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (secretory granule membrane) AnnotationAssertion(Annotation( "GOC:mah") "The lipid bilayer surrounding a secretory granule.") @@ -33777,18 +71366,287 @@ AnnotationAssertion( "cellular_component") AnnotationAssertion( "GO:0030667") AnnotationAssertion(rdfs:label "secretory granule membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (eggshell formation) + +AnnotationAssertion(Annotation( "GOC:mtg_sensu") Annotation( "ISBN:0879694238") Annotation( "PMID:10822261") "Construction of the eggshell, a product of the somatic follicle cell epithelium and a structure that supports the egg in a hostile environment, minimizing water loss whilst allowing gas exchanges essential for embryonic respiration.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0030703") +AnnotationAssertion(rdfs:label "eggshell formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectAllValuesFrom( )) + +# Class: (vitelline membrane formation) + +AnnotationAssertion(Annotation( "ISBN:0879694238") "Construction of the vitelline membrane portion of the egg shell, a rigid structure required to maintain the shape of the egg.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0030704") +AnnotationAssertion(rdfs:label "vitelline membrane formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (cytoskeleton-dependent intracellular transport) + +AnnotationAssertion(Annotation( "GOC:mah") "The directed movement of substances along cytoskeletal fibers such as microfilaments or microtubules within a cell.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0030705") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "cytoskeleton-dependent intracellular transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (follicle cell of egg chamber development) + +AnnotationAssertion(Annotation( "GOC:mtg_sensu") Annotation( "PMID:10822261") "The process that occurs during oogenesis involving the ovarian follicle cells, somatic cells which surround the germ cells of an ovary. An example of this is found in Drosophila melanogaster.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0030707") +AnnotationAssertion(rdfs:label "follicle cell of egg chamber development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectAllValuesFrom( )) + +# Class: (germ-line stem cell population maintenance) + +AnnotationAssertion(Annotation( "ISBN:0879694238") "Any process by which an organism or tissue maintains a population of germ-line stem cells.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0030718") +AnnotationAssertion(rdfs:label "germ-line stem cell population maintenance") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (oocyte localization involved in germarium-derived egg chamber formation) + +AnnotationAssertion(Annotation( "GOC:mtg_sensu") Annotation( "PMID:10449356") "Directed movement of the oocyte, following its specification, from its original central position in the cyst to a posterior position relative to the nurse cells of the egg chamber, and its maintenance in this posterior location. This is the first sign of anterior-posterior asymmetry in the developing egg chamber.") +AnnotationAssertion( "establishment and maintenance of oocyte localization in egg chamber") +AnnotationAssertion( "establishment and maintenance of oocyte position during oogenesis") +AnnotationAssertion(Annotation( "GOC:mah") "oocyte localisation involved in germarium-derived egg chamber formation") +AnnotationAssertion( "oogenesis, establishment and maintenance of oocyte localization") +AnnotationAssertion( "oogenesis, oocyte localization") +AnnotationAssertion( "oocyte positioning during oogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "oocyte localization during germarium-derived egg chamber formation") +AnnotationAssertion( "oocyte localization during oogenesis") +AnnotationAssertion( "GO:0030720") +AnnotationAssertion(rdfs:label "oocyte localization involved in germarium-derived egg chamber formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectAllValuesFrom( )) + +# Class: (regulation of nucleotide biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nucleotides.") +AnnotationAssertion( "regulation of nucleotide anabolism") +AnnotationAssertion( "regulation of nucleotide biosynthesis") +AnnotationAssertion( "regulation of nucleotide formation") +AnnotationAssertion( "regulation of nucleotide synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0030808") +AnnotationAssertion(rdfs:label "regulation of nucleotide biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of nucleotide biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nucleotides.") +AnnotationAssertion( "down regulation of nucleotide biosynthetic process") +AnnotationAssertion( "down-regulation of nucleotide biosynthetic process") +AnnotationAssertion( "downregulation of nucleotide biosynthetic process") +AnnotationAssertion( "negative regulation of nucleotide anabolism") +AnnotationAssertion( "negative regulation of nucleotide biosynthesis") +AnnotationAssertion( "negative regulation of nucleotide formation") +AnnotationAssertion( "negative regulation of nucleotide synthesis") +AnnotationAssertion( "inhibition of nucleotide biosynthetic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0030809") +AnnotationAssertion(rdfs:label "negative regulation of nucleotide biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of nucleotide biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nucleotides.") +AnnotationAssertion( "positive regulation of nucleotide anabolism") +AnnotationAssertion( "positive regulation of nucleotide biosynthesis") +AnnotationAssertion( "positive regulation of nucleotide formation") +AnnotationAssertion( "positive regulation of nucleotide synthesis") +AnnotationAssertion( "up regulation of nucleotide biosynthetic process") +AnnotationAssertion( "up-regulation of nucleotide biosynthetic process") +AnnotationAssertion( "upregulation of nucleotide biosynthetic process") +AnnotationAssertion( "activation of nucleotide biosynthetic process") +AnnotationAssertion( "stimulation of nucleotide biosynthetic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0030810") +AnnotationAssertion(rdfs:label "positive regulation of nucleotide biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of nucleotide catabolic process) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of nucleotides.") +AnnotationAssertion( "regulation of nucleotide breakdown") +AnnotationAssertion( "regulation of nucleotide catabolism") +AnnotationAssertion( "regulation of nucleotide degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0030811") +AnnotationAssertion(rdfs:label "regulation of nucleotide catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of nucleotide catabolic process) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of nucleotides.") +AnnotationAssertion( "down regulation of nucleotide catabolic process") +AnnotationAssertion( "down-regulation of nucleotide catabolic process") +AnnotationAssertion( "downregulation of nucleotide catabolic process") +AnnotationAssertion( "negative regulation of nucleotide breakdown") +AnnotationAssertion( "negative regulation of nucleotide catabolism") +AnnotationAssertion( "negative regulation of nucleotide degradation") +AnnotationAssertion( "inhibition of nucleotide catabolic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0030812") +AnnotationAssertion(rdfs:label "negative regulation of nucleotide catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of nucleotide catabolic process) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of nucleotides.") +AnnotationAssertion( "positive regulation of nucleotide breakdown") +AnnotationAssertion( "positive regulation of nucleotide catabolism") +AnnotationAssertion( "positive regulation of nucleotide degradation") +AnnotationAssertion( "up regulation of nucleotide catabolic process") +AnnotationAssertion( "up-regulation of nucleotide catabolic process") +AnnotationAssertion( "upregulation of nucleotide catabolic process") +AnnotationAssertion( "activation of nucleotide catabolic process") +AnnotationAssertion( "stimulation of nucleotide catabolic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0030813") +AnnotationAssertion(rdfs:label "positive regulation of nucleotide catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (prostate gland development) + +AnnotationAssertion(Annotation( "PMID:11839751") "The process whose specific outcome is the progression of the prostate gland over time, from its formation to the mature structure. The prostate gland is a partly muscular, partly glandular body that is situated near the base of the mammalian male urethra and secretes an alkaline viscid fluid which is a major constituent of the ejaculatory fluid.") +AnnotationAssertion( "prostate development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0030850") +AnnotationAssertion(rdfs:label "prostate gland development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (granulocyte differentiation) + +AnnotationAssertion(Annotation( "GOC:ecd") Annotation( "http://life.nthu.edu.tw/~g864204/dict-search1.htm") "The process in which a myeloid precursor cell acquires the specialized features of a granulocyte. Granulocytes are a class of leukocytes characterized by the presence of granules in their cytoplasm. These cells are active in allergic immune reactions such as arthritic inflammation and rashes. This class includes basophils, eosinophils and neutrophils.") +AnnotationAssertion( "granulocyte cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0030851") +AnnotationAssertion(rdfs:label "granulocyte differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of granulocyte differentiation) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of granulocyte differentiation.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0030852") +AnnotationAssertion(rdfs:label "regulation of granulocyte differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of granulocyte differentiation) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of granulocyte differentiation.") +AnnotationAssertion( "down regulation of granulocyte differentiation") +AnnotationAssertion( "down-regulation of granulocyte differentiation") +AnnotationAssertion( "downregulation of granulocyte differentiation") +AnnotationAssertion( "inhibition of granulocyte differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0030853") +AnnotationAssertion(rdfs:label "negative regulation of granulocyte differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of granulocyte differentiation) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of granulocyte differentiation.") +AnnotationAssertion( "up regulation of granulocyte differentiation") +AnnotationAssertion( "up-regulation of granulocyte differentiation") +AnnotationAssertion( "upregulation of granulocyte differentiation") +AnnotationAssertion( "activation of granulocyte differentiation") +AnnotationAssertion( "stimulation of granulocyte differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0030854") +AnnotationAssertion(rdfs:label "positive regulation of granulocyte differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (epithelial cell differentiation) AnnotationAssertion(Annotation( "GOC:ecd") Annotation( "PMID:11839751") "The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell, any of the cells making up an epithelium.") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0030855") AnnotationAssertion(rdfs:label "epithelial cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (regulation of epithelial cell differentiation) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of epithelial cell differentiation.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0030856") +AnnotationAssertion(rdfs:label "regulation of epithelial cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of epithelial cell differentiation) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of epithelial cell differentiation.") +AnnotationAssertion( "down regulation of epithelial cell differentiation") +AnnotationAssertion( "down-regulation of epithelial cell differentiation") +AnnotationAssertion( "downregulation of epithelial cell differentiation") +AnnotationAssertion( "inhibition of epithelial cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0030857") +AnnotationAssertion(rdfs:label "negative regulation of epithelial cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of epithelial cell differentiation) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of epithelial cell differentiation.") +AnnotationAssertion( "up regulation of epithelial cell differentiation") +AnnotationAssertion( "up-regulation of epithelial cell differentiation") +AnnotationAssertion( "upregulation of epithelial cell differentiation") +AnnotationAssertion( "activation of epithelial cell differentiation") +AnnotationAssertion( "stimulation of epithelial cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0030858") +AnnotationAssertion(rdfs:label "positive regulation of epithelial cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (thyroid gland development) + +AnnotationAssertion(Annotation( "GOC:dgh") "The process whose specific outcome is the progression of the thyroid gland over time, from its formation to the mature structure. The thyroid gland is an endoderm-derived gland that produces thyroid hormone.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0030878") +AnnotationAssertion(rdfs:label "thyroid gland development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (mammary gland development) AnnotationAssertion(Annotation( "PMID:9576833") "The process whose specific outcome is the progression of the mammary gland over time, from its formation to the mature structure. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk. Its development starts with the formation of the mammary line and ends as the mature gland cycles between nursing and weaning stages.") @@ -33796,10 +71654,209 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:0030879") AnnotationAssertion(rdfs:label "mammary gland development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectAllValuesFrom( )) +# Class: (regulation of myeloid dendritic cell activation) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency or rate of myeloid dendritic cell activation.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0030885") +AnnotationAssertion(rdfs:label "regulation of myeloid dendritic cell activation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of myeloid dendritic cell activation) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of myeloid dendritic cell activation.") +AnnotationAssertion( "down regulation of myeloid dendritic cell activation") +AnnotationAssertion( "down-regulation of myeloid dendritic cell activation") +AnnotationAssertion( "downregulation of myeloid dendritic cell activation") +AnnotationAssertion( "inhibition of myeloid dendritic cell activation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0030886") +AnnotationAssertion(rdfs:label "negative regulation of myeloid dendritic cell activation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of myeloid dendritic cell activation) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that stimulates, induces or increases the rate of myeloid dendritic cell activation.") +AnnotationAssertion( "up regulation of myeloid dendritic cell activation") +AnnotationAssertion( "up-regulation of myeloid dendritic cell activation") +AnnotationAssertion( "upregulation of myeloid dendritic cell activation") +AnnotationAssertion( "activation of myeloid dendritic cell activation") +AnnotationAssertion( "stimulation of myeloid dendritic cell activation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0030887") +AnnotationAssertion(rdfs:label "positive regulation of myeloid dendritic cell activation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of B cell proliferation) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of B cell proliferation.") +AnnotationAssertion( "regulation of B lymphocyte proliferation") +AnnotationAssertion( "regulation of B-cell proliferation") +AnnotationAssertion( "regulation of B-lymphocyte proliferation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0030888") +AnnotationAssertion(rdfs:label "regulation of B cell proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of B cell proliferation) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents or reduces the rate or extent of B cell proliferation.") +AnnotationAssertion( "down regulation of B cell proliferation") +AnnotationAssertion( "down-regulation of B cell proliferation") +AnnotationAssertion( "downregulation of B cell proliferation") +AnnotationAssertion( "negative regulation of B lymphocyte proliferation") +AnnotationAssertion( "negative regulation of B-cell proliferation") +AnnotationAssertion( "negative regulation of B-lymphocyte proliferation") +AnnotationAssertion( "inhibition of B cell proliferation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0030889") +AnnotationAssertion(rdfs:label "negative regulation of B cell proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of B cell proliferation) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the rate or extent of B cell proliferation.") +AnnotationAssertion( "positive regulation of B lymphocyte proliferation") +AnnotationAssertion( "positive regulation of B-cell proliferation") +AnnotationAssertion( "positive regulation of B-lymphocyte proliferation") +AnnotationAssertion( "up regulation of B cell proliferation") +AnnotationAssertion( "up-regulation of B cell proliferation") +AnnotationAssertion( "upregulation of B cell proliferation") +AnnotationAssertion( "activation of B cell proliferation") +AnnotationAssertion( "stimulation of B cell proliferation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0030890") +AnnotationAssertion(rdfs:label "positive regulation of B cell proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (forebrain development) + +AnnotationAssertion(Annotation( "http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=forebrain") "The process whose specific outcome is the progression of the forebrain over time, from its formation to the mature structure. The forebrain is the anterior of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes especially the cerebral hemispheres, the thalamus, and the hypothalamus and especially in higher vertebrates is the main control center for sensory and associative information processing, visceral functions, and voluntary motor functions).") +AnnotationAssertion( "prosencephalon development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0030900") +AnnotationAssertion(rdfs:label "forebrain development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (midbrain development) + +AnnotationAssertion(Annotation( "http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=midbrain") "The process whose specific outcome is the progression of the midbrain over time, from its formation to the mature structure. The midbrain is the middle division of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes a ventral part containing the cerebral peduncles and a dorsal tectum containing the corpora quadrigemina and that surrounds the aqueduct of Sylvius connecting the third and fourth ventricles).") +AnnotationAssertion( "mesencephalon development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0030901") +AnnotationAssertion(rdfs:label "midbrain development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (hindbrain development) + +AnnotationAssertion(Annotation( "http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=hindbrain") "The process whose specific outcome is the progression of the hindbrain over time, from its formation to the mature structure. The hindbrain is the posterior of the three primary divisions of the developing chordate brain, or the corresponding part of the adult brain (in vertebrates, includes the cerebellum, pons, and medulla oblongata and controls the autonomic functions and equilibrium).") +AnnotationAssertion( "rhombencephalon development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0030902") +AnnotationAssertion(rdfs:label "hindbrain development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (notochord development) + +AnnotationAssertion(Annotation( "GOC:dgh") "The process whose specific outcome is the progression of the notochord over time, from its formation to the mature structure. The notochord is a mesoderm-derived structure located ventral of the developing nerve cord. In vertebrates, the notochord serves as a core around which other mesodermal cells form the vertebrae. In the most primitive chordates, which lack vertebrae, the notochord persists as a substitute for a vertebral column.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0030903") +AnnotationAssertion(rdfs:label "notochord development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (olfactory placode formation) + +AnnotationAssertion(Annotation( "GOC:dgh") "The formation of a thickening of the neural ectoderm in the head region of the vertebrate embryo which develops into the olfactory region of the nasal cavity.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0030910") +AnnotationAssertion(rdfs:label "olfactory placode formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (otic vesicle formation) + +AnnotationAssertion(Annotation( "GOC:dgh") "The process resulting in the transition of the otic placode into the otic vesicle, a transient embryonic structure formed during development of the vertebrate inner ear.") +AnnotationAssertion( "otocyst biosynthesis") +AnnotationAssertion( "otocyst formation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0030916") +AnnotationAssertion(rdfs:label "otic vesicle formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (midbrain-hindbrain boundary development) + +AnnotationAssertion(Annotation( "GOC:dgh") "The process whose specific outcome is the progression of the midbrain-hindbrain boundary over time, from its formation to the mature structure. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages.") +AnnotationAssertion( "MHB development") +AnnotationAssertion( "isthmic organizer development") +AnnotationAssertion( "isthmomesencephalic boundary development") +AnnotationAssertion( "isthmus development") +AnnotationAssertion( "midbrain-hindbrain orgainizer development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0030917") +AnnotationAssertion(rdfs:label "midbrain-hindbrain boundary development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (transmembrane collagen trimer) + +AnnotationAssertion(Annotation( "ISBN:0721639976") "Any collagen trimer that passes through a lipid bilayer membrane.") +AnnotationAssertion(Annotation( "ISBN:0198599587") "MACIT") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0030936") +AnnotationAssertion(rdfs:label "transmembrane collagen trimer") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (establishment or maintenance of microtubule cytoskeleton polarity) + +AnnotationAssertion(Annotation( "GOC:mah") "Any cellular process that results in the specification, formation or maintenance of polarized microtubule-based cytoskeletal structures.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0030951") +AnnotationAssertion(rdfs:label "establishment or maintenance of microtubule cytoskeleton polarity") +SubClassOf( ) +SubClassOf( ) + +# Class: (establishment or maintenance of cytoskeleton polarity) + +AnnotationAssertion(Annotation( "GOC:mah") "Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "cytoskeleton polarization") +AnnotationAssertion( "GO:0030952") +AnnotationAssertion(rdfs:label "establishment or maintenance of cytoskeleton polarity") +SubClassOf( ) +SubClassOf( ) + # Class: (intraciliary transport particle) AnnotationAssertion(Annotation( "GOC:cilia") Annotation( "GOC:kmv") Annotation( "PMID:14570576") Annotation( "PMID:22118932") Annotation( "PMID:23945166") "A nonmembrane-bound oligomeric protein complex that participates in bidirectional transport of molecules (cargo) along axonemal microtubules.") @@ -33834,6 +71891,66 @@ SubClassOf( ) DisjointClasses( ) +# Class: (pancreas development) + +AnnotationAssertion(Annotation( "GOC:cvs") "The process whose specific outcome is the progression of the pancreas over time, from its formation to the mature structure. The pancreas is an endoderm derived structure that produces precursors of digestive enzymes and blood glucose regulating hormones.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/23777"^^xsd:anyURI) +AnnotationAssertion( "Wikipedia:Pancreas") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0031016") +AnnotationAssertion(rdfs:label "pancreas development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (exocrine pancreas development) + +AnnotationAssertion(Annotation( "GOC:cvs") "The process whose specific outcome is the progression of the exocrine pancreas over time, from its formation to the mature structure. The exocrine pancreas produces and store zymogens of digestive enzymes, such as chymotrypsinogen and trypsinogen in the acinar cells.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0031017") +AnnotationAssertion(rdfs:label "exocrine pancreas development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (endocrine pancreas development) + +AnnotationAssertion(Annotation( "GOC:cvs") "The process whose specific outcome is the progression of the endocrine pancreas over time, from its formation to the mature structure. The endocrine pancreas is made up of islet cells that produce insulin, glucagon and somatostatin.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0031018") +AnnotationAssertion(rdfs:label "endocrine pancreas development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (nuclear migration along microfilament) + +AnnotationAssertion(Annotation( "GOC:mah") "The directed movement of the nucleus along microfilaments within the cell, mediated by motor proteins.") +AnnotationAssertion( "nuclear migration, microfilament-mediated") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0031022") +AnnotationAssertion(rdfs:label "nuclear migration along microfilament") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (actomyosin structure organization) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:jl") Annotation( "GOC:mah") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures containing both actin and myosin or paramyosin. The myosin may be organized into filaments.") +AnnotationAssertion( "actomyosin organization") +AnnotationAssertion( "actomyosin structure organisation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:mah") "actomyosin structure organization and biogenesis") +AnnotationAssertion( "GO:0031032") +AnnotationAssertion(rdfs:comment "Note that this term is a child of 'actin cytoskeleton organization and biogenesis ; GO:0030036' because the actin cytoskeleton is defined as actin filaments and associated proteins.") +AnnotationAssertion(rdfs:label "actomyosin structure organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + # Class: (dense core granule) AnnotationAssertion(Annotation( "NIF_Subcellular:sao772007592") Annotation( "PMID:14690495") "Electron-dense organelle with a granular internal matrix; contains proteins destined to be secreted.") @@ -33844,6 +71961,39 @@ AnnotationAssertion( "dense core granule") SubClassOf( ) +# Class: (hair follicle morphogenesis) + +AnnotationAssertion(Annotation( "GOC:ln") "The process in which the anatomical structures of the hair follicle are generated and organized.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0031069") +AnnotationAssertion(rdfs:label "hair follicle morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (embryonic camera-type eye development) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:mtg_sensu") "The process occurring during the embryonic phase whose specific outcome is the progression of the eye over time, from its formation to the mature structure.") +AnnotationAssertion( "embryonic eye development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0031076") +AnnotationAssertion(rdfs:label "embryonic camera-type eye development") +SubClassOf( ) +SubClassOf( ) + +# Class: (organelle membrane) + +AnnotationAssertion(Annotation( "GOC:dos") Annotation( "GOC:mah") "A membrane that is one of the two lipid bilayers of an organelle envelope or the outermost membrane of single membrane bound organelle.") +AnnotationAssertion( "NIF_Subcellular:sao830981606") +AnnotationAssertion( "cellular_component") +AnnotationAssertion(Annotation( "NIF_Subcellular:sao830981606") "intracellular membrane") +AnnotationAssertion( "GO:0031090") +AnnotationAssertion(rdfs:label "organelle membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (regeneration) AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:pr") "The regrowth of a lost or destroyed body part, such as an organ or tissue. This process may occur via renewal, repair, and/or growth alone (i.e. increase in size or mass).") @@ -33854,6 +72004,181 @@ AnnotationAssertion(rdfs:label "rege SubClassOf( ) SubClassOf( ) +# Class: (animal organ regeneration) + +AnnotationAssertion(Annotation( "GOC:mah") "The regrowth of a lost or destroyed animal organ.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0031100") +AnnotationAssertion(rdfs:label "animal organ regeneration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (fin regeneration) + +AnnotationAssertion(Annotation( "GOC:dgh") "The regrowth of fin tissue following its loss or destruction.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0031101") +AnnotationAssertion(rdfs:label "fin regeneration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (microtubule polymerization or depolymerization) + +AnnotationAssertion(Annotation( "GOC:mah") "Assembly or disassembly of microtubules by the addition or removal of tubulin heterodimers from a microtubule.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/23195"^^xsd:anyURI) +AnnotationAssertion( "microtubule dynamics") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0031109") +AnnotationAssertion(rdfs:label "microtubule polymerization or depolymerization") +SubClassOf( ) + +# Class: (regulation of microtubule polymerization or depolymerization) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of microtubule polymerization or depolymerization by the addition or removal of tubulin heterodimers from a microtubule.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0031110") +AnnotationAssertion(rdfs:label "regulation of microtubule polymerization or depolymerization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of microtubule polymerization or depolymerization) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule polymerization or depolymerization.") +AnnotationAssertion( "down regulation of microtubule polymerization or depolymerization") +AnnotationAssertion( "down-regulation of microtubule polymerization or depolymerization") +AnnotationAssertion( "downregulation of microtubule polymerization or depolymerization") +AnnotationAssertion( "inhibition of microtubule polymerization or depolymerization") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0031111") +AnnotationAssertion(rdfs:label "negative regulation of microtubule polymerization or depolymerization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of microtubule polymerization or depolymerization) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of microtubule polymerization or depolymerization.") +AnnotationAssertion( "up regulation of microtubule polymerization or depolymerization") +AnnotationAssertion( "up-regulation of microtubule polymerization or depolymerization") +AnnotationAssertion( "upregulation of microtubule polymerization or depolymerization") +AnnotationAssertion( "activation of microtubule polymerization or depolymerization") +AnnotationAssertion( "stimulation of microtubule polymerization or depolymerization") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0031112") +AnnotationAssertion(rdfs:label "positive regulation of microtubule polymerization or depolymerization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of microtubule polymerization) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of microtubule polymerization.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0031113") +AnnotationAssertion(rdfs:label "regulation of microtubule polymerization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of microtubule depolymerization) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of microtubule depolymerization.") +AnnotationAssertion( "regulation of microtubule disassembly") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0031114") +AnnotationAssertion(rdfs:label "regulation of microtubule depolymerization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of microtubule polymerization) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule polymerization.") +AnnotationAssertion( "down regulation of microtubule polymerization") +AnnotationAssertion( "down-regulation of microtubule polymerization") +AnnotationAssertion( "downregulation of microtubule polymerization") +AnnotationAssertion( "inhibition of microtubule polymerization") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0031115") +AnnotationAssertion(rdfs:label "negative regulation of microtubule polymerization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of microtubule polymerization) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of microtubule polymerization.") +AnnotationAssertion( "up regulation of microtubule polymerization") +AnnotationAssertion( "up-regulation of microtubule polymerization") +AnnotationAssertion( "upregulation of microtubule polymerization") +AnnotationAssertion( "activation of microtubule polymerization") +AnnotationAssertion( "stimulation of microtubule polymerization") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0031116") +AnnotationAssertion(rdfs:label "positive regulation of microtubule polymerization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of microtubule depolymerization) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of microtubule depolymerization.") +AnnotationAssertion( "microtubule destabilization") +AnnotationAssertion( "positive regulation of microtubule disassembly") +AnnotationAssertion( "up regulation of microtubule depolymerization") +AnnotationAssertion( "up-regulation of microtubule depolymerization") +AnnotationAssertion( "upregulation of microtubule depolymerization") +AnnotationAssertion( "activation of microtubule depolymerization") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "positive regulation of microtubule catastrophe") +AnnotationAssertion( "stimulation of microtubule depolymerization") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0031117") +AnnotationAssertion(rdfs:label "positive regulation of microtubule depolymerization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (cytoplasmic microtubule organization) + +AnnotationAssertion(Annotation( "GOC:mah") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures formed of microtubules and associated proteins in the cytoplasm of a cell.") +AnnotationAssertion( "cytoplasmic microtubule organisation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:mah") "cytoplasmic microtubule organization and biogenesis") +AnnotationAssertion( "GO:0031122") +AnnotationAssertion(rdfs:label "cytoplasmic microtubule organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (developmental induction) + +AnnotationAssertion(Annotation( "GOC:cjm") Annotation( "GOC:dph") Annotation( "GOC:mah") Annotation( "PMID:24503535") "A developmental process involving two tissues in which one tissue (the inducer) produces a signal that directs cell fate commitment of cells in the second tissue (the responder).") +AnnotationAssertion( ) +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0031128") +AnnotationAssertion(rdfs:label "developmental induction") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses( ObjectSomeValuesFrom( )) + +# Class: (pseudopodium) + +AnnotationAssertion(Annotation( "ISBN:0198506732") "A temporary protrusion or retractile process of a cell, associated with flowing movements of the protoplasm, and serving for locomotion and feeding.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/21139"^^xsd:anyURI) +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/21141"^^xsd:anyURI) +AnnotationAssertion( "Wikipedia:Pseudopod") +AnnotationAssertion( "pseudopod") +AnnotationAssertion( "pseudopodial protrusion") +AnnotationAssertion( "axopodium") +AnnotationAssertion( "lobopodium") +AnnotationAssertion( "reticulopodium") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0031143") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "pseudopodium") +SubClassOf( ) + +# Class: (neuron projection development) + +AnnotationAssertion(Annotation( "GOC:mah") "The process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).") +AnnotationAssertion( "neurite biosynthesis") +AnnotationAssertion(Annotation( "GOC:dph") "neurite development") +AnnotationAssertion( "neurite formation") +AnnotationAssertion( "neurite growth") +AnnotationAssertion( "neurite outgrowth") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0031175") +AnnotationAssertion(rdfs:label "neuron projection development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (biomineral tissue development) AnnotationAssertion(Annotation( "PMID:15132736") "Formation of hard tissues that consist mainly of inorganic compounds, and also contain a small amounts of organic matrices that are believed to play important roles in their formation.") @@ -33864,6 +72189,463 @@ AnnotationAssertion(rdfs:label "biom SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (cell leading edge) + +AnnotationAssertion(Annotation( "GOC:pg") "The area of a motile cell closest to the direction of movement.") +AnnotationAssertion( "front of cell") +AnnotationAssertion( "leading edge of cell") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0031252") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "cell leading edge") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cell projection membrane) + +AnnotationAssertion(Annotation( "GOC:krc") Annotation( "GOC:mah") "The portion of the plasma membrane surrounding a plasma membrane bounded cell surface projection.") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "membrane extension") +AnnotationAssertion( "membrane projection") +AnnotationAssertion( "GO:0031253") +AnnotationAssertion(rdfs:label "cell projection membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (leading edge membrane) + +AnnotationAssertion(Annotation( "GOC:mah") "The portion of the plasma membrane surrounding the leading edge of a motile cell.") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0031256") +AnnotationAssertion(rdfs:label "leading edge membrane") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (pseudopodium organization) + +AnnotationAssertion(Annotation( "GOC:pg") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a pseudopodium, a temporary protrusion or retractile process of a cell, associated with cellular movement.") +AnnotationAssertion( "pseudopodium organisation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:mah") "pseudopodium organization and biogenesis") +AnnotationAssertion( "GO:0031268") +AnnotationAssertion(rdfs:label "pseudopodium organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (pseudopodium assembly) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mah") Annotation( "GOC:pg") Annotation( "GOC:tb") "The assembly of a pseudopodium by rearrangement of the actin cytoskeleton and overlying membrane.") +AnnotationAssertion( "pseudopodium extension") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "pseudopodium formation") +AnnotationAssertion( "GO:0031269") +AnnotationAssertion(rdfs:label "pseudopodium assembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (pseudopodium retraction) + +AnnotationAssertion(Annotation( "GOC:pg") "The myosin-based contraction and retraction of a pseudopodium.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0031270") +AnnotationAssertion(rdfs:label "pseudopodium retraction") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of pseudopodium assembly) + +AnnotationAssertion(Annotation( "GOC:pg") "Any process that modulates the frequency, rate or extent of the assembly of pseudopodia.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "regulation of pseudopodium formation") +AnnotationAssertion( "GO:0031272") +AnnotationAssertion(rdfs:label "regulation of pseudopodium assembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of pseudopodium assembly) + +AnnotationAssertion(Annotation( "GOC:pg") "Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly of pseudopodia.") +AnnotationAssertion( "inhibition of pseudopodium formation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "down regulation of pseudopodium formation") +AnnotationAssertion( "down-regulation of pseudopodium formation") +AnnotationAssertion( "downregulation of pseudopodium formation") +AnnotationAssertion( "negative regulation of pseudopodium formation") +AnnotationAssertion( "GO:0031273") +AnnotationAssertion(rdfs:label "negative regulation of pseudopodium assembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of pseudopodium assembly) + +AnnotationAssertion(Annotation( "GOC:pg") "Any process that activates or increases the frequency, rate or extent of the assembly of pseudopodia.") +AnnotationAssertion( "activation of pseudopodium formation") +AnnotationAssertion( "stimulation of pseudopodium formation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") "positive regulation of pseudopodium formation") +AnnotationAssertion( "up regulation of pseudopodium formation") +AnnotationAssertion( "up-regulation of pseudopodium formation") +AnnotationAssertion( "upregulation of pseudopodium formation") +AnnotationAssertion( "GO:0031274") +AnnotationAssertion(rdfs:label "positive regulation of pseudopodium assembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of cellular metabolic process) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances.") +AnnotationAssertion( "regulation of cellular metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0031323") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "regulation of cellular metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of cellular metabolic process) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances.") +AnnotationAssertion( "down regulation of cellular metabolic process") +AnnotationAssertion( "down-regulation of cellular metabolic process") +AnnotationAssertion( "downregulation of cellular metabolic process") +AnnotationAssertion( "negative regulation of cellular metabolism") +AnnotationAssertion( "inhibition of cellular metabolic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0031324") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "negative regulation of cellular metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of cellular metabolic process) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances.") +AnnotationAssertion( "positive regulation of cellular metabolism") +AnnotationAssertion( "up regulation of cellular metabolic process") +AnnotationAssertion( "up-regulation of cellular metabolic process") +AnnotationAssertion( "upregulation of cellular metabolic process") +AnnotationAssertion( "activation of cellular metabolic process") +AnnotationAssertion( "stimulation of cellular metabolic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0031325") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "positive regulation of cellular metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of cellular biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.") +AnnotationAssertion( "regulation of cellular anabolism") +AnnotationAssertion( "regulation of cellular biosynthesis") +AnnotationAssertion( "regulation of cellular formation") +AnnotationAssertion( "regulation of cellular synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0031326") +AnnotationAssertion(rdfs:label "regulation of cellular biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of cellular biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.") +AnnotationAssertion( "down regulation of cellular biosynthetic process") +AnnotationAssertion( "down-regulation of cellular biosynthetic process") +AnnotationAssertion( "downregulation of cellular biosynthetic process") +AnnotationAssertion( "negative regulation of cellular anabolism") +AnnotationAssertion( "negative regulation of cellular biosynthesis") +AnnotationAssertion( "negative regulation of cellular formation") +AnnotationAssertion( "negative regulation of cellular synthesis") +AnnotationAssertion( "inhibition of cellular biosynthetic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0031327") +AnnotationAssertion(rdfs:label "negative regulation of cellular biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of cellular biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.") +AnnotationAssertion( "positive regulation of cellular anabolism") +AnnotationAssertion( "positive regulation of cellular biosynthesis") +AnnotationAssertion( "positive regulation of cellular formation") +AnnotationAssertion( "positive regulation of cellular synthesis") +AnnotationAssertion( "up regulation of cellular biosynthetic process") +AnnotationAssertion( "up-regulation of cellular biosynthetic process") +AnnotationAssertion( "upregulation of cellular biosynthetic process") +AnnotationAssertion( "activation of cellular biosynthetic process") +AnnotationAssertion( "stimulation of cellular biosynthetic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0031328") +AnnotationAssertion(rdfs:label "positive regulation of cellular biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of cellular catabolic process) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells.") +AnnotationAssertion( "regulation of cellular breakdown") +AnnotationAssertion( "regulation of cellular catabolism") +AnnotationAssertion( "regulation of cellular degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0031329") +AnnotationAssertion(rdfs:label "regulation of cellular catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of cellular catabolic process) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells.") +AnnotationAssertion( "down regulation of cellular catabolic process") +AnnotationAssertion( "down-regulation of cellular catabolic process") +AnnotationAssertion( "downregulation of cellular catabolic process") +AnnotationAssertion( "negative regulation of cellular breakdown") +AnnotationAssertion( "negative regulation of cellular catabolism") +AnnotationAssertion( "negative regulation of cellular degradation") +AnnotationAssertion( "inhibition of cellular catabolic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0031330") +AnnotationAssertion(rdfs:label "negative regulation of cellular catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of cellular catabolic process) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells.") +AnnotationAssertion( "positive regulation of cellular breakdown") +AnnotationAssertion( "positive regulation of cellular catabolism") +AnnotationAssertion( "positive regulation of cellular degradation") +AnnotationAssertion( "up regulation of cellular catabolic process") +AnnotationAssertion( "up-regulation of cellular catabolic process") +AnnotationAssertion( "upregulation of cellular catabolic process") +AnnotationAssertion( "activation of cellular catabolic process") +AnnotationAssertion( "stimulation of cellular catabolic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0031331") +AnnotationAssertion(rdfs:label "positive regulation of cellular catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of protein-containing complex assembly) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of protein complex assembly.") +AnnotationAssertion( "down regulation of protein complex assembly") +AnnotationAssertion( "down-regulation of protein complex assembly") +AnnotationAssertion( "downregulation of protein complex assembly") +AnnotationAssertion( "inhibition of protein complex assembly") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "negative regulation of protein complex assembly") +AnnotationAssertion( "GO:0031333") +AnnotationAssertion(rdfs:label "negative regulation of protein-containing complex assembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of protein-containing complex assembly) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of protein complex assembly.") +AnnotationAssertion( "up regulation of protein complex assembly") +AnnotationAssertion( "up-regulation of protein complex assembly") +AnnotationAssertion( "upregulation of protein complex assembly") +AnnotationAssertion( "activation of protein complex assembly") +AnnotationAssertion( "stimulation of protein complex assembly") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "positive regulation of protein complex assembly") +AnnotationAssertion( "GO:0031334") +AnnotationAssertion(rdfs:label "positive regulation of protein-containing complex assembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (regulation of vesicle fusion) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of vesicle fusion.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0031338") +AnnotationAssertion(rdfs:label "regulation of vesicle fusion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of vesicle fusion) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of vesicle fusion.") +AnnotationAssertion( "down regulation of vesicle fusion") +AnnotationAssertion( "down-regulation of vesicle fusion") +AnnotationAssertion( "downregulation of vesicle fusion") +AnnotationAssertion( "inhibition of vesicle fusion") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0031339") +AnnotationAssertion(rdfs:label "negative regulation of vesicle fusion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of vesicle fusion) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of vesicle fusion.") +AnnotationAssertion( "up regulation of vesicle fusion") +AnnotationAssertion( "up-regulation of vesicle fusion") +AnnotationAssertion( "upregulation of vesicle fusion") +AnnotationAssertion( "activation of vesicle fusion") +AnnotationAssertion( "stimulation of vesicle fusion") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0031340") +AnnotationAssertion(rdfs:label "positive regulation of vesicle fusion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of cell projection organization) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell projections.") +AnnotationAssertion( "regulation of cell projection organisation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:mah") "regulation of cell projection organization and biogenesis") +AnnotationAssertion( "GO:0031344") +AnnotationAssertion(rdfs:label "regulation of cell projection organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of cell projection organization) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell projections.") +AnnotationAssertion(Annotation( "GOC:mah") "down regulation of cell projection organization") +AnnotationAssertion( "down-regulation of cell projection organization") +AnnotationAssertion( "downregulation of cell projection organization") +AnnotationAssertion( "negative regulation of cell projection organisation") +AnnotationAssertion( "inhibition of cell projection organization") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:mah") "negative regulation of cell projection organization and biogenesis") +AnnotationAssertion( "GO:0031345") +AnnotationAssertion(rdfs:label "negative regulation of cell projection organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of cell projection organization) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of the process involved in the formation, arrangement of constituent parts, or disassembly of cell projections.") +AnnotationAssertion( "positive regulation of cell projection organisation") +AnnotationAssertion( "up regulation of cell projection organization") +AnnotationAssertion( "up-regulation of cell projection organization") +AnnotationAssertion( "upregulation of cell projection organization") +AnnotationAssertion( "activation of cell projection organization") +AnnotationAssertion( "stimulation of cell projection organization") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:mah") "positive regulation of cell projection organization and biogenesis") +AnnotationAssertion( "GO:0031346") +AnnotationAssertion(rdfs:label "positive regulation of cell projection organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of defense response) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of a defense response.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0031347") +AnnotationAssertion(rdfs:label "regulation of defense response") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (negative regulation of defense response) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of a defense response.") +AnnotationAssertion( "down regulation of defense response") +AnnotationAssertion( "down-regulation of defense response") +AnnotationAssertion( "downregulation of defense response") +AnnotationAssertion( "inhibition of defense response") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0031348") +AnnotationAssertion(rdfs:label "negative regulation of defense response") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of defense response) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of a defense response.") +AnnotationAssertion( "up regulation of defense response") +AnnotationAssertion( "up-regulation of defense response") +AnnotationAssertion( "upregulation of defense response") +AnnotationAssertion( "activation of defense response") +AnnotationAssertion( "stimulation of defense response") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0031349") +AnnotationAssertion(rdfs:label "positive regulation of defense response") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of protein modification process) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:tb") "Any process that modulates the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0031399") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "regulation of protein modification process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of protein modification process) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:tb") "Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein.") +AnnotationAssertion( "down regulation of protein modification") +AnnotationAssertion( "down-regulation of protein modification") +AnnotationAssertion( "downregulation of protein modification") +AnnotationAssertion( "inhibition of protein modification") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0031400") +AnnotationAssertion(rdfs:label "negative regulation of protein modification process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of protein modification process) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:tb") "Any process that activates or increases the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein.") +AnnotationAssertion( "up regulation of protein modification") +AnnotationAssertion( "up-regulation of protein modification") +AnnotationAssertion( "upregulation of protein modification") +AnnotationAssertion( "activation of protein modification") +AnnotationAssertion( "stimulation of protein modification") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0031401") +AnnotationAssertion(rdfs:label "positive regulation of protein modification process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (sodium ion binding) + +AnnotationAssertion(Annotation( "GOC:mah") "Binding to a sodium ion (Na+).") +AnnotationAssertion( "Na+ ion binding") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0031402") +AnnotationAssertion(rdfs:label "sodium ion binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (carboxylic acid binding) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "ISBN:0198506732") "Binding to a carboxylic acid, an organic acid containing one or more carboxyl (COOH) groups or anions (COO-).") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0031406") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "carboxylic acid binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (pigment binding) + +AnnotationAssertion(Annotation( "GOC:mah") "Binding to a pigment, a general or particular coloring matter in living organisms, e.g. melanin.") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0031409") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "pigment binding") +SubClassOf( ) + # Class: (cytoplasmic vesicle) AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:mah") Annotation( "GOC:vesicles") "A vesicle found in the cytoplasm of a cell.") @@ -33881,6 +72663,7 @@ AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "cytoplasmic vesicle") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) @@ -33891,6 +72674,15 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0031413") AnnotationAssertion(rdfs:label "regulation of buoyancy") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (alkali metal ion binding) + +AnnotationAssertion(Annotation( "GOC:mah") "Binding to an alkali metal ion; alkali metals are those elements in group Ia of the periodic table, with the exception of hydrogen.") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0031420") +AnnotationAssertion(rdfs:label "alkali metal ion binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (keratinization) @@ -33902,6 +72694,360 @@ SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (protein-containing complex localization) + +AnnotationAssertion(Annotation( "GOC:mah") "A localization process that acts on a protein complex; the complex is transported to, or maintained in, a specific location.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/22021"^^xsd:anyURI) +AnnotationAssertion( "GO:0034629") +AnnotationAssertion( "establishment and maintenance of protein complex localization") +AnnotationAssertion(Annotation( "GOC:mah") "protein complex localisation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:mah") "cellular protein complex localisation") +AnnotationAssertion( "cellular protein complex localization") +AnnotationAssertion( "cellular protein-containing complex localization") +AnnotationAssertion( "establishment and maintenance of cellular protein complex localization") +AnnotationAssertion( "protein complex localization") +AnnotationAssertion( "GO:0031503") +AnnotationAssertion(rdfs:label "protein-containing complex localization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (motile cilium) + +AnnotationAssertion(Annotation( "GOC:cilia") Annotation( "GOC:dgh") Annotation( "GOC:kmv") Annotation( "PMID:17009929") Annotation( "PMID:20144998") Annotation( "PMID:22118931") "A cilium which may have a variable arrangement of axonemal microtubules and also contains molecular motors. It may beat with a whip-like pattern that promotes cell motility or transport of fluids and other cells across a cell surface, such as on epithelial cells that line the lumenal ducts of various tissues; or they may display a distinct twirling motion that directs fluid flow asymmetrically across the cellular surface to affect asymmetric body plan organization. Motile cilia can be found in single as well as multiple copies per cell.") +AnnotationAssertion( "GO:0009434") +AnnotationAssertion( "GO:0031512") +AnnotationAssertion( "motile cilia") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "microtubule-based flagellum") +AnnotationAssertion( "motile primary cilia") +AnnotationAssertion( "motile primary cilium") +AnnotationAssertion( "motile secondary cilium") +AnnotationAssertion( "nodal cilium") +AnnotationAssertion( "GO:0031514") +AnnotationAssertion(rdfs:label "motile cilium") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (neuromuscular junction) + +AnnotationAssertion(Annotation( "GOC:nln") "The junction between the axon of a motor neuron and a muscle fiber. In response to the arrival of action potentials, the presynaptic button releases molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane of the muscle fiber, leading to a change in post-synaptic potential.") +AnnotationAssertion( "NIF_Subcellular:sao1124888485") +AnnotationAssertion( "Wikipedia:Neuromuscular_junction") +AnnotationAssertion( "cellular_component") +AnnotationAssertion(Annotation( "GOC:ha") "NMJ") +AnnotationAssertion(Annotation( "NIF_Subcellular:nlx_subcell_20090512") "motor endplate") +AnnotationAssertion( "GO:0031594") +AnnotationAssertion(rdfs:comment "In vertebrates, the term 'neuromuscular junction' is limited to synapses targeting skeletal muscle fibers - all of which are cholinergic and excitatory. Both inhibitory and excitatory neuromuscular junctions exist in invertebrates, utilizing a range of neurotransmitters including glutamate, GABA and 5-HT.") +AnnotationAssertion(rdfs:label "neuromuscular junction") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of myelination) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the formation of a myelin sheath around nerve axons.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0031641") +AnnotationAssertion(rdfs:label "regulation of myelination") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (negative regulation of myelination) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of the formation of a myelin sheath around nerve axons.") +AnnotationAssertion( "down regulation of myelination") +AnnotationAssertion( "down-regulation of myelination") +AnnotationAssertion( "downregulation of myelination") +AnnotationAssertion( "inhibition of myelination") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0031642") +AnnotationAssertion(rdfs:label "negative regulation of myelination") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (positive regulation of myelination) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of the formation of a myelin sheath around nerve axons.") +AnnotationAssertion( "up regulation of myelination") +AnnotationAssertion( "up-regulation of myelination") +AnnotationAssertion( "upregulation of myelination") +AnnotationAssertion( "activation of myelination") +AnnotationAssertion( "stimulation of myelination") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0031643") +AnnotationAssertion(rdfs:label "positive regulation of myelination") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of nervous system process) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mah") Annotation( "GOC:tb") "Any process that modulates the frequency, rate or extent of a neurophysiological process, an organ system process carried out by any of the organs or tissues of the nervous system.") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "regulation of neurological process") +AnnotationAssertion( "regulation of neurological system process") +AnnotationAssertion( "regulation of neurophysiological process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0031644") +AnnotationAssertion(rdfs:label "regulation of nervous system process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (negative regulation of nervous system process) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mah") Annotation( "GOC:tb") "Any process that stops, prevents, or reduces the frequency, rate or extent of a neurophysiological process.") +AnnotationAssertion( "down regulation of neurological process") +AnnotationAssertion( "down-regulation of neurological process") +AnnotationAssertion( "downregulation of neurological process") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "negative regulation of neurological process") +AnnotationAssertion( "negative regulation of neurological system process") +AnnotationAssertion( "negative regulation of neurophysiological process") +AnnotationAssertion( "inhibition of neurological process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0031645") +AnnotationAssertion(rdfs:label "negative regulation of nervous system process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (positive regulation of nervous system process) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mah") Annotation( "GOC:tb") "Any process that activates or increases the frequency, rate or extent of a neurophysiological process.") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "positive regulation of neurological process") +AnnotationAssertion( "positive regulation of neurological system process") +AnnotationAssertion( "positive regulation of neurophysiological process") +AnnotationAssertion( "up regulation of neurological process") +AnnotationAssertion( "up-regulation of neurological process") +AnnotationAssertion( "upregulation of neurological process") +AnnotationAssertion( "activation of neurological process") +AnnotationAssertion( "stimulation of neurological process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0031646") +AnnotationAssertion(rdfs:label "positive regulation of nervous system process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (CCR2 chemokine receptor binding) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:nln") "Binding to a CCR2 chemokine receptor.") +AnnotationAssertion( "monocyte chemoattractant protein 1 receptor binding") +AnnotationAssertion( "CCR2 chemokine receptor ligand") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0031727") +AnnotationAssertion(rdfs:label "CCR2 chemokine receptor binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (CX3C chemokine receptor binding) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:nln") "Binding to a CX3C chemokine receptor.") +AnnotationAssertion( "fractalkine receptor binding") +AnnotationAssertion( "CX3C chemokine receptor ligand") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0031737") +AnnotationAssertion(rdfs:label "CX3C chemokine receptor binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of glucocorticoid metabolic process) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving glucocorticoids.") +AnnotationAssertion( "regulation of glucocorticoid metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0031943") +AnnotationAssertion(rdfs:label "regulation of glucocorticoid metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of glucocorticoid metabolic process) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving glucocorticoids.") +AnnotationAssertion( "down regulation of glucocorticoid metabolic process") +AnnotationAssertion( "down-regulation of glucocorticoid metabolic process") +AnnotationAssertion( "downregulation of glucocorticoid metabolic process") +AnnotationAssertion( "negative regulation of glucocorticoid metabolism") +AnnotationAssertion( "inhibition of glucocorticoid metabolic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0031944") +AnnotationAssertion(rdfs:label "negative regulation of glucocorticoid metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of glucocorticoid metabolic process) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving glucocorticoids.") +AnnotationAssertion( "positive regulation of glucocorticoid metabolism") +AnnotationAssertion( "up regulation of glucocorticoid metabolic process") +AnnotationAssertion( "up-regulation of glucocorticoid metabolic process") +AnnotationAssertion( "upregulation of glucocorticoid metabolic process") +AnnotationAssertion( "activation of glucocorticoid metabolic process") +AnnotationAssertion( "stimulation of glucocorticoid metabolic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0031945") +AnnotationAssertion(rdfs:label "positive regulation of glucocorticoid metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of glucocorticoid biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucocorticoids.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0031946") +AnnotationAssertion(rdfs:label "regulation of glucocorticoid biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of glucocorticoid biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucocorticoids.") +AnnotationAssertion( "down regulation of glucocorticoid biosynthetic process") +AnnotationAssertion( "down-regulation of glucocorticoid biosynthetic process") +AnnotationAssertion( "downregulation of glucocorticoid biosynthetic process") +AnnotationAssertion( "inhibition of glucocorticoid biosynthetic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0031947") +AnnotationAssertion(rdfs:label "negative regulation of glucocorticoid biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of glucocorticoid biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucocorticoids.") +AnnotationAssertion( "up regulation of glucocorticoid biosynthetic process") +AnnotationAssertion( "up-regulation of glucocorticoid biosynthetic process") +AnnotationAssertion( "upregulation of glucocorticoid biosynthetic process") +AnnotationAssertion( "activation of glucocorticoid biosynthetic process") +AnnotationAssertion( "stimulation of glucocorticoid biosynthetic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0031948") +AnnotationAssertion(rdfs:label "positive regulation of glucocorticoid biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of glucocorticoid catabolic process) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glucocorticoids.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0031949") +AnnotationAssertion(rdfs:label "regulation of glucocorticoid catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (negative regulation of glucocorticoid catabolic process) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glucocorticoids.") +AnnotationAssertion( "down regulation of glucocorticoid catabolic process") +AnnotationAssertion( "down-regulation of glucocorticoid catabolic process") +AnnotationAssertion( "downregulation of glucocorticoid catabolic process") +AnnotationAssertion( "inhibition of glucocorticoid catabolic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0031950") +AnnotationAssertion(rdfs:label "negative regulation of glucocorticoid catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (positive regulation of glucocorticoid catabolic process) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glucocorticoids.") +AnnotationAssertion( "up regulation of glucocorticoid catabolic process") +AnnotationAssertion( "up-regulation of glucocorticoid catabolic process") +AnnotationAssertion( "upregulation of glucocorticoid catabolic process") +AnnotationAssertion( "activation of glucocorticoid catabolic process") +AnnotationAssertion( "stimulation of glucocorticoid catabolic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0031951") +AnnotationAssertion(rdfs:label "positive regulation of glucocorticoid catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (corticosteroid receptor signaling pathway) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "PMID:11027914") Annotation( "PMID:12606724") "The series of molecular signals initiated by corticosteroid binding to its receptor, and ending with the regulation of a downstream cellular process, e.g. transcription.") +AnnotationAssertion( "corticosteroid receptor signalling pathway") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0031958") +AnnotationAssertion(rdfs:label "corticosteroid receptor signaling pathway") +SubClassOf( ) +SubClassOf( ) + +# Class: (response to corticosteroid) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "PMID:11027914") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticosteroid hormone stimulus. A corticosteroid is a steroid hormone that is produced in the adrenal cortex. Corticosteroids are involved in a wide range of physiologic systems such as stress response, immune response and regulation of inflammation, carbohydrate metabolism, protein catabolism, blood electrolyte levels, and behavior. They include glucocorticoids and mineralocorticoids.") +AnnotationAssertion(Annotation( "GOC:dos") "response to corticosteroid stimulus") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0031960") +AnnotationAssertion(rdfs:label "response to corticosteroid") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (nuclear membrane) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:pz") "Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space.") +AnnotationAssertion( "NIF_Subcellular:sao1687101204") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0031965") +AnnotationAssertion(rdfs:label "nuclear membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (organelle envelope) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:pz") "A double membrane structure enclosing an organelle, including two lipid bilayers and the region between them. In some cases, an organelle envelope may have more than two membranes.") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0031967") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "organelle envelope") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (organelle outer membrane) + +AnnotationAssertion(Annotation( "GOC:mah") "The outer, i.e. cytoplasm-facing in a cellular organelle, lipid bilayer of an organelle envelope.") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0031968") +AnnotationAssertion(rdfs:label "organelle outer membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (membrane-enclosed lumen) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:mah") "The enclosed volume within a sealed membrane or between two sealed membranes. Encompasses the volume enclosed by the membranes of a particular organelle, e.g. endoplasmic reticulum lumen, or the space between the two lipid bilayers of a double membrane surrounding an organelle, e.g. nuclear envelope lumen.") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0031974") +AnnotationAssertion(rdfs:label "membrane-enclosed lumen") +SubClassOf( ) +DisjointClasses( ) + +# Class: (envelope) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:pz") "A multilayered structure surrounding all or part of a cell; encompasses one or more lipid bilayers, and may include a cell wall layer; also includes the space between layers.") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0031975") +AnnotationAssertion(rdfs:label "envelope") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (nuclear lumen) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:pz") "The volume enclosed by the nuclear inner membrane.") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0031981") +AnnotationAssertion(rdfs:label "nuclear lumen") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (vesicle) AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:pz") Annotation( "GOC:vesicles") "Any small, fluid-filled, spherical organelle enclosed by membrane.") @@ -33916,6 +73062,765 @@ AnnotationAssertion( "vesicle") SubClassOf( ) +# Class: (locomotion involved in locomotory behavior) + +AnnotationAssertion(Annotation( "GOC:mah") "Self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement.") +AnnotationAssertion( "locomotion during locomotory behaviour") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0031987") +AnnotationAssertion(rdfs:label "locomotion involved in locomotory behavior") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (positive regulation of insulin secretion) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of the regulated release of insulin.") +AnnotationAssertion( "up regulation of insulin secretion") +AnnotationAssertion( "up-regulation of insulin secretion") +AnnotationAssertion( "upregulation of insulin secretion") +AnnotationAssertion( "activation of insulin secretion") +AnnotationAssertion( "stimulation of insulin secretion") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032024") +AnnotationAssertion(rdfs:label "positive regulation of insulin secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (bile acid binding) + +AnnotationAssertion(Annotation( "GOC:rph") "Binding to a bile acid, a steroid carboxylic acids occurring in bile.") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0032052") +AnnotationAssertion(rdfs:label "bile acid binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of translational initiation in response to stress) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents or reduces the rate of translation initiation as a result of a stimulus indicating the organism is under stress.") +AnnotationAssertion( "down regulation of translation initiation in response to stress") +AnnotationAssertion( "down-regulation of translation initiation in response to stress") +AnnotationAssertion( "downregulation of translation initiation in response to stress") +AnnotationAssertion( "inhibition of translation initiation in response to stress") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032057") +AnnotationAssertion(rdfs:label "negative regulation of translational initiation in response to stress") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of translational initiation in response to stress) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of translation initiation as a result of a stimulus indicating the organism is under stress.") +AnnotationAssertion( "up regulation of translation initiation in response to stress") +AnnotationAssertion( "up-regulation of translation initiation in response to stress") +AnnotationAssertion( "upregulation of translation initiation in response to stress") +AnnotationAssertion( "activation of translation initiation in response to stress") +AnnotationAssertion( "stimulation of translation initiation in response to stress") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032058") +AnnotationAssertion(rdfs:label "positive regulation of translational initiation in response to stress") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (bleb) + +AnnotationAssertion(Annotation( "GOC:mtg_apoptosis") Annotation( "PMID:12083798") Annotation( "PMID:16624291") Annotation( "Wikipedia:Bleb_(cell_biology)") "A cell extension caused by localized decoupling of the cytoskeleton from the plasma membrane and characterized by rapid formation, rounded shape, and scarcity of organelles within the protrusion. Blebs are formed during apoptosis and other cellular processes, including cell locomotion, cell division, and as a result of physical or chemical stresses.") +AnnotationAssertion( "Wikipedia:Bleb_(cell_biology)") +AnnotationAssertion(Annotation( "GOC:pr") "plasma membrane bleb") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0032059") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "bleb") +SubClassOf( ) + +# Class: (bleb assembly) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:mtg_apoptosis") Annotation( "PMID:12083798") Annotation( "PMID:16624291") Annotation( "Wikipedia:Bleb_(cell_biology)") "The assembly of a bleb, a cell extension caused by localized decoupling of the cytoskeleton from the plasma membrane and characterized by rapid formation, rounded shape, and scarcity of organelles within the protrusion. Plasma membrane blebbing occurs during apoptosis and other cellular processes, including cell locomotion, cell division, and as a result of physical or chemical stresses.") +AnnotationAssertion(Annotation( "GOC:pr") "blebbing") +AnnotationAssertion(Annotation( "GOC:pr") "membrane blebbing") +AnnotationAssertion( "cell blebbing") +AnnotationAssertion(Annotation( "GOC:pr") "plasma membrane bleb assembly") +AnnotationAssertion(Annotation( "GOC:pr") "plasma membrane blebbing") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032060") +AnnotationAssertion(rdfs:label "bleb assembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (maintenance of protein location in cell cortex) + +AnnotationAssertion(Annotation( "GOC:vw") "A process in which a protein or protein complex is maintained in a specific location in the cell cortex.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "cortical protein anchoring") +AnnotationAssertion( "GO:0032065") +AnnotationAssertion(rdfs:label "maintenance of protein location in cell cortex") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of nuclease activity) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of nuclease activity, the hydrolysis of ester linkages within nucleic acids.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "nuclease regulator activity") +AnnotationAssertion( "GO:0032069") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "regulation of nuclease activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (regulation of deoxyribonuclease activity) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of deoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "DNase regulator") +AnnotationAssertion( "deoxyribonuclease regulator") +AnnotationAssertion( "GO:0032070") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "regulation of deoxyribonuclease activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (negative regulation of nuclease activity) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops or reduces the rate of nuclease activity, the hydrolysis of ester linkages within nucleic acids.") +AnnotationAssertion( "down regulation of nuclease activity") +AnnotationAssertion( "down-regulation of nuclease activity") +AnnotationAssertion( "downregulation of nuclease activity") +AnnotationAssertion( "inhibition of nuclease activity") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "nuclease inhibitor") +AnnotationAssertion( "GO:0032074") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "negative regulation of nuclease activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (positive regulation of nuclease activity) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of nuclease activity, the hydrolysis of ester linkages within nucleic acids.") +AnnotationAssertion( "up regulation of nuclease activity") +AnnotationAssertion( "up-regulation of nuclease activity") +AnnotationAssertion( "upregulation of nuclease activity") +AnnotationAssertion( "activation of nuclease activity") +AnnotationAssertion( "stimulation of nuclease activity") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "nuclease activator") +AnnotationAssertion( "GO:0032075") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "positive regulation of nuclease activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (negative regulation of deoxyribonuclease activity) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops or reduces the rate of deoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid.") +AnnotationAssertion( "down regulation of deoxyribonuclease activity") +AnnotationAssertion( "down-regulation of deoxyribonuclease activity") +AnnotationAssertion( "downregulation of deoxyribonuclease activity") +AnnotationAssertion( "inhibition of deoxyribonuclease activity") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "DNase inhibitor") +AnnotationAssertion( "deoxyribonuclease inhibitor") +AnnotationAssertion( "GO:0032076") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "negative regulation of deoxyribonuclease activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (positive regulation of deoxyribonuclease activity) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of deoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid.") +AnnotationAssertion( "up regulation of deoxyribonuclease activity") +AnnotationAssertion( "up-regulation of deoxyribonuclease activity") +AnnotationAssertion( "upregulation of deoxyribonuclease activity") +AnnotationAssertion( "activation of deoxyribonuclease activity") +AnnotationAssertion( "stimulation of deoxyribonuclease activity") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "DNase activator") +AnnotationAssertion( "deoxyribonuclease activator") +AnnotationAssertion( "GO:0032077") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "positive regulation of deoxyribonuclease activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (negative regulation of protein binding) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of protein binding.") +AnnotationAssertion( "down regulation of protein binding") +AnnotationAssertion( "down-regulation of protein binding") +AnnotationAssertion( "downregulation of protein binding") +AnnotationAssertion( "inhibition of protein binding") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032091") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "negative regulation of protein binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of protein binding) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of protein binding.") +AnnotationAssertion( "up regulation of protein binding") +AnnotationAssertion( "up-regulation of protein binding") +AnnotationAssertion( "upregulation of protein binding") +AnnotationAssertion( "activation of protein binding") +AnnotationAssertion( "stimulation of protein binding") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032092") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "positive regulation of protein binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of response to external stimulus) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of a response to an external stimulus.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032101") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.") +AnnotationAssertion(rdfs:label "regulation of response to external stimulus") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (negative regulation of response to external stimulus) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of a response to an external stimulus.") +AnnotationAssertion( "down regulation of response to external stimulus") +AnnotationAssertion( "down-regulation of response to external stimulus") +AnnotationAssertion( "downregulation of response to external stimulus") +AnnotationAssertion( "inhibition of response to external stimulus") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032102") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.") +AnnotationAssertion(rdfs:label "negative regulation of response to external stimulus") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of response to external stimulus) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates, maintains or increases the rate of a response to an external stimulus.") +AnnotationAssertion( "up regulation of response to external stimulus") +AnnotationAssertion( "up-regulation of response to external stimulus") +AnnotationAssertion( "upregulation of response to external stimulus") +AnnotationAssertion( "activation of response to external stimulus") +AnnotationAssertion( "stimulation of response to external stimulus") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032103") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.") +AnnotationAssertion(rdfs:label "positive regulation of response to external stimulus") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (dense core granule membrane) + +AnnotationAssertion(Annotation( "GOC:mah") "The lipid bilayer surrounding a dense core granule.") +AnnotationAssertion(Annotation( "GOC:kmv") "dense core vesicle membrane") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0032127") +AnnotationAssertion(rdfs:label "dense core granule membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (regulation of synaptic transmission, cholinergic) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032222") +AnnotationAssertion(rdfs:label "regulation of synaptic transmission, cholinergic") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of synaptic transmission, cholinergic) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine.") +AnnotationAssertion( "down regulation of synaptic transmission, cholinergic") +AnnotationAssertion( "down-regulation of synaptic transmission, cholinergic") +AnnotationAssertion( "downregulation of synaptic transmission, cholinergic") +AnnotationAssertion( "inhibition of synaptic transmission, cholinergic") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032223") +AnnotationAssertion(rdfs:label "negative regulation of synaptic transmission, cholinergic") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of synaptic transmission, cholinergic) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates, maintains or increases the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine.") +AnnotationAssertion( "up regulation of synaptic transmission, cholinergic") +AnnotationAssertion( "up-regulation of synaptic transmission, cholinergic") +AnnotationAssertion( "upregulation of synaptic transmission, cholinergic") +AnnotationAssertion( "activation of synaptic transmission, cholinergic") +AnnotationAssertion( "stimulation of synaptic transmission, cholinergic") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032224") +AnnotationAssertion(rdfs:label "positive regulation of synaptic transmission, cholinergic") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of synaptic transmission, dopaminergic) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of dopaminergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter dopamine.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032225") +AnnotationAssertion(rdfs:label "regulation of synaptic transmission, dopaminergic") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of synaptic transmission, dopaminergic) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates, maintains or increases the frequency, rate or extent of dopaminergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter dopamine.") +AnnotationAssertion( "up regulation of synaptic transmission, dopaminergic") +AnnotationAssertion( "up-regulation of synaptic transmission, dopaminergic") +AnnotationAssertion( "upregulation of synaptic transmission, dopaminergic") +AnnotationAssertion( "activation of synaptic transmission, dopaminergic") +AnnotationAssertion( "stimulation of synaptic transmission, dopaminergic") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032226") +AnnotationAssertion(rdfs:label "positive regulation of synaptic transmission, dopaminergic") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of synaptic transmission, dopaminergic) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of dopaminergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter dopamine.") +AnnotationAssertion( "down regulation of synaptic transmission, dopaminergic") +AnnotationAssertion( "down-regulation of synaptic transmission, dopaminergic") +AnnotationAssertion( "downregulation of synaptic transmission, dopaminergic") +AnnotationAssertion( "inhibition of synaptic transmission, dopaminergic") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032227") +AnnotationAssertion(rdfs:label "negative regulation of synaptic transmission, dopaminergic") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of synaptic transmission, GABAergic) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA).") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032228") +AnnotationAssertion(rdfs:label "regulation of synaptic transmission, GABAergic") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of synaptic transmission, GABAergic) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA).") +AnnotationAssertion( "down regulation of synaptic transmission, GABAergic") +AnnotationAssertion( "down-regulation of synaptic transmission, GABAergic") +AnnotationAssertion( "downregulation of synaptic transmission, GABAergic") +AnnotationAssertion( "inhibition of synaptic transmission, GABAergic") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032229") +AnnotationAssertion(rdfs:label "negative regulation of synaptic transmission, GABAergic") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of synaptic transmission, GABAergic) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates, maintains or increases the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA).") +AnnotationAssertion( "up regulation of synaptic transmission, GABAergic") +AnnotationAssertion( "up-regulation of synaptic transmission, GABAergic") +AnnotationAssertion( "upregulation of synaptic transmission, GABAergic") +AnnotationAssertion( "activation of synaptic transmission, GABAergic") +AnnotationAssertion( "stimulation of synaptic transmission, GABAergic") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032230") +AnnotationAssertion(rdfs:label "positive regulation of synaptic transmission, GABAergic") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of actin filament bundle assembly) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the assembly of actin filament bundles.") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "regulation of actin cable assembly") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") "regulation of actin filament bundle formation") +AnnotationAssertion( "GO:0032231") +AnnotationAssertion(rdfs:label "regulation of actin filament bundle assembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (negative regulation of actin filament bundle assembly) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly of actin filament bundles.") +AnnotationAssertion( "down regulation of actin filament bundle formation") +AnnotationAssertion( "down-regulation of actin filament bundle formation") +AnnotationAssertion( "downregulation of actin filament bundle formation") +AnnotationAssertion( "inhibition of actin filament bundle formation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032232") +AnnotationAssertion(rdfs:label "negative regulation of actin filament bundle assembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (positive regulation of actin filament bundle assembly) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of the assembly of actin filament bundles.") +AnnotationAssertion( "up regulation of actin filament bundle formation") +AnnotationAssertion( "up-regulation of actin filament bundle formation") +AnnotationAssertion( "upregulation of actin filament bundle formation") +AnnotationAssertion( "activation of actin filament bundle formation") +AnnotationAssertion( "stimulation of actin filament bundle formation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032233") +AnnotationAssertion(rdfs:label "positive regulation of actin filament bundle assembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (adenosine transport) + +AnnotationAssertion(Annotation( "GOC:mah") "The directed movement of adenosine, adenine riboside, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032238") +AnnotationAssertion(rdfs:label "adenosine transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of nucleobase-containing compound transport) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport") +AnnotationAssertion( "GO:0032239") +AnnotationAssertion(rdfs:label "regulation of nucleobase-containing compound transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of nucleobase-containing compound transport) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion( "down regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport") +AnnotationAssertion( "down-regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport") +AnnotationAssertion( "downregulation of nucleobase, nucleoside, nucleotide and nucleic acid transport") +AnnotationAssertion( "inhibition of nucleobase, nucleoside, nucleotide and nucleic acid transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport") +AnnotationAssertion( "GO:0032240") +AnnotationAssertion(rdfs:label "negative regulation of nucleobase-containing compound transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of nucleobase-containing compound transport) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion( "up regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport") +AnnotationAssertion( "up-regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport") +AnnotationAssertion( "upregulation of nucleobase, nucleoside, nucleotide and nucleic acid transport") +AnnotationAssertion( "activation of nucleobase, nucleoside, nucleotide and nucleic acid transport") +AnnotationAssertion( "stimulation of nucleobase, nucleoside, nucleotide and nucleic acid transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid transport") +AnnotationAssertion( "GO:0032241") +AnnotationAssertion(rdfs:label "positive regulation of nucleobase-containing compound transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of nucleoside transport) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the directed movement of a nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032242") +AnnotationAssertion(rdfs:label "regulation of nucleoside transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of nucleoside transport) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion( "down regulation of nucleoside transport") +AnnotationAssertion( "down-regulation of nucleoside transport") +AnnotationAssertion( "downregulation of nucleoside transport") +AnnotationAssertion( "inhibition of nucleoside transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032243") +AnnotationAssertion(rdfs:label "negative regulation of nucleoside transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of nucleoside transport) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of the directed movement of a nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion( "up regulation of nucleoside transport") +AnnotationAssertion( "up-regulation of nucleoside transport") +AnnotationAssertion( "upregulation of nucleoside transport") +AnnotationAssertion( "activation of nucleoside transport") +AnnotationAssertion( "stimulation of nucleoside transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032244") +AnnotationAssertion(rdfs:label "positive regulation of nucleoside transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of purine nucleoside transport) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the directed movement of a purine nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032245") +AnnotationAssertion(rdfs:label "regulation of purine nucleoside transport") +SubClassOf( ) + +# Class: (negative regulation of purine nucleoside transport) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a purine nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion( "down regulation of purine nucleoside transport") +AnnotationAssertion( "down-regulation of purine nucleoside transport") +AnnotationAssertion( "downregulation of purine nucleoside transport") +AnnotationAssertion( "inhibition of purine nucleoside transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032247") +AnnotationAssertion(rdfs:label "negative regulation of purine nucleoside transport") +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of purine nucleoside transport) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of the directed movement of a purine nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion( "up regulation of purine nucleoside transport") +AnnotationAssertion( "up-regulation of purine nucleoside transport") +AnnotationAssertion( "upregulation of purine nucleoside transport") +AnnotationAssertion( "activation of purine nucleoside transport") +AnnotationAssertion( "stimulation of purine nucleoside transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032248") +AnnotationAssertion(rdfs:label "positive regulation of purine nucleoside transport") +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of adenosine transport) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the directed movement of adenosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032249") +AnnotationAssertion(rdfs:label "regulation of adenosine transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (negative regulation of adenosine transport) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of adenosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion( "down regulation of adenosine transport") +AnnotationAssertion( "down-regulation of adenosine transport") +AnnotationAssertion( "downregulation of adenosine transport") +AnnotationAssertion( "inhibition of adenosine transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032250") +AnnotationAssertion(rdfs:label "negative regulation of adenosine transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (positive regulation of adenosine transport) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of the directed movement of adenosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion( "up regulation of adenosine transport") +AnnotationAssertion( "up-regulation of adenosine transport") +AnnotationAssertion( "upregulation of adenosine transport") +AnnotationAssertion( "activation of adenosine transport") +AnnotationAssertion( "stimulation of adenosine transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032251") +AnnotationAssertion(rdfs:label "positive regulation of adenosine transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (secretory granule localization) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process in which a secretory granule is transported to, and/or maintained in, a specific location within the cell.") +AnnotationAssertion(Annotation( "GOC:mah") "secretory granule localisation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "secretory granule clustering") +AnnotationAssertion( "GO:0032252") +AnnotationAssertion(rdfs:label "secretory granule localization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (dense core granule localization) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process in which a dense core granule is transported to, and/or maintained in, a specific location within the cell.") +AnnotationAssertion(Annotation( "GOC:mah") "dense core granule localisation") +AnnotationAssertion(Annotation( "GOC:kmv") "dense core vesicle localization") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "dense core granule clustering") +AnnotationAssertion( "GO:0032253") +AnnotationAssertion(rdfs:label "dense core granule localization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of protein polymerization) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the process of creating protein polymers.") +AnnotationAssertion( "regulation of protein polymerisation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032271") +AnnotationAssertion(rdfs:label "regulation of protein polymerization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of protein polymerization) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of the process of creating protein polymers.") +AnnotationAssertion( "down regulation of protein polymerization") +AnnotationAssertion( "down-regulation of protein polymerization") +AnnotationAssertion( "downregulation of protein polymerization") +AnnotationAssertion( "inhibition of protein polymerization") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032272") +AnnotationAssertion(rdfs:label "negative regulation of protein polymerization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of protein polymerization) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of the process of creating protein polymers.") +AnnotationAssertion( "up regulation of protein polymerization") +AnnotationAssertion( "up-regulation of protein polymerization") +AnnotationAssertion( "upregulation of protein polymerization") +AnnotationAssertion( "activation of protein polymerization") +AnnotationAssertion( "stimulation of protein polymerization") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032273") +AnnotationAssertion(rdfs:label "positive regulation of protein polymerization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (gonadotropin secretion) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "ISBN:0721662544") "The regulated release of a gonadotropin, any hormone that stimulates the gonads, especially follicle-stimulating hormone and luteinizing hormone.") +AnnotationAssertion( "gonadotrophin secretion") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032274") +AnnotationAssertion(rdfs:label "gonadotropin secretion") +SubClassOf( ) + +# Class: (luteinizing hormone secretion) + +AnnotationAssertion(Annotation( "ISBN:0198506732") "The regulated release of luteinizing hormone, a gonadotropic glycoprotein hormone secreted by the anterior pituitary.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032275") +AnnotationAssertion(rdfs:label "luteinizing hormone secretion") +SubClassOf( ) + +# Class: (regulation of gonadotropin secretion) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the regulated release of a gonadotropin.") +AnnotationAssertion( "regulation of gonadotrophin secretion") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032276") +AnnotationAssertion(rdfs:label "regulation of gonadotropin secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (negative regulation of gonadotropin secretion) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a gonadotropin.") +AnnotationAssertion( "down regulation of gonadotropin secretion") +AnnotationAssertion( "down-regulation of gonadotropin secretion") +AnnotationAssertion( "downregulation of gonadotropin secretion") +AnnotationAssertion(Annotation( "GOC:dph") "negative regulation of gonadotrophin secretion") +AnnotationAssertion( "inhibition of gonadotropin secretion") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032277") +AnnotationAssertion(rdfs:label "negative regulation of gonadotropin secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (positive regulation of gonadotropin secretion) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of the regulated release of a gonadotropin.") +AnnotationAssertion(Annotation( "GOC:dph") "positive regulation of gonadotrophin secretion") +AnnotationAssertion( "up regulation of gonadotropin secretion") +AnnotationAssertion( "up-regulation of gonadotropin secretion") +AnnotationAssertion( "upregulation of gonadotropin secretion") +AnnotationAssertion( "activation of gonadotropin secretion") +AnnotationAssertion( "stimulation of gonadotropin secretion") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032278") +AnnotationAssertion(rdfs:label "positive regulation of gonadotropin secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (myelin assembly) + +AnnotationAssertion(Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:tb") "The process in which the wraps of cell membrane that constitute myelin are laid down around an axon in the central or peripheral nervous system.") +AnnotationAssertion( "myelin sheath assembly") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "myelin formation") +AnnotationAssertion( "GO:0032288") +AnnotationAssertion(rdfs:label "myelin assembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (central nervous system myelin formation) + +AnnotationAssertion(Annotation( "GOC:dgh") "The process in which the wraps of cell membrane that constitute myelin are laid down around an axon by an oligodendrocyte in the central nervous system.") +AnnotationAssertion( "central nervous system myelin sheath formation") +AnnotationAssertion( "myelin formation in central nervous system") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032289") +AnnotationAssertion(rdfs:label "central nervous system myelin formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectAllValuesFrom( )) + +# Class: (peripheral nervous system myelin formation) + +AnnotationAssertion(Annotation( "GOC:dgh") "The process in which the wraps of cell membrane that constitute myelin are laid down around an axon by Schwann cells in the peripheral nervous system.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/19106"^^xsd:anyURI) +AnnotationAssertion( "myelin formation in peripheral nervous system") +AnnotationAssertion( "peripheral nervous system myelin sheath formation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032290") +AnnotationAssertion(rdfs:label "peripheral nervous system myelin formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (axon ensheathment in central nervous system) + +AnnotationAssertion(Annotation( "GOC:dgh") "The process in which a glial cell membrane closes around an axon in the central nervous system. This can be a myelinating or a non-myelinating neuron-glial interaction.") +AnnotationAssertion( "ensheathment of axons in central nervous system") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032291") +AnnotationAssertion(rdfs:label "axon ensheathment in central nervous system") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectAllValuesFrom( )) + +# Class: (peripheral nervous system axon ensheathment) + +AnnotationAssertion(Annotation( "GOC:dgh") "The process in which a Schwann cell membrane closes around an axon in the peripheral nervous system. This can be a myelinating or a non-myelinating neuron-glial interaction.") +AnnotationAssertion( "ensheathment of axons in peripheral nervous system") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032292") +AnnotationAssertion(rdfs:label "peripheral nervous system axon ensheathment") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of chondrocyte differentiation) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of chondrocyte differentiation.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032330") +AnnotationAssertion(rdfs:label "regulation of chondrocyte differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of chondrocyte differentiation) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of chondrocyte differentiation.") +AnnotationAssertion( "down regulation of chondrocyte differentiation") +AnnotationAssertion( "down-regulation of chondrocyte differentiation") +AnnotationAssertion( "downregulation of chondrocyte differentiation") +AnnotationAssertion( "inhibition of chondrocyte differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032331") +AnnotationAssertion(rdfs:label "negative regulation of chondrocyte differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of chondrocyte differentiation) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of chondrocyte differentiation.") +AnnotationAssertion( "up regulation of chondrocyte differentiation") +AnnotationAssertion( "up-regulation of chondrocyte differentiation") +AnnotationAssertion( "upregulation of chondrocyte differentiation") +AnnotationAssertion( "activation of chondrocyte differentiation") +AnnotationAssertion( "stimulation of chondrocyte differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032332") +AnnotationAssertion(rdfs:label "positive regulation of chondrocyte differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + # Class: (aldosterone metabolic process) AnnotationAssertion(Annotation( "PMID:16527843") "The chemical reactions and pathways involving aldosterone, a corticosteroid hormone that is produced by the zona glomerulosa of the adrenal cortex and regulates salt (sodium and potassium) and water balance.") @@ -33923,6 +73828,7 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0032341") AnnotationAssertion(rdfs:label "aldosterone metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ) @@ -33935,6 +73841,7 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:0032342") AnnotationAssertion(rdfs:label "aldosterone biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ) @@ -33942,6 +73849,403 @@ SubClassOf( ) SubClassOf( ) +# Class: (aldosterone catabolic process) + +AnnotationAssertion(Annotation( "PMID:16527843") "The chemical reactions and pathways resulting in the breakdown of aldosterone, a corticosteroid hormone that is produced by the zona glomerulosa of the adrenal cortex and regulates salt (sodium and potassium) and water balance.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032343") +AnnotationAssertion(rdfs:label "aldosterone catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of aldosterone metabolic process) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving aldosterone.") +AnnotationAssertion( "regulation of aldosterone metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032344") +AnnotationAssertion(rdfs:label "regulation of aldosterone metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of aldosterone metabolic process) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving aldosterone.") +AnnotationAssertion( "down regulation of aldosterone metabolic process") +AnnotationAssertion( "down-regulation of aldosterone metabolic process") +AnnotationAssertion( "downregulation of aldosterone metabolic process") +AnnotationAssertion( "negative regulation of aldosterone metabolism") +AnnotationAssertion( "inhibition of aldosterone metabolic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032345") +AnnotationAssertion(rdfs:label "negative regulation of aldosterone metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of aldosterone metabolic process) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving aldosterone.") +AnnotationAssertion( "positive regulation of aldosterone metabolism") +AnnotationAssertion( "up regulation of aldosterone metabolic process") +AnnotationAssertion( "up-regulation of aldosterone metabolic process") +AnnotationAssertion( "upregulation of aldosterone metabolic process") +AnnotationAssertion( "activation of aldosterone metabolic process") +AnnotationAssertion( "stimulation of aldosterone metabolic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032346") +AnnotationAssertion(rdfs:label "positive regulation of aldosterone metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of aldosterone biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of aldosterone.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032347") +AnnotationAssertion(rdfs:label "regulation of aldosterone biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of aldosterone biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of aldosterone.") +AnnotationAssertion( "down regulation of aldosterone biosynthetic process") +AnnotationAssertion( "down-regulation of aldosterone biosynthetic process") +AnnotationAssertion( "downregulation of aldosterone biosynthetic process") +AnnotationAssertion( "inhibition of aldosterone biosynthetic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032348") +AnnotationAssertion(rdfs:label "negative regulation of aldosterone biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of aldosterone biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of aldosterone.") +AnnotationAssertion( "up regulation of aldosterone biosynthetic process") +AnnotationAssertion( "up-regulation of aldosterone biosynthetic process") +AnnotationAssertion( "upregulation of aldosterone biosynthetic process") +AnnotationAssertion( "activation of aldosterone biosynthetic process") +AnnotationAssertion( "stimulation of aldosterone biosynthetic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032349") +AnnotationAssertion(rdfs:label "positive regulation of aldosterone biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of hormone metabolic process) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving any hormone.") +AnnotationAssertion( "regulation of hormone metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032350") +AnnotationAssertion(rdfs:label "regulation of hormone metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of hormone metabolic process) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving any hormone.") +AnnotationAssertion( "down regulation of hormone metabolic process") +AnnotationAssertion( "down-regulation of hormone metabolic process") +AnnotationAssertion( "downregulation of hormone metabolic process") +AnnotationAssertion( "negative regulation of hormone metabolism") +AnnotationAssertion( "inhibition of hormone metabolic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032351") +AnnotationAssertion(rdfs:label "negative regulation of hormone metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of hormone metabolic process) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving any hormone.") +AnnotationAssertion( "positive regulation of hormone metabolism") +AnnotationAssertion( "up regulation of hormone metabolic process") +AnnotationAssertion( "up-regulation of hormone metabolic process") +AnnotationAssertion( "upregulation of hormone metabolic process") +AnnotationAssertion( "activation of hormone metabolic process") +AnnotationAssertion( "stimulation of hormone metabolic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032352") +AnnotationAssertion(rdfs:label "positive regulation of hormone metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of hormone biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hormones.") +AnnotationAssertion( "down regulation of hormone biosynthetic process") +AnnotationAssertion( "down-regulation of hormone biosynthetic process") +AnnotationAssertion( "downregulation of hormone biosynthetic process") +AnnotationAssertion( "inhibition of hormone biosynthetic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032353") +AnnotationAssertion(rdfs:label "negative regulation of hormone biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (intracellular oxygen homeostasis) + +AnnotationAssertion(Annotation( "GOC:rph") "A homeostatic process involved in the maintenance of a steady state level of oxygen within a cell.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/24224"^^xsd:anyURI) +AnnotationAssertion( "oxygen homeostasis") +AnnotationAssertion( "cellular oxygen homeostasis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032364") +AnnotationAssertion(rdfs:label "intracellular oxygen homeostasis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (intracellular lipid transport) + +AnnotationAssertion(Annotation( "GOC:mah") "The directed movement of lipids within cells.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032365") +AnnotationAssertion(rdfs:label "intracellular lipid transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (regulation of lipid transport) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032368") +AnnotationAssertion(rdfs:label "regulation of lipid transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (negative regulation of lipid transport) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion( "down regulation of lipid transport") +AnnotationAssertion( "down-regulation of lipid transport") +AnnotationAssertion( "downregulation of lipid transport") +AnnotationAssertion( "inhibition of lipid transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032369") +AnnotationAssertion(rdfs:label "negative regulation of lipid transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (positive regulation of lipid transport) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion( "up regulation of lipid transport") +AnnotationAssertion( "up-regulation of lipid transport") +AnnotationAssertion( "upregulation of lipid transport") +AnnotationAssertion( "activation of lipid transport") +AnnotationAssertion( "stimulation of lipid transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032370") +AnnotationAssertion(rdfs:label "positive regulation of lipid transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (regulation of intracellular lipid transport) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the directed movement of lipids within cells.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032377") +AnnotationAssertion(rdfs:label "regulation of intracellular lipid transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of intracellular lipid transport) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of lipids within cells.") +AnnotationAssertion( "down regulation of intracellular lipid transport") +AnnotationAssertion( "down-regulation of intracellular lipid transport") +AnnotationAssertion( "downregulation of intracellular lipid transport") +AnnotationAssertion( "inhibition of intracellular lipid transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032378") +AnnotationAssertion(rdfs:label "negative regulation of intracellular lipid transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of intracellular lipid transport) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of the directed movement of lipids within cells.") +AnnotationAssertion( "up regulation of intracellular lipid transport") +AnnotationAssertion( "up-regulation of intracellular lipid transport") +AnnotationAssertion( "upregulation of intracellular lipid transport") +AnnotationAssertion( "activation of intracellular lipid transport") +AnnotationAssertion( "stimulation of intracellular lipid transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032379") +AnnotationAssertion(rdfs:label "positive regulation of intracellular lipid transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of intracellular transport) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the directed movement of substances within cells.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032386") +AnnotationAssertion(rdfs:label "regulation of intracellular transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of intracellular transport) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances within cells.") +AnnotationAssertion( "down regulation of intracellular transport") +AnnotationAssertion( "down-regulation of intracellular transport") +AnnotationAssertion( "downregulation of intracellular transport") +AnnotationAssertion( "inhibition of intracellular transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032387") +AnnotationAssertion(rdfs:label "negative regulation of intracellular transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of intracellular transport) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of the directed movement of substances within cells.") +AnnotationAssertion( "up regulation of intracellular transport") +AnnotationAssertion( "up-regulation of intracellular transport") +AnnotationAssertion( "upregulation of intracellular transport") +AnnotationAssertion( "activation of intracellular transport") +AnnotationAssertion( "stimulation of intracellular transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032388") +AnnotationAssertion(rdfs:label "positive regulation of intracellular transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (melanosome localization) + +AnnotationAssertion(Annotation( "GOC:ln") "Any process in which a melanosome is transported to, and/or maintained in, a specific location within the cell.") +AnnotationAssertion(Annotation( "GOC:mah") "melanosome localisation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032400") +AnnotationAssertion(rdfs:label "melanosome localization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (establishment of melanosome localization) + +AnnotationAssertion(Annotation( "GOC:mah") "The directed movement of a melanosome to a specific location.") +AnnotationAssertion(Annotation( "GOC:mah") "establishment of melanosome localisation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032401") +AnnotationAssertion(rdfs:label "establishment of melanosome localization") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (melanosome transport) + +AnnotationAssertion(Annotation( "GOC:ln") "The directed movement of melanosomes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032402") +AnnotationAssertion(rdfs:label "melanosome transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of transporter activity) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the activity of a transporter.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032409") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "regulation of transporter activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of transporter activity) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops or reduces the activity of a transporter.") +AnnotationAssertion( "down regulation of transporter activity") +AnnotationAssertion( "down-regulation of transporter activity") +AnnotationAssertion( "downregulation of transporter activity") +AnnotationAssertion( "inhibition of transporter activity") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032410") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "negative regulation of transporter activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (positive regulation of transporter activity) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the activity of a transporter.") +AnnotationAssertion( "up regulation of transporter activity") +AnnotationAssertion( "up-regulation of transporter activity") +AnnotationAssertion( "upregulation of transporter activity") +AnnotationAssertion( "activation of transporter activity") +AnnotationAssertion( "stimulation of transporter activity") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032411") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "positive regulation of transporter activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of monoatomic ion transmembrane transporter activity) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:tb") "Any process that modulates the activity of an ion transporter.") +AnnotationAssertion( "regulation of ion transmembrane transporter activity") +AnnotationAssertion(Annotation( "GOC:tb") "regulation of ion transporter activity") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032412") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "regulation of monoatomic ion transmembrane transporter activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of ion transmembrane transporter activity) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:tb") "Any process that stops or reduces the activity of an ion transporter.") +AnnotationAssertion( "down regulation of ion transporter activity") +AnnotationAssertion( "down-regulation of ion transporter activity") +AnnotationAssertion( "downregulation of ion transporter activity") +AnnotationAssertion(Annotation( "GOC:tb") "negative regulation of ion transporter activity") +AnnotationAssertion( "inhibition of ion transporter activity") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032413") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "negative regulation of ion transmembrane transporter activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (positive regulation of ion transmembrane transporter activity) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:tb") "Any process that activates or increases the activity of an ion transporter.") +AnnotationAssertion(Annotation( "GOC:tb") "positive regulation of ion transporter activity") +AnnotationAssertion( "up regulation of ion transporter activity") +AnnotationAssertion( "up-regulation of ion transporter activity") +AnnotationAssertion( "upregulation of ion transporter activity") +AnnotationAssertion( "activation of ion transporter activity") +AnnotationAssertion( "stimulation of ion transporter activity") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032414") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "positive regulation of ion transmembrane transporter activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (lysosome localization) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process in which a lysosome is transported to, and/or maintained in, a specific location.") +AnnotationAssertion(Annotation( "GOC:mah") "lysosome localisation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032418") +AnnotationAssertion(rdfs:label "lysosome localization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (actin filament bundle) AnnotationAssertion(Annotation( "GOC:mah") "An assembly of actin filaments that are on the same axis but may be oriented with the same or opposite polarities and may be packed with different levels of tightness.") @@ -33956,6 +74260,63 @@ SubClassOf( ObjectSomeValuesFrom( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (melanosome organization) + +AnnotationAssertion(Annotation( "GOC:vk") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a melanosome. A melanosome is a tissue-specific, membrane-bounded cytoplasmic organelle within which melanin pigments are synthesized and stored.") +AnnotationAssertion(Annotation( "GOC:mah") "melanosome organisation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:mah") "melanosome organization and biogenesis") +AnnotationAssertion( "GO:0032438") +AnnotationAssertion(rdfs:label "melanosome organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (Golgi calcium ion homeostasis) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process involved in the maintenance of an internal steady state of calcium ions within the Golgi apparatus of a cell or between the Golgi and its surroundings.") +AnnotationAssertion( "Golgi calcium ion concentration regulation") +AnnotationAssertion( "calcium ion homeostasis in Golgi") +AnnotationAssertion( "regulation of Golgi calcium ion concentration") +AnnotationAssertion( "regulation of calcium ion concentration in Golgi") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032468") +AnnotationAssertion(rdfs:label "Golgi calcium ion homeostasis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectAllValuesFrom( )) + +# Class: (Golgi calcium ion transport) + +AnnotationAssertion(Annotation( "GOC:mah") "The directed movement of calcium ions (Ca2+) into, out of or within the Golgi apparatus.") +AnnotationAssertion( "Golgi calcium transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032472") +AnnotationAssertion(rdfs:label "Golgi calcium ion transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (otolith morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dgh") "The process in which the anatomical structures of an otolith are generated and organized.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032474") +AnnotationAssertion(rdfs:label "otolith morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (otolith formation) + +AnnotationAssertion(Annotation( "GOC:dgh") "The process that gives rise to an otolith. This process pertains to the initial formation of a structure from unspecified parts.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032475") +AnnotationAssertion(rdfs:label "otolith formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (multicellular organismal process) AnnotationAssertion(Annotation( "GOC:curators") Annotation( "GOC:dph") Annotation( "GOC:isa_complete") Annotation( "GOC:tb") "Any biological process, occurring at the level of a multicellular organism, pertinent to its function.") @@ -34016,12 +74377,181 @@ AnnotationAssertion(rdfs:label "mult SubClassOf( ) SubClassOf( ) +# Class: (maintenance of protein location in cell) + +AnnotationAssertion(Annotation( "GOC:isa_complete") Annotation( "GOC:mah") "Any process in which a protein is maintained in a specific location within, or in the membrane of, a cell, and is prevented from moving elsewhere.") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "maintenance of protein localization in cell") +AnnotationAssertion( "GO:0032507") +AnnotationAssertion(rdfs:label "maintenance of protein location in cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectAllValuesFrom( )) + +# Class: (microvillus organization) + +AnnotationAssertion(Annotation( "GOC:mah") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a microvillus, a thin cylindrical membrane-covered projection on the surface of a cell.") +AnnotationAssertion( ) +AnnotationAssertion(Annotation( "GOC:mah") "microvillus organisation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:mah") "microvillus organization and biogenesis") +AnnotationAssertion( "GO:0032528") +AnnotationAssertion(rdfs:label "microvillus organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses( ObjectSomeValuesFrom( )) + +# Class: (follicle cell microvillus organization) + +AnnotationAssertion(Annotation( "GOC:sart") Annotation( "PMID:16507588") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a microvillus on a follicle cell. A microvillus is a thin cylindrical membrane-covered projection on the surface of an animal cell containing a core bundle of actin filaments.") +AnnotationAssertion(Annotation( "GOC:mah") "follicle cell microvillus organisation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:mah") "follicle cell microvillus organization and biogenesis") +AnnotationAssertion( "GO:0032529") +AnnotationAssertion(rdfs:label "follicle cell microvillus organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of microvillus organization) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a microvillus.") +AnnotationAssertion(Annotation( "GOC:mah") "regulation of microvillus organisation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:mah") "regulation of microvillus organization and biogenesis") +AnnotationAssertion( "GO:0032530") +AnnotationAssertion(rdfs:label "regulation of microvillus organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of follicle cell microvillus organization) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a microvillus on a follicle cell.") +AnnotationAssertion(Annotation( "GOC:mah") "regulation of follicle cell microvillus organisation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:mah") "regulation of follicle cell microvillus organization and biogenesis") +AnnotationAssertion( "GO:0032531") +AnnotationAssertion(rdfs:label "regulation of follicle cell microvillus organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of microvillus assembly) + +AnnotationAssertion(Annotation( "GOC:mah") "A process that modulates the formation of a microvillus.") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:mah") "regulation of microvillus biogenesis") +AnnotationAssertion( "GO:0032534") +AnnotationAssertion(rdfs:label "regulation of microvillus assembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (ribonucleoside binding) + +AnnotationAssertion(Annotation( "GOC:mah") "Binding to a ribonucleoside, a compound consisting of a purine or pyrimidine nitrogenous base linked to ribose.") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0032549") +AnnotationAssertion(rdfs:label "ribonucleoside binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (purine ribonucleoside binding) + +AnnotationAssertion(Annotation( "GOC:mah") "Binding to a purine ribonucleoside, a compound consisting of a purine base linked to ribose.") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0032550") +AnnotationAssertion(rdfs:label "purine ribonucleoside binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (ribonucleotide binding) + +AnnotationAssertion(Annotation( "GOC:mah") "Binding to a ribonucleotide, any compound consisting of a ribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety.") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0032553") +AnnotationAssertion(rdfs:label "ribonucleotide binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (purine ribonucleotide binding) + +AnnotationAssertion(Annotation( "GOC:mah") "Binding to a purine ribonucleotide, any compound consisting of a purine ribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety.") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0032555") +AnnotationAssertion(rdfs:label "purine ribonucleotide binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (adenyl ribonucleotide binding) + +AnnotationAssertion(Annotation( "GOC:mah") "Binding to an adenyl ribonucleotide, any compound consisting of adenosine esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety.") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0032559") +AnnotationAssertion(rdfs:label "adenyl ribonucleotide binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (response to progesterone) + +AnnotationAssertion(Annotation( "GOC:sl") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a progesterone stimulus.") +AnnotationAssertion(Annotation( "GOC:dos") "response to progesterone stimulus") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032570") +AnnotationAssertion(rdfs:label "response to progesterone") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (neuron projection membrane) + +AnnotationAssertion(Annotation( "GOC:mah") "The portion of the plasma membrane surrounding a neuron projection.") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0032589") +AnnotationAssertion(rdfs:label "neuron projection membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (dendrite membrane) + +AnnotationAssertion(Annotation( "GOC:mah") "The portion of the plasma membrane surrounding a dendrite.") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0032590") +AnnotationAssertion(rdfs:label "dendrite membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (protein transport within lipid bilayer) + +AnnotationAssertion(Annotation( "GOC:mah") "The directed movement of a protein from one location to another within a lipid bilayer.") +AnnotationAssertion( "protein translocation within membrane") +AnnotationAssertion( "receptor translocation within membrane") +AnnotationAssertion( "receptor transport within lipid bilayer") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032594") +AnnotationAssertion(rdfs:label "protein transport within lipid bilayer") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (RNA biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:txnOH") "The chemical reactions and pathways resulting in the formation of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. Includes polymerization of ribonucleotide monomers. Refers not only to transcription but also to e.g. viral RNA replication.") +AnnotationAssertion( "GO:0062103") +AnnotationAssertion( "RNA anabolism") +AnnotationAssertion( "RNA biosynthesis") +AnnotationAssertion( "RNA formation") +AnnotationAssertion( "RNA synthesis") +AnnotationAssertion( "double-stranded RNA biosynthesis") +AnnotationAssertion( "double-stranded RNA biosynthetic process") +AnnotationAssertion( "dsRNA biosynthesis") +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_telomere") Annotation( "GOC:nc") Annotation( "GOC:rl") "dsRNA biosynthetic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032774") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:comment "Note that, in some cases, viral RNA replication and viral transcription from RNA actually refer to the same process, but may be called differently depending on the focus of a specific research study.") +AnnotationAssertion(rdfs:label "RNA biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (bile acid secretion) AnnotationAssertion(Annotation( "GOC:ecd") "The regulated release of bile acid, composed of any of a group of steroid carboxylic acids occurring in bile, by a cell or a tissue.") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0032782") AnnotationAssertion(rdfs:label "bile acid secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) # Class: (monocarboxylic acid metabolic process) @@ -34033,8 +74563,152 @@ AnnotationAssertion( "GO:0032787") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "monocarboxylic acid metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (ribosome disassembly) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:vk") "The disaggregation of a ribosome into its constituent components; includes the dissociation of ribosomal subunits.") +AnnotationAssertion(Annotation( "GOC:db") Annotation( "PMID:9463391") "ribosome recycling") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "ribosome dissociation factor") +AnnotationAssertion( "GO:0032790") +AnnotationAssertion(rdfs:label "ribosome disassembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (lacrimal gland development) + +AnnotationAssertion(Annotation( "GOC:ln") "The process whose specific outcome is the progression of the lacrimal gland over time, from its formation to the mature structure. The lacrimal gland produces secretions that lubricate and protect the cornea of the eye.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032808") +AnnotationAssertion(rdfs:label "lacrimal gland development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (negative regulation of epinephrine secretion) + +AnnotationAssertion(Annotation( "GOC:vk") "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of epinephrine.") +AnnotationAssertion( "down regulation of epinephrine secretion") +AnnotationAssertion( "down-regulation of epinephrine secretion") +AnnotationAssertion( "downregulation of epinephrine secretion") +AnnotationAssertion( "negative regulation of adrenaline secretion") +AnnotationAssertion( "inhibition of epinephrine secretion") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032811") +AnnotationAssertion(rdfs:label "negative regulation of epinephrine secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of epinephrine secretion) + +AnnotationAssertion(Annotation( "GOC:vk") "Any process that activates or increases the frequency, rate or extent of the regulated release of epinephrine.") +AnnotationAssertion( "positive regulation of adrenaline secretion") +AnnotationAssertion( "up regulation of epinephrine secretion") +AnnotationAssertion( "up-regulation of epinephrine secretion") +AnnotationAssertion( "upregulation of epinephrine secretion") +AnnotationAssertion( "activation of epinephrine secretion") +AnnotationAssertion( "stimulation of epinephrine secretion") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032812") +AnnotationAssertion(rdfs:label "positive regulation of epinephrine secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (glomerulus development) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:mtg_kidney_jan10") "The progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the vertebrate kidney. The glomerulus is part of the nephron and is restricted to one body segment.") +AnnotationAssertion( "glomerular development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032835") +AnnotationAssertion(rdfs:label "glomerulus development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (glomerular basement membrane development) + +AnnotationAssertion(Annotation( "GOC:sr") "The process whose specific outcome is the progression of the glomerular basement membrane over time, from its formation to the mature structure. The glomerular basement membrane is the basal laminal portion of the glomerulus which performs the actual filtration.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032836") +AnnotationAssertion(rdfs:label "glomerular basement membrane development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (plasma membrane bounded cell projection cytoplasm) + +AnnotationAssertion(Annotation( "GOC:krc") Annotation( "GOC:mah") "All of the contents of a plasma membrane bounded cell projection, excluding the plasma membrane surrounding the projection.") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0032838") +AnnotationAssertion(rdfs:label "plasma membrane bounded cell projection cytoplasm") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (dendrite cytoplasm) + +AnnotationAssertion(Annotation( "GOC:mah") "All of the contents of a dendrite, excluding the surrounding plasma membrane.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/14472"^^xsd:anyURI) +AnnotationAssertion( "dendritic cytoplasm") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0032839") +AnnotationAssertion(rdfs:label "dendrite cytoplasm") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (calcitonin binding) + +AnnotationAssertion(Annotation( "GOC:ecd") "Binding to calcitonin, a peptide hormone responsible for reducing serum calcium levels by inhibiting osteoclastic bone reabsorption and promoting renal calcium excretion. It is synthesized and released by the C cells of the thyroid.") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0032841") +AnnotationAssertion(rdfs:label "calcitonin binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (response to insulin) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "ISBN:0198506732") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms.") +AnnotationAssertion(Annotation( "GOC:dos") "response to insulin stimulus") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032868") +AnnotationAssertion(rdfs:label "response to insulin") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (cellular response to insulin stimulus) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "ISBN:0198506732") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032869") +AnnotationAssertion(rdfs:label "cellular response to insulin stimulus") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (cellular response to hormone stimulus) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hormone stimulus.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032870") +AnnotationAssertion(rdfs:label "cellular response to hormone stimulus") +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of karyogamy) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of karyogamy, the creation of a single nucleus from multiple nuclei as a result of membrane fusion.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032871") +AnnotationAssertion(rdfs:label "regulation of karyogamy") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of establishment or maintenance of cell polarity) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032878") +AnnotationAssertion(rdfs:label "regulation of establishment or maintenance of cell polarity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (regulation of localization) AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of any process in which a cell, a substance, or a cellular entity is transported to, or maintained in, a specific location.") @@ -34042,8 +74716,116 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:0032879") AnnotationAssertion(rdfs:label "regulation of localization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (regulation of protein localization) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mah") Annotation( "GOC:tb") "Any process that modulates the frequency, rate or extent of any process in which a protein is transported to, or maintained in, a specific location.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/22021"^^xsd:anyURI) +AnnotationAssertion( "jl") +AnnotationAssertion( "2015-01-20T14:32:14Z") +AnnotationAssertion( "GO:1903827") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of cellular protein localisation") +AnnotationAssertion( "regulation of cellular protein localization") +AnnotationAssertion(Annotation( "GOC:mah") "regulation of protein localisation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032880") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "regulation of protein localization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of polysaccharide metabolic process) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving polysaccharides.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032881") +AnnotationAssertion(rdfs:label "regulation of polysaccharide metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of chitin metabolic process) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving chitin.") +AnnotationAssertion( "regulation of chitin metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032882") +AnnotationAssertion(rdfs:label "regulation of chitin metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of chitin biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of chitin.") +AnnotationAssertion( "regulation of chitin anabolism") +AnnotationAssertion( "regulation of chitin formation") +AnnotationAssertion( "regulation of chitin synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "regulation of chitin biosynthesis") +AnnotationAssertion( "GO:0032883") +AnnotationAssertion(rdfs:label "regulation of chitin biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of polysaccharide biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of polysaccharides.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032885") +AnnotationAssertion(rdfs:label "regulation of polysaccharide biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of microtubule-based process) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of any cellular process that depends upon or alters the microtubule cytoskeleton.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032886") +AnnotationAssertion(rdfs:label "regulation of microtubule-based process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of organic acid transport) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032890") +AnnotationAssertion(rdfs:label "regulation of organic acid transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (negative regulation of organic acid transport) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion( "down regulation of organic acid transport") +AnnotationAssertion( "down-regulation of organic acid transport") +AnnotationAssertion( "downregulation of organic acid transport") +AnnotationAssertion( "inhibition of organic acid transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032891") +AnnotationAssertion(rdfs:label "negative regulation of organic acid transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of organic acid transport) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion( "up regulation of organic acid transport") +AnnotationAssertion( "up-regulation of organic acid transport") +AnnotationAssertion( "upregulation of organic acid transport") +AnnotationAssertion( "activation of organic acid transport") +AnnotationAssertion( "stimulation of organic acid transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032892") +AnnotationAssertion(rdfs:label "positive regulation of organic acid transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + # Class: (secretion by cell) AnnotationAssertion(Annotation( "GOC:mah") "The controlled release of a substance by a cell.") @@ -34074,8 +74856,170 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0032943") AnnotationAssertion(rdfs:label "mononuclear cell proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (regulation of mononuclear cell proliferation) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that modulates the frequency, rate or extent of mononuclear cell proliferation.") +AnnotationAssertion( "regulation of PBMC proliferation") +AnnotationAssertion( "regulation of peripheral blood mononuclear cell proliferation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032944") +AnnotationAssertion(rdfs:label "regulation of mononuclear cell proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (negative regulation of mononuclear cell proliferation) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that stops, prevents, or reduces the frequency, rate or extent of mononuclear cell proliferation.") +AnnotationAssertion( "negative regulation of PBMC proliferation") +AnnotationAssertion( "negative regulation of peripheral blood mononuclear cell proliferation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032945") +AnnotationAssertion(rdfs:label "negative regulation of mononuclear cell proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of mononuclear cell proliferation) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that activates or increases the frequency, rate or extent of mononuclear cell proliferation.") +AnnotationAssertion( "up regulation of mononuclear cell proliferation") +AnnotationAssertion( "up-regulation of mononuclear cell proliferation") +AnnotationAssertion( "upregulation of mononuclear cell proliferation") +AnnotationAssertion( "activation of mononuclear cell proliferation") +AnnotationAssertion( "positive regulation of PBMC proliferation") +AnnotationAssertion( "positive regulation of peripheral blood mononuclear cell proliferation") +AnnotationAssertion( "stimulation of mononuclear cell proliferation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032946") +AnnotationAssertion(rdfs:label "positive regulation of mononuclear cell proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of actin cytoskeleton organization) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins.") +AnnotationAssertion(Annotation( "GOC:mah") "regulation of actin cytoskeleton organisation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:mah") "regulation of actin cytoskeleton organization and biogenesis") +AnnotationAssertion( "GO:0032956") +AnnotationAssertion(rdfs:label "regulation of actin cytoskeleton organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (collagen metabolic process) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%).") +AnnotationAssertion( "collagen metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032963") +AnnotationAssertion(rdfs:label "collagen metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (collagen biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%).") +AnnotationAssertion( "collagen anabolism") +AnnotationAssertion( "collagen biosynthesis") +AnnotationAssertion( "collagen formation") +AnnotationAssertion( "collagen synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032964") +AnnotationAssertion(rdfs:label "collagen biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of collagen biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals.") +AnnotationAssertion( "regulation of collagen anabolism") +AnnotationAssertion( "regulation of collagen biosynthesis") +AnnotationAssertion( "regulation of collagen formation") +AnnotationAssertion( "regulation of collagen synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032965") +AnnotationAssertion(rdfs:label "regulation of collagen biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of collagen biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals.") +AnnotationAssertion( "negative regulation of collagen anabolism") +AnnotationAssertion( "negative regulation of collagen biosynthesis") +AnnotationAssertion( "negative regulation of collagen formation") +AnnotationAssertion( "negative regulation of collagen synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032966") +AnnotationAssertion(rdfs:label "negative regulation of collagen biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of collagen biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals.") +AnnotationAssertion( "positive regulation of collagen anabolism") +AnnotationAssertion( "positive regulation of collagen biosynthesis") +AnnotationAssertion( "positive regulation of collagen formation") +AnnotationAssertion( "positive regulation of collagen synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032967") +AnnotationAssertion(rdfs:label "positive regulation of collagen biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of actin filament-based process) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of any cellular process that depends upon or alters the actin cytoskeleton.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032970") +AnnotationAssertion(rdfs:label "regulation of actin filament-based process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (amino acid export across plasma membrane) + +AnnotationAssertion(Annotation( "GOC:jl") "The directed movement of amino acids from inside of a cell, across the plasma membrane and into the extracellular region.") +AnnotationAssertion( "jl") +AnnotationAssertion( "2012-11-14T14:27:40Z") +AnnotationAssertion( "GO:0044746") +AnnotationAssertion( "amino acid export") +AnnotationAssertion( "amino acid transmembrane export") +AnnotationAssertion( "amino acid efflux") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032973") +AnnotationAssertion(rdfs:label "amino acid export across plasma membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (amino acid transmembrane export from vacuole) + +AnnotationAssertion(Annotation( "GOC:mah") "The directed movement of amino acids out of the vacuole, across the vacuolar membrane.") +AnnotationAssertion( "amino acid efflux from vacuole") +AnnotationAssertion( "vacuolar amino acid export") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032974") +AnnotationAssertion(rdfs:label "amino acid transmembrane export from vacuole") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (amino acid transmembrane import into vacuole) + +AnnotationAssertion(Annotation( "GOC:mah") "The directed movement of amino acids into the vacuole across the vacuolar membrane.") +AnnotationAssertion( "vacuolar amino acid import") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032975") +AnnotationAssertion(rdfs:label "amino acid transmembrane import into vacuole") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (keratinocyte activation) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "PMID:15737202") "A change in the morphology or behavior of a keratinocyte resulting from exposure to an activating factor such as a cellular or soluble ligand. Upon activation, keratinocytes become migratory and hyperproliferative, and produce growth factors and cytokines.") +AnnotationAssertion( ) +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032980") +AnnotationAssertion(rdfs:label "keratinocyte activation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses( ObjectSomeValuesFrom( )) + # Class: (protein-containing complex disassembly) AnnotationAssertion(Annotation( "GOC:mah") "The disaggregation of a protein-containing macromolecular complex into its constituent components.") @@ -34090,8 +75034,51 @@ AnnotationAssertion( "macromolecule complex disassembly") AnnotationAssertion( "GO:0032984") AnnotationAssertion(rdfs:label "protein-containing complex disassembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (protein-DNA complex disassembly) + +AnnotationAssertion(Annotation( "GOC:mah") "The disaggregation of a protein-DNA complex into its constituent components.") +AnnotationAssertion(Annotation( "GOC:mah") "DNA-protein complex disassembly") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032986") +AnnotationAssertion(rdfs:label "protein-DNA complex disassembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (protein-RNA complex disassembly) + +AnnotationAssertion(Annotation( "GOC:mah") "The disaggregation of a protein-RNA complex into its constituent components.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/25143"^^xsd:anyURI) +AnnotationAssertion( "RNA-protein complex disassembly") +AnnotationAssertion( "RNP complex disassembly") +AnnotationAssertion( "ribonucleoprotein complex disassembly") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032988") +AnnotationAssertion(rdfs:label "protein-RNA complex disassembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (cellular component morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mah") Annotation( "GOC:tb") "The process in which cellular structures, including whole cells or cell parts, are generated and organized.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/25496"^^xsd:anyURI) +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "cellular structure morphogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032989") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "cellular component morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (cell part morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mah") "The process in which the anatomical structures of a cell part are generated and organized.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0032990") +AnnotationAssertion(rdfs:label "cell part morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (protein-containing complex) AnnotationAssertion(Annotation( "GOC:dos") Annotation( "GOC:mah") "A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.") @@ -34114,6 +75101,174 @@ SubClassOf( ObjectSomeValuesFrom( )) DisjointClasses( ) +# Class: (protein-DNA complex) + +AnnotationAssertion(Annotation( "GOC:mah") "A macromolecular complex containing both protein and DNA molecules.") +AnnotationAssertion(Annotation( "GOC:mah") "DNA-protein complex") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0032993") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:comment "Note that this term is intended to classify complexes that have DNA as one of the members of the complex, that is, the complex does not exist if DNA is not present. Protein complexes that interact with DNA e.g. transcription factor complexes should not be classified here.") +AnnotationAssertion(rdfs:label "protein-DNA complex") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (Fc receptor complex) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") "A protein complex composed of a subunit or subunits capable of binding the Fc portion of an immunoglobulin with additional signaling components. The complex functions as a receptor for immunoglobulin.") +AnnotationAssertion( "immunoglobulin receptor complex") +AnnotationAssertion( "Fc-receptor complex") +AnnotationAssertion( "FcR complex") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0032997") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "Fc receptor complex") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (Fc-gamma receptor III complex) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") Annotation( "PMID:11244038") Annotation( "PMID:12413532") "A protein complex composed of an Fc-gamma RIII alpha chain and an Fc-epsilon RI gamma chain dimer with or without an Fc-epsilon RI beta chain and additional signaling components. The complex functions primarily as an activating receptor for IgG.") +AnnotationAssertion( "IgG receptor complex") +AnnotationAssertion( "immunoglobulin G receptor complex") +AnnotationAssertion( "FcgRIII complex") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0033001") +AnnotationAssertion(rdfs:label "Fc-gamma receptor III complex") +SubClassOf( ) + +# Class: (muscle cell proliferation) + +AnnotationAssertion(Annotation( "CL:0000187") Annotation( "GOC:mah") "The expansion of a muscle cell population by cell division.") +AnnotationAssertion( "myocyte proliferation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0033002") +AnnotationAssertion(rdfs:label "muscle cell proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (tetrapyrrole metabolic process) + +AnnotationAssertion(Annotation( "GOC:mah") "The chemical reactions and pathways involving tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next.") +AnnotationAssertion( "tetrapyrrole metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0033013") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "tetrapyrrole metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (tetrapyrrole biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:mah") "The chemical reactions and pathways leading to the formation of tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next.") +AnnotationAssertion( "tetrapyrrole anabolism") +AnnotationAssertion( "tetrapyrrole biosynthesis") +AnnotationAssertion( "tetrapyrrole formation") +AnnotationAssertion( "tetrapyrrole synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0033014") +AnnotationAssertion(rdfs:label "tetrapyrrole biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (tetrapyrrole catabolic process) + +AnnotationAssertion(Annotation( "GOC:mah") "The chemical reactions and pathways leading to the breakdown of tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next.") +AnnotationAssertion( "tetrapyrrole breakdown") +AnnotationAssertion( "tetrapyrrole catabolism") +AnnotationAssertion( "tetrapyrrole degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0033015") +AnnotationAssertion(rdfs:label "tetrapyrrole catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (myeloid cell apoptotic process) + +AnnotationAssertion(Annotation( "CL:0000763") Annotation( "GOC:add") Annotation( "GOC:mtg_apoptosis") Annotation( "PMID:11292031") Annotation( "PMID:15330259") Annotation( "PMID:17133093") "Any apoptotic process in a myeloid cell, a cell of the monocyte, granulocyte, mast cell, megakaryocyte, or erythroid lineage.") +AnnotationAssertion( "apoptosis of myeloid cells") +AnnotationAssertion( "myeloid cell apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0033028") +AnnotationAssertion(rdfs:label "myeloid cell apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of neutrophil apoptotic process) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:mtg_apoptosis") "Any process that modulates the frequency, rate, or extent of neutrophil apoptotic process.") +AnnotationAssertion( "regulation of neutrophil apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0033029") +AnnotationAssertion(rdfs:label "regulation of neutrophil apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (negative regulation of neutrophil apoptotic process) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:mtg_apoptosis") "Any process that stops, prevents, or reduces the frequency, rate, or extent of neutrophil apoptotic process.") +AnnotationAssertion( "down regulation of neutrophil apoptosis") +AnnotationAssertion( "down-regulation of neutrophil apoptosis") +AnnotationAssertion( "downregulation of neutrophil apoptosis") +AnnotationAssertion( "inhibition of neutrophil apoptosis") +AnnotationAssertion( "negative regulation of neutrophil apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0033030") +AnnotationAssertion(rdfs:label "negative regulation of neutrophil apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of neutrophil apoptotic process) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:mtg_apoptosis") "Any process that activates or increases the frequency, rate, or extent of neutrophil apoptotic process.") +AnnotationAssertion( "up regulation of neutrophil apoptosis") +AnnotationAssertion( "up-regulation of neutrophil apoptosis") +AnnotationAssertion( "upregulation of neutrophil apoptosis") +AnnotationAssertion( "activation of neutrophil apoptosis") +AnnotationAssertion( "positive regulation of neutrophil apoptosis") +AnnotationAssertion( "stimulation of neutrophil apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0033031") +AnnotationAssertion(rdfs:label "positive regulation of neutrophil apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (regulation of myeloid cell apoptotic process) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:mtg_apoptosis") "Any process that modulates the frequency, rate, or extent of myeloid cell apoptotic process.") +AnnotationAssertion( "regulation of myeloid cell apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0033032") +AnnotationAssertion(rdfs:label "regulation of myeloid cell apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of myeloid cell apoptotic process) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:mtg_apoptosis") "Any process that stops, prevents, or reduces the frequency, rate, or extent of a myeloid cell apoptotic process.") +AnnotationAssertion( "down regulation of myeloid cell apoptosis") +AnnotationAssertion( "down-regulation of myeloid cell apoptosis") +AnnotationAssertion( "downregulation of myeloid cell apoptosis") +AnnotationAssertion( "inhibition of myeloid cell apoptosis") +AnnotationAssertion( "negative regulation of myeloid cell apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0033033") +AnnotationAssertion(rdfs:label "negative regulation of myeloid cell apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of myeloid cell apoptotic process) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:mtg_apoptosis") "Any process that activates or increases the frequency, rate, or extent of myeloid cell apoptotic process.") +AnnotationAssertion( "up regulation of myeloid cell apoptosis") +AnnotationAssertion( "up-regulation of myeloid cell apoptosis") +AnnotationAssertion( "upregulation of myeloid cell apoptosis") +AnnotationAssertion( "activation of myeloid cell apoptosis") +AnnotationAssertion( "positive regulation of myeloid cell apoptosis") +AnnotationAssertion( "stimulation of myeloid cell apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0033034") +AnnotationAssertion(rdfs:label "positive regulation of myeloid cell apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (macromolecule localization) AnnotationAssertion(Annotation( "GOC:mah") "Any process in which a macromolecule is transported to, or maintained in, a specific location.") @@ -35058,6 +76213,7 @@ EquivalentClasses( ObjectIntersection # Class: (regulation of tissue remodeling) AnnotationAssertion(Annotation( "GOC:add") "Any process that modulates the frequency, rate, or extent of tissue remodeling.") +AnnotationAssertion( "regulation of tissue remodelling") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0034103") AnnotationAssertion(rdfs:label "regulation of tissue remodeling") @@ -35066,6 +76222,7 @@ EquivalentClasses( ObjectIntersection # Class: (negative regulation of tissue remodeling) AnnotationAssertion(Annotation( "GOC:add") "Any process that stops, prevents, or reduces the frequency, rate, or extent of tissue remodeling.") +AnnotationAssertion( "negative regulation of tissue remodelling") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0034104") AnnotationAssertion(rdfs:label "negative regulation of tissue remodeling") @@ -35074,6 +76231,7 @@ EquivalentClasses( ObjectIntersection # Class: (positive regulation of tissue remodeling) AnnotationAssertion(Annotation( "GOC:add") "Any process that activates or increases the frequency, rate, or extent of tissue remodeling.") +AnnotationAssertion( "positive regulation of tissue remodelling") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0034105") AnnotationAssertion(rdfs:label "positive regulation of tissue remodeling") @@ -35115,6 +76273,343 @@ AnnotationAssertion( "GO:0034220") AnnotationAssertion(rdfs:comment "Note that this term is not intended for use in annotating lateral movement within membranes.") AnnotationAssertion(rdfs:label "monoatomic ion transmembrane transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of syncytium formation by plasma membrane fusion) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that decreases the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0034242") +AnnotationAssertion(rdfs:label "negative regulation of syncytium formation by plasma membrane fusion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of amide metabolic process) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amides.") +AnnotationAssertion( "regulation of amide metabolism") +AnnotationAssertion( "regulation of cellular amide metabolic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0034248") +AnnotationAssertion(rdfs:label "regulation of amide metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of amide metabolic process) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amides.") +AnnotationAssertion( "negative regulation of amide metabolism") +AnnotationAssertion( "negative regulation of cellular amide metabolic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0034249") +AnnotationAssertion(rdfs:label "negative regulation of amide metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of amide metabolic process) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amides.") +AnnotationAssertion( "positive regulation of amide metabolism") +AnnotationAssertion( "positive regulation of cellular amide metabolic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0034250") +AnnotationAssertion(rdfs:label "positive regulation of amide metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of amide catabolic process) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of amides.") +AnnotationAssertion( "regulation of amide breakdown") +AnnotationAssertion( "regulation of amide catabolism") +AnnotationAssertion( "regulation of amide degradation") +AnnotationAssertion( "regulation of cellular amide catabolic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0034251") +AnnotationAssertion(rdfs:label "regulation of amide catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of amide catabolic process) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of amides.") +AnnotationAssertion( "negative regulation of amide breakdown") +AnnotationAssertion( "negative regulation of amide catabolism") +AnnotationAssertion( "negative regulation of cellular amide catabolic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "negative regulation of amide degradation") +AnnotationAssertion( "GO:0034252") +AnnotationAssertion(rdfs:label "negative regulation of amide catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of amide catabolic process) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of amides.") +AnnotationAssertion( "positive regulation of amide breakdown") +AnnotationAssertion( "positive regulation of amide catabolism") +AnnotationAssertion( "positive regulation of cellular amide catabolic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "positive regulation of amide degradation") +AnnotationAssertion( "GO:0034253") +AnnotationAssertion(rdfs:label "positive regulation of amide catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (response to monosaccharide) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monosaccharide stimulus.") +AnnotationAssertion(Annotation( "GOC:dos") "response to monosaccharide stimulus") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0034284") +AnnotationAssertion(rdfs:label "response to monosaccharide") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (primary alcohol metabolic process) + +AnnotationAssertion(Annotation( "GOC:mah") "The chemical reactions and pathways involving primary alcohols. A primary alcohol is any alcohol in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it.") +AnnotationAssertion( "monohydric alcohol metabolic process") +AnnotationAssertion(Annotation( "GOC:mah") "primary alcohol metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0034308") +AnnotationAssertion(rdfs:label "primary alcohol metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (primary alcohol biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:mah") "The chemical reactions and pathways resulting in the formation of primary alcohols. A primary alcohol is any alcohol in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it.") +AnnotationAssertion( "monohydric alcohol biosynthetic process") +AnnotationAssertion(Annotation( "GOC:mah") "primary alcohol anabolism") +AnnotationAssertion(Annotation( "GOC:mah") "primary alcohol biosynthesis") +AnnotationAssertion(Annotation( "GOC:mah") "primary alcohol formation") +AnnotationAssertion(Annotation( "GOC:mah") "primary alcohol synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0034309") +AnnotationAssertion(rdfs:label "primary alcohol biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (primary alcohol catabolic process) + +AnnotationAssertion(Annotation( "GOC:mah") "The chemical reactions and pathways resulting in the breakdown of primary alcohols. A primary alcohol is any alcohol in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it.") +AnnotationAssertion( "monohydric alcohol catabolic process") +AnnotationAssertion(Annotation( "GOC:mah") "primary alcohol breakdown") +AnnotationAssertion(Annotation( "GOC:mah") "primary alcohol catabolism") +AnnotationAssertion(Annotation( "GOC:mah") "primary alcohol degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0034310") +AnnotationAssertion(rdfs:label "primary alcohol catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (cell junction assembly) + +AnnotationAssertion(Annotation( "GOC:mah") "A cellular process that results in the aggregation, arrangement and bonding together of a set of components to form a cell junction.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0034329") +AnnotationAssertion(rdfs:label "cell junction assembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (cell junction organization) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:jl") Annotation( "GOC:mah") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cell junction. A cell junction is a specialized region of connection between two cells or between a cell and the extracellular matrix.") +AnnotationAssertion( "cell junction assembly and maintenance") +AnnotationAssertion(Annotation( "GOC:mah") "cell junction organisation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "cell junction biogenesis") +AnnotationAssertion( "GO:0034330") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "cell junction organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (glial cell apoptotic process) + +AnnotationAssertion(Annotation( "CL:0000125") Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:sart") "Any apoptotic process in a glial cell, a non-neuronal cell of the nervous system.") +AnnotationAssertion( "apoptosis of glia") +AnnotationAssertion( "apoptosis of glial cells") +AnnotationAssertion( "glia apoptosis") +AnnotationAssertion( "glia programmed cell death by apoptosis") +AnnotationAssertion( "glial cell programmed cell death by apoptosis") +AnnotationAssertion( "programmed cell death of glia by apoptosis") +AnnotationAssertion( "programmed cell death of glial cells by apoptosis") +AnnotationAssertion( "programmed cell death, glia") +AnnotationAssertion( "programmed cell death, glial cells") +AnnotationAssertion( "glial cell apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0034349") +AnnotationAssertion(rdfs:label "glial cell apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of glial cell apoptotic process) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:mtg_apoptosis") "Any process that modulates the frequency, rate, or extent of glial cell apoptotic process.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "regulation of glial cell apoptosis") +AnnotationAssertion( "GO:0034350") +AnnotationAssertion(rdfs:label "regulation of glial cell apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of glial cell apoptotic process) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:mtg_apoptosis") "Any process that stops, prevents, or reduces the frequency, rate, or extent of glial cell apoptotic process.") +AnnotationAssertion( "down regulation of glial cell apoptosis") +AnnotationAssertion( "down-regulation of glial cell apoptosis") +AnnotationAssertion( "downregulation of glial cell apoptosis") +AnnotationAssertion( "inhibition of glial cell apoptosis") +AnnotationAssertion( "negative regulation of glial cell apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0034351") +AnnotationAssertion(rdfs:label "negative regulation of glial cell apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of glial cell apoptotic process) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:mtg_apoptosis") "Any process that activates or increases the frequency, rate, or extent of glial cell apoptotic process.") +AnnotationAssertion( "up regulation of glial cell apoptosis") +AnnotationAssertion( "up-regulation of glial cell apoptosis") +AnnotationAssertion( "upregulation of glial cell apoptosis") +AnnotationAssertion( "activation of glial cell apoptosis") +AnnotationAssertion( "positive regulation of glial cell apoptosis") +AnnotationAssertion( "stimulation of glial cell apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0034352") +AnnotationAssertion(rdfs:label "positive regulation of glial cell apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (smooth muscle cell apoptotic process) + +AnnotationAssertion(Annotation( "CL:0000192") Annotation( "GOC:BHF") Annotation( "GOC:mah") Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:rl") "Any apoptotic process in a smooth muscle cell. Smooth muscle consists of non-striated, elongated, spindle-shaped cell found lining the digestive tract, uterus, and blood vessels.") +AnnotationAssertion( "SMC apoptosis") +AnnotationAssertion( "apoptosis of smooth muscle cells") +AnnotationAssertion( "programmed cell death of smooth muscle cells by apoptosis") +AnnotationAssertion( "programmed cell death, smooth muscle cells") +AnnotationAssertion( "smooth muscle cell programmed cell death by apoptosis") +AnnotationAssertion( "smooth muscle cell apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0034390") +AnnotationAssertion(rdfs:label "smooth muscle cell apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of smooth muscle cell apoptotic process) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:rl") "Any process that modulates the frequency, rate, or extent of smooth muscle cell apoptotic process.") +AnnotationAssertion( "regulation of SMC apoptosis") +AnnotationAssertion( "regulation of smooth muscle cell apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0034391") +AnnotationAssertion(rdfs:label "regulation of smooth muscle cell apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of smooth muscle cell apoptotic process) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:rl") "Any process that stops, prevents, or reduces the frequency, rate, or extent of smooth muscle cell apoptotic process.") +AnnotationAssertion( "down regulation of smooth muscle cell apoptosis") +AnnotationAssertion( "down-regulation of smooth muscle cell apoptosis") +AnnotationAssertion( "downregulation of smooth muscle cell apoptosis") +AnnotationAssertion( "negative regulation of SMC apoptosis") +AnnotationAssertion( "inhibition of smooth muscle cell apoptosis") +AnnotationAssertion( "negative regulation of smooth muscle cell apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0034392") +AnnotationAssertion(rdfs:label "negative regulation of smooth muscle cell apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of smooth muscle cell apoptotic process) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:rl") "Any process that activates or increases the frequency, rate, or extent of smooth muscle cell apoptotic process.") +AnnotationAssertion( "positive regulation of SMC apoptosis") +AnnotationAssertion( "up regulation of smooth muscle cell apoptosis") +AnnotationAssertion( "up-regulation of smooth muscle cell apoptosis") +AnnotationAssertion( "upregulation of smooth muscle cell apoptosis") +AnnotationAssertion( "activation of smooth muscle cell apoptosis") +AnnotationAssertion( "positive regulation of smooth muscle cell apoptosis") +AnnotationAssertion( "stimulation of smooth muscle cell apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0034393") +AnnotationAssertion(rdfs:label "positive regulation of smooth muscle cell apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (nucleobase-containing small molecule biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:mah") "The chemical reactions and pathways resulting in the formation of a nucleobase-containing small molecule: a nucleobase, a nucleoside, or a nucleotide.") +AnnotationAssertion( "nucleobase, nucleoside and nucleotide anabolism") +AnnotationAssertion( "nucleobase, nucleoside and nucleotide biosynthesis") +AnnotationAssertion( "nucleobase, nucleoside and nucleotide formation") +AnnotationAssertion( "nucleobase, nucleoside and nucleotide synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0034404") +AnnotationAssertion(rdfs:label "nucleobase-containing small molecule biosynthetic process") +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (tectobulbar tract morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dsf") Annotation( "PMID:15065115") Annotation( "PMID:17507550") Annotation( "PMID:8038988") "Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the optic tectum towards target cells in the premotor reticulospinal system in the hindbrain.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0034429") +AnnotationAssertion(rdfs:label "tectobulbar tract morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (glycoprotein transport) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mah") Annotation( "GOC:rl") "The directed movement of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0034436") +AnnotationAssertion(rdfs:label "glycoprotein transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (vacuolar transmembrane transport) + +AnnotationAssertion(Annotation( "GOC:mah") "The process in which a solute is transported from one side of the vacuolar membrane to the other.") +AnnotationAssertion( "vacuolar membrane transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0034486") +AnnotationAssertion(rdfs:comment "Note that this term is not intended for use in annotating lateral movement within membranes.") +AnnotationAssertion(rdfs:label "vacuolar transmembrane transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (vacuolar amino acid transmembrane transport) + +AnnotationAssertion(Annotation( "GOC:mah") "The process in which an amino acid is transported from one side of the vacuolar membrane to the other.") +AnnotationAssertion( "vacuolar amino acid membrane transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0034487") +AnnotationAssertion(rdfs:comment "Note that this term is not intended for use in annotating lateral movement within membranes.") +AnnotationAssertion(rdfs:label "vacuolar amino acid transmembrane transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (protein localization to chromosome) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process in which a protein is transported to, or maintained at, a specific location on a chromosome.") +AnnotationAssertion(Annotation( "GOC:mah") "protein localisation to chromosome") +AnnotationAssertion( "condensin localization to chromosome") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0034502") +AnnotationAssertion(rdfs:label "protein localization to chromosome") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (protein localization to nucleus) + +AnnotationAssertion(Annotation( "GOC:ecd") "A process in which a protein transports or maintains the localization of another protein to the nucleus.") +AnnotationAssertion( "2012-11-07T15:45:54Z") +AnnotationAssertion( "GO:0044744") +AnnotationAssertion(Annotation( "GOC:mah") "protein localisation to nucleus") +AnnotationAssertion( "protein localization in cell nucleus") +AnnotationAssertion(Annotation( "GOC:mah") "protein localization in nucleus") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "protein targeting to nucleus") +AnnotationAssertion( "GO:0034504") +AnnotationAssertion(rdfs:label "protein localization to nucleus") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (tooth mineralization) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "MP:0002817") Annotation( "MSH:D014074") "The process in which calcium salts are deposited into calcareous tooth structures such as dental enamel, dentin and cementum.") +AnnotationAssertion( "tooth calcification") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0034505") +AnnotationAssertion(rdfs:label "tooth mineralization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) # Class: (cellular nitrogen compound metabolic process) @@ -35127,6 +76622,503 @@ AnnotationAssertion(rdfs:label "cell SubClassOf( ) SubClassOf( ) +# Class: (nucleobase-containing compound biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:mah") "The chemical reactions and pathways resulting in the formation of nucleobases, nucleosides, nucleotides and nucleic acids.") +AnnotationAssertion( "nucleobase, nucleoside, nucleotide and nucleic acid anabolism") +AnnotationAssertion( "nucleobase, nucleoside, nucleotide and nucleic acid biosynthesis") +AnnotationAssertion( "nucleobase, nucleoside, nucleotide and nucleic acid formation") +AnnotationAssertion( "nucleobase, nucleoside, nucleotide and nucleic acid synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0034654") +AnnotationAssertion(rdfs:label "nucleobase-containing compound biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (nucleobase-containing compound catabolic process) + +AnnotationAssertion(Annotation( "GOC:mah") "The chemical reactions and pathways resulting in the breakdown of nucleobases, nucleosides, nucleotides and nucleic acids.") +AnnotationAssertion( "nucleobase, nucleoside, nucleotide and nucleic acid breakdown") +AnnotationAssertion( "nucleobase, nucleoside, nucleotide and nucleic acid catabolism") +AnnotationAssertion( "nucleobase, nucleoside, nucleotide and nucleic acid degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "nucleobase, nucleoside, nucleotide and nucleic acid catabolic process") +AnnotationAssertion( "GO:0034655") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "nucleobase-containing compound catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (nucleobase-containing small molecule catabolic process) + +AnnotationAssertion(Annotation( "GOC:mah") "The chemical reactions and pathways resulting in the breakdown of a nucleobase-containing small molecule: a nucleobase, a nucleoside, or a nucleotide.") +AnnotationAssertion( "nucleobase, nucleoside and nucleotide breakdown") +AnnotationAssertion( "nucleobase, nucleoside and nucleotide catabolism") +AnnotationAssertion( "nucleobase, nucleoside and nucleotide degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0034656") +AnnotationAssertion(rdfs:label "nucleobase-containing small molecule catabolic process") +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (anterior/posterior pattern specification involved in pronephros development) + +AnnotationAssertion(Annotation( "GOC:mah") "The developmental process that results in the creation of defined areas or spaces within the pronephros along the anterior/posterior axis to which cells respond and eventually are instructed to differentiate.") +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "anterior/posterior pattern specification involved in pronephric kidney development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0034672") +AnnotationAssertion(rdfs:label "anterior/posterior pattern specification involved in pronephros development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (iron ion transmembrane transport) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "PMID:11390404") "A process in which an iron ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.") +AnnotationAssertion( "vw") +AnnotationAssertion( "2015-02-06T11:29:22Z") +AnnotationAssertion( "GO:0000040") +AnnotationAssertion( "GO:0006827") +AnnotationAssertion( "GO:0061839") +AnnotationAssertion( "GO:1903874") +AnnotationAssertion( "iron ion membrane transport") +AnnotationAssertion( "transmembrane iron transport") +AnnotationAssertion( "ferrous ion transmembrane transport") +AnnotationAssertion( "ferrous iron transmembrane transport") +AnnotationAssertion( "high affinity ferrous ion transmembrane transport") +AnnotationAssertion( "high affinity iron ion transport") +AnnotationAssertion( "high-affinity ferrous ion transmembrane transport") +AnnotationAssertion( "high-affinity iron ion transmembrane transport") +AnnotationAssertion( "high-affinity iron ion transport") +AnnotationAssertion( "iron(2+) transmembrane transport") +AnnotationAssertion( "low affinity iron ion transport") +AnnotationAssertion( "low-affinity iron ion transmembrane transport") +AnnotationAssertion( "low-affinity iron ion transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0034755") +AnnotationAssertion(rdfs:comment "Note that this term is not intended for use in annotating lateral movement within membranes.") +AnnotationAssertion(rdfs:label "iron ion transmembrane transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of iron ion transport) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the directed movement of iron ions (Fe) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2012-04-18T04:00:14Z") +AnnotationAssertion( "GO:1900390") +AnnotationAssertion( "regulation of Fe transport") +AnnotationAssertion( "regulation of iron transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of iron import") +AnnotationAssertion( "regulation of iron ion import") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0034756") +AnnotationAssertion(rdfs:label "regulation of iron ion transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of iron ion transport) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of iron ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion( "down regulation of iron ion transport") +AnnotationAssertion( "down-regulation of iron ion transport") +AnnotationAssertion( "downregulation of iron ion transport") +AnnotationAssertion( "negative regulation of iron transport") +AnnotationAssertion( "inhibition of iron ion transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0034757") +AnnotationAssertion(rdfs:label "negative regulation of iron ion transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of iron ion transport) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of the directed movement of iron ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion( "positive regulation of iron transport") +AnnotationAssertion( "up regulation of iron ion transport") +AnnotationAssertion( "up-regulation of iron ion transport") +AnnotationAssertion( "upregulation of iron ion transport") +AnnotationAssertion( "activation of iron ion transport") +AnnotationAssertion( "stimulation of iron ion transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0034758") +AnnotationAssertion(rdfs:label "positive regulation of iron ion transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of iron ion transmembrane transport) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the directed movement of iron ions (Fe) from one side of a membrane to the other by means of some agent such as a transporter or pore.") +AnnotationAssertion( "regulation of iron ion membrane transport") +AnnotationAssertion( "regulation of transmembrane Fe transport") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "regulation of transmembrane iron ion transport") +AnnotationAssertion( "regulation of transmembrane iron transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0034759") +AnnotationAssertion(rdfs:label "regulation of iron ion transmembrane transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of iron ion transmembrane transport) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of iron ions from one side of a membrane to the other by means of some agent such as a transporter or pore.") +AnnotationAssertion( "down regulation of transmembrane iron ion transport") +AnnotationAssertion( "down-regulation of transmembrane iron ion transport") +AnnotationAssertion( "downregulation of transmembrane iron ion transport") +AnnotationAssertion( "negative regulation of iron ion membrane transport") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "negative regulation of transmembrane iron ion transport") +AnnotationAssertion( "negative regulation of transmembrane iron transport") +AnnotationAssertion( "inhibition of transmembrane iron ion transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0034760") +AnnotationAssertion(rdfs:label "negative regulation of iron ion transmembrane transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of iron ion transmembrane transport) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of the directed movement of iron ions from one side of a membrane to the other by means of some agent such as a transporter or pore.") +AnnotationAssertion( "positive regulation of iron ion membrane transport") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "positive regulation of transmembrane iron ion transport") +AnnotationAssertion( "positive regulation of transmembrane iron transport") +AnnotationAssertion( "up regulation of transmembrane iron ion transport") +AnnotationAssertion( "up-regulation of transmembrane iron ion transport") +AnnotationAssertion( "upregulation of transmembrane iron ion transport") +AnnotationAssertion( "activation of transmembrane iron ion transport") +AnnotationAssertion( "stimulation of transmembrane iron ion transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0034761") +AnnotationAssertion(rdfs:label "positive regulation of iron ion transmembrane transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of transmembrane transport) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other.") +AnnotationAssertion( "regulation of membrane transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0034762") +AnnotationAssertion(rdfs:label "regulation of transmembrane transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of transmembrane transport) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other.") +AnnotationAssertion( "down regulation of transmembrane transport") +AnnotationAssertion( "down-regulation of transmembrane transport") +AnnotationAssertion( "downregulation of transmembrane transport") +AnnotationAssertion( "negative regulation of membrane transport") +AnnotationAssertion( "inhibition of transmembrane transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0034763") +AnnotationAssertion(rdfs:label "negative regulation of transmembrane transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of transmembrane transport) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other.") +AnnotationAssertion( "positive regulation of membrane transport") +AnnotationAssertion( "up regulation of transmembrane transport") +AnnotationAssertion( "up-regulation of transmembrane transport") +AnnotationAssertion( "upregulation of transmembrane transport") +AnnotationAssertion( "activation of transmembrane transport") +AnnotationAssertion( "stimulation of transmembrane transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0034764") +AnnotationAssertion(rdfs:label "positive regulation of transmembrane transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of monoatomic ion transmembrane transport) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other.") +AnnotationAssertion( "regulation of ion transmembrane transport") +AnnotationAssertion( "regulation of ion membrane transport") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "regulation of transmembrane ion transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0034765") +AnnotationAssertion(rdfs:label "regulation of monoatomic ion transmembrane transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of monoatomic ion transmembrane transport) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other.") +AnnotationAssertion( "negative regulation of ion transmembrane transport") +AnnotationAssertion( "down regulation of transmembrane ion transport") +AnnotationAssertion( "down-regulation of transmembrane ion transport") +AnnotationAssertion( "downregulation of transmembrane ion transport") +AnnotationAssertion( "negative regulation of ion membrane transport") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "negative regulation of transmembrane ion transport") +AnnotationAssertion( "inhibition of transmembrane ion transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0034766") +AnnotationAssertion(rdfs:label "negative regulation of monoatomic ion transmembrane transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of monoatomic ion transmembrane transport) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other.") +AnnotationAssertion( "positive regulation of ion transmembrane transport") +AnnotationAssertion( "positive regulation of ion membrane transport") +AnnotationAssertion( "positive regulation of transmembrane ion transport") +AnnotationAssertion( "up regulation of transmembrane ion transport") +AnnotationAssertion( "up-regulation of transmembrane ion transport") +AnnotationAssertion( "upregulation of transmembrane ion transport") +AnnotationAssertion( "activation of transmembrane ion transport") +AnnotationAssertion( "stimulation of transmembrane ion transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0034767") +AnnotationAssertion(rdfs:label "positive regulation of monoatomic ion transmembrane transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (basement membrane disassembly) + +AnnotationAssertion(Annotation( "GOC:sart") Annotation( "PMID:17301221") "The controlled breakdown of the basement membrane in the context of a normal process such as imaginal disc eversion.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-08-13T11:27:24Z") +AnnotationAssertion( "GO:0060881") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "basal lamina disassembly") +AnnotationAssertion( "GO:0034769") +AnnotationAssertion(rdfs:comment "Note that this term has no relationship to 'membrane disassembly ; GO:0030397' because the basement membrane is not a lipid bilayer.") +AnnotationAssertion(rdfs:label "basement membrane disassembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (response to histamine) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mah") Annotation( "GOC:vk") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a histamine stimulus. Histamine, the biogenic amine 2-(1H-imidazol-4-yl)ethanamine, is involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter.") +AnnotationAssertion( "response to histamine stimulus") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0034776") +AnnotationAssertion(rdfs:label "response to histamine") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (somatic stem cell population maintenance) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "ISBN:0582227089") "Any process by which an organism retains a population of somatic stem cells, undifferentiated cells in the embryo or adult which can undergo unlimited division and give rise to cell types of the body other than those of the germ-line.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035019") +AnnotationAssertion(rdfs:label "somatic stem cell population maintenance") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (male pronucleus assembly) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "PMID:11735001") "The conversion at fertilization of the inactive sperm nucleus into a male pronucleus with its chromosomes processed for the first zygotic division.") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") "male pronucleus formation") +AnnotationAssertion( "GO:0035039") +AnnotationAssertion(rdfs:label "male pronucleus assembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (sperm nuclear envelope removal) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "PMID:11735001") "Removal of the sperm nuclear envelope, allowing entry of maternal factors into the sperm nucleus.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035040") +AnnotationAssertion(rdfs:label "sperm nuclear envelope removal") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (sperm plasma membrane disassembly) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "ISBN:0879694238") "The gradual disintegration of the sperm plasma membrane following insemination. This process is seen in Drosophila after entry of the entire sperm, surrounded by its plasma membrane, into the egg.") +AnnotationAssertion( "sperm plasma membrane breakdown") +AnnotationAssertion( "sperm plasma membrane catabolism") +AnnotationAssertion( "sperm plasma membrane degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035045") +AnnotationAssertion(rdfs:label "sperm plasma membrane disassembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (embryonic heart tube development) + +AnnotationAssertion(Annotation( "GOC:go_curators") "The process whose specific outcome is the progression of the embryonic heart tube over time, from its formation to the mature structure. The heart tube forms as the heart rudiment from the heart field.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035050") +AnnotationAssertion(rdfs:label "embryonic heart tube development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cardiocyte differentiation) + +AnnotationAssertion(Annotation( "GOC:bf") "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell that will form part of the cardiac organ of an individual.") +AnnotationAssertion( "cardiac cell differentiation") +AnnotationAssertion( "heart cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035051") +AnnotationAssertion(rdfs:label "cardiocyte differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (axoneme assembly) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:cilia") Annotation( "GOC:jl") Annotation( "ISBN:0815316194") "The assembly and organization of an axoneme, the bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements.") +AnnotationAssertion( "GO:0035083") +AnnotationAssertion( "GO:0035084") +AnnotationAssertion( "ciliary axoneme assembly") +AnnotationAssertion( "cilium axoneme assembly") +AnnotationAssertion( "flagellar axoneme assembly") +AnnotationAssertion( "flagellum axoneme assembly") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:mah") "axoneme biogenesis") +AnnotationAssertion(Annotation( "GOC:mah") "cilium axoneme biogenesis") +AnnotationAssertion( "GO:0035082") +AnnotationAssertion(rdfs:comment "Note that cilia and eukaryotic flagella are deemed to be equivalent.") +AnnotationAssertion(rdfs:label "axoneme assembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (hemocyte migration) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:mtg_sensu") Annotation( "PMID:12885551") "The directed movement of a hemocyte within the embryo. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. In Drosophila, embryonic hemocytes originate from the head mesoderm as a cluster of cells. The cluster splits into two and one group of cells crosses the amnioserosa. Both populations then spread toward the middle of the embryo and then disperse evenly throughout the embryo.") +AnnotationAssertion( "arthropod blood cell migration") +AnnotationAssertion( "hemocyte cell migration") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035099") +AnnotationAssertion(rdfs:label "hemocyte migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectAllValuesFrom( )) + +# Class: (appendage morphogenesis) + +AnnotationAssertion(Annotation( "ISBN:0582227089") "The process in which the anatomical structures of appendages are generated and organized. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035107") +AnnotationAssertion(rdfs:label "appendage morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (limb morphogenesis) + +AnnotationAssertion(Annotation( "UBERON:0002101") "The process in which the anatomical structures of a limb are generated and organized. A limb is a paired appendage of a tetrapod used for locomotion or grasping.") +AnnotationAssertion(Annotation( "GOC:dph") "limb bud morphogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035108") +AnnotationAssertion(rdfs:label "limb morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (genitalia morphogenesis) + +AnnotationAssertion(Annotation( "GOC:bf") "The process in which the anatomical structures of genitalia are generated and organized. The genitalia are the organs of reproduction or generation, external and internal.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "genital morphogenesis") +AnnotationAssertion( "GO:0035112") +AnnotationAssertion(rdfs:label "genitalia morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (imaginal disc-derived appendage morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_sensu") Annotation( "ISBN:0582227089") "The process in which the anatomical structures of appendages are generated and organized. An appendage is an organ or part that is attached to the trunk of an organism.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035114") +AnnotationAssertion(rdfs:label "imaginal disc-derived appendage morphogenesis") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (post-embryonic appendage morphogenesis) + +AnnotationAssertion(Annotation( "ISBN:0582227089") "The process, occurring after embryonic development, by which the anatomical structures of an appendage are generated and organized. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035120") +AnnotationAssertion(rdfs:label "post-embryonic appendage morphogenesis") +SubClassOf( ) +SubClassOf( ) + +# Class: (forelimb morphogenesis) + +AnnotationAssertion(Annotation( "GOC:go_curators") "The process in which the anatomical structures of the forelimb are generated and organized. The forelimbs are the front limbs of an animal, e.g. the arms of a human.") +AnnotationAssertion( "GO:0035140") +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:cjm") "arm morphogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035136") +AnnotationAssertion(rdfs:label "forelimb morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (hindlimb morphogenesis) + +AnnotationAssertion(Annotation( "GOC:go_curators") "The process in which the anatomical structures of the hindlimb are generated and organized.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035137") +AnnotationAssertion(rdfs:label "hindlimb morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (pectoral fin morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dgh") "The process in which the anatomical structures of the pectoral fin are generated and organized. Pectoral fins are bilaterally paired fins mounted laterally and located behind the gill covers of fish. These fins are used for lateral mobility and propulsion.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035138") +AnnotationAssertion(rdfs:label "pectoral fin morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (pelvic fin morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dgh") "The process in which the anatomical structures of the pelvic fin are generated and organized. Pelvic fins are bilaterally paired fins mounted in a ventral-lateral position on most fish. These fins are used primarily for lateral mobility and propulsion.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035139") +AnnotationAssertion(rdfs:label "pelvic fin morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (medial fin morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dgh") "The process in which the anatomical structures of the medial fin are generated and organized. A medial fin is an unpaired fin of fish, usually located dorsomedially or ventromedially and primarily used for stability while swimming.") +AnnotationAssertion( "median fin morphogenesis") +AnnotationAssertion( "unpaired fin morphogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035141") +AnnotationAssertion(rdfs:label "medial fin morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (dorsal fin morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dgh") "The process in which the anatomical structures of the dorsal fin are generated and organized. A dorsal fin is an unpaired medial fin on the dorsal aspect of fish that provides lateral stability while swimming. Generally fish have one or two dorsal fins.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035142") +AnnotationAssertion(rdfs:label "dorsal fin morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (caudal fin morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dgh") "The process in which the anatomical structures of the caudal fin are generated and organized. A caudal fin is an unpaired medial fin mounted at the caudal end of the fish, and is the main fin used for propulsion.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035143") +AnnotationAssertion(rdfs:label "caudal fin morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (anal fin morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dgh") "The process in which the anatomical structures of the anal fin are generated and organized. An anal fin is an unpaired medial fin on the ventral aspect near the caudal end of a fish, which provides lateral stability while swimming.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035144") +AnnotationAssertion(rdfs:label "anal fin morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (tube formation) AnnotationAssertion(Annotation( "GOC:bf") "Creation of the central hole of a tube in an anatomical structure through which gases and/or liquids flow.") @@ -35135,10 +77127,36 @@ AnnotationAssertion( "GOC:dph") Annotation( "GOC:mah") "lumen formation in an anatomical structure") AnnotationAssertion( "GO:0035148") AnnotationAssertion(rdfs:label "tube formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (embryonic hemopoiesis) + +AnnotationAssertion(Annotation( "GOC:bf") "The stages of blood cell formation that take place within the embryo.") +AnnotationAssertion( "embryonic haematopoiesis") +AnnotationAssertion( "embryonic haemopoiesis") +AnnotationAssertion( "embryonic hematopoiesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035162") +AnnotationAssertion(rdfs:label "embryonic hemopoiesis") +SubClassOf( ) +SubClassOf( ) + +# Class: (hemocyte proliferation) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:mtg_sensu") "The multiplication or reproduction of hemocytes, resulting in the expansion of the cell population. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen.") +AnnotationAssertion( "arthropod blood cell proliferation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035172") +AnnotationAssertion(rdfs:label "hemocyte proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectAllValuesFrom( )) + # Class: (hatching) AnnotationAssertion(Annotation( "GOC:dgh") Annotation( "GOC:isa_complete") Annotation( "ISBN:0198612001") "The emergence of an immature organism from a protective structure.") @@ -35148,26 +77166,140 @@ AnnotationAssertion(rdfs:label "hatc SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (syncytial nuclear migration) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "ISBN:0879694238") Annotation( "PMID:8314839") "The directed movement of nuclei within the syncytial embryo of insects. These precise temporal and spatial patterns of nuclear movement are coordinated with mitotic divisons and are required during blastoderm formation to reposition dividing nuclei from the interior of the syncytial embryo to the cortex.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035190") +AnnotationAssertion(rdfs:label "syncytial nuclear migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (regulation of hemocyte proliferation) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:mtg_sensu") "Any process that modulates the frequency, rate or extent of hemocyte proliferation. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. An example of this is found in Drosophila melanogaster.") +AnnotationAssertion( "regulation of arthropod blood cell proliferation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035206") +AnnotationAssertion(rdfs:label "regulation of hemocyte proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of hemocyte proliferation) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:mtg_sensu") "Any process that stops, prevents or reduces the rate or extent of hemocyte proliferation. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. An example of this is found in Drosophila melanogaster.") +AnnotationAssertion( "down regulation of hemocyte proliferation") +AnnotationAssertion( "down-regulation of hemocyte proliferation") +AnnotationAssertion( "downregulation of hemocyte proliferation") +AnnotationAssertion( "negative regulation of arthropod blood cell proliferation") +AnnotationAssertion( "inhibition of hemocyte proliferation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035207") +AnnotationAssertion(rdfs:label "negative regulation of hemocyte proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectAllValuesFrom( )) + +# Class: (positive regulation of hemocyte proliferation) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:mtg_sensu") "Any process that activates or increases the rate or extent of hemocyte proliferation. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) that are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. An example of this process is found in Drosophila melanogaster.") +AnnotationAssertion( "positive regulation of arthropod blood cell proliferation") +AnnotationAssertion( "up regulation of hemocyte proliferation") +AnnotationAssertion( "up-regulation of hemocyte proliferation") +AnnotationAssertion( "upregulation of hemocyte proliferation") +AnnotationAssertion( "activation of hemocyte proliferation") +AnnotationAssertion( "stimulation of hemocyte proliferation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035208") +AnnotationAssertion(rdfs:label "positive regulation of hemocyte proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (pupal development) AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:mtg_sensu") "The process whose specific outcome is the progression of the pupa over time, from its formation to the mature structure. The pupa is a dormant life stage interposed between the larval and the adult stages in insects that undergo a complete metamorphosis.") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0035209") AnnotationAssertion(rdfs:label "pupal development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (spermathecum morphogenesis) + +AnnotationAssertion(Annotation( "PMID:12679097") "The process in which the anatomical structures of a spermathecum, a sperm storage organ, are generated and organized. Paired spermathecae lie at the anterior end of the insect uterus on the dorsal side. Each spermatheca consists of an oval shaped capsule, connected to the uterus by a spermathecal stalk.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035211") +AnnotationAssertion(rdfs:comment "See also the fly_anatomy.ontology term 'spermathecum ; FBbt:00004921'.") +AnnotationAssertion(rdfs:label "spermathecum morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (eye-antennal disc development) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "ISBN:0879694238") "Progression of the eye-antennal imaginal disc over time, from its initial formation through to its metamorphosis to form adult structures including the eye, antenna, head capsule and maxillary palps.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035214") +AnnotationAssertion(rdfs:label "eye-antennal disc development") +SubClassOf( ) + +# Class: (haltere disc development) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "ISBN:0879694238") "Progression of the haltere imaginal disc over time, from its initial formation through to its metamorphosis to form the adult capitellum, pedicel, haltere sclerite, metathoracic spiracle and metanotum.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035216") +AnnotationAssertion(rdfs:label "haltere disc development") +SubClassOf( ) + +# Class: (leg disc development) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "ISBN:0879694238") "Progression of the leg imaginal disc over time, from its initial formation through to its metamorphosis to form adult structures including the leg, coxa and ventral thoracic pleura.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035218") +AnnotationAssertion(rdfs:label "leg disc development") +SubClassOf( ) + +# Class: (wing disc development) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "ISBN:0879694238") "Progression of the wing disc over time, from its initial formation through to its metamorphosis to form adult structures including the wing hinge, wing blade and pleura.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035220") +AnnotationAssertion(rdfs:label "wing disc development") +SubClassOf( ) + +# Class: (ectopic germ cell programmed cell death) + +AnnotationAssertion(Annotation( "PMID:12814944") "Programmed cell death of an errant germ line cell that is outside the normal migratory path or ectopic to the gonad. This is an important mechanism of regulating germ cell survival within the embryo.") +AnnotationAssertion( "programmed cell death of ectopic germ cells") +AnnotationAssertion( "programmed cell death, ectopic germ cells") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035234") +AnnotationAssertion(rdfs:label "ectopic germ cell programmed cell death") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + # Class: (tube morphogenesis) AnnotationAssertion(Annotation( "GOC:bf") Annotation( "PMID:14624839") "The process in which the anatomical structures of a tube are generated and organized. Epithelial and endothelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues, with tube shape and organization varying from the single-celled excretory organ in Caenorhabditis elegans to the branching trees of the mammalian kidney and insect tracheal system.") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0035239") AnnotationAssertion(rdfs:label "tube morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (dopamine binding) + +AnnotationAssertion(Annotation( "ISBN:0198506732") "Binding to dopamine, a catecholamine neurotransmitter formed by aromatic-L-amino-acid decarboxylase from 3,4-dihydroxy-L-phenylalanine.") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0035240") +AnnotationAssertion(rdfs:label "dopamine binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (synaptic transmission, glutamatergic) AnnotationAssertion(Annotation( "GOC:dos") "The vesicular release of glutamate from a presynapse, across a chemical synapse, the subsequent activation of glutamate receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.") @@ -35177,15 +77309,576 @@ AnnotationAssertion( "synaptic transmission, glutamatergic") SubClassOf( ) +# Class: (internal genitalia morphogenesis) + +AnnotationAssertion(Annotation( "http://www.ndif.org/Terms/genitalia.html") "The process in which the anatomical structures of the internal genitalia are generated and organized. The internal genitalia are the internal sex organs such as the uterine tube, the uterus and the vagina in female mammals, and the testis, seminal vesicle, ejaculatory duct and prostate in male mammals.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035260") +AnnotationAssertion(rdfs:label "internal genitalia morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (external genitalia morphogenesis) + +AnnotationAssertion(Annotation( "http://www.ndif.org/Terms/genitalia.html") "The process in which the anatomical structures of the external genitalia are generated and organized. The external genitalia are the outer sex organs, such as the penis or vulva in mammals.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035261") +AnnotationAssertion(rdfs:label "external genitalia morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (gonad morphogenesis) + +AnnotationAssertion(Annotation( "ISBN:0198612001") "The process in which the anatomical structures of the gonads are generated and organized. A gonad is an animal organ producing gametes, e.g. the testes or the ovary in mammals.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035262") +AnnotationAssertion(rdfs:label "gonad morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (multicellular organism growth) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:curators") Annotation( "GOC:dph") Annotation( "GOC:tb") "The increase in size or mass of an entire multicellular organism, as opposed to cell growth.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "body growth") +AnnotationAssertion( "GO:0035264") +AnnotationAssertion(rdfs:label "multicellular organism growth") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (organ growth) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "ISBN:0471245208") Annotation( "ISBN:0721662544") "The increase in size or mass of an organ. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that function together as to perform a specific function.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035265") +AnnotationAssertion(rdfs:label "organ growth") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (endocrine system development) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "Wikipedia:Development_of_the_endocrine_system") "Progression of the endocrine system over time, from its formation to a mature structure. The endocrine system is a system of hormones and ductless glands, where the glands release hormones directly into the blood, lymph or other intercellular fluid, and the hormones circulate within the body to affect distant organs. The major glands that make up the human endocrine system are the hypothalamus, pituitary, thyroid, parathryoids, adrenals, pineal body, and the reproductive glands which include the ovaries and testes.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035270") +AnnotationAssertion(rdfs:label "endocrine system development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (exocrine system development) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "Wikipedia:Exocrine_gland") "Progression of the exocrine system over time, from its formation to a mature structure. The exocrine system is a system of hormones and glands, where the glands secrete straight to a target site via ducts or tubes. The human exocrine system includes the salivary glands, sweat glands and many glands of the digestive system.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035272") +AnnotationAssertion(rdfs:label "exocrine system development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (segmentation) + +AnnotationAssertion(Annotation( "PMID:10611687") Annotation( "PMID:9706689") "The regionalization process that divides an organism or part of an organism into a series of semi-repetitive parts, or segments, often arranged along a longitudinal axis.") +AnnotationAssertion( "Wikipedia:Segmentation_(biology)") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035282") +AnnotationAssertion(rdfs:label "segmentation") +SubClassOf( ) + +# Class: (trunk segmentation) + +AnnotationAssertion(Annotation( "PMID:1360402") "Partitioning of the blastoderm embryo into trunk segmental units. In Drosophila, the trunk segments include thoracic segments and abdominal segments A1 to A8.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035290") +AnnotationAssertion(rdfs:label "trunk segmentation") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (tube development) AnnotationAssertion(Annotation( "PMID:12526790") "The process whose specific outcome is the progression of a tube over time, from its initial formation to a mature structure. Epithelial and endothelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues including lung and trachea, kidney, the mammary gland, the vascular system and the gastrointestinal and urinary-genital tracts.") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0035295") AnnotationAssertion(rdfs:label "tube development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (hair cell differentiation) + +AnnotationAssertion(Annotation( "GOC:bf") "The process in which a relatively unspecialized cell acquires specialized features of a hair cell.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035315") +AnnotationAssertion(rdfs:label "hair cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (non-sensory hair organization) + +AnnotationAssertion(Annotation( "GOC:mtg_sensu") Annotation( "PMID:11064425") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of non-sensory hairs. These hairs are polarized cellular extensions that cover much of the insect epidermis.") +AnnotationAssertion( "trichome organisation") +AnnotationAssertion( "trichome organization and biogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:mah") "non-sensory hair organization and biogenesis") +AnnotationAssertion( "GO:0035316") +AnnotationAssertion(rdfs:comment "See also the fly_anatomy.ontology term 'trichome ; FBbt:00004979'.") +AnnotationAssertion(rdfs:label "non-sensory hair organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectAllValuesFrom( )) + +# Class: (imaginal disc-derived wing hair organization) + +AnnotationAssertion(Annotation( "GOC:mtg_sensu") Annotation( "PMID:11064425") Annotation( "PMID:12540853") "A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of an imaginal disc-derived wing hair. A wing hair is an actin-rich, polarized, non-sensory apical projection that protrudes from each of the approximately 30,000 wing epithelial cells. An example of this is found in Drosophila melanogaster.") +AnnotationAssertion( "wing hair organisation") +AnnotationAssertion( "wing trichome organization and biogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:mah") "imaginal disc-derived wing hair organization and biogenesis") +AnnotationAssertion(Annotation( "GOC:mah") "wing hair organization and biogenesis") +AnnotationAssertion( "GO:0035317") +AnnotationAssertion(rdfs:comment "See also the fly_anatomy.ontology term 'wing hair ; FBbt:00004340'.") +AnnotationAssertion(rdfs:label "imaginal disc-derived wing hair organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (mesenchymal cell migration involved in limb bud formation) + +AnnotationAssertion(Annotation( "GOC:dgh") "The orderly movement of a mesenchymal cell from one site to another that will contribute to the formation of a limb bud.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2010-02-24T02:05:14Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035322") +AnnotationAssertion(rdfs:label "mesenchymal cell migration involved in limb bud formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (pre-B cell receptor complex) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781765196") Annotation( "PMID:16464608") Annotation( "PMID:17306522") "An immunoglobulin-like complex that is present in at least the plasma membrane of pre-B cells, and that is composed of two identical immunoglobulin heavy chains and two surrogate light chains, each composed of the lambda-5 and VpreB proteins, and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2010-03-11T10:46:10Z") +AnnotationAssertion( "pre-BCR") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0035369") +AnnotationAssertion(rdfs:comment "Despite its name, the pre-BCR is not a receptor complex, as it appears to provide a low level of signal not dependent on a ligand, but rather simply on correct assembly of the complex as a measure for correct Ig heavy chain recombination and folding. A significant proportion of pre-BCR complexes fail to reach the cell surface, and in some cases may provide their signaling function from the trans-Golgi network or lysosome.") +AnnotationAssertion(rdfs:label "pre-B cell receptor complex") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (protein localization to microtubule) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:lb") "A process in which a protein is transported to, or maintained at, a microtubule.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2010-03-11T11:00:56Z") +AnnotationAssertion(Annotation( "GOC:mah") "protein localisation to microtubule") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035372") +AnnotationAssertion(rdfs:label "protein localization to microtubule") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (chondroitin sulfate binding) + +AnnotationAssertion(Annotation( "GOC:kmv") Annotation( "ISBN:0198506732") "Binding to chondroitin sulfate, a glycosaminoglycan made up of two alternating monosaccharides: D-glucuronic acid (GlcA) and N-acetyl-D-galactosamine (GalNAc).") +AnnotationAssertion( "bf") +AnnotationAssertion( "2010-03-12T10:25:34Z") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0035374") +AnnotationAssertion(rdfs:label "chondroitin sulfate binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (transepithelial water transport) + +AnnotationAssertion(Annotation( "GOC:yaf") "The directed movement of water (H2O) from one side of an epithelium to the other.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2010-03-18T10:55:38Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035377") +AnnotationAssertion(rdfs:label "transepithelial water transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (carbon dioxide transmembrane transport) + +AnnotationAssertion(Annotation( "GOC:yaf") "The process in which carbon dioxide (CO2) is transported across a membrane.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2010-03-18T11:17:54Z") +AnnotationAssertion( "carbon dioxide membrane transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035378") +AnnotationAssertion(rdfs:comment "Note that this term is not intended for use in annotating lateral movement within membranes.") +AnnotationAssertion(rdfs:label "carbon dioxide transmembrane transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (carbon dioxide transmembrane transporter activity) + +AnnotationAssertion(Annotation( "GOC:yaf") "Enables the transfer of carbon dioxide (CO2) from one side of a membrane to the other.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2010-03-18T11:19:38Z") +AnnotationAssertion(Annotation(rdfs:label "AQP1 tetramer transports CO2 from extracellular region to cytosol") "Reactome:R-HSA-1237042") +AnnotationAssertion(Annotation(rdfs:label "RHAG transports CO2 from extracellular region to cytosol") "Reactome:R-HSA-1237069") +AnnotationAssertion(Annotation(rdfs:label "RHAG transports CO2 from cytosol to extracellular region") "Reactome:R-HSA-1247645") +AnnotationAssertion(Annotation(rdfs:label "AQP1 tetramer transports CO2 from cytosol to extracellular region") "Reactome:R-HSA-1247649") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0035379") +AnnotationAssertion(rdfs:label "carbon dioxide transmembrane transporter activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "GO_REF:0000090") ObjectSomeValuesFrom( )) + +# Class: (protein localization to synapse) + +AnnotationAssertion(Annotation( "GOC:bf") "Any process in which a protein is transported to, and/or maintained at the synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2010-03-29T10:58:53Z") +AnnotationAssertion(Annotation( "GOC:mah") "protein localisation to synapse") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035418") +AnnotationAssertion(rdfs:label "protein localization to synapse") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (acetate transmembrane transport) + +AnnotationAssertion(Annotation( "GOC:vw") "The process in which acetate is transported across a membrane. Acetate is the 2-carbon carboxylic acid ethanoic acid.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2010-04-08T10:59:01Z") +AnnotationAssertion( "acetate membrane transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035433") +AnnotationAssertion(rdfs:comment "Note that this term is not intended for use in annotating lateral movement within membranes.") +AnnotationAssertion(rdfs:label "acetate transmembrane transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (phosphate ion transmembrane transport) + +AnnotationAssertion(Annotation( "GOC:vw") "The process in which a phosphate is transported across a membrane.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2010-04-08T11:24:06Z") +AnnotationAssertion( "phosphate ion membrane transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035435") +AnnotationAssertion(rdfs:comment "Note that this term is not intended for use in annotating lateral movement within membranes.") +AnnotationAssertion(rdfs:label "phosphate ion transmembrane transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (cell migration involved in vasculogenesis) + +AnnotationAssertion(Annotation( "GOC:dgh") "The orderly movement of a cell from one site to another that will contribute to the differentiation of an endothelial cell that will form de novo blood vessels and tubes.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2010-04-09T03:53:01Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035441") +AnnotationAssertion(rdfs:label "cell migration involved in vasculogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (intracellular signal transduction) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:jl") Annotation( "GOC:signaling") Annotation( "ISBN:3527303782") "The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2010-05-14T01:14:37Z") +AnnotationAssertion( "GO:0007242") +AnnotationAssertion( "GO:0007243") +AnnotationAssertion( "GO:0023013") +AnnotationAssertion( "GO:0023034") +AnnotationAssertion(Annotation( "ISBN:3527303782") "intracellular signaling chain") +AnnotationAssertion(Annotation( "GOC:signaling") "intracellular protein kinase cascade") +AnnotationAssertion( "intracellular signal transduction pathway") +AnnotationAssertion(Annotation( "GOC:signaling") "protein kinase cascade") +AnnotationAssertion( "signal transmission via intracellular cascade") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:signaling") "intracellular signaling cascade") +AnnotationAssertion( "intracellular signaling pathway") +AnnotationAssertion( "signal transduction via intracellular signaling cascade") +AnnotationAssertion( "GO:0035556") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "intracellular signal transduction") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of chromatin binding) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "PMID:20404130") "Any process that modulates the frequency, rate or extent of chromatin binding. Chromatin binding is the selective interaction with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2010-05-19T10:28:36Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035561") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "regulation of chromatin binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of chromatin binding) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "PMID:20404130") "Any process that stops or reduces the frequency, rate or extent of chromatin binding. Chromatin binding is the selective interaction with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2010-05-19T10:29:06Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035562") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "negative regulation of chromatin binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of chromatin binding) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "PMID:20404130") "Any process that increases the frequency, rate or extent of chromatin binding. Chromatin binding is the selective interaction with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2010-05-19T10:29:41Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035563") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "positive regulation of chromatin binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (azurophil granule membrane) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "PMID:17152095") "The lipid bilayer surrounding an azurophil granule, a primary lysosomal granule found in neutrophil granulocytes that contains a wide range of hydrolytic enzymes and is released into the extracellular fluid.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2010-10-05T01:29:10Z") +AnnotationAssertion( "primary granule membrane") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0035577") +AnnotationAssertion(rdfs:label "azurophil granule membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (G protein-coupled purinergic receptor signaling pathway) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "PMID:9755289") "A G protein-coupled receptor signaling pathway initiated by an extracellular purine or purine derivative binding to its receptor, and ending with the regulation of a downstream cellular process.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2010-10-22T11:11:53Z") +AnnotationAssertion( "G-protein coupled purinergic receptor signaling pathway") +AnnotationAssertion(Annotation( "GOC:mah") "G-protein coupled purinergic receptor signalling pathway") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035588") +AnnotationAssertion(rdfs:label "G protein-coupled purinergic receptor signaling pathway") +SubClassOf( ) +SubClassOf( ) + +# Class: (G protein-coupled purinergic nucleotide receptor signaling pathway) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "PMID:9755289") "A G protein-coupled receptor signaling pathway initiated by an extracellular purine nucleotide binding to its receptor, and ending with the regulation of a downstream cellular process.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2010-10-22T11:18:59Z") +AnnotationAssertion( "G-protein coupled purinergic nucleotide receptor signaling pathway") +AnnotationAssertion(Annotation( "GOC:mah") "G-protein coupled purinergic nucleotide receptor signalling pathway") +AnnotationAssertion(Annotation( "PMID:9755289") "P2Y receptor signaling pathway") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035589") +AnnotationAssertion(rdfs:label "G protein-coupled purinergic nucleotide receptor signaling pathway") +SubClassOf( ) + +# Class: (purinergic nucleotide receptor signaling pathway) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "PMID:9755289") "The series of molecular signals initiated by an extracellular purine nucleotide binding to its receptor, and ending with the regulation of a downstream cellular process, e.g. transcription.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2010-10-22T11:09:40Z") +AnnotationAssertion( "GO:0035587") +AnnotationAssertion(Annotation( "GOC:mah") "purinergic nucleotide receptor signalling pathway") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "PMID:9755289") "P2 receptor signaling pathway") +AnnotationAssertion( "purinergic receptor signaling pathway") +AnnotationAssertion(Annotation( "GOC:mah") "purinergic receptor signalling pathway") +AnnotationAssertion(Annotation( "PMID:9755289") "purinoceptor signaling pathway") +AnnotationAssertion( "GO:0035590") +AnnotationAssertion(rdfs:label "purinergic nucleotide receptor signaling pathway") +SubClassOf( ) + +# Class: (establishment of protein localization to extracellular region) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:bf") "The directed movement of a protein to a specific location within the extracellular region.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2010-11-09T10:25:08Z") +AnnotationAssertion(Annotation( "GOC:mah") "establishment of protein localisation in extracellular region") +AnnotationAssertion( "establishment of protein localization in extracellular region") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035592") +AnnotationAssertion(rdfs:label "establishment of protein localization to extracellular region") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (intrahepatic bile duct development) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "PMID:20614624") "The progression of the intrahepatic bile ducts over time, from their formation to the mature structure. Intrahepatic bile ducts (bile ducts within the liver) collect bile from bile canaliculi in the liver, and connect to the extrahepatic bile ducts (bile ducts outside the liver).") +AnnotationAssertion( "bf") +AnnotationAssertion( "2010-12-08T04:10:50Z") +AnnotationAssertion(Annotation( "PMID:20614624") "IHBD development") +AnnotationAssertion(Annotation( "PMID:20614624") "intrahepatic biliary duct development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035622") +AnnotationAssertion(rdfs:label "intrahepatic bile duct development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (ceramide transport) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:sart") "The directed movement of ceramides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Ceramides are a class of lipid composed of sphingosine linked to a fatty acid.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2010-12-10T10:02:16Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035627") +AnnotationAssertion(rdfs:label "ceramide transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (cystic duct development) + +AnnotationAssertion(Annotation( "PMID:20614624") "The progression of the cystic duct over time, from its formation to the mature structure. The cystic duct runs from the gallbladder to the common bile duct.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2010-12-10T01:24:28Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035628") +AnnotationAssertion(rdfs:label "cystic duct development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (bone mineralization involved in bone maturation) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:bf") "The deposition of hydroxyapatite, involved in the progression of the skeleton from its formation to its mature state.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2010-12-20T01:57:31Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035630") +AnnotationAssertion(rdfs:comment "Bone mineralization can also occur after a fracture and as a response to stress; in these cases, consider using the term 'bone mineralization ; GO:0030282'.") +AnnotationAssertion(rdfs:label "bone mineralization involved in bone maturation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (purine ribonucleoside triphosphate binding) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:ebc") Annotation( "ISBN:0198506732") "Binding to a purine ribonucleoside triphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with triphosphate on the sugar.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-01-14T02:46:42Z") +AnnotationAssertion(Annotation( "GOC:ebc") "purine NTP binding") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0035639") +AnnotationAssertion(rdfs:label "purine ribonucleoside triphosphate binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (enteric smooth muscle cell differentiation) + +AnnotationAssertion(Annotation( "CL:0002504") Annotation( "GOC:BHF") "The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell of the intestine.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-01-21T02:58:58Z") +AnnotationAssertion(Annotation( "CL:0002504") "intestinal smooth muscle cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035645") +AnnotationAssertion(rdfs:label "enteric smooth muscle cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (neuromast hair cell development) + +AnnotationAssertion(Annotation( "CL:0000856") "The process whose specific outcome is the progression of a neuromast hair cell over time, from its formation to the mature structure. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. Cell development does not include the steps involved in committing a cell to a specific fate.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-02-14T11:01:42Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035675") +AnnotationAssertion(rdfs:label "neuromast hair cell development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (anterior lateral line neuromast hair cell development) + +AnnotationAssertion(Annotation( "ISBN:0125296509") Annotation( "ISBN:0387968377") "The process whose specific outcome is the progression of an anterior lateral line neuromast hair cell over time, from its formation to the mature structure. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. Cell development does not include the steps involved in committing a cell to a specific fate.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-02-14T11:03:57Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035676") +AnnotationAssertion(rdfs:label "anterior lateral line neuromast hair cell development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (posterior lateral line neuromast hair cell development) + +AnnotationAssertion(Annotation( "ISBN:0125296509") "The process whose specific outcome is the progression of a posterior lateral line neuromast hair cell over time, from its formation to the mature structure. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. Cell development does not include the steps involved in committing a cell to a specific fate.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-02-14T11:04:57Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035677") +AnnotationAssertion(rdfs:label "posterior lateral line neuromast hair cell development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (neuromast hair cell morphogenesis) + +AnnotationAssertion(Annotation( "CL:0000856") "The change in form (cell shape and size) that occurs when a neuromast hair cell progresses from its initial formation to its mature state. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-02-14T11:06:15Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035678") +AnnotationAssertion(rdfs:label "neuromast hair cell morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (astrocyte chemotaxis) + +AnnotationAssertion(Annotation( "CL:0000127") Annotation( "GOC:BHF") Annotation( "PMID:12271471") "The directed movement of an astrocyte guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-02-28T03:17:52Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035700") +AnnotationAssertion(rdfs:label "astrocyte chemotaxis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (hematopoietic stem cell migration) + +AnnotationAssertion(Annotation( "CL:0000037") Annotation( "GOC:BHF") Annotation( "PMID:20234092") "The orderly movement of a hematopoietic stem cell from one site to another. A hematopoietic stem cell is a cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-02-28T03:20:36Z") +AnnotationAssertion(Annotation( "CL:0000037") "hemopoietic stem cell migration") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035701") +AnnotationAssertion(rdfs:label "hematopoietic stem cell migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (monocyte homeostasis) + +AnnotationAssertion(Annotation( "CL:0000576") Annotation( "GOC:BHF") Annotation( "PMID:18832716") "The process of regulating the proliferation and elimination of monocytes such that the total number of monocytes within a whole or part of an organism is stable over time in the absence of an outside stimulus.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-03-02T11:32:57Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035702") +AnnotationAssertion(rdfs:label "monocyte homeostasis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (sodium ion transmembrane transport) + +AnnotationAssertion(Annotation( "GOC:vw") "A process in which a sodium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-03-10T02:52:36Z") +AnnotationAssertion( "sodium ion membrane transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035725") +AnnotationAssertion(rdfs:comment "Note that this term is not intended for use in annotating lateral movement within membranes.") +AnnotationAssertion(rdfs:label "sodium ion transmembrane transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (hepatic stellate cell activation) + +AnnotationAssertion(Annotation( "CL:0000632") Annotation( "GOC:bf") "A change in the morphology or behavior of a hepatic stellate cell resulting from exposure to a cytokine, chemokine, hormone, cellular ligand or soluble factor.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-03-11T10:04:12Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035733") +AnnotationAssertion(rdfs:label "hepatic stellate cell activation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + # Class: (intraciliary transport involved in cilium assembly) AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:cilia") Annotation( "Reactome:R-HSA-5620924.2") "The bidirectional movement of large protein complexes along microtubules within a cilium that contributes to cilium assembly.") @@ -35198,6 +77891,260 @@ AnnotationAssertion( "intraflagellar transport involved in cilium morphogenesis") AnnotationAssertion( "GO:0035735") AnnotationAssertion(rdfs:label "intraciliary transport involved in cilium assembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (cell proliferation involved in compound eye morphogenesis) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:sart") "The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to compound eye morphogenesis.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-03-17T10:57:03Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035736") +AnnotationAssertion(rdfs:label "cell proliferation involved in compound eye morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (B cell chemotaxis) + +AnnotationAssertion(Annotation( "CL:0000236") Annotation( "GOC:BHF") "The directed movement of a B cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-03-23T10:30:33Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035754") +AnnotationAssertion(rdfs:label "B cell chemotaxis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (dorsal motor nucleus of vagus nerve maturation) + +AnnotationAssertion(Annotation( "GOC:dgh") "A developmental process, independent of morphogenetic (shape) change, that is required for the dorsal motor nucleus of the vagus nerve to attain its fully functional state.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-03-29T02:45:50Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035761") +AnnotationAssertion(rdfs:label "dorsal motor nucleus of vagus nerve maturation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (dorsal motor nucleus of vagus nerve morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dgh") "The process in which the dorsal motor nucleus of the vagus nerve is generated and organized. Morphogenesis pertains to the creation of form.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-03-29T02:47:18Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035762") +AnnotationAssertion(rdfs:label "dorsal motor nucleus of vagus nerve morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (dorsal motor nucleus of vagus nerve formation) + +AnnotationAssertion(Annotation( "GOC:dgh") "The process that gives rise to the dorsal motor nucleus of the vagus nerve. This process pertains to the initial formation of a structure from unspecified parts.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-03-29T02:48:26Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035764") +AnnotationAssertion(rdfs:label "dorsal motor nucleus of vagus nerve formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (motor neuron precursor migration involved in dorsal motor nucleus of vagus nerve formation) + +AnnotationAssertion(Annotation( "GOC:dgh") Annotation( "PMID:21262462") "The orderly movement of a motor neuron precursor cell that contributes to formation of the dorsal motor nucleus of the vagus nerve.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-03-29T02:52:09Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035765") +AnnotationAssertion(rdfs:label "motor neuron precursor migration involved in dorsal motor nucleus of vagus nerve formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (endothelial cell chemotaxis) + +AnnotationAssertion(Annotation( "CL:0000115") Annotation( "GOC:BHF") "The directed movement of an endothelial cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-03-31T04:31:37Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035767") +AnnotationAssertion(rdfs:label "endothelial cell chemotaxis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (insulin secretion involved in cellular response to glucose stimulus) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:yaf") Annotation( "PMID:8492079") "The regulated release of proinsulin from secretory granules (B granules) in the B cells of the pancreas; accompanied by cleavage of proinsulin to form mature insulin, in response to a glucose stimulus.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-04-01T01:14:40Z") +AnnotationAssertion(Annotation( "GOC:bf") "insulin secretion involved in cellular response to glucose") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035773") +AnnotationAssertion(rdfs:label "insulin secretion involved in cellular response to glucose stimulus") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of insulin secretion involved in cellular response to glucose stimulus) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:yaf") "Any process that increases the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-04-01T01:49:09Z") +AnnotationAssertion(Annotation( "GOC:bf") "positive regulation of insulin secretion in response to glucose") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035774") +AnnotationAssertion(rdfs:label "positive regulation of insulin secretion involved in cellular response to glucose stimulus") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (pronephric glomerulus morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") Annotation( "GOC:yaf") Annotation( "PMID:18787069") "The process in which the anatomical structures of the pronephric glomerulus are generated and organized. The pronephric glomerulus is part of the pronephric nephron and is restricted to one body segment.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-04-04T10:59:28Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035775") +AnnotationAssertion(rdfs:comment "This term is intended for annotation of fish and other organisms which contain a glomerulus as part of the pronephric nephron. It should not be used for annotation of Xenopus, which contains a pronephric glomus rather than a glomerulus.") +AnnotationAssertion(rdfs:label "pronephric glomerulus morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (pronephric proximal tubule development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") Annotation( "GOC:yaf") Annotation( "PMID:18787069") "The progression of the pronephric proximal tubule over time, from its formation to the mature structure. A pronephric nephron tubule is an epithelial tube that is part of the pronephros.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-04-04T11:02:54Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035776") +AnnotationAssertion(rdfs:label "pronephric proximal tubule development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (pronephric distal tubule development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") Annotation( "GOC:yaf") Annotation( "PMID:18787069") "The process whose specific outcome is the progression of the pronephric distal tubule over time, from its formation to the mature structure. A pronephric nephron tubule is an epithelial tube that is part of the pronephros.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-04-04T11:06:01Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035777") +AnnotationAssertion(rdfs:label "pronephric distal tubule development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (pronephric nephron tubule epithelial cell differentiation) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") Annotation( "GOC:yaf") Annotation( "PMID:18787069") "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the pronephric nephron tubule as it progresses from its formation to the mature state.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-04-04T11:07:47Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035778") +AnnotationAssertion(rdfs:label "pronephric nephron tubule epithelial cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (angioblast cell differentiation) + +AnnotationAssertion(Annotation( "CL:0000566") Annotation( "GOC:yaf") "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an angioblast cell. Angioblasts are one of the two products formed from hemangioblast cells (the other being pluripotent hemopoietic stem cells).") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-04-04T11:10:38Z") +AnnotationAssertion(Annotation( "CL:0000566") "angioblastic mesenchymal cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035779") +AnnotationAssertion(rdfs:label "angioblast cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cell migration involved in kidney development) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:mtg_kidney_jan10") Annotation( "GOC:yaf") "The orderly movement of a cell from one site to another that will contribute to the progression of the kidney over time, from its formation to the mature organ.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-04-06T10:39:52Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035787") +AnnotationAssertion(rdfs:label "cell migration involved in kidney development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (cell migration involved in metanephros development) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:mtg_kidney_jan10") Annotation( "GOC:yaf") "The orderly movement of a cell from one site to another that will contribute to the progression of the metanephric kidney over time, from its formation to the mature organ.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-04-06T10:42:21Z") +AnnotationAssertion(Annotation( "GOC:bf") "cell migration involved in metanephric kidney development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035788") +AnnotationAssertion(rdfs:label "cell migration involved in metanephros development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (ureter maturation) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:mtg_kidney_jan10") Annotation( "GOC:yaf") Annotation( "PMID:17881463") "A developmental process, independent of morphogenetic (shape) change, that is required for the ureter to attain its fully functional state. The ureter is a muscular tube that transports urine from the kidney to the urinary bladder or from the Malpighian tubule to the hindgut.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-04-14T01:13:39Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035799") +AnnotationAssertion(rdfs:label "ureter maturation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (adrenal cortex development) + +AnnotationAssertion(Annotation( "PMID:12185666") Annotation( "PMID:21115154") Annotation( "Wikipedia:Adrenal_cortex") "The process whose specific outcome is the progression of the adrenal cortex over time, from its formation to the mature structure. The adrenal cortex is located at the periphery of the adrenal gland and controls glucose and electrolyte metabolism, response to stress and sexual development through the production of different classes of steroid hormones (glucocorticoids, mineralocorticoids and androgens).") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-04-18T10:25:39Z") +AnnotationAssertion(Annotation( "MA:0000118") "adrenal gland cortex development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035801") +AnnotationAssertion(rdfs:label "adrenal cortex development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (adrenal cortex formation) + +AnnotationAssertion(Annotation( "PMID:12185666") Annotation( "PMID:21115154") "The process that gives rise to the adrenal cortex. This process pertains to the initial formation of a structure from unspecified parts. The adrenogonadal primordium from which the adrenal cortex is formed derives from a condensation of coelomic epithelial cells (the urogenital ridge; the same structure from which gonads and kidney also originate).") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-04-18T10:26:49Z") +AnnotationAssertion(Annotation( "MA:0000118") "adrenal gland cortex formation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035802") +AnnotationAssertion(rdfs:label "adrenal cortex formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (egg coat formation) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:sart") Annotation( "GOC:yaf") Annotation( "PMID:16944418") Annotation( "PMID:17163408") "Construction of an egg coat, a specialized extracellular matrix that surrounds the ovum of animals. The egg coat provides structural support and can play an essential role in oogenesis, fertilization and early development.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-04-19T01:48:43Z") +AnnotationAssertion(Annotation( "PMID:16944418") Annotation( "PMID:17163408") "VE formation") +AnnotationAssertion(Annotation( "PMID:18420282") "ZP assembly") +AnnotationAssertion(Annotation( "PMID:16944418") "vitelline envelope formation") +AnnotationAssertion(Annotation( "GOC:yaf") Annotation( "PMID:18420282") "zona pellucida assembly") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035803") +AnnotationAssertion(rdfs:label "egg coat formation") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (egg coat) + +AnnotationAssertion(Annotation( "PMID:16944418") Annotation( "PMID:17163408") "A specialized extracellular matrix that surrounds the plasma membrane of the ovum of animals. The egg coat provides structural support and can play an essential role in oogenesis, fertilization and early development.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-04-19T02:07:23Z") +AnnotationAssertion(Annotation( "PMID:16944418") Annotation( "PMID:17163408") "vitelline membrane") +AnnotationAssertion(Annotation( "PMID:16944418") Annotation( "PMID:17163408") "zona pellucida") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0035805") +AnnotationAssertion(rdfs:label "egg coat") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectAllValuesFrom( )) # Class: (regulation of urine volume) @@ -35212,6 +78159,202 @@ AnnotationAssertion(rdfs:label "regu SubClassOf( ) SubClassOf( ) +# Class: (indole alkaloid metabolic process) + +AnnotationAssertion(Annotation( "GOC:yaf") "The chemical reactions and pathways involving an indole alkaloid, an alkaloid containing an indole skeleton.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-05-04T03:17:44Z") +AnnotationAssertion(Annotation( "GOC:bf") "indole alkaloid metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035834") +AnnotationAssertion(rdfs:label "indole alkaloid metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (indole alkaloid biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:yaf") "The chemical reactions and pathways resulting in the formation of an indole alkaloid, an alkaloid containing an indole skeleton.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-05-04T03:18:31Z") +AnnotationAssertion(Annotation( "GOC:bf") "indole alkaloid anabolism") +AnnotationAssertion(Annotation( "GOC:bf") "indole alkaloid biosynthesis") +AnnotationAssertion(Annotation( "GOC:bf") "indole alkaloid formation") +AnnotationAssertion(Annotation( "GOC:bf") "indole alkaloid synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035835") +AnnotationAssertion(rdfs:label "indole alkaloid biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (cloaca development) + +AnnotationAssertion(Annotation( "GOC:dgh") Annotation( "ISBN:0582227089") "The process whose specific outcome is the progression of the cloaca over time, from it's formation to the mature structure. The cloaca is the common chamber into which intestinal, genital and urinary canals open in vertebrates.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-05-06T01:54:35Z") +AnnotationAssertion(Annotation( "GOC:bf") "cloacal development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035844") +AnnotationAssertion(rdfs:label "cloaca development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (photoreceptor cell outer segment organization) + +AnnotationAssertion(Annotation( "ISBN:0824072820") Annotation( "PMID:14507858") "A process that is carried out at the cellular level and results in the assembly, arrangement of constituent parts, or disassembly of the outer segment of a photoreceptor cell, a sensory cell that reacts to the presence of light. The outer segment of the photoreceptor cell contains the light-absorbing materials.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-05-10T10:44:09Z") +AnnotationAssertion(Annotation( "GOC:mah") "photoreceptor cell outer segment organisation") +AnnotationAssertion(Annotation( "GOC:bf") "photoreceptor outer segment organization") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035845") +AnnotationAssertion(rdfs:label "photoreceptor cell outer segment organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (oviduct epithelium development) + +AnnotationAssertion(Annotation( "GOC:yaf") Annotation( "http://www.thefreedictionary.com/oviduct") "The progression of the oviduct epithelium over time from its initial formation to the mature structure. An oviduct is a tube through which an ova passes from the ovary to the uterus, or from the ovary to the outside of the organism. The oviduct epithelium is the specialized epithelium that lines the oviduct.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-05-10T10:53:05Z") +AnnotationAssertion(Annotation( "GOC:yaf") "fallopian tube epithelium development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035846") +AnnotationAssertion(rdfs:label "oviduct epithelium development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (uterine epithelium development) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:yaf") "The progression of an epithelium of the uterus over time from its initial formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-05-10T10:57:45Z") +AnnotationAssertion(Annotation( "GOC:yaf") "uterus epithelial development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035847") +AnnotationAssertion(rdfs:label "uterine epithelium development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (oviduct morphogenesis) + +AnnotationAssertion(Annotation( "GOC:yaf") Annotation( "http://www.thefreedictionary.com/oviduct") "The process in which anatomical structures of the oviduct are generated and organized. An oviduct is a tube through which an ova passes from the ovary to the uterus, or from the ovary to the outside of the organism.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-05-10T11:01:20Z") +AnnotationAssertion(Annotation( "GOC:yaf") "fallopian tube morphogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035848") +AnnotationAssertion(rdfs:label "oviduct morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (epithelial cell differentiation involved in kidney development) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:mtg_kidney_jan10") Annotation( "GOC:yaf") Annotation( "PMID:16216236") "The process in which relatively unspecialized cells acquire specialized structural and/or functional features of an epithelial cell that characterize the cells of the kidney as it progresses from its formation to the mature state.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-05-11T11:34:21Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035850") +AnnotationAssertion(rdfs:label "epithelial cell differentiation involved in kidney development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (megakaryocyte development) + +AnnotationAssertion(Annotation( "CL:0000556") Annotation( "GOC:BHF") Annotation( "GOC:vk") "The process whose specific outcome is the progression of a megakaryocyte cell over time, from its formation to the mature structure. Megakaryocyte development does not include the steps involved in committing a cell to a megakaryocyte fate. A megakaryocyte is a giant cell 50 to 100 micron in diameter, with a greatly lobulated nucleus, found in the bone marrow.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-05-13T01:28:06Z") +AnnotationAssertion(Annotation( "GOC:bf") "megakaryocyte cell development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035855") +AnnotationAssertion(rdfs:label "megakaryocyte development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (ciliary transition zone) + +AnnotationAssertion(Annotation( "GOC:cilia") Annotation( "GOC:kmv") Annotation( "PMID:21422230") "A region of the cilium between the basal body and proximal segment that is characterized by Y-shaped assemblages that connect axonemal microtubules to the ciliary membrane. The ciliary transition zone appears to function as a gate that controls ciliary membrane composition and separates the cytosol from the ciliary plasm.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-05-25T03:09:58Z") +AnnotationAssertion( "cilial transition zone") +AnnotationAssertion( "cilium transition zone") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "connecting cilium") +AnnotationAssertion( "GO:0035869") +AnnotationAssertion(rdfs:comment "Depending on the species, this region may have a distinct geometrically shaped electron-dense structure within the axonemal lumen visible in electron microscopy images; most animals don't display this inner structure. The axoneme extends through the ciliary transition zone, but only consists of the outer doublets. The central pair, axonemal spokes, and dynein complexes are not found in this part of the ciliary shaft. Note that the connecting cilium of the photoreceptor cells is thought to be equivalent to the transition zone.") +AnnotationAssertion(rdfs:label "ciliary transition zone") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (nail development) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "ISBN:0323025781") Annotation( "UBERON:0001705") Annotation( "Wikipedia:Nail_(anatomy)") "The process whose specific outcome is the progression of a nail over time, from its formation to the mature structure. A nail is a horn-like envelope covering the outer end of a finger or toe, and consists of the nail plate, the nail matrix and the nail bed below it, and the grooves surrounding it.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-05-31T02:30:34Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035878") +AnnotationAssertion(rdfs:label "nail development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (amacrine cell differentiation) + +AnnotationAssertion(Annotation( "CL:0000561") Annotation( "GOC:bf") "The process in which a relatively unspecialized cell acquires specialized features of an amacrine cell, an interneuron generated in the inner nuclear layer (INL) of the vertebrate retina. Amacrine cells integrate, modulate, and interpose a temporal domain in the visual message presented to the retinal ganglion cells, with which they synapse in the inner plexiform layer. Amacrine cells lack large axons.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-06-06T11:32:50Z") +AnnotationAssertion(Annotation( "CL:0000561") "amacrine neuron differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035881") +AnnotationAssertion(rdfs:label "amacrine cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (enteroendocrine cell differentiation) + +AnnotationAssertion(Annotation( "CL:0000164") Annotation( "GOC:bf") "The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of an enteroendocrine cell. Enteroendocrine cells are hormonally active epithelial cells in the gut that constitute the diffuse neuroendocrine system.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-06-06T11:48:51Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035883") +AnnotationAssertion(rdfs:label "enteroendocrine cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (vascular associated smooth muscle cell differentiation) + +AnnotationAssertion(Annotation( "GOC:sl") Annotation( "PMID:16151017") Annotation( "PMID:18267954") "The process in which a relatively unspecialized cell acquires specialized features of a vascular smooth muscle cell.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-06-08T11:23:52Z") +AnnotationAssertion(Annotation( "PMID:16151017") "VSMC differentiation") +AnnotationAssertion( "vascular smooth muscle cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035886") +AnnotationAssertion(rdfs:label "vascular associated smooth muscle cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (aortic smooth muscle cell differentiation) + +AnnotationAssertion(Annotation( "GOC:sl") "The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell surrounding the aorta.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-06-08T11:34:26Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035887") +AnnotationAssertion(rdfs:label "aortic smooth muscle cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + # Class: (parathyroid hormone secretion) AnnotationAssertion(Annotation( "GOC:cjm") Annotation( "PMID:12171519") Annotation( "PMID:21164021") "The regulated release of parathyroid hormone into the circulatory system.") @@ -35225,6 +78368,141 @@ AnnotationAssertion( "parathyroid hormone secretion") SubClassOf( ) +# Class: (aorta development) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:dgh") Annotation( "MA:0000062") Annotation( "UBERON:0000947") Annotation( "Wikipedia:Aorta") "The progression of the aorta over time, from its initial formation to the mature structure. An aorta is an artery that carries blood from the heart to other parts of the body.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-06-24T11:00:07Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035904") +AnnotationAssertion(rdfs:label "aorta development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (ascending aorta development) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:dgh") Annotation( "MA:0002570") Annotation( "UBERON:0001496") Annotation( "Wikipedia:Ascending_aorta") "The progression of the ascending aorta over time, from its initial formation to the mature structure. The ascending aorta is the portion of the aorta in a two-pass circulatory system that lies between the heart and the arch of aorta. In a two-pass circulatory system blood passes twice through the heart to supply the body once.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-06-24T11:02:01Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035905") +AnnotationAssertion(rdfs:label "ascending aorta development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (descending aorta development) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:dgh") Annotation( "MA:0002571") Annotation( "UBERON:0001514") Annotation( "Wikipedia:Descending_aorta") "The progression of the descending aorta over time, from its initial formation to the mature structure. The descending aorta is the portion of the aorta in a two-pass circulatory system from the arch of aorta to the point where it divides into the common iliac arteries. In a two-pass circulatory system blood passes twice through the heart to supply the body once.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-06-24T11:05:22Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035906") +AnnotationAssertion(rdfs:label "descending aorta development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (dorsal aorta development) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:dgh") Annotation( "UBERON:0005805") Annotation( "Wikipedia:Aorta") Annotation( "ZFA:0000014") "The progression of the dorsal aorta over time, from its initial formation to the mature structure. The dorsal aorta is a blood vessel in a single-pass circulatory system that carries oxygenated blood from the gills to the rest of the body. In a single-pass circulatory system blood passes once through the heart to supply the body once.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-06-24T11:07:01Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035907") +AnnotationAssertion(rdfs:label "dorsal aorta development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (ventral aorta development) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:dgh") Annotation( "UBERON:0003085") Annotation( "Wikipedia:Aorta") Annotation( "ZFA:0000604") "The progression of the ventral aorta over time, from its initial formation to the mature structure. The ventral aorta is a blood vessel in a single-pass circulatory system that carries de-oxygenated blood from the heart to the gills. In a single-pass circulatory system blood passes once through the heart to supply the body once.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-06-24T11:08:49Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035908") +AnnotationAssertion(rdfs:label "ventral aorta development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (aorta morphogenesis) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:dgh") Annotation( "MA:0000062") Annotation( "UBERON:0000947") Annotation( "Wikipedia:Aorta") "The process in which the anatomical structures of an aorta are generated and organized. An aorta is an artery that carries blood from the heart to other parts of the body.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-06-24T11:11:11Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035909") +AnnotationAssertion(rdfs:label "aorta morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (ascending aorta morphogenesis) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:dgh") Annotation( "MA:0002570") Annotation( "UBERON:0001496") Annotation( "Wikipedia:Ascending_aorta") "The process in which the anatomical structures of the ascending aorta are generated and organized. The ascending aorta is the portion of the aorta in a two-pass circulatory system that lies between the heart and the arch of aorta. In a two-pass circulatory system blood passes twice through the heart to supply the body once.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-06-24T11:14:52Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035910") +AnnotationAssertion(rdfs:label "ascending aorta morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (descending aorta morphogenesis) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:dgh") Annotation( "MA:0002571") Annotation( "UBERON:0001514") Annotation( "Wikipedia:Descending_aorta") "The process in which the anatomical structures of the descending aorta are generated and organized. The descending aorta is the portion of the aorta in a two-pass circulatory system from the arch of aorta to the point where it divides into the common iliac arteries. In a two-pass circulatory system blood passes twice through the heart to supply the body once.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-06-24T11:19:24Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035911") +AnnotationAssertion(rdfs:label "descending aorta morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (dorsal aorta morphogenesis) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:dgh") Annotation( "UBERON:0005805") Annotation( "Wikipedia:Aorta") Annotation( "ZFA:0000014") "The process in which the anatomical structures of the dorsal aorta are generated and organized. The dorsal aorta is a blood vessel in a single-pass circulatory system that carries oxygenated blood from the gills to the rest of the body. In a single-pass circulatory system blood passes once through the heart to supply the body once.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-06-24T11:22:14Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035912") +AnnotationAssertion(rdfs:label "dorsal aorta morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (ventral aorta morphogenesis) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:dgh") Annotation( "UBERON:0003085") Annotation( "Wikipedia:Aorta") Annotation( "ZFA:0000604") "The process in which the anatomical structures of the ventral aorta are generated and organized. The ventral aorta is a blood vessel in a single-pass circulatory system that carries de-oxygenated blood from the heart to the gills. In a single-pass circulatory system blood passes once through the heart to supply the body once.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-06-24T11:24:36Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035913") +AnnotationAssertion(rdfs:label "ventral aorta morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (skeletal muscle cell differentiation) + +AnnotationAssertion(Annotation( "CL:0000188") Annotation( "GOC:BHF") Annotation( "GOC:vk") "The process in which a relatively unspecialized cell acquires specialized features of a skeletal muscle cell, a somatic cell located in skeletal muscle.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-06-24T02:36:19Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035914") +AnnotationAssertion(rdfs:label "skeletal muscle cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (steroid hormone secretion) AnnotationAssertion(Annotation( "GOC:sl") "The regulated release of any steroid that acts as a hormone into the circulatory system.") @@ -35233,6 +78511,7 @@ AnnotationAssertion( AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0035929") AnnotationAssertion(rdfs:label "steroid hormone secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) @@ -35245,6 +78524,7 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:0035930") AnnotationAssertion(rdfs:label "corticosteroid hormone secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) # Class: (mineralocorticoid secretion) @@ -35255,6 +78535,7 @@ AnnotationAssertion( AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0035931") AnnotationAssertion(rdfs:label "mineralocorticoid secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) # Class: (aldosterone secretion) @@ -35265,9 +78546,146 @@ AnnotationAssertion( AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0035932") AnnotationAssertion(rdfs:label "aldosterone secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) +# Class: (glucocorticoid secretion) + +AnnotationAssertion(Annotation( "GOC:sl") "The regulated release of any glucocorticoid hormone into the circulatory system. Glucocorticoids are a class of steroid hormones that regulate a variety of physiological processes, in particular control of the concentration of glucose in blood.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-07-20T01:08:37Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035933") +AnnotationAssertion(rdfs:label "glucocorticoid secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (androgen secretion) + +AnnotationAssertion(Annotation( "GOC:sl") "The regulated release of an androgen into the circulatory system. Androgens are steroid hormones that stimulate or control the development and maintenance of masculine characteristics in vertebrates.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-07-20T01:11:31Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035935") +AnnotationAssertion(rdfs:label "androgen secretion") +SubClassOf( ) + +# Class: (testosterone secretion) + +AnnotationAssertion(Annotation( "GOC:sl") Annotation( "PMID:12606499") "The regulated release of testosterone into the circulatory system. Testosterone is an androgen having 17beta-hydroxy and 3-oxo groups, together with unsaturation at C-4-C-5.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-07-20T01:13:13Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035936") +AnnotationAssertion(rdfs:label "testosterone secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (tongue muscle cell differentiation) + +AnnotationAssertion(Annotation( "CL:0002673") Annotation( "GOC:yaf") Annotation( "PMID:3393851") "The process in which a relatively unspecialized cell acquires specialized features of a tongue muscle cell.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-08-22T01:35:16Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035981") +AnnotationAssertion(rdfs:label "tongue muscle cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (endodermal cell differentiation) + +AnnotationAssertion(Annotation( "CL:0000223") Annotation( "GOC:yaf") Annotation( "PMID:17624332") "The process in which a relatively unspecialized cell acquires the specialized features of an endoderm cell, a cell of the inner of the three germ layers of the embryo.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-08-25T04:50:36Z") +AnnotationAssertion(Annotation( "CL:0000223") "endoderm cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035987") +AnnotationAssertion(rdfs:label "endodermal cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (tendon development) + +AnnotationAssertion(Annotation( "GOC:yaf") Annotation( "PMID:21412429") Annotation( "UBERON:0000043") "The process whose specific outcome is the progression of a tendon over time, from its formation to the mature structure. A tendon is a fibrous, strong, connective tissue that connects muscle to bone or integument and is capable of withstanding tension. Tendons and muscles work together to exert a pulling force.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-08-26T04:14:30Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "UBERON:0000043") "sinew development") +AnnotationAssertion( "GO:0035989") +AnnotationAssertion(rdfs:label "tendon development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (tendon cell differentiation) + +AnnotationAssertion(Annotation( "CL:0000388") Annotation( "GOC:yaf") Annotation( "PMID:21412429") "The process in which a relatively unspecialized cell acquires the specialized features of a tendon cell. Tendon cell are elongated fibrocytes in which the cytoplasm is stretched between the collagen fibres of the tendon. Tendon cells have a central cell nucleus with a prominent nucleolus, a well-developed rough endoplasmic reticulum, and are responsible for synthesis and turnover of tendon fibres and ground substance.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-08-26T04:16:06Z") +AnnotationAssertion(Annotation( "CL:0000388") "muscle attachment cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "CL:0000388") "tenocyte differentiation") +AnnotationAssertion( "GO:0035990") +AnnotationAssertion(rdfs:label "tendon cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (tendon formation) + +AnnotationAssertion(Annotation( "GOC:yaf") Annotation( "PMID:17567668") Annotation( "UBERON:0000043") "The process that gives rise to a tendon. This process pertains to the initial formation of a tendon from unspecified parts.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-08-30T01:35:10Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035992") +AnnotationAssertion(rdfs:label "tendon formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (deltoid tuberosity development) + +AnnotationAssertion(Annotation( "GOC:yaf") Annotation( "PMID:17567668") Annotation( "UBERON:0002498") Annotation( "Wikipedia:Deltoid_tuberosity") "The process whose specific outcome is the progression of the deltoid tuberosity over time, from its formation to the mature structure. The deltoid tuberosity is the region on the shaft of the humerus to which the deltoid muscle attaches. The deltoid tuberosity develops through endochondral ossification in a two-phase process; an initiating tendon-dependent phase, and a muscle-dependent growth phase.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-08-30T01:46:53Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0035993") +AnnotationAssertion(rdfs:label "deltoid tuberosity development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (limb joint morphogenesis) + +AnnotationAssertion(Annotation( "GOC:bf") "The process in which the anatomical structures of a limb joint are generated and organized. A limb joint is a flexible region that separates the rigid sections of a limb to allow movement in a controlled manner.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-10-13T04:52:59Z") +AnnotationAssertion(Annotation( "GOC:bf") "knee morphogenesis") +AnnotationAssertion(Annotation( "GOC:bf") "leg joint morphogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0036022") +AnnotationAssertion(rdfs:label "limb joint morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (osteoclast development) + +AnnotationAssertion(Annotation( "CL:0000092") Annotation( "GOC:bf") Annotation( "GOC:yaf") "The process whose specific outcome is the progression of a osteoclast from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-11-02T05:20:35Z") +AnnotationAssertion(Annotation( "GOC:bf") "osteoclast cell development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0036035") +AnnotationAssertion(rdfs:label "osteoclast development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (direct ossification) AnnotationAssertion(Annotation( "GO_REF:0000034") "The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance, that does not require the replacement of preexisting tissues.") @@ -35299,6 +78717,65 @@ AnnotationAssertion( "replacement ossification") SubClassOf( ) +# Class: (germ cell proliferation) + +AnnotationAssertion(Annotation( "CL:0000586") Annotation( "GOC:kmv") "The multiplication or reproduction of germ cells, reproductive cells in multicellular organisms, resulting in the expansion of a cell population.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2012-01-17T04:06:27Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0036093") +AnnotationAssertion(rdfs:label "germ cell proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (small molecule binding) + +AnnotationAssertion(Annotation( "GOC:curators") Annotation( "GOC:pde") Annotation( "GOC:pm") "Binding to a small molecule, any low molecular weight, monomeric, non-encoded molecule.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2012-01-17T04:20:34Z") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0036094") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:comment "Small molecules in GO include monosaccharides but exclude disaccharides and polysaccharides.") +AnnotationAssertion(rdfs:label "small molecule binding") +SubClassOf( ) + +# Class: (female germ-line stem cell population maintenance) + +AnnotationAssertion(Annotation( "GOC:sart") "The process by which an organism or tissue maintains a population of female germ-line stem cells.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2012-01-26T01:58:10Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0036099") +AnnotationAssertion(rdfs:label "female germ-line stem cell population maintenance") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (Schwann cell migration) + +AnnotationAssertion(Annotation( "CL:0002573") Annotation( "PMID:20335460") "The orderly movement of a Schwann cell from one site to another. A Schwann cell is a glial cell that ensheathes axons of neuron in the peripheral nervous system and is necessary for their maintainance and function.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2012-03-06T10:44:39Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0036135") +AnnotationAssertion(rdfs:label "Schwann cell migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (dendritic cell homeostasis) + +AnnotationAssertion(Annotation( "CL:0000451") Annotation( "GOC:uh") Annotation( "PMID:12570827") Annotation( "PMID:19176316") "The process of regulating the proliferation and elimination of dendritic cells such that the total number of dendritic cells within a whole or part of an organism is stable over time in the absence of an outside stimulus.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2012-03-12T11:05:36Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "PMID:19176316") "DC homeostasis") +AnnotationAssertion( "GO:0036145") +AnnotationAssertion(rdfs:label "dendritic cell homeostasis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + # Class: (rumination) AnnotationAssertion(Annotation( "GOC:maf") Annotation( "Wikipedia:Rumination") "A digestive process in which food, usually grass or hay, is swallowed into a multi-compartmented stomach, regurgitated, chewed again, and swallowed again.") @@ -35310,6 +78787,17 @@ AnnotationAssertion( "rumination") SubClassOf( ) +# Class: (melanocyte-stimulating hormone secretion) + +AnnotationAssertion(Annotation( "GOC:cjm") Annotation( "Wikipedia:Melanocyte-stimulating_hormone") "The regulated release of a melanocyte-stimulating hormone, any of a group of peptide hormones that are produced by cells in the intermediate lobe of the pituitary gland, and stimulate the production of melanin to increase pigmentation.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2012-03-26T01:16:55Z") +AnnotationAssertion(Annotation( "GOC:cjm") "MSH secretion") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0036160") +AnnotationAssertion(rdfs:label "melanocyte-stimulating hormone secretion") +SubClassOf( ) + # Class: (calcitonin secretion) AnnotationAssertion(Annotation( "GOC:cjm") "The regulated release of calcitonin, a peptide hormone that participates in calcium and phosphorus metabolism, from a cell.") @@ -35318,8 +78806,22 @@ AnnotationAssertion( AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0036161") AnnotationAssertion(rdfs:label "calcitonin secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (osteoclast maturation) + +AnnotationAssertion(Annotation( "CL:0000092") Annotation( "GOC:pg") "A developmental process, independent of morphogenetic (shape) change, that is required for an osteoclast cell to attain its fully functional state. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue, and which typically differentiates from monocytes.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2012-03-29T02:04:00Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "CL:0000092") "chondroclast maturation") +AnnotationAssertion( "GO:0036179") +AnnotationAssertion(rdfs:label "osteoclast maturation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (muscle cell projection) AnnotationAssertion(Annotation( "CL:0000187") Annotation( "GOC:kmv") Annotation( "PMID:15930100") Annotation( "PMID:22464329") "A prolongation or process extending from a muscle cell. A muscle cell is a mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns.") @@ -35331,6 +78833,50 @@ AnnotationAssertion(Annotation( "cellular_component") AnnotationAssertion( "GO:0036194") AnnotationAssertion(rdfs:label "muscle cell projection") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (muscle cell projection membrane) + +AnnotationAssertion(Annotation( "CL:0000187") Annotation( "GOC:kmv") Annotation( "PMID:15930100") Annotation( "PMID:22464329") "The portion of the plasma membrane surrounding a muscle cell projection.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2012-04-20T10:21:51Z") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0036195") +AnnotationAssertion(rdfs:label "muscle cell projection membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (protein modification process) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:jl") "The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications). Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification).") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/23112"^^xsd:anyURI) +AnnotationAssertion( "bf") +AnnotationAssertion( "2012-04-26T01:47:12Z") +AnnotationAssertion( "GO:0006464") +AnnotationAssertion( "cellular protein modification process") +AnnotationAssertion( "process resulting in protein modification") +AnnotationAssertion(Annotation( "GOC:bf") "protein modification") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0036211") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "protein modification process") +SubClassOf( ) +SubClassOf( ) + +# Class: (granulocyte activation) + +AnnotationAssertion(Annotation( "CL:0000094") Annotation( "GOC:nhn") "The change in morphology and behavior of a granulocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2012-05-11T10:57:48Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0036230") +AnnotationAssertion(rdfs:label "granulocyte activation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) # Class: (response to decreased oxygen levels) @@ -35344,6 +78890,138 @@ AnnotationAssertion(rdfs:comment "Th AnnotationAssertion(rdfs:label "response to decreased oxygen levels") SubClassOf( ) +# Class: (atrioventricular canal development) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:gr") Annotation( "PMID:14701881") Annotation( "UBERON:0002087") Annotation( "ZFA:0001315") "The progression of the atrioventricular canal over time, from its formation to the mature structure. The atrioventricular canal is the part of the heart connecting the atrium to the cardiac ventricle.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2012-08-08T09:55:37Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0036302") +AnnotationAssertion(rdfs:label "atrioventricular canal development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (lymph vessel morphogenesis) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:gr") Annotation( "PMID:18093989") "The process in which the anatomical structures of lymph vessels are generated and organized. The lymph vessel is the vasculature carrying lymph.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2012-08-08T10:08:47Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0036303") +AnnotationAssertion(rdfs:label "lymph vessel morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (umbilical cord morphogenesis) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:gr") Annotation( "PMID:15107403") "The process in which the anatomical structures of the umbilical cord are generated and organized. The umbilical cord is an organ or embryonic origin consisting of the 2 umbilical arteries and the one umbilical vein. The umbilical cord connects the cardiovascular system of the fetus to the mother via the placenta.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2012-08-08T10:12:11Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0036304") +AnnotationAssertion(rdfs:label "umbilical cord morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (ameloblast differentiation) + +AnnotationAssertion(Annotation( "CL:0000059") "The process in which a relatively unspecialized cell acquires specialized features of an ameloblast, a cylindrical epithelial cell in the innermost layer of the enamel organ.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2012-08-08T13:49:15Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0036305") +AnnotationAssertion(rdfs:label "ameloblast differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (hepatocyte homeostasis) + +AnnotationAssertion(Annotation( "CL:0000182") Annotation( "GOC:nhn") Annotation( "PMID:19878874") "Any biological process involved in the maintenance of the steady-state number of hepatocytes within a population of cells. Hepatocytes are specialized epithelial cells of the liver that are organized into interconnected plates called lobules.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2012-09-05T10:17:07Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0036333") +AnnotationAssertion(rdfs:label "hepatocyte homeostasis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (epidermal stem cell homeostasis) + +AnnotationAssertion(Annotation( "CL:1000428") Annotation( "GOC:nhn") Annotation( "PMID:17666529") "Any biological process involved in the maintenance of the steady-state number of epidermal stem cells within a population of cells.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2012-09-05T10:21:23Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0036334") +AnnotationAssertion(rdfs:label "epidermal stem cell homeostasis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (dendritic cell migration) + +AnnotationAssertion(Annotation( "CL:0000451") Annotation( "GOC:nhn") Annotation( "PMID:19339990") "The movement of a dendritic cell within or between different tissues and organs of the body.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2012-09-05T10:24:46Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0036336") +AnnotationAssertion(rdfs:label "dendritic cell migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (post-anal tail morphogenesis) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:kmv") Annotation( "Wikipedia:Chordate") "The process in which a post-anal tail is generated and organized. A post-anal tail is a muscular region of the body that extends posterior to the anus. The post-anal tail may aid locomotion and balance.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2012-09-11T13:54:49Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0036342") +AnnotationAssertion(rdfs:label "post-anal tail morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectAllValuesFrom( )) + +# Class: (platelet morphogenesis) + +AnnotationAssertion(Annotation( "CL:0000233") Annotation( "GOC:BHF") Annotation( "GOC:vk") "Generation and organization of a platelet, a non-nucleated disk-shaped cell formed by extrusion from megakaryocytes, found in the blood of all mammals, and mainly involved in blood coagulation.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2012-09-11T15:15:35Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0036344") +AnnotationAssertion(rdfs:label "platelet morphogenesis") +SubClassOf( ) + +# Class: (platelet maturation) + +AnnotationAssertion(Annotation( "CL:0000233") Annotation( "GOC:BHF") Annotation( "GOC:vk") "A developmental process, independent of morphogenetic (shape) change, that is required for a platelet to attain its fully functional state. A platelet is a non-nucleated disk-shaped cell formed by extrusion from megakaryocytes, found in the blood of all mammals, and mainly involved in blood coagulation.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2012-09-11T15:23:11Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0036345") +AnnotationAssertion(rdfs:label "platelet maturation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (sodium ion export across plasma membrane) + +AnnotationAssertion(Annotation( "GOC:vw") Annotation( "PMID:14674689") "The directed movement of sodium ions from inside of a cell, across the plasma membrane and into the extracellular region.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2009-12-16T11:13:55Z") +AnnotationAssertion( "GO:0071436") +AnnotationAssertion( "GO:0098667") +AnnotationAssertion( "sodium ion export from cell") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:mah") "sodium export") +AnnotationAssertion( "sodium ion export") +AnnotationAssertion( "GO:0036376") +AnnotationAssertion(rdfs:label "sodium ion export across plasma membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + # Class: (myofilament) AnnotationAssertion(Annotation( "Wikipedia:Myofilament") "Any of the smallest contractile units of a myofibril (striated muscle fiber).") @@ -35368,6 +79046,372 @@ AnnotationAssertion(rdfs:label "soma SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (trunk neural crest cell migration) + +AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:bf") Annotation( "GOC:mat") Annotation( "PMID:2387238") "The characteristic movement of trunk neural crest cells from the neural tube to other locations in the vertebrate embryo.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2014-08-26T15:27:44Z") +AnnotationAssertion(Annotation( "PMID:2387238") "trunk NCC migration") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0036484") +AnnotationAssertion(rdfs:label "trunk neural crest cell migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (Golgi membrane fusion) + +AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:bf") Annotation( "PMID:12473691") "The joining of two lipid bilayers that surround the Golgi apparatus to form a single Golgi membrane.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2015-05-21T10:05:06Z") +AnnotationAssertion( "Golgi apparatus membrane fusion") +AnnotationAssertion(Annotation( "GOC:bf") "membrane fusion involved in Golgi reassembly") +AnnotationAssertion(Annotation( "PMID:10811609") "post-mitotic fusion of Golgi membranes") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0036504") +AnnotationAssertion(rdfs:label "Golgi membrane fusion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (astrocyte-dopaminergic neuron signaling) + +AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:bf") Annotation( "PMID:12794311") Annotation( "PMID:21752258") "Cell-cell signaling that mediates the transfer of information from an astrocyte to a dopaminergic neuron.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2016-02-29T14:05:47Z") +AnnotationAssertion(Annotation( "GOC:bf") "astrocyte-dopaminergic neuron cell signaling") +AnnotationAssertion(Annotation( "PMID:21752258") "mesencephalic dopaminergic neuron-astrocyte crosstalk") +AnnotationAssertion(Annotation( "PMID:21752258") "midbrain dopaminergic neuron-astrocyte crosstalk") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "PMID:21752258") "dopaminergic neuron-astrocyte crosstalk") +AnnotationAssertion( "GO:0036520") +AnnotationAssertion(rdfs:label "astrocyte-dopaminergic neuron signaling") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (signaling receptor activity) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:signaling") "Receiving a signal and transmitting it in the cell to initiate a change in cell activity. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-08-01T02:45:27Z") +AnnotationAssertion( "GO:0004872") +AnnotationAssertion( "GO:0019041") +AnnotationAssertion( "receptor activity") +AnnotationAssertion(Annotation( "GOC:bf") "receptor activity involved in signal transduction") +AnnotationAssertion( "signalling receptor activity") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0038023") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "signaling receptor activity") +SubClassOf( ) + +# Class: (prolactin signaling pathway) + +AnnotationAssertion(Annotation( "GOC:nhn") Annotation( "GOC:signaling") Annotation( "PMID:21664429") "The series of molecular signals initiated by the binding of the peptide hormone prolactin to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.") +AnnotationAssertion( ) +AnnotationAssertion( "bf") +AnnotationAssertion( "2012-05-14T01:52:59Z") +AnnotationAssertion(Annotation( "PMID:21664429") Annotation( "PR:000013246") "PRL signaling pathway") +AnnotationAssertion(Annotation( "GOC:bf") "prolactin-mediated signaling pathway") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0038161") +AnnotationAssertion(rdfs:label "prolactin signaling pathway") +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses( ObjectSomeValuesFrom( )) + +# Class: (somatostatin receptor signaling pathway) + +AnnotationAssertion(Annotation( "GOC:jc") Annotation( "PMID:18006219") Annotation( "PMID:8769369") "A G protein-coupled receptor signaling pathway initiated by somatostatin binding to the somatostatin receptor (SSTR) on the surface of a target cell, and ending with the regulation of a downstream cellular process.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2012-06-12T10:30:01Z") +AnnotationAssertion(Annotation( "GOC:bf") "SST receptor signaling pathway") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:bf") "SSTR signaling pathway") +AnnotationAssertion( "GO:0038169") +AnnotationAssertion(rdfs:comment "In addition to somatostatin (SST), the somatostatin receptors (SSTRs) can also be activated by the agonist cortistatin (CST). For signal transduction specifically initiated by the ligand somatostatin, consider instead annotating to the child term 'somatostatin signaling pathway ; GO:0038170'.") +AnnotationAssertion(rdfs:label "somatostatin receptor signaling pathway") +SubClassOf( ) + +# Class: (somatostatin signaling pathway) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:nhn") Annotation( "GOC:signaling") Annotation( "PMID:18006219") Annotation( "Wikipedia:Somatostatin") "A G protein-coupled receptor signaling pathway initiated by somatostatin binding to a somatostatin receptor (SSTR), and ending with the regulation of a downstream cellular process, e.g. transcription.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2012-06-12T10:33:21Z") +AnnotationAssertion(Annotation( "Wikipedia:Somatostatin") "SRIF signaling pathway") +AnnotationAssertion(Annotation( "Wikipedia:Somatostatin") "SST signaling pathway") +AnnotationAssertion(Annotation( "GOC:bf") "somatostatin signalling pathway") +AnnotationAssertion(Annotation( "GOC:bf") "somatostatin-activated somatostatin receptor signaling pathway") +AnnotationAssertion(Annotation( "GOC:bf") "somatostatin-mediated signaling pathway") +AnnotationAssertion(Annotation( "Wikipedia:Somatostatin") "somatotrophin release inhibiting factor signaling pathway") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0038170") +AnnotationAssertion(rdfs:label "somatostatin signaling pathway") +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (pattern recognition receptor activity) + +AnnotationAssertion(Annotation( "GOC:ar") Annotation( "GOC:bf") "Combining with a pathogen-associated molecular pattern (PAMP), a structure conserved among microbial species to initiate an innate immune response.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/17995"^^xsd:anyURI) +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/18588"^^xsd:anyURI) +AnnotationAssertion( "bf") +AnnotationAssertion( "2013-05-29T15:24:44Z") +AnnotationAssertion( "GO:0008329") +AnnotationAssertion( "Wikipedia:Pattern_recognition_receptor") +AnnotationAssertion( "PRR") +AnnotationAssertion(Annotation( "Wikipedia:Pattern_recognition_receptor") "PRR activity") +AnnotationAssertion( "MAMP receptor activity") +AnnotationAssertion( "PAMP receptor activity") +AnnotationAssertion( "microbe-associated molecular pattern receptor activity") +AnnotationAssertion( "pathogen associated molecular pattern receptor activity") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "macrophage receptor activity") +AnnotationAssertion( "signaling pattern recognition receptor activity") +AnnotationAssertion( "GO:0038187") +AnnotationAssertion(rdfs:label "pattern recognition receptor activity") +SubClassOf( ) + +# Class: (pronephric nephron tubule formation) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The developmental process pertaining to the initial formation of a pronephric nephron tubule from unspecified parts. A pronephric nephron tubule is an epithelial tube that is part of a nephron in the pronephros.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2010-07-02T09:37:27Z") +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "pronephric tubule formation") +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "pronephros tubule formation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0039006") +AnnotationAssertion(rdfs:label "pronephric nephron tubule formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (pronephric nephron morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the anatomical structures of the pronephric nephron are generated and organized. A pronephric nephron is the functional unit of the pronephros.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2010-07-02T09:38:53Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0039007") +AnnotationAssertion(rdfs:label "pronephric nephron morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (pronephric nephron tubule morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") Annotation( "ZFA:00001558") "The process in which the anatomical structures of a pronephric nephron tubule are generated and organized from an epithelium. A pronephric nephron tubule is an epithelial tube that is part of the pronephric nephron.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2010-07-02T09:45:55Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0039008") +AnnotationAssertion(rdfs:label "pronephric nephron tubule morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (rectal diverticulum development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") Annotation( "PMID:10535314") Annotation( "PMID:18226983") Annotation( "XAO:0001015") "The process whose specific outcome is the progression of the rectal diverticulum over time, from its formation to the mature structure. The rectal diverticulum is an outgrowth of the cloaca and links the pronephric kidney to the exterior.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2010-07-02T09:48:58Z") +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "pronephric rectal diverticulum development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0039009") +AnnotationAssertion(rdfs:label "rectal diverticulum development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (pronephric proximal tubule morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the anatomical structures of a pronephric nephron proximal tubule are generated and organized. A pronephric nephron tubule is an epithelial tube that is part of the pronephros.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2010-07-02T09:53:12Z") +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "pronephros proximal tubule morphogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0039011") +AnnotationAssertion(rdfs:label "pronephric proximal tubule morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (pronephric distal tubule morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the anatomical structures of a pronephric nephron distal tubule are generated and organized. A pronephric nephron tubule is an epithelial tube that is part of the pronephros.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2010-07-02T09:58:03Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0039013") +AnnotationAssertion(rdfs:label "pronephric distal tubule morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cell differentiation involved in pronephros development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the pronephros as it progresses from its formation to the mature state.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2010-07-02T09:59:25Z") +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "cell differentiation involved in pronephric kidney development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0039014") +AnnotationAssertion(rdfs:label "cell differentiation involved in pronephros development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (cell proliferation involved in pronephros development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The multiplication or reproduction of cells, resulting in the expansion of the population in the pronephros.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2010-07-02T10:01:49Z") +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "cell proliferation involved in pronephric kidney development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0039015") +AnnotationAssertion(rdfs:label "cell proliferation involved in pronephros development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (cell-cell signaling involved in pronephros development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "Any process that mediates the transfer of information from one cell to another and contributes to the progression of the pronephros over time, from its formation to the mature organ.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2010-07-02T10:03:16Z") +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "cell-cell signaling involved in pronephric kidney development") +AnnotationAssertion(Annotation( "GOC:mah") "cell-cell signalling involved in pronephros development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0039016") +AnnotationAssertion(rdfs:label "cell-cell signaling involved in pronephros development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (pattern specification involved in pronephros development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "Any developmental process that results in the creation of defined areas or spaces within the pronephros to which cells respond and eventually are instructed to differentiate.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2010-07-02T10:04:39Z") +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "pattern specification involved in pronephric kidney development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0039017") +AnnotationAssertion(rdfs:label "pattern specification involved in pronephros development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (nephrostome development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") Annotation( "PMID:14686690") Annotation( "PMID:15647339") Annotation( "XAO:0000062") "The process whose specific outcome is the progression of the nephrostome over time, from its formation to the mature structure. The nephrostome is the opening of the pronephros into the body cavity.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2010-07-02T10:08:16Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0039018") +AnnotationAssertion(rdfs:label "nephrostome development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (pronephric nephron development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") Annotation( "XAO:00002785") "The process whose specific outcome is the progression of the pronephric nephron over time, from its formation to the mature structure. A pronephric nephron is the functional unit of the pronephros.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2010-07-02T10:10:20Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0039019") +AnnotationAssertion(rdfs:label "pronephric nephron development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (pronephric nephron tubule development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") Annotation( "PMID:19909807") Annotation( "PMID:9268568") "The process whose specific outcome is the progression of a pronephric nephron tubule over time, from its formation to the mature structure. The pronephric nephron tubule is an epithelial tube that is part of the pronephric nephron and connects the filtration unit (glomerulus or glomus) of the pronephros to the pronephric duct.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2010-07-02T10:11:36Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0039020") +AnnotationAssertion(rdfs:label "pronephric nephron tubule development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (pronephric glomerulus development) + +AnnotationAssertion(Annotation( "GOC:dgh") Annotation( "GOC:mtg_kidney_jan10") Annotation( "ZFA:00001557") "The progression of the glomerulus of the pronephric kidney over time from its initial formation until its mature state. The pronephric glomerulus is part of the pronephric nephron and is restricted to one body segment.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2010-07-02T10:13:38Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0039021") +AnnotationAssertion(rdfs:comment "This term is intended for annotation of fish and other organisms which contain a glomerulus as part of the pronephric nephron. It should not be used for annotation of Xenopus, which contains a pronephric glomus rather than a glomerulus.") +AnnotationAssertion(rdfs:label "pronephric glomerulus development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (pronephric duct development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") Annotation( "PMID:15647339") Annotation( "XAO:0000063") Annotation( "ZFA:0000150") "The process whose specific outcome is the progression of the pronephric duct over time, from its formation to the mature structure. The pronephric duct collects the filtrate from the pronephric tubules and opens to the exterior of the pronephric kidney.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2010-07-02T10:15:03Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0039022") +AnnotationAssertion(rdfs:label "pronephric duct development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (pronephric duct morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") Annotation( "XAO:0000063") Annotation( "ZFA:0000150") "The process in which the anatomical structures of the pronephric duct are generated and organized. The pronephric duct collects the filtrate from the pronephric tubules and opens to the exterior of the kidney.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2010-07-02T10:18:09Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0039023") +AnnotationAssertion(rdfs:label "pronephric duct morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (collagen and cuticulin-based cuticle development) + +AnnotationAssertion(Annotation( "GOC:mtg_sensu") "Synthesis and deposition of a collagen and cuticulin-based noncellular, hardened, or membranous secretion from an epithelial sheet. An example of this process is found in Caenorhabditis elegans.") +AnnotationAssertion( "collagen and cuticulin-based cuticle anabolism") +AnnotationAssertion( "collagen and cuticulin-based cuticle biosynthetic process") +AnnotationAssertion( "collagen and cuticulin-based cuticle formation") +AnnotationAssertion( "collagen and cuticulin-based cuticle synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0040002") +AnnotationAssertion(rdfs:label "collagen and cuticulin-based cuticle development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectAllValuesFrom( )) + +# Class: (chitin-based cuticle development) + +AnnotationAssertion(Annotation( "GOC:mtg_sensu") "Synthesis and deposition of a chitin-based noncellular, hardened, or membranous secretion from an epithelial sheet. An example of this process is found in Drosophila melanogaster.") +AnnotationAssertion( "chitin-based cuticle anabolism") +AnnotationAssertion( "chitin-based cuticle biosynthetic process") +AnnotationAssertion( "chitin-based cuticle formation") +AnnotationAssertion( "chitin-based cuticle synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0040003") +AnnotationAssertion(rdfs:label "chitin-based cuticle development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectAllValuesFrom( )) + # Class: (growth) AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:ma") "The increase in size or mass of an entire organism, a part of an organism or a cell.") @@ -35387,6 +79431,15 @@ SubClassOf( ObjectSomeValuesFrom( ObjectAllValuesFrom( )) DisjointClasses( ) +# Class: (regulation of growth) + +AnnotationAssertion(Annotation( "GOC:ems") Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the growth of all or part of an organism so that it occurs at its proper speed, either globally or in a specific part of the organism's development.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0040008") +AnnotationAssertion(rdfs:label "regulation of growth") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + # Class: (locomotion) AnnotationAssertion(Annotation( "GOC:dgh") "Self-propelled movement of a cell or organism from one location to another.") @@ -35408,8 +79461,43 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:0040012") AnnotationAssertion(rdfs:label "regulation of locomotion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (negative regulation of locomotion) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of locomotion of a cell or organism.") +AnnotationAssertion( "down regulation of locomotion") +AnnotationAssertion( "down-regulation of locomotion") +AnnotationAssertion( "downregulation of locomotion") +AnnotationAssertion( "inhibition of locomotion") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0040013") +AnnotationAssertion(rdfs:label "negative regulation of locomotion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of multicellular organism growth) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:ems") Annotation( "GOC:tb") "Any process that modulates the frequency, rate or extent of growth of the body of an organism so that it reaches its usual body size.") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "regulation of body growth") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "regulation of body size") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0040014") +AnnotationAssertion(rdfs:label "regulation of multicellular organism growth") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of multicellular organism growth) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:ems") Annotation( "GOC:tb") "Any process that stops, prevents, or reduces the frequency, rate or extent of growth of an organism to reach its usual body size.") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "negative regulation of body growth") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "negative regulation of body size") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0040015") +AnnotationAssertion(rdfs:label "negative regulation of multicellular organism growth") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (embryonic cleavage) AnnotationAssertion(Annotation( "GOC:clt") Annotation( "ISBN:0070524300") "The first few specialized divisions of an activated animal egg.") @@ -35430,9 +79518,58 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0040017") AnnotationAssertion(rdfs:label "positive regulation of locomotion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) +# Class: (positive regulation of multicellular organism growth) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:go_curators") Annotation( "GOC:tb") "Any process that activates or increases the frequency, rate or extent of growth of an organism to reach its usual body size.") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "positive regulation of body growth") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "positive regulation of body size") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0040018") +AnnotationAssertion(rdfs:label "positive regulation of multicellular organism growth") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of embryonic development) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of embryonic development.") +AnnotationAssertion( "up regulation of embryonic development") +AnnotationAssertion( "up-regulation of embryonic development") +AnnotationAssertion( "upregulation of embryonic development") +AnnotationAssertion( "activation of embryonic development") +AnnotationAssertion( "stimulation of embryonic development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0040019") +AnnotationAssertion(rdfs:label "positive regulation of embryonic development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of meiotic nuclear division) + +AnnotationAssertion(Annotation( "GOC:ems") Annotation( "GOC:ma") "Any process that modulates the frequency, rate or extent of meiotic nuclear division, the process in which the nucleus of a diploid cell divides twice forming four haploid cells, one or more of which usually function as gametes.") +AnnotationAssertion(Annotation( "GOC:vw") "regulation of meiosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0040020") +AnnotationAssertion(rdfs:label "regulation of meiotic nuclear division") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (regulation of development, heterochronic) + +AnnotationAssertion(Annotation( "PMID:9442909") "Any process that modulates the consistent predetermined time point at which an integrated living unit or organism progresses from an initial condition to a later condition and the rate at which this time point is reached.") +AnnotationAssertion( "heterochronic regulation of development") +AnnotationAssertion( "temporal regulation of development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "developmental timing") +AnnotationAssertion( "GO:0040034") +AnnotationAssertion(rdfs:label "regulation of development, heterochronic") +SubClassOf( ) + # Class: (fluid transport) AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of substances that are in liquid form in normal living conditions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") @@ -35442,6 +79579,14 @@ AnnotationAssertion( "fluid transport") SubClassOf( ) +# Class: (epithelial fluid transport) + +AnnotationAssertion(Annotation( "GOC:jl") Annotation( "PMID:11390830") "The directed movement of fluid across epithelia.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042045") +AnnotationAssertion(rdfs:label "epithelial fluid transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (olfactory behavior) AnnotationAssertion(Annotation( "GOC:jid") Annotation( "GOC:pr") "The behavior of an organism in response to an odor.") @@ -35456,6 +79601,15 @@ AnnotationAssertion( "olfactory behavior") SubClassOf( ) +# Class: (regulation of dopamine metabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving dopamine.") +AnnotationAssertion( "regulation of dopamine metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042053") +AnnotationAssertion(rdfs:label "regulation of dopamine metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (wound healing) AnnotationAssertion(Annotation( "GOC:bf") Annotation( "PMID:15269788") "The series of events that restore integrity to a damaged tissue, following an injury.") @@ -35467,6 +79621,124 @@ AnnotationAssertion(rdfs:label "woun SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (gliogenesis) + +AnnotationAssertion(Annotation( "GOC:dgh") Annotation( "GOC:jid") "The process that results in the generation of glial cells. This includes the production of glial progenitors and their differentiation into mature glia.") +AnnotationAssertion(Annotation( ) "glial cell generation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042063") +AnnotationAssertion(rdfs:label "gliogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (glial cell growth) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:isa_complete") Annotation( "GOC:jid") "Growth of glial cells, non-neuronal cells that provide support and nutrition, maintain homeostasis, form myelin, and participate in signal transmission in the nervous system.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042065") +AnnotationAssertion(rdfs:label "glial cell growth") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (regulation of catecholamine metabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving catecholamines.") +AnnotationAssertion( "regulation of catecholamine metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042069") +AnnotationAssertion(rdfs:label "regulation of catecholamine metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (intraciliary transport) + +AnnotationAssertion(Annotation( "GOC:cilia") Annotation( "GOC:kmv") Annotation( "PMID:17981739") Annotation( "PMID:18180368") Annotation( "PMID:22869374") Annotation( "Reactome:R-HSA-5620924.2") "The bidirectional movement of large protein complexes along microtubules within a cilium, mediated by motor proteins.") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( "GO:0035734") +AnnotationAssertion( "Wikipedia:Intraflagellar_transport") +AnnotationAssertion( "intraflagellar transport") +AnnotationAssertion( "intraflagellar transport involved in cilium organization") +AnnotationAssertion( "intraflagellar transport involved in microtubule-based flagellum organisation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "IFT") +AnnotationAssertion( "GO:0042073") +AnnotationAssertion(rdfs:comment "Note that we deem cilium and microtubule-based flagellum to be equivalent.") +AnnotationAssertion(rdfs:label "intraciliary transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) +SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) +SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) +SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) +SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) +SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) +SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) +SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) +SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) +SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) +SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) +SubClassOf( ObjectAllValuesFrom( )) +DisjointClasses( ObjectSomeValuesFrom( )) +DisjointClasses( ObjectSomeValuesFrom( )) +DisjointClasses( ObjectSomeValuesFrom( )) +DisjointClasses( ObjectSomeValuesFrom( )) +DisjointClasses( ObjectSomeValuesFrom( )) +DisjointClasses( ObjectSomeValuesFrom( )) + +# Class: (cell migration involved in gastrulation) + +AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0878932437") Annotation( "http://www.cellmigration.org/") "The migration of individual cells within the blastocyst to help establish the multi-layered body plan of the organism (gastrulation). For example, the migration of cells from the surface to the interior of the embryo (ingression).") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042074") +AnnotationAssertion(rdfs:label "cell migration involved in gastrulation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (germ-line stem cell division) + +AnnotationAssertion(Annotation( "GOC:jid") Annotation( "PMID:2279698") "The self-renewing division of a germline stem cell to produce a daughter stem cell and a daughter germ cell, which will divide to form the gametes.") +AnnotationAssertion( "GO:0048131") +AnnotationAssertion( "germ-line stem cell renewal") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042078") +AnnotationAssertion(rdfs:label "germ-line stem cell division") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (type 2 immune response) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") Annotation( "PMID:18000958") Annotation( "PMID:18007680") Annotation( "PMID:20065995") Annotation( "PMID:20200518") "An immune response which is associated with resistance to extracellular organisms such as helminths and pathological conditions such as allergy, which is orchestrated by the production of particular cytokines, most notably IL-4, IL-5, IL-10, and IL-13, by any of a variety of cell types including T-helper 2 cells, eosinophils, basophils, mast cells, and nuocytes, resulting in enhanced production of certain antibody isotypes and other effects.") +AnnotationAssertion(Annotation( "GOC:add") "T-helper 2 type immune response") +AnnotationAssertion(Annotation( "GOC:add") "Th2 immune response") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042092") +AnnotationAssertion(rdfs:label "type 2 immune response") +SubClassOf( ) + +# Class: (T cell proliferation) + +AnnotationAssertion(Annotation( "GOC:jl") "The expansion of a T cell population by cell division. Follows T cell activation.") +AnnotationAssertion( "GO:0042111") +AnnotationAssertion( "T lymphocyte proliferation") +AnnotationAssertion( "T-cell proliferation") +AnnotationAssertion( "T-lymphocyte proliferation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042098") +AnnotationAssertion(rdfs:label "T cell proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + # Class: (B cell proliferation) AnnotationAssertion(Annotation( "GOC:jl") "The expansion of a B cell population by cell division. Follows B cell activation.") @@ -35477,9 +79749,42 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0042100") AnnotationAssertion(rdfs:label "B cell proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) +# Class: (positive regulation of T cell proliferation) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the rate or extent of T cell proliferation.") +AnnotationAssertion( "positive regulation of T lymphocyte proliferation") +AnnotationAssertion( "positive regulation of T-lymphocyte proliferation") +AnnotationAssertion( "up regulation of T cell proliferation") +AnnotationAssertion( "up-regulation of T cell proliferation") +AnnotationAssertion( "upregulation of T cell proliferation") +AnnotationAssertion( "activation of T cell proliferation") +AnnotationAssertion( "stimulation of T cell proliferation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042102") +AnnotationAssertion(rdfs:label "positive regulation of T cell proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of T cell homeostatic proliferation) + +AnnotationAssertion(Annotation( "GOC:jl") "Any process that activates or increases the rate or extent of resting T cell proliferation.") +AnnotationAssertion( "positive regulation of T lymphocyte homeostatic proliferation") +AnnotationAssertion( "positive regulation of T-cell homeostatic proliferation") +AnnotationAssertion( "positive regulation of T-lymphocyte homeostatic proliferation") +AnnotationAssertion( "positive regulation of resting T cell proliferation") +AnnotationAssertion( "up regulation of T cell homeostatic proliferation") +AnnotationAssertion( "up-regulation of T cell homeostatic proliferation") +AnnotationAssertion( "upregulation of T cell homeostatic proliferation") +AnnotationAssertion( "activation of T cell homeostatic proliferation") +AnnotationAssertion( "stimulation of T cell homeostatic proliferation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042103") +AnnotationAssertion(rdfs:label "positive regulation of T cell homeostatic proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (T cell activation) AnnotationAssertion(Annotation( "GOC:mgi_curators") Annotation( "ISBN:0781735149") "The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.") @@ -35489,6 +79794,7 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0042110") AnnotationAssertion(rdfs:label "T cell activation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) # Class: (B cell activation) @@ -35500,8 +79806,45 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0042113") AnnotationAssertion(rdfs:label "B cell activation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (macrophage activation) + +AnnotationAssertion(Annotation( "GOC:mgi_curators") Annotation( "ISBN:0781735149") Annotation( "PMID:14506301") "A change in morphology and behavior of a macrophage resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.") +AnnotationAssertion( "macrophage polarization") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042116") +AnnotationAssertion(rdfs:label "macrophage activation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (monocyte activation) + +AnnotationAssertion(Annotation( "GOC:mgi_curators") Annotation( "ISBN:0781735149") "The change in morphology and behavior of a monocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042117") +AnnotationAssertion(rdfs:label "monocyte activation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (endothelial cell activation) + +AnnotationAssertion(Annotation( "GOC:mgi_curators") Annotation( "ISBN:0781735149") Annotation( "PMID:12851652") Annotation( "PMID:14581484") "The change in morphology and behavior of an endothelial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042118") +AnnotationAssertion(rdfs:label "endothelial cell activation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (neutrophil activation) + +AnnotationAssertion(Annotation( "GOC:mgi_curators") Annotation( "ISBN:0781735149") "The change in morphology and behavior of a neutrophil resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042119") +AnnotationAssertion(rdfs:label "neutrophil activation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (regulation of cell population proliferation) AnnotationAssertion(Annotation( "GOC:jl") "Any process that modulates the frequency, rate or extent of cell proliferation.") @@ -35510,6 +79853,7 @@ AnnotationAssertion( "regulation of cell proliferation") AnnotationAssertion( "GO:0042127") AnnotationAssertion(rdfs:label "regulation of cell population proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) @@ -35541,49 +79885,6 @@ AnnotationAssertion( "negative regulation of T cell proliferation") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -# Class: (neurotransmitter metabolic process) - -AnnotationAssertion(Annotation( "GOC:jl") "The chemical reactions and pathways involving neurotransmitters, any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell.") -AnnotationAssertion( ) -AnnotationAssertion( "neurotransmitter metabolism") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042133") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "neurotransmitter metabolic process") -SubClassOf( ) -SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) -SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) -DisjointClasses( ObjectSomeValuesFrom( )) - -# Class: (neurotransmitter catabolic process) - -AnnotationAssertion(Annotation( "GOC:jl") "The chemical reactions and pathways resulting in the breakdown of any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell.") -AnnotationAssertion( "neurotransmitter breakdown") -AnnotationAssertion( "neurotransmitter catabolism") -AnnotationAssertion( "neurotransmitter degradation") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042135") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "neurotransmitter catabolic process") -SubClassOf( ) -SubClassOf( ) - -# Class: (neurotransmitter biosynthetic process) - -AnnotationAssertion(Annotation( "GOC:jl") "The chemical reactions and pathways resulting in the formation of any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell.") -AnnotationAssertion( "neurotransmitter biosynthesis and storage") -AnnotationAssertion( "neurotransmitter biosynthetic process and storage") -AnnotationAssertion( "neurotransmitter anabolism") -AnnotationAssertion( "neurotransmitter biosynthesis") -AnnotationAssertion( "neurotransmitter formation") -AnnotationAssertion( "neurotransmitter synthesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0042136") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "neurotransmitter biosynthetic process") -SubClassOf( ) -SubClassOf( ) - # Class: (lipoprotein metabolic process) AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving any conjugated, water-soluble protein in which the covalently attached nonprotein group consists of a lipid or lipids.") @@ -35618,15 +79919,6 @@ AnnotationAssertion( "lipoprotein catabolic process") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -# Class: (neurotransmitter binding) - -AnnotationAssertion(Annotation( "ISBN:0198506732") "Binding to a neurotransmitter, any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell.") -AnnotationAssertion( "molecular_function") -AnnotationAssertion( "GO:0042165") -AnnotationAssertion( ) -AnnotationAssertion(rdfs:label "neurotransmitter binding") -SubClassOf( ) - # Class: (acetylcholine binding) AnnotationAssertion(Annotation( "GOC:ai") "Binding to acetylcholine, an acetic acid ester of the organic base choline that functions as a neurotransmitter, released at the synapses of parasympathetic nerves and at neuromuscular junctions.") @@ -35634,7 +79926,6 @@ AnnotationAssertion( "GO:0042166") AnnotationAssertion(rdfs:label "acetylcholine binding") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) # Class: (nuclear outer membrane-endoplasmic reticulum membrane network) @@ -35723,6 +80014,7 @@ AnnotationAssertion( "GO:0042180") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "cellular ketone metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ) @@ -35738,11 +80030,65 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0042181") AnnotationAssertion(rdfs:label "ketone biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) +# Class: (ketone catabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways resulting in the breakdown of ketones, a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups.") +AnnotationAssertion( "ketone breakdown") +AnnotationAssertion( "ketone catabolism") +AnnotationAssertion( "ketone degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042182") +AnnotationAssertion(rdfs:label "ketone catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (formate catabolic process) + +AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of formate, also known as methanoate, the anion HCOO- derived from methanoic (formic) acid.") +AnnotationAssertion( "formate breakdown") +AnnotationAssertion( "formate catabolism") +AnnotationAssertion( "formate degradation") +AnnotationAssertion( "formic acid catabolic process") +AnnotationAssertion( "formic acid catabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042183") +AnnotationAssertion(rdfs:label "formate catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (terpene metabolic process) + +AnnotationAssertion(Annotation( "GOC:curators") "The chemical reactions and pathways involving terpenes, any of a large group of hydrocarbons that are made up of isoprene (C5H8) units which may be cyclic, acyclic or multicyclic, saturated or unsaturated, and may contain various functional groups.") +AnnotationAssertion( "terpene metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042214") +AnnotationAssertion(rdfs:label "terpene metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (cellular modified amino acid catabolic process) + +AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways resulting in the breakdown of compounds derived from amino acids, organic acids containing one or more amino substituents.") +AnnotationAssertion( "amino acid derivative catabolic process") +AnnotationAssertion( "cellular amino acid derivative breakdown") +AnnotationAssertion( "cellular amino acid derivative catabolic process") +AnnotationAssertion( "cellular amino acid derivative catabolism") +AnnotationAssertion( "cellular amino acid derivative degradation") +AnnotationAssertion(Annotation( "GOC:mah") "cellular modified amino acid breakdown") +AnnotationAssertion(Annotation( "GOC:mah") "cellular modified amino acid catabolism") +AnnotationAssertion(Annotation( "GOC:mah") "cellular modified amino acid degradation") +AnnotationAssertion(Annotation( "GOC:mah") "modified amino acid catabolic process") +AnnotationAssertion(Annotation( "GOC:mah") "modified amino acid catabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042219") +AnnotationAssertion(rdfs:label "cellular modified amino acid catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (response to chemical) AnnotationAssertion(Annotation( "GOC:jl") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus.") @@ -35758,6 +80104,7 @@ AnnotationAssertion( ) AnnotationAssertion(rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.") AnnotationAssertion(rdfs:label "response to chemical") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) # Class: (tissue regeneration) @@ -35767,12 +80114,72 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0042246") AnnotationAssertion(rdfs:label "tissue regeneration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) DisjointClasses( ObjectSomeValuesFrom( )) +# Class: (ribosome biogenesis) + +AnnotationAssertion(Annotation( "GOC:ma") Annotation( "PMID:26404467") Annotation( "Wikipedia:Ribosome_biogenesis") "A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits; includes transport to the sites of protein synthesis.") +AnnotationAssertion( "GO:0007046") +AnnotationAssertion( "ribosome biogenesis and assembly") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042254") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "ribosome biogenesis") +SubClassOf( ) + +# Class: (ribosome assembly) + +AnnotationAssertion(Annotation( "GOC:ma") Annotation( "PMID:30467428") "The aggregation, arrangement and bonding together of the mature ribosome and of its subunits.") +AnnotationAssertion( "GO:0042257") +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:vw") "ribosomal subunit assembly") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042255") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "ribosome assembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (peptide binding) + +AnnotationAssertion(Annotation( "GOC:jl") "Binding to a peptide, an organic compound comprising two or more amino acids linked by peptide bonds.") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0042277") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "peptide binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (purine nucleoside metabolic process) + +AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0140512713") "The chemical reactions and pathways involving one of a family of organic molecules consisting of a purine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside).") +AnnotationAssertion( "purine metabolic process") +AnnotationAssertion( "purine metabolism") +AnnotationAssertion( "purine nucleoside metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042278") +AnnotationAssertion(rdfs:label "purine nucleoside metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (phosphate ion binding) + +AnnotationAssertion(Annotation( "GOC:jl") "Binding to a phosphate ion.") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0042301") +AnnotationAssertion(rdfs:label "phosphate ion binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (molting cycle) AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0198506732") "The periodic casting off and regeneration of an outer covering of cuticle, feathers, hair, horns, skin, etc.") @@ -35783,6 +80190,215 @@ AnnotationAssertion( "molting cycle") SubClassOf( ) +# Class: (regulation of fatty acid biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "GOC:jl") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fatty acids, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils.") +AnnotationAssertion( "regulation of fatty acid anabolism") +AnnotationAssertion( "regulation of fatty acid biosynthesis") +AnnotationAssertion( "regulation of fatty acid formation") +AnnotationAssertion( "regulation of fatty acid synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042304") +AnnotationAssertion(rdfs:label "regulation of fatty acid biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of protein import into nucleus) + +AnnotationAssertion(Annotation( "GOC:jl") "Any process that modulates the frequency, rate or extent of movement of proteins from the cytoplasm to the nucleus.") +AnnotationAssertion( "regulation of protein import into cell nucleus") +AnnotationAssertion( "regulation of protein transport from cytoplasm to nucleus") +AnnotationAssertion( "regulation of protein-nucleus import") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042306") +AnnotationAssertion(rdfs:label "regulation of protein import into nucleus") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of protein import into nucleus) + +AnnotationAssertion(Annotation( "GOC:jl") "Any process that activates or increases the frequency, rate or extent of movement of proteins from the cytoplasm into the nucleus.") +AnnotationAssertion( "positive regulation of protein import into cell nucleus") +AnnotationAssertion( "positive regulation of protein transport from cytoplasm to nucleus") +AnnotationAssertion( "positive regulation of protein-nucleus import") +AnnotationAssertion( "up regulation of protein import into nucleus") +AnnotationAssertion( "up-regulation of protein import into nucleus") +AnnotationAssertion( "upregulation of protein import into nucleus") +AnnotationAssertion( "activation of protein import into nucleus") +AnnotationAssertion( "stimulation of protein import into nucleus") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042307") +AnnotationAssertion(rdfs:label "positive regulation of protein import into nucleus") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of protein import into nucleus) + +AnnotationAssertion(Annotation( "GOC:jl") "Any process that stops, prevents, or reduces the frequency, rate or extent of the movement of proteins from the cytoplasm into the nucleus.") +AnnotationAssertion( "down regulation of protein import into nucleus") +AnnotationAssertion( "down-regulation of protein import into nucleus") +AnnotationAssertion( "downregulation of protein import into nucleus") +AnnotationAssertion( "negative regulation of protein import into cell nucleus") +AnnotationAssertion( "negative regulation of protein transport from cytoplasm to nucleus") +AnnotationAssertion( "negative regulation of protein-nucleus import") +AnnotationAssertion( "inhibition of protein import into nucleus") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042308") +AnnotationAssertion(rdfs:label "negative regulation of protein import into nucleus") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of circadian sleep/wake cycle, sleep) + +AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "GOC:jl") Annotation( "ISBN:0192800981") "Any process that stops, prevents or reduces the duration or quality of sleep, a readily reversible state of reduced awareness and metabolic activity that occurs periodically in many animals.") +AnnotationAssertion( "down regulation of circadian sleep/wake cycle, sleep") +AnnotationAssertion( "down-regulation of circadian sleep/wake cycle, sleep") +AnnotationAssertion( "downregulation of circadian sleep/wake cycle, sleep") +AnnotationAssertion( "negative regulation of sleep") +AnnotationAssertion( "inhibition of circadian sleep/wake cycle, sleep") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042321") +AnnotationAssertion(rdfs:label "negative regulation of circadian sleep/wake cycle, sleep") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of circadian sleep/wake cycle, non-REM sleep) + +AnnotationAssertion(Annotation( "GOC:jl") "Any process that stops, prevents or reduces the duration or quality of non-rapid eye movement (NREM) sleep.") +AnnotationAssertion( "down regulation of circadian sleep/wake cycle, non-REM sleep") +AnnotationAssertion( "down-regulation of circadian sleep/wake cycle, non-REM sleep") +AnnotationAssertion( "downregulation of circadian sleep/wake cycle, non-REM sleep") +AnnotationAssertion( "negative regulation of non-REM sleep") +AnnotationAssertion( "inhibition of circadian sleep/wake cycle, non-REM sleep") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042323") +AnnotationAssertion(rdfs:label "negative regulation of circadian sleep/wake cycle, non-REM sleep") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of phosphorylation) + +AnnotationAssertion(Annotation( "GOC:jl") "Any process that modulates the frequency, rate or extent of addition of phosphate groups into a molecule.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042325") +AnnotationAssertion(rdfs:label "regulation of phosphorylation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of phosphorylation) + +AnnotationAssertion(Annotation( "GOC:jl") "Any process that stops, prevents or decreases the rate of addition of phosphate groups to a molecule.") +AnnotationAssertion( "down regulation of phosphorylation") +AnnotationAssertion( "down-regulation of phosphorylation") +AnnotationAssertion( "downregulation of phosphorylation") +AnnotationAssertion( "inhibition of phosphorylation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042326") +AnnotationAssertion(rdfs:label "negative regulation of phosphorylation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of phosphorylation) + +AnnotationAssertion(Annotation( "GOC:jl") "Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to a molecule.") +AnnotationAssertion( "up regulation of phosphorylation") +AnnotationAssertion( "up-regulation of phosphorylation") +AnnotationAssertion( "upregulation of phosphorylation") +AnnotationAssertion( "activation of phosphorylation") +AnnotationAssertion( "stimulation of phosphorylation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042327") +AnnotationAssertion(rdfs:label "positive regulation of phosphorylation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (taxis) + +AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0192801023") "The directed movement of a motile cell or organism in response to an external stimulus.") +AnnotationAssertion( "Wikipedia:Taxis") +AnnotationAssertion( "directed movement in response to stimulus") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042330") +AnnotationAssertion(rdfs:label "taxis") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cuticle development) + +AnnotationAssertion(Annotation( "ISBN:0192800825") "The chemical reactions and pathways resulting in the formation of a cuticle, the outer layer of some animals and plants, which acts to prevent water loss.") +AnnotationAssertion( "cuticle anabolism") +AnnotationAssertion( "cuticle biosynthesis") +AnnotationAssertion( "cuticle biosynthetic process") +AnnotationAssertion( "cuticle formation") +AnnotationAssertion( "cuticle synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042335") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "cuticle development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cuticle development involved in chitin-based cuticle molting cycle) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:jl") Annotation( "GOC:mtg_sensu") Annotation( "GOC:tb") "The synthesis and deposition of a chitin-based non-cellular, hardened, or membranous secretion from an epithelial sheet, occurring as part of the molting cycle. An example of this is found in Drosophila melanogaster.") +AnnotationAssertion( "cuticle anabolism during molting") +AnnotationAssertion( "cuticle biosynthetic process during molting") +AnnotationAssertion( "cuticle formation during molting") +AnnotationAssertion( "cuticle synthesis during molting") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "chitin-based cuticle development during molting") +AnnotationAssertion( "GO:0042337") +AnnotationAssertion(rdfs:label "cuticle development involved in chitin-based cuticle molting cycle") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (keratan sulfate metabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways involving keratan sulfate, a glycosaminoglycan with repeat units consisting of beta-1,4-linked D-galactopyranosyl-beta-(1,4)-N-acetyl-D-glucosamine 6-sulfate and with variable amounts of fucose, sialic acid and mannose units; keratan sulfate chains are covalently linked by a glycosidic attachment through the trisaccharide galactosyl-galactosyl-xylose to peptidyl-threonine or serine residues.") +AnnotationAssertion( "keratan sulfate metabolism") +AnnotationAssertion( "keratan sulphate metabolic process") +AnnotationAssertion( "keratan sulphate metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042339") +AnnotationAssertion(rdfs:label "keratan sulfate metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (keratan sulfate catabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways resulting in the breakdown of keratan sulfate, a glycosaminoglycan with repeat units consisting of beta-1,4-linked D-galactopyranosyl-beta-(1,4)-N-acetyl-D-glucosamine 6-sulfate and with variable amounts of fucose, sialic acid and mannose units; keratan sulfate chains are covalently linked by a glycosidic attachment through the trisaccharide galactosyl-galactosyl-xylose to peptidyl-threonine or serine residues.") +AnnotationAssertion( "keratan sulfate breakdown") +AnnotationAssertion( "keratan sulfate catabolism") +AnnotationAssertion( "keratan sulfate degradation") +AnnotationAssertion( "keratan sulphate catabolic process") +AnnotationAssertion( "keratan sulphate catabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042340") +AnnotationAssertion(rdfs:label "keratan sulfate catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (chemokine receptor binding) + +AnnotationAssertion(Annotation( "GOC:ai") "Binding to a chemokine receptor.") +AnnotationAssertion( "chemokine receptor ligand") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0042379") +AnnotationAssertion(rdfs:label "chemokine receptor binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (hemocyte differentiation) + +AnnotationAssertion(Annotation( "CL:0000387") Annotation( "GOC:jl") Annotation( "GOC:mtg_sensu") Annotation( "PMID:9550723") "The process in which a relatively unspecialized cell acquires the characteristics of a mature hemocyte. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen.") +AnnotationAssertion( "arthropod blood cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042386") +AnnotationAssertion(rdfs:label "hemocyte differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectAllValuesFrom( )) + # Class: (regulation of membrane potential) AnnotationAssertion(Annotation( "GOC:jl") Annotation( "GOC:mtg_cardio") Annotation( "GOC:tb") Annotation( "ISBN:0198506732") "Any process that modulates the establishment or extent of a membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.") @@ -35791,6 +80407,49 @@ AnnotationAssertion( "regulation of membrane potential") SubClassOf( ObjectSomeValuesFrom( )) +# Class: (cellular modified amino acid biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways resulting in the formation of compounds derived from amino acids, organic acids containing one or more amino substituents.") +AnnotationAssertion( "amino acid derivative biosynthetic process") +AnnotationAssertion( "cellular amino acid derivative anabolism") +AnnotationAssertion( "cellular amino acid derivative biosynthesis") +AnnotationAssertion( "cellular amino acid derivative biosynthetic process") +AnnotationAssertion( "cellular amino acid derivative formation") +AnnotationAssertion( "cellular amino acid derivative synthesis") +AnnotationAssertion(Annotation( "GOC:mah") "cellular modified amino acid anabolism") +AnnotationAssertion(Annotation( "GOC:mah") "cellular modified amino acid biosynthesis") +AnnotationAssertion(Annotation( "GOC:mah") "cellular modified amino acid formation") +AnnotationAssertion(Annotation( "GOC:mah") "cellular modified amino acid synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042398") +AnnotationAssertion(rdfs:label "cellular modified amino acid biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (biogenic amine biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0395825172") "The chemical reactions and pathways occurring at the level of individual cells resulting in the formation of any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters.") +AnnotationAssertion( "biogenic amine anabolism") +AnnotationAssertion( "biogenic amine biosynthesis") +AnnotationAssertion( "biogenic amine formation") +AnnotationAssertion( "biogenic amine synthesis") +AnnotationAssertion( "cellular biogenic amine biosynthetic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042401") +AnnotationAssertion(rdfs:label "biogenic amine biosynthetic process") +SubClassOf( ) +SubClassOf( ) + +# Class: (cellular biogenic amine catabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "GOC:jl") Annotation( "ISBN:0198506732") "The chemical reactions and pathways occurring at the level of individual cells resulting in the breakdown of biogenic amines, any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters.") +AnnotationAssertion( "biogenic amine breakdown") +AnnotationAssertion( "biogenic amine catabolism") +AnnotationAssertion( "biogenic amine degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042402") +AnnotationAssertion(rdfs:label "cellular biogenic amine catabolic process") +SubClassOf( ) + # Class: (thyroid hormone metabolic process) AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving any of the compounds secreted by the thyroid gland, largely thyroxine and triiodothyronine.") @@ -35802,6 +80461,186 @@ SubClassOf( ) SubClassOf( ) +# Class: (epinephrine metabolic process) + +AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0192801023") Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving epinephrine, a hormone produced by the medulla of the adrenal glands that increases heart activity, improves the power and prolongs the action of muscles, and increases the rate and depth of breathing. It is synthesized by the methylation of norepinephrine.") +AnnotationAssertion( "adrenaline metabolic process") +AnnotationAssertion( "adrenaline metabolism") +AnnotationAssertion( "epinephrine metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042414") +AnnotationAssertion(rdfs:label "epinephrine metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (norepinephrine metabolic process) + +AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving norepinephrine, a hormone secreted by the adrenal medulla, and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts in the central nervous system. It is also the demethylated biosynthetic precursor of epinephrine.") +AnnotationAssertion( "levarterenol metabolic process") +AnnotationAssertion( "levarterenol metabolism") +AnnotationAssertion( "noradrenaline metabolic process") +AnnotationAssertion( "noradrenaline metabolism") +AnnotationAssertion( "norepinephrine metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042415") +AnnotationAssertion(rdfs:label "norepinephrine metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (dopamine biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline.") +AnnotationAssertion( "dopamine anabolism") +AnnotationAssertion( "dopamine biosynthesis") +AnnotationAssertion( "dopamine formation") +AnnotationAssertion( "dopamine synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042416") +AnnotationAssertion(rdfs:label "dopamine biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (dopamine metabolic process) + +AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline.") +AnnotationAssertion( "dopamine metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042417") +AnnotationAssertion(rdfs:label "dopamine metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (epinephrine biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0192801023") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of epinephrine, a hormone produced by the medulla of the adrenal glands that increases heart activity, improves the power and prolongs the action of muscles, and increases the rate and depth of breathing. It is synthesized by the methylation of norepinephrine.") +AnnotationAssertion( "adrenaline biosynthesis") +AnnotationAssertion( "adrenaline biosynthetic process") +AnnotationAssertion( "epinephrine anabolism") +AnnotationAssertion( "epinephrine biosynthesis") +AnnotationAssertion( "epinephrine formation") +AnnotationAssertion( "epinephrine synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042418") +AnnotationAssertion(rdfs:label "epinephrine biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (epinephrine catabolic process) + +AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0192801023") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of epinephrine, a hormone produced by the medulla of the adrenal glands that increases heart activity, improves the power and prolongs the action of muscles, and increases the rate and depth of breathing. It is synthesized by the methylation of norepinephrine.") +AnnotationAssertion( "adrenaline catabolic process") +AnnotationAssertion( "adrenaline catabolism") +AnnotationAssertion( "epinephrine breakdown") +AnnotationAssertion( "epinephrine catabolism") +AnnotationAssertion( "epinephrine degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042419") +AnnotationAssertion(rdfs:label "epinephrine catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (dopamine catabolic process) + +AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline.") +AnnotationAssertion( "dopamine breakdown") +AnnotationAssertion( "dopamine catabolism") +AnnotationAssertion( "dopamine degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042420") +AnnotationAssertion(rdfs:label "dopamine catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (norepinephrine biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of norepinephrine, a hormone secreted by the adrenal medulla, and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts in the central nervous system. It is also the demethylated biosynthetic precursor of epinephrine.") +AnnotationAssertion( "levarterenol biosynthesis") +AnnotationAssertion( "levarterenol biosynthetic process") +AnnotationAssertion( "noradrenaline biosynthesis") +AnnotationAssertion( "noradrenaline biosynthetic process") +AnnotationAssertion( "norepinephrine anabolism") +AnnotationAssertion( "norepinephrine biosynthesis") +AnnotationAssertion( "norepinephrine formation") +AnnotationAssertion( "norepinephrine synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042421") +AnnotationAssertion(rdfs:label "norepinephrine biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (norepinephrine catabolic process) + +AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of norepinephrine, a hormone secreted by the adrenal medulla, and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts in the central nervous system. It is also the demethylated biosynthetic precursor of epinephrine.") +AnnotationAssertion( "Wikipedia:Norepinephrine#Degradation") +AnnotationAssertion( "levarterenol catabolic process") +AnnotationAssertion( "levarterenol catabolism") +AnnotationAssertion( "noradrenaline catabolic process") +AnnotationAssertion( "noradrenaline catabolism") +AnnotationAssertion( "norepinephrine breakdown") +AnnotationAssertion( "norepinephrine catabolism") +AnnotationAssertion( "norepinephrine degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042422") +AnnotationAssertion(rdfs:label "norepinephrine catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (catecholamine biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine.") +AnnotationAssertion( "Wikipedia:Catecholamines") +AnnotationAssertion( "catecholamine anabolism") +AnnotationAssertion( "catecholamine biosynthesis") +AnnotationAssertion( "catecholamine formation") +AnnotationAssertion( "catecholamine synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042423") +AnnotationAssertion(rdfs:label "catecholamine biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (catecholamine catabolic process) + +AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine.") +AnnotationAssertion( "catecholamine breakdown") +AnnotationAssertion( "catecholamine catabolism") +AnnotationAssertion( "catecholamine degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042424") +AnnotationAssertion(rdfs:label "catecholamine catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (choline biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0192801023") "The chemical reactions and pathways resulting in the formation of choline (2-hydroxyethyltrimethylammonium), an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine.") +AnnotationAssertion( "MetaCyc:PWY-4762") +AnnotationAssertion( "choline anabolism") +AnnotationAssertion( "choline biosynthesis") +AnnotationAssertion( "choline formation") +AnnotationAssertion( "choline synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042425") +AnnotationAssertion(rdfs:label "choline biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (choline catabolic process) + +AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0192801023") "The chemical reactions and pathways resulting in the breakdown of choline (2-hydroxyethyltrimethylammonium), an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine.") +AnnotationAssertion( "choline breakdown") +AnnotationAssertion( "choline catabolism") +AnnotationAssertion( "choline degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042426") +AnnotationAssertion(rdfs:label "choline catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (serotonin biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties.") +AnnotationAssertion( "Wikipedia:Serotonin") +AnnotationAssertion( "serotonin anabolism") +AnnotationAssertion( "serotonin biosynthesis") +AnnotationAssertion( "serotonin formation") +AnnotationAssertion( "serotonin synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042427") +AnnotationAssertion(rdfs:label "serotonin biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (serotonin metabolic process) AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties.") @@ -35809,11 +80648,23 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0042428") AnnotationAssertion(rdfs:label "serotonin metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) +# Class: (serotonin catabolic process) + +AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties.") +AnnotationAssertion( "serotonin breakdown") +AnnotationAssertion( "serotonin catabolism") +AnnotationAssertion( "serotonin degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042429") +AnnotationAssertion(rdfs:label "serotonin catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (indole-containing compound metabolic process) AnnotationAssertion(Annotation( "GOC:jl") Annotation( "GOC:mah") "The chemical reactions and pathways involving compounds that contain an indole (2,3-benzopyrrole) skeleton.") @@ -35828,6 +80679,7 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0042430") AnnotationAssertion(rdfs:label "indole-containing compound metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ) @@ -35846,6 +80698,7 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0042435") AnnotationAssertion(rdfs:label "indole-containing compound biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ) @@ -35853,6 +80706,44 @@ SubClassOf( ) SubClassOf( ) +# Class: (indole-containing compound catabolic process) + +AnnotationAssertion(Annotation( "GOC:jl") "The chemical reactions and pathways resulting in the breakdown of compounds that contain an indole (2,3-benzopyrrole) skeleton.") +AnnotationAssertion( "indole derivative catabolic process") +AnnotationAssertion( "indole derivative catabolism") +AnnotationAssertion( "indole-containing compound breakdown") +AnnotationAssertion( "indole-containing compound catabolism") +AnnotationAssertion( "indole-containing compound degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042436") +AnnotationAssertion(rdfs:label "indole-containing compound catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (pigment metabolic process) + +AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving pigment, any general or particular coloring matter in living organisms, e.g. melanin.") +AnnotationAssertion( "pigment metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042440") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "pigment metabolic process") +SubClassOf( ) + +# Class: (melatonin catabolic process) + +AnnotationAssertion(Annotation( "GOC:jl") "The chemical reactions and pathways resulting in the breakdown of melatonin (N-acetyl-5-methoxytryptamine).") +AnnotationAssertion( "GO:0042449") +AnnotationAssertion( "melatonin breakdown") +AnnotationAssertion( "melatonin catabolism") +AnnotationAssertion( "melatonin degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042442") +AnnotationAssertion(rdfs:label "melatonin catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + # Class: (hormone metabolic process) AnnotationAssertion(Annotation( "GOC:jl") "The chemical reactions and pathways involving any hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone.") @@ -35882,6 +80773,146 @@ AnnotationAssertion( "hormone biosynthetic process") SubClassOf( ) +# Class: (hormone catabolic process) + +AnnotationAssertion(Annotation( "GOC:jl") "The chemical reactions and pathways resulting in the breakdown of any hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone.") +AnnotationAssertion( "hormone breakdown") +AnnotationAssertion( "hormone catabolism") +AnnotationAssertion( "hormone degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042447") +AnnotationAssertion(rdfs:label "hormone catabolic process") +SubClassOf( ) +SubClassOf( ) + +# Class: (progesterone metabolic process) + +AnnotationAssertion(Annotation( "GOC:jl") Annotation( "http://www.cogsci.princeton.edu/") "The chemical reactions and pathways involving progesterone, a steroid hormone produced in the ovary which prepares and maintains the uterus for pregnancy. Also found in plants.") +AnnotationAssertion( "progesterone metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042448") +AnnotationAssertion(rdfs:label "progesterone metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (purine nucleoside biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways resulting in the formation of any purine nucleoside, one of a family of organic molecules consisting of a purine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside).") +AnnotationAssertion( "purine nucleoside anabolism") +AnnotationAssertion( "purine nucleoside biosynthesis") +AnnotationAssertion( "purine nucleoside formation") +AnnotationAssertion( "purine nucleoside synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042451") +AnnotationAssertion(rdfs:label "purine nucleoside biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (ribonucleoside catabolic process) + +AnnotationAssertion(Annotation( "GOC:jl") "The chemical reactions and pathways resulting in the breakdown of any ribonucleoside, a nucleoside in which purine or pyrimidine base is linked to a ribose (beta-D-ribofuranose) molecule.") +AnnotationAssertion( "ribonucleoside breakdown") +AnnotationAssertion( "ribonucleoside catabolism") +AnnotationAssertion( "ribonucleoside degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042454") +AnnotationAssertion(rdfs:label "ribonucleoside catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (ribonucleoside biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:jl") "The chemical reactions and pathways resulting in the formation of any ribonucleoside, a nucleoside in which purine or pyrimidine base is linked to a ribose (beta-D-ribofuranose) molecule.") +AnnotationAssertion( "ribonucleoside anabolism") +AnnotationAssertion( "ribonucleoside biosynthesis") +AnnotationAssertion( "ribonucleoside formation") +AnnotationAssertion( "ribonucleoside synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042455") +AnnotationAssertion(rdfs:label "ribonucleoside biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (photoreceptor cell development) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Development of a photoreceptor, a cell that responds to incident electromagnetic radiation, particularly visible light.") +AnnotationAssertion( "GO:0046531") +AnnotationAssertion( "photoreceptor morphogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042461") +AnnotationAssertion(rdfs:label "photoreceptor cell development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (eye photoreceptor cell development) + +AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0192800981") "Development of a photoreceptor, a sensory cell in the eye that reacts to the presence of light. They usually contain a pigment that undergoes a chemical change when light is absorbed, thus stimulating a nerve.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042462") +AnnotationAssertion(rdfs:label "eye photoreceptor cell development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (melanosome) + +AnnotationAssertion(Annotation( "GOC:jl") Annotation( "PMID:11584301") "A tissue-specific, membrane-bounded cytoplasmic organelle within which melanin pigments are synthesized and stored. Melanosomes are synthesized in melanocyte cells.") +AnnotationAssertion( ) +AnnotationAssertion(Annotation( "GOC:kmv") ) +AnnotationAssertion( "Wikipedia:Melanosome") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0042470") +AnnotationAssertion(rdfs:label "melanosome") +SubClassOf( ) +SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "GOC:kmv") ObjectComplementOf(ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) +SubClassOf(Annotation( "GOC:kmv") ObjectSomeValuesFrom( ObjectComplementOf())) +SubClassOf( ObjectAllValuesFrom( )) +DisjointClasses( ObjectSomeValuesFrom( )) +DisjointClasses(Annotation( "GOC:kmv") ObjectSomeValuesFrom( )) + +# Class: (ear morphogenesis) + +AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0192801023") "The process in which the anatomical structures of the ear are generated and organized. The ear is the sense organ in vertebrates that is specialized for the detection of sound, and the maintenance of balance. Includes the outer ear and middle ear, which collect and transmit sound waves; and the inner ear, which contains the organs of balance and (except in fish) hearing. Also includes the pinna, the visible part of the outer ear, present in some mammals.") +AnnotationAssertion( "hearing organ morphogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042471") +AnnotationAssertion(rdfs:label "ear morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (inner ear morphogenesis) + +AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0192801023") "The process in which the anatomical structures of the inner ear are generated and organized. The inner ear is the structure in vertebrates that contains the organs of balance and hearing. It consists of soft hollow sensory structures (the membranous labyrinth) containing fluid (endolymph) surrounded by fluid (perilymph) and encased in a bony cavity (the bony labyrinth). It consists of two chambers, the sacculus and utriculus, from which arise the cochlea and semicircular canals respectively.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042472") +AnnotationAssertion(rdfs:label "inner ear morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (outer ear morphogenesis) + +AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0192801023") "The process in which the anatomical structures of the outer ear are generated and organized. The outer ear is the part of the ear external to the tympanum (eardrum). It consists of a tube (the external auditory meatus) that directs sound waves on to the tympanum, and may also include the external pinna, which extends beyond the skull.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042473") +AnnotationAssertion(rdfs:label "outer ear morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (middle ear morphogenesis) + +AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0192801023") "The process in which the anatomical structures of the middle ear are generated and organized. The middle ear is the air-filled cavity within the skull of vertebrates that lies between the outer ear and the inner ear. It is linked to the pharynx (and therefore to outside air) via the Eustachian tube and in mammals contains the three ear ossicles, which transmit auditory vibrations from the outer ear (via the tympanum) to the inner ear (via the oval window).") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042474") +AnnotationAssertion(rdfs:label "middle ear morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (odontogenesis of dentin-containing tooth) AnnotationAssertion(Annotation( "GOC:cjm") Annotation( "GOC:mah") Annotation( "GOC:mtg_sensu") Annotation( "PMID:10333884") Annotation( "PMID:15355794") "The process whose specific outcome is the progression of a dentin-containing tooth over time, from its formation to the mature structure. A dentin-containing tooth is a hard, bony organ borne on the jaw or other bone of a vertebrate, and is composed mainly of dentin, a dense calcified substance, covered by a layer of enamel.") @@ -35894,6 +80925,7 @@ AnnotationAssertion( "GO:0042475") AnnotationAssertion(rdfs:comment "Note that placoid scales found in the cartilaginous fishes presumably develop through the same processes, but are found on the dermis, rather than in the mouth or pharynx. See Wikipedia:Placoid_scale#Placoid_scales.") AnnotationAssertion(rdfs:label "odontogenesis of dentin-containing tooth") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectAllValuesFrom( )) @@ -35912,11 +80944,217 @@ AnnotationAssertion( "tooth development") AnnotationAssertion( "GO:0042476") AnnotationAssertion(rdfs:label "odontogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) DisjointClasses( ObjectSomeValuesFrom( )) +# Class: (regulation of eye photoreceptor cell development) + +AnnotationAssertion(Annotation( "GOC:jl") "Any process that modulates the frequency, rate or extent of eye photoreceptor development.") +AnnotationAssertion( "regulation of eye photoreceptor development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042478") +AnnotationAssertion(rdfs:label "regulation of eye photoreceptor cell development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (positive regulation of eye photoreceptor cell development) + +AnnotationAssertion(Annotation( "GOC:jl") "Any process that activates or increases the frequency, rate or extent of eye photoreceptor development.") +AnnotationAssertion( "positive regulation of eye photoreceptor development") +AnnotationAssertion( "up regulation of eye photoreceptor cell development") +AnnotationAssertion( "up-regulation of eye photoreceptor cell development") +AnnotationAssertion( "upregulation of eye photoreceptor cell development") +AnnotationAssertion( "activation of eye photoreceptor cell development") +AnnotationAssertion( "stimulation of eye photoreceptor cell development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042479") +AnnotationAssertion(rdfs:label "positive regulation of eye photoreceptor cell development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (negative regulation of eye photoreceptor cell development) + +AnnotationAssertion(Annotation( "GOC:jl") "Any process that stops, prevents, or reduces the frequency, rate or extent of eye photoreceptor development.") +AnnotationAssertion( "down regulation of eye photoreceptor cell development") +AnnotationAssertion( "down-regulation of eye photoreceptor cell development") +AnnotationAssertion( "downregulation of eye photoreceptor cell development") +AnnotationAssertion( "negative regulation of eye photoreceptor development") +AnnotationAssertion( "inhibition of eye photoreceptor cell development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042480") +AnnotationAssertion(rdfs:label "negative regulation of eye photoreceptor cell development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of odontogenesis) + +AnnotationAssertion(Annotation( "GOC:jl") "Any process that modulates the frequency, rate or extent of the formation and development of a tooth or teeth.") +AnnotationAssertion( "GO:0042484") +AnnotationAssertion( "regulation of tooth development") +AnnotationAssertion( "regulation of odontogenesis of calcareous or chitinous tooth") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042481") +AnnotationAssertion(rdfs:label "regulation of odontogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of odontogenesis) + +AnnotationAssertion(Annotation( "GOC:jl") "Any process that activates or increases the frequency, rate or extent of the formation and development of a tooth or teeth.") +AnnotationAssertion( "GO:0042485") +AnnotationAssertion( "positive regulation of tooth development") +AnnotationAssertion( "up regulation of odontogenesis") +AnnotationAssertion( "up-regulation of odontogenesis") +AnnotationAssertion( "upregulation of odontogenesis") +AnnotationAssertion( "activation of odontogenesis") +AnnotationAssertion( "positive regulation of odontogenesis of calcareous or chitinous tooth") +AnnotationAssertion( "stimulation of odontogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042482") +AnnotationAssertion(rdfs:label "positive regulation of odontogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of odontogenesis) + +AnnotationAssertion(Annotation( "GOC:jl") "Any process that stops, prevents, or reduces the frequency, rate or extent of the formation and development of a tooth or teeth.") +AnnotationAssertion( "GO:0042486") +AnnotationAssertion( "down regulation of odontogenesis") +AnnotationAssertion( "down-regulation of odontogenesis") +AnnotationAssertion( "downregulation of odontogenesis") +AnnotationAssertion( "negative regulation of tooth development") +AnnotationAssertion( "inhibition of odontogenesis") +AnnotationAssertion( "negative regulation of odontogenesis of calcareous or chitinous tooth") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042483") +AnnotationAssertion(rdfs:label "negative regulation of odontogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of odontogenesis of dentin-containing tooth) + +AnnotationAssertion(Annotation( "GOC:jl") Annotation( "GOC:mtg_sensu") Annotation( "PMID:15355794") "Any process that modulates the frequency, rate or extent of the formation and development of teeth, the hard, bony appendages which are borne on the jaws, or on other bones in the walls of the mouth or pharynx of most vertebrates.") +AnnotationAssertion( "regulation of odontogenesis of dentine-containing teeth") +AnnotationAssertion(Annotation( "GOC:mah") "regulation of odontogenesis of dentine-containing tooth") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042487") +AnnotationAssertion(rdfs:label "regulation of odontogenesis of dentin-containing tooth") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of odontogenesis of dentin-containing tooth) + +AnnotationAssertion(Annotation( "GOC:jl") Annotation( "PMID:15355794") "Any process that activates or increases the frequency, rate or extent of the formation and development of teeth, the hard, bony appendages that are borne on the jaws, or on other bones in the walls of the mouth or pharynx of most vertebrates.") +AnnotationAssertion( "activation of odontogenesis") +AnnotationAssertion( "stimulation of odontogenesis") +AnnotationAssertion( "up regulation of odontogenesis") +AnnotationAssertion( "up-regulation of odontogenesis") +AnnotationAssertion( "upregulation of odontogenesis") +AnnotationAssertion( "positive regulation of odontogenesis of dentine-containing teeth") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "positive regulation of odontogenesis of dentine-containing tooth") +AnnotationAssertion( "GO:0042488") +AnnotationAssertion(rdfs:label "positive regulation of odontogenesis of dentin-containing tooth") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of odontogenesis of dentin-containing tooth) + +AnnotationAssertion(Annotation( "GOC:jl") Annotation( "GOC:mtg_sensu") Annotation( "PMID:15355794") "Any process that stops, prevents, or reduces the frequency, rate or extent of the formation and development of teeth, the hard, bony appendages which are borne on the jaws, or on other bones in the walls of the mouth or pharynx.") +AnnotationAssertion( "down regulation of odontogenesis") +AnnotationAssertion( "down-regulation of odontogenesis") +AnnotationAssertion( "downregulation of odontogenesis") +AnnotationAssertion( "inhibition of odontogenesis") +AnnotationAssertion( "negative regulation of odontogenesis") +AnnotationAssertion( "negative regulation of odontogenesis of dentine-containing teeth") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "negative regulation of odontogenesis of dentine-containing tooth") +AnnotationAssertion( "GO:0042489") +AnnotationAssertion(rdfs:label "negative regulation of odontogenesis of dentin-containing tooth") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (mechanoreceptor differentiation) + +AnnotationAssertion(Annotation( "CL:0000199") Annotation( "GOC:jl") "The process in which a relatively unspecialized cell acquires specialized features of a mechanoreceptor, a cell specialized to transduce mechanical stimuli and relay that information centrally in the nervous system.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042490") +AnnotationAssertion(rdfs:label "mechanoreceptor differentiation") +SubClassOf( ) + +# Class: (inner ear auditory receptor cell differentiation) + +AnnotationAssertion(Annotation( "CL:0000201") Annotation( "GOC:jl") "The process in which a relatively unspecialized inner cell acquires specialized features of an auditory hair cell.") +AnnotationAssertion( "auditory hair cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "auditory receptor cell differentiation") +AnnotationAssertion( "GO:0042491") +AnnotationAssertion(rdfs:comment "Note that this term refers to the mechanosensory hair cells of the inner ear.") +AnnotationAssertion(rdfs:label "inner ear auditory receptor cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (neuron maturation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:jl") "A developmental process, independent of morphogenetic (shape) change, that is required for a neuron to attain its fully functional state.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042551") +AnnotationAssertion(rdfs:label "neuron maturation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (myelination) + +AnnotationAssertion(Annotation( "GOC:dgh") Annotation( "GOC:mah") "The process in which myelin sheaths are formed and maintained around neurons. Oligodendrocytes in the brain and spinal cord and Schwann cells in the peripheral nervous system wrap axons with compact layers of their plasma membrane. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier.") +AnnotationAssertion( "Wikipedia:Myelin") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:cjm") Annotation( "HP:0003429") "myelinogenesis") +AnnotationAssertion( "GO:0042552") +AnnotationAssertion(rdfs:label "myelination") +SubClassOf( ) + +# Class: (hormone binding) + +AnnotationAssertion(Annotation( "GOC:jl") "Binding to an hormone, a naturally occurring substance secreted by specialized cells that affect the metabolism or behavior of cells possessing functional receptors for the hormone. Hormones may be produced by the same, or different, cell as express the receptor.") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0042562") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "hormone binding") +SubClassOf( ) + +# Class: (immunoglobulin complex, circulating) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") "An immunoglobulin complex that is secreted into extracellular space and found in mucosal areas or other tissues or circulating in the blood or lymph. In its canonical form, a circulating immunoglobulin complex is composed of two identical heavy chains and two identical light chains, held together by disulfide bonds. Some forms of are polymers of the basic structure and contain additional components such as J-chain and the secretory component.") +AnnotationAssertion( "Wikipedia:Antibody") +AnnotationAssertion(Annotation( "GOC:add") "antibody") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0042571") +AnnotationAssertion(rdfs:comment "Note that an immunoglobulin complex has the function of antigen binding if a suitable antigen is available.") +AnnotationAssertion(rdfs:label "immunoglobulin complex, circulating") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (azurophil granule) + +AnnotationAssertion(Annotation( "GOC:jl") Annotation( "PMID:17152095") "Primary lysosomal granule found in neutrophil granulocytes. Contains a wide range of hydrolytic enzymes and is released into the extracellular fluid.") +AnnotationAssertion( "primary granule") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0042582") +AnnotationAssertion(rdfs:label "azurophil granule") +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (germinal vesicle) + +AnnotationAssertion(Annotation( "GOC:jl") Annotation( "GOC:mtg_sensu") Annotation( "PMID:19019837") "The enlarged, fluid filled nucleus of a primary oocyte, the development of which is suspended in prophase I of the first meiotic division between embryohood and sexual maturity.") +AnnotationAssertion( "primary oocyte nucleus") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0042585") +AnnotationAssertion(rdfs:label "germinal vesicle") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + # Class: (zymogen granule) AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0198506732") "A membrane-bounded, cytoplasmic secretory granule found in enzyme-secreting cells and visible by light microscopy. Contain zymogen, an inactive enzyme precursor, often of a digestive enzyme.") @@ -35931,6 +81169,7 @@ AnnotationAssertion(Annotation( "cellular_component") AnnotationAssertion( "GO:0042589") AnnotationAssertion(rdfs:label "zymogen granule membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) @@ -35954,6 +81193,121 @@ AnnotationAssertion( "homeostatic process") SubClassOf( ) +# Class: (glucose homeostasis) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process involved in the maintenance of an internal steady state of glucose within an organism or cell.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042593") +AnnotationAssertion(rdfs:label "glucose homeostasis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (egg chorion) + +AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0721662544") "A protective, noncellular membrane that surrounds the eggs of various animals including insects and fish.") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0042600") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:comment "Note that this term does not refer to the extraembryonic membrane surrounding the embryo of amniote vertebrates as this is an anatomical structure and is therefore not covered by GO.") +AnnotationAssertion(rdfs:label "egg chorion") +SubClassOf( ) + +# Class: (MHC protein complex) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:jl") Annotation( "ISBN:0781735149") Annotation( "PMID:15928678") Annotation( "PMID:16153240") "A transmembrane protein complex composed of an MHC alpha chain and, in most cases, either an MHC class II beta chain or an invariant beta2-microglobin chain, and with or without a bound peptide, lipid, or polysaccharide antigen.") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0042611") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "MHC protein complex") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (MHC class II protein complex) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:jl") Annotation( "ISBN:0120781859") Annotation( "PMID:15928678") "A transmembrane protein complex composed of an MHC class II alpha and MHC class II beta chain, and with or without a bound peptide or polysaccharide antigen.") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0042613") +AnnotationAssertion(rdfs:label "MHC class II protein complex") +SubClassOf( ) + +# Class: (hair cycle) + +AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "PMID:12230507") "The cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair; one of the collection or mass of filaments growing from the skin of an animal, and forming a covering for a part of the head or for any part or the whole of the body.") +AnnotationAssertion( ) +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042633") +AnnotationAssertion(rdfs:label "hair cycle") +SubClassOf( ) +SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) +SubClassOf( ObjectAllValuesFrom( )) +DisjointClasses( ObjectSomeValuesFrom( )) + +# Class: (regulation of hair cycle) + +AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "PMID:12230507") "Any process that modulates the frequency, rate or extent of the cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042634") +AnnotationAssertion(rdfs:label "regulation of hair cycle") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of hair cycle) + +AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "PMID:12230507") "Any process that activates or increases the frequency, rate or extent of the cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair.") +AnnotationAssertion( "up regulation of hair cycle") +AnnotationAssertion( "up-regulation of hair cycle") +AnnotationAssertion( "upregulation of hair cycle") +AnnotationAssertion( "activation of hair cycle") +AnnotationAssertion( "stimulation of hair cycle") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042635") +AnnotationAssertion(rdfs:label "positive regulation of hair cycle") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of hair cycle) + +AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "PMID:12230507") "Any process that stops, prevents, or reduces the frequency, rate or extent of the cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair.") +AnnotationAssertion( "down regulation of hair cycle") +AnnotationAssertion( "down-regulation of hair cycle") +AnnotationAssertion( "downregulation of hair cycle") +AnnotationAssertion( "inhibition of hair cycle") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042636") +AnnotationAssertion(rdfs:label "negative regulation of hair cycle") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (actomyosin) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any complex of actin, myosin, and accessory proteins.") +AnnotationAssertion( "actomyosin complex") +AnnotationAssertion( "actomyosin structure") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0042641") +AnnotationAssertion(rdfs:label "actomyosin") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (retinal cone cell differentiation) + +AnnotationAssertion(Annotation( "GOC:go_curators") "The process in which a relatively unspecialized cell acquires the specialized features of a retinal cone cell.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042670") +AnnotationAssertion(rdfs:label "retinal cone cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (muscle cell differentiation) + +AnnotationAssertion(Annotation( "CL:0000187") Annotation( "GOC:go_curators") "The process in which a relatively unspecialized cell acquires specialized features of a muscle cell.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "myogenesis") +AnnotationAssertion( "GO:0042692") +AnnotationAssertion(rdfs:label "muscle cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (ovulation cycle) AnnotationAssertion(Annotation( "ISBN:0721662544") "The type of sexual cycle seen in females, often with physiologic changes in the endometrium that recur at regular intervals during the reproductive years.") @@ -35972,11 +81326,22 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:0042701") AnnotationAssertion(rdfs:label "progesterone secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (uterine wall growth) + +AnnotationAssertion(Annotation( "GOC:jl") "The regrowth of the endometrium and blood vessels in the uterus following menstruation, resulting from a rise in progesterone levels.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042702") +AnnotationAssertion(rdfs:label "uterine wall growth") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (sperm ejaculation) AnnotationAssertion(Annotation( "GOC:jl") Annotation( "http://www.cogsci.princeton.edu/~wn/") "The expulsion of seminal fluid, thick white fluid containing spermatozoa, from the male genital tract.") @@ -35987,12 +81352,47 @@ SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (defense response to bacterium) + +AnnotationAssertion(Annotation( "GOC:jl") "Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism.") +AnnotationAssertion( "GO:0009816") +AnnotationAssertion( "GO:0042830") +AnnotationAssertion( "defence response to bacteria") +AnnotationAssertion( "defence response to bacterium") +AnnotationAssertion( "defense response to bacteria") +AnnotationAssertion( "defense response to bacterium, incompatible interaction") +AnnotationAssertion( "resistance response to pathogenic bacteria") +AnnotationAssertion( "resistance response to pathogenic bacterium") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "antibacterial peptide activity") +AnnotationAssertion( "GO:0042742") +AnnotationAssertion(rdfs:label "defense response to bacterium") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (circadian sleep/wake cycle) + +AnnotationAssertion(Annotation( "GOC:jl") Annotation( "http://www.sleepquest.com") "The cycle from wakefulness through an orderly succession of sleep states and stages that occurs on an approximately 24 hour rhythm.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042745") +AnnotationAssertion(rdfs:label "circadian sleep/wake cycle") +SubClassOf( ) + +# Class: (circadian sleep/wake cycle, non-REM sleep) + +AnnotationAssertion(Annotation( "GOC:jl") Annotation( "http://www.sleepquest.com") "All sleep stages in the circadian sleep/wake cycle other than REM sleep. These stages are characterized by a slowing of brain waves and other physiological functions.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042748") +AnnotationAssertion(rdfs:label "circadian sleep/wake cycle, non-REM sleep") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (regulation of circadian sleep/wake cycle) AnnotationAssertion(Annotation( "GOC:jl") "Any process that modulates the frequency, rate or extent of the circadian sleep/wake cycle.") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0042749") AnnotationAssertion(rdfs:label "regulation of circadian sleep/wake cycle") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ) @@ -36003,8 +81403,49 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:0042752") AnnotationAssertion(rdfs:label "regulation of circadian rhythm") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (positive regulation of circadian rhythm) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of a circadian rhythm behavior.") +AnnotationAssertion( "up regulation of circadian rhythm") +AnnotationAssertion( "up-regulation of circadian rhythm") +AnnotationAssertion( "upregulation of circadian rhythm") +AnnotationAssertion( "activation of circadian rhythm") +AnnotationAssertion( "stimulation of circadian rhythm") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042753") +AnnotationAssertion(rdfs:label "positive regulation of circadian rhythm") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of circadian rhythm) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of a circadian rhythm behavior.") +AnnotationAssertion( "down regulation of circadian rhythm") +AnnotationAssertion( "down-regulation of circadian rhythm") +AnnotationAssertion( "downregulation of circadian rhythm") +AnnotationAssertion( "inhibition of circadian rhythm") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042754") +AnnotationAssertion(rdfs:label "negative regulation of circadian rhythm") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of sulfur metabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving sulfur, the nonmetallic element sulfur or compounds that contain sulfur.") +AnnotationAssertion( "regulation of sulfur metabolism") +AnnotationAssertion( "regulation of sulphur metabolic process") +AnnotationAssertion( "regulation of sulphur metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042762") +AnnotationAssertion(rdfs:label "regulation of sulfur metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (amide transport) AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0198506732") "The directed movement of an amide, any compound containing one, two, or three acyl groups attached to a nitrogen atom, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") @@ -36012,8 +81453,134 @@ AnnotationAssertion( "GO:0042886") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "amide transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (amide transmembrane transporter activity) + +AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0198506732") "Enables the transfer of an amide, any compound containing one, two, or three acyl groups attached to a nitrogen atom, from one side of a membrane to the other.") +AnnotationAssertion( "amine/amide/polyamine channel activity") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0042887") +AnnotationAssertion(rdfs:label "amide transmembrane transporter activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (glucocorticoid receptor signaling pathway) + +AnnotationAssertion(Annotation( "GOC:mah") "The series of molecular signals initiated by glucocorticoid binding to its receptor.") +AnnotationAssertion( "glucocorticoid receptor signalling pathway") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042921") +AnnotationAssertion(rdfs:label "glucocorticoid receptor signaling pathway") +SubClassOf( ) + +# Class: (neuropeptide binding) + +AnnotationAssertion(Annotation( "http://www.wormbook.org/chapters/www_neuropeptides/neuropeptides.html") "Interacting selectively and non-covalently and stoichiometrically with neuropeptides, peptides with direct synaptic effects (peptide neurotransmitters) or indirect modulatory effects on the nervous system (peptide neuromodulators).") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0042923") +AnnotationAssertion(rdfs:label "neuropeptide binding") +SubClassOf( ) + +# Class: (D-amino acid transport) + +AnnotationAssertion(Annotation( "GOC:jl") Annotation( "GOC:jsg") Annotation( "GOC:mah") "The directed movement of the D-enantiomer of an amino acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042940") +AnnotationAssertion(rdfs:label "D-amino acid transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (D-amino acid transmembrane transporter activity) + +AnnotationAssertion(Annotation( "GOC:jl") Annotation( "GOC:jsg") Annotation( "GOC:mah") Annotation( "GOC:mtg_transport") Annotation( "ISBN:0815340729") "Enables the transfer of D-amino acids from one side of a membrane to the other. D-amino acids are the D-enantiomers of amino acids.") +AnnotationAssertion( "D-amino acid transporter activity") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0042943") +AnnotationAssertion(rdfs:label "D-amino acid transmembrane transporter activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (lipoprotein transport) + +AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0198506732") "The directed movement of any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042953") +AnnotationAssertion(rdfs:label "lipoprotein transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of apoptotic process) + +AnnotationAssertion(Annotation( "GOC:jl") Annotation( "GOC:mtg_apoptosis") "Any process that modulates the occurrence or rate of cell death by apoptotic process.") +AnnotationAssertion( "regulation of apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "apoptosis regulator activity") +AnnotationAssertion( "GO:0042981") +AnnotationAssertion(rdfs:comment "This term should only be used when it is not possible to determine which phase or subtype of the apoptotic process is regulated by a gene product. Whenever detailed information is available, the more granular children terms should be used.") +AnnotationAssertion(rdfs:label "regulation of apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (cell projection) + +AnnotationAssertion(Annotation( "GOC:jl") Annotation( "http://www.cogsci.princeton.edu/~wn/") "A prolongation or process extending from a cell, e.g. a flagellum or axon.") +AnnotationAssertion( "cell process") +AnnotationAssertion( "cellular process") +AnnotationAssertion( "cellular projection") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0042995") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "cell projection") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (regulation of Golgi to plasma membrane protein transport) + +AnnotationAssertion(Annotation( "GOC:jl") "Any process that modulates the frequency, rate or extent of the transport of proteins from the Golgi to the plasma membrane.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042996") +AnnotationAssertion(rdfs:label "regulation of Golgi to plasma membrane protein transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of Golgi to plasma membrane protein transport) + +AnnotationAssertion(Annotation( "GOC:jl") "Any process that stops, prevents, or reduces the frequency, rate or extent of the transport of proteins from the Golgi to the plasma membrane.") +AnnotationAssertion( "down regulation of Golgi to plasma membrane protein transport") +AnnotationAssertion( "down-regulation of Golgi to plasma membrane protein transport") +AnnotationAssertion( "downregulation of Golgi to plasma membrane protein transport") +AnnotationAssertion( "inhibition of Golgi to plasma membrane protein transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042997") +AnnotationAssertion(rdfs:label "negative regulation of Golgi to plasma membrane protein transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (positive regulation of Golgi to plasma membrane protein transport) + +AnnotationAssertion(Annotation( "GOC:jl") "Any process that activates or increases the frequency, rate or extent of the transport of proteins from the Golgi to the plasma membrane.") +AnnotationAssertion( "up regulation of Golgi to plasma membrane protein transport") +AnnotationAssertion( "up-regulation of Golgi to plasma membrane protein transport") +AnnotationAssertion( "upregulation of Golgi to plasma membrane protein transport") +AnnotationAssertion( "activation of Golgi to plasma membrane protein transport") +AnnotationAssertion( "stimulation of Golgi to plasma membrane protein transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0042998") +AnnotationAssertion(rdfs:label "positive regulation of Golgi to plasma membrane protein transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (Golgi to plasma membrane protein transport) + +AnnotationAssertion(Annotation( "ISBN:0716731363") "The directed movement of proteins from the Golgi to the plasma membrane in transport vesicles that move from the trans-Golgi network to the plasma membrane.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0043001") +AnnotationAssertion(rdfs:label "Golgi to plasma membrane protein transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + # Class: (neuron projection) AnnotationAssertion(Annotation( "GOC:jl") Annotation( "http://www.cogsci.princeton.edu/~wn/") "A prolongation or process extending from a nerve cell, e.g. an axon or dendrite.") @@ -36028,6 +81595,7 @@ AnnotationAssertion(Annotation( "GO:0043005") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "neuron projection") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) @@ -36080,7 +81648,6 @@ AnnotationAssertion( ) AnnotationAssertion(rdfs:label "ribonucleoprotein complex binding") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) # Class: (ribosome binding) @@ -36105,10 +81672,82 @@ AnnotationAssertion( ) AnnotationAssertion(rdfs:comment "Note that 'cell body' and 'cell soma' are not used in the literature for cells that lack projections, nor for some cells (e.g. yeast with mating projections) that do have projections.") AnnotationAssertion(rdfs:label "neuronal cell body") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (T cell homeostasis) + +AnnotationAssertion(Annotation( "GOC:mgi_curators") Annotation( "ISBN:0781735149") "The process of regulating the proliferation and elimination of T cells such that the total number of T cells within a whole or part of an organism is stable over time in the absence of an outside stimulus.") +AnnotationAssertion( "T lymphocyte homeostasis") +AnnotationAssertion( "T-cell homeostasis") +AnnotationAssertion( "T-lymphocyte homeostasis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0043029") +AnnotationAssertion(rdfs:comment "Note that this term represents the return of T cell levels to stable numbers following an immune response as well as the proliferation and elimination of T cells required to maintain stable numbers in the absence of an outside stimulus.") +AnnotationAssertion(rdfs:label "T cell homeostasis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of macrophage activation) + +AnnotationAssertion(Annotation( "GOC:jl") "Any process that modulates the frequency or rate of macrophage activation.") +AnnotationAssertion( "regulation of macrophage polarization") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0043030") +AnnotationAssertion(rdfs:label "regulation of macrophage activation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of macrophage activation) + +AnnotationAssertion(Annotation( "GOC:jl") "Any process that stops, prevents, or reduces the frequency, rate or extent of macrophage activation.") +AnnotationAssertion( "down regulation of macrophage activation") +AnnotationAssertion( "down-regulation of macrophage activation") +AnnotationAssertion( "downregulation of macrophage activation") +AnnotationAssertion( "negative regulation of macrophage polarization") +AnnotationAssertion( "inhibition of macrophage activation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0043031") +AnnotationAssertion(rdfs:label "negative regulation of macrophage activation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of macrophage activation) + +AnnotationAssertion(Annotation( "GOC:jl") "Any process that stimulates, induces or increases the rate of macrophage activation.") +AnnotationAssertion( "positive regulation of macrophage polarization") +AnnotationAssertion( "up regulation of macrophage activation") +AnnotationAssertion( "up-regulation of macrophage activation") +AnnotationAssertion( "upregulation of macrophage activation") +AnnotationAssertion( "activation of macrophage activation") +AnnotationAssertion( "stimulation of macrophage activation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0043032") +AnnotationAssertion(rdfs:label "positive regulation of macrophage activation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (peptide biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:jl") "The chemical reactions and pathways resulting in the formation of peptides, compounds of 2 or more (but usually less than 100) amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another. This may include the translation of a precursor protein and its subsequent processing into a functional peptide.") +AnnotationAssertion( "peptide anabolism") +AnnotationAssertion( "peptide biosynthesis") +AnnotationAssertion( "peptide formation") +AnnotationAssertion( "peptide synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0043043") +AnnotationAssertion(rdfs:label "peptide biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (otic placode formation) + +AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "PMID:12668634") "The initial developmental process that will lead to the formation of the vertebrate inner ear. The otic placode forms as a thickening of the head ectoderm adjacent to the developing hindbrain.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0043049") +AnnotationAssertion(rdfs:label "otic placode formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (extracellular structure organization) AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:dph") Annotation( "GOC:jl") Annotation( "GOC:mah") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures in the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane, and also covers the host cell environment outside an intracellular parasite.") @@ -36119,6 +81758,81 @@ AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "extracellular structure organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of apoptotic process) + +AnnotationAssertion(Annotation( "GOC:jl") Annotation( "GOC:mtg_apoptosis") "Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process.") +AnnotationAssertion( "up regulation of apoptosis") +AnnotationAssertion( "up-regulation of apoptosis") +AnnotationAssertion( "upregulation of apoptosis") +AnnotationAssertion( "activation of apoptosis") +AnnotationAssertion( "positive regulation of apoptosis") +AnnotationAssertion( "stimulation of apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "pro-apoptosis") +AnnotationAssertion( "GO:0043065") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:comment "This term should only be used when it is not possible to determine which phase or subtype of the apoptotic process is positively regulated by a gene product. Whenever detailed information is available, the more granular children terms should be used.") +AnnotationAssertion(rdfs:label "positive regulation of apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of apoptotic process) + +AnnotationAssertion(Annotation( "GOC:jl") Annotation( "GOC:mtg_apoptosis") "Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.") +AnnotationAssertion( "GO:0006916") +AnnotationAssertion( "anti-apoptosis") +AnnotationAssertion( "down regulation of apoptosis") +AnnotationAssertion( "down-regulation of apoptosis") +AnnotationAssertion( "downregulation of apoptosis") +AnnotationAssertion( "inhibition of apoptosis") +AnnotationAssertion( "negative regulation of apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "apoptosis inhibitor activity") +AnnotationAssertion( "pro-survival") +AnnotationAssertion( "GO:0043066") +AnnotationAssertion(rdfs:comment "This term should only be used when it is not possible to determine which phase or subtype of the apoptotic process is negatively regulated by a gene product. Whenever detailed information is available, the more granular children terms should be used.") +AnnotationAssertion(rdfs:label "negative regulation of apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of programmed cell death) + +AnnotationAssertion(Annotation( "GOC:jl") "Any process that modulates the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes.") +AnnotationAssertion( "GO:0043070") +AnnotationAssertion( "regulation of non-apoptotic programmed cell death") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0043067") +AnnotationAssertion(rdfs:label "regulation of programmed cell death") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of programmed cell death) + +AnnotationAssertion(Annotation( "GOC:jl") "Any process that activates or increases the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes.") +AnnotationAssertion( "GO:0043071") +AnnotationAssertion( "up regulation of programmed cell death") +AnnotationAssertion( "up-regulation of programmed cell death") +AnnotationAssertion( "upregulation of programmed cell death") +AnnotationAssertion( "activation of programmed cell death") +AnnotationAssertion( "positive regulation of non-apoptotic programmed cell death") +AnnotationAssertion( "stimulation of programmed cell death") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0043068") +AnnotationAssertion(rdfs:label "positive regulation of programmed cell death") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of programmed cell death) + +AnnotationAssertion(Annotation( "GOC:jl") "Any process that stops, prevents, or reduces the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes.") +AnnotationAssertion( "GO:0043072") +AnnotationAssertion( "down regulation of programmed cell death") +AnnotationAssertion( "down-regulation of programmed cell death") +AnnotationAssertion( "downregulation of programmed cell death") +AnnotationAssertion( "inhibition of programmed cell death") +AnnotationAssertion( "negative regulation of non-apoptotic programmed cell death") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0043069") +AnnotationAssertion(rdfs:label "negative regulation of programmed cell death") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (germ cell nucleus) @@ -36127,6 +81841,7 @@ AnnotationAssertion( "cellular_component") AnnotationAssertion( "GO:0043073") AnnotationAssertion(rdfs:label "germ cell nucleus") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) # Class: (penile erection) @@ -36140,6 +81855,83 @@ SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (positive regulation of catalytic activity) + +AnnotationAssertion(Annotation( "GOC:ebc") Annotation( "GOC:jl") Annotation( "GOC:tb") Annotation( "GOC:vw") "Any process that activates or increases the activity of an enzyme.") +AnnotationAssertion( "GO:0048554") +AnnotationAssertion(Annotation( "GOC:tb") "positive regulation of enzyme activity") +AnnotationAssertion( "up regulation of enzyme activity") +AnnotationAssertion( "up-regulation of enzyme activity") +AnnotationAssertion( "upregulation of enzyme activity") +AnnotationAssertion( "activation of enzyme activity") +AnnotationAssertion( "activation of metalloenzyme activity") +AnnotationAssertion( "positive regulation of metalloenzyme activity") +AnnotationAssertion( "stimulation of enzyme activity") +AnnotationAssertion( "stimulation of metalloenzyme activity") +AnnotationAssertion( "up regulation of metalloenzyme activity") +AnnotationAssertion( "up-regulation of metalloenzyme activity") +AnnotationAssertion( "upregulation of metalloenzyme activity") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0043085") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "positive regulation of catalytic activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of catalytic activity) + +AnnotationAssertion(Annotation( "GOC:ebc") Annotation( "GOC:jl") Annotation( "GOC:tb") Annotation( "GOC:vw") "Any process that stops or reduces the activity of an enzyme.") +AnnotationAssertion( "GO:0048553") +AnnotationAssertion( "down regulation of enzyme activity") +AnnotationAssertion( "down-regulation of enzyme activity") +AnnotationAssertion( "down-regulation of metalloenzyme activity") +AnnotationAssertion( "downregulation of enzyme activity") +AnnotationAssertion(Annotation( "GOC:tb") "negative regulation of enzyme activity") +AnnotationAssertion( "down regulation of metalloenzyme activity") +AnnotationAssertion( "downregulation of metalloenzyme activity") +AnnotationAssertion( "inhibition of enzyme activity") +AnnotationAssertion( "inhibition of metalloenzyme activity") +AnnotationAssertion( "negative regulation of metalloenzyme activity") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0043086") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "negative regulation of catalytic activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of vascular permeability) + +AnnotationAssertion(Annotation( "GOC:jl") "Any process that modulates the extent to which blood vessels can be pervaded by fluid.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0043114") +AnnotationAssertion(rdfs:label "regulation of vascular permeability") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (negative regulation of vascular permeability) + +AnnotationAssertion(Annotation( "GOC:jl") "Any process that reduces the extent to which blood vessels can be pervaded by fluid.") +AnnotationAssertion( "down regulation of vascular permeability") +AnnotationAssertion( "down-regulation of vascular permeability") +AnnotationAssertion( "downregulation of vascular permeability") +AnnotationAssertion( "inhibition of vascular permeability") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0043116") +AnnotationAssertion(rdfs:label "negative regulation of vascular permeability") +SubClassOf( ) + +# Class: (positive regulation of vascular permeability) + +AnnotationAssertion(Annotation( "GOC:jl") "Any process that increases the extent to which blood vessels can be pervaded by fluid.") +AnnotationAssertion( "up regulation of vascular permeability") +AnnotationAssertion( "up-regulation of vascular permeability") +AnnotationAssertion( "upregulation of vascular permeability") +AnnotationAssertion( "activation of vascular permeability") +AnnotationAssertion( "stimulation of vascular permeability") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0043117") +AnnotationAssertion(rdfs:label "positive regulation of vascular permeability") +SubClassOf( ) + # Class: (surfactant homeostasis) AnnotationAssertion(Annotation( "PMID:23708874") Annotation( "PMID:9751757") "Any process involved in the maintenance of a steady-state level of a surface-active agent that maintains the surface tension of a liquid.") @@ -36153,6 +81945,68 @@ AnnotationAssertion( "surfactant homeostasis") SubClassOf( ) +# Class: (hindgut contraction) + +AnnotationAssertion(Annotation( "GOC:jl") Annotation( "GOC:mtg_muscle") Annotation( "UBERON:0001046") "A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the hindgut. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The hindgut is the posterior part of the alimentary canal, including the rectum, and the large intestine.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0043133") +AnnotationAssertion(rdfs:label "hindgut contraction") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of hindgut contraction) + +AnnotationAssertion(Annotation( "GOC:jl") Annotation( "UBERON:0001046") "Any process that modulates the frequency, rate or extent of muscle contraction of the hindgut, the posterior part of the alimentary canal, including the rectum, and the large intestine.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0043134") +AnnotationAssertion(rdfs:label "regulation of hindgut contraction") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of translation by machinery localization) + +AnnotationAssertion(Annotation( "GOC:jl") "Any process in which proteins and protein complexes involved in translation are transported to, or maintained in, a specific location.") +AnnotationAssertion( "establishment and maintenance of translational machinery localization") +AnnotationAssertion( "establishment and maintenance of translational protein localization") +AnnotationAssertion(Annotation( "GOC:mah") "regulation of translation by machinery localisation") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "translational machinery localization") +AnnotationAssertion( "translational protein localization") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0043143") +AnnotationAssertion(rdfs:label "regulation of translation by machinery localization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (ion binding) + +AnnotationAssertion(Annotation( "GOC:jl") "Binding to an ion, a charged atoms or groups of atoms.") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "atom binding") +AnnotationAssertion( "GO:0043167") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "ion binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (anion binding) + +AnnotationAssertion(Annotation( "GOC:jl") "Binding to an anion, a charged atom or group of atoms with a net negative charge.") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0043168") +AnnotationAssertion(rdfs:label "anion binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (cation binding) + +AnnotationAssertion(Annotation( "GOC:jl") "Binding to a cation, a charged atom or group of atoms with a net positive charge.") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0043169") +AnnotationAssertion(rdfs:label "cation binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (macromolecule metabolic process) AnnotationAssertion(Annotation( "GOC:mah") "The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.") @@ -36167,6 +82021,80 @@ AnnotationAssertion( "GO:0043170") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "macromolecule metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (peptide catabolic process) + +AnnotationAssertion(Annotation( "GOC:jl") "The chemical reactions and pathways resulting in the breakdown of peptides, compounds of 2 or more (but usually less than 100) amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another.") +AnnotationAssertion( "peptide breakdown") +AnnotationAssertion( "peptide catabolism") +AnnotationAssertion( "peptide degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0043171") +AnnotationAssertion(rdfs:label "peptide catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (amine binding) + +AnnotationAssertion(Annotation( "GOC:jl") "Binding to an amine, a weakly basic organic compound that contains an amino or a substituted amino group.") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0043176") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "amine binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (organic acid binding) + +AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0198506732") "Binding to an organic acid, any acidic compound containing carbon in covalent linkage.") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0043177") +AnnotationAssertion(rdfs:label "organic acid binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (alcohol binding) + +AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0198506732") "Binding to an alcohol, any of a class of alkyl compounds containing a hydroxyl group.") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0043178") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "alcohol binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (vascular endothelial growth factor receptor 2 binding) + +AnnotationAssertion(Annotation( "GOC:st") "Binding to a vascular endothelial growth factor receptor 2.") +AnnotationAssertion( "KDR binding") +AnnotationAssertion( "Flk-1 binding") +AnnotationAssertion( "VEGF receptor 2 binding") +AnnotationAssertion( "VEGFR 2 binding") +AnnotationAssertion( "kinase domain region binding") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0043184") +AnnotationAssertion(rdfs:label "vascular endothelial growth factor receptor 2 binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (sulfate binding) + +AnnotationAssertion(Annotation( "GOC:mlg") "Binding to sulfate, SO4(2-), a negatively charged small molecule.") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0043199") +AnnotationAssertion(rdfs:label "sulfate binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (response to amino acid) + +AnnotationAssertion(Annotation( "GOC:ef") Annotation( "GOC:mlg") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups.") +AnnotationAssertion( "GO:0010237") +AnnotationAssertion(Annotation( "GOC:dos") "response to amino acid stimulus") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0043200") +AnnotationAssertion(rdfs:label "response to amino acid") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) # Class: (response to external biotic stimulus) @@ -36177,6 +82105,14 @@ AnnotationAssertion(rdfs:label "resp SubClassOf( ) SubClassOf( ) +# Class: (glycosphingolipid binding) + +AnnotationAssertion(Annotation( "GOC:jl") "Binding to glycosphingolipid, a compound with residues of sphingoid and at least one monosaccharide.") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0043208") +AnnotationAssertion(rdfs:label "glycosphingolipid binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (myelin sheath) AnnotationAssertion(Annotation( "GOC:cjm") Annotation( "GOC:jl") Annotation( "NIF_Subcellular:sao593830697") Annotation( "Wikipedia:Myelin") "An electrically insulating fatty layer that surrounds the axons of many neurons. It is an outgrowth of glial cells: Schwann cells supply the myelin for peripheral neurons while oligodendrocytes supply it to those of the central nervous system.") @@ -36217,6 +82153,7 @@ AnnotationAssertion( "cellular_component") AnnotationAssertion( "GO:0043227") AnnotationAssertion(rdfs:label "membrane-bounded organelle") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) DisjointClasses( ) @@ -36226,8 +82163,8 @@ AnnotationAssertion(Annotation( "https://github.com/geneontology/go-ontology/issues/21881"^^xsd:anyURI) AnnotationAssertion( "NIF_Subcellular:sao1456184038") AnnotationAssertion( "non-membrane-enclosed organelle") -AnnotationAssertion( "biological condensate") AnnotationAssertion( "cellular_component") +AnnotationAssertion( "biological condensate") AnnotationAssertion( "GO:0043228") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "non-membrane-bounded organelle") @@ -36240,6 +82177,19 @@ AnnotationAssertion( "GO:0043229") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "intracellular organelle") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +DisjointClasses( ) + +# Class: (extracellular organelle) + +AnnotationAssertion(Annotation( "GOC:jl") Annotation( "PMID:9914479") "Organized structure of distinctive morphology and function, occurring outside the cell. Includes, for example, extracellular membrane vesicles (EMVs) and the cellulosomes of anaerobic bacteria and fungi.") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0043230") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "extracellular organelle") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) # Class: (intracellular membrane-bounded organelle) @@ -36249,6 +82199,7 @@ AnnotationAssertion( "GO:0043231") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "intracellular membrane-bounded organelle") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) # Class: (intracellular non-membrane-bounded organelle) @@ -36404,15 +82355,16 @@ AnnotationAssertion( "response to alkaloid") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -# Class: (pharyngeal muscle development) +# Class: (chordate pharyngeal muscle development) AnnotationAssertion(Annotation( "GOC:go_curators") "The process whose specific outcome is the progression of the pharyngeal muscle over time, from its formation to the mature structure. A pharyngeal muscle is any muscle that forms part of the pharynx.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/18285"^^xsd:anyURI) AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0043282") -AnnotationAssertion(rdfs:label "pharyngeal muscle development") +AnnotationAssertion(rdfs:label "chordate pharyngeal muscle development") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) # Class: (contractile fiber) @@ -36457,7 +82409,6 @@ AnnotationAssertion( "leukocyte degranulation") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) -SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectAllValuesFrom( )) @@ -36511,9 +82462,8 @@ AnnotationAssertion( "GO:0043312") AnnotationAssertion(rdfs:label "neutrophil degranulation") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) SubClassOf( ) -SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) # Class: (regulation of neutrophil degranulation) @@ -36757,16 +82707,326 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0043436") AnnotationAssertion(rdfs:label "oxoacid metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (cellular alkane metabolic process) + +AnnotationAssertion(Annotation( "GOC:jl") Annotation( "Wikipedia:Alkane") "The chemical reactions and pathways involving an alkane, any acyclic branched or unbranched hydrocarbon having the general formula CnH2n+2, as carried out by individual cells.") +AnnotationAssertion( "alkane metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0043446") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "cellular alkane metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (alkane biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:jl") Annotation( "Wikipedia:Alkane") "The chemical reactions and pathways resulting in the formation of an alkane, any acyclic branched or unbranched hydrocarbon having the general formula CnH2n+2.") +AnnotationAssertion( "alkane anabolism") +AnnotationAssertion( "alkane biosynthesis") +AnnotationAssertion( "alkane formation") +AnnotationAssertion( "alkane synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0043447") +AnnotationAssertion(rdfs:label "alkane biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (alkane catabolic process) + +AnnotationAssertion(Annotation( "GOC:jl") Annotation( "Wikipedia:Alkane") "The chemical reactions and pathways resulting in the breakdown of an alkane, any acyclic branched or unbranched hydrocarbon having the general formula CnH2n+2.") +AnnotationAssertion( "alkane breakdown") +AnnotationAssertion( "alkane catabolism") +AnnotationAssertion( "alkane degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0043448") +AnnotationAssertion(rdfs:label "alkane catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of secondary metabolic process) + +AnnotationAssertion(Annotation( "GOC:jl") "Any process that modulates the frequency, rate or extent of secondary metabolism, the chemical reactions and pathways involving compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon.") +AnnotationAssertion( "regulation of secondary metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0043455") +AnnotationAssertion(rdfs:label "regulation of secondary metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of fermentation) + +AnnotationAssertion(Annotation( "GOC:jl") "Any process that modulates the frequency, rate or extent of fermentation, the anaerobic enzymatic conversion of organic compounds, especially carbohydrates, to other compounds, especially to ethyl alcohol, resulting in energy in the form of adenosine triphosphate (ATP).") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0043465") +AnnotationAssertion(rdfs:label "regulation of fermentation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of generation of precursor metabolites and energy) + +AnnotationAssertion(Annotation( "GOC:jl") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of precursor metabolites, substances from which energy is derived, and the processes involved in the liberation of energy from these substances.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0043467") +AnnotationAssertion(rdfs:label "regulation of generation of precursor metabolites and energy") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of carbohydrate catabolic process) + +AnnotationAssertion(Annotation( "GOC:mlg") "Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of carbohydrates.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0043470") +AnnotationAssertion(rdfs:label "regulation of carbohydrate catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (pigmentation) + +AnnotationAssertion(Annotation( "GOC:jl") "The accumulation of pigment in an organism, tissue or cell, either by increased deposition or by increased number of cells.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0043473") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "pigmentation") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectAllValuesFrom( )) + +# Class: (pigment metabolic process involved in pigmentation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:jl") Annotation( "GOC:tb") "The chemical reactions and pathways involving a pigment, any general or particular coloring matter in living organisms, resulting in the deposition or aggregation of pigment in an organism, tissue or cell.") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "pigment metabolic process during pigmentation") +AnnotationAssertion( "pigment metabolism during pigmentation") +AnnotationAssertion( "GO:0043474") +AnnotationAssertion(rdfs:label "pigment metabolic process involved in pigmentation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (muscle adaptation) + +AnnotationAssertion(Annotation( "GOC:mtg_muscle") Annotation( "PMID:11181628") Annotation( "PMID:11449884") Annotation( "PMID:12605307") "A process in which muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "muscle plasticity") +AnnotationAssertion( "GO:0043500") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "muscle adaptation") +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (skeletal muscle adaptation) + +AnnotationAssertion(Annotation( "GOC:mtg_muscle") Annotation( "PMID:11181628") Annotation( "PMID:11449884") Annotation( "PMID:12605307") "Any process in which skeletal muscles change their phenotypic profiles in response to altered functional demands and a variety of signals.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "skeletal muscle plasticity") +AnnotationAssertion( "GO:0043501") +AnnotationAssertion(rdfs:label "skeletal muscle adaptation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of muscle adaptation) + +AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "GOC:mtg_muscle") "Any process that modulates the frequency, rate or extent of muscle adaptation.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "regulation of muscle plasticity") +AnnotationAssertion( "GO:0043502") +AnnotationAssertion(rdfs:label "regulation of muscle adaptation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of neuron apoptotic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "GOC:mtg_apoptosis") "Any process that modulates the occurrence or rate of cell death by apoptotic process in neurons.") +AnnotationAssertion( "regulation of apoptosis of neuronal cells") +AnnotationAssertion( "regulation of apoptosis of neurons") +AnnotationAssertion( "regulation of neuron programmed cell death") +AnnotationAssertion( "regulation of neuronal cell programmed cell death") +AnnotationAssertion( "regulation of programmed cell death of neuronal cells") +AnnotationAssertion( "regulation of programmed cell death, neurons") +AnnotationAssertion( "regulation of neuron apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0043523") +AnnotationAssertion(rdfs:label "regulation of neuron apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of neuron apoptotic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "GOC:mtg_apoptosis") "Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process in neurons.") +AnnotationAssertion( "down regulation of neuron apoptosis") +AnnotationAssertion( "down-regulation of neuron apoptosis") +AnnotationAssertion( "downregulation of neuron apoptosis") +AnnotationAssertion( "negative regulation of programmed cell death, neurons") +AnnotationAssertion( "inhibition of neuron apoptosis") +AnnotationAssertion( "negative regulation of neuron apoptosis") +AnnotationAssertion( "neuron survival") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0043524") +AnnotationAssertion(rdfs:label "negative regulation of neuron apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of neuron apoptotic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "GOC:mtg_apoptosis") "Any process that activates or increases the frequency, rate or extent of cell death of neurons by apoptotic process.") +AnnotationAssertion( "positive regulation of programmed cell death, neurons") +AnnotationAssertion( "up regulation of neuron apoptosis") +AnnotationAssertion( "up-regulation of neuron apoptosis") +AnnotationAssertion( "upregulation of neuron apoptosis") +AnnotationAssertion( "activation of neuron apoptosis") +AnnotationAssertion( "positive regulation of neuron apoptosis") +AnnotationAssertion( "stimulation of neuron apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0043525") +AnnotationAssertion(rdfs:label "positive regulation of neuron apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (ADP binding) + +AnnotationAssertion(Annotation( "GOC:jl") "Binding to ADP, adenosine 5'-diphosphate.") +AnnotationAssertion( "adenosine 5'-diphosphate binding") +AnnotationAssertion( "adenosine diphosphate binding") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0043531") +AnnotationAssertion(rdfs:label "ADP binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (blood vessel endothelial cell migration) + +AnnotationAssertion(Annotation( "PMID:11166264") "The orderly movement of an endothelial cell into the extracellular matrix in order to form new blood vessels during angiogenesis.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0043534") +AnnotationAssertion(rdfs:label "blood vessel endothelial cell migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of blood vessel endothelial cell migration) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of the migration of the endothelial cells of blood vessels.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0043535") +AnnotationAssertion(rdfs:label "regulation of blood vessel endothelial cell migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of blood vessel endothelial cell migration) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of the migration of the endothelial cells of blood vessels.") +AnnotationAssertion( "up regulation of blood vessel endothelial cell migration") +AnnotationAssertion( "up-regulation of blood vessel endothelial cell migration") +AnnotationAssertion( "upregulation of blood vessel endothelial cell migration") +AnnotationAssertion( "activation of blood vessel endothelial cell migration") +AnnotationAssertion( "stimulation of blood vessel endothelial cell migration") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0043536") +AnnotationAssertion(rdfs:label "positive regulation of blood vessel endothelial cell migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of blood vessel endothelial cell migration) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of the migration of the endothelial cells of blood vessels.") +AnnotationAssertion( "down regulation of blood vessel endothelial cell migration") +AnnotationAssertion( "down-regulation of blood vessel endothelial cell migration") +AnnotationAssertion( "downregulation of blood vessel endothelial cell migration") +AnnotationAssertion( "inhibition of blood vessel endothelial cell migration") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0043537") +AnnotationAssertion(rdfs:label "negative regulation of blood vessel endothelial cell migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (endothelial cell migration) + +AnnotationAssertion(Annotation( "GOC:go_curators") "The orderly movement of an endothelial cell into the extracellular matrix to form an endothelium.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0043542") +AnnotationAssertion(rdfs:label "endothelial cell migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of kinase activity) + +AnnotationAssertion(Annotation( "GOC:bf") "Any process that modulates the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0043549") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "regulation of kinase activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (insulin binding) + +AnnotationAssertion(Annotation( "ISBN:0198506732") "Binding to insulin, a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms.") +AnnotationAssertion( ) +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0043559") +AnnotationAssertion(rdfs:label "insulin binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses( ObjectSomeValuesFrom( )) + # Class: (regulation of respiratory gaseous exchange) AnnotationAssertion(Annotation( "GOC:jl") "Any process that modulates the frequency, rate or extent of the process of gaseous exchange between an organism and its environment.") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0043576") AnnotationAssertion(rdfs:label "regulation of respiratory gaseous exchange") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (ear development) + +AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0192801023") "The process whose specific outcome is the progression of the ear over time, from its formation to the mature structure. The ear is the sense organ in vertebrates that is specialized for the detection of sound, and the maintenance of balance. Includes the outer ear and middle ear, which collect and transmit sound waves; and the inner ear, which contains the organs of balance and (except in fish) hearing. Also includes the pinna, the visible part of the outer ear, present in some mammals.") +AnnotationAssertion( "hearing organ development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0043583") +AnnotationAssertion(rdfs:label "ear development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (nose development) + +AnnotationAssertion(Annotation( "GOC:jl") "The process whose specific outcome is the progression of the nose over time, from its formation to the mature structure. The nose is the specialized structure of the face that serves as the organ of the sense of smell and as part of the respiratory system. Includes the nasi externus (external nose) and cavitas nasi (nasal cavity).") +AnnotationAssertion( "nasus development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0043584") +AnnotationAssertion(rdfs:label "nose development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (nose morphogenesis) + +AnnotationAssertion(Annotation( "GOC:jl") "The process in which the anatomical structures of the nose are generated and organized. The nose is the specialized structure of the face that serves as the organ of the sense of smell and as part of the respiratory system. Includes the nasi externus (external nose) and cavitas nasi (nasal cavity).") +AnnotationAssertion( "nasus morphogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0043585") +AnnotationAssertion(rdfs:label "nose morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (tongue development) + +AnnotationAssertion(Annotation( "GOC:jl") Annotation( "UBERON:0001723") "The process whose specific outcome is the progression of the tongue over time, from its formation to the mature structure. The tongue is the movable, muscular organ on the floor of the mouth of most vertebrates, in many other mammals is the principal organ of taste, aids in the prehension of food, in swallowing, and in modifying the voice as in speech.") +AnnotationAssertion( "glossa development") +AnnotationAssertion( "lingua development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0043586") +AnnotationAssertion(rdfs:label "tongue development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (tongue morphogenesis) + +AnnotationAssertion(Annotation( "GOC:jl") Annotation( "UBERON:0001723") "The process in which the anatomical structures of the tongue are generated and organized. The tongue is the movable, muscular organ on the floor of the mouth of most vertebrates, in man other mammals is the principal organ of taste, aids in the prehension of food, in swallowing, and in modifying the voice as in speech.") +AnnotationAssertion( "lingua morphogenesis") +AnnotationAssertion( "glossa morphogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0043587") +AnnotationAssertion(rdfs:label "tongue morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (skin development) AnnotationAssertion(Annotation( "GOC:jl") Annotation( "UBERON:0002097") "The process whose specific outcome is the progression of the skin over time, from its formation to the mature structure. The skin is the external membranous integument of an animal. In vertebrates the skin generally consists of two layers, an outer nonsensitive and nonvascular epidermis (cuticle or skarfskin) composed of cells which are constantly growing and multiplying in the deeper, and being thrown off in the superficial layers, as well as an inner vascular dermis (cutis, corium or true skin) composed mostly of connective tissue.") @@ -36776,6 +83036,7 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0043588") AnnotationAssertion(rdfs:label "skin development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) @@ -36784,6 +83045,16 @@ SubClassOf( ObjectSomeValuesFrom( ObjectSomeValuesFrom( )) DisjointClasses( ObjectSomeValuesFrom( )) +# Class: (skin morphogenesis) + +AnnotationAssertion(Annotation( "GOC:jl") Annotation( "UBERON:0002097") "The process in which the anatomical structures of the skin are generated and organized. The skin is the external membranous integument of an animal. In vertebrates the skin generally consists of two layers, an outer nonsensitive and nonvascular epidermis (cuticle or skarfskin) composed of cells which are constantly growing and multiplying in the deeper, and being thrown off in the superficial layers, as well as an inner, sensitive and vascular dermis (cutis, corium or true skin) composed mostly of connective tissue.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0043589") +AnnotationAssertion(rdfs:label "skin morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (amide metabolic process) AnnotationAssertion(Annotation( "GOC:curators") "The chemical reactions and pathways involving an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group, as carried out by individual cells.") @@ -36793,6 +83064,7 @@ AnnotationAssertion( "GO:0043603") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "amide metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (amide biosynthetic process) @@ -36800,9 +83072,30 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:0043604") AnnotationAssertion(rdfs:label "amide biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) +# Class: (amide catabolic process) + +AnnotationAssertion(Annotation( "GOC:curators") "The chemical reactions and pathways resulting in the breakdown of an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group.") +AnnotationAssertion( "cellular amide catabolic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0043605") +AnnotationAssertion(rdfs:label "amide catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (astrocyte cell migration) + +AnnotationAssertion(Annotation( "CL:0000127") Annotation( "GOC:go_curators") "The orderly movement of an astrocyte, a class of large neuroglial (macroglial) cells in the central nervous system, the largest and most numerous neuroglial cells in the brain and spinal cord.") +AnnotationAssertion( "astrocyte migration") +AnnotationAssertion( "astrocytic glial cell migration") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0043615") +AnnotationAssertion(rdfs:label "astrocyte cell migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + # Class: (keratinocyte proliferation) AnnotationAssertion(Annotation( "CL:0000311") "The multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population. Keratinocytes are epidermal cells which synthesize keratin and undergo a characteristic change as they move upward from the basal layers of the epidermis to the cornified (horny) layer of the skin.") @@ -36810,6 +83103,7 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0043616") AnnotationAssertion(rdfs:label "keratinocyte proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) @@ -36824,8 +83118,36 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0043648") AnnotationAssertion(rdfs:label "dicarboxylic acid metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (dicarboxylic acid catabolic process) + +AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of dicarboxylic acids, any organic acid containing two carboxyl (-COOH) groups.") +AnnotationAssertion( "dicarboxylate catabolic process") +AnnotationAssertion( "dicarboxylate catabolism") +AnnotationAssertion( "dicarboxylic acid breakdown") +AnnotationAssertion( "dicarboxylic acid catabolism") +AnnotationAssertion( "dicarboxylic acid degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0043649") +AnnotationAssertion(rdfs:label "dicarboxylic acid catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (dicarboxylic acid biosynthetic process) + +AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of dicarboxylic acids, any organic acid containing two carboxyl (-COOH) groups.") +AnnotationAssertion( "dicarboxylate biosynthesis") +AnnotationAssertion( "dicarboxylate biosynthetic process") +AnnotationAssertion( "dicarboxylic acid anabolism") +AnnotationAssertion( "dicarboxylic acid biosynthesis") +AnnotationAssertion( "dicarboxylic acid formation") +AnnotationAssertion( "dicarboxylic acid synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0043650") +AnnotationAssertion(rdfs:label "dicarboxylic acid biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (detection of pheromone) AnnotationAssertion(Annotation( "GOC:mah") "The series of events in which a pheromone stimulus is received by a cell and converted into a molecular signal.") @@ -36848,8 +83170,8 @@ EquivalentClasses( ObjectIntersection # Class: (ossification involved in bone remodeling) AnnotationAssertion(Annotation( "GOC:mtg_mpo") Annotation( "GO_REF:0000034") "The formation or growth of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone, involved in response to injury or other physical, physiological or environmental stress stimuli.") +AnnotationAssertion( "ossification involved in bone remodelling") AnnotationAssertion( "biological_process") -AnnotationAssertion( "ossification involved in bone remodelling") AnnotationAssertion( "GO:0043932") AnnotationAssertion(rdfs:label "ossification involved in bone remodeling") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) @@ -36875,6 +83197,7 @@ AnnotationAssertion( "protein-containing complex subunit organization") AnnotationAssertion( "GO:0043933") AnnotationAssertion(rdfs:label "protein-containing complex organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (glucan metabolic process) @@ -36883,6 +83206,7 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0044042") AnnotationAssertion(rdfs:label "glucan metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (regulation of system process) @@ -36890,6 +83214,7 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:0044057") AnnotationAssertion(rdfs:label "regulation of system process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) # Class: (regulation of digestive system process) @@ -36898,8 +83223,39 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:0044058") AnnotationAssertion(rdfs:label "regulation of digestive system process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (regulation of endocrine process) + +AnnotationAssertion(Annotation( "GOC:jl") "Any process that modulates the frequency, rate or extent of an endocrine process, a process involving the secretion of or response to endocrine hormones. An endocrine hormone is a hormone released into the circulatory system.") +AnnotationAssertion( "regulation of endocrine system process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0044060") +AnnotationAssertion(rdfs:label "regulation of endocrine process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of excretion) + +AnnotationAssertion(Annotation( "GOC:jl") "Any process that modulates the frequency, rate, or extent of excretion, the elimination by an organism of the waste products that arise as a result of metabolic activity.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0044062") +AnnotationAssertion(rdfs:label "regulation of excretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of respiratory system process) + +AnnotationAssertion(Annotation( "GOC:jl") "Any process that modulates the frequency, rate or extent of a respiratory system process, an organ system process carried out by any of the organs or tissues of the respiratory system.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0044065") +AnnotationAssertion(rdfs:label "regulation of respiratory system process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + # Class: (cellular component biogenesis) AnnotationAssertion(Annotation( "GOC:jl") Annotation( "GOC:mah") "A process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component. Includes biosynthesis of constituent macromolecules, and those macromolecular modifications that are involved in synthesis or assembly of the cellular component.") @@ -36911,6 +83267,88 @@ AnnotationAssertion( "cellular component biogenesis") SubClassOf( ) +# Class: (regulation of cellular component biogenesis) + +AnnotationAssertion(Annotation( "GOC:jl") "Any process that modulates the frequency, rate or extent of cellular component biogenesis, a process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0044087") +AnnotationAssertion(rdfs:label "regulation of cellular component biogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of vacuole organization) + +AnnotationAssertion(Annotation( "GOC:jl") Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a vacuole.") +AnnotationAssertion(Annotation( "GOC:mah") "regulation of vacuole organisation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:mah") "regulation of vacuole biogenesis") +AnnotationAssertion( "GO:0044088") +AnnotationAssertion(rdfs:label "regulation of vacuole organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of cellular component biogenesis) + +AnnotationAssertion(Annotation( "GOC:jl") "Any process that activates or increases the frequency, rate or extent of cellular component biogenesis, a process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0044089") +AnnotationAssertion(rdfs:label "positive regulation of cellular component biogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of vacuole organization) + +AnnotationAssertion(Annotation( "GOC:jl") Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a vacuole.") +AnnotationAssertion(Annotation( "GOC:mah") "positive regulation of vacuole organisation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:mah") "positive regulation of vacuole biogenesis") +AnnotationAssertion( "GO:0044090") +AnnotationAssertion(rdfs:label "positive regulation of vacuole organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (membrane biogenesis) + +AnnotationAssertion(Annotation( "GOC:jl") "A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a membrane.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0044091") +AnnotationAssertion(rdfs:label "membrane biogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of molecular function) + +AnnotationAssertion(Annotation( "GO:jl") "Any process that stops or reduces the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding.") +AnnotationAssertion( "jl") +AnnotationAssertion( "2009-04-21T04:07:27Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0044092") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "negative regulation of molecular function") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (positive regulation of molecular function) + +AnnotationAssertion(Annotation( "GO:jl") "Any process that activates or increases the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding.") +AnnotationAssertion( "jl") +AnnotationAssertion( "2009-04-21T04:11:06Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0044093") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "positive regulation of molecular function") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (translation initiation ternary complex) + +AnnotationAssertion(Annotation( "GOC:jl") "A ribonucleoprotein complex that contains aminoacylated initiator methionine tRNA, GTP, and initiation factor 2 (either eIF2 in eukaryotes, or IF2 in prokaryotes). In prokaryotes, fMet-tRNA (initiator) is used rather than Met-tRNA (initiator).") +AnnotationAssertion( "jl") +AnnotationAssertion( "2009-10-22T02:38:55Z") +AnnotationAssertion( "translation initiation (ternary) complex") +AnnotationAssertion( "Met-tRNA/eIF2.GTP ternary complex") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0044207") +AnnotationAssertion(rdfs:label "translation initiation ternary complex") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (cellular metabolic process) AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways by which individual cells transform chemical substances.") @@ -36934,6 +83372,31 @@ AnnotationAssertion( "primary metabolic process") SubClassOf( ) +# Class: (cellular lipid catabolic process) + +AnnotationAssertion(Annotation( "GOC:jl") "The chemical reactions and pathways resulting in the breakdown of lipids, as carried out by individual cells.") +AnnotationAssertion( "cellular lipid breakdown") +AnnotationAssertion( "cellular lipid catabolism") +AnnotationAssertion( "cellular lipid degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0044242") +AnnotationAssertion(rdfs:label "cellular lipid catabolic process") +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (cellular catabolic process) + +AnnotationAssertion(Annotation( "GOC:jl") "The chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells.") +AnnotationAssertion( "cellular breakdown") +AnnotationAssertion( "cellular catabolism") +AnnotationAssertion( "cellular degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0044248") +AnnotationAssertion(rdfs:label "cellular catabolic process") +SubClassOf( ) +SubClassOf( ) + # Class: (cellular biosynthetic process) AnnotationAssertion(Annotation( "GOC:jl") "The chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.") @@ -36947,6 +83410,40 @@ AnnotationAssertion(rdfs:label "cell SubClassOf( ) SubClassOf( ) +# Class: (cellular lipid metabolic process) + +AnnotationAssertion(Annotation( "GOC:jl") "The chemical reactions and pathways involving lipids, as carried out by individual cells.") +AnnotationAssertion( "cellular lipid metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0044255") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "cellular lipid metabolic process") +SubClassOf( ) +SubClassOf( ) + +# Class: (intestinal lipid catabolic process) + +AnnotationAssertion(Annotation( "GOC:jl") Annotation( "http://www.emc.maricopa.edu/") "The chemical reactions and pathways resulting in the breakdown into fatty acids and monoglycerides of lipids in the small intestine. Lipids are broken down by lipases released by the pancreas.") +AnnotationAssertion( "intestinal lipid breakdown") +AnnotationAssertion( "intestinal lipid catabolism") +AnnotationAssertion( "intestinal lipid degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0044258") +AnnotationAssertion(rdfs:label "intestinal lipid catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (cellular nitrogen compound catabolic process) + +AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of organic and inorganic nitrogenous compounds.") +AnnotationAssertion( "nitrogen compound breakdown") +AnnotationAssertion( "nitrogen compound catabolism") +AnnotationAssertion( "nitrogen compound degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0044270") +AnnotationAssertion(rdfs:label "cellular nitrogen compound catabolic process") +SubClassOf( ) +SubClassOf( ) + # Class: (cellular nitrogen compound biosynthetic process) AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of organic and inorganic nitrogenous compounds.") @@ -36960,6 +83457,35 @@ AnnotationAssertion(rdfs:label "cell SubClassOf( ) SubClassOf( ) +# Class: (sulfur compound biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:jl") "The chemical reactions and pathways resulting in the formation of compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione.") +AnnotationAssertion( "sulfur compound anabolism") +AnnotationAssertion( "sulfur compound biosynthesis") +AnnotationAssertion( "sulfur compound formation") +AnnotationAssertion( "sulfur compound synthesis") +AnnotationAssertion( "sulfur biosynthesis") +AnnotationAssertion( "sulfur biosynthetic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0044272") +AnnotationAssertion(rdfs:label "sulfur compound biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (sulfur compound catabolic process) + +AnnotationAssertion(Annotation( "GOC:jl") "The chemical reactions and pathways resulting in the breakdown of compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione.") +AnnotationAssertion( "sulfur compound breakdown") +AnnotationAssertion( "sulfur compound catabolism") +AnnotationAssertion( "sulfur compound degradation") +AnnotationAssertion( "sulfur catabolic process") +AnnotationAssertion( "sulfur catabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0044273") +AnnotationAssertion(rdfs:label "sulfur compound catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + # Class: (small molecule metabolic process) AnnotationAssertion(Annotation( "GOC:curators") Annotation( "GOC:pde") Annotation( "GOC:vw") "The chemical reactions and pathways involving small molecules, any low molecular weight, monomeric, non-encoded molecule.") @@ -36975,6 +83501,19 @@ AnnotationAssertion(rdfs:comment "Sm AnnotationAssertion(rdfs:label "small molecule metabolic process") SubClassOf( ) +# Class: (small molecule catabolic process) + +AnnotationAssertion(Annotation( "GOC:curators") Annotation( "GOC:vw") "The chemical reactions and pathways resulting in the breakdown of small molecules, any low molecular weight, monomeric, non-encoded molecule.") +AnnotationAssertion( "jl") +AnnotationAssertion( "2010-01-26T12:06:10Z") +AnnotationAssertion( "small molecule catabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0044282") +AnnotationAssertion(rdfs:comment "Small molecules in GO include monosaccharides but exclude disaccharides and polysaccharides.") +AnnotationAssertion(rdfs:label "small molecule catabolic process") +SubClassOf( ) +SubClassOf( ) + # Class: (small molecule biosynthetic process) AnnotationAssertion(Annotation( "GOC:curators") Annotation( "GOC:pde") Annotation( "GOC:vw") "The chemical reactions and pathways resulting in the formation of small molecules, any low molecular weight, monomeric, non-encoded molecule.") @@ -37009,20 +83548,6 @@ SubClassOf( ObjectSomeValuesFrom( ObjectSomeValuesFrom( ObjectComplementOf())) DisjointClasses( ObjectSomeValuesFrom( )) -# Class: (dentate gyrus mossy fiber) - -AnnotationAssertion(Annotation( "NIF_Subcellular:nlx_subcell_20090601") Annotation( "PMID:17765709") "Distinctive, unmyelinated axons produced by dentate gyrus granule cells.") -AnnotationAssertion( "jl") -AnnotationAssertion( "2010-02-05T11:23:55Z") -AnnotationAssertion( "granule cell axon") -AnnotationAssertion( "NIF_Subcellular:nlx_subcell_20090601") -AnnotationAssertion( "dentate gyrus mossy fibre") -AnnotationAssertion( "cellular_component") -AnnotationAssertion( "GO:0044302") -AnnotationAssertion(rdfs:label "dentate gyrus mossy fiber") -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (type B pancreatic cell proliferation) AnnotationAssertion(Annotation( "GOC:jl") Annotation( "GOC:yaf") "The multiplication or reproduction of pancreatic B cells, resulting in the expansion of an pancreatic B cell population. Pancreatic B cell are cells of the pancreas that secrete insulin.") @@ -37079,6 +83604,57 @@ SubClassOf( ObjectComplementOf(Object SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) DisjointClasses( ObjectSomeValuesFrom( )) +# Class: (motile cilium assembly) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:cilia") Annotation( "GOC:krc") Annotation( "GO_REF:0000079") Annotation( "PMID:19776033") Annotation( "PMID:21129373") Annotation( "ZFIN:dsf") "The aggregation, arrangement and bonding together of a set of components to form a motile cilium.") +AnnotationAssertion( "krc") +AnnotationAssertion( "2015-02-06T17:23:23Z") +AnnotationAssertion( "GO:1903887") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "motile primary cilia assembly") +AnnotationAssertion(Annotation( "GOC:TermGenie") "motile primary cilia formation") +AnnotationAssertion( "motile primary cilium assembly") +AnnotationAssertion(Annotation( "GOC:TermGenie") "motile primary cilium formation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "nodal cilium assembly") +AnnotationAssertion(Annotation( "GOC:TermGenie") "nodal cilium formation") +AnnotationAssertion( "GO:0044458") +AnnotationAssertion(rdfs:label "motile cilium assembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (secondary metabolite biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:jl") "The chemical reactions and pathways resulting in the formation of secondary metabolites, the compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon.") +AnnotationAssertion( "jl") +AnnotationAssertion( "2012-03-29T01:55:18Z") +AnnotationAssertion( "secondary metabolite biosynthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0044550") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "secondary metabolite biosynthetic process") +SubClassOf( ) +SubClassOf( ) + +# Class: (dendritic cell proliferation) + +AnnotationAssertion(Annotation( "CL:0000451") Annotation( "PMID:18469816") "The expansion of a dendritic cell population by cell division. A dendritic cell is a cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation.") +AnnotationAssertion( "jl") +AnnotationAssertion( "2012-04-05T04:31:39Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0044565") +AnnotationAssertion(rdfs:label "dendritic cell proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (chondrocyte activation) + +AnnotationAssertion(Annotation( "CL:0000138") Annotation( "GOC:jl") "A change in the morphology or behavior of a chondrocyte resulting from exposure to an activating factor such as a cellular or soluble ligand. A chondrocyte is a polymorphic cell that forms cartilage.") +AnnotationAssertion( "jl") +AnnotationAssertion( "2012-04-05T04:45:38Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0044566") +AnnotationAssertion(rdfs:label "chondrocyte activation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + # Class: (multi-organism reproductive process) AnnotationAssertion(Annotation( "GOC:jl") "A biological process that directly contributes to the process of producing new individuals, involving another organism.") @@ -37101,6 +83677,33 @@ AnnotationAssertion( "multi-multicellular organism process") SubClassOf( ) +# Class: (protein transmembrane import into intracellular organelle) + +AnnotationAssertion(Annotation( "GOC:jl") "The directed movement of proteins into an intracellular organelle, across a membrane.") +AnnotationAssertion( "jl") +AnnotationAssertion( "2012-11-07T15:37:36Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0044743") +AnnotationAssertion(rdfs:label "protein transmembrane import into intracellular organelle") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (cilium organization) + +AnnotationAssertion(Annotation( "GOC:cilia") Annotation( "GOC:jl") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole.") +AnnotationAssertion( "jl") +AnnotationAssertion( "2013-03-27T15:09:58Z") +AnnotationAssertion( "microtubule-based flagellum organization") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0044782") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:comment "Note that we deem cilium and microtubule-based flagellum to be equivalent.") +AnnotationAssertion(rdfs:label "cilium organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectAllValuesFrom( )) + # Class: (biological phase) AnnotationAssertion(Annotation( "GOC:jl") "A distinct period or stage in a biological process or cycle.") @@ -37118,6 +83721,107 @@ DisjointClasses( ) DisjointClasses( ) +# Class: (lipoprotein localization) + +AnnotationAssertion(Annotation( "GOC:jl") "Any process in which a lipoprotein is transported to, or maintained in, a specific location.") +AnnotationAssertion( "jl") +AnnotationAssertion( "2014-11-25T16:27:06Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0044872") +AnnotationAssertion(rdfs:label "lipoprotein localization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (lipoprotein localization to membrane) + +AnnotationAssertion(Annotation( "GOC:jl") "A process in which a lipoprotein is transported to, or maintained in, a specific location in a membrane.") +AnnotationAssertion( "jl") +AnnotationAssertion( "2014-11-25T16:28:43Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0044873") +AnnotationAssertion(rdfs:label "lipoprotein localization to membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (lipoprotein localization to outer membrane) + +AnnotationAssertion(Annotation( "GOC:jl") "A process in which a lipoprotein is transported to, or maintained in, a specific location in an outer membrane.") +AnnotationAssertion( "jl") +AnnotationAssertion( "2014-11-25T16:30:30Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0044874") +AnnotationAssertion(rdfs:label "lipoprotein localization to outer membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (protein-containing complex binding) + +AnnotationAssertion(Annotation( "GOC:jl") "Binding to a macromolecular complex.") +AnnotationAssertion( "jl") +AnnotationAssertion( "2014-12-16T11:38:58Z") +AnnotationAssertion( "GO:0032403") +AnnotationAssertion( "protein complex binding") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "macromolecular complex binding") +AnnotationAssertion( "GO:0044877") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "protein-containing complex binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (chitosome) + +AnnotationAssertion(Annotation( "ISBN:0198506732") Annotation( "PMID:8970154") "An intracellular membrane-bounded particle found in fungi and containing chitin synthase; it synthesizes chitin microfibrils. Chitin synthase activity exists in chitosomes and they are proposed to act as a reservoir for regulated transport of chitin synthase enzymes to the division septum.") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0045009") +AnnotationAssertion(rdfs:label "chitosome") +SubClassOf( ) + +# Class: (plasma membrane fusion) + +AnnotationAssertion(Annotation( "GOC:elh") Annotation( "GOC:mtg_muscle") "The joining of the lipid bilayer membrane that surround a cell with that of another cell, producing a single cell.") +AnnotationAssertion( "GO:0006947") +AnnotationAssertion( "cell fusion") +AnnotationAssertion( "cell-cell fusion") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045026") +AnnotationAssertion(rdfs:label "plasma membrane fusion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (G protein-coupled purinergic nucleotide receptor activity) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "PMID:9755289") "Combining with a purine nucleotide and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.") +AnnotationAssertion( "G protein coupled purinergic nucleotide receptor activity") +AnnotationAssertion( "G-protein coupled purinergic nucleotide receptor activity") +AnnotationAssertion( "purinergic nucleotide receptor activity, G protein coupled") +AnnotationAssertion(Annotation( "GOC:bf") "purinergic nucleotide receptor activity, G-protein coupled") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "P2Y") +AnnotationAssertion(Annotation( "PMID:9755289") "P2Y receptor") +AnnotationAssertion( "GO:0045028") +AnnotationAssertion(rdfs:label "G protein-coupled purinergic nucleotide receptor activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (G protein-coupled ATP receptor activity) + +AnnotationAssertion(Annotation( "GOC:mah") "Combining with ATP and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.") +AnnotationAssertion( "ATP-activated nucleotide receptor activity") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "ATP-activated adenosine receptor activity") +AnnotationAssertion( "GO:0045031") +AnnotationAssertion(rdfs:label "G protein-coupled ATP receptor activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulated exocytosis) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "ISBN:0716731363") "A process of exocytosis in which soluble proteins and other substances are initially stored in secretory vesicles for later release. It is found mainly in cells that are specialized for secreting products such as hormones, neurotransmitters, or digestive enzymes rapidly on demand.") +AnnotationAssertion( "regulated secretory pathway") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045055") +AnnotationAssertion(rdfs:label "regulated exocytosis") +SubClassOf( ) + # Class: (T cell selection) AnnotationAssertion(Annotation( "ISBN:0781735149") Annotation( "PMID:12414722") "The process in which T cells that express T cell receptors that are restricted by self MHC protein complexes and tolerant to self antigens are selected for further maturation.") @@ -37142,6 +83846,44 @@ AnnotationAssertion( "keratin filament") SubClassOf( ) +# Class: (intermediate filament-based process) + +AnnotationAssertion(Annotation( "GOC:ai") "Any cellular process that depends upon or alters the intermediate filament cytoskeleton, that part of the cytoskeleton comprising intermediate filaments and their associated proteins.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045103") +AnnotationAssertion(rdfs:label "intermediate filament-based process") +SubClassOf( ) + +# Class: (intermediate filament cytoskeleton organization) + +AnnotationAssertion(Annotation( "GOC:ai") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising intermediate filaments and their associated proteins.") +AnnotationAssertion( "intermediate filament cytoskeleton organisation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:mah") "intermediate filament cytoskeleton organization and biogenesis") +AnnotationAssertion( "GO:0045104") +AnnotationAssertion(rdfs:label "intermediate filament cytoskeleton organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (intermediate filament organization) + +AnnotationAssertion(Annotation( "GOC:ai") "Control of the spatial distribution of intermediate filaments; includes organizing filaments into meshworks, bundles, or other structures, as by cross-linking.") +AnnotationAssertion( "intermediate filament organisation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045109") +AnnotationAssertion(rdfs:label "intermediate filament organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (intermediate filament bundle assembly) + +AnnotationAssertion(Annotation( "ISBN:0716731363") "The formation of the bundles of intermediate filaments. Intermediate filament-associated proteins (IFAPs) cross-link intermediate filaments with one another, forming a bundle or a network, and with other cell structures, including the plasma membrane. The organization of intermediate filaments and their supportive function in various cells types depends in large part on their linkage to other cell structures via IFAPs.") +AnnotationAssertion( "tonofilament assembly") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045110") +AnnotationAssertion(rdfs:label "intermediate filament bundle assembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (intermediate filament cytoskeleton) AnnotationAssertion(Annotation( "ISBN:0716731363") "Cytoskeletal structure made from intermediate filaments, typically organized in the cytosol as an extended system that stretches from the nuclear envelope to the plasma membrane. Some intermediate filaments run parallel to the cell surface, while others traverse the cytosol; together they form an internal framework that helps support the shape and resilience of the cell.") @@ -37150,6 +83892,43 @@ AnnotationAssertion( "intermediate filament cytoskeleton") SubClassOf( ) +# Class: (azole transmembrane transport) + +AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:3527307206") Annotation( "Wikipedia:Azole") "The directed movement of azoles, heterocyclic compounds found in many biologically important substances, across a lipid bilayer, across a membrane.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "azole transport") +AnnotationAssertion( "GO:0045117") +AnnotationAssertion(rdfs:label "azole transmembrane transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (pronucleus) + +AnnotationAssertion(Annotation( "ISBN:0198506732") "The nucleus of either the ovum or the spermatozoon following fertilization. Thus, in the fertilized ovum, there are two pronuclei, one originating from the ovum, the other from the spermatozoon that brought about fertilization; they approach each other, but do not fuse until just before the first cleavage, when each pronucleus loses its membrane to release its contents.") +AnnotationAssertion( "Wikipedia:Pronucleus") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0045120") +AnnotationAssertion(rdfs:label "pronucleus") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectAllValuesFrom( )) + +# Class: (regulation of bone resorption) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of bone tissue loss (resorption).") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045124") +AnnotationAssertion(rdfs:label "regulation of bone resorption") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (meiotic chromosome segregation) + +AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:mah") "The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets during M phase of the meiotic cell cycle.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045132") +AnnotationAssertion(rdfs:label "meiotic chromosome segregation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (development of primary sexual characteristics) AnnotationAssertion(Annotation( "GOC:ai") "The process whose specific outcome is the progression of the primary sexual characteristics over time, from their formation to the mature structures. The primary sexual characteristics are the testes in males and the ovaries in females and they develop in response to sex hormone secretion.") @@ -37160,6 +83939,43 @@ SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (meiotic sister chromatid segregation) + +AnnotationAssertion(Annotation( "GOC:ai") Annotation( "ISBN:0815316194") "The cell cycle process in which sister chromatids are organized and then physically separated and randomly apportioned to two sets during the second division of the meiotic cell cycle.") +AnnotationAssertion( "meiosis II, chromosome segregation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045144") +AnnotationAssertion(rdfs:label "meiotic sister chromatid segregation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (cell fate commitment) + +AnnotationAssertion(Annotation( "ISBN:0716731185") "The cellular developmental process by which a cell establishes the intrinsic character of a cell or tissue region irreversibly committing it to a particular fate.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/24390"^^xsd:anyURI) +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045165") +AnnotationAssertion(rdfs:comment "Note that this term was 'cell fate determination' but the term name was changed to better match its existing definition and the child term 'cell fate determination; GO:0001709' was also created.") +AnnotationAssertion(rdfs:label "cell fate commitment") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cell-cell signaling involved in cell fate commitment) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:go_curators") Annotation( "GOC:tb") "Signaling at long or short range between cells that results in the commitment of a cell to a certain fate.") +AnnotationAssertion( "cell fate commitment, cell-cell signaling") +AnnotationAssertion( "cell fate commitment, cell-cell signalling") +AnnotationAssertion( "cell-cell signaling during in cell fate commitment") +AnnotationAssertion( "cell-cell signaling resulting in cell fate commitment") +AnnotationAssertion( "cell-cell signalling during cell fate commitment") +AnnotationAssertion( "cell-cell signalling resulting in cell fate commitment") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "cell-cell signalling involved in cell fate specification") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045168") +AnnotationAssertion(rdfs:label "cell-cell signaling involved in cell fate commitment") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (establishment of protein localization) AnnotationAssertion(Annotation( "GOC:bf") "The directed movement of a protein to a specific location.") @@ -37169,8 +83985,22 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0045184") AnnotationAssertion(rdfs:label "establishment of protein localization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (maintenance of protein location) + +AnnotationAssertion(Annotation( "GOC:bf") "Any process in which a protein is maintained in a location and prevented from moving elsewhere. These include sequestration, stabilization to prevent transport elsewhere and the active retrieval of proteins that do move away.") +AnnotationAssertion( "active protein retrieval") +AnnotationAssertion( "protein retention") +AnnotationAssertion( "protein sequestering") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "maintenance of protein localization") +AnnotationAssertion( "GO:0045185") +AnnotationAssertion(rdfs:label "maintenance of protein location") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (regulation of circadian sleep/wake cycle, sleep) AnnotationAssertion(Annotation( "GOC:jl") Annotation( "ISBN:0192800981") "Any process that modulates the frequency, rate or extent of sleep; a readily reversible state of reduced awareness and metabolic activity that occurs periodically in many animals.") @@ -37178,6 +84008,7 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0045187") AnnotationAssertion(rdfs:label "regulation of circadian sleep/wake cycle, sleep") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) # Class: (regulation of circadian sleep/wake cycle, non-REM sleep) @@ -37187,8 +84018,61 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0045188") AnnotationAssertion(rdfs:label "regulation of circadian sleep/wake cycle, non-REM sleep") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (isotype switching) + +AnnotationAssertion(Annotation( "ISBN:0781735149") "The switching of activated B cells from IgM biosynthesis to biosynthesis of other isotypes of immunoglobulin, accomplished through a recombination process involving an intrachromosomal deletion involving switch regions that reside 5' of each constant region gene segment in the immunoglobulin heavy chain locus.") +AnnotationAssertion( "Wikipedia:Immunoglobulin_class_switching") +AnnotationAssertion( "class switch recombination") +AnnotationAssertion( "class switching") +AnnotationAssertion( "isotype switch recombination") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045190") +AnnotationAssertion(rdfs:comment "Note that IgM and IgD can be coexpressed by B cells via an alternate splicing mechanism, but true recombinational isotype switching to IgD has been demonstrated as well. Note that this term is best used to annotate gene products which are involved in the mechanism of DNA recombination used in isotype switching, like the B cell specific Swap70 factor in the mouse, rather than gene products which promote isotype switching such as cytokines or co-stimulatory molecules, which should instead be annotated to 'regulation of isotype switching ; GO:0045191'.") +AnnotationAssertion(rdfs:label "isotype switching") +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of isotype switching) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of isotype switching.") +AnnotationAssertion( "regulation of class switch recombination") +AnnotationAssertion( "regulation of class switching") +AnnotationAssertion( "regulation of isotype switch recombination") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045191") +AnnotationAssertion(rdfs:label "regulation of isotype switching") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (establishment or maintenance of neuroblast polarity) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:mah") Annotation( "GOC:mtg_sensu") Annotation( "PMID:19375318") Annotation( "PMID:20066083") "Any cellular process that results in the specification, formation or maintenance of the apicobasal polarity of a neuroblast cell, a progenitor of the central nervous system.") +AnnotationAssertion( "GO:0043339") +AnnotationAssertion( "GO:0043342") +AnnotationAssertion( "establishment and/or maintenance of neuroblast cell polarity") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045196") +AnnotationAssertion(rdfs:label "establishment or maintenance of neuroblast polarity") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (establishment of neuroblast polarity) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:mtg_sensu") "The specification and formation of the apicobasal polarity of a neuroblast cell, a progenitor of the central nervous system.") +AnnotationAssertion( "GO:0043340") +AnnotationAssertion( "GO:0043343") +AnnotationAssertion( "establishment of neuroblast cell polarity") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045200") +AnnotationAssertion(rdfs:label "establishment of neuroblast polarity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + # Class: (synapse) AnnotationAssertion(Annotation( "GOC:aruk") Annotation( "ISBN:0198506732") Annotation( "PMID:24619342") Annotation( "PMID:29383328") Annotation( "PMID:31998110") "The junction between an axon of one neuron and a dendrite of another neuron, a muscle fiber or a glial cell. As the axon approaches the synapse it enlarges into a specialized structure, the presynaptic terminal bouton, which contains mitochondria and synaptic vesicles. At the tip of the terminal bouton is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic terminal bouton secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane.") @@ -37210,6 +84094,134 @@ SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectAllValuesFrom( )) +# Class: (postsynaptic membrane) + +AnnotationAssertion(Annotation( "ISBN:0198506732") "A specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft). Neurotransmitters cross the synaptic cleft and transmit the signal to the postsynaptic membrane.") +AnnotationAssertion( "post-synaptic membrane") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0045211") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "postsynaptic membrane") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (sarcomere organization) + +AnnotationAssertion(Annotation( "GOC:bf") "The myofibril assembly process that results in the organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs.") +AnnotationAssertion( "GO:0006938") +AnnotationAssertion( "sarcomere alignment") +AnnotationAssertion( "sarcomere organisation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045214") +AnnotationAssertion(rdfs:label "sarcomere organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cell-cell junction organization) + +AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:dph") Annotation( "GOC:jl") Annotation( "GOC:mah") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cell-cell junction. A cell-cell junction is a specialized region of connection between two cells.") +AnnotationAssertion( "cell-cell junction assembly and maintenance") +AnnotationAssertion(Annotation( "GOC:mah") "cell-cell junction organisation") +AnnotationAssertion( "intercellular junction assembly and maintenance") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "cell-cell junction biogenesis") +AnnotationAssertion( "GO:0045216") +AnnotationAssertion(rdfs:label "cell-cell junction organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (CD4 biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of CD4, a CD marker that occurs on T-helper cells and is involved in MHC class II restricted interactions.") +AnnotationAssertion( "CD4 anabolism") +AnnotationAssertion( "CD4 biosynthesis") +AnnotationAssertion( "CD4 formation") +AnnotationAssertion( "CD4 synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045222") +AnnotationAssertion(rdfs:label "CD4 biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of CD4 production) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of CD4.") +AnnotationAssertion( "regulation of CD4 anabolism") +AnnotationAssertion( "regulation of CD4 biosynthesis") +AnnotationAssertion( "regulation of CD4 biosynthetic process") +AnnotationAssertion( "regulation of CD4 formation") +AnnotationAssertion( "regulation of CD4 synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045223") +AnnotationAssertion(rdfs:label "regulation of CD4 production") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of CD4 production) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of CD4.") +AnnotationAssertion( "positive regulation of CD4 anabolism") +AnnotationAssertion( "positive regulation of CD4 biosynthesis") +AnnotationAssertion( "positive regulation of CD4 biosynthetic process") +AnnotationAssertion( "positive regulation of CD4 formation") +AnnotationAssertion( "positive regulation of CD4 synthesis") +AnnotationAssertion( "up regulation of CD4 biosynthetic process") +AnnotationAssertion( "up-regulation of CD4 biosynthetic process") +AnnotationAssertion( "upregulation of CD4 biosynthetic process") +AnnotationAssertion( "activation of CD4 biosynthetic process") +AnnotationAssertion( "stimulation of CD4 biosynthetic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045224") +AnnotationAssertion(rdfs:label "positive regulation of CD4 production") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of CD4 production) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of CD4.") +AnnotationAssertion( "down regulation of CD4 biosynthetic process") +AnnotationAssertion( "down-regulation of CD4 biosynthetic process") +AnnotationAssertion( "downregulation of CD4 biosynthetic process") +AnnotationAssertion( "negative regulation of CD4 anabolism") +AnnotationAssertion( "negative regulation of CD4 biosynthesis") +AnnotationAssertion( "negative regulation of CD4 biosynthetic process") +AnnotationAssertion( "negative regulation of CD4 formation") +AnnotationAssertion( "negative regulation of CD4 synthesis") +AnnotationAssertion( "inhibition of CD4 biosynthetic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045225") +AnnotationAssertion(rdfs:label "negative regulation of CD4 production") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (external encapsulating structure organization) + +AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:dph") Annotation( "GOC:jl") Annotation( "GOC:mah") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of external structures that lie outside the plasma membrane and surround the entire cell.") +AnnotationAssertion( "external encapsulating structure organisation") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:jl") Annotation( "GOC:mah") "external encapsulating structure organization and biogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045229") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "external encapsulating structure organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (cadherin binding) + +AnnotationAssertion(Annotation( "GOC:bf") "Binding to cadherin, a type I membrane protein involved in cell adhesion.") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0045296") +AnnotationAssertion(rdfs:label "cadherin binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (otolith mineralization) + +AnnotationAssertion(Annotation( "GOC:dsf") Annotation( "PMID:15581873") "The precipitation of specific crystal forms of calcium carbonate with extracellular matrix proteins in the otolith organs of the vertebrate inner ear.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045299") +AnnotationAssertion(rdfs:label "otolith mineralization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (leukocyte activation) AnnotationAssertion(Annotation( "GOC:add") "A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor.") @@ -37219,6 +84231,7 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0045321") AnnotationAssertion(rdfs:label "leukocyte activation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) @@ -37230,8 +84243,2849 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:0045443") AnnotationAssertion(rdfs:label "juvenile hormone secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (fat cell differentiation) + +AnnotationAssertion(Annotation( "CL:0000136") Annotation( "GOC:go_curators") "The process in which a relatively unspecialized cell acquires specialized features of an adipocyte, an animal connective tissue cell specialized for the synthesis and storage of fat.") +AnnotationAssertion( "adipocyte cell differentiation") +AnnotationAssertion( "adipocyte differentiation") +AnnotationAssertion( "adipose cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "adipogenesis") +AnnotationAssertion( "GO:0045444") +AnnotationAssertion(rdfs:label "fat cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (myoblast differentiation) + +AnnotationAssertion(Annotation( "CL:0000056") Annotation( "GOC:go_curators") Annotation( "GOC:mtg_muscle") "The process in which a relatively unspecialized cell acquires specialized features of a myoblast. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into striated muscle fibers.") +AnnotationAssertion( "myoblast cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045445") +AnnotationAssertion(rdfs:label "myoblast differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (endothelial cell differentiation) + +AnnotationAssertion(Annotation( "CL:0000115") Annotation( "GOC:go_curators") "The process in which a mesodermal, bone marrow or neural crest cell acquires specialized features of an endothelial cell, a thin flattened cell. A layer of such cells lines the inside surfaces of body cavities, blood vessels, and lymph vessels, making up the endothelium.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045446") +AnnotationAssertion(rdfs:label "endothelial cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (bone resorption) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "PMID:10968780") "The process in which specialized cells known as osteoclasts degrade the organic and inorganic portions of bone, and endocytose and transport the degradation products.") +AnnotationAssertion( "Wikipedia:Bone_resorption") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045453") +AnnotationAssertion(rdfs:label "bone resorption") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (regulation of imaginal disc growth) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of the growth of the imaginal disc.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045570") +AnnotationAssertion(rdfs:label "regulation of imaginal disc growth") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of imaginal disc growth) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of imaginal disc growth.") +AnnotationAssertion( "down regulation of imaginal disc growth") +AnnotationAssertion( "down-regulation of imaginal disc growth") +AnnotationAssertion( "downregulation of imaginal disc growth") +AnnotationAssertion( "inhibition of imaginal disc growth") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045571") +AnnotationAssertion(rdfs:label "negative regulation of imaginal disc growth") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of imaginal disc growth) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of imaginal disc growth.") +AnnotationAssertion( "up regulation of imaginal disc growth") +AnnotationAssertion( "up-regulation of imaginal disc growth") +AnnotationAssertion( "upregulation of imaginal disc growth") +AnnotationAssertion( "activation of imaginal disc growth") +AnnotationAssertion( "stimulation of imaginal disc growth") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045572") +AnnotationAssertion(rdfs:label "positive regulation of imaginal disc growth") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of B cell differentiation) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of B cell differentiation.") +AnnotationAssertion( "regulation of B lymphocyte differentiation") +AnnotationAssertion( "regulation of B-cell differentiation") +AnnotationAssertion( "regulation of B-lymphocyte differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:add") "regulation of B cell development") +AnnotationAssertion( "GO:0045577") +AnnotationAssertion(rdfs:comment "Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.") +AnnotationAssertion(rdfs:label "regulation of B cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of B cell differentiation) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of B cell differentiation.") +AnnotationAssertion( "down regulation of B cell differentiation") +AnnotationAssertion( "down-regulation of B cell differentiation") +AnnotationAssertion( "downregulation of B cell differentiation") +AnnotationAssertion( "negative regulation of B lymphocyte differentiation") +AnnotationAssertion( "negative regulation of B-cell differentiation") +AnnotationAssertion( "negative regulation of B-lymphocyte differentiation") +AnnotationAssertion( "inhibition of B cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:add") "negative regulation of B cell development") +AnnotationAssertion( "GO:0045578") +AnnotationAssertion(rdfs:comment "Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.") +AnnotationAssertion(rdfs:label "negative regulation of B cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of B cell differentiation) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of B cell differentiation.") +AnnotationAssertion( "positive regulation of B lymphocyte differentiation") +AnnotationAssertion( "positive regulation of B-cell differentiation") +AnnotationAssertion( "positive regulation of B-lymphocyte differentiation") +AnnotationAssertion( "up regulation of B cell differentiation") +AnnotationAssertion( "up-regulation of B cell differentiation") +AnnotationAssertion( "upregulation of B cell differentiation") +AnnotationAssertion( "activation of B cell differentiation") +AnnotationAssertion( "stimulation of B cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:add") "positive regulation of B cell development") +AnnotationAssertion( "GO:0045579") +AnnotationAssertion(rdfs:comment "Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.") +AnnotationAssertion(rdfs:label "positive regulation of B cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of T cell differentiation) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of T cell differentiation.") +AnnotationAssertion( "regulation of T lymphocyte differentiation") +AnnotationAssertion( "regulation of T-cell differentiation") +AnnotationAssertion( "regulation of T-lymphocyte differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:add") "regulation of T cell development") +AnnotationAssertion( "GO:0045580") +AnnotationAssertion(rdfs:comment "Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.") +AnnotationAssertion(rdfs:label "regulation of T cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of T cell differentiation) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of T cell differentiation.") +AnnotationAssertion( "down regulation of T cell differentiation") +AnnotationAssertion( "down-regulation of T cell differentiation") +AnnotationAssertion( "downregulation of T cell differentiation") +AnnotationAssertion( "negative regulation of T lymphocyte differentiation") +AnnotationAssertion( "negative regulation of T-cell differentiation") +AnnotationAssertion( "negative regulation of T-lymphocyte differentiation") +AnnotationAssertion( "inhibition of T cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:add") "negative regulation of T cell development") +AnnotationAssertion( "GO:0045581") +AnnotationAssertion(rdfs:comment "Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.") +AnnotationAssertion(rdfs:label "negative regulation of T cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of T cell differentiation) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of T cell differentiation.") +AnnotationAssertion( "positive regulation of T lymphocyte differentiation") +AnnotationAssertion( "positive regulation of T-cell differentiation") +AnnotationAssertion( "positive regulation of T-lymphocyte differentiation") +AnnotationAssertion( "up regulation of T cell differentiation") +AnnotationAssertion( "up-regulation of T cell differentiation") +AnnotationAssertion( "upregulation of T cell differentiation") +AnnotationAssertion( "activation of T cell differentiation") +AnnotationAssertion( "stimulation of T cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:add") "positive regulation of T cell development") +AnnotationAssertion( "GO:0045582") +AnnotationAssertion(rdfs:comment "Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.") +AnnotationAssertion(rdfs:label "positive regulation of T cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of cell differentiation) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of cell differentiation, the process in which relatively unspecialized cells acquire specialized structural and functional features.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045595") +AnnotationAssertion(rdfs:label "regulation of cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of cell differentiation) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of cell differentiation.") +AnnotationAssertion( "down regulation of cell differentiation") +AnnotationAssertion( "down-regulation of cell differentiation") +AnnotationAssertion( "downregulation of cell differentiation") +AnnotationAssertion( "inhibition of cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045596") +AnnotationAssertion(rdfs:label "negative regulation of cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of cell differentiation) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of cell differentiation.") +AnnotationAssertion( "up regulation of cell differentiation") +AnnotationAssertion( "up-regulation of cell differentiation") +AnnotationAssertion( "upregulation of cell differentiation") +AnnotationAssertion( "activation of cell differentiation") +AnnotationAssertion( "stimulation of cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045597") +AnnotationAssertion(rdfs:label "positive regulation of cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of fat cell differentiation) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of adipocyte differentiation.") +AnnotationAssertion( "regulation of adipocyte cell differentiation") +AnnotationAssertion( "regulation of adipocyte differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045598") +AnnotationAssertion(rdfs:label "regulation of fat cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of fat cell differentiation) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of adipocyte differentiation.") +AnnotationAssertion( "down regulation of fat cell differentiation") +AnnotationAssertion( "down-regulation of fat cell differentiation") +AnnotationAssertion( "downregulation of fat cell differentiation") +AnnotationAssertion( "negative regulation of adipocyte cell differentiation") +AnnotationAssertion( "negative regulation of adipocyte differentiation") +AnnotationAssertion( "inhibition of fat cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045599") +AnnotationAssertion(rdfs:label "negative regulation of fat cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of fat cell differentiation) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of adipocyte differentiation.") +AnnotationAssertion( "positive regulation of adipocyte cell differentiation") +AnnotationAssertion( "positive regulation of adipocyte differentiation") +AnnotationAssertion( "up regulation of fat cell differentiation") +AnnotationAssertion( "up-regulation of fat cell differentiation") +AnnotationAssertion( "upregulation of fat cell differentiation") +AnnotationAssertion( "activation of fat cell differentiation") +AnnotationAssertion( "stimulation of fat cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045600") +AnnotationAssertion(rdfs:label "positive regulation of fat cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of endothelial cell differentiation) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of endothelial cell differentiation.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045601") +AnnotationAssertion(rdfs:label "regulation of endothelial cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of endothelial cell differentiation) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of endothelial cell differentiation.") +AnnotationAssertion( "down regulation of endothelial cell differentiation") +AnnotationAssertion( "down-regulation of endothelial cell differentiation") +AnnotationAssertion( "downregulation of endothelial cell differentiation") +AnnotationAssertion( "inhibition of endothelial cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045602") +AnnotationAssertion(rdfs:label "negative regulation of endothelial cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of endothelial cell differentiation) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of endothelial cell differentiation.") +AnnotationAssertion( "up regulation of endothelial cell differentiation") +AnnotationAssertion( "up-regulation of endothelial cell differentiation") +AnnotationAssertion( "upregulation of endothelial cell differentiation") +AnnotationAssertion( "activation of endothelial cell differentiation") +AnnotationAssertion( "stimulation of endothelial cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045603") +AnnotationAssertion(rdfs:label "positive regulation of endothelial cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of epidermal cell differentiation) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of epidermal cell differentiation.") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:kmv") Annotation( "GOC:rk") "regulation of hypodermal cell differentiation") +AnnotationAssertion( "GO:0045604") +AnnotationAssertion(rdfs:label "regulation of epidermal cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of epidermal cell differentiation) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of epidermal cell differentiation.") +AnnotationAssertion( "down regulation of epidermal cell differentiation") +AnnotationAssertion( "down-regulation of epidermal cell differentiation") +AnnotationAssertion( "downregulation of epidermal cell differentiation") +AnnotationAssertion( "inhibition of epidermal cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:kmv") Annotation( "GOC:rk") "negative regulation of hypodermal cell differentiation") +AnnotationAssertion( "GO:0045605") +AnnotationAssertion(rdfs:label "negative regulation of epidermal cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of epidermal cell differentiation) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of epidermal cell differentiation.") +AnnotationAssertion( "up regulation of epidermal cell differentiation") +AnnotationAssertion( "up-regulation of epidermal cell differentiation") +AnnotationAssertion( "upregulation of epidermal cell differentiation") +AnnotationAssertion( "activation of epidermal cell differentiation") +AnnotationAssertion( "stimulation of epidermal cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:kmv") Annotation( "GOC:rk") "positive regulation of hypodermal cell differentiation") +AnnotationAssertion( "GO:0045606") +AnnotationAssertion(rdfs:label "positive regulation of epidermal cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of inner ear auditory receptor cell differentiation) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of auditory hair cell differentiation.") +AnnotationAssertion( "regulation of auditory hair cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "regulation of auditory receptor cell differentiation") +AnnotationAssertion( "GO:0045607") +AnnotationAssertion(rdfs:label "regulation of inner ear auditory receptor cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of inner ear auditory receptor cell differentiation) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of auditory hair cell differentiation.") +AnnotationAssertion( "down regulation of auditory receptor cell differentiation") +AnnotationAssertion( "down-regulation of auditory receptor cell differentiation") +AnnotationAssertion( "downregulation of auditory receptor cell differentiation") +AnnotationAssertion( "negative regulation of auditory hair cell differentiation") +AnnotationAssertion( "inhibition of auditory receptor cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "negative regulation of auditory receptor cell differentiation") +AnnotationAssertion( "GO:0045608") +AnnotationAssertion(rdfs:label "negative regulation of inner ear auditory receptor cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of inner ear auditory receptor cell differentiation) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of auditory hair cell differentiation.") +AnnotationAssertion( "positive regulation of auditory hair cell differentiation") +AnnotationAssertion( "up regulation of auditory receptor cell differentiation") +AnnotationAssertion( "up-regulation of auditory receptor cell differentiation") +AnnotationAssertion( "upregulation of auditory receptor cell differentiation") +AnnotationAssertion( "activation of auditory receptor cell differentiation") +AnnotationAssertion( "stimulation of auditory receptor cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "positive regulation of auditory receptor cell differentiation") +AnnotationAssertion( "GO:0045609") +AnnotationAssertion(rdfs:label "positive regulation of inner ear auditory receptor cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of hemocyte differentiation) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of hemocyte differentiation.") +AnnotationAssertion( "regulation of arthropod blood cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045610") +AnnotationAssertion(rdfs:label "regulation of hemocyte differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (negative regulation of hemocyte differentiation) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of hemocyte differentiation.") +AnnotationAssertion( "down regulation of hemocyte differentiation") +AnnotationAssertion( "down-regulation of hemocyte differentiation") +AnnotationAssertion( "downregulation of hemocyte differentiation") +AnnotationAssertion( "negative regulation of arthropod blood cell differentiation") +AnnotationAssertion( "inhibition of hemocyte differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045611") +AnnotationAssertion(rdfs:label "negative regulation of hemocyte differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of hemocyte differentiation) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of hemocyte differentiation.") +AnnotationAssertion( "positive regulation of arthropod blood cell differentiation") +AnnotationAssertion( "up regulation of hemocyte differentiation") +AnnotationAssertion( "up-regulation of hemocyte differentiation") +AnnotationAssertion( "upregulation of hemocyte differentiation") +AnnotationAssertion( "activation of hemocyte differentiation") +AnnotationAssertion( "stimulation of hemocyte differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045612") +AnnotationAssertion(rdfs:label "positive regulation of hemocyte differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of keratinocyte differentiation) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of keratinocyte differentiation.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045616") +AnnotationAssertion(rdfs:label "regulation of keratinocyte differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (negative regulation of keratinocyte differentiation) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of keratinocyte differentiation.") +AnnotationAssertion( "down regulation of keratinocyte differentiation") +AnnotationAssertion( "down-regulation of keratinocyte differentiation") +AnnotationAssertion( "downregulation of keratinocyte differentiation") +AnnotationAssertion( "inhibition of keratinocyte differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045617") +AnnotationAssertion(rdfs:label "negative regulation of keratinocyte differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of keratinocyte differentiation) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of keratinocyte differentiation.") +AnnotationAssertion( "up regulation of keratinocyte differentiation") +AnnotationAssertion( "up-regulation of keratinocyte differentiation") +AnnotationAssertion( "upregulation of keratinocyte differentiation") +AnnotationAssertion( "activation of keratinocyte differentiation") +AnnotationAssertion( "stimulation of keratinocyte differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045618") +AnnotationAssertion(rdfs:label "positive regulation of keratinocyte differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of lymphocyte differentiation) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of lymphocyte differentiation.") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:add") "regulation of lymphocyte development") +AnnotationAssertion( "GO:0045619") +AnnotationAssertion(rdfs:comment "Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.") +AnnotationAssertion(rdfs:label "regulation of lymphocyte differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of lymphocyte differentiation) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte differentiation.") +AnnotationAssertion( "down regulation of lymphocyte differentiation") +AnnotationAssertion( "down-regulation of lymphocyte differentiation") +AnnotationAssertion( "downregulation of lymphocyte differentiation") +AnnotationAssertion( "inhibition of lymphocyte differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:add") "negative regulation of lymphocyte development") +AnnotationAssertion( "GO:0045620") +AnnotationAssertion(rdfs:comment "Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.") +AnnotationAssertion(rdfs:label "negative regulation of lymphocyte differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of lymphocyte differentiation) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of lymphocyte differentiation.") +AnnotationAssertion( "up regulation of lymphocyte differentiation") +AnnotationAssertion( "up-regulation of lymphocyte differentiation") +AnnotationAssertion( "upregulation of lymphocyte differentiation") +AnnotationAssertion( "activation of lymphocyte differentiation") +AnnotationAssertion( "stimulation of lymphocyte differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:add") "positive regulation of lymphocyte development") +AnnotationAssertion( "GO:0045621") +AnnotationAssertion(rdfs:comment "Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.") +AnnotationAssertion(rdfs:label "positive regulation of lymphocyte differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of mechanoreceptor differentiation) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of mechanoreceptor differentiation.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045631") +AnnotationAssertion(rdfs:label "regulation of mechanoreceptor differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of mechanoreceptor differentiation) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of mechanoreceptor differentiation.") +AnnotationAssertion( "down regulation of mechanoreceptor differentiation") +AnnotationAssertion( "down-regulation of mechanoreceptor differentiation") +AnnotationAssertion( "downregulation of mechanoreceptor differentiation") +AnnotationAssertion( "inhibition of mechanoreceptor differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045632") +AnnotationAssertion(rdfs:label "negative regulation of mechanoreceptor differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of mechanoreceptor differentiation) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of mechanoreceptor differentiation.") +AnnotationAssertion( "up regulation of mechanoreceptor differentiation") +AnnotationAssertion( "up-regulation of mechanoreceptor differentiation") +AnnotationAssertion( "upregulation of mechanoreceptor differentiation") +AnnotationAssertion( "activation of mechanoreceptor differentiation") +AnnotationAssertion( "stimulation of mechanoreceptor differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045633") +AnnotationAssertion(rdfs:label "positive regulation of mechanoreceptor differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of melanocyte differentiation) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of melanocyte differentiation.") +AnnotationAssertion( "regulation of melanophore differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045634") +AnnotationAssertion(rdfs:label "regulation of melanocyte differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of melanocyte differentiation) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of melanocyte differentiation.") +AnnotationAssertion( "down regulation of melanocyte differentiation") +AnnotationAssertion( "down-regulation of melanocyte differentiation") +AnnotationAssertion( "downregulation of melanocyte differentiation") +AnnotationAssertion( "negative regulation of melanophore differentiation") +AnnotationAssertion( "inhibition of melanocyte differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045635") +AnnotationAssertion(rdfs:label "negative regulation of melanocyte differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of melanocyte differentiation) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of melanocyte differentiation.") +AnnotationAssertion( "positive regulation of melanophore differentiation") +AnnotationAssertion( "up regulation of melanocyte differentiation") +AnnotationAssertion( "up-regulation of melanocyte differentiation") +AnnotationAssertion( "upregulation of melanocyte differentiation") +AnnotationAssertion( "activation of melanocyte differentiation") +AnnotationAssertion( "stimulation of melanocyte differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045636") +AnnotationAssertion(rdfs:label "positive regulation of melanocyte differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of myeloid cell differentiation) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of myeloid cell differentiation.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045637") +AnnotationAssertion(rdfs:label "regulation of myeloid cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (negative regulation of myeloid cell differentiation) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of myeloid cell differentiation.") +AnnotationAssertion( "down regulation of myeloid cell differentiation") +AnnotationAssertion( "down-regulation of myeloid cell differentiation") +AnnotationAssertion( "downregulation of myeloid cell differentiation") +AnnotationAssertion( "inhibition of myeloid cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045638") +AnnotationAssertion(rdfs:label "negative regulation of myeloid cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of myeloid cell differentiation) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of myeloid cell differentiation.") +AnnotationAssertion( "up regulation of myeloid cell differentiation") +AnnotationAssertion( "up-regulation of myeloid cell differentiation") +AnnotationAssertion( "upregulation of myeloid cell differentiation") +AnnotationAssertion( "activation of myeloid cell differentiation") +AnnotationAssertion( "stimulation of myeloid cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045639") +AnnotationAssertion(rdfs:label "positive regulation of myeloid cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of erythrocyte differentiation) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of erythrocyte differentiation.") +AnnotationAssertion(Annotation( "CL:0000232") "regulation of RBC differentiation") +AnnotationAssertion(Annotation( "CL:0000232") "regulation of red blood cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045646") +AnnotationAssertion(rdfs:label "regulation of erythrocyte differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of erythrocyte differentiation) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of erythrocyte differentiation.") +AnnotationAssertion( "down regulation of erythrocyte differentiation") +AnnotationAssertion( "down-regulation of erythrocyte differentiation") +AnnotationAssertion( "downregulation of erythrocyte differentiation") +AnnotationAssertion(Annotation( "CL:0000232") "negative regulation of RBC differentiation") +AnnotationAssertion(Annotation( "CL:0000232") "negative regulation of red blood cell differentiation") +AnnotationAssertion( "inhibition of erythrocyte differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045647") +AnnotationAssertion(rdfs:label "negative regulation of erythrocyte differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of erythrocyte differentiation) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of erythrocyte differentiation.") +AnnotationAssertion(Annotation( "CL:0000232") "positive regulation of RBC differentiation") +AnnotationAssertion(Annotation( "CL:0000232") "positive regulation of red blood cell differentiation") +AnnotationAssertion( "up regulation of erythrocyte differentiation") +AnnotationAssertion( "up-regulation of erythrocyte differentiation") +AnnotationAssertion( "upregulation of erythrocyte differentiation") +AnnotationAssertion( "activation of erythrocyte differentiation") +AnnotationAssertion( "stimulation of erythrocyte differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045648") +AnnotationAssertion(rdfs:label "positive regulation of erythrocyte differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of macrophage differentiation) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of macrophage differentiation.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045649") +AnnotationAssertion(rdfs:label "regulation of macrophage differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of macrophage differentiation) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of macrophage differentiation.") +AnnotationAssertion( "down regulation of macrophage differentiation") +AnnotationAssertion( "down-regulation of macrophage differentiation") +AnnotationAssertion( "downregulation of macrophage differentiation") +AnnotationAssertion( "inhibition of macrophage differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045650") +AnnotationAssertion(rdfs:label "negative regulation of macrophage differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of macrophage differentiation) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of macrophage differentiation.") +AnnotationAssertion( "up regulation of macrophage differentiation") +AnnotationAssertion( "up-regulation of macrophage differentiation") +AnnotationAssertion( "upregulation of macrophage differentiation") +AnnotationAssertion( "activation of macrophage differentiation") +AnnotationAssertion( "stimulation of macrophage differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045651") +AnnotationAssertion(rdfs:label "positive regulation of macrophage differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of megakaryocyte differentiation) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of megakaryocyte differentiation.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045652") +AnnotationAssertion(rdfs:label "regulation of megakaryocyte differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of megakaryocyte differentiation) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of megakaryocyte differentiation.") +AnnotationAssertion( "down regulation of megakaryocyte differentiation") +AnnotationAssertion( "down-regulation of megakaryocyte differentiation") +AnnotationAssertion( "downregulation of megakaryocyte differentiation") +AnnotationAssertion( "inhibition of megakaryocyte differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045653") +AnnotationAssertion(rdfs:label "negative regulation of megakaryocyte differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of megakaryocyte differentiation) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of megakaryocyte differentiation.") +AnnotationAssertion( "up regulation of megakaryocyte differentiation") +AnnotationAssertion( "up-regulation of megakaryocyte differentiation") +AnnotationAssertion( "upregulation of megakaryocyte differentiation") +AnnotationAssertion( "activation of megakaryocyte differentiation") +AnnotationAssertion( "stimulation of megakaryocyte differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045654") +AnnotationAssertion(rdfs:label "positive regulation of megakaryocyte differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of monocyte differentiation) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of monocyte differentiation.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045655") +AnnotationAssertion(rdfs:label "regulation of monocyte differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of monocyte differentiation) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of monocyte differentiation.") +AnnotationAssertion( "down regulation of monocyte differentiation") +AnnotationAssertion( "down-regulation of monocyte differentiation") +AnnotationAssertion( "downregulation of monocyte differentiation") +AnnotationAssertion( "inhibition of monocyte differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045656") +AnnotationAssertion(rdfs:label "negative regulation of monocyte differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of monocyte differentiation) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of monocyte differentiation.") +AnnotationAssertion( "up regulation of monocyte differentiation") +AnnotationAssertion( "up-regulation of monocyte differentiation") +AnnotationAssertion( "upregulation of monocyte differentiation") +AnnotationAssertion( "activation of monocyte differentiation") +AnnotationAssertion( "stimulation of monocyte differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045657") +AnnotationAssertion(rdfs:label "positive regulation of monocyte differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of neutrophil differentiation) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of neutrophil differentiation.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045658") +AnnotationAssertion(rdfs:label "regulation of neutrophil differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of neutrophil differentiation) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of neutrophil differentiation.") +AnnotationAssertion( "down regulation of neutrophil differentiation") +AnnotationAssertion( "down-regulation of neutrophil differentiation") +AnnotationAssertion( "downregulation of neutrophil differentiation") +AnnotationAssertion( "inhibition of neutrophil differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045659") +AnnotationAssertion(rdfs:label "negative regulation of neutrophil differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of neutrophil differentiation) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of neutrophil differentiation.") +AnnotationAssertion( "up regulation of neutrophil differentiation") +AnnotationAssertion( "up-regulation of neutrophil differentiation") +AnnotationAssertion( "upregulation of neutrophil differentiation") +AnnotationAssertion( "activation of neutrophil differentiation") +AnnotationAssertion( "stimulation of neutrophil differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045660") +AnnotationAssertion(rdfs:label "positive regulation of neutrophil differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of myoblast differentiation) + +AnnotationAssertion(Annotation( "CL:0000056") Annotation( "GOC:go_curators") Annotation( "GOC:mtg_muscle") "Any process that modulates the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045661") +AnnotationAssertion(rdfs:label "regulation of myoblast differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of myoblast differentiation) + +AnnotationAssertion(Annotation( "CL:0000056") Annotation( "GOC:go_curators") Annotation( "GOC:mtg_muscle") "Any process that stops, prevents, or reduces the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.") +AnnotationAssertion( "down regulation of myoblast differentiation") +AnnotationAssertion( "down-regulation of myoblast differentiation") +AnnotationAssertion( "downregulation of myoblast differentiation") +AnnotationAssertion( "inhibition of myoblast differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045662") +AnnotationAssertion(rdfs:label "negative regulation of myoblast differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of myoblast differentiation) + +AnnotationAssertion(Annotation( "CL:0000056") Annotation( "GOC:go_curators") Annotation( "GOC:mtg_muscle") "Any process that activates or increases the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.") +AnnotationAssertion( "up regulation of myoblast differentiation") +AnnotationAssertion( "up-regulation of myoblast differentiation") +AnnotationAssertion( "upregulation of myoblast differentiation") +AnnotationAssertion( "activation of myoblast differentiation") +AnnotationAssertion( "stimulation of myoblast differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045663") +AnnotationAssertion(rdfs:label "positive regulation of myoblast differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of neuron differentiation) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of neuron differentiation.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045664") +AnnotationAssertion(rdfs:label "regulation of neuron differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectAllValuesFrom( )) + +# Class: (negative regulation of neuron differentiation) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of neuron differentiation.") +AnnotationAssertion( "down regulation of neuron differentiation") +AnnotationAssertion( "down-regulation of neuron differentiation") +AnnotationAssertion( "downregulation of neuron differentiation") +AnnotationAssertion( "inhibition of neuron differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045665") +AnnotationAssertion(rdfs:label "negative regulation of neuron differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of neuron differentiation) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of neuron differentiation.") +AnnotationAssertion( "up regulation of neuron differentiation") +AnnotationAssertion( "up-regulation of neuron differentiation") +AnnotationAssertion( "upregulation of neuron differentiation") +AnnotationAssertion( "activation of neuron differentiation") +AnnotationAssertion( "stimulation of neuron differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045666") +AnnotationAssertion(rdfs:label "positive regulation of neuron differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of osteoblast differentiation) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of osteoblast differentiation.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045667") +AnnotationAssertion(rdfs:label "regulation of osteoblast differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of osteoblast differentiation) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of osteoblast differentiation.") +AnnotationAssertion( "down regulation of osteoblast differentiation") +AnnotationAssertion( "down-regulation of osteoblast differentiation") +AnnotationAssertion( "downregulation of osteoblast differentiation") +AnnotationAssertion( "inhibition of osteoblast differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045668") +AnnotationAssertion(rdfs:label "negative regulation of osteoblast differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of osteoblast differentiation) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of osteoblast differentiation.") +AnnotationAssertion( "up regulation of osteoblast differentiation") +AnnotationAssertion( "up-regulation of osteoblast differentiation") +AnnotationAssertion( "upregulation of osteoblast differentiation") +AnnotationAssertion( "activation of osteoblast differentiation") +AnnotationAssertion( "stimulation of osteoblast differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045669") +AnnotationAssertion(rdfs:label "positive regulation of osteoblast differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of osteoclast differentiation) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of osteoclast differentiation.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045670") +AnnotationAssertion(rdfs:label "regulation of osteoclast differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of osteoclast differentiation) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of osteoclast differentiation.") +AnnotationAssertion( "down regulation of osteoclast differentiation") +AnnotationAssertion( "down-regulation of osteoclast differentiation") +AnnotationAssertion( "downregulation of osteoclast differentiation") +AnnotationAssertion( "inhibition of osteoclast differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045671") +AnnotationAssertion(rdfs:label "negative regulation of osteoclast differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of osteoclast differentiation) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of osteoclast differentiation.") +AnnotationAssertion( "up regulation of osteoclast differentiation") +AnnotationAssertion( "up-regulation of osteoclast differentiation") +AnnotationAssertion( "upregulation of osteoclast differentiation") +AnnotationAssertion( "activation of osteoclast differentiation") +AnnotationAssertion( "stimulation of osteoclast differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045672") +AnnotationAssertion(rdfs:label "positive regulation of osteoclast differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of epidermis development) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of epidermis development.") +AnnotationAssertion( "regulation of epidermal development") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:kmv") Annotation( "GOC:rk") "regulation of hypodermis development") +AnnotationAssertion( "GO:0045682") +AnnotationAssertion(rdfs:label "regulation of epidermis development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (negative regulation of epidermis development) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of epidermis development.") +AnnotationAssertion( "down regulation of epidermis development") +AnnotationAssertion( "down-regulation of epidermis development") +AnnotationAssertion( "downregulation of epidermis development") +AnnotationAssertion( "negative regulation of epidermal development") +AnnotationAssertion( "inhibition of epidermis development") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:kmv") Annotation( "GOC:rk") "negative regulation of hypodermis development") +AnnotationAssertion( "GO:0045683") +AnnotationAssertion(rdfs:label "negative regulation of epidermis development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of epidermis development) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of epidermis development.") +AnnotationAssertion( "positive regulation of epidermal development") +AnnotationAssertion( "up regulation of epidermis development") +AnnotationAssertion( "up-regulation of epidermis development") +AnnotationAssertion( "upregulation of epidermis development") +AnnotationAssertion( "activation of epidermis development") +AnnotationAssertion( "stimulation of epidermis development") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:kmv") Annotation( "GOC:rk") "positive regulation of hypodermis development") +AnnotationAssertion( "GO:0045684") +AnnotationAssertion(rdfs:label "positive regulation of epidermis development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of glial cell differentiation) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of glia cell differentiation.") +AnnotationAssertion( "regulation of glia cell differentiation") +AnnotationAssertion( "regulation of neuroglia differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045685") +AnnotationAssertion(rdfs:label "regulation of glial cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of glial cell differentiation) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of glia cell differentiation.") +AnnotationAssertion( "down regulation of glial cell differentiation") +AnnotationAssertion( "down-regulation of glial cell differentiation") +AnnotationAssertion( "downregulation of glial cell differentiation") +AnnotationAssertion( "negative regulation of glia cell differentiation") +AnnotationAssertion( "negative regulation of neuroglia differentiation") +AnnotationAssertion( "inhibition of glial cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045686") +AnnotationAssertion(rdfs:label "negative regulation of glial cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (positive regulation of glial cell differentiation) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of glia cell differentiation.") +AnnotationAssertion( "positive regulation of glia cell differentiation") +AnnotationAssertion( "positive regulation of neuroglia differentiation") +AnnotationAssertion( "up regulation of glial cell differentiation") +AnnotationAssertion( "up-regulation of glial cell differentiation") +AnnotationAssertion( "upregulation of glial cell differentiation") +AnnotationAssertion( "activation of glial cell differentiation") +AnnotationAssertion( "stimulation of glial cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045687") +AnnotationAssertion(rdfs:label "positive regulation of glial cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of spermatid nuclear differentiation) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of spermatid nuclear differentiation.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045700") +AnnotationAssertion(rdfs:label "regulation of spermatid nuclear differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (negative regulation of spermatid nuclear differentiation) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of spermatid nuclear differentiation.") +AnnotationAssertion( "down regulation of spermatid nuclear differentiation") +AnnotationAssertion( "down-regulation of spermatid nuclear differentiation") +AnnotationAssertion( "downregulation of spermatid nuclear differentiation") +AnnotationAssertion( "inhibition of spermatid nuclear differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045701") +AnnotationAssertion(rdfs:label "negative regulation of spermatid nuclear differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (positive regulation of spermatid nuclear differentiation) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of spermatid nuclear differentiation.") +AnnotationAssertion( "up regulation of spermatid nuclear differentiation") +AnnotationAssertion( "up-regulation of spermatid nuclear differentiation") +AnnotationAssertion( "upregulation of spermatid nuclear differentiation") +AnnotationAssertion( "activation of spermatid nuclear differentiation") +AnnotationAssertion( "stimulation of spermatid nuclear differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045702") +AnnotationAssertion(rdfs:label "positive regulation of spermatid nuclear differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of fatty acid biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fatty acids.") +AnnotationAssertion( "down regulation of fatty acid biosynthetic process") +AnnotationAssertion( "down-regulation of fatty acid biosynthetic process") +AnnotationAssertion( "downregulation of fatty acid biosynthetic process") +AnnotationAssertion( "negative regulation of fatty acid anabolism") +AnnotationAssertion( "negative regulation of fatty acid biosynthesis") +AnnotationAssertion( "negative regulation of fatty acid formation") +AnnotationAssertion( "negative regulation of fatty acid synthesis") +AnnotationAssertion( "inhibition of fatty acid biosynthetic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045717") +AnnotationAssertion(rdfs:label "negative regulation of fatty acid biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of glycogen biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen.") +AnnotationAssertion( "down regulation of glycogen biosynthetic process") +AnnotationAssertion( "down-regulation of glycogen biosynthetic process") +AnnotationAssertion( "downregulation of glycogen biosynthetic process") +AnnotationAssertion( "negative regulation of glycogen anabolism") +AnnotationAssertion( "negative regulation of glycogen biosynthesis") +AnnotationAssertion( "negative regulation of glycogen formation") +AnnotationAssertion( "negative regulation of glycogen synthesis") +AnnotationAssertion( "inhibition of glycogen biosynthetic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045719") +AnnotationAssertion(rdfs:label "negative regulation of glycogen biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of gluconeogenesis) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of gluconeogenesis.") +AnnotationAssertion( "down regulation of gluconeogenesis") +AnnotationAssertion( "down-regulation of gluconeogenesis") +AnnotationAssertion( "downregulation of gluconeogenesis") +AnnotationAssertion( "inhibition of gluconeogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045721") +AnnotationAssertion(rdfs:label "negative regulation of gluconeogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of gluconeogenesis) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of gluconeogenesis.") +AnnotationAssertion( "up regulation of gluconeogenesis") +AnnotationAssertion( "up-regulation of gluconeogenesis") +AnnotationAssertion( "upregulation of gluconeogenesis") +AnnotationAssertion( "activation of gluconeogenesis") +AnnotationAssertion( "stimulation of gluconeogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045722") +AnnotationAssertion(rdfs:label "positive regulation of gluconeogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (positive regulation of fatty acid biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fatty acids.") +AnnotationAssertion( "positive regulation of fatty acid anabolism") +AnnotationAssertion( "positive regulation of fatty acid biosynthesis") +AnnotationAssertion( "positive regulation of fatty acid formation") +AnnotationAssertion( "positive regulation of fatty acid synthesis") +AnnotationAssertion( "up regulation of fatty acid biosynthetic process") +AnnotationAssertion( "up-regulation of fatty acid biosynthetic process") +AnnotationAssertion( "upregulation of fatty acid biosynthetic process") +AnnotationAssertion( "activation of fatty acid biosynthetic process") +AnnotationAssertion( "stimulation of fatty acid biosynthetic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045723") +AnnotationAssertion(rdfs:label "positive regulation of fatty acid biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of cilium assembly) + +AnnotationAssertion(Annotation( "GOC:cilia") Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of the formation of a cilium.") +AnnotationAssertion( "positive regulation of flagellum assembly") +AnnotationAssertion( "up regulation of cilium assembly") +AnnotationAssertion( "up-regulation of cilium assembly") +AnnotationAssertion( "upregulation of cilium assembly") +AnnotationAssertion( "activation of cilium assembly") +AnnotationAssertion( "stimulation of cilium assembly") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:mah") "positive regulation of flagellum biogenesis") +AnnotationAssertion( "GO:0045724") +AnnotationAssertion(rdfs:label "positive regulation of cilium assembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of glycogen biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen.") +AnnotationAssertion( "positive regulation of glycogen anabolism") +AnnotationAssertion( "positive regulation of glycogen biosynthesis") +AnnotationAssertion( "positive regulation of glycogen formation") +AnnotationAssertion( "positive regulation of glycogen synthesis") +AnnotationAssertion( "up regulation of glycogen biosynthetic process") +AnnotationAssertion( "up-regulation of glycogen biosynthetic process") +AnnotationAssertion( "upregulation of glycogen biosynthetic process") +AnnotationAssertion( "activation of glycogen biosynthetic process") +AnnotationAssertion( "stimulation of glycogen biosynthetic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045725") +AnnotationAssertion(rdfs:label "positive regulation of glycogen biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of translation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:go_curators") Annotation( "GOC:tb") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA.") +AnnotationAssertion( "GO:0045946") +AnnotationAssertion( "positive regulation of protein anabolism") +AnnotationAssertion( "positive regulation of protein biosynthesis") +AnnotationAssertion(Annotation( "GOC:tb") "positive regulation of protein biosynthetic process") +AnnotationAssertion( "positive regulation of protein formation") +AnnotationAssertion( "positive regulation of protein synthesis") +AnnotationAssertion( "up regulation of protein biosynthetic process") +AnnotationAssertion( "up-regulation of protein biosynthetic process") +AnnotationAssertion( "upregulation of protein biosynthetic process") +AnnotationAssertion( "activation of protein biosynthetic process") +AnnotationAssertion( "stimulation of protein biosynthetic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045727") +AnnotationAssertion(rdfs:label "positive regulation of translation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (positive regulation of protein catabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/23112"^^xsd:anyURI) +AnnotationAssertion( "GO:1903364") +AnnotationAssertion( "GO:2000600") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of cellular protein breakdown") +AnnotationAssertion( "positive regulation of cellular protein catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of cellular protein catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of cellular protein degradation") +AnnotationAssertion( "positive regulation of protein breakdown") +AnnotationAssertion( "positive regulation of protein catabolism") +AnnotationAssertion( "positive regulation of protein degradation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of cellular protein breakdown") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of cellular protein catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of cellular protein catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of cellular protein degradation") +AnnotationAssertion( "up regulation of protein catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of cellular protein breakdown") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of cellular protein catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of cellular protein catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of cellular protein degradation") +AnnotationAssertion( "up-regulation of protein catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of cellular protein breakdown") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of cellular protein catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of cellular protein catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of cellular protein degradation") +AnnotationAssertion( "upregulation of protein catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of cellular protein breakdown") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of cellular protein catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of cellular protein catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of cellular protein degradation") +AnnotationAssertion( "activation of protein catabolic process") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of cyclin breakdown") +AnnotationAssertion( "positive regulation of cyclin catabolic process") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of cyclin catabolism") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of cyclin degradation") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of degradation of cyclin") +AnnotationAssertion( "stimulation of protein catabolic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045732") +AnnotationAssertion(rdfs:label "positive regulation of protein catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (acetate catabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways resulting in the breakdown of acetate, the anion of acetic acid.") +AnnotationAssertion( "GO:0019663") +AnnotationAssertion( "acetate breakdown") +AnnotationAssertion( "acetate catabolism") +AnnotationAssertion( "acetate degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "homoacetate catabolic process") +AnnotationAssertion( "GO:0045733") +AnnotationAssertion(rdfs:label "acetate catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of acetate catabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of acetate, the anion of acetic acid.") +AnnotationAssertion( "regulation of acetate breakdown") +AnnotationAssertion( "regulation of acetate catabolism") +AnnotationAssertion( "regulation of acetate degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045734") +AnnotationAssertion(rdfs:label "regulation of acetate catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (negative regulation of G protein-coupled receptor signaling pathway) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of G protein-coupled receptor signaling pathway.") +AnnotationAssertion( "down regulation of G-protein coupled receptor protein signaling pathway") +AnnotationAssertion( "down-regulation of G-protein coupled receptor protein signaling pathway") +AnnotationAssertion( "downregulation of G-protein coupled receptor protein signaling pathway") +AnnotationAssertion( "negative regulation of G protein coupled receptor protein signaling pathway") +AnnotationAssertion( "negative regulation of G protein coupled receptor protein signalling pathway") +AnnotationAssertion( "negative regulation of G-protein coupled receptor protein signaling pathway") +AnnotationAssertion( "negative regulation of G-protein coupled receptor protein signalling pathway") +AnnotationAssertion( "negative regulation of G-protein-coupled receptor protein signalling pathway") +AnnotationAssertion( "negative regulation of GPCR protein signaling pathway") +AnnotationAssertion( "negative regulation of GPCR protein signalling pathway") +AnnotationAssertion( "inhibition of G-protein coupled receptor protein signaling pathway") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045744") +AnnotationAssertion(rdfs:label "negative regulation of G protein-coupled receptor signaling pathway") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of G protein-coupled receptor signaling pathway) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of G protein-coupled receptor signaling pathway activity.") +AnnotationAssertion( "positive regulation of G protein coupled receptor protein signaling pathway") +AnnotationAssertion( "positive regulation of G protein coupled receptor protein signalling pathway") +AnnotationAssertion( "positive regulation of G-protein coupled receptor protein signaling pathway") +AnnotationAssertion( "positive regulation of G-protein coupled receptor protein signalling pathway") +AnnotationAssertion( "positive regulation of G-protein-coupled receptor protein signaling pathway") +AnnotationAssertion( "positive regulation of G-protein-coupled receptor protein signalling pathway") +AnnotationAssertion( "positive regulation of GPCR protein signaling pathway") +AnnotationAssertion( "positive regulation of GPCR protein signalling pathway") +AnnotationAssertion( "up regulation of G-protein coupled receptor protein signaling pathway") +AnnotationAssertion( "up-regulation of G-protein coupled receptor protein signaling pathway") +AnnotationAssertion( "upregulation of G-protein coupled receptor protein signaling pathway") +AnnotationAssertion( "activation of G-protein coupled receptor protein signaling pathway") +AnnotationAssertion( "stimulation of G-protein coupled receptor protein signaling pathway") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045745") +AnnotationAssertion(rdfs:label "positive regulation of G protein-coupled receptor signaling pathway") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of acetate catabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of acetate.") +AnnotationAssertion( "down regulation of acetate catabolic process") +AnnotationAssertion( "down-regulation of acetate catabolic process") +AnnotationAssertion( "downregulation of acetate catabolic process") +AnnotationAssertion( "negative regulation of acetate breakdown") +AnnotationAssertion( "negative regulation of acetate catabolism") +AnnotationAssertion( "negative regulation of acetate degradation") +AnnotationAssertion( "inhibition of acetate catabolic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045753") +AnnotationAssertion(rdfs:label "negative regulation of acetate catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of acetate catabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of acetate.") +AnnotationAssertion( "positive regulation of acetate breakdown") +AnnotationAssertion( "positive regulation of acetate catabolism") +AnnotationAssertion( "positive regulation of acetate degradation") +AnnotationAssertion( "up regulation of acetate catabolic process") +AnnotationAssertion( "up-regulation of acetate catabolic process") +AnnotationAssertion( "upregulation of acetate catabolic process") +AnnotationAssertion( "activation of acetate catabolic process") +AnnotationAssertion( "stimulation of acetate catabolic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045754") +AnnotationAssertion(rdfs:label "positive regulation of acetate catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of action potential) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of action potential creation, propagation or termination. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.") +AnnotationAssertion( "down regulation of action potential") +AnnotationAssertion( "down-regulation of action potential") +AnnotationAssertion( "downregulation of action potential") +AnnotationAssertion( "inhibition of action potential") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045759") +AnnotationAssertion(rdfs:label "negative regulation of action potential") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (positive regulation of action potential) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of action potential creation, propagation or termination. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.") +AnnotationAssertion( "up regulation of action potential") +AnnotationAssertion( "up-regulation of action potential") +AnnotationAssertion( "upregulation of action potential") +AnnotationAssertion( "activation of action potential") +AnnotationAssertion( "stimulation of action potential") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045760") +AnnotationAssertion(rdfs:label "positive regulation of action potential") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (negative regulation of cellular amino acid metabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amino acid.") +AnnotationAssertion( "down regulation of amino acid metabolic process") +AnnotationAssertion( "down-regulation of amino acid metabolic process") +AnnotationAssertion( "downregulation of amino acid metabolic process") +AnnotationAssertion( "negative regulation of amino acid metabolism") +AnnotationAssertion( "inhibition of amino acid metabolic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045763") +AnnotationAssertion(rdfs:label "negative regulation of cellular amino acid metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of amino acid metabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amino acid.") +AnnotationAssertion( "positive regulation of amino acid metabolism") +AnnotationAssertion( "positive regulation of cellular amino acid metabolic process") +AnnotationAssertion( "up regulation of amino acid metabolic process") +AnnotationAssertion( "up-regulation of amino acid metabolic process") +AnnotationAssertion( "upregulation of amino acid metabolic process") +AnnotationAssertion( "activation of amino acid metabolic process") +AnnotationAssertion( "stimulation of amino acid metabolic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045764") +AnnotationAssertion(rdfs:label "positive regulation of amino acid metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of angiogenesis) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of angiogenesis.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045765") +AnnotationAssertion(rdfs:label "regulation of angiogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of angiogenesis) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases angiogenesis.") +AnnotationAssertion( "up regulation of angiogenesis") +AnnotationAssertion( "up-regulation of angiogenesis") +AnnotationAssertion( "upregulation of angiogenesis") +AnnotationAssertion( "activation of angiogenesis") +AnnotationAssertion( "stimulation of angiogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045766") +AnnotationAssertion(rdfs:label "positive regulation of angiogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of asymmetric cell division) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of asymmetric cell division.") +AnnotationAssertion( "down regulation of asymmetric cell division") +AnnotationAssertion( "down-regulation of asymmetric cell division") +AnnotationAssertion( "downregulation of asymmetric cell division") +AnnotationAssertion( "inhibition of asymmetric cell division") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045769") +AnnotationAssertion(rdfs:label "negative regulation of asymmetric cell division") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of asymmetric cell division) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of asymmetric cell division.") +AnnotationAssertion( "up regulation of asymmetric cell division") +AnnotationAssertion( "up-regulation of asymmetric cell division") +AnnotationAssertion( "upregulation of asymmetric cell division") +AnnotationAssertion( "activation of asymmetric cell division") +AnnotationAssertion( "stimulation of asymmetric cell division") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045770") +AnnotationAssertion(rdfs:label "positive regulation of asymmetric cell division") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of ossification) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance.") +AnnotationAssertion( "positive regulation of bone biosynthesis") +AnnotationAssertion( "positive regulation of bone formation") +AnnotationAssertion( "up regulation of ossification") +AnnotationAssertion( "up-regulation of ossification") +AnnotationAssertion( "upregulation of ossification") +AnnotationAssertion( "activation of ossification") +AnnotationAssertion( "stimulation of ossification") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045778") +AnnotationAssertion(rdfs:label "positive regulation of ossification") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of bone resorption) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of bone resorption.") +AnnotationAssertion( "down regulation of bone resorption") +AnnotationAssertion( "down-regulation of bone resorption") +AnnotationAssertion( "downregulation of bone resorption") +AnnotationAssertion( "inhibition of bone resorption") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045779") +AnnotationAssertion(rdfs:label "negative regulation of bone resorption") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (positive regulation of bone resorption) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of bone resorption.") +AnnotationAssertion( "up regulation of bone resorption") +AnnotationAssertion( "up-regulation of bone resorption") +AnnotationAssertion( "upregulation of bone resorption") +AnnotationAssertion( "activation of bone resorption") +AnnotationAssertion( "stimulation of bone resorption") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045780") +AnnotationAssertion(rdfs:label "positive regulation of bone resorption") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of cell adhesion) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of cell adhesion.") +AnnotationAssertion( "up regulation of cell adhesion") +AnnotationAssertion( "up-regulation of cell adhesion") +AnnotationAssertion( "upregulation of cell adhesion") +AnnotationAssertion( "activation of cell adhesion") +AnnotationAssertion( "stimulation of cell adhesion") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045785") +AnnotationAssertion(rdfs:label "positive regulation of cell adhesion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of cell cycle) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:go_curators") Annotation( "GOC:tb") "Any process that stops, prevents or reduces the rate or extent of progression through the cell cycle.") +AnnotationAssertion( "down regulation of progression through cell cycle") +AnnotationAssertion( "down-regulation of progression through cell cycle") +AnnotationAssertion( "downregulation of progression through cell cycle") +AnnotationAssertion( "negative regulation of cell cycle progression") +AnnotationAssertion( "negative regulation of progression through cell cycle") +AnnotationAssertion( "inhibition of progression through cell cycle") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045786") +AnnotationAssertion(rdfs:label "negative regulation of cell cycle") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of cell cycle) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the rate or extent of progression through the cell cycle.") +AnnotationAssertion( "positive regulation of cell cycle progression") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "positive regulation of progression through cell cycle") +AnnotationAssertion( "up regulation of progression through cell cycle") +AnnotationAssertion( "up-regulation of progression through cell cycle") +AnnotationAssertion( "upregulation of progression through cell cycle") +AnnotationAssertion( "activation of progression through cell cycle") +AnnotationAssertion( "stimulation of progression through cell cycle") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045787") +AnnotationAssertion(rdfs:label "positive regulation of cell cycle") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of eclosion) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of eclosion.") +AnnotationAssertion( "down regulation of eclosion") +AnnotationAssertion( "down-regulation of eclosion") +AnnotationAssertion( "downregulation of eclosion") +AnnotationAssertion( "inhibition of eclosion") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045804") +AnnotationAssertion(rdfs:label "negative regulation of eclosion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (positive regulation of eclosion) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of eclosion.") +AnnotationAssertion( "up regulation of eclosion") +AnnotationAssertion( "up-regulation of eclosion") +AnnotationAssertion( "upregulation of eclosion") +AnnotationAssertion( "activation of eclosion") +AnnotationAssertion( "stimulation of eclosion") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045805") +AnnotationAssertion(rdfs:label "positive regulation of eclosion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of endocytosis) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of endocytosis.") +AnnotationAssertion( "down regulation of endocytosis") +AnnotationAssertion( "down-regulation of endocytosis") +AnnotationAssertion( "downregulation of endocytosis") +AnnotationAssertion( "inhibition of endocytosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045806") +AnnotationAssertion(rdfs:label "negative regulation of endocytosis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (positive regulation of endocytosis) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of endocytosis.") +AnnotationAssertion( "up regulation of endocytosis") +AnnotationAssertion( "up-regulation of endocytosis") +AnnotationAssertion( "upregulation of endocytosis") +AnnotationAssertion( "activation of endocytosis") +AnnotationAssertion( "stimulation of endocytosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045807") +AnnotationAssertion(rdfs:label "positive regulation of endocytosis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (negative regulation of glycogen catabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glycogen.") +AnnotationAssertion( "down regulation of glycogen catabolic process") +AnnotationAssertion( "down-regulation of glycogen catabolic process") +AnnotationAssertion( "downregulation of glycogen catabolic process") +AnnotationAssertion( "negative regulation of glycogen breakdown") +AnnotationAssertion( "negative regulation of glycogen catabolism") +AnnotationAssertion( "negative regulation of glycogen degradation") +AnnotationAssertion(Annotation( "GOC:sl") "negative regulation of glycogenolysis") +AnnotationAssertion( "inhibition of glycogen catabolic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045818") +AnnotationAssertion(rdfs:label "negative regulation of glycogen catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of glycogen catabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glycogen.") +AnnotationAssertion( "positive regulation of glycogen breakdown") +AnnotationAssertion( "positive regulation of glycogen catabolism") +AnnotationAssertion( "positive regulation of glycogen degradation") +AnnotationAssertion(Annotation( "GOC:sl") "positive regulation of glycogenolysis") +AnnotationAssertion( "up regulation of glycogen catabolic process") +AnnotationAssertion( "up-regulation of glycogen catabolic process") +AnnotationAssertion( "upregulation of glycogen catabolic process") +AnnotationAssertion( "activation of glycogen catabolic process") +AnnotationAssertion( "stimulation of glycogen catabolic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045819") +AnnotationAssertion(rdfs:label "positive regulation of glycogen catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of heart contraction) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of heart contraction.") +AnnotationAssertion( "down regulation of heart contraction") +AnnotationAssertion( "down-regulation of heart contraction") +AnnotationAssertion( "downregulation of heart contraction") +AnnotationAssertion( "inhibition of heart contraction") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "negative regulation of cardiac contraction") +AnnotationAssertion( "GO:0045822") +AnnotationAssertion(rdfs:label "negative regulation of heart contraction") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of heart contraction) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of heart contraction.") +AnnotationAssertion( "positive regulation of cardiac contraction") +AnnotationAssertion( "up regulation of heart contraction") +AnnotationAssertion( "up-regulation of heart contraction") +AnnotationAssertion( "upregulation of heart contraction") +AnnotationAssertion( "activation of heart contraction") +AnnotationAssertion( "stimulation of heart contraction") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045823") +AnnotationAssertion(rdfs:label "positive regulation of heart contraction") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of isoprenoid metabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving isoprenoid.") +AnnotationAssertion( "down regulation of isoprenoid metabolic process") +AnnotationAssertion( "down-regulation of isoprenoid metabolic process") +AnnotationAssertion( "downregulation of isoprenoid metabolic process") +AnnotationAssertion( "negative regulation of isoprenoid metabolism") +AnnotationAssertion( "inhibition of isoprenoid metabolic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045827") +AnnotationAssertion(rdfs:label "negative regulation of isoprenoid metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of isoprenoid metabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving isoprenoid.") +AnnotationAssertion( "positive regulation of isoprenoid metabolism") +AnnotationAssertion( "up regulation of isoprenoid metabolic process") +AnnotationAssertion( "up-regulation of isoprenoid metabolic process") +AnnotationAssertion( "upregulation of isoprenoid metabolic process") +AnnotationAssertion( "activation of isoprenoid metabolic process") +AnnotationAssertion( "stimulation of isoprenoid metabolic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045828") +AnnotationAssertion(rdfs:label "positive regulation of isoprenoid metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of isotype switching) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of isotype switching.") +AnnotationAssertion( "down regulation of isotype switching") +AnnotationAssertion( "down-regulation of isotype switching") +AnnotationAssertion( "downregulation of isotype switching") +AnnotationAssertion( "negative regulation of class switch recombination") +AnnotationAssertion( "negative regulation of class switching") +AnnotationAssertion( "negative regulation of isotype switch recombination") +AnnotationAssertion( "inhibition of isotype switching") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045829") +AnnotationAssertion(rdfs:label "negative regulation of isotype switching") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (positive regulation of isotype switching) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of isotype switching.") +AnnotationAssertion( "positive regulation of class switch recombination") +AnnotationAssertion( "positive regulation of class switching") +AnnotationAssertion( "positive regulation of isotype switch recombination") +AnnotationAssertion( "up regulation of isotype switching") +AnnotationAssertion( "up-regulation of isotype switching") +AnnotationAssertion( "upregulation of isotype switching") +AnnotationAssertion( "activation of isotype switching") +AnnotationAssertion( "stimulation of isotype switching") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045830") +AnnotationAssertion(rdfs:label "positive regulation of isotype switching") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (negative regulation of lipid metabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving lipids.") +AnnotationAssertion( "down regulation of lipid metabolic process") +AnnotationAssertion( "down-regulation of lipid metabolic process") +AnnotationAssertion( "downregulation of lipid metabolic process") +AnnotationAssertion( "negative regulation of lipid metabolism") +AnnotationAssertion( "inhibition of lipid metabolic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045833") +AnnotationAssertion(rdfs:label "negative regulation of lipid metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of lipid metabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving lipids.") +AnnotationAssertion( "positive regulation of lipid metabolism") +AnnotationAssertion( "up regulation of lipid metabolic process") +AnnotationAssertion( "up-regulation of lipid metabolic process") +AnnotationAssertion( "upregulation of lipid metabolic process") +AnnotationAssertion( "activation of lipid metabolic process") +AnnotationAssertion( "stimulation of lipid metabolic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045834") +AnnotationAssertion(rdfs:label "positive regulation of lipid metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of meiotic nuclear division) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of meiosis.") +AnnotationAssertion( "down regulation of meiosis") +AnnotationAssertion( "down-regulation of meiosis") +AnnotationAssertion( "downregulation of meiosis") +AnnotationAssertion( "negative regulation of meiosis") +AnnotationAssertion( "inhibition of meiosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045835") +AnnotationAssertion(rdfs:label "negative regulation of meiotic nuclear division") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (positive regulation of meiotic nuclear division) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of meiosis.") +AnnotationAssertion( "positive regulation of meiosis") +AnnotationAssertion( "up regulation of meiosis") +AnnotationAssertion( "up-regulation of meiosis") +AnnotationAssertion( "upregulation of meiosis") +AnnotationAssertion( "activation of meiosis") +AnnotationAssertion( "stimulation of meiosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045836") +AnnotationAssertion(rdfs:label "positive regulation of meiotic nuclear division") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (negative regulation of mitotic nuclear division) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:go_curators") Annotation( "GOC:tb") "Any process that stops, prevents or reduces the rate or extent of mitosis. Mitosis is the division of the eukaryotic cell nucleus to produce two daughter nuclei that, usually, contain the identical chromosome complement to their mother.") +AnnotationAssertion( "down regulation of mitosis") +AnnotationAssertion( "down-regulation of mitosis") +AnnotationAssertion( "downregulation of mitosis") +AnnotationAssertion( "negative regulation of mitosis") +AnnotationAssertion( "inhibition of mitosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045839") +AnnotationAssertion(rdfs:label "negative regulation of mitotic nuclear division") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (positive regulation of mitotic nuclear division) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of mitosis.") +AnnotationAssertion( "positive regulation of mitosis") +AnnotationAssertion( "up regulation of mitosis") +AnnotationAssertion( "up-regulation of mitosis") +AnnotationAssertion( "upregulation of mitosis") +AnnotationAssertion( "activation of mitosis") +AnnotationAssertion( "mitogenic activity") +AnnotationAssertion( "stimulation of mitosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045840") +AnnotationAssertion(rdfs:label "positive regulation of mitotic nuclear division") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (negative regulation of striated muscle tissue development) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle development.") +AnnotationAssertion( "down regulation of striated muscle development") +AnnotationAssertion( "down-regulation of striated muscle development") +AnnotationAssertion( "downregulation of striated muscle development") +AnnotationAssertion( "inhibition of striated muscle development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045843") +AnnotationAssertion(rdfs:label "negative regulation of striated muscle tissue development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (positive regulation of striated muscle tissue development) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of striated muscle development.") +AnnotationAssertion( "up regulation of striated muscle development") +AnnotationAssertion( "up-regulation of striated muscle development") +AnnotationAssertion( "upregulation of striated muscle development") +AnnotationAssertion( "activation of striated muscle development") +AnnotationAssertion( "stimulation of striated muscle development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045844") +AnnotationAssertion(rdfs:label "positive regulation of striated muscle tissue development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (pH reduction) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that reduces the internal pH of an organism, part of an organism or a cell, measured by the concentration of the hydrogen ion.") +AnnotationAssertion( "acidification") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045851") +AnnotationAssertion(rdfs:label "pH reduction") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (pH elevation) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that increases the internal pH of an organism, part of an organism or a cell, measured by the concentration of the hydrogen ion.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045852") +AnnotationAssertion(rdfs:label "pH elevation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of protein kinase activity) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of protein kinase activity.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045859") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "regulation of protein kinase activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (positive regulation of protein kinase activity) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of protein kinase activity.") +AnnotationAssertion( "up regulation of protein kinase activity") +AnnotationAssertion( "up-regulation of protein kinase activity") +AnnotationAssertion( "upregulation of protein kinase activity") +AnnotationAssertion( "stimulation of protein kinase activity") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045860") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "positive regulation of protein kinase activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (negative regulation of proteolysis) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein.") +AnnotationAssertion( "down regulation of proteolysis") +AnnotationAssertion( "down-regulation of proteolysis") +AnnotationAssertion( "downregulation of proteolysis") +AnnotationAssertion( "negative regulation of peptidolysis") +AnnotationAssertion( "inhibition of proteolysis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045861") +AnnotationAssertion(rdfs:label "negative regulation of proteolysis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (positive regulation of proteolysis) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein.") +AnnotationAssertion( "positive regulation of peptidolysis") +AnnotationAssertion( "up regulation of proteolysis") +AnnotationAssertion( "up-regulation of proteolysis") +AnnotationAssertion( "upregulation of proteolysis") +AnnotationAssertion( "activation of proteolysis") +AnnotationAssertion( "stimulation of proteolysis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045862") +AnnotationAssertion(rdfs:label "positive regulation of proteolysis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (negative regulation of translational elongation) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of translational elongation.") +AnnotationAssertion( "down regulation of translational elongation") +AnnotationAssertion( "down-regulation of translational elongation") +AnnotationAssertion( "downregulation of translational elongation") +AnnotationAssertion( "inhibition of translational elongation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045900") +AnnotationAssertion(rdfs:label "negative regulation of translational elongation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (positive regulation of translational elongation) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of translational elongation.") +AnnotationAssertion( "up regulation of translational elongation") +AnnotationAssertion( "up-regulation of translational elongation") +AnnotationAssertion( "upregulation of translational elongation") +AnnotationAssertion( "activation of translational elongation") +AnnotationAssertion( "stimulation of translational elongation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045901") +AnnotationAssertion(rdfs:label "positive regulation of translational elongation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (negative regulation of translational termination) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of translational termination.") +AnnotationAssertion( "down regulation of translational termination") +AnnotationAssertion( "down-regulation of translational termination") +AnnotationAssertion( "downregulation of translational termination") +AnnotationAssertion( "inhibition of translational termination") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045904") +AnnotationAssertion(rdfs:label "negative regulation of translational termination") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (positive regulation of translational termination) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of translational termination.") +AnnotationAssertion( "up regulation of translational termination") +AnnotationAssertion( "up-regulation of translational termination") +AnnotationAssertion( "upregulation of translational termination") +AnnotationAssertion( "activation of translational termination") +AnnotationAssertion( "stimulation of translational termination") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045905") +AnnotationAssertion(rdfs:label "positive regulation of translational termination") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (negative regulation of DNA recombination) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of DNA recombination.") +AnnotationAssertion( "down regulation of DNA recombination") +AnnotationAssertion( "down-regulation of DNA recombination") +AnnotationAssertion( "downregulation of DNA recombination") +AnnotationAssertion( "inhibition of DNA recombination") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045910") +AnnotationAssertion(rdfs:label "negative regulation of DNA recombination") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of DNA recombination) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of DNA recombination.") +AnnotationAssertion( "up regulation of DNA recombination") +AnnotationAssertion( "up-regulation of DNA recombination") +AnnotationAssertion( "upregulation of DNA recombination") +AnnotationAssertion( "activation of DNA recombination") +AnnotationAssertion( "stimulation of DNA recombination") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045911") +AnnotationAssertion(rdfs:label "positive regulation of DNA recombination") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of carbohydrate metabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving carbohydrate.") +AnnotationAssertion( "down regulation of carbohydrate metabolic process") +AnnotationAssertion( "down-regulation of carbohydrate metabolic process") +AnnotationAssertion( "downregulation of carbohydrate metabolic process") +AnnotationAssertion( "negative regulation of carbohydrate metabolism") +AnnotationAssertion( "inhibition of carbohydrate metabolic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045912") +AnnotationAssertion(rdfs:label "negative regulation of carbohydrate metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of carbohydrate metabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving carbohydrate.") +AnnotationAssertion( "positive regulation of carbohydrate metabolism") +AnnotationAssertion( "up regulation of carbohydrate metabolic process") +AnnotationAssertion( "up-regulation of carbohydrate metabolic process") +AnnotationAssertion( "upregulation of carbohydrate metabolic process") +AnnotationAssertion( "activation of carbohydrate metabolic process") +AnnotationAssertion( "stimulation of carbohydrate metabolic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045913") +AnnotationAssertion(rdfs:label "positive regulation of carbohydrate metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of catecholamine metabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving catecholamine.") +AnnotationAssertion( "down regulation of catecholamine metabolic process") +AnnotationAssertion( "down-regulation of catecholamine metabolic process") +AnnotationAssertion( "downregulation of catecholamine metabolic process") +AnnotationAssertion( "negative regulation of catecholamine metabolism") +AnnotationAssertion( "inhibition of catecholamine metabolic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045914") +AnnotationAssertion(rdfs:label "negative regulation of catecholamine metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of catecholamine metabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving catecholamine.") +AnnotationAssertion( "positive regulation of catecholamine metabolism") +AnnotationAssertion( "up regulation of catecholamine metabolic process") +AnnotationAssertion( "up-regulation of catecholamine metabolic process") +AnnotationAssertion( "upregulation of catecholamine metabolic process") +AnnotationAssertion( "activation of catecholamine metabolic process") +AnnotationAssertion( "stimulation of catecholamine metabolic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045915") +AnnotationAssertion(rdfs:label "positive regulation of catecholamine metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of exocytosis) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of exocytosis.") +AnnotationAssertion( "down regulation of exocytosis") +AnnotationAssertion( "down-regulation of exocytosis") +AnnotationAssertion( "downregulation of exocytosis") +AnnotationAssertion( "inhibition of exocytosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045920") +AnnotationAssertion(rdfs:label "negative regulation of exocytosis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of exocytosis) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of exocytosis.") +AnnotationAssertion( "up regulation of exocytosis") +AnnotationAssertion( "up-regulation of exocytosis") +AnnotationAssertion( "upregulation of exocytosis") +AnnotationAssertion( "activation of exocytosis") +AnnotationAssertion( "stimulation of exocytosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045921") +AnnotationAssertion(rdfs:label "positive regulation of exocytosis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of fatty acid metabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving fatty acids.") +AnnotationAssertion( "down regulation of fatty acid metabolic process") +AnnotationAssertion( "down-regulation of fatty acid metabolic process") +AnnotationAssertion( "downregulation of fatty acid metabolic process") +AnnotationAssertion( "negative regulation of fatty acid metabolism") +AnnotationAssertion( "inhibition of fatty acid metabolic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045922") +AnnotationAssertion(rdfs:label "negative regulation of fatty acid metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of fatty acid metabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving fatty acids.") +AnnotationAssertion( "positive regulation of fatty acid metabolism") +AnnotationAssertion( "up regulation of fatty acid metabolic process") +AnnotationAssertion( "up-regulation of fatty acid metabolic process") +AnnotationAssertion( "upregulation of fatty acid metabolic process") +AnnotationAssertion( "activation of fatty acid metabolic process") +AnnotationAssertion( "stimulation of fatty acid metabolic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045923") +AnnotationAssertion(rdfs:label "positive regulation of fatty acid metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of growth) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents or reduces the rate or extent of growth, the increase in size or mass of all or part of an organism.") +AnnotationAssertion( "down regulation of growth") +AnnotationAssertion( "down-regulation of growth") +AnnotationAssertion( "downregulation of growth") +AnnotationAssertion( "inhibition of growth") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045926") +AnnotationAssertion(rdfs:label "negative regulation of growth") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of growth) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the rate or extent of growth, the increase in size or mass of all or part of an organism.") +AnnotationAssertion( "up regulation of growth") +AnnotationAssertion( "up-regulation of growth") +AnnotationAssertion( "upregulation of growth") +AnnotationAssertion( "activation of growth") +AnnotationAssertion( "stimulation of growth") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045927") +AnnotationAssertion(rdfs:label "positive regulation of growth") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of juvenile hormone metabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving juvenile hormone.") +AnnotationAssertion( "down regulation of juvenile hormone metabolic process") +AnnotationAssertion( "down-regulation of juvenile hormone metabolic process") +AnnotationAssertion( "downregulation of juvenile hormone metabolic process") +AnnotationAssertion( "negative regulation of juvenile hormone metabolism") +AnnotationAssertion( "inhibition of juvenile hormone metabolic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045928") +AnnotationAssertion(rdfs:label "negative regulation of juvenile hormone metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of juvenile hormone metabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving juvenile hormone.") +AnnotationAssertion( "positive regulation of juvenile hormone metabolism") +AnnotationAssertion( "up regulation of juvenile hormone metabolic process") +AnnotationAssertion( "up-regulation of juvenile hormone metabolic process") +AnnotationAssertion( "upregulation of juvenile hormone metabolic process") +AnnotationAssertion( "activation of juvenile hormone metabolic process") +AnnotationAssertion( "stimulation of juvenile hormone metabolic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045929") +AnnotationAssertion(rdfs:label "positive regulation of juvenile hormone metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of mitotic cell cycle) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:go_curators") Annotation( "GOC:tb") "Any process that stops, prevents or reduces the rate or extent of progression through the mitotic cell cycle.") +AnnotationAssertion( "down regulation of progression through mitotic cell cycle") +AnnotationAssertion( "down-regulation of progression through mitotic cell cycle") +AnnotationAssertion( "downregulation of progression through mitotic cell cycle") +AnnotationAssertion( "negative regulation of mitotic cell cycle progression") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "negative regulation of progression through mitotic cell cycle") +AnnotationAssertion( "inhibition of progression through mitotic cell cycle") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045930") +AnnotationAssertion(rdfs:label "negative regulation of mitotic cell cycle") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of mitotic cell cycle) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:go_curators") Annotation( "GOC:tb") "Any process that activates or increases the rate or extent of progression through the mitotic cell cycle.") +AnnotationAssertion( "positive regulation of mitotic cell cycle progression") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "positive regulation of progression through mitotic cell cycle") +AnnotationAssertion( "up regulation of progression through mitotic cell cycle") +AnnotationAssertion( "up-regulation of progression through mitotic cell cycle") +AnnotationAssertion( "upregulation of progression through mitotic cell cycle") +AnnotationAssertion( "activation of progression through mitotic cell cycle") +AnnotationAssertion( "stimulation of progression through mitotic cell cycle") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045931") +AnnotationAssertion(rdfs:label "positive regulation of mitotic cell cycle") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of muscle contraction) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of muscle contraction.") +AnnotationAssertion( "down regulation of muscle contraction") +AnnotationAssertion( "down-regulation of muscle contraction") +AnnotationAssertion( "downregulation of muscle contraction") +AnnotationAssertion( "inhibition of muscle contraction") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045932") +AnnotationAssertion(rdfs:label "negative regulation of muscle contraction") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of muscle contraction) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of muscle contraction.") +AnnotationAssertion( "up regulation of muscle contraction") +AnnotationAssertion( "up-regulation of muscle contraction") +AnnotationAssertion( "upregulation of muscle contraction") +AnnotationAssertion( "activation of muscle contraction") +AnnotationAssertion( "stimulation of muscle contraction") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045933") +AnnotationAssertion(rdfs:label "positive regulation of muscle contraction") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of nucleobase-containing compound metabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any cellular process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids.") +AnnotationAssertion( "down regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process") +AnnotationAssertion( "down-regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process") +AnnotationAssertion( "downregulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process") +AnnotationAssertion( "negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism") +AnnotationAssertion( "inhibition of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process") +AnnotationAssertion( "GO:0045934") +AnnotationAssertion(rdfs:label "negative regulation of nucleobase-containing compound metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of nucleobase-containing compound metabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any cellular process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids.") +AnnotationAssertion( "positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism") +AnnotationAssertion( "up regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process") +AnnotationAssertion( "up-regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process") +AnnotationAssertion( "upregulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process") +AnnotationAssertion( "activation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process") +AnnotationAssertion( "stimulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process") +AnnotationAssertion( "GO:0045935") +AnnotationAssertion(rdfs:label "positive regulation of nucleobase-containing compound metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of phosphate metabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving phosphates.") +AnnotationAssertion( "down regulation of phosphate metabolic process") +AnnotationAssertion( "down-regulation of phosphate metabolic process") +AnnotationAssertion( "downregulation of phosphate metabolic process") +AnnotationAssertion( "negative regulation of phosphate metabolism") +AnnotationAssertion( "inhibition of phosphate metabolic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045936") +AnnotationAssertion(rdfs:label "negative regulation of phosphate metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of phosphate metabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving phosphates.") +AnnotationAssertion( "positive regulation of phosphate metabolism") +AnnotationAssertion( "up regulation of phosphate metabolic process") +AnnotationAssertion( "up-regulation of phosphate metabolic process") +AnnotationAssertion( "upregulation of phosphate metabolic process") +AnnotationAssertion( "activation of phosphate metabolic process") +AnnotationAssertion( "stimulation of phosphate metabolic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045937") +AnnotationAssertion(rdfs:label "positive regulation of phosphate metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of circadian sleep/wake cycle, sleep) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the duration or quality of sleep, a readily reversible state of reduced awareness and metabolic activity that occurs periodically in many animals.") +AnnotationAssertion( "positive regulation of sleep") +AnnotationAssertion( "up regulation of circadian sleep/wake cycle, sleep") +AnnotationAssertion( "up-regulation of circadian sleep/wake cycle, sleep") +AnnotationAssertion( "upregulation of circadian sleep/wake cycle, sleep") +AnnotationAssertion( "activation of circadian sleep/wake cycle, sleep") +AnnotationAssertion( "stimulation of circadian sleep/wake cycle, sleep") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045938") +AnnotationAssertion(rdfs:label "positive regulation of circadian sleep/wake cycle, sleep") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of steroid metabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving steroids.") +AnnotationAssertion( "down regulation of steroid metabolic process") +AnnotationAssertion( "down-regulation of steroid metabolic process") +AnnotationAssertion( "downregulation of steroid metabolic process") +AnnotationAssertion( "negative regulation of steroid metabolism") +AnnotationAssertion( "inhibition of steroid metabolic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045939") +AnnotationAssertion(rdfs:label "negative regulation of steroid metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of steroid metabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving steroids.") +AnnotationAssertion( "positive regulation of steroid metabolism") +AnnotationAssertion( "up regulation of steroid metabolic process") +AnnotationAssertion( "up-regulation of steroid metabolic process") +AnnotationAssertion( "upregulation of steroid metabolic process") +AnnotationAssertion( "activation of steroid metabolic process") +AnnotationAssertion( "stimulation of steroid metabolic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045940") +AnnotationAssertion(rdfs:label "positive regulation of steroid metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of translational initiation) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of translational initiation.") +AnnotationAssertion( "down regulation of translational initiation") +AnnotationAssertion( "down-regulation of translational initiation") +AnnotationAssertion( "downregulation of translational initiation") +AnnotationAssertion( "inhibition of translational initiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045947") +AnnotationAssertion(rdfs:label "negative regulation of translational initiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (positive regulation of translational initiation) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of translational initiation.") +AnnotationAssertion( "up regulation of translational initiation") +AnnotationAssertion( "up-regulation of translational initiation") +AnnotationAssertion( "upregulation of translational initiation") +AnnotationAssertion( "activation of translational initiation") +AnnotationAssertion( "stimulation of translational initiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045948") +AnnotationAssertion(rdfs:label "positive regulation of translational initiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of juvenile hormone catabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of juvenile hormone.") +AnnotationAssertion( "regulation of juvenile hormone breakdown") +AnnotationAssertion( "regulation of juvenile hormone catabolism") +AnnotationAssertion( "regulation of juvenile hormone degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045952") +AnnotationAssertion(rdfs:label "regulation of juvenile hormone catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of dopamine metabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving dopamine.") +AnnotationAssertion( "down regulation of dopamine metabolic process") +AnnotationAssertion( "down-regulation of dopamine metabolic process") +AnnotationAssertion( "downregulation of dopamine metabolic process") +AnnotationAssertion( "negative regulation of dopamine metabolism") +AnnotationAssertion( "inhibition of dopamine metabolic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045963") +AnnotationAssertion(rdfs:label "negative regulation of dopamine metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of dopamine metabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving dopamine.") +AnnotationAssertion( "positive regulation of dopamine metabolism") +AnnotationAssertion( "up regulation of dopamine metabolic process") +AnnotationAssertion( "up-regulation of dopamine metabolic process") +AnnotationAssertion( "upregulation of dopamine metabolic process") +AnnotationAssertion( "activation of dopamine metabolic process") +AnnotationAssertion( "stimulation of dopamine metabolic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045964") +AnnotationAssertion(rdfs:label "positive regulation of dopamine metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of juvenile hormone biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of juvenile hormone.") +AnnotationAssertion( "down regulation of juvenile hormone biosynthetic process") +AnnotationAssertion( "down-regulation of juvenile hormone biosynthetic process") +AnnotationAssertion( "downregulation of juvenile hormone biosynthetic process") +AnnotationAssertion( "negative regulation of juvenile hormone anabolism") +AnnotationAssertion( "negative regulation of juvenile hormone biosynthesis") +AnnotationAssertion( "negative regulation of juvenile hormone formation") +AnnotationAssertion( "negative regulation of juvenile hormone synthesis") +AnnotationAssertion( "inhibition of juvenile hormone biosynthetic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045968") +AnnotationAssertion(rdfs:label "negative regulation of juvenile hormone biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of juvenile hormone biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of juvenile hormone.") +AnnotationAssertion( "positive regulation of juvenile hormone anabolism") +AnnotationAssertion( "positive regulation of juvenile hormone biosynthesis") +AnnotationAssertion( "positive regulation of juvenile hormone formation") +AnnotationAssertion( "positive regulation of juvenile hormone synthesis") +AnnotationAssertion( "up regulation of juvenile hormone biosynthetic process") +AnnotationAssertion( "up-regulation of juvenile hormone biosynthetic process") +AnnotationAssertion( "upregulation of juvenile hormone biosynthetic process") +AnnotationAssertion( "activation of juvenile hormone biosynthetic process") +AnnotationAssertion( "stimulation of juvenile hormone biosynthetic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045969") +AnnotationAssertion(rdfs:label "positive regulation of juvenile hormone biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of juvenile hormone catabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of juvenile hormone.") +AnnotationAssertion( "down regulation of juvenile hormone catabolic process") +AnnotationAssertion( "down-regulation of juvenile hormone catabolic process") +AnnotationAssertion( "downregulation of juvenile hormone catabolic process") +AnnotationAssertion( "negative regulation of juvenile hormone breakdown") +AnnotationAssertion( "negative regulation of juvenile hormone catabolism") +AnnotationAssertion( "negative regulation of juvenile hormone degradation") +AnnotationAssertion( "inhibition of juvenile hormone catabolic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045970") +AnnotationAssertion(rdfs:label "negative regulation of juvenile hormone catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of juvenile hormone catabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of juvenile hormone.") +AnnotationAssertion( "positive regulation of juvenile hormone breakdown") +AnnotationAssertion( "positive regulation of juvenile hormone catabolism") +AnnotationAssertion( "positive regulation of juvenile hormone degradation") +AnnotationAssertion( "up regulation of juvenile hormone catabolic process") +AnnotationAssertion( "up-regulation of juvenile hormone catabolic process") +AnnotationAssertion( "upregulation of juvenile hormone catabolic process") +AnnotationAssertion( "activation of juvenile hormone catabolic process") +AnnotationAssertion( "stimulation of juvenile hormone catabolic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045971") +AnnotationAssertion(rdfs:label "positive regulation of juvenile hormone catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of juvenile hormone secretion) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of juvenile hormone.") +AnnotationAssertion( "down regulation of juvenile hormone secretion") +AnnotationAssertion( "down-regulation of juvenile hormone secretion") +AnnotationAssertion( "downregulation of juvenile hormone secretion") +AnnotationAssertion( "inhibition of juvenile hormone secretion") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045972") +AnnotationAssertion(rdfs:label "negative regulation of juvenile hormone secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (positive regulation of juvenile hormone secretion) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of the regulated release of juvenile hormone.") +AnnotationAssertion( "up regulation of juvenile hormone secretion") +AnnotationAssertion( "up-regulation of juvenile hormone secretion") +AnnotationAssertion( "upregulation of juvenile hormone secretion") +AnnotationAssertion( "activation of juvenile hormone secretion") +AnnotationAssertion( "stimulation of juvenile hormone secretion") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045973") +AnnotationAssertion(rdfs:label "positive regulation of juvenile hormone secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of nucleoside metabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleosides.") +AnnotationAssertion( "down regulation of nucleoside metabolic process") +AnnotationAssertion( "down-regulation of nucleoside metabolic process") +AnnotationAssertion( "downregulation of nucleoside metabolic process") +AnnotationAssertion( "negative regulation of nucleoside metabolism") +AnnotationAssertion( "inhibition of nucleoside metabolic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045978") +AnnotationAssertion(rdfs:label "negative regulation of nucleoside metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of nucleoside metabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nucleosides.") +AnnotationAssertion( "positive regulation of nucleoside metabolism") +AnnotationAssertion( "up regulation of nucleoside metabolic process") +AnnotationAssertion( "up-regulation of nucleoside metabolic process") +AnnotationAssertion( "upregulation of nucleoside metabolic process") +AnnotationAssertion( "activation of nucleoside metabolic process") +AnnotationAssertion( "stimulation of nucleoside metabolic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045979") +AnnotationAssertion(rdfs:label "positive regulation of nucleoside metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of nucleotide metabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleotides.") +AnnotationAssertion( "down regulation of nucleotide metabolic process") +AnnotationAssertion( "down-regulation of nucleotide metabolic process") +AnnotationAssertion( "downregulation of nucleotide metabolic process") +AnnotationAssertion( "negative regulation of nucleotide metabolism") +AnnotationAssertion( "inhibition of nucleotide metabolic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045980") +AnnotationAssertion(rdfs:label "negative regulation of nucleotide metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of nucleotide metabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nucleotides.") +AnnotationAssertion( "positive regulation of nucleotide metabolism") +AnnotationAssertion( "up regulation of nucleotide metabolic process") +AnnotationAssertion( "up-regulation of nucleotide metabolic process") +AnnotationAssertion( "upregulation of nucleotide metabolic process") +AnnotationAssertion( "activation of nucleotide metabolic process") +AnnotationAssertion( "stimulation of nucleotide metabolic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045981") +AnnotationAssertion(rdfs:label "positive regulation of nucleotide metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of purine nucleobase metabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving purine nucleobases.") +AnnotationAssertion( "down regulation of purine base metabolic process") +AnnotationAssertion( "down-regulation of purine base metabolic process") +AnnotationAssertion( "downregulation of purine base metabolic process") +AnnotationAssertion(Annotation( "GOC:go_curators") "negative regulation of purine base metabolic process") +AnnotationAssertion( "negative regulation of purine base metabolism") +AnnotationAssertion( "inhibition of purine base metabolic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045982") +AnnotationAssertion(rdfs:label "negative regulation of purine nucleobase metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of purine nucleobase metabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving purine bases.") +AnnotationAssertion( "positive regulation of purine base metabolic process") +AnnotationAssertion( "positive regulation of purine base metabolism") +AnnotationAssertion( "up regulation of purine base metabolic process") +AnnotationAssertion( "up-regulation of purine base metabolic process") +AnnotationAssertion( "upregulation of purine base metabolic process") +AnnotationAssertion( "activation of purine base metabolic process") +AnnotationAssertion( "stimulation of purine base metabolic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045983") +AnnotationAssertion(rdfs:label "positive regulation of purine nucleobase metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of smooth muscle contraction) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle contraction.") +AnnotationAssertion( "down regulation of smooth muscle contraction") +AnnotationAssertion( "down-regulation of smooth muscle contraction") +AnnotationAssertion( "downregulation of smooth muscle contraction") +AnnotationAssertion( "inhibition of smooth muscle contraction") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "smooth muscle relaxation") +AnnotationAssertion( "GO:0045986") +AnnotationAssertion(rdfs:label "negative regulation of smooth muscle contraction") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of smooth muscle contraction) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of smooth muscle contraction.") +AnnotationAssertion( "up regulation of smooth muscle contraction") +AnnotationAssertion( "up-regulation of smooth muscle contraction") +AnnotationAssertion( "upregulation of smooth muscle contraction") +AnnotationAssertion( "activation of smooth muscle contraction") +AnnotationAssertion( "stimulation of smooth muscle contraction") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045987") +AnnotationAssertion(rdfs:label "positive regulation of smooth muscle contraction") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of striated muscle contraction) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle contraction.") +AnnotationAssertion( "down regulation of striated muscle contraction") +AnnotationAssertion( "down-regulation of striated muscle contraction") +AnnotationAssertion( "downregulation of striated muscle contraction") +AnnotationAssertion( "inhibition of striated muscle contraction") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045988") +AnnotationAssertion(rdfs:label "negative regulation of striated muscle contraction") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of striated muscle contraction) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of striated muscle contraction.") +AnnotationAssertion( "up regulation of striated muscle contraction") +AnnotationAssertion( "up-regulation of striated muscle contraction") +AnnotationAssertion( "upregulation of striated muscle contraction") +AnnotationAssertion( "activation of striated muscle contraction") +AnnotationAssertion( "stimulation of striated muscle contraction") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045989") +AnnotationAssertion(rdfs:label "positive regulation of striated muscle contraction") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of embryonic development) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of embryonic development.") +AnnotationAssertion( "down regulation of embryonic development") +AnnotationAssertion( "down-regulation of embryonic development") +AnnotationAssertion( "downregulation of embryonic development") +AnnotationAssertion( "inhibition of embryonic development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045992") +AnnotationAssertion(rdfs:label "negative regulation of embryonic development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of embryonic development) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of embryonic development.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0045995") +AnnotationAssertion(rdfs:label "regulation of embryonic development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (positive regulation of circadian sleep/wake cycle, non-REM sleep) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the duration or quality of non-rapid eye movement (NREM) sleep.") +AnnotationAssertion( "positive regulation of non-REM sleep") +AnnotationAssertion( "up regulation of circadian sleep/wake cycle, non-REM sleep") +AnnotationAssertion( "up-regulation of circadian sleep/wake cycle, non-REM sleep") +AnnotationAssertion( "upregulation of circadian sleep/wake cycle, non-REM sleep") +AnnotationAssertion( "activation of circadian sleep/wake cycle, non-REM sleep") +AnnotationAssertion( "stimulation of circadian sleep/wake cycle, non-REM sleep") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0046010") +AnnotationAssertion(rdfs:label "positive regulation of circadian sleep/wake cycle, non-REM sleep") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of T cell homeostatic proliferation) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of resting T cell proliferation.") +AnnotationAssertion( "regulation of T lymphocyte homeostatic proliferation") +AnnotationAssertion( "regulation of T-cell homeostatic proliferation") +AnnotationAssertion( "regulation of T-lymphocyte homeostatic proliferation") +AnnotationAssertion( "regulation of resting T cell proliferation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0046013") +AnnotationAssertion(rdfs:label "regulation of T cell homeostatic proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of T cell homeostatic proliferation) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents or reduces the rate or extent of resting T cell proliferation.") +AnnotationAssertion( "down regulation of T cell homeostatic proliferation") +AnnotationAssertion( "down-regulation of T cell homeostatic proliferation") +AnnotationAssertion( "downregulation of T cell homeostatic proliferation") +AnnotationAssertion( "negative regulation of T lymphocyte homeostatic proliferation") +AnnotationAssertion( "negative regulation of T-cell homeostatic proliferation") +AnnotationAssertion( "negative regulation of T-lymphocyte homeostatic proliferation") +AnnotationAssertion( "negative regulation of resting T cell proliferation") +AnnotationAssertion( "inhibition of T cell homeostatic proliferation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0046014") +AnnotationAssertion(rdfs:label "negative regulation of T cell homeostatic proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (ADP metabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways involving ADP, adenosine 5'-diphosphate.") +AnnotationAssertion( "ADP metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0046031") +AnnotationAssertion(rdfs:label "ADP metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (ADP catabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways resulting in the breakdown of ADP, adenosine 5'-diphosphate.") +AnnotationAssertion( "ADP breakdown") +AnnotationAssertion( "ADP catabolism") +AnnotationAssertion( "ADP degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0046032") +AnnotationAssertion(rdfs:label "ADP catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (ATP metabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways involving ATP, adenosine triphosphate, a universally important coenzyme and enzyme regulator.") +AnnotationAssertion( "ATP metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0046034") +AnnotationAssertion(rdfs:label "ATP metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (adenine metabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways involving adenine, 6-aminopurine, one of the five main bases found in nucleic acids and a component of numerous important derivatives of its corresponding ribonucleoside, adenosine.") +AnnotationAssertion( "adenine metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0046083") +AnnotationAssertion(rdfs:label "adenine metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (adenine biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways resulting in the formation of adenine, 6-aminopurine, one of the five main bases found in nucleic acids and a component of numerous important derivatives of its corresponding ribonucleoside, adenosine.") +AnnotationAssertion( "adenine anabolism") +AnnotationAssertion( "adenine biosynthesis") +AnnotationAssertion( "adenine formation") +AnnotationAssertion( "adenine synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0046084") +AnnotationAssertion(rdfs:label "adenine biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (adenosine metabolic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways involving adenosine, adenine riboside, a ribonucleoside found widely distributed in cells of every type as the free nucleoside and in combination in nucleic acids and various nucleoside coenzymes.") +AnnotationAssertion( "adenosine metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0046085") +AnnotationAssertion(rdfs:label "adenosine metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (adenosine biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:go_curators") "The chemical reactions and pathways resulting in the formation of adenosine, adenine riboside, a ribonucleoside found widely distributed in cells of every type as the free nucleoside and in combination in nucleic acids and various nucleoside coenzymes.") +AnnotationAssertion( "adenosine anabolism") +AnnotationAssertion( "adenosine biosynthesis") +AnnotationAssertion( "adenosine formation") +AnnotationAssertion( "adenosine synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0046086") +AnnotationAssertion(rdfs:label "adenosine biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (nucleobase biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways resulting in the formation of a nucleobase, a nitrogenous base that is a constituent of a nucleic acid.") +AnnotationAssertion( "nucleobase anabolism") +AnnotationAssertion( "nucleobase biosynthesis") +AnnotationAssertion( "nucleobase formation") +AnnotationAssertion( "nucleobase synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0046112") +AnnotationAssertion(rdfs:label "nucleobase biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (nucleobase catabolic process) + +AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways resulting in the breakdown of a nucleobase, a nitrogenous base that is a constituent of a nucleic acid.") +AnnotationAssertion( "nucleobase breakdown") +AnnotationAssertion( "nucleobase catabolism") +AnnotationAssertion( "nucleobase degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0046113") +AnnotationAssertion(rdfs:label "nucleobase catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (purine ribonucleoside metabolic process) + +AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways involving any ribonucleoside, a nucleoside in which purine base is linked to a ribose (beta-D-ribofuranose) molecule.") +AnnotationAssertion( "purine ribonucleoside metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0046128") +AnnotationAssertion(rdfs:label "purine ribonucleoside metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (purine ribonucleoside biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways resulting in the formation of any purine ribonucleoside, a nucleoside in which purine base is linked to a ribose (beta-D-ribofuranose) molecule.") +AnnotationAssertion( "purine ribonucleoside anabolism") +AnnotationAssertion( "purine ribonucleoside biosynthesis") +AnnotationAssertion( "purine ribonucleoside formation") +AnnotationAssertion( "purine ribonucleoside synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0046129") +AnnotationAssertion(rdfs:label "purine ribonucleoside biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (purine ribonucleoside catabolic process) + +AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways resulting in the breakdown of any purine ribonucleoside, a nucleoside in which purine base is linked to a ribose (beta-D-ribofuranose) molecule.") +AnnotationAssertion( "purine ribonucleoside breakdown") +AnnotationAssertion( "purine ribonucleoside catabolism") +AnnotationAssertion( "purine ribonucleoside degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0046130") +AnnotationAssertion(rdfs:label "purine ribonucleoside catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (pigment biosynthetic process) + +AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of a pigment, any general or particular coloring matter in living organisms, e.g. melanin.") +AnnotationAssertion( "pigment anabolism") +AnnotationAssertion( "pigment biosynthesis") +AnnotationAssertion( "pigment formation") +AnnotationAssertion( "pigment synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0046148") +AnnotationAssertion(rdfs:label "pigment biosynthetic process") +SubClassOf( ) + +# Class: (alcohol catabolic process) + +AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways resulting in the breakdown of alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom.") +AnnotationAssertion( "alcohol breakdown") +AnnotationAssertion( "alcohol catabolism") +AnnotationAssertion( "alcohol degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0046164") +AnnotationAssertion(rdfs:label "alcohol catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (alcohol biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways resulting in the formation of alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom.") +AnnotationAssertion( "alcohol anabolism") +AnnotationAssertion( "alcohol biosynthesis") +AnnotationAssertion( "alcohol formation") +AnnotationAssertion( "alcohol synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0046165") +AnnotationAssertion(rdfs:label "alcohol biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + # Class: (aldehyde biosynthetic process) AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways resulting in the formation of aldehydes, any organic compound with the formula R-CH=O.") @@ -37242,11 +87096,170 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0046184") AnnotationAssertion(rdfs:label "aldehyde biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) +# Class: (aldehyde catabolic process) + +AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways resulting in the breakdown of aldehydes, any organic compound with the formula R-CH=O.") +AnnotationAssertion( "aldehyde breakdown") +AnnotationAssertion( "aldehyde catabolism") +AnnotationAssertion( "aldehyde degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0046185") +AnnotationAssertion(rdfs:label "aldehyde catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (phenol-containing compound biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways resulting in the formation of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring.") +AnnotationAssertion( "phenol-containing compound anabolism") +AnnotationAssertion( "phenol-containing compound biosynthesis") +AnnotationAssertion( "phenol-containing compound formation") +AnnotationAssertion( "phenol-containing compound synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0046189") +AnnotationAssertion(rdfs:label "phenol-containing compound biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (indolalkylamine biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:curators") "The chemical reactions and pathways resulting in the formation of indolalkylamines, indole or indole derivatives containing a primary, secondary, or tertiary amine group.") +AnnotationAssertion( "indolalkylamine anabolism") +AnnotationAssertion( "indolalkylamine biosynthesis") +AnnotationAssertion( "indolalkylamine formation") +AnnotationAssertion( "indolalkylamine synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0046219") +AnnotationAssertion(rdfs:label "indolalkylamine biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (terpene biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways resulting in the formation of terpenes, any of a large group of hydrocarbons made up of isoprene units.") +AnnotationAssertion( "terpene anabolism") +AnnotationAssertion( "terpene biosynthesis") +AnnotationAssertion( "terpene formation") +AnnotationAssertion( "terpene synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0046246") +AnnotationAssertion(rdfs:label "terpene biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (terpene catabolic process) + +AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways resulting in the breakdown of terpenes, any of a large group of hydrocarbons made up of isoprene units.") +AnnotationAssertion( "terpene breakdown") +AnnotationAssertion( "terpene catabolism") +AnnotationAssertion( "terpene degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0046247") +AnnotationAssertion(rdfs:label "terpene catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (amino sugar catabolic process) + +AnnotationAssertion(Annotation( "GOC:curators") "The chemical reactions and pathways resulting in the breakdown of any amino sugar, sugars containing an amino group in place of a hydroxyl group.") +AnnotationAssertion( "amino sugar breakdown") +AnnotationAssertion( "amino sugar catabolism") +AnnotationAssertion( "amino sugar degradation") +AnnotationAssertion( "aminosaccharide catabolic process") +AnnotationAssertion( "aminosaccharide catabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0046348") +AnnotationAssertion(rdfs:label "amino sugar catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (amino sugar biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:curators") "The chemical reactions and pathways resulting in the formation of any amino sugar, sugars containing an amino group in place of a hydroxyl group.") +AnnotationAssertion( "amino sugar anabolism") +AnnotationAssertion( "amino sugar biosynthesis") +AnnotationAssertion( "amino sugar formation") +AnnotationAssertion( "amino sugar synthesis") +AnnotationAssertion( "aminosaccharide biosynthesis") +AnnotationAssertion( "aminosaccharide biosynthetic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0046349") +AnnotationAssertion(rdfs:label "amino sugar biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (butyrate biosynthetic process) + +AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of butyrate, the anion of butyric acid.") +AnnotationAssertion( "GO:0043439") +AnnotationAssertion( "butanoic acid anabolism") +AnnotationAssertion( "butanoic acid biosynthesis") +AnnotationAssertion( "butanoic acid biosynthetic process") +AnnotationAssertion( "butanoic acid formation") +AnnotationAssertion( "butanoic acid synthesis") +AnnotationAssertion( "butyrate anabolism") +AnnotationAssertion( "butyrate biosynthesis") +AnnotationAssertion( "butyrate formation") +AnnotationAssertion( "butyrate synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0046358") +AnnotationAssertion(rdfs:label "butyrate biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (butyrate catabolic process) + +AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of butyrate, the anion of butyric acid.") +AnnotationAssertion( "GO:0043440") +AnnotationAssertion( "butanoic acid breakdown") +AnnotationAssertion( "butanoic acid catabolic process") +AnnotationAssertion( "butanoic acid catabolism") +AnnotationAssertion( "butanoic acid degradation") +AnnotationAssertion( "butyrate breakdown") +AnnotationAssertion( "butyrate catabolism") +AnnotationAssertion( "butyrate degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0046359") +AnnotationAssertion(rdfs:label "butyrate catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (monosaccharide biosynthetic process) + +AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of monosaccharides, polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms.") +AnnotationAssertion( "monosaccharide anabolism") +AnnotationAssertion( "monosaccharide biosynthesis") +AnnotationAssertion( "monosaccharide formation") +AnnotationAssertion( "monosaccharide synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0046364") +AnnotationAssertion(rdfs:label "monosaccharide biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (monosaccharide catabolic process) + +AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of monosaccharides, polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms.") +AnnotationAssertion( "monosaccharide breakdown") +AnnotationAssertion( "monosaccharide catabolism") +AnnotationAssertion( "monosaccharide degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0046365") +AnnotationAssertion(rdfs:label "monosaccharide catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (ribose phosphate biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways resulting in the formation of ribose phosphate, any phosphorylated ribose sugar.") +AnnotationAssertion( "ribose phosphate anabolism") +AnnotationAssertion( "ribose phosphate biosynthesis") +AnnotationAssertion( "ribose phosphate formation") +AnnotationAssertion( "ribose phosphate synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0046390") +AnnotationAssertion(rdfs:label "ribose phosphate biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (carboxylic acid biosynthetic process) AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the formation of carboxylic acids, any organic acid containing one or more carboxyl (-COOH) groups.") @@ -37257,9 +87270,124 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0046394") AnnotationAssertion(rdfs:label "carboxylic acid biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) +# Class: (carboxylic acid catabolic process) + +AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of carboxylic acids, any organic acid containing one or more carboxyl (-COOH) groups.") +AnnotationAssertion( "carboxylic acid breakdown") +AnnotationAssertion( "carboxylic acid catabolism") +AnnotationAssertion( "carboxylic acid degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0046395") +AnnotationAssertion(rdfs:label "carboxylic acid catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (D-amino acid metabolic process) + +AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:jsg") "The chemical reactions and pathways involving D-amino acids, the D-enantiomers of amino acids.") +AnnotationAssertion( "D-amino acid metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0046416") +AnnotationAssertion(rdfs:label "D-amino acid metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (organophosphate catabolic process) + +AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways resulting in the breakdown of organophosphates, any phosphate-containing organic compound.") +AnnotationAssertion( "organophosphate breakdown") +AnnotationAssertion( "organophosphate catabolism") +AnnotationAssertion( "organophosphate degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0046434") +AnnotationAssertion(rdfs:label "organophosphate catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (D-amino acid biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:jsg") "The chemical reactions and pathways resulting in the formation of D-amino acids, the D-enantiomers of amino acids.") +AnnotationAssertion( "D-amino acid anabolism") +AnnotationAssertion( "D-amino acid biosynthesis") +AnnotationAssertion( "D-amino acid formation") +AnnotationAssertion( "D-amino acid synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0046437") +AnnotationAssertion(rdfs:label "D-amino acid biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (short-chain fatty acid metabolic process) + +AnnotationAssertion(Annotation( "Wikipedia:Fatty_acid_metabolism") "The chemical reactions and pathways involving a fatty acid with an aliphatic tail of less than 6 carbons.") +AnnotationAssertion( "short-chain fatty acid metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0046459") +AnnotationAssertion(rdfs:label "short-chain fatty acid metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (membrane lipid catabolic process) + +AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways resulting in the breakdown of membrane lipids, any lipid found in or associated with a biological membrane.") +AnnotationAssertion(Annotation( "GOC:tb") "membrane lipid peroxidation") +AnnotationAssertion( "membrane lipid breakdown") +AnnotationAssertion( "membrane lipid catabolism") +AnnotationAssertion( "membrane lipid degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0046466") +AnnotationAssertion(rdfs:label "membrane lipid catabolic process") +SubClassOf( ) +SubClassOf( ) + +# Class: (membrane lipid biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways resulting in the formation of membrane lipids, any lipid found in or associated with a biological membrane.") +AnnotationAssertion( "membrane lipid anabolism") +AnnotationAssertion( "membrane lipid biosynthesis") +AnnotationAssertion( "membrane lipid formation") +AnnotationAssertion( "membrane lipid synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0046467") +AnnotationAssertion(rdfs:label "membrane lipid biosynthetic process") +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (glycosylceramide biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways resulting in the formation of glycosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of a monosaccharide (or derivative) by a ceramide group.") +AnnotationAssertion( "glycosylceramide anabolism") +AnnotationAssertion( "glycosylceramide biosynthesis") +AnnotationAssertion( "glycosylceramide formation") +AnnotationAssertion( "glycosylceramide synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0046476") +AnnotationAssertion(rdfs:label "glycosylceramide biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (glycosylceramide catabolic process) + +AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways resulting in the breakdown of glycosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of a monosaccharide (or derivative) by a ceramide group.") +AnnotationAssertion( "glycosylceramide breakdown") +AnnotationAssertion( "glycosylceramide catabolism") +AnnotationAssertion( "glycosylceramide degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0046477") +AnnotationAssertion(rdfs:label "glycosylceramide catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (glycosphingolipid catabolic process) + +AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways resulting in the breakdown of glycosphingolipid, a compound with residues of sphingoid and at least one monosaccharide.") +AnnotationAssertion( "glycosphingolipid breakdown") +AnnotationAssertion( "glycosphingolipid catabolism") +AnnotationAssertion( "glycosphingolipid degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0046479") +AnnotationAssertion(rdfs:label "glycosphingolipid catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (heterocycle metabolic process) AnnotationAssertion(Annotation( "ISBN:0198506732") "The chemical reactions and pathways involving heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings).") @@ -37268,8 +87396,92 @@ AnnotationAssertion( "GO:0046483") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "heterocycle metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (ceramide biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways resulting in the formation of ceramides, any N-acylated sphingoid.") +AnnotationAssertion( "ceramide anabolism") +AnnotationAssertion( "ceramide biosynthesis") +AnnotationAssertion( "ceramide formation") +AnnotationAssertion( "ceramide synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0046513") +AnnotationAssertion(rdfs:label "ceramide biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (ceramide catabolic process) + +AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways resulting in the breakdown of ceramides, any N-acetylated sphingoid.") +AnnotationAssertion( "ceramide breakdown") +AnnotationAssertion( "ceramide catabolism") +AnnotationAssertion( "ceramide degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0046514") +AnnotationAssertion(rdfs:label "ceramide catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (photoreceptor cell differentiation) + +AnnotationAssertion(Annotation( "GOC:ai") Annotation( "ISBN:0198506732") "The specialization of organization of a photoreceptor, a cell that responds to incident electromagnetic radiation, particularly visible light. An example of this process is found in Drosophila melanogaster.") +AnnotationAssertion( "GO:0007467") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0046530") +AnnotationAssertion(rdfs:label "photoreceptor cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of photoreceptor cell differentiation) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of photoreceptor cell differentiation. An example of this process is found in Drosophila melanogaster.") +AnnotationAssertion( "GO:0045673") +AnnotationAssertion( "regulation of photoreceptor differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0046532") +AnnotationAssertion(rdfs:label "regulation of photoreceptor cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of photoreceptor cell differentiation) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of photoreceptor cell differentiation. An example of this process is found in Drosophila melanogaster.") +AnnotationAssertion( "GO:0045674") +AnnotationAssertion( "down regulation of photoreceptor cell differentiation") +AnnotationAssertion( "down regulation of photoreceptor differentiation") +AnnotationAssertion( "down-regulation of photoreceptor cell differentiation") +AnnotationAssertion( "down-regulation of photoreceptor differentiation") +AnnotationAssertion( "downregulation of photoreceptor cell differentiation") +AnnotationAssertion( "downregulation of photoreceptor differentiation") +AnnotationAssertion( "negative regulation of photoreceptor differentiation") +AnnotationAssertion( "inhibition of photoreceptor cell differentiation") +AnnotationAssertion( "inhibition of photoreceptor differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0046533") +AnnotationAssertion(rdfs:label "negative regulation of photoreceptor cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (positive regulation of photoreceptor cell differentiation) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates or increases the frequency, rate or extent of photoreceptor cell differentiation. An example of this process is found in Drosophila melanogaster.") +AnnotationAssertion( "GO:0045675") +AnnotationAssertion( "positive regulation of photoreceptor differentiation") +AnnotationAssertion( "up regulation of photoreceptor cell differentiation") +AnnotationAssertion( "up regulation of photoreceptor differentiation") +AnnotationAssertion( "up-regulation of photoreceptor cell differentiation") +AnnotationAssertion( "up-regulation of photoreceptor differentiation") +AnnotationAssertion( "upregulation of photoreceptor cell differentiation") +AnnotationAssertion( "upregulation of photoreceptor differentiation") +AnnotationAssertion( "activation of photoreceptor cell differentiation") +AnnotationAssertion( "activation of photoreceptor differentiation") +AnnotationAssertion( "stimulation of photoreceptor cell differentiation") +AnnotationAssertion( "stimulation of photoreceptor differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0046534") +AnnotationAssertion(rdfs:label "positive regulation of photoreceptor cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + # Class: (saliva secretion) AnnotationAssertion(Annotation( "GOC:curators") Annotation( "UBERON:0001836") "The regulated release of saliva from the salivary glands. In man, the saliva is a turbid and slightly viscous fluid, generally of an alkaline reaction, and is secreted by the parotid, submaxillary, and sublingual glands. In the mouth the saliva is mixed with the secretion from the buccal glands. In man and many animals, saliva is an important digestive fluid on account of the presence of the peculiar enzyme, ptyalin.") @@ -37291,12 +87503,123 @@ AnnotationAssertion(rdfs:label "deve SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (development of primary male sexual characteristics) + +AnnotationAssertion(Annotation( "GOC:ai") "The process whose specific outcome is the progression of the primary male sexual characteristics over time, from their formation to the mature structures. The primary male sexual characteristics are the testes, and they develop in response to sex hormone secretion.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0046546") +AnnotationAssertion(rdfs:label "development of primary male sexual characteristics") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (retinal rod cell development) + +AnnotationAssertion(Annotation( "ISBN:0198506732") "Development of a rod cell, one of the sensory cells in the eye that reacts to the presence of light. Rod cells contain the photopigment rhodopsin or porphyropsin and are responsible for vision in dim light.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0046548") +AnnotationAssertion(rdfs:label "retinal rod cell development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (retinal cone cell development) + +AnnotationAssertion(Annotation( "ISBN:0198506732") "Development of a cone cell, one of the sensory cells in the eye that reacts to the presence of light. Cone cells contain the photopigment iodopsin or cyanopsin and are responsible for photopic (daylight) vision.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0046549") +AnnotationAssertion(rdfs:label "retinal cone cell development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (regulation of organ growth) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:tb") "Any process that modulates the frequency, rate or extent of growth of an organ of an organism.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0046620") +AnnotationAssertion(rdfs:label "regulation of organ growth") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of organ growth) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:tb") "Any process that stops, prevents, or reduces the frequency, rate or extent of growth of an organ of an organism.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0046621") +AnnotationAssertion(rdfs:label "negative regulation of organ growth") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of organ growth) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:tb") "Any process that activates or increases the frequency, rate or extent of growth of an organ of an organism.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0046622") +AnnotationAssertion(rdfs:label "positive regulation of organ growth") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (sphingolipid transporter activity) + +AnnotationAssertion(Annotation( "GOC:ai") Annotation( "ISBN:0198506732") "Enables the directed movement of sphingolipids into, out of or within a cell, or between cells. Sphingolipids are a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).") +AnnotationAssertion(Annotation(rdfs:label "SPNS2 transports S1P from cytosol to extracellular region") "Reactome:R-HSA-9695890") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0046624") +AnnotationAssertion(rdfs:label "sphingolipid transporter activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (sphingolipid binding) + +AnnotationAssertion(Annotation( "ISBN:0198506732") "Binding to a sphingolipid, a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0046625") +AnnotationAssertion(rdfs:label "sphingolipid binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of insulin receptor signaling pathway) + +AnnotationAssertion(Annotation( "GOC:bf") "Any process that modulates the frequency, rate or extent of insulin receptor signaling.") +AnnotationAssertion( "regulation of insulin receptor signalling pathway") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0046626") +AnnotationAssertion(rdfs:label "regulation of insulin receptor signaling pathway") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectAllValuesFrom( )) + +# Class: (negative regulation of insulin receptor signaling pathway) + +AnnotationAssertion(Annotation( "GOC:bf") "Any process that stops, prevents, or reduces the frequency, rate or extent of insulin receptor signaling.") +AnnotationAssertion( "down regulation of insulin receptor signaling pathway") +AnnotationAssertion( "down-regulation of insulin receptor signaling pathway") +AnnotationAssertion( "downregulation of insulin receptor signaling pathway") +AnnotationAssertion( "negative regulation of insulin receptor signalling pathway") +AnnotationAssertion( "inhibition of insulin receptor signaling pathway") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0046627") +AnnotationAssertion(rdfs:label "negative regulation of insulin receptor signaling pathway") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (positive regulation of insulin receptor signaling pathway) + +AnnotationAssertion(Annotation( "GOC:bf") "Any process that increases the frequency, rate or extent of insulin receptor signaling.") +AnnotationAssertion( "positive regulation of insulin receptor signalling pathway") +AnnotationAssertion( "up regulation of insulin receptor signaling pathway") +AnnotationAssertion( "up-regulation of insulin receptor signaling pathway") +AnnotationAssertion( "upregulation of insulin receptor signaling pathway") +AnnotationAssertion( "activation of insulin receptor signaling pathway") +AnnotationAssertion( "stimulation of insulin receptor signaling pathway") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0046628") +AnnotationAssertion(rdfs:label "positive regulation of insulin receptor signaling pathway") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + # Class: (lymphocyte activation) AnnotationAssertion(Annotation( "GOC:mgi_curators") Annotation( "ISBN:0781735149") "A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor.") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0046649") AnnotationAssertion(rdfs:label "lymphocyte activation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) # Class: (lymphocyte proliferation) @@ -37305,6 +87628,7 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:0046651") AnnotationAssertion(rdfs:label "lymphocyte proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) @@ -37317,6 +87641,148 @@ AnnotationAssertion(rdfs:label "fema SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (male sex differentiation) + +AnnotationAssertion(Annotation( "GOC:bf") "The establishment of the sex of a male organism by physical differentiation.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0046661") +AnnotationAssertion(rdfs:label "male sex differentiation") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (retinal cell programmed cell death) + +AnnotationAssertion(Annotation( "GOC:bf") "Programmed cell death that occurs in the developing retina.") +AnnotationAssertion( "programmed cell death, retina cells") +AnnotationAssertion( "programmed cell death, retinal cells") +AnnotationAssertion( "retina cell programmed cell death") +AnnotationAssertion( "retina programmed cell death") +AnnotationAssertion( "retinal programmed cell death") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0046666") +AnnotationAssertion(rdfs:label "retinal cell programmed cell death") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (compound eye retinal cell programmed cell death) + +AnnotationAssertion(Annotation( "PMID:12006672") "Programmed cell death that occurs in the retina to remove excess cells between ommatidia, thus resulting in a hexagonal lattice, precise with respect to cell number and position surrounding each ommatidium.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0046667") +AnnotationAssertion(rdfs:label "compound eye retinal cell programmed cell death") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (regulation of retinal cell programmed cell death) + +AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:tb") "Any process that modulates the frequency, rate or extent of programmed cell death that occurs in the retina.") +AnnotationAssertion(Annotation( "GOC:tb") "regulation of retinal programmed cell death") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0046668") +AnnotationAssertion(rdfs:label "regulation of retinal cell programmed cell death") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of compound eye retinal cell programmed cell death) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of programmed cell death that occurs in the compound eye retina.") +AnnotationAssertion( "regulation of retinal cell programmed cell death") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0046669") +AnnotationAssertion(rdfs:label "regulation of compound eye retinal cell programmed cell death") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of retinal cell programmed cell death) + +AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:tb") "Any process that activates or increases the frequency, rate or extent of programmed cell death that occurs in the retina.") +AnnotationAssertion(Annotation( "GOC:tb") "positive regulation of retinal programmed cell death") +AnnotationAssertion( "up regulation of retinal programmed cell death") +AnnotationAssertion( "up-regulation of retinal programmed cell death") +AnnotationAssertion( "upregulation of retinal programmed cell death") +AnnotationAssertion( "activation of retinal programmed cell death") +AnnotationAssertion( "stimulation of retinal programmed cell death") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0046670") +AnnotationAssertion(rdfs:label "positive regulation of retinal cell programmed cell death") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of retinal cell programmed cell death) + +AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:tb") "Any process that stops, prevents, or reduces the frequency, rate or extent of programmed cell death that occurs in the retina.") +AnnotationAssertion( "down regulation of retinal programmed cell death") +AnnotationAssertion( "down-regulation of retinal programmed cell death") +AnnotationAssertion( "downregulation of retinal programmed cell death") +AnnotationAssertion(Annotation( "GOC:tb") "negative regulation of retinal programmed cell death") +AnnotationAssertion( "inhibition of retinal programmed cell death") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0046671") +AnnotationAssertion(rdfs:label "negative regulation of retinal cell programmed cell death") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of compound eye retinal cell programmed cell death) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of programmed cell death that occurs in the compound eye retina.") +AnnotationAssertion( "activation of retinal cell programmed cell death") +AnnotationAssertion( "positive regulation of retinal cell programmed cell death") +AnnotationAssertion( "stimulation of retinal cell programmed cell death") +AnnotationAssertion( "up regulation of retinal cell programmed cell death") +AnnotationAssertion( "up-regulation of retinal cell programmed cell death") +AnnotationAssertion( "upregulation of retinal cell programmed cell death") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0046672") +AnnotationAssertion(rdfs:label "positive regulation of compound eye retinal cell programmed cell death") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of compound eye retinal cell programmed cell death) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of programmed cell death that occurs in the compound eye retina.") +AnnotationAssertion( "down regulation of retinal cell programmed cell death") +AnnotationAssertion( "down-regulation of retinal cell programmed cell death") +AnnotationAssertion( "downregulation of retinal cell programmed cell death") +AnnotationAssertion( "inhibition of retinal cell programmed cell death") +AnnotationAssertion( "negative regulation of retina cell programmed cell death") +AnnotationAssertion( "negative regulation of retinal cell programmed cell death") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0046673") +AnnotationAssertion(rdfs:label "negative regulation of compound eye retinal cell programmed cell death") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of insulin secretion) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of insulin.") +AnnotationAssertion( "down regulation of insulin secretion") +AnnotationAssertion( "down-regulation of insulin secretion") +AnnotationAssertion( "downregulation of insulin secretion") +AnnotationAssertion( "inhibition of insulin secretion") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0046676") +AnnotationAssertion(rdfs:label "negative regulation of insulin secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (response to carbamate) + +AnnotationAssertion(Annotation( "ISBN:0721662544") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbamate stimulus. Carbamates are a group of insecticides and parasiticides that act by inhibiting cholinesterase.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "carbamate resistance") +AnnotationAssertion( "carbamate susceptibility/resistance") +AnnotationAssertion( "GO:0046681") +AnnotationAssertion(rdfs:label "response to carbamate") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (response to organophosphorus) + +AnnotationAssertion(Annotation( "ISBN:0721662544") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organophosphorus stimulus. Organophosphorus is a compound containing phosphorus bound to an organic molecule; several organophosphorus compounds are used as insecticides, and they are highly toxic cholinesterase inhibitors.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "organophosphorus resistance") +AnnotationAssertion( "organophosphorus susceptibility/resistance") +AnnotationAssertion( "GO:0046683") +AnnotationAssertion(rdfs:label "response to organophosphorus") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (sperm competition) AnnotationAssertion(Annotation( "PMID:10885514") "Any process that contributes to the success of sperm fertilization in multiply-mated females.") @@ -37329,6 +87795,33 @@ SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (heterocycle catabolic process) + +AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways resulting in the breakdown of heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings).") +AnnotationAssertion( "heterocycle breakdown") +AnnotationAssertion( "heterocycle catabolism") +AnnotationAssertion( "heterocycle degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0046700") +AnnotationAssertion(rdfs:label "heterocycle catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (muscle cell cellular homeostasis) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "PMID:3091429") Annotation( "PMID:7781901") "The cellular homeostatic process that preserves a muscle cell in a stable functional or structural state.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/24218"^^xsd:anyURI) +AnnotationAssertion( ) +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "muscle fiber maintenance") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") "muscle homeostasis") +AnnotationAssertion( "GO:0046716") +AnnotationAssertion(rdfs:label "muscle cell cellular homeostasis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses( ObjectSomeValuesFrom( )) + # Class: (acid secretion) AnnotationAssertion(Annotation( "GOC:ai") "The controlled release of acid by a cell or a tissue.") @@ -37556,6 +88049,7 @@ SubClassOf( (regulation of bone remodeling) AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of bone remodeling, the processes of bone formation and resorption that combine to maintain skeletal integrity.") +AnnotationAssertion( "regulation of bone remodelling") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0046850") AnnotationAssertion(rdfs:label "regulation of bone remodeling") @@ -37567,6 +88061,7 @@ AnnotationAssertion(Annotation( "down regulation of bone remodeling") AnnotationAssertion( "down-regulation of bone remodeling") AnnotationAssertion( "downregulation of bone remodeling") +AnnotationAssertion( "negative regulation of bone remodelling") AnnotationAssertion( "inhibition of bone remodeling") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0046851") @@ -37576,6 +88071,7 @@ EquivalentClasses( ObjectIntersection # Class: (positive regulation of bone remodeling) AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of bone remodeling.") +AnnotationAssertion( "positive regulation of bone remodelling") AnnotationAssertion( "up regulation of bone remodeling") AnnotationAssertion( "up-regulation of bone remodeling") AnnotationAssertion( "upregulation of bone remodeling") @@ -37690,11 +88186,115 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:0046883") AnnotationAssertion(rdfs:label "regulation of hormone secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) +# Class: (regulation of hormone biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hormones.") +AnnotationAssertion( "regulation of hormone anabolism") +AnnotationAssertion( "regulation of hormone biosynthesis") +AnnotationAssertion( "regulation of hormone formation") +AnnotationAssertion( "regulation of hormone synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0046885") +AnnotationAssertion(rdfs:label "regulation of hormone biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of hormone biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hormones.") +AnnotationAssertion( "positive regulation of hormone anabolism") +AnnotationAssertion( "positive regulation of hormone biosynthesis") +AnnotationAssertion( "positive regulation of hormone formation") +AnnotationAssertion( "positive regulation of hormone synthesis") +AnnotationAssertion( "up regulation of hormone biosynthetic process") +AnnotationAssertion( "up-regulation of hormone biosynthetic process") +AnnotationAssertion( "upregulation of hormone biosynthetic process") +AnnotationAssertion( "activation of hormone biosynthetic process") +AnnotationAssertion( "stimulation of hormone biosynthetic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0046886") +AnnotationAssertion(rdfs:label "positive regulation of hormone biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of hormone secretion) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of the regulated release of a hormone from a cell.") +AnnotationAssertion( "up regulation of hormone secretion") +AnnotationAssertion( "up-regulation of hormone secretion") +AnnotationAssertion( "upregulation of hormone secretion") +AnnotationAssertion( "activation of hormone secretion") +AnnotationAssertion( "stimulation of hormone secretion") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0046887") +AnnotationAssertion(rdfs:label "positive regulation of hormone secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of hormone secretion) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a hormone from a cell.") +AnnotationAssertion( "down regulation of hormone secretion") +AnnotationAssertion( "down-regulation of hormone secretion") +AnnotationAssertion( "downregulation of hormone secretion") +AnnotationAssertion( "inhibition of hormone secretion") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0046888") +AnnotationAssertion(rdfs:label "negative regulation of hormone secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of lipid biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids.") +AnnotationAssertion( "positive regulation of lipid anabolism") +AnnotationAssertion( "positive regulation of lipid biosynthesis") +AnnotationAssertion( "positive regulation of lipid formation") +AnnotationAssertion( "positive regulation of lipid synthesis") +AnnotationAssertion(Annotation( "GOC:sl") "positive regulation of lipogenesis") +AnnotationAssertion( "up regulation of lipid biosynthetic process") +AnnotationAssertion( "up-regulation of lipid biosynthetic process") +AnnotationAssertion( "upregulation of lipid biosynthetic process") +AnnotationAssertion( "activation of lipid biosynthetic process") +AnnotationAssertion( "stimulation of lipid biosynthetic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0046889") +AnnotationAssertion(rdfs:label "positive regulation of lipid biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of lipid biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids.") +AnnotationAssertion( "regulation of lipid anabolism") +AnnotationAssertion( "regulation of lipid biosynthesis") +AnnotationAssertion( "regulation of lipid formation") +AnnotationAssertion( "regulation of lipid synthesis") +AnnotationAssertion(Annotation( "GOC:sl") "regulation of lipogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0046890") +AnnotationAssertion(rdfs:label "regulation of lipid biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + # Class: (secretion) AnnotationAssertion(Annotation( "GOC:ai") "The controlled release of a substance by a cell or a tissue.") @@ -37704,12 +88304,341 @@ AnnotationAssertion( "secretion") SubClassOf( ) +# Class: (tetrapyrrole binding) + +AnnotationAssertion(Annotation( "GOC:curators") Annotation( "ISBN:0198506732") "Binding to a tetrapyrrole, a compound containing four pyrrole nuclei variously substituted and linked to each other through carbons at the alpha position.") +AnnotationAssertion( "porphyrin binding") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0046906") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "tetrapyrrole binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (intracellular transport) + +AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of substances within a cell.") +AnnotationAssertion( "jl") +AnnotationAssertion( "2013-12-18T14:04:50Z") +AnnotationAssertion( "GO:1902582") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "single organism intracellular transport") +AnnotationAssertion( "single-organism intracellular transport") +AnnotationAssertion( "GO:0046907") +AnnotationAssertion(rdfs:label "intracellular transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (transition metal ion binding) + +AnnotationAssertion(Annotation( "ISBN:0198506732") "Binding to a transition metal ions; a transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver.") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0046914") +AnnotationAssertion(rdfs:label "transition metal ion binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (transition metal ion transmembrane transporter activity) + +AnnotationAssertion(Annotation( "ISBN:0198506732") "Enables the transfer of transition metal ions from one side of a membrane to the other. A transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver.") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0046915") +AnnotationAssertion(rdfs:label "transition metal ion transmembrane transporter activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (regulation of neurotransmitter secretion) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of the regulated release of a neurotransmitter from a cell.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0046928") +AnnotationAssertion(rdfs:label "regulation of neurotransmitter secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (negative regulation of neurotransmitter secretion) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a neurotransmitter.") +AnnotationAssertion( "down regulation of neurotransmitter secretion") +AnnotationAssertion( "down-regulation of neurotransmitter secretion") +AnnotationAssertion( "downregulation of neurotransmitter secretion") +AnnotationAssertion( "conotoxin activity") +AnnotationAssertion( "inhibition of neurotransmitter secretion") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0046929") +AnnotationAssertion(rdfs:label "negative regulation of neurotransmitter secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (carboxylic acid transport) AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of carboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carboxylic acids are organic acids containing one or more carboxyl (COOH) groups or anions (COO-).") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0046942") AnnotationAssertion(rdfs:label "carboxylic acid transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (carboxylic acid transmembrane transporter activity) + +AnnotationAssertion(Annotation( "GOC:ai") "Enables the transfer of carboxylic acids from one side of a membrane to the other. Carboxylic acids are organic acids containing one or more carboxyl (COOH) groups or anions (COO-).") +AnnotationAssertion(Annotation(rdfs:label "Exchange of isocitrate and 2-oxoglutarate across the peroxisomal membrane") "Reactome:R-HSA-390347") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0046943") +AnnotationAssertion(rdfs:label "carboxylic acid transmembrane transporter activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (vesicle transport along microtubule) + +AnnotationAssertion(Annotation( "GOC:ecd") Annotation( "GOC:rl") "The directed movement of a vesicle along a microtubule, mediated by motor proteins. This process begins with the attachment of a vesicle to a microtubule, and ends when the vesicle reaches its final destination.") +AnnotationAssertion(Annotation( "GOC:rl") "microtubule-based vesicle localization") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0047496") +AnnotationAssertion(rdfs:label "vesicle transport along microtubule") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (antigen processing and presentation of peptide antigen) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") Annotation( "PMID:15771591") "The process in which an antigen-presenting cell expresses peptide antigen in association with an MHC protein complex on its cell surface, including proteolysis and transport steps for the peptide antigen both prior to and following assembly with the MHC protein complex. The peptide antigen is typically, but not always, processed from an endogenous or exogenous protein.") +AnnotationAssertion( "antigen presentation, peptide antigen") +AnnotationAssertion( "peptide antigen processing and presentation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048002") +AnnotationAssertion(rdfs:label "antigen processing and presentation of peptide antigen") +SubClassOf( ) + +# Class: (CCR chemokine receptor binding) + +AnnotationAssertion(Annotation( "GOC:ai") "Binding to a CCR chemokine receptor.") +AnnotationAssertion( "beta chemokine receptor binding") +AnnotationAssertion( "CCR chemokine receptor ligand") +AnnotationAssertion( "beta chemokine receptor ligand") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0048020") +AnnotationAssertion(rdfs:label "CCR chemokine receptor binding") +SubClassOf( ) + +# Class: (monosaccharide binding) + +AnnotationAssertion(Annotation( "GOC:jid") "Binding to a monosaccharide. Monosaccharides are the simplest carbohydrates; they are polyhydroxy aldehydes H[CH(OH)]nC(=O)H or polyhydroxy ketones H[CHOH]nC(=O)[CHOH]mH with three or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides.") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0048029") +AnnotationAssertion(rdfs:label "monosaccharide binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (embryonic eye morphogenesis) + +AnnotationAssertion(Annotation( "GOC:jid") "The process occurring in the embryo by which the anatomical structures of the post-embryonic eye are generated and organized.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048048") +AnnotationAssertion(rdfs:label "embryonic eye morphogenesis") +SubClassOf( ) +SubClassOf( ) + +# Class: (compound eye corneal lens development) + +AnnotationAssertion(Annotation( "GOC:jid") "The process whose specific outcome is the progression of the corneal lens in the compound eye over time, from its formation to the mature structure. The corneal lens is a chitinous extracellular secretion of the four underlying cone cells and the pigment cells.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048058") +AnnotationAssertion(rdfs:label "compound eye corneal lens development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectAllValuesFrom( )) + +# Class: (developmental pigmentation) + +AnnotationAssertion(Annotation( "ISBN:0582227089") "The developmental process that results in the deposition of coloring matter in an organism, tissue or cell.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "pigmentation during development") +AnnotationAssertion( "GO:0048066") +AnnotationAssertion(rdfs:label "developmental pigmentation") +SubClassOf( ) + +# Class: (regulation of developmental pigmentation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GOC:tb") "Any process that modulates the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism.") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "regulation of pigmentation during development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048070") +AnnotationAssertion(rdfs:label "regulation of developmental pigmentation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of developmental pigmentation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GOC:tb") "Any process that decreases the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism.") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "down regulation of developmental pigmentation") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "down-regulation of developmental pigmentation") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "downregulation of developmental pigmentation") +AnnotationAssertion( "inhibition of pigmentation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048086") +AnnotationAssertion(rdfs:label "negative regulation of developmental pigmentation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of developmental pigmentation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GOC:tb") "Any process that increases the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism.") +AnnotationAssertion(Annotation( "GOC:dph") "up regulation of developmental pigmentation") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "up-regulation of developmental pigmentation") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "upregulation of developmental pigmentation") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "activation of developmental pigmentation") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "stimulation of developmental pigmentation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048087") +AnnotationAssertion(rdfs:label "positive regulation of developmental pigmentation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (somatic stem cell division) + +AnnotationAssertion(Annotation( "GOC:jid") Annotation( "ISBN:0582227089") "The self-renewing division of a somatic stem cell, a stem cell that can give rise to cell types of the body other than those of the germ-line.") +AnnotationAssertion( "somatic stem cell renewal") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048103") +AnnotationAssertion(rdfs:label "somatic stem cell division") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (female germ-line stem cell asymmetric division) + +AnnotationAssertion(Annotation( "GOC:jid") Annotation( "GOC:mtg_sensu") "The self-renewing division of a germline stem cell in the female gonad, to produce a daughter stem cell and a daughter germ cell, which will divide to form the female gametes.") +AnnotationAssertion( "GO:0048141") +AnnotationAssertion( "female germ-line stem cell renewal") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048132") +AnnotationAssertion(rdfs:label "female germ-line stem cell asymmetric division") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectAllValuesFrom( )) + +# Class: (spermatocyte division) + +AnnotationAssertion(Annotation( "GOC:jid") Annotation( "GOC:pr") Annotation( "ISBN:0879694238") "The meiotic divisions undergone by the primary and secondary spermatocytes to produce haploid spermatids.") +AnnotationAssertion( "spermatocyte cell division") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048137") +AnnotationAssertion(rdfs:label "spermatocyte division") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (astrocyte activation) + +AnnotationAssertion(Annotation( "GOC:mgi_curators") Annotation( "PMID:10526094") Annotation( "PMID:10695728") Annotation( "PMID:12529254") Annotation( "PMID:12580336") Annotation( "PMID:9585813") "A change in morphology and behavior of an astrocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048143") +AnnotationAssertion(rdfs:label "astrocyte activation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (fibroblast proliferation) + +AnnotationAssertion(Annotation( "GOC:jid") "The multiplication or reproduction of fibroblast cells, resulting in the expansion of the fibroblast population.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048144") +AnnotationAssertion(rdfs:label "fibroblast proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of fibroblast proliferation) + +AnnotationAssertion(Annotation( "GOC:jid") "Any process that modulates the frequency, rate or extent of multiplication or reproduction of fibroblast cells.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048145") +AnnotationAssertion(rdfs:label "regulation of fibroblast proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of fibroblast proliferation) + +AnnotationAssertion(Annotation( "GOC:jid") "Any process that activates or increases the frequency, rate or extent of multiplication or reproduction of fibroblast cells.") +AnnotationAssertion( "up regulation of fibroblast proliferation") +AnnotationAssertion( "up-regulation of fibroblast proliferation") +AnnotationAssertion( "upregulation of fibroblast proliferation") +AnnotationAssertion( "activation of fibroblast proliferation") +AnnotationAssertion( "stimulation of fibroblast proliferation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048146") +AnnotationAssertion(rdfs:label "positive regulation of fibroblast proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of fibroblast proliferation) + +AnnotationAssertion(Annotation( "GOC:jid") "Any process that stops, prevents, or reduces the frequency, rate or extent of multiplication or reproduction of fibroblast cells.") +AnnotationAssertion( "down regulation of fibroblast proliferation") +AnnotationAssertion( "down-regulation of fibroblast proliferation") +AnnotationAssertion( "downregulation of fibroblast proliferation") +AnnotationAssertion( "inhibition of fibroblast proliferation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048147") +AnnotationAssertion(rdfs:label "negative regulation of fibroblast proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (multi-layer follicle stage) + +AnnotationAssertion(Annotation( "GOC:jid") Annotation( "GOC:mtg_sensu") Annotation( "ISBN:0198542771") "The stage in oogenesis when many layers of follicle cells surround the oocyte. There is a yolk nucleus (Balbiani's Body) near the germinal vesicle.") +AnnotationAssertion( "mammalian oogenesis stage 5") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048162") +AnnotationAssertion(rdfs:label "multi-layer follicle stage") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectAllValuesFrom( )) + +# Class: (fused antrum stage) + +AnnotationAssertion(Annotation( "GOC:jid") Annotation( "GOC:mtg_sensu") Annotation( "ISBN:0198542771") "The stage in oogenesis when the antral spaces fuse to form a single antral space. The oocyte is suspended in the cumulus oophorous and the first polar body in the perivitelline space.") +AnnotationAssertion( "mammalian oogenesis stage 8") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048165") +AnnotationAssertion(rdfs:label "fused antrum stage") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectAllValuesFrom( )) + +# Class: (Golgi vesicle transport) + +AnnotationAssertion(Annotation( "GOC:jid") Annotation( "ISBN:0716731363") Annotation( "PMID:10219233") "The directed movement of substances into, out of or within the Golgi apparatus, mediated by vesicles.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "Golgi-derived vesicle transport") +AnnotationAssertion( "GO:0048193") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "Golgi vesicle transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (Golgi vesicle budding) + +AnnotationAssertion(Annotation( "GOC:jid") Annotation( "ISBN:0716731363") Annotation( "PMID:10219233") "The evagination of the Golgi membrane, resulting in formation of a vesicle.") +AnnotationAssertion( "Golgi-derived vesicle budding") +AnnotationAssertion( "dictyosome vesicle budding") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048194") +AnnotationAssertion(rdfs:label "Golgi vesicle budding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (vesicle targeting, to, from or within Golgi) + +AnnotationAssertion(Annotation( "GOC:jid") Annotation( "GOC:mah") Annotation( "ISBN:0716731363") Annotation( "PMID:10219233") "The process in which vesicles are directed to specific destination membranes during transport to, from or within the Golgi apparatus; mediated by the addition of specific coat proteins, including COPI and COPII proteins and clathrin, to the membrane during vesicle formation.") +AnnotationAssertion( "Golgi vesicle targeting") +AnnotationAssertion( "dictyosome vesicle targeting") +AnnotationAssertion( "vesicle targeting, to, from or within dictyosome") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048199") +AnnotationAssertion(rdfs:label "vesicle targeting, to, from or within Golgi") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (regulation of vesicle targeting, to, from or within Golgi) + +AnnotationAssertion(Annotation( "GOC:jid") Annotation( "GOC:mah") Annotation( "ISBN:0716731363") Annotation( "PMID:10219233") "Any process that modulates the frequency, rate, or destination of vesicle-mediated transport to, from or within the Golgi apparatus.") +AnnotationAssertion( "regulation of Golgi vesicle targeting") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048209") +AnnotationAssertion(rdfs:label "regulation of vesicle targeting, to, from or within Golgi") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) # Class: (male gamete generation) @@ -37732,6 +88661,24 @@ SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (epinephrine transport) + +AnnotationAssertion(Annotation( "GOC:jid") "The directed movement of epinephrine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion( "adrenaline transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048241") +AnnotationAssertion(rdfs:label "epinephrine transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (epinephrine secretion) + +AnnotationAssertion(Annotation( "GOC:ef") Annotation( "GOC:jid") "The regulated release of epinephrine by a cell. Epinephrine is a catecholamine hormone secreted by the adrenal medulla and a neurotransmitter, released by certain neurons and active in the central nervous system.") +AnnotationAssertion( "adrenaline secretion") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048242") +AnnotationAssertion(rdfs:label "epinephrine secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (norepinephrine secretion) AnnotationAssertion(Annotation( "GOC:ef") Annotation( "GOC:jid") "The regulated release of norepinephrine by a cell. Norepinephrine is a catecholamine and it acts as a hormone and as a neurotransmitter of most of the sympathetic nervous system.") @@ -37739,17 +88686,278 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0048243") AnnotationAssertion(rdfs:label "norepinephrine secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (macrophage chemotaxis) + +AnnotationAssertion(Annotation( "GOC:jid") "The movement of a macrophage in response to an external stimulus.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048246") +AnnotationAssertion(rdfs:label "macrophage chemotaxis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (lymphocyte chemotaxis) + +AnnotationAssertion(Annotation( "GOC:hjd") Annotation( "GOC:jid") Annotation( "PMID:12391252") "The directed movement of a lymphocyte in response to an external stimulus.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048247") +AnnotationAssertion(rdfs:label "lymphocyte chemotaxis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (elastic fiber assembly) + +AnnotationAssertion(Annotation( "GOC:jid") Annotation( "PMID:10841810") Annotation( "PMID:12615674") "Assembly of the extracellular matrix fibers that enables the matrix to recoil after transient stretching.") +AnnotationAssertion( "elastic fibre assembly") +AnnotationAssertion(Annotation( "GOC:BHF") "elastin fiber assembly") +AnnotationAssertion(Annotation( "GOC:BHF") "elastin fibre assembly") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048251") +AnnotationAssertion(rdfs:label "elastic fiber assembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (vesicle fusion with Golgi apparatus) + +AnnotationAssertion(Annotation( "GOC:jid") "The joining of the lipid bilayer membrane around a vesicle to the lipid bilayer membrane around the Golgi.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048280") +AnnotationAssertion(rdfs:label "vesicle fusion with Golgi apparatus") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (organelle fusion) + +AnnotationAssertion(Annotation( "GOC:jid") "The creation of a single organelle from two or more organelles.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048284") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "organelle fusion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (organelle fission) + +AnnotationAssertion(Annotation( "GOC:jid") "The creation of two or more organelles by division of one organelle.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048285") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "organelle fission") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (lung alveolus development) + +AnnotationAssertion(Annotation( "GOC:mtg_lung") Annotation( "PMID:9751757") "The process whose specific outcome is the progression of the alveolus over time, from its formation to the mature structure. The alveolus is a sac for holding air in the lungs; formed by the terminal dilation of air passageways.") +AnnotationAssertion(Annotation( "PMID:17911382") "alveolarization") +AnnotationAssertion(Annotation( "GOC:17911382") "alveologenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048286") +AnnotationAssertion(rdfs:label "lung alveolus development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (nuclear membrane fusion involved in karyogamy) + +AnnotationAssertion(Annotation( "GOC:jid") "The joining of 2 or more lipid bilayer membranes that surround the nucleus during the creation of a single nucleus from multiple nuclei.") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "nuclear membrane fusion during karyogamy") +AnnotationAssertion( "GO:0048288") +AnnotationAssertion(rdfs:label "nuclear membrane fusion involved in karyogamy") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (calcium-dependent protein binding) + +AnnotationAssertion(Annotation( "GOC:jid") Annotation( "PMID:10485905") "Binding to a protein or protein complex in the presence of calcium.") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0048306") +AnnotationAssertion(rdfs:label "calcium-dependent protein binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (organelle inheritance) + +AnnotationAssertion(Annotation( "GOC:jid") "The partitioning of organelles between daughter cells at cell division.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048308") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "organelle inheritance") +SubClassOf( ) + +# Class: (Golgi inheritance) + +AnnotationAssertion(Annotation( "GOC:jid") Annotation( "PMID:12851069") "The partitioning of Golgi apparatus between daughter cells at cell division.") +AnnotationAssertion( "Golgi apparatus inheritance") +AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "Golgi division") +AnnotationAssertion( "Golgi partitioning") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048313") +AnnotationAssertion(rdfs:label "Golgi inheritance") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (axial mesoderm development) + +AnnotationAssertion(Annotation( "GOC:dgh") "The process whose specific outcome is the progression of the axial mesoderm over time, from its formation to the mature structure. The axial mesoderm includes the prechordal mesoderm and the chordamesoderm. It gives rise to the prechordal plate and to the notochord.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048318") +AnnotationAssertion(rdfs:label "axial mesoderm development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (axial mesoderm morphogenesis) + +AnnotationAssertion(Annotation( "GOC:go_curators") "The process in which the anatomical structures of the axial mesoderm are generated and organized.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048319") +AnnotationAssertion(rdfs:label "axial mesoderm morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (axial mesoderm formation) + +AnnotationAssertion(Annotation( "GOC:dgh") "The process that gives rise to the axial mesoderm. This process pertains to the initial formation of the structure from unspecified parts.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048320") +AnnotationAssertion(rdfs:label "axial mesoderm formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (mesoderm morphogenesis) AnnotationAssertion(Annotation( "GOC:go_curators") "The process in which the anatomical structures of the mesoderm are generated and organized.") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0048332") AnnotationAssertion(rdfs:label "mesoderm morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (mesodermal cell differentiation) + +AnnotationAssertion(Annotation( "GOC:dgh") "The process in which a relatively unspecialized cell acquires the specialized features of a mesoderm cell.") +AnnotationAssertion( "mesoderm cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048333") +AnnotationAssertion(rdfs:label "mesodermal cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (paraxial mesoderm development) + +AnnotationAssertion(Annotation( "GOC:dgh") "The process whose specific outcome is the progression of the paraxial mesoderm over time, from its formation to the mature structure. The paraxial mesoderm is the mesoderm located bilaterally adjacent to the notochord and neural tube.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048339") +AnnotationAssertion(rdfs:label "paraxial mesoderm development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (paraxial mesoderm morphogenesis) + +AnnotationAssertion(Annotation( "GOC:go_curators") "The process in which the anatomical structures of the paraxial mesoderm are generated and organized.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048340") +AnnotationAssertion(rdfs:label "paraxial mesoderm morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (paraxial mesoderm formation) + +AnnotationAssertion(Annotation( "GOC:dgh") "The process that gives rise to the paraxial mesoderm. This process pertains to the initial formation of the structure from unspecified parts.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048341") +AnnotationAssertion(rdfs:label "paraxial mesoderm formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (lateral mesoderm development) + +AnnotationAssertion(Annotation( "GOC:go_curators") "The process whose specific outcome is the progression of the lateral mesoderm over time, from its formation to the mature structure.") +AnnotationAssertion( "lateral plate mesoderm development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048368") +AnnotationAssertion(rdfs:label "lateral mesoderm development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (lateral mesoderm morphogenesis) + +AnnotationAssertion(Annotation( "GOC:go_curators") "The process in which the anatomical structures of the lateral mesoderm are generated and organized.") +AnnotationAssertion( "lateral plate mesoderm morphogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048369") +AnnotationAssertion(rdfs:label "lateral mesoderm morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (lateral mesoderm formation) + +AnnotationAssertion(Annotation( "GOC:jid") "The process that gives rise to the lateral mesoderm. This process pertains to the initial formation of the structure from unspecified parts.") +AnnotationAssertion( "lateral plate mesoderm biosynthesis") +AnnotationAssertion( "lateral plate mesoderm formation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048370") +AnnotationAssertion(rdfs:label "lateral mesoderm formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (mesectoderm development) + +AnnotationAssertion(Annotation( "GOC:jid") "The process whose specific outcome is the progression of the mesectoderm over time, from its formation to the mature structure. In animal embryos, mesectoderm development processes give rise to both mesoderm and ectoderm tissues.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048383") +AnnotationAssertion(rdfs:label "mesectoderm development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (intermediate mesoderm development) + +AnnotationAssertion(Annotation( "GOC:dgh") "The process whose specific outcome is the progression of the intermediate mesoderm over time, from its formation to the mature structure. The intermediate mesoderm is located between the lateral mesoderm and the paraxial mesoderm. It develops into the kidney and gonads.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048389") +AnnotationAssertion(rdfs:label "intermediate mesoderm development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (intermediate mesoderm morphogenesis) + +AnnotationAssertion(Annotation( "GOC:go_curators") "The process in which the anatomical structures of the intermediate mesoderm are generated and organized.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048390") +AnnotationAssertion(rdfs:label "intermediate mesoderm morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (intermediate mesoderm formation) + +AnnotationAssertion(Annotation( "GOC:dgh") "The process that gives rise to the intermediate mesoderm. This process pertains to the initial formation of the structure from unspecified parts.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048391") +AnnotationAssertion(rdfs:label "intermediate mesoderm formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (cell development) AnnotationAssertion(Annotation( "GOC:go_curators") "The cellular developmental process in which a specific cell progresses from an immature to a mature state. Cell development start once cell commitment has taken place.") @@ -37759,6 +88967,7 @@ AnnotationAssertion(Annotation( "GO:0048468") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "cell development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) @@ -37772,6 +88981,7 @@ AnnotationAssertion(Annotation( "GO:0048469") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "cell maturation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) @@ -37786,12 +88996,63 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:0048477") AnnotationAssertion(rdfs:label "oogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectAllValuesFrom( )) +# Class: (autonomic nervous system development) + +AnnotationAssertion(Annotation( "FMA:9905") Annotation( "GOC:jid") Annotation( "GOC:sr") "The process whose specific outcome is the progression of the autonomic nervous system over time, from its formation to the mature structure. The autonomic nervous system is composed of neurons that are not under conscious control, and is comprised of two antagonistic components, the sympathetic and parasympathetic nervous systems. The autonomic nervous system regulates key functions including the activity of the cardiac (heart) muscle, smooth muscles (e.g. of the gut), and glands.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048483") +AnnotationAssertion(rdfs:label "autonomic nervous system development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (enteric nervous system development) + +AnnotationAssertion(Annotation( "FMA:66070") Annotation( "GOC:jid") Annotation( "GOC:sr") "The process whose specific outcome is the progression of the enteric nervous system over time, from its formation to the mature structure. The enteric nervous system is composed of two ganglionated neural plexuses in the gut wall which form one of the three major divisions of the autonomic nervous system. The enteric nervous system innervates the gastrointestinal tract, the pancreas, and the gallbladder. It contains sensory neurons, interneurons, and motor neurons. Thus the circuitry can autonomously sense the tension and the chemical environment in the gut and regulate blood vessel tone, motility, secretions, and fluid transport. The system is itself governed by the central nervous system and receives both parasympathetic and sympathetic innervation.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048484") +AnnotationAssertion(rdfs:label "enteric nervous system development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (sympathetic nervous system development) + +AnnotationAssertion(Annotation( "FMA:9906") Annotation( "GOC:jid") Annotation( "GOC:sr") "The process whose specific outcome is the progression of the sympathetic nervous system over time, from its formation to the mature structure. The sympathetic nervous system is one of the two divisions of the vertebrate autonomic nervous system (the other being the parasympathetic nervous system). The sympathetic preganglionic neurons have their cell bodies in the thoracic and lumbar regions of the spinal cord and connect to the paravertebral chain of sympathetic ganglia. Innervate heart and blood vessels, sweat glands, viscera and the adrenal medulla. Most sympathetic neurons, but not all, use noradrenaline as a post-ganglionic neurotransmitter.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048485") +AnnotationAssertion(rdfs:label "sympathetic nervous system development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (parasympathetic nervous system development) + +AnnotationAssertion(Annotation( "FMA:9907") Annotation( "GOC:jid") Annotation( "GOC:sr") "The process whose specific outcome is the progression of the parasympathetic nervous system over time, from its formation to the mature structure. The parasympathetic nervous system is one of the two divisions of the vertebrate autonomic nervous system. Parasympathetic nerves emerge cranially as pre ganglionic fibers from oculomotor, facial, glossopharyngeal and vagus and from the sacral region of the spinal cord. Most neurons are cholinergic and responses are mediated by muscarinic receptors. The parasympathetic system innervates, for example: salivary glands, thoracic and abdominal viscera, bladder and genitalia.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048486") +AnnotationAssertion(rdfs:label "parasympathetic nervous system development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (regulation of timing of cell differentiation) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GOC:tb") "The process controlling the activation and/or rate at which relatively unspecialized cells acquire specialized features. Any process that modulates the rate, frequency or extent of the XXX at a consistent predetermined time point during its development.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "timing of cell differentiation") +AnnotationAssertion( "GO:0048505") +AnnotationAssertion(rdfs:label "regulation of timing of cell differentiation") +SubClassOf( ) +SubClassOf( ) + # Class: (rhythmic process) AnnotationAssertion(Annotation( "GOC:jid") "Any process pertinent to the generation and maintenance of rhythms in the physiology of an organism.") @@ -37804,6 +89065,17 @@ SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectAllValuesFrom( )) +# Class: (circadian behavior) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:go_curators") Annotation( "GOC:pr") "The specific behavior of an organism that recurs with a regularity of approximately 24 hours.") +AnnotationAssertion( "circadian rhythm behavior") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048512") +AnnotationAssertion(rdfs:label "circadian behavior") +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + # Class: (animal organ development) AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:jid") "Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.") @@ -37816,6 +89088,18 @@ AnnotationAssertion( "animal organ development") SubClassOf( ) +# Class: (blood vessel morphogenesis) + +AnnotationAssertion(Annotation( "GOC:jid") "The process in which the anatomical structures of blood vessels are generated and organized. The blood vessel is the vasculature carrying blood.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048514") +AnnotationAssertion(rdfs:label "blood vessel morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (spermatid differentiation) AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:jid") "The process whose specific outcome is the progression of a spermatid over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.") @@ -37823,6 +89107,7 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0048515") AnnotationAssertion(rdfs:label "spermatid differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ) @@ -37842,6 +89127,7 @@ AnnotationAssertion( "GO:0048518") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "positive regulation of biological process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) # Class: (negative regulation of biological process) @@ -37857,6 +89143,7 @@ AnnotationAssertion( "GO:0048519") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "negative regulation of biological process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) # Class: (positive regulation of behavior) @@ -38049,16 +89336,6 @@ SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (post-embryonic animal organ morphogenesis) - -AnnotationAssertion(Annotation( "GOC:jid") "Morphogenesis, during the post-embryonic phase, of an animal tissue or tissues that work together to perform a specific function or functions. Morphogenesis pertains to process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048563") -AnnotationAssertion(rdfs:label "post-embryonic animal organ morphogenesis") -SubClassOf( ) -SubClassOf( ) -SubClassOf( ObjectSomeValuesFrom( )) - # Class: (digestive tract development) AnnotationAssertion(Annotation( "GOC:go_curators") "The process whose specific outcome is the progression of the digestive tract over time, from its formation to the mature structure. The digestive tract is the anatomical structure through which food passes and is processed.") @@ -38085,16 +89362,6 @@ SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) -# Class: (post-embryonic animal organ development) - -AnnotationAssertion(Annotation( "GOC:jid") "Development, taking place during the post-embryonic phase of an animal tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.") -AnnotationAssertion( "post-embryonic animal organogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion( "GO:0048569") -AnnotationAssertion(rdfs:label "post-embryonic animal organ development") -SubClassOf( ) -SubClassOf( ) - # Class: (notochord morphogenesis) AnnotationAssertion(Annotation( "GOC:jid") "The process in which the anatomical structures of the notochord are generated and organized. The notochord is a mesoderm-derived structure located ventral of the developing nerve cord. In vertebrates, the notochord serves as a core around which other mesodermal cells form the vertebrae. In the most primitive chordates, which lack vertebrae, the notochord persists as a substitute for a vertebral column.") @@ -38153,8 +89420,42 @@ AnnotationAssertion( ) AnnotationAssertion(rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.") AnnotationAssertion(rdfs:label "regulation of response to stimulus") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (positive regulation of response to stimulus) + +AnnotationAssertion(Annotation( "GOC:jid") "Any process that activates, maintains or increases the rate of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.") +AnnotationAssertion( "up regulation of response to stimulus") +AnnotationAssertion( "up-regulation of response to stimulus") +AnnotationAssertion( "upregulation of response to stimulus") +AnnotationAssertion( "activation of response to stimulus") +AnnotationAssertion( "stimulation of response to stimulus") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048584") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.") +AnnotationAssertion(rdfs:label "positive regulation of response to stimulus") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of response to stimulus) + +AnnotationAssertion(Annotation( "GOC:jid") "Any process that stops, prevents, or reduces the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.") +AnnotationAssertion( "down regulation of response to stimulus") +AnnotationAssertion( "down-regulation of response to stimulus") +AnnotationAssertion( "downregulation of response to stimulus") +AnnotationAssertion( "inhibition of response to stimulus") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048585") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.") +AnnotationAssertion(rdfs:label "negative regulation of response to stimulus") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + # Class: (developmental cell growth) AnnotationAssertion(Annotation( "GOC:go_curators") Annotation( "GOC:isa_complete") "The growth of a cell, where growth contributes to the progression of the cell over time from one condition to another.") @@ -38172,6 +89473,42 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:0048589") AnnotationAssertion(rdfs:label "developmental growth") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (eye morphogenesis) + +AnnotationAssertion(Annotation( "GOC:jid") Annotation( "GOC:mtg_sensu") "The process in which the anatomical structures of the eye are generated and organized.") +AnnotationAssertion( "GO:0048748") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048592") +AnnotationAssertion(rdfs:label "eye morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (camera-type eye morphogenesis) + +AnnotationAssertion(Annotation( "GOC:jid") Annotation( "GOC:mtg_sensu") "The process in which the anatomical structures of the eye are generated and organized. The camera-type eye is an organ of sight that receives light through an aperture and focuses it through a lens, projecting it on a photoreceptor field.") +AnnotationAssertion( "GO:0048594") +AnnotationAssertion( "GO:0048595") +AnnotationAssertion(Annotation( "GOC:dph") "camera-style eye morphogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048593") +AnnotationAssertion(rdfs:label "camera-type eye morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (embryonic camera-type eye morphogenesis) + +AnnotationAssertion(Annotation( "GOC:jid") Annotation( "GOC:mtg_sensu") "The process in which the anatomical structures of the eye are generated and organized during embryonic development.") +AnnotationAssertion( "embryonic eye morphogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048596") +AnnotationAssertion(rdfs:label "embryonic camera-type eye morphogenesis") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) # Class: (embryonic morphogenesis) @@ -38185,6 +89522,30 @@ SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (oocyte development) + +AnnotationAssertion(Annotation( "GOC:go_curators") "The process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048599") +AnnotationAssertion(rdfs:label "oocyte development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (oocyte morphogenesis) + +AnnotationAssertion(Annotation( "GOC:go_curators") "The process in which the structures of an oocyte are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of an oocyte.") +AnnotationAssertion( "oocyte morphogenesis during differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048601") +AnnotationAssertion(rdfs:label "oocyte morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectAllValuesFrom( )) + # Class: (reproductive structure development) AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:isa_complete") Annotation( "GOC:jid") "The reproductive developmental process whose specific outcome is the progression of somatic structures that will be used in the process of creating new individuals from one or more parents, from their formation to the mature structures.") @@ -38207,6 +89568,211 @@ AnnotationAssertion(rdfs:label "mult SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (embryonic hindgut morphogenesis) + +AnnotationAssertion(Annotation( "GOC:jid") Annotation( "GOC:rc") "The process in which the anatomical structures of the hindgut are generated and organized, during the embryonic phase.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048619") +AnnotationAssertion(rdfs:label "embryonic hindgut morphogenesis") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (myoblast development) + +AnnotationAssertion(Annotation( "CL:0000056") Annotation( "GOC:dph") Annotation( "GOC:mtg_muscle") "The process whose specific outcome is the progression of the myoblast over time, from its formation to the mature structure. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048627") +AnnotationAssertion(rdfs:label "myoblast development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (myoblast maturation) + +AnnotationAssertion(Annotation( "CL:0000056") Annotation( "GOC:dph") Annotation( "GOC:mtg_muscle") "A developmental process, independent of morphogenetic (shape) change, that is required for a myoblast to attain its fully functional state. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048628") +AnnotationAssertion(rdfs:label "myoblast maturation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (skeletal muscle tissue growth) + +AnnotationAssertion(Annotation( "GOC:lm") Annotation( "PMID:15726494") Annotation( "PMID:15907921") "The increase in size or mass of a skeletal muscle. This may be due to a change in the fiber number or size.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048630") +AnnotationAssertion(rdfs:label "skeletal muscle tissue growth") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (regulation of skeletal muscle tissue growth) + +AnnotationAssertion(Annotation( "GOC:lm") Annotation( "PMID:15726494") Annotation( "PMID:15907921") "Any process that modulates the frequency, rate or extent of skeletal muscle growth.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048631") +AnnotationAssertion(rdfs:label "regulation of skeletal muscle tissue growth") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of skeletal muscle tissue growth) + +AnnotationAssertion(Annotation( "GOC:lm") Annotation( "PMID:15726494") Annotation( "PMID:15907921") "Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle growth.") +AnnotationAssertion( "down regulation of skeletal muscle growth") +AnnotationAssertion( "down-regulation of skeletal muscle growth") +AnnotationAssertion( "downregulation of skeletal muscle growth") +AnnotationAssertion( "inhibition of skeletal muscle growth") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048632") +AnnotationAssertion(rdfs:label "negative regulation of skeletal muscle tissue growth") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of skeletal muscle tissue growth) + +AnnotationAssertion(Annotation( "GOC:lm") Annotation( "PMID:15726494") Annotation( "PMID:15907921") "Any process that activates, maintains or increases the rate of skeletal muscle growth.") +AnnotationAssertion( "up regulation of skeletal muscle growth") +AnnotationAssertion( "up-regulation of skeletal muscle growth") +AnnotationAssertion( "upregulation of skeletal muscle growth") +AnnotationAssertion( "activation of skeletal muscle growth") +AnnotationAssertion( "stimulation of skeletal muscle growth") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048633") +AnnotationAssertion(rdfs:label "positive regulation of skeletal muscle tissue growth") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (regulation of muscle organ development) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of muscle development.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048634") +AnnotationAssertion(rdfs:label "regulation of muscle organ development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of muscle organ development) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of muscle development.") +AnnotationAssertion( "down regulation of muscle development") +AnnotationAssertion( "down-regulation of muscle development") +AnnotationAssertion( "downregulation of muscle development") +AnnotationAssertion( "inhibition of muscle development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048635") +AnnotationAssertion(rdfs:label "negative regulation of muscle organ development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (positive regulation of muscle organ development) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates, maintains or increases the rate of muscle development.") +AnnotationAssertion( "up regulation of muscle development") +AnnotationAssertion( "up-regulation of muscle development") +AnnotationAssertion( "upregulation of muscle development") +AnnotationAssertion( "activation of muscle development") +AnnotationAssertion( "stimulation of muscle development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048636") +AnnotationAssertion(rdfs:label "positive regulation of muscle organ development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (regulation of developmental growth) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of developmental growth.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048638") +AnnotationAssertion(rdfs:label "regulation of developmental growth") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of developmental growth) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates, maintains or increases the rate of developmental growth.") +AnnotationAssertion( "up regulation of developmental growth") +AnnotationAssertion( "up-regulation of developmental growth") +AnnotationAssertion( "upregulation of developmental growth") +AnnotationAssertion( "activation of developmental growth") +AnnotationAssertion( "stimulation of developmental growth") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048639") +AnnotationAssertion(rdfs:label "positive regulation of developmental growth") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of developmental growth) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of developmental growth.") +AnnotationAssertion( "down regulation of developmental growth") +AnnotationAssertion( "down-regulation of developmental growth") +AnnotationAssertion( "downregulation of developmental growth") +AnnotationAssertion( "inhibition of developmental growth") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048640") +AnnotationAssertion(rdfs:label "negative regulation of developmental growth") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of skeletal muscle tissue development) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of skeletal muscle tissue development.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048641") +AnnotationAssertion(rdfs:label "regulation of skeletal muscle tissue development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of skeletal muscle tissue development) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle tissue development.") +AnnotationAssertion( "down regulation of skeletal muscle development") +AnnotationAssertion( "down-regulation of skeletal muscle development") +AnnotationAssertion( "downregulation of skeletal muscle development") +AnnotationAssertion( "inhibition of skeletal muscle development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048642") +AnnotationAssertion(rdfs:label "negative regulation of skeletal muscle tissue development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of skeletal muscle tissue development) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that activates, maintains or increases the rate of skeletal muscle tissue development.") +AnnotationAssertion( "up regulation of skeletal muscle development") +AnnotationAssertion( "up-regulation of skeletal muscle development") +AnnotationAssertion( "upregulation of skeletal muscle development") +AnnotationAssertion( "activation of skeletal muscle development") +AnnotationAssertion( "stimulation of skeletal muscle development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048643") +AnnotationAssertion(rdfs:label "positive regulation of skeletal muscle tissue development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (muscle organ morphogenesis) + +AnnotationAssertion(Annotation( "GOC:jid") "The process in which the anatomical structures of muscle are generated and organized.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048644") +AnnotationAssertion(rdfs:label "muscle organ morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (animal organ formation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:jid") "The process pertaining to the initial formation of an animal organ from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure, such as inductive events, and ends when the structural rudiment of the organ is recognizable, such as a condensation of mesenchymal cells into the organ rudiment. Organs are a natural part or structure in an animal or a plant, capable of performing some special action (termed its function), which is essential to the life or well-being of the whole. The heart and lungs are organs of animals, and the petal and leaf are organs of plants. In animals the organs are generally made up of several tissues, one of which usually predominates, and determines the principal function of the organ.") +AnnotationAssertion( "animal organ primordium initiation") +AnnotationAssertion( "initiation of an animal organ primordium") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048645") +AnnotationAssertion(rdfs:label "animal organ formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (anatomical structure formation involved in morphogenesis) AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GOC:tb") "The developmental process pertaining to the initial formation of an anatomical structure from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.") @@ -38219,16 +89785,208 @@ AnnotationAssertion(rdfs:label "anat SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (smooth muscle cell proliferation) + +AnnotationAssertion(Annotation( "CL:0000192") Annotation( "GOC:ebc") Annotation( "PMID:1840698") "The multiplication or reproduction of smooth muscle cells, resulting in the expansion of a cell population.") +AnnotationAssertion( "SMC proliferation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048659") +AnnotationAssertion(rdfs:label "smooth muscle cell proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of smooth muscle cell proliferation) + +AnnotationAssertion(Annotation( "CL:0000192") Annotation( "GOC:ebc") "Any process that modulates the frequency, rate or extent of smooth muscle cell proliferation.") +AnnotationAssertion( "regulation of SMC proliferation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048660") +AnnotationAssertion(rdfs:label "regulation of smooth muscle cell proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of smooth muscle cell proliferation) + +AnnotationAssertion(Annotation( "CL:0000192") Annotation( "GOC:ebc") "Any process that activates or increases the rate or extent of smooth muscle cell proliferation.") +AnnotationAssertion( "positive regulation of SMC proliferation") +AnnotationAssertion( "up regulation of smooth muscle cell proliferation") +AnnotationAssertion( "up-regulation of smooth muscle cell proliferation") +AnnotationAssertion( "upregulation of smooth muscle cell proliferation") +AnnotationAssertion( "activation of smooth muscle cell proliferation") +AnnotationAssertion( "stimulation of smooth muscle cell proliferation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048661") +AnnotationAssertion(rdfs:label "positive regulation of smooth muscle cell proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of smooth muscle cell proliferation) + +AnnotationAssertion(Annotation( "CL:0000192") Annotation( "GOC:ebc") "Any process that stops, prevents or reduces the rate or extent of smooth muscle cell proliferation.") +AnnotationAssertion( "down regulation of smooth muscle cell proliferation") +AnnotationAssertion( "down-regulation of smooth muscle cell proliferation") +AnnotationAssertion( "downregulation of smooth muscle cell proliferation") +AnnotationAssertion( "negative regulation of SMC proliferation") +AnnotationAssertion( "inhibition of smooth muscle cell proliferation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048662") +AnnotationAssertion(rdfs:label "negative regulation of smooth muscle cell proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (neuron development) + +AnnotationAssertion(Annotation( "GOC:dph") "The process whose specific outcome is the progression of a neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048666") +AnnotationAssertion(rdfs:label "neuron development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cell morphogenesis involved in neuron differentiation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "The process in which the structures of a neuron are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a neuron.") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "neuron morphogenesis involved in differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048667") +AnnotationAssertion(rdfs:label "cell morphogenesis involved in neuron differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (generation of neurons) + +AnnotationAssertion(Annotation( "GOC:nln") "The process in which nerve cells are generated. This includes the production of neuroblasts and their differentiation into neurons.") +AnnotationAssertion( "neuron generation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048699") +AnnotationAssertion(rdfs:label "generation of neurons") +SubClassOf( ) + +# Class: (skeletal system morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:dsf") Annotation( "GOC:jid") Annotation( "GOC:tb") "The process in which the anatomical structures of the skeleton are generated and organized.") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "skeletal morphogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048705") +AnnotationAssertion(rdfs:label "skeletal system morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (instar larval or pupal morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_sensu") Annotation( "GOC:rc") "The process, occurring during instar larval or pupal development, by which anatomical structures are generated and organized.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048707") +AnnotationAssertion(rdfs:label "instar larval or pupal morphogenesis") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (astrocyte differentiation) + +AnnotationAssertion(Annotation( "GOC:vp") Annotation( "PMID:15139015") "The process in which a relatively unspecialized cell acquires the specialized features of an astrocyte. An astrocyte is the most abundant type of glial cell. Astrocytes provide support for neurons and regulate the environment in which they function.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048708") +AnnotationAssertion(rdfs:label "astrocyte differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (oligodendrocyte differentiation) + +AnnotationAssertion(Annotation( "GOC:vp") Annotation( "PMID:15139015") "The process in which a relatively unspecialized cell acquires the specialized features of an oligodendrocyte. An oligodendrocyte is a type of glial cell involved in myelinating the axons of neurons in the central nervous system.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048709") +AnnotationAssertion(rdfs:label "oligodendrocyte differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (regulation of astrocyte differentiation) + +AnnotationAssertion(Annotation( "GOC:vp") Annotation( "PMID:15139015") "Any process that modulates the frequency, rate or extent of astrocyte differentiation.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048710") +AnnotationAssertion(rdfs:label "regulation of astrocyte differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of astrocyte differentiation) + +AnnotationAssertion(Annotation( "GOC:vp") Annotation( "PMID:15139015") "Any process that activates or increases the frequency, rate or extent of astrocyte differentiation.") +AnnotationAssertion( "up regulation of astrocyte differentiation") +AnnotationAssertion( "up-regulation of astrocyte differentiation") +AnnotationAssertion( "upregulation of astrocyte differentiation") +AnnotationAssertion( "activation of astrocyte differentiation") +AnnotationAssertion( "stimulation of astrocyte differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048711") +AnnotationAssertion(rdfs:label "positive regulation of astrocyte differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of astrocyte differentiation) + +AnnotationAssertion(Annotation( "GOC:vp") Annotation( "PMID:15139015") "Any process that stops, prevents, or reduces the frequency, rate or extent of astrocyte differentiation.") +AnnotationAssertion( "down regulation of astrocyte differentiation") +AnnotationAssertion( "down-regulation of astrocyte differentiation") +AnnotationAssertion( "downregulation of astrocyte differentiation") +AnnotationAssertion( "inhibition of astrocyte differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048712") +AnnotationAssertion(rdfs:label "negative regulation of astrocyte differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of oligodendrocyte differentiation) + +AnnotationAssertion(Annotation( "GOC:vp") Annotation( "PMID:15139015") "Any process that modulates the frequency, rate or extent of oligodendrocyte differentiation.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048713") +AnnotationAssertion(rdfs:label "regulation of oligodendrocyte differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of oligodendrocyte differentiation) + +AnnotationAssertion(Annotation( "GOC:vp") Annotation( "PMID:15139015") "Any process that activates or increases the frequency, rate or extent of oligodendrocyte differentiation.") +AnnotationAssertion( "up regulation of oligodendrocyte differentiation") +AnnotationAssertion( "up-regulation of oligodendrocyte differentiation") +AnnotationAssertion( "upregulation of oligodendrocyte differentiation") +AnnotationAssertion( "activation of oligodendrocyte differentiation") +AnnotationAssertion( "stimulation of oligodendrocyte differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048714") +AnnotationAssertion(rdfs:label "positive regulation of oligodendrocyte differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of oligodendrocyte differentiation) + +AnnotationAssertion(Annotation( "GOC:vp") Annotation( "PMID:15139015") "Any process that stops, prevents, or reduces the frequency, rate or extent of oligodendrocyte differentiation.") +AnnotationAssertion( "down regulation of oligodendrocyte differentiation") +AnnotationAssertion( "down-regulation of oligodendrocyte differentiation") +AnnotationAssertion( "downregulation of oligodendrocyte differentiation") +AnnotationAssertion( "inhibition of oligodendrocyte differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048715") +AnnotationAssertion(rdfs:label "negative regulation of oligodendrocyte differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (tissue morphogenesis) AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:jid") "The process in which the anatomical structures of a tissue are generated and organized.") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0048729") AnnotationAssertion(rdfs:label "tissue morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (epidermis morphogenesis) + +AnnotationAssertion(Annotation( "GOC:jid") Annotation( "UBERON:0001003") "The process in which the anatomical structures of the epidermis are generated and organized. The epidermis is the outer epithelial layer of an animal, it may be a single layer that produces an extracellular material (e.g. the cuticle of arthropods) or a complex stratified squamous epithelium, as in the case of many vertebrate species.") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:kmv") Annotation( "GOC:rk") "hypodermis morphogenesis") +AnnotationAssertion( "GO:0048730") +AnnotationAssertion(rdfs:label "epidermis morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (system development) AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:jid") "The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.") @@ -38236,6 +89994,7 @@ AnnotationAssertion( "GO:0048731") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "system development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) @@ -38245,9 +90004,182 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:0048732") AnnotationAssertion(rdfs:label "gland development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) +# Class: (sebaceous gland development) + +AnnotationAssertion(Annotation( "GOC:jid") "The process whose specific outcome is the progression of the sebaceous gland over time, from its formation to the mature structure.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048733") +AnnotationAssertion(rdfs:label "sebaceous gland development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (haltere morphogenesis) + +AnnotationAssertion(Annotation( "GOC:jid") Annotation( "GOC:rc") "The process in which the anatomical structures of a haltere are generated and organized.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048735") +AnnotationAssertion(rdfs:label "haltere morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (appendage development) + +AnnotationAssertion(Annotation( "GOC:jid") Annotation( "GOC:rc") "The process whose specific outcome is the progression of an appendage over time, from its formation to the mature structure. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048736") +AnnotationAssertion(rdfs:label "appendage development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (imaginal disc-derived appendage development) + +AnnotationAssertion(Annotation( "GOC:jid") Annotation( "GOC:mtg_sensu") Annotation( "GOC:rc") "The process whose specific outcome is the progression of an appendage over time, from its formation in the imaginal disc to the mature structure. An appendage is an organ or part that is attached to the trunk of an organism.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048737") +AnnotationAssertion(rdfs:label "imaginal disc-derived appendage development") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectAllValuesFrom( )) + +# Class: (cardiac muscle tissue development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GOC:lm") "The process whose specific outcome is the progression of cardiac muscle over time, from its formation to the mature structure.") +AnnotationAssertion( "heart muscle development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048738") +AnnotationAssertion(rdfs:label "cardiac muscle tissue development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (skeletal muscle fiber development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:ef") Annotation( "GOC:jid") Annotation( "GOC:lm") Annotation( "GOC:mtg_muscle") "The process whose specific outcome is the progression of the skeletal muscle fiber over time, from its formation to the mature structure. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast.") +AnnotationAssertion( "skeletal muscle fibre development") +AnnotationAssertion( "skeletal myofiber development") +AnnotationAssertion( "skeletal myofibre development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048741") +AnnotationAssertion(rdfs:label "skeletal muscle fiber development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (regulation of skeletal muscle fiber development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GOC:mtg_muscle") Annotation( "GOC:sm") "Any process that modulates the frequency, rate or extent of skeletal muscle fiber development. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast.") +AnnotationAssertion( "regulation of skeletal muscle fibre development") +AnnotationAssertion( "regulation of skeletal myofiber development") +AnnotationAssertion( "regulation of skeletal myofibre development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048742") +AnnotationAssertion(rdfs:label "regulation of skeletal muscle fiber development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (positive regulation of skeletal muscle fiber development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GOC:lm") Annotation( "GOC:mtg_muscle") "Any process that activates, maintains or increases the rate of skeletal muscle fiber development. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast.") +AnnotationAssertion( "positive regulation of skeletal muscle fibre development") +AnnotationAssertion( "positive regulation of skeletal myofiber development") +AnnotationAssertion( "positive regulation of skeletal myofibre development") +AnnotationAssertion( "up regulation of skeletal muscle fiber development") +AnnotationAssertion( "up-regulation of skeletal muscle fiber development") +AnnotationAssertion( "upregulation of skeletal muscle fiber development") +AnnotationAssertion( "activation of skeletal muscle fiber development") +AnnotationAssertion( "stimulation of skeletal muscle fiber development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048743") +AnnotationAssertion(rdfs:label "positive regulation of skeletal muscle fiber development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of skeletal muscle fiber development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GOC:lm") Annotation( "GOC:mtg_muscle") "Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle fiber development. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast.") +AnnotationAssertion( "down regulation of skeletal muscle fiber development") +AnnotationAssertion( "down-regulation of skeletal muscle fiber development") +AnnotationAssertion( "downregulation of skeletal muscle fiber development") +AnnotationAssertion( "negative regulation of skeletal muscle fibre development") +AnnotationAssertion( "negative regulation of skeletal myofiber development") +AnnotationAssertion( "negative regulation of skeletal myofibre development") +AnnotationAssertion( "inhibition of skeletal muscle fiber development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048744") +AnnotationAssertion(rdfs:label "negative regulation of skeletal muscle fiber development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (smooth muscle tissue development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GOC:lm") "The process whose specific outcome is the progression of smooth muscle over time, from its formation to the mature structure.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048745") +AnnotationAssertion(rdfs:label "smooth muscle tissue development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (compound eye development) + +AnnotationAssertion(Annotation( "GOC:jid") Annotation( "GOC:mtg_sensu") Annotation( "Wikipedia:Eye") "The process whose specific outcome is the progression of the compound eye over time, from its formation to the mature structure. The compound eye is an organ of sight that contains multiple repeating units, often arranged hexagonally. Each unit has its own lens and photoreceptor cell(s) and can generate either a single pixelated image or multiple images, per eye.") +AnnotationAssertion( "GO:0007456") +AnnotationAssertion(Annotation( "PMID:11735386") "insect-type retina development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048749") +AnnotationAssertion(rdfs:label "compound eye development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (compound eye corneal lens morphogenesis) + +AnnotationAssertion(Annotation( "GOC:jid") "The process in which the anatomical structures of the compound eye corneal lens are generated and organized.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048750") +AnnotationAssertion(rdfs:label "compound eye corneal lens morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectAllValuesFrom( )) + +# Class: (semicircular canal morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") "The process in which the anatomical structures of the semicircular canals are generated and organized.") +AnnotationAssertion( "embryonic semicircular canal morphogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048752") +AnnotationAssertion(rdfs:label "semicircular canal morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (pigment granule organization) + +AnnotationAssertion(Annotation( "GOC:rc") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a pigment granule.") +AnnotationAssertion( "pigment granule organisation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:mah") "pigment granule organization and biogenesis") +AnnotationAssertion( "GO:0048753") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "pigment granule organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (branching morphogenesis of an epithelial tube) AnnotationAssertion(Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") "The process in which the anatomical structures of branches in an epithelial tube are generated and organized. A tube is a long hollow cylinder.") @@ -38255,10 +90187,30 @@ AnnotationAssertion( "GOC:dph") Annotation( "GOC:tb") "tubulogenesis") AnnotationAssertion( "GO:0048754") AnnotationAssertion(rdfs:label "branching morphogenesis of an epithelial tube") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (branching morphogenesis of a nerve) + +AnnotationAssertion(Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") "The process in which the anatomical structures of branches in a nerve are generated and organized. This term refers to an anatomical structure (nerve) not a cell (neuron).") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048755") +AnnotationAssertion(rdfs:label "branching morphogenesis of a nerve") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (mesenchymal cell differentiation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:jid") "The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal cell. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048762") +AnnotationAssertion(rdfs:label "mesenchymal cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (pigment granule) AnnotationAssertion(Annotation( "GOC:jid") Annotation( "GOC:mh") "A small, subcellular membrane-bounded vesicle containing pigment and/or pigment precursor molecules. Pigment granule biogenesis is poorly understood, as pigment granules are derived from multiple sources including the endoplasmic reticulum, coated vesicles, lysosomes, and endosomes.") @@ -38270,6 +90222,7 @@ SubClassOf( (tissue remodeling) AnnotationAssertion(Annotation( "GOC:ebc") "The reorganization or renovation of existing tissues. This process can either change the characteristics of a tissue such as in blood vessel remodeling, or result in the dynamic equilibrium of a tissue such as in bone remodeling.") +AnnotationAssertion( "tissue remodelling") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0048771") AnnotationAssertion( ) @@ -38696,8 +90649,70 @@ AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "anatomical structure development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (neural nucleus development) + +AnnotationAssertion(Annotation( "GO_REF:0000021") "The biological process whose specific outcome is the progression of a neural nucleus from its initial condition to its mature state. A neural nucleus is an anatomical structure consisting of a discrete aggregate of neuronal soma.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048857") +AnnotationAssertion(rdfs:label "neural nucleus development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (cell projection morphogenesis) + +AnnotationAssertion(Annotation( "GO_REF:0000021") "The process in which the anatomical structures of a cell projection are generated and organized.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048858") +AnnotationAssertion(rdfs:label "cell projection morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (formation of anatomical boundary) + +AnnotationAssertion(Annotation( "GO_REF:0000021") "The process in which the limits of an anatomical structure are generated. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048859") +AnnotationAssertion(rdfs:label "formation of anatomical boundary") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (glioblast division) + +AnnotationAssertion(Annotation( "GOC:devbiol") "The process resulting in the physical partitioning and separation of a glioblast into daughter cells.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048860") +AnnotationAssertion(rdfs:label "glioblast division") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (stem cell differentiation) + +AnnotationAssertion(Annotation( "CL:0000034") Annotation( "GOC:isa_complete") "The process in which a relatively unspecialized cell acquires specialized features of a stem cell. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells.") +AnnotationAssertion( ) +AnnotationAssertion( "Wikipedia:Stem_cell_differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048863") +AnnotationAssertion(rdfs:label "stem cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses( ObjectSomeValuesFrom( )) + +# Class: (stem cell development) + +AnnotationAssertion(Annotation( "CL:0000034") Annotation( "GOC:isa_complete") "The process whose specific outcome is the progression of the stem cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to its specific fate.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048864") +AnnotationAssertion(rdfs:label "stem cell development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (cellular developmental process) AnnotationAssertion(Annotation( "GOC:isa_complete") "A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition.") @@ -38732,14 +90747,939 @@ AnnotationAssertion(rdfs:label "mult SubClassOf( ) SubClassOf( ) +# Class: (homeostasis of number of cells) + +AnnotationAssertion(Annotation( "GOC:isa_complete") "Any biological process involved in the maintenance of the steady-state number of cells within a population of cells.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/24218"^^xsd:anyURI) +AnnotationAssertion( "cell population homeostasis") +AnnotationAssertion(Annotation( "GOC:dph") "homeostasis of cell number") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048872") +AnnotationAssertion(rdfs:label "homeostasis of number of cells") +SubClassOf( ) + +# Class: (homeostasis of number of cells within a tissue) + +AnnotationAssertion(Annotation( "GOC:isa_complete") "Any biological process involved in the maintenance of the steady-state number of cells within a population of cells in a tissue.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048873") +AnnotationAssertion(rdfs:label "homeostasis of number of cells within a tissue") +SubClassOf( ) +SubClassOf( ) + +# Class: (chemical homeostasis) + +AnnotationAssertion(Annotation( "GOC:isa_complete") "Any biological process involved in the maintenance of an internal steady state of a chemical.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048878") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "chemical homeostasis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (sensory system development) + +AnnotationAssertion(Annotation( "GOC:dgh") "The process whose specific outcome is the progression of a sensory system over time from its formation to the mature structure.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048880") +AnnotationAssertion(rdfs:label "sensory system development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (mechanosensory lateral line system development) + +AnnotationAssertion(Annotation( "ISBN:0125296509") "The process whose specific outcome is the progression of the mechanosensory lateral line system over time, from its formation to the mature structure. The mechanosensory lateral line system consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head and body of all fishes and most amphibians. The neuromasts are innervated by several lateral line nerves, which project primarily to the hindbrain. The mechanosensory lateral line system is stimulated by local water displacements and vibrations, and detects propulsion of the fish through the water, as well as facilitating shoaling, prey capture, and predator and obstacle avoidance.") +AnnotationAssertion(Annotation( "ISBN:0125296509") "LL system development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048881") +AnnotationAssertion(rdfs:label "mechanosensory lateral line system development") +SubClassOf( ) + +# Class: (lateral line development) + +AnnotationAssertion(Annotation( "ISBN:0125296509") "The process whose specific outcome is the progression of the lateral line over time, from its formation to the mature structure. The lateral line consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head and body of all fishes and most amphibians. The lateral line develops from cranial ectodermal placodes situated behind the ear and between the eye and ear.") +AnnotationAssertion( "LL development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048882") +AnnotationAssertion(rdfs:label "lateral line development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (neuromast development) + +AnnotationAssertion(Annotation( "ISBN:0125296509") "The process whose specific outcome is the progression of the neuromast over time, from its formation to the mature structure. The neuromast is the sensory organ of the lateral line and is composed of a population of sensory hair cells, and nonsensory supporting cells and mantle cells. Neuromasts are located superficially on the epithelium or in lateral line canals.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048884") +AnnotationAssertion(rdfs:label "neuromast development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (neuromast hair cell differentiation) + +AnnotationAssertion(Annotation( "CL:0000856") Annotation( "ISBN:0125296509") "The process in which a relatively unspecialized cell acquires specialized features of a neuromast hair cell. Hair cells are the sensory receptors of the neuromast and are located in a portion of the neuromast called the sensory strip. Each hair cell of the neuromast is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. There are approximately seven hair cells within each neuromast, with each hair cell innervated by afferent and efferent neurons.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048886") +AnnotationAssertion(rdfs:label "neuromast hair cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (lateral line ganglion development) + +AnnotationAssertion(Annotation( "ISBN:0125296509") Annotation( "ISBN:0387968377") "The process whose specific outcome is the progression of the lateral line ganglion over time, from its formation to the mature structure. The lateral line ganglion develops from cranial ectodermal placodes situated between the eye and ear and behind the ear.") +AnnotationAssertion( "gLL ganglion development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048890") +AnnotationAssertion(rdfs:label "lateral line ganglion development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (lateral line ganglion neuron differentiation) + +AnnotationAssertion(Annotation( "PMID:15018940") "The process in which a relatively unspecialized cell acquires specialized features of a lateral line ganglion neuron.") +AnnotationAssertion( "gLL neuron differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048891") +AnnotationAssertion(rdfs:label "lateral line ganglion neuron differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (lateral line nerve development) + +AnnotationAssertion(Annotation( "ISBN:0125296509") "The process whose specific outcome is the progression of the lateral line nerve over time, form its formation to the mature structure. Lateral line nerves project primarily to an octavolateralis column in the hindbrain that consists of the medial octavolateralis nucleus (MON), the caudal octavolateralis nucleus, and the magnocellular nucleus.") +AnnotationAssertion( "nLL development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048892") +AnnotationAssertion(rdfs:label "lateral line nerve development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (lateral line nerve glial cell differentiation) + +AnnotationAssertion(Annotation( "PMID:12062041") "The process in which a relatively unspecialized cell acquires specialized features of a glial cell in a lateral line nerve.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048895") +AnnotationAssertion(rdfs:label "lateral line nerve glial cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (lateral line nerve glial cell migration) + +AnnotationAssertion(Annotation( "PMID:12062041") "The movement of a glial cell along the axons in a lateral line nerve.") +AnnotationAssertion( "glial cell migration in lateral line nerve") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048896") +AnnotationAssertion(rdfs:label "lateral line nerve glial cell migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (anterior lateral line system development) + +AnnotationAssertion(Annotation( "ISBN:0125296509") Annotation( "PMID:15018940") "The process whose specific outcome is the progression of the anterior lateral line system over time, from its formation to the mature structure. The anterior lateral line system develops from cranial ectodermal placodes, situated between the eye and the ear, that give rise to both the neuromasts and the anterior lateral line sensory nerves that innervate the neuromasts. The anterior lateral line system consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head of all fishes and most amphibians and are innervated by several lateral line nerves, which project to the hindbrain. The anterior lateral line system is stimulated by local water displacements and vibrations, and detects propulsion of the fish through the water, as well as facilitating shoaling, prey capture, and predator and obstacle avoidance.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "ALL system development") +AnnotationAssertion( "GO:0048898") +AnnotationAssertion(rdfs:label "anterior lateral line system development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (anterior lateral line development) + +AnnotationAssertion(Annotation( "ISBN:0125296509") "The process whose specific outcome is the progression of the anterior lateral line over time, from its formation to the mature structure. The anterior lateral line consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head of all fishes and most amphibians. The anterior lateral line develops from cranial ectodermal placodes situated between the eye and ear.") +AnnotationAssertion( "anterior LL development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048899") +AnnotationAssertion(rdfs:label "anterior lateral line development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (anterior lateral line neuromast development) + +AnnotationAssertion(Annotation( "ISBN:0125296509") "The process whose specific outcome is the progression of the anterior lateral line neuromast over time, from its formation to the mature structure. The neuromast is the sensory receptor of the anterior lateral line system and is composed of a population of sensory hair cells, and nonsensory supporting cells and mantle cells. Neuromast are located superficially on the epithelium or in lateral line canals.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048901") +AnnotationAssertion(rdfs:label "anterior lateral line neuromast development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (anterior lateral line neuromast hair cell differentiation) + +AnnotationAssertion(Annotation( "ISBN:0125296509") Annotation( "ISBN:0387968377") "The process in which a relatively unspecialized cell acquires specialized features of an anterior lateral line neuromast hair cell. Neuromast hair cells are the sensory receptors of the neuromast and are located in a portion of the neuromast called the sensory strip. Each hair cell of the neuromast is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. There are approximately seven hair cells within each neuromast, with each hair cell innervated by afferent and efferent neurons.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048903") +AnnotationAssertion(rdfs:label "anterior lateral line neuromast hair cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (anterior lateral line ganglion development) + +AnnotationAssertion(Annotation( "ISBN:0125296509") "The process whose specific outcome is the progression of the anterior lateral line ganglion over time, from its formation to the mature structure. The anterior lateral line ganglion develops from cranial ectodermal placodes situated between the eye and ear.") +AnnotationAssertion( "gALL development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048907") +AnnotationAssertion(rdfs:label "anterior lateral line ganglion development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (anterior lateral line nerve development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0125296509") "The process whose specific outcome is the progression of the anterior lateral line nerve over time, form its formation to the mature structure. The anterior lateral line nerve contains efferent axons that innervate hair cells of the ALL and afferent axons that project to an octavolateralis column in the hindbrain. The octavolateralis column consists of the medial octavolateralis nucleus (MON), the caudal octavolateralis nucleus, and the magnocellular nucleus.") +AnnotationAssertion( "GO:0021734") +AnnotationAssertion( "ALLN development") +AnnotationAssertion( "nALL development") +AnnotationAssertion( "rostral lateral line nerve development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048909") +AnnotationAssertion(rdfs:label "anterior lateral line nerve development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (anterior lateral line nerve glial cell differentiation) + +AnnotationAssertion(Annotation( "PMID:15832385") "The process in which a relatively unspecialized cell acquires specialized features of a glial cell in the anterior lateral line nerve.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048913") +AnnotationAssertion(rdfs:label "anterior lateral line nerve glial cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (posterior lateral line system development) + +AnnotationAssertion(Annotation( "ISBN:0125296509") Annotation( "PMID:15018940") "The process whose specific outcome is the progression of the posterior lateral line system over time, from its formation to the mature structure. The posterior lateral line system develops from cranial ectodermal placodes, situated behind the ear, that give rise to both the neuromasts and the posterior lateral line sensory nerves that innervate the neuromasts. The posterior lateral line system consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head of all fishes and most amphibians. The neuromasts are innervated by several lateral line nerves, which project primarily to the hindbrain. The posterior mechanosensory lateral line system is stimulated by local water displacements and vibrations, and detects propulsion of the fish through the water, as well as facilitating shoaling, prey capture, and predator and obstacle avoidance.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "PLL") +AnnotationAssertion( "GO:0048915") +AnnotationAssertion(rdfs:label "posterior lateral line system development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (posterior lateral line development) + +AnnotationAssertion(Annotation( "ISBN:0125296509") "The process whose specific outcome is the progression of the posterior lateral line over time, from its formation to the mature structure. The posterior lateral line consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the body and trunk of all fishes and most amphibians. The posterior lateral line develops from cranial ectodermal placodes situated behind the ear.") +AnnotationAssertion( "PLL development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048916") +AnnotationAssertion(rdfs:label "posterior lateral line development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (posterior lateral line ganglion development) + +AnnotationAssertion(Annotation( "ISBN:0125296509") Annotation( "ISBN:0387968377") "The process whose specific outcome is the progression of the posterior lateral line ganglion over time, from its formation to the mature structure. The posterior lateral line ganglion develops from cranial ectodermal placodes situated behind the ear.") +AnnotationAssertion( "gPLL development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048917") +AnnotationAssertion(rdfs:label "posterior lateral line ganglion development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (posterior lateral line nerve development) + +AnnotationAssertion(Annotation( "GOC:cls") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:jid") Annotation( "GO_REF:0000021") Annotation( "ISBN:0125296509") "The process whose specific outcome is the progression of the posterior lateral line nerve over time, from its formation to the mature structure. The posterior lateral line nerve innervates hair cells of the PLL and projects to an octavolateralis column in the hindbrain that consists of the medial octavolateralis nucleus (MON), the caudal octavolateralis nucleus, and the magnocellular nucleus.") +AnnotationAssertion( "GO:0021733") +AnnotationAssertion( "PLLN development") +AnnotationAssertion( "caudal lateral line nerve development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048918") +AnnotationAssertion(rdfs:label "posterior lateral line nerve development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (posterior lateral line neuromast development) + +AnnotationAssertion(Annotation( "ISBN:0125296509") "The process whose specific outcome is the progression of the posterior lateral line neuromast over time, from its formation to the mature structure. The neuromast is the sensory receptor of the anterior lateral line system and is composed of a population of sensory hair cells, and nonsensory supporting cells and mantle cells. Neuromast are located superficially on the epithelium or in lateral line canals.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048919") +AnnotationAssertion(rdfs:label "posterior lateral line neuromast development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (posterior lateral line neuromast hair cell differentiation) + +AnnotationAssertion(Annotation( "ISBN:0125296509") "The process in which a relatively unspecialized cell acquires specialized features of a posterior lateral line neuromast hair cell. (N.B. This may be development of neuromast hair cell type or a set of cell of neuromast hair cell type. This will involve the change of a cell or set of cells from one cell identity to another). Hair cells are the sensory receptors of the neuromast and are located in a portion of the neuromast called the sensory strip. Each hair cell of the neuromast is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. There are approximately seven hair cells within each neuromast, with each hair cell innervated by afferent and efferent neurons.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048923") +AnnotationAssertion(rdfs:label "posterior lateral line neuromast hair cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (lateral line system development) + +AnnotationAssertion(Annotation( "GOC:dgh") Annotation( "ISBN:0125296509") "The process whose specific outcome is the progression of the lateral line system over time, from its formation to the mature structure. The lateral line system is a network of sensory organs (neuromasts) and lateral line nerves located superficially on the skin or just under the skin in fluid-filled canals on the head and body of all fishes and most amphibians. The lateral line system develops from cranial ectodermal placodes situated between the eye and ear.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048925") +AnnotationAssertion(rdfs:label "lateral line system development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (posterior lateral line ganglion neuron differentiation) + +AnnotationAssertion(Annotation( "PMID:15018940") "The process in which a relatively unspecialized cell acquires specialized features of a neuron of the posterior lateral line ganglion.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048928") +AnnotationAssertion(rdfs:label "posterior lateral line ganglion neuron differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (posterior lateral line nerve glial cell differentiation) + +AnnotationAssertion(Annotation( "PMID:15832385") "The process in which a relatively unspecialized cell acquires specialized features of a glial cell in the posterior lateral line nerve.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048931") +AnnotationAssertion(rdfs:label "posterior lateral line nerve glial cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (peripheral nervous system neuron differentiation) + +AnnotationAssertion(Annotation( "GOC:dgh") "The process in which a relatively unspecialized cell acquires specialized features of a neuron whose cell body resides in the peripheral nervous system.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048934") +AnnotationAssertion(rdfs:label "peripheral nervous system neuron differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (peripheral nervous system neuron development) + +AnnotationAssertion(Annotation( "GOC:dgh") "The process whose specific outcome is the progression of a neuron whose cell body is located in the peripheral nervous system, from initial commitment of the cell to a neuronal fate, to the fully functional differentiated neuron.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048935") +AnnotationAssertion(rdfs:label "peripheral nervous system neuron development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (lateral line nerve glial cell development) + +AnnotationAssertion(Annotation( "GOC:dgh") "The process aimed at the progression of a lateral line glial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048937") +AnnotationAssertion(rdfs:label "lateral line nerve glial cell development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (lateral line nerve glial cell morphogenesis involved in differentiation) + +AnnotationAssertion(Annotation( "GOC:dgh") "The process in which the structure of a glial cell in a lateral line nerve is generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a glial cell in a lateral line nerve.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048938") +AnnotationAssertion(rdfs:label "lateral line nerve glial cell morphogenesis involved in differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (anterior lateral line nerve glial cell development) + +AnnotationAssertion(Annotation( "GOC:dgh") "The process aimed at the progression of a glial cell in the anterior lateral line nerve over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048939") +AnnotationAssertion(rdfs:label "anterior lateral line nerve glial cell development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (anterior lateral line nerve glial cell morphogenesis involved in differentiation) + +AnnotationAssertion(Annotation( "GOC:dgh") "The process in which the structures of a glial cell in the anterior lateral line nerve are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a glial cell in the anterior lateral line nerve.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048940") +AnnotationAssertion(rdfs:label "anterior lateral line nerve glial cell morphogenesis involved in differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (posterior lateral line nerve glial cell development) + +AnnotationAssertion(Annotation( "GOC:dgh") "The process aimed at the progression of a glial cell in the posterior lateral line nerve over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048941") +AnnotationAssertion(rdfs:label "posterior lateral line nerve glial cell development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (posterior lateral line nerve glial cell morphogenesis involved in differentiation) + +AnnotationAssertion(Annotation( "GOC:dgh") "The process in which the structures of a glial cell in the posterior lateral line nerve are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a glial cell in the posterior lateral line nerve.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0048942") +AnnotationAssertion(rdfs:label "posterior lateral line nerve glial cell morphogenesis involved in differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (chromosome localization) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process in which a chromosome is transported to, or maintained in, a specific location.") +AnnotationAssertion(Annotation( "GOC:mah") "chromosome localisation") +AnnotationAssertion( "establishment and maintenance of chromosome localization") +AnnotationAssertion( "establishment and maintenance of chromosome position") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0050000") +AnnotationAssertion(rdfs:label "chromosome localization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (catecholamine secretion) + +AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:ef") "The regulated release of catecholamines by a cell. The catecholamines are a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0050432") +AnnotationAssertion(rdfs:label "catecholamine secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of catecholamine secretion) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of the regulated release of catecholamines.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0050433") +AnnotationAssertion(rdfs:label "regulation of catecholamine secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (chondroitin sulfate proteoglycan biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways resulting in the formation of chondroitin sulfate proteoglycan, any glycoprotein whose glycosaminoglycan units are chondroitin sulfate. Chondroitin sulfates are a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues; the repeat units consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate.") +AnnotationAssertion( "chondroitin sulfate proteoglycan anabolism") +AnnotationAssertion( "chondroitin sulfate proteoglycan biosynthesis") +AnnotationAssertion( "chondroitin sulfate proteoglycan formation") +AnnotationAssertion( "chondroitin sulfate proteoglycan synthesis") +AnnotationAssertion( "chondroitin sulphate proteoglycan biosynthesis") +AnnotationAssertion( "chondroitin sulphate proteoglycan biosynthetic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0050650") +AnnotationAssertion(rdfs:label "chondroitin sulfate proteoglycan biosynthetic process") +SubClassOf( ) +SubClassOf( ) + +# Class: (chondroitin sulfate proteoglycan metabolic process) + +AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways involving chondroitin sulfate proteoglycan, any glycoprotein whose glycosaminoglycan units are chondroitin sulfate. Chondroitin sulfates are a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues; the repeat units consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate.") +AnnotationAssertion( "chondroitin sulfate proteoglycan metabolism") +AnnotationAssertion( "chondroitin sulphate proteoglycan metabolic process") +AnnotationAssertion( "chondroitin sulphate proteoglycan metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0050654") +AnnotationAssertion(rdfs:label "chondroitin sulfate proteoglycan metabolic process") +SubClassOf( ) + +# Class: (nucleic acid transport) + +AnnotationAssertion(Annotation( "GOC:ai") Annotation( "ISBN:0198506732") "The directed movement of nucleic acids, single or double-stranded polynucleotides involved in the storage, transmission and transfer of genetic information, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0050657") +AnnotationAssertion(rdfs:label "nucleic acid transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (RNA transport) + +AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of RNA, ribonucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0050658") +AnnotationAssertion(rdfs:label "RNA transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of lymphocyte proliferation) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of lymphocyte proliferation.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0050670") +AnnotationAssertion(rdfs:label "regulation of lymphocyte proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of lymphocyte proliferation) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the rate or extent of lymphocyte proliferation.") +AnnotationAssertion( "up regulation of lymphocyte proliferation") +AnnotationAssertion( "up-regulation of lymphocyte proliferation") +AnnotationAssertion( "upregulation of lymphocyte proliferation") +AnnotationAssertion( "activation of lymphocyte proliferation") +AnnotationAssertion( "stimulation of lymphocyte proliferation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0050671") +AnnotationAssertion(rdfs:label "positive regulation of lymphocyte proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of lymphocyte proliferation) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents or reduces the rate or extent of lymphocyte proliferation.") +AnnotationAssertion( "down regulation of lymphocyte proliferation") +AnnotationAssertion( "down-regulation of lymphocyte proliferation") +AnnotationAssertion( "downregulation of lymphocyte proliferation") +AnnotationAssertion( "inhibition of lymphocyte proliferation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0050672") +AnnotationAssertion(rdfs:label "negative regulation of lymphocyte proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + # Class: (epithelial cell proliferation) AnnotationAssertion(Annotation( "ISBN:0721662544") "The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population. Epithelial cells make up the epithelium, the covering of internal and external surfaces of the body, including the lining of vessels and other small cavities. It consists of cells joined by small amounts of cementing substances.") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0050673") AnnotationAssertion(rdfs:label "epithelial cell proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (urothelial cell proliferation) + +AnnotationAssertion(Annotation( "ISBN:0721662544") "The multiplication or reproduction of urothelial cells, resulting in the expansion of a cell population. Urothelial cells make up a layer of transitional epithelium in the wall of the bladder, ureter, and renal pelvis, external to the lamina propria.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0050674") +AnnotationAssertion(rdfs:label "urothelial cell proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of urothelial cell proliferation) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of urothelial cell proliferation.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0050675") +AnnotationAssertion(rdfs:label "regulation of urothelial cell proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of urothelial cell proliferation) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents or reduces the rate or extent of urothelial cell proliferation.") +AnnotationAssertion( "down regulation of urothelial cell proliferation") +AnnotationAssertion( "down-regulation of urothelial cell proliferation") +AnnotationAssertion( "downregulation of urothelial cell proliferation") +AnnotationAssertion( "inhibition of urothelial cell proliferation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0050676") +AnnotationAssertion(rdfs:label "negative regulation of urothelial cell proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of urothelial cell proliferation) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the rate or extent of urothelial cell proliferation.") +AnnotationAssertion( "up regulation of urothelial cell proliferation") +AnnotationAssertion( "up-regulation of urothelial cell proliferation") +AnnotationAssertion( "upregulation of urothelial cell proliferation") +AnnotationAssertion( "activation of urothelial cell proliferation") +AnnotationAssertion( "stimulation of urothelial cell proliferation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0050677") +AnnotationAssertion(rdfs:label "positive regulation of urothelial cell proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of epithelial cell proliferation) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of epithelial cell proliferation.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0050678") +AnnotationAssertion(rdfs:label "regulation of epithelial cell proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (positive regulation of epithelial cell proliferation) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the rate or extent of epithelial cell proliferation.") +AnnotationAssertion( "up regulation of epithelial cell proliferation") +AnnotationAssertion( "up-regulation of epithelial cell proliferation") +AnnotationAssertion( "upregulation of epithelial cell proliferation") +AnnotationAssertion( "activation of epithelial cell proliferation") +AnnotationAssertion( "stimulation of epithelial cell proliferation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0050679") +AnnotationAssertion(rdfs:label "positive regulation of epithelial cell proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of epithelial cell proliferation) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents or reduces the rate or extent of epithelial cell proliferation.") +AnnotationAssertion( "down regulation of epithelial cell proliferation") +AnnotationAssertion( "down-regulation of epithelial cell proliferation") +AnnotationAssertion( "downregulation of epithelial cell proliferation") +AnnotationAssertion( "inhibition of epithelial cell proliferation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0050680") +AnnotationAssertion(rdfs:label "negative regulation of epithelial cell proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of protein secretion) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of the controlled release of a protein from a cell.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0050708") +AnnotationAssertion(rdfs:label "regulation of protein secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of protein secretion) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a protein from a cell.") +AnnotationAssertion( "down regulation of protein secretion") +AnnotationAssertion( "down-regulation of protein secretion") +AnnotationAssertion( "downregulation of protein secretion") +AnnotationAssertion( "inhibition of protein secretion") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0050709") +AnnotationAssertion(rdfs:label "negative regulation of protein secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of protein secretion) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of the controlled release of a protein from a cell.") +AnnotationAssertion( "up regulation of protein secretion") +AnnotationAssertion( "up-regulation of protein secretion") +AnnotationAssertion( "upregulation of protein secretion") +AnnotationAssertion( "activation of protein secretion") +AnnotationAssertion( "stimulation of protein secretion") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0050714") +AnnotationAssertion(rdfs:label "positive regulation of protein secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of inflammatory response) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of the inflammatory response, the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0050727") +AnnotationAssertion(rdfs:label "regulation of inflammatory response") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of inflammatory response) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of the inflammatory response.") +AnnotationAssertion( "GO:0030236") +AnnotationAssertion( "anti-inflammatory response") +AnnotationAssertion( "down regulation of inflammatory response") +AnnotationAssertion( "down-regulation of inflammatory response") +AnnotationAssertion( "downregulation of inflammatory response") +AnnotationAssertion( "inhibition of inflammatory response") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0050728") +AnnotationAssertion(rdfs:label "negative regulation of inflammatory response") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of inflammatory response) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of the inflammatory response.") +AnnotationAssertion( "up regulation of inflammatory response") +AnnotationAssertion( "up-regulation of inflammatory response") +AnnotationAssertion( "upregulation of inflammatory response") +AnnotationAssertion( "activation of inflammatory response") +AnnotationAssertion( "stimulation of inflammatory response") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0050729") +AnnotationAssertion(rdfs:label "positive regulation of inflammatory response") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of peptidyl-tyrosine phosphorylation) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0050730") +AnnotationAssertion(rdfs:label "regulation of peptidyl-tyrosine phosphorylation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of peptidyl-tyrosine phosphorylation) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine.") +AnnotationAssertion( "up regulation of peptidyl-tyrosine phosphorylation") +AnnotationAssertion( "up-regulation of peptidyl-tyrosine phosphorylation") +AnnotationAssertion( "upregulation of peptidyl-tyrosine phosphorylation") +AnnotationAssertion( "activation of peptidyl-tyrosine phosphorylation") +AnnotationAssertion( "stimulation of peptidyl-tyrosine phosphorylation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0050731") +AnnotationAssertion(rdfs:label "positive regulation of peptidyl-tyrosine phosphorylation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of peptidyl-tyrosine phosphorylation) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine.") +AnnotationAssertion( "down regulation of peptidyl-tyrosine phosphorylation") +AnnotationAssertion( "down-regulation of peptidyl-tyrosine phosphorylation") +AnnotationAssertion( "downregulation of peptidyl-tyrosine phosphorylation") +AnnotationAssertion( "inhibition of peptidyl-tyrosine phosphorylation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0050732") +AnnotationAssertion(rdfs:label "negative regulation of peptidyl-tyrosine phosphorylation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of lipoprotein metabolic process) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving lipoproteins, any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids.") +AnnotationAssertion( "regulation of lipoprotein metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0050746") +AnnotationAssertion(rdfs:label "regulation of lipoprotein metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (positive regulation of lipoprotein metabolic process) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving lipoproteins, any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids.") +AnnotationAssertion( "positive regulation of lipoprotein metabolism") +AnnotationAssertion( "up regulation of lipoprotein metabolic process") +AnnotationAssertion( "up-regulation of lipoprotein metabolic process") +AnnotationAssertion( "upregulation of lipoprotein metabolic process") +AnnotationAssertion( "activation of lipoprotein metabolic process") +AnnotationAssertion( "stimulation of lipoprotein metabolic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0050747") +AnnotationAssertion(rdfs:label "positive regulation of lipoprotein metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (negative regulation of lipoprotein metabolic process) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving lipoproteins, any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids.") +AnnotationAssertion( "down regulation of lipoprotein metabolic process") +AnnotationAssertion( "down-regulation of lipoprotein metabolic process") +AnnotationAssertion( "downregulation of lipoprotein metabolic process") +AnnotationAssertion( "negative regulation of lipoprotein metabolism") +AnnotationAssertion( "inhibition of lipoprotein metabolic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0050748") +AnnotationAssertion(rdfs:label "negative regulation of lipoprotein metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of phagocytosis) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of phagocytosis, the process in which phagocytes engulf external particulate material.") +AnnotationAssertion( ) +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0050764") +AnnotationAssertion(rdfs:label "regulation of phagocytosis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) +SubClassOf( ObjectSomeValuesFrom( )) +DisjointClasses( ObjectSomeValuesFrom( )) + +# Class: (negative regulation of phagocytosis) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of phagocytosis.") +AnnotationAssertion( "down regulation of phagocytosis") +AnnotationAssertion( "down-regulation of phagocytosis") +AnnotationAssertion( "downregulation of phagocytosis") +AnnotationAssertion( "inhibition of phagocytosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0050765") +AnnotationAssertion(rdfs:label "negative regulation of phagocytosis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of phagocytosis) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of phagocytosis.") +AnnotationAssertion( "up regulation of phagocytosis") +AnnotationAssertion( "up-regulation of phagocytosis") +AnnotationAssertion( "upregulation of phagocytosis") +AnnotationAssertion( "activation of phagocytosis") +AnnotationAssertion( "stimulation of phagocytosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0050766") +AnnotationAssertion(rdfs:label "positive regulation of phagocytosis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of neurogenesis) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of neurogenesis, the generation of cells in the nervous system.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0050767") +AnnotationAssertion(rdfs:label "regulation of neurogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (negative regulation of neurogenesis) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of neurogenesis, the generation of cells within the nervous system.") +AnnotationAssertion( "down regulation of neurogenesis") +AnnotationAssertion( "down-regulation of neurogenesis") +AnnotationAssertion( "downregulation of neurogenesis") +AnnotationAssertion( "inhibition of neurogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0050768") +AnnotationAssertion(rdfs:label "negative regulation of neurogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of neurogenesis) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of neurogenesis, the generation of cells within the nervous system.") +AnnotationAssertion( "up regulation of neurogenesis") +AnnotationAssertion( "up-regulation of neurogenesis") +AnnotationAssertion( "upregulation of neurogenesis") +AnnotationAssertion( "activation of neurogenesis") +AnnotationAssertion( "stimulation of neurogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0050769") +AnnotationAssertion(rdfs:label "positive regulation of neurogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of axonogenesis) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of axonogenesis, the generation of an axon, the long process of a neuron.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0050770") +AnnotationAssertion(rdfs:label "regulation of axonogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (negative regulation of axonogenesis) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of axonogenesis.") +AnnotationAssertion( "down regulation of axonogenesis") +AnnotationAssertion( "down-regulation of axonogenesis") +AnnotationAssertion( "downregulation of axonogenesis") +AnnotationAssertion( "inhibition of axonogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0050771") +AnnotationAssertion(rdfs:label "negative regulation of axonogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (positive regulation of axonogenesis) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of axonogenesis.") +AnnotationAssertion( "up regulation of axonogenesis") +AnnotationAssertion( "up-regulation of axonogenesis") +AnnotationAssertion( "upregulation of axonogenesis") +AnnotationAssertion( "activation of axonogenesis") +AnnotationAssertion( "stimulation of axonogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0050772") +AnnotationAssertion(rdfs:label "positive regulation of axonogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of dendrite development) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of dendrite development.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0050773") +AnnotationAssertion(rdfs:label "regulation of dendrite development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of dendrite morphogenesis) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of dendrite morphogenesis.") +AnnotationAssertion( "down regulation of dendrite morphogenesis") +AnnotationAssertion( "down-regulation of dendrite morphogenesis") +AnnotationAssertion( "downregulation of dendrite morphogenesis") +AnnotationAssertion( "inhibition of dendrite morphogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0050774") +AnnotationAssertion(rdfs:label "negative regulation of dendrite morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (positive regulation of dendrite morphogenesis) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of dendrite morphogenesis.") +AnnotationAssertion( "up regulation of dendrite morphogenesis") +AnnotationAssertion( "up-regulation of dendrite morphogenesis") +AnnotationAssertion( "upregulation of dendrite morphogenesis") +AnnotationAssertion( "activation of dendrite morphogenesis") +AnnotationAssertion( "stimulation of dendrite morphogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0050775") +AnnotationAssertion(rdfs:label "positive regulation of dendrite morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (regulation of immune response) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0050776") +AnnotationAssertion(rdfs:label "regulation of immune response") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of immune response) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.") +AnnotationAssertion( "down regulation of immune response") +AnnotationAssertion( "down-regulation of immune response") +AnnotationAssertion( "downregulation of immune response") +AnnotationAssertion( "inhibition of immune response") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0050777") +AnnotationAssertion(rdfs:label "negative regulation of immune response") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of immune response) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.") +AnnotationAssertion( "up regulation of immune response") +AnnotationAssertion( "up-regulation of immune response") +AnnotationAssertion( "upregulation of immune response") +AnnotationAssertion( "stimulation of immune response") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0050778") +AnnotationAssertion(rdfs:label "positive regulation of immune response") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + # Class: (regulation of biological process) AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.") @@ -38751,14 +91691,29 @@ AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "regulation of biological process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (regulation of catalytic activity) + +AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:ebc") Annotation( "GOC:vw") "Any process that modulates the activity of an enzyme.") +AnnotationAssertion( "GO:0048552") +AnnotationAssertion( "regulation of enzyme activity") +AnnotationAssertion( "regulation of metalloenzyme activity") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0050790") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "regulation of catalytic activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (regulation of developmental process) AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of development, the biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0050793") AnnotationAssertion(rdfs:label "regulation of developmental process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) # Class: (regulation of cellular process) @@ -38770,6 +91725,7 @@ AnnotationAssertion( "GO:0050794") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "regulation of cellular process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (regulation of behavior) @@ -38778,8 +91734,134 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0050795") AnnotationAssertion(rdfs:label "regulation of behavior") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (regulation of insulin secretion) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of the regulated release of insulin.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0050796") +AnnotationAssertion(rdfs:label "regulation of insulin secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (monoatomic ion homeostasis) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process involved in the maintenance of an internal steady state of monoatomic ions within an organism or cell. Monatomic ions (also called simple ions) are ions consisting of exactly one atom.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/24455"^^xsd:anyURI) +AnnotationAssertion( "GO:2000021") +AnnotationAssertion( "ion homeostasis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "electrolyte homeostasis") +AnnotationAssertion( "negative regulation of crystal formation") +AnnotationAssertion( "regulation of ion homeostasis") +AnnotationAssertion( "GO:0050801") +AnnotationAssertion(rdfs:label "monoatomic ion homeostasis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (circadian sleep/wake cycle, sleep) + +AnnotationAssertion(Annotation( "GOC:ai") "The part of the circadian sleep/wake cycle where the organism is asleep.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0050802") +AnnotationAssertion(rdfs:label "circadian sleep/wake cycle, sleep") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of synapse structure or activity) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the physical form or the activity of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell).") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0050803") +AnnotationAssertion(rdfs:label "regulation of synapse structure or activity") +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectAllValuesFrom( )) + +# Class: (modulation of chemical synaptic transmission) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency or amplitude of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse. Amplitude, in this case, refers to the change in postsynaptic membrane potential due to a single instance of synaptic transmission.") +AnnotationAssertion( "modulation of synaptic transmission") +AnnotationAssertion( "regulation of chemical synaptic transmission") +AnnotationAssertion( "regulation of synaptic transmission") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0050804") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "modulation of chemical synaptic transmission") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (negative regulation of synaptic transmission) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse.") +AnnotationAssertion( "down regulation of synaptic transmission") +AnnotationAssertion( "down-regulation of synaptic transmission") +AnnotationAssertion( "downregulation of synaptic transmission") +AnnotationAssertion( "inhibition of synaptic transmission") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0050805") +AnnotationAssertion(rdfs:label "negative regulation of synaptic transmission") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of synaptic transmission) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse.") +AnnotationAssertion( "up regulation of synaptic transmission") +AnnotationAssertion( "up-regulation of synaptic transmission") +AnnotationAssertion( "upregulation of synaptic transmission") +AnnotationAssertion( "activation of synaptic transmission") +AnnotationAssertion( "stimulation of synaptic transmission") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0050806") +AnnotationAssertion(rdfs:label "positive regulation of synaptic transmission") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of synapse organization) + +AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the physical form of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell).") +AnnotationAssertion(Annotation( "GOC:mah") "regulation of synapse organisation") +AnnotationAssertion( "regulation of synapse structure") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:mah") "regulation of synapse organization and biogenesis") +AnnotationAssertion( "GO:0050807") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "regulation of synapse organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (synapse organization) + +AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:pr") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell).") +AnnotationAssertion( "synapse organisation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:aruk") "synapse development") +AnnotationAssertion(Annotation( "GOC:BHF") "synapse morphogenesis") +AnnotationAssertion(Annotation( "GOC:mah") "synapse organization and biogenesis") +AnnotationAssertion( "GO:0050808") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "synapse organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of steroid biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.") +AnnotationAssertion( "regulation of steroid anabolism") +AnnotationAssertion( "regulation of steroid biosynthesis") +AnnotationAssertion( "regulation of steroid formation") +AnnotationAssertion( "regulation of steroid synthesis") +AnnotationAssertion( "regulation of steroidogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0050810") +AnnotationAssertion(rdfs:label "regulation of steroid biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + # Class: (coagulation) AnnotationAssertion(Annotation( "ISBN:0198506732") "The process in which a fluid solution, or part of it, changes into a solid or semisolid mass.") @@ -38832,6 +91914,19 @@ EquivalentClasses( ObjectIntersection SubClassOf( ) SubClassOf( ) +# Class: (ice binding) + +AnnotationAssertion(Annotation( "GOC:curators") "Binding to ice, water reduced to the solid state by cold temperature. It is a white or transparent colorless substance, crystalline, brittle, and viscoidal.") +AnnotationAssertion( "ice crystal binding") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "antifreeze activity") +AnnotationAssertion( "ice nucleation activity") +AnnotationAssertion( "ice nucleation inhibitor activity") +AnnotationAssertion( "GO:0050825") +AnnotationAssertion(rdfs:label "ice binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + # Class: (defense response to fungus) AnnotationAssertion(Annotation( "GOC:ai") "Reactions triggered in response to the presence of a fungus that act to protect the cell or organism.") @@ -39050,6 +92145,7 @@ AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "nervous system process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectAllValuesFrom( )) @@ -39130,6 +92226,7 @@ AnnotationAssertion( "GOC:dph") Annotation( "GOC:tb") "body fluid osmoregulation") AnnotationAssertion( "GO:0050891") AnnotationAssertion(rdfs:label "multicellular organismal-level water homeostasis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) # Class: (response to stimulus) @@ -39149,6 +92246,23 @@ AnnotationAssertion(rdfs:comment "No AnnotationAssertion(rdfs:label "response to stimulus") SubClassOf( ) +# Class: (leukocyte migration) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") Annotation( "PMID:14680625") Annotation( "PMID:14708592") Annotation( "PMID:7507411") Annotation( "PMID:8600538") "The movement of a leukocyte within or between different tissues and organs of the body.") +AnnotationAssertion( "immune cell migration") +AnnotationAssertion( "immune cell trafficking") +AnnotationAssertion( "leucocyte migration") +AnnotationAssertion( "leucocyte trafficking") +AnnotationAssertion( "leukocyte trafficking") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0050900") +AnnotationAssertion(rdfs:label "leukocyte migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectAllValuesFrom( )) + # Class: (neuromuscular process) AnnotationAssertion(Annotation( "GOC:ai") "Any process pertaining to the functions of the nervous and muscular systems of an organism.") @@ -39170,6 +92284,7 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0050906") AnnotationAssertion(rdfs:label "detection of stimulus involved in sensory perception") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) # Class: (detection of chemical stimulus involved in sensory perception) @@ -39184,6 +92299,7 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0050907") AnnotationAssertion(rdfs:label "detection of chemical stimulus involved in sensory perception") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) @@ -39201,9 +92317,23 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0050908") AnnotationAssertion(rdfs:label "detection of light stimulus involved in visual perception") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) +# Class: (sensory perception of taste) + +AnnotationAssertion(Annotation( "GOC:ai") "The series of events required for an organism to receive a gustatory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Gustation involves the direct detection of chemical composition, usually through contact with chemoreceptor cells. This is a neurological process.") +AnnotationAssertion( "Wikipedia:Taste") +AnnotationAssertion( "gustation") +AnnotationAssertion( "sense of taste") +AnnotationAssertion( "taste") +AnnotationAssertion( "taste perception") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0050909") +AnnotationAssertion(rdfs:label "sensory perception of taste") +SubClassOf( ) + # Class: (detection of mechanical stimulus involved in sensory perception of sound) AnnotationAssertion(Annotation( "GOC:ai") "The series of events involved in the perception of sound vibration in which the vibration is received and converted into a molecular signal.") @@ -39220,6 +92350,7 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0050910") AnnotationAssertion(rdfs:label "detection of mechanical stimulus involved in sensory perception of sound") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) @@ -39238,6 +92369,7 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0050911") AnnotationAssertion(rdfs:label "detection of chemical stimulus involved in sensory perception of smell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) # Class: (detection of chemical stimulus involved in sensory perception of taste) @@ -39254,8 +92386,95 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0050912") AnnotationAssertion(rdfs:label "detection of chemical stimulus involved in sensory perception of taste") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (regulation of chemotaxis) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0050920") +AnnotationAssertion(rdfs:label "regulation of chemotaxis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (positive regulation of chemotaxis) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient.") +AnnotationAssertion( "up regulation of chemotaxis") +AnnotationAssertion( "up-regulation of chemotaxis") +AnnotationAssertion( "upregulation of chemotaxis") +AnnotationAssertion( "activation of chemotaxis") +AnnotationAssertion( "stimulation of chemotaxis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0050921") +AnnotationAssertion(rdfs:label "positive regulation of chemotaxis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (negative regulation of chemotaxis) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient.") +AnnotationAssertion( "down regulation of chemotaxis") +AnnotationAssertion( "down-regulation of chemotaxis") +AnnotationAssertion( "downregulation of chemotaxis") +AnnotationAssertion( "inhibition of chemotaxis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0050922") +AnnotationAssertion(rdfs:label "negative regulation of chemotaxis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (pigment cell differentiation) + +AnnotationAssertion(Annotation( "GOC:dgh") "The process in which a relatively unspecialized cell acquires the specialized features of a pigmented cell, such as a melanocyte.") +AnnotationAssertion( "GO:0043357") +AnnotationAssertion( "GO:0043358") +AnnotationAssertion( "chromatophore differentiation") +AnnotationAssertion( "pigmented cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0050931") +AnnotationAssertion(rdfs:comment "Note that the chromatophore mentioned here is distinct from the pigment bearing structure found in certain photosynthetic bacteria and cyanobacteria. It is also different from the plant chromoplast, which is also sometimes called a chromatophore.") +AnnotationAssertion(rdfs:label "pigment cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (regulation of pigment cell differentiation) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of pigmented cell differentiation.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0050932") +AnnotationAssertion(rdfs:label "regulation of pigment cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of pigment cell differentiation) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of pigment cell differentiation.") +AnnotationAssertion( "down regulation of pigment cell differentiation") +AnnotationAssertion( "down-regulation of pigment cell differentiation") +AnnotationAssertion( "downregulation of pigment cell differentiation") +AnnotationAssertion( "inhibition of pigment cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0050941") +AnnotationAssertion(rdfs:label "negative regulation of pigment cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (positive regulation of pigment cell differentiation) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of pigment cell differentiation.") +AnnotationAssertion( "up regulation of pigment cell differentiation") +AnnotationAssertion( "up-regulation of pigment cell differentiation") +AnnotationAssertion( "upregulation of pigment cell differentiation") +AnnotationAssertion( "activation of pigment cell differentiation") +AnnotationAssertion( "stimulation of pigment cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0050942") +AnnotationAssertion(rdfs:label "positive regulation of pigment cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + # Class: (sensory perception of temperature stimulus) AnnotationAssertion(Annotation( "GOC:ai") "The series of events required for an organism to receive a sensory temperature stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.") @@ -39292,6 +92511,17 @@ AnnotationAssertion( "sensory perception of mechanical stimulus") SubClassOf( ) +# Class: (electroception) + +AnnotationAssertion(Annotation( "GOC:ai") Annotation( "PMID:10210663") Annotation( "Wikipedia:Electroreception") "The series of events required for an organism to receive an electrical stimulus, convert it to a molecular signal, and recognize and characterize the signal. Many fish possess an electroception sense; for example, the electric eel uses low voltage pulses of electricity for navigation and prey location.") +AnnotationAssertion( "Wikipedia:Electroreception") +AnnotationAssertion( "electroception sense") +AnnotationAssertion( "electroceptive sense") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0050956") +AnnotationAssertion(rdfs:label "electroception") +SubClassOf( ) + # Class: (equilibrioception) AnnotationAssertion(Annotation( "http://www.medterms.com") "The series of events required for an organism to receive an orientational stimulus, convert it to a molecular signal, and recognize and characterize the signal. Equilibrioception refers to a combination of processes by which an organism can perceive its orientation with respect to gravity. In animals, stimuli come from labyrinth system of the inner ears, monitoring the direction of motion; visual stimuli, with information on orientation and motion; pressure receptors, which tell the organism which body surfaces are in contact with the ground; and proprioceptive cues, which report which parts of the body are in motion.") @@ -39344,6 +92574,7 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0050961") AnnotationAssertion(rdfs:label "detection of temperature stimulus involved in sensory perception") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) @@ -39360,6 +92591,7 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0050962") AnnotationAssertion(rdfs:label "detection of light stimulus involved in sensory perception") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) @@ -39376,6 +92608,7 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0050963") AnnotationAssertion(rdfs:label "detection of electrical stimulus involved in sensory perception") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) @@ -39393,8 +92626,28 @@ AnnotationAssertion( "sensory transduction of electrical stimulus during electroception") AnnotationAssertion( "GO:0050964") AnnotationAssertion(rdfs:label "detection of electrical stimulus involved in electroception") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (detection of temperature stimulus involved in sensory perception of pain) + +AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:dos") "The series of events involved in the perception of pain in which a temperature stimulus is received and converted into a molecular signal.") +AnnotationAssertion( "perception of pain, detection of temperature stimulus") +AnnotationAssertion( "perception of pain, sensory detection of temperature stimulus") +AnnotationAssertion( "perception of pain, sensory transduction of temperature stimulus") +AnnotationAssertion( "sensory detection of temperature stimulus during perception of pain") +AnnotationAssertion( "sensory detection of thermal stimulus during sensory perception of pain") +AnnotationAssertion( "sensory perception of pain, sensory detection of thermal stimulus") +AnnotationAssertion( "sensory perception of pain, sensory transduction of thermal stimulus") +AnnotationAssertion( "sensory transduction of temperature stimulus during perception of pain") +AnnotationAssertion( "sensory transduction of thermal stimulus during sensory perception of pain") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:pr") "thermal nociception") +AnnotationAssertion( "GO:0050965") +AnnotationAssertion(rdfs:label "detection of temperature stimulus involved in sensory perception of pain") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + # Class: (detection of mechanical stimulus involved in sensory perception of pain) AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:dos") "The series of events involved in the perception of pain in which a mechanical stimulus is received and converted into a molecular signal.") @@ -39407,8 +92660,53 @@ AnnotationAssertion( "GOC:pr") "mechanical nociception") AnnotationAssertion( "GO:0050966") AnnotationAssertion(rdfs:label "detection of mechanical stimulus involved in sensory perception of pain") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (detection of electrical stimulus involved in sensory perception of pain) + +AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:dos") Annotation( "GOC:dph") Annotation( "GOC:tb") "The series of events that contribute to the perception of pain in which an electrical stimulus is received and converted into a molecular signal.") +AnnotationAssertion( "perception of pain, detection of electrical stimulus") +AnnotationAssertion( "perception of pain, sensory detection of electrical stimulus") +AnnotationAssertion( "perception of pain, sensory transduction of electrical stimulus") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "detection of electrical stimulus during sensory perception of pain") +AnnotationAssertion( "sensory detection of electrical stimulus during perception of pain") +AnnotationAssertion( "sensory transduction of electrical stimulus during perception of pain") +AnnotationAssertion( "GO:0050967") +AnnotationAssertion(rdfs:label "detection of electrical stimulus involved in sensory perception of pain") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (detection of chemical stimulus involved in sensory perception of pain) + +AnnotationAssertion(Annotation( "GOC:ai") "The series of events involved in the perception of pain in which a chemical stimulus is received and converted into a molecular signal.") +AnnotationAssertion( "perception of pain, detection of chemical stimulus") +AnnotationAssertion( "perception of pain, sensory detection of chemical stimulus") +AnnotationAssertion( "perception of pain, sensory transduction of chemical stimulus") +AnnotationAssertion( "sensory detection of chemical stimulus during perception of pain") +AnnotationAssertion( "sensory transduction of chemical stimulus during perception of pain") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:pr") "chemical nociception") +AnnotationAssertion( "GO:0050968") +AnnotationAssertion(rdfs:label "detection of chemical stimulus involved in sensory perception of pain") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (detection of mechanical stimulus involved in echolocation) + +AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:dos") "The series of events involved in echolocation in which a mechanical stimulus is received and converted into a molecular signal. The stimulus is in the form of a reflected sound wave (an echo), which the organism uses to determine the distance to the object that reflected the sound wave.") +AnnotationAssertion( "echolocation, detection of mechanical stimulus") +AnnotationAssertion( "echolocation, sensory detection of mechanical stimulus") +AnnotationAssertion( "echolocation, sensory transduction of mechanical stimulus") +AnnotationAssertion( "sensory detection of mechanical stimulus during echolocation") +AnnotationAssertion( "sensory transduction of mechanical stimulus during echolocation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0050972") +AnnotationAssertion(rdfs:label "detection of mechanical stimulus involved in echolocation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + # Class: (detection of mechanical stimulus involved in equilibrioception) AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:dos") "The series of events involved in equilibrioception in which a mechanical stimulus is received and converted into a molecular signal. During equilibrioception, mechanical stimuli may be in the form of input from pressure receptors or from the labyrinth system of the inner ears.") @@ -39420,6 +92718,7 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0050973") AnnotationAssertion(rdfs:label "detection of mechanical stimulus involved in equilibrioception") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) # Class: (detection of mechanical stimulus involved in sensory perception) @@ -39434,6 +92733,7 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0050974") AnnotationAssertion(rdfs:label "detection of mechanical stimulus involved in sensory perception") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) @@ -39463,6 +92763,7 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0050976") AnnotationAssertion(rdfs:label "detection of mechanical stimulus involved in sensory perception of touch") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) # Class: (detection of electrical stimulus) @@ -39533,7 +92834,7 @@ AnnotationAssertion( "molecular_function") AnnotationAssertion( "GO:0050997") AnnotationAssertion(rdfs:label "quaternary ammonium group binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (actin filament bundle assembly) @@ -39590,8 +92891,38 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:0051046") AnnotationAssertion(rdfs:label "regulation of secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (positive regulation of secretion) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of the controlled release of a substance from a cell or a tissue.") +AnnotationAssertion( "up regulation of secretion") +AnnotationAssertion( "up-regulation of secretion") +AnnotationAssertion( "upregulation of secretion") +AnnotationAssertion( "activation of secretion") +AnnotationAssertion( "stimulation of secretion") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051047") +AnnotationAssertion(rdfs:label "positive regulation of secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of secretion) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a substance from a cell or a tissue.") +AnnotationAssertion( "down regulation of secretion") +AnnotationAssertion( "down-regulation of secretion") +AnnotationAssertion( "downregulation of secretion") +AnnotationAssertion( "inhibition of secretion") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051048") +AnnotationAssertion(rdfs:label "negative regulation of secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + # Class: (regulation of transport) AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") @@ -39599,8 +92930,142 @@ AnnotationAssertion( "GO:0051049") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "regulation of transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (positive regulation of transport) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion( "up regulation of transport") +AnnotationAssertion( "up-regulation of transport") +AnnotationAssertion( "upregulation of transport") +AnnotationAssertion( "activation of transport") +AnnotationAssertion( "stimulation of transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051050") +AnnotationAssertion(rdfs:label "positive regulation of transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of transport) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion( "down regulation of transport") +AnnotationAssertion( "down-regulation of transport") +AnnotationAssertion( "downregulation of transport") +AnnotationAssertion( "inhibition of transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051051") +AnnotationAssertion(rdfs:label "negative regulation of transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of DNA metabolic process) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving DNA.") +AnnotationAssertion( "regulation of DNA metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051052") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "regulation of DNA metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of DNA metabolic process) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving DNA.") +AnnotationAssertion( "down regulation of DNA metabolic process") +AnnotationAssertion( "down-regulation of DNA metabolic process") +AnnotationAssertion( "downregulation of DNA metabolic process") +AnnotationAssertion( "negative regulation of DNA metabolism") +AnnotationAssertion( "inhibition of DNA metabolic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051053") +AnnotationAssertion(rdfs:label "negative regulation of DNA metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of DNA metabolic process) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving DNA.") +AnnotationAssertion( "positive regulation of DNA metabolism") +AnnotationAssertion( "up regulation of DNA metabolic process") +AnnotationAssertion( "up-regulation of DNA metabolic process") +AnnotationAssertion( "upregulation of DNA metabolic process") +AnnotationAssertion( "activation of DNA metabolic process") +AnnotationAssertion( "stimulation of DNA metabolic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051054") +AnnotationAssertion(rdfs:label "positive regulation of DNA metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of lipid biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids.") +AnnotationAssertion( "down regulation of lipid biosynthetic process") +AnnotationAssertion( "down-regulation of lipid biosynthetic process") +AnnotationAssertion( "downregulation of lipid biosynthetic process") +AnnotationAssertion( "negative regulation of lipid anabolism") +AnnotationAssertion( "negative regulation of lipid biosynthesis") +AnnotationAssertion( "negative regulation of lipid formation") +AnnotationAssertion( "negative regulation of lipid synthesis") +AnnotationAssertion(Annotation( "GOC:sl") "negative regulation of lipogenesis") +AnnotationAssertion( "inhibition of lipid biosynthetic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051055") +AnnotationAssertion(rdfs:label "negative regulation of lipid biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (NF-kappaB binding) + +AnnotationAssertion(Annotation( "GOC:ai") "Binding to NF-kappaB, a transcription factor for eukaryotic RNA polymerase II promoters.") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0051059") +AnnotationAssertion(rdfs:label "NF-kappaB binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (meiotic nuclear membrane disassembly) + +AnnotationAssertion(Annotation( "GOC:bf") "The cell cycle process in which the controlled breakdown of the nuclear membranes during meiotic cell division occurs.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "meiotic nuclear envelope breakdown") +AnnotationAssertion( "meiotic nuclear envelope catabolism") +AnnotationAssertion( "meiotic nuclear envelope degradation") +AnnotationAssertion( "meiotic nuclear envelope disassembly") +AnnotationAssertion( "GO:0051078") +AnnotationAssertion(rdfs:label "meiotic nuclear membrane disassembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (meiosis II nuclear membrane disassembly) + +AnnotationAssertion(Annotation( "GOC:bf") "The controlled breakdown of the nuclear membranes during the second division of meiosis.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "meiosis II nuclear envelope breakdown") +AnnotationAssertion( "meiosis II nuclear envelope catabolism") +AnnotationAssertion( "meiosis II nuclear envelope degradation") +AnnotationAssertion( "meiosis II nuclear envelope disassembly") +AnnotationAssertion( "GO:0051080") +AnnotationAssertion(rdfs:label "meiosis II nuclear membrane disassembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (nuclear membrane disassembly) + +AnnotationAssertion(Annotation( "GOC:ai") "The controlled breakdown of the nuclear membranes, for example during cellular division.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "nuclear envelope breakdown") +AnnotationAssertion( "nuclear envelope catabolism") +AnnotationAssertion( "nuclear envelope degradation") +AnnotationAssertion( "nuclear envelope disassembly") +AnnotationAssertion( "GO:0051081") +AnnotationAssertion(rdfs:label "nuclear membrane disassembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (negative regulation of developmental process) AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents or reduces the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).") @@ -39611,9 +93076,369 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0051093") AnnotationAssertion(rdfs:label "negative regulation of developmental process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) +# Class: (positive regulation of developmental process) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).") +AnnotationAssertion( "up regulation of developmental process") +AnnotationAssertion( "up-regulation of developmental process") +AnnotationAssertion( "upregulation of developmental process") +AnnotationAssertion( "activation of developmental process") +AnnotationAssertion( "stimulation of developmental process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051094") +AnnotationAssertion(rdfs:label "positive regulation of developmental process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of binding) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051098") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "regulation of binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of binding) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule.") +AnnotationAssertion( "up regulation of binding") +AnnotationAssertion( "up-regulation of binding") +AnnotationAssertion( "upregulation of binding") +AnnotationAssertion( "activation of binding") +AnnotationAssertion( "stimulation of binding") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051099") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "positive regulation of binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of binding) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops or reduces the rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule.") +AnnotationAssertion( "down regulation of binding") +AnnotationAssertion( "down-regulation of binding") +AnnotationAssertion( "downregulation of binding") +AnnotationAssertion( "inhibition of binding") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051100") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "negative regulation of binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of DNA binding) + +AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid).") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051101") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "regulation of DNA binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (sugar transmembrane transporter activity) + +AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:mtg_transport") Annotation( "ISBN:0815340729") "Enables the transfer of a sugar from one side of a membrane to the other. A sugar is any member of a class of sweet, water-soluble, crystallizable carbohydrates, which are the monosaccharides and smaller oligosaccharides.") +AnnotationAssertion(Annotation(rdfs:label "GLUT7 and GLUT11 transport glucose and fructose") "Reactome:R-HSA-428779") +AnnotationAssertion(Annotation(rdfs:label "SLC45A3 transports Glc from extracellular region to cytosol") "Reactome:R-HSA-8875902") +AnnotationAssertion(Annotation(rdfs:label "SLC50A1 transports Glc from cytosol to extracellular region") "Reactome:R-HSA-8876319") +AnnotationAssertion( "sugar/polyol channel activity") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0051119") +AnnotationAssertion(rdfs:label "sugar transmembrane transporter activity") +SubClassOf( ) + +# Class: (regulation of cellular component organization) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.") +AnnotationAssertion( "regulation of cellular component organisation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:mah") "regulation of cell organisation") +AnnotationAssertion(Annotation( "GOC:mah") "regulation of cell organization") +AnnotationAssertion(Annotation( "GOC:mah") "regulation of cellular component organization and biogenesis") +AnnotationAssertion( "GO:0051128") +AnnotationAssertion(rdfs:label "regulation of cellular component organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of cellular component organization) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.") +AnnotationAssertion( "down regulation of cell organization") +AnnotationAssertion( "down-regulation of cell organization") +AnnotationAssertion( "downregulation of cell organization") +AnnotationAssertion( "inhibition of cell organization") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:mah") "negative regulation of cell organisation") +AnnotationAssertion(Annotation( "GOC:mah") "negative regulation of cellular component organization and biogenesis") +AnnotationAssertion( "GO:0051129") +AnnotationAssertion(rdfs:label "negative regulation of cellular component organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of cellular component organization) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.") +AnnotationAssertion( "positive regulation of cell organisation") +AnnotationAssertion( "up regulation of cell organization") +AnnotationAssertion( "up-regulation of cell organization") +AnnotationAssertion( "upregulation of cell organization") +AnnotationAssertion( "activation of cell organization") +AnnotationAssertion( "stimulation of cell organization") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:mah") "positive regulation of cellular component organization and biogenesis") +AnnotationAssertion( "GO:0051130") +AnnotationAssertion(rdfs:label "positive regulation of cellular component organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (smooth muscle cell differentiation) + +AnnotationAssertion(Annotation( "CL:0000192") Annotation( "GOC:ai") "The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell; smooth muscle lacks transverse striations in its constituent fibers and are almost always involuntary.") +AnnotationAssertion( "nonstriated muscle cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051145") +AnnotationAssertion(rdfs:label "smooth muscle cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (striated muscle cell differentiation) + +AnnotationAssertion(Annotation( "CL:0000737") Annotation( "GOC:ai") "The process in which a relatively unspecialized cell acquires specialized features of a striated muscle cell; striated muscle fibers are divided by transverse bands into striations, and cardiac and voluntary muscle are types of striated muscle.") +AnnotationAssertion( "voluntary muscle cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051146") +AnnotationAssertion(rdfs:label "striated muscle cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of muscle cell differentiation) + +AnnotationAssertion(Annotation( "CL:0000187") Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of muscle cell differentiation.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051147") +AnnotationAssertion(rdfs:label "regulation of muscle cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of muscle cell differentiation) + +AnnotationAssertion(Annotation( "CL:0000187") Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of muscle cell differentiation.") +AnnotationAssertion( "down regulation of muscle cell differentiation") +AnnotationAssertion( "down-regulation of muscle cell differentiation") +AnnotationAssertion( "downregulation of muscle cell differentiation") +AnnotationAssertion( "inhibition of muscle cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051148") +AnnotationAssertion(rdfs:label "negative regulation of muscle cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of muscle cell differentiation) + +AnnotationAssertion(Annotation( "CL:0000187") Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of muscle cell differentiation.") +AnnotationAssertion( "up regulation of muscle cell differentiation") +AnnotationAssertion( "up-regulation of muscle cell differentiation") +AnnotationAssertion( "upregulation of muscle cell differentiation") +AnnotationAssertion( "activation of muscle cell differentiation") +AnnotationAssertion( "stimulation of muscle cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051149") +AnnotationAssertion(rdfs:label "positive regulation of muscle cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of smooth muscle cell differentiation) + +AnnotationAssertion(Annotation( "CL:0000192") Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of smooth muscle cell differentiation.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051150") +AnnotationAssertion(rdfs:label "regulation of smooth muscle cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of smooth muscle cell differentiation) + +AnnotationAssertion(Annotation( "CL:0000192") Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle cell differentiation.") +AnnotationAssertion( "down regulation of smooth muscle cell differentiation") +AnnotationAssertion( "down-regulation of smooth muscle cell differentiation") +AnnotationAssertion( "downregulation of smooth muscle cell differentiation") +AnnotationAssertion( "inhibition of smooth muscle cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051151") +AnnotationAssertion(rdfs:label "negative regulation of smooth muscle cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of smooth muscle cell differentiation) + +AnnotationAssertion(Annotation( "CL:0000192") Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of smooth muscle cell differentiation.") +AnnotationAssertion( "up regulation of smooth muscle cell differentiation") +AnnotationAssertion( "up-regulation of smooth muscle cell differentiation") +AnnotationAssertion( "upregulation of smooth muscle cell differentiation") +AnnotationAssertion( "activation of smooth muscle cell differentiation") +AnnotationAssertion( "stimulation of smooth muscle cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051152") +AnnotationAssertion(rdfs:label "positive regulation of smooth muscle cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of striated muscle cell differentiation) + +AnnotationAssertion(Annotation( "CL:0000737") Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of striated muscle cell differentiation.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051153") +AnnotationAssertion(rdfs:label "regulation of striated muscle cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of striated muscle cell differentiation) + +AnnotationAssertion(Annotation( "CL:0000737") Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle cell differentiation.") +AnnotationAssertion( "down regulation of striated muscle cell differentiation") +AnnotationAssertion( "down-regulation of striated muscle cell differentiation") +AnnotationAssertion( "downregulation of striated muscle cell differentiation") +AnnotationAssertion( "inhibition of striated muscle cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051154") +AnnotationAssertion(rdfs:label "negative regulation of striated muscle cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of striated muscle cell differentiation) + +AnnotationAssertion(Annotation( "CL:0000737") Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of striated muscle cell differentiation.") +AnnotationAssertion( "up regulation of striated muscle cell differentiation") +AnnotationAssertion( "up-regulation of striated muscle cell differentiation") +AnnotationAssertion( "upregulation of striated muscle cell differentiation") +AnnotationAssertion( "activation of striated muscle cell differentiation") +AnnotationAssertion( "stimulation of striated muscle cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051155") +AnnotationAssertion(rdfs:label "positive regulation of striated muscle cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (nuclear export) + +AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of substances out of the nucleus.") +AnnotationAssertion( "export from nucleus") +AnnotationAssertion( "nucleus export") +AnnotationAssertion( "substance nuclear export") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051168") +AnnotationAssertion(rdfs:label "nuclear export") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (nuclear transport) + +AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of substances into, out of, or within the nucleus.") +AnnotationAssertion( "Wikipedia:Nuclear_transport") +AnnotationAssertion( "nucleus transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051169") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "nuclear transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (import into nucleus) + +AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of substances into the nucleus.") +AnnotationAssertion( "jl") +AnnotationAssertion( "2013-12-19T15:26:34Z") +AnnotationAssertion( "GO:1902593") +AnnotationAssertion( "nuclear import") +AnnotationAssertion( "nuclear translocation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051170") +AnnotationAssertion(rdfs:label "import into nucleus") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (regulation of nitrogen compound metabolic process) + +AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:tb") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds.") +AnnotationAssertion(Annotation( "GOC:tb") "regulation of nitrogen metabolic process") +AnnotationAssertion( "regulation of nitrogen metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051171") +AnnotationAssertion(rdfs:label "regulation of nitrogen compound metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (negative regulation of nitrogen compound metabolic process) + +AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:tb") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds.") +AnnotationAssertion( "down regulation of nitrogen metabolic process") +AnnotationAssertion( "down-regulation of nitrogen metabolic process") +AnnotationAssertion( "downregulation of nitrogen metabolic process") +AnnotationAssertion(Annotation( "GOC:tb") "negative regulation of nitrogen metabolic process") +AnnotationAssertion( "negative regulation of nitrogen metabolism") +AnnotationAssertion( "inhibition of nitrogen metabolic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051172") +AnnotationAssertion(rdfs:label "negative regulation of nitrogen compound metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of nitrogen compound metabolic process) + +AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:tb") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds.") +AnnotationAssertion(Annotation( "GOC:tb") "positive regulation of nitrogen metabolic process") +AnnotationAssertion( "positive regulation of nitrogen metabolism") +AnnotationAssertion( "up regulation of nitrogen metabolic process") +AnnotationAssertion( "up-regulation of nitrogen metabolic process") +AnnotationAssertion( "upregulation of nitrogen metabolic process") +AnnotationAssertion( "activation of nitrogen metabolic process") +AnnotationAssertion( "stimulation of nitrogen metabolic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051173") +AnnotationAssertion(rdfs:label "positive regulation of nitrogen compound metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of phosphorus metabolic process) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus.") +AnnotationAssertion( "regulation of phosphorus metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051174") +AnnotationAssertion(rdfs:label "regulation of phosphorus metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of sulfur metabolic process) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving sulfur or compounds containing sulfur.") +AnnotationAssertion( "down regulation of sulfur metabolic process") +AnnotationAssertion( "down-regulation of sulfur metabolic process") +AnnotationAssertion( "downregulation of sulfur metabolic process") +AnnotationAssertion( "negative regulation of sulfur metabolism") +AnnotationAssertion( "negative regulation of sulphur metabolic process") +AnnotationAssertion( "negative regulation of sulphur metabolism") +AnnotationAssertion( "inhibition of sulfur metabolic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051175") +AnnotationAssertion(rdfs:label "negative regulation of sulfur metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of sulfur metabolic process) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving sulfur or compounds containing sulfur.") +AnnotationAssertion( "positive regulation of sulfur metabolism") +AnnotationAssertion( "positive regulation of sulphur metabolic process") +AnnotationAssertion( "positive regulation of sulphur metabolism") +AnnotationAssertion( "up regulation of sulfur metabolic process") +AnnotationAssertion( "up-regulation of sulfur metabolic process") +AnnotationAssertion( "upregulation of sulfur metabolic process") +AnnotationAssertion( "activation of sulfur metabolic process") +AnnotationAssertion( "stimulation of sulfur metabolic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051176") +AnnotationAssertion(rdfs:label "positive regulation of sulfur metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (localization) AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:dos") "Any process in which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported, tethered to or otherwise maintained in a specific location. In the case of substances, localization may also be achieved via selective degradation.") @@ -39634,6 +93459,45 @@ AnnotationAssertion( "localization") SubClassOf( ) +# Class: (sequestering of calcium ion) + +AnnotationAssertion(Annotation( "GOC:ai") "The process of binding or confining calcium ions such that they are separated from other components of a biological system.") +AnnotationAssertion( "calcium ion (Ca2+) retention") +AnnotationAssertion( "calcium ion (Ca2+) sequestering") +AnnotationAssertion( "calcium ion (Ca2+) sequestration") +AnnotationAssertion( "calcium ion (Ca2+) storage") +AnnotationAssertion( "retention of calcium ion (Ca2+)") +AnnotationAssertion( "sequestering of calcium ion (Ca2+)") +AnnotationAssertion( "sequestration of calcium ion (Ca2+)") +AnnotationAssertion( "storage of calcium ion (Ca2+)") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "calcium ion storage activity") +AnnotationAssertion( "negative regulation of calcium ion (Ca2+) transport") +AnnotationAssertion( "GO:0051208") +AnnotationAssertion(rdfs:label "sequestering of calcium ion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (release of sequestered calcium ion into cytosol) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:hjd") Annotation( "GOC:mtg_lung") Annotation( "PMID:1814929") "The process in which calcium ions sequestered in the endoplasmic reticulum, Golgi apparatus or mitochondria are released into the cytosolic compartment.") +AnnotationAssertion( "calcium ion (Ca2+) mobilization") +AnnotationAssertion( "calcium mobilization") +AnnotationAssertion( "cytoplasmic release of sequestered calcium ion (Ca2+)") +AnnotationAssertion( "cytoplasmic release of stored calcium ion (Ca2+)") +AnnotationAssertion( "release of sequestered calcium ion (Ca2+)") +AnnotationAssertion( "release of sequestered calcium ion into cytoplasm") +AnnotationAssertion( "release of stored calcium ion (Ca2+)") +AnnotationAssertion( "release of stored calcium ion (Ca2+) into cytoplasm") +AnnotationAssertion( "cytosolic release of sequestered calcium ion (Ca2+)") +AnnotationAssertion( "cytosolic release of stored calcium ion (Ca2+)") +AnnotationAssertion( "release of stored calcium ion (Ca2+) into cytosol") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051209") +AnnotationAssertion(rdfs:label "release of sequestered calcium ion into cytosol") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf( ) + # Class: (cartilage development) AnnotationAssertion(Annotation( "GOC:cjm") Annotation( "PMID:23251424") "The process whose specific outcome is the progression of a cartilage element over time, from its formation to the mature structure. Cartilage elements are skeletal elements that consist of connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.") @@ -39647,10 +93511,52 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0051216") AnnotationAssertion(rdfs:label "cartilage development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (positive regulation of protein transport) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion( "up regulation of protein transport") +AnnotationAssertion( "up-regulation of protein transport") +AnnotationAssertion( "upregulation of protein transport") +AnnotationAssertion( "activation of protein transport") +AnnotationAssertion( "stimulation of protein transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051222") +AnnotationAssertion(rdfs:label "positive regulation of protein transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of protein transport) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051223") +AnnotationAssertion(rdfs:label "regulation of protein transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of protein transport) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion( "down regulation of protein transport") +AnnotationAssertion( "down-regulation of protein transport") +AnnotationAssertion( "downregulation of protein transport") +AnnotationAssertion( "inhibition of protein transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051224") +AnnotationAssertion(rdfs:label "negative regulation of protein transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + # Class: (establishment of localization) AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:dos") "Any process that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation.") @@ -39666,14 +93572,55 @@ AnnotationAssertion( "establishment of localization") SubClassOf( ) +# Class: (maintenance of location) + +AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process in which a cell, substance or cellular entity, such as a protein complex or organelle, is maintained in a location and prevented from moving elsewhere.") +AnnotationAssertion( "maintenance of localization") +AnnotationAssertion( "retention") +AnnotationAssertion( "sequestering") +AnnotationAssertion( "storage") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051235") +AnnotationAssertion(rdfs:label "maintenance of location") +SubClassOf( ) + +# Class: (establishment of RNA localization) + +AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of RNA to a specific location.") +AnnotationAssertion( "RNA positioning") +AnnotationAssertion( "RNA recruitment") +AnnotationAssertion(Annotation( "GOC:mah") "establishment of RNA localisation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051236") +AnnotationAssertion(rdfs:label "establishment of RNA localization") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (regulation of multicellular organismal process) AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs.") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0051239") AnnotationAssertion(rdfs:label "regulation of multicellular organismal process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (positive regulation of multicellular organismal process) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of an organismal process, any of the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs.") +AnnotationAssertion( "up regulation of multicellular organismal process") +AnnotationAssertion( "up-regulation of multicellular organismal process") +AnnotationAssertion( "upregulation of multicellular organismal process") +AnnotationAssertion( "activation of multicellular organismal process") +AnnotationAssertion( "stimulation of multicellular organismal process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051240") +AnnotationAssertion(rdfs:label "positive regulation of multicellular organismal process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (negative regulation of multicellular organismal process) AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of an organismal process, the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs.") @@ -39684,10 +93631,312 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0051241") AnnotationAssertion(rdfs:label "negative regulation of multicellular organismal process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (regulation of protein metabolic process) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a protein.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/23112"^^xsd:anyURI) +AnnotationAssertion( "GO:0032268") +AnnotationAssertion( "regulation of protein metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "regulation of cellular protein metabolic process") +AnnotationAssertion( "regulation of cellular protein metabolism") +AnnotationAssertion( "GO:0051246") +AnnotationAssertion(rdfs:label "regulation of protein metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of protein metabolic process) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/23112"^^xsd:anyURI) +AnnotationAssertion( "GO:0032270") +AnnotationAssertion( "positive regulation of cellular protein metabolic process") +AnnotationAssertion( "positive regulation of cellular protein metabolism") +AnnotationAssertion( "positive regulation of protein metabolism") +AnnotationAssertion( "up regulation of cellular protein metabolic process") +AnnotationAssertion( "up regulation of protein metabolic process") +AnnotationAssertion( "up-regulation of cellular protein metabolic process") +AnnotationAssertion( "up-regulation of protein metabolic process") +AnnotationAssertion( "upregulation of cellular protein metabolic process") +AnnotationAssertion( "upregulation of protein metabolic process") +AnnotationAssertion( "activation of cellular protein metabolic process") +AnnotationAssertion( "activation of protein metabolic process") +AnnotationAssertion( "stimulation of cellular protein metabolic process") +AnnotationAssertion( "stimulation of protein metabolic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051247") +AnnotationAssertion(rdfs:label "positive regulation of protein metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of protein metabolic process) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of chemical reactions and pathways involving a protein.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/23112"^^xsd:anyURI) +AnnotationAssertion( "GO:0032269") +AnnotationAssertion( "down regulation of cellular protein metabolic process") +AnnotationAssertion( "down regulation of protein metabolic process") +AnnotationAssertion( "down-regulation of cellular protein metabolic process") +AnnotationAssertion( "down-regulation of protein metabolic process") +AnnotationAssertion( "downregulation of cellular protein metabolic process") +AnnotationAssertion( "downregulation of protein metabolic process") +AnnotationAssertion( "negative regulation of cellular protein metabolic process") +AnnotationAssertion( "negative regulation of cellular protein metabolism") +AnnotationAssertion( "negative regulation of protein metabolism") +AnnotationAssertion( "inhibition of cellular protein metabolic process") +AnnotationAssertion( "inhibition of protein metabolic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051248") +AnnotationAssertion(rdfs:label "negative regulation of protein metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of lymphocyte activation) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of lymphocyte activation.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051249") +AnnotationAssertion(rdfs:label "regulation of lymphocyte activation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (negative regulation of lymphocyte activation) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte activation.") +AnnotationAssertion( "down regulation of lymphocyte activation") +AnnotationAssertion( "down-regulation of lymphocyte activation") +AnnotationAssertion( "downregulation of lymphocyte activation") +AnnotationAssertion( "inhibition of lymphocyte activation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051250") +AnnotationAssertion(rdfs:label "negative regulation of lymphocyte activation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of lymphocyte activation) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of lymphocyte activation.") +AnnotationAssertion( "up regulation of lymphocyte activation") +AnnotationAssertion( "up-regulation of lymphocyte activation") +AnnotationAssertion( "upregulation of lymphocyte activation") +AnnotationAssertion( "activation of lymphocyte activation") +AnnotationAssertion( "stimulation of lymphocyte activation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051251") +AnnotationAssertion(rdfs:label "positive regulation of lymphocyte activation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of RNA metabolic process) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving RNA.") +AnnotationAssertion( "regulation of RNA metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051252") +AnnotationAssertion(rdfs:label "regulation of RNA metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of RNA metabolic process) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving RNA.") +AnnotationAssertion( "down regulation of RNA metabolic process") +AnnotationAssertion( "down-regulation of RNA metabolic process") +AnnotationAssertion( "downregulation of RNA metabolic process") +AnnotationAssertion( "negative regulation of RNA metabolism") +AnnotationAssertion( "inhibition of RNA metabolic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051253") +AnnotationAssertion(rdfs:label "negative regulation of RNA metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of RNA metabolic process) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving RNA.") +AnnotationAssertion( "positive regulation of RNA metabolism") +AnnotationAssertion( "up regulation of RNA metabolic process") +AnnotationAssertion( "up-regulation of RNA metabolic process") +AnnotationAssertion( "upregulation of RNA metabolic process") +AnnotationAssertion( "activation of RNA metabolic process") +AnnotationAssertion( "stimulation of RNA metabolic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051254") +AnnotationAssertion(rdfs:label "positive regulation of RNA metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (protein polymerization) + +AnnotationAssertion(Annotation( "GOC:ai") "The process of creating protein polymers, compounds composed of a large number of component monomers; polymeric proteins may be made up of different or identical monomers. Polymerization occurs by the addition of extra monomers to an existing poly- or oligomeric protein.") +AnnotationAssertion( "protein polymer biosynthesis") +AnnotationAssertion( "protein polymer biosynthetic process") +AnnotationAssertion( "protein polymer formation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051258") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "protein polymerization") +SubClassOf( ) + +# Class: (protein depolymerization) + +AnnotationAssertion(Annotation( "GOC:ai") "The process in which protein polymers, compounds composed of a large number of component monomers, are broken down. Depolymerization occurs by the successive removal of monomers from an existing poly- or oligomeric protein.") +AnnotationAssertion( "protein polymer breakdown") +AnnotationAssertion( "protein polymer catabolic process") +AnnotationAssertion( "protein polymer catabolism") +AnnotationAssertion( "protein polymer degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051261") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "protein depolymerization") +SubClassOf( ) + +# Class: (chromosome organization) + +AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:dph") Annotation( "GOC:jl") Annotation( "GOC:mah") "A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of chromosomes, structures composed of a very long molecule of DNA and associated proteins that carries hereditary information. This term covers covalent modifications at the molecular level as well as spatial relationships among the major components of a chromosome.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/22811"^^xsd:anyURI) +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/4585"^^xsd:anyURI) +AnnotationAssertion( "GO:0006323") +AnnotationAssertion( "GO:0007001") +AnnotationAssertion( "GO:0051277") +AnnotationAssertion( "DNA condensation") +AnnotationAssertion( "chromosome organisation") +AnnotationAssertion( "DNA packaging") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:mah") "chromosome organization and biogenesis") +AnnotationAssertion( "maintenance of genome integrity") +AnnotationAssertion( "nuclear genome maintenance") +AnnotationAssertion( "GO:0051276") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "chromosome organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of release of sequestered calcium ion into cytosol) + +AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:tb") "Any process that modulates the frequency, rate or extent of the release into the cytosolic compartment of calcium ions sequestered in the endoplasmic reticulum or mitochondria.") +AnnotationAssertion( "regulation of release of sequestered calcium ion (Ca2+)") +AnnotationAssertion( "regulation of release of stored calcium ion (Ca2+)") +AnnotationAssertion( "regulation of calcium ion (Ca2+) mobilization") +AnnotationAssertion( "regulation of calcium mobilization") +AnnotationAssertion( "regulation of cytoplasmic release of sequestered calcium ion (Ca2+)") +AnnotationAssertion( "regulation of cytoplasmic release of stored calcium ion (Ca2+)") +AnnotationAssertion( "regulation of release of stored calcium ion (Ca2+) into cytoplasm") +AnnotationAssertion( "regulation of release of stored calcium ion (Ca2+) into cytosol") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051279") +AnnotationAssertion(rdfs:label "regulation of release of sequestered calcium ion into cytosol") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of release of sequestered calcium ion into cytosol) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of the release into the cytosolic compartment of calcium ions sequestered in the endoplasmic reticulum or mitochondria.") +AnnotationAssertion( "negative regulation of calcium ion (Ca2+) mobilization") +AnnotationAssertion( "negative regulation of calcium mobilization") +AnnotationAssertion( "negative regulation of cytoplasmic release of sequestered calcium ion (Ca2+)") +AnnotationAssertion( "negative regulation of cytoplasmic release of stored calcium ion (Ca2+)") +AnnotationAssertion( "negative regulation of release of sequestered calcium ion (Ca2+)") +AnnotationAssertion( "negative regulation of release of sequestered calcium ion into cytoplasm") +AnnotationAssertion( "negative regulation of release of stored calcium ion (Ca2+)") +AnnotationAssertion( "negative regulation of release of stored calcium ion (Ca2+) into cytoplasm") +AnnotationAssertion( "down regulation of release of sequestered calcium ion into cytosol") +AnnotationAssertion( "down-regulation of release of sequestered calcium ion into cytosol") +AnnotationAssertion( "downregulation of release of sequestered calcium ion into cytosol") +AnnotationAssertion( "negative regulation of cytosolic release of sequestered calcium ion (Ca2+)") +AnnotationAssertion( "negative regulation of cytosolic release of stored calcium ion (Ca2+)") +AnnotationAssertion( "negative regulation of release of stored calcium ion (Ca2+) into cytosol") +AnnotationAssertion( "inhibition of release of sequestered calcium ion into cytosol") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051280") +AnnotationAssertion(rdfs:label "negative regulation of release of sequestered calcium ion into cytosol") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of release of sequestered calcium ion into cytosol) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of the release into the cytosolic compartment of calcium ions sequestered in the endoplasmic reticulum or mitochondria.") +AnnotationAssertion( "positive regulation of calcium ion (Ca2+) mobilization") +AnnotationAssertion( "positive regulation of calcium mobilization") +AnnotationAssertion( "positive regulation of cytoplasmic release of sequestered calcium ion (Ca2+)") +AnnotationAssertion( "positive regulation of cytoplasmic release of stored calcium ion (Ca2+)") +AnnotationAssertion( "positive regulation of release of sequestered calcium ion (Ca2+)") +AnnotationAssertion( "positive regulation of release of sequestered calcium ion into cytoplasm") +AnnotationAssertion( "positive regulation of release of stored calcium ion (Ca2+)") +AnnotationAssertion( "positive regulation of release of stored calcium ion (Ca2+) into cytoplasm") +AnnotationAssertion( "positive regulation of cytosolic release of sequestered calcium ion (Ca2+)") +AnnotationAssertion( "positive regulation of cytosolic release of stored calcium ion (Ca2+)") +AnnotationAssertion( "positive regulation of release of stored calcium ion (Ca2+) into cytosol") +AnnotationAssertion( "up regulation of release of sequestered calcium ion into cytosol") +AnnotationAssertion( "up-regulation of release of sequestered calcium ion into cytosol") +AnnotationAssertion( "upregulation of release of sequestered calcium ion into cytosol") +AnnotationAssertion( "activation of release of sequestered calcium ion into cytosol") +AnnotationAssertion( "stimulation of release of sequestered calcium ion into cytosol") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051281") +AnnotationAssertion(rdfs:label "positive regulation of release of sequestered calcium ion into cytosol") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of sequestering of calcium ion) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of the binding or confining calcium ions such that they are separated from other components of a biological system.") +AnnotationAssertion( "regulation of calcium ion (Ca2+) retention") +AnnotationAssertion( "regulation of calcium ion (Ca2+) sequestering") +AnnotationAssertion( "regulation of calcium ion (Ca2+) sequestration") +AnnotationAssertion( "regulation of calcium ion (Ca2+) storage") +AnnotationAssertion( "regulation of retention of calcium ion (Ca2+)") +AnnotationAssertion( "regulation of sequestering of calcium ion (Ca2+)") +AnnotationAssertion( "regulation of sequestration of calcium ion (Ca2+)") +AnnotationAssertion( "regulation of storage of calcium ion (Ca2+)") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051282") +AnnotationAssertion(rdfs:label "regulation of sequestering of calcium ion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (negative regulation of sequestering of calcium ion) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of the binding or confining calcium ions such that they are separated from other components of a biological system.") +AnnotationAssertion( "down regulation of sequestering of calcium ion") +AnnotationAssertion( "down-regulation of sequestering of calcium ion") +AnnotationAssertion( "downregulation of sequestering of calcium ion") +AnnotationAssertion( "negative regulation of calcium ion (Ca2+) retention") +AnnotationAssertion( "negative regulation of calcium ion (Ca2+) sequestering") +AnnotationAssertion( "negative regulation of calcium ion (Ca2+) sequestration") +AnnotationAssertion( "negative regulation of calcium ion (Ca2+) storage") +AnnotationAssertion( "negative regulation of retention of calcium ion (Ca2+)") +AnnotationAssertion( "negative regulation of sequestering of calcium ion (Ca2+)") +AnnotationAssertion( "negative regulation of sequestration of calcium ion (Ca2+)") +AnnotationAssertion( "negative regulation of storage of calcium ion (Ca2+)") +AnnotationAssertion( "inhibition of sequestering of calcium ion") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051283") +AnnotationAssertion(rdfs:label "negative regulation of sequestering of calcium ion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (positive regulation of sequestering of calcium ion) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of the binding or confining calcium ions such that they are separated from other components of a biological system.") +AnnotationAssertion( "positive regulation of calcium ion (Ca2+) retention") +AnnotationAssertion( "positive regulation of calcium ion (Ca2+) sequestering") +AnnotationAssertion( "positive regulation of calcium ion (Ca2+) sequestration") +AnnotationAssertion( "positive regulation of calcium ion (Ca2+) storage") +AnnotationAssertion( "positive regulation of retention of calcium ion (Ca2+)") +AnnotationAssertion( "positive regulation of sequestering of calcium ion (Ca2+)") +AnnotationAssertion( "positive regulation of sequestration of calcium ion (Ca2+)") +AnnotationAssertion( "positive regulation of storage of calcium ion (Ca2+)") +AnnotationAssertion( "up regulation of sequestering of calcium ion") +AnnotationAssertion( "up-regulation of sequestering of calcium ion") +AnnotationAssertion( "upregulation of sequestering of calcium ion") +AnnotationAssertion( "activation of sequestering of calcium ion") +AnnotationAssertion( "stimulation of sequestering of calcium ion") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051284") +AnnotationAssertion(rdfs:label "positive regulation of sequestering of calcium ion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + # Class: (cell division) AnnotationAssertion(Annotation( "GOC:di") Annotation( "GOC:go_curators") Annotation( "GOC:pr") "The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells.") @@ -39701,6 +93950,586 @@ AnnotationAssertion(rdfs:comment "No AnnotationAssertion(rdfs:label "cell division") SubClassOf( ) +# Class: (regulation of cell division) + +AnnotationAssertion(Annotation( "GOC:go_curators") "Any process that modulates the frequency, rate or extent of the physical partitioning and separation of a cell into daughter cells.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051302") +AnnotationAssertion(rdfs:label "regulation of cell division") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (establishment of chromosome localization) + +AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of a chromosome to a specific location.") +AnnotationAssertion( "chromosome positioning") +AnnotationAssertion(Annotation( "GOC:mah") "establishment of chromosome localisation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051303") +AnnotationAssertion(rdfs:label "establishment of chromosome localization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (meiotic cell cycle) + +AnnotationAssertion(Annotation( "GOC:ai") "Progression through the phases of the meiotic cell cycle, in which canonically a cell replicates to produce four offspring with half the chromosomal content of the progenitor cell via two nuclear divisions.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/24599"^^xsd:anyURI) +AnnotationAssertion( "GO:0007126") +AnnotationAssertion( "Wikipedia:Meiosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "meiosis") +AnnotationAssertion( "GO:0051321") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:comment "Note that this term should not be confused with 'GO:0140013 ; meiotic nuclear division'. 'GO:0051321 ; meiotic cell cycle represents the entire mitotic cell cycle, while 'GO:0140013 meiotic nuclear division' specifically represents the actual nuclear division step of the mitotic cell cycle.") +AnnotationAssertion(rdfs:label "meiotic cell cycle") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectAllValuesFrom( )) + +# Class: (regulation of hydrolase activity) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3.") +AnnotationAssertion( "hydrolase regulator") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051336") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "regulation of hydrolase activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of transferase activity) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2.") +AnnotationAssertion( "transferase regulator") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051338") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:comment "This term is useful for grouping, but is too general for manual annotation. Please use a child term instead.") +AnnotationAssertion(rdfs:label "regulation of transferase activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of hydrolase activity) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds.") +AnnotationAssertion( "hydrolase activator") +AnnotationAssertion( "up regulation of hydrolase activity") +AnnotationAssertion( "up-regulation of hydrolase activity") +AnnotationAssertion( "upregulation of hydrolase activity") +AnnotationAssertion( "activation of hydrolase activity") +AnnotationAssertion( "stimulation of hydrolase activity") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051345") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "positive regulation of hydrolase activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of hydrolase activity) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops or reduces the rate of hydrolase activity, the catalysis of the hydrolysis of various bonds.") +AnnotationAssertion( "down regulation of hydrolase activity") +AnnotationAssertion( "down-regulation of hydrolase activity") +AnnotationAssertion( "downregulation of hydrolase activity") +AnnotationAssertion( "hydrolase inhibitor") +AnnotationAssertion( "inhibition of hydrolase activity") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051346") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "negative regulation of hydrolase activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of transferase activity) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor.") +AnnotationAssertion( "transferase activator") +AnnotationAssertion( "up regulation of transferase activity") +AnnotationAssertion( "up-regulation of transferase activity") +AnnotationAssertion( "upregulation of transferase activity") +AnnotationAssertion( "activation of transferase activity") +AnnotationAssertion( "stimulation of transferase activity") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051347") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:comment "This term is useful for grouping, but is too general for manual annotation. Please use a child term instead.") +AnnotationAssertion(rdfs:label "positive regulation of transferase activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of transferase activity) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops or reduces the rate of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor.") +AnnotationAssertion( "down regulation of transferase activity") +AnnotationAssertion( "down-regulation of transferase activity") +AnnotationAssertion( "downregulation of transferase activity") +AnnotationAssertion( "transferase inhibitor") +AnnotationAssertion( "inhibition of transferase activity") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051348") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:comment "This term is useful for grouping, but is too general for manual annotation. Please use a child term instead.") +AnnotationAssertion(rdfs:label "negative regulation of transferase activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (proprioception involved in equilibrioception) + +AnnotationAssertion(Annotation( "GOC:ai") "The series of events contributing to equilibrioception by which an organism senses the position, location, orientation, and movement of the body and its parts. Proprioception plays an important role in the ability of an organism to perceive its orientation with respect to gravity.") +AnnotationAssertion( "equilibrioception by proprioception") +AnnotationAssertion( "perception of orientation with respect to gravity by proprioception") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "proprioception during equilibrioception") +AnnotationAssertion( "GO:0051355") +AnnotationAssertion(rdfs:label "proprioception involved in equilibrioception") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (visual perception involved in equilibrioception) + +AnnotationAssertion(Annotation( "GOC:ai") "The series of events during equilibrioception required for an organism to receive a visual stimulus, convert it to a molecular signal, and recognize and characterize the signal. Visual input plays an important role in the ability of an organism to perceive its orientation with respect to gravity.") +AnnotationAssertion( "perception of orientation with respect to gravity by visual perception") +AnnotationAssertion( "equilibrioception by visual perception") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "visual perception during equilibrioception") +AnnotationAssertion( "GO:0051356") +AnnotationAssertion(rdfs:label "visual perception involved in equilibrioception") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (serotonin binding) + +AnnotationAssertion(Annotation( "GOC:ai") "Binding to serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties.") +AnnotationAssertion( "5-hydroxytryptamine binding") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0051378") +AnnotationAssertion(rdfs:label "serotonin binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (epinephrine binding) + +AnnotationAssertion(Annotation( "GOC:ai") "Binding to epinephrine, a hormone produced by the medulla of the adrenal glands that increases heart activity, improves the power and prolongs the action of muscles, and increases the rate and depth of breathing. It is synthesized by the methylation of norepinephrine.") +AnnotationAssertion( "adrenaline binding") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0051379") +AnnotationAssertion(rdfs:label "epinephrine binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (norepinephrine binding) + +AnnotationAssertion(Annotation( "GOC:ai") "Binding to norepinephrine, (3,4-dihydroxyphenyl-2-aminoethanol), a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine.") +AnnotationAssertion( "noradrenaline binding") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0051380") +AnnotationAssertion(rdfs:label "norepinephrine binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (histamine binding) + +AnnotationAssertion(Annotation( "GOC:ai") "Binding to histamine, a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans.") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0051381") +AnnotationAssertion(rdfs:label "histamine binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (response to glucocorticoid) + +AnnotationAssertion(Annotation( "GOC:ai") Annotation( "PMID:9884123") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucocorticoid stimulus. Glucocorticoids are hormonal C21 corticosteroids synthesized from cholesterol with the ability to bind with the cortisol receptor and trigger similar effects. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects.") +AnnotationAssertion(Annotation( "GOC:dos") "response to glucocorticoid stimulus") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051384") +AnnotationAssertion(rdfs:label "response to glucocorticoid") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (response to mineralocorticoid) + +AnnotationAssertion(Annotation( "GOC:ai") Annotation( "PMID:9884123") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mineralocorticoid stimulus. Mineralocorticoids are hormonal C21 corticosteroids synthesized from cholesterol and characterized by their similarity to aldosterone. Mineralocorticoids act primarily on water and electrolyte balance.") +AnnotationAssertion(Annotation( "GOC:dos") "response to mineralocorticoid stimulus") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051385") +AnnotationAssertion(rdfs:label "response to mineralocorticoid") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (neuron apoptotic process) + +AnnotationAssertion(Annotation( "CL:0000540") Annotation( "GOC:mtg_apoptosis") "Any apoptotic process in a neuron, the basic cellular unit of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system.") +AnnotationAssertion( "apoptosis of neuronal cells") +AnnotationAssertion( "apoptosis of neurons") +AnnotationAssertion( "neuron programmed cell death by apoptosis") +AnnotationAssertion( "neuronal cell apoptosis") +AnnotationAssertion( "neuronal cell programmed cell death by apoptosis") +AnnotationAssertion( "programmed cell death of neuronal cells by apoptosis") +AnnotationAssertion( "programmed cell death of neurons by apoptosis") +AnnotationAssertion( "programmed cell death, neuronal cells") +AnnotationAssertion( "programmed cell death, neurons") +AnnotationAssertion( "neuron apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051402") +AnnotationAssertion(rdfs:label "neuron apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (detoxification of nitrogen compound) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that reduces or removes the toxicity of nitrogenous compounds which are dangerous or toxic. This includes the aerobic conversion of toxic compounds to harmless substances.") +AnnotationAssertion( "detoxification of nitrogenous compound") +AnnotationAssertion( "nitric oxide (NO) detoxification") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051410") +AnnotationAssertion(rdfs:label "detoxification of nitrogen compound") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (regulation of meiotic cell cycle) + +AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the rate or extent of progression through the meiotic cell cycle.") +AnnotationAssertion( "meiotic cell cycle modulation") +AnnotationAssertion( "meiotic cell cycle regulation") +AnnotationAssertion( "modulation of meiotic cell cycle progression") +AnnotationAssertion( "regulation of meiotic cell cycle progression") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "regulation of progression through meiotic cell cycle") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "meiotic cell cycle regulator") +AnnotationAssertion( "GO:0051445") +AnnotationAssertion(rdfs:label "regulation of meiotic cell cycle") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of meiotic cell cycle) + +AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that activates or increases the frequency, rate or extent of progression through the meiotic cell cycle.") +AnnotationAssertion( "positive regulation of meiotic cell cycle progression") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "positive regulation of progression through meiotic cell cycle") +AnnotationAssertion( "up regulation of progression through meiotic cell cycle") +AnnotationAssertion( "up-regulation of progression through meiotic cell cycle") +AnnotationAssertion( "upregulation of progression through meiotic cell cycle") +AnnotationAssertion( "activation of progression through meiotic cell cycle") +AnnotationAssertion( "stimulation of progression through meiotic cell cycle") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051446") +AnnotationAssertion(rdfs:label "positive regulation of meiotic cell cycle") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of meiotic cell cycle) + +AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that stops, prevents or reduces the rate or extent of progression through the meiotic cell cycle.") +AnnotationAssertion( "down regulation of progression through meiotic cell cycle") +AnnotationAssertion( "down-regulation of progression through meiotic cell cycle") +AnnotationAssertion( "downregulation of progression through meiotic cell cycle") +AnnotationAssertion( "negative regulation of meiotic cell cycle progression") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "negative regulation of progression through meiotic cell cycle") +AnnotationAssertion( "inhibition of progression through meiotic cell cycle") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051447") +AnnotationAssertion(rdfs:label "negative regulation of meiotic cell cycle") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (myoblast proliferation) + +AnnotationAssertion(Annotation( "CL:0000056") Annotation( "GOC:ai") Annotation( "GOC:mtg_muscle") "The multiplication or reproduction of myoblasts, resulting in the expansion of a myoblast cell population. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051450") +AnnotationAssertion(rdfs:label "myoblast proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (myoblast migration) + +AnnotationAssertion(Annotation( "CL:0000056") Annotation( "GOC:ai") Annotation( "GOC:mtg_muscle") "The orderly movement of a myoblast from one site to another, often during the development of a multicellular organism. A myoblast is a cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051451") +AnnotationAssertion(rdfs:label "myoblast migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (maintenance of protein location in nucleus) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process in which a protein is maintained in the nucleus and prevented from moving elsewhere. These include sequestration within the nucleus, protein stabilization to prevent transport elsewhere and the active retrieval of proteins that escape the nucleus.") +AnnotationAssertion( "maintenance of nuclear protein localization") +AnnotationAssertion( "maintenance of protein location in cell nucleus") +AnnotationAssertion( "nuclear protein retention") +AnnotationAssertion( "nuclear protein sequestering") +AnnotationAssertion( "nuclear protein sequestration") +AnnotationAssertion( "protein retention in nucleus") +AnnotationAssertion( "protein sequestration in nucleus") +AnnotationAssertion( "protein storage in nucleus") +AnnotationAssertion( "protein-nuclear retention") +AnnotationAssertion( "sequestration of protein in nucleus") +AnnotationAssertion( "storage of protein in nucleus") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "maintenance of protein localization in nucleus") +AnnotationAssertion( "GO:0051457") +AnnotationAssertion(rdfs:label "maintenance of protein location in nucleus") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectAllValuesFrom( )) + +# Class: (corticotropin secretion) + +AnnotationAssertion(Annotation( "GOC:cjm") Annotation( "PMID:11027914") "The regulated release of corticotropin by a cell. Corticotropin hormone is a polypeptide hormone synthesized and secreted from corticotropes in the anterior lobe of the pituitary gland in response to corticotropin-releasing hormone (CRH) released by the hypothalamus.") +AnnotationAssertion( "ACTH secretion") +AnnotationAssertion( "adrenocorticotropic hormone secretion") +AnnotationAssertion( "adrenotropic hormone secretion") +AnnotationAssertion( "adrenotropin secretion") +AnnotationAssertion( "corticotropic hormone secretion") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "adrenocorticotropin secretion") +AnnotationAssertion( "GO:0051458") +AnnotationAssertion(rdfs:label "corticotropin secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of corticotropin secretion) + +AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:dph") "Any process that modulates the frequency, rate or extent of the regulated release of corticotropic hormone from a cell.") +AnnotationAssertion( "regulation of ACTH secretion") +AnnotationAssertion(Annotation( "GOC:dph") "regulation of adrenocorticotropic hormone secretion") +AnnotationAssertion( "regulation of adrenocorticotropin secretion") +AnnotationAssertion( "regulation of adrenotropin hormone secretion") +AnnotationAssertion( "regulation of adrenotropin secretion") +AnnotationAssertion( "regulation of corticotropic hormone secretion") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051459") +AnnotationAssertion(rdfs:label "regulation of corticotropin secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (negative regulation of corticotropin secretion) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of corticotropic hormone from a cell.") +AnnotationAssertion( "down regulation of adrenocorticotropin secretion") +AnnotationAssertion( "down-regulation of adrenocorticotropin secretion") +AnnotationAssertion( "downregulation of adrenocorticotropin secretion") +AnnotationAssertion( "negative regulation of ACTH secretion") +AnnotationAssertion( "negative regulation of adrenocorticotropic hormone secretion") +AnnotationAssertion( "negative regulation of adrenocorticotropin secretion") +AnnotationAssertion( "negative regulation of adrenotropic hormone secretion") +AnnotationAssertion( "negative regulation of adrenotropin secretion") +AnnotationAssertion( "negative regulation of corticotropic hormone secretion") +AnnotationAssertion( "inhibition of adrenocorticotropin secretion") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051460") +AnnotationAssertion(rdfs:label "negative regulation of corticotropin secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (positive regulation of corticotropin secretion) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of the regulated release of corticotropin hormone from a cell.") +AnnotationAssertion( "positive regulation of ACTH secretion") +AnnotationAssertion( "positive regulation of adrenocorticotropic hormone secretion") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "positive regulation of adrenocorticotropin secretion") +AnnotationAssertion( "positive regulation of adrenotropic hormone secretion") +AnnotationAssertion( "positive regulation of adrenotropin secretion") +AnnotationAssertion( "positive regulation of corticotropic hormone secretion") +AnnotationAssertion( "up regulation of adrenocorticotropin secretion") +AnnotationAssertion( "up-regulation of adrenocorticotropin secretion") +AnnotationAssertion( "upregulation of adrenocorticotropin secretion") +AnnotationAssertion( "activation of adrenocorticotropin secretion") +AnnotationAssertion( "stimulation of adrenocorticotropin secretion") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051461") +AnnotationAssertion(rdfs:label "positive regulation of corticotropin secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (vesicle fusion with vacuole) + +AnnotationAssertion(Annotation( "GOC:ai") "The joining of the lipid bilayer membrane around a vesicle with the lipid bilayer membrane around the vacuole.") +AnnotationAssertion( "GO:0042146") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "heterotypic vacuole fusion (non-autophagic)") +AnnotationAssertion( "heterotypic vacuole fusion, non-autophagic") +AnnotationAssertion( "GO:0051469") +AnnotationAssertion(rdfs:label "vesicle fusion with vacuole") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of cytoskeleton organization) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures.") +AnnotationAssertion(Annotation( "GOC:mah") "regulation of cytoskeleton organisation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:mah") "regulation of cytoskeleton organization and biogenesis") +AnnotationAssertion( "GO:0051493") +AnnotationAssertion(rdfs:label "regulation of cytoskeleton organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of cytoskeleton organization) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures.") +AnnotationAssertion( "down regulation of cytoskeleton organization") +AnnotationAssertion( "down-regulation of cytoskeleton organization") +AnnotationAssertion( "downregulation of cytoskeleton organization") +AnnotationAssertion(Annotation( "GOC:mah") "negative regulation of cytoskeleton organisation") +AnnotationAssertion( "inhibition of cytoskeleton organization") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:mah") "negative regulation of cytoskeleton organization and biogenesis") +AnnotationAssertion( "GO:0051494") +AnnotationAssertion(rdfs:label "negative regulation of cytoskeleton organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of cytoskeleton organization) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures.") +AnnotationAssertion(Annotation( "GOC:mah") "positive regulation of cytoskeleton organisation") +AnnotationAssertion( "up regulation of cytoskeleton organization") +AnnotationAssertion( "up-regulation of cytoskeleton organization") +AnnotationAssertion( "upregulation of cytoskeleton organization") +AnnotationAssertion( "activation of cytoskeleton organization") +AnnotationAssertion( "stimulation of cytoskeleton organization") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:mah") "positive regulation of cytoskeleton organization and biogenesis") +AnnotationAssertion( "GO:0051495") +AnnotationAssertion(rdfs:label "positive regulation of cytoskeleton organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (adenine nucleotide transport) + +AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of adenine nucleotides, ATP, ADP, and/or AMP, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051503") +AnnotationAssertion(rdfs:label "adenine nucleotide transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (keratinocyte migration) + +AnnotationAssertion(Annotation( "ISBN:0721662544") "The directed movement of a keratinocyte, epidermal cells which synthesize keratin, from one site to another.") +AnnotationAssertion( ) +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051546") +AnnotationAssertion(rdfs:label "keratinocyte migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses( ObjectSomeValuesFrom( )) + +# Class: (regulation of keratinocyte migration) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of keratinocyte migration.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051547") +AnnotationAssertion(rdfs:label "regulation of keratinocyte migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of keratinocyte migration) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of keratinocyte migration.") +AnnotationAssertion( "down regulation of keratinocyte migration") +AnnotationAssertion( "down-regulation of keratinocyte migration") +AnnotationAssertion( "downregulation of keratinocyte migration") +AnnotationAssertion( "inhibition of keratinocyte migration") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051548") +AnnotationAssertion(rdfs:label "negative regulation of keratinocyte migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of keratinocyte migration) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of keratinocyte migration.") +AnnotationAssertion( "up regulation of keratinocyte migration") +AnnotationAssertion( "up-regulation of keratinocyte migration") +AnnotationAssertion( "upregulation of keratinocyte migration") +AnnotationAssertion( "activation of keratinocyte migration") +AnnotationAssertion( "stimulation of keratinocyte migration") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051549") +AnnotationAssertion(rdfs:label "positive regulation of keratinocyte migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of neurotransmitter uptake) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of the directed movement of a neurotransmitter into a neuron or glial cell.") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "regulation of neurotransmitter import") +AnnotationAssertion( "regulation of neurotransmitter reuptake") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051580") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "regulation of neurotransmitter uptake") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of neurotransmitter uptake) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a neurotransmitter into a neuron or glial cell.") +AnnotationAssertion( "down regulation of neurotransmitter uptake") +AnnotationAssertion( "down-regulation of neurotransmitter uptake") +AnnotationAssertion( "downregulation of neurotransmitter uptake") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "negative regulation of neurotransmitter import") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051581") +AnnotationAssertion(rdfs:label "negative regulation of neurotransmitter uptake") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of neurotransmitter uptake) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of the directed movement of a neurotransmitter into a neuron or glial cell.") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "positive regulation of neurotransmitter import") +AnnotationAssertion( "up regulation of neurotransmitter uptake") +AnnotationAssertion( "up-regulation of neurotransmitter uptake") +AnnotationAssertion( "upregulation of neurotransmitter uptake") +AnnotationAssertion( "activation of neurotransmitter uptake") +AnnotationAssertion( "stimulation of neurotransmitter uptake") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051582") +AnnotationAssertion(rdfs:label "positive regulation of neurotransmitter uptake") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of neurotransmitter transport) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of the directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051588") +AnnotationAssertion(rdfs:label "regulation of neurotransmitter transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of neurotransmitter transport) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion( "down regulation of neurotransmitter transport") +AnnotationAssertion( "down-regulation of neurotransmitter transport") +AnnotationAssertion( "downregulation of neurotransmitter transport") +AnnotationAssertion( "inhibition of neurotransmitter transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051589") +AnnotationAssertion(rdfs:label "negative regulation of neurotransmitter transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of neurotransmitter transport) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of the directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion( "up regulation of neurotransmitter transport") +AnnotationAssertion( "up-regulation of neurotransmitter transport") +AnnotationAssertion( "upregulation of neurotransmitter transport") +AnnotationAssertion( "activation of neurotransmitter transport") +AnnotationAssertion( "stimulation of neurotransmitter transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051590") +AnnotationAssertion(rdfs:label "positive regulation of neurotransmitter transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (response to calcium ion) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus.") +AnnotationAssertion( "response to Ca2+ ion") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051592") +AnnotationAssertion(rdfs:label "response to calcium ion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (response to electrical stimulus) AnnotationAssertion(Annotation( "GOC:ai") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electrical stimulus.") @@ -39710,6 +94539,23 @@ AnnotationAssertion( "response to electrical stimulus") SubClassOf( ) +# Class: (proteolysis involved in protein catabolic process) + +AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:dph") Annotation( "GOC:tb") "The hydrolysis of a peptide bond or bonds within a protein as part of the chemical reactions and pathways resulting in the breakdown of a protein by individual cells.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/23112"^^xsd:anyURI) +AnnotationAssertion( "peptidolysis involved in cellular protein catabolic process") +AnnotationAssertion( "peptidolysis involved in cellular protein catabolism") +AnnotationAssertion( "proteolysis involved in cellular protein catabolic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "peptidolysis during cellular protein catabolic process") +AnnotationAssertion( "peptidolysis during cellular protein catabolism") +AnnotationAssertion( "proteolysis during cellular protein catabolic process") +AnnotationAssertion( "proteolysis during cellular protein catabolism") +AnnotationAssertion( "GO:0051603") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "proteolysis involved in protein catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (protein maturation) AnnotationAssertion(Annotation( "GOC:ai") "Any process leading to the attainment of the full functional capacity of a protein.") @@ -39738,6 +94584,225 @@ AnnotationAssertion( "detection of stimulus") SubClassOf( ) +# Class: (histamine transport) + +AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of histamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Histamine is a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051608") +AnnotationAssertion(rdfs:label "histamine transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (histamine uptake) + +AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of histamine into a cell, typically presynaptic neurons or glial cells. Histamine is a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans.") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "histamine import") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051615") +AnnotationAssertion(rdfs:label "histamine uptake") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of histamine uptake) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of the directed movement of the neurotransmitter histamine into a cell.") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "regulation of histamine import") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051616") +AnnotationAssertion(rdfs:label "regulation of histamine uptake") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of histamine uptake) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of histamine into a cell.") +AnnotationAssertion( "down regulation of histamine uptake") +AnnotationAssertion( "down-regulation of histamine uptake") +AnnotationAssertion( "downregulation of histamine uptake") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "negative regulation of histamine import") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051617") +AnnotationAssertion(rdfs:label "negative regulation of histamine uptake") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of histamine uptake) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of the directed movement of histamine into a cell.") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "positive regulation of histamine import") +AnnotationAssertion( "up regulation of histamine uptake") +AnnotationAssertion( "up-regulation of histamine uptake") +AnnotationAssertion( "upregulation of histamine uptake") +AnnotationAssertion( "activation of histamine uptake") +AnnotationAssertion( "stimulation of histamine uptake") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051618") +AnnotationAssertion(rdfs:label "positive regulation of histamine uptake") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (norepinephrine uptake) + +AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of norepinephrine into a cell, typically presynaptic neurons or glial cells. Norepinephrine (3,4-dihydroxyphenyl-2-aminoethanol) is a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine.") +AnnotationAssertion( "levarterenol reuptake") +AnnotationAssertion( "levarterenol uptake") +AnnotationAssertion( "noradrenaline reuptake") +AnnotationAssertion( "noradrenaline uptake") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "norepinephrine import") +AnnotationAssertion( "norepinephrine reuptake") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051620") +AnnotationAssertion(rdfs:label "norepinephrine uptake") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (regulation of norepinephrine uptake) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of the directed movement of the neurotransmitter norepinephrine into a cell.") +AnnotationAssertion( "regulation of levarterenol uptake") +AnnotationAssertion( "regulation of noradrenaline uptake") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "regulation of norepinephrine import") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051621") +AnnotationAssertion(rdfs:label "regulation of norepinephrine uptake") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of norepinephrine uptake) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of norepinephrine into a cell.") +AnnotationAssertion( "down regulation of norepinephrine uptake") +AnnotationAssertion( "down-regulation of norepinephrine uptake") +AnnotationAssertion( "downregulation of norepinephrine uptake") +AnnotationAssertion( "negative regulation of levarterenol uptake") +AnnotationAssertion( "negative regulation of noradrenaline uptake") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "negative regulation of norepinephrine import") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051622") +AnnotationAssertion(rdfs:label "negative regulation of norepinephrine uptake") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of norepinephrine uptake) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of the directed movement of norepinephrine into a cell.") +AnnotationAssertion( "positive regulation of levarterenol uptake") +AnnotationAssertion( "positive regulation of noradrenaline uptake") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "positive regulation of norepinephrine import") +AnnotationAssertion( "up regulation of norepinephrine uptake") +AnnotationAssertion( "up-regulation of norepinephrine uptake") +AnnotationAssertion( "upregulation of norepinephrine uptake") +AnnotationAssertion( "activation of norepinephrine uptake") +AnnotationAssertion( "stimulation of norepinephrine uptake") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051623") +AnnotationAssertion(rdfs:label "positive regulation of norepinephrine uptake") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (epinephrine uptake) + +AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of epinephrine into a cell, typically presynaptic neurons or glial cells. Epinephrine is a hormone produced by the medulla of the adrenal glands that increases heart activity, improves the power and prolongs the action of muscles, and increases the rate and depth of breathing. It is synthesized by the methylation of norepinephrine.") +AnnotationAssertion( "adrenaline reuptake") +AnnotationAssertion( "adrenaline uptake") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "epinephrine import") +AnnotationAssertion( "epinephrine reuptake") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051625") +AnnotationAssertion(rdfs:label "epinephrine uptake") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (regulation of epinephrine uptake) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of the directed movement of the neurotransmitter epinephrine into a cell.") +AnnotationAssertion( "regulation of adrenaline uptake") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "regulation of epinephrine import") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051626") +AnnotationAssertion(rdfs:label "regulation of epinephrine uptake") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of epinephrine uptake) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of epinephrine into a cell.") +AnnotationAssertion( "down regulation of epinephrine uptake") +AnnotationAssertion( "down-regulation of epinephrine uptake") +AnnotationAssertion( "downregulation of epinephrine uptake") +AnnotationAssertion( "negative regulation of adrenaline uptake") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "negative regulation of epinephrine import") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051627") +AnnotationAssertion(rdfs:label "negative regulation of epinephrine uptake") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of epinephrine uptake) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of the directed movement of epinephrine into a cell.") +AnnotationAssertion( "positive regulation of adrenaline uptake") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "positive regulation of epinephrine import") +AnnotationAssertion( "up regulation of epinephrine uptake") +AnnotationAssertion( "up-regulation of epinephrine uptake") +AnnotationAssertion( "upregulation of epinephrine uptake") +AnnotationAssertion( "activation of epinephrine uptake") +AnnotationAssertion( "stimulation of epinephrine uptake") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051628") +AnnotationAssertion(rdfs:label "positive regulation of epinephrine uptake") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (acetylcholine uptake) + +AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of acetylcholine into a cell, typically presynaptic neurons or glial cells. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues.") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "acetylcholine import") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051630") +AnnotationAssertion(rdfs:label "acetylcholine uptake") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (regulation of acetylcholine uptake) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of the directed movement of the neurotransmitter acetylcholine into a cell.") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "regulation of acetylcholine import") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051631") +AnnotationAssertion(rdfs:label "regulation of acetylcholine uptake") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (negative regulation of acetylcholine uptake) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of acetylcholine into a cell.") +AnnotationAssertion( "down regulation of acetylcholine uptake") +AnnotationAssertion( "down-regulation of acetylcholine uptake") +AnnotationAssertion( "downregulation of acetylcholine uptake") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "negative regulation of acetylcholine import") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051632") +AnnotationAssertion(rdfs:label "negative regulation of acetylcholine uptake") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (positive regulation of acetylcholine uptake) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of the directed movement of acetylcholine into a cell.") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "positive regulation of acetylcholine import") +AnnotationAssertion( "up regulation of acetylcholine uptake") +AnnotationAssertion( "up-regulation of acetylcholine uptake") +AnnotationAssertion( "upregulation of acetylcholine uptake") +AnnotationAssertion( "activation of acetylcholine uptake") +AnnotationAssertion( "stimulation of acetylcholine uptake") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051633") +AnnotationAssertion(rdfs:label "positive regulation of acetylcholine uptake") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (organelle localization) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process in which an organelle is transported to, and/or maintained in, a specific location.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/19809"^^xsd:anyURI) +AnnotationAssertion( "establishment and maintenance of organelle localization") +AnnotationAssertion(Annotation( "GOC:mah") "organelle localisation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051640") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "organelle localization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectAllValuesFrom( )) + # Class: (cellular localization) AnnotationAssertion(Annotation( "GOC:tb") Annotation( "GOC:vw") "A cellular localization process whereby a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a cell including the localization of substances or cellular entities to the cell membrane.") @@ -39758,6 +94823,195 @@ AnnotationAssertion(rdfs:label "cell SubClassOf( ) SubClassOf( ) +# Class: (Golgi localization) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process in which the Golgi is transported to, and/or maintained in, a specific location within the cell.") +AnnotationAssertion( "Golgi apparatus localization") +AnnotationAssertion( "Golgi body localization") +AnnotationAssertion(Annotation( "GOC:mah") "Golgi localisation") +AnnotationAssertion( "establishment and maintenance of Golgi localization") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051645") +AnnotationAssertion(rdfs:label "Golgi localization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (nucleus localization) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process in which the nucleus is transported to, and/or maintained in, a specific location within the cell.") +AnnotationAssertion( "cell nucleus localization") +AnnotationAssertion( "establishment and maintenance of nucleus localization") +AnnotationAssertion( "localization of nucleus") +AnnotationAssertion(Annotation( "GOC:mah") "nucleus localisation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051647") +AnnotationAssertion(rdfs:label "nucleus localization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (vesicle localization) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process in which a vesicle or vesicles are transported to, and/or maintained in, a specific location.") +AnnotationAssertion( "cytoplasmic vesicle localization") +AnnotationAssertion( "establishment and maintenance of vesicle localization") +AnnotationAssertion(Annotation( "GOC:mah") "vesicle localisation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051648") +AnnotationAssertion(rdfs:label "vesicle localization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (establishment of localization in cell) + +AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:dos") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process, occuring in a cell, that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation.") +AnnotationAssertion(Annotation( "GOC:mah") "establishment of localisation in cell") +AnnotationAssertion( "establishment of intracellular localization") +AnnotationAssertion( "establishment of localization within cell") +AnnotationAssertion( "positioning within cell") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "establishment of cellular localization") +AnnotationAssertion( "GO:0051649") +AnnotationAssertion(rdfs:label "establishment of localization in cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectAllValuesFrom( )) + +# Class: (establishment of vesicle localization) + +AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of a vesicle to a specific location.") +AnnotationAssertion(Annotation( "GOC:mah") "establishment of vesicle localisation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051650") +AnnotationAssertion(rdfs:label "establishment of vesicle localization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (maintenance of location in cell) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process in which a substance or cellular entity, such as a protein complex or organelle, is maintained in a specific location within, or in the membrane of, a cell, and is prevented from moving elsewhere.") +AnnotationAssertion( "cellular retention") +AnnotationAssertion( "cellular sequestering") +AnnotationAssertion( "cellular storage") +AnnotationAssertion( "intracellular retention") +AnnotationAssertion( "intracellular sequestering") +AnnotationAssertion( "intracellular storage") +AnnotationAssertion( "maintenance of intracellular localization") +AnnotationAssertion( "maintenance of localization within cell") +AnnotationAssertion( "retention within cell") +AnnotationAssertion( "sequestering within cell") +AnnotationAssertion( "storage within cell") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "maintenance of cellular localization") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "maintenance of localization in cell") +AnnotationAssertion( "GO:0051651") +AnnotationAssertion(rdfs:label "maintenance of location in cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (maintenance of chromosome location) + +AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process in which a chromosome is maintained in a specific location within a cell and prevented from moving elsewhere.") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "maintenance of chromosome localization") +AnnotationAssertion( "GO:0051652") +AnnotationAssertion(rdfs:label "maintenance of chromosome location") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (maintenance of vesicle location) + +AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process in which a vesicle is maintained in a specific location within a cell and prevented from moving elsewhere.") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "maintenance of vesicle localization") +AnnotationAssertion( "GO:0051655") +AnnotationAssertion(rdfs:label "maintenance of vesicle location") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (establishment of organelle localization) + +AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of an organelle to a specific location.") +AnnotationAssertion(Annotation( "GOC:mah") "establishment of organelle localisation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051656") +AnnotationAssertion(rdfs:label "establishment of organelle localization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (maintenance of organelle location) + +AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process in which an organelle is maintained in a specific location within a cell and prevented from moving elsewhere.") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "maintenance of organelle localization") +AnnotationAssertion( "GO:0051657") +AnnotationAssertion(rdfs:label "maintenance of organelle location") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (maintenance of nucleus location) + +AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process in which the nucleus is maintained in a specific location within a cell and prevented from moving elsewhere.") +AnnotationAssertion( "maintenance of cell nucleus location") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "maintenance of nucleus localization") +AnnotationAssertion( "GO:0051658") +AnnotationAssertion(rdfs:label "maintenance of nucleus location") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (localization within membrane) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process in which a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a membrane.") +AnnotationAssertion( "establishment and maintenance of localization in membrane") +AnnotationAssertion( "establishment and maintenance of position in membrane") +AnnotationAssertion(Annotation( "GOC:mah") "localisation within membrane") +AnnotationAssertion( "localization to membrane") +AnnotationAssertion( "positioning within membrane") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051668") +AnnotationAssertion(rdfs:label "localization within membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (localization of cell) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process in which a cell is transported to, and/or maintained in, a specific location.") +AnnotationAssertion( "cell localization") +AnnotationAssertion( "establishment and maintenance of cell localization") +AnnotationAssertion( "establishment and maintenance of localization of cell") +AnnotationAssertion(Annotation( "GOC:mah") "localisation of cell") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051674") +AnnotationAssertion(rdfs:label "localization of cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (establishment of Golgi localization) + +AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of the Golgi to a specific location.") +AnnotationAssertion( "establishment of Golgi apparatus localization") +AnnotationAssertion( "establishment of Golgi body localization") +AnnotationAssertion(Annotation( "GOC:mah") "establishment of Golgi localisation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051683") +AnnotationAssertion(rdfs:label "establishment of Golgi localization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (maintenance of Golgi location) + +AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process in which the Golgi is maintained in a specific location within a cell and prevented from moving elsewhere.") +AnnotationAssertion( "maintenance of Golgi apparatus localization") +AnnotationAssertion( "maintenance of Golgi body localization") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "maintenance of Golgi localization") +AnnotationAssertion( "GO:0051684") +AnnotationAssertion(rdfs:label "maintenance of Golgi location") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + # Class: (response to other organism) AnnotationAssertion(Annotation( "GOC:ai") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from another living organism.") @@ -39766,6 +95020,7 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0051707") AnnotationAssertion(rdfs:label "response to other organism") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) @@ -39780,6 +95035,617 @@ AnnotationAssertion(rdfs:label "cell SubClassOf( ) SubClassOf( ) +# Class: (regulation of cell cycle) + +AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the rate or extent of progression through the cell cycle.") +AnnotationAssertion( "GO:0000074") +AnnotationAssertion( "GO:0007050") +AnnotationAssertion( "GO:0071156") +AnnotationAssertion( "GO:0071157") +AnnotationAssertion( "GO:0071158") +AnnotationAssertion( "GO:0071850") +AnnotationAssertion( "cell cycle modulation") +AnnotationAssertion( "cell cycle regulation") +AnnotationAssertion( "control of cell cycle progression") +AnnotationAssertion( "modulation of cell cycle progression") +AnnotationAssertion( "regulation of cell cycle progression") +AnnotationAssertion( "regulation of progression through cell cycle") +AnnotationAssertion(Annotation( "GOC:mah") "arrest of mitotic cell cycle progression") +AnnotationAssertion( "cell cycle arrest") +AnnotationAssertion( "mitotic cell cycle arrest") +AnnotationAssertion( "negative regulation of cell cycle arrest") +AnnotationAssertion( "positive regulation of cell cycle arrest") +AnnotationAssertion( "regulation of cell cycle arrest") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "cell cycle regulator") +AnnotationAssertion( "tumor suppressor") +AnnotationAssertion( "GO:0051726") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "regulation of cell cycle") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (xanthophyll binding) + +AnnotationAssertion(Annotation( "ISBN:0122146743") "Binding to xanthophylls, any of several neutral yellow to orange carotenoid pigments containing oxygen.") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0051738") +AnnotationAssertion(rdfs:label "xanthophyll binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (sesquiterpene metabolic process) + +AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways involving sesquiterpenes, any of a class of terpenes of the formula C15H24 or a derivative of such a terpene.") +AnnotationAssertion( "sesquiterpene metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051761") +AnnotationAssertion(rdfs:label "sesquiterpene metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (sesquiterpene biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways resulting in the formation of sesquiterpenes, any of a class of terpenes of the formula C15H24 or a derivative of such a terpene.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051762") +AnnotationAssertion(rdfs:label "sesquiterpene biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (sesquiterpene catabolic process) + +AnnotationAssertion(Annotation( "GOC:ai") "The chemical reactions and pathways resulting in the breakdown of sesquiterpenes, any of a class of terpenes of the formula C15H24 or a derivative of such a terpene.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051763") +AnnotationAssertion(rdfs:label "sesquiterpene catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of cell division) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of cell division.") +AnnotationAssertion( "up regulation of cell division") +AnnotationAssertion( "up-regulation of cell division") +AnnotationAssertion( "upregulation of cell division") +AnnotationAssertion( "activation of cell division") +AnnotationAssertion( "stimulation of cell division") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051781") +AnnotationAssertion(rdfs:label "positive regulation of cell division") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of cell division) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of cell division.") +AnnotationAssertion( "down regulation of cell division") +AnnotationAssertion( "down-regulation of cell division") +AnnotationAssertion( "downregulation of cell division") +AnnotationAssertion( "inhibition of cell division") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051782") +AnnotationAssertion(rdfs:label "negative regulation of cell division") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of nuclear division) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051783") +AnnotationAssertion(rdfs:label "regulation of nuclear division") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (negative regulation of nuclear division) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information.") +AnnotationAssertion( "down regulation of nuclear division") +AnnotationAssertion( "down-regulation of nuclear division") +AnnotationAssertion( "downregulation of nuclear division") +AnnotationAssertion( "inhibition of nuclear division") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051784") +AnnotationAssertion(rdfs:label "negative regulation of nuclear division") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of nuclear division) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information.") +AnnotationAssertion( "up regulation of nuclear division") +AnnotationAssertion( "up-regulation of nuclear division") +AnnotationAssertion( "upregulation of nuclear division") +AnnotationAssertion( "activation of nuclear division") +AnnotationAssertion( "stimulation of nuclear division") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051785") +AnnotationAssertion(rdfs:label "positive regulation of nuclear division") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (short-chain fatty acid biosynthetic process) + +AnnotationAssertion(Annotation( "Wikipedia:Fatty_acid_metabolism") "The chemical reactions and pathways resulting in the formation of a fatty acid with an aliphatic tail of less than 6 carbons.") +AnnotationAssertion( "short chain fatty acid biosynthesis") +AnnotationAssertion( "short chain fatty acid biosynthetic process") +AnnotationAssertion( "short-chain fatty acid anabolism") +AnnotationAssertion( "short-chain fatty acid biosynthesis") +AnnotationAssertion( "short-chain fatty acid formation") +AnnotationAssertion( "short-chain fatty acid synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051790") +AnnotationAssertion(rdfs:label "short-chain fatty acid biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of hair follicle development) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of hair follicle development.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051797") +AnnotationAssertion(rdfs:label "regulation of hair follicle development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (positive regulation of hair follicle development) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of hair follicle development.") +AnnotationAssertion( "up regulation of hair follicle development") +AnnotationAssertion( "up-regulation of hair follicle development") +AnnotationAssertion( "upregulation of hair follicle development") +AnnotationAssertion( "activation of hair follicle development") +AnnotationAssertion( "stimulation of hair follicle development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051798") +AnnotationAssertion(rdfs:label "positive regulation of hair follicle development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of hair follicle development) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of hair follicle development.") +AnnotationAssertion( "down regulation of hair follicle development") +AnnotationAssertion( "down-regulation of hair follicle development") +AnnotationAssertion( "downregulation of hair follicle development") +AnnotationAssertion( "inhibition of hair follicle development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051799") +AnnotationAssertion(rdfs:label "negative regulation of hair follicle development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (glycolipid binding) + +AnnotationAssertion(Annotation( "PMID:19635802") "Binding to a glycolipid, any compound containing one or more monosaccharide residues bound by a glycosidic linkage to a hydrophobic group such as an acylglycerol, a sphingoid, a ceramide (N-acylsphingoid) or a prenyl phosphate.") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0051861") +AnnotationAssertion(rdfs:label "glycolipid binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (pigment granule localization) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process in which a pigment granule is transported to, and/or maintained in, a specific location within the cell.") +AnnotationAssertion(Annotation( "GOC:mah") "pigment granule localisation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051875") +AnnotationAssertion(rdfs:label "pigment granule localization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (regulation of cardioblast differentiation) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of cardioblast differentiation, the process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051890") +AnnotationAssertion(rdfs:label "regulation of cardioblast differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of cardioblast differentiation) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of cardioblast differentiation, the process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.") +AnnotationAssertion( "up regulation of cardioblast differentiation") +AnnotationAssertion( "up-regulation of cardioblast differentiation") +AnnotationAssertion( "upregulation of cardioblast differentiation") +AnnotationAssertion( "activation of cardioblast differentiation") +AnnotationAssertion( "stimulation of cardioblast differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051891") +AnnotationAssertion(rdfs:label "positive regulation of cardioblast differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of cardioblast differentiation) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of cardioblast differentiation, the process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.") +AnnotationAssertion( "down regulation of cardioblast differentiation") +AnnotationAssertion( "down-regulation of cardioblast differentiation") +AnnotationAssertion( "downregulation of cardioblast differentiation") +AnnotationAssertion( "inhibition of cardioblast differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051892") +AnnotationAssertion(rdfs:label "negative regulation of cardioblast differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (pigment granule transport) + +AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of pigment granules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion( "pigment granule translocation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051904") +AnnotationAssertion(rdfs:label "pigment granule transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (establishment of pigment granule localization) + +AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of a pigment granule to a specific location.") +AnnotationAssertion(Annotation( "GOC:mah") "establishment of pigment granule localisation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051905") +AnnotationAssertion(rdfs:label "establishment of pigment granule localization") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (regulation of calcium ion transport) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of the directed movement of calcium ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion( "regulation of calcium transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051924") +AnnotationAssertion(rdfs:label "regulation of calcium ion transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of calcium ion transport) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of calcium ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion( "down regulation of calcium ion transport") +AnnotationAssertion( "down-regulation of calcium ion transport") +AnnotationAssertion( "downregulation of calcium ion transport") +AnnotationAssertion( "negative regulation of calcium transport") +AnnotationAssertion( "inhibition of calcium ion transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051926") +AnnotationAssertion(rdfs:label "negative regulation of calcium ion transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of calcium ion transport) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of the directed movement of calcium ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion( "positive regulation of calcium transport") +AnnotationAssertion( "up regulation of calcium ion transport") +AnnotationAssertion( "up-regulation of calcium ion transport") +AnnotationAssertion( "upregulation of calcium ion transport") +AnnotationAssertion( "activation of calcium ion transport") +AnnotationAssertion( "stimulation of calcium ion transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051928") +AnnotationAssertion(rdfs:label "positive regulation of calcium ion transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of sensory perception of pain) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of the sensory perception of pain, the series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051930") +AnnotationAssertion(rdfs:label "regulation of sensory perception of pain") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of sensory perception) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of sensory perception, the series of events required for an organism to receive a sensory stimulus, convert it to a molecular signal, and recognize and characterize the signal.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051931") +AnnotationAssertion(rdfs:label "regulation of sensory perception") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (synaptic transmission, GABAergic) + +AnnotationAssertion(Annotation( "GOC:dos") Annotation( "ISBN:0126603030") "The vesicular release of gamma-aminobutyric acid (GABA). from a presynapse, across a chemical synapse, the subsequent activation of GABA receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.") +AnnotationAssertion( "GABAergic synaptic transmission") +AnnotationAssertion( "synaptic transmission, GABA mediated") +AnnotationAssertion( "synaptic transmission, gamma-aminobutyric acid mediated") +AnnotationAssertion( "synaptic transmission, gamma-aminobutyric acid-ergic") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051932") +AnnotationAssertion(rdfs:label "synaptic transmission, GABAergic") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (catecholamine transport) + +AnnotationAssertion(Annotation( "GOC:ai") Annotation( "ISBN:0198506732") "The directed movement of catecholamines, a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051937") +AnnotationAssertion(rdfs:label "catecholamine transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (L-glutamate import) + +AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:jsg") Annotation( "GOC:mah") "The directed movement of L-glutamate, the L-enantiomer of the anion of 2-aminopentanedioic acid, into a cell or organelle.") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "L-glutamate uptake") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051938") +AnnotationAssertion(rdfs:label "L-glutamate import") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (gamma-aminobutyric acid import) + +AnnotationAssertion(Annotation( "GOC:ai") "The directed movement of gamma-aminobutyric acid (GABA, 4-aminobutyrate) into a cell or organelle.") +AnnotationAssertion( "4-aminobutyrate import") +AnnotationAssertion( "GABA import") +AnnotationAssertion( "gamma-aminobutyrate import") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "gamma-aminobutyric acid uptake") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051939") +AnnotationAssertion(rdfs:label "gamma-aminobutyric acid import") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of amine transport) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051952") +AnnotationAssertion(rdfs:label "regulation of amine transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (negative regulation of amine transport) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion( "down regulation of amine transport") +AnnotationAssertion( "down-regulation of amine transport") +AnnotationAssertion( "downregulation of amine transport") +AnnotationAssertion( "inhibition of amine transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051953") +AnnotationAssertion(rdfs:label "negative regulation of amine transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of amine transport) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion( "up regulation of amine transport") +AnnotationAssertion( "up-regulation of amine transport") +AnnotationAssertion( "upregulation of amine transport") +AnnotationAssertion( "activation of amine transport") +AnnotationAssertion( "stimulation of amine transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051954") +AnnotationAssertion(rdfs:label "positive regulation of amine transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of amino acid transport) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051955") +AnnotationAssertion(rdfs:label "regulation of amino acid transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (negative regulation of amino acid transport) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion( "down regulation of amino acid transport") +AnnotationAssertion( "down-regulation of amino acid transport") +AnnotationAssertion( "downregulation of amino acid transport") +AnnotationAssertion(Annotation( "GOC:mah") "negative regulation of amino acid transmembrane transport") +AnnotationAssertion( "inhibition of amino acid transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051956") +AnnotationAssertion(rdfs:label "negative regulation of amino acid transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (positive regulation of amino acid transport) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion(Annotation( "GOC:mah") "positive regulation of amino acid transmembrane transport") +AnnotationAssertion( "up regulation of amino acid transport") +AnnotationAssertion( "up-regulation of amino acid transport") +AnnotationAssertion( "upregulation of amino acid transport") +AnnotationAssertion( "activation of amino acid transport") +AnnotationAssertion( "stimulation of amino acid transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051957") +AnnotationAssertion(rdfs:label "positive regulation of amino acid transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of nervous system development) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051960") +AnnotationAssertion(rdfs:label "regulation of nervous system development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (negative regulation of nervous system development) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue.") +AnnotationAssertion( "down regulation of nervous system development") +AnnotationAssertion( "down-regulation of nervous system development") +AnnotationAssertion( "downregulation of nervous system development") +AnnotationAssertion( "inhibition of nervous system development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051961") +AnnotationAssertion(rdfs:label "negative regulation of nervous system development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of nervous system development) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates, maintains or increases the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue.") +AnnotationAssertion( "up regulation of nervous system development") +AnnotationAssertion( "up-regulation of nervous system development") +AnnotationAssertion( "upregulation of nervous system development") +AnnotationAssertion( "activation of nervous system development") +AnnotationAssertion( "stimulation of nervous system development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051962") +AnnotationAssertion(rdfs:label "positive regulation of nervous system development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of synapse assembly) + +AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:pr") "Any process that modulates the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse.") +AnnotationAssertion( "regulation of synapse biogenesis") +AnnotationAssertion( "regulation of synaptogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051963") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "regulation of synapse assembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of synapse assembly) + +AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:pr") "Any process that stops, prevents, or reduces the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse.") +AnnotationAssertion( "down regulation of synapse assembly") +AnnotationAssertion( "down-regulation of synapse assembly") +AnnotationAssertion( "downregulation of synapse assembly") +AnnotationAssertion( "negative regulation of synapse biogenesis") +AnnotationAssertion( "negative regulation of synaptogenesis") +AnnotationAssertion( "inhibition of synapse assembly") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051964") +AnnotationAssertion(rdfs:label "negative regulation of synapse assembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (positive regulation of synapse assembly) + +AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:pr") "Any process that activates, maintains or increases the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse.") +AnnotationAssertion( "positive regulation of synapse biogenesis") +AnnotationAssertion( "positive regulation of synaptogenesis") +AnnotationAssertion( "up regulation of synapse assembly") +AnnotationAssertion( "up-regulation of synapse assembly") +AnnotationAssertion( "upregulation of synapse assembly") +AnnotationAssertion( "activation of synapse assembly") +AnnotationAssertion( "stimulation of synapse assembly") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051965") +AnnotationAssertion(rdfs:label "positive regulation of synapse assembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of synaptic transmission, glutamatergic) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051966") +AnnotationAssertion(rdfs:label "regulation of synaptic transmission, glutamatergic") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of synaptic transmission, glutamatergic) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate.") +AnnotationAssertion( "down regulation of synaptic transmission, glutamatergic") +AnnotationAssertion( "down-regulation of synaptic transmission, glutamatergic") +AnnotationAssertion( "downregulation of synaptic transmission, glutamatergic") +AnnotationAssertion( "inhibition of synaptic transmission, glutamatergic") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051967") +AnnotationAssertion(rdfs:label "negative regulation of synaptic transmission, glutamatergic") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of synaptic transmission, glutamatergic) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates, maintains or increases the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate.") +AnnotationAssertion( "up regulation of synaptic transmission, glutamatergic") +AnnotationAssertion( "up-regulation of synaptic transmission, glutamatergic") +AnnotationAssertion( "upregulation of synaptic transmission, glutamatergic") +AnnotationAssertion( "activation of synaptic transmission, glutamatergic") +AnnotationAssertion( "stimulation of synaptic transmission, glutamatergic") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051968") +AnnotationAssertion(rdfs:label "positive regulation of synaptic transmission, glutamatergic") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of transmission of nerve impulse) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation.") +AnnotationAssertion(Annotation( "GOC:dph") "regulation of conduction of nerve impulse") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051969") +AnnotationAssertion(rdfs:label "regulation of transmission of nerve impulse") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (negative regulation of transmission of nerve impulse) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation.") +AnnotationAssertion( "down regulation of transmission of nerve impulse") +AnnotationAssertion( "down-regulation of transmission of nerve impulse") +AnnotationAssertion( "downregulation of transmission of nerve impulse") +AnnotationAssertion(Annotation( "GOC:dph") "negative regulation of conduction of nerve impulse") +AnnotationAssertion( "inhibition of transmission of nerve impulse") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051970") +AnnotationAssertion(rdfs:label "negative regulation of transmission of nerve impulse") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (positive regulation of transmission of nerve impulse) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates, maintains or increases the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation.") +AnnotationAssertion(Annotation( "GOC:dph") "positive regulation of conduction of nerve impulse") +AnnotationAssertion( "up regulation of transmission of nerve impulse") +AnnotationAssertion( "up-regulation of transmission of nerve impulse") +AnnotationAssertion( "upregulation of transmission of nerve impulse") +AnnotationAssertion( "activation of transmission of nerve impulse") +AnnotationAssertion( "stimulation of transmission of nerve impulse") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051971") +AnnotationAssertion(rdfs:label "positive regulation of transmission of nerve impulse") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of chromosome segregation) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that modulates the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051983") +AnnotationAssertion(rdfs:label "regulation of chromosome segregation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of chromosome segregation) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that activates or increases the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets.") +AnnotationAssertion( "up regulation of chromosome segregation") +AnnotationAssertion( "up-regulation of chromosome segregation") +AnnotationAssertion( "upregulation of chromosome segregation") +AnnotationAssertion( "activation of chromosome segregation") +AnnotationAssertion( "stimulation of chromosome segregation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051984") +AnnotationAssertion(rdfs:label "positive regulation of chromosome segregation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of chromosome segregation) + +AnnotationAssertion(Annotation( "GOC:ai") "Any process that stops, prevents, or reduces the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets.") +AnnotationAssertion( "down regulation of chromosome segregation") +AnnotationAssertion( "down-regulation of chromosome segregation") +AnnotationAssertion( "downregulation of chromosome segregation") +AnnotationAssertion( "inhibition of chromosome segregation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0051985") +AnnotationAssertion(rdfs:label "negative regulation of chromosome segregation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (imidazole-containing compound metabolic process) AnnotationAssertion(Annotation( "GOC:curators") "The chemical reactions and pathways involving imidazoles, five-membered organic heterocycle containing two nitrogen atoms at positions 1 and 3, or any of its derivatives; compounds containing an imidazole skeleton.") @@ -39787,12 +95653,321 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0052803") AnnotationAssertion(rdfs:label "imidazole-containing compound metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) SubClassOf( ) +# Class: (imidazole-containing compound catabolic process) + +AnnotationAssertion(Annotation( "GOC:curators") "The chemical reactions and pathways resulting in the breakdown of imidazoles, five-membered organic heterocycle containing two nitrogen atoms at positions 1 and 3, or any of its derivatives; compounds containing an imidazole skeleton.") +AnnotationAssertion( "imidazole breakdown") +AnnotationAssertion( "imidazole catabolism") +AnnotationAssertion( "imidazole degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0052805") +AnnotationAssertion(rdfs:label "imidazole-containing compound catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (muscle cell development) + +AnnotationAssertion(Annotation( "CL:0000187") Annotation( "GOC:devbiol") "The process whose specific outcome is the progression of a muscle cell over time, from its formation to the mature structure. Muscle cell development does not include the steps involved in committing an unspecified cell to the muscle cell fate.") +AnnotationAssertion( "GO:0048747") +AnnotationAssertion( "muscle fiber development") +AnnotationAssertion( "muscle fibre development") +AnnotationAssertion( "myofiber development") +AnnotationAssertion( "myofibre development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0055001") +AnnotationAssertion(rdfs:label "muscle cell development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (striated muscle cell development) + +AnnotationAssertion(Annotation( "CL:0000737") Annotation( "GOC:devbiol") "The process whose specific outcome is the progression of a striated muscle cell over time, from its formation to the mature structure. Striated muscle cells contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0055002") +AnnotationAssertion(rdfs:label "striated muscle cell development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cardiac myofibril assembly) + +AnnotationAssertion(Annotation( "GOC:devbiol") "The process whose specific outcome is the progression of the cardiac myofibril over time, from its formation to the mature structure. A cardiac myofibril is a myofibril specific to cardiac muscle cells.") +AnnotationAssertion( "cardiac myofibril development") +AnnotationAssertion( "cardiac myofibril morphogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "heart myofibril assembly") +AnnotationAssertion( "GO:0055003") +AnnotationAssertion(rdfs:label "cardiac myofibril assembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cardiac cell development) + +AnnotationAssertion(Annotation( "GOC:devbiol") "The process whose specific outcome is the progression of a cardiac cell over time, from its formation to the mature state. A cardiac cell is a cell that will form part of the cardiac organ of an individual.") +AnnotationAssertion(Annotation( "GOC:dph") "cardiocyte development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "heart cell development") +AnnotationAssertion( "GO:0055006") +AnnotationAssertion(rdfs:label "cardiac cell development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cardiac muscle cell differentiation) + +AnnotationAssertion(Annotation( "GOC:devbiol") Annotation( "GOC:mtg_heart") "The process in which a cardiac muscle precursor cell acquires specialized features of a cardiac muscle cell. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction.") +AnnotationAssertion( "cardiomyocyte differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "heart muscle cell differentiation") +AnnotationAssertion( "GO:0055007") +AnnotationAssertion(rdfs:label "cardiac muscle cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cardiac muscle tissue morphogenesis) + +AnnotationAssertion(Annotation( "GOC:devbiol") "The process in which the anatomical structures of cardiac muscle tissue are generated and organized.") +AnnotationAssertion(Annotation( "GOC:mtg_heart") "myocardium morphogenesis") +AnnotationAssertion( "heart muscle morphogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0055008") +AnnotationAssertion(rdfs:label "cardiac muscle tissue morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (atrial cardiac muscle tissue morphogenesis) + +AnnotationAssertion(Annotation( "GOC:devbiol") "The process in which the anatomical structure of cardiac atrium muscle is generated and organized.") +AnnotationAssertion( "atrial heart muscle morphogenesis") +AnnotationAssertion(Annotation( "GOC:mtg_heart") "atrial myocardium morphogenesis") +AnnotationAssertion( "cardiac atrium muscle morphogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0055009") +AnnotationAssertion(rdfs:label "atrial cardiac muscle tissue morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (ventricular cardiac muscle tissue morphogenesis) + +AnnotationAssertion(Annotation( "GOC:devbiol") "The process in which the anatomical structures of cardiac ventricle muscle is generated and organized.") +AnnotationAssertion( "cardiac ventricle muscle morphogenesis") +AnnotationAssertion( "ventricular heart muscle morphogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0055010") +AnnotationAssertion(rdfs:label "ventricular cardiac muscle tissue morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cardiac muscle cell development) + +AnnotationAssertion(Annotation( "GOC:devbiol") Annotation( "GOC:mtg_heart") "The process whose specific outcome is the progression of a cardiac muscle cell over time, from its formation to the mature state.") +AnnotationAssertion( "GO:0048739") +AnnotationAssertion( "cardiac muscle fiber development") +AnnotationAssertion( "cardiac muscle fibre development") +AnnotationAssertion(Annotation( "GOC:mtg_muscle") "cardiomyocyte cell development") +AnnotationAssertion( "heart muscle cell development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "heart muscle fiber development") +AnnotationAssertion( "GO:0055013") +AnnotationAssertion(rdfs:label "cardiac muscle cell development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (hypochord development) + +AnnotationAssertion(Annotation( "GOC:devbiol") Annotation( "GOC:lb") "The process whose specific outcome is the progression of the hypochord over time, from its formation to the mature structure. The hypochord is a transient rod-like structure in the embryos of fish, lampreys and amphibians that is located immediately ventral to the notochord. The hypochord may play a role in positioning the dorsal aorta.") +AnnotationAssertion( "subnotochordal rod development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0055016") +AnnotationAssertion(rdfs:label "hypochord development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (cardiac muscle tissue growth) + +AnnotationAssertion(Annotation( "GOC:devbiol") "The increase in size or mass of a cardiac muscle, where the increase in size or mass has the specific outcome of the progression of the organism over time from one condition to another.") +AnnotationAssertion( "heart muscle growth") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0055017") +AnnotationAssertion(rdfs:label "cardiac muscle tissue growth") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (regulation of cardiac muscle fiber development) + +AnnotationAssertion(Annotation( "GOC:vk") "Any process that modulates the frequency, rate or extent of cardiac muscle fiber development.") +AnnotationAssertion( "regulation of cardiac muscle fibre development") +AnnotationAssertion( "regulation of heart muscle fiber development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0055018") +AnnotationAssertion(rdfs:label "regulation of cardiac muscle fiber development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (negative regulation of cardiac muscle fiber development) + +AnnotationAssertion(Annotation( "GOC:vk") "Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle fiber development.") +AnnotationAssertion( "down regulation of cardiac muscle fiber development") +AnnotationAssertion( "down-regulation of cardiac muscle fiber development") +AnnotationAssertion( "downregulation of cardiac muscle fiber development") +AnnotationAssertion( "negative regulation of cardiac muscle fibre development") +AnnotationAssertion( "inhibition of cardiac muscle fiber development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "negative regulation of heart muscle fiber development") +AnnotationAssertion( "GO:0055019") +AnnotationAssertion(rdfs:label "negative regulation of cardiac muscle fiber development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (positive regulation of cardiac muscle fiber development) + +AnnotationAssertion(Annotation( "GOC:vk") "Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle fiber development.") +AnnotationAssertion( "positive regulation of cardiac muscle fibre development") +AnnotationAssertion( "positive regulation of heart muscle fiber development") +AnnotationAssertion( "up regulation of cardiac muscle fiber development") +AnnotationAssertion( "up-regulation of cardiac muscle fiber development") +AnnotationAssertion( "upregulation of cardiac muscle fiber development") +AnnotationAssertion( "activation of cardiac muscle fiber development") +AnnotationAssertion( "stimulation of cardiac muscle fiber development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0055020") +AnnotationAssertion(rdfs:label "positive regulation of cardiac muscle fiber development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (regulation of cardiac muscle tissue growth) + +AnnotationAssertion(Annotation( "GOC:vk") "Any process that modulates the frequency, rate or extent of cardiac muscle growth.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0055021") +AnnotationAssertion(rdfs:label "regulation of cardiac muscle tissue growth") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (negative regulation of cardiac muscle tissue growth) + +AnnotationAssertion(Annotation( "GOC:vk") "Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle growth.") +AnnotationAssertion( "down regulation of cardiac muscle growth") +AnnotationAssertion( "down-regulation of cardiac muscle growth") +AnnotationAssertion( "downregulation of cardiac muscle growth") +AnnotationAssertion( "inhibition of cardiac muscle growth") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "negative regulation of heart muscle growth") +AnnotationAssertion( "GO:0055022") +AnnotationAssertion(rdfs:label "negative regulation of cardiac muscle tissue growth") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (positive regulation of cardiac muscle tissue growth) + +AnnotationAssertion(Annotation( "GOC:vk") "Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle growth.") +AnnotationAssertion( "positive regulation of heart muscle growth") +AnnotationAssertion( "up regulation of cardiac muscle growth") +AnnotationAssertion( "up-regulation of cardiac muscle growth") +AnnotationAssertion( "upregulation of cardiac muscle growth") +AnnotationAssertion( "activation of cardiac muscle growth") +AnnotationAssertion( "stimulation of cardiac muscle growth") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0055023") +AnnotationAssertion(rdfs:label "positive regulation of cardiac muscle tissue growth") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of cardiac muscle tissue development) + +AnnotationAssertion(Annotation( "GOC:vk") "Any process that modulates the frequency, rate or extent of cardiac muscle tissue development.") +AnnotationAssertion( "regulation of heart muscle development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0055024") +AnnotationAssertion(rdfs:label "regulation of cardiac muscle tissue development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of cardiac muscle tissue development) + +AnnotationAssertion(Annotation( "GOC:vk") "Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle tissue development.") +AnnotationAssertion( "positive regulation of heart muscle development") +AnnotationAssertion( "up regulation of cardiac muscle development") +AnnotationAssertion( "up-regulation of cardiac muscle development") +AnnotationAssertion( "upregulation of cardiac muscle development") +AnnotationAssertion( "activation of cardiac muscle development") +AnnotationAssertion( "stimulation of cardiac muscle development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0055025") +AnnotationAssertion(rdfs:label "positive regulation of cardiac muscle tissue development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of cardiac muscle tissue development) + +AnnotationAssertion(Annotation( "GOC:vk") "Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle tissue development.") +AnnotationAssertion( "down regulation of cardiac muscle development") +AnnotationAssertion( "down-regulation of cardiac muscle development") +AnnotationAssertion( "downregulation of cardiac muscle development") +AnnotationAssertion( "negative regulation of heart muscle development") +AnnotationAssertion( "inhibition of cardiac muscle development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0055026") +AnnotationAssertion(rdfs:label "negative regulation of cardiac muscle tissue development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (neuroblast division) + +AnnotationAssertion(Annotation( "PMID:11163136") Annotation( "PMID:11250167") "The process resulting in the physical partitioning and separation of a neuroblast into daughter cells. A neuroblast is any cell that will divide and give rise to a neuron.") +AnnotationAssertion( "neuroblast cell division") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0055057") +AnnotationAssertion(rdfs:label "neuroblast division") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (asymmetric neuroblast division) + +AnnotationAssertion(Annotation( "GOC:dph") "The process resulting in the physical partitioning and separation of a neuroblast into two daughter cells with different developmental potentials.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0055059") +AnnotationAssertion(rdfs:label "asymmetric neuroblast division") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (phosphate ion homeostasis) + +AnnotationAssertion(Annotation( "GOC:jid") Annotation( "GOC:mah") "Any process involved in the maintenance of an internal steady state of phosphate ions within an organism or cell.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0055062") +AnnotationAssertion(rdfs:label "phosphate ion homeostasis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (sulfate ion homeostasis) + +AnnotationAssertion(Annotation( "GOC:jid") Annotation( "GOC:mah") "Any process involved in the maintenance of an internal steady state of sulfate ions within an organism or cell.") +AnnotationAssertion( "GO:0080174") +AnnotationAssertion( "sulfate homeostasis") +AnnotationAssertion( "sulphate ion homeostasis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0055063") +AnnotationAssertion(rdfs:label "sulfate ion homeostasis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (calcium ion homeostasis) AnnotationAssertion(Annotation( "GOC:ceb") Annotation( "GOC:jid") Annotation( "GOC:mah") "Any process involved in the maintenance of an internal steady state of calcium ions within an organism or cell.") @@ -39800,6 +95975,7 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0055074") AnnotationAssertion(rdfs:label "calcium ion homeostasis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (sodium ion homeostasis) @@ -39807,6 +95983,7 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:0055078") AnnotationAssertion(rdfs:label "sodium ion homeostasis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (monoatomic cation homeostasis) @@ -39816,6 +95993,142 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0055080") AnnotationAssertion(rdfs:label "monoatomic cation homeostasis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (intracellular chemical homeostasis) + +AnnotationAssertion(Annotation( "GOC:isa_complete") Annotation( "GOC:jid") "A homeostatic process involved in the maintenance of a steady state level of a chemical within a cell.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/24514"^^xsd:anyURI) +AnnotationAssertion( "cellular chemical homeostasis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0055082") +AnnotationAssertion(rdfs:label "intracellular chemical homeostasis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (transmembrane transport) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:jid") "The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2015-10-21T13:22:47Z") +AnnotationAssertion( "GO:0090662") +AnnotationAssertion( "membrane transport") +AnnotationAssertion( "ATP hydrolysis coupled transmembrane transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0055085") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:comment "Transmembrane transport is the transport of a solute across a lipid bilayer. Note that transport through the nuclear pore complex is not transmembrane because the nuclear membrane is a double membrane and is not traversed. For transport through the nuclear pore, consider instead the term 'nucleocytoplasmic transport ; GO:0006913' and its children. Note also that this term is not intended for use in annotating lateral movement within membranes.") +AnnotationAssertion(rdfs:label "transmembrane transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (nucleobase-containing small molecule metabolic process) + +AnnotationAssertion(Annotation( "GOC:vw") "The cellular chemical reactions and pathways involving a nucleobase-containing small molecule: a nucleobase, a nucleoside, or a nucleotide.") +AnnotationAssertion( "nucleobase, nucleoside and nucleotide metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "nucleobase, nucleoside and nucleotide metabolic process") +AnnotationAssertion( "GO:0055086") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "nucleobase-containing small molecule metabolic process") +SubClassOf( ) +SubClassOf( ) + +# Class: (lipid homeostasis) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:rl") "Any process involved in the maintenance of an internal steady state of lipid within an organism or cell.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0055088") +AnnotationAssertion(rdfs:label "lipid homeostasis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (fatty acid homeostasis) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:rl") "Any process involved in the maintenance of an internal steady state of fatty acid within an organism or cell.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0055089") +AnnotationAssertion(rdfs:label "fatty acid homeostasis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (phospholipid homeostasis) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:rl") "Any process involved in the maintenance of an internal steady state of phospholipid within an organism or cell.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0055091") +AnnotationAssertion(rdfs:label "phospholipid homeostasis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (response to lipoprotein particle) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:rl") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoprotein particle stimulus.") +AnnotationAssertion(Annotation( "GOC:dos") "response to lipoprotein particle stimulus") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0055094") +AnnotationAssertion(rdfs:label "response to lipoprotein particle") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (Golgi to secretory granule transport) + +AnnotationAssertion(Annotation( "GOC:curators") "The directed movement of proteins from the Golgi to a secretory granule. The secretory granule is a membrane-bounded particle, usually protein, formed in the granular endoplasmic reticulum and the Golgi complex.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0055107") +AnnotationAssertion(rdfs:label "Golgi to secretory granule transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (Golgi to transport vesicle transport) + +AnnotationAssertion(Annotation( "GOC:jid") "The directed movement of proteins from the Golgi to a transport vesicle. Continuously secreted proteins are sorted into transport vesicles that fuse with the plasma membrane, releasing their contents by exocytosis.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0055108") +AnnotationAssertion(rdfs:label "Golgi to transport vesicle transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (ingression involved in gastrulation with mouth forming second) + +AnnotationAssertion(Annotation( "ISBN:0878932437") "The migration of individual cells into the embryo involved in deuterostomic gastrulation.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0055111") +AnnotationAssertion(rdfs:label "ingression involved in gastrulation with mouth forming second") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of cardiac muscle contraction) + +AnnotationAssertion(Annotation( "GOC:ecd") "Any process that modulates the frequency, rate or extent of cardiac muscle contraction.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0055117") +AnnotationAssertion(rdfs:label "regulation of cardiac muscle contraction") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of cardiac muscle contraction) + +AnnotationAssertion(Annotation( "GOC:ecd") "Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle contraction.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0055118") +AnnotationAssertion(rdfs:label "negative regulation of cardiac muscle contraction") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (digestive system development) + +AnnotationAssertion(Annotation( "GOC:jid") "The process whose specific outcome is the progression of the digestive system over time, from its formation to the mature structure. The digestive system is the entire structure in which digestion takes place. Digestion is all of the physical, chemical, and biochemical processes carried out by multicellular organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0055123") +AnnotationAssertion(rdfs:label "digestive system development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) # Class: (vibrational conductance of sound to the inner ear) @@ -39853,6 +96166,214 @@ AnnotationAssertion( "linear vestibuloocular reflex") SubClassOf( ) +# Class: (Sertoli cell differentiation) + +AnnotationAssertion(Annotation( "GOC:dph") "The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a Sertoli cell. A Sertoli cell is a supporting cell projecting inward from the basement membrane of seminiferous tubules.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060008") +AnnotationAssertion(rdfs:label "Sertoli cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (Sertoli cell development) + +AnnotationAssertion(Annotation( "GOC:dph") "The process whose specific outcome is the progression of a Sertoli cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a Sertoli cell fate.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060009") +AnnotationAssertion(rdfs:label "Sertoli cell development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (Sertoli cell proliferation) + +AnnotationAssertion(Annotation( "GOC:dph") "The multiplication or reproduction of Sertoli cells, resulting in the expansion of the Sertoli cell population. A Sertoli cell is a supporting cell projecting inward from the basement membrane of seminiferous tubules.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060011") +AnnotationAssertion(rdfs:label "Sertoli cell proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (granulosa cell differentiation) + +AnnotationAssertion(Annotation( "GOC:dph") "The process in which a relatively unspecialized cell acquires the specialized features of a granulosa cell, a supporting cell for the developing female gamete in the ovary of mammals.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060014") +AnnotationAssertion(rdfs:label "granulosa cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (granulosa cell development) + +AnnotationAssertion(Annotation( "GOC:dph") "The process whose specific outcome is the progression of a granulosa cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a granulosa cell fate.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060016") +AnnotationAssertion(rdfs:label "granulosa cell development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (parathyroid gland development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "ISBN:0721662544") "The process whose specific outcome is the progression of the parathyroid gland over time, from its formation to the mature structure. The parathyroid gland is an organ specialised for secretion of parathyroid hormone.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060017") +AnnotationAssertion(rdfs:label "parathyroid gland development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (radial glial cell differentiation) + +AnnotationAssertion(Annotation( "GOC:dph") "The process in which neuroepithelial cells of the neural tube give rise to radial glial cells, specialized bipotential progenitors cells of the brain. Differentiation includes the processes involved in commitment of a cell to a specific fate.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060019") +AnnotationAssertion(rdfs:label "radial glial cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (roof of mouth development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "ISBN:0721662544") "The biological process whose specific outcome is the progression of the roof of the mouth from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The roof of the mouth is the partition that separates the nasal and oral cavities.") +AnnotationAssertion(Annotation( "ISBN:0721662544") "palatum development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060021") +AnnotationAssertion(rdfs:label "roof of mouth development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (hard palate development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "ISBN:0721662544") "The biological process whose specific outcome is the progression of the hard palate from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. The hard palate is the anterior portion of the palate consisting of bone and mucous membranes.") +AnnotationAssertion(Annotation( "ISBN:0721662544") "palatum durum development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060022") +AnnotationAssertion(rdfs:label "hard palate development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (soft palate development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "ISBN:0721662544") "The biological process whose specific outcome is the progression of the soft palate from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. The soft palate is the posterior portion of the palate extending from the posterior edge of the hard palate.") +AnnotationAssertion( ) +AnnotationAssertion(Annotation( "ISBN:0721662544") "palatum molle development") +AnnotationAssertion(Annotation( "ISBN:0721662544") "velum palatum development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060023") +AnnotationAssertion(rdfs:label "soft palate development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses( ObjectSomeValuesFrom( )) + +# Class: (pharyngeal system development) + +AnnotationAssertion(Annotation( "GOC:dph") "The process whose specific outcome is the progression of the pharyngeal system over time, from its formation to the mature structure. The pharyngeal system is a transient embryonic complex that is specific to vertebrates. It comprises the pharyngeal arches, bulges of tissues of mesoderm and neural crest derivation through which pass nerves and pharyngeal arch arteries. The arches are separated internally by pharyngeal pouches, evaginations of foregut endoderm, and externally by pharyngeal clefts, invaginations of surface ectoderm. The development of the system ends when the stucture it contributes to are forming: the thymus, thyroid, parathyroids, maxilla, mandible, aortic arch, cardiac outflow tract, external and middle ear.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060037") +AnnotationAssertion(rdfs:label "pharyngeal system development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cardiac muscle cell proliferation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:rph") Annotation( "PMID:11161571") "The expansion of a cardiac muscle cell population by cell division.") +AnnotationAssertion( "cardiac myocyte proliferation") +AnnotationAssertion( "heart muscle cell proliferation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:10074473") "cardiomyocyte proliferation") +AnnotationAssertion( "GO:0060038") +AnnotationAssertion(rdfs:label "cardiac muscle cell proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (pericardium development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:rph") Annotation( "PMID:15138308") Annotation( "PMID:16376438") "The process whose specific outcome is the progression of the pericardium over time, from its formation to the mature structure. The pericardium is a double-walled sac that contains the heart and the roots of the aorta, vena cava and the pulmonary artery.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060039") +AnnotationAssertion(rdfs:label "pericardium development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (retinal bipolar neuron differentiation) + +AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:bf") Annotation( "GOC:dph") Annotation( "GOC:tb") "The process in which a relatively unspecialized cell acquires specialized features of a bipolar cell, the last neuron to be generated in the retina.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060040") +AnnotationAssertion(rdfs:label "retinal bipolar neuron differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (retina development in camera-type eye) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:dph") Annotation( "ISBN:0815340729") "The process whose specific outcome is the progression of the retina over time, from its formation to the mature structure. The retina is the innermost layer or coating at the back of the eyeball, which is sensitive to light and in which the optic nerve terminates.") +AnnotationAssertion( "GO:0002073") +AnnotationAssertion( "retina development in camera-style eye") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "retinal development") +AnnotationAssertion( "GO:0060041") +AnnotationAssertion(rdfs:label "retina development in camera-type eye") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (retina morphogenesis in camera-type eye) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:dph") Annotation( "GOC:mtg_sensu") "The process in which the anatomical structure of the retina is generated and organized.") +AnnotationAssertion( "retina morphogenesis in camera-style eye") +AnnotationAssertion( "retinogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060042") +AnnotationAssertion(rdfs:label "retina morphogenesis in camera-type eye") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (regulation of cardiac muscle cell proliferation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:rph") "Any process that modulates the frequency, rate or extent of cardiac muscle cell proliferation.") +AnnotationAssertion( "regulation of heart muscle cell proliferation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") "regulation of cardiomyocyte proliferation") +AnnotationAssertion( "GO:0060043") +AnnotationAssertion(rdfs:label "regulation of cardiac muscle cell proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (negative regulation of cardiac muscle cell proliferation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:rph") "Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle cell proliferation.") +AnnotationAssertion( "negative regulation of heart muscle cell proliferation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060044") +AnnotationAssertion(rdfs:label "negative regulation of cardiac muscle cell proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (positive regulation of cardiac muscle cell proliferation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:rph") "Any process that activates or increases the frequency, rate or extent of cardiac muscle cell proliferation.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "positive regulation of heart muscle cell proliferation") +AnnotationAssertion( "GO:0060045") +AnnotationAssertion(rdfs:label "positive regulation of cardiac muscle cell proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + # Class: (heart contraction) AnnotationAssertion(Annotation( "GOC:dph") "The multicellular organismal process in which the heart decreases in volume in a characteristic way to propel blood through the body.") @@ -39872,9 +96393,84 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0060048") AnnotationAssertion(rdfs:label "cardiac muscle contraction") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (positive regulation of epithelial cell proliferation involved in wound healing) + +AnnotationAssertion(Annotation( "GOC:dph") "Any process that activates or increases the rate or extent of epithelial cell proliferation, contributing to the restoration of integrity to a damaged tissue following an injury.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060054") +AnnotationAssertion(rdfs:label "positive regulation of epithelial cell proliferation involved in wound healing") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (angiogenesis involved in wound healing) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:15039218") "Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to a damaged tissue, following an injury.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060055") +AnnotationAssertion(rdfs:label "angiogenesis involved in wound healing") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (Spemann organizer formation) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:dph") "Formation of the specialized region on the dorsalmost side of the embryo that acts as the main signaling center establishing the vertebrate body plan.") +AnnotationAssertion( "Spemann's organizer formation") +AnnotationAssertion( "Spemann-Mangold organizer formation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060061") +AnnotationAssertion(rdfs:label "Spemann organizer formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (uterus development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:ebc") "The reproductive developmental process whose specific outcome is the progression of the uterus over time, from its formation to the mature structure.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "Mullerian tract development") +AnnotationAssertion( "GO:0060065") +AnnotationAssertion(rdfs:label "uterus development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (oviduct development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:ebc") Annotation( "http://www.thefreedictionary.com/oviduct") "The reproductive developmental process whose specific outcome is the progression of an oviduct over time, from its formation to the mature structure. An oviduct is a tube through which an ova passes from the ovary to the uterus, or from the ovary to the outside of the organism.") +AnnotationAssertion(Annotation( "GOC:bf") "fallopian tube development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "Mullerian tract development") +AnnotationAssertion( "GO:0060066") +AnnotationAssertion(rdfs:label "oviduct development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (cervix development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:ebc") "The reproductive developmental process whose specific outcome is the progression of the cervix over time, from its formation to the mature structure.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "Mullerian tract development") +AnnotationAssertion( "GO:0060067") +AnnotationAssertion(rdfs:label "cervix development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (vagina development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:ebc") "The reproductive developmental process whose specific outcome is the progression of the vagina over time, from its formation to the mature structure.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060068") +AnnotationAssertion(rdfs:label "vagina development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + # Class: (micturition) AnnotationAssertion(Annotation( "GOC:dph") "The regulation of body fluids process in which parasympathetic nerves stimulate the bladder wall muscle to contract and expel urine from the body.") @@ -39887,6 +96483,37 @@ AnnotationAssertion(rdfs:label "mict SubClassOf( ) SubClassOf( ) +# Class: (excitatory synapse) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:ef") "A synapse in which an action potential in the presynaptic cell increases the probability of an action potential occurring in the postsynaptic cell.") +AnnotationAssertion( "Wikipedia:Excitatory_synapse") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0060076") +AnnotationAssertion(rdfs:label "excitatory synapse") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of postsynaptic membrane potential) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:ef") "Any process that modulates the potential difference across a post-synaptic membrane.") +AnnotationAssertion( "regulation of post-synaptic membrane potential") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060078") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "regulation of postsynaptic membrane potential") +SubClassOf( ) + +# Class: (excitatory postsynaptic potential) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:ef") "A process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential.") +AnnotationAssertion( "regulation of excitatory post-synaptic membrane potential") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "regulation of EPSP") +AnnotationAssertion( "GO:0060079") +AnnotationAssertion(rdfs:label "excitatory postsynaptic potential") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (eye blink reflex) AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:2913208") "The reflex process in which a mechanical stimulus applied to the eye elicits a response of the eyelid closing.") @@ -39896,6 +96523,277 @@ AnnotationAssertion( "eye blink reflex") SubClassOf( ) +# Class: (smooth muscle contraction involved in micturition) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:15827347") "The process leading to shortening and/or development of tension in the urinary bladder smooth muscle tissue involved in the expulsion urine from the body.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "smooth muscle contraction involved in urination") +AnnotationAssertion(Annotation( "GOC:dph") "urinary bladder smooth muscle contraction involved in micturition") +AnnotationAssertion( "GO:0060083") +AnnotationAssertion(rdfs:label "smooth muscle contraction involved in micturition") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (synaptic transmission involved in micturition) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:15827347") "The process of communication from a neuron to a smooth muscle in the bladder that contributes to the expulsion of urine from the body.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "synaptic transmission involved in urination") +AnnotationAssertion( "GO:0060084") +AnnotationAssertion(rdfs:label "synaptic transmission involved in micturition") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (molecular transducer activity) + +AnnotationAssertion(Annotation( "GOC:dos") Annotation( "GOC:pdt") "A compound molecular function in which an effector function is controlled by one or more regulatory components.") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0060089") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "molecular transducer activity") +SubClassOf( ) + +# Class: (serotonin secretion, neurotransmission) + +AnnotationAssertion(Annotation( "GOC:dph") "The regulated release of serotonin by a cell, in which released serotonin acts as a neurotransmitter.") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:tb") "serotonin release, neurotransmission") +AnnotationAssertion( "GO:0060096") +AnnotationAssertion(rdfs:label "serotonin secretion, neurotransmission") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (inner ear receptor cell differentiation) + +AnnotationAssertion(Annotation( "GOC:dph") "The process in which relatively unspecialized cells, acquire specialized structural and/or functional features of inner ear receptor cells. Inner ear receptor cells are mechanorecptors found in the inner ear responsible for transducing signals involved in balance and sensory perception of sound.") +AnnotationAssertion( "inner ear hair cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060113") +AnnotationAssertion(rdfs:label "inner ear receptor cell differentiation") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (vestibular receptor cell differentiation) + +AnnotationAssertion(Annotation( "GOC:dph") "The process in which a relatively unspecialized cell acquires specialized features of a vestibular hair cell.") +AnnotationAssertion( "vestibular hair cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060114") +AnnotationAssertion(rdfs:label "vestibular receptor cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (vestibular receptor cell morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that alters the size or shape of a vestibular receptor cell.") +AnnotationAssertion( "vestibular hair cell morphogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060116") +AnnotationAssertion(rdfs:label "vestibular receptor cell morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (auditory receptor cell development) + +AnnotationAssertion(Annotation( "GOC:dph") "The process whose specific outcome is the progression of an auditory receptor cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.") +AnnotationAssertion( "auditory hair cell development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060117") +AnnotationAssertion(rdfs:label "auditory receptor cell development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (vestibular receptor cell development) + +AnnotationAssertion(Annotation( "GOC:dph") "The process whose specific outcome is the progression of a vestibular receptor cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.") +AnnotationAssertion( "vestibular hair cell development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060118") +AnnotationAssertion(rdfs:label "vestibular receptor cell development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (inner ear receptor cell development) + +AnnotationAssertion(Annotation( "GOC:dph") "The process whose specific outcome is the progression of an inner ear receptor cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.") +AnnotationAssertion( "inner ear hair cell development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060119") +AnnotationAssertion(rdfs:label "inner ear receptor cell development") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (regulation of growth hormone secretion) + +AnnotationAssertion(Annotation( "GOC:dph") "Any process that modulates the frequency, rate or extent of the regulated release of growth hormone from a cell.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060123") +AnnotationAssertion(rdfs:label "regulation of growth hormone secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of growth hormone secretion) + +AnnotationAssertion(Annotation( "GOC:dph") "Any process that increases the frequency, rate or extent of the regulated release of growth hormone from a cell.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060124") +AnnotationAssertion(rdfs:label "positive regulation of growth hormone secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of growth hormone secretion) + +AnnotationAssertion(Annotation( "GOC:dph") "Any process that decreases or stops the frequency, rate or extent of the regulated release of growth hormone from a cell.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060125") +AnnotationAssertion(rdfs:label "negative regulation of growth hormone secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (somatotropin secreting cell differentiation) + +AnnotationAssertion(Annotation( "GOC:dph") "The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a somatotropin secreting cell. A somatotropin secreting cell is an acidophilic cell of the anterior pituitary that produces growth hormone, somatotropin.") +AnnotationAssertion( "growth hormone secreting cell differentiation") +AnnotationAssertion( "somatotrophin secreting cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "somatotrope differentiation") +AnnotationAssertion( "somatotroph differentiation") +AnnotationAssertion( "somatotropic cell differentiation") +AnnotationAssertion( "somatrophic cell differentiation") +AnnotationAssertion( "GO:0060126") +AnnotationAssertion(rdfs:label "somatotropin secreting cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (prolactin secreting cell differentiation) + +AnnotationAssertion(Annotation( "GOC:dph") "The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a prolactin secreting cell. A prolactin secreting cell is an acidophilic cell of the anterior pituitary that produces prolactin.") +AnnotationAssertion( "epsilon-acidophil differentiation") +AnnotationAssertion( "lactotrope differentiation") +AnnotationAssertion( "lactotroph differentiation") +AnnotationAssertion( "lactotropic cell differentiation") +AnnotationAssertion( "mammotrope differentiation") +AnnotationAssertion( "mammotroph differentiation") +AnnotationAssertion( "mammotrophic cell differentiation") +AnnotationAssertion( "mammotropic cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060127") +AnnotationAssertion(rdfs:label "prolactin secreting cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (corticotropin hormone secreting cell differentiation) + +AnnotationAssertion(Annotation( "GOC:dph") "The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a corticotropic hormone secreting cell. An corticotropic hormone secreting cell is a basophil cell of the anterior pituitary that produces corticotropin.") +AnnotationAssertion( "adrenocorticotrophic hormone secreting cell differentiation") +AnnotationAssertion(Annotation( "GOC:dph") "adrenocorticotropic hormone secreting cell differentiation") +AnnotationAssertion( "corticotrope differentiation") +AnnotationAssertion( "corticotroph differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "corticotrophin hormone secreting cell differentiation") +AnnotationAssertion( "GO:0060128") +AnnotationAssertion(rdfs:label "corticotropin hormone secreting cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (corticotropin hormone secreting cell development) + +AnnotationAssertion(Annotation( "GOC:dph") "The process whose specific outcome is the progression of a corticotropic hormone secreting cell over time, from its formation to the mature structure. An corticotropic hormone secreting cell is a basophil cell of the anterior pituitary that produces corticotropin.") +AnnotationAssertion( "adrenocorticotrophic hormone secreting cell development") +AnnotationAssertion(Annotation( "GOC:dph") "adrenocorticotropic hormone secreting cell development") +AnnotationAssertion( "corticotrope development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "corticotroph development") +AnnotationAssertion( "corticotrophin hormone secreting cell development") +AnnotationAssertion( "GO:0060131") +AnnotationAssertion(rdfs:label "corticotropin hormone secreting cell development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (prolactin secreting cell development) + +AnnotationAssertion(Annotation( "GOC:dph") "The process whose specific outcome is the progression of a prolactin secreting cell over time, from its formation to the mature structure. A prolactin secreting cell is an acidophilic cell of the anterior pituitary that produces prolactin.") +AnnotationAssertion( "epsilon-acidophil development") +AnnotationAssertion( "lactotrope development") +AnnotationAssertion( "lactotroph development") +AnnotationAssertion( "lactotropic cell development") +AnnotationAssertion( "mammotrope development") +AnnotationAssertion( "mammotroph development") +AnnotationAssertion( "mammotrophic cell development") +AnnotationAssertion( "mammotropic cell development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060132") +AnnotationAssertion(rdfs:label "prolactin secreting cell development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (somatotropin secreting cell development) + +AnnotationAssertion(Annotation( "GOC:dph") "The process whose specific outcome is the progression of a somatotropin secreting cell over time, from its formation to the mature structure. A somatotropin secreting cell is an acidophilic cell of the anterior pituitary that produces growth hormone, somatotropin.") +AnnotationAssertion( "growth hormone secreting cell development") +AnnotationAssertion( "somatotrophin secreting cell development") +AnnotationAssertion( "somatotropic cell development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "somatotrope development") +AnnotationAssertion( "somatotroph development") +AnnotationAssertion( "somatrophic cell development") +AnnotationAssertion( "GO:0060133") +AnnotationAssertion(rdfs:label "somatotropin secreting cell development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (maternal process involved in female pregnancy) + +AnnotationAssertion(Annotation( "GOC:dph") "A reproductive process occurring in the mother that allows an embryo or fetus to develop within it.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060135") +AnnotationAssertion(rdfs:label "maternal process involved in female pregnancy") +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (embryonic process involved in female pregnancy) + +AnnotationAssertion(Annotation( "GOC:dph") "A reproductive process occurring in the embryo or fetus that allows the embryo or fetus to develop within the mother.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060136") +AnnotationAssertion(rdfs:label "embryonic process involved in female pregnancy") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (regulation of syncytium formation by plasma membrane fusion) + +AnnotationAssertion(Annotation( "GOC:dph") "Any process that modulates the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060142") +AnnotationAssertion(rdfs:label "regulation of syncytium formation by plasma membrane fusion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (positive regulation of syncytium formation by plasma membrane fusion) + +AnnotationAssertion(Annotation( "GOC:dph") "Any process that increases the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060143") +AnnotationAssertion(rdfs:label "positive regulation of syncytium formation by plasma membrane fusion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + # Class: (milk ejection reflex) AnnotationAssertion(Annotation( "GOC:cjm") Annotation( "GOC:dph") Annotation( "GOC:mr") Annotation( "GOC:st") "A reflex that occurs in response to suckling, beginning with a nerve impulse from a receptor in the mammary gland and ending with the ejection of milk from the gland. Signaling never reaches a level of consciousness.") @@ -39910,6 +96808,100 @@ SubClassOf( ObjectSomeValuesFrom( ObjectSomeValuesFrom( )) SubClassOf( ObjectAllValuesFrom( )) +# Class: (urinary bladder development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:ln") Annotation( "GOC:mr") Annotation( "PMID:11768524") Annotation( "PMID:18276178") Annotation( "PMID:538956") "The process whose specific outcome is the progression of the urinary bladder over time, from its formation to the mature structure. The urinary bladder is an elastic, muscular sac situated in the anterior part of the pelvic cavity in which urine collects before excretion.") +AnnotationAssertion( ) +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060157") +AnnotationAssertion(rdfs:label "urinary bladder development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses( ObjectSomeValuesFrom( )) + +# Class: (olfactory pit development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "ISBN:0124020607") "The biological process whose specific outcome is the progression of the olfactory pit from an initial condition to its mature state. This process begins with the formation of the olfactory pit, which is an indentation of the olfactory placode, and ends when the pits hollows out to form the nasopharynx.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/22589"^^xsd:anyURI) +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060166") +AnnotationAssertion(rdfs:label "olfactory pit development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (regulation of adenosine receptor signaling pathway) + +AnnotationAssertion(Annotation( "GOC:dph") "Any process that modulates the frequency, rate or extent of the adenosine receptor signaling pathway. The adenosine receptor pathway is the series of molecular signals generated as a consequence of an adenosine receptor binding to one of its physiological ligands.") +AnnotationAssertion(Annotation( "GOC:mah") "regulation of adenosine receptor signalling pathway") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060167") +AnnotationAssertion(rdfs:label "regulation of adenosine receptor signaling pathway") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of adenosine receptor signaling pathway) + +AnnotationAssertion(Annotation( "GOC:dph") "Any process that activates or increases the frequency, rate or extent of the adenosine receptor signaling pathway. The adenosine receptor pathway is the series of molecular signals generated as a consequence of an adenosine receptor binding to one of its physiological ligands.") +AnnotationAssertion(Annotation( "GOC:mah") "positive regulation of adenosine receptor signalling pathway") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060168") +AnnotationAssertion(rdfs:label "positive regulation of adenosine receptor signaling pathway") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of adenosine receptor signaling pathway) + +AnnotationAssertion(Annotation( "GOC:dph") "Any process that stops, prevents, or reduces the frequency, rate or extent of the adenosine receptor signaling pathway. The adenosine receptor pathway is the series of molecular signals generated as a consequence of an adenosine receptor binding to one of its physiological ligands.") +AnnotationAssertion(Annotation( "GOC:mah") "negative regulation of adenosine receptor signalling pathway") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060169") +AnnotationAssertion(rdfs:label "negative regulation of adenosine receptor signaling pathway") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (ciliary membrane) + +AnnotationAssertion(Annotation( "GOC:cilia") Annotation( "GOC:dph") Annotation( "GOC:rph") "The portion of the plasma membrane surrounding a cilium.") +AnnotationAssertion( "GO:0020017") +AnnotationAssertion( "cilial membrane") +AnnotationAssertion( "cilium membrane") +AnnotationAssertion( "flagellar membrane") +AnnotationAssertion( "flagellum membrane") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0060170") +AnnotationAssertion(rdfs:comment "Note that cilia and eukaryotic flagella are deemed to be equivalent.") +AnnotationAssertion(rdfs:label "ciliary membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (limb development) + +AnnotationAssertion(Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "PMID:11487378") "The process whose specific outcome is the progression of a limb over time, from its formation to the mature structure. A limb is an appendage of an animal used for locomotion or grasping. Examples include legs, arms or some types of fin.") +AnnotationAssertion( "Wikipedia:Limb_development") +AnnotationAssertion( "paired limb/fin development") +AnnotationAssertion(Annotation( "GOC:dph") "limb bud development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060173") +AnnotationAssertion(rdfs:label "limb development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (limb bud formation) + +AnnotationAssertion(Annotation( "GOC:dgh") Annotation( "GOC:dph") "The process pertaining to the initial formation of a limb bud from unspecified parts. This process begins with the formation of a local condensation of mesenchyme cells within the prospective limb field, and ends when a limb bud is recognizable.") +AnnotationAssertion( "limb formation") +AnnotationAssertion( "limbbud formation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060174") +AnnotationAssertion(rdfs:label "limb bud formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (estrous cycle phase) AnnotationAssertion(Annotation( "GOC:dph") "The progression of physiological phases, occurring in the endometrium during the estrous cycle that recur at regular intervals during the reproductive years. The estrous cycle is an ovulation cycle where the endometrium is resorbed if pregnancy does not occur.") @@ -39931,6 +96923,106 @@ AnnotationAssertion(rdfs:comment "No AnnotationAssertion(rdfs:label "estrus") SubClassOf( ) +# Class: (endocardium formation) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:dph") Annotation( "PMID:17722983") "Formation of the endocardium of the heart. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060214") +AnnotationAssertion(rdfs:label "endocardium formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (hematopoietic stem cell differentiation) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:bf") Annotation( "GOC:dph") Annotation( "GOC:rl") Annotation( "PMID:15378083") "The process in which a relatively unspecialized cell acquires specialized features of a hematopoietic stem cell. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells.") +AnnotationAssertion( "haematopoietic stem cell differentiation") +AnnotationAssertion( "haemopoietic stem cell differentiation") +AnnotationAssertion( "hemopoietic stem cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060218") +AnnotationAssertion(rdfs:label "hematopoietic stem cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (camera-type eye photoreceptor cell differentiation) + +AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "The process in which a relatively unspecialized cell acquires the specialized features of a photoreceptor cell in a camera-type eye.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060219") +AnnotationAssertion(rdfs:label "camera-type eye photoreceptor cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (retinal rod cell differentiation) + +AnnotationAssertion(Annotation( "GOC:dph") "The process in which a relatively unspecialized cell acquires the specialized features of a retinal rod cell.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060221") +AnnotationAssertion(rdfs:label "retinal rod cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (mesenchymal to epithelial transition) + +AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "A transition where a mesenchymal cell establishes apical/basolateral polarity, forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell.") +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:rl") "epithelial cell differentiation from mesenchymal cell") +AnnotationAssertion(Annotation( "GOC:dph") "mesenchymal-epithelial transition") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060231") +AnnotationAssertion(rdfs:label "mesenchymal to epithelial transition") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (anatomical structure homeostasis) + +AnnotationAssertion(Annotation( "GOC:dph") "A homeostatic process involved in the maintenance of an internal steady state within a defined anatomical structure of an organism, including control of cellular proliferation and death and control of metabolic function. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.") +AnnotationAssertion(Annotation( "GOC:dph") "anatomical structure maintenance") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060249") +AnnotationAssertion(rdfs:label "anatomical structure homeostasis") +SubClassOf( ) + +# Class: (regulation of glial cell proliferation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the frequency, rate or extent of glial cell proliferation.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060251") +AnnotationAssertion(rdfs:label "regulation of glial cell proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of glial cell proliferation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:sl") Annotation( "GOC:tb") "Any process that activates or increases the rate or extent of glial cell proliferation.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060252") +AnnotationAssertion(rdfs:label "positive regulation of glial cell proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (negative regulation of glial cell proliferation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:sl") Annotation( "GOC:tb") "Any process that stops or decreases the rate or extent of glial cell proliferation.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060253") +AnnotationAssertion(rdfs:label "negative regulation of glial cell proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of macromolecule metabolic process) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060255") +AnnotationAssertion(rdfs:label "regulation of macromolecule metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + # Class: (regulation of feeding behavior) AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the rate, frequency or extent of the behavior associated with the intake of food.") @@ -39938,14 +97030,341 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:0060259") AnnotationAssertion(rdfs:label "regulation of feeding behavior") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (cilium assembly) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:cilia") Annotation( "GOC:dph") Annotation( "GOC:kmv") Annotation( "GOC:pr") Annotation( "GOC:vw") Annotation( "ISBN:0198506732") Annotation( "PMID:13978319") Annotation( "PMID:27350441") Annotation( "Reactome:R-HSA-5617833.2") "The assembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole.") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( "GO:0042384") +AnnotationAssertion( "Reactome:R-HSA-5617833.2") +AnnotationAssertion( "ciliogenesis") +AnnotationAssertion( "cilium formation") +AnnotationAssertion( "microtubule-based flagellum assembly") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:mah") "cilium biogenesis") +AnnotationAssertion( "cilium morphogenesis") +AnnotationAssertion(Annotation( "GOC:dph") "cilium organization") +AnnotationAssertion( "GO:0060271") +AnnotationAssertion(rdfs:comment "Note that we deem cilium and microtubule-based flagellum to be equivalent.") +AnnotationAssertion(rdfs:label "cilium assembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) +SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) +SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) +SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) +SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) +SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) +SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) +SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) +SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) +SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) +SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectAllValuesFrom( )) +DisjointClasses( ObjectSomeValuesFrom( )) +DisjointClasses( ObjectSomeValuesFrom( )) +DisjointClasses( ObjectSomeValuesFrom( )) +DisjointClasses( ObjectSomeValuesFrom( )) +DisjointClasses( ObjectSomeValuesFrom( )) +DisjointClasses( ObjectSomeValuesFrom( )) + +# Class: (regulation of oocyte development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") Annotation( "PMID:2394318") "Any process that modulates the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060281") +AnnotationAssertion(rdfs:label "regulation of oocyte development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (positive regulation of oocyte development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that increases the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060282") +AnnotationAssertion(rdfs:label "positive regulation of oocyte development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of oocyte development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that decreases the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060283") +AnnotationAssertion(rdfs:label "negative regulation of oocyte development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of cell development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060284") +AnnotationAssertion(rdfs:label "regulation of cell development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (cilium-dependent cell motility) + +AnnotationAssertion(Annotation( "GOC:cilia") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "GOC:krc") Annotation( "GOC:mlg") Annotation( "GOC:mtg_cambridge_2013") "Cell motility due to the motion of one or more eukaryotic cilia. A eukaryotic cilium is a specialized organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole.") +AnnotationAssertion( "GO:0071974") +AnnotationAssertion( "cilium cell motility") +AnnotationAssertion( "microtubule-based flagellar cell motility") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "ciliary cell motility") +AnnotationAssertion( "GO:0060285") +AnnotationAssertion(rdfs:comment "Note that we deem eukaryotic cilia and microtubule-based flagella to be equivalent.") +AnnotationAssertion(rdfs:label "cilium-dependent cell motility") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cilium movement involved in cell motility) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:tb") "Movement of cilia mediated by motor proteins that contributes to the movement of a cell.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060294") +AnnotationAssertion(rdfs:label "cilium movement involved in cell motility") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (regulation of cilium movement involved in cell motility) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the rate frequency or extent of cilium movement involved in ciliary motility.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060295") +AnnotationAssertion(rdfs:label "regulation of cilium movement involved in cell motility") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (regulation of sarcomere organization) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the rate, frequency or extent of myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs.") +AnnotationAssertion(Annotation( "GOC:mah") "regulation of sarcomere organisation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060297") +AnnotationAssertion(rdfs:label "regulation of sarcomere organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (positive regulation of sarcomere organization) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that increases the rate, frequency or extent of myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs.") +AnnotationAssertion(Annotation( "GOC:mah") "positive regulation of sarcomere organisation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060298") +AnnotationAssertion(rdfs:label "positive regulation of sarcomere organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (negative regulation of sarcomere organization) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that decreases the rate, frequency or extent of myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs.") +AnnotationAssertion(Annotation( "GOC:mah") "negative regulation of sarcomere organisation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060299") +AnnotationAssertion(rdfs:label "negative regulation of sarcomere organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (head development) + +AnnotationAssertion(Annotation( "GOC:dph") "The biological process whose specific outcome is the progression of a head from an initial condition to its mature state. The head is the anterior-most division of the body.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060322") +AnnotationAssertion(rdfs:label "head development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (head morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") "The process in which the anatomical structures of the head are generated and organized. The head is the anterior-most division of the body.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060323") +AnnotationAssertion(rdfs:label "head morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (face development) + +AnnotationAssertion(Annotation( "GOC:dph") "The biological process whose specific outcome is the progression of a face from an initial condition to its mature state. The face is the ventral division of the head.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060324") +AnnotationAssertion(rdfs:label "face development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (face morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") "The process in which the anatomical structures of the face are generated and organized. The face is the ventral division of the head.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060325") +AnnotationAssertion(rdfs:label "face morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cell chemotaxis) + +AnnotationAssertion(Annotation( "GOC:dph") "The directed movement of a motile cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060326") +AnnotationAssertion(rdfs:label "cell chemotaxis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (regulation of cellular localization) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the frequency, rate or extent of a process in which a cell, a substance, or a cellular entity is transported to, or maintained in a specific location within or in the membrane of a cell.") +AnnotationAssertion(Annotation( "GOC:mah") "regulation of cellular localisation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060341") +AnnotationAssertion(rdfs:label "regulation of cellular localization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (trabecula formation) + +AnnotationAssertion(Annotation( "GOC:dph") "The process of creating a trabecula in an organ. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue.") +AnnotationAssertion(Annotation( "GOC:dph") "trabeculation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") "trabecula biogenesis") +AnnotationAssertion( "GO:0060343") +AnnotationAssertion(rdfs:label "trabecula formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (liver trabecula formation) + +AnnotationAssertion(Annotation( "GOC:dph") "The process of creating a trabecula in the liver. A trabecula is a tissue element in the form of a small beam, strut or rod.") +AnnotationAssertion(Annotation( "GOC:dph") "liver trabeculation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "liver trabecula biogenesis") +AnnotationAssertion( "GO:0060344") +AnnotationAssertion(rdfs:label "liver trabecula formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (spleen trabecula formation) + +AnnotationAssertion(Annotation( "GOC:dph") "The process of creating a trabecula in the spleen. A trabecula is a tissue element in the form of a small beam, strut or rod.") +AnnotationAssertion(Annotation( "GOC:dph") "spleen trabeculation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") "spleen trabecula biogenesis") +AnnotationAssertion( "GO:0060345") +AnnotationAssertion(rdfs:label "spleen trabecula formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (bone trabecula formation) + +AnnotationAssertion(Annotation( "GOC:dph") "The process of creating a trabecula in the bone. A trabecula is a tissue element in the form of a small beam, strut or rod.") +AnnotationAssertion(Annotation( "GOC:dph") "bone trabeculation") +AnnotationAssertion(Annotation( "GOC:dph") "skeletal trabecula formation") +AnnotationAssertion(Annotation( "GOC:dph") "skeletal trabeculation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") "bone trabecula biogenesis") +AnnotationAssertion(Annotation( "GOC:dph") "skeletal trabecula biogenesis") +AnnotationAssertion( "GO:0060346") +AnnotationAssertion(rdfs:label "bone trabecula formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (heart trabecula formation) + +AnnotationAssertion(Annotation( "GOC:dph") "The process of creating a trabecula in the heart. A trabecula is a tissue element in the form of a small beam, strut or rod.") +AnnotationAssertion(Annotation( "GOC:dph") "cardiac trabecula formation") +AnnotationAssertion(Annotation( "GOC:dph") "cardiac trabeculation") +AnnotationAssertion(Annotation( "GOC:dph") "heart trabeculation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") "heart trabecula biogenesis") +AnnotationAssertion( "GO:0060347") +AnnotationAssertion(rdfs:label "heart trabecula formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (bone development) + +AnnotationAssertion(Annotation( "GOC:dph") "The process whose specific outcome is the progression of bone over time, from its formation to the mature structure. Bone is the hard skeletal connective tissue consisting of both mineral and cellular components.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060348") +AnnotationAssertion(rdfs:label "bone development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (bone morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") "The process in which bones are generated and organized.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060349") +AnnotationAssertion(rdfs:label "bone morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (endochondral bone morphogenesis) AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:11680679") "The process in which bones are generated and organized as a result of the conversion of initial cartilaginous anlage into bone.") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0060350") AnnotationAssertion(rdfs:label "endochondral bone morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (cartilage development involved in endochondral bone morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") "The process whose specific outcome is the progression of the cartilage that will provide a scaffold for mineralization of endochondral bones.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060351") +AnnotationAssertion(rdfs:label "cartilage development involved in endochondral bone morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (response to ammonium ion) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000071") Annotation( "PMID:23509267") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ammonium stimulus.") +AnnotationAssertion( "GO:1903717") +AnnotationAssertion( "response to ammonia") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060359") +AnnotationAssertion(rdfs:label "response to ammonium ion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (flight) @@ -39955,6 +97374,263 @@ AnnotationAssertion( "flight") SubClassOf( ) +# Class: (cranial suture morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:pr") Annotation( "GOC:sl") "The process in which any suture between cranial bones is generated and organized.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060363") +AnnotationAssertion(rdfs:label "cranial suture morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (frontal suture morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:sl") "The process in which the frontal suture is generated and organized.") +AnnotationAssertion( "interfrontal suture morphogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060364") +AnnotationAssertion(rdfs:label "frontal suture morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (coronal suture morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:sl") "The process in which the coronal suture is generated and organized.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060365") +AnnotationAssertion(rdfs:label "coronal suture morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (lambdoid suture morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:sl") "The process in which the lambdoid suture is generated and organized.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060366") +AnnotationAssertion(rdfs:label "lambdoid suture morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (sagittal suture morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:sl") "The process in which the sagittal suture is generated and organized.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060367") +AnnotationAssertion(rdfs:label "sagittal suture morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (cardiac muscle cell myoblast differentiation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "The process in which a relatively unspecialized cell acquires specialized features of a cardiac myoblast. A cardiac myoblast is a precursor cell that has been committed to a cardiac muscle cell fate but retains the ability to divide and proliferate throughout life.") +AnnotationAssertion(Annotation( "GOC:mtg_heart") "myocardial precursor cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "cardiac myoblast differentiation") +AnnotationAssertion( "GO:0060379") +AnnotationAssertion(rdfs:label "cardiac muscle cell myoblast differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (axonemal microtubule depolymerization) + +AnnotationAssertion(Annotation( "GOC:cilia") Annotation( "GOC:dph") Annotation( "GOC:krc") Annotation( "GOC:tb") "The removal of tubulin heterodimers from one or both ends of an axonemal microtubule. An axonemal microtubule is a microtubule in the axoneme of a cilium or flagellum; an axoneme contains nine modified doublet microtubules surrounding a pair of single microtubules.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060404") +AnnotationAssertion(rdfs:label "axonemal microtubule depolymerization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of penile erection) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the rate, frequency or extent of penile erection. Penile erection is the hardening, enlarging and rising of the penis which often occurs in the sexually aroused male and enables sexual intercourse. Achieved by increased inflow of blood into the vessels of erectile tissue, and decreased outflow.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060405") +AnnotationAssertion(rdfs:label "regulation of penile erection") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of penile erection) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that increases the rate, frequency or extent of penile erection. Penile erection is the hardening, enlarging and rising of the penis which often occurs in the sexually aroused male and enables sexual intercourse. Achieved by increased inflow of blood into the vessels of erectile tissue, and decreased outflow.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060406") +AnnotationAssertion(rdfs:label "positive regulation of penile erection") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of penile erection) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that stops, prevents, or reduces the rate, frequency or extent of penile erection. Penile erection is the hardening, enlarging and rising of the penis which often occurs in the sexually aroused male and enables sexual intercourse. Achieved by increased inflow of blood into the vessels of erectile tissue, and decreased outflow.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060407") +AnnotationAssertion(rdfs:label "negative regulation of penile erection") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of acetylcholine metabolic process) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the rate, frequency or extent of the chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060408") +AnnotationAssertion(rdfs:label "regulation of acetylcholine metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of acetylcholine metabolic process) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that increases the rate, frequency or extent of the chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060409") +AnnotationAssertion(rdfs:label "positive regulation of acetylcholine metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (negative regulation of acetylcholine metabolic process) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that decreases the rate, frequency or extent of the chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060410") +AnnotationAssertion(rdfs:label "negative regulation of acetylcholine metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (cardiac septum morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_heart") "The process in which the anatomical structure of a cardiac septum is generated and organized. A cardiac septum is a partition that separates parts of the heart.") +AnnotationAssertion( "GO:0003280") +AnnotationAssertion( "heart septum morphogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060411") +AnnotationAssertion(rdfs:label "cardiac septum morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (ventricular septum morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") "The developmental process in which a ventricular septum is generated and organized. A ventricular septum is an anatomical structure that separates the lower chambers (ventricles) of the heart from one another.") +AnnotationAssertion(Annotation( "GOC:dph") "interventricular septum morphogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060412") +AnnotationAssertion(rdfs:label "ventricular septum morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (atrial septum morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_heart") "The developmental process in which atrial septum is generated and organized. The atrial septum separates the upper chambers (the atria) of the heart from one another.") +AnnotationAssertion( "GO:0003287") +AnnotationAssertion(Annotation( "GOC:dph") "interatrial septum morphogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060413") +AnnotationAssertion(rdfs:label "atrial septum morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (aorta smooth muscle tissue morphogenesis) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:dgh") Annotation( "GOC:dph") Annotation( "Wikipedia:Aorta") "The process in which the structure of the smooth muscle tissue surrounding the aorta is generated and organized. An aorta is an artery that carries blood from the heart to other parts of the body.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060414") +AnnotationAssertion(rdfs:label "aorta smooth muscle tissue morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (muscle tissue morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") "The process in which the anatomical structures of muscle tissue are generated and organized. Muscle tissue consists of a set of cells that are part of an organ and carry out a contractive function.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060415") +AnnotationAssertion(rdfs:label "muscle tissue morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (heart growth) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "The increase in size or mass of the heart.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060419") +AnnotationAssertion(rdfs:label "heart growth") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (regulation of heart growth) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060420") +AnnotationAssertion(rdfs:label "regulation of heart growth") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (positive regulation of heart growth) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that increases the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060421") +AnnotationAssertion(rdfs:label "positive regulation of heart growth") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (lung morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") "The process in which the anatomical structures of the lung are generated and organized.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060425") +AnnotationAssertion(rdfs:label "lung morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (lung vasculature development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_lung") "The biological process whose specific outcome is the progression of a lung vasculature from an initial condition to its mature state. This process begins with the formation of the lung vasculature and ends with the mature structure. The lung vasculature is composed of the tubule structures that carry blood or lymph in the lungs.") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_lung") "pulmonary vasculature development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060426") +AnnotationAssertion(rdfs:label "lung vasculature development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (lung connective tissue development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_lung") "The biological process whose specific outcome is the progression of lung connective tissue from an initial condition to its mature state. This process begins with the formation of lung connective tissue and ends with the mature structure. The lung connective tissue is a material made up of fibers forming a framework and support structure for the lungs.") +AnnotationAssertion( "pulmonary connective tissue development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060427") +AnnotationAssertion(rdfs:label "lung connective tissue development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (lung epithelium development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_lung") "The biological process whose specific outcome is the progression of the lung epithelium from an initial condition to its mature state. This process begins with the formation of lung epithelium and ends with the mature structure. The lung epithelium is the specialized epithelium that lines the inside of the lung.") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_lung") "pulmonary epithelium development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060428") +AnnotationAssertion(rdfs:label "lung epithelium development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (epithelium development) AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_lung") "The process whose specific outcome is the progression of an epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure.") @@ -39962,8 +97638,751 @@ AnnotationAssertion( "GO:0060429") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "epithelium development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (lung saccule development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_lung") "The biological process whose specific outcome is the progression of a lung saccule from an initial condition to its mature state. The lung saccule is the primitive gas exchange portion of the lung composed of type I and type II cells.") +AnnotationAssertion(Annotation( "GOC:dph") "lung saccular development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060430") +AnnotationAssertion(rdfs:label "lung saccule development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (primary lung bud formation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_lung") "The morphogenetic process in which the foregut region specified to become the lung forms the initial left and right buds.") +AnnotationAssertion(Annotation( "GOC:dph") "lung formation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060431") +AnnotationAssertion(rdfs:label "primary lung bud formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (bronchus development) + +AnnotationAssertion(Annotation( "GOC:dph") "The biological process whose specific outcome is the progression of a bronchus from an initial condition to its mature state. This process begins with the formation of the bronchus and ends with the mature structure. The bronchus is the portion of the airway that connects to the lungs.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060433") +AnnotationAssertion(rdfs:label "bronchus development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (bronchus morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") "The process in which the bronchus is generated and organized. The bronchus is the portion of the airway that connects to the lungs.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060434") +AnnotationAssertion(rdfs:label "bronchus morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (bronchiole development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_lung") "The biological process whose specific outcome is the progression of a bronchiole from an initial condition to its mature state. This process begins with the formation of the bronchiole and ends with the mature structure. A bronchiole is the first airway branch that no longer contains cartilage; it is a branch of the bronchi.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060435") +AnnotationAssertion(rdfs:label "bronchiole development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (bronchiole morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") "The process in which a bronchiole is generated and organized. A bronchiole is the first airway branch that no longer contains cartilage; it is a branch of the bronchi.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060436") +AnnotationAssertion(rdfs:label "bronchiole morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (lung growth) + +AnnotationAssertion(Annotation( "GOC:dph") "The increase in size or mass of a lung. In all air-breathing vertebrates the lungs are developed from the ventral wall of the oesophagus as a pouch which divides into two sacs. In amphibians and many reptiles the lungs retain very nearly this primitive sac-like character, but in the higher forms the connection with the esophagus becomes elongated into the windpipe and the inner walls of the sacs become more and more divided, until, in the mammals, the air spaces become minutely divided into tubes ending in small air cells, in the walls of which the blood circulates in a fine network of capillaries. In mammals the lungs are more or less divided into lobes, and each lung occupies a separate cavity in the thorax.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060437") +AnnotationAssertion(rdfs:label "lung growth") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (trachea development) + +AnnotationAssertion(Annotation( "GOC:dph") "The process whose specific outcome is the progression of a trachea over time, from its formation to the mature structure. The trachea is the portion of the airway that attaches to the bronchi as it branches.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060438") +AnnotationAssertion(rdfs:label "trachea development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (trachea morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") "The process in which a trachea is generated and organized. The trachea is the portion of the airway that attaches to the bronchi as it branches.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060439") +AnnotationAssertion(rdfs:label "trachea morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (trachea formation) + +AnnotationAssertion(Annotation( "GOC:dph") "The process pertaining to the initial formation of a trachea from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the trachea is recognizable. The trachea is the portion of the airway that attaches to the bronchi as it branches.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060440") +AnnotationAssertion(rdfs:label "trachea formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (epithelial tube branching involved in lung morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_lung") "The process in which a highly ordered sequence of patterning events generates the branched epithelial tubes of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units.") +AnnotationAssertion(Annotation( "GOC:dph") "lung branching morphogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060441") +AnnotationAssertion(rdfs:label "epithelial tube branching involved in lung morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (branching involved in prostate gland morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") "The process in which the branching structure of the prostate gland is generated and organized. A branch is a division or offshoot from a main stem.") +AnnotationAssertion(Annotation( "GOC:dph") "prostate gland branching morphogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") "prostate branching") +AnnotationAssertion( "GO:0060442") +AnnotationAssertion(rdfs:label "branching involved in prostate gland morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (mammary gland morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") "The process in which anatomical structures of the mammary gland are generated and organized. Morphogenesis refers to the creation of shape. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060443") +AnnotationAssertion(rdfs:label "mammary gland morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (branching involved in mammary gland duct morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") "The process in which the branching structure of the mammary gland duct is generated and organized. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk.") +AnnotationAssertion(Annotation( "GOC:dph") "mammary gland branching morphogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060444") +AnnotationAssertion(rdfs:label "branching involved in mammary gland duct morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (branching involved in salivary gland morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") "The process in which the branching structure of the salivary gland is generated and organized.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060445") +AnnotationAssertion(rdfs:label "branching involved in salivary gland morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (branching involved in open tracheal system development) + +AnnotationAssertion(Annotation( "GOC:dph") "The process in which the anatomical structures of branches in the open tracheal system are generated and organized.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060446") +AnnotationAssertion(rdfs:label "branching involved in open tracheal system development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of hindgut contraction) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that increases the frequency, rate or extent of muscle contraction of the hindgut, the posterior part of the alimentary canal, including the rectum, and the large intestine.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060450") +AnnotationAssertion(rdfs:label "positive regulation of hindgut contraction") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of hindgut contraction) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that decreases the frequency, rate or extent of muscle contraction of the hindgut, the posterior part of the alimentary canal, including the rectum, and the large intestine.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060451") +AnnotationAssertion(rdfs:label "negative regulation of hindgut contraction") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of cardiac muscle contraction) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that increases the frequency, rate or extent of cardiac muscle contraction.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060452") +AnnotationAssertion(rdfs:label "positive regulation of cardiac muscle contraction") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of gastric acid secretion) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the rate frequency or extent of gastric secretion. Gastric secretion is the regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060453") +AnnotationAssertion(rdfs:label "regulation of gastric acid secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of gastric acid secretion) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that increases the rate frequency or extent of gastric secretion. Gastric secretion is the regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060454") +AnnotationAssertion(rdfs:label "positive regulation of gastric acid secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of gastric acid secretion) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that decreases the rate frequency or extent of gastric secretion. Gastric secretion is the regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060455") +AnnotationAssertion(rdfs:label "negative regulation of gastric acid secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of digestive system process) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that increases the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060456") +AnnotationAssertion(rdfs:label "positive regulation of digestive system process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of digestive system process) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that decreases the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060457") +AnnotationAssertion(rdfs:label "negative regulation of digestive system process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (right lung development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_lung") "The biological process whose specific outcome is the progression of a right lung from an initial condition to its mature state. This process begins with the formation of the right lung and ends with the mature structure. The right lung is the lung which is on the right side of the anterior posterior axis looking from a dorsal to ventral aspect.") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_lung") "right pulmonary development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060458") +AnnotationAssertion(rdfs:label "right lung development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (left lung development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_lung") "The biological process whose specific outcome is the progression of a left lung from an initial condition to its mature state. This process begins with the formation of the left lung and ends with the mature structure. The left lung is the lung which is on the left side of the anterior posterior axis looking from a dorsal to ventral aspect.") +AnnotationAssertion(Annotation( "GOC:dph") "left pulmonary development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060459") +AnnotationAssertion(rdfs:label "left lung development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (left lung morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") "The process in which anatomical structures of the left lung are generated and organized.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060460") +AnnotationAssertion(rdfs:label "left lung morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (right lung morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_lung") "The process in which anatomical structures of the right lung are generated and organized.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060461") +AnnotationAssertion(rdfs:label "right lung morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (lung lobe development) + +AnnotationAssertion(Annotation( "GOC:dph") "The biological process whose specific outcome is the progression of a lung lobe from an initial condition to its mature state. This process begins with the formation of a lung lobe by branching morphogenesis and ends with the mature structure. A lung lobe is one of the rounded projections that compose the lung.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060462") +AnnotationAssertion(rdfs:label "lung lobe development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (lung lobe morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") "The process in which the anatomical structures of a lung lobe are generated and organized. A lung lobe is a projection that extends from the lung.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060463") +AnnotationAssertion(rdfs:label "lung lobe morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (lung lobe formation) + +AnnotationAssertion(Annotation( "GOC:dph") "The developmental process pertaining to the initial formation of a lung lobe from unspecified parts. This process begins with the specific processes that contribute to the appearance of the lobe and ends when the structural rudiment is recognizable. A lung lobe is a projection that extends from the lung.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060464") +AnnotationAssertion(rdfs:label "lung lobe formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (pharynx development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:rk") "The biological process whose specific outcome is the progression of a pharynx from an initial condition to its mature state. The pharynx is the part of the digestive system immediately posterior to the mouth.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "pharyngeal development") +AnnotationAssertion( "GO:0060465") +AnnotationAssertion(rdfs:label "pharynx development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (negative regulation of fertilization) + +AnnotationAssertion(Annotation( "GOC:dph") "Any process that decreases the rate, frequency or extent of fertilization. Fertilization is the union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy).") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060467") +AnnotationAssertion(rdfs:label "negative regulation of fertilization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (prevention of polyspermy) + +AnnotationAssertion(Annotation( "GOC:dph") "The negative regulation of fertilization process that takes place as part of egg activation, ensuring that only a single sperm fertilizes the egg.") +AnnotationAssertion(Annotation( "GOC:dph") "negative regulation of fertilization involved in egg activation") +AnnotationAssertion(Annotation( "GOC:dph") "polyspermy block") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060468") +AnnotationAssertion(rdfs:label "prevention of polyspermy") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of flagellated sperm motility involved in capacitation) + +AnnotationAssertion(Annotation( "GOC:cilia") Annotation( "GOC:dph") Annotation( "GOC:krc") "The process in which the controlled movement of a flagellated sperm cell is initiated as part of the process required for flagellated sperm to reach fertilization competence.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "positive regulation of sperm motility involved in capacitation") +AnnotationAssertion( "GO:0060474") +AnnotationAssertion(rdfs:label "positive regulation of flagellated sperm motility involved in capacitation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (lung cell differentiation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_lung") "The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features of a mature cell found in the lung. Differentiation includes the processes involved in commitment of a cell to a specific fate.") +AnnotationAssertion(Annotation( "GOC:dph") "pulmonary cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060479") +AnnotationAssertion(rdfs:label "lung cell differentiation") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (lung goblet cell differentiation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_lung") "The process in which a relatively unspecialized cell acquires specialized features of a lung goblet cell. A goblet cell is a cell of the epithelial lining that produces and secretes mucins.") +AnnotationAssertion( "pulmonary goblet cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060480") +AnnotationAssertion(rdfs:label "lung goblet cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (lobar bronchus epithelium development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_lung") "The biological process whose specific outcome is the progression of a lobar bronchus epithelium from an initial condition to its mature state. This process begins with the formation of the lobar bronchus epithelium and ends with the mature structure. The lobar bronchus epithelium is the tissue made up of epithelial cells that lines the inside of the lobar bronchus.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060481") +AnnotationAssertion(rdfs:label "lobar bronchus epithelium development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (lobar bronchus development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_lung") "The biological process whose specific outcome is the progression of a lobar bronchus from an initial condition to its mature state. This process begins with the formation of the lobar bronchus and ends with the mature structure. The lobar bronchus is the major airway within the respiratory tree that starts by division of the principal bronchi on both sides and ends at the point of its own subdivision into tertiary or segmental bronchi.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060482") +AnnotationAssertion(rdfs:label "lobar bronchus development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (lobar bronchus mesenchyme development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_lung") "The biological process whose specific outcome is the progression of a lobar bronchus mesenchyme from an initial condition to its mature state. This process begins with the formation of the lobar bronchus mesenchyme and ends with the mature structure. The lobar bronchus mesenchyme is the mass of tissue composed of mesenchymal cells in the lobar bronchus.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060483") +AnnotationAssertion(rdfs:label "lobar bronchus mesenchyme development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (lung-associated mesenchyme development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_lung") "The biological process whose specific outcome is the progression of a lung-associated mesenchyme from an initial condition to its mature state. This process begins with the formation of lung-associated mesenchyme and ends with the mature structure. Lung-associated mesenchyme is the tissue made up of loosely connected mesenchymal cells in the lung.") +AnnotationAssertion(Annotation( "GOC:dph") "lung mesenchyme development") +AnnotationAssertion(Annotation( "GOC:dph") "pulmonary mesenchyme development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060484") +AnnotationAssertion(rdfs:label "lung-associated mesenchyme development") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (mesenchyme development) + +AnnotationAssertion(Annotation( "GOC:dph") "The process whose specific outcome is the progression of a mesenchymal tissue over time, from its formation to the mature structure. A mesenchymal tissue is made up of loosely packed stellate cells.") +AnnotationAssertion(Annotation( "GOC:dph") "mesenchymal development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060485") +AnnotationAssertion(rdfs:label "mesenchyme development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (club cell differentiation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_lung") Annotation( "PMID:28144783") "The process in which a relatively unspecialized cell acquires specialized features of a club cell. A club cell is an unciliated epithelial cell found in the respiratory and terminal bronchioles.") +AnnotationAssertion(Annotation( "PMID:28144783") "Clara cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060486") +AnnotationAssertion(rdfs:label "club cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (lung epithelial cell differentiation) + +AnnotationAssertion(Annotation( "GOC:dph") "The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell that contributes to the epithelium of the lung.") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") "pulmonary epithelial cell differentiation") +AnnotationAssertion( "GO:0060487") +AnnotationAssertion(rdfs:label "lung epithelial cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (lateral sprouting involved in lung morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_lung") "The process in which a branch forms along the side of the lung epithelial tube.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060490") +AnnotationAssertion(rdfs:label "lateral sprouting involved in lung morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of cell projection assembly) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the rate, frequency, or extent of cell projection assembly.") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "regulation of cell projection formation") +AnnotationAssertion( "GO:0060491") +AnnotationAssertion(rdfs:label "regulation of cell projection assembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (cell-cell signaling involved in lung development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_lung") "Any process that mediates the transfer of information from one cell to another and contributes to the progression of the lung, from its initial state to the mature structure.") +AnnotationAssertion(Annotation( "GOC:mah") "cell-cell signalling involved in lung development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060495") +AnnotationAssertion(rdfs:label "cell-cell signaling involved in lung development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of epithelial cell proliferation involved in lung morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") "Any process that increases the rate or frequency of epithelial cell proliferation that results in the lung attaining its shape.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060501") +AnnotationAssertion(rdfs:label "positive regulation of epithelial cell proliferation involved in lung morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (epithelial cell proliferation involved in lung morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") "The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population that contributes to the shaping of the lung.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060502") +AnnotationAssertion(rdfs:label "epithelial cell proliferation involved in lung morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (type I pneumocyte differentiation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_lung") Annotation( "ISBN:0721662544") "The process in which a relatively unspecialized cell acquires specialized features of a type I pneumocyte. A type I pneumocyte is a flattened cell with greatly attenuated cytoplasm and a paucity of organelles.") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "ISBN:0721662544") "membranous pneumocyte differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "ISBN:0721662544") "small alveolar cell differentiation") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "ISBN:0721662544") "squamous alveolar cell differentiation") +AnnotationAssertion( "GO:0060509") +AnnotationAssertion(rdfs:label "type I pneumocyte differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (type II pneumocyte differentiation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_lung") Annotation( "ISBN:0721662544") "The process in which a relatively unspecialized cell acquires specialized features of a type II pneumocyte. A type II pneumocyte is a surfactant secreting cell that contains abundant cytoplasm containing numerous lipid-rich multilamellar bodies.") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "ISBN:0721662544") "great alveolar cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "ISBN:0721662544") "granular pneumocyte differentiation") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "ISBN:0721662544") "large alveolar cell differentiation") +AnnotationAssertion( "GO:0060510") +AnnotationAssertion(rdfs:label "type II pneumocyte differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (prostate gland morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:18977204") "The process in which the anatomical structures of a prostate gland are generated and organized.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060512") +AnnotationAssertion(rdfs:label "prostate gland morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (prostatic bud formation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:18977204") "The morphogenetic process in which a region of the fetal urogenital sinus epithelium is specified to become the prostate, resulting in prostate bud outgrowth.") +AnnotationAssertion(Annotation( "GOC:dph") "primary prostate bud formation") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:11401393") "prostate ductal budding") +AnnotationAssertion(Annotation( "GOC:dph") "prostate gland formation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060513") +AnnotationAssertion(rdfs:label "prostatic bud formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (prostate glandular acinus development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:18977204") "The progression of a glandular acinus of the prostate gland over time, from its initial formation to the mature structure. The glandular acini are the saclike structures of the gland.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060525") +AnnotationAssertion(rdfs:label "prostate glandular acinus development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (prostate glandular acinus morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") "The process in which the prostate glandular acini are generated and organized. The glandular acini are the saclike structures of the gland.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060526") +AnnotationAssertion(rdfs:label "prostate glandular acinus morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (smooth muscle cell differentiation involved in prostate glandular acinus development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:18977204") "The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell of the prostate glandular acinus.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060530") +AnnotationAssertion(rdfs:label "smooth muscle cell differentiation involved in prostate glandular acinus development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (neuroendocrine cell differentiation involved in prostate gland acinus development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:18977204") "The process in which relatively unspecialized cells acquires specialized structural and functions of a neuroendocrine cell of the prostate gland acinus.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060531") +AnnotationAssertion(rdfs:label "neuroendocrine cell differentiation involved in prostate gland acinus development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (bronchus cartilage development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_lung") "The process whose specific outcome is the progression of lung cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-04-10T08:12:06Z") +AnnotationAssertion( "pulmonary cartilage development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060532") +AnnotationAssertion(rdfs:label "bronchus cartilage development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (bronchus cartilage morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") "The process in which the bronchus cartilage is generated and organized. The bronchus cartilage is the connective tissue of the portion of the airway that connects to the lungs.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-04-10T08:47:41Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060533") +AnnotationAssertion(rdfs:label "bronchus cartilage morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (trachea cartilage development) + +AnnotationAssertion(Annotation( "GOC:dph") "The process whose specific outcome is the progression of the tracheal cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-04-10T09:00:18Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060534") +AnnotationAssertion(rdfs:label "trachea cartilage development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (trachea cartilage morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") "The process in which the anatomical structures of cartilage in the trachea are generated and organized.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-04-10T09:07:48Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060535") +AnnotationAssertion(rdfs:label "trachea cartilage morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cartilage morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") "The process in which the anatomical structures of cartilage are generated and organized.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-04-10T09:13:27Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060536") +AnnotationAssertion(rdfs:label "cartilage morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (muscle tissue development) + +AnnotationAssertion(Annotation( "GOC:dph") "The progression of muscle tissue over time, from its initial formation to its mature state. Muscle tissue is a contractile tissue made up of actin and myosin fibers.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-04-10T08:05:37Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060537") +AnnotationAssertion(rdfs:label "muscle tissue development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (skeletal muscle organ development) + +AnnotationAssertion(Annotation( "GOC:dph") "The progression of a skeletal muscle organ over time from its initial formation to its mature state. A skeletal muscle organ includes the skeletal muscle tissue and its associated connective tissue.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-04-10T08:25:12Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060538") +AnnotationAssertion(rdfs:label "skeletal muscle organ development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (diaphragm development) + +AnnotationAssertion(Annotation( "GOC:dph") "The progression of the diaphragm over time from its initial formation to the mature structure. The diaphragm is a skeletal muscle that is responsible for contraction and expansion of the lungs.") +AnnotationAssertion( ) +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-04-10T08:44:56Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060539") +AnnotationAssertion(rdfs:label "diaphragm development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses( ObjectSomeValuesFrom( )) + +# Class: (diaphragm morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") "The process in which the anatomical structures of the diaphragm are generated and organized.") +AnnotationAssertion( ) +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-04-10T08:47:51Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060540") +AnnotationAssertion(rdfs:label "diaphragm morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses( ObjectSomeValuesFrom( )) + +# Class: (respiratory system development) + +AnnotationAssertion(Annotation( "GOC:dph") "The progression of the respiratory system over time from its formation to its mature structure. The respiratory system carries out respiratory gaseous exchange.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-04-10T08:55:42Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060541") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "respiratory system development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (developmental growth involved in morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") "The increase in size or mass of an anatomical structure that contributes to the structure attaining its shape.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-04-28T08:42:53Z") +AnnotationAssertion(Annotation( "GOC:dph") "differential growth") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060560") +AnnotationAssertion(rdfs:label "developmental growth involved in morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (apoptotic process involved in morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_apoptosis") "Any apoptotic process that contributes to the shaping of an anatomical structure.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-04-28T09:17:27Z") +AnnotationAssertion( "apoptosis involved in morphogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "apoptosis involved in development") +AnnotationAssertion(Annotation( "GOC:dph") "morphogenetic apoptosis") +AnnotationAssertion( "GO:0060561") +AnnotationAssertion(rdfs:label "apoptotic process involved in morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + # Class: (epithelial tube morphogenesis) AnnotationAssertion(Annotation( "GOC:dph") "The process in which the anatomical structures of a tube are generated and organized from an epithelium. Epithelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues, with tube shape and organization varying from the single-celled excretory organ in Caenorhabditis elegans to the branching trees of the mammalian kidney and insect tracheal system.") @@ -39972,9 +98391,232 @@ AnnotationAssertion( AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0060562") AnnotationAssertion(rdfs:label "epithelial tube morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) +# Class: (neuroepithelial cell differentiation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "The process in which epiblast cells acquire specialized features of neuroepithelial cells.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-04-29T01:50:05Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060563") +AnnotationAssertion(rdfs:label "neuroepithelial cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of peptide hormone processing) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the rate, frequency or extent of peptide hormone processing. Peptide hormone processing is the generation of a mature peptide hormone by posttranslational processing of a prohormone.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-04-29T03:16:05Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060568") +AnnotationAssertion(rdfs:label "regulation of peptide hormone processing") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of peptide hormone processing) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that increases the rate, frequency or extent of peptide hormone processing. Peptide hormone processing is the generation of a mature peptide hormone by posttranslational processing of a prohormone.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-04-29T03:22:05Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060569") +AnnotationAssertion(rdfs:label "positive regulation of peptide hormone processing") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of peptide hormone processing) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that decreases the rate, frequency or extent of peptide hormone processing. Peptide hormone processing is the generation of a mature peptide hormone by posttranslational processing of a prohormone.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-04-29T03:24:55Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060570") +AnnotationAssertion(rdfs:label "negative regulation of peptide hormone processing") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (morphogenesis of an epithelial fold) + +AnnotationAssertion(Annotation( "GOC:dph") "The morphogenetic process in which an epithelial sheet bends along a linear axis.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-04-30T09:27:17Z") +AnnotationAssertion(Annotation( "GOC:dph") "epithelial folding") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") "folding of an epithelial sheet") +AnnotationAssertion( "GO:0060571") +AnnotationAssertion(rdfs:label "morphogenesis of an epithelial fold") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (morphogenesis of an epithelial bud) + +AnnotationAssertion(Annotation( "GOC:dph") "The morphogenetic process in which a bud forms from an epithelial sheet. A bud is a protrusion that forms form the sheet by localized folding.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-04-30T09:38:35Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060572") +AnnotationAssertion(rdfs:label "morphogenesis of an epithelial bud") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (intestinal epithelial cell maturation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:18824147") "The developmental process, independent of morphogenetic (shape) change, that is required for a columna/cuboidal epithelial cell of the intestine to attain its fully functional state. A columnar/cuboidal epithelial cell of the intestine mature as they migrate from the intestinal crypt to the villus.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-05-06T08:10:41Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060574") +AnnotationAssertion(rdfs:label "intestinal epithelial cell maturation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (intestinal epithelial cell differentiation) + +AnnotationAssertion(Annotation( "GOC:dph") "The process in which a relatively unspecialized cell acquires specialized features of a columnar/cuboidal epithelial cell of the intestine.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-05-06T08:17:56Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060575") +AnnotationAssertion(rdfs:label "intestinal epithelial cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (intestinal epithelial cell development) + +AnnotationAssertion(Annotation( "GOC:dph") "The process whose specific outcome is the progression of a columnar/cuboidal epithelial cell of the intestine over time, from its formation to the mature structure.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-05-06T08:20:24Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060576") +AnnotationAssertion(rdfs:label "intestinal epithelial cell development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (pulmonary vein morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") "The process in which the anatomical structure of the pulmonary venous blood vessels are generated and organized. Pulmonary veins are blood vessels that transport blood from the lungs to the heart.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-05-06T08:44:04Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") "pulmonary venous blood vessel morphogenesis") +AnnotationAssertion( "GO:0060577") +AnnotationAssertion(rdfs:label "pulmonary vein morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (superior vena cava morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") "The process in which the anatomical structure of superior vena cava generated and organized. The superior vena cava is a blood vessel that transports blood from the upper body to the heart.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-05-06T08:47:21Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060578") +AnnotationAssertion(rdfs:label "superior vena cava morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (cell fate commitment involved in pattern specification) + +AnnotationAssertion(Annotation( "GOC:dph") "The commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells within a field of cells that will exhibit a certain pattern of differentiation. Positional information is established through protein signals that emanate from a localized source within a developmental field resulting in specification of a cell type. Those signals are then interpreted in a cell-autonomous manner resulting in the determination of the cell type.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-05-07T12:40:55Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060581") +AnnotationAssertion(rdfs:label "cell fate commitment involved in pattern specification") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (multicellular organismal-level iron ion homeostasis) + +AnnotationAssertion(Annotation( "PMID:31431773") "A chemical homeostatic process involved in the maintenance of a steady state level of iron within extracellular body fluids, such as blood, xylem or phloem, of a multicellular organism. This is distinct from maintenance of cellular homeostasis, which occurs within a cell.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/24554"^^xsd:anyURI) +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-05-08T02:18:21Z") +AnnotationAssertion( "multicellular organismal iron ion homeostasis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060586") +AnnotationAssertion(rdfs:label "multicellular organismal-level iron ion homeostasis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (chondroblast differentiation) + +AnnotationAssertion(Annotation( "GOC:dph") "The process in which a mesenchymal cell, acquires specialized structural and/or functional features of a chondroblast. Differentiation includes the processes involved in commitment of a cell to a chondroblast fate. A chondroblast is a precursor cell to chondrocytes.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-05-11T07:47:36Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") "chondrocyte progenitor cell differentiation") +AnnotationAssertion( "GO:0060591") +AnnotationAssertion(rdfs:label "chondroblast differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (mammary gland formation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:16168142") Annotation( "PMID:17120154") "The process pertaining to the initial formation of the mammary gland from unspecified parts. The process begins with formation of the mammary line and ends when the solid mammary bud invades the primary mammary mesenchyme.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-05-13T08:47:52Z") +AnnotationAssertion(Annotation( "GOC:dph") "mammary line formation") +AnnotationAssertion(Annotation( "GOC:dph") "mammary placode formation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") "mammary bud formation") +AnnotationAssertion(Annotation( "GOC:dph") "mammary sprout formation") +AnnotationAssertion( "GO:0060592") +AnnotationAssertion(rdfs:label "mammary gland formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (mammary placode formation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:16168142") "The developmental process in which the mammary placode forms. The mammary placode is a transient lens shaped structure that will give rise to the mammary bud proper.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-05-13T11:55:20Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060596") +AnnotationAssertion(rdfs:label "mammary placode formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (lateral sprouting involved in mammary gland duct morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:17120154") "The process in which a branch forms along the side of a mammary duct.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-05-13T12:38:06Z") +AnnotationAssertion(Annotation( "GOC:dph") "mammary gland duct secondary branching") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060599") +AnnotationAssertion(rdfs:label "lateral sprouting involved in mammary gland duct morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (lateral sprouting from an epithelium) + +AnnotationAssertion(Annotation( "GOC:dph") "The process in which a branch forms along the side of an epithelium.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-05-14T02:33:01Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060601") +AnnotationAssertion(rdfs:label "lateral sprouting from an epithelium") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (mammary gland duct morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:17120154") "The process in which anatomical structures of the mammary ducts are generated and organized. Mammary ducts are epithelial tubes that transport milk.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-05-15T09:22:25Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060603") +AnnotationAssertion(rdfs:label "mammary gland duct morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (tube closure) AnnotationAssertion(Annotation( "GOC:dph") "Creation of the central hole of a tube in an anatomical structure by sealing the edges of an epithelial fold.") @@ -39985,6 +98627,1657 @@ AnnotationAssertion( "tube closure") SubClassOf( ) +# Class: (mesenchymal cell differentiation involved in mammary gland development) + +AnnotationAssertion(Annotation( "GOC:dph") "The process in which a relatively unspecialized cell acquires specialized features of a mammary gland mesenchymal cell. Mammary gland mesenchymal cells form a loosely connected network of cells that surround the mammary ducts.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-05-15T12:17:06Z") +AnnotationAssertion(Annotation( "GOC:dph") "mammary gland mesenchymal cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060610") +AnnotationAssertion(rdfs:label "mesenchymal cell differentiation involved in mammary gland development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (mammary gland fat development) + +AnnotationAssertion(Annotation( "GOC:dph") "The progression of the mammary gland fat over time, from its formation to the mature structure. The mammary fat is an adipose structure in the gland that is invaded by the mammary ducts.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-05-15T12:27:57Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060611") +AnnotationAssertion(rdfs:label "mammary gland fat development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (adipose tissue development) + +AnnotationAssertion(Annotation( "GOC:dph") "The process whose specific outcome is the progression of adipose tissue over time, from its formation to the mature structure. Adipose tissue is specialized tissue that is used to store fat.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-05-15T12:36:28Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:sl") "adipogenesis") +AnnotationAssertion( "GO:0060612") +AnnotationAssertion(rdfs:label "adipose tissue development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (fat pad development) + +AnnotationAssertion(Annotation( "GOC:dph") "The progression of a fat pad from its initial formation to its mature structure. A fat pad is an accumulation of adipose tissue.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-05-15T12:42:08Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060613") +AnnotationAssertion(rdfs:label "fat pad development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (mammary gland bud formation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:12558599") "The morphogenetic process in which a bud forms from the mammary placode. A mammary bud is bulb of epithelial cells that is distinct from the surrounding epidermis.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-05-18T08:43:14Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060615") +AnnotationAssertion(rdfs:label "mammary gland bud formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (mammary gland cord formation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:12558599") "The process in which the mammary gland cord forms by elongation of the mammary bud. The cord is formed once the elongating bud breaks through the mesenchyme and reaches the fat pad.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-05-18T08:57:58Z") +AnnotationAssertion(Annotation( "GOC:dph") "mammary gland sprout formation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060616") +AnnotationAssertion(rdfs:label "mammary gland cord formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (nipple development) + +AnnotationAssertion(Annotation( "GOC:dph") "The progression of the nipple over time, from its formation to the mature structure. The nipple is a part of the mammary gland that protrudes from the surface ectoderm.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-05-18T09:29:38Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060618") +AnnotationAssertion(rdfs:label "nipple development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cell migration involved in mammary placode formation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:12558599") "The orderly movement of epithelial cells within the mammary line that contributes to the formation of the mammary placode.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-05-18T09:41:49Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060619") +AnnotationAssertion(rdfs:label "cell migration involved in mammary placode formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of chromosome condensation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the rate, frequency, or extent of chromosome condensation, the progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis, in eukaryotic cells.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-05-18T02:12:13Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060623") +AnnotationAssertion(rdfs:label "regulation of chromosome condensation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of vesicle-mediated transport) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the rate, frequency, or extent of vesicle-mediated transport, the directed movement of substances, either within a vesicle or in the vesicle membrane, into, out of or within a cell.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-05-18T02:29:43Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060627") +AnnotationAssertion(rdfs:label "regulation of vesicle-mediated transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of microtubule-based movement) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the rate, frequency, or extent of microtubule-based movement, the movement of organelles, other microtubules and other particles along microtubules, mediated by motor proteins.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-05-18T03:07:02Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060632") +AnnotationAssertion(rdfs:label "regulation of microtubule-based movement") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (white fat cell differentiation involved in mammary gland fat development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:12558599") "The process in which a preadipocyte acquires specialized features of a white adipocyte of the mammary gland. White adipocytes have cytoplasmic lipids arranged in a unique vacuole.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-05-27T05:50:56Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060642") +AnnotationAssertion(rdfs:label "white fat cell differentiation involved in mammary gland fat development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (epithelial cell differentiation involved in mammary gland bud morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") "The process in which a cell of the mammary placode becomes a cell of the mammary gland bud.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-05-29T07:58:13Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060643") +AnnotationAssertion(rdfs:label "epithelial cell differentiation involved in mammary gland bud morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (mammary gland epithelial cell differentiation) + +AnnotationAssertion(Annotation( "GOC:dph") "The process in which a relatively unspecialized epithelial cell becomes a more specialized epithelial cell of the mammary gland.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-05-29T08:03:07Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060644") +AnnotationAssertion(rdfs:label "mammary gland epithelial cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (mesenchymal cell condensation involved in mammary fat development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:12558599") "The cell adhesion process in which mammary mesenchyme cells adhere to one another in the initial stages of the formation of mammary fat development.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-05-29T08:33:29Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060647") +AnnotationAssertion(rdfs:label "mesenchymal cell condensation involved in mammary fat development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (mammary gland bud morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:12558599") "The process in which anatomical structures of the mammary gland buds are generated and organized. Mammary gland buds form by an outpocketing of the mammary placodes and grow to invade the mammary fat, when they form the mammary cord.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-05-29T08:42:22Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060648") +AnnotationAssertion(rdfs:label "mammary gland bud morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (mammary gland cord morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:12558599") "The process in which anatomical structures of the mammary gland cord are generated and organized. Mammary gland cords form when the mammary gland bud invades the mammary fat.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-05-29T09:06:56Z") +AnnotationAssertion(Annotation( "GOC:dph") "mammary gland sprout morphogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060652") +AnnotationAssertion(rdfs:label "mammary gland cord morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (epithelial cell differentiation involved in mammary gland cord morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:12558599") "The process in which a relatively unspecialized epithelial cell becomes a more specialized epithelial cell of the mammary gland cord. Epithelial cells of the mammary cord give it its funnel-like shape and some are cornified.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-05-29T09:17:16Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") "epithelial cell differentiation involved in mammary gland sprout morphogenesis") +AnnotationAssertion( "GO:0060653") +AnnotationAssertion(rdfs:label "epithelial cell differentiation involved in mammary gland cord morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (branching involved in mammary gland cord morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:12558599") "The process in which the branching structure of the mammary gland cord is generated and organized. The mammary gland cord is a solid epithelial structure that will hollow out, forming the mammary duct.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-05-29T09:29:32Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060655") +AnnotationAssertion(rdfs:label "branching involved in mammary gland cord morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (nipple morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") "The process in which the nipple is generated and organized.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-05-29T10:45:44Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060658") +AnnotationAssertion(rdfs:label "nipple morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (nipple sheath formation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:12558599") "The developmental process pertaining to the initial formation of the nipple sheath from the unspecified epidermis. This process begins with a circular ingrowth of the epidermis around the region of the mammary sprout. It ends before the region begins to elevate.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-05-29T10:48:39Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060659") +AnnotationAssertion(rdfs:label "nipple sheath formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (epidermis morphogenesis involved in nipple formation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:12558599") "The process in which the epidermis of the nipple sheath is uplifted to form an umbrella-like projection.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-05-29T11:04:04Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060660") +AnnotationAssertion(rdfs:label "epidermis morphogenesis involved in nipple formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (submandibular salivary gland formation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:17336109") "The developmental process pertaining to the initial formation of a submandibular salivary gland. This process begins with a thickening of the epithelium next to the tongue and ends when a bud linked to the oral surface is formed.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-06-01T08:07:16Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060661") +AnnotationAssertion(rdfs:label "submandibular salivary gland formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (epithelial cell proliferation involved in salivary gland morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:17336109") "The multiplication or reproduction of epithelial cells of the submandibular salivary gland, resulting in the expansion of a cell population and the shaping of the gland.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-06-01T08:36:13Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060664") +AnnotationAssertion(rdfs:label "epithelial cell proliferation involved in salivary gland morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (embryonic placenta morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") "The process in which the embryonic placenta is generated and organized.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-06-02T09:33:37Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060669") +AnnotationAssertion(rdfs:label "embryonic placenta morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (branching involved in labyrinthine layer morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:16916377") "The process in which the branches of the fetal placental villi are generated and organized. The villous part of the placenta is called the labyrinth layer.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-06-02T10:40:40Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060670") +AnnotationAssertion(rdfs:label "branching involved in labyrinthine layer morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (epithelial cell differentiation involved in embryonic placenta development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:16916377") "The process in which a trophoblast cell acquires specialized features of an epithelial cell of the placental labyrinthine layer.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-06-02T11:40:52Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060671") +AnnotationAssertion(rdfs:label "epithelial cell differentiation involved in embryonic placenta development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cell-cell signaling involved in placenta development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:16916377") "Any process that mediates the transfer of information from one cell to another.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-06-02T12:58:03Z") +AnnotationAssertion(Annotation( "GOC:mah") "cell-cell signalling involved in placenta development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060673") +AnnotationAssertion(rdfs:label "cell-cell signaling involved in placenta development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (placenta blood vessel development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:16916377") "The process whose specific outcome is the progression of a blood vessel of the placenta over time, from its formation to the mature structure.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-06-02T01:09:43Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060674") +AnnotationAssertion(rdfs:label "placenta blood vessel development") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (ureteric bud morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_kidney_jan10") "The process in which the ureteric bud is generated and organized.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-06-02T01:31:41Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060675") +AnnotationAssertion(rdfs:label "ureteric bud morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (ureteric bud formation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:16916378") "The developmental process pertaining to the initial formation of the ureteric bud from the Wolffian duct. This process begins when the bud protrudes from the duct and ends when it is a recognizable bud.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-06-02T01:47:23Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060676") +AnnotationAssertion(rdfs:label "ureteric bud formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (ureteric bud elongation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:16916378") "The developmental growth in which the ureteric bud grows along its axis beginning with the growth of the primary ureteric bud and ending when the branches of the bud have elongated.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-06-02T02:13:29Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060677") +AnnotationAssertion(rdfs:label "ureteric bud elongation") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (lateral sprouting involved in ureteric bud morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:16916378") "The process in which a branch forms along the side of a ureteric bud.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-06-02T02:44:27Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060680") +AnnotationAssertion(rdfs:label "lateral sprouting involved in ureteric bud morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (primary ureteric bud growth) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:16916378") "The process in which the primary ureteric bud grows along its axis dorsally toward the metanephric blastema.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-06-02T02:56:01Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060682") +AnnotationAssertion(rdfs:label "primary ureteric bud growth") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (regulation of prostatic bud formation) + +AnnotationAssertion(Annotation( "GOC:dph") "Any process that modulates the rate, frequency, or extent of prostatic bud formation, the morphogenetic process in which a region of the fetal urogenital sinus epithelium is specified to become the prostate, resulting in prostate bud outgrowth.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-06-05T12:29:26Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060685") +AnnotationAssertion(rdfs:label "regulation of prostatic bud formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (negative regulation of prostatic bud formation) + +AnnotationAssertion(Annotation( "GOC:dph") "Any process that decreases the rate, frequency, or extent of prostatic bud formation, the morphogenetic process in which a region of the fetal urogenital sinus epithelium is specified to become the prostate, resulting in prostate bud outgrowth.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-06-05T12:35:25Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060686") +AnnotationAssertion(rdfs:label "negative regulation of prostatic bud formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of branching involved in prostate gland morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") "Any process that modulates the rate, frequency, or extent of prostate gland branching, the process in which the branching structure of the prostate gland is generated and organized. A branch is a division or offshoot from a main stem.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-06-05T12:37:14Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060687") +AnnotationAssertion(rdfs:label "regulation of branching involved in prostate gland morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of morphogenesis of a branching structure) + +AnnotationAssertion(Annotation( "GOC:dph") "Any process that modulates the rate, frequency, or extent of branching morphogenesis, the process in which the anatomical structures of branches are generated and organized.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-06-05T12:41:44Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060688") +AnnotationAssertion(rdfs:label "regulation of morphogenesis of a branching structure") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (cell differentiation involved in salivary gland development) + +AnnotationAssertion(Annotation( "GOC:dph") "The process in which a relatively unspecialized cell acquires specialized structural and/or functional features that characterize the cells of the salivary gland.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-06-08T01:01:35Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060689") +AnnotationAssertion(rdfs:label "cell differentiation involved in salivary gland development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (epithelial cell differentiation involved in salivary gland development) + +AnnotationAssertion(Annotation( "GOC:dph") "The process in which a relatively unspecialized cell acquire specialized structural and/or functional features of an epithelial cell of the salivary gland.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-06-08T01:04:19Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060690") +AnnotationAssertion(rdfs:label "epithelial cell differentiation involved in salivary gland development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (epithelial cell maturation involved in salivary gland development) + +AnnotationAssertion(Annotation( "GOC:dph") "The developmental process, independent of morphogenetic (shape) change, that is required for an epithelial cell of the salivary gland to attain its fully functional state.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-06-08T01:06:00Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060691") +AnnotationAssertion(rdfs:label "epithelial cell maturation involved in salivary gland development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (mesenchymal cell differentiation involved in salivary gland development) + +AnnotationAssertion(Annotation( "GOC:dph") "The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal cell of the salivary gland. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-06-08T01:08:44Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060692") +AnnotationAssertion(rdfs:label "mesenchymal cell differentiation involved in salivary gland development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of branching involved in salivary gland morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") "Any process that modulates the rate, frequency, or extent of branching morphogenesis in the salivary gland epithelium.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-06-08T01:14:44Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060693") +AnnotationAssertion(rdfs:label "regulation of branching involved in salivary gland morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of phospholipid catabolic process) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the rate, frequency, or extent of phospholipid catabolism, the chemical reactions and pathways resulting in the breakdown of phospholipids, any lipid containing phosphoric acid as a mono- or diester.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-06-08T02:25:45Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060696") +AnnotationAssertion(rdfs:label "regulation of phospholipid catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of phospholipid catabolic process) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that increases the rate, frequency, or extent of phospholipid catabolism, the chemical reactions and pathways resulting in the breakdown of phospholipids, any lipid containing phosphoric acid as a mono- or diester.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-06-08T02:28:38Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060697") +AnnotationAssertion(rdfs:label "positive regulation of phospholipid catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (acinar cell differentiation involved in salivary gland development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "The process in which a relatively unspecialized cell acquires specialized structural and/or functional features that characterize an acinar cell of the salivary gland. Acinar cells are protein-secreting cells in the gland.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-06-09T09:32:46Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060704") +AnnotationAssertion(rdfs:label "acinar cell differentiation involved in salivary gland development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (neuron differentiation involved in salivary gland development) + +AnnotationAssertion(Annotation( "GOC:dph") "The process in which a relatively unspecialized cell acquires specialized structural and/or functional features that characterize the neurons of the salivary gland.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-06-09T09:35:52Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060705") +AnnotationAssertion(rdfs:label "neuron differentiation involved in salivary gland development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (cell differentiation involved in embryonic placenta development) + +AnnotationAssertion(Annotation( "GOC:dph") "The process in which a relatively unspecialized cell acquires specialized features of the embryonic placenta.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-06-09T10:26:42Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060706") +AnnotationAssertion(rdfs:label "cell differentiation involved in embryonic placenta development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (spongiotrophoblast differentiation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:16269175") "The process in which a relatively unspecialized cell of the ectoplacental cone acquires specialized features of a spongiotrophoblast of the placenta. A spongiotrophoblast cell is a basophilic cell.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-06-09T10:38:10Z") +AnnotationAssertion(Annotation( "GOC:cjm") "spongiotrophoblast cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060708") +AnnotationAssertion(rdfs:label "spongiotrophoblast differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (labyrinthine layer development) + +AnnotationAssertion(Annotation( "GOC:dph") "The process in which the labyrinthine layer of the placenta progresses, from its formation to its mature state.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-06-09T03:27:43Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060711") +AnnotationAssertion(rdfs:label "labyrinthine layer development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (spongiotrophoblast layer development) + +AnnotationAssertion(Annotation( "GOC:dph") "The process in which the spongiotrophoblast layer of the placenta progresses from its formation to its mature state.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-06-09T03:33:40Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060712") +AnnotationAssertion(rdfs:label "spongiotrophoblast layer development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (labyrinthine layer morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") "The process in which the labyrinthine layer of the placenta is generated and organized.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-06-10T08:10:19Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060713") +AnnotationAssertion(rdfs:label "labyrinthine layer morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (labyrinthine layer formation) + +AnnotationAssertion(Annotation( "GOC:dph") "The developmental process pertaining to the initial formation of the labyrinthine layer of the placenta.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-06-10T08:13:14Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060714") +AnnotationAssertion(rdfs:label "labyrinthine layer formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (labyrinthine layer blood vessel development) + +AnnotationAssertion(Annotation( "GOC:dph") "The process whose specific outcome is the progression of a blood vessel of the labyrinthine layer of the placenta over time, from its formation to the mature structure. The embryonic vessels grow through the layer to come in close contact with the maternal blood supply.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-06-11T09:04:38Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060716") +AnnotationAssertion(rdfs:label "labyrinthine layer blood vessel development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (chorion development) + +AnnotationAssertion(Annotation( "GOC:dph") "The biological process whose specific outcome is the progression of a chorion from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The chorion is an extraembryonic membrane.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-06-11T02:37:50Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060717") +AnnotationAssertion(rdfs:label "chorion development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (chorionic trophoblast cell differentiation) + +AnnotationAssertion(Annotation( "CL:0011101") Annotation( "GOC:dph") Annotation( "PMID:16983341") "The process in which relatively unspecialized cells of the ectoplacental cone acquire specialized structural and/or functional features that characterize chorionic trophoblasts. These cells will migrate towards the spongiotrophoblast layer and give rise to syncytiotrophoblasts of the labyrinthine layer.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-06-11T02:48:27Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060718") +AnnotationAssertion(rdfs:label "chorionic trophoblast cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (chorionic trophoblast cell development) + +AnnotationAssertion(Annotation( "CL:0011101") Annotation( "GOC:16983341") Annotation( "GOC:dph") "The process whose specific outcome is the progression of the chorionic trophoblast over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-06-11T02:58:45Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060719") +AnnotationAssertion(rdfs:label "chorionic trophoblast cell development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cell proliferation involved in embryonic placenta development) + +AnnotationAssertion(Annotation( "GOC:dph") "The multiplication or reproduction of cells, resulting in the expansion of the population in the embryonic placenta.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-06-12T12:46:04Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060722") +AnnotationAssertion(rdfs:label "cell proliferation involved in embryonic placenta development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of cell proliferation involved in embryonic placenta development) + +AnnotationAssertion(Annotation( "GOC:dph") "Any process that modulates the rate, frequency, or extent of cell proliferation involved in embryonic placenta development.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-06-12T12:50:23Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060723") +AnnotationAssertion(rdfs:label "regulation of cell proliferation involved in embryonic placenta development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (prostate gland growth) + +AnnotationAssertion(Annotation( "GOC:dph") "The increase in size or mass of the prostate gland where the increase in size or mass has the specific outcome of the progression of the gland, from its formation to its mature state.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-06-15T09:21:52Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060736") +AnnotationAssertion(rdfs:label "prostate gland growth") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (prostate gland morphogenetic growth) + +AnnotationAssertion(Annotation( "GOC:dph") "The differential increase in size or mass of the prostate gland that contributes to the gland attaining its form.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-06-15T09:24:40Z") +AnnotationAssertion(Annotation( "GOC:dph") "prostate gland growth involved in morphogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060737") +AnnotationAssertion(rdfs:label "prostate gland morphogenetic growth") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (prostate gland epithelium morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") "The process in which the anatomical structures of epithelia of the prostate gland are generated and organized. An epithelium consists of closely packed cells arranged in one or more layers, that covers the outer surfaces of the body or lines any internal cavity or tube.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-06-16T09:23:22Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060740") +AnnotationAssertion(rdfs:label "prostate gland epithelium morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (prostate gland stromal morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") "The process in which the prostate gland stroma is generated and organized. The prostate gland stroma is made up of the mesenchymal or fibroblast cells of the prostate gland.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-06-16T09:27:01Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060741") +AnnotationAssertion(rdfs:label "prostate gland stromal morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (epithelial cell differentiation involved in prostate gland development) + +AnnotationAssertion(Annotation( "GOC:dph") "The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell of the prostate gland.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-06-16T09:32:34Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060742") +AnnotationAssertion(rdfs:label "epithelial cell differentiation involved in prostate gland development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (epithelial cell maturation involved in prostate gland development) + +AnnotationAssertion(Annotation( "GOC:dph") "The developmental process, independent of morphogenetic (shape) change, that is required for an epithelial cell of the prostate gland to attain its fully functional state. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-06-16T09:34:42Z") +AnnotationAssertion(Annotation( "GOC:dph") "prostate gland epithelial cell development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060743") +AnnotationAssertion(rdfs:label "epithelial cell maturation involved in prostate gland development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (mammary gland alveolus development) + +AnnotationAssertion(Annotation( "GOC:dph") "The progression of the mammary gland alveolus over time, from its formation to its mature state. The mammary gland alveolus is a sac-like structure that is found in the mature gland.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-06-22T10:52:12Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060749") +AnnotationAssertion(rdfs:label "mammary gland alveolus development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (regulation of response to cytokine stimulus) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the rate, frequency, or extent of a response to cytokine stimulus.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-06-22T02:56:12Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060759") +AnnotationAssertion(rdfs:label "regulation of response to cytokine stimulus") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of response to cytokine stimulus) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that increases the rate, frequency, or extent of a response to cytokine stimulus.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-06-22T02:58:04Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060760") +AnnotationAssertion(rdfs:label "positive regulation of response to cytokine stimulus") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of response to cytokine stimulus) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that decreases the rate, frequency, or extent of a response to cytokine stimulus.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-06-22T02:59:57Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060761") +AnnotationAssertion(rdfs:label "negative regulation of response to cytokine stimulus") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of branching involved in mammary gland duct morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") "Any process that modulates the rate, frequency, or extent of branching involved in mammary gland duct morphogenesis.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-06-22T05:20:33Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060762") +AnnotationAssertion(rdfs:label "regulation of branching involved in mammary gland duct morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (mammary duct terminal end bud growth) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:10804170") "The morphogenetic growth of the large, club-shaped terminal end of a mammary gland duct during prepubertal growth and during puberty.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-07-06T07:33:50Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060763") +AnnotationAssertion(rdfs:label "mammary duct terminal end bud growth") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cell-cell signaling involved in mammary gland development) + +AnnotationAssertion(Annotation( "GOC:dph") "Any process that mediates the transfer of information from one cell to another and contributes to the progression of the mammary gland, from its initial state to the mature structure.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-07-06T09:24:53Z") +AnnotationAssertion(Annotation( "GOC:mah") "cell-cell signalling involved in mammary gland development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060764") +AnnotationAssertion(rdfs:label "cell-cell signaling involved in mammary gland development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (epithelial cell proliferation involved in prostate gland development) + +AnnotationAssertion(Annotation( "GOC:dph") "The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population that contributes to the progression of the prostate gland over time.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-07-08T07:32:34Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060767") +AnnotationAssertion(rdfs:label "epithelial cell proliferation involved in prostate gland development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of epithelial cell proliferation involved in prostate gland development) + +AnnotationAssertion(Annotation( "GOC:dph") "Any process that modulates the rate, frequency or extent of epithelial cell proliferation that contributes to the progression of the prostate gland over time.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-07-08T07:34:56Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060768") +AnnotationAssertion(rdfs:label "regulation of epithelial cell proliferation involved in prostate gland development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of epithelial cell proliferation involved in prostate gland development) + +AnnotationAssertion(Annotation( "GOC:dph") "Any process that increases the rate, frequency or extent of epithelial cell proliferation that contributes to the progression of the prostate gland over time.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-07-08T07:38:02Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060769") +AnnotationAssertion(rdfs:label "positive regulation of epithelial cell proliferation involved in prostate gland development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (negative regulation of epithelial cell proliferation involved in prostate gland development) + +AnnotationAssertion(Annotation( "GOC:dph") "Any process that decreases the rate, frequency or extent of epithelial cell proliferation that contributes to the progression of the prostate gland over time.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-07-08T07:40:27Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060770") +AnnotationAssertion(rdfs:label "negative regulation of epithelial cell proliferation involved in prostate gland development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (mesenchymal cell proliferation involved in prostate gland development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:12221011") "The multiplication or reproduction of mesenchymal cells, resulting in the expansion of a cell population that contributes to the progression of the prostate gland over time.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-07-28T11:50:56Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060781") +AnnotationAssertion(rdfs:label "mesenchymal cell proliferation involved in prostate gland development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of mesenchymal cell proliferation involved in prostate gland development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:12221011") "Any process that modulates the frequency, rate or extent of mesenchymal cell proliferation that contributes to the progression of the prostate gland over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-07-28T11:54:20Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060782") +AnnotationAssertion(rdfs:label "regulation of mesenchymal cell proliferation involved in prostate gland development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of cell proliferation involved in tissue homeostasis) + +AnnotationAssertion(Annotation( "GOC:dph") "Any process that modulates the frequency, rate or extent of cell proliferation resulting in the maintenance of a steady-state number of cells within a tissue.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-07-31T01:46:28Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060784") +AnnotationAssertion(rdfs:label "regulation of cell proliferation involved in tissue homeostasis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (regulation of apoptosis involved in tissue homeostasis) + +AnnotationAssertion(Annotation( "GOC:dph") "Any process that modulates the occurrence or rate of cell death by apoptosis that results in the maintenance of the steady-state number of cells within a tissue.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-07-31T01:49:54Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060785") +AnnotationAssertion(rdfs:label "regulation of apoptosis involved in tissue homeostasis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (regulation of cell differentiation involved in tissue homeostasis) + +AnnotationAssertion(Annotation( "GOC:dph") "Any process that modulates the frequency, rate or extent of cell differentiation that contributes to the maintenance of a steady state of a cell type within a tissue.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-07-31T01:55:19Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060786") +AnnotationAssertion(rdfs:label "regulation of cell differentiation involved in tissue homeostasis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (ectodermal placode formation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:sdb_2009") Annotation( "GOC:tb") "The developmental process in which an ectodermal placode forms. An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-08-04T12:15:57Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060788") +AnnotationAssertion(rdfs:label "ectodermal placode formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (hair follicle placode formation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:sdb_2009") Annotation( "GOC:tb") "The developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-08-04T12:18:26Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060789") +AnnotationAssertion(rdfs:label "hair follicle placode formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (tooth placode formation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:sdb_2009") Annotation( "GOC:tb") "The developmental process in which the tooth placode forms. A tooth placode is a thickening of the ectoderm that will give rise to the tooth bud.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-08-04T12:21:47Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060790") +AnnotationAssertion(rdfs:label "tooth placode formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (sebaceous gland placode formation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:sdb_2009") Annotation( "GOC:tb") "The developmental process in which a sebaceous gland placode forms. A sebaceous gland placode is a thickening of the ectoderm that will give rise to the sebaceous gland bud.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-08-04T12:23:09Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060791") +AnnotationAssertion(rdfs:label "sebaceous gland placode formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (sweat gland development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:sdb_2009") Annotation( "GOC:tb") "The progression of the sweat gland over time, from its formation to the mature structure. Sweat glands secrete an aqueous solution that is used in thermoregulation.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-08-04T12:35:12Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060792") +AnnotationAssertion(rdfs:label "sweat gland development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (sweat gland placode formation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:sdb_2009") Annotation( "GOC:tb") "The developmental process in which the sweat gland placode forms. An sweat gland placode is a thickening of the ectoderm that will give rise to the sweat gland bud.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-08-04T12:38:10Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060793") +AnnotationAssertion(rdfs:label "sweat gland placode formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cell fate commitment involved in formation of primary germ layer) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:sdb_2009") Annotation( "GOC:tb") "The commitment of cells to specific cell fates of the endoderm, ectoderm, or mesoderm as a part of gastrulation.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-08-04T03:11:22Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060795") +AnnotationAssertion(rdfs:label "cell fate commitment involved in formation of primary germ layer") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of cell differentiation involved in embryonic placenta development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:sdb_2009") Annotation( "GOC:tb") "Any process that modulates the rate, frequency or extent of cell differentiation that contributes to the progression of the placenta over time, from its initial condition to its mature state.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-08-06T01:20:25Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060800") +AnnotationAssertion(rdfs:label "regulation of cell differentiation involved in embryonic placenta development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of cell differentiation involved in embryonic placenta development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:sdb_2009") Annotation( "GOC:tb") "Any process that decreases the rate, frequency or extent of cell differentiation that contributes to the progression of the placenta over time, from its initial condition to its mature state.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-08-06T02:02:18Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060806") +AnnotationAssertion(rdfs:label "negative regulation of cell differentiation involved in embryonic placenta development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of translation involved in anterior/posterior axis specification) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:sdb_2009") Annotation( "GOC:tb") "Any process that modulates the frequency, rate or extent of translation of mRNAs that contribute to the specification of the anterior/posterior axis.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-08-07T10:02:31Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060815") +AnnotationAssertion(rdfs:label "regulation of translation involved in anterior/posterior axis specification") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (lymphatic endothelial cell differentiation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:sdb_2009") Annotation( "GOC:tb") "The process in which a venous blood vessel endothelial cell acquires specialized features of a lymphatic vessel endothelial cell, a thin flattened cell that lines the inside surfaces of lymph vessels.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-08-11T03:45:20Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060836") +AnnotationAssertion(rdfs:label "lymphatic endothelial cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (blood vessel endothelial cell differentiation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:sdb_2009") Annotation( "GOC:tb") "The process in which a relatively unspecialized cell acquires specialized features of a blood vessel endothelial cell, a thin flattened cell that lines the inside surfaces of blood vessels.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-08-11T03:47:36Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060837") +AnnotationAssertion(rdfs:label "blood vessel endothelial cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (artery development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:sdb_2009") Annotation( "GOC:tb") "The progression of the artery over time, from its initial formation to the mature structure. An artery is a blood vessel that carries blood away from the heart to a capillary bed.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-08-12T10:10:51Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060840") +AnnotationAssertion(rdfs:label "artery development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (venous blood vessel development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:sdb_2009") Annotation( "GOC:tb") "The progression of the venous blood vessel over time from its initial formation to the mature structure. Venous blood vessels carry blood back to the heart after the capillary bed.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-08-12T10:14:07Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060841") +AnnotationAssertion(rdfs:label "venous blood vessel development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (arterial endothelial cell differentiation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:sdb_2009") Annotation( "GOC:tb") "The process in which a relatively unspecialized endothelial cell acquires specialized features of an arterial endothelial cell, a thin flattened cell that lines the inside surfaces of arteries.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-08-12T10:41:34Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060842") +AnnotationAssertion(rdfs:label "arterial endothelial cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (venous endothelial cell differentiation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:sdb_2009") Annotation( "GOC:tb") "The process in which a relatively unspecialized endothelial cell acquires specialized features of a venous endothelial cell, a thin flattened cell that lines the inside surfaces of veins.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-08-12T10:43:40Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060843") +AnnotationAssertion(rdfs:label "venous endothelial cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (branching involved in lymph vessel morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:sdb_2009") Annotation( "GOC:tb") "The process of the coordinated growth and sprouting of lymph vessels giving rise to the organized lymphatic system.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-08-12T12:00:48Z") +AnnotationAssertion(Annotation( "GOC:dph") "patterning of lymph vessels") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060854") +AnnotationAssertion(rdfs:label "branching involved in lymph vessel morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (semicircular canal development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:sdb_2009") Annotation( "GOC:tb") "The progression of the semicircular canal from its initial formation to the mature structure.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-08-13T09:36:37Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060872") +AnnotationAssertion(rdfs:label "semicircular canal development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (anterior semicircular canal development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:sdb_2009") Annotation( "GOC:tb") "The progession of the anterior semicircular canal from its initial formation to the mature structure.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-08-13T09:39:49Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060873") +AnnotationAssertion(rdfs:label "anterior semicircular canal development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (posterior semicircular canal development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:sdb_2009") Annotation( "GOC:tb") "The progession of the posterior semicircular canal from its initial formation to the mature structure.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-08-13T09:42:39Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060874") +AnnotationAssertion(rdfs:label "posterior semicircular canal development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (lateral semicircular canal development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:sdb_2009") Annotation( "GOC:tb") "The progession of the lateral semicircular canal from its initial formation to the mature structure.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-08-13T09:43:25Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060875") +AnnotationAssertion(rdfs:label "lateral semicircular canal development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (semicircular canal formation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:sdb_2009") Annotation( "GOC:tb") "The developmental process pertaining to the initial formation of the semicircular canal from the otic vesicle. This process begins with the regionalization of the vesicle that specifies the area where the vesicles will form and continues through the process of fusion which forms the initial tubes.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-08-13T09:45:07Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060876") +AnnotationAssertion(rdfs:label "semicircular canal formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (regionalization involved in semicircular canal formation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:sdb_2009") Annotation( "GOC:tb") "The pattern specification process that results in the subdivision of the otic epithelium in space to define an area or volume in which cells will differentiate to give rise to the semicircular canals.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-08-13T09:56:45Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060877") +AnnotationAssertion(rdfs:label "regionalization involved in semicircular canal formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (pouch outgrowth involved in semicircular canal formation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:sdb_2009") Annotation( "GOC:tb") "The morphogenetic process in which an epithelial sheet bends along a linear axis and gives rise to a pouch that will form a semicircular canal.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-08-13T10:01:01Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060878") +AnnotationAssertion(rdfs:label "pouch outgrowth involved in semicircular canal formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (semicircular canal fusion) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:sdb_2009") Annotation( "GOC:tb") "Creation of the central hole of the semicircular canal by sealing the edges of the pouch that forms during the process of semicircular canal formation.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-08-13T10:05:51Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060879") +AnnotationAssertion(rdfs:label "semicircular canal fusion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cell morphogenesis involved in semicircular canal fusion) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:sdb_2009") Annotation( "GOC:tb") "The change in form (cell shape and size) that occurs when a semicircular canal epithelial cell acquires the structural features that allow it to contribute to the process of semicircular canal fusion.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-08-13T10:13:25Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060880") +AnnotationAssertion(rdfs:label "cell morphogenesis involved in semicircular canal fusion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (basement membrane disassembly involved in semicircular canal fusion) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:sdb_2009") Annotation( "GOC:tb") "A process that results in the breakdown of the basement membrane that contributes to the process of semicircular canal fusion.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-08-13T11:29:52Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "basal lamina disassembly involved in semicircular canal fusion") +AnnotationAssertion( "GO:0060882") +AnnotationAssertion(rdfs:label "basement membrane disassembly involved in semicircular canal fusion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (limb epidermis development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:sdb_2009") Annotation( "GOC:tb") "The process whose specific outcome is the progression of the epidermis of the limb over time, from its formation to the mature structure. The limb epidermis is the outer epithelial layer of the limb, it is a complex stratified squamous epithelium.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-08-13T12:39:39Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060887") +AnnotationAssertion(rdfs:label "limb epidermis development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (neural plate pattern specification) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:sdb_2009") Annotation( "GOC:tb") "The developmental process that results in the creation of defined areas or spaces within the neural plate to which cells respond and eventually are instructed to differentiate.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-08-13T02:06:27Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060896") +AnnotationAssertion(rdfs:label "neural plate pattern specification") +SubClassOf( ) + +# Class: (neural plate regionalization) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:sdb_2009") Annotation( "GOC:tb") "The pattern specification process that results in the subdivision of an axis or axes of the neural plate in space to define an area or volume in which specific patterns of cell differentiation will take place or in which cells interpret a specific environment.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-08-13T02:09:04Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060897") +AnnotationAssertion(rdfs:label "neural plate regionalization") +SubClassOf( ) +SubClassOf( ) + +# Class: (embryonic camera-type eye formation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:sdb_2009") Annotation( "GOC:tb") "The developmental process pertaining to the initial formation of a camera-type eye from unspecified neurectoderm. This process begins with the differentiation of cells that form the optic field and ends when the optic cup has attained its shape.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-08-13T02:26:54Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060900") +AnnotationAssertion(rdfs:label "embryonic camera-type eye formation") +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (positive regulation of macrophage cytokine production) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that increases the rate, frequency or extent of macrophage cytokine production. Macrophage cytokine production is the appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-09-04T02:32:18Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060907") +AnnotationAssertion(rdfs:label "positive regulation of macrophage cytokine production") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (heart formation) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The developmental process pertaining to the initial formation of the heart from unspecified parts. This process begins with the specific processes that contribute to the appearance of the heart field and the arrival of cardiac neural crest to the heart region. The process ends when the structural rudiment is recognizable.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-09-17T09:02:13Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:mtg_heart") "cardiogenesis") +AnnotationAssertion( "GO:0060914") +AnnotationAssertion(rdfs:label "heart formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (mesenchymal cell differentiation involved in lung development) + +AnnotationAssertion(Annotation( "GOC:dph") "The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal cell of the lung. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-09-18T11:45:33Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060915") +AnnotationAssertion(rdfs:label "mesenchymal cell differentiation involved in lung development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (mesenchymal cell proliferation involved in lung development) + +AnnotationAssertion(Annotation( "GOC:dph") "The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population that contributes to the progression of the lung over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-09-18T11:50:17Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060916") +AnnotationAssertion(rdfs:label "mesenchymal cell proliferation involved in lung development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (cardiac pacemaker cell differentiation) + +AnnotationAssertion(Annotation( "GOC:mtg_cardiac_conduct_nov11") Annotation( "GOC:mtg_heart") "The process in which a relatively unspecialized cell acquires specialized features of a pacemaker cell. Pacemaker cells are specialized cardiomyocytes that are responsible for regulating the timing of heart contractions.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-09-29T11:01:31Z") +AnnotationAssertion( "pacemaker cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060920") +AnnotationAssertion(rdfs:label "cardiac pacemaker cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (sinoatrial node cell differentiation) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which a relatively unspecialized cell acquires specialized features of a sinoatrial (SA) node cell. SA node cells are pacemaker cells that are found in the sinoatrial node.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-09-29T11:03:30Z") +AnnotationAssertion(Annotation( "GOC:mtg_heart") "SA node cell differentiation") +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mtg_cardiac_conduct_nov11") "SAN cell differentiation") +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mtg_cardiac_conduct_nov11") "sinus node cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060921") +AnnotationAssertion(rdfs:label "sinoatrial node cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (atrioventricular node cell differentiation) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which a relatively unspecialized cell acquires specialized features of an atrioventricular (AV) node cell. AV node cells are pacemaker cells that are found in the atrioventricular node.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-09-29T11:07:06Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:mtg_heart") "AV node cell differentiation") +AnnotationAssertion( "GO:0060922") +AnnotationAssertion(rdfs:label "atrioventricular node cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cardiac pacemaker cell development) + +AnnotationAssertion(Annotation( "GOC:mtg_cardiac_conduct_nov11") Annotation( "GOC:mtg_heart") "The process whose specific outcome is the progression of a pacemaker cell over time, from its formation to the mature state. Pacemaker cells are specialized cardiomyocytes that are responsible for regulating the timing of heart contractions.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-09-29T11:51:55Z") +AnnotationAssertion( "pacemaker cell development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060926") +AnnotationAssertion(rdfs:label "cardiac pacemaker cell development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (atrioventricular node cell development) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process whose specific outcome is the progression of an atrioventricular (AV) node cell over time, from its formation to the mature state.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-09-29T11:59:26Z") +AnnotationAssertion(Annotation( "GOC:mtg_heart") "AV node cell development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060928") +AnnotationAssertion(rdfs:label "atrioventricular node cell development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (sinoatrial node cell development) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process whose specific outcome is the progression of a sinoatrial (SA) node cell over time, from its formation to the mature state. SA node cells are pacemaker cells that are found in the sinoatrial node.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-09-29T12:05:47Z") +AnnotationAssertion(Annotation( "GOC:mtg_heart") "SA node cell development") +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mtg_cardiac_conduct_nov11") "SAN cell development") +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mtg_cardiac_conduct_nov11") "sinus node cell development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060931") +AnnotationAssertion(rdfs:label "sinoatrial node cell development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (His-Purkinje system cell differentiation) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell of the His-Purkinje system. These cells form the fibers regulate cardiac muscle contraction in the ventricles.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-09-29T01:10:32Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060932") +AnnotationAssertion(rdfs:label "His-Purkinje system cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (His-Purkinje system cell development) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process whose specific outcome is the progression of a His-Purkinje cell over time, from its formation to the mature state. These cells form the fibers that regulate cardiac muscle contraction in the ventricles.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-09-29T01:15:02Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060933") +AnnotationAssertion(rdfs:label "His-Purkinje system cell development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cardiac fibroblast cell differentiation) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cardiac fibroblast. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-09-29T01:20:04Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060935") +AnnotationAssertion(rdfs:label "cardiac fibroblast cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (cardiac fibroblast cell development) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process whose specific outcome is the progression of a cardiac fibroblast over time, from its formation to the mature state. A cardiac fibroblast is a connective tissue cell of the heart which secretes an extracellular matrix rich in collagen and other macromolecules.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-09-29T01:23:03Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060936") +AnnotationAssertion(rdfs:label "cardiac fibroblast cell development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cardiac neuron differentiation) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which a relatively unspecialized cell acquires specialized features of a neuron of the heart.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-09-29T02:45:33Z") +AnnotationAssertion(Annotation( "GOC:mtg_heart") "heart neuron differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060945") +AnnotationAssertion(rdfs:label "cardiac neuron differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cardiac blood vessel endothelial cell differentiation) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which a relatively unspecialized cell acquires specialized features of a blood vessel endothelial cell of the heart. Blood vessel endothelial cells are thin flattened cells that line the inside surfaces of blood vessels.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-09-29T02:48:55Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060946") +AnnotationAssertion(rdfs:label "cardiac blood vessel endothelial cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (cardiac glial cell differentiation) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which a relatively unspecialized cell acquires the specialized features of a glial cell of the heart.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-09-29T03:06:37Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060950") +AnnotationAssertion(rdfs:label "cardiac glial cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (cardiac glial cell development) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process aimed at the progression of a cardiac glial cell over time, from its formation to the fully functional mature cell.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-09-29T03:09:24Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060952") +AnnotationAssertion(rdfs:label "cardiac glial cell development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (endocardial cell differentiation) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an endocardial cell. An endocardial cell is a specialized endothelial cell that makes up the endocardium portion of the heart. The endocardium is the innermost layer of tissue of the heart, and lines the heart chambers.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-09-29T03:20:39Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060956") +AnnotationAssertion(rdfs:label "endocardial cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (endocardial cell development) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The progression of an endocardial cell over time, from its formation to the mature cell. An endocardial cell is a specialized endothelial cell that makes up the endocardium portion of the heart.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-09-29T03:26:59Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060958") +AnnotationAssertion(rdfs:label "endocardial cell development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cardiac neuron development) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process whose specific outcome is the progression of a cardiac neuron over time, from its formation to the mature state.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-09-30T10:14:56Z") +AnnotationAssertion(Annotation( "GOC:mtg_heart") "heart neuron development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060959") +AnnotationAssertion(rdfs:label "cardiac neuron development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cell migration involved in heart development) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The orderly movement of a cell from one site to another that will contribute to the progression of the heart over time, from its initial formation, to the mature organ.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-06T10:53:49Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060973") +AnnotationAssertion(rdfs:label "cell migration involved in heart development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (cell migration involved in heart formation) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The orderly movement of a cell from one site to another that contribute to the formation of the heart. The initial heart structure is made up of mesoderm-derived heart progenitor cells and neural crest-derived cells.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-06T10:56:33Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060974") +AnnotationAssertion(rdfs:label "cell migration involved in heart formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (coronary vasculature development) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process whose specific outcome is the progression of the blood vessels of the heart over time, from its formation to the mature structure.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-06T12:15:23Z") +AnnotationAssertion(Annotation( "GOC:mtg_heart") "cardiac blood vessel development") +AnnotationAssertion(Annotation( "GOC:mtg_heart") "cardiac vasculature development") +AnnotationAssertion(Annotation( "GOC:mtg_heart") "coronary blood vessel development") +AnnotationAssertion(Annotation( "GOC:mtg_heart") "heart blood vessel development") +AnnotationAssertion(Annotation( "GOC:mtg_heart") "heart vasculature development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060976") +AnnotationAssertion(rdfs:label "coronary vasculature development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (coronary vasculature morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which the anatomical structures of blood vessels of the heart are generated and organized. The blood vessel is the vasculature carrying blood.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-06T12:28:23Z") +AnnotationAssertion(Annotation( "GOC:mtg_heart") "cardiac blood vessel morphogenesis") +AnnotationAssertion(Annotation( "GOC:mtg_heart") "cardiac vasculature morphogenesis") +AnnotationAssertion(Annotation( "GOC:mtg_heart") "coronary blood vessel morphogenesis") +AnnotationAssertion(Annotation( "GOC:mtg_heart") "heart blood vessel morphogenesis") +AnnotationAssertion(Annotation( "GOC:mtg_heart") "heart vasculature morphogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060977") +AnnotationAssertion(rdfs:label "coronary vasculature morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (angiogenesis involved in coronary vascular morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "Blood vessel formation in the heart when new vessels emerge from the proliferation of pre-existing blood vessels.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-06T02:02:12Z") +AnnotationAssertion(Annotation( "GOC:mtg_heart") "angiogenesis involved in cardiac vascular morphogenesis") +AnnotationAssertion(Annotation( "GOC:mtg_heart") "angiogenesis involved in heart vascular morphogenesis") +AnnotationAssertion(Annotation( "GOC:mtg_heart") "coronary blood vessel angiogenesis") +AnnotationAssertion(Annotation( "GOC:mtg_heart") "coronary vasculature angiogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060978") +AnnotationAssertion(rdfs:label "angiogenesis involved in coronary vascular morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (vasculogenesis involved in coronary vascular morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The differentiation of endothelial cells from progenitor cells that contributes to blood vessel development in the heart, and the de novo formation of blood vessels and tubes.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-06T02:19:42Z") +AnnotationAssertion(Annotation( "GOC:mtg_heart") "coronary vasculogenesis") +AnnotationAssertion(Annotation( "GOC:mtg_heart") "vasculogenesis involved in coronary blood vessel morphogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060979") +AnnotationAssertion(rdfs:label "vasculogenesis involved in coronary vascular morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (cell migration involved in coronary vasculogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The orderly movement of a cell from one site to another that will contribute to the differentiation of an endothelial cell that will form the blood vessels of the heart.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-06T02:33:06Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060980") +AnnotationAssertion(rdfs:label "cell migration involved in coronary vasculogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (cell migration involved in coronary angiogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The orderly movement of a cell from one site to another that will contribute to the formation of new blood vessels in the heart from pre-existing blood vessels.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-06T02:49:12Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060981") +AnnotationAssertion(rdfs:label "cell migration involved in coronary angiogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (coronary artery morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_heart") "The process in which the anatomical structures of coronary arteries are generated and organized. Coronary arteries are blood vessels that transport blood to the heart muscle.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2009-10-06T02:58:52Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060982") +AnnotationAssertion(rdfs:label "coronary artery morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + # Class: (endocrine hormone secretion) AnnotationAssertion(Annotation( "GOC:dph") "The regulated release of a hormone into the circulatory system.") @@ -39996,6 +100289,63 @@ AnnotationAssertion(rdfs:label "endo SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (kidney morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_kidney_jan10") "Morphogenesis of a kidney. A kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-01-19T08:16:55Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060993") +AnnotationAssertion(rdfs:label "kidney morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cell-cell signaling involved in kidney development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_kidney_jan10") "Any process that mediates the transfer of information from one cell to another and contributes to the progression of the kidney over time, from its formation to the mature organ.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-01-19T08:33:40Z") +AnnotationAssertion(Annotation( "GOC:mah") "cell-cell signalling involved in kidney development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0060995") +AnnotationAssertion(rdfs:label "cell-cell signaling involved in kidney development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (pattern specification involved in kidney development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_kidney_jan10") "Any developmental process that results in the creation of defined areas or spaces within the kidney to which cells respond and eventually are instructed to differentiate.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-01-21T09:05:54Z") +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "kidney pattern specification") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "kidney pattern formation") +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "pattern formation involved in kidney development") +AnnotationAssertion( "GO:0061004") +AnnotationAssertion(rdfs:label "pattern specification involved in kidney development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cell differentiation involved in kidney development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the kidney as it progresses from its formation to the mature state.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-01-21T09:13:55Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061005") +AnnotationAssertion(rdfs:label "cell differentiation involved in kidney development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of cell proliferation involved in kidney morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_kidney_jan10") "Any process that modulates the frequency, rate or extent of cell proliferation that contributes to the shaping of the kidney.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-01-21T11:25:23Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061006") +AnnotationAssertion(rdfs:label "regulation of cell proliferation involved in kidney morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (hepaticobiliary system process) AnnotationAssertion(Annotation( "GOC:dph") "An system process carried out by any of the organs or tissues of the hepaticobiliary system. The hepaticobiliary system is responsible for metabolic and catabolic processing of small molecules absorbed from the blood or gut, hormones and serum proteins, detoxification, storage of glycogen, triglycerides, metals and lipid soluble vitamins and excretion of bile. Included are the synthesis of albumin, blood coagulation factors, complement, and specific binding proteins.") @@ -40008,6 +100358,176 @@ AnnotationAssertion( "hepaticobiliary system process") SubClassOf( ) +# Class: (hepaticobiliary system development) + +AnnotationAssertion(Annotation( "GOC:dph") "The progression of the hepaticobiliary system over time, from its formation to the mature structure. The hepaticobiliary system is responsible for metabolic and catabolic processing of small molecules absorbed from the blood or gut, hormones and serum proteins, detoxification, storage of glycogen, triglycerides, metals and lipid soluble vitamins and excretion of bile. Included are the synthesis of albumin, blood coagulation factors, complement, and specific binding proteins.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-01-22T09:11:59Z") +AnnotationAssertion(Annotation( "GOC:dph") "hepatobiliary system development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061008") +AnnotationAssertion(rdfs:label "hepaticobiliary system development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (common bile duct development) + +AnnotationAssertion(Annotation( "PMID:20614624") "The progression of the common bile duct over time, from its formation to the mature structure. The common bile duct is formed from the joining of the common hepatic duct running from the liver, and the cystic duct running from the gallbladder. The common bile duct transports bile from the liver and gallbladder to the intestine.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-01-22T09:17:13Z") +AnnotationAssertion(Annotation( "PMID:20614624") "EHBD development") +AnnotationAssertion(Annotation( "PMID:20614624") "extrahepatic bile duct development") +AnnotationAssertion(Annotation( "PMID:20614624") "CBD development") +AnnotationAssertion(Annotation( "GOC:dph") "bile duct development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061009") +AnnotationAssertion(rdfs:label "common bile duct development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (gallbladder development) + +AnnotationAssertion(Annotation( "GOC:dph") "The progression of the gallbladder over time, from its initial formation to the mature structure. The gallbladder is a cavitated organ that stores bile.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-01-22T09:38:44Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061010") +AnnotationAssertion(rdfs:label "gallbladder development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (hepatic duct development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:20614624") "The progression of the hepatic duct over time, from its formation to the mature structure. The hepatic duct is the duct that leads from the liver to the common bile duct.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-01-22T09:44:39Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061011") +AnnotationAssertion(rdfs:label "hepatic duct development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (hepatoblast differentiation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:15226394") "The process in which a relatively unspecialized cell acquires specialized features of a hepatoblast. A hepatoblast is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into hepatocytes and cholangiocytes.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-02-02T09:08:03Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061017") +AnnotationAssertion(rdfs:label "hepatoblast differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (membrane organization) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "A process which results in the assembly, arrangement of constituent parts, or disassembly of a membrane. A membrane is a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.") +AnnotationAssertion( "jl") +AnnotationAssertion( "2010-02-08T02:43:11Z") +AnnotationAssertion( "GO:0016044") +AnnotationAssertion( "GO:0044802") +AnnotationAssertion( "cellular membrane organisation") +AnnotationAssertion( "cellular membrane organization") +AnnotationAssertion(Annotation( "GOC:mah") "membrane organisation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:mah") "membrane organization and biogenesis") +AnnotationAssertion( "single-organism membrane organization") +AnnotationAssertion( "GO:0061024") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "membrane organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (membrane fusion) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "The membrane organization process that joins two lipid bilayers to form a single membrane.") +AnnotationAssertion( "jl") +AnnotationAssertion( "2010-02-08T02:48:06Z") +AnnotationAssertion( "GO:0006944") +AnnotationAssertion( "GO:0044801") +AnnotationAssertion( "Wikipedia:Lipid_bilayer_fusion") +AnnotationAssertion( "cellular membrane fusion") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "single-organism membrane fusion") +AnnotationAssertion( "GO:0061025") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "membrane fusion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (umbilical cord development) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") "The process whose specific outcome is the development of the umbilical cord, from its formation to the mature structure. The umbilical cord is an organ or embryonic origin consisting of the 2 umbilical arteries and the one umbilical vein. The umbilical cord connects the cardiovascular system of the fetus to the mother via the placenta.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-02-09T09:09:22Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061027") +AnnotationAssertion(rdfs:label "umbilical cord development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (eyelid development in camera-type eye) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:yaf") "The progression of the eyelid in a camera-type eye from its formation to the mature state. The eyelid is a membranous cover that helps protect and lubricate the eye.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-02-09T09:36:11Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061029") +AnnotationAssertion(rdfs:label "eyelid development in camera-type eye") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (epithelial cell differentiation involved in mammary gland alveolus development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:yaf") "The process in which a relatively unspecialized epithelial cell becomes a more specialized epithelial cell of the mammary gland alveolus.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-02-09T09:43:00Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061030") +AnnotationAssertion(rdfs:label "epithelial cell differentiation involved in mammary gland alveolus development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (visceral serous pericardium development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:yaf") "The progression of the visceral serous pericardium from its formation to the mature structure. The visceral serous pericardium is the inner layer of the pericardium.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-02-09T09:52:49Z") +AnnotationAssertion(Annotation( "GOC:dph") "epicardium development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061032") +AnnotationAssertion(rdfs:label "visceral serous pericardium development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (olfactory bulb mitral cell layer development) + +AnnotationAssertion(Annotation( "GOC:dph") "The progression of the olfactory bulb mitral cell layer over time from its initial formation until its mature state. The mitral cell layer is composed of pyramidal neurons whose cell bodies are located between the granule cell layer and the plexiform layer.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-02-09T03:30:23Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061034") +AnnotationAssertion(rdfs:label "olfactory bulb mitral cell layer development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (regulation of cartilage development) AnnotationAssertion(Annotation( "GOC:dph") "Any process that modulates the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.") @@ -40016,8 +100536,22 @@ AnnotationAssertion( AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0061035") AnnotationAssertion(rdfs:label "regulation of cartilage development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (positive regulation of cartilage development) + +AnnotationAssertion(Annotation( "GOC:dph") "Any process that increases the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-02-09T03:41:35Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061036") +AnnotationAssertion(rdfs:label "positive regulation of cartilage development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + # Class: (negative regulation of cartilage development) AnnotationAssertion(Annotation( "GOC:dph") "Any process that decreases the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.") @@ -40026,10 +100560,583 @@ AnnotationAssertion( AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0061037") AnnotationAssertion(rdfs:label "negative regulation of cartilage development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ) +# Class: (uterus morphogenesis) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") "The process in which anatomical structures of the uterus are generated and organized.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-02-22T11:12:35Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061038") +AnnotationAssertion(rdfs:label "uterus morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (female gonad morphogenesis) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") "The process in which a female gonad is generated and organized.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-02-22T11:29:28Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "ovary morphogenesis") +AnnotationAssertion( "GO:0061040") +AnnotationAssertion(rdfs:label "female gonad morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (regulation of wound healing) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") "Any process that modulates the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-02-25T10:14:37Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061041") +AnnotationAssertion(rdfs:label "regulation of wound healing") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (negative regulation of wound healing) + +AnnotationAssertion(Annotation( "GOC:dph") "Any process that decreases the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-02-25T10:33:30Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061045") +AnnotationAssertion(rdfs:label "negative regulation of wound healing") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of branching involved in lung morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:yaf") "Any process that modulates the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-02-25T10:41:38Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061046") +AnnotationAssertion(rdfs:label "regulation of branching involved in lung morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of branching involved in lung morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:yaf") "Any process that increases the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-02-25T10:50:01Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061047") +AnnotationAssertion(rdfs:label "positive regulation of branching involved in lung morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of branching involved in lung morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:yaf") "Any process that decreases the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-02-25T10:51:31Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061048") +AnnotationAssertion(rdfs:label "negative regulation of branching involved in lung morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (cell growth involved in cardiac muscle cell development) + +AnnotationAssertion(Annotation( "GOC:dph") "The growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-02-25T12:56:07Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") "cardiac muscle cell hypertrophy") +AnnotationAssertion(Annotation( "GOC:dph") "cardiomyocyte growth") +AnnotationAssertion(Annotation( "GOC:dph") "heart muscle cell growth") +AnnotationAssertion( "GO:0061049") +AnnotationAssertion(rdfs:label "cell growth involved in cardiac muscle cell development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (regulation of cell growth involved in cardiac muscle cell development) + +AnnotationAssertion(Annotation( "GOC:dph") "Any process that modulates the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-02-25T01:05:16Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061050") +AnnotationAssertion(rdfs:label "regulation of cell growth involved in cardiac muscle cell development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (positive regulation of cell growth involved in cardiac muscle cell development) + +AnnotationAssertion(Annotation( "GOC:dph") "Any process that increases the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-02-25T01:08:08Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061051") +AnnotationAssertion(rdfs:label "positive regulation of cell growth involved in cardiac muscle cell development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of cell growth involved in cardiac muscle cell development) + +AnnotationAssertion(Annotation( "GOC:dph") "Any process that decreases the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-02-25T01:11:30Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061052") +AnnotationAssertion(rdfs:label "negative regulation of cell growth involved in cardiac muscle cell development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (somite development) + +AnnotationAssertion(Annotation( "GOC:dph") "The progression of a somite from its initial formation to the mature structure. Somites are mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-03-02T12:05:13Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061053") +AnnotationAssertion(rdfs:label "somite development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (dermatome development) + +AnnotationAssertion(Annotation( "GOC:dph") "The progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-03-02T12:07:37Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061054") +AnnotationAssertion(rdfs:label "dermatome development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (myotome development) + +AnnotationAssertion(Annotation( "GOC:dph") "The progression of the myotome over time, from its formation to the mature structure. The myotome is the portion of the somite that will give rise to muscle.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-03-02T12:11:01Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061055") +AnnotationAssertion(rdfs:label "myotome development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (sclerotome development) + +AnnotationAssertion(Annotation( "GOC:dph") "The progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-03-02T12:12:40Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061056") +AnnotationAssertion(rdfs:label "sclerotome development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (muscle structure development) + +AnnotationAssertion(Annotation( "GOC:dph") "The progression of a muscle structure over time, from its formation to its mature state. Muscle structures are contractile cells, tissues or organs that are found in multicellular organisms.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-03-09T08:55:14Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061061") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "muscle structure development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectAllValuesFrom( )) + +# Class: (regulation of nematode larval development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:kmv") "Any process that modulates the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-03-11T12:59:21Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061062") +AnnotationAssertion(rdfs:label "regulation of nematode larval development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (positive regulation of nematode larval development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:kmv") "Any process that increases the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-03-11T01:03:34Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061063") +AnnotationAssertion(rdfs:label "positive regulation of nematode larval development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of nematode larval development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:kmv") "Any process that decreases the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-03-11T01:04:39Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061064") +AnnotationAssertion(rdfs:label "negative regulation of nematode larval development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (urethra development) + +AnnotationAssertion(Annotation( "GOC:dph") "The progression of the urethra over time from its initial formation to the mature structure. The urethra is a renal system organ that carries urine from the bladder to outside the body.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-03-12T08:24:52Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061068") +AnnotationAssertion(rdfs:label "urethra development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (male urethra development) + +AnnotationAssertion(Annotation( "GOC:dph") "The progression of the male urethra over time from its initial formation to the mature structure. The male urethra is a renal system organ that carries urine from the bladder through the penis to outside the body.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-03-12T08:28:19Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061069") +AnnotationAssertion(rdfs:label "male urethra development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (female urethra development) + +AnnotationAssertion(Annotation( "GOC:dph") "The progression of the female urethra over time from its initial formation to the mature structure. The female urethra is a renal system organ that carries urine from the bladder to outside the body, exiting above the vaginal opening.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-03-12T08:29:43Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061070") +AnnotationAssertion(rdfs:label "female urethra development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (urethra epithelium development) + +AnnotationAssertion(Annotation( "GOC:dph") "The progression of the urethra epithelium over time from its initial formation to the mature structure. The urethra is a renal system organ that carries urine from the bladder to outside the body. The epithelium is the tubular, planar layer of cells through which the urine passes.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-03-12T08:36:53Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061071") +AnnotationAssertion(rdfs:label "urethra epithelium development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (iris morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") "The process in which the iris is generated and organized. The iris is an anatomical structure in the eye whose opening forms the pupil. The iris is responsible for controlling the diameter and size of the pupil and the amount of light reaching the retina.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-03-16T10:48:42Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061072") +AnnotationAssertion(rdfs:label "iris morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (ciliary body morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") "The process in which the ciliary body generated and organized. The ciliary body is the circumferential tissue inside the eye composed of the ciliary muscle and ciliary processes.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-03-16T10:55:19Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061073") +AnnotationAssertion(rdfs:label "ciliary body morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (regulation of neural retina development) + +AnnotationAssertion(Annotation( "GOC:dph") "Any process that modulates the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-03-16T11:47:05Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061074") +AnnotationAssertion(rdfs:label "regulation of neural retina development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of neural retina development) + +AnnotationAssertion(Annotation( "GOC:dph") "Any process that increases the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-03-16T11:59:48Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061075") +AnnotationAssertion(rdfs:label "positive regulation of neural retina development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (negative regulation of neural retina development) + +AnnotationAssertion(Annotation( "GOC:dph") "Any process that decreases the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-03-16T12:46:11Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061076") +AnnotationAssertion(rdfs:label "negative regulation of neural retina development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (left horn of sinus venosus development) + +AnnotationAssertion(Annotation( "GOC:dph") "The progression of the left horn of the sinus venosus from its initial formation to the mature structure.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-04-08T02:40:27Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061079") +AnnotationAssertion(rdfs:label "left horn of sinus venosus development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (right horn of sinus venosus development) + +AnnotationAssertion(Annotation( "GOC:dph") "The progression of the right horn of the sinus venosus from its formation to the mature structure.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-04-08T02:45:10Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061080") +AnnotationAssertion(rdfs:label "right horn of sinus venosus development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (positive regulation of myeloid leukocyte cytokine production involved in immune response) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") "Any process that modulates the rate, frequency, or extent of the production of a cytokine that contributes to the immune response.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-04-13T11:26:41Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") "positive regulation of myeloid cell cytokine production involved in immune response") +AnnotationAssertion( "GO:0061081") +AnnotationAssertion(rdfs:label "positive regulation of myeloid leukocyte cytokine production involved in immune response") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (myeloid leukocyte cytokine production) + +AnnotationAssertion(Annotation( "GOC:dph") "Any process that contributes to cytokine production by a myeloid cell.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-04-13T11:29:42Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061082") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.") +AnnotationAssertion(rdfs:label "myeloid leukocyte cytokine production") +SubClassOf( ) + +# Class: (regulation of protein tyrosine kinase activity) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the rate, frequency, or extent of protein tyrosine kinase activity.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-04-26T02:34:53Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061097") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "regulation of protein tyrosine kinase activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (positive regulation of protein tyrosine kinase activity) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that increases the rate, frequency, or extent of protein tyrosine kinase activity.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-04-26T02:34:53Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061098") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "positive regulation of protein tyrosine kinase activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (negative regulation of protein tyrosine kinase activity) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that decreases the rate, frequency, or extent of protein tyrosine kinase activity.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-04-26T02:34:53Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061099") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "negative regulation of protein tyrosine kinase activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (lung neuroendocrine cell differentiation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:9126746") "The process in which a relatively unspecialized cell acquires specialized features of a neuroendocrine cell of the lung epithelium.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-04-27T03:28:46Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061100") +AnnotationAssertion(rdfs:label "lung neuroendocrine cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (neuroendocrine cell differentiation) + +AnnotationAssertion(Annotation( "GOC:dph") "The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a neuroendocrine cell. A neuroendocrine cell is a cell that receives input form a neuron which controls the secretion of an endocrine substance.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-04-28T09:42:20Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061101") +AnnotationAssertion(rdfs:label "neuroendocrine cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (stomach neuroendocrine cell differentiation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:18173746") "The process in which a relatively unspecialized cell acquires specialized features of a neuroendocrine cell of the stomach epithelium.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-04-28T09:47:07Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") "gastric neuroendocrine cell differentiation") +AnnotationAssertion( "GO:0061102") +AnnotationAssertion(rdfs:label "stomach neuroendocrine cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (adrenal chromaffin cell differentiation) + +AnnotationAssertion(Annotation( "GOC:dph") "The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of an adrenal chromaffin cell. An adrenal chromaffin cell is a neuroendocrine cell that stores epinephrine secretory vesicles.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-04-29T08:27:53Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061104") +AnnotationAssertion(rdfs:label "adrenal chromaffin cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (regulation of stomach neuroendocrine cell differentiation) + +AnnotationAssertion(Annotation( "GOC:dph") "Any process that modulates the rate, frequency or extent of the differentiation of a neuroendocrine cell in the stomach.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-04-29T12:19:37Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061105") +AnnotationAssertion(rdfs:label "regulation of stomach neuroendocrine cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of stomach neuroendocrine cell differentiation) + +AnnotationAssertion(Annotation( "GOC:dph") "Any process that decreases the rate, frequency or extent of the differentiation of a neuroendocrine cell in the stomach.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-04-29T12:23:05Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061106") +AnnotationAssertion(rdfs:label "negative regulation of stomach neuroendocrine cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (seminal vesicle development) + +AnnotationAssertion(Annotation( "GOC:dph") "The progression of the seminal vesicle over time, from its formation to the mature structure. The seminal vesicle is a gland that contributes to the production of semen.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-04-30T10:17:30Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061107") +AnnotationAssertion(rdfs:label "seminal vesicle development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (seminal vesicle epithelium development) + +AnnotationAssertion(Annotation( "GOC:dph") "The progression of the seminal vesicle epithelium over time, from its formation to the mature structure.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-04-30T10:19:54Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061108") +AnnotationAssertion(rdfs:label "seminal vesicle epithelium development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (dense core granule organization) + +AnnotationAssertion(Annotation( "GOC:dph") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a dense core granule. A dense core granule is a secretory organelle found in endocrine cells.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-05-01T09:34:37Z") +AnnotationAssertion(Annotation( "GOC:mah") "dense core granule organisation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061109") +AnnotationAssertion(rdfs:label "dense core granule organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (pancreas morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") "Morphogenesis of the pancreas. Morphogenesis is the process in which anatomical structures are generated and organized.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-05-05T11:55:30Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061113") +AnnotationAssertion(rdfs:label "pancreas morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (branching involved in pancreas morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") "The process in which the branches of the pancreas are generated and organized.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-05-05T12:03:04Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061114") +AnnotationAssertion(rdfs:label "branching involved in pancreas morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of heart growth) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:hjd") "Any process that decreases the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-05-17T07:31:28Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061117") +AnnotationAssertion(rdfs:label "negative regulation of heart growth") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (pancreatic bud formation) + +AnnotationAssertion(Annotation( "GOC:dph") "The morphogenetic process in which the foregut region specified to become the pancreas forms a bud.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-05-17T09:33:40Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061130") +AnnotationAssertion(rdfs:label "pancreatic bud formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + # Class: (morphogenesis of a branching epithelium) AnnotationAssertion(Annotation( "GOC:dph") "The process in which the anatomical structures of a branched epithelium are generated and organized.") @@ -40041,6 +101148,1536 @@ AnnotationAssertion(rdfs:label "morp SubClassOf( ) SubClassOf( ) +# Class: (lung secretory cell differentiation) + +AnnotationAssertion(Annotation( "GOC:dph") "The process in which a relatively unspecialized cell acquires specialized features of a lung secretory cell. A lung secretory cell is a specialized epithelial cell of the lung that contains large secretory granules in its apical part.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-05-25T09:28:53Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061140") +AnnotationAssertion(rdfs:label "lung secretory cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (lung ciliated cell differentiation) + +AnnotationAssertion(Annotation( "GOC:cilia") Annotation( "GOC:dph") Annotation( "GOC:krc") "The process in which a relatively unspecialized cell acquires specialized features of a lung ciliated cell. A lung ciliated cell is a specialized lung epithelial cell that contains cilia for moving substances released from lung secretory cells.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-05-25T09:31:14Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061141") +AnnotationAssertion(rdfs:label "lung ciliated cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (alveolar primary septum development) + +AnnotationAssertion(Annotation( "GOC:dph") "The progression of a primary alveolar septum over time, from its formation to the mature structure. A primary alveolar septum is a specialized epithelium that surrounds the saccule as it forms.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-05-25T10:21:27Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061143") +AnnotationAssertion(rdfs:label "alveolar primary septum development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (alveolar secondary septum development) + +AnnotationAssertion(Annotation( "GOC:dph") "The progression of a secondary alveolar septum over time, from its formation to the mature structure. A secondary alveolar septum is a specialized epithelium that subdivides the initial saccule.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-05-25T10:43:55Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061144") +AnnotationAssertion(rdfs:label "alveolar secondary septum development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (Peyer's patch morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") "The process in which a Peyer's patch is generated and organized. Peyer's patches are typically found as nodules associated with gut epithelium with distinct internal structures including B- and T-zones for the activation of lymphocytes.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-05-26T06:46:23Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061146") +AnnotationAssertion(rdfs:label "Peyer's patch morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (endocardial endothelium development) + +AnnotationAssertion(Annotation( "GOC:dph") "The progression of the endocardial endothelium over time, from its initial formation to the mature structure. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-06-03T09:15:31Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061147") +AnnotationAssertion(rdfs:label "endocardial endothelium development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (extracellular matrix organization involved in endocardium development) + +AnnotationAssertion(Annotation( "GOC:dph") "A process which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix of the endocardium. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-06-03T09:18:02Z") +AnnotationAssertion(Annotation( "GOC:mah") "extracellular matrix organisation involved in endocardium development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061148") +AnnotationAssertion(rdfs:label "extracellular matrix organization involved in endocardium development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (trachea submucosa development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:yaf") "The progression of the trachea submucosa over time from its formation to the mature structure. The trachea submucosa is made up of the glands and elastic tissue that lie under the mucosa in the trachea.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-06-07T09:58:40Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061152") +AnnotationAssertion(rdfs:label "trachea submucosa development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (trachea gland development) + +AnnotationAssertion(Annotation( "GOC:dph") "The progression of a trachea gland over time, from its formation to the mature structure. Trachea glands are found under the mucus of the trachea and secrete mucus, and agents that help protect the lung from injury and infection.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-06-07T10:10:51Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061153") +AnnotationAssertion(rdfs:label "trachea gland development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (endothelial tube morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:yaf") "The process in which the anatomical structures of a tube are generated and organized from an endothelium. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-06-15T09:05:00Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061154") +AnnotationAssertion(rdfs:label "endothelial tube morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (pulmonary artery endothelial tube morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:yaf") "The process in which the anatomical structures of a tube are generated and organized from the pulmonary artery endothelium. An pulmonary artery endothelium is an epithelium that lines the pulmonary artery.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-06-15T09:09:04Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061155") +AnnotationAssertion(rdfs:label "pulmonary artery endothelial tube morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (pulmonary artery morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:yaf") "The process in which the anatomical structures of the pulmonary artery are generated and organized. The pulmonary artery is the artery that carries blood from the heart to the lungs.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-06-15T09:13:47Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061156") +AnnotationAssertion(rdfs:label "pulmonary artery morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of hair follicle placode formation) + +AnnotationAssertion(Annotation( "GOC:dph") "Any process that modulates the rate, frequency, or extent of hair follicle placode formation, the developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-06-25T01:03:29Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061168") +AnnotationAssertion(rdfs:label "regulation of hair follicle placode formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (positive regulation of hair placode formation) + +AnnotationAssertion(Annotation( "GOC:dph") "Any process that increases the rate, frequency, or extent of hair follicle placode formation, the developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-06-25T01:08:50Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061169") +AnnotationAssertion(rdfs:label "positive regulation of hair placode formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of hair follicle placode formation) + +AnnotationAssertion(Annotation( "GOC:dph") "Any process that decreases the rate, frequency, or extent of hair follicle placode formation, the developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-06-25T01:10:48Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061170") +AnnotationAssertion(rdfs:label "negative regulation of hair follicle placode formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (regulation of insulin secretion involved in cellular response to glucose stimulus) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") "Any process that modulates the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-07-13T09:38:42Z") +AnnotationAssertion(Annotation( "GOC:dph") "regulation of insulin secretion in response to glucose") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061178") +AnnotationAssertion(rdfs:label "regulation of insulin secretion involved in cellular response to glucose stimulus") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (negative regulation of insulin secretion involved in cellular response to glucose stimulus) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") "Any process that decreases the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-07-13T09:41:46Z") +AnnotationAssertion(Annotation( "GOC:bf") "negative regulation of insulin secretion involved in cellular response to glucose") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") "negative regulation of insulin secretion in response to glucose") +AnnotationAssertion( "GO:0061179") +AnnotationAssertion(rdfs:label "negative regulation of insulin secretion involved in cellular response to glucose stimulus") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (mammary gland epithelium development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:yaf") "The process whose specific outcome is the progression of the mammary gland epithelium over time, from its formation to the mature structure. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-07-14T08:18:24Z") +AnnotationAssertion(Annotation( "GOC:dph") "breast epithelium development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061180") +AnnotationAssertion(rdfs:label "mammary gland epithelium development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (regulation of chondrocyte development) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") "Any process that modulates the rate, frequency, or extent of the process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-07-14T08:28:52Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061181") +AnnotationAssertion(rdfs:label "regulation of chondrocyte development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of chondrocyte development) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") "Any process that decreases the rate, frequency, or extent of the process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-07-14T08:33:05Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061182") +AnnotationAssertion(rdfs:label "negative regulation of chondrocyte development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of dermatome development) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") "Any process that modulates the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-07-14T08:40:26Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061183") +AnnotationAssertion(rdfs:label "regulation of dermatome development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of dermatome development) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") "Any process that increases the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-07-14T08:42:03Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061184") +AnnotationAssertion(rdfs:label "positive regulation of dermatome development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (negative regulation of dermatome development) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") "Any process that decreases the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-07-14T08:43:08Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061185") +AnnotationAssertion(rdfs:label "negative regulation of dermatome development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (positive regulation of sclerotome development) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") "Any process that increases the rate, frequency, or extent of the progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-07-14T09:17:23Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061189") +AnnotationAssertion(rdfs:label "positive regulation of sclerotome development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of sclerotome development) + +AnnotationAssertion(Annotation( "GOC:dph") "Any process that modulates the rate, frequency, or extent of the progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-07-14T09:19:47Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061190") +AnnotationAssertion(rdfs:label "regulation of sclerotome development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (taste bud development) + +AnnotationAssertion(Annotation( "GOC:dph") "The progression of the taste bud over time, from its formation to the mature state. The taste bud is a specialized area of the tongue that contains taste receptors.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-07-27T10:55:08Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061193") +AnnotationAssertion(rdfs:label "taste bud development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (taste bud morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") "The process in which the anatomical structures of the taste bud are generated and organized. The taste bud is a specialized area of the tongue that contains taste receptors.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-07-27T11:01:31Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061194") +AnnotationAssertion(rdfs:label "taste bud morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (taste bud formation) + +AnnotationAssertion(Annotation( "GOC:dph") "The developmental process pertaining to the initial formation of the taste bud from unspecified parts. The taste bud is a specialized area of the tongue that contains taste receptors.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-07-27T12:22:26Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061195") +AnnotationAssertion(rdfs:label "taste bud formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (fungiform papilla development) + +AnnotationAssertion(Annotation( "GOC:dph") "The progression of the fungiform papilla over time, from its formation to the mature structure. The fungiform papilla is a mushroom-shaped papilla of the tongue.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-07-27T12:23:48Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061196") +AnnotationAssertion(rdfs:label "fungiform papilla development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (fungiform papilla morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") "The process in which the anatomical structures of the fungiform papilla are generated and organized. The fungiform papilla is a mushroom-shaped papilla of the tongue.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-07-27T12:26:40Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061197") +AnnotationAssertion(rdfs:label "fungiform papilla morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (fungiform papilla formation) + +AnnotationAssertion(Annotation( "GOC:dph") "The developmental process pertaining to the initial formation of a spongiform papilla from unspecified parts. The fungiform papilla is a mushroom-shaped papilla of the tongue.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-07-27T12:29:03Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061198") +AnnotationAssertion(rdfs:label "fungiform papilla formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (paramesonephric duct development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:yaf") "The process whose specific outcome is the progression of the paramesonephric duct over time, from its formation to the mature structure. Mullerian ducts (or paramesonephric ducts) are paired ducts of the embryo that run down the lateral sides of the urogenital ridge and terminate at the mullerian eminence in the primitive urogenital sinus. In the female, they will develop to form the fallopian tubes, uterus, cervix, and the upper portion of the vagina; in the male, they are lost. These ducts are made of tissue of mesodermal origin.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-07-30T10:54:47Z") +AnnotationAssertion(Annotation( "GOC:dph") "Mullerian duct development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061205") +AnnotationAssertion(rdfs:label "paramesonephric duct development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (mesonephros morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the anatomical structures of the mesonephros are generated and organized.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-08-17T03:11:10Z") +AnnotationAssertion(Annotation( "GOC:dph") "Wolffian body morphogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061206") +AnnotationAssertion(rdfs:label "mesonephros morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cell differentiation involved in mesonephros development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the mesonephros as it progresses from its formation to the mature state.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-08-17T03:21:23Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061208") +AnnotationAssertion(rdfs:label "cell differentiation involved in mesonephros development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (cell proliferation involved in mesonephros development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The multiplication or reproduction of cells, resulting in the expansion of the population in the mesonephros.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-08-17T03:22:46Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061209") +AnnotationAssertion(rdfs:label "cell proliferation involved in mesonephros development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (cell-cell signaling involved in mesonephros development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "Any process that mediates the transfer of information from one cell to another and contributes to the progression of the mesonephros over time, from its formation to the mature organ.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-08-17T03:24:08Z") +AnnotationAssertion(Annotation( "GOC:mah") "cell-cell signalling involved in mesonephros development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061210") +AnnotationAssertion(rdfs:label "cell-cell signaling involved in mesonephros development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (mesonephric collecting duct development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of a collecting duct in the mesonephros over time, from its formation to the mature structure. The collecting duct regulates water, electrolyte and acid-base balance. The collecting duct is the final common path through which urine flows before entering the ureter and then emptying into the bladder.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-08-17T03:25:51Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061211") +AnnotationAssertion(rdfs:label "mesonephric collecting duct development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (mesonephric juxtaglomerular apparatus development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the juxtaglomerular apparatus in the mesonephros over time, from its formation to the mature structure. The juxtaglomerular apparatus is an anatomical structure which consists of juxtaglomerular cells, extraglomerular mesangial cells and the macula densa. The juxtaglomerular apparatus lies adjacent to the glomerulus and regulates kidney function by maintaining the blood flow to the kidney and the filtration rate.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-08-17T03:27:36Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061212") +AnnotationAssertion(rdfs:label "mesonephric juxtaglomerular apparatus development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (positive regulation of mesonephros development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "Any process that increases the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-08-17T03:39:35Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061213") +AnnotationAssertion(rdfs:label "positive regulation of mesonephros development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (mesonephric smooth muscle tissue development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of smooth muscle in the mesonephros over time, from its formation to the mature structure.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-08-17T03:29:54Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061214") +AnnotationAssertion(rdfs:label "mesonephric smooth muscle tissue development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (mesonephric nephron development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of a nephron in the mesonephros over time, from its formation to the mature structure. A nephron is the functional unit of the kidney.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-08-17T03:31:08Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061215") +AnnotationAssertion(rdfs:label "mesonephric nephron development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (regulation of mesonephros development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "Any process that modulates the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-08-17T03:35:31Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061217") +AnnotationAssertion(rdfs:label "regulation of mesonephros development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of mesonephros development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "Any process that decreases the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-08-17T03:43:06Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061218") +AnnotationAssertion(rdfs:label "negative regulation of mesonephros development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (mesonephric mesenchyme development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The biological process whose specific outcome is the progression of a mesonephric mesenchyme from an initial condition to its mature state. This process begins with the formation of mesonephric mesenchyme and ends with the mature structure. Mesonephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the mesonephros.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-08-17T03:45:44Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061219") +AnnotationAssertion(rdfs:label "mesonephric mesenchyme development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (mesonephric macula densa development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the mesonephric macula densa over time, from its formation to the mature structure. The mesonephric macula densa is an area of specialized cells in the distal tubule of the mesonephros that makes contact with the vascular pole of the glomerulus.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-08-19T01:11:41Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061220") +AnnotationAssertion(rdfs:label "mesonephric macula densa development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (mesonephric mesenchyme morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the anatomical structures of a mesonephric mesenchymal tissue are generated and organized. Mesonephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the mesonephros.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-08-19T01:17:38Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061221") +AnnotationAssertion(rdfs:label "mesonephric mesenchyme morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (mesonephric glomerulus development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The progression of the mesonephric glomerulus over time from its initial formation until its mature state. The mesonephric glomerulus is a capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the mature vertebrate kidney, or mesonephros.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-08-19T01:26:00Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061224") +AnnotationAssertion(rdfs:label "mesonephric glomerulus development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (pattern specification involved in mesonephros development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "Any developmental process that results in the creation of defined areas or spaces within the mesonephros to which cells respond and eventually are instructed to differentiate.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-08-19T02:22:22Z") +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "mesonephros pattern specification") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "mesonephros pattern formation") +AnnotationAssertion( "GO:0061227") +AnnotationAssertion(rdfs:label "pattern specification involved in mesonephros development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (mesonephric nephron morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the anatomical structures of the mesonephric nephron are generated and organized. A mesonephric nephron is the functional unit of the mesonephros.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-08-19T02:26:24Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061228") +AnnotationAssertion(rdfs:label "mesonephric nephron morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (mesonephric glomerulus vasculature development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The biological process whose specific outcome is the progression of a mesonephric glomerulus vasculature from an initial condition to its mature state. This process begins with the formation of the mesonephric glomerulus vasculature and ends with the mature structure. The mesonephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the mesonephric glomerulus.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-08-19T02:47:06Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061231") +AnnotationAssertion(rdfs:label "mesonephric glomerulus vasculature development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (mesonephric glomerular epithelium development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the mesonephric glomerular epithelium over time, from its formation to the mature structure. The mesonephric glomerular epithelium is an epithelial tissue that covers the outer surfaces of the glomerulus in the mesonephros. The mesonephric glomerular epithelium consists of both parietal and visceral epithelium. Mesonephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the mesonephros.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-08-19T02:49:46Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061232") +AnnotationAssertion(rdfs:label "mesonephric glomerular epithelium development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (mesonephric glomerulus morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the anatomical structures of the mesonephric glomerulus are generated and organized. The mesonephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate mesonephros.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-08-19T02:53:35Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061234") +AnnotationAssertion(rdfs:label "mesonephric glomerulus morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which an organism retains a population of mesenchymal stem cells that contributes to the shaping of a nephron in the mesonephros. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-08-19T02:57:11Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061235") +AnnotationAssertion(rdfs:label "mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (mesonephric comma-shaped body morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the mesonephric comma-shaped body is generated and organized. The mesonephric comma-shaped body is the precursor structure to the mesonephric S-shaped body that contributes to the morphogenesis of a nephron in the mesonephros.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-08-19T03:00:21Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061236") +AnnotationAssertion(rdfs:label "mesonephric comma-shaped body morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (mesonephric nephron tubule morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the anatomical structures of a mesonephric nephron tubule are generated and organized. A mesonephric nephron tubule is an epithelial tube that is part of the mesonephric nephron, the functional part of the mesonephros.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-08-19T03:09:26Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061240") +AnnotationAssertion(rdfs:label "mesonephric nephron tubule morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (mesonephric nephron epithelium development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the mesonephric nephron epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The mesonephric nephron epithelium is a tissue that covers the surface of a nephron in the mesonephros.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-08-19T03:11:59Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061241") +AnnotationAssertion(rdfs:label "mesonephric nephron epithelium development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (mesonephric nephron tubule development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The progression of a mesonephric nephron tubule over time, from its initial formation to the mature structure. A mesonephric nephron tubule is an epithelial tube that is part of the mesonephric nephron, the functional part of the mesonephros.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-08-19T03:17:00Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061242") +AnnotationAssertion(rdfs:label "mesonephric nephron tubule development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (mesonephric renal vesicle morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the anatomical structures of the mesonephric renal vesicle are generated and organized. The renal vesicle is the primordial structure of the mesonephric nephron epithelium, and is formed by the condensation of mesenchymal cells.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-08-19T03:20:21Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061243") +AnnotationAssertion(rdfs:label "mesonephric renal vesicle morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (mesonephric S-shaped body morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the mesonephric S-shaped body is generated and organized. The mesonephric S-shaped body is the successor of the mesonephric comma-shaped body that contributes to the morphogenesis of a nephron in the mesonephros.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-08-19T03:23:55Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061244") +AnnotationAssertion(rdfs:label "mesonephric S-shaped body morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (mesonephric glomerular mesangium development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the mesonephric glomerular mesangium over time, from its formation to the mature structure. The mesonephric glomerular mesangium is the thin membrane connective tissue composed of mesangial cells in the mesonephros, which helps to support the capillary loops in a renal glomerulus.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-08-30T12:59:25Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061247") +AnnotationAssertion(rdfs:label "mesonephric glomerular mesangium development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (mesonephric glomerulus vasculature morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the anatomical structures of the mesonephric glomerulus vasculature are generated and organized. The mesonephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the mesonephric glomerulus.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-08-30T01:11:34Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061248") +AnnotationAssertion(rdfs:label "mesonephric glomerulus vasculature morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (mesonephric glomerular capillary formation) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process that gives rise to a mesonephric glomerular capillary. This process pertains to the initial formation of a structure from unspecified parts.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-08-30T01:17:08Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061249") +AnnotationAssertion(rdfs:label "mesonephric glomerular capillary formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (mesonephric glomerular epithelial cell differentiation) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which a relatively unspecialized cell acquires specialized features of a mesonephric glomerular epithelial cell. Mesonephric glomerular epithelial cells are specialized epithelial cells that form part of the mesonephric glomerulus; there are two types, mesonephric glomerular parietal epithelial cells and mesonephric glomerular visceral epithelial cells.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-08-30T01:20:03Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061250") +AnnotationAssertion(rdfs:label "mesonephric glomerular epithelial cell differentiation") +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (mesonephric glomerular epithelial cell development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of a mesonephric glomerular epithelial cell over time, from its formation to the mature structure. Mesonephric glomerular epithelial cells are specialized epithelial cells that form part of the mesonephric glomerulus; there are two types, mesonephric glomerular parietal epithelial cells and mesonephric glomerular visceral epithelial cells.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-08-30T01:20:45Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061251") +AnnotationAssertion(rdfs:label "mesonephric glomerular epithelial cell development") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (mesonephric podocyte differentiation) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which a relatively unspecialized cell acquires specialized features of a mesonephric glomerular visceral epithelial cell. A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the mesonephros.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/23000"^^xsd:anyURI) +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-08-30T02:03:38Z") +AnnotationAssertion( "mesonephric glomerular visceral epithelial cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061256") +AnnotationAssertion(rdfs:label "mesonephric podocyte differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (mesonephric podocyte development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of a mesonephric glomerular visceral epithelial cell over time, from its formation to the mature structure. A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the mesonephros.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/23000"^^xsd:anyURI) +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-08-30T02:10:40Z") +AnnotationAssertion( "mesonephric glomerular visceral epithelial cell development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061257") +AnnotationAssertion(rdfs:label "mesonephric podocyte development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (mesenchymal to epithelial transition involved in mesonephros morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "A transition where a mesenchymal cell establishes apical/basolateral polarity, forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the mesonephros.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-08-30T02:35:15Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "mesonephric mesenchyme to epithelial transition") +AnnotationAssertion( "GO:0061261") +AnnotationAssertion(rdfs:label "mesenchymal to epithelial transition involved in mesonephros morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (mesonephric renal vesicle formation) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The developmental process pertaining to the initial formation of the mesonephros.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-08-30T02:41:20Z") +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "mesonephros formation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061262") +AnnotationAssertion(rdfs:label "mesonephric renal vesicle formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (mesonephric nephron tubule epithelial cell differentiation) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the mesonephric nephron tubule as it progresses from its formation to the mature state.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-08-30T03:02:09Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061265") +AnnotationAssertion(rdfs:label "mesonephric nephron tubule epithelial cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (mesenchymal to epithelial transition involved in mesonephric renal vesicle formation) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the mesonephric renal vesicle.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-08-30T03:26:30Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061271") +AnnotationAssertion(rdfs:label "mesenchymal to epithelial transition involved in mesonephric renal vesicle formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (mesonephric connecting tubule development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the mesonephric connecting tubule over time, from its formation to the mature structure. The mesonephric connecting tubule is a tubular segment of the mesonephric nephron; it connects the distal tubule to the collecting duct in the mesonephros.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-09-02T12:00:56Z") +AnnotationAssertion(Annotation( "GOC:dph") "mesonephric collecting tubule development") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "mesonephric connecting duct development") +AnnotationAssertion( "GO:0061272") +AnnotationAssertion(rdfs:label "mesonephric connecting tubule development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (mesonephric distal tubule morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the anatomical structures of a mesonephric distal tubule are generated and organized. The mesonephric distal tubule is a mesonephric nephron tubule that begins at the macula densa and extends to the mesonephric connecting tubule.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-09-02T12:12:00Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061273") +AnnotationAssertion(rdfs:label "mesonephric distal tubule morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (mesonephric distal tubule development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the mesonephric distal tubule over time, from its formation to the mature structure. The mesonephric distal tubule is a mesonephric nephron tubule that begins at the terminal segment of the proximal tubule and ends at the mesonephric connecting tubule.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-09-02T12:16:25Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061274") +AnnotationAssertion(rdfs:label "mesonephric distal tubule development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (mesonephric proximal tubule development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The progression of the mesonephric proximal tubule over time, from its formation to the mature structure. The mesonephric proximal tubule extends from the capsule to the distal tubule.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-09-02T01:08:05Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061275") +AnnotationAssertion(rdfs:label "mesonephric proximal tubule development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (mesonephric proximal tubule morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the anatomical structures of a mesonephric proximal tubule are generated and organized. The mesonephric proximal tubule extends from the capsule to the distal tubule.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-09-02T01:11:02Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061276") +AnnotationAssertion(rdfs:label "mesonephric proximal tubule morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (mesonephric nephron tubule formation) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The developmental process pertaining to the initial formation of a mesonephric nephron tubule from unspecified parts. A mesonephric nephron tubule is an epithelial tube that is part of a nephron in the mesonephros.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-09-02T01:16:21Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061277") +AnnotationAssertion(rdfs:label "mesonephric nephron tubule formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (epithelial cell migration involved in mesonephric nephron tubule morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The orderly movement of epithelial cells within a renal tubule that contributes to mesonephric nephron tubule morphogenesis.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-09-02T01:18:53Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061278") +AnnotationAssertion(rdfs:label "epithelial cell migration involved in mesonephric nephron tubule morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (epithelial cell migration involved in mesonephric distal tubule morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The orderly movement of epithelial cells within a renal tubule that contributes to mesonephric distal tubule morphogenesis.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-09-02T01:20:56Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061279") +AnnotationAssertion(rdfs:label "epithelial cell migration involved in mesonephric distal tubule morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (epithelial cell migration involved in mesonephric proximal tubule morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The orderly movement of epithelial cells within a renal tubule that contributes to mesonephric proximal tubule morphogenesis.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-09-02T01:23:43Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061280") +AnnotationAssertion(rdfs:label "epithelial cell migration involved in mesonephric proximal tubule morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (mesonephric capsule development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The progression of the mesonephric capsule over time, from its formation to the mature structure. The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-09-02T01:50:06Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061285") +AnnotationAssertion(rdfs:label "mesonephric capsule development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (mesonephric capsule morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the anatomical structures of the mesonephric capsule are generated and organized. The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-09-02T01:53:31Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061286") +AnnotationAssertion(rdfs:label "mesonephric capsule morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (mesonephric capsule formation) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The developmental process pertaining to the initial formation of a mesonephric capsule from unspecified parts. The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-09-02T01:55:03Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061287") +AnnotationAssertion(rdfs:label "mesonephric capsule formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:mtg_kidney_jan10") "Any process that modulates the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the mesonephros.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-09-06T09:48:56Z") +AnnotationAssertion( "regulation of mesenchymal stem cell apoptotic process involved in mesonephric nephron morphogenesis") +AnnotationAssertion( "regulation of mesenchymal stem cell apoptosis involved in mesonephric nephron morphogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061295") +AnnotationAssertion(rdfs:label "regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:mtg_kidney_jan10") "Any process that reduces the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the mesonephros.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-09-06T09:54:49Z") +AnnotationAssertion( "negative regulation of mesenchymal stem cell apoptotic process involved in mesonephric nephron morphogenesis") +AnnotationAssertion( "negative regulation of mesenchymal stem cell apoptosis involved in mesonephric nephron morphogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061296") +AnnotationAssertion(rdfs:label "negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (positive regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:mtg_kidney_jan10") "Any process that increases the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the mesonephros.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-09-06T09:58:59Z") +AnnotationAssertion( "positive regulation of mesenchymal stem cell apoptotic process involved in mesonephric nephron morphogenesis") +AnnotationAssertion( "positive regulation of mesenchymal stem cell apoptosis involved in mesonephric nephron morphogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061297") +AnnotationAssertion(rdfs:label "positive regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (retina vasculature development in camera-type eye) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") "The process whose specific outcome is the progression of the vasculature of the retina over time, from its formation to the mature structure.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-09-06T03:27:06Z") +AnnotationAssertion(Annotation( "GOC:dph") "retinal vasculature development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061298") +AnnotationAssertion(rdfs:label "retina vasculature development in camera-type eye") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (retina vasculature morphogenesis in camera-type eye) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") "The process in which the vasculature of the retina is generated and organized.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-09-06T03:28:25Z") +AnnotationAssertion(Annotation( "GOC:dph") "retinal vasculature morphogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061299") +AnnotationAssertion(rdfs:label "retina vasculature morphogenesis in camera-type eye") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cerebellum vasculature development) + +AnnotationAssertion(Annotation( "GOC:dph") "The process whose specific outcome is the progression of the vasculature of the cerebellum over time, from its formation to the mature structure.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-09-06T03:36:40Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061300") +AnnotationAssertion(rdfs:label "cerebellum vasculature development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (cerebellum vasculature morphogenesis) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") "The process in which the vasculature of the cerebellum is generated and organized.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-09-06T03:38:05Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061301") +AnnotationAssertion(rdfs:label "cerebellum vasculature morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cornea development in camera-type eye) + +AnnotationAssertion(Annotation( "GOC:dph") "The progression of the cornea over time, from its formation to the mature structure. The cornea is the transparent structure that covers the anterior of the eye.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-09-14T02:09:08Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061303") +AnnotationAssertion(rdfs:label "cornea development in camera-type eye") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (retinal blood vessel morphogenesis) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") "The process whose specific outcome is the progression of a blood vessel of the retina over time, from its formation to the mature structure.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-09-16T09:02:59Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061304") +AnnotationAssertion(rdfs:label "retinal blood vessel morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (cardiac neural crest cell differentiation involved in heart development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_heart") Annotation( "PMID:19705442") "The process in which a relatively unspecialized cell acquires specialized features of a cardiac neural crest cell that will migrate to the heart and contribute to its development. Cardiac neural crest cells are specialized cells that migrate toward the heart from the third, fourth and sixth pharyngeal arches.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-09-23T08:50:56Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061307") +AnnotationAssertion(rdfs:label "cardiac neural crest cell differentiation involved in heart development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (cardiac neural crest cell development involved in heart development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_heart") "The process aimed at the progression of a cardiac neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell that contributes to the development of the heart.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-09-23T09:01:49Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061308") +AnnotationAssertion(rdfs:label "cardiac neural crest cell development involved in heart development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cardiac neural crest cell development involved in outflow tract morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_heart") "The process aimed at the progression of a cardiac neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell that contributes to the shaping of the outflow tract.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-09-23T09:08:37Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061309") +AnnotationAssertion(rdfs:label "cardiac neural crest cell development involved in outflow tract morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (cell surface receptor signaling pathway involved in heart development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_heart") Annotation( "GOC:signaling") "The series of molecular signals initiated by a ligand the binding to its receptor on the surface of a cell, which contributes to the progression of the heart over time.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-09-23T09:18:32Z") +AnnotationAssertion(Annotation( "GOC:bf") "cell surface receptor linked signaling pathway involved in heart development") +AnnotationAssertion(Annotation( "GOC:mah") "cell surface receptor linked signalling pathway involved in heart development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061311") +AnnotationAssertion(rdfs:label "cell surface receptor signaling pathway involved in heart development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (renal filtration cell differentiation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_kidney_jan10") "The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a renal filtration cell. Renal filtration cells are specialized cells of the renal system that filter fluids by charge, size or both. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-09-24T12:18:35Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061318") +AnnotationAssertion(rdfs:label "renal filtration cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cell proliferation involved in heart morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_heart") "The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to the shaping of the heart.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-09-28T09:05:26Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061323") +AnnotationAssertion(rdfs:label "cell proliferation involved in heart morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (cell proliferation involved in outflow tract morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_heart") "The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to the shaping of the outflow tract.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-09-28T09:29:30Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061325") +AnnotationAssertion(rdfs:label "cell proliferation involved in outflow tract morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (renal tubule development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_kidney_jan10") "The progression of the renal tubule over time from its formation to the mature form. A renal tubule is a tube that filters, re-absorbs and secretes substances to rid an organism of waste and to play a role in fluid homeostasis.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-09-28T12:50:43Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061326") +AnnotationAssertion(rdfs:label "renal tubule development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (epithelial cell proliferation involved in Malpighian tubule morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_kidney_jan10") Annotation( "PMID:19783135") "The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population and contributing to the shaping of a Malpighian tubule.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-09-28T02:01:02Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061331") +AnnotationAssertion(rdfs:label "epithelial cell proliferation involved in Malpighian tubule morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (Malpighian tubule bud morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_kidney_jan10") Annotation( "PMID:19783135") "The morphogenetic process in which a bud forms from the embryonic hindgut tube to form the Malpighian tubule. A bud is a protrusion that forms from the tube by localized changes in cell shape and position.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-09-28T01:39:32Z") +AnnotationAssertion(Annotation( "GOC:dph") "Malpighian tubule formation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061332") +AnnotationAssertion(rdfs:label "Malpighian tubule bud morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (renal tubule morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_kidney_jan10") "The process in which the renal tubule is generated by specification of cell fate, through the maintenance of cell polarity, regulated cell proliferation and morphogenetic cell rearrangements, shape changes and growth. A renal tubule is a tube that filters, re-absorbs and secretes substances to rid an organism of waste and to play a role in fluid homeostasis.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-09-28T01:43:04Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061333") +AnnotationAssertion(rdfs:label "renal tubule morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cell rearrangement involved in Malpighian tubule morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_kidney_jan10") "The movement of an epithelial cell with respect to other epithelial cells that contributes to the shaping of the Malpighian tubule.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-09-28T02:04:05Z") +AnnotationAssertion( "cell migration involved in Malpighian tubule morphogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061334") +AnnotationAssertion(rdfs:label "cell rearrangement involved in Malpighian tubule morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (cell growth involved in Malpighian tubule morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_kidney_jan10") Annotation( "PMID:19783135") "The growth of an epithelial cell dependent on cycles of endoreplication, where growth contributes to the shaping of the Malpighian tubule.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-09-28T02:08:25Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061335") +AnnotationAssertion(rdfs:label "cell growth involved in Malpighian tubule morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (cell morphogenesis involved in Malpighian tubule morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_kidney_jan10") Annotation( "PMID:19783135") "The shape change of an epithelial cell from a columnar to squamous cell morphology that contributes to the shaping of the Malpighian tubule.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-09-28T02:11:47Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061336") +AnnotationAssertion(rdfs:label "cell morphogenesis involved in Malpighian tubule morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (cardiac conduction) + +AnnotationAssertion(Annotation( "GOC:dph") "Transfer of an organized electrical impulse across the heart to coordinate the contraction of cardiac muscles. The process begins with generation of an action potential (in the sinoatrial node (SA) in humans) and ends with a change in the rate, frequency, or extent of the contraction of the heart muscles.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-09-29T08:46:05Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061337") +AnnotationAssertion(rdfs:label "cardiac conduction") +SubClassOf( ) + +# Class: (cell adhesion involved in heart morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_heart") Annotation( "PMID:16860783") "The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules that contributes to the shaping of the heart.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-09-29T11:34:06Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061343") +AnnotationAssertion(rdfs:label "cell adhesion involved in heart morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of cell adhesion involved in heart morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_heart") Annotation( "PMID:16860783") "Any process that modulates the extent of cell adhesion contributing to the shaping of the heart.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-09-29T11:35:27Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061344") +AnnotationAssertion(rdfs:label "regulation of cell adhesion involved in heart morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (neural precursor cell proliferation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:yaf") "The multiplication or reproduction of neural precursor cells, resulting in the expansion of a cell population. A neural precursor cell is either a nervous system stem cell or a nervous system progenitor cell.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-10-01T11:06:04Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061351") +AnnotationAssertion(rdfs:label "neural precursor cell proliferation") +SubClassOf( ) + +# Class: (cell chemotaxis involved in Malpighian tubule morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_kidney_jan10") "The directed movement of the outgrowing Malpighian tubule guided by specific chemical cues/signals. Movement may be towards a guidance cue (positive chemotaxis) or away from it (negative chemotaxis). Guidance contributes to the final positioning of the tubule.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-10-01T11:57:28Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061352") +AnnotationAssertion(rdfs:label "cell chemotaxis involved in Malpighian tubule morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (optic chiasma development) + +AnnotationAssertion(Annotation( "GOC:dph") "The developmental process pertaining to the progression of the optic chiasm from its initial formation to the mature structure. The process begins when the pathfinding of the axons of the developing optic nerve cause some axons to cross at the midline of the brain and ends when the axons are mature.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-10-13T08:00:29Z") +AnnotationAssertion(Annotation( "GOC:dph") "optic chiasm development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061360") +AnnotationAssertion(rdfs:label "optic chiasma development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (testosterone biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:yaf") "The chemical reactions and pathways resulting in the formation of testosterone, an androgen having 17beta-hydroxy and 3-oxo groups, together with unsaturation at C-4 C-5.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-10-27T02:50:48Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061370") +AnnotationAssertion(rdfs:label "testosterone biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (mammillary axonal complex development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:yaf") Annotation( "PMID:10662642") "The progression of the mammillary axonal complex over time, from its formation to the mature structure. The mammillary axonal complex is formed by the axons from the lateral, medial mammillary and the dorsal premammillary nuclei which share a branching pattern. Every neuron gives off one axonal stem that bifurcates into 2 branches. One of the branches is directed dorsally to the thalamus and another caudally to the midbrain.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-11-09T08:49:59Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061373") +AnnotationAssertion(rdfs:label "mammillary axonal complex development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (mammillothalamic axonal tract development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:yaf") Annotation( "PMID:10662642") "The progression of the mammillothalamic axonal tract, from its formation to the mature structure. The mammillothalamic tract is the collection of axons that connects the two major subdivisions of the diencephalon (hypothalamus and thalamus) and closes the diencephalic circuit.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-11-09T08:54:43Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061374") +AnnotationAssertion(rdfs:label "mammillothalamic axonal tract development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (mammillotectal axonal tract development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:yaf") Annotation( "PMID:10662642") "The progression of the mammillotectal tract over time, from its formation to the mature structure. The mammillotectal tract is the collection of axons that connects the ventral diencephalon to the superior colliculus.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-11-09T09:01:14Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061375") +AnnotationAssertion(rdfs:label "mammillotectal axonal tract development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (mammillotegmental axonal tract development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:yaf") Annotation( "PMID:10662642") "The process in which the mammillotegmental tract progresses over time, from its formation to the mature structure. The mammillotegmental tract is the collection of axons that connects the ventral diencephalon to the tegmentum and pons.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-11-09T09:09:29Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061376") +AnnotationAssertion(rdfs:label "mammillotegmental axonal tract development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (mammary gland lobule development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:yaf") "The progression of the mammary gland lobule over time, from its formation to the mature structure. A mammary gland lobule is a small rounded projection of the mammary gland.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-11-09T09:36:29Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061377") +AnnotationAssertion(rdfs:label "mammary gland lobule development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (corpora quadrigemina development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:yaf") "The progression of the corpora quadrigemina over time, from its formation to the mature structure. The corpora quadrigemina is a part of the midbrain that is made up of the superior and inferior colliculi.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-11-09T09:45:36Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061378") +AnnotationAssertion(rdfs:label "corpora quadrigemina development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (inferior colliculus development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:yaf") "The process whose specific outcome is the progression of the inferior colliculus over time, from its formation to the mature structure. The inferior colliculus (IC) (Latin, lower hill) is the principal midbrain nucleus of the auditory pathway and receives input from several more peripheral brainstem nuclei in the auditory pathway, as well as inputs from the auditory cortex. The inferior colliculus has three subdivisions: the central nucleus (CIC), a dorsal cortex (DCIC) by which it is surrounded, and an external cortex (ICX) which is located laterally.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-11-09T09:49:24Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061379") +AnnotationAssertion(rdfs:label "inferior colliculus development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (superior colliculus development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:yaf") "The process whose specific outcome is the progression of the superior colliculus over time, from its formation to the mature structure. The superior colliculus is also known as the optic tectum or simply tectum and is a paired structure that forms a major component of the vertebrate midbrain.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-11-09T09:51:00Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061380") +AnnotationAssertion(rdfs:label "superior colliculus development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (trabecula morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") "The process of shaping a trabecula in an organ. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-12-02T08:51:45Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061383") +AnnotationAssertion(rdfs:label "trabecula morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (heart trabecula morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") "The process of shaping a trabecula in the heart. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-12-02T08:54:20Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061384") +AnnotationAssertion(rdfs:label "heart trabecula morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (fibroblast proliferation involved in heart morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") "The multiplication or reproduction of fibroblasts, resulting in the expansion of a fibroblast population that contributes to the shaping of the heart.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2011-02-10T01:41:59Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061385") +AnnotationAssertion(rdfs:label "fibroblast proliferation involved in heart morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (bone trabecula morphogenesis) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:vk") "The process of shaping a trabecula in bone. A trabecula is a tissue element in the form of a small beam, strut or rod.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2012-02-07T10:15:36Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061430") +AnnotationAssertion(rdfs:label "bone trabecula morphogenesis") +SubClassOf( ) + +# Class: (renal system vasculature development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_kidney_jan10") Annotation( "PMID:11891195") "The process whose specific outcome is the progression of vasculature of the renal system over time, from its formation to the mature structure.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2012-03-08T12:16:24Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061437") +AnnotationAssertion(rdfs:label "renal system vasculature development") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (renal system vasculature morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_kidney_jan10") Annotation( "PMID:11891195") "The process in which the renal system vasculature is generated and organized. Morphogenesis pertains to the creation of form.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2012-03-08T12:21:56Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061438") +AnnotationAssertion(rdfs:label "renal system vasculature morphogenesis") +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (kidney vasculature morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_kidney_jan10") "The process in which the kidney vasculature is generated and organized. Morphogenesis pertains to the creation of form.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2012-03-08T12:30:11Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061439") +AnnotationAssertion(rdfs:label "kidney vasculature morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (kidney vasculature development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mtg_kidney_jan10") Annotation( "PMID:11891195") "The process whose specific outcome is the progression of the vasculature of the kidney over time, from its formation to the mature structure.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2012-03-08T12:39:09Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061440") +AnnotationAssertion(rdfs:label "kidney vasculature development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (renal artery morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") Annotation( "PMID:11891195") "The process in which the anatomical structure of a renal artery is generated and organized. Renal arteries supply the kidneys with blood.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2012-03-08T12:42:09Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061441") +AnnotationAssertion(rdfs:label "renal artery morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (connective tissue development) AnnotationAssertion(Annotation( "GOC:BHF") "The progression of a connective tissue over time, from its formation to the mature structure.") @@ -40049,8 +102686,80 @@ AnnotationAssertion( AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0061448") AnnotationAssertion(rdfs:label "connective tissue development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (olfactory bulb tufted cell development) + +AnnotationAssertion(Annotation( "GOC:dph") "The process whose specific outcome is the progression of an olfactory bulb tufted cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2012-05-15T12:30:21Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061449") +AnnotationAssertion(rdfs:label "olfactory bulb tufted cell development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (trophoblast cell migration) + +AnnotationAssertion(Annotation( "GOC:dph") "Trophoblast cell migration that is accomplished by extension and retraction of a pseudopodium. Trophoblast cells line the outside of the blastocyst.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2012-07-10T08:38:37Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061450") +AnnotationAssertion(rdfs:label "trophoblast cell migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (retrotrapezoid nucleus development) + +AnnotationAssertion(Annotation( "GOC:dph") "The progression of the retrotrapezoid nucleus (RTN) over time from it's initial formation to its mature state. The retrotrapezoid nucleus is a group of neurons in the rostral medulla, which are responsible regulating respiration.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2012-07-19T12:38:30Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061451") +AnnotationAssertion(rdfs:label "retrotrapezoid nucleus development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (retrotrapezoid nucleus neuron differentiation) + +AnnotationAssertion(Annotation( "GOC:dph") "The process in which a relatively unspecialized cell acquires specialized features of a neuron whose cell body resides in the retrotrapezoid nucleus.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2012-07-19T12:43:18Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061452") +AnnotationAssertion(rdfs:label "retrotrapezoid nucleus neuron differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (interstitial cell of Cajal differentiation) + +AnnotationAssertion(Annotation( "GOC:dph") "The process in which a relatively unspecialized cell acquires specialized features of an interstitial cell of Cajal. An interstitial cell of Cajal is an intestinal neuroepithelial cell that serves as a pacemaker to trigger gut contraction.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2012-07-20T08:20:50Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") "ICC differentiation") +AnnotationAssertion( "GO:0061453") +AnnotationAssertion(rdfs:label "interstitial cell of Cajal differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (release of sequestered calcium ion into cytosol by Golgi) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "The directed movement of calcium ions (Ca2+) out of the Golgi apparatus into the cytosol.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2012-07-27T02:29:43Z") +AnnotationAssertion( "Golgi calcium ion export") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061454") +AnnotationAssertion(rdfs:label "release of sequestered calcium ion into cytosol by Golgi") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + # Class: (reproductive system development) AnnotationAssertion(Annotation( "GOC:dph") "The progression of the reproductive system over time from its formation to the mature structure. The reproductive system consists of the organs that function in reproduction.") @@ -40059,8 +102768,221 @@ AnnotationAssertion( AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0061458") AnnotationAssertion(rdfs:label "reproductive system development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (protein localization to lysosome) + +AnnotationAssertion(Annotation( "GOC:dph") "A process in which a protein is transported to, or maintained in, a location within a lysosome.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2012-10-05T10:50:51Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061462") +AnnotationAssertion(rdfs:label "protein localization to lysosome") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of type B pancreatic cell proliferation) + +AnnotationAssertion(Annotation( "GOC:dph") "Any process that modulates the frequency, rate or extent of type B pancreatic cell proliferation.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2012-11-01T13:16:23Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061469") +AnnotationAssertion(rdfs:label "regulation of type B pancreatic cell proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (hematopoietic stem cell homeostasis) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:21508411") "Any biological process involved in the maintenance of the steady-state number of hematopoietic stem cells within a population of cells.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2012-12-04T09:41:02Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061484") +AnnotationAssertion(rdfs:label "hematopoietic stem cell homeostasis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (protein localization to cilium) + +AnnotationAssertion(Annotation( "GOC:dph") "A process in which a protein is transported to, or maintained in, a location within a cilium.") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( "dph") +AnnotationAssertion( "2013-03-22T15:41:44Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061512") +AnnotationAssertion(rdfs:label "protein localization to cilium") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) +SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) +SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) +SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) +SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) +SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) +SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) +SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) +SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) +SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) +SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) +SubClassOf( ObjectAllValuesFrom( )) +DisjointClasses( ObjectSomeValuesFrom( )) +DisjointClasses( ObjectSomeValuesFrom( )) +DisjointClasses( ObjectSomeValuesFrom( )) +DisjointClasses( ObjectSomeValuesFrom( )) +DisjointClasses( ObjectSomeValuesFrom( )) +DisjointClasses( ObjectSomeValuesFrom( )) + +# Class: (myeloid cell development) + +AnnotationAssertion(Annotation( "GOC:dph") "The process whose specific outcome is the progression of a myeloid cell over time, from its formation to the mature structure.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2013-04-18T13:03:16Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061515") +AnnotationAssertion(rdfs:label "myeloid cell development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (macrophage homeostasis) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:21727904") "The process of regulating the proliferation and elimination of macrophage cells such that the total number of myeloid cells within a whole or part of an organism is stable over time in the absence of an outside stimulus.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2013-04-18T13:25:33Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061519") +AnnotationAssertion(rdfs:label "macrophage homeostasis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (Langerhans cell differentiation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:22729249") "The process in which a precursor cell type acquires the specialized features of a Langerhans cell.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2013-04-18T13:29:07Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061520") +AnnotationAssertion(rdfs:label "Langerhans cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (hepatic stellate cell differentiation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:9407545") "The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a hepatic stellate cell.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2013-04-18T13:36:08Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061521") +AnnotationAssertion(rdfs:label "hepatic stellate cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (cilium disassembly) + +AnnotationAssertion(Annotation( "GOC:cilia") Annotation( "GOC:dph") Annotation( "PMID:17604723") Annotation( "PMID:27350441") "A cellular process that results in the breakdown of a cilium.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2013-04-18T14:59:59Z") +AnnotationAssertion(Annotation( "GOC:dph") "cilium resorption") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061523") +AnnotationAssertion(rdfs:comment "Note that we deem cilium and microtubule-based flagellum to be equivalent.") +AnnotationAssertion(rdfs:label "cilium disassembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (central canal development) + +AnnotationAssertion(Annotation( "GOC:cvs") Annotation( "GOC:dph") Annotation( "PMID:23409159") "The process whose specific outcome is the formation of the central canal of the spinal cord from its formation to the mature structure. The central canal is a spinal cord structure that is part of the ventricular system and is filled with cerebral-spinal fluid and runs the length of the spinal cord.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2013-04-20T08:18:31Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061524") +AnnotationAssertion(rdfs:label "central canal development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (hindgut development) + +AnnotationAssertion(Annotation( "GOC:dph") "The process whose specific outcome is the progression of the hindgut over time, from its formation to the mature structure. The hindgut is part of the alimentary canal that lies posterior to the midgut.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2013-06-14T11:22:21Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061525") +AnnotationAssertion(rdfs:label "hindgut development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (acetylcholine secretion) + +AnnotationAssertion(Annotation( "GOC:dph") "The regulated release of acetylcholine by a cell.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2013-06-21T15:40:39Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061526") +AnnotationAssertion(rdfs:label "acetylcholine secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (dopamine secretion, neurotransmission) + +AnnotationAssertion(Annotation( "GOC:dph") "The regulated release of dopamine by a cell in which the dopamine acts as a neurotransmitter.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2013-06-21T15:43:15Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061527") +AnnotationAssertion(rdfs:label "dopamine secretion, neurotransmission") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (epinephrine secretion, neurotransmission) + +AnnotationAssertion(Annotation( "GOC:dph") "The regulated release of epinephrine by a cell in which the epinephrine acts as a neurotransmitter.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2013-06-21T15:47:22Z") +AnnotationAssertion(Annotation( "GOC:dph") "adrenaline secretion, neurotransmission") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061529") +AnnotationAssertion(rdfs:label "epinephrine secretion, neurotransmission") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (norepinephrine secretion, neurotransmission) + +AnnotationAssertion(Annotation( "GOC:dph") "The regulated release of norepinephrine by a cell, in which the norepinephrine acts as a neurotransmitter.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2013-06-21T16:05:08Z") +AnnotationAssertion(Annotation( "GOC:dph") "noradrenaline secretion, neurotransmission") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061533") +AnnotationAssertion(rdfs:label "norepinephrine secretion, neurotransmission") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (gamma-aminobutyric acid secretion, neurotransmission) + +AnnotationAssertion(Annotation( "GOC:dph") "The regulated release of gamma-aminobutyric acid by a cell, in which the gamma-aminobutyric acid acts as a neurotransmitter.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2013-06-21T16:10:50Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061534") +AnnotationAssertion(rdfs:label "gamma-aminobutyric acid secretion, neurotransmission") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (glutamate secretion, neurotransmission) AnnotationAssertion(Annotation( "GOC:dph") "The controlled release of glutamate by a cell, in which the glutamate acts as a neurotransmitter.") @@ -40069,10 +102991,356 @@ AnnotationAssertion( AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0061535") AnnotationAssertion(rdfs:label "glutamate secretion, neurotransmission") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (ganglion development) + +AnnotationAssertion(Annotation( "GOC:dph") "The process whose specific outcome is the progression of a ganglion over time, from its formation to the mature structure.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2013-07-10T08:36:12Z") +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:rl") "gangliogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") "ganglia development") +AnnotationAssertion( "GO:0061548") +AnnotationAssertion(rdfs:label "ganglion development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (sympathetic ganglion development) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:rl") "The process whose specific outcome is the progression of a sympathetic ganglion over time, from its formation to the mature structure.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2013-07-10T08:38:01Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") "sympathetic ganglia development") +AnnotationAssertion( "GO:0061549") +AnnotationAssertion(rdfs:label "sympathetic ganglion development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cranial ganglion development) + +AnnotationAssertion(Annotation( "GOC:dph") "The process whose specific outcome is the progression of a cranial ganglion over time, from its formation to the mature structure.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2013-07-10T08:40:14Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") "cranial ganglia development") +AnnotationAssertion( "GO:0061550") +AnnotationAssertion(rdfs:label "cranial ganglion development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (trigeminal ganglion development) + +AnnotationAssertion(Annotation( "GOC:dph") "The process whose specific outcome is the progression of a trigeminal ganglion over time, from its formation to the mature structure.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2013-07-10T08:42:19Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") "trigeminal ganglia development") +AnnotationAssertion( "GO:0061551") +AnnotationAssertion(rdfs:label "trigeminal ganglion development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (ganglion morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") "The process in which the anatomical structures of ganglion are generated and organized.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2013-07-10T08:44:57Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") "ganglia morphogenesis") +AnnotationAssertion( "GO:0061552") +AnnotationAssertion(rdfs:label "ganglion morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (ganglion maturation) + +AnnotationAssertion(Annotation( "GOC:dph") "A developmental process, independent of morphogenetic (shape) change, that is required for ganglion to attain its fully functional state.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2013-07-10T08:45:59Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") "ganglia maturation") +AnnotationAssertion( "GO:0061553") +AnnotationAssertion(rdfs:label "ganglion maturation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (ganglion formation) + +AnnotationAssertion(Annotation( "GOC:dph") "The process that gives rise to ganglion. This process pertains to the initial formation of a structure from unspecified parts.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2013-07-10T08:51:50Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") "ganglia formation") +AnnotationAssertion( "GO:0061554") +AnnotationAssertion(rdfs:label "ganglion formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (trigeminal ganglion morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") "The process in which the anatomical structure of a trigeminal ganglion is generated and organized.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2013-07-10T08:57:12Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") "trigeminal ganglia morphogenesis") +AnnotationAssertion( "GO:0061556") +AnnotationAssertion(rdfs:label "trigeminal ganglion morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (trigeminal ganglion maturation) + +AnnotationAssertion(Annotation( "GOC:dph") "A developmental process, independent of morphogenetic (shape) change, that is required for a trigeminal ganglion to attain its fully functional state.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2013-07-10T08:58:24Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") "trigeminal ganglia maturation") +AnnotationAssertion( "GO:0061557") +AnnotationAssertion(rdfs:label "trigeminal ganglion maturation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cranial ganglion maturation) + +AnnotationAssertion(Annotation( "GOC:dph") "A developmental process, independent of morphogenetic (shape) change, that is required for a cranial ganglion to attain its fully functional state.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2013-07-10T08:59:52Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") "cranial ganglia maturation") +AnnotationAssertion( "GO:0061558") +AnnotationAssertion(rdfs:label "cranial ganglion maturation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cranial ganglion morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") "The process in which the anatomical structure of a cranial ganglion is generated and organized.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2013-07-10T09:02:15Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") "cranial ganglia morphogenesis") +AnnotationAssertion( "GO:0061559") +AnnotationAssertion(rdfs:label "cranial ganglion morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cranial ganglion formation) + +AnnotationAssertion(Annotation( "GOC:dph") "The process that gives rise to a cranial ganglion. This process pertains to the initial formation of a structure from unspecified parts.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2013-07-10T09:07:27Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") "cranial ganglia formation") +AnnotationAssertion( "GO:0061560") +AnnotationAssertion(rdfs:label "cranial ganglion formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (trigeminal ganglion formation) + +AnnotationAssertion(Annotation( "GOC:dph") "The process that gives rise to the trigeminal ganglion. This process pertains to the initial formation of a structure from unspecified parts.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2013-07-10T09:08:13Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") "trigeminal ganglia formation") +AnnotationAssertion( "GO:0061561") +AnnotationAssertion(rdfs:label "trigeminal ganglion formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (axon development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:pg") Annotation( "GOC:pr") "The progression of an axon over time. Covers axonogenesis (de novo generation of an axon) and axon regeneration (regrowth), as well as processes pertaining to the progression of the axon over time (fasciculation and defasciculation).") +AnnotationAssertion( "dph") +AnnotationAssertion( "2013-07-18T14:43:01Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061564") +AnnotationAssertion(rdfs:label "axon development") +SubClassOf( ) + +# Class: (actin filament bundle organization) + +AnnotationAssertion(Annotation( "GOC:dph") "A process that results in the assembly, arrangement of constituent parts, or disassembly of an actin filament bundle.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2013-08-02T11:24:11Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") "actin filament cable organization") +AnnotationAssertion( "GO:0061572") +AnnotationAssertion(rdfs:label "actin filament bundle organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (colon epithelial cell migration) + +AnnotationAssertion(Annotation( "GOC:dph") "The orderly movement of a colonic epithelial cell from one site to another, often during the development of a multicellular organism.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2013-12-23T07:26:54Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061580") +AnnotationAssertion(rdfs:label "colon epithelial cell migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (corneal epithelial cell migration) + +AnnotationAssertion(Annotation( "GOC:dph") "The orderly movement of a corneal epithelial cell from one site to another, often during the development of a multicellular organism.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2013-12-23T07:28:29Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061581") +AnnotationAssertion(rdfs:label "corneal epithelial cell migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (intestinal epithelial cell migration) + +AnnotationAssertion(Annotation( "GOC:dph") "The orderly movement of an intestinal epithelial cell from one site to another, often during the development of a multicellular organism.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2013-12-23T07:30:55Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061582") +AnnotationAssertion(rdfs:label "intestinal epithelial cell migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (pharyngeal arch artery morphogenesis) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "PMID:20122914") "The process in which the anatomical structures of a pharyngeal arch artery is generated and organized. The pharyngeal arch arteries are a series of six paired embryological vascular structures, the development of which give rise to several major arteries, such as the stapedial artery, the middle meningeal artery, the internal carotid artery and the pulmonary artery.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2014-05-09T15:34:06Z") +AnnotationAssertion(Annotation( "GOC:dph") "aortic arch artery morphogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061626") +AnnotationAssertion(rdfs:label "pharyngeal arch artery morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (RNA polymerase II-specific DNA-binding transcription factor binding) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:vw") "Binding to a sequence-specific DNA binding RNA polymerase II transcription factor, any of the factors that interact selectively and non-covalently with a specific DNA sequence in order to modulate transcription.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/19354"^^xsd:anyURI) +AnnotationAssertion( "dph") +AnnotationAssertion( "2014-05-15T09:12:24Z") +AnnotationAssertion( "GO:0001085") +AnnotationAssertion( "GO:0001102") +AnnotationAssertion( "GO:0001103") +AnnotationAssertion( "RNA polymerase II sequence-specific DNA binding transcription factor binding") +AnnotationAssertion( "RNA polymerase II sequence-specific DNA-binding transcription factor binding") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "RNA polymerase II activating transcription factor binding") +AnnotationAssertion( "RNA polymerase II repressing transcription factor binding") +AnnotationAssertion( "RNA polymerase II transcription factor binding") +AnnotationAssertion( "GO:0061629") +AnnotationAssertion(rdfs:label "RNA polymerase II-specific DNA-binding transcription factor binding") +SubClassOf( ) + +# Class: (seminal vesicle morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") "The process in which the anatomical structures of a seminal vesicle are generated and organized.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2015-03-04T13:33:49Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061682") +AnnotationAssertion(rdfs:label "seminal vesicle morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (branching involved in seminal vesicle morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "PMID:16916376") "The process in which the branching structure of the seminal vesicle is generated and organized. A branch is a division or offshoot from a main stem.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2015-03-04T13:39:47Z") +AnnotationAssertion(Annotation( "GOC:dph") "gonecyst branching morphogenesis") +AnnotationAssertion(Annotation( "GOC:dph") "seminal gland branching morphogenesis") +AnnotationAssertion(Annotation( "GOC:dph") "seminal vesicle branching") +AnnotationAssertion(Annotation( "GOC:dph") "seminal vesicle branching morphogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061683") +AnnotationAssertion(rdfs:label "branching involved in seminal vesicle morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (detoxification of inorganic compound) + +AnnotationAssertion(Annotation( "GOC:vw") "Any process that reduces or removes the toxicity of inorganic compounds. These include transport of such compounds away from sensitive areas and to compartments or complexes whose purpose is sequestration of inorganic compounds.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2015-03-09T09:16:23Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061687") +AnnotationAssertion(rdfs:label "detoxification of inorganic compound") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (transferase complex, transferring phosphorus-containing groups) + +AnnotationAssertion(Annotation( "GOC:bhm") Annotation( "GOC:dph") "A transferase complex capable of catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor).") +AnnotationAssertion( "dph") +AnnotationAssertion( "2015-05-06T11:22:38Z") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0061695") +AnnotationAssertion(rdfs:label "transferase complex, transferring phosphorus-containing groups") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (anterior neural tube closure) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dph") Annotation( "GOC:hal") Annotation( "PMID:17286298") "The step in the formation of the neural tube, where the paired anterior neural folds are brought together and fuse at the dorsal midline.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2015-06-23T10:13:41Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061713") +AnnotationAssertion(rdfs:label "anterior neural tube closure") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cytosolic lipolysis) + +AnnotationAssertion(Annotation( "GOC:autophagy") "The chemical reactions and pathways resulting in the breakdown of lipid droplets and hydrolysis of stored triglycerides occurring through the orchestrated activation of cytosolic lipases.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2015-07-08T13:42:15Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061725") +AnnotationAssertion(rdfs:label "cytosolic lipolysis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (secretory granule maturation) + +AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:bf") Annotation( "GOC:dph") Annotation( "PMID:16618809") "Steps required to transform an immature secretory vesicle into a mature secretory vesicle. Typically proceeds through homotypic membrane fusion and membrane remodeling.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2016-09-09T13:24:34Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061792") +AnnotationAssertion(rdfs:label "secretory granule maturation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + # Class: (antimicrobial humoral immune response mediated by antimicrobial peptide) AnnotationAssertion(Annotation( "PMID:15761415") Annotation( "PMID:24287494") "An immune response against microbes mediated by anti-microbial peptides in body fluid.") @@ -40083,6 +103351,268 @@ AnnotationAssertion( "antimicrobial humoral immune response mediated by antimicrobial peptide") SubClassOf( ) +# Class: (regulation of neuroblast migration) + +AnnotationAssertion(Annotation( "PMID:23149556") "Any process that modulates the frequency, rate or extent of neuroblast migration.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2017-03-08T18:17:07Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061853") +AnnotationAssertion(rdfs:label "regulation of neuroblast migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of neuroblast migration) + +AnnotationAssertion(Annotation( "PMID:23149556") "Any process that activates or increases the frequency, rate or extent of neuroblast migration.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2017-03-08T18:22:30Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061854") +AnnotationAssertion(rdfs:label "positive regulation of neuroblast migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of neuroblast migration) + +AnnotationAssertion(Annotation( "PMID:23149556") "Any process that stops, prevents, or reduces the frequency, rate or extent of neuroblast migration.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2017-03-08T18:26:21Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061855") +AnnotationAssertion(rdfs:label "negative regulation of neuroblast migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (Golgi calcium ion transmembrane transport) + +AnnotationAssertion(Annotation( "PMID:21811607") "A process in which a calcium ion is transported from one side of a Golgi membrane to the other by means of some agent such as a transporter or pore.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2017-03-14T16:08:23Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061856") +AnnotationAssertion(rdfs:label "Golgi calcium ion transmembrane transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (hepatic stellate cell migration) + +AnnotationAssertion(Annotation( "PMID:24204762") "The orderly movement of a hepatic stellate cell from one site to another.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2017-05-01T13:01:40Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061868") +AnnotationAssertion(rdfs:label "hepatic stellate cell migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of hepatic stellate cell migration) + +AnnotationAssertion(Annotation( "PMID:24204762") "Any process that modulates the frequency, rate or extent of hepatic stellate cell migration.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2017-05-01T13:04:20Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061869") +AnnotationAssertion(rdfs:label "regulation of hepatic stellate cell migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of hepatic stellate cell migration) + +AnnotationAssertion(Annotation( "PMID:24204762") "Any process that increases the frequency, rate or extent of hepatic stellate cell migration.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2017-05-01T13:17:23Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061870") +AnnotationAssertion(rdfs:label "positive regulation of hepatic stellate cell migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of hepatic stellate cell migration) + +AnnotationAssertion(Annotation( "PMID:24204762") "Any process that stops, prevents or reduces the frequency, rate or extent of hepatic stellate cell migration.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2017-05-01T13:20:51Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061871") +AnnotationAssertion(rdfs:label "negative regulation of hepatic stellate cell migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of astrocyte activation) + +AnnotationAssertion(Annotation( "GOC:aruk") Annotation( "GOC:bc") Annotation( "PMID:20005821") "Any process that modulates the frequency, rate or extent of astrocyte activation.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2017-06-01T22:26:29Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061888") +AnnotationAssertion(rdfs:label "regulation of astrocyte activation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (negative regulation of astrocyte activation) + +AnnotationAssertion(Annotation( "GOC:aruk") Annotation( "GOC:bc") Annotation( "PMID:20005821") "Any process that decreases the frequency, rate or extent of astrocyte activation.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2017-06-01T22:29:43Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061889") +AnnotationAssertion(rdfs:label "negative regulation of astrocyte activation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (positive regulation of astrocyte activation) + +AnnotationAssertion(Annotation( "GOC:aruk") Annotation( "GOC:bc") Annotation( "PMID:20005821") "Any process that increases the frequency, rate or extent of astrocyte activation.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2017-06-01T22:31:50Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061890") +AnnotationAssertion(rdfs:label "positive regulation of astrocyte activation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (glial cell activation) + +AnnotationAssertion(Annotation( "GOC:aruk") Annotation( "GOC:bc") Annotation( "PMID:18723082") "A change in morphology and behavior of a glial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2017-06-13T13:06:23Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061900") +AnnotationAssertion(rdfs:label "glial cell activation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (regulation of adenine biosynthetic process) + +AnnotationAssertion(Annotation( "PMID:19933844") "Any process that modulates the frequency, rate or extent of an adenine biosynthetic process.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2017-09-05T14:58:46Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061934") +AnnotationAssertion(rdfs:label "regulation of adenine biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (protein localization to somatodendritic compartment) + +AnnotationAssertion(Annotation( "PMID:18341993") "A process in which a protein is transported to or maintained in a location within the somatodendritic compartment.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2017-09-08T13:22:26Z") +AnnotationAssertion( "somatodendritic protein localization") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061938") +AnnotationAssertion(rdfs:label "protein localization to somatodendritic compartment") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (establishment of protein localization to plasma membrane) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:vw") "The directed movement of a protein to a specific location in a plasma membrane.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2017-10-26T12:55:15Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061951") +AnnotationAssertion(rdfs:label "establishment of protein localization to plasma membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (replacement bone morphogenesis) + +AnnotationAssertion(Annotation( "PMID:29852585") "The process in which bones are generated and organized as a result of the conversion of another structural tissue into bone.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2018-02-12T18:10:59Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061971") +AnnotationAssertion(rdfs:label "replacement bone morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (dermal bone morphogenesis) + +AnnotationAssertion(Annotation( "PMID:12588850") Annotation( "PMID:15003632") "The process in which bone which forms superficially in the organism are generated and organized.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2018-02-12T18:16:21Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061972") +AnnotationAssertion(rdfs:label "dermal bone morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (membrane bone morphogenesis) + +AnnotationAssertion(Annotation( "PMID:14579374") "The process in which bone which forms deep in the organism are generated and organized.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2018-02-12T18:21:09Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061973") +AnnotationAssertion(rdfs:label "membrane bone morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (perichondral bone morphogenesis) + +AnnotationAssertion(Annotation( "PMID:21901110") "The process in which bones are generated and organized as a result of the conversion of initial connective tissue surrounding cartilage into bone.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2018-02-12T18:26:10Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061974") +AnnotationAssertion(rdfs:label "perichondral bone morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (meiosis II cell cycle process) + +AnnotationAssertion(Annotation( "PMID:29385397") "A process that coontributes to the second meiotic division. The second meiotic division separates chromatids resulting in a haploid number of chromosomes.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2018-02-14T22:37:44Z") +AnnotationAssertion(Annotation( "PMID:29385397") "second meiotic division") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0061983") +AnnotationAssertion(rdfs:label "meiosis II cell cycle process") +SubClassOf( ) + +# Class: (secondary palate development) + +AnnotationAssertion(Annotation( "PMID:28784960") "The biological process whose specific outcome is the progression of the secondary palate from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The secondary palate is the part of the palate formed from the fusion of the two palatine shelves, extensions of the maxillary prominences.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2018-02-26T22:55:20Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0062009") +AnnotationAssertion(rdfs:label "secondary palate development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (primitive palate development) + +AnnotationAssertion(Annotation( "GOC:dph") "The biological process whose specific outcome is the progression of the primitive palate from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2018-02-26T23:00:48Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0062010") +AnnotationAssertion(rdfs:label "primitive palate development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of small molecule metabolic process) + +AnnotationAssertion(Annotation( "GOC:vw") "Any process that modulates the rate, frequency or extent of a small molecule metabolic process.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2018-03-19T14:11:54Z") +AnnotationAssertion( "regulation of small molecule metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0062012") +AnnotationAssertion(rdfs:label "regulation of small molecule metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of small molecule metabolic process) + +AnnotationAssertion(Annotation( "GOC:vw") "Any process that activates or increases the frequency, rate or extent of a small molecule metabolic process.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2018-03-19T14:25:10Z") +AnnotationAssertion( "positive regulation of small molecule metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0062013") +AnnotationAssertion(rdfs:label "positive regulation of small molecule metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of small molecule metabolic process) + +AnnotationAssertion(Annotation( "GOC:vw") "Any process that stops, prevents or reduces the frequency, rate or extent of a small molecule metabolic process.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2018-03-19T14:27:23Z") +AnnotationAssertion( "negative regulation of small molecule metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0062014") +AnnotationAssertion(rdfs:label "negative regulation of small molecule metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (collagen-containing extracellular matrix) AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:rph") Annotation( "PMID:21123617") "An extracellular matrix consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that provides not only essential physical scaffolding for the cellular constituents but can also initiate crucial biochemical and biomechanical cues required for tissue morphogenesis, differentiation and homeostasis. The components are secreted by cells in the vicinity and form a sheet underlying or overlying cells such as endothelial and epithelial cells.") @@ -40095,6 +103625,136 @@ SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectAllValuesFrom( )) +# Class: (positive regulation of mitotic sister chromatid segregation) + +AnnotationAssertion(Annotation( "PMID:12773390") "Any process that starts or increases the frequency, rate or extent of sister chromatid segregation during mitosis.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2018-04-23T14:32:23Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0062033") +AnnotationAssertion(rdfs:label "positive regulation of mitotic sister chromatid segregation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (stomach development) + +AnnotationAssertion(Annotation( "PMID:11967278") "The process whose specific outcome is the progression of the stomach over time, from its formation to the mature structure. The stomach is an expanded region of the vertebrate alimentary tract that serves as a food storage compartment and digestive organ.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2018-11-20T18:15:45Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0062094") +AnnotationAssertion(rdfs:label "stomach development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (detection of stimulus involved in sensory perception of pain) + +AnnotationAssertion(Annotation( "PMID:19837031") "The series of events involved in the perception of pain in which a stimulus is received and converted into a molecular signal.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2019-09-13T13:48:47Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0062149") +AnnotationAssertion(rdfs:label "detection of stimulus involved in sensory perception of pain") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (lutein metabolic process) + +AnnotationAssertion(Annotation( "PMID:24397433") "The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform lutein.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2019-11-18T15:56:36Z") +AnnotationAssertion( "lutein metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0062170") +AnnotationAssertion(rdfs:label "lutein metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (lutein biosynthetic process) + +AnnotationAssertion(Annotation( "PMID:24397433") "The chemical reactions and pathways resulting in the formation of lutein.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2019-11-18T16:01:00Z") +AnnotationAssertion( "lutein anabolism") +AnnotationAssertion( "lutein biosynthesis") +AnnotationAssertion( "lutein formation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0062171") +AnnotationAssertion(rdfs:label "lutein biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (lutein catabolic process) + +AnnotationAssertion(Annotation( "PMID:24397433") "The chemical reactions and pathways resulting in the breakdown of lutein.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2019-11-18T16:06:07Z") +AnnotationAssertion( "lutein breakdown") +AnnotationAssertion( "lutein catabolism") +AnnotationAssertion( "lutein degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0062172") +AnnotationAssertion(rdfs:label "lutein catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of somatic muscle development) + +AnnotationAssertion(Annotation( "PMID:16643882") Annotation( "PMID:25758712") "Any process that regulates the rate, frequency or extent of somatic muscle development.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2020-03-13T18:58:37Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0062223") +AnnotationAssertion(rdfs:label "regulation of somatic muscle development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of somatic muscle development) + +AnnotationAssertion(Annotation( "PMID:16643882") Annotation( "PMID:25758712") "Any process that increases the rate, frequency or extent of somatic muscle development.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2020-03-13T19:03:38Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0062224") +AnnotationAssertion(rdfs:label "positive regulation of somatic muscle development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of somatic muscle development) + +AnnotationAssertion(Annotation( "PMID:16643882") Annotation( "PMID:25758712") "Any process that decreases the rate, frequency or extent of somatic muscle development.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2020-03-13T19:06:27Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0062225") +AnnotationAssertion(rdfs:label "negative regulation of somatic muscle development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (ionocyte differentiation) + +AnnotationAssertion(Annotation( "PMID:17555741") "The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of an ionocyte. Ionocytes are specialized epithelial cells that contribute to osmotic homeostasis.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2020-04-20T12:30:35Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0062236") +AnnotationAssertion(rdfs:label "ionocyte differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (protein localization to postsynapse) + +AnnotationAssertion(Annotation( "PMID:31189538") "Any process in which a protein is transported to, and/or maintained at the postsynapse, the part of a synapse that is part of the post-synaptic cell.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2020-04-20T13:58:43Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0062237") +AnnotationAssertion(rdfs:label "protein localization to postsynapse") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (intracellular protein transmembrane transport) + +AnnotationAssertion(Annotation( "GOC:isa_complete") "The directed movement of proteins in a cell, from one side of a membrane to another by means of some agent such as a transporter or pore.") +AnnotationAssertion( "intracellular membrane translocation of a protein") +AnnotationAssertion( "intracellular protein membrane transport") +AnnotationAssertion( "intracellular protein transport across a membrane") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0065002") +AnnotationAssertion(rdfs:comment "Note that this term is not intended for use in annotating lateral movement within membranes.") +AnnotationAssertion(rdfs:label "intracellular protein transmembrane transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + # Class: (protein-containing complex assembly) AnnotationAssertion(Annotation( "GOC:jl") "The aggregation, arrangement and bonding together of a set of macromolecules to form a protein-containing complex.") @@ -40120,8 +103780,20 @@ AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "protein-containing complex assembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (protein-DNA complex assembly) + +AnnotationAssertion(Annotation( "GOC:jl") "The aggregation, arrangement and bonding together of proteins and DNA molecules to form a protein-DNA complex.") +AnnotationAssertion(Annotation( "GOC:mah") "DNA-protein complex assembly") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0065004") +AnnotationAssertion(rdfs:label "protein-DNA complex assembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + # Class: (biological regulation) AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:isa_complete") Annotation( "GOC:mah") Annotation( "GOC:pr") Annotation( "GOC:vw") "Any process that modulates a measurable attribute of any biological process, quality or function.") @@ -40193,7 +103865,6 @@ AnnotationAssertion( "GO:0070051") AnnotationAssertion(rdfs:label "fibrinogen binding") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) # Class: (extracellular exosome) @@ -40212,8 +103883,58 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:0070091") AnnotationAssertion(rdfs:label "glucagon secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (regulation of glucagon secretion) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the regulated release of glucagon.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0070092") +AnnotationAssertion(rdfs:label "regulation of glucagon secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (negative regulation of glucagon secretion) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of glucagon.") +AnnotationAssertion( "down regulation of glucagon secretion") +AnnotationAssertion( "down-regulation of glucagon secretion") +AnnotationAssertion( "downregulation of glucagon secretion") +AnnotationAssertion( "inhibition of glucagon secretion") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0070093") +AnnotationAssertion(rdfs:label "negative regulation of glucagon secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of glucagon secretion) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of the regulated release of glucagon.") +AnnotationAssertion( "up regulation of glucagon secretion") +AnnotationAssertion( "up-regulation of glucagon secretion") +AnnotationAssertion( "upregulation of glucagon secretion") +AnnotationAssertion( "activation of glucagon secretion") +AnnotationAssertion( "stimulation of glucagon secretion") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0070094") +AnnotationAssertion(rdfs:label "positive regulation of glucagon secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (Kupffer's vesicle development) + +AnnotationAssertion(Annotation( "GOC:dgh") "The progression of the Kupffer's vesicle over time from its initial formation until its mature state. The Kupffer's vesicle is a small but distinctive epithelial sac containing fluid, located midventrally posterior to the yolk cell or its extension, and transiently present during most of the segmentation period.") +AnnotationAssertion(Annotation( "GOC:dgh") "KV development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0070121") +AnnotationAssertion(rdfs:label "Kupffer's vesicle development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + # Class: (tight junction) AnnotationAssertion(Annotation( "ISBN:0815332181") "A cell-cell junction that seals cells together in an epithelium in a way that prevents even small molecules from leaking from one side of the sheet to the other.") @@ -40234,12 +103955,267 @@ AnnotationAssertion( "anchoring junction") SubClassOf( ) +# Class: (regulation of biomineral tissue development) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of biomineral tissue development, the formation of hard tissues that consist mainly of inorganic compounds.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0070167") +AnnotationAssertion(rdfs:label "regulation of biomineral tissue development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (negative regulation of biomineral tissue development) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of biomineral tissue development, the formation of hard tissues that consist mainly of inorganic compounds.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0070168") +AnnotationAssertion(rdfs:label "negative regulation of biomineral tissue development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of biomineral tissue development) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of biomineral tissue development, the formation of hard tissues that consist mainly of inorganic compounds.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0070169") +AnnotationAssertion(rdfs:label "positive regulation of biomineral tissue development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of tooth mineralization) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of tooth mineralization, the deposition of calcium salts in tooth structures.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0070170") +AnnotationAssertion(rdfs:label "regulation of tooth mineralization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of tooth mineralization) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of tooth mineralization, the deposition of calcium salts in tooth structures.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0070171") +AnnotationAssertion(rdfs:label "negative regulation of tooth mineralization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of tooth mineralization) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of tooth mineralization, the deposition of calcium salts in tooth structures.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0070172") +AnnotationAssertion(rdfs:label "positive regulation of tooth mineralization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (chromosome organization involved in meiotic cell cycle) + +AnnotationAssertion(Annotation( "GOC:mah") "A process of chromosome organization that is involved in a meiotic cell cycle.") +AnnotationAssertion(Annotation( "GOC:mah") "chromosome organisation involved in meiosis") +AnnotationAssertion(Annotation( "GOC:mah") "meiotic chromosome organization") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0070192") +AnnotationAssertion(rdfs:label "chromosome organization involved in meiotic cell cycle") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (establishment of protein localization to chromosome) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mah") "The directed movement of a protein to a specific location on a chromosome.") +AnnotationAssertion(Annotation( "GOC:mah") "establishment of protein localisation to chromosome") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0070199") +AnnotationAssertion(rdfs:label "establishment of protein localization to chromosome") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of establishment of protein localization) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location.") +AnnotationAssertion(Annotation( "GOC:mah") "regulation of establishment of protein localisation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0070201") +AnnotationAssertion(rdfs:label "regulation of establishment of protein localization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of establishment of protein localization to chromosome) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location on a chromosome.") +AnnotationAssertion(Annotation( "GOC:mah") "regulation of establishment of protein localisation to chromosome") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0070202") +AnnotationAssertion(rdfs:label "regulation of establishment of protein localization to chromosome") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (lymphocyte apoptotic process) + +AnnotationAssertion(Annotation( "CL:0000542") Annotation( "GOC:add") Annotation( "GOC:mtg_apoptosis") Annotation( "ISBN:0781765196") "Any apoptotic process in a lymphocyte, a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin.") +AnnotationAssertion( "lymphocyte apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0070227") +AnnotationAssertion(rdfs:comment "Note that a lymphocyte is a cell of the B cell, T cell, or natural killer cell lineage (CL:0000542).") +AnnotationAssertion(rdfs:label "lymphocyte apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of lymphocyte apoptotic process) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:mtg_apoptosis") Annotation( "ISBN:0781765196") "Any process that modulates the occurrence or rate of lymphocyte death by apoptotic process.") +AnnotationAssertion( "regulation of lymphocyte apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0070228") +AnnotationAssertion(rdfs:comment "Note that a lymphocyte is a cell of the B cell, T cell, or natural killer cell lineage (CL:0000542).") +AnnotationAssertion(rdfs:label "regulation of lymphocyte apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of lymphocyte apoptotic process) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:mtg_apoptosis") Annotation( "ISBN:0781765196") "Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte death by apoptotic process.") +AnnotationAssertion(Annotation( "GOC:add") "down regulation of lymphocyte apoptosis") +AnnotationAssertion(Annotation( "GOC:add") "down-regulation of lymphocyte apoptosis") +AnnotationAssertion(Annotation( "GOC:add") "downregulation of lymphocyte apoptosis") +AnnotationAssertion(Annotation( "GOC:add") "inhibition of lymphocyte apoptosis") +AnnotationAssertion( "negative regulation of lymphocyte apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0070229") +AnnotationAssertion(rdfs:comment "Note that a lymphocyte is a cell of the B cell, T cell, or natural killer cell lineage (CL:0000542).") +AnnotationAssertion(rdfs:label "negative regulation of lymphocyte apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of lymphocyte apoptotic process) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:mtg_apoptosis") Annotation( "ISBN:0781765196") "Any process that activates or increases the frequency, rate or extent of lymphocyte death by apoptotic process.") +AnnotationAssertion(Annotation( "GOC:add") "up regulation of lymphocyte apoptosis") +AnnotationAssertion(Annotation( "GOC:add") "up-regulation of lymphocyte apoptosis") +AnnotationAssertion(Annotation( "GOC:add") "upregulation of lymphocyte apoptosis") +AnnotationAssertion(Annotation( "GOC:add") "activation of lymphocyte apoptosis") +AnnotationAssertion( "positive regulation of lymphocyte apoptosis") +AnnotationAssertion(Annotation( "GOC:add") "stimulation of lymphocyte apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0070230") +AnnotationAssertion(rdfs:comment "Note that a lymphocyte is a cell of the B cell, T cell, or natural killer cell lineage (CL:0000542).") +AnnotationAssertion(rdfs:label "positive regulation of lymphocyte apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (T cell apoptotic process) + +AnnotationAssertion(Annotation( "CL:0000084") Annotation( "GOC:add") Annotation( "GOC:mtg_apoptosis") Annotation( "ISBN:0781765196") "Any apoptotic process in a T cell, a type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex.") +AnnotationAssertion(Annotation( "GOC:add") "T lymphocyte apoptosis") +AnnotationAssertion(Annotation( "GOC:add") "T-cell apoptosis") +AnnotationAssertion(Annotation( "GOC:add") "T-lymphocyte apoptosis") +AnnotationAssertion(Annotation( "GOC:add") "programmed cell death of T cells by apoptosis") +AnnotationAssertion( "T cell apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0070231") +AnnotationAssertion(rdfs:label "T cell apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of T cell apoptotic process) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:mtg_apoptosis") Annotation( "ISBN:0781765196") "Any process that modulates the occurrence or rate of T cell death by apoptotic process.") +AnnotationAssertion(Annotation( "GOC:add") "regulation of T lymphocyte apoptosis") +AnnotationAssertion(Annotation( "GOC:add") "regulation of T-cell apoptosis") +AnnotationAssertion(Annotation( "GOC:add") "regulation of T-lymphocyte apoptosis") +AnnotationAssertion(Annotation( "GOC:add") "regulation of programmed cell death of T cells by apoptosis") +AnnotationAssertion( "regulation of T cell apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0070232") +AnnotationAssertion(rdfs:label "regulation of T cell apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of T cell apoptotic process) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:mtg_apoptosis") Annotation( "ISBN:0781765196") "Any process that stops, prevents, or reduces the frequency, rate or extent of T cell death by apoptotic process.") +AnnotationAssertion(Annotation( "GOC:add") "down regulation of T cell apoptosis") +AnnotationAssertion(Annotation( "GOC:add") "down-regulation of T cell apoptosis") +AnnotationAssertion(Annotation( "GOC:add") "downregulation of T cell apoptosis") +AnnotationAssertion(Annotation( "GOC:add") "negative regulation of T lymphocyte apoptosis") +AnnotationAssertion(Annotation( "GOC:add") "negative regulation of T-cell apoptosis") +AnnotationAssertion(Annotation( "GOC:add") "negative regulation of T-lymphocyte apoptosis") +AnnotationAssertion(Annotation( "GOC:add") "negative regulation of programmed cell death of T cells by apoptosis") +AnnotationAssertion(Annotation( "GOC:add") "inhibition of T cell apoptosis") +AnnotationAssertion( "negative regulation of T cell apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0070233") +AnnotationAssertion(rdfs:label "negative regulation of T cell apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of T cell apoptotic process) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:mtg_apoptosis") Annotation( "ISBN:0781765196") "Any process that activates or increases the frequency, rate or extent of T cell death by apoptotic process.") +AnnotationAssertion(Annotation( "GOC:add") "positive regulation of T lymphocyte apoptosis") +AnnotationAssertion(Annotation( "GOC:add") "positive regulation of T-cell apoptosis") +AnnotationAssertion(Annotation( "GOC:add") "positive regulation of T-lymphocyte apoptosis") +AnnotationAssertion(Annotation( "GOC:add") "positive regulation of programmed cell death of T cells by apoptosis") +AnnotationAssertion(Annotation( "GOC:add") "up regulation of T cell apoptosis") +AnnotationAssertion(Annotation( "GOC:add") "up-regulation of T cell apoptosis") +AnnotationAssertion(Annotation( "GOC:add") "upregulation of T cell apoptosis") +AnnotationAssertion(Annotation( "GOC:add") "activation of T cell apoptosis") +AnnotationAssertion( "positive regulation of T cell apoptosis") +AnnotationAssertion(Annotation( "GOC:add") "stimulation of T cell apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0070234") +AnnotationAssertion(rdfs:label "positive regulation of T cell apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (thymocyte apoptotic process) + +AnnotationAssertion(Annotation( "CL:0000893") Annotation( "GOC:add") Annotation( "GOC:mtg_apoptosis") Annotation( "ISBN:0781765196") "Any apoptotic process in a thymocyte, an immature T cell located in the thymus.") +AnnotationAssertion( "thymocyte apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:add") "immature T cell apoptosis") +AnnotationAssertion( "GO:0070242") +AnnotationAssertion(rdfs:comment "Note that a thymocyte is an immature T cell located in the thymus (CL:0000893).") +AnnotationAssertion(rdfs:label "thymocyte apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of thymocyte apoptotic process) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:mtg_apoptosis") Annotation( "ISBN:0781765196") "Any process that modulates the occurrence or rate of thymocyte death by apoptotic process.") +AnnotationAssertion( "regulation of thymocyte apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:add") "regulation of immature T cell apoptosis") +AnnotationAssertion( "GO:0070243") +AnnotationAssertion(rdfs:comment "Note that a thymocyte is an immature T cell located in the thymus (CL:0000893).") +AnnotationAssertion(rdfs:label "regulation of thymocyte apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of thymocyte apoptotic process) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:mtg_apoptosis") Annotation( "ISBN:0781765196") "Any process that stops, prevents, or reduces the frequency, rate or extent of thymocyte death by apoptotic process.") +AnnotationAssertion(Annotation( "GOC:add") "down regulation of thymocyte apoptosis") +AnnotationAssertion(Annotation( "GOC:add") "down-regulation of thymocyte apoptosis") +AnnotationAssertion(Annotation( "GOC:add") "downregulation of thymocyte apoptosis") +AnnotationAssertion(Annotation( "GOC:add") "inhibition of thymocyte apoptosis") +AnnotationAssertion( "negative regulation of thymocyte apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:add") "negative regulation of immature T cell apoptosis") +AnnotationAssertion( "GO:0070244") +AnnotationAssertion(rdfs:comment "Note that a thymocyte is an immature T cell located in the thymus (CL:0000893).") +AnnotationAssertion(rdfs:label "negative regulation of thymocyte apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of thymocyte apoptotic process) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:mtg_apoptosis") Annotation( "ISBN:0781765196") "Any process that activates or increases the frequency, rate or extent of thymocyte death by apoptotic process.") +AnnotationAssertion(Annotation( "GOC:add") "up regulation of thymocyte apoptosis") +AnnotationAssertion(Annotation( "GOC:add") "up-regulation of thymocyte apoptosis") +AnnotationAssertion(Annotation( "GOC:add") "upregulation of thymocyte apoptosis") +AnnotationAssertion(Annotation( "GOC:add") "activation of thymocyte apoptosis") +AnnotationAssertion( "positive regulation of thymocyte apoptosis") +AnnotationAssertion(Annotation( "GOC:add") "stimulation of thymocyte apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:add") "positive regulation of immature T cell apoptosis") +AnnotationAssertion( "GO:0070245") +AnnotationAssertion(rdfs:comment "Note that a thymocyte is an immature T cell located in the thymus (CL:0000893).") +AnnotationAssertion(rdfs:label "positive regulation of thymocyte apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (somatostatin secretion) AnnotationAssertion(Annotation( "GOC:mah") "The regulated release of somatostatin from secretory granules in the D cells of the pancreas.") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0070253") AnnotationAssertion(rdfs:label "somatostatin secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) # Class: (mucus secretion) @@ -40249,9 +104225,46 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:0070254") AnnotationAssertion(rdfs:label "mucus secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) +# Class: (regulation of mucus secretion) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that modulates the frequency, rate or extent of the regulated release of mucus from a cell or a tissue.") +AnnotationAssertion(Annotation( "GOC:add") "regulation of mucus production") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0070255") +AnnotationAssertion(rdfs:label "regulation of mucus secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of mucus secretion) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of mucus from a cell or a tissue.") +AnnotationAssertion(Annotation( "GOC:add") "negative regulation of mucus production") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0070256") +AnnotationAssertion(rdfs:label "negative regulation of mucus secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of mucus secretion) + +AnnotationAssertion(Annotation( "GOC:add") "Any process that activates or increases the frequency, rate or extent of the regulated release of mucus from a cell or a tissue.") +AnnotationAssertion(Annotation( "GOC:add") "positive regulation of mucus production") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0070257") +AnnotationAssertion(rdfs:label "positive regulation of mucus secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + # Class: (extracellular matrix constituent secretion) AnnotationAssertion(Annotation( "GOC:mah") "The controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell.") @@ -40263,6 +104276,16 @@ AnnotationAssertion(rdfs:label "extr SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (pigment cell development) + +AnnotationAssertion(Annotation( "GOC:cvs") "The process whose specific outcome is the progression of a pigment cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a pigment cell fate.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0070285") +AnnotationAssertion(rdfs:label "pigment cell development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (renal absorption) AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mah") Annotation( "GOC:yaf") "A renal system process in which water, ions, glucose and proteins are taken up from the collecting ducts, glomerulus and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures (e.g. protein absorption is observed in nephrocytes in Drosophila, see PMID:23264686).") @@ -40284,6 +104307,299 @@ AnnotationAssertion(rdfs:label "rena SubClassOf( ) SubClassOf( ) +# Class: (lens fiber cell differentiation) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "PMID:7693735") "The process in which a relatively unspecialized cell acquires specialized features of a lens fiber cell, any of the elongated, tightly packed cells that make up the bulk of the mature lens in the camera-type eye. The cytoplasm of a lens fiber cell is devoid of most intracellular organelles including the cell nucleus, and contains primarily crystallins, a group of water-soluble proteins expressed in vary large quantities.") +AnnotationAssertion(Annotation( "GOC:mah") "lens fibre cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0070306") +AnnotationAssertion(rdfs:label "lens fiber cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (lens fiber cell development) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "PMID:7693735") "The process whose specific outcome is the progression of a lens fiber cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a lens fiber cell fate. A lens fiber cell is any of the elongated, tightly packed cells that make up the bulk of the mature lens in a camera-type eye.") +AnnotationAssertion(Annotation( "GOC:mah") "lens fibre cell development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0070307") +AnnotationAssertion(rdfs:label "lens fiber cell development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (fat cell proliferation) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:sl") "The multiplication or reproduction of fat cells by cell division, resulting in the expansion of their population. A fat cell is an animal connective tissue cell specialized for the synthesis and storage of fat.") +AnnotationAssertion(Annotation( "GOC:sl") "adipocyte proliferation") +AnnotationAssertion(Annotation( "GOC:sl") "adipose cell proliferation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0070341") +AnnotationAssertion(rdfs:label "fat cell proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (brown fat cell proliferation) + +AnnotationAssertion(Annotation( "CL:0000449") Annotation( "GOC:mah") Annotation( "GOC:sl") "The multiplication or reproduction of brown fat cells by cell division, resulting in the expansion of their population. A brown fat cell is a fat cell found the thermogenic form of adipose tissue found in newborns of many species.") +AnnotationAssertion( ) +AnnotationAssertion(Annotation( "GOC:sl") "brown adipocyte proliferation") +AnnotationAssertion(Annotation( "GOC:sl") "brown adipose cell proliferation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0070342") +AnnotationAssertion(rdfs:label "brown fat cell proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses( ObjectSomeValuesFrom( )) + +# Class: (white fat cell proliferation) + +AnnotationAssertion(Annotation( "CL:0000448") Annotation( "GOC:mah") Annotation( "GOC:sl") "The multiplication or reproduction of white fat cells by cell division, resulting in the expansion of their population.") +AnnotationAssertion(Annotation( "GOC:sl") "white adipocyte proliferation") +AnnotationAssertion(Annotation( "GOC:sl") "white adipose cell proliferation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0070343") +AnnotationAssertion(rdfs:label "white fat cell proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of fat cell proliferation) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:sl") "Any process that modulates the frequency, rate or extent of fat cell proliferation.") +AnnotationAssertion(Annotation( "GOC:sl") "regulation of adipocyte proliferation") +AnnotationAssertion(Annotation( "GOC:sl") "regulation of adipose cell proliferation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0070344") +AnnotationAssertion(rdfs:label "regulation of fat cell proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of fat cell proliferation) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:sl") "Any process that stops or decreases the rate or extent of fat cell proliferation.") +AnnotationAssertion(Annotation( "GOC:mah") "down regulation of fat cell proliferation") +AnnotationAssertion(Annotation( "GOC:mah") "down-regulation of fat cell proliferation") +AnnotationAssertion(Annotation( "GOC:mah") "downregulation of fat cell proliferation") +AnnotationAssertion(Annotation( "GOC:sl") "negative regulation of adipocyte proliferation") +AnnotationAssertion(Annotation( "GOC:sl") "negative regulation of adipose cell proliferation") +AnnotationAssertion(Annotation( "GOC:mah") "inhibition of fat cell proliferation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0070345") +AnnotationAssertion(rdfs:label "negative regulation of fat cell proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of fat cell proliferation) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:sl") "Any process that activates or increases the rate or extent of fat cell proliferation.") +AnnotationAssertion(Annotation( "GOC:sl") "positive regulation of adipocyte proliferation") +AnnotationAssertion(Annotation( "GOC:sl") "positive regulation of adipose cell proliferation") +AnnotationAssertion(Annotation( "GOC:mah") "up regulation of fat cell proliferation") +AnnotationAssertion(Annotation( "GOC:mah") "up-regulation of fat cell proliferation") +AnnotationAssertion(Annotation( "GOC:mah") "upregulation of fat cell proliferation") +AnnotationAssertion(Annotation( "GOC:mah") "activation of fat cell proliferation") +AnnotationAssertion(Annotation( "GOC:mah") "stimulation of fat cell proliferation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0070346") +AnnotationAssertion(rdfs:label "positive regulation of fat cell proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of brown fat cell proliferation) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:sl") "Any process that modulates the frequency, rate or extent of brown fat cell proliferation.") +AnnotationAssertion(Annotation( "GOC:sl") "regulation of brown adipocyte proliferation") +AnnotationAssertion(Annotation( "GOC:sl") "regulation of brown adipose cell proliferation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0070347") +AnnotationAssertion(rdfs:label "regulation of brown fat cell proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of brown fat cell proliferation) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:sl") "Any process that stops or decreases the rate or extent of brown fat cell proliferation.") +AnnotationAssertion(Annotation( "GOC:mah") "down regulation of brown fat cell proliferation") +AnnotationAssertion(Annotation( "GOC:mah") "down-regulation of brown fat cell proliferation") +AnnotationAssertion(Annotation( "GOC:mah") "downregulation of brown fat cell proliferation") +AnnotationAssertion(Annotation( "GOC:sl") "negative regulation of brown adipocyte proliferation") +AnnotationAssertion(Annotation( "GOC:sl") "negative regulation of brown adipose cell proliferation") +AnnotationAssertion(Annotation( "GOC:mah") "inhibition of brown fat cell proliferation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0070348") +AnnotationAssertion(rdfs:label "negative regulation of brown fat cell proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of brown fat cell proliferation) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:sl") "Any process that activates or increases the rate or extent of brown fat cell proliferation.") +AnnotationAssertion(Annotation( "GOC:sl") "positive regulation of brown adipocyte proliferation") +AnnotationAssertion(Annotation( "GOC:sl") "positive regulation of brown adipose cell proliferation") +AnnotationAssertion(Annotation( "GOC:mah") "up regulation of brown fat cell proliferation") +AnnotationAssertion(Annotation( "GOC:mah") "up-regulation of brown fat cell proliferation") +AnnotationAssertion(Annotation( "GOC:mah") "upregulation of brown fat cell proliferation") +AnnotationAssertion(Annotation( "GOC:mah") "activation of brown fat cell proliferation") +AnnotationAssertion(Annotation( "GOC:mah") "stimulation of brown fat cell proliferation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0070349") +AnnotationAssertion(rdfs:label "positive regulation of brown fat cell proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of white fat cell proliferation) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:sl") "Any process that modulates the frequency, rate or extent of white fat cell proliferation.") +AnnotationAssertion(Annotation( "GOC:sl") "regulation of white adipocyte proliferation") +AnnotationAssertion(Annotation( "GOC:sl") "regulation of white adipose cell proliferation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0070350") +AnnotationAssertion(rdfs:label "regulation of white fat cell proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of white fat cell proliferation) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:sl") "Any process that stops or decreases the rate or extent of white fat cell proliferation.") +AnnotationAssertion(Annotation( "GOC:mah") "down regulation of white fat cell proliferation") +AnnotationAssertion(Annotation( "GOC:mah") "down-regulation of white fat cell proliferation") +AnnotationAssertion(Annotation( "GOC:mah") "downregulation of white fat cell proliferation") +AnnotationAssertion(Annotation( "GOC:sl") "negative regulation of white adipocyte proliferation") +AnnotationAssertion(Annotation( "GOC:sl") "negative regulation of white adipose cell proliferation") +AnnotationAssertion(Annotation( "GOC:mah") "inhibition of white fat cell proliferation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0070351") +AnnotationAssertion(rdfs:label "negative regulation of white fat cell proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of white fat cell proliferation) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:sl") "Any process that activates or increases the rate or extent of white fat cell proliferation.") +AnnotationAssertion(Annotation( "GOC:sl") "positive regulation of white adipocyte proliferation") +AnnotationAssertion(Annotation( "GOC:sl") "positive regulation of white adipose cell proliferation") +AnnotationAssertion(Annotation( "GOC:mah") "up regulation of white fat cell proliferation") +AnnotationAssertion(Annotation( "GOC:mah") "up-regulation of white fat cell proliferation") +AnnotationAssertion(Annotation( "GOC:mah") "upregulation of white fat cell proliferation") +AnnotationAssertion(Annotation( "GOC:mah") "activation of white fat cell proliferation") +AnnotationAssertion(Annotation( "GOC:mah") "stimulation of white fat cell proliferation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0070352") +AnnotationAssertion(rdfs:label "positive regulation of white fat cell proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (hepatocyte differentiation) + +AnnotationAssertion(Annotation( "CL:0000182") Annotation( "PMID:7588884") "The process in which a relatively unspecialized cell acquires the specialized features of a hepatocyte. A hepatocyte is specialized epithelial cell that is organized into interconnected plates called lobules, and is the main structural component of the liver.") +AnnotationAssertion(Annotation( "GOC:mah") "liver cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0070365") +AnnotationAssertion(rdfs:label "hepatocyte differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (regulation of hepatocyte differentiation) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:sl") "Any process that modulates the frequency, rate or extent of hepatocyte differentiation.") +AnnotationAssertion(Annotation( "GOC:sl") "regulation of liver cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0070366") +AnnotationAssertion(rdfs:label "regulation of hepatocyte differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of hepatocyte differentiation) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:sl") "Any process that stops or decreases the rate or extent of hepatocyte differentiation.") +AnnotationAssertion(Annotation( "GOC:mah") "down regulation of hepatocyte differentiation") +AnnotationAssertion(Annotation( "GOC:mah") "down-regulation of hepatocyte differentiation") +AnnotationAssertion(Annotation( "GOC:mah") "downregulation of hepatocyte differentiation") +AnnotationAssertion(Annotation( "GOC:sl") "negative regulation of liver cell differentiation") +AnnotationAssertion(Annotation( "GOC:mah") "inhibition of hepatocyte differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0070367") +AnnotationAssertion(rdfs:label "negative regulation of hepatocyte differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (positive regulation of hepatocyte differentiation) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:sl") "Any process that activates or increases the rate or extent of hepatocyte differentiation.") +AnnotationAssertion(Annotation( "GOC:sl") "positive regulation of liver cell differentiation") +AnnotationAssertion(Annotation( "GOC:mah") "up regulation of hepatocyte differentiation") +AnnotationAssertion(Annotation( "GOC:mah") "up-regulation of hepatocyte differentiation") +AnnotationAssertion(Annotation( "GOC:mah") "upregulation of hepatocyte differentiation") +AnnotationAssertion(Annotation( "GOC:mah") "activation of hepatocyte differentiation") +AnnotationAssertion(Annotation( "GOC:mah") "stimulation of hepatocyte differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0070368") +AnnotationAssertion(rdfs:label "positive regulation of hepatocyte differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (exocytic vesicle) + +AnnotationAssertion(Annotation( "GOC:kad") Annotation( "GOC:mah") "A transport vesicle that mediates transport from an intracellular compartment to the plasma membrane, and fuses with the plasma membrane to release various cargo molecules, such as proteins or hormones, by exocytosis.") +AnnotationAssertion( "exocytic constitutive secretory pathway transport vesicle") +AnnotationAssertion(Annotation( "GOC:kad") "exocytotic vesicle") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0070382") +AnnotationAssertion(rdfs:label "exocytic vesicle") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (Harderian gland development) + +AnnotationAssertion(Annotation( "GOC:hjd") Annotation( "PMID:16856596") Annotation( "PMID:7559104") "The process whose specific outcome is the progression of the Harderian gland over time, from its formation to the mature structure. The Harderian gland is an anterior orbital structure usually associated with the nictitating membrane, and produces and secretes a variety of substances to the eye, depending upon the species.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0070384") +AnnotationAssertion(rdfs:comment "Note that the Harderian gland is found in all terrestrial vertebrate groups, including amphibia, reptiles, birds, and mammals. However, it appears to be absent in certain mammals such as bats, cows, horses, and higher primates. Though largely absent in the adult human, it is present in the fetal and neonatal stages.") +AnnotationAssertion(rdfs:label "Harderian gland development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (ammonium ion binding) + +AnnotationAssertion(Annotation( "CHEBI:28938") Annotation( "GOC:ecd") "Binding to ammonium ions (NH4+).") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "ammonium binding") +AnnotationAssertion( "GO:0070405") +AnnotationAssertion(rdfs:label "ammonium ion binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (oligodendrocyte progenitor proliferation) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:sl") Annotation( "PMID:15504915") "The multiplication or reproduction of oligodendrocyte progenitor cells by cell division, resulting in the expansion of their population. Oligodendrocyte progenitors give rise to oligodendrocytes, which form the insulating myelin sheath of axons in the central nervous system.") +AnnotationAssertion(Annotation( "GOC:mah") "oligodendrocyte precursor proliferation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0070444") +AnnotationAssertion(rdfs:label "oligodendrocyte progenitor proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (regulation of oligodendrocyte progenitor proliferation) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:sl") "Any process that modulates the frequency, rate or extent of oligodendrocyte progenitor proliferation.") +AnnotationAssertion(Annotation( "GOC:mah") "regulation of oligodendrocyte precursor proliferation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0070445") +AnnotationAssertion(rdfs:label "regulation of oligodendrocyte progenitor proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of oligodendrocyte progenitor proliferation) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:sl") "Any process that stops or decreases the rate or extent of oligodendrocyte progenitor proliferation.") +AnnotationAssertion(Annotation( "GOC:mah") "negative regulation of oligodendrocyte precursor proliferation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0070446") +AnnotationAssertion(rdfs:label "negative regulation of oligodendrocyte progenitor proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (positive regulation of oligodendrocyte progenitor proliferation) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:sl") "Any process that activates or increases the rate or extent of oligodendrocyte progenitor proliferation.") +AnnotationAssertion(Annotation( "GOC:mah") "positive regulation of oligodendrocyte precursor proliferation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0070447") +AnnotationAssertion(rdfs:label "positive regulation of oligodendrocyte progenitor proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + # Class: (cell hair) AnnotationAssertion(Annotation( "PMID:11526084") "A long, thin cell projection that contains F-actin and tubulin, with microtubules centrally located and F-actin peripherally located.") @@ -40295,6 +104611,15 @@ AnnotationAssertion( "cell hair") SubClassOf( ) +# Class: (prolactin secretion) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "ISBN:0198506732") "The regulated release of prolactin, a peptide hormone that stimulates lactation, from secretory granules in the anterior pituitary.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0070459") +AnnotationAssertion(rdfs:label "prolactin secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + # Class: (response to oxygen levels) AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of oxygen.") @@ -40313,6 +104638,83 @@ AnnotationAssertion(rdfs:label "dete SubClassOf( ) SubClassOf( ) +# Class: (regulation of microtubule cytoskeleton organization) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins.") +AnnotationAssertion(Annotation( "GOC:mah") "regulation of microtubule cytoskeleton organisation") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "regulation of microtubule dynamics") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0070507") +AnnotationAssertion(rdfs:label "regulation of microtubule cytoskeleton organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (response to fatty acid) + +AnnotationAssertion(Annotation( "GOC:lp") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fatty acid stimulus.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0070542") +AnnotationAssertion(rdfs:label "response to fatty acid") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (protein secretion by platelet) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mah") "The regulated release of proteins by a platelet or group of platelets.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2009-04-09T02:38:05Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0070560") +AnnotationAssertion(rdfs:label "protein secretion by platelet") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (calcium ion transmembrane transport) + +AnnotationAssertion(Annotation( "GOC:mah") "A process in which a calcium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2009-04-28T10:44:09Z") +AnnotationAssertion( "calcium ion membrane transport") +AnnotationAssertion(Annotation( "GOC:mah") "transmembrane calcium transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0070588") +AnnotationAssertion(rdfs:comment "Note that this term is not intended for use in annotating lateral movement within membranes.") +AnnotationAssertion(rdfs:label "calcium ion transmembrane transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of protein processing) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of protein processing, a protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2009-04-29T02:49:14Z") +AnnotationAssertion( "GO:0010953") +AnnotationAssertion( "regulation of protein maturation by peptide bond cleavage") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0070613") +AnnotationAssertion(rdfs:label "regulation of protein processing") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (transepithelial transport) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:yaf") Annotation( "ISBN:0716731363") "The directed movement of a substance from one side of an epithelium to the other.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2009-05-06T03:31:02Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0070633") +AnnotationAssertion(rdfs:label "transepithelial transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (transepithelial ammonium transport) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:yaf") "The directed movement of ammonium ions from one side of an epithelium to the other.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2009-05-06T03:34:43Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0070634") +AnnotationAssertion(rdfs:label "transepithelial ammonium transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (leukocyte proliferation) AnnotationAssertion(Annotation( "GOC:add") "The expansion of a leukocyte population by cell division.") @@ -40321,10 +104723,54 @@ AnnotationAssertion( AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0070661") AnnotationAssertion(rdfs:label "leukocyte proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectAllValuesFrom( )) +# Class: (regulation of leukocyte proliferation) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of leukocyte proliferation.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2009-05-28T05:30:39Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0070663") +AnnotationAssertion(rdfs:label "regulation of leukocyte proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (negative regulation of leukocyte proliferation) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of leukocyte proliferation.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2009-05-28T05:34:50Z") +AnnotationAssertion(Annotation( "GOC:mah") "down regulation of leukocyte proliferation") +AnnotationAssertion(Annotation( "GOC:mah") "down-regulation of leukocyte proliferation") +AnnotationAssertion(Annotation( "GOC:mah") "downregulation of leukocyte proliferation") +AnnotationAssertion(Annotation( "GOC:mah") "inhibition of leukocyte proliferation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0070664") +AnnotationAssertion(rdfs:label "negative regulation of leukocyte proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (positive regulation of leukocyte proliferation) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of leukocyte proliferation.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2009-05-28T05:36:46Z") +AnnotationAssertion(Annotation( "GOC:mah") "up regulation of leukocyte proliferation") +AnnotationAssertion(Annotation( "GOC:mah") "up-regulation of leukocyte proliferation") +AnnotationAssertion(Annotation( "GOC:mah") "upregulation of leukocyte proliferation") +AnnotationAssertion(Annotation( "GOC:mah") "activation of leukocyte proliferation") +AnnotationAssertion(Annotation( "GOC:mah") "stimulation of leukocyte proliferation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0070665") +AnnotationAssertion(rdfs:label "positive regulation of leukocyte proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + # Class: (cellular macromolecule localization) AnnotationAssertion(Annotation( "GOC:mah") "Any process in which a macromolecule is transported to, and/or maintained in, a specific location at the level of a cell. Localization at the cellular level encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell.") @@ -40337,6 +104783,144 @@ AnnotationAssertion(rdfs:label "cell SubClassOf( ) SubClassOf( ) +# Class: (bicellular tight junction assembly) + +AnnotationAssertion(Annotation( "GOC:mah") "The aggregation, arrangement and bonding together of a set of components to form a tight junction, an occluding cell-cell junction that is composed of a branching network of sealing strands that completely encircles the apical end of each cell in an epithelial sheet.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2009-07-23T04:32:38Z") +AnnotationAssertion(Annotation( "GOC:mah") "tight junction formation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0070830") +AnnotationAssertion(rdfs:label "bicellular tight junction assembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (basement membrane assembly) + +AnnotationAssertion(Annotation( "GOC:mah") "The aggregation, arrangement and bonding together of a set of components to form a basement membrane, a part of the extracellular region that consists of a thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2009-07-23T05:01:51Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0070831") +AnnotationAssertion(rdfs:comment "Note that this term has no relationship to 'membrane assembly ; GO:0071709' because the basement membrane is not a lipid bilayer.") +AnnotationAssertion(rdfs:label "basement membrane assembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (growth factor receptor binding) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:vw") "Binding to a growth factor receptor.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2009-08-07T11:23:02Z") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0070851") +AnnotationAssertion(rdfs:label "growth factor receptor binding") +SubClassOf( ) + +# Class: (regulation of bile acid biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2009-08-14T03:09:02Z") +AnnotationAssertion(Annotation( "GOC:mah") "regulation of bile acid anabolism") +AnnotationAssertion(Annotation( "GOC:mah") "regulation of bile acid biosynthesis") +AnnotationAssertion(Annotation( "GOC:mah") "regulation of bile acid formation") +AnnotationAssertion(Annotation( "GOC:mah") "regulation of bile acid synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0070857") +AnnotationAssertion(rdfs:label "regulation of bile acid biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of bile acid biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2009-08-14T03:16:40Z") +AnnotationAssertion(Annotation( "GOC:mah") "down regulation of bile acid biosynthetic process") +AnnotationAssertion(Annotation( "GOC:mah") "down-regulation of bile acid biosynthetic process") +AnnotationAssertion(Annotation( "GOC:mah") "downregulation of bile acid biosynthetic process") +AnnotationAssertion(Annotation( "GOC:mah") "negative regulation of bile acid anabolism") +AnnotationAssertion(Annotation( "GOC:mah") "negative regulation of bile acid biosynthesis") +AnnotationAssertion(Annotation( "GOC:mah") "negative regulation of bile acid formation") +AnnotationAssertion(Annotation( "GOC:mah") "negative regulation of bile acid synthesis") +AnnotationAssertion(Annotation( "GOC:mah") "inhibition of bile acid biosynthetic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0070858") +AnnotationAssertion(rdfs:label "negative regulation of bile acid biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of bile acid biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2009-08-14T03:22:58Z") +AnnotationAssertion(Annotation( "GOC:mah") "positive regulation of bile acid anabolism") +AnnotationAssertion(Annotation( "GOC:mah") "positive regulation of bile acid biosynthesis") +AnnotationAssertion(Annotation( "GOC:mah") "positive regulation of bile acid formation") +AnnotationAssertion(Annotation( "GOC:mah") "positive regulation of bile acid synthesis") +AnnotationAssertion(Annotation( "GOC:mah") "up regulation of bile acid biosynthetic process") +AnnotationAssertion(Annotation( "GOC:mah") "up-regulation of bile acid biosynthetic process") +AnnotationAssertion(Annotation( "GOC:mah") "upregulation of bile acid biosynthetic process") +AnnotationAssertion(Annotation( "GOC:mah") "activation of bile acid biosynthetic process") +AnnotationAssertion(Annotation( "GOC:mah") "stimulation of bile acid biosynthetic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0070859") +AnnotationAssertion(rdfs:label "positive regulation of bile acid biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of glycogen metabolic process) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving glycogen.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2009-08-20T02:44:53Z") +AnnotationAssertion(Annotation( "GOC:mah") "regulation of glycogen metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0070873") +AnnotationAssertion(rdfs:label "regulation of glycogen metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of glycogen metabolic process) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving glycogen.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2009-08-20T02:50:41Z") +AnnotationAssertion(Annotation( "GOC:mah") "negative regulation of glycogen metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0070874") +AnnotationAssertion(rdfs:label "negative regulation of glycogen metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of glycogen metabolic process) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving glycogen.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2009-08-20T02:53:55Z") +AnnotationAssertion(Annotation( "GOC:mah") "positive regulation of glycogen metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0070875") +AnnotationAssertion(rdfs:label "positive regulation of glycogen metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + # Class: (cellular response to chemical stimulus) AnnotationAssertion(Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus.") @@ -40350,6 +104934,590 @@ AnnotationAssertion(rdfs:label "cell SubClassOf( ) SubClassOf( ) +# Class: (organelle assembly) + +AnnotationAssertion(Annotation( "GOC:mah") "The aggregation, arrangement and bonding together of a set of components to form an organelle. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2009-09-15T03:00:51Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0070925") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "organelle assembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (bone maturation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:mah") "A developmental process, independent of morphogenetic (shape) change, that is required for bone to attain its fully functional state.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2009-10-05T04:35:31Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0070977") +AnnotationAssertion(rdfs:label "bone maturation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (regulation of phospholipid biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phospholipids.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2009-11-04T03:05:11Z") +AnnotationAssertion(Annotation( "GOC:mah") "regulation of phospholipid anabolism") +AnnotationAssertion(Annotation( "GOC:mah") "regulation of phospholipid biosynthesis") +AnnotationAssertion(Annotation( "GOC:mah") "regulation of phospholipid formation") +AnnotationAssertion(Annotation( "GOC:mah") "regulation of phospholipid synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0071071") +AnnotationAssertion(rdfs:label "regulation of phospholipid biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of phospholipid biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phospholipids.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2009-11-04T03:14:08Z") +AnnotationAssertion(Annotation( "GOC:mah") "down regulation of phospholipid biosynthetic process") +AnnotationAssertion(Annotation( "GOC:ma") "down-regulation of phospholipid biosynthetic process") +AnnotationAssertion(Annotation( "GOC:mah") "downregulation of phospholipid biosynthetic process") +AnnotationAssertion(Annotation( "GOC:mah") "negative regulation of phospholipid anabolism") +AnnotationAssertion(Annotation( "GOC:mah") "negative regulation of phospholipid biosynthesis") +AnnotationAssertion(Annotation( "GOC:mah") "negative regulation of phospholipid formation") +AnnotationAssertion(Annotation( "GOC:mah") "negative regulation of phospholipid synthesis") +AnnotationAssertion(Annotation( "GOC:mah") "inhibition of phospholipid biosynthetic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0071072") +AnnotationAssertion(rdfs:label "negative regulation of phospholipid biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of phospholipid biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phospholipids.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2009-11-04T03:18:51Z") +AnnotationAssertion(Annotation( "GOC:mah") "positive regulation of phospholipid anabolism") +AnnotationAssertion(Annotation( "GOC:mah") "positive regulation of phospholipid biosynthesis") +AnnotationAssertion(Annotation( "GOC:mah") "positive regulation of phospholipid formation") +AnnotationAssertion(Annotation( "GOC:mah") "positive regulation of phospholipid synthesis") +AnnotationAssertion(Annotation( "GOC:mah") "up regulation of phospholipid biosynthetic process") +AnnotationAssertion(Annotation( "GOC:mah") "up-regulation of phospholipid biosynthetic process") +AnnotationAssertion(Annotation( "GOC:mah") "upregulation of phospholipid biosynthetic process") +AnnotationAssertion(Annotation( "GOC:mah") "activation of phospholipid biosynthetic process") +AnnotationAssertion(Annotation( "GOC:mah") "stimulation of phospholipid biosynthetic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0071073") +AnnotationAssertion(rdfs:label "positive regulation of phospholipid biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (superior temporal gyrus development) + +AnnotationAssertion(Annotation( "FMA:61905") Annotation( "GOC:BHF") Annotation( "GOC:mah") Annotation( "PMID:11484000") "The process whose specific outcome is the progression of the superior temporal gyrus over time, from its formation to the mature structure. The superior temporal gyrus is a portion of the cerebral cortex that extends from the lateral sulcus to the superior temporal sulcus.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2009-11-12T02:19:23Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0071109") +AnnotationAssertion(rdfs:label "superior temporal gyrus development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (protein localization to chromatin) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process in which a protein is transported to, or maintained at, a part of a chromosome that is organized into chromatin.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2009-11-20T11:51:20Z") +AnnotationAssertion(Annotation( "GOC:mah") "protein localisation to chromatin") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0071168") +AnnotationAssertion(rdfs:label "protein localization to chromatin") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (establishment of protein localization to chromatin) + +AnnotationAssertion(Annotation( "GOC:mah") "The directed movement of a protein to a part of a chromosome that is organized into chromatin.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2009-11-20T11:52:43Z") +AnnotationAssertion(Annotation( "GOC:mah") "establishment of protein localisation to chromatin") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0071169") +AnnotationAssertion(rdfs:label "establishment of protein localization to chromatin") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (cellular response to abiotic stimulus) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abiotic (non-living) stimulus.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2009-12-03T01:02:11Z") +AnnotationAssertion(Annotation( "GOC:mah") "cellular response to abiotic stress") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0071214") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.") +AnnotationAssertion(rdfs:label "cellular response to abiotic stimulus") +SubClassOf( ) +SubClassOf( ) + +# Class: (cellular response to amino acid stimulus) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2009-12-03T02:08:11Z") +AnnotationAssertion(Annotation( "GOC:mah") "cellular response to amino acid") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0071230") +AnnotationAssertion(rdfs:label "cellular response to amino acid stimulus") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (cellular response to inorganic substance) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inorganic substance stimulus.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2009-12-03T02:35:49Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0071241") +AnnotationAssertion(rdfs:label "cellular response to inorganic substance") +SubClassOf( ) +SubClassOf( ) + +# Class: (cellular response to ammonium ion) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000071") Annotation( "PMID:23509267") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ammonium stimulus.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2009-12-03T02:39:40Z") +AnnotationAssertion( "GO:1903718") +AnnotationAssertion( "cellular response to ammonia") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0071242") +AnnotationAssertion(rdfs:label "cellular response to ammonium ion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (cellular response to carbon dioxide) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbon dioxide (CO2) stimulus.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2009-12-03T02:41:21Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0071244") +AnnotationAssertion(rdfs:label "cellular response to carbon dioxide") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (cellular response to metal ion) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metal ion stimulus.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2009-12-03T02:46:31Z") +AnnotationAssertion(Annotation( "GOC:mah") "cellular response to metal") +AnnotationAssertion(Annotation( "GOC:mah") "cellular response to heavy metal") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0071248") +AnnotationAssertion(rdfs:label "cellular response to metal ion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (cellular response to calcium ion) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2009-12-10T03:55:01Z") +AnnotationAssertion(Annotation( "GOC:mah") "cellular response to Ca2+ ion") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0071277") +AnnotationAssertion(rdfs:label "cellular response to calcium ion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (cellular response to iron ion) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron ion stimulus.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2009-12-10T03:57:22Z") +AnnotationAssertion(Annotation( "GOC:mah") "cellular response to iron") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0071281") +AnnotationAssertion(rdfs:label "cellular response to iron ion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (cellular response to organic substance) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic substance stimulus.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2009-12-10T04:46:04Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0071310") +AnnotationAssertion(rdfs:label "cellular response to organic substance") +SubClassOf( ) +SubClassOf( ) + +# Class: (cellular response to acetate) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetate stimulus.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2009-12-10T04:48:16Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0071311") +AnnotationAssertion(rdfs:label "cellular response to acetate") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (cellular response to alkaloid) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkaloid stimulus. Alkaloids are a large group of nitrogenous substances found in naturally in plants, many of which have extracts that are pharmacologically active.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2009-12-10T04:50:58Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0071312") +AnnotationAssertion(rdfs:label "cellular response to alkaloid") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (cellular response to ATP) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ATP (adenosine 5'-triphosphate) stimulus.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2009-12-10T05:09:47Z") +AnnotationAssertion(Annotation( "GOC:mah") "cellular response to adenosine 5'-triphosphate") +AnnotationAssertion(Annotation( "GOC:mah") "cellular response to adenosine triphosphate") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0071318") +AnnotationAssertion(rdfs:label "cellular response to ATP") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (cellular response to carbohydrate stimulus) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbohydrate stimulus.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2009-12-10T05:13:33Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0071322") +AnnotationAssertion(rdfs:label "cellular response to carbohydrate stimulus") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (cellular response to chitin) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chitin stimulus.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2009-12-10T05:25:54Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0071323") +AnnotationAssertion(rdfs:label "cellular response to chitin") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (cellular response to monosaccharide stimulus) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monosaccharide stimulus.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2009-12-10T05:27:18Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0071326") +AnnotationAssertion(rdfs:label "cellular response to monosaccharide stimulus") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (cellular response to hexose stimulus) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hexose stimulus.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2009-12-10T05:37:00Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0071331") +AnnotationAssertion(rdfs:label "cellular response to hexose stimulus") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (cellular response to glucose stimulus) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucose stimulus.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2009-12-10T05:38:03Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0071333") +AnnotationAssertion(rdfs:label "cellular response to glucose stimulus") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (cellular response to cytokine stimulus) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokine stimulus.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2009-12-11T02:41:12Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0071345") +AnnotationAssertion(rdfs:label "cellular response to cytokine stimulus") +SubClassOf( ) +SubClassOf( ) + +# Class: (cellular response to peptide hormone stimulus) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide hormone stimulus. A peptide hormone is any of a class of peptides that are secreted into the blood stream and have endocrine functions in living animals.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2009-12-11T03:24:18Z") +AnnotationAssertion(Annotation( "GOC:mah") "cellular response to polypeptide hormone stimulus") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0071375") +AnnotationAssertion(rdfs:label "cellular response to peptide hormone stimulus") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (cellular response to glucagon stimulus) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucagon stimulus.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2009-12-11T03:25:07Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0071377") +AnnotationAssertion(rdfs:label "cellular response to glucagon stimulus") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (cellular response to steroid hormone stimulus) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a steroid hormone stimulus.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2009-12-11T03:49:02Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0071383") +AnnotationAssertion(rdfs:label "cellular response to steroid hormone stimulus") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (cellular response to corticosteroid stimulus) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticosteroid hormone stimulus. A corticosteroid is a steroid hormone that is produced in the adrenal cortex. Corticosteroids are involved in a wide range of physiologic systems such as stress response, immune response and regulation of inflammation, carbohydrate metabolism, protein catabolism, blood electrolyte levels, and behavior. They include glucocorticoids and mineralocorticoids.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2009-12-11T03:52:07Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0071384") +AnnotationAssertion(rdfs:label "cellular response to corticosteroid stimulus") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (cellular response to glucocorticoid stimulus) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucocorticoid stimulus. Glucocorticoids are hormonal C21 corticosteroids synthesized from cholesterol with the ability to bind with the cortisol receptor and trigger similar effects. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2009-12-11T03:53:56Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0071385") +AnnotationAssertion(rdfs:label "cellular response to glucocorticoid stimulus") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (cellular response to mineralocorticoid stimulus) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mineralocorticoid stimulus. Mineralocorticoids are hormonal C21 corticosteroids synthesized from cholesterol and characterized by their similarity to aldosterone. Mineralocorticoids act primarily on water and electrolyte balance.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2009-12-11T03:59:02Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0071389") +AnnotationAssertion(rdfs:label "cellular response to mineralocorticoid stimulus") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (cellular response to progesterone stimulus) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a progesterone stimulus.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2009-12-11T04:11:13Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0071393") +AnnotationAssertion(rdfs:label "cellular response to progesterone stimulus") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (cellular response to testosterone stimulus) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a testosterone stimulus.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2009-12-11T04:11:29Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0071394") +AnnotationAssertion(rdfs:label "cellular response to testosterone stimulus") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (cellular response to lipid) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid stimulus.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2009-12-11T04:37:10Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0071396") +AnnotationAssertion(rdfs:label "cellular response to lipid") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (cellular response to fatty acid) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fatty acid stimulus.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2009-12-11T04:39:56Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0071398") +AnnotationAssertion(rdfs:label "cellular response to fatty acid") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (cellular response to organic cyclic compound) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2009-12-14T02:55:58Z") +AnnotationAssertion(Annotation( "GOC:mah") "cellular response to organic cyclic substance") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0071407") +AnnotationAssertion(rdfs:label "cellular response to organic cyclic compound") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (cellular response to organonitrogen compound) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organonitrogen stimulus. An organonitrogen compound is formally a compound containing at least one carbon-nitrogen bond.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2009-12-14T04:07:27Z") +AnnotationAssertion(Annotation( "GOC:mah") "cellular response to organic nitrogen") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0071417") +AnnotationAssertion(rdfs:label "cellular response to organonitrogen compound") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (cellular response to amine stimulus) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amine stimulus. An amine is a compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2009-12-14T04:08:17Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0071418") +AnnotationAssertion(rdfs:label "cellular response to amine stimulus") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (cellular response to histamine) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a histamine stimulus. Histamine, the biogenic amine 2-(1H-imidazol-4-yl)ethanamine, is involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2009-12-14T04:09:25Z") +AnnotationAssertion(Annotation( "GOC:mah") "cellular response to histamine stimulus") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0071420") +AnnotationAssertion(rdfs:label "cellular response to histamine") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (hematopoietic stem cell proliferation) + +AnnotationAssertion(Annotation( "CL:0000037") Annotation( "GOC:BHF") Annotation( "GOC:add") Annotation( "GOC:mah") Annotation( "GOC:rl") "The expansion of a hematopoietic stem cell population by cell division. A hematopoietic stem cell is a stem cell from which all cells of the lymphoid and myeloid lineages develop.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2009-12-16T10:22:52Z") +AnnotationAssertion( "hemopoietic stem cell proliferation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0071425") +AnnotationAssertion(rdfs:label "hematopoietic stem cell proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cellular response to water stimulus) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of water.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2009-12-18T11:32:44Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0071462") +AnnotationAssertion(rdfs:label "cellular response to water stimulus") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (cellular response to endogenous stimulus) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus arising within the organism.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2009-12-18T02:25:40Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0071495") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.") +AnnotationAssertion(rdfs:label "cellular response to endogenous stimulus") +SubClassOf( ) + +# Class: (dopaminergic neuron differentiation) + +AnnotationAssertion(Annotation( "GOC:rph") "The process in which a neuroblast acquires the specialized structural and functional features of a dopaminergic neuron, a neuron that secretes dopamine.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-01-12T02:28:44Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0071542") +AnnotationAssertion(rdfs:label "dopaminergic neuron differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (cement gland development) + +AnnotationAssertion(Annotation( "GOC:bf") "The process whose specific outcome is the progression of the cement gland over time, from its formation to the mature structure. The cement gland is a simple mucus-secreting organ positioned at the anterior of amphibious embryos. The cement gland attaches the newly hatched embryo to a support before the hatchling can swim well or feed.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-01-20T04:31:04Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0071570") +AnnotationAssertion(rdfs:label "cement gland development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (otic vesicle development) + +AnnotationAssertion(Annotation( "GOC:mah") "The process whose specific outcome is the progression of the otic vesicle over time, from its formation to the mature structure. The otic vesicle is a transient embryonic structure formed during development of the vertebrate inner ear.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-02-04T04:07:17Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0071599") +AnnotationAssertion(rdfs:label "otic vesicle development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (otic vesicle morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mah") "The process in which the anatomical structures of the otic vesicle are generated and organized. The otic vesicle is a transient embryonic structure formed during development of the vertebrate inner ear.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-02-04T04:07:27Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0071600") +AnnotationAssertion(rdfs:label "otic vesicle morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (granulocyte chemotaxis) + +AnnotationAssertion(Annotation( "GOC:rph") "The movement of a granulocyte in response to an external stimulus.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-02-09T04:08:17Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0071621") +AnnotationAssertion(rdfs:label "granulocyte chemotaxis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of granulocyte chemotaxis) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the rate, frequency or extent of granulocyte chemotaxis. Granulocyte chemotaxis is the movement of a granulocyte in response to an external stimulus.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-02-09T04:09:24Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0071622") +AnnotationAssertion(rdfs:label "regulation of granulocyte chemotaxis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of granulocyte chemotaxis) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that decreases the rate, frequency or extent of granulocyte chemotaxis. Granulocyte chemotaxis is the movement of a granulocyte in response to an external stimulus.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-02-09T04:13:19Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0071623") +AnnotationAssertion(rdfs:label "negative regulation of granulocyte chemotaxis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of granulocyte chemotaxis) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that increases the rate, frequency or extent of granulocyte chemotaxis. Granulocyte chemotaxis is the movement of a granulocyte in response to an external stimulus.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-02-09T04:15:36Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0071624") +AnnotationAssertion(rdfs:label "positive regulation of granulocyte chemotaxis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (vocalization behavior) AnnotationAssertion(Annotation( "GOC:mah") "The behavior in which an organism produces sounds by a mechanism involving its respiratory system.") @@ -40372,6 +105540,107 @@ AnnotationAssertion( "mastication") SubClassOf( ) +# Class: (smooth muscle cell chemotaxis) + +AnnotationAssertion(Annotation( "GOC:mah") "The directed movement of a smooth muscle cell in response to an external stimulus.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-02-16T01:32:59Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0071670") +AnnotationAssertion(rdfs:label "smooth muscle cell chemotaxis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of smooth muscle cell chemotaxis) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate, or extent of smooth muscle cell chemotaxis.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-02-16T01:42:03Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0071671") +AnnotationAssertion(rdfs:label "regulation of smooth muscle cell chemotaxis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of smooth muscle cell chemotaxis) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate, or extent of smooth muscle cell chemotaxis.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-02-16T01:44:28Z") +AnnotationAssertion(Annotation( "GOC:mah") "down regulation of smooth muscle cell chemotaxis") +AnnotationAssertion(Annotation( "GOC:mah") "down-regulation of smooth muscle cell chemotaxis") +AnnotationAssertion(Annotation( "GOC:mah") "downregulation of smooth muscle cell chemotaxis") +AnnotationAssertion(Annotation( "GOC:mah") "inhibition of smooth muscle cell chemotaxis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0071672") +AnnotationAssertion(rdfs:label "negative regulation of smooth muscle cell chemotaxis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of smooth muscle cell chemotaxis) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate, or extent of smooth muscle cell chemotaxis.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-02-16T01:48:14Z") +AnnotationAssertion(Annotation( "GOC:mah") "up regulation of smooth muscle cell chemotaxis") +AnnotationAssertion(Annotation( "GOC:mah") "up-regulation of smooth muscle cell chemotaxis") +AnnotationAssertion(Annotation( "GOC:mah") "upregulation of smooth muscle cell chemotaxis") +AnnotationAssertion(Annotation( "GOC:mah") "activation of smooth muscle cell chemotaxis") +AnnotationAssertion(Annotation( "GOC:mah") "stimulation of smooth muscle cell chemotaxis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0071673") +AnnotationAssertion(rdfs:label "positive regulation of smooth muscle cell chemotaxis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (mononuclear cell migration) + +AnnotationAssertion(Annotation( "GOC:mah") "The movement of a mononuclear cell within or between different tissues and organs of the body.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-02-16T02:11:00Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0071674") +AnnotationAssertion(rdfs:label "mononuclear cell migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of mononuclear cell migration) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the rate, frequency or extent of mononuclear cell migration. Mononuclear cell migration is the movement of a mononuclear cell within or between different tissues and organs of the body.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-02-16T02:11:53Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0071675") +AnnotationAssertion(rdfs:label "regulation of mononuclear cell migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of mononuclear cell migration) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that decreases the rate, frequency or extent of mononuclear cell migration. Mononuclear cell migration is the movement of a mononuclear cell within or between different tissues and organs of the body.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-02-16T02:13:55Z") +AnnotationAssertion(Annotation( "GOC:mah") "down regulation of mononuclear cell migration") +AnnotationAssertion(Annotation( "GOC:mah") "down-regulation of mononuclear cell migration") +AnnotationAssertion(Annotation( "GOC:mah") "downregulation of mononuclear cell migration") +AnnotationAssertion(Annotation( "GOC:mah") "inhibition of mononuclear cell migration") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0071676") +AnnotationAssertion(rdfs:label "negative regulation of mononuclear cell migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of mononuclear cell migration) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that increases the rate, frequency or extent of mononuclear cell migration. Mononuclear cell migration is the movement of a mononuclear cell within or between different tissues and organs of the body.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-02-16T02:15:29Z") +AnnotationAssertion(Annotation( "GOC:mah") "up regulation of mononuclear cell migration") +AnnotationAssertion(Annotation( "GOC:mah") "up-regulation of mononuclear cell migration") +AnnotationAssertion(Annotation( "GOC:mah") "upregulation of mononuclear cell migration") +AnnotationAssertion(Annotation( "GOC:mah") "activation of mononuclear cell migration") +AnnotationAssertion(Annotation( "GOC:mah") "stimulation of mononuclear cell migration") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0071677") +AnnotationAssertion(rdfs:label "positive regulation of mononuclear cell migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (organism emergence from protective structure) AnnotationAssertion(Annotation( "GOC:mah") "The developmental process in which an organism emerges from a surrounding protective structure such as an egg or pupa case.") @@ -40382,6 +105651,91 @@ AnnotationAssertion( "organism emergence from protective structure") SubClassOf( ) +# Class: (protein localization to extracellular region) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process in which a protein is transported from one specific location in the extracellular region to another, or maintained in a specific extracellular location.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-02-25T04:00:13Z") +AnnotationAssertion(Annotation( "GOC:mah") "protein localisation in extracellular region") +AnnotationAssertion( "protein localization in extracellular region") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0071692") +AnnotationAssertion(rdfs:label "protein localization to extracellular region") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (anatomical structure maturation) + +AnnotationAssertion(Annotation( "GOC:mah") "A developmental process, independent of morphogenetic (shape) change, that is required for an anatomical structure to attain its fully functional state.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-03-02T11:43:38Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0071695") +AnnotationAssertion(rdfs:label "anatomical structure maturation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (ectodermal placode development) + +AnnotationAssertion(Annotation( "GOC:mah") "The progression of an ectodermal placode over time from its initial formation until its mature state. An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-03-02T11:48:01Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0071696") +AnnotationAssertion(rdfs:label "ectodermal placode development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (ectodermal placode morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mah") "The process in which the anatomical structures of an ectodermal placode are generated and organized. An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-03-02T11:49:51Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0071697") +AnnotationAssertion(rdfs:label "ectodermal placode morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (olfactory placode development) + +AnnotationAssertion(Annotation( "GOC:mah") "The progression of the olfactory placode over time from its initial formation until its mature state. The olfactory placode is a thickening of the neural ectoderm in the head region of the vertebrate embryo which develops into the olfactory region of the nasal cavity.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-03-02T12:45:14Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0071698") +AnnotationAssertion(rdfs:label "olfactory placode development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (olfactory placode morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mah") "The process in which the anatomical structures of the olfactory placode are generated and organized. The olfactory placode is a thickening of the neural ectoderm in the head region of the vertebrate embryo which develops into the olfactory region of the nasal cavity.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-03-02T12:45:45Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0071699") +AnnotationAssertion(rdfs:label "olfactory placode morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (olfactory placode maturation) + +AnnotationAssertion(Annotation( "GOC:mah") "A developmental process, independent of morphogenetic (shape) change, that is required for the olfactory placode to attain its fully functional state. The olfactory placode is a thickening of the neural ectoderm in the head region of the vertebrate embryo which develops into the olfactory region of the nasal cavity.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-03-02T01:10:54Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0071700") +AnnotationAssertion(rdfs:label "olfactory placode maturation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (organic substance transport) AnnotationAssertion(Annotation( "GOC:mah") "The directed movement of organic substances into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore. An organic substance is a molecular entity that contains carbon.") @@ -40390,6 +105744,7 @@ AnnotationAssertion( AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0071702") AnnotationAssertion(rdfs:label "organic substance transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (organic substance metabolic process) @@ -40402,6 +105757,7 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0071704") AnnotationAssertion(rdfs:label "organic substance metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) # Class: (nitrogen compound transport) @@ -40412,8 +105768,215 @@ AnnotationAssertion( AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0071705") AnnotationAssertion(rdfs:label "nitrogen compound transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (immunoglobulin heavy chain V-D-J recombination) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") "The process in which immunoglobulin heavy chain V, D, and J gene segments are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS).") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-03-09T04:20:31Z") +AnnotationAssertion(Annotation( "GOC:add") "immunoglobulin V(D)J joining") +AnnotationAssertion(Annotation( "GOC:add") "immunoglobulin V(D)J recombination") +AnnotationAssertion(Annotation( "GOC:add") "immunoglobulin V-D-J joining") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0071707") +AnnotationAssertion(rdfs:label "immunoglobulin heavy chain V-D-J recombination") +SubClassOf( ) + +# Class: (immunoglobulin light chain V-J recombination) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781735149") "The process in which immunoglobulin light chain V and J gene segments are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS).") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-03-09T04:22:29Z") +AnnotationAssertion(Annotation( "GOC:add") "immunoglobulin V(D)J joining") +AnnotationAssertion(Annotation( "GOC:add") "immunoglobulin V(D)J recombination") +AnnotationAssertion(Annotation( "GOC:add") "immunoglobulin V-J joining") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0071708") +AnnotationAssertion(rdfs:label "immunoglobulin light chain V-J recombination") +SubClassOf( ) + +# Class: (membrane assembly) + +AnnotationAssertion(Annotation( "GOC:mah") "The aggregation, arrangement and bonding together of a set of components to form a membrane.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-03-10T11:19:17Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0071709") +AnnotationAssertion(rdfs:label "membrane assembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (basement membrane organization) + +AnnotationAssertion(Annotation( "GOC:mah") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the basement membrane.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-03-10T11:57:10Z") +AnnotationAssertion(Annotation( "GOC:mah") "basement membrane organisation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0071711") +AnnotationAssertion(rdfs:comment "Note that this term has no relationship to 'membrane organization ; GO:0061024' because the basement membrane is not a lipid bilayer.") +AnnotationAssertion(rdfs:label "basement membrane organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (beak development) + +AnnotationAssertion(Annotation( "GOC:lp") Annotation( "ISBN:0702008729") "The progression of the beak over time from its initial formation until its mature state. The avian beak is an external anatomical structure, in the head region, that is adapted for feeding self and young, catching prey, probing, etc. It encompasses, but is not restricted to, the maxilla, mandible, maxillary rhamphotheca, mandibular rhamphotheca, nostril, nasal fossa, nasal bones, egg tooth and rictus.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-03-17T03:52:48Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0071728") +AnnotationAssertion(rdfs:label "beak development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (beak morphogenesis) + +AnnotationAssertion(Annotation( "GOC:lp") Annotation( "ISBN:0702008729") "The process in which the anatomical structures of the beak are generated and organized. The avian beak is an external anatomical structure, in the head region, that is adapted for feeding self and young, catching prey, probing, etc. It encompasses, but is not restricted to, the maxilla, mandible, maxillary rhamphotheca, mandibular rhamphotheca, nostril, nasal fossa, nasal bones, egg tooth and rictus.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-03-17T03:54:34Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0071729") +AnnotationAssertion(rdfs:label "beak morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (beak formation) + +AnnotationAssertion(Annotation( "GOC:lp") Annotation( "ISBN:0702008729") "The process that gives rise to the beak. This process pertains to the initial formation of a structure from unspecified parts. The avian beak is an external anatomical structure, in the head region, that is adapted for feeding self and young, catching prey, probing, etc. It encompasses, but is not restricted to, the maxilla, mandible, maxillary rhamphotheca, mandibular rhamphotheca, nostril, nasal fossa, nasal bones, egg tooth and rictus.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-03-17T03:57:07Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0071730") +AnnotationAssertion(rdfs:label "beak formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (IgG immunoglobulin complex) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781765196") "A protein complex composed of two identical immunoglobulin heavy chains of an IgG isotype and two identical immunoglobulin light chains, held together by disulfide bonds. An IgG immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-03-24T01:44:53Z") +AnnotationAssertion(Annotation( "GOC:add") "IgG1") +AnnotationAssertion(Annotation( "GOC:add") "IgG2") +AnnotationAssertion(Annotation( "GOC:add") "IgG2a") +AnnotationAssertion(Annotation( "GOC:add") "IgG2b") +AnnotationAssertion(Annotation( "GOC:add") "IgG2c") +AnnotationAssertion(Annotation( "GOC:add") "IgG3") +AnnotationAssertion(Annotation( "GOC:add") "IgG4") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0071735") +AnnotationAssertion(rdfs:comment "Note that an IgG immunoglobulin complex has the function of antigen binding if a suitable antigen is available. Also, IgG isotypes vary by species.") +AnnotationAssertion(rdfs:label "IgG immunoglobulin complex") +SubClassOf( ) + +# Class: (IgD immunoglobulin complex) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781765196") Annotation( "PMID:11282392") "A protein complex composed of two identical immunoglobulin heavy chains of the IgD isotype and two identical immunoglobulin light chains, held together by disulfide bonds. An IgD immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-03-24T01:44:53Z") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0071738") +AnnotationAssertion(rdfs:comment "Note that an IgD immunoglobulin complex has the function of antigen binding if a suitable antigen is available.") +AnnotationAssertion(rdfs:label "IgD immunoglobulin complex") +SubClassOf( ) + +# Class: (IgE immunoglobulin complex) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781765196") "A protein complex composed of two identical immunoglobulin heavy chains of the IgE isotype and two identical immunoglobulin light chains, held together by disulfide bonds. An IgE immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-03-24T01:44:53Z") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0071742") +AnnotationAssertion(rdfs:comment "Note that an IgE immunoglobulin complex has the function of antigen binding if a suitable antigen is available.") +AnnotationAssertion(rdfs:label "IgE immunoglobulin complex") +SubClassOf( ) + +# Class: (IgA immunoglobulin complex) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781765196") Annotation( "PMID:16362985") "A protein complex composed of two identical immunoglobulin heavy chains of the IgA isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and sometimes complexed with J chain or J chain and secretory component. An IgA immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-03-24T01:44:53Z") +AnnotationAssertion(Annotation( "GOC:add") "IgA1 antibody") +AnnotationAssertion(Annotation( "GOC:add") "IgA2 antibody") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0071745") +AnnotationAssertion(rdfs:comment "Note that an IgA immunoglobulin complex has the function of antigen binding if a suitable antigen is available.") +AnnotationAssertion(rdfs:label "IgA immunoglobulin complex") +SubClassOf( ) + +# Class: (IgM immunoglobulin complex) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "ISBN:0781765196") Annotation( "PMID:20176268") "A protein complex composed of two identical immunoglobulin heavy chains of the IgM isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and in its circulating form complexed with J chain in polymeric forms. An IgM immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-03-24T01:44:53Z") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0071753") +AnnotationAssertion(rdfs:comment "Note that an IgM immunoglobulin complex has the function of antigen binding if a suitable antigen is available.") +AnnotationAssertion(rdfs:label "IgM immunoglobulin complex") +SubClassOf( ) + +# Class: (nuclear membrane organization) + +AnnotationAssertion(Annotation( "GOC:mah") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear inner or outer membrane.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-03-29T03:59:35Z") +AnnotationAssertion(Annotation( "GOC:mah") "nuclear membrane organisation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:mah") "nuclear membrane organization and biogenesis") +AnnotationAssertion( "GO:0071763") +AnnotationAssertion(rdfs:label "nuclear membrane organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (nuclear outer membrane organization) + +AnnotationAssertion(Annotation( "GOC:mah") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear outer membrane.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-03-29T04:03:37Z") +AnnotationAssertion(Annotation( "GOC:mah") "nuclear outer membrane organisation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:mah") "nuclear outer membrane organization and biogenesis") +AnnotationAssertion( "GO:0071764") +AnnotationAssertion(rdfs:label "nuclear outer membrane organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (protein transmembrane transport) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:vw") "The process in which a protein is transported across a membrane.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-09-03T02:54:26Z") +AnnotationAssertion( "protein membrane transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0071806") +AnnotationAssertion(rdfs:comment "Note that this term is not intended for use in annotating lateral movement within membranes.") +AnnotationAssertion(rdfs:label "protein transmembrane transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (protein-DNA complex organization) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein-DNA complex.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-09-08T10:03:26Z") +AnnotationAssertion(Annotation( "GOC:mah") "DNA-protein complex subunit organization") +AnnotationAssertion(Annotation( "GOC:mah") "protein-DNA complex subunit organisation") +AnnotationAssertion( "protein-DNA complex subunit organization") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0071824") +AnnotationAssertion(rdfs:label "protein-DNA complex organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (protein-RNA complex organization) AnnotationAssertion(Annotation( "GOC:mah") "Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a ribonucleoprotein complex.") @@ -40427,6 +105990,7 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0071826") AnnotationAssertion(rdfs:label "protein-RNA complex organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (mating pheromone secretion) @@ -40455,6 +106019,165 @@ AnnotationAssertion( "cellular component organization or biogenesis") SubClassOf( ) +# Class: (response to monoamine) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monoamine stimulus. A monoamine is any of a group of molecular messengers that contain one amino group that is connected to an aromatic ring by ethylene group (-CH2-CH2-). Monoamines are derived from the aromatic amino acids phenylalanine, tyrosine, histidine and tryptophan.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-09-13T02:36:37Z") +AnnotationAssertion(Annotation( "GOC:dos") "response to monoamine stimulus") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0071867") +AnnotationAssertion(rdfs:label "response to monoamine") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (cellular response to monoamine stimulus) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monoamine stimulus. A monoamine is any of a group of molecular messengers that contain one amino group that is connected to an aromatic ring by ethylene group (-CH2-CH2-). Monoamines are derived from the aromatic amino acids phenylalanine, tyrosine, histidine and tryptophan.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-09-13T02:38:52Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0071868") +AnnotationAssertion(rdfs:label "cellular response to monoamine stimulus") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (response to catecholamine) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a catecholamine stimulus. A catecholamine is any of a group of biogenic amines that includes 4-(2-aminoethyl)pyrocatechol [4-(2-aminoethyl)benzene-1,2-diol] and derivatives formed by substitution.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-09-13T02:51:13Z") +AnnotationAssertion(Annotation( "GOC:dos") "response to catecholamine stimulus") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0071869") +AnnotationAssertion(rdfs:label "response to catecholamine") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (cellular response to catecholamine stimulus) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a catecholamine stimulus. A catecholamine is any of a group of biogenic amines that includes 4-(2-aminoethyl)pyrocatechol [4-(2-aminoethyl)benzene-1,2-diol] and derivatives formed by substitution.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-09-13T02:54:50Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0071870") +AnnotationAssertion(rdfs:label "cellular response to catecholamine stimulus") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (response to epinephrine) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epinephrine stimulus. Epinephrine is a catecholamine that has the formula C9H13NO3; it is secreted by the adrenal medulla to act as a hormone, and released by certain neurons to act as a neurotransmitter active in the central nervous system.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-09-13T03:27:48Z") +AnnotationAssertion(Annotation( "GOC:mah") "response to adrenaline stimulus") +AnnotationAssertion(Annotation( "GOC:dos") "response to epinephrine stimulus") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0071871") +AnnotationAssertion(rdfs:comment "Note that epinephrine and norepinephrine are ligands for the same receptors, and there are multiple adrenergic receptors.") +AnnotationAssertion(rdfs:label "response to epinephrine") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (cellular response to epinephrine stimulus) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epinephrine stimulus. Epinephrine is a catecholamine that has the formula C9H13NO3; it is secreted by the adrenal medulla to act as a hormone, and released by certain neurons to act as a neurotransmitter active in the central nervous system.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-09-13T03:31:40Z") +AnnotationAssertion(Annotation( "GOC:mah") "cellular response to adrenaline stimulus") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0071872") +AnnotationAssertion(rdfs:comment "Note that epinephrine and norepinephrine are ligands for the same receptors, and there are multiple adrenergic receptors.") +AnnotationAssertion(rdfs:label "cellular response to epinephrine stimulus") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (response to norepinephrine) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a norepinephrine stimulus. Norepinephrine is a catecholamine that has the formula C8H11NO3; it acts as a hormone, and as a neurotransmitter in most of the sympathetic nervous system.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-09-13T03:31:53Z") +AnnotationAssertion(Annotation( "GOC:mah") "response to noradrenaline stimulus") +AnnotationAssertion(Annotation( "GOC:dos") "response to norepinephrine stimulus") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0071873") +AnnotationAssertion(rdfs:comment "Note that epinephrine and norepinephrine are ligands for the same receptors, and there are multiple adrenergic receptors.") +AnnotationAssertion(rdfs:label "response to norepinephrine") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (cellular response to norepinephrine stimulus) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mah") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a norepinephrine stimulus. Norepinephrine is a catecholamine that has the formula C8H11NO3; it acts as a hormone, and as a neurotransmitter in most of the sympathetic nervous system.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-09-13T03:33:32Z") +AnnotationAssertion(Annotation( "GOC:mah") "cellular response to noradrenaline stimulus") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0071874") +AnnotationAssertion(rdfs:comment "Note that epinephrine and norepinephrine are ligands for the same receptors, and there are multiple adrenergic receptors.") +AnnotationAssertion(rdfs:label "cellular response to norepinephrine stimulus") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (leukocyte apoptotic process) + +AnnotationAssertion(Annotation( "CL:0000738") Annotation( "GOC:BHF") Annotation( "GOC:mah") Annotation( "GOC:mtg_apoptosis") "Any apoptotic process in a leukocyte, an achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-09-14T12:44:09Z") +AnnotationAssertion( "leukocyte apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0071887") +AnnotationAssertion(rdfs:comment "Note that a lymphocyte is a cell of the B cell, T cell, or natural killer cell lineage (CL:0000542).") +AnnotationAssertion(rdfs:label "leukocyte apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectAllValuesFrom( )) + +# Class: (macrophage apoptotic process) + +AnnotationAssertion(Annotation( "CL:0000235") Annotation( "GOC:BHF") Annotation( "GOC:mah") Annotation( "GOC:mtg_apoptosis") "Any apoptotic process in a macrophage, a mononuclear phagocyte present in a variety of tissues.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-09-14T12:50:40Z") +AnnotationAssertion( "macrophage apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:yaf") "AICD") +AnnotationAssertion(Annotation( "GOC:yaf") "activation-induced cell death") +AnnotationAssertion( "GO:0071888") +AnnotationAssertion(rdfs:comment "Note that a lymphocyte is a cell of the B cell, T cell, or natural killer cell lineage (CL:0000542).") +AnnotationAssertion(rdfs:label "macrophage apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (bicarbonate binding) + +AnnotationAssertion(Annotation( "GOC:curators") "Binding to bicarbonate ions (CHO3-).") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-09-14T01:47:43Z") +AnnotationAssertion( "CHO3- ion binding binding") +AnnotationAssertion(Annotation( "CHEBI:17544") "hydrogencarbonate binding") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0071890") +AnnotationAssertion(rdfs:label "bicarbonate binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (odontoblast differentiation) + +AnnotationAssertion(Annotation( "GOC:sl") Annotation( "PMID:20425127") "The process in which a relatively unspecialized cell of neural crest origin acquires the specialized features of an odontoblast, a cell on the outer surface of the dental pulp whose biological function is the creation of dentin.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-09-14T04:00:40Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0071895") +AnnotationAssertion(rdfs:label "odontoblast differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (DNA biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:mah") "The biosynthetic process resulting in the formation of DNA.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-09-15T02:14:33Z") +AnnotationAssertion(Annotation( "GOC:mah") "DNA anabolism") +AnnotationAssertion(Annotation( "GOC:mah") "DNA biosynthesis") +AnnotationAssertion(Annotation( "GOC:mah") "DNA formation") +AnnotationAssertion(Annotation( "GOC:mah") "DNA synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0071897") +AnnotationAssertion(rdfs:label "DNA biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (cell periphery) AnnotationAssertion(Annotation( "GOC:pdt") "The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures.") @@ -40479,6 +106202,1436 @@ AnnotationAssertion(rdfs:label "elas SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (extracellular exosome assembly) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:tfm") Annotation( "PMID:19442504") Annotation( "PMID:27462458") "The aggregation, arrangement and bonding together of a set of components to form an extracellular vesicular exosome, a membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Exosomes are defined by their size, which generally ranges from 30 nm to 100 nm.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-10-18T03:44:18Z") +AnnotationAssertion(Annotation( "GOC:vesicles") "extracellular vesicular exosome assembly") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0071971") +AnnotationAssertion(rdfs:label "extracellular exosome assembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (renal system development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") Annotation( "GOC:yaf") Annotation( "http://en.wikibooks.org/wiki/Human_Physiology/The_Urinary_System") "The process whose specific outcome is the progression of the renal system over time, from its formation to the mature structure. The renal system maintains fluid balance and contributes to electrolyte balance, acid/base balance, and disposal of nitrogenous waste products. In humans, the renal system comprises a pair of kidneys, a pair of ureters, urinary bladder, urethra, sphincter muscle and associated blood vessels.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-01-25T10:31:00Z") +AnnotationAssertion(Annotation( "GOC:yaf") "urinary system development") +AnnotationAssertion(Annotation( "GOC:yaf") Annotation( "PMID:17881463") "urinary tract development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072001") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "renal system development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (Malpighian tubule development) + +AnnotationAssertion(Annotation( "FBbt:00005786") Annotation( "GOC:mtg_kidney_jan10") Annotation( "PMID:19783135") "The process whose specific outcome is the progression of the Malpighian tubule over time, from its formation to the mature structure. A Malpighian tubule is a fine, thin-walled excretory tubule in insects which leads into the posterior part of the gut.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-01-25T10:54:30Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072002") +AnnotationAssertion(rdfs:label "Malpighian tubule development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectAllValuesFrom( )) + +# Class: (kidney rudiment formation) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The developmental process pertaining to the initial formation of a kidney rudiment from unspecified parts. A kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-01-25T11:18:58Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "kidney anlage formation") +AnnotationAssertion( "GO:0072003") +AnnotationAssertion(rdfs:label "kidney rudiment formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (nephron development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the nephron over time, from its formation to the mature structure. A nephron is the functional unit of the kidney.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-01-25T01:37:16Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:rph") "nephrogenesis") +AnnotationAssertion( "GO:0072006") +AnnotationAssertion(rdfs:label "nephron development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (mesangial cell differentiation) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesangial cells of the kidney as it progresses from its formation to the mature state.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-01-25T01:59:09Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072007") +AnnotationAssertion(rdfs:label "mesangial cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (nephron epithelium development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the nephron epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The nephron epithelium is a tissue that covers the surface of a nephron.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-01-25T02:01:39Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072009") +AnnotationAssertion(rdfs:label "nephron epithelium development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (glomerular epithelium development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the glomerular epithelium over time, from its formation to the mature structure. The glomerular epithelium is an epithelial tissue that covers the outer surfaces of the glomerulus. The glomerular epithelium consists of both parietal and visceral epithelium. Metanephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the metanephros.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-01-25T02:02:14Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072010") +AnnotationAssertion(rdfs:label "glomerular epithelium development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (glomerular endothelium development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the glomerular endothelium over time, from its formation to the mature structure. The glomerular endothelium is an epithelial tissue that covers the internal surfaces of the glomerulus.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-01-25T02:02:57Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072011") +AnnotationAssertion(rdfs:label "glomerular endothelium development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (glomerulus vasculature development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The biological process whose specific outcome is the progression of a glomerulus vasculature from an initial condition to its mature state. This process begins with the formation of the glomerulus vasculature and ends with the mature structure. The glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the glomerulus.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-01-25T02:05:04Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "glomerulus capillary development") +AnnotationAssertion( "GO:0072012") +AnnotationAssertion(rdfs:label "glomerulus vasculature development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (proximal tubule development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the proximal tubule over time, from its formation to the mature structure. In mammals, the proximal tubule is a nephron tubule that connects Bowman's capsule to the descending thin limb of the loop of Henle. It has a brush border epithelial morphology.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-01-25T02:33:46Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072014") +AnnotationAssertion(rdfs:label "proximal tubule development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (podocyte development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of a glomerular visceral epithelial cell over time, from its formation to the mature structure. A glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/23000"^^xsd:anyURI) +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-01-25T02:12:45Z") +AnnotationAssertion( "glomerular visceral epithelial cell development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072015") +AnnotationAssertion(rdfs:label "podocyte development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (glomerular parietal epithelial cell development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of a glomerular parietal epithelial cell over time, from its formation to the mature structure. Glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-01-25T02:13:16Z") +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "Bowman's capsule development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072016") +AnnotationAssertion(rdfs:label "glomerular parietal epithelial cell development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (distal tubule development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the distal tubule over time, from its formation to the mature structure. In mammals, the distal tubule is a nephron tubule that begins at the macula densa and extends to the connecting tubule.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-01-25T02:34:19Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072017") +AnnotationAssertion(rdfs:label "distal tubule development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (proximal convoluted tubule development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the proximal convoluted tubule over time, from its formation to the mature structure. The proximal convoluted tubule is the most proximal portion of the proximal tubule and extends from the glomerular capsule to the proximal straight tubule.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-01-25T02:35:35Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072019") +AnnotationAssertion(rdfs:label "proximal convoluted tubule development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (proximal straight tubule development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the proximal straight tubule over time, from its formation to the mature structure. The proximal straight tubule is the part of the descending limb that extends from the proximal convoluted tubule to the descending thin tubule.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-01-25T02:36:14Z") +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "S3 development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072020") +AnnotationAssertion(rdfs:label "proximal straight tubule development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (ascending thin limb development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of an ascending thin limb over time, from its formation to the mature structure. The ascending thin limb is a segment of a nephron tubule lying in the inner medulla that is permeable to ions but not to water and has a simple epithelium; active transepithelial solute transport is absent.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-01-25T02:37:13Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072021") +AnnotationAssertion(rdfs:label "ascending thin limb development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (descending thin limb development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the descending thin limb over time, from its formation to the mature structure. The descending thin limb is a part of the loop of Henle situated just after the proximal straight tubule (S3). It extends to the tip of the loop of Henle.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-01-25T02:37:47Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072022") +AnnotationAssertion(rdfs:label "descending thin limb development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (thick ascending limb development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the thick ascending limb over time, from its formation to the mature structure. The thick ascending limb is the last part of the loop of Henle. Its thick, mitochondria-rich epithelium characterizes the outer medulla, and is responsible for very avid active salt transport. At the macula densa, the thick ascending limb connects to the distal convoluted tubule.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-01-25T02:39:51Z") +AnnotationAssertion( "GO:0072026") +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "TAL development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072023") +AnnotationAssertion(rdfs:label "thick ascending limb development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (macula densa development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the macula densa over time, from its formation to the mature structure. The macula densa is an area of specialized cells in the distal tubule that makes contact with the vascular pole of the glomerulus.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-01-25T02:40:15Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072024") +AnnotationAssertion(rdfs:label "macula densa development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (distal convoluted tubule development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the distal convoluted tubule over time, from its formation to the mature structure. The distal convoluted tubule is the first segment of the nephron lying just downstream from the loop of Henle, immediately after the macula densa. Among other functions, in humans it is responsible for the reabsorption of about 5% of filtered sodium via the thiazide-sensitive Na-Cl symporter.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-01-25T02:40:45Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072025") +AnnotationAssertion(rdfs:label "distal convoluted tubule development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (connecting tubule development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the connecting tubule over time, from its formation to the mature structure. The connecting tubule is a tubular segment of the nephron; it connects the distal convoluted tubule to the collecting duct.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-01-25T02:42:05Z") +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "connecting duct development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072027") +AnnotationAssertion(rdfs:label "connecting tubule development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (nephron morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the anatomical structures of the nephron are generated and organized. A nephron is the functional unit of the kidney.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-01-25T02:45:52Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072028") +AnnotationAssertion(rdfs:label "nephron morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (long nephron development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of a long nephron over time, from its formation to the mature structure. Long nephrons are associated with juxtamedullary glomeruli and extend into the inner medulla.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-01-25T02:49:08Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "juxtamedullary nephron development") +AnnotationAssertion( "GO:0072029") +AnnotationAssertion(rdfs:label "long nephron development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (short nephron development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of a short nephron over time, from its formation to the mature structure. Short nephrons are associated with mid-cortical and superficial glomeruli, are situated entirely in the outer medulla, and have no thin ascending limb.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-01-25T02:49:32Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072030") +AnnotationAssertion(rdfs:label "short nephron development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (proximal convoluted tubule segment 1 development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") Annotation( "MA:0002612") "The process whose specific outcome is the progression of the S1 portion of the proximal convoluted tubule over time, from its formation to the mature structure. The S1 portion is the initial portion of the proximal convoluted tubule and is responsible for avid reabsorption of water and solutes.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-01-25T02:55:57Z") +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "S1 development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072031") +AnnotationAssertion(rdfs:label "proximal convoluted tubule segment 1 development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (proximal convoluted tubule segment 2 development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") Annotation( "MA:0002613") "The process whose specific outcome is the progression of the S2 portion of the proximal convoluted tubule over time, from its formation to the mature structure. The S2 portion of the tubule is involved in reabsorption of water and sodium chloride.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-01-25T02:56:36Z") +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "S2 development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072032") +AnnotationAssertion(rdfs:label "proximal convoluted tubule segment 2 development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (renal vesicle formation) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The developmental process pertaining to the initial formation of the renal vesicle from condensed mesenchymal cells. The renal vesicle is the primordial structure of the nephron epithelium, and is formed by the condensation of mesenchymal cells.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-01-25T02:57:03Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "nephron epithelium formation") +AnnotationAssertion( "GO:0072033") +AnnotationAssertion(rdfs:label "renal vesicle formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (mesenchymal to epithelial transition involved in renal vesicle formation) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the renal vesicle.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-01-25T03:04:24Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072036") +AnnotationAssertion(rdfs:label "mesenchymal to epithelial transition involved in renal vesicle formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (mesenchymal stem cell maintenance involved in nephron morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which an organism retains a population of mesenchymal stem cells that contributes to the shaping of a nephron. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-01-25T03:08:05Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072038") +AnnotationAssertion(rdfs:label "mesenchymal stem cell maintenance involved in nephron morphogenesis") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:mtg_kidney_jan10") "Any process that modulates the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-01-25T03:08:34Z") +AnnotationAssertion( "regulation of mesenchymal stem cell apoptotic process involved in nephron morphogenesis") +AnnotationAssertion( "regulation of mesenchymal stem cell apoptosis involved in nephron morphogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072039") +AnnotationAssertion(rdfs:label "regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:mtg_kidney_jan10") "Any process that reduces the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-01-25T03:09:30Z") +AnnotationAssertion( "negative regulation of mesenchymal stem cell apoptotic process involved in nephron morphogenesis") +AnnotationAssertion( "negative regulation of mesenchymal stem cell apoptosis involved in nephron morphogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072040") +AnnotationAssertion(rdfs:label "negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (positive regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:mtg_kidney_jan10") "Any process that increases the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-01-25T03:10:32Z") +AnnotationAssertion( "positive regulation of mesenchymal stem cell apoptotic process involved in nephron morphogenesis") +AnnotationAssertion( "positive regulation of mesenchymal stem cell apoptosis involved in nephron morphogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072041") +AnnotationAssertion(rdfs:label "positive regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (collecting duct development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of a collecting duct over time, from its formation to the mature structure. The collecting duct responds to vasopressin and aldosterone to regulate water, electrolyte and acid-base balance. It is the final common path through which urine flows before entering the ureter and then emptying into the bladder.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-01-25T03:18:06Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072044") +AnnotationAssertion(rdfs:label "collecting duct development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (renal system pattern specification) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "Any developmental process that results in the creation of defined areas or spaces within an organism to which cells respond and eventually are instructed to differentiate into the anatomical structures of the renal system.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-01-25T03:31:51Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "renal system pattern formation") +AnnotationAssertion( "GO:0072048") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "renal system pattern specification") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (comma-shaped body morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the comma-shaped body is generated and organized. The comma-shaped body is the precursor structure to the S-shaped body that contributes to the morphogenesis of the nephron.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-01-25T03:44:48Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072049") +AnnotationAssertion(rdfs:label "comma-shaped body morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (S-shaped body morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the S-shaped body is generated and organized. The S-shaped body is the successor of the comma-shaped body that contributes to the morphogenesis of the nephron.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-01-25T03:45:19Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072050") +AnnotationAssertion(rdfs:label "S-shaped body morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (juxtaglomerular apparatus development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the juxtaglomerular apparatus over time, from its formation to the mature structure. The juxtaglomerular apparatus is an anatomical structure that lies adjacent to the glomerulus and regulates kidney function.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-01-25T03:52:23Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072051") +AnnotationAssertion(rdfs:label "juxtaglomerular apparatus development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (juxtaglomerulus cell differentiation) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the juxtaglomerulus cells of the kidney as it progresses from its formation to the mature state.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-01-25T03:58:01Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072052") +AnnotationAssertion(rdfs:label "juxtaglomerulus cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (renal inner medulla development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the renal inner medulla over time, from its formation to the mature structure. The renal inner medulla is unique to mammalian kidneys and is the innermost region of the mammalian kidney.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-01-25T03:59:37Z") +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "inner renal medulla development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072053") +AnnotationAssertion(rdfs:label "renal inner medulla development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (renal outer medulla development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the renal outer medulla over time, from its formation to the mature structure. The renal outer medulla is the region of the kidney that lies between the renal cortex and the renal inner medulla.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-01-25T04:00:42Z") +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "outer renal medulla development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072054") +AnnotationAssertion(rdfs:label "renal outer medulla development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (renal cortex development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the renal cortex over time, from its formation to the mature structure. The renal cortex is the outer region of the kidney.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-01-25T04:01:12Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072055") +AnnotationAssertion(rdfs:label "renal cortex development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (pyramid development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the kidney pyramids over time, from its formation to the mature structure. Kidney pyramids are the conical masses that constitute the renal medulla in a multi-lobed mammalian kidney; they contain the loops of Henle and the medullary collecting ducts.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-01-25T04:01:36Z") +AnnotationAssertion(Annotation( "GOC:mah") "kidney pyramid development") +AnnotationAssertion(Annotation( "GOC:mah") "pyramids development") +AnnotationAssertion(Annotation( "GOC:mah") "renal medulla development") +AnnotationAssertion(Annotation( "GOC:mah") "renal pyramid development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072056") +AnnotationAssertion(rdfs:label "pyramid development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (inner stripe development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the inner stripe over time, from its formation to the mature structure. The inner stripe is a deep, centrally located portion of the renal outer medulla and is traversed by thin descending and thick ascending portions of the loops of Henle.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-01-25T04:01:58Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072057") +AnnotationAssertion(rdfs:label "inner stripe development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (outer stripe development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the outer stripe over time, from its formation to the mature structure. The outer stripe is the region of the kidney outer medulla that lies just below the cortex. The proximal straight tubules (S3) characterize this region.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-01-25T04:02:56Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072058") +AnnotationAssertion(rdfs:label "outer stripe development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cortical collecting duct development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the cortical collecting duct over time, from its formation to the mature structure. The cortical collecting duct is the portion of the collecting duct that resides in the renal cortex.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-01-25T04:07:07Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072059") +AnnotationAssertion(rdfs:label "cortical collecting duct development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (outer medullary collecting duct development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the outer medullary collecting duct over time, from its formation to the mature structure. The outer medullary collecting duct is the portion of the collecting duct that lies in the renal outer medulla.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-01-25T04:08:18Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072060") +AnnotationAssertion(rdfs:label "outer medullary collecting duct development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (inner medullary collecting duct development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the inner medullary collecting duct over time, from its formation to the mature structure. The inner medullary collecting duct is the portion of the collecting duct that lies in the renal inner medulla.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-01-25T04:08:45Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072061") +AnnotationAssertion(rdfs:label "inner medullary collecting duct development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (short descending thin limb development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the short descending thin limb over time, from its formation to the mature structure. The short descending thin limb is the descending thin limb of a short nephron that has a squamous epithelial morphology.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-01-25T04:12:39Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072063") +AnnotationAssertion(rdfs:label "short descending thin limb development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (long descending thin limb development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the long descending thin limb over time, from its formation to the mature structure. The long descending thin limb is the descending thin limb of a long nephron that has a squamous epithelial morphology. The long descending limb starts in the inner stripe of the outer medulla and extends into the inner medulla.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-01-25T04:13:17Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072064") +AnnotationAssertion(rdfs:label "long descending thin limb development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (long descending thin limb bend development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the long descending thin limb bend over time, from its formation to the mature structure. The long descending thin limb bend is a part of the descending thin limb of a long nephron that lies beyond the prebend segment.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-01-25T04:13:38Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072065") +AnnotationAssertion(rdfs:label "long descending thin limb bend development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (prebend segment development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the prebend segment over time, from its formation to the mature structure. The prebend segment is a part of the descending thin limb that lies before the bend and exhibits permeabilities characteristic of the ascending limb, especially negligible water permeability.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-01-25T04:14:02Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072066") +AnnotationAssertion(rdfs:label "prebend segment development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (early distal convoluted tubule development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the early distal convoluted tubule over time, from its formation to the mature structure. The early distal convoluted tubule contains DCT cells and is vasopressin-insensitive.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-01-25T04:15:17Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072067") +AnnotationAssertion(rdfs:label "early distal convoluted tubule development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (late distal convoluted tubule development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the late distal convoluted tubule over time, from its formation to the mature structure. The late distal convoluted tubule contains DCT cells and intercalated (IC) alpha and beta cells and is vasopressin-sensitive.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-01-25T04:15:50Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072068") +AnnotationAssertion(rdfs:label "late distal convoluted tubule development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (loop of Henle development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the loop of Henle over time, from its formation to the mature structure. The loop of Henle is a nephron tubule that connects the proximal convoluted tubule to the distal convoluted tubule.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-01-25T04:20:27Z") +AnnotationAssertion( "GO:0072018") +AnnotationAssertion( "intermediate tubule development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072070") +AnnotationAssertion(rdfs:label "loop of Henle development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (kidney interstitial fibroblast differentiation) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the interstitial fibroblast of the kidney as it progresses from its formation to the mature state.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-01-25T04:34:31Z") +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "kidney interstitial cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072071") +AnnotationAssertion(rdfs:label "kidney interstitial fibroblast differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (kidney epithelium development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of an epithelium in the kidney over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-01-25T04:37:42Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072073") +AnnotationAssertion(rdfs:label "kidney epithelium development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (kidney mesenchyme development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The biological process whose specific outcome is the progression of a kidney mesenchyme from an initial condition to its mature state. This process begins with the formation of kidney mesenchyme and ends with the mature structure. Kidney mesenchyme is the tissue made up of loosely connected mesenchymal cells in the kidney.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-01-25T04:39:04Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072074") +AnnotationAssertion(rdfs:label "kidney mesenchyme development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (metanephric mesenchyme development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The biological process whose specific outcome is the progression of a metanephric mesenchyme from an initial condition to its mature state. This process begins with the formation of metanephric mesenchyme and ends with the mature structure. Metanephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the metanephros.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-01-25T04:40:11Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072075") +AnnotationAssertion(rdfs:label "metanephric mesenchyme development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (nephrogenic mesenchyme development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The biological process whose specific outcome is the progression of a nephrogenic mesenchyme from an initial condition to its mature state. This process begins with the formation of nephrogenic mesenchyme and ends with the mature structure. Nephrogenic mesenchyme is the tissue made up of loosely connected mesenchymal cells in the nephron.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-01-25T04:40:44Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072076") +AnnotationAssertion(rdfs:label "nephrogenic mesenchyme development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (renal vesicle morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the anatomical structures of the renal vesicle are generated and organized. The renal vesicle is the primordial structure of the nephron epithelium, and is formed by the condensation of mesenchymal cells.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-02-01T02:21:06Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072077") +AnnotationAssertion(rdfs:label "renal vesicle morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (nephron tubule morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the anatomical structures of a nephron tubule are generated and organized. A nephron tubule is an epithelial tube that is part of the nephron, the functional part of the kidney.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-02-01T02:25:14Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072078") +AnnotationAssertion(rdfs:label "nephron tubule morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (nephron tubule formation) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The developmental process pertaining to the initial formation of a nephron tubule from unspecified parts. A nephron tubule is an epithelial tube that is part of the nephron, the functional part of the kidney.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-02-01T02:29:26Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072079") +AnnotationAssertion(rdfs:label "nephron tubule formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (nephron tubule development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The progression of a nephron tubule over time, from its initial formation to the mature structure. A nephron tubule is an epithelial tube that is part of the nephron, the functional part of the kidney.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-02-01T02:32:12Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072080") +AnnotationAssertion(rdfs:label "nephron tubule development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (renal vesicle development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the renal vesicle over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The renal vesicle is the primordial structure of the nephron epithelium, and is formed by the condensation of mesenchymal cells.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-02-08T01:18:31Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072087") +AnnotationAssertion(rdfs:label "renal vesicle development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (nephron epithelium morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the anatomical structures of the nephron epithelium are generated and organized. The nephron epithelium is a tissue that covers the surface of a nephron.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-02-08T01:19:06Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072088") +AnnotationAssertion(rdfs:label "nephron epithelium morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (stem cell proliferation) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The multiplication or reproduction of stem cells, resulting in the expansion of a stem cell population. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-02-08T02:03:36Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072089") +AnnotationAssertion(rdfs:label "stem cell proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (regulation of stem cell proliferation) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "Any process that modulates the frequency, rate or extent of stem cell proliferation. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-02-08T02:09:03Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072091") +AnnotationAssertion(rdfs:label "regulation of stem cell proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (metanephric renal vesicle formation) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The developmental process pertaining to the initial formation of the metanephros.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-02-10T01:17:11Z") +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "metanephros formation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072093") +AnnotationAssertion(rdfs:label "metanephric renal vesicle formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (anterior/posterior pattern specification involved in kidney development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The developmental process that results in the creation of defined areas or spaces within the kidney along the anterior/posterior axis to which cells respond and eventually are instructed to differentiate.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-02-10T02:06:24Z") +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "kidney anterior/posterior pattern specification") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "anterior/posterior pattern formation involved in kidney development") +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "kidney anterior/posterior pattern formation") +AnnotationAssertion( "GO:0072098") +AnnotationAssertion(rdfs:label "anterior/posterior pattern specification involved in kidney development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (anterior/posterior pattern specification involved in ureteric bud development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The developmental process that results in the creation of defined areas or spaces within the ureteric bud along the anterior/posterior axis to which cells respond and eventually are instructed to differentiate.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-02-10T02:12:09Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "ureteric bud anterior/posterior pattern formation") +AnnotationAssertion( "GO:0072099") +AnnotationAssertion(rdfs:label "anterior/posterior pattern specification involved in ureteric bud development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (glomerulus morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the anatomical structures of the glomerulus are generated and organized. The glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-02-10T02:32:09Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072102") +AnnotationAssertion(rdfs:label "glomerulus morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (glomerulus vasculature morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the anatomical structures of the glomerulus vasculature are generated and organized. The glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the glomerulus.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-02-10T02:34:54Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072103") +AnnotationAssertion(rdfs:label "glomerulus vasculature morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (glomerular capillary formation) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process that gives rise to a glomerular capillary. This process pertains to the initial formation of a structure from unspecified parts.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-02-10T02:40:40Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072104") +AnnotationAssertion(rdfs:label "glomerular capillary formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (ureteric peristalsis) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "A wavelike sequence of involuntary muscular contraction and relaxation that passes along the ureter, impelling the contents onwards. The ureter is one of a pair of thick-walled tubes that transports urine from the kidney pelvis to the urinary bladder.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-02-10T03:07:54Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072105") +AnnotationAssertion(rdfs:label "ureteric peristalsis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of ureteric bud formation) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "Any process that modulates the developmental process pertaining to the initial formation of the ureteric bud from the Wolffian duct.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-02-12T02:34:40Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072106") +AnnotationAssertion(rdfs:label "regulation of ureteric bud formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (positive regulation of ureteric bud formation) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "Any process that increases the rate or extent of the developmental process pertaining to the initial formation of the ureteric bud from the Wolffian duct.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-02-12T02:37:28Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072107") +AnnotationAssertion(rdfs:label "positive regulation of ureteric bud formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "Any process that increases the rate, frequency or extent of the transition where a mesenchymal cell establishes apical/basolateral polarity, forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-02-12T02:45:57Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072108") +AnnotationAssertion(rdfs:label "positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (glomerular mesangium development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the glomerular mesangium over time, from its formation to the mature structure. The glomerular mesangium is the thin membrane connective tissue composed of mesangial cells, which helps to support the capillary loops in a renal glomerulus.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-02-22T10:35:24Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072109") +AnnotationAssertion(rdfs:label "glomerular mesangium development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cell proliferation involved in kidney development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The multiplication or reproduction of cells, resulting in the expansion of the population in the kidney.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-02-22T10:48:45Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072111") +AnnotationAssertion(rdfs:label "cell proliferation involved in kidney development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (podocyte differentiation) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which a relatively unspecialized cell acquires specialized features of a glomerular visceral epithelial cell. A glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/23000"^^xsd:anyURI) +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-02-22T10:52:11Z") +AnnotationAssertion( "glomerular visceral epithelial cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072112") +AnnotationAssertion(rdfs:label "podocyte differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (head kidney development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") Annotation( "ZFA:0000669") "The process whose specific outcome is the progression of the head kidney over time, from its formation to the mature structure. The head kidney is a pronephros that consists of fused bilateral lobes located in the anterior part of the kidney. It is analogous to the mammalian bone marrow and the primary site of definitive hematopoiesis.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-02-22T11:09:38Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072113") +AnnotationAssertion(rdfs:label "head kidney development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (pronephros morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the anatomical structures of the pronephros are generated and organized. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-02-22T11:12:15Z") +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "pronephric kidney morphogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072114") +AnnotationAssertion(rdfs:label "pronephros morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (head kidney morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") Annotation( "ZFA:0000669") "The process in which the anatomical structures of the head kidney are generated and organized. The head kidney is a pronephros that consists of fused bilateral lobes located in the anterior part of the kidney.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-02-22T11:13:37Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072115") +AnnotationAssertion(rdfs:label "head kidney morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (pronephros formation) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The developmental process pertaining to the initial formation of the pronephros. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-02-22T11:16:26Z") +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "pronephric kidney formation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072116") +AnnotationAssertion(rdfs:label "pronephros formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (head kidney formation) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") Annotation( "ZFA:0000669") "The developmental process pertaining to the initial formation of the head kidney. The head kidney is a pronephros that consists of fused bilateral lobes located in the anterior part of the kidney.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-02-22T11:17:20Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072117") +AnnotationAssertion(rdfs:label "head kidney formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (pronephros maturation) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "A developmental process, independent of morphogenetic (shape) change, that is required for the pronephros to attain its fully functional state. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-02-22T11:25:48Z") +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "pronephric kidney maturation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072120") +AnnotationAssertion(rdfs:label "pronephros maturation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (head kidney maturation) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") Annotation( "ZFA:0000669") "A developmental process, independent of morphogenetic (shape) change, that is required for the head kidney to attain its fully functional state. The head kidney is a pronephros that consists of fused bilateral lobes located in the anterior part of the kidney.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-02-22T11:28:08Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072121") +AnnotationAssertion(rdfs:label "head kidney maturation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (renal capsule development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the renal capsule over time, from its formation to the mature structure. The renal capsule is the tough fibrous layer surrounding the kidney, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. During development, it comprises a single layer of flattened cells that lie just above the cortical stroma and the condensed mesenchyme of the nephrogenic zone. It is in this region that the early stages of nephron induction and formation of new generations ureteric bud branches occur, as the kidney expands.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-02-22T02:02:55Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072127") +AnnotationAssertion(rdfs:label "renal capsule development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (renal capsule morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the anatomical structures of the renal capsule are generated and organized. The renal capsule is the tough fibrous layer surrounding the kidney, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. During development, it comprises a single layer of flattened cells that lie just above the cortical stroma and the condensed mesenchyme of the nephrogenic zone. It is in this region that the early stages of nephron induction and formation of new generations ureteric bud branches occur, as the kidney expands.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-02-22T02:06:19Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072128") +AnnotationAssertion(rdfs:label "renal capsule morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (renal capsule formation) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The developmental process pertaining to the initial formation of a renal capsule from unspecified parts. The renal capsule is the tough fibrous layer surrounding the kidney, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. During development, it comprises a single layer of flattened cells that lie just above the cortical stroma and the condensed mesenchyme of the nephrogenic zone. It is in this region that the early stages of nephron induction and formation of new generations ureteric bud branches occur, as the kidney expands.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-02-22T02:08:14Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072129") +AnnotationAssertion(rdfs:label "renal capsule formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (kidney mesenchyme morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the anatomical structures of a kidney mesenchymal tissue are generated and organized. Kidney mesenchyme is the tissue made up of loosely connected mesenchymal cells in the kidney.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-02-22T02:16:43Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072131") +AnnotationAssertion(rdfs:label "kidney mesenchyme morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (mesenchyme morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the anatomical structures of a mesenchymal tissue are generated and organized. A mesenchymal tissue is made up of loosely packed stellate cells.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-02-22T02:17:15Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072132") +AnnotationAssertion(rdfs:label "mesenchyme morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (metanephric mesenchyme morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the anatomical structures of a metanephric mesenchymal tissue are generated and organized. Metanephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the metanephros.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-02-22T02:20:14Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072133") +AnnotationAssertion(rdfs:label "metanephric mesenchyme morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (nephrogenic mesenchyme morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the anatomical structures of a nephrogenic mesenchymal tissue are generated and organized. Nephrogenic mesenchyme is the tissue made up of loosely connected mesenchymal cells in the nephron.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-02-22T02:21:16Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072134") +AnnotationAssertion(rdfs:label "nephrogenic mesenchyme morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (mesenchymal cell proliferation involved in ureteric bud development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population of the ureteric bud, that contributes to ureteric bud development.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-02-22T02:40:38Z") +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "ureteric bud mesenchymal cell proliferation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072138") +AnnotationAssertion(rdfs:label "mesenchymal cell proliferation involved in ureteric bud development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (glomerular parietal epithelial cell differentiation) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which a relatively unspecialized cell acquires specialized features of a glomerular parietal epithelial cell. Glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-02-24T01:33:05Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072139") +AnnotationAssertion(rdfs:label "glomerular parietal epithelial cell differentiation") +SubClassOf( ) + +# Class: (renal interstitial fibroblast development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of a renal interstitial fibroblast over time, from its formation to the mature structure.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-02-24T01:39:05Z") +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "kidney interstitial cell development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072141") +AnnotationAssertion(rdfs:label "renal interstitial fibroblast development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (juxtaglomerulus cell development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of a juxtaglomerulus cell over time, from its formation to the mature structure.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-02-24T01:42:53Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072142") +AnnotationAssertion(rdfs:label "juxtaglomerulus cell development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (mesangial cell development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of a mesangial cell in the kidney over time, from its formation to the mature structure.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-02-24T01:44:28Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072143") +AnnotationAssertion(rdfs:label "mesangial cell development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (epithelial cell migration involved in nephron tubule morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The orderly movement of epithelial cells within a renal tubule that contributes to nephron tubule morphogenesis.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-02-24T02:21:25Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072155") +AnnotationAssertion(rdfs:label "epithelial cell migration involved in nephron tubule morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (distal tubule morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the anatomical structures of a distal tubule are generated and organized. The distal tubule is a nephron tubule that begins at the macula densa and extends to the connecting tubule.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-02-24T02:32:03Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072156") +AnnotationAssertion(rdfs:label "distal tubule morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (epithelial cell migration involved in distal tubule morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The orderly movement of epithelial cells within a renal tubule that contributes to distal tubule morphogenesis.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-02-24T02:33:33Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072157") +AnnotationAssertion(rdfs:label "epithelial cell migration involved in distal tubule morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (proximal tubule morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the anatomical structures of a proximal tubule are generated and organized. The proximal tubule is a nephron tubule that connects Bowman's capsule to the descending thin limb of the loop of Henle. It has a brush border epithelial morphology.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-02-24T02:35:36Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072158") +AnnotationAssertion(rdfs:label "proximal tubule morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (epithelial cell migration involved in proximal tubule morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The orderly movement of epithelial cells within a renal tubule that contributes to proximal tubule morphogenesis.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-02-24T02:37:08Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072159") +AnnotationAssertion(rdfs:label "epithelial cell migration involved in proximal tubule morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (nephron tubule epithelial cell differentiation) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the nephron tubule as it progresses from its formation to the mature state.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-02-24T02:40:11Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072160") +AnnotationAssertion(rdfs:label "nephron tubule epithelial cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (mesenchymal cell differentiation involved in kidney development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of the kidney as it progresses from its formation to the mature state.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-02-26T01:31:49Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072161") +AnnotationAssertion(rdfs:label "mesenchymal cell differentiation involved in kidney development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (mesonephric epithelium development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of an epithelium in the mesonephros over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-02-26T01:40:43Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072163") +AnnotationAssertion(rdfs:label "mesonephric epithelium development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (mesonephric tubule development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The progression of a mesonephric tubule over time, from its initial formation to the mature structure. A mesonephric tubule is an epithelial tube that is part of the mesonephros.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-02-26T01:45:58Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072164") +AnnotationAssertion(rdfs:label "mesonephric tubule development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (anterior mesonephric tubule development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The progression of the anterior mesonephric tubule over time, from its initial formation to the mature structure. The anterior mesonephric tubule is an epithelial tube that is part of the mesonephros.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-02-26T01:47:26Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072165") +AnnotationAssertion(rdfs:label "anterior mesonephric tubule development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (posterior mesonephric tubule development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The progression of the posterior mesonephric tubule over time, from its initial formation to the mature structure. The posterior mesonephric tubule is an epithelial tube that is part of the mesonephros.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-02-26T01:47:50Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072166") +AnnotationAssertion(rdfs:label "posterior mesonephric tubule development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (metanephric tubule development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The progression of a metanephric tubule over time, from its initial formation to the mature structure. A metanephric tubule is an epithelial tube that is part of the metanephros.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-02-26T01:58:18Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072170") +AnnotationAssertion(rdfs:label "metanephric tubule development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (mesonephric tubule morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the anatomical structures of a mesonephric tubule are generated and organized. A mesonephric tubule is an epithelial tube that is part of the mesonephros.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-02-26T02:02:13Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072171") +AnnotationAssertion(rdfs:label "mesonephric tubule morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (mesonephric tubule formation) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The developmental process pertaining to the initial formation of a mesonephric tubule from unspecified parts. A mesonephric tubule is an epithelial tube that is part of the mesonephros.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-02-26T02:02:37Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072172") +AnnotationAssertion(rdfs:label "mesonephric tubule formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (metanephric tubule morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the anatomical structures of a metanephric tubule are generated and organized from an epithelium. A metanephric tubule is an epithelial tube that is part of the metanephros.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-02-26T02:06:42Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072173") +AnnotationAssertion(rdfs:label "metanephric tubule morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (metanephric tubule formation) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The developmental process pertaining to the initial formation of a metanephric tubule.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-02-26T02:07:41Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072174") +AnnotationAssertion(rdfs:label "metanephric tubule formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (epithelial tube formation) AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The developmental process pertaining to the initial formation of an epithelial tube.") @@ -40488,8 +107641,1186 @@ AnnotationAssertion( AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0072175") AnnotationAssertion(rdfs:label "epithelial tube formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (nephric duct development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of a nephric duct over time, from its initial formation to a mature structure. A nephric duct is a tube that drains a primitive kidney.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-02-26T02:27:31Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072176") +AnnotationAssertion(rdfs:label "nephric duct development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (mesonephric duct development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of a mesonephric duct over time, from its initial formation to a mature structure. A mesonephric duct is a tube drains the mesonephros.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-02-26T02:32:22Z") +AnnotationAssertion(Annotation( "GOC:dph") "Wolffian duct development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072177") +AnnotationAssertion(rdfs:label "mesonephric duct development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (nephric duct morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the anatomical structures of the nephric duct are generated and organized. A nephric duct is a tube that drains a primitive kidney.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-02-26T02:35:29Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072178") +AnnotationAssertion(rdfs:label "nephric duct morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (nephric duct formation) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The developmental process pertaining to the initial formation of a nephric duct. A nephric duct is a tube that drains a primitive kidney.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-02-26T02:35:55Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072179") +AnnotationAssertion(rdfs:label "nephric duct formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (mesonephric duct morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the anatomical structures of the mesonephric duct are generated and organized. A mesonephric duct is a tube drains the mesonephros.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-02-26T02:37:13Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") "Wolffian duct morphogenesis") +AnnotationAssertion( "GO:0072180") +AnnotationAssertion(rdfs:label "mesonephric duct morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (mesonephric duct formation) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The developmental process pertaining to the initial formation of a mesonephric duct. A mesonephric duct is a tube that drains the mesonephros.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-02-26T02:38:03Z") +AnnotationAssertion(Annotation( "GOC:dph") "Wolffian duct formation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072181") +AnnotationAssertion(rdfs:label "mesonephric duct formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of nephron tubule epithelial cell differentiation) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "Any process that modulates the frequency, rate or extent of nephron tubule epithelial cell differentiation.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-02-26T02:45:09Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072182") +AnnotationAssertion(rdfs:label "regulation of nephron tubule epithelial cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of nephron tubule epithelial cell differentiation) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "Any process that decreases the frequency, rate or extent of nephron tubule epithelial cell differentiation.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-02-26T02:47:25Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072183") +AnnotationAssertion(rdfs:label "negative regulation of nephron tubule epithelial cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (metanephric cap development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The biological process whose specific outcome is the progression of the metanephric cap from an initial condition to its mature state. The metanephric cap is formed by the condensation of metanephric mesenchymal cells surrounding the ureteric bud tip.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-03-01T01:20:22Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072185") +AnnotationAssertion(rdfs:label "metanephric cap development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (metanephric cap morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the anatomical structures of the metanephric cap are generated and organized. The metanephric cap is formed by the condensation of metanephric mesenchymal cells surrounding the ureteric bud tip.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-03-01T01:22:51Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072186") +AnnotationAssertion(rdfs:label "metanephric cap morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (metanephric cap formation) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The developmental process pertaining to the initial formation of a metanephric cap from unspecified parts. The metanephric cap is formed by the condensation of metanephric mesenchymal cells surrounding the ureteric bud tip.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-03-01T01:26:53Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072187") +AnnotationAssertion(rdfs:label "metanephric cap formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (ureter development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the ureter over time, from its formation to the mature structure. The ureter is a muscular tube that transports urine from the kidney to the urinary bladder or from the Malpighian tubule to the hindgut.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-03-01T01:44:14Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072189") +AnnotationAssertion(rdfs:label "ureter development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (ureter urothelium development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the urothelium of the ureter over time, from its formation to the mature structure. The urothelium is an epithelium that makes up the epithelial tube of the ureter.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-03-01T01:46:31Z") +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "ureter epithelium development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072190") +AnnotationAssertion(rdfs:label "ureter urothelium development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (ureter smooth muscle development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of smooth muscle in the ureter over time, from its formation to the mature structure.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-03-01T01:48:53Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072191") +AnnotationAssertion(rdfs:label "ureter smooth muscle development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (ureter smooth muscle cell differentiation) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell in the ureter.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-03-01T01:55:01Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072193") +AnnotationAssertion(rdfs:label "ureter smooth muscle cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (kidney smooth muscle tissue development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of smooth muscle in the kidney over time, from its formation to the mature structure.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-03-01T02:05:30Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072194") +AnnotationAssertion(rdfs:label "kidney smooth muscle tissue development") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (ureter morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the anatomical structures of the ureter are generated and organized. The ureter is a muscular tube that transports urine from the kidney to the urinary bladder.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-03-01T02:24:55Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072197") +AnnotationAssertion(rdfs:label "ureter morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (mesenchymal cell proliferation involved in ureter development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population of the ureter, that contributes to ureter development.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-03-01T03:24:41Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "ureter mesenchymal cell proliferation") +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "ureteral mesenchymal cell proliferation") +AnnotationAssertion( "GO:0072198") +AnnotationAssertion(rdfs:label "mesenchymal cell proliferation involved in ureter development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of mesenchymal cell proliferation involved in ureter development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "Any process that modulates the frequency, rate or extent of mesenchymal cell proliferation that contributes to the progression of the ureter gland over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-03-01T03:38:13Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "regulation of ureter mesenchymal cell proliferation") +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "regulation of ureteral mesenchymal cell proliferation") +AnnotationAssertion( "GO:0072199") +AnnotationAssertion(rdfs:label "regulation of mesenchymal cell proliferation involved in ureter development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of mesenchymal cell proliferation involved in ureter development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "Any process that decreases the frequency, rate or extent of mesenchymal cell proliferation that contributes to the progression of the ureter gland over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-03-01T03:42:31Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "negative regulation of ureter mesenchymal cell proliferation") +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "negative regulation of ureteral mesenchymal cell proliferation") +AnnotationAssertion( "GO:0072200") +AnnotationAssertion(rdfs:label "negative regulation of mesenchymal cell proliferation involved in ureter development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (negative regulation of mesenchymal cell proliferation) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "Any process that decreases the frequency, rate or extent of mesenchymal cell proliferation. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-03-01T03:43:29Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072201") +AnnotationAssertion(rdfs:label "negative regulation of mesenchymal cell proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (cell differentiation involved in metanephros development) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:mtg_kidney_jan10") "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the metanephros as it progresses from its formation to the mature state.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-03-18T10:40:14Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072202") +AnnotationAssertion(rdfs:label "cell differentiation involved in metanephros development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (cell proliferation involved in metanephros development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The multiplication or reproduction of cells, resulting in the expansion of the population in the metanephros.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-03-18T10:42:27Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072203") +AnnotationAssertion(rdfs:label "cell proliferation involved in metanephros development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (cell-cell signaling involved in metanephros development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "Any process that mediates the transfer of information from one cell to another and contributes to the progression of the metanephros over time, from its formation to the mature organ.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-03-18T10:54:36Z") +AnnotationAssertion(Annotation( "GOC:mah") "cell-cell signalling involved in metanephros development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072204") +AnnotationAssertion(rdfs:label "cell-cell signaling involved in metanephros development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (metanephric collecting duct development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of a collecting duct in the metanephros over time, from its formation to the mature structure. The collecting duct responds to vasopressin and aldosterone to regulate water, electrolyte and acid-base balance. The collecting duct is the final common path through which urine flows before entering the ureter and then emptying into the bladder.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-03-18T11:15:37Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072205") +AnnotationAssertion(rdfs:label "metanephric collecting duct development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (metanephric juxtaglomerular apparatus development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the juxtaglomerular apparatus in the metanephros over time, from its formation to the mature structure. The juxtaglomerular apparatus is an anatomical structure which consists of juxtaglomerular cells, extraglomerular mesangial cells and the macula densa. The juxtaglomerular apparatus lies adjacent to the glomerulus and regulates kidney function by maintaining the blood flow to the kidney and the filtration rate.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-03-18T11:17:47Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072206") +AnnotationAssertion(rdfs:label "metanephric juxtaglomerular apparatus development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (metanephric epithelium development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of an epithelium in the metanephros over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-03-18T11:50:37Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072207") +AnnotationAssertion(rdfs:label "metanephric epithelium development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (metanephric smooth muscle tissue development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of smooth muscle in the metanephros over time, from its formation to the mature structure.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-03-18T11:51:59Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072208") +AnnotationAssertion(rdfs:label "metanephric smooth muscle tissue development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (metanephric nephron development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of a nephron in the metanephros over time, from its formation to the mature structure. A nephron is the functional unit of the kidney.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-03-18T12:52:57Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072210") +AnnotationAssertion(rdfs:label "metanephric nephron development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (metanephric pyramids development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the metanephric pyramids over time, from their formation to the mature structures. Metanephric pyramids are the conical masses that constitute the renal medulla in a metanephros; they contain the loops of Henle and the medullary collecting ducts.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-03-18T01:04:51Z") +AnnotationAssertion(Annotation( "GOC:mah") "metanephric kidney pyramid development") +AnnotationAssertion(Annotation( "GOC:mah") "metanephric pyramid development") +AnnotationAssertion(Annotation( "GOC:mah") "metanephric renal medulla development") +AnnotationAssertion(Annotation( "GOC:mah") "metanephric renal pyramid development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072211") +AnnotationAssertion(rdfs:label "metanephric pyramids development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (metanephric capsule development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the metanephric capsule over time, from its formation to the mature structure. The metanephric capsule is the tough fibrous layer surrounding the metanephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-03-18T01:25:19Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072213") +AnnotationAssertion(rdfs:label "metanephric capsule development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (metanephric cortex development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the metanephric cortex over time, from its formation to the mature structure. The metanephric cortex is the outer region of the metanephros.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-03-18T01:29:49Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072214") +AnnotationAssertion(rdfs:label "metanephric cortex development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (regulation of metanephros development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "Any process that modulates the rate, frequency or extent of metanephros development. Metanephros development is the process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. The metanephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072215") +AnnotationAssertion(rdfs:label "regulation of metanephros development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of metanephros development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "Any process that increases the rate, frequency or extent of metanephros development. Metanephros development is the process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. The metanephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-03-18T01:40:12Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072216") +AnnotationAssertion(rdfs:label "positive regulation of metanephros development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of metanephros development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "Any process that decreases the rate, frequency or extent of metanephros development. Metanephros development is the process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. The metanephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-03-18T01:45:48Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072217") +AnnotationAssertion(rdfs:label "negative regulation of metanephros development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (metanephric ascending thin limb development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of a metanephric ascending thin limb over time, from its formation to the mature structure. The metanephric ascending thin limb is a segment of a nephron tubule in the metanephros lying in the inner medulla that is permeable to ions but not to water and has a simple epithelium; active transepithelial solute transport is absent.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-03-18T03:34:42Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072218") +AnnotationAssertion(rdfs:label "metanephric ascending thin limb development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (metanephric cortical collecting duct development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the metanephric cortical collecting duct over time, from its formation to the mature structure. The metanephric cortical collecting duct is the portion of the metanephric collecting duct that resides in the renal cortex.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-03-18T03:34:52Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072219") +AnnotationAssertion(rdfs:label "metanephric cortical collecting duct development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (metanephric descending thin limb development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the metanephric descending thin limb over time, from its formation to the mature structure. The metanephric descending thin limb is a part of the metanephric loop of Henle situated just after the proximal straight tubule (S3). It extends to the tip of the metanephric loop of Henle.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-03-18T03:35:05Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072220") +AnnotationAssertion(rdfs:label "metanephric descending thin limb development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (metanephric distal convoluted tubule development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the metanephric distal convoluted tubule over time, from its formation to the mature structure. The metanephric distal convoluted tubule is the first segment of the metanephric nephron lying just downstream from the loop of Henle, immediately after the macula densa. Among other functions, in humans it is responsible for the reabsorption of about 5% of filtered sodium via the thiazide-sensitive Na-Cl symporter.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-03-18T03:35:27Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072221") +AnnotationAssertion(rdfs:label "metanephric distal convoluted tubule development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (metanephric early distal convoluted tubule development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the metanephric early distal convoluted tubule over time, from its formation to the mature structure. The metanephric early distal convoluted tubule contains metanephric DCT cells and is vasopressin-insensitive.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-03-18T03:35:46Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072222") +AnnotationAssertion(rdfs:label "metanephric early distal convoluted tubule development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (metanephric glomerular mesangium development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the metanephric glomerular mesangium over time, from its formation to the mature structure. The metanephric glomerular mesangium is the thin membrane connective tissue composed of mesangial cells in the metanephros, which helps to support the capillary loops in a renal glomerulus.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-03-18T03:35:56Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072223") +AnnotationAssertion(rdfs:label "metanephric glomerular mesangium development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (metanephric glomerulus development) + +AnnotationAssertion(Annotation( "GOC:mah") "The progression of the metanephric glomerulus over time from its initial formation until its mature state. The metanephric glomerulus is a capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the mature vertebrate kidney, or metanephros.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-03-18T03:36:20Z") +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "metanephric glomerular development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072224") +AnnotationAssertion(rdfs:label "metanephric glomerulus development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (metanephric late distal convoluted tubule development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the metanephric late distal convoluted tubule over time, from its formation to the mature structure. The metanephric late distal convoluted tubule contains metanephric DCT cells and intercalated (IC) alpha and beta cells and is vasopressin-sensitive.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-03-18T03:37:04Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072225") +AnnotationAssertion(rdfs:label "metanephric late distal convoluted tubule development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (metanephric long descending thin limb bend development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the metanephric long descending thin limb bend over time, from its formation to the mature structure. The metanephric long descending thin limb bend is a part of the descending thin limb of a long nephron that lies beyond the prebend segment in the metanephros.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-03-18T03:37:16Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072226") +AnnotationAssertion(rdfs:label "metanephric long descending thin limb bend development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (metanephric macula densa development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the metanephric macula densa over time, from its formation to the mature structure. The metanephric macula densa is an area of specialized cells in the distal tubule of the metanephros that makes contact with the vascular pole of the glomerulus.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-03-18T03:37:26Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072227") +AnnotationAssertion(rdfs:label "metanephric macula densa development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (metanephric prebend segment development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the metanephric prebend segment over time, from its formation to the mature structure. The metanephric prebend segment is a part of the metanephric descending thin limb that lies before the bend and exhibits permeabilities characteristic of the ascending limb, especially negligible water permeability.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-03-18T03:37:46Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072228") +AnnotationAssertion(rdfs:label "metanephric prebend segment development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (metanephric proximal convoluted tubule development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the metanephric proximal convoluted tubule over time, from its formation to the mature structure. The metanephric proximal convoluted tubule is the most proximal portion of the metanephric proximal tubule and extends from the metanephric glomerular capsule to the metanephric proximal straight tubule.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-03-18T03:37:56Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072229") +AnnotationAssertion(rdfs:label "metanephric proximal convoluted tubule development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (metanephric proximal straight tubule development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the metanephric proximal straight tubule over time, from its formation to the mature structure. The metanephric proximal straight tubule is the part of the metanephric descending limb that extends from the metanephric proximal convoluted tubule to the metanephric descending thin tubule.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-03-18T03:38:53Z") +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "metanephric S3 development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072230") +AnnotationAssertion(rdfs:label "metanephric proximal straight tubule development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (metanephric proximal convoluted tubule segment 1 development) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the S1 portion of the metanephric proximal convoluted tubule over time, from its formation to the mature structure. The S1 portion is the initial portion of the metanephric proximal convoluted tubule and is responsible for avid reabsorption of water and solutes.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-03-18T03:39:10Z") +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "metanephric S1 development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072231") +AnnotationAssertion(rdfs:label "metanephric proximal convoluted tubule segment 1 development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (metanephric thick ascending limb development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the metanephric thick ascending limb over time, from its formation to the mature structure. The metanephric thick ascending limb is the last part of the metanephric loop of Henle. Its thick, mitochondria-rich epithelium characterizes the outer medulla, and is responsible for very avid active salt transport. At the macula densa, the thick ascending limb connects to the distal convoluted tubule.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-03-18T03:39:36Z") +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "metanephric TAL development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072233") +AnnotationAssertion(rdfs:label "metanephric thick ascending limb development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (metanephric nephron tubule development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The progression of a metanephric nephron tubule over time, from its initial formation to the mature structure. A metanephric nephron tubule is an epithelial tube that is part of the metanephric nephron, the functional part of the metanephros.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-03-18T03:41:23Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072234") +AnnotationAssertion(rdfs:label "metanephric nephron tubule development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (metanephric distal tubule development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the metanephric distal tubule over time, from its formation to the mature structure. The metanephric distal tubule is a metanephric nephron tubule that begins at the metanephric macula densa and extends to the metanephric connecting tubule.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-03-18T03:45:37Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072235") +AnnotationAssertion(rdfs:label "metanephric distal tubule development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (metanephric loop of Henle development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the metanephric loop of Henle over time, from its formation to the mature structure. The metanephric loop of Henle is a metanephric nephron tubule that connects the proximal convoluted tubule to the distal convoluted tubule in the metanephros.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-03-18T03:46:18Z") +AnnotationAssertion( "metanephric intermediate tubule development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072236") +AnnotationAssertion(rdfs:label "metanephric loop of Henle development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (metanephric proximal tubule development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the metanephric proximal tubule over time, from its formation to the mature structure. The metanephric proximal tubule is a metanephric nephron tubule that connects Bowman's capsule to the descending thin limb of the loop of Henle in the metanephros. It has a brush border epithelial morphology.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-03-18T03:46:54Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072237") +AnnotationAssertion(rdfs:label "metanephric proximal tubule development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (metanephric long nephron development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of a metanephric long nephron over time, from its formation to the mature structure. Long nephrons are associated with juxtamedullary glomeruli and extend into the inner medulla in the metanephros.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-03-18T03:48:23Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "metanephric juxtamedullary nephron development") +AnnotationAssertion( "GO:0072238") +AnnotationAssertion(rdfs:label "metanephric long nephron development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (metanephric glomerulus vasculature development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The biological process whose specific outcome is the progression of a metanephric glomerulus vasculature from an initial condition to its mature state. This process begins with the formation of the metanephric glomerulus vasculature and ends with the mature structure. The metanephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the metanephric glomerulus.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-03-18T03:50:29Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "glomerulus capillary development") +AnnotationAssertion( "GO:0072239") +AnnotationAssertion(rdfs:label "metanephric glomerulus vasculature development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (metanephric nephron epithelium development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the metanephric nephron epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The metanephric nephron epithelium is a tissue that covers the surface of a nephron in the metanephros.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-03-19T03:29:49Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072243") +AnnotationAssertion(rdfs:label "metanephric nephron epithelium development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (metanephric glomerular epithelium development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the metanephric glomerular epithelium over time, from its formation to the mature structure. The metanephric glomerular epithelium is an epithelial tissue that covers the outer surfaces of the glomerulus in the metanephros. The metanephric glomerular epithelium consists of both parietal and visceral epithelium. Metanephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the metanephros.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-03-19T03:38:47Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072244") +AnnotationAssertion(rdfs:label "metanephric glomerular epithelium development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (metanephric podocyte differentiation) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which a relatively unspecialized cell acquires specialized features of a metanephric glomerular visceral epithelial cell. A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the metanephros.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/23000"^^xsd:anyURI) +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-03-19T03:44:57Z") +AnnotationAssertion( "metanephric glomerular visceral epithelial cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072248") +AnnotationAssertion(rdfs:label "metanephric podocyte differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (metanephric podocyte development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of a metanephric glomerular visceral epithelial cell over time, from its formation to the mature structure. A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the metanephros.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/23000"^^xsd:anyURI) +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-03-19T03:46:26Z") +AnnotationAssertion( "metanephric glomerular visceral epithelial cell development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072249") +AnnotationAssertion(rdfs:label "metanephric podocyte development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (metanephric nephron tubule epithelial cell differentiation) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the metanephric nephron tubule as it progresses from its formation to the mature state.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-03-19T04:11:02Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072257") +AnnotationAssertion(rdfs:label "metanephric nephron tubule epithelial cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (metanephric glomerular endothelium development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the metanephric glomerular endothelium over time, from its formation to the mature structure. The metanephric glomerular endothelium is an epithelial tissue that covers the internal surfaces of the glomerulus of the metanephros.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-03-30T02:42:26Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072264") +AnnotationAssertion(rdfs:label "metanephric glomerular endothelium development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (metanephric capsule morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the anatomical structures of the metanephric capsule are generated and organized. The metanephric capsule is the tough fibrous layer surrounding the metanephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-03-30T02:54:49Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072265") +AnnotationAssertion(rdfs:label "metanephric capsule morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (metanephric capsule formation) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The developmental process pertaining to the initial formation of a metanephric capsule from unspecified parts. The metanephric capsule is the tough fibrous layer surrounding the metanephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-03-30T02:56:35Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072266") +AnnotationAssertion(rdfs:label "metanephric capsule formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (pattern specification involved in metanephros development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "Any developmental process that results in the creation of defined areas or spaces within the metanephros to which cells respond and eventually are instructed to differentiate.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-03-30T03:06:30Z") +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "metanephros pattern specification") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "metanephros pattern formation") +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "pattern formation involved in metanephros development") +AnnotationAssertion( "GO:0072268") +AnnotationAssertion(rdfs:label "pattern specification involved in metanephros development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (metanephric long descending thin limb development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the metanephric long descending thin limb over time, from its formation to the mature structure. The metanephric long descending thin limb is the descending thin limb of a long nephron in the metanephros that has a squamous epithelial morphology. The long descending limb starts in the inner stripe of the outer medulla and extends into the inner medulla.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-03-30T03:12:05Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072269") +AnnotationAssertion(rdfs:label "metanephric long descending thin limb development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (metanephric short nephron development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of a short nephron in the metanephros over time, from its formation to the mature structure. Short nephrons are associated with mid-cortical and superficial glomeruli, are situated entirely in the outer medulla, and have no thin ascending limb.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-03-30T03:15:18Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072270") +AnnotationAssertion(rdfs:label "metanephric short nephron development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (metanephric short descending thin limb development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the metanephric short descending thin limb over time, from its formation to the mature structure. The metanephric short descending thin limb is the descending thin limb of a short nephron in the metanephros that has a squamous epithelial morphology.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-03-30T03:16:25Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072271") +AnnotationAssertion(rdfs:label "metanephric short descending thin limb development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (metanephric nephron morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the anatomical structures of the metanephric nephron are generated and organized. A metanephric nephron is the functional unit of the metanephros.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-03-30T03:33:19Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072273") +AnnotationAssertion(rdfs:label "metanephric nephron morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (metanephric glomerulus morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the anatomical structures of the metanephric glomerulus are generated and organized. The metanephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney, or metanephros.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-04-01T02:46:58Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072275") +AnnotationAssertion(rdfs:label "metanephric glomerulus morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (metanephric glomerulus vasculature morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the anatomical structures of the metanephric glomerulus vasculature are generated and organized. The metanephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the metanephric glomerulus.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-04-01T02:47:32Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072276") +AnnotationAssertion(rdfs:label "metanephric glomerulus vasculature morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (metanephric glomerular capillary formation) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process that gives rise to a metanephric glomerular capillary. This process pertains to the initial formation of a structure from unspecified parts.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-04-01T02:47:56Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072277") +AnnotationAssertion(rdfs:label "metanephric glomerular capillary formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (metanephric comma-shaped body morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the metanephric comma-shaped body is generated and organized. The metanephric comma-shaped body is the precursor structure to the metanephric S-shaped body that contributes to the morphogenesis of a nephron in the metanephros.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-04-01T03:14:42Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072278") +AnnotationAssertion(rdfs:label "metanephric comma-shaped body morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (metanephric nephron tubule morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the anatomical structures of a metanephric nephron tubule are generated and organized. A metanephric nephron tubule is an epithelial tube that is part of the metanephric nephron, the functional part of the metanephros.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-04-01T03:25:11Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072282") +AnnotationAssertion(rdfs:label "metanephric nephron tubule morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (metanephric renal vesicle morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the anatomical structures of the metanephric renal vesicle are generated and organized. The renal vesicle is the primordial structure of the metanephric nephron epithelium, and is formed by the condensation of mesenchymal cells.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-04-01T03:28:00Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072283") +AnnotationAssertion(rdfs:label "metanephric renal vesicle morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (metanephric S-shaped body morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the metanephric S-shaped body is generated and organized. The metanephric S-shaped body is the successor of the metanephric comma-shaped body that contributes to the morphogenesis of a nephron in the metanephros.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-04-01T03:41:36Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072284") +AnnotationAssertion(rdfs:label "metanephric S-shaped body morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (mesenchymal to epithelial transition involved in metanephric renal vesicle formation) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephric renal vesicle.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-04-01T03:43:31Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072285") +AnnotationAssertion(rdfs:label "mesenchymal to epithelial transition involved in metanephric renal vesicle formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (metanephric connecting tubule development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of the metanephric connecting tubule over time, from its formation to the mature structure. The metanephric connecting tubule is a tubular segment of the metanephric nephron; it connects the distal convoluted tubule to the collecting duct in the metanephros.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-04-09T03:30:09Z") +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "metanephric connecting duct development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072286") +AnnotationAssertion(rdfs:label "metanephric connecting tubule development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (metanephric distal tubule morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the anatomical structures of a metanephric distal tubule are generated and organized. The metanephric distal tubule is a metanephric nephron tubule that begins at the macula densa and extends to the metanephric connecting tubule.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-04-09T03:41:47Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072287") +AnnotationAssertion(rdfs:label "metanephric distal tubule morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (metanephric proximal tubule morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which the anatomical structures of a metanephric proximal tubule are generated and organized. The metanephric proximal tubule is a metanephric nephron tubule that connects Bowman's capsule to the descending thin limb of the loop of Henle in the metanephros. It has a brush border epithelial morphology.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-04-09T03:42:03Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072288") +AnnotationAssertion(rdfs:label "metanephric proximal tubule morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (metanephric nephron tubule formation) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The developmental process pertaining to the initial formation of a metanephric nephron tubule from unspecified parts. A metanephric nephron tubule is an epithelial tube that is part of a nephron in the metanephros.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-04-09T03:47:44Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072289") +AnnotationAssertion(rdfs:label "metanephric nephron tubule formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (epithelial cell migration involved in metanephric nephron tubule morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The orderly movement of epithelial cells within a renal tubule that contributes to metanephric nephron tubule morphogenesis.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-04-09T03:52:29Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072290") +AnnotationAssertion(rdfs:label "epithelial cell migration involved in metanephric nephron tubule morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (epithelial cell migration involved in metanephric distal tubule morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The orderly movement of epithelial cells within a renal tubule that contributes to metanephric distal tubule morphogenesis.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-04-09T03:53:37Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072291") +AnnotationAssertion(rdfs:label "epithelial cell migration involved in metanephric distal tubule morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (epithelial cell migration involved in metanephric proximal tubule morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The orderly movement of epithelial cells within a renal tubule that contributes to metanephric proximal tubule morphogenesis.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-04-09T03:54:28Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072292") +AnnotationAssertion(rdfs:label "epithelial cell migration involved in metanephric proximal tubule morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of metanephric glomerulus development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "Any process that modulates the rate, frequency or extent of metanephric glomerulus development, the progression of the metanephric glomerulus over time from its initial formation until its mature state. The metanephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney, or metanephros.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-04-09T05:03:14Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072298") +AnnotationAssertion(rdfs:label "regulation of metanephric glomerulus development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (negative regulation of metanephric glomerulus development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "Any process that decreases the rate, frequency or extent of metanephric glomerulus development, the progression of the metanephric glomerulus over time from its initial formation until its mature state. The metanephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney, or metanephros.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-04-09T05:03:41Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072299") +AnnotationAssertion(rdfs:label "negative regulation of metanephric glomerulus development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (positive regulation of metanephric glomerulus development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "Any process that increases the rate, frequency or extent of metanephric glomerulus development, the progression of the metanephric glomerulus over time from its initial formation until its mature state. The metanephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney, or metanephros.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-04-09T05:03:41Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072300") +AnnotationAssertion(rdfs:label "positive regulation of metanephric glomerulus development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:mtg_kidney_jan10") "Any process that modulates the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the metanephros.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-04-09T05:03:41Z") +AnnotationAssertion( "regulation of mesenchymal stem cell apoptotic process involved in metanephric nephron morphogenesis") +AnnotationAssertion( "regulation of mesenchymal stem cell apoptosis involved in metanephric nephron morphogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072304") +AnnotationAssertion(rdfs:label "regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:mtg_kidney_jan10") "Any process that reduces the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the metanephros.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-04-09T05:03:41Z") +AnnotationAssertion( "negative regulation of mesenchymal stem cell apoptotic process involved in metanephric nephron morphogenesis") +AnnotationAssertion( "negative regulation of mesenchymal stem cell apoptosis involved in metanephric nephron morphogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072305") +AnnotationAssertion(rdfs:label "negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (positive regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:mtg_kidney_jan10") "Any process that increases the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the metanephros.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-04-09T05:03:41Z") +AnnotationAssertion( "positive regulation of mesenchymal stem cell apoptotic process involved in metanephric nephron morphogenesis") +AnnotationAssertion( "positive regulation of mesenchymal stem cell apoptosis involved in metanephric nephron morphogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072306") +AnnotationAssertion(rdfs:label "positive regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (regulation of metanephric nephron tubule epithelial cell differentiation) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "Any process that modulates the frequency, rate or extent of metanephric nephron tubule epithelial cell differentiation.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-04-09T05:03:41Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072307") +AnnotationAssertion(rdfs:label "regulation of metanephric nephron tubule epithelial cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of metanephric nephron tubule epithelial cell differentiation) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "Any process that decreases the frequency, rate or extent of metanephric nephron tubule epithelial cell differentiation.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-04-09T05:03:41Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072308") +AnnotationAssertion(rdfs:label "negative regulation of metanephric nephron tubule epithelial cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which an organism retains a population of mesenchymal stem cells that contributes to the shaping of a nephron in the metanephros. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-04-09T05:03:41Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072309") +AnnotationAssertion(rdfs:label "mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (glomerular epithelial cell development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of a glomerular epithelial cell over time, from its formation to the mature structure. Glomerular epithelial cells are specialized epithelial cells that form part of the glomerulus; there are two types, glomerular parietal epithelial cells and glomerular visceral epithelial cells.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-04-09T06:47:31Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072310") +AnnotationAssertion(rdfs:label "glomerular epithelial cell development") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (glomerular epithelial cell differentiation) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which a relatively unspecialized cell acquires specialized features of a glomerular epithelial cell. Glomerular epithelial cells are specialized epithelial cells that form part of the glomerulus; there are two types, glomerular parietal epithelial cells and glomerular visceral epithelial cells.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-04-09T06:49:21Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072311") +AnnotationAssertion(rdfs:label "glomerular epithelial cell differentiation") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (metanephric glomerular epithelial cell differentiation) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process in which a relatively unspecialized cell acquires specialized features of a metanephric glomerular epithelial cell. Metanephric glomerular epithelial cells are specialized epithelial cells that form part of the metanephric glomerulus; there are two types, metanephric glomerular parietal epithelial cells and metanephric glomerular visceral epithelial cells.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-04-09T06:54:15Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072312") +AnnotationAssertion(rdfs:label "metanephric glomerular epithelial cell differentiation") +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (metanephric glomerular epithelial cell development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "The process whose specific outcome is the progression of a metanephric glomerular epithelial cell over time, from its formation to the mature structure. Metanephric glomerular epithelial cells are specialized epithelial cells that form part of the metanephric glomerulus; there are two types, metanephric glomerular parietal epithelial cells and metanephric glomerular visceral epithelial cells.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-04-09T06:57:26Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072313") +AnnotationAssertion(rdfs:label "metanephric glomerular epithelial cell development") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (monocarboxylic acid catabolic process) + +AnnotationAssertion(Annotation( "GOC:mah") "The chemical reactions and pathways resulting in the breakdown of monocarboxylic acids, any organic acid containing one carboxyl (-COOH) group.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-11-02T04:41:55Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072329") +AnnotationAssertion(rdfs:label "monocarboxylic acid catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (monocarboxylic acid biosynthetic process) AnnotationAssertion(Annotation( "GOC:mah") "The chemical reactions and pathways resulting in the formation of monocarboxylic acids, any organic acid containing one carboxyl (-COOH) group.") @@ -40502,9 +108833,439 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:0072330") AnnotationAssertion(rdfs:label "monocarboxylic acid biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) +# Class: (modified amino acid transport) + +AnnotationAssertion(Annotation( "GOC:mah") "The directed movement of modified amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-11-04T12:18:23Z") +AnnotationAssertion( "amino acid derivative transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072337") +AnnotationAssertion(rdfs:label "modified amino acid transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (modified amino acid binding) + +AnnotationAssertion(Annotation( "GOC:mah") "Binding to a modified amino acid.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-11-04T05:45:32Z") +AnnotationAssertion( "amino acid derivative binding") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0072341") +AnnotationAssertion(rdfs:label "modified amino acid binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (sulfur compound transport) + +AnnotationAssertion(Annotation( "GOC:mah") "The directed movement of compounds that contain sulfur, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-11-11T11:43:56Z") +AnnotationAssertion(Annotation( "GOC:mah") "sulfur-containing compound transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072348") +AnnotationAssertion(rdfs:label "sulfur compound transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (modified amino acid transmembrane transporter activity) + +AnnotationAssertion(Annotation( "GOC:mah") "Enables the transfer of modified amino acids from one side of a membrane to the other.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-11-11T11:50:31Z") +AnnotationAssertion(Annotation( "GOC:mah") "modified amino acid transporter activity") +AnnotationAssertion( "amino acid derivative transmembrane transporter activity") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0072349") +AnnotationAssertion(rdfs:label "modified amino acid transmembrane transporter activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (circulatory system development) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "UBERON:0001009") "The process whose specific outcome is the progression of the circulatory system over time, from its formation to the mature structure. The circulatory system is the organ system that passes nutrients (such as amino acids and electrolytes), gases, hormones, blood cells, etc. to and from cells in the body to help fight diseases and help stabilize body temperature and pH to maintain homeostasis.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-11-16T11:27:39Z") +AnnotationAssertion( "GO:0072358") +AnnotationAssertion( "cardiovascular system development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072359") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "circulatory system development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (vascular cord development) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "PMID:7084422") Annotation( "ZFA:0005077") "The progression of the vascular cord over time from its initial formation until its mature state. The vascular cord is the primordial vasculature that will develop into blood vessels by the process of tubulogenesis.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-11-16T11:46:55Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072360") +AnnotationAssertion(rdfs:label "vascular cord development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (organelle transport along microtubule) + +AnnotationAssertion(Annotation( "GOC:mah") "The directed movement of an organelle along a microtubule, mediated by motor proteins. This process begins with the attachment of an organelle to a microtubule, and ends when the organelle reaches its final destination.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-12-01T04:59:11Z") +AnnotationAssertion(Annotation( "GOC:rl") "microtubule-based organelle localization") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072384") +AnnotationAssertion(rdfs:label "organelle transport along microtubule") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (ammonium transmembrane transport) + +AnnotationAssertion(Annotation( "GOC:mah") "The process in which ammonium is transported across a membrane. Ammonium is the cation NH4+.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/22228"^^xsd:anyURI) +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-12-10T10:29:57Z") +AnnotationAssertion( "GO:0015696") +AnnotationAssertion( "ammonia transport") +AnnotationAssertion( "ammonium transport") +AnnotationAssertion( "ammonium membrane transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072488") +AnnotationAssertion(rdfs:comment "Note that this term is not intended for use in annotating lateral movement within membranes.") +AnnotationAssertion(rdfs:label "ammonium transmembrane transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (seminiferous tubule development) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mah") Annotation( "UBERON:0001343") "The reproductive developmental process whose specific outcome is the progression of the seminiferous tubule over time, from its formation to the mature structure. Seminiferous tubules are ducts located in the testicles, and are the specific location of meiosis, and the subsequent creation of gametes, namely spermatozoa.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2011-01-04T12:50:36Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072520") +AnnotationAssertion(rdfs:label "seminiferous tubule development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (purine-containing compound metabolic process) + +AnnotationAssertion(Annotation( "GOC:mah") "The chemical reactions and pathways involving a purine-containing compound, i.e. any compound that contains purine or a formal derivative thereof.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2011-01-04T03:03:59Z") +AnnotationAssertion( "purine and derivative metabolic process") +AnnotationAssertion(Annotation( "GOC:mah") "purine-containing compound metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072521") +AnnotationAssertion(rdfs:label "purine-containing compound metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (purine-containing compound biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:mah") "The chemical reactions and pathways resulting in the formation of a purine-containing compound, i.e. any compound that contains purine or a formal derivative thereof.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2011-01-04T03:15:29Z") +AnnotationAssertion( "purine and derivative biosynthetic process") +AnnotationAssertion(Annotation( "GOC:mah") "purine-containing compound anabolism") +AnnotationAssertion(Annotation( "GOC:mah") "purine-containing compound biosynthesis") +AnnotationAssertion(Annotation( "GOC:mah") "purine-containing compound formation") +AnnotationAssertion(Annotation( "GOC:mah") "purine-containing compound synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072522") +AnnotationAssertion(rdfs:label "purine-containing compound biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (purine-containing compound catabolic process) + +AnnotationAssertion(Annotation( "GOC:mah") "The chemical reactions and pathways resulting in the breakdown of a purine-containing compound, i.e. any compound that contains purine or a formal derivative thereof.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2011-01-04T03:17:20Z") +AnnotationAssertion( "purine and derivative catabolic process") +AnnotationAssertion(Annotation( "GOC:mah") "purine-containing compound breakdown") +AnnotationAssertion(Annotation( "GOC:mah") "purine-containing compound catabolism") +AnnotationAssertion(Annotation( "GOC:mah") "purine-containing compound degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072523") +AnnotationAssertion(rdfs:label "purine-containing compound catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (purine-containing compound transmembrane transport) + +AnnotationAssertion(Annotation( "GOC:mah") "The process in which a purine-containing compound is transported across a membrane. A purine-containing compound is any compound that contains purine or a formal derivative thereof.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2011-01-05T01:45:14Z") +AnnotationAssertion( "purine-containing compound membrane transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072530") +AnnotationAssertion(rdfs:comment "Note that this term is not intended for use in annotating lateral movement within membranes.") +AnnotationAssertion(rdfs:label "purine-containing compound transmembrane transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (fibroblast activation) + +AnnotationAssertion(Annotation( "CL:0000057") Annotation( "GOC:BHF") Annotation( "GOC:mah") "A change in the morphology or behavior of a fibroblast resulting from exposure to an activating factor such as a cellular or soluble ligand.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2011-01-14T04:35:08Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072537") +AnnotationAssertion(rdfs:label "fibroblast activation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (type B pancreatic cell maturation) + +AnnotationAssertion(Annotation( "CL:0000169") Annotation( "GOC:BHF") "A developmental process, independent of morphogenetic (shape) change, that is required for a type B pancreatic cell to attain its fully functional state. A type B pancreatic cell is a cell located towards center of the islets of Langerhans that secretes insulin.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2011-01-27T01:57:14Z") +AnnotationAssertion(Annotation( "CL:0000169") Annotation( "GOC:mah") "pancreatic B cell maturation") +AnnotationAssertion(Annotation( "CL:0000169") Annotation( "GOC:mah") "pancreatic beta cell maturation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072560") +AnnotationAssertion(rdfs:comment "These processes continue to 60 DPA in Gossypium spp.") +AnnotationAssertion(rdfs:label "type B pancreatic cell maturation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (epithelial cell proliferation involved in liver morphogenesis) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mah") "The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population that contributes to the shaping of the liver.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2011-02-02T03:37:50Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072575") +AnnotationAssertion(rdfs:label "epithelial cell proliferation involved in liver morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (liver morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mah") "The process in which the anatomical structures of the liver are generated and organized.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2011-02-02T03:41:30Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072576") +AnnotationAssertion(rdfs:label "liver morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (endothelial cell apoptotic process) + +AnnotationAssertion(Annotation( "CL:0000115") Annotation( "GOC:BHF") Annotation( "GOC:mah") Annotation( "GOC:mtg_apoptosis") "Any apoptotic process in an endothelial cell. An endothelial cell comprises the outermost layer or lining of anatomical structures and can be squamous or cuboidal.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2011-02-02T03:56:24Z") +AnnotationAssertion(Annotation( "GOC:mah") "apoptosis of endothelial cells") +AnnotationAssertion(Annotation( "GOC:mah") "endothelial cell programmed cell death by apoptosis") +AnnotationAssertion(Annotation( "GOC:mah") "killing of endothelial cells") +AnnotationAssertion(Annotation( "GOC:mah") "programmed cell death of endothelial cells by apoptosis") +AnnotationAssertion(Annotation( "GOC:mah") "programmed cell death, endothelial cells") +AnnotationAssertion( "endothelial cell apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072577") +AnnotationAssertion(rdfs:label "endothelial cell apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (oxygen metabolic process) + +AnnotationAssertion(Annotation( "GOC:mah") "The chemical reactions and pathways involving diatomic oxygen (O2).") +AnnotationAssertion( "mah") +AnnotationAssertion( "2011-02-11T10:46:51Z") +AnnotationAssertion(Annotation( "CHEBI:33263") "diatomic oxygen metabolic process") +AnnotationAssertion(Annotation( "GOC:mah") "oxygen metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072592") +AnnotationAssertion(rdfs:label "oxygen metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (establishment of protein localization to organelle) + +AnnotationAssertion(Annotation( "GOC:mah") "The directed movement of a protein to a specific location on or in an organelle. Encompasses establishment of localization in the membrane or lumen of a membrane-bounded organelle.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2011-02-14T01:56:51Z") +AnnotationAssertion(Annotation( "GOC:mah") "establishment of protein localisation to organelle") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072594") +AnnotationAssertion(rdfs:label "establishment of protein localization to organelle") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (maintenance of protein localization in organelle) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process in which a protein is maintained in a specific location a specific location on or in an organelle, and is prevented from moving elsewhere. Encompasses establishment of localization in the membrane or lumen of a membrane-bounded organelle.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2011-02-14T02:09:13Z") +AnnotationAssertion(Annotation( "GOC:mah") "maintenance of protein localisation to organelle") +AnnotationAssertion( "maintenance of protein localization to organelle") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072595") +AnnotationAssertion(rdfs:label "maintenance of protein localization in organelle") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (protein localization to membrane) + +AnnotationAssertion(Annotation( "GOC:mah") "A process in which a protein is transported to, or maintained in, a specific location in a membrane.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2011-02-14T02:35:18Z") +AnnotationAssertion(Annotation( "GOC:mah") "protein localisation in membrane") +AnnotationAssertion( "protein localization in membrane") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072657") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "protein localization to membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (protein localization to plasma membrane) + +AnnotationAssertion(Annotation( "GOC:mah") "A process in which a protein is transported to, or maintained in, a specific location in the plasma membrane.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2009-07-10T10:29:23Z") +AnnotationAssertion( "GO:0072661") +AnnotationAssertion( "GO:0090002") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:mah") "protein localisation in plasma membrane") +AnnotationAssertion( "protein localization in plasma membrane") +AnnotationAssertion( "protein targeting to plasma membrane") +AnnotationAssertion(Annotation( "GOC:mah") "protein-plasma membrane targeting") +AnnotationAssertion( "GO:0072659") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "protein localization to plasma membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (protein localization to vacuole) + +AnnotationAssertion(Annotation( "GOC:ecd") "A process in which a protein is transported to, or maintained at, a location in a vacuole.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2011-02-14T02:55:35Z") +AnnotationAssertion(Annotation( "GOC:mah") "protein localisation to vacuole") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072665") +AnnotationAssertion(rdfs:label "protein localization to vacuole") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (establishment of protein localization to vacuole) + +AnnotationAssertion(Annotation( "GOC:mah") "The directed movement of a protein to a specific location in a vacuole.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2011-02-14T02:56:29Z") +AnnotationAssertion(Annotation( "GOC:mah") "establishment of protein localisation to vacuole") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072666") +AnnotationAssertion(rdfs:label "establishment of protein localization to vacuole") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (maintenance of protein location in vacuole) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process in which a protein is maintained in a specific location in a vacuole, and is prevented from moving elsewhere.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2011-02-14T02:56:57Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072667") +AnnotationAssertion(rdfs:label "maintenance of protein location in vacuole") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (multinuclear osteoclast differentiation) + +AnnotationAssertion(Annotation( "CL:0000779") Annotation( "GOC:mah") Annotation( "PMID:12713016") "The process in which a relatively unspecialized monocyte acquires the specialized features of a multinuclear osteoclast. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2011-02-22T02:10:38Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mah") "multinuclear osteoclast formation") +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mah") "multinuclear osteoclast morphogenesis") +AnnotationAssertion( "GO:0072674") +AnnotationAssertion(rdfs:label "multinuclear osteoclast differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (lymphocyte migration) + +AnnotationAssertion(Annotation( "CL:0000542") Annotation( "GOC:BHF") Annotation( "GOC:mah") "The movement of a lymphocyte within or between different tissues and organs of the body.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2011-02-22T03:38:12Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072676") +AnnotationAssertion(rdfs:label "lymphocyte migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (T cell migration) + +AnnotationAssertion(Annotation( "CL:0000084") Annotation( "GOC:BHF") Annotation( "GOC:mah") "The movement of a T cell within or between different tissues and organs of the body.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2011-02-22T03:40:40Z") +AnnotationAssertion(Annotation( "CL:0000084") "T lymphocyte migration") +AnnotationAssertion(Annotation( "CL:0000084") "T-cell migration") +AnnotationAssertion(Annotation( "CL:0000084") "T-lymphocyte migration") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072678") +AnnotationAssertion(rdfs:label "T cell migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (thymocyte migration) + +AnnotationAssertion(Annotation( "CL:0000893") Annotation( "GOC:BHF") Annotation( "GOC:mah") "The movement of a thymocyte through distinct intrathymic niches (e.g. medulla, cortex), where it receives a unique set of developmental cues required for T-cell development.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2011-02-22T03:47:51Z") +AnnotationAssertion(Annotation( "CL:0000893") "thymic lymphocyte migration") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "CL:0000893") "immature T cell migration") +AnnotationAssertion(Annotation( "CL:0000893") "immature T lymphocyte migration") +AnnotationAssertion(Annotation( "CL:0000893") "immature T-cell migration") +AnnotationAssertion(Annotation( "CL:0000893") "immature T-lymphocyte migration") +AnnotationAssertion( "GO:0072679") +AnnotationAssertion(rdfs:label "thymocyte migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (protein localization to cell cortex) + +AnnotationAssertion(Annotation( "GOC:mah") "A process in which a protein is transported to, or maintained in, the cell cortex.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2012-04-11T01:16:33Z") +AnnotationAssertion(Annotation( "GOC:mah") "protein localisation to cell cortex") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072697") +AnnotationAssertion(rdfs:label "protein localization to cell cortex") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (protein localization to microtubule cytoskeleton) + +AnnotationAssertion(Annotation( "GOC:mah") "A cellular protein localization process in which a protein is transported to, or maintained at, a location within the microtubule cytoskeleton.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2012-04-11T01:19:35Z") +AnnotationAssertion(Annotation( "GOC:mah") "protein localisation to microtubule cytoskeleton") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0072698") +AnnotationAssertion(rdfs:label "protein localization to microtubule cytoskeleton") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of primary metabolic process) + +AnnotationAssertion(Annotation( "PMID:19211694") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism involving those compounds formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.") +AnnotationAssertion( "dhl") +AnnotationAssertion( "2009-04-22T04:30:52Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0080090") +AnnotationAssertion(rdfs:label "regulation of primary metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + # Class: (regulation of response to stress) AnnotationAssertion(Annotation( "GOC:dhl") "Any process that modulates the frequency, rate or extent of a response to stress. Response to stress is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).") @@ -40515,8 +109276,339 @@ AnnotationAssertion( ) AnnotationAssertion(rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.") AnnotationAssertion(rdfs:label "regulation of response to stress") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (intracellular amino acid homeostasis) + +AnnotationAssertion(Annotation( "PMID:19955263") "A homeostatic process involved in the maintenance of a steady state level of amino acids within a cell.") +AnnotationAssertion( "dhl") +AnnotationAssertion( "2010-01-27T04:47:27Z") +AnnotationAssertion( "amino acid homeostasis") +AnnotationAssertion( "cellular amino acid homeostasis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0080144") +AnnotationAssertion(rdfs:label "intracellular amino acid homeostasis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of fertilization) + +AnnotationAssertion(Annotation( "GOC:DHL") Annotation( "PMID:20478994") "Any process that modulates the rate, frequency or extent of fertilization. Fertilization is the union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy).") +AnnotationAssertion( "dhl") +AnnotationAssertion( "2010-09-01T03:44:27Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0080154") +AnnotationAssertion(rdfs:label "regulation of fertilization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (lytic vacuole organization) + +AnnotationAssertion(Annotation( "PMID:20729380") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lytic vacuole.") +AnnotationAssertion( "dhl") +AnnotationAssertion( "2011-04-25T04:40:46Z") +AnnotationAssertion( "lytic vacuole organisation") +AnnotationAssertion( "lytic vacuolar assembly") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "lytic vacuole biogenesis") +AnnotationAssertion( "lytic vacuole organization and biogenesis") +AnnotationAssertion( "GO:0080171") +AnnotationAssertion(rdfs:label "lytic vacuole organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (extracellular matrix assembly) + +AnnotationAssertion(Annotation( "GOC:jl") "The aggregation, arrangement and bonding together of the extracellular matrix.") +AnnotationAssertion( "jl") +AnnotationAssertion( "2010-07-14T12:52:49Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0085029") +AnnotationAssertion(rdfs:label "extracellular matrix assembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (cardiac muscle cell action potential) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mtg_cardiac_conduct_nov11") "An action potential that occurs in a cardiac muscle cell.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2011-11-10T07:45:11Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0086001") +AnnotationAssertion(rdfs:label "cardiac muscle cell action potential") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (SA node cell action potential) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mtg_cardiac_conduct_nov11") "An action potential that occurs in a sinoatrial node cardiac muscle cell.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2011-11-10T08:50:15Z") +AnnotationAssertion( "SA node cardiac muscle cell action potential") +AnnotationAssertion( "SAN cardiac muscle cell action potential") +AnnotationAssertion( "sinoatrial node cardiac muscle cell action potential") +AnnotationAssertion( "sinus node cardiac muscle cell action potential") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0086015") +AnnotationAssertion(rdfs:label "SA node cell action potential") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (AV node cell action potential) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mtg_cardiac_conduct_nov11") "An action potential that occurs in an atrioventricular node cardiac muscle cell.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2011-11-10T08:58:56Z") +AnnotationAssertion( "AV node cardiac muscle cell action potential") +AnnotationAssertion( "atrioventricular node cardiac muscle cell action potential") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0086016") +AnnotationAssertion(rdfs:label "AV node cell action potential") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (Purkinje myocyte action potential) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mtg_cardiac_conduct_nov11") "An action potential that occurs in a Purkinje myocyte.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2011-11-10T08:58:56Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0086017") +AnnotationAssertion(rdfs:label "Purkinje myocyte action potential") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (SA node cell to atrial cardiac muscle cell signaling) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mtg_cardiac_conduct_nov11") "Any process that mediates the transfer of information from an SA node cardiomyocyte to an atrial cardiomyocyte.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2011-11-10T09:15:01Z") +AnnotationAssertion( "SA node cardiac muscle cell to atrial cardiac muscle cell signalling") +AnnotationAssertion( "SA node cardiomyocyte to atrial cardiomyocyte signalling") +AnnotationAssertion( "SAN cardiomyocyte to atrial cardiomyocyte signalling") +AnnotationAssertion( "sinoatrial node cardiomyocyte to atrial cardiomyocyte signalling") +AnnotationAssertion( "sinus node cardiomyocyte to atrial cardiomyocyte signalling") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0086018") +AnnotationAssertion(rdfs:label "SA node cell to atrial cardiac muscle cell signaling") +SubClassOf( ) +SubClassOf( ) + +# Class: (cell-cell signaling involved in cardiac conduction) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mtg_cardiac_conduct_nov11") "Any process that mediates the transfer of information from one cell to another and contributes to the heart process that regulates cardiac muscle contraction; beginning with the generation of an action potential in the sinoatrial node and ending with regulation of contraction of the myocardium.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2011-11-16T03:43:52Z") +AnnotationAssertion(Annotation( "GOC:mah") "cell-cell signalling involved in cardiac conduction") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0086019") +AnnotationAssertion(rdfs:label "cell-cell signaling involved in cardiac conduction") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (AV node cell to bundle of His cell signaling) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mtg_cardiac_conduct_nov11") "Any process that mediates the transfer of information from an AV node cardiac muscle cell to a bundle of His cardiomyocyte.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2011-11-11T02:02:14Z") +AnnotationAssertion(Annotation( "GOC:mah") "AV node cell to bundle of His cell signalling") +AnnotationAssertion( "atrioventricular node to bundle of His cell signaling") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0086027") +AnnotationAssertion(rdfs:label "AV node cell to bundle of His cell signaling") +SubClassOf( ) +SubClassOf( ) + +# Class: (bundle of His cell to Purkinje myocyte signaling) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mtg_cardiac_conduct_nov11") "Any process that mediates the transfer of information from a bundle of His cardiomyocyte to a Purkinje myocyte.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2011-11-11T02:02:14Z") +AnnotationAssertion( "bundle of His cardiac muscle cell to Purkinje myocyte signaling") +AnnotationAssertion(Annotation( "GOC:mah") "bundle of His cardiac muscle cell to Purkinje myocyte signalling") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0086028") +AnnotationAssertion(rdfs:label "bundle of His cell to Purkinje myocyte signaling") +SubClassOf( ) +SubClassOf( ) + +# Class: (Purkinje myocyte to ventricular cardiac muscle cell signaling) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mtg_cardiac_conduct_nov11") "Any process that mediates the transfer of information from a Purkinje myocyte to a ventricular cardiac muscle cell.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2011-11-11T02:02:14Z") +AnnotationAssertion(Annotation( "GOC:mah") "Purkinje myocyte to ventricular cardiac muscle cell signalling") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0086029") +AnnotationAssertion(rdfs:label "Purkinje myocyte to ventricular cardiac muscle cell signaling") +SubClassOf( ) +SubClassOf( ) + +# Class: (bundle of His cell action potential) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mtg_cardiac_conduct_nov11") "An action potential that occurs in a bundle of His cell.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2011-11-15T12:01:18Z") +AnnotationAssertion( "bundle of His cardiac muscle cell action potential") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0086043") +AnnotationAssertion(rdfs:label "bundle of His cell action potential") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cell communication involved in cardiac conduction) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mtg_cardiac_conduct_nov11") "Any process that mediates interactions between a cell and its surroundings that contributes to the process of cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2011-11-22T08:57:02Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0086065") +AnnotationAssertion(rdfs:label "cell communication involved in cardiac conduction") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (AV node cell to bundle of His cell communication) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mtg_cardiac_conduct_nov11") "The process that mediates interactions between an AV node cell and its surroundings that contributes to the process of the AV node cell communicating with a bundle of His cell in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2011-11-22T09:11:44Z") +AnnotationAssertion( "atrioventricular node cell to bundle of His cell communication") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0086067") +AnnotationAssertion(rdfs:label "AV node cell to bundle of His cell communication") +SubClassOf( ) + +# Class: (Purkinje myocyte to ventricular cardiac muscle cell communication) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mtg_cardiac_conduct_nov11") "The process that mediates interactions between a Purkinje myocyte and its surroundings that contributes to the process of the Purkinje myocyte communicating with a ventricular cardiac muscle cell in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2011-11-22T09:14:49Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0086068") +AnnotationAssertion(rdfs:label "Purkinje myocyte to ventricular cardiac muscle cell communication") +SubClassOf( ) + +# Class: (bundle of His cell to Purkinje myocyte communication) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mtg_cardiac_conduct_nov11") "The process that mediates interactions between a bundle of His cell and its surroundings that contributes to the process of the bundle of His cell communicating with a Purkinje myocyte in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/20731"^^xsd:anyURI) +AnnotationAssertion( "dph") +AnnotationAssertion( "2011-11-22T09:18:49Z") +AnnotationAssertion( "bundle of His cardiac muscle cell to Purkinje myocyte communication") +AnnotationAssertion( "ventricular conduction system cell to cell communication") +AnnotationAssertion( "atrioventricular junction myocyte to bundle branch myocyte") +AnnotationAssertion( "bundle branch myocyte to Purkinje myocyte communication") +AnnotationAssertion( "bundle of His myocyte to atrioventricular junction myocyte") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0086069") +AnnotationAssertion(rdfs:label "bundle of His cell to Purkinje myocyte communication") +SubClassOf( ) + +# Class: (SA node cell to atrial cardiac muscle cell communication) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mtg_cardiac_conduct_nov11") "The process that mediates interactions between an SA node cardiomyocyte and its surroundings that contributes to the process of the SA node cardiomyocyte communicating with an atrial cardiomyocyte in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2011-11-22T09:32:45Z") +AnnotationAssertion( "SA node cardiac muscle cell to atrial cardiac muscle cell communication") +AnnotationAssertion( "SA node cardiomyocyte to atrial cardiomyocyte communication") +AnnotationAssertion( "SAN cardiomyocyte to atrial cardiomyocyte communication") +AnnotationAssertion( "sinoatrial node cardiomyocyte to atrial cardiomyocyte communication") +AnnotationAssertion( "sinus node cardiomyocyte to atrial cardiomyocyte communication") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0086070") +AnnotationAssertion(rdfs:label "SA node cell to atrial cardiac muscle cell communication") +SubClassOf( ) + +# Class: (G protein-coupled acetylcholine receptor signaling pathway involved in heart process) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mtg_cardiac_conduct_nov11") "A G protein-coupled acetylcholine receptor signaling pathway, which contributes to a circulatory system process carried out by the heart.") +AnnotationAssertion( "bf") +AnnotationAssertion( "G-protein coupled acetylcholine receptor signaling pathway involved in heart process") +AnnotationAssertion(Annotation( "GOC:bf") "G-protein coupled acetylcholine receptor signalling pathway involved in heart process") +AnnotationAssertion(Annotation( "GOC:mtg_cardiac_conduct_nov11") "M2 receptor signaling pathway involved in heart process") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:mtg_cardiac_conduct_nov11") "muscarinic receptor signaling pathway involved in heart process") +AnnotationAssertion( "GO:0086093") +AnnotationAssertion(rdfs:label "G protein-coupled acetylcholine receptor signaling pathway involved in heart process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (G protein-coupled receptor signaling pathway involved in heart process) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mtg_cardiac_conduct_nov11") Annotation( "PMID:17376402") "An G protein-coupled receptor signaling pathway which contributes to a circulatory system process carried out by the heart.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2012-03-19T01:28:23Z") +AnnotationAssertion(Annotation( "GOC:bf") "G-protein coupled receptor signaling pathway involved in heart process") +AnnotationAssertion(Annotation( "GOC:bf") "G-protein coupled receptor signalling pathway involved in heart process") +AnnotationAssertion(Annotation( "GOC:bf") "GPCR signaling pathway involved in cardiac process") +AnnotationAssertion(Annotation( "GOC:bf") "GPCR signaling pathway involved in heart process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0086103") +AnnotationAssertion(rdfs:label "G protein-coupled receptor signaling pathway involved in heart process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (L-glutamate transmembrane export from vacuole) + +AnnotationAssertion(Annotation( "PMID:21307582") "The directed movement of L-glutamate out of the vacuole, across the vacuolar membrane.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0089704") +AnnotationAssertion(rdfs:label "L-glutamate transmembrane export from vacuole") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (amino acid import across plasma membrane) + +AnnotationAssertion(Annotation( "GOC:krc") Annotation( "PMID:8195186") "The directed movement of an amino acid from outside of a cell, across the plasma membrane and into the cytosol.") +AnnotationAssertion( "jl") +AnnotationAssertion( "2012-11-14T14:21:41Z") +AnnotationAssertion( "GO:0043092") +AnnotationAssertion( "GO:0044745") +AnnotationAssertion( "GO:1902837") +AnnotationAssertion( "L-amino acid import") +AnnotationAssertion( "amino acid transmembrane import") +AnnotationAssertion( "amino acid import into cell") +AnnotationAssertion( "L-amino acid uptake") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0089718") +AnnotationAssertion(rdfs:label "amino acid import across plasma membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (hypoblast development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:sdb_2009") Annotation( "GOC:tb") "The process whose specific outcome is the progression of the hypoblast over time, from its formation to the mature structure. The hypoblast is a tissue formed from the inner cell mass that lies beneath the epiblast.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2009-07-29T10:25:54Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0090008") +AnnotationAssertion(rdfs:label "hypoblast development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (primitive streak formation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:sdb_2009") Annotation( "GOC:tb") "The developmental process pertaining to the initial formation of the primitive streak from unspecified parts. The primitive streak is a ridge of cells running along the midline of the embryo where the mesoderm ingresses. It defines the anterior-posterior axis.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2009-07-29T10:31:31Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0090009") +AnnotationAssertion(rdfs:label "primitive streak formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (regulation of neutrophil chemotaxis) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the frequency, rate, or extent of neutrophil chemotaxis. Neutrophil chemotaxis is the directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2009-08-03T10:09:34Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0090022") +AnnotationAssertion(rdfs:label "regulation of neutrophil chemotaxis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (positive regulation of neutrophil chemotaxis) AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that increases the frequency, rate, or extent of neutrophil chemotaxis. Neutrophil chemotaxis is the directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding.") @@ -40525,6 +109617,949 @@ AnnotationAssertion( AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0090023") AnnotationAssertion(rdfs:label "positive regulation of neutrophil chemotaxis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of neutrophil chemotaxis) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that decreases the frequency, rate, or extent of neutrophil chemotaxis. Neutrophil chemotaxis is the directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2009-08-03T10:13:09Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0090024") +AnnotationAssertion(rdfs:label "negative regulation of neutrophil chemotaxis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of monocyte chemotaxis) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the frequency, rate, or extent of monocyte chemotaxis.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2009-08-03T10:17:03Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0090025") +AnnotationAssertion(rdfs:label "regulation of monocyte chemotaxis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of monocyte chemotaxis) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that increases the frequency, rate, or extent of monocyte chemotaxis.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2009-08-03T10:18:54Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0090026") +AnnotationAssertion(rdfs:label "positive regulation of monocyte chemotaxis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of monocyte chemotaxis) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that decreases the frequency, rate, or extent of monocyte chemotaxis.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2009-08-03T10:19:40Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0090027") +AnnotationAssertion(rdfs:label "negative regulation of monocyte chemotaxis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of steroid hormone biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroid hormones,compounds with a 1, 2, cyclopentanoperhydrophenanthrene nucleus that act as hormones.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2009-08-03T10:38:27Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0090030") +AnnotationAssertion(rdfs:label "regulation of steroid hormone biosynthetic process") +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of steroid hormone biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroid hormones,compounds with a 1, 2, cyclopentanoperhydrophenanthrene nucleus that act as hormones.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2009-08-03T10:40:32Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0090031") +AnnotationAssertion(rdfs:label "positive regulation of steroid hormone biosynthetic process") +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of steroid hormone biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroid hormones,compounds with a 1, 2, cyclopentanoperhydrophenanthrene nucleus that act as hormones.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2009-08-03T10:41:35Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0090032") +AnnotationAssertion(rdfs:label "negative regulation of steroid hormone biosynthetic process") +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of microtubule nucleation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that increases the rate, frequency or extent of microtubule nucleation. Microtubule nucleation is the 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2009-08-12T11:33:09Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0090063") +AnnotationAssertion(rdfs:label "positive regulation of microtubule nucleation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (positive regulation of cell cycle process) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that increases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2009-09-09T11:39:52Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0090068") +AnnotationAssertion(rdfs:label "positive regulation of cell cycle process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of ribosome biogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis is the cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2009-09-11T10:32:17Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0090069") +AnnotationAssertion(rdfs:label "regulation of ribosome biogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of ribosome biogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that increases the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis is the cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2009-09-11T10:32:17Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0090070") +AnnotationAssertion(rdfs:label "positive regulation of ribosome biogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of ribosome biogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that decreases the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis is the cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2009-09-11T10:32:17Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0090071") +AnnotationAssertion(rdfs:label "negative regulation of ribosome biogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of peptide transport) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the frequency, rate or extent of the directed movement of peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2009-10-23T11:21:38Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0090087") +AnnotationAssertion(rdfs:label "regulation of peptide transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (positive regulation of extracellular matrix disassembly) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that increases the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2009-11-04T10:03:25Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0090091") +AnnotationAssertion(rdfs:label "positive regulation of extracellular matrix disassembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (cochlea development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "The progression of the cochlea over time from its formation to the mature structure. The cochlea is the snail-shaped portion of the inner ear that is responsible for the detection of sound.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2009-11-18T11:42:15Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0090102") +AnnotationAssertion(rdfs:label "cochlea development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cochlea morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "The process in which the cochlea is generated and organized.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2009-11-18T11:45:11Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0090103") +AnnotationAssertion(rdfs:label "cochlea morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (tissue migration) + +AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "The process in which the population of cells that make up a tissue undergo directed movement.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2009-12-07T03:13:55Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0090130") +AnnotationAssertion(rdfs:label "tissue migration") +SubClassOf( ) + +# Class: (mesenchyme migration) + +AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "The process in which the population of cells that make up a mesenchyme undergo directed movement.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2009-12-07T03:15:17Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0090131") +AnnotationAssertion(rdfs:label "mesenchyme migration") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (epithelium migration) + +AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "The process in which the population of cells that make up an epithelium undergo directed movement.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2009-12-07T03:19:34Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0090132") +AnnotationAssertion(rdfs:label "epithelium migration") +SubClassOf( ) + +# Class: (regulation of actin cytoskeleton organization by cell-cell adhesion) + +AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any cell-cell adhesion process that modulates the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2009-12-08T02:05:00Z") +AnnotationAssertion(Annotation( "GOC:mah") "regulation of actin cytoskeleton organisation by cell-cell adhesion") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0090138") +AnnotationAssertion(rdfs:label "regulation of actin cytoskeleton organization by cell-cell adhesion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (establishment of protein localization to membrane) + +AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "The directed movement of a protein to a specific location in a membrane.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2009-12-08T03:18:51Z") +AnnotationAssertion(Annotation( "GOC:mah") "establishment of protein localisation in membrane") +AnnotationAssertion( "establishment of protein localization in membrane") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0090150") +AnnotationAssertion(rdfs:label "establishment of protein localization to membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of sphingolipid biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the rate, frequency or extent of sphingolipid biosynthesis. Sphingolipid biosynthesis is the chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).") +AnnotationAssertion( "tb") +AnnotationAssertion( "2009-12-08T03:25:49Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0090153") +AnnotationAssertion(rdfs:label "regulation of sphingolipid biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of sphingolipid biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that increases the rate, frequency or extent of sphingolipid biosynthesis. Sphingolipid biosynthesis is the chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).") +AnnotationAssertion( "tb") +AnnotationAssertion( "2009-12-08T03:27:33Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0090154") +AnnotationAssertion(rdfs:label "positive regulation of sphingolipid biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of sphingolipid biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that decreases the rate, frequency or extent of sphingolipid biosynthesis. Sphingolipid biosynthesis is the chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).") +AnnotationAssertion( "tb") +AnnotationAssertion( "2009-12-08T03:33:39Z") +AnnotationAssertion( "GO:0090157") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "negative regulation of sphingolipid biosynthesis involved in cellular sphingolipid homeostasis") +AnnotationAssertion( "GO:0090155") +AnnotationAssertion(rdfs:label "negative regulation of sphingolipid biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (intracellular sphingolipid homeostasis) + +AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "A homeostatic process involved in the maintenance of a steady state level of sphingolipids within a cell.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2009-12-08T08:21:36Z") +AnnotationAssertion( "cellular sphingolipid homeostasis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0090156") +AnnotationAssertion(rdfs:label "intracellular sphingolipid homeostasis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (Golgi to lysosome transport) + +AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "The directed movement of substances from the Golgi to lysosomes.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2009-12-08T08:35:13Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0090160") +AnnotationAssertion(rdfs:label "Golgi to lysosome transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (establishment of epithelial cell polarity) + +AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "The specification and formation of anisotropic intracellular organization of an epithelial cell.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2009-12-08T08:58:27Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0090162") +AnnotationAssertion(rdfs:label "establishment of epithelial cell polarity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (Golgi disassembly) + +AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "A cellular process that results in the breakdown of a Golgi apparatus that contributes to Golgi inheritance.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2009-12-08T09:15:11Z") +AnnotationAssertion( "Golgi apparatus disassembly") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0090166") +AnnotationAssertion(rdfs:label "Golgi disassembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (Golgi reassembly) + +AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "The reformation of the Golgi following its breakdown and partitioning contributing to Golgi inheritance.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2009-12-08T09:15:11Z") +AnnotationAssertion( "Golgi apparatus reassembly") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0090168") +AnnotationAssertion(rdfs:label "Golgi reassembly") +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (regulation of Golgi inheritance) + +AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the rate, frequency or extent of Golgi inheritance. Golgi inheritance is the partitioning of Golgi apparatus between daughter cells at cell division.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2009-12-11T10:21:59Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0090170") +AnnotationAssertion(rdfs:label "regulation of Golgi inheritance") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (chondrocyte morphogenesis) + +AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "The process in which the structures of a chondrocyte are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a chondrocyte.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2009-12-11T10:36:02Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0090171") +AnnotationAssertion(rdfs:label "chondrocyte morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (organelle membrane fusion) + +AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "The joining of two lipid bilayers to form a single organelle membrane.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2009-12-11T11:44:58Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0090174") +AnnotationAssertion(rdfs:label "organelle membrane fusion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of kidney development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") Annotation( "GOC:yaf") "Any process that modulates the rate, frequency or extent of kidney development. Kidney development is the process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2009-12-18T10:50:56Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "regulation of nephrogenesis") +AnnotationAssertion( "GO:0090183") +AnnotationAssertion(rdfs:label "regulation of kidney development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of kidney development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") Annotation( "GOC:yaf") "Any process that increases the rate, frequency or extent of kidney development. Kidney development is the process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2009-12-18T10:52:01Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "positive regulation of nephrogenesis") +AnnotationAssertion( "GO:0090184") +AnnotationAssertion(rdfs:label "positive regulation of kidney development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (negative regulation of kidney development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") Annotation( "GOC:yaf") "Any process that decreases the rate, frequency or extent of kidney development. Kidney development is the process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2009-12-18T10:58:45Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "negative regulation of nephrogenesis") +AnnotationAssertion( "GO:0090185") +AnnotationAssertion(rdfs:label "negative regulation of kidney development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of branching involved in ureteric bud morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") Annotation( "GOC:yaf") "Any process that modulates the rate, frequency or extent of branching involved in ureteric bud morphogenesis, the process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2009-12-18T11:11:17Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0090189") +AnnotationAssertion(rdfs:label "regulation of branching involved in ureteric bud morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of branching involved in ureteric bud morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") Annotation( "GOC:yaf") "Any process that increases the rate, frequency or extent of branching involved in ureteric bud morphogenesis, the process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2009-12-18T11:11:17Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0090190") +AnnotationAssertion(rdfs:label "positive regulation of branching involved in ureteric bud morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of branching involved in ureteric bud morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") Annotation( "GOC:yaf") "Any process that decreases the rate, frequency or extent of branching involved in ureteric bud morphogenesis, the process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2009-12-18T11:11:17Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0090191") +AnnotationAssertion(rdfs:label "negative regulation of branching involved in ureteric bud morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of glomerulus development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") Annotation( "GOC:yaf") "Any process that modulates the rate, frequency or extent of glomerulus development, the progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2009-12-18T11:17:13Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0090192") +AnnotationAssertion(rdfs:label "regulation of glomerulus development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (positive regulation of glomerulus development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") Annotation( "GOC:yaf") "Any process that increases the rate, frequency or extent of glomerulus development, the progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2009-12-18T11:17:13Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0090193") +AnnotationAssertion(rdfs:label "positive regulation of glomerulus development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (negative regulation of glomerulus development) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") Annotation( "GOC:yaf") "Any process that decreases the rate, frequency or extent of glomerulus development, the progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2009-12-18T11:17:13Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0090194") +AnnotationAssertion(rdfs:label "negative regulation of glomerulus development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (spongiotrophoblast layer developmental growth) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "The increase in size or mass of the spongiotrophoblast layer of the placenta where the increase in size or mass contributes to the progression of that layer over time from its formation to its mature state.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2010-01-08T12:10:44Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0090214") +AnnotationAssertion(rdfs:label "spongiotrophoblast layer developmental growth") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (epithelium migration involved in imaginal disc-derived wing morphogenesis) + +AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "The process in which the population of cells that make up a wing epithelium undergo directed movement and contribute to imaginal disc-derived morphogenesis.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2010-01-22T11:40:46Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0090252") +AnnotationAssertion(rdfs:label "epithelium migration involved in imaginal disc-derived wing morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (cell proliferation involved in imaginal disc-derived wing morphogenesis) + +AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to imaginal disc-derived wing morphogenesis.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2010-01-22T11:40:46Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0090255") +AnnotationAssertion(rdfs:label "cell proliferation involved in imaginal disc-derived wing morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of cell proliferation involved in imaginal disc-derived wing morphogenesis) + +AnnotationAssertion(Annotation( "GOC:ascb_2009") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the frequency, rate, or extent of the multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to imaginal disc-derived wing morphogenesis.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2010-01-22T11:40:46Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0090256") +AnnotationAssertion(rdfs:label "regulation of cell proliferation involved in imaginal disc-derived wing morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (regulation of muscle system process) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the frequency, rate or extent of a muscle system process, a multicellular organismal process carried out by any of the organs or tissues in a muscle system.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2010-02-03T11:48:13Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0090257") +AnnotationAssertion(rdfs:label "regulation of muscle system process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of somatostatin secretion) + +AnnotationAssertion(Annotation( "GOC:BHF") "Any process that modulates the rate, frequency, extent of the regulated release of somatostatin from secretory granules in the D cells of the pancreas.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2010-02-05T02:54:14Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0090273") +AnnotationAssertion(rdfs:label "regulation of somatostatin secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (positive regulation of somatostatin secretion) + +AnnotationAssertion(Annotation( "GOC:BHF") "Any process that increases the rate, frequency, extent of the regulated release of somatostatin from secretory granules in the D cells of the pancreas.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2010-02-05T02:54:14Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0090274") +AnnotationAssertion(rdfs:label "positive regulation of somatostatin secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of somatostatin secretion) + +AnnotationAssertion(Annotation( "GOC:BHF") "Any process that decreases the rate, frequency, extent of the regulated release of somatostatin from secretory granules in the D cells of the pancreas.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2010-02-05T02:54:14Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0090275") +AnnotationAssertion(rdfs:label "negative regulation of somatostatin secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of peptide hormone secretion) + +AnnotationAssertion(Annotation( "GOC:tb") "Any process that modulates the rate, frequency, or extent of the regulated release of a peptide hormone from secretory granules.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2010-02-05T02:56:39Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0090276") +AnnotationAssertion(rdfs:label "regulation of peptide hormone secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of peptide hormone secretion) + +AnnotationAssertion(Annotation( "GOC:tb") "Any process that increases the rate, frequency, or extent of the regulated release of a peptide hormone from secretory granules.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2010-02-05T02:56:39Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0090277") +AnnotationAssertion(rdfs:label "positive regulation of peptide hormone secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of peptide hormone secretion) + +AnnotationAssertion(Annotation( "GOC:tb") "Any process that decreases the rate, frequency, or extent of the regulated release of a peptide hormone from secretory granules.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2010-02-05T02:56:39Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0090278") +AnnotationAssertion(rdfs:label "negative regulation of peptide hormone secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of osteoclast proliferation) + +AnnotationAssertion(Annotation( "GOC:tb") "Any process that modulates the rate, frequency, or extent of the multiplication or reproduction of osteoclasts, resulting in the expansion of an osteoclast cell population.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2010-02-18T03:11:03Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0090289") +AnnotationAssertion(rdfs:label "regulation of osteoclast proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of osteoclast proliferation) + +AnnotationAssertion(Annotation( "GOC:tb") "Any process that increases the rate, frequency, or extent of the multiplication or reproduction of osteoclasts, resulting in the expansion of an osteoclast cell population.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2010-02-18T03:11:03Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0090290") +AnnotationAssertion(rdfs:label "positive regulation of osteoclast proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of osteoclast proliferation) + +AnnotationAssertion(Annotation( "GOC:tb") "Any process that decreases the rate, frequency, or extent of the multiplication or reproduction of osteoclasts, resulting in the expansion of an osteoclast cell population.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2010-02-18T03:11:03Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0090291") +AnnotationAssertion(rdfs:label "negative regulation of osteoclast proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of neural crest formation) + +AnnotationAssertion(Annotation( "GOC:tb") "Any process that modulates the rate, frequency, or extent of neural crest formation. Neural crest formation is the formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation proceeds.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2010-03-12T04:08:26Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0090299") +AnnotationAssertion(rdfs:label "regulation of neural crest formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (positive regulation of neural crest formation) + +AnnotationAssertion(Annotation( "GOC:tb") "Any process that increases the rate, frequency, or extent of neural crest formation. Neural crest formation is the formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation procedes.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2010-03-12T04:08:26Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0090300") +AnnotationAssertion(rdfs:label "positive regulation of neural crest formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of neural crest formation) + +AnnotationAssertion(Annotation( "GOC:tb") "Any process that decreases the rate, frequency, or extent of neural crest formation. Neural crest formation is the formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation procedes.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2010-03-12T04:08:26Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0090301") +AnnotationAssertion(rdfs:label "negative regulation of neural crest formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of wound healing) + +AnnotationAssertion(Annotation( "GOC:BHF") "Any process that increases the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2010-03-22T02:12:03Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0090303") +AnnotationAssertion(rdfs:label "positive regulation of wound healing") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (nucleic acid metabolic process) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any cellular metabolic process involving nucleic acids.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2010-04-07T10:18:47Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0090304") +AnnotationAssertion(rdfs:label "nucleic acid metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of intracellular protein transport) + +AnnotationAssertion(Annotation( "GOC:tb") "Any process that activates or increases the frequency, rate or extent of the directed movement of proteins within cells.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2010-04-16T03:45:07Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0090316") +AnnotationAssertion(rdfs:label "positive regulation of intracellular protein transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of intracellular protein transport) + +AnnotationAssertion(Annotation( "GOC:tb") "Any process that decreases the frequency, rate or extent of the directed movement of proteins within cells.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2010-04-16T03:45:07Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0090317") +AnnotationAssertion(rdfs:label "negative regulation of intracellular protein transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (regulation of locomotion involved in locomotory behavior) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:kmv") Annotation( "GOC:tb") "Any process that modulates the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2010-05-14T10:24:29Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0090325") +AnnotationAssertion(rdfs:label "regulation of locomotion involved in locomotory behavior") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of locomotion involved in locomotory behavior) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:kmv") Annotation( "GOC:tb") "Any process that increases the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2010-05-14T10:26:58Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0090326") +AnnotationAssertion(rdfs:label "positive regulation of locomotion involved in locomotory behavior") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of locomotion involved in locomotory behavior) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:kmv") Annotation( "GOC:tb") "Any process that decreases the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2010-05-14T10:26:58Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0090327") +AnnotationAssertion(rdfs:label "negative regulation of locomotion involved in locomotory behavior") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of olfactory learning) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the rate, frequency, or extent of olfactory learning. Olfactory learning is any process in an organism in which a relatively long-lasting adaptive behavioral change occurs in response to (repeated) exposure to an olfactory cue.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2010-05-14T10:37:22Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0090328") +AnnotationAssertion(rdfs:label "regulation of olfactory learning") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of brown fat cell differentiation) + +AnnotationAssertion(Annotation( "GOC:tb") "Any process that modulates the rate, frequency, or extent of brown fat cell differentiation. Brown fat cell differentiation is the process in which a relatively unspecialized cell acquires specialized features of a brown adipocyte, an animal connective tissue cell involved in adaptive thermogenesis. Brown adipocytes contain multiple small droplets of triglycerides and a high number of mitochondria.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2010-06-01T03:16:57Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0090335") +AnnotationAssertion(rdfs:label "regulation of brown fat cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of brown fat cell differentiation) + +AnnotationAssertion(Annotation( "GOC:BHF") "Any process that increases the rate, frequency, or extent of brown fat cell differentiation. Brown fat cell differentiation is the process in which a relatively unspecialized cell acquires specialized features of a brown adipocyte, an animal connective tissue cell involved in adaptive thermogenesis. Brown adipocytes contain multiple small droplets of triglycerides and a high number of mitochondria.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2010-06-01T03:19:26Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0090336") +AnnotationAssertion(rdfs:label "positive regulation of brown fat cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of excitatory postsynaptic potential) + +AnnotationAssertion(Annotation( "GOC:BHF") "Any process that prevents the establishment or decreases the extent of the excitatory postsynaptic potential (EPSP) which is a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2010-12-15T01:43:12Z") +AnnotationAssertion( "negative regulation of excitatory post-synaptic membrane potential") +AnnotationAssertion(Annotation( "GOC:bf") "reduction of excitatory postsynaptic membrane potential") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "negative regulation of EPSP") +AnnotationAssertion( "GO:0090394") +AnnotationAssertion(rdfs:label "negative regulation of excitatory postsynaptic potential") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (organophosphate biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:chem_mtg") "The chemical reactions and pathways resulting in the biosynthesis of deoxyribose phosphate, the phosphorylated sugar 2-deoxy-erythro-pentose.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2011-02-26T02:22:41Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0090407") +AnnotationAssertion(rdfs:label "organophosphate biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (acinar cell differentiation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "The epithelial cell differentiation process in which a relatively unspecialized cell acquires specialized features of an acinar cell, a secretory cell that is grouped together with other cells of the same type to form grape-shaped clusters known as acini.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2012-05-04T09:24:48Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0090425") +AnnotationAssertion(rdfs:label "acinar cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (protein localization to nuclear envelope) + +AnnotationAssertion(Annotation( "GOC:tb") "A process in which a protein is transported to, or maintained at, a location within a nuclear envelope.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2012-07-30T01:50:41Z") +AnnotationAssertion( "protein localization in nuclear envelope") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0090435") +AnnotationAssertion(rdfs:label "protein localization to nuclear envelope") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (glutamate transmembrane import into vacuole) + +AnnotationAssertion(Annotation( "GOC:tb") "The directed movement of glutamate into the vacuole across the vacuolar membrane.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2012-09-24T14:12:46Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:tb") "vacuolar glutamate import") +AnnotationAssertion( "GO:0090454") +AnnotationAssertion(rdfs:label "glutamate transmembrane import into vacuole") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (intracellular glutamate homeostasis) + +AnnotationAssertion(Annotation( "GOC:tb") "A homeostatic process involved in the maintenance of a steady state level of glutamate within a cell.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/24220"^^xsd:anyURI) +AnnotationAssertion( "tb") +AnnotationAssertion( "2012-09-24T14:22:02Z") +AnnotationAssertion( "cellular glutamate homeostasis") +AnnotationAssertion( "glutamate homeostasis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0090461") +AnnotationAssertion(rdfs:label "intracellular glutamate homeostasis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (catecholamine uptake) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "The directed movement of catecholamine into a cell.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2012-10-17T11:06:17Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0090493") +AnnotationAssertion(rdfs:label "catecholamine uptake") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (dopamine uptake) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "The directed movement of dopamine into a cell.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2012-10-17T11:12:09Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0090494") +AnnotationAssertion(rdfs:label "dopamine uptake") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (mesenchyme migration involved in limb bud formation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "The migration of mesenchymal tissue that contributes to the formation of a limb bud.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2012-10-17T12:04:20Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0090496") +AnnotationAssertion(rdfs:label "mesenchyme migration involved in limb bud formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (mesenchymal cell migration) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "The orderly movement of a mesenchymal cell from one site to another, often during the development of a multicellular organism.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2012-10-17T12:08:17Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0090497") +AnnotationAssertion(rdfs:label "mesenchymal cell migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (L-glutamate transmembrane import into vacuole) + +AnnotationAssertion(Annotation( "GOC:al") "The directed movement of L-glutamate into the vacuole across the vacuolar membrane.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2012-12-14T11:25:52Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0090515") +AnnotationAssertion(rdfs:label "L-glutamate transmembrane import into vacuole") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (podocyte cell migration) + +AnnotationAssertion(Annotation( "GOC:pm") Annotation( "PMID:21402783") "The orderly movement of a podocyte from one site to another, often during the development of a multicellular organism or multicellular structure. A podocyte is a specialized kidney epithelial cell.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/23000"^^xsd:anyURI) +AnnotationAssertion( "tb") +AnnotationAssertion( "2013-01-08T11:08:57Z") +AnnotationAssertion( "glomerular visceral epithelial cell migration") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0090521") +AnnotationAssertion(rdfs:label "podocyte cell migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (inflammatory response to wounding) + +AnnotationAssertion(Annotation( "GOC:add") "The immediate defensive reaction by vertebrate tissue to injury caused by chemical or physical agents.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2014-08-12T12:13:53Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0090594") +AnnotationAssertion(rdfs:label "inflammatory response to wounding") +SubClassOf( ) +SubClassOf( ) + +# Class: (sensory organ morphogenesis) + +AnnotationAssertion(Annotation( "GOC:kmv") Annotation( "ISBN:978-0199210893") "Morphogenesis of a sensory organ. A sensory organ is defined as a tissue or set of tissues that work together to receive and transmit signals from external or internal stimuli. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2014-08-22T13:23:20Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0090596") +AnnotationAssertion(rdfs:label "sensory organ morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (male anatomical structure morphogenesis) + +AnnotationAssertion(Annotation( "GOC:kmv") Annotation( "GOC:tb") "The processes by which anatomical structures that are only present in the male organism are generated and organized.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2014-08-22T13:29:45Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0090598") +AnnotationAssertion(rdfs:label "male anatomical structure morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (RNA localization to nucleus) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "PMID:26305931") "A macromolecular localization process in which RNA is transported to and maintained in a location within the nucleus.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2016-07-19T17:00:49Z") +AnnotationAssertion(Annotation( "GOC:mah") "RNA localisation to nucleus") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0090685") +AnnotationAssertion(rdfs:label "RNA localization to nucleus") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) # Class: (immunological memory process) @@ -40547,6 +110582,267 @@ AnnotationAssertion( "immunological memory formation process") SubClassOf( ) +# Class: (pigment granule membrane) + +AnnotationAssertion(Annotation( "PMID:11294610") "Any membrane that is part of a pigment granule.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2017-05-16T22:33:39Z") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0090741") +AnnotationAssertion(rdfs:label "pigment granule membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (acetylcholine receptor signaling pathway) + +AnnotationAssertion(Annotation( "GOC:mah") "The series of molecular signals generated as a consequence of an acetylcholine receptor binding to one of its physiological ligands.") +AnnotationAssertion( "acetylcholine receptor signalling pathway") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0095500") +AnnotationAssertion(rdfs:label "acetylcholine receptor signaling pathway") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (ceramide binding) + +AnnotationAssertion(Annotation( "GOC:sart") "Binding to a ceramide, a class of lipids composed of sphingosine linked to a fatty acid. Ceramides are a major component of cell membranes.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2011-03-09T11:34:09Z") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0097001") +AnnotationAssertion(rdfs:label "ceramide binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (ciliary plasm) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:cilia") Annotation( "GOC:dos") Annotation( "PMID:17895364") "All of the contents of a cilium, excluding the plasma membrane surrounding the cilium.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2011-03-23T01:52:31Z") +AnnotationAssertion( "cilium plasm") +AnnotationAssertion( "microtubule-based flagellar matrix") +AnnotationAssertion( "microtubule-based flagellum matrix") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "cilial cytoplasm") +AnnotationAssertion( "ciliary cytoplasm") +AnnotationAssertion( "cilium cytoplasm") +AnnotationAssertion( "microtubule-based flagellar cytoplasm") +AnnotationAssertion( "microtubule-based flagellum cytoplasm") +AnnotationAssertion( "GO:0097014") +AnnotationAssertion(rdfs:comment "Note that we deem cilium and microtubule-based flagellum to be equivalent. Also, researchers consider the composition of both the plasm and the membrane of the cilium to be detectably different from that in the non-ciliary cytosol and plasma membrane (e.g. in terms of calcium ion concentration, membrane lipid composition, and more). For this reason, the term \"ciliary plasm\" is not linked to \"cytoplasm\".") +AnnotationAssertion(rdfs:label "ciliary plasm") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (dendritic cell dendrite assembly) + +AnnotationAssertion(Annotation( "CL:0000451") Annotation( "GOC:BHF") Annotation( "PMID:12200351") "Formation of dendrites, branched cellular projections (or cytoplasmic extension) that are extended from the surface of a dendritic immune cell, and which enable the cell to sample luminal pathogens and increase the surface area for antigen presentation to T cells.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2011-03-31T04:52:53Z") +AnnotationAssertion( "dendritic extension") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0097026") +AnnotationAssertion(rdfs:comment "Note that dendrites of dendritic cells should not be confused with neuronal cell dendrites, which process electrical signals.") +AnnotationAssertion(rdfs:label "dendritic cell dendrite assembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (dendritic cell differentiation) + +AnnotationAssertion(Annotation( "CL:0000451") Annotation( "GOC:pr") "The process in which a precursor cell type acquires the specialized features of a dendritic cell. A dendritic cell is a leukocyte of dendritic lineage specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2011-04-01T10:08:42Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0097028") +AnnotationAssertion(rdfs:comment "Note that immunologists typically use the word 'maturation' to refer to dendritic cells undergoing the process that GO describes as 'cell differentiation'.") +AnnotationAssertion(rdfs:label "dendritic cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (dendritic cell apoptotic process) + +AnnotationAssertion(Annotation( "CL:0000451") Annotation( "GOC:BHF") Annotation( "GOC:mtg_apoptosis") Annotation( "PMID:15059845") "Any apoptotic process in a dendritic cell, a cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2011-05-04T02:18:59Z") +AnnotationAssertion( "dendritic cell apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0097048") +AnnotationAssertion(rdfs:label "dendritic cell apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (motor neuron apoptotic process) + +AnnotationAssertion(Annotation( "CL:0000100") Annotation( "GOC:BHF") Annotation( "GOC:mtg_apoptosis") Annotation( "PMID:14523086") "Any apoptotic process in a motor neuron, an efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes movement.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2011-05-04T02:21:43Z") +AnnotationAssertion( "motoneuron apoptosis") +AnnotationAssertion( "motor neuron apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0097049") +AnnotationAssertion(rdfs:label "motor neuron apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (type B pancreatic cell apoptotic process) + +AnnotationAssertion(Annotation( "CL:0000169") Annotation( "GOC:BHF") Annotation( "GOC:mtg_apoptosis") Annotation( "PMID:16087305") "Any apoptotic process in a type B pancreatic cell, a cell located towards center of the islets of Langerhans that secretes insulin.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2011-05-04T02:24:38Z") +AnnotationAssertion( "pancreatic B cell apoptosis") +AnnotationAssertion( "pancreatic beta cell apoptosis") +AnnotationAssertion( "type B pancreatic cell apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0097050") +AnnotationAssertion(rdfs:label "type B pancreatic cell apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (L-glutamate biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:yaf") "The chemical reactions and pathways resulting in the formation of L-glutamate, the L enantiomer anion of 2-aminopentanedioic acid.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2011-05-24T04:30:38Z") +AnnotationAssertion( "L-glutamate anabolism") +AnnotationAssertion( "L-glutamate biosynthesis") +AnnotationAssertion( "L-glutamate formation") +AnnotationAssertion( "L-glutamate synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0097054") +AnnotationAssertion(rdfs:label "L-glutamate biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (synaptic membrane) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "PMID:20410104") "A specialized area of membrane on either the presynaptic or the postsynaptic side of a synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2011-06-07T11:22:09Z") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0097060") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "synaptic membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (vascular associated smooth muscle cell development) + +AnnotationAssertion(Annotation( "GOC:BHF") "The process aimed at the progression of a vascular smooth muscle cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. A vascular smooth muscle cell is a non-striated, elongated, spindle-shaped cell found lining the blood vessels.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2011-06-20T04:03:08Z") +AnnotationAssertion( "vascular smooth muscle cell development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0097084") +AnnotationAssertion(rdfs:label "vascular associated smooth muscle cell development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (craniofacial suture morphogenesis) + +AnnotationAssertion(Annotation( "GOC:pr") Annotation( "GOC:sl") Annotation( "Wikipedia:Cranial_sutures") Annotation( "Wikipedia:Head_and_neck_anatomy#Musculoskeletal_system") "The process in which any suture between cranial and/or facial bones is generated and organized.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2011-07-05T02:51:54Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0097094") +AnnotationAssertion(rdfs:label "craniofacial suture morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectAllValuesFrom( )) + +# Class: (frontonasal suture morphogenesis) + +AnnotationAssertion(Annotation( "GOC:pr") Annotation( "GOC:sl") Annotation( "PMID:12416537") Annotation( "Wikipedia:Cranial_sutures") Annotation( "Wikipedia:Head_and_neck_anatomy#Musculoskeletal_system") "The process in which the frontonasal suture, between frontal and nasal bones, is generated and organized.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2011-07-05T02:57:46Z") +AnnotationAssertion( "nasofrontal suture morphogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0097095") +AnnotationAssertion(rdfs:label "frontonasal suture morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (facial suture morphogenesis) + +AnnotationAssertion(Annotation( "GOC:pr") Annotation( "GOC:sl") Annotation( "Wikipedia:Cranial_sutures") Annotation( "Wikipedia:Head_and_neck_anatomy#Musculoskeletal_system") "The process in which any suture between facial bones is generated and organized.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2011-07-05T03:06:27Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0097096") +AnnotationAssertion(rdfs:label "facial suture morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (nasal suture morphogenesis) + +AnnotationAssertion(Annotation( "GOC:pr") Annotation( "GOC:sl") Annotation( "Wikipedia:Cranial_sutures") Annotation( "Wikipedia:Head_and_neck_anatomy#Musculoskeletal_system") "The process in which the nasal suture is generated and organized.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2011-07-05T03:09:04Z") +AnnotationAssertion( "internasal suture morphogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0097097") +AnnotationAssertion(rdfs:label "nasal suture morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (postsynaptic membrane assembly) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:sjp") Annotation( "PMID:21424692") "The aggregation, arrangement and bonding together of a set of components to form a postsynaptic membrane, a specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft).") +AnnotationAssertion( "pr") +AnnotationAssertion( "2011-07-27T01:26:49Z") +AnnotationAssertion( "post-synaptic membrane assembly") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0097104") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "postsynaptic membrane assembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (receptor localization to synapse) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:sjp") Annotation( "PMID:21525273") "Any process in which a receptor is transported to, and/or maintained at the synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2011-07-31T09:20:30Z") +AnnotationAssertion( "receptor localisation to synapse") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0097120") +AnnotationAssertion(rdfs:label "receptor localization to synapse") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (mesenchymal cell apoptotic process) + +AnnotationAssertion(Annotation( "CL:0000134") Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:yaf") Annotation( "PMID:18231833") "Any apoptotic process in a mesenchymal cell. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2011-09-06T02:31:59Z") +AnnotationAssertion( "mesenchymal cell apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0097152") +AnnotationAssertion(rdfs:label "mesenchymal cell apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (GABAergic neuron differentiation) + +AnnotationAssertion(Annotation( "GOC:kmv") Annotation( "PMID:11517269") "The process in which a neuroblast acquires the specialized structural and functional features of a GABAergic neuron.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2011-09-14T09:39:11Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0097154") +AnnotationAssertion(rdfs:label "GABAergic neuron differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (organic cyclic compound binding) + +AnnotationAssertion(Annotation( "GOC:sjw") Annotation( "PMID:7583672") "Binding to an organic cyclic compound, any molecular entity that contains carbon arranged in a cyclic molecular structure.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2011-09-23T02:31:01Z") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0097159") +AnnotationAssertion(rdfs:label "organic cyclic compound binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (ammonium ion metabolic process) AnnotationAssertion(Annotation( "GOC:dhl") Annotation( "GOC:tb") Annotation( "PMID:14671018") "The chemical reactions and pathways involving the ammonium ion.") @@ -40557,6 +110853,7 @@ AnnotationAssertion( "ammonium metabolic process") AnnotationAssertion( "GO:0097164") AnnotationAssertion(rdfs:label "ammonium ion metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) # Class: (amelogenesis) @@ -40568,8 +110865,51 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0097186") AnnotationAssertion(rdfs:label "amelogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (dentinogenesis) + +AnnotationAssertion(Annotation( "GOC:cjm") Annotation( "GOC:sl") Annotation( "PMID:10206335") Annotation( "PMID:21196346") "The process whose specific outcome is the formation of dentin, the mineralized tissue that constitutes the major bulk of teeth. Dentin may be one of three types: primary dentin, secondary dentin, and tertiary dentin.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2011-11-21T09:04:17Z") +AnnotationAssertion( "dentin development") +AnnotationAssertion( "dentine development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0097187") +AnnotationAssertion(rdfs:label "dentinogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (apoptotic signaling pathway) + +AnnotationAssertion(Annotation( "GOC:mtg_apoptosis") "The series of molecular signals which triggers the apoptotic death of a cell. The pathway starts with reception of a signal, and ends when the execution phase of apoptosis is triggered.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2011-11-23T09:30:23Z") +AnnotationAssertion( "GO:0008624") +AnnotationAssertion(Annotation( "GOC:mah") "apoptotic signalling pathway") +AnnotationAssertion( "induction of apoptosis by extracellular signals") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0097190") +AnnotationAssertion(rdfs:comment "This term can be used to annotate gene products involved in apoptotic events happening downstream of the cross-talk point between the extrinsic and intrinsic apoptotic pathways. The cross-talk starts when caspase-8 cleaves Bid and truncated Bid interacts with mitochondria. From this point on it is not possible to distinguish between extrinsic and intrinsic pathways.") +AnnotationAssertion(rdfs:label "apoptotic signaling pathway") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (execution phase of apoptosis) + +AnnotationAssertion(Annotation( "GOC:mtg_apoptosis") Annotation( "PMID:21760595") "A stage of the apoptotic process that starts with the controlled breakdown of the cell through the action of effector caspases or other effector molecules (e.g. cathepsins, calpains etc.). Key steps of the execution phase are rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2011-11-23T09:45:24Z") +AnnotationAssertion( "execution phase of apoptotic process") +AnnotationAssertion( "apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0097194") +AnnotationAssertion(rdfs:label "execution phase of apoptosis") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (renal filtration) AnnotationAssertion(Annotation( "GOC:pr") Annotation( "GOC:sart") "A renal system process in which fluid circulating through the body is filtered through a barrier system.") @@ -40580,6 +110920,41 @@ AnnotationAssertion( "renal filtration") SubClassOf( ) +# Class: (lysosomal membrane organization) + +AnnotationAssertion(Annotation( "GOC:yaf") Annotation( "PMID:20544854") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lysosomal membrane. A lysosomal membrane is the lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2012-01-12T10:16:15Z") +AnnotationAssertion(Annotation( "GOC:mah") "lysosomal membrane organisation") +AnnotationAssertion( "lysosome membrane organization") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0097212") +AnnotationAssertion(rdfs:label "lysosomal membrane organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cellular response to toxic substance) + +AnnotationAssertion(Annotation( "GOC:pr") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toxic stimulus.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2012-02-02T12:23:31Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0097237") +AnnotationAssertion(rdfs:label "cellular response to toxic substance") + +# Class: (oligodendrocyte apoptotic process) + +AnnotationAssertion(Annotation( "CL:0000128") Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:yaf") Annotation( "PMID:16723520") "Any apoptotic process in an oligodendrocyte. Oligodendrocytes belong to a class of large neuroglial (macroglial) cells in the central nervous system, where they form the insulating myelin sheath of axons.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2012-03-05T10:51:15Z") +AnnotationAssertion( "oligodendrocyte apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0097252") +AnnotationAssertion(rdfs:label "oligodendrocyte apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + # Class: (renal tubular secretion) AnnotationAssertion(Annotation( "GOC:rph") Annotation( "PMID:25287933") Annotation( "Wikipedia:Renal_secretion#Secretion") "The elimination of substances from peritubular capillaries (or surrounding hemolymph in invertebrates) into the renal tubules to be incorporated subsequently into the urine. Substances that are secreted include organic anions, ammonia, potassium and drugs.") @@ -40592,6 +110967,124 @@ AnnotationAssertion(rdfs:label "rena SubClassOf( ) SubClassOf( ) +# Class: (ammonium homeostasis) + +AnnotationAssertion(Annotation( "GOC:yaf") Annotation( "PMID:12695560") "Any biological process involved in the maintenance of an internal steady state of ammonium.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2012-03-22T02:51:22Z") +AnnotationAssertion( "ammonia homeostasis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0097272") +AnnotationAssertion(rdfs:label "ammonium homeostasis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (intracellular ammonium homeostasis) + +AnnotationAssertion(Annotation( "GOC:yaf") Annotation( "PMID:12695560") "A homeostatic process involved in the maintenance of a steady state level of ammonium within a cell.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2012-03-22T02:54:38Z") +AnnotationAssertion( "cellular ammonia homeostasis") +AnnotationAssertion( "cellular ammonium homeostasis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0097275") +AnnotationAssertion(rdfs:label "intracellular ammonium homeostasis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (keratinocyte apoptotic process) + +AnnotationAssertion(Annotation( "CL:0000312") Annotation( "GOC:jc") Annotation( "GOC:mtg_apoptosis") Annotation( "PMID:10201527") "Any apoptotic process in a keratinocyte. A keratinocyte is an epidermal cell which synthesizes keratin and undergoes a characteristic change as it moves upward from the basal layers of the epidermis to the cornified (horny) layer of the skin.") +AnnotationAssertion( ) +AnnotationAssertion( "pr") +AnnotationAssertion( "2012-03-29T10:20:51Z") +AnnotationAssertion( "keratinocyte apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0097283") +AnnotationAssertion(rdfs:label "keratinocyte apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses( ObjectSomeValuesFrom( )) + +# Class: (hepatocyte apoptotic process) + +AnnotationAssertion(Annotation( "CL:0000182") Annotation( "GOC:jc") Annotation( "GOC:mtg_apoptosis") Annotation( "PMID:15856020") "Any apoptotic process in a hepatocyte, the main structural component of the liver.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2012-03-29T10:23:21Z") +AnnotationAssertion( "hepatocyte apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0097284") +AnnotationAssertion(rdfs:label "hepatocyte apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (response to alcohol) + +AnnotationAssertion(Annotation( "GOC:pr") Annotation( "PMID:24014527") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alcohol stimulus.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2012-05-15T03:48:45Z") +AnnotationAssertion( "GO:1990335") +AnnotationAssertion( "process resulting in tolerance to alcohol") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0097305") +AnnotationAssertion(rdfs:label "response to alcohol") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (cellular response to alcohol) + +AnnotationAssertion(Annotation( "GOC:pr") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alcohol stimulus.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2012-05-15T03:49:51Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0097306") +AnnotationAssertion(rdfs:label "cellular response to alcohol") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (melanocyte migration) + +AnnotationAssertion(Annotation( "CL:0000148") Annotation( "GOC:uh") Annotation( "PMID:22637532") "The orderly movement of melanocytes from one site to another, often during the development of a multicellular organism. A melanocyte is a pigment cell derived from the neural crest. It contains melanin-filled pigment granules, which give a brown to black appearance.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2012-06-08T10:08:18Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0097324") +AnnotationAssertion(rdfs:label "melanocyte migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (protein localization to heterochromatin) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process in which a protein is transported to, or maintained at, a part of a chromosome that is organized into heterochromatin.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2012-07-03T03:19:07Z") +AnnotationAssertion(Annotation( "GOC:mah") "protein localisation to heterochromatin") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0097355") +AnnotationAssertion(rdfs:label "protein localization to heterochromatin") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (chorionic trophoblast cell proliferation) + +AnnotationAssertion(Annotation( "CL:0011101") Annotation( "GOC:BHF") Annotation( "PMID:15150278") "The multiplication or reproduction of chorionic trophoblast cells, resulting in the expansion of their population.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2012-07-19T10:17:37Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0097360") +AnnotationAssertion(rdfs:label "chorionic trophoblast cell proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (carbohydrate derivative binding) + +AnnotationAssertion(Annotation( "GOC:pr") "Binding to a carbohydrate derivative.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2012-08-02T13:03:39Z") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0097367") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "carbohydrate derivative binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + # Class: (glial cell projection) AnnotationAssertion(Annotation( "GOC:mc") "A prolongation or process extending from a glial cell.") @@ -40602,6 +111095,72 @@ AnnotationAssertion( "glial projection") AnnotationAssertion( "GO:0097386") AnnotationAssertion(rdfs:label "glial cell projection") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (neuroblast migration) + +AnnotationAssertion(Annotation( "CL:0000031") Annotation( "GOC:jc") Annotation( "PMID:15543145") "The orderly movement of a neuroblast from one site to another, often during the development of a multicellular organism or multicellular structure. A neuroblast is any cell that will divide and give rise to a neuron.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2012-10-29T08:24:37Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0097402") +AnnotationAssertion(rdfs:label "neuroblast migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (hippocampal interneuron differentiation) + +AnnotationAssertion(Annotation( "CL:1001569") Annotation( "GOC:jc") Annotation( "PMID:19655320") "The process in which a relatively unspecialized cell acquires specialized features of a hippocampal interneuron.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2012-11-04T10:58:28Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0097410") +AnnotationAssertion(rdfs:label "hippocampal interneuron differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (microtubule bundle) + +AnnotationAssertion(Annotation( "NIF_Subcellular:sao1872343973") "An arrangement of closely apposed microtubules running parallel to each other.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2012-11-07T15:01:27Z") +AnnotationAssertion( "NIF_Subcellular:sao1872343973") +AnnotationAssertion( "microtubule fascicle") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0097427") +AnnotationAssertion(rdfs:label "microtubule bundle") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (hippocampal pyramidal neuron differentiation) + +AnnotationAssertion(Annotation( "CL:1001571") Annotation( "GOC:jc") Annotation( "PMID:19342486") "The process in which a relatively unspecialized cell acquires specialized features of a hippocampal pyramidal neuron, a pyramidal cell of the hippocampus.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2012-11-22T09:33:31Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0097432") +AnnotationAssertion(rdfs:label "hippocampal pyramidal neuron differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (supramolecular fiber organization) + +AnnotationAssertion(Annotation( "GOC:pr") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a supramolecular fiber, a polymer consisting of an indefinite number of protein or protein complex subunits that have polymerised to form a fiber-shaped structure.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2012-11-27T15:46:25Z") +AnnotationAssertion( "GO:0043206") +AnnotationAssertion( "extracellular fibril organisation") +AnnotationAssertion( "extracellular fibril organization") +AnnotationAssertion(Annotation( "GOC:mah") "extracellular fibril organization and biogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "fibril organisation") +AnnotationAssertion( "fibril organization") +AnnotationAssertion( "GO:0097435") +AnnotationAssertion(rdfs:label "supramolecular fiber organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) # Class: (dendritic tree) @@ -40628,6 +111187,7 @@ AnnotationAssertion(Annotation( "NIF_Subcellular:sao1189060993") "vellous process") AnnotationAssertion( "GO:0097449") AnnotationAssertion(rdfs:label "astrocyte projection") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) # Class: (astrocyte end-foot) @@ -40642,6 +111202,18 @@ AnnotationAssertion( "astrocyte end-foot") SubClassOf( ) +# Class: (Schwann cell microvillus) + +AnnotationAssertion(Annotation( "NIF_Subcellular:sao1890444066") Annotation( "PMID:15988042") "Small finger-like extension of a Schwann cell that contacts the nodal membrane.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2012-12-19T13:01:02Z") +AnnotationAssertion( "NIF_Subcellular:sao1890444066") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0097454") +AnnotationAssertion(rdfs:label "Schwann cell microvillus") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + # Class: (hippocampal mossy fiber) AnnotationAssertion(Annotation( "NIF_Subcellular:nlx_subcell_100312") Annotation( "PMID:17765709") Annotation( "PMID:20554881") Annotation( "PMID:24336151") "An axon of a hippocampal granule cell, including dentate gyrus granule cell and CA3 granule cell, characterized by expansions (mossy fiber expansions) giving the fibers a mossy appearance. These unmyelinated axons were first described by Ramon y Cajal.") @@ -40655,6 +111227,200 @@ AnnotationAssertion(rdfs:label "hipp SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (retinal rod cell apoptotic process) + +AnnotationAssertion(Annotation( "CL:0000604") Annotation( "GOC:jc") Annotation( "PMID:17202487") "Any apoptotic process in a retinal rod cell, one of the two photoreceptor cell types of the vertebrate retina.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2013-03-21T09:44:45Z") +AnnotationAssertion( "rod photoreceptor apoptotic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0097473") +AnnotationAssertion(rdfs:label "retinal rod cell apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (retinal cone cell apoptotic process) + +AnnotationAssertion(Annotation( "CL:0000573") Annotation( "GOC:jc") "Any apoptotic process in a retinal cone cell, one of the two photoreceptor cell types of the vertebrate retina.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2013-03-21T09:46:22Z") +AnnotationAssertion( "cone photoreceptor apoptotic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0097474") +AnnotationAssertion(rdfs:label "retinal cone cell apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (motor neuron migration) + +AnnotationAssertion(Annotation( "CL:0000100") Annotation( "GOC:yaf") Annotation( "PMID:20711475") "The orderly movement of a motor neuron from one site to another. A motor neuron is an efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes movement.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2013-04-23T13:00:46Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0097475") +AnnotationAssertion(rdfs:label "motor neuron migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (spinal cord motor neuron migration) + +AnnotationAssertion(Annotation( "CL:0011001") Annotation( "GOC:yaf") Annotation( "PMID:20711475") "The orderly movement of a spinal cord motor neuron from one site to another. A spinal cord motor neuron is a motor neuron that passes from the spinal cord toward or to a muscle and conducts an impulse that causes movement.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2013-04-23T13:03:46Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0097476") +AnnotationAssertion(rdfs:label "spinal cord motor neuron migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (protein localization to non-motile cilium) + +AnnotationAssertion(Annotation( "GOC:cilia") Annotation( "GOC:kmv") Annotation( "PMID:23128241") "A process in which a protein is transported to, or maintained in, a location within a non-motile cilium.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2013-08-13T12:16:26Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "protein localization to nonmotile primary cilium") +AnnotationAssertion( "GO:0097499") +AnnotationAssertion(rdfs:label "protein localization to non-motile cilium") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (dendritic cell dendrite) + +AnnotationAssertion(Annotation( "CL:0000451") Annotation( "GOC:BHF") Annotation( "GOC:cjm") Annotation( "PMID:12200351") "A branched cellular projection (or cytoplasmic extension) that is extended from the surface of a dendritic immune cell, and which enables the cell to sample luminal pathogens and increase the surface area for antigen presentation to T cells.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2013-10-16T13:02:25Z") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0097511") +AnnotationAssertion(rdfs:label "dendritic cell dendrite") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (cardiac myofibril) + +AnnotationAssertion(Annotation( "GOC:cjm") Annotation( "GOC:devbiol") "A cardiac myofibril is a myofibril specific to cardiac muscle cells.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2013-10-16T13:04:58Z") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0097512") +AnnotationAssertion(rdfs:label "cardiac myofibril") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (sperm plasma membrane) + +AnnotationAssertion(Annotation( "GOC:cjm") "A plasma membrane that is part of a sperm cell.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2013-10-18T11:31:17Z") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0097524") +AnnotationAssertion(rdfs:label "sperm plasma membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (myeloid leukocyte migration) + +AnnotationAssertion(Annotation( "GOC:cvs") Annotation( "PMID:22342843") Annotation( "PMID:24157461") "The movement of a myeloid leukocyte within or between different tissues and organs of the body.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2013-11-11T13:59:43Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0097529") +AnnotationAssertion(rdfs:label "myeloid leukocyte migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (granulocyte migration) + +AnnotationAssertion(Annotation( "GOC:cvs") Annotation( "PMID:24163421") Annotation( "PMID:24193336") "The movement of a granulocyte within or between different tissues and organs of the body.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2013-11-11T14:00:44Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0097530") +AnnotationAssertion(rdfs:label "granulocyte migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (lymphoid lineage cell migration) + +AnnotationAssertion(Annotation( "GOC:pr") Annotation( "PMID:22342843") "The orderly movement of a lymphoid lineage cell from one site to another. A lymphoid lineage cell, also called a lymphoid lineage restricted progenitor cell, is a progenitor cell restricted to the lymphoid lineage.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2013-11-28T10:47:15Z") +AnnotationAssertion( "lymphoid lineage restricted progenitor cell migration") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0097534") +AnnotationAssertion(rdfs:label "lymphoid lineage cell migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (thymus epithelium morphogenesis) + +AnnotationAssertion(Annotation( "GOC:pr") Annotation( "PMID:22342843") "The process in which the thymus epithelium is generated and organized.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2013-11-28T10:51:03Z") +AnnotationAssertion( "thymic epithelium morphogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0097536") +AnnotationAssertion(rdfs:label "thymus epithelium morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (calcium ion transmembrane import into cytosol) + +AnnotationAssertion(Annotation( "GOC:vw") "A process in which a calcium ion is transported from one side of a membrane to the other into the cytosol by means of some agent such as a transporter or pore.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/23015"^^xsd:anyURI) +AnnotationAssertion( "pr") +AnnotationAssertion( "2014-01-23T11:05:13Z") +AnnotationAssertion( "GO:0060401") +AnnotationAssertion( "calcium transmembrane import into cytosol") +AnnotationAssertion( "cytosolic calcium ion transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0097553") +AnnotationAssertion(rdfs:label "calcium ion transmembrane import into cytosol") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (vacuole fusion) + +AnnotationAssertion(Annotation( "GOC:pr") Annotation( "GOC:vw") Annotation( "Wikipedia:Vacuole") "Merging of two or more vacuoles, or of vacuoles and vesicles within a cell to form a single larger vacuole.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2014-02-28T09:49:31Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0097576") +AnnotationAssertion(rdfs:label "vacuole fusion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (calcitonin family receptor activity) + +AnnotationAssertion(Annotation( "GOC:bhm") Annotation( "InterPro:IPR003287") Annotation( "PMID:10871296") Annotation( "PMID:12037140") Annotation( "PMID:18687416") "Combining with any member of the calcitonin family (e.g. adrenomedullin, adrenomedullin 2 (intermedin), amylin, calcitonin and calcitonin gene-related peptides (CGRPs)) to initiate a change in cell activity.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2014-09-08T15:32:19Z") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0097642") +AnnotationAssertion(rdfs:label "calcitonin family receptor activity") +SubClassOf( ) + +# Class: (calcitonin family binding) + +AnnotationAssertion(Annotation( "GOC:bhm") Annotation( "InterPro:IPR021116") Annotation( "PMID:10871296") Annotation( "PMID:12037140") Annotation( "PMID:18687416") "Binding to a member of the calcitonin family (e.g. adrenomedullin, adrenomedullin 2 (intermedin), amylin, calcitonin and calcitonin gene-related peptides (CGRPs)).") +AnnotationAssertion( "pr") +AnnotationAssertion( "2014-09-08T20:50:52Z") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0097644") +AnnotationAssertion(rdfs:label "calcitonin family binding") +SubClassOf( ) + +# Class: (G protein-coupled receptor complex) + +AnnotationAssertion(Annotation( "GOC:bhm") "A protein complex that contains G protein-coupled receptors.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2014-09-10T09:14:30Z") +AnnotationAssertion( "G-protein coupled receptor complex") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0097648") +AnnotationAssertion(rdfs:label "G protein-coupled receptor complex") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (intracellular vesicle) AnnotationAssertion(Annotation( "GOC:vesicles") "Any vesicle that is part of the intracellular region.") @@ -40663,9 +111429,62 @@ AnnotationAssertion( AnnotationAssertion( "cellular_component") AnnotationAssertion( "GO:0097708") AnnotationAssertion(rdfs:label "intracellular vesicle") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (ciliary basal body-plasma membrane docking) + +AnnotationAssertion(Annotation( "GOC:cilia") Annotation( "PMID:13978319") Annotation( "PMID:23348840") Annotation( "PMID:23530209") Annotation( "PMID:25686250") Annotation( "PMID:26981235") Annotation( "Reactome:R-HSA-5620912.1") "The docking of a cytosolic centriole/basal body to the plasma membrane via the ciliary transition fibers. In some species this may happen via an intermediate step, by first docking to the ciliary vesicle via the ciliary transition fibers. The basal body-ciliary vesicle then relocates to the plasma membrane, followed by the ciliary vesicle fusing with the plasma membrane, effectively attaching the basal body to the plasma membrane.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2016-08-05T16:12:33Z") +AnnotationAssertion( "Reactome:R-HSA-5620912.1") +AnnotationAssertion( "ciliary basal body docking") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "anchoring of the basal body to the plasma membrane") +AnnotationAssertion( "GO:0097711") +AnnotationAssertion(rdfs:comment "Basal bodies in jawed vertebrates appear to first attach to a ciliary vesicle. It is unclear how specific this is to jawed vertebrates or if other organisms also employ this sequence. Some species like Giardia intestinalis do not relocate their basal bodies to the plasma membrane, but have their axonemes extend through the cytosol to then protrude out of the cell to form flagella.") +AnnotationAssertion(rdfs:label "ciliary basal body-plasma membrane docking") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (vesicle targeting, trans-Golgi to periciliary membrane compartment) + +AnnotationAssertion(Annotation( "GOC:cilia") Annotation( "PMID:20106869") Annotation( "PMID:23351793") Annotation( "PMID:24814148") Annotation( "PMID:26485645") Annotation( "Reactome:R-HSA-5620920.1") "The process in which vesicles formed at the trans-Golgi network are directed to the plasma membrane surrounding the base of the cilium, including the ciliary pocket, mediated by molecules at the vesicle membrane and target membrane surfaces.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2016-08-05T16:16:28Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0097712") +AnnotationAssertion(rdfs:label "vesicle targeting, trans-Golgi to periciliary membrane compartment") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (neural tissue regeneration) + +AnnotationAssertion(Annotation( "Wikipedia:Neuroregeneration") "The regrowth of neural tissue following its loss or destruction.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2016-08-25T13:14:27Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "neuroregeneration") +AnnotationAssertion( "GO:0097719") +AnnotationAssertion(rdfs:label "neural tissue regeneration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (sperm motility) + +AnnotationAssertion(Annotation( "GOC:cilia") Annotation( "GOC:krc") "Any process involved in the controlled movement of a sperm cell.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2016-09-01T12:00:45Z") +AnnotationAssertion( "sperm movement") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0097722") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "sperm motility") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + # Class: (non-motile cilium) AnnotationAssertion(Annotation( "GOC:cilia") Annotation( "GOC:dgh") Annotation( "GOC:kmv") Annotation( "PMID:17009929") Annotation( "PMID:20144998") Annotation( "PMID:22118931") "A cilium which may have a variable array of axonemal microtubules but does not contain molecular motors.") @@ -40710,6 +111529,105 @@ SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (extracellular exosome biogenesis) + +AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:bf") Annotation( "PMID:19442504") Annotation( "PMID:25392495") "The assembly and secretion of an extracellular exosome, a membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2016-10-03T14:35:25Z") +AnnotationAssertion( "exosome assembly or secretion") +AnnotationAssertion( "exosome biogenesis") +AnnotationAssertion( "exosome production") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "ILV assembly") +AnnotationAssertion( "intraluminal vesicle assembly") +AnnotationAssertion( "GO:0097734") +AnnotationAssertion(rdfs:label "extracellular exosome biogenesis") +SubClassOf( ) + +# Class: (excitatory neuromuscular junction) + +AnnotationAssertion(Annotation( "GOC:dos") "The junction between the axon of a motor neuron and a muscle fiber. In response to the arrival of action potentials, the presynaptic button releases molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane of the muscle fiber, leading to a post-synaptic potential responsible for muscle contraction.") +AnnotationAssertion( "dos") +AnnotationAssertion( "2013-10-14T12:02:51Z") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0098520") +AnnotationAssertion(rdfs:label "excitatory neuromuscular junction") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (neuromuscular junction of skeletal muscle fiber) + +AnnotationAssertion(Annotation( "GOC:dos") "A neuromuscular junction in which the target muscle cell is a skeletal muscle fiber.") +AnnotationAssertion( "dos") +AnnotationAssertion( "2013-10-14T12:04:32Z") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0098522") +AnnotationAssertion(rdfs:comment "In vertebrates, the term 'neuromuscular junction' is limited to synapses targeting skeletal muscle fibers - all of which are cholinergic and excitatory. Both inhibitory and excitatory neuromuscular junctions exist in invertebrates, utilizing a range of neurotransmitters including glutamate, GABA and 5-HT.") +AnnotationAssertion(rdfs:label "neuromuscular junction of skeletal muscle fiber") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (neuromuscular junction of myotube) + +AnnotationAssertion(Annotation( "GOC:dos") "A neuromuscular junction in which the target muscle cell is a myotube.") +AnnotationAssertion( "dos") +AnnotationAssertion( "2013-10-14T12:05:12Z") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0098523") +AnnotationAssertion(rdfs:comment "In vertebrates, the term 'neuromuscular junction' is limited to synapses targeting the myotubes of skeletal muscle (AKA skeletal muscle fibers). Neuromuscular junctions targeting other muscle cell types exist in invertebrates such as the mononucleate somatic muscles of nematodes.") +AnnotationAssertion(rdfs:label "neuromuscular junction of myotube") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (neuromuscular junction of somatic muscle myotube) + +AnnotationAssertion(Annotation( "GOC:dos") "A neuromuscular junction in which the target muscle cell is a somatic muscle myotube, such as an arthropod somatic muscle cell.") +AnnotationAssertion( "dos") +AnnotationAssertion( "2013-10-14T12:05:43Z") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0098524") +AnnotationAssertion(rdfs:label "neuromuscular junction of somatic muscle myotube") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (excitatory neuromuscular junction of somatic myotube) + +AnnotationAssertion(Annotation( "GOC:dos") "A neuromuscular junction that functions in the excitation of somatic muscle myotubes, such as an arthropod somatic muscle cells.") +AnnotationAssertion( "dos") +AnnotationAssertion( "2013-10-14T12:06:08Z") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0098525") +AnnotationAssertion(rdfs:label "excitatory neuromuscular junction of somatic myotube") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (neuromuscular junction of somatic muscle) + +AnnotationAssertion(Annotation( "GOC:dos") "A neuromuscular junction in which the target muscle cell is a somatic muscle cell, such as those found in nematodes and arthropods.") +AnnotationAssertion( "dos") +AnnotationAssertion( "2013-10-14T12:07:05Z") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0098527") +AnnotationAssertion(rdfs:label "neuromuscular junction of somatic muscle") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (skeletal muscle fiber differentiation) + +AnnotationAssertion(Annotation( "GOC:dos") "The process in which a relatively unspecialized cell acquires specialized features of a skeletal muscle fiber cell. Skeletal muscle fiber differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual skeletal muscle fibers fuse to form bigger myotubes and start to contract.") +AnnotationAssertion( "dos") +AnnotationAssertion( "2013-10-15T14:00:34Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0098528") +AnnotationAssertion(rdfs:label "skeletal muscle fiber differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (neuromuscular junction development, skeletal muscle fiber) + +AnnotationAssertion(Annotation( "GOC:mtg_OBO2OWL_2013") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a neuromuscular junction that targets a skeletal muscle fiber.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0098529") +AnnotationAssertion(rdfs:label "neuromuscular junction development, skeletal muscle fiber") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (defense response to other organism) AnnotationAssertion(Annotation( "GOC:dos") "Reactions triggered in response to the presence of another organism that act to protect the cell or organism from damage caused by that organism.") @@ -40726,8 +111644,30 @@ AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "defense response to other organism") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (maintenance of protein complex location) + +AnnotationAssertion(Annotation( "GOC:dos") "Any process in which a protein complex is maintained in a location and prevented from moving elsewhere. These include sequestration, stabilization to prevent transport elsewhere and the active retrieval of protein complexes that move away.") +AnnotationAssertion( "dos") +AnnotationAssertion( "2013-11-15T18:20:16Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0098544") +AnnotationAssertion(rdfs:label "maintenance of protein complex location") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (maintenance of protein complex location in cytoplasm) + +AnnotationAssertion(Annotation( "GOC:dos") "Any process in which a protein complex is maintained in a specific location within the cytoplasm and is prevented from moving elsewhere.") +AnnotationAssertion( "dos") +AnnotationAssertion( "2013-11-15T20:49:15Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0098545") +AnnotationAssertion(rdfs:label "maintenance of protein complex location in cytoplasm") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + # Class: (learned vocalization behavior) AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dos") Annotation( "GOC:rl") Annotation( "PMID:16418265") Annotation( "PMID:17035521") "A vocalization behavior that is the result of learning.") @@ -40740,6 +111680,31 @@ AnnotationAssertion(rdfs:label "lear SubClassOf( ) SubClassOf( ) +# Class: (bounding membrane of organelle) + +AnnotationAssertion(Annotation( "GOC:dos") "The lipid bilayer that forms the outer-most layer of an organelle.") +AnnotationAssertion( "dos") +AnnotationAssertion( "2014-02-26T13:41:31Z") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0098588") +AnnotationAssertion(rdfs:comment "Examples include the outer membranes of double membrane bound organelles such as mitochondria as well as the bounding membranes of single-membrane bound organelles such as lysosomes.") +AnnotationAssertion(rdfs:label "bounding membrane of organelle") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (plasma membrane region) + +AnnotationAssertion(Annotation( "GOC:dos") "A membrane that is a (regional) part of the plasma membrane.") +AnnotationAssertion( "dos") +AnnotationAssertion( "2014-03-06T11:55:32Z") +AnnotationAssertion( "region of plasma membrane") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0098590") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:comment "Note that this term should not be used for direct manual annotation as it should always be possible to choose a more specific subclass.") +AnnotationAssertion(rdfs:label "plasma membrane region") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (learned vocalization behavior or vocal learning) AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:dos") Annotation( "GOC:rl") Annotation( "PMID:16418265") Annotation( "PMID:17035521") "Vocalisation behavior that is the result of learning, or the process by which new vocalizations are learned.") @@ -40795,7 +111760,6 @@ AnnotationAssertion( "GO:0098633") AnnotationAssertion(rdfs:label "collagen fibril binding") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -SubClassOf( ) # Class: (protein complex involved in cell-cell adhesion) @@ -40829,6 +111793,7 @@ AnnotationAssertion(Annotation( "cellular_component") AnnotationAssertion( "GO:0098642") AnnotationAssertion(rdfs:label "network-forming collagen trimer") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) @@ -40870,9 +111835,306 @@ AnnotationAssertion(Annotation( "cellular_component") AnnotationAssertion( "GO:0098651") AnnotationAssertion(rdfs:label "basement membrane collagen trimer") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (monoatomic cation transmembrane transport) + +AnnotationAssertion(Annotation( "GOC:dos") Annotation( "GOC:vw") "The process in which a monoatomic cation is transported across a membrane. Monatomic cations (also called simple cations) are positively charged ions consisting of exactly one atom.") +AnnotationAssertion( "GO:0099132") +AnnotationAssertion( "cation transmembrane transport") +AnnotationAssertion( "ATP hydrolysis coupled cation transmembrane transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0098655") +AnnotationAssertion(rdfs:label "monoatomic cation transmembrane transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (import into cell) + +AnnotationAssertion(Annotation( "GOC:dos") "The directed movement of some substance from outside of a cell into a cell. This may occur via transport across the plasma membrane or via endocytosis.") +AnnotationAssertion( "uptake") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0098657") +AnnotationAssertion(rdfs:label "import into cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (inorganic anion import across plasma membrane) + +AnnotationAssertion(Annotation( "GOC:dos") "The directed movement of inorganic anions from outside of a cell, across the plasma membrane and into the cytosol.") +AnnotationAssertion( "inorganic anion import into cell") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0098658") +AnnotationAssertion(rdfs:label "inorganic anion import across plasma membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (inorganic cation import across plasma membrane) + +AnnotationAssertion(Annotation( "GOC:dos") "The directed movement of inorganic cations from outside of a cell, across the plasma membrane and into the cytosol.") +AnnotationAssertion( "inorganic cation import into cell") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0098659") +AnnotationAssertion(rdfs:label "inorganic cation import across plasma membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (inorganic ion transmembrane transport) + +AnnotationAssertion(Annotation( "GOC:mah") "The process in which an inorganic ion is transported across a membrane.") +AnnotationAssertion( "inorganic ion membrane transport") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "transmembrane inorganic ion transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0098660") +AnnotationAssertion(rdfs:comment "Note that this term is not intended for use in annotating lateral movement within membranes.") +AnnotationAssertion(rdfs:label "inorganic ion transmembrane transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (inorganic anion transmembrane transport) + +AnnotationAssertion(Annotation( "GOC:mah") "The process in which an inorganic anion is transported across a membrane.") +AnnotationAssertion( "inorganic anion membrane transport") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "transmembrane inorganic anion transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0098661") +AnnotationAssertion(rdfs:comment "Note that this term is not intended for use in annotating lateral movement within membranes.") +AnnotationAssertion(rdfs:label "inorganic anion transmembrane transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (inorganic cation transmembrane transport) + +AnnotationAssertion(Annotation( "GOC:mah") "A process in which an inorganic cation is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.") +AnnotationAssertion( "GO:0015672") +AnnotationAssertion( "GO:0072511") +AnnotationAssertion( "inorganic cation membrane transport") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "transmembrane inorganic cation transport") +AnnotationAssertion( "divalent inorganic cation transport") +AnnotationAssertion( "monovalent inorganic cation transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0098662") +AnnotationAssertion(rdfs:comment "Note that this term is not intended for use in annotating lateral movement within membranes.") +AnnotationAssertion(rdfs:label "inorganic cation transmembrane transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (G protein-coupled serotonin receptor signaling pathway) + +AnnotationAssertion(Annotation( "GOC:mah") "The series of molecular signals generated as a consequence of a G protein-coupled serotonin receptor binding to one of its physiological ligands.") +AnnotationAssertion( "dos") +AnnotationAssertion( "2016-12-21T12:07:58Z") +AnnotationAssertion( "G-protein coupled serotonin receptor signaling pathway") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0098664") +AnnotationAssertion(rdfs:label "G protein-coupled serotonin receptor signaling pathway") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (serotonin receptor complex) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:bhm") Annotation( "GO_REF:0000088") Annotation( "PMID:16116092") "A protein complex that is capable of serotonin receptor activity.") +AnnotationAssertion( "dos") +AnnotationAssertion( "2016-12-21T12:24:56Z") +AnnotationAssertion( "5-HT receptor complex") +AnnotationAssertion( "5-hydroxytryptamine receptor complex") +AnnotationAssertion( "5HT receptor complex") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0098665") +AnnotationAssertion(rdfs:label "serotonin receptor complex") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (G protein-coupled serotonin receptor complex) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:bhm") Annotation( "GO_REF:0000088") "A protein complex that is capable of G protein-coupled serotonin receptor activity.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/12942"^^xsd:anyURI) +AnnotationAssertion( "dos") +AnnotationAssertion( "2016-12-21T12:28:12Z") +AnnotationAssertion( "G-protein coupled serotonin receptor complex") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0098666") +AnnotationAssertion(rdfs:label "G protein-coupled serotonin receptor complex") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (dopaminergic synapse) + +AnnotationAssertion(Annotation( "GOC:dos") "A synapse that uses dopamine as a neurotransmitter.") +AnnotationAssertion( "dos") +AnnotationAssertion( "2017-03-07T14:51:52Z") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0098691") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "dopaminergic synapse") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of synaptic vesicle cycle) + +AnnotationAssertion(Annotation( "GOC:dos") "Any process that modulates the frequency, rate or extent of the synaptic vesicle cycle.") +AnnotationAssertion( "dos") +AnnotationAssertion( "2017-03-21T16:06:48Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0098693") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "regulation of synaptic vesicle cycle") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (adenine import across plasma membrane) + +AnnotationAssertion(Annotation( "GOC:dos") "The directed movement of adenine from outside of a cell, across the plasma membrane and into the cytosol.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2012-12-06T14:51:42Z") +AnnotationAssertion( "GO:0061488") +AnnotationAssertion( "adenine import into cell") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0098702") +AnnotationAssertion(rdfs:label "adenine import across plasma membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (calcium ion import across plasma membrane) + +AnnotationAssertion(Annotation( "GOC:dos") "The directed movement of calcium ions from outside of a cell, across the plasma membrane and into the cytosol.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2013-02-07T13:07:59Z") +AnnotationAssertion( "GO:1990035") +AnnotationAssertion( "calcium ion import into cell") +AnnotationAssertion(Annotation( "GOC:vw") "calcium ion uptake into cell") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0098703") +AnnotationAssertion(rdfs:label "calcium ion import across plasma membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (carbohydrate import across plasma membrane) + +AnnotationAssertion(Annotation( "GOC:dos") "The directed movement of a carbohydrate from outside of a cell, across the plasma membrane and into the cytosol.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2012-05-31T02:45:02Z") +AnnotationAssertion( "GO:0097319") +AnnotationAssertion( "carbohydrate import into cell") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0098704") +AnnotationAssertion(rdfs:label "carbohydrate import across plasma membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (glucose import across plasma membrane) + +AnnotationAssertion(Annotation( "GOC:dos") "The directed movement of glucose from outside of a cell, across the plasma membrane and into the cytosol.") +AnnotationAssertion( "al") +AnnotationAssertion( "2012-12-06T14:54:07Z") +AnnotationAssertion( "GO:0061490") +AnnotationAssertion( "GO:1990821") +AnnotationAssertion( "glucose import into cell") +AnnotationAssertion( "high affinity glucose import") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0098708") +AnnotationAssertion(rdfs:label "glucose import across plasma membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (iron ion import across plasma membrane) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "PMID:8321236") "The directed movement of iron ions from outside of a cell, across the plasma membrane and into the cytosol.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2012-12-20T08:29:00Z") +AnnotationAssertion( "GO:0097459") +AnnotationAssertion( "GO:0097460") +AnnotationAssertion( "GO:0098707") +AnnotationAssertion( "iron ion import into cell") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:mah") "ferrous ion import into cell") +AnnotationAssertion( "ferrous iron import across plasma membrane") +AnnotationAssertion( "ferrous iron import into cell") +AnnotationAssertion(Annotation( "GOC:mah") "iron import into cell") +AnnotationAssertion( "GO:0098711") +AnnotationAssertion(rdfs:label "iron ion import across plasma membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (L-glutamate import across plasma membrane) + +AnnotationAssertion(Annotation( "GOC:dos") "The directed movement of L-glutamate from outside of a cell, across the plasma membrane and into the cytosol.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2013-06-12T12:32:47Z") +AnnotationAssertion( "GO:1903802") +AnnotationAssertion( "GO:1990123") +AnnotationAssertion( "L-glutamate(1-) import across plasma membrane") +AnnotationAssertion( "L-glutamate import into cell") +AnnotationAssertion( "L-glutamate(1-) import into cell") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0098712") +AnnotationAssertion(rdfs:label "L-glutamate import across plasma membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (sodium ion import across plasma membrane) + +AnnotationAssertion(Annotation( "GOC:dos") "The directed movement of sodium ions from outside of a cell, across the plasma membrane and into the cytosol.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2012-08-03T16:55:52Z") +AnnotationAssertion( "GO:0097369") +AnnotationAssertion( "GO:1990118") +AnnotationAssertion( "sodium import") +AnnotationAssertion( "sodium ion import into cell") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "sodium ion import") +AnnotationAssertion( "GO:0098719") +AnnotationAssertion(rdfs:label "sodium ion import across plasma membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (asymmetric stem cell division) + +AnnotationAssertion(Annotation( "GOC:dos") Annotation( "PMID:18513950") "Division of a stem cell during which it retains its identity and buds off a daughter cell with a new identity.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0098722") +AnnotationAssertion(rdfs:label "asymmetric stem cell division") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (skeletal muscle myofibril) + +AnnotationAssertion(Annotation( "GOC:dos") "A myofibril of a skeletal muscle fiber.") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0098723") +AnnotationAssertion(rdfs:label "skeletal muscle myofibril") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (maintenance of cell number) + +AnnotationAssertion(Annotation( "GOC:dos") "Any process by which the numbers of cells of a particular type or in a tissue are maintained.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0098727") +AnnotationAssertion(rdfs:label "maintenance of cell number") +SubClassOf( ) + +# Class: (germline stem cell asymmetric division) + +AnnotationAssertion(Annotation( "GOC:dos") "The self-renewing division of a germline stem cell, to produce a daughter stem cell and a daughter germ cell which will divide to form one or more gametes.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0098728") +AnnotationAssertion(rdfs:label "germline stem cell asymmetric division") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (import across plasma membrane) + +AnnotationAssertion(Annotation( "GOC:dos") "The directed movement of some substance from outside of a cell, across the plasma membrane and into the cytosol.") +AnnotationAssertion( "uptake") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0098739") +AnnotationAssertion(rdfs:label "import across plasma membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (cerebellar neuron development) + +AnnotationAssertion(Annotation( "GOC:dos") "The process whose specific outcome is the progression of a cerebellar neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0098749") +AnnotationAssertion(rdfs:label "cerebellar neuron development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (bone cell development) + +AnnotationAssertion(Annotation( "GOC:dos") "The process whose specific outcome is the progression of a bone cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0098751") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:comment "Not to be used for manual annotation. Please choose a more specific cell development term or if not possible, bone or bone tissue development.") +AnnotationAssertion(rdfs:label "bone cell development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (detoxification) AnnotationAssertion(Annotation( "GOC:dos") "Any process that reduces or removes the toxicity of a toxic substance. These may include transport of the toxic substance away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance.") @@ -40885,6 +112147,26 @@ AnnotationAssertion(rdfs:label "deto SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (inorganic ion homeostasis) + +AnnotationAssertion(Annotation( "GOC:dos") "Any process involved in the maintenance of an internal steady state of inorganic ions within an organism or cell.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/24455"^^xsd:anyURI) +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0098771") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "inorganic ion homeostasis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (skin epidermis development) + +AnnotationAssertion(Annotation( "GOC:dos") "The process whose specific outcome is the progression of the skin epidermis over time, from its formation to the mature structure.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0098773") +AnnotationAssertion(rdfs:label "skin epidermis development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (presynapse) AnnotationAssertion(Annotation( "GOC:dos") "The part of a synapse that is part of the presynaptic cell.") @@ -40908,14 +112190,84 @@ SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (membrane protein complex) + +AnnotationAssertion(Annotation( "GOC:dos") "Any protein complex that is part of a membrane.") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0098796") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "membrane protein complex") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (plasma membrane protein complex) + +AnnotationAssertion(Annotation( "GOC:dos") "Any protein complex that is part of the plasma membrane.") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0098797") +AnnotationAssertion(rdfs:label "plasma membrane protein complex") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (regulation of renal system process) AnnotationAssertion(Annotation( "GOC:dos") "Any process that modulates the frequency, rate or extent of a system process, a multicellular organismal process carried out by the renal system.") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0098801") AnnotationAssertion(rdfs:label "regulation of renal system process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (plasma membrane signaling receptor complex) + +AnnotationAssertion(Annotation( "GOC:dos") "Any protein complex that is part of the plasma membrane and which functions as a signaling receptor.") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0098802") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:comment "Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.") +AnnotationAssertion(rdfs:label "plasma membrane signaling receptor complex") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (non-motile cilium membrane) + +AnnotationAssertion(Annotation( "GOC:cilia") Annotation( "GOC:dos") "The portion of the plasma membrane surrounding a non-motile cilium.") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "nonmotile primary cilium membrane") +AnnotationAssertion( "GO:0098804") +AnnotationAssertion(rdfs:label "non-motile cilium membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (nuclear chromosome segregation) + +AnnotationAssertion(Annotation( "GOC:dos") "The process in which genetic material, in the form of nuclear chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. Nuclear chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0098813") +AnnotationAssertion(rdfs:label "nuclear chromosome segregation") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (modulation of excitatory postsynaptic potential) + +AnnotationAssertion(Annotation( "GOC:dos") "Any process that modulates the frequency, rate or extent of excitatory postsynaptic potential (EPSP). EPSP is a process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0098815") +AnnotationAssertion(rdfs:label "modulation of excitatory postsynaptic potential") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (protein transport along microtubule) + +AnnotationAssertion(Annotation( "PMID:25987607") "The directed movement of a protein along a microtubule, mediated by motor proteins.") +AnnotationAssertion( "microtubule-based protein transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0098840") +AnnotationAssertion(rdfs:label "protein transport along microtubule") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + # Class: (podocyte foot) AnnotationAssertion(Annotation( "PMID:25324828") "A cell projection of a podocyte (glomerular visceral epithelial cell) forming a foot-like structure projecting from a podocyte primary projection, that wraps around capillaries of a renal glomerulus. Adjacent feet (pedicels) interdigitate, leaving thin filtration slits between them, which are covered by slit diaphragms.") @@ -40929,6 +112281,14 @@ AnnotationAssertion(rdfs:label "podo SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (lytic vacuole membrane) + +AnnotationAssertion(Annotation( "GOC:dos") "The lipid bilayer surrounding a lytic vacuole and separating its contents from the cytoplasm of the cell.") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0098852") +AnnotationAssertion(rdfs:label "lytic vacuole membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (actin-based cell projection) AnnotationAssertion(Annotation( "PMID:15661519") "A cell projection supported by an assembly of actin filaments, and which lacks microtubules.") @@ -40938,14 +112298,444 @@ AnnotationAssertion(rdfs:label "acti SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (intramembranous bone growth) + +AnnotationAssertion(Annotation( "PMID:26399686") "The increase in size or mass of an intramembranous bone that contributes to the shaping of the bone.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0098867") +AnnotationAssertion(rdfs:label "intramembranous bone growth") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (bone growth) + +AnnotationAssertion(Annotation( "GOC:dos") "The increase in size or mass of a bone that contributes to the shaping of that bone.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0098868") +AnnotationAssertion(rdfs:label "bone growth") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (postsynaptic actin cytoskeleton) + +AnnotationAssertion(Annotation( "GOC:dos") "The actin cytoskeleton that is part of a postsynapse.") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0098871") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "postsynaptic actin cytoskeleton") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (vesicle-mediated transport to the plasma membrane) + +AnnotationAssertion(Annotation( "GOC:dos") "The directed movement of substances to the plasma membrane in transport vesicles that fuse with the plasma membrane by exocytosis.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0098876") +AnnotationAssertion(rdfs:label "vesicle-mediated transport to the plasma membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (neurotransmitter receptor transport to plasma membrane) + +AnnotationAssertion(Annotation( "GOC:dos") "The directed movement of neurotransmitter receptor to the plasma membrane in transport vesicles.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0098877") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "neurotransmitter receptor transport to plasma membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (neurotransmitter receptor complex) + +AnnotationAssertion(Annotation( "GOC:dos") "Any protein complex that is capable of functioning as a neurotransmitter receptor.") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0098878") +AnnotationAssertion(rdfs:label "neurotransmitter receptor complex") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (synapse pruning) + +AnnotationAssertion(Annotation( "GOC:dos") Annotation( "PMID:12062020") Annotation( "PMID:18083105") Annotation( "PMID:22632716") Annotation( "PMID:29844190") "A cellular process that results in the controlled breakdown of synapse. After it starts the process is continuous until the synapse has disappeared.") +AnnotationAssertion(Annotation( "GOC:aruk") Annotation( "GOC:bc") Annotation( "PMID:22632716") "synapse clearance") +AnnotationAssertion(Annotation( "PMID:12062020") Annotation( ) "synapse disassembly") +AnnotationAssertion(Annotation( "GOC:aruk") Annotation( "GOC:bc") Annotation( "PMID:18083105") Annotation( "PMID:29844190") "synapse elimination") +AnnotationAssertion(Annotation( "GOC:aruk") Annotation( "GOC:bc") Annotation( "PMID:22632716") "synapse removal") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0098883") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "synapse pruning") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of action potential) + +AnnotationAssertion(Annotation( "GOC:dos") Annotation( "GOC:dph") Annotation( "GOC:go_curators") Annotation( "GOC:tb") Annotation( "ISBN:978-0-07-139011-8") "Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0098900") +AnnotationAssertion(rdfs:comment "The ion channels through which current flows during an action potential should be annotated to the process 'action potential'. Gene products involved in modulating the characteristics of an action potential via changing the expression levels or the activity of these channels (e.g. modulating their kinetics or voltage sensitivity) should be annotated to this regulation term.") +AnnotationAssertion(rdfs:label "regulation of action potential") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of cardiac muscle cell action potential) + +AnnotationAssertion(Annotation( "GOC:dos") Annotation( "GOC:mtg_cardiac_conduct_nov11") "Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a cardiac muscle cell. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0098901") +AnnotationAssertion(rdfs:label "regulation of cardiac muscle cell action potential") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of AV node cell action potential) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mtg_cardiac_conduct_nov11") "Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in an atrioventricular node myocyte. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2011-11-10T08:58:56Z") +AnnotationAssertion( "regulation of AV node cardiac muscle cell action potential") +AnnotationAssertion( "regulation of atrioventricular node cardiac muscle cell action potential") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0098904") +AnnotationAssertion(rdfs:label "regulation of AV node cell action potential") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (regulation of bundle of His cell action potential) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mtg_cardiac_conduct_nov11") "Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a cardiac muscle cell of the bundle of His. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2011-11-15T12:01:18Z") +AnnotationAssertion( "regulation of bundle of His cardiac muscle cell action potential") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0098905") +AnnotationAssertion(rdfs:label "regulation of bundle of His cell action potential") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of Purkinje myocyte action potential) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mtg_cardiac_conduct_nov11") "Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a Purkinje myocyte. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2011-11-10T08:58:56Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0098906") +AnnotationAssertion(rdfs:label "regulation of Purkinje myocyte action potential") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (regulation of SA node cell action potential) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mtg_cardiac_conduct_nov11") "Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in an SA node cardiac myocyte. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2011-11-10T08:50:15Z") +AnnotationAssertion( "regulation of SA node cardiac muscle cell action potential") +AnnotationAssertion( "regulation of SAN cardiac muscle cell action potential") +AnnotationAssertion( "regulation of sinoatrial node cardiac muscle cell action potential") +AnnotationAssertion( "regulation of sinus node cardiac muscle cell action potential") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0098907") +AnnotationAssertion(rdfs:label "regulation of SA node cell action potential") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (regulation of neuronal action potential) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:isa_complete") Annotation( "GOC:tb") "Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a neuron. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "generation of action potential") +AnnotationAssertion( "GO:0098908") +AnnotationAssertion(rdfs:label "regulation of neuronal action potential") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (anterograde trans-synaptic signaling) + +AnnotationAssertion(Annotation( "GOC:dos") "Cell-cell signaling from pre to post-synapse, across the synaptic cleft.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0098916") +AnnotationAssertion(rdfs:label "anterograde trans-synaptic signaling") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (retrograde trans-synaptic signaling) + +AnnotationAssertion(Annotation( "GOC:dos") "Cell-cell signaling from post to pre-synapse, across the synaptic cleft.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0098917") +AnnotationAssertion(rdfs:label "retrograde trans-synaptic signaling") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (retrograde trans-synaptic signaling by lipid) + +AnnotationAssertion(Annotation( "GOC:dos") "Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by a lipid ligand.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0098920") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "retrograde trans-synaptic signaling by lipid") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (postsynaptic signal transduction) + +AnnotationAssertion(Annotation( "GOC:dos") "Signal transduction in which the initial step occurs in a postsynapse.") +AnnotationAssertion(Annotation( ) "postsynaptic signaling pathway") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0098926") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "postsynaptic signal transduction") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (presynaptic signal transduction) + +AnnotationAssertion(Annotation( "GOC:dos") "Signal transduction in which the initial step occurs in a presynapse.") +AnnotationAssertion(Annotation( ) "presynaptic signaling pathway") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0098928") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "presynaptic signal transduction") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (axonal transport) + +AnnotationAssertion(Annotation( "ISBN:0815316194") "The directed movement of organelles or molecules along microtubules in axons.") +AnnotationAssertion( "Wikipedia:Axoplasmic_transport") +AnnotationAssertion( "axon cargo transport") +AnnotationAssertion( "axoplasmic transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0098930") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "axonal transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (retrograde dendritic transport) + +AnnotationAssertion(Annotation( "GOC:dos") "The directed movement of organelles or molecules along microtubules in a dendrite from the postsynapse towards the cell body.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0098934") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "retrograde dendritic transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (dendritic transport) + +AnnotationAssertion(Annotation( "ISBN:0815316194") "The directed movement of organelles or molecules along microtubules in dendrites.") +AnnotationAssertion( "dendrite cargo transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0098935") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "dendritic transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (anterograde dendritic transport) + +AnnotationAssertion(Annotation( "ISBN:0815316194") "The directed movement of organelles or molecules along microtubules from the cell body toward the postsynapse in dendrites.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0098937") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "anterograde dendritic transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (postsynaptic neurotransmitter receptor activity) + +AnnotationAssertion(Annotation( "GOC:dos") Annotation( "GOC:signaling") "Neurotransmitter receptor activity occuring in the postsynaptic membrane during synaptic transmission.") +AnnotationAssertion( "neurotransmitter receptor activity involved in chemical synaptic transmission") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0098960") +AnnotationAssertion(rdfs:label "postsynaptic neurotransmitter receptor activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (dendritic transport of ribonucleoprotein complex) + +AnnotationAssertion(Annotation( "GOC:dos") "The directed movement of a ribonucleoprotein complex along microtubules in nerve cell dendrites.") +AnnotationAssertion( "dendritic transport of RNP complex") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0098961") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "dendritic transport of ribonucleoprotein complex") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (regulation of postsynaptic neurotransmitter receptor activity) + +AnnotationAssertion(Annotation( "GOC:dos") "Any process that modulates the frequency, rate or extent of neurotransmitter receptor activity involved in synaptic transmission. Modulation may be via an effect on ligand affinity, or effector funtion such as ion selectivity or pore opening/closing in ionotropic receptors.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0098962") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "regulation of postsynaptic neurotransmitter receptor activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (exocytic insertion of neurotransmitter receptor to postsynaptic membrane) + +AnnotationAssertion(Annotation( "PMID:19503082") "The exocytic fusion of neurotransmitter receptor containing vesicles with the postsynaptic membrane resulting in the integration of NT receptors, enabling them to participate in neurotransmitter reception. This process includes tethering and docking steps that prepare vesicles for fusion.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0098967") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "exocytic insertion of neurotransmitter receptor to postsynaptic membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (neurotransmitter receptor transport to postsynaptic membrane) + +AnnotationAssertion(Annotation( "GOC:dos") "The directed movement of neurotransmitter receptor to the postsynaptic membrane in transport vesicles.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0098969") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "neurotransmitter receptor transport to postsynaptic membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (anterograde dendritic transport of neurotransmitter receptor complex) + +AnnotationAssertion(Annotation( "GOC:dos") "The directed movement of a neurotransmitter receptor complex along microtubules in nerve cell dendrites towards the postsynapse.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0098971") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "anterograde dendritic transport of neurotransmitter receptor complex") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (postsynaptic actin cytoskeleton organization) + +AnnotationAssertion(Annotation( "GOC:dos") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins in the postsynaptic actin cytoskeleton.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0098974") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "postsynaptic actin cytoskeleton organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (postsynapse of neuromuscular junction) + +AnnotationAssertion(Annotation( "GOC:dos") Annotation( "Wikipedia:Neuromuscular_junction&oldid=723623502") "The postsynapse of a neuromuscular junction. In vertebrate muscles this includes the motor end-plate, consisting of postjunctional folds of the sarcolemma.") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0098975") +AnnotationAssertion(rdfs:label "postsynapse of neuromuscular junction") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + # Class: (excitatory chemical synaptic transmission) AnnotationAssertion(Annotation( "GOC:dos") "Synaptic transmission that results in an excitatory postsynaptic potential.") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0098976") AnnotationAssertion(rdfs:label "excitatory chemical synaptic transmission") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (glutamatergic synapse) + +AnnotationAssertion(Annotation( "GOC:dos") "A synapse that uses glutamate as a neurotransmitter.") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0098978") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "glutamatergic synapse") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (cholinergic synapse) + +AnnotationAssertion(Annotation( "GOC:dos") "A synapse that uses acetylcholine as a neurotransmitter.") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0098981") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "cholinergic synapse") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (GABA-ergic synapse) + +AnnotationAssertion(Annotation( "GOC:dos") "A synapse that uses GABA as a neurotransmitter. These synapses are typically inhibitory.") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0098982") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "GABA-ergic synapse") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (G protein-coupled glutamate receptor activity) + +AnnotationAssertion(Annotation( "GOC:dos") "Combining with glutamate and transmitting a signal from one side of the membrane to the other by activating an associated G-protein, initiating a change in cell activity.") +AnnotationAssertion( "G-protein coupled glutamate receptor activity") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0098988") +AnnotationAssertion(rdfs:label "G protein-coupled glutamate receptor activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (neuronal dense core vesicle) + +AnnotationAssertion(Annotation( "GOC:dos") Annotation( "ISBN:978-0-07-181001-2") Annotation( "Wikipedia:Neuropeptide&oldid=713905176") "A dense core vesicle (granule) that is part of a neuron. These vesicles typically contain neuropeptides. They can be found in all parts of neurons, including the soma, dendrites, axonal swellings (varicosities) and synaptic terminals.") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0098992") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "neuronal dense core vesicle") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (vesicle-mediated transport in synapse) + +AnnotationAssertion(Annotation( "GOC:dos") "Any vesicle-mediated transport that occurs in a synapse.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0099003") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "vesicle-mediated transport in synapse") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectAllValuesFrom( )) + +# Class: (neuronal dense core vesicle membrane) + +AnnotationAssertion(Annotation( "GOC:dos") "The lipid bilayer surrounding a neuronal dense core vesicle.") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0099012") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "neuronal dense core vesicle membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (neuronal dense core vesicle organization) + +AnnotationAssertion(Annotation( "GOC:dos") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a neuronal dense core vesicle.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0099014") +AnnotationAssertion(rdfs:label "neuronal dense core vesicle organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (presynapse assembly) + +AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:bf") Annotation( "GOC:dos") Annotation( "PMID:24449494") "The aggregation, arrangement and bonding together of a set of components to form a presynapse.") +AnnotationAssertion(Annotation( "GOC:mah") "presynapse biogenesis") +AnnotationAssertion(Annotation( "PMID:24449494") "presynaptic terminal assembly") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0099054") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "presynapse assembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (postsynapse assembly) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:dos") Annotation( "GOCL:PARL") "The aggregation, arrangement and bonding together of a set of components to form a postsynapse.") +AnnotationAssertion(Annotation( "GOC:mah") "postsynapse biogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0099068") +AnnotationAssertion(rdfs:label "postsynapse assembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (regulation of postsynaptic membrane neurotransmitter receptor levels) + +AnnotationAssertion(Annotation( "GOC:dos") "Any process that regulates the the local concentration of neurotransmitter receptor at the postsynaptic membrane.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0099072") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "regulation of postsynaptic membrane neurotransmitter receptor levels") +SubClassOf( ) + # Class: (supramolecular complex) AnnotationAssertion(Annotation( "GOC:dos") "A cellular component that consists of an indeterminate number of proteins or macromolecular complexes, organized into a regular, higher-order structure such as a polymer, sheet, network or a fiber.") @@ -40960,14 +112750,322 @@ AnnotationAssertion(Annotation( "cellular_component") AnnotationAssertion( "GO:0099081") AnnotationAssertion(rdfs:label "supramolecular polymer") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (retrograde trans-synaptic signaling by neuropeptide) + +AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:bf") Annotation( "GOC:dos") Annotation( "PMID:19448629") "Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by a neuropeptide.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0099082") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "retrograde trans-synaptic signaling by neuropeptide") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (retrograde trans-synaptic signaling by neuropeptide, modulating synaptic transmission) + +AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:bf") Annotation( "GOC:dos") Annotation( "PMID:19448629") "Modulation of synaptic transmittion by cell-cell signaling across the synaptic cleft from postsynapse to presynapse, mediated by a neuropeptide.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0099083") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:comment "Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.") +AnnotationAssertion(rdfs:label "retrograde trans-synaptic signaling by neuropeptide, modulating synaptic transmission") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (microtubule polymerization based movement) + +AnnotationAssertion(Annotation( "GOC:cjm") Annotation( "ISBN:0815316194") "The movement of a cellular component as a result of microtubule polymerization.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0099098") +AnnotationAssertion(rdfs:label "microtubule polymerization based movement") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (microtubule-based transport) + +AnnotationAssertion(Annotation( "GOC:cjm") Annotation( "ISBN:0815316194") "A microtubule-based process that results in the transport of organelles, other microtubules, or other cellular components. Examples include motor-driven movement along microtubules and movement driven by polymerization or depolymerization of microtubules.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0099111") +AnnotationAssertion(rdfs:label "microtubule-based transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (microtubule polymerization based protein transport) + +AnnotationAssertion(Annotation( "GOC:dos") Annotation( "GOC:vw") Annotation( "PMID:11018050") "The transport of a protein driven by polymerization of a microtubule to which it is attached.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0099112") +AnnotationAssertion(rdfs:label "microtubule polymerization based protein transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (microtubule-based protein transport) + +AnnotationAssertion(Annotation( "GOC:vw") "A microtubule-based process that results in the transport of proteins.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0099118") +AnnotationAssertion(rdfs:label "microtubule-based protein transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (somato-dendritic dopamine secretion) + +AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:bf") Annotation( "PMID:21576241") "The regulated release of dopamine from the somatodendritic compartment (cell body or dendrites) of a neuron.") +AnnotationAssertion(Annotation( "PMID:21576241") "STD DA release") +AnnotationAssertion(Annotation( "PMID:21576241") "STD dopamine release") +AnnotationAssertion(Annotation( "PMID:21576241") "somatodendritic dopamine release") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0099123") +AnnotationAssertion(rdfs:label "somato-dendritic dopamine secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (axonal dopamine secretion) + +AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:bf") Annotation( "PMID:21576241") "The regulated release of dopamine from an axon.") +AnnotationAssertion(Annotation( "PMID:21576241") "axonal DA release") +AnnotationAssertion(Annotation( "PMID:21576241") "axonal dopamine release") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0099124") +AnnotationAssertion(rdfs:label "axonal dopamine secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (presynaptic actin cytoskeleton organization) + +AnnotationAssertion(Annotation( "GOC:dos") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins in the presynaptic actin cytoskeleton.") +AnnotationAssertion( "dos") +AnnotationAssertion( "2017-06-09T18:34:19Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0099140") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "presynaptic actin cytoskeleton organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (presynaptic actin cytoskeleton) + +AnnotationAssertion(Annotation( "GOC:dos") "The actin cytoskeleton that is part of a presynapse.") +AnnotationAssertion( "dos") +AnnotationAssertion( "2017-06-09T18:36:19Z") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0099143") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "presynaptic actin cytoskeleton") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of exocytic insertion of neurotransmitter receptor to postsynaptic membrane) + +AnnotationAssertion(Annotation( "GOC:dos") "Any process that modulates the frequency, rate or extent of exocytic fusion of neurotransmitter receptor containing vesicles into the postsynaptic membrane.") +AnnotationAssertion( "dos") +AnnotationAssertion( "2017-06-09T18:49:26Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0099145") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "regulation of exocytic insertion of neurotransmitter receptor to postsynaptic membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (cell-cell signaling via exosome) + +AnnotationAssertion(Annotation( "GOC:dos") Annotation( "PMID:19837038") "Cell-cell signaling in which the ligand is carried between cells by an exosome.") +AnnotationAssertion( "dos") +AnnotationAssertion( "2017-07-05T16:40:45Z") +AnnotationAssertion( "exosome mediated") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0099156") +AnnotationAssertion(rdfs:label "cell-cell signaling via exosome") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (trans-synaptic signaling via exosome) + +AnnotationAssertion(Annotation( "GOC:dos") Annotation( "PMID:19837038") "Transynaptic signaling in which the ligand is carried across the synapse by an exosome.") +AnnotationAssertion( "dos") +AnnotationAssertion( "2017-07-05T16:49:44Z") +AnnotationAssertion( "exosome mediated transynaptic signalling") +AnnotationAssertion( "trans-synaptic signalling via exosome") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0099157") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "trans-synaptic signaling via exosome") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (postsynaptic intermediate filament cytoskeleton) + +AnnotationAssertion(Annotation( "GOC:dos") Annotation( "PMID:25869803") "The intermediate filament cytoskeleton that is part of a postsynapse.") +AnnotationAssertion( "dos") +AnnotationAssertion( "2017-08-28T15:26:08Z") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0099160") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "postsynaptic intermediate filament cytoskeleton") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (postsynaptic modulation of chemical synaptic transmission) + +AnnotationAssertion(Annotation( "GOC:dos") "Any process, acting in the postsynapse that results in modulation of chemical synaptic transmission.") +AnnotationAssertion( "dos") +AnnotationAssertion( "2017-09-11T17:09:17Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0099170") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "postsynaptic modulation of chemical synaptic transmission") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (presynaptic modulation of chemical synaptic transmission) + +AnnotationAssertion(Annotation( "GOC:dos") "Any process, acting in the presynapse that results in modulation of chemical synaptic transmission.") +AnnotationAssertion( "dos") +AnnotationAssertion( "2017-09-11T17:09:31Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0099171") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "presynaptic modulation of chemical synaptic transmission") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (presynapse organization) + +AnnotationAssertion(Annotation( "GOC:dos") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a presynapse.") +AnnotationAssertion( "presynapse development") +AnnotationAssertion( "presynapse organisation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:BHF") "presynapse morphogenesis") +AnnotationAssertion(Annotation( "GOC:mah") "presynapse organization and biogenesis") +AnnotationAssertion( "GO:0099172") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "presynapse organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (postsynapse organization) + +AnnotationAssertion(Annotation( "GOC:dos") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a postsynapse.") +AnnotationAssertion( "postsynapse development") +AnnotationAssertion( "postsynapse organisation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:BHF") "postsynapse morphogenesis") +AnnotationAssertion(Annotation( "GOC:mah") "postsynapse organization and biogenesis") +AnnotationAssertion( "GO:0099173") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "postsynapse organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (regulation of presynapse organization) + +AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the physical form of a presynapse.") +AnnotationAssertion(Annotation( "GOC:mah") "regulation of presynapse organisation") +AnnotationAssertion( "regulation of presynapse structure") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:mah") "regulation of presynapse organization and biogenesis") +AnnotationAssertion( "GO:0099174") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "regulation of presynapse organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (regulation of postsynapse organization) + +AnnotationAssertion(Annotation( "GOC:ai") Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that modulates the physical form of a postsynapse.") +AnnotationAssertion(Annotation( "GOC:mah") "regulation of postsynapse organisation") +AnnotationAssertion( "regulation of postsynapse structure") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:mah") "regulation of postsynapse organization and biogenesis") +AnnotationAssertion( "GO:0099175") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "regulation of postsynapse organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (regulation of trans-synaptic signaling) + +AnnotationAssertion(Annotation( "GOC:dos") "Any process that modulates the frequency, rate or extent of trans-synaptic signaling.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0099177") +AnnotationAssertion(rdfs:label "regulation of trans-synaptic signaling") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (presynaptic intermediate filament cytoskeleton) + +AnnotationAssertion(Annotation( "GOC:dos") "The intermediate filament cytoskeleton that is part of a presynapse.") +AnnotationAssertion( "dos") +AnnotationAssertion( "2017-12-01T18:10:21Z") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0099182") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "presynaptic intermediate filament cytoskeleton") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (postsynaptic intermediate filament cytoskeleton organization) + +AnnotationAssertion(Annotation( "GOC:dos") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprised of intermediate filament and their associated proteins in the postsynaptic cytoskeleton.") +AnnotationAssertion( "dos") +AnnotationAssertion( "2017-12-20T13:47:30Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0099185") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "postsynaptic intermediate filament cytoskeleton organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (presynaptic cytoskeleton organization) + +AnnotationAssertion(Annotation( "GOC:dos") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures and their associated proteins in the presynaptic cytoskeleton.") +AnnotationAssertion( "dos") +AnnotationAssertion( "2017-12-20T15:05:34Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0099187") +AnnotationAssertion(rdfs:label "presynaptic cytoskeleton organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (postsynaptic cytoskeleton organization) + +AnnotationAssertion(Annotation( "GOC:dos") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising cytoskeletal filaments and their associated proteins in the postsynaptic cytoskeleton.") +AnnotationAssertion( "dos") +AnnotationAssertion( "2017-12-20T15:06:57Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0099188") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "postsynaptic cytoskeleton organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (vesicle fusion to plasma membrane) AnnotationAssertion(Annotation( "GOC:aruk") Annotation( "GOC:bc") Annotation( "ISBN:0071120009") Annotation( "PMID:18618940") "Fusion of the membrane of a vesicle with the plasma membrane, thereby releasing its contents into the extracellular space.") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0099500") AnnotationAssertion(rdfs:label "vesicle fusion to plasma membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (exocytic vesicle membrane) + +AnnotationAssertion(Annotation( "GOC:dos") "The lipid bilayer surrounding an exocytic vesicle.") +AnnotationAssertion( "secretory vesicle membrane") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0099501") +AnnotationAssertion(rdfs:label "exocytic vesicle membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (secretory vesicle) + +AnnotationAssertion(Annotation( "GOC:dos") "A cytoplasmic, membrane bound vesicle that is capable of fusing to the plasma membrane to release its contents into the extracellular space.") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0099503") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "secretory vesicle") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (synaptic vesicle cycle) + +AnnotationAssertion(Annotation( "GOC:aruk") Annotation( "GOC:bc") Annotation( "PMID:15217342") "A biological process in which synaptic vesicles are loaded with neurotransmitters, move to the active zone, exocytose and are then recycled via endocytosis, ultimately leading to reloading with neurotransmitters.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0099504") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "synaptic vesicle cycle") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) # Class: (supramolecular fiber) @@ -40977,6 +113075,7 @@ AnnotationAssertion( "fibril") AnnotationAssertion( "GO:0099512") AnnotationAssertion(rdfs:label "supramolecular fiber") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf( ) # Class: (polymeric cytoskeletal fiber) @@ -40985,9 +113084,115 @@ AnnotationAssertion(Annotation( "cellular_component") AnnotationAssertion( "GO:0099513") AnnotationAssertion(rdfs:label "polymeric cytoskeletal fiber") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (actin filament-based transport) + +AnnotationAssertion(Annotation( "GOC:dos") Annotation( "GOC:dph") Annotation( "GOC:mah") Annotation( "GOC:tb") "The transport of organelles or other particles from one location in the cell to another along actin filaments.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2009-05-27T10:56:08Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0099515") +AnnotationAssertion(rdfs:label "actin filament-based transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (vesicle cytoskeletal trafficking) + +AnnotationAssertion(Annotation( "GOC:ecd") Annotation( "GOC:rl") "The directed movement of a vesicle along a cytoskeletal fiber such as a microtubule or and actin filament, mediated by motor proteins.") +AnnotationAssertion(Annotation( "GOC:rl") "cytoskeletal fiber-based vesicle localization") +AnnotationAssertion( "vesicle cytoskeletal transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0099518") +AnnotationAssertion(rdfs:label "vesicle cytoskeletal trafficking") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (dense core granule cytoskeletal transport) + +AnnotationAssertion(Annotation( "GOC:kmv") Annotation( "PMID:23358451") "The directed movement of dense core granules along cytoskeletal fibers, such as microtubules or actin filaments.") +AnnotationAssertion( "dense core vesicle cytoskeletal trafficking") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0099519") +AnnotationAssertion(rdfs:label "dense core granule cytoskeletal transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (cytosolic region) + +AnnotationAssertion(Annotation( "GOC:dos") "Any (proper) part of the cytosol of a single cell of sufficient size to still be considered cytosol.") +AnnotationAssertion( "region of cytosol") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0099522") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "cytosolic region") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (presynaptic cytosol) + +AnnotationAssertion(Annotation( "GOC:dos") "The region of the cytosol consisting of all cytosol that is part of the presynapse.") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0099523") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "presynaptic cytosol") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (postsynaptic cytosol) + +AnnotationAssertion(Annotation( "GOC:dos") "The region of the cytosol consisting of all cytosol that is part of the postsynapse.") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0099524") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "postsynaptic cytosol") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (G protein-coupled neurotransmitter receptor activity) + +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:fj") Annotation( "GOC:mah") "Combining with a neurotransmitter and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.") +AnnotationAssertion( "G-protein coupled neurotransmitter receptor activity") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0099528") +AnnotationAssertion(rdfs:label "G protein-coupled neurotransmitter receptor activity") +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential) + +AnnotationAssertion(Annotation( "GOC:dos") "Neurotransmitter receptor activity occurring in the postsynaptic membrane that is involved in regulating postsynaptic membrane potential, either directly (ionotropic receptors) or indirectly (e.g. via GPCR activation of an ion channel).") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0099529") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (G protein-coupled receptor activity involved in regulation of postsynaptic membrane potential) + +AnnotationAssertion(Annotation( "GOC:dos") "A G protein-coupled receptor activity occurring in the postsynaptic membrane that is part of a GPCR signaling pathway that positively regulates ion channel activity in the postsynaptic membrane.") +AnnotationAssertion( "G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0099530") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "G protein-coupled receptor activity involved in regulation of postsynaptic membrane potential") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (presynaptic process involved in chemical synaptic transmission) + +AnnotationAssertion(Annotation( "GOC:dos") "The pathway leading to secretion of a neurotransmitter from the presynapse as part of synaptic transmission.") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0099531") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "presynaptic process involved in chemical synaptic transmission") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + # Class: (synaptic signaling) AnnotationAssertion(Annotation( "GOC:dos") "Cell-cell signaling to, from or within a synapse.") @@ -40996,6 +113201,7 @@ AnnotationAssertion( ) AnnotationAssertion( ) AnnotationAssertion(rdfs:label "synaptic signaling") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectAllValuesFrom( )) @@ -41509,44 +113715,48 @@ AnnotationAssertion( "positive regulation of cardiac muscle myoblast proliferation") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -# Class: (pharynx morphogenesis) +# Class: (nematode pharynx morphogenesis) -AnnotationAssertion(Annotation( "GOC:rz") Annotation( "PMID:20805556") "The process in which the anatomical structures of the pharynx are generated and organized.") +AnnotationAssertion(Annotation( "GOC:rz") Annotation( "PMID:20805556") "The process in which the anatomical structures of the nematode pharynx are generated and organized.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/18285"^^xsd:anyURI) AnnotationAssertion( "kmv") AnnotationAssertion( "2017-07-24T20:51:28Z") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0110040") -AnnotationAssertion(rdfs:label "pharynx morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +AnnotationAssertion(rdfs:label "nematode pharynx morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -# Class: (regulation of pharynx morphogenesis) +# Class: (regulation of nematode pharynx morphogenesis) -AnnotationAssertion(Annotation( "GOC:rz") Annotation( "PMID:20805556") "Any process that modulates the frequency, rate or extent of pharynx morphogenesis, the process in which the anatomical structure of the pharynx is generated and organized.") +AnnotationAssertion(Annotation( "GOC:rz") Annotation( "PMID:20805556") "Any process that modulates the frequency, rate or extent of nematode pharynx morphogenesis, the process in which the anatomical structure of the pharynx is generated and organized.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/18285"^^xsd:anyURI) AnnotationAssertion( "kmv") AnnotationAssertion( "2017-07-24T21:00:20Z") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0110041") -AnnotationAssertion(rdfs:label "regulation of pharynx morphogenesis") +AnnotationAssertion(rdfs:label "regulation of nematode pharynx morphogenesis") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -# Class: (negative regulation of pharynx morphogenesis) +# Class: (negative regulation of nematode pharynx morphogenesis) -AnnotationAssertion(Annotation( "GOC:rz") Annotation( "PMID:20805556") "Any process that stops, prevents, or reduces the frequency, rate or extent of pharynx morphogenesis.") +AnnotationAssertion(Annotation( "GOC:rz") Annotation( "PMID:20805556") "Any process that stops, prevents, or reduces the frequency, rate or extent of nematode pharynx morphogenesis.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/18285"^^xsd:anyURI) AnnotationAssertion( "kmv") AnnotationAssertion( "2017-07-24T21:05:08Z") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0110042") -AnnotationAssertion(rdfs:label "negative regulation of pharynx morphogenesis") +AnnotationAssertion(rdfs:label "negative regulation of nematode pharynx morphogenesis") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) -# Class: (positive regulation of pharynx morphogenesis) +# Class: (positive regulation of nematode pharynx morphogenesis) -AnnotationAssertion(Annotation( "GOC:rz") Annotation( "PMID:20805556") "Any process that activates or increases the frequency, rate or extent of pharynx morphogenesis.") +AnnotationAssertion(Annotation( "GOC:rz") Annotation( "PMID:20805556") "Any process that activates or increases the frequency, rate or extent of nematode pharynx morphogenesis.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/18285"^^xsd:anyURI) AnnotationAssertion( "kmv") AnnotationAssertion( "2017-07-24T21:09:48Z") AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0110043") -AnnotationAssertion(rdfs:label "positive regulation of pharynx morphogenesis") +AnnotationAssertion(rdfs:label "positive regulation of nematode pharynx morphogenesis") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (regulation of actin filament organization) @@ -41869,6 +114079,50 @@ SubClassOf( ) SubClassOf( ) +# Class: (regulation of glutamatergic neuron differentiation) + +AnnotationAssertion(Annotation( "PMID:24030726") "Any process that modulates the frequency, rate or extent of glutamatergic neuron differentiation.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/13107"^^xsd:anyURI) +AnnotationAssertion( "krc") +AnnotationAssertion( "2017-03-01T16:10:27Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0120006") +AnnotationAssertion(rdfs:label "regulation of glutamatergic neuron differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of glutamatergic neuron differentiation) + +AnnotationAssertion(Annotation( "PMID:24030726") "Any process that stops, prevents or reduces the frequency, rate or extent of glutamatergic neuron differentiation.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/13107"^^xsd:anyURI) +AnnotationAssertion( "krc") +AnnotationAssertion( "2017-03-01T16:25:50Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0120007") +AnnotationAssertion(rdfs:label "negative regulation of glutamatergic neuron differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of glutamatergic neuron differentiation) + +AnnotationAssertion(Annotation( "PMID:24030726") "Any process that activates or increases the frequency, rate or extent of glutamatergic neuron differentiation.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/13107"^^xsd:anyURI) +AnnotationAssertion( "krc") +AnnotationAssertion( "2017-03-01T16:35:45Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0120008") +AnnotationAssertion(rdfs:label "positive regulation of glutamatergic neuron differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (somatostatin binding) + +AnnotationAssertion(Annotation( "GOC:cvs") Annotation( "PMID:20472043") "Binding to somatostatin, a polypeptide hormone involved in regulating pancreatic alpha and pancreatic beta cells and controlling growth hormone secretion as well as many other functions. Somatostatin is produced by several cell types including pancreatic delta cells. There are several different mature forms of somatostatin.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/13143"^^xsd:anyURI) +AnnotationAssertion( "krc") +AnnotationAssertion( "2017-03-17T14:54:21Z") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:0120023") +AnnotationAssertion(rdfs:label "somatostatin binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (plasma membrane bounded cell projection) AnnotationAssertion(Annotation( "GOC:krc") "A prolongation or process extending from a cell and that is bounded by plasma membrane, e.g. a cilium, lamellipodium, or axon.") @@ -41878,6 +114132,484 @@ AnnotationAssertion( AnnotationAssertion( "cellular_component") AnnotationAssertion( "GO:0120025") AnnotationAssertion(rdfs:label "plasma membrane bounded cell projection") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (plasma membrane bounded cell projection assembly) + +AnnotationAssertion(Annotation( "GOC:krc") "Formation of a prolongation or process extending and that is bounded by plasma membrane, e.g. a cilium, lamellipodium, or axon.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/13298"^^xsd:anyURI) +AnnotationAssertion( "krc") +AnnotationAssertion( "2017-04-24T23:56:08Z") +AnnotationAssertion(Annotation( "GOC:krc") Annotation( "GOC:rjd") Annotation( "PMID:10328951") Annotation( "PMID:9096956") "eupodium") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0120031") +AnnotationAssertion(rdfs:label "plasma membrane bounded cell projection assembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of plasma membrane bounded cell projection assembly) + +AnnotationAssertion(Annotation( "GOC:krc") "Any process that modulates the rate, frequency, or extent of plasma membrane bounded cell projection assembly.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/13298"^^xsd:anyURI) +AnnotationAssertion( "krc") +AnnotationAssertion( "2017-04-26T04:27:04Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0120032") +AnnotationAssertion(rdfs:label "regulation of plasma membrane bounded cell projection assembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of plasma membrane bounded cell projection assembly) + +AnnotationAssertion(Annotation( "GOC:krc") "Any process that stops, prevents or reduces the frequency, rate or extent of plasma membrane bounded cell projection assembly.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/13298"^^xsd:anyURI) +AnnotationAssertion( "krc") +AnnotationAssertion( "2017-04-26T04:34:31Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0120033") +AnnotationAssertion(rdfs:label "negative regulation of plasma membrane bounded cell projection assembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of plasma membrane bounded cell projection assembly) + +AnnotationAssertion(Annotation( "GOC:krc") "Any process that activates or increases the frequency, rate or extent of plasma membrane bounded cell projection assembly.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/13298"^^xsd:anyURI) +AnnotationAssertion( "krc") +AnnotationAssertion( "2017-04-26T04:34:45Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0120034") +AnnotationAssertion(rdfs:label "positive regulation of plasma membrane bounded cell projection assembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (regulation of plasma membrane bounded cell projection organization) + +AnnotationAssertion(Annotation( "GOC:krc") "Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of plasma membrane bounded cell projections.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/13298"^^xsd:anyURI) +AnnotationAssertion( "krc") +AnnotationAssertion( "2017-04-26T16:02:06Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0120035") +AnnotationAssertion(rdfs:label "regulation of plasma membrane bounded cell projection organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (plasma membrane bounded cell projection organization) + +AnnotationAssertion(Annotation( "GOC:krc") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a plasma membrane bounded prolongation or process extending from a cell, e.g. a cilium or axon.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/13298"^^xsd:anyURI) +AnnotationAssertion( "krc") +AnnotationAssertion( "2017-04-26T16:07:02Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0120036") +AnnotationAssertion(rdfs:label "plasma membrane bounded cell projection organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (plasma membrane bounded cell projection morphogenesis) + +AnnotationAssertion(Annotation( "GOC:krc") "The process in which the anatomical structures of a plasma membrane bounded cell projection are generated and organized.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/13298"^^xsd:anyURI) +AnnotationAssertion( "krc") +AnnotationAssertion( "2017-04-28T23:39:37Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0120039") +AnnotationAssertion(rdfs:label "plasma membrane bounded cell projection morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (neuron projection cytoplasm) + +AnnotationAssertion(Annotation( "GOC:ha") "All of the contents of a plasma membrane bounded neuron projection, excluding the plasma membrane surrounding the projection.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/14472"^^xsd:anyURI) +AnnotationAssertion( "krc") +AnnotationAssertion( "2017-11-01T18:58:12Z") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0120111") +AnnotationAssertion(rdfs:label "neuron projection cytoplasm") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (glucagon processing) + +AnnotationAssertion(Annotation( "PMID:28719828") "The formation of mature glucagon by proteolysis of the precursor proglucagon.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/14505"^^xsd:anyURI) +AnnotationAssertion( "krc") +AnnotationAssertion( "2017-11-08T19:31:42Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0120116") +AnnotationAssertion(rdfs:label "glucagon processing") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (positive regulation of collagen catabolic process) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "Any process that activates or increases the frequency, rate or extent of collagen catabolism. Collagen catabolism is the proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/15720"^^xsd:anyURI) +AnnotationAssertion( "krc") +AnnotationAssertion( "2018-05-11T16:31:42Z") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "positive regulation of collagen breakdown") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "positive regulation of collagen catabolism") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "positive regulation of collagen degradation") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "up regulation of collagen catabolic process") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "up-regulation of collagen catabolic process") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "upregulation of collagen catabolic process") +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:tb") "activation of collagen catabolic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0120158") +AnnotationAssertion(rdfs:label "positive regulation of collagen catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (steroid hormone biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:krc") Annotation( "GOC:nln") "The chemical reactions and pathways resulting in the formation of any steroid hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/16000"^^xsd:anyURI) +AnnotationAssertion( "krc") +AnnotationAssertion( "2019-05-20T22:34:00Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0120178") +AnnotationAssertion(rdfs:label "steroid hormone biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of protein localization to chromatin) + +AnnotationAssertion(Annotation( "PMID:20889714") Annotation( "PMID:29899453") "Any process that stops, prevents, or reduces the frequency, rate or extent of protein localization to chromatin.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/16012"^^xsd:anyURI) +AnnotationAssertion( "krc") +AnnotationAssertion( "2018-07-14T00:19:32Z") +AnnotationAssertion(Annotation( "GOC:krc") "negative regulation of protein localisation to chromatin") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0120186") +AnnotationAssertion(rdfs:label "negative regulation of protein localization to chromatin") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of protein localization to chromatin) + +AnnotationAssertion(Annotation( "PMID:20889714") Annotation( "PMID:29899453") "Any process that activates or increases the frequency, rate or extent of protein localization to chromatin.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/16012"^^xsd:anyURI) +AnnotationAssertion( "krc") +AnnotationAssertion( "2018-07-14T00:21:28Z") +AnnotationAssertion(Annotation( "GOC:krc") "positive regulation of protein localisation to chromatin") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0120187") +AnnotationAssertion(rdfs:label "positive regulation of protein localization to chromatin") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of bile acid secretion) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_miRNA") Annotation( "GOC:rph") Annotation( "PMID:22767443") "Any process that modulates the frequency, rate or extent of the controlled release of bile acid from a cell or a tissue.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/16040"^^xsd:anyURI) +AnnotationAssertion( "krc") +AnnotationAssertion( "2018-07-16T22:28:58Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0120188") +AnnotationAssertion(rdfs:label "regulation of bile acid secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of bile acid secretion) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_miRNA") Annotation( "GOC:rph") Annotation( "PMID:22767443") "Any process that activates or increases the frequency, rate or extent of the controlled release of bile acid from a cell or a tissue.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/16040"^^xsd:anyURI) +AnnotationAssertion( "krc") +AnnotationAssertion( "2018-07-16T22:36:17Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0120189") +AnnotationAssertion(rdfs:label "positive regulation of bile acid secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of bile acid secretion) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_miRNA") Annotation( "GOC:rph") Annotation( "PMID:22767443") "Any process that stops, prevents or reduces the frequency, rate or extent of the controlled release of bile acid from a cell or a tissue.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/16040"^^xsd:anyURI) +AnnotationAssertion( "krc") +AnnotationAssertion( "2018-07-16T22:38:34Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0120190") +AnnotationAssertion(rdfs:label "negative regulation of bile acid secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (tight junction assembly) + +AnnotationAssertion(Annotation( "GOC:rl") "A cellular process that results in the aggregation, arrangement and bonding together of a set of components to form a tight junction. A tight junction seals cells together in an epithelium in a way that prevents even small molecules from leaking from one side of the sheet to the other.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/16187"^^xsd:anyURI) +AnnotationAssertion( "krc") +AnnotationAssertion( "2018-08-14T22:48:05Z") +AnnotationAssertion(Annotation( "GOC:rl") "occluding cell junction assembly") +AnnotationAssertion(Annotation( "GOC:rl") "occluding junction assembly") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0120192") +AnnotationAssertion(rdfs:label "tight junction assembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (tight junction organization) + +AnnotationAssertion(Annotation( "GOC:krc") Annotation( "GOC:rl") "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a tight junction. A tight junction seals cells together in an epithelium in a way that prevents even small molecules from leaking from one side of the sheet to the other.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/16187"^^xsd:anyURI) +AnnotationAssertion( "krc") +AnnotationAssertion( "2018-08-14T23:05:40Z") +AnnotationAssertion(Annotation( "GOC:rl") "occluding cell junction organization") +AnnotationAssertion( "occluding junction organization") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0120193") +AnnotationAssertion(rdfs:label "tight junction organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (cone photoreceptor outer segment) + +AnnotationAssertion(Annotation( "GOC:krc") Annotation( "GOC:pde") Annotation( "PMID:19501669") Annotation( "PMID:26574505") Annotation( "PMID:6771304") "The outer segment of a vertebrate cone photoreceptor that contains membrane discs that are contiguous with the ciliary membrane and containing opsin photoreceptor proteins.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/17217"^^xsd:anyURI) +AnnotationAssertion( "krc") +AnnotationAssertion( "2019-05-07T22:23:28Z") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0120199") +AnnotationAssertion(rdfs:label "cone photoreceptor outer segment") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (rod photoreceptor outer segment) + +AnnotationAssertion(Annotation( "GOC:krc") Annotation( "GOC:pde") Annotation( "PMID:19501669") Annotation( "PMID:26574505") Annotation( "PMID:6771304") "The outer segment of a vertebrate rod photoreceptor that contains sealed membrane discs that are not connected to the ciliary membrane and containing rhodopsin photoreceptor proteins.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/17217"^^xsd:anyURI) +AnnotationAssertion( "krc") +AnnotationAssertion( "2019-05-07T22:47:20Z") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:0120200") +AnnotationAssertion(rdfs:label "rod photoreceptor outer segment") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of blastocyst development) + +AnnotationAssertion(Annotation( "GOC:krc") Annotation( "PMID:29593216") "Any process that modulates the frequency, rate or extent of blastocyst development.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/18871"^^xsd:anyURI) +AnnotationAssertion( "krc") +AnnotationAssertion( "2020-02-17T19:59:20Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0120222") +AnnotationAssertion(rdfs:label "regulation of blastocyst development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (larynx morphogenesis) + +AnnotationAssertion(Annotation( "GOC:krc") Annotation( "PMID:28177282") "The process in which the larynx is generated and organized. The larynx is a continuation of the pharynx that is involved in breathing, sound production, and protecting the trachea against food aspiration.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/18924"^^xsd:anyURI) +AnnotationAssertion( "krc") +AnnotationAssertion( "2020-02-22T01:42:04Z") +AnnotationAssertion(Annotation( "GOC:krc") Annotation( "PMID:28177282") "laryngeal morphogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0120223") +AnnotationAssertion(rdfs:label "larynx morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (larynx development) + +AnnotationAssertion(Annotation( "GOC:krc") Annotation( "PMID:28177282") "The biological process whose specific outcome is the progression of a larynx from an initial condition to its mature state. This process begins with the formation of the larynx and ends with the mature structure. A larynx is a continuation of the pharynx that is involved in breathing, sound production, and protecting the trachea against food aspiration.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/18924"^^xsd:anyURI) +AnnotationAssertion( "krc") +AnnotationAssertion( "2020-02-24T17:13:10Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0120224") +AnnotationAssertion(rdfs:label "larynx development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (protein localization to motile cilium) + +AnnotationAssertion(Annotation( "GOC:krc") Annotation( "PMID:27486780") "A process in which a protein is transported to, or maintained in, a location within a motile cilium.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/19588"^^xsd:anyURI) +AnnotationAssertion( "krc") +AnnotationAssertion( "2020-06-05T23:43:04Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "protein localization to nonmotile primary cilium") +AnnotationAssertion( "GO:0120229") +AnnotationAssertion(rdfs:label "protein localization to motile cilium") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (hydrocarbon biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:krc") Annotation( "Wikipedia:Hydrocarbon") "The chemical reactions and pathways resulting in the formation of a hydrocarbon, a compound consisting of carbon and hydrogen only.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/19842"^^xsd:anyURI) +AnnotationAssertion( "krc") +AnnotationAssertion( "2020-09-02T20:35:53Z") +AnnotationAssertion(Annotation( "GOC:krc") "hydrocarbon anabolism") +AnnotationAssertion(Annotation( "GOC:krc") "hydrocarbon biosynthesis") +AnnotationAssertion(Annotation( "GOC:krc") "hydrocarbon formation") +AnnotationAssertion(Annotation( "GOC:krc") "hydrocarbon synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0120251") +AnnotationAssertion(rdfs:label "hydrocarbon biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (hydrocarbon metabolic process) + +AnnotationAssertion(Annotation( "GOC:krc") Annotation( "Wikipedia:Hydrocarbon") "The chemical reactions and pathways involving a hydrocarbon, a compound consisting of carbon and hydrogen only.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/19842"^^xsd:anyURI) +AnnotationAssertion( "krc") +AnnotationAssertion( "2020-09-02T20:47:28Z") +AnnotationAssertion(Annotation( "GOC:krc") "hydrocarbon metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0120252") +AnnotationAssertion(rdfs:label "hydrocarbon metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (hydrocarbon catabolic process) + +AnnotationAssertion(Annotation( "GOC:krc") Annotation( "Wikipedia:Hydrocarbon") "The chemical reactions and pathways resulting in the breakdown of a hydrocarbon, a compound consisting of carbon and hydrogen only.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/19842"^^xsd:anyURI) +AnnotationAssertion( "krc") +AnnotationAssertion( "2020-09-02T20:58:57Z") +AnnotationAssertion(Annotation( "GOC:krc") "hydrocarbon breakdown") +AnnotationAssertion(Annotation( "GOC:krc") "hydrocarbon catabolism") +AnnotationAssertion(Annotation( "GOC:krc") "hydrocarbon degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0120253") +AnnotationAssertion(rdfs:label "hydrocarbon catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (olefinic compound metabolic process) + +AnnotationAssertion(Annotation( "GOC:krc") "The chemical reactions and pathways involving an olefinic compound, any compound which contains a carbon-carbon double bond (aka C=C).") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/19936"^^xsd:anyURI) +AnnotationAssertion( "krc") +AnnotationAssertion( "2020-09-02T23:13:44Z") +AnnotationAssertion( "alkene substituted compound metabolic process") +AnnotationAssertion( "alkene substituted compound metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0120254") +AnnotationAssertion(rdfs:label "olefinic compound metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (olefinic compound biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:krc") "The chemical reactions and pathways resulting in the formation of an olefinic compound, any compound which contains a carbon-carbon double bond (aka C=C).") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/19936"^^xsd:anyURI) +AnnotationAssertion( "krc") +AnnotationAssertion( "2020-09-02T23:30:20Z") +AnnotationAssertion(Annotation( "GOC:krc") "alkene substituted compound anabolic process") +AnnotationAssertion(Annotation( "GOC:krc") "alkene substituted compound anabolism") +AnnotationAssertion(Annotation( "GOC:krc") "alkene substituted compound biosynthesis") +AnnotationAssertion(Annotation( "GOC:krc") "alkene substituted compound biosynthetic process") +AnnotationAssertion(Annotation( "GOC:krc") "alkene substituted compound synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0120255") +AnnotationAssertion(rdfs:label "olefinic compound biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (olefinic compound catabolic process) + +AnnotationAssertion(Annotation( "GOC:krc") "The chemical reactions and pathways resulting in the breakdown of an olefinic compound, any compound which contains a carbon-carbon double bond (aka C=C).") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/19936"^^xsd:anyURI) +AnnotationAssertion( "krc") +AnnotationAssertion( "2020-09-02T23:30:41Z") +AnnotationAssertion(Annotation( "GOC:krc") "alkene substituted compound breakdown") +AnnotationAssertion(Annotation( "GOC:krc") "alkene substituted compound catabolic process") +AnnotationAssertion(Annotation( "GOC:krc") "alkene substituted compound catabolism") +AnnotationAssertion(Annotation( "GOC:krc") "alkene substituted compound degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0120256") +AnnotationAssertion(rdfs:label "olefinic compound catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (cerebral blood circulation) + +AnnotationAssertion(Annotation( "GOC:krc") Annotation( "PMID:25397684") "The flow of blood through the network of arteries and veins supplying the cerebrum, enabling the transport of nutrients to the tissues and the removal of waste products.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/20107"^^xsd:anyURI) +AnnotationAssertion( "krc") +AnnotationAssertion( "2020-10-20T19:13:51Z") +AnnotationAssertion( "cerebrum blood circulation") +AnnotationAssertion( "telencephelon blood circulation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0120275") +AnnotationAssertion(rdfs:label "cerebral blood circulation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of cerebral blood circulation) + +AnnotationAssertion(Annotation( "GOC:krc") Annotation( "PMID:25397684") "Any process that modulates the frequency, rate or extent of cerebral blood circulation.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/20107"^^xsd:anyURI) +AnnotationAssertion( "krc") +AnnotationAssertion( "2020-10-21T06:52:22Z") +AnnotationAssertion( "regulation of cerebrum blood circulation") +AnnotationAssertion( "regulation of telencephalon blood circulation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0120276") +AnnotationAssertion(rdfs:label "regulation of cerebral blood circulation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of cerebral blood circulation) + +AnnotationAssertion(Annotation( "GOC:krc") Annotation( "PMID:25397684") "Any process that activates or increases the frequency, rate or extent of cerebral blood circulation.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/20107"^^xsd:anyURI) +AnnotationAssertion( "krc") +AnnotationAssertion( "2020-10-21T06:55:42Z") +AnnotationAssertion( "positive regulation of cerebrum blood circulation") +AnnotationAssertion( "positive regulation of telencephalon blood circulation") +AnnotationAssertion( "up regulation of cerebral blood circulation") +AnnotationAssertion( "up-regulation of cerebral blood circulation") +AnnotationAssertion( "upregulation of cerebral blood circulation") +AnnotationAssertion( "activation of cerebral blood circulation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0120277") +AnnotationAssertion(rdfs:label "positive regulation of cerebral blood circulation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of cerebral blood circulation) + +AnnotationAssertion(Annotation( "GOC:krc") Annotation( "PMID:25397684") "Any process that stops, prevents or reduces the frequency, rate or extent of cerebral blood circulation.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/20107"^^xsd:anyURI) +AnnotationAssertion( "krc") +AnnotationAssertion( "2020-10-21T07:02:05Z") +AnnotationAssertion( "down regulation of cerebral blood circulation") +AnnotationAssertion( "down-regulation of cerebral blood circulation") +AnnotationAssertion( "downregulation of cerebral blood circulation") +AnnotationAssertion( "negative regulation of cerebrum blood circulation") +AnnotationAssertion( "negative regulation of telencephalon blood circulation") +AnnotationAssertion( "inhibition of cerebral blood circulation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0120278") +AnnotationAssertion(rdfs:label "negative regulation of cerebral blood circulation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of pigmentation) + +AnnotationAssertion(Annotation( "GOC:krc") "Any process that modulates the frequency, rate or extent of the deposition or modulates the distribution of coloring matter in an organism.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/20524"^^xsd:anyURI) +AnnotationAssertion( "krc") +AnnotationAssertion( "2021-02-09T19:37:35Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0120305") +AnnotationAssertion(rdfs:label "regulation of pigmentation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (sperm flagellum assembly) + +AnnotationAssertion(Annotation( "GOC:krc") Annotation( "PMID:32791035") "The assembly and organization of the sperm flagellum, the microtubule-based axoneme and associated structures that are part of a sperm flagellum (or cilium).") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/21361"^^xsd:anyURI) +AnnotationAssertion( "krc") +AnnotationAssertion( "2021-04-29T01:27:27Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0120316") +AnnotationAssertion(rdfs:label "sperm flagellum assembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (endothelial tube formation) + +AnnotationAssertion(Annotation( "GOC:sl") Annotation( "PMID:23239824") "The developmental process pertaining to the initial formation of an endothelial tube.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/22302"^^xsd:anyURI) +AnnotationAssertion( "krc") +AnnotationAssertion( "2022-05-25T16:17:59Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0120331") +AnnotationAssertion(rdfs:label "endothelial tube formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) # Class: (meiotic nuclear division) @@ -42325,6 +115057,7 @@ AnnotationAssertion(Annotation( "https://github.com/geneontology/go-ontology/issues/17073"^^xsd:anyURI) AnnotationAssertion( "pg") AnnotationAssertion( "2019-04-01T10:41:38Z") +AnnotationAssertion(Annotation(rdfs:label "M6PR transports activated ARSA to the lysosome") "Reactome:R-HSA-2248891") AnnotationAssertion(Annotation(rdfs:label "iRHOM2 transports ADAM17 from ER to the Golgi-network") "Reactome:R-HSA-9662747") AnnotationAssertion(Annotation(rdfs:label "iRHOM2 transports ADAM17:Zn2+ from Golgi to the plasma membrane") "Reactome:R-HSA-9662818") AnnotationAssertion( "molecular_function") @@ -42344,6 +115077,7 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:0140352") AnnotationAssertion(rdfs:label "export from cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf( ) # Class: (lipid export from cell) @@ -42858,6 +115592,39 @@ AnnotationAssertion( "craniofacial suture closure") EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +# Class: (chordate pharynx development) + +AnnotationAssertion(Annotation( "PMID:23020903") "The process whose specific outcome is the progression of cordate pharynx over time, from its formation to the mature structure.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/18285"^^xsd:anyURI) +AnnotationAssertion( "rynl") +AnnotationAssertion( "2023-08-29T21:05:28Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0160093") +AnnotationAssertion(rdfs:label "chordate pharynx development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (nematode pharynx development) + +AnnotationAssertion(Annotation( "PMID:18050503") "The process whose specific outcome is the progression of nematode pharynx over time, from its formation to the mature structure.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/18285"^^xsd:anyURI) +AnnotationAssertion( "rynl") +AnnotationAssertion( "2023-08-29T22:05:32Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0160094") +AnnotationAssertion(rdfs:label "nematode pharynx development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (insect pharynx development) + +AnnotationAssertion(Annotation( "PMID:10952900") "The process whose specific outcome is the progression of insect pharynx over time, from its formation to the mature structure.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/18285"^^xsd:anyURI) +AnnotationAssertion( "rynl") +AnnotationAssertion( "2023-08-29T22:14:25Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:0160095") +AnnotationAssertion(rdfs:label "insect pharynx development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (positive regulation of dendrite development) AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that activates or increases the frequency, rate or extent of dendrite development.") @@ -44926,8 +117693,418 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:1901160") AnnotationAssertion(rdfs:label "primary amino compound metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (primary amino compound catabolic process) + +AnnotationAssertion(Annotation( "GOC:TermGenie") "The chemical reactions and pathways resulting in the breakdown of primary amino compound.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2012-07-18T04:45:06Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "primary amino compound breakdown") +AnnotationAssertion(Annotation( "GOC:TermGenie") "primary amino compound catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "primary amino compound degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901161") +AnnotationAssertion(rdfs:label "primary amino compound catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (primary amino compound biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:TermGenie") "The chemical reactions and pathways resulting in the formation of primary amino compound.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2012-07-18T04:45:14Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "primary amino compound anabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "primary amino compound biosynthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "primary amino compound formation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "primary amino compound synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901162") +AnnotationAssertion(rdfs:label "primary amino compound biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of trophoblast cell migration) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") "Any process that modulates the frequency, rate or extent of trophoblast cell migration.") +AnnotationAssertion( "vk") +AnnotationAssertion( "2012-07-19T07:53:06Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901163") +AnnotationAssertion(rdfs:label "regulation of trophoblast cell migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of trophoblast cell migration) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") "Any process that stops, prevents or reduces the frequency, rate or extent of trophoblast cell migration.") +AnnotationAssertion( "vk") +AnnotationAssertion( "2012-07-19T07:53:28Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of trophoblast cell migration") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of trophoblast cell migration") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of trophoblast cell migration") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of trophoblast cell migration") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901164") +AnnotationAssertion(rdfs:label "negative regulation of trophoblast cell migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (positive regulation of trophoblast cell migration) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") "Any process that activates or increases the frequency, rate or extent of trophoblast cell migration.") +AnnotationAssertion( "vk") +AnnotationAssertion( "2012-07-19T07:53:35Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of trophoblast cell migration") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of trophoblast cell migration") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of trophoblast cell migration") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of trophoblast cell migration") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901165") +AnnotationAssertion(rdfs:label "positive regulation of trophoblast cell migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (neural crest cell migration involved in autonomic nervous system development) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") "Any neural crest cell migration that is involved in autonomic nervous system development.") +AnnotationAssertion( "vk") +AnnotationAssertion( "2012-07-19T08:39:56Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901166") +AnnotationAssertion(rdfs:label "neural crest cell migration involved in autonomic nervous system development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of formation of translation initiation ternary complex) + +AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that modulates the frequency, rate or extent of formation of translation initiation ternary complex.") +AnnotationAssertion( "ss") +AnnotationAssertion( "2012-07-25T02:26:58Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of translation initiation ternary complex assembly") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901190") +AnnotationAssertion(rdfs:label "regulation of formation of translation initiation ternary complex") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of formation of translation initiation ternary complex) + +AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that stops, prevents or reduces the frequency, rate or extent of formation of translation initiation ternary complex.") +AnnotationAssertion( "ss") +AnnotationAssertion( "2012-07-25T02:27:21Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of formation of translation initiation ternary complex") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of translation initiation ternary complex assembly") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of formation of translation initiation ternary complex") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of translation initiation ternary complex assembly") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of formation of translation initiation ternary complex") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of translation initiation ternary complex assembly") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of translation initiation ternary complex assembly") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of translation initiation ternary complex assembly") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of formation of translation initiation ternary complex") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901191") +AnnotationAssertion(rdfs:label "negative regulation of formation of translation initiation ternary complex") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (positive regulation of formation of translation initiation ternary complex) + +AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that activates or increases the frequency, rate or extent of formation of translation initiation ternary complex.") +AnnotationAssertion( "ss") +AnnotationAssertion( "2012-07-25T02:27:29Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of translation initiation ternary complex assembly") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of translation initiation ternary complex assembly") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of formation of translation initiation ternary complex") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of translation initiation ternary complex assembly") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of formation of translation initiation ternary complex") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of translation initiation ternary complex assembly") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of formation of translation initiation ternary complex") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of translation initiation ternary complex assembly") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of formation of translation initiation ternary complex") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901192") +AnnotationAssertion(rdfs:label "positive regulation of formation of translation initiation ternary complex") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of extracellular matrix assembly) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") "Any process that modulates the frequency, rate or extent of extracellular matrix assembly.") +AnnotationAssertion( "rl") +AnnotationAssertion( "2012-07-27T04:04:00Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901201") +AnnotationAssertion(rdfs:label "regulation of extracellular matrix assembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (negative regulation of extracellular matrix assembly) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") "Any process that stops, prevents or reduces the frequency, rate or extent of extracellular matrix assembly.") +AnnotationAssertion( "rl") +AnnotationAssertion( "2012-07-27T04:04:24Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of extracellular matrix assembly") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of extracellular matrix assembly") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of extracellular matrix assembly") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of extracellular matrix assembly") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901202") +AnnotationAssertion(rdfs:label "negative regulation of extracellular matrix assembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of extracellular matrix assembly) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") "Any process that activates or increases the frequency, rate or extent of extracellular matrix assembly.") +AnnotationAssertion( "rl") +AnnotationAssertion( "2012-07-27T04:04:32Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of extracellular matrix assembly") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of extracellular matrix assembly") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of extracellular matrix assembly") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of extracellular matrix assembly") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901203") +AnnotationAssertion(rdfs:label "positive regulation of extracellular matrix assembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (regulation of cardiac chamber formation) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") "Any process that modulates the frequency, rate or extent of cardiac chamber formation.") +AnnotationAssertion( "rl") +AnnotationAssertion( "2012-07-31T07:18:35Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of heart chamber formation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901210") +AnnotationAssertion(rdfs:label "regulation of cardiac chamber formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of cardiac chamber formation) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") "Any process that stops, prevents or reduces the frequency, rate or extent of cardiac chamber formation.") +AnnotationAssertion( "rl") +AnnotationAssertion( "2012-07-31T07:18:57Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of cardiac chamber formation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of heart chamber formation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of cardiac chamber formation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of heart chamber formation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of cardiac chamber formation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of heart chamber formation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of heart chamber formation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of heart chamber formation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of cardiac chamber formation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901211") +AnnotationAssertion(rdfs:label "negative regulation of cardiac chamber formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of cardiac chamber formation) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") "Any process that activates or increases the frequency, rate or extent of cardiac chamber formation.") +AnnotationAssertion( "rl") +AnnotationAssertion( "2012-07-31T07:19:05Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of heart chamber formation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of heart chamber formation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of cardiac chamber formation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of heart chamber formation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of cardiac chamber formation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of heart chamber formation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of cardiac chamber formation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of heart chamber formation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of cardiac chamber formation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901212") +AnnotationAssertion(rdfs:label "positive regulation of cardiac chamber formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (regulation of cardiac chamber morphogenesis) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") "Any process that modulates the frequency, rate or extent of cardiac chamber morphogenesis.") +AnnotationAssertion( "rl") +AnnotationAssertion( "2012-08-06T17:59:11Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of heart chamber morphogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901219") +AnnotationAssertion(rdfs:label "regulation of cardiac chamber morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (negative regulation of cardiac chamber morphogenesis) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") "Any process that stops, prevents or reduces the frequency, rate or extent of cardiac chamber morphogenesis.") +AnnotationAssertion( "rl") +AnnotationAssertion( "2012-08-06T17:59:34Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of cardiac chamber morphogenesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of heart chamber morphogenesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of cardiac chamber morphogenesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of heart chamber morphogenesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of cardiac chamber morphogenesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of heart chamber morphogenesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of heart chamber morphogenesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of cardiac chamber morphogenesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of heart chamber morphogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901220") +AnnotationAssertion(rdfs:label "negative regulation of cardiac chamber morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of cardiac chamber morphogenesis) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") "Any process that activates or increases the frequency, rate or extent of cardiac chamber morphogenesis.") +AnnotationAssertion( "rl") +AnnotationAssertion( "2012-08-06T17:59:42Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of heart chamber morphogenesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of cardiac chamber morphogenesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of heart chamber morphogenesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of cardiac chamber morphogenesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of heart chamber morphogenesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of cardiac chamber morphogenesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of heart chamber morphogenesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of cardiac chamber morphogenesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of heart chamber morphogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901221") +AnnotationAssertion(rdfs:label "positive regulation of cardiac chamber morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of lung ciliated cell differentiation) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") "Any process that modulates the frequency, rate or extent of lung ciliated cell differentiation.") +AnnotationAssertion( "vk") +AnnotationAssertion( "2012-08-08T08:58:34Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901246") +AnnotationAssertion(rdfs:label "regulation of lung ciliated cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of lung ciliated cell differentiation) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") "Any process that stops, prevents or reduces the frequency, rate or extent of lung ciliated cell differentiation.") +AnnotationAssertion( "vk") +AnnotationAssertion( "2012-08-08T08:58:58Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of lung ciliated cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of lung ciliated cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of lung ciliated cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of lung ciliated cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901247") +AnnotationAssertion(rdfs:label "negative regulation of lung ciliated cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (positive regulation of lung ciliated cell differentiation) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") "Any process that activates or increases the frequency, rate or extent of lung ciliated cell differentiation.") +AnnotationAssertion( "vk") +AnnotationAssertion( "2012-08-08T08:59:05Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of lung ciliated cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of lung ciliated cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of lung ciliated cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of lung ciliated cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901248") +AnnotationAssertion(rdfs:label "positive regulation of lung ciliated cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (regulation of lung goblet cell differentiation) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") "Any process that modulates the frequency, rate or extent of lung goblet cell differentiation.") +AnnotationAssertion( "vk") +AnnotationAssertion( "2012-08-08T08:59:12Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of pulmonary goblet cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901249") +AnnotationAssertion(rdfs:label "regulation of lung goblet cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of lung goblet cell differentiation) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") "Any process that stops, prevents or reduces the frequency, rate or extent of lung goblet cell differentiation.") +AnnotationAssertion( "vk") +AnnotationAssertion( "2012-08-08T08:59:36Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of lung goblet cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of pulmonary goblet cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of lung goblet cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of pulmonary goblet cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of lung goblet cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of pulmonary goblet cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of pulmonary goblet cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of lung goblet cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of pulmonary goblet cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901250") +AnnotationAssertion(rdfs:label "negative regulation of lung goblet cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (positive regulation of lung goblet cell differentiation) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") "Any process that activates or increases the frequency, rate or extent of lung goblet cell differentiation.") +AnnotationAssertion( "vk") +AnnotationAssertion( "2012-08-08T08:59:44Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of pulmonary goblet cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of lung goblet cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of pulmonary goblet cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of lung goblet cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of pulmonary goblet cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of lung goblet cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of pulmonary goblet cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of lung goblet cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of pulmonary goblet cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901251") +AnnotationAssertion(rdfs:label "positive regulation of lung goblet cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (carbohydrate derivative transport) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:bf") Annotation( "GOC:jl") "The directed movement of a carbohydrate derivative into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2012-08-16T14:51:22Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901264") +AnnotationAssertion(rdfs:label "carbohydrate derivative transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (nucleoside phosphate binding) + +AnnotationAssertion(Annotation( "GOC:TermGenie") "Binding to nucleoside phosphate.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2012-08-17T12:59:58Z") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:1901265") +AnnotationAssertion(rdfs:label "nucleoside phosphate binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (nucleoside phosphate catabolic process) + +AnnotationAssertion(Annotation( "GOC:TermGenie") "The chemical reactions and pathways resulting in the breakdown of a nucleoside phosphate.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2012-08-20T12:33:25Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "nucleoside phosphate breakdown") +AnnotationAssertion(Annotation( "GOC:TermGenie") "nucleoside phosphate catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "nucleoside phosphate degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901292") +AnnotationAssertion(rdfs:label "nucleoside phosphate catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (nucleoside phosphate biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:TermGenie") "The chemical reactions and pathways resulting in the formation of a nucleoside phosphate.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2012-08-20T12:33:45Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "nucleoside phosphate anabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "nucleoside phosphate biosynthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "nucleoside phosphate formation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "nucleoside phosphate synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901293") +AnnotationAssertion(rdfs:label "nucleoside phosphate biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (regulation of flagellated sperm motility) AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:cilia") Annotation( "GOC:krc") "Any process that modulates the frequency, rate or extent of flagellated sperm motility.") @@ -44938,8 +118115,113 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:1901317") AnnotationAssertion(rdfs:label "regulation of flagellated sperm motility") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (negative regulation of flagellated sperm motility) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:cilia") Annotation( "GOC:krc") "Any process that stops, prevents or reduces the frequency, rate or extent of flagellated sperm motility.") +AnnotationAssertion( "hjd") +AnnotationAssertion( "2012-08-22T20:50:35Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of sperm motility") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of sperm movement") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of sperm motility") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of sperm movement") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of sperm motility") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of sperm movement") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of sperm movement") +AnnotationAssertion( "negative regulation of sperm motility") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of sperm movement") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of sperm motility") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901318") +AnnotationAssertion(rdfs:label "negative regulation of flagellated sperm motility") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of odontoblast differentiation) + +AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that modulates the frequency, rate or extent of odontoblast differentiation.") +AnnotationAssertion( "hjd") +AnnotationAssertion( "2012-08-31T16:50:05Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901329") +AnnotationAssertion(rdfs:label "regulation of odontoblast differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of odontoblast differentiation) + +AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that stops, prevents or reduces the frequency, rate or extent of odontoblast differentiation.") +AnnotationAssertion( "hjd") +AnnotationAssertion( "2012-08-31T16:50:27Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of odontoblast differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of odontoblast differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of odontoblast differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of odontoblast differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901330") +AnnotationAssertion(rdfs:label "negative regulation of odontoblast differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of odontoblast differentiation) + +AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that activates or increases the frequency, rate or extent of odontoblast differentiation.") +AnnotationAssertion( "hjd") +AnnotationAssertion( "2012-08-31T16:50:35Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of odontoblast differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of odontoblast differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of odontoblast differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of odontoblast differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901331") +AnnotationAssertion(rdfs:label "positive regulation of odontoblast differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (catecholamine binding) + +AnnotationAssertion(Annotation( "GOC:TermGenie") "Binding to catecholamine.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2012-09-03T14:08:44Z") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:1901338") +AnnotationAssertion(rdfs:label "catecholamine binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of vasculature development) + +AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that modulates the frequency, rate or extent of vasculature development.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2012-09-06T09:16:15Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of vascular system development") +AnnotationAssertion( "GO:1901342") +AnnotationAssertion(rdfs:label "regulation of vasculature development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (negative regulation of vasculature development) + +AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that stops, prevents or reduces the frequency, rate or extent of vasculature development.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2012-09-06T09:17:24Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of vasculature development") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of vasculature development") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of vasculature development") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of vasculature development") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of vascular system development") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of vascular system development") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of vascular system development") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of vascular system development") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of vascular system development") +AnnotationAssertion( "GO:1901343") +AnnotationAssertion(rdfs:label "negative regulation of vasculature development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + # Class: (organic cyclic compound metabolic process) AnnotationAssertion(Annotation( "GOC:TermGenie") "The chemical reactions and pathways involving organic cyclic compound.") @@ -44949,8 +118231,22 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:1901360") AnnotationAssertion(rdfs:label "organic cyclic compound metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (organic cyclic compound catabolic process) + +AnnotationAssertion(Annotation( "GOC:TermGenie") "The chemical reactions and pathways resulting in the breakdown of organic cyclic compound.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2012-09-14T09:05:04Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "organic cyclic compound breakdown") +AnnotationAssertion(Annotation( "GOC:TermGenie") "organic cyclic compound catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "organic cyclic compound degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901361") +AnnotationAssertion(rdfs:label "organic cyclic compound catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (organic cyclic compound biosynthetic process) AnnotationAssertion(Annotation( "GOC:TermGenie") "The chemical reactions and pathways resulting in the formation of organic cyclic compound.") @@ -44963,6 +118259,7 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:1901362") AnnotationAssertion(rdfs:label "organic cyclic compound biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) @@ -44974,7 +118271,7 @@ AnnotationAssertion( AnnotationAssertion( "molecular_function") AnnotationAssertion( "GO:1901363") AnnotationAssertion(rdfs:label "heterocyclic compound binding") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) # Class: (acetate ester transport) @@ -45657,9 +118954,23 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:1901564") AnnotationAssertion(rdfs:label "organonitrogen compound metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) +# Class: (organonitrogen compound catabolic process) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:pr") "The chemical reactions and pathways resulting in the breakdown of organonitrogen compound.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2012-11-04T15:17:56Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "organonitrogen compound breakdown") +AnnotationAssertion(Annotation( "GOC:TermGenie") "organonitrogen compound catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "organonitrogen compound degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901565") +AnnotationAssertion(rdfs:label "organonitrogen compound catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (organonitrogen compound biosynthetic process) AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:pr") "The chemical reactions and pathways resulting in the formation of organonitrogen compound.") @@ -45672,9 +118983,29 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:1901566") AnnotationAssertion(rdfs:label "organonitrogen compound biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) +# Class: (organic substance catabolic process) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:pr") "The chemical reactions and pathways resulting in the breakdown of an organic substance, any molecular entity containing carbon.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2012-11-05T11:04:36Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "organic molecular entity breakdown") +AnnotationAssertion( "organic molecular entity catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "organic molecular entity catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "organic molecular entity degradation") +AnnotationAssertion( "organic substance breakdown") +AnnotationAssertion( "organic substance catabolism") +AnnotationAssertion( "organic substance degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901575") +AnnotationAssertion(rdfs:label "organic substance catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + # Class: (organic substance biosynthetic process) AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:pr") "The chemical reactions and pathways resulting in the formation of an organic substance, any molecular entity containing carbon.") @@ -45692,9 +119023,122 @@ AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:1901576") AnnotationAssertion(rdfs:label "organic substance biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) +# Class: (regulation of alkane biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that modulates the frequency, rate or extent of alkane biosynthetic process.") +AnnotationAssertion( "dhl") +AnnotationAssertion( "2012-11-05T21:54:06Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of alkane anabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of alkane biosynthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of alkane formation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of alkane synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901577") +AnnotationAssertion(rdfs:label "regulation of alkane biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of alkane biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that stops, prevents or reduces the frequency, rate or extent of alkane biosynthetic process.") +AnnotationAssertion( "dhl") +AnnotationAssertion( "2012-11-05T21:54:11Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of alkane anabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of alkane biosynthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of alkane biosynthetic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of alkane formation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of alkane synthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of alkane anabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of alkane biosynthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of alkane biosynthetic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of alkane formation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of alkane synthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of alkane anabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of alkane biosynthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of alkane biosynthetic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of alkane formation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of alkane synthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of alkane anabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of alkane biosynthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of alkane formation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of alkane synthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of alkane anabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of alkane biosynthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of alkane formation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of alkane synthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of alkane biosynthetic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901578") +AnnotationAssertion(rdfs:label "negative regulation of alkane biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of alkane biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that activates or increases the frequency, rate or extent of alkane biosynthetic process.") +AnnotationAssertion( "dhl") +AnnotationAssertion( "2012-11-05T21:54:19Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of alkane anabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of alkane biosynthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of alkane formation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of alkane synthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of alkane anabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of alkane biosynthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of alkane formation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of alkane synthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of alkane anabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of alkane biosynthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of alkane biosynthetic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of alkane formation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of alkane synthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of alkane anabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of alkane biosynthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of alkane biosynthetic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of alkane formation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of alkane synthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of alkane anabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of alkane biosynthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of alkane biosynthetic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of alkane formation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of alkane synthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of alkane biosynthetic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901579") +AnnotationAssertion(rdfs:label "positive regulation of alkane biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (dendritic microtubule) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "NIF_Subcellular:sao110773650") "Any microtubule in a dendrite, a neuron projection.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2012-11-07T14:37:30Z") +AnnotationAssertion( "NIF_Subcellular:sao110773650") +AnnotationAssertion(Annotation( "GOC:TermGenie") "microtubule of dendrite") +AnnotationAssertion(Annotation( "GOC:TermGenie") "microtubulus of dendrite") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:1901588") +AnnotationAssertion(rdfs:label "dendritic microtubule") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (axon microtubule bundle) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "NIF_Subcellular:sao707332678") "An arrangement of closely apposed microtubules running parallel to each other in the axon hillock and initial segment.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2012-11-07T15:37:12Z") +AnnotationAssertion( "NIF_Subcellular:sao707332678") +AnnotationAssertion( "axon microtubule fascicle") +AnnotationAssertion(Annotation( "GOC:TermGenie") "microtubule bundle of axon") +AnnotationAssertion(Annotation( "GOC:TermGenie") "microtubule fascicle of axon") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:1901589") +AnnotationAssertion(rdfs:label "axon microtubule bundle") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (alpha-amino acid metabolic process) AnnotationAssertion(Annotation( "GOC:TermGenie") "The chemical reactions and pathways involving an alpha-amino acid.") @@ -45704,8 +119148,86 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:1901605") AnnotationAssertion(rdfs:label "alpha-amino acid metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (alpha-amino acid catabolic process) + +AnnotationAssertion(Annotation( "GOC:TermGenie") "The chemical reactions and pathways resulting in the breakdown of an alpha-amino acid.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2012-11-08T17:39:54Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "alpha-amino acid breakdown") +AnnotationAssertion(Annotation( "GOC:TermGenie") "alpha-amino acid catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "alpha-amino acid degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901606") +AnnotationAssertion(rdfs:label "alpha-amino acid catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (alpha-amino acid biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:TermGenie") "The chemical reactions and pathways resulting in the formation of an alpha-amino acid.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2012-11-08T17:39:58Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "alpha-amino acid anabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "alpha-amino acid biosynthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "alpha-amino acid formation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "alpha-amino acid synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901607") +AnnotationAssertion(rdfs:label "alpha-amino acid biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of vesicle transport along microtubule) + +AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that modulates the frequency, rate or extent of vesicle transport along microtubule.") +AnnotationAssertion( "hjd") +AnnotationAssertion( "2012-11-08T21:49:44Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of microtubule-based vesicle localization") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901608") +AnnotationAssertion(rdfs:label "regulation of vesicle transport along microtubule") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of vesicle transport along microtubule) + +AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that stops, prevents or reduces the frequency, rate or extent of vesicle transport along microtubule.") +AnnotationAssertion( "hjd") +AnnotationAssertion( "2012-11-08T21:49:48Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of microtubule-based vesicle localization") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of vesicle transport along microtubule") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of microtubule-based vesicle localization") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of vesicle transport along microtubule") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of microtubule-based vesicle localization") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of vesicle transport along microtubule") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of microtubule-based vesicle localization") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of microtubule-based vesicle localization") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of vesicle transport along microtubule") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901609") +AnnotationAssertion(rdfs:label "negative regulation of vesicle transport along microtubule") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of vesicle transport along microtubule) + +AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that activates or increases the frequency, rate or extent of vesicle transport along microtubule.") +AnnotationAssertion( "hjd") +AnnotationAssertion( "2012-11-08T21:49:53Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of microtubule-based vesicle localization") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of microtubule-based vesicle localization") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of microtubule-based vesicle localization") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of vesicle transport along microtubule") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of microtubule-based vesicle localization") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of vesicle transport along microtubule") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of microtubule-based vesicle localization") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of vesicle transport along microtubule") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of vesicle transport along microtubule") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901610") +AnnotationAssertion(rdfs:label "positive regulation of vesicle transport along microtubule") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (organic hydroxy compound metabolic process) AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:pr") "The chemical reactions and pathways involving organic hydroxy compound.") @@ -45715,8 +119237,22 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:1901615") AnnotationAssertion(rdfs:label "organic hydroxy compound metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (organic hydroxy compound catabolic process) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:pr") "The chemical reactions and pathways resulting in the breakdown of organic hydroxy compound.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2012-11-13T12:54:31Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "organic hydroxy compound breakdown") +AnnotationAssertion(Annotation( "GOC:TermGenie") "organic hydroxy compound catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "organic hydroxy compound degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901616") +AnnotationAssertion(rdfs:label "organic hydroxy compound catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (organic hydroxy compound biosynthetic process) AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:pr") "The chemical reactions and pathways resulting in the formation of organic hydroxy compound.") @@ -45729,9 +119265,1171 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:1901617") AnnotationAssertion(rdfs:label "organic hydroxy compound biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) +# Class: (organic hydroxy compound transmembrane transporter activity) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:pr") "Enables the transfer of organic hydroxy compound from one side of a membrane to the other.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2012-11-13T12:59:01Z") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:1901618") +AnnotationAssertion(rdfs:label "organic hydroxy compound transmembrane transporter activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of lymphocyte chemotaxis) + +AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that modulates the frequency, rate or extent of lymphocyte chemotaxis.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2012-11-13T23:03:23Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901623") +AnnotationAssertion(rdfs:label "regulation of lymphocyte chemotaxis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of lymphocyte chemotaxis) + +AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that stops, prevents or reduces the frequency, rate or extent of lymphocyte chemotaxis.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2012-11-13T23:03:28Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of lymphocyte chemotaxis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of lymphocyte chemotaxis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of lymphocyte chemotaxis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of lymphocyte chemotaxis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901624") +AnnotationAssertion(rdfs:label "negative regulation of lymphocyte chemotaxis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of postsynaptic membrane organization) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "PMID:22426000") "Any process that modulates the frequency, rate or extent of postsynaptic membrane organization.") +AnnotationAssertion( "ans") +AnnotationAssertion( "2012-11-15T11:40:15Z") +AnnotationAssertion( "regulation of post-synaptic membrane organization") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of postsynaptic membrane organisation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901626") +AnnotationAssertion(rdfs:label "regulation of postsynaptic membrane organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of postsynaptic membrane organization) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "PMID:22426000") "Any process that stops, prevents or reduces the frequency, rate or extent of postsynaptic membrane organization.") +AnnotationAssertion( "ans") +AnnotationAssertion( "2012-11-15T11:40:20Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of postsynaptic membrane organisation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of postsynaptic membrane organization") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of postsynaptic membrane organisation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of postsynaptic membrane organization") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of postsynaptic membrane organisation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of postsynaptic membrane organization") +AnnotationAssertion( "negative regulation of post-synaptic membrane organization") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of postsynaptic membrane organisation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of postsynaptic membrane organisation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of postsynaptic membrane organization") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901627") +AnnotationAssertion(rdfs:label "negative regulation of postsynaptic membrane organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (positive regulation of postsynaptic membrane organization) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "PMID:22426000") "Any process that activates or increases the frequency, rate or extent of postsynaptic membrane organization.") +AnnotationAssertion( "ans") +AnnotationAssertion( "2012-11-15T11:40:24Z") +AnnotationAssertion( "positive regulation of post-synaptic membrane organization") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of postsynaptic membrane organisation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of postsynaptic membrane organisation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of postsynaptic membrane organization") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of postsynaptic membrane organisation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of postsynaptic membrane organization") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of postsynaptic membrane organisation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of postsynaptic membrane organization") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of postsynaptic membrane organisation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of postsynaptic membrane organization") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901628") +AnnotationAssertion(rdfs:label "positive regulation of postsynaptic membrane organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (nucleoside transmembrane transport) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:pr") "The directed movement of nucleoside across a membrane.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2012-11-16T13:32:01Z") +AnnotationAssertion( "nucleoside membrane transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901642") +AnnotationAssertion(rdfs:comment "Note that this term is not intended for use in annotating lateral movement within membranes.") +AnnotationAssertion(rdfs:label "nucleoside transmembrane transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (regulation of synoviocyte proliferation) + +AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that modulates the frequency, rate or extent of synoviocyte proliferation.") +AnnotationAssertion( "hjd") +AnnotationAssertion( "2012-11-16T20:16:23Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901645") +AnnotationAssertion(rdfs:label "regulation of synoviocyte proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of synoviocyte proliferation) + +AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that stops, prevents or reduces the frequency, rate or extent of synoviocyte proliferation.") +AnnotationAssertion( "hjd") +AnnotationAssertion( "2012-11-16T20:16:27Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of synoviocyte proliferation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of synoviocyte proliferation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of synoviocyte proliferation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of synoviocyte proliferation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901646") +AnnotationAssertion(rdfs:label "negative regulation of synoviocyte proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of synoviocyte proliferation) + +AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that activates or increases the frequency, rate or extent of synoviocyte proliferation.") +AnnotationAssertion( "hjd") +AnnotationAssertion( "2012-11-16T20:16:32Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of synoviocyte proliferation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of synoviocyte proliferation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of synoviocyte proliferation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of synoviocyte proliferation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901647") +AnnotationAssertion(rdfs:label "positive regulation of synoviocyte proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (response to peptide) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:pr") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide stimulus.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2012-11-20T09:45:15Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901652") +AnnotationAssertion(rdfs:label "response to peptide") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (cellular response to peptide) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:pr") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide stimulus.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2012-11-20T09:45:19Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901653") +AnnotationAssertion(rdfs:label "cellular response to peptide") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (response to ketone) + +AnnotationAssertion(Annotation( "GOC:mengo_curators") Annotation( "PMID:23356676") "A response that results in a state of tolerance to ketone.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2012-11-20T10:55:47Z") +AnnotationAssertion( "GO:1990369") +AnnotationAssertion( "process resulting in tolerance to ketone") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901654") +AnnotationAssertion(rdfs:label "response to ketone") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (cellular response to ketone) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:pr") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ketone stimulus.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2012-11-20T10:55:51Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901655") +AnnotationAssertion(rdfs:label "cellular response to ketone") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (glycosyl compound metabolic process) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:pr") "The chemical reactions and pathways involving glycosyl compound.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2012-11-20T14:24:07Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "glycosyl compound metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901657") +AnnotationAssertion(rdfs:label "glycosyl compound metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (glycosyl compound catabolic process) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:pr") "The chemical reactions and pathways resulting in the breakdown of glycosyl compound.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2012-11-20T14:24:11Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "glycosyl compound breakdown") +AnnotationAssertion(Annotation( "GOC:TermGenie") "glycosyl compound catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "glycosyl compound degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901658") +AnnotationAssertion(rdfs:label "glycosyl compound catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (glycosyl compound biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:pr") "The chemical reactions and pathways resulting in the formation of glycosyl compound.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2012-11-20T14:24:19Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "glycosyl compound anabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "glycosyl compound biosynthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "glycosyl compound formation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "glycosyl compound synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901659") +AnnotationAssertion(rdfs:label "glycosyl compound biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (nucleotide transmembrane transport) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:pr") "The directed movement of nucleotide across a membrane.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2012-11-22T15:43:23Z") +AnnotationAssertion( "nucleotide membrane transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901679") +AnnotationAssertion(rdfs:comment "Note that this term is not intended for use in annotating lateral movement within membranes.") +AnnotationAssertion(rdfs:label "nucleotide transmembrane transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (sulfur compound binding) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:pr") "Binding to a sulfur compound.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2012-11-26T20:45:23Z") +AnnotationAssertion( "sulfur molecular entity binding") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:1901681") +AnnotationAssertion(rdfs:label "sulfur compound binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (sulfur compound transmembrane transporter activity) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:pr") "Enables the transfer of a sulfur compound from one side of a membrane to the other.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2012-11-26T20:45:29Z") +AnnotationAssertion( "sulfur molecular entity transmembrane transporter activity") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:1901682") +AnnotationAssertion(rdfs:label "sulfur compound transmembrane transporter activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of compound eye retinal cell apoptotic process) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mtg_apoptosis") Annotation( "PMID:12021768") "Any process that modulates the frequency, rate or extent of compound eye retinal cell apoptotic process.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2012-12-12T10:28:35Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901692") +AnnotationAssertion(rdfs:label "regulation of compound eye retinal cell apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of compound eye retinal cell apoptotic process) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mtg_apoptosis") Annotation( "PMID:12021768") "Any process that stops, prevents or reduces the frequency, rate or extent of compound eye retinal cell apoptotic process.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2012-12-12T10:28:40Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of compound eye retinal cell apoptotic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of compound eye retinal cell apoptotic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of compound eye retinal cell apoptotic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of compound eye retinal cell apoptotic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901693") +AnnotationAssertion(rdfs:label "negative regulation of compound eye retinal cell apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of compound eye retinal cell apoptotic process) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mtg_apoptosis") Annotation( "PMID:12021768") "Any process that activates or increases the frequency, rate or extent of compound eye retinal cell apoptotic process.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2012-12-12T10:28:45Z") +AnnotationAssertion( "GO:0046675") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of compound eye retinal cell apoptotic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of compound eye retinal cell apoptotic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of compound eye retinal cell apoptotic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of compound eye retinal cell apoptotic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "induction of compound eye retinal cell programmed cell death") +AnnotationAssertion( "GO:1901694") +AnnotationAssertion(rdfs:label "positive regulation of compound eye retinal cell apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (response to nitrogen compound) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:pr") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen compound stimulus.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2012-12-13T15:06:08Z") +AnnotationAssertion( "response to nitrogen molecular entity") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901698") +AnnotationAssertion(rdfs:label "response to nitrogen compound") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (cellular response to nitrogen compound) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:pr") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen compound stimulus.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2012-12-13T15:06:13Z") +AnnotationAssertion( "cellular response to nitrogen molecular entity") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901699") +AnnotationAssertion(rdfs:label "cellular response to nitrogen compound") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (response to oxygen-containing compound) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:pr") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen-containing compound stimulus.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2012-12-13T15:11:37Z") +AnnotationAssertion( "response to oxygen molecular entity") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901700") +AnnotationAssertion(rdfs:label "response to oxygen-containing compound") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (cellular response to oxygen-containing compound) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:pr") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen-containing compound stimulus.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2012-12-13T15:11:42Z") +AnnotationAssertion( "cellular response to oxygen molecular entity") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901701") +AnnotationAssertion(rdfs:label "cellular response to oxygen-containing compound") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (salt transmembrane transporter activity) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:pr") "Enables the transfer of salt from one side of a membrane to the other.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2012-12-13T15:14:47Z") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:1901702") +AnnotationAssertion(rdfs:label "salt transmembrane transporter activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (mesenchymal cell differentiation involved in bone development) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:hjd") Annotation( "PMID:21571217") "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of bone as it progresses from its formation to the mature state.") +AnnotationAssertion( "hjd") +AnnotationAssertion( "2012-12-14T16:04:16Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901706") +AnnotationAssertion(rdfs:label "mesenchymal cell differentiation involved in bone development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of gamma-aminobutyric acid catabolic process) + +AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that modulates the frequency, rate or extent of gamma-aminobutyric acid catabolic process.") +AnnotationAssertion( "mcc") +AnnotationAssertion( "2012-12-19T16:13:24Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of 4-aminobutanoate catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of 4-aminobutanoate catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of 4-aminobutyrate catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of 4-aminobutyrate catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of GABA catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of GABA catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of gamma-aminobutyric acid breakdown") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of gamma-aminobutyric acid catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of gamma-aminobutyric acid degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901715") +AnnotationAssertion(rdfs:label "regulation of gamma-aminobutyric acid catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of gamma-aminobutyric acid catabolic process) + +AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that stops, prevents or reduces the frequency, rate or extent of gamma-aminobutyric acid catabolic process.") +AnnotationAssertion( "mcc") +AnnotationAssertion( "2012-12-19T16:13:31Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of 4-aminobutanoate catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of 4-aminobutanoate catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of 4-aminobutyrate catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of 4-aminobutyrate catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of GABA catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of GABA catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of gamma-aminobutyric acid breakdown") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of gamma-aminobutyric acid catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of gamma-aminobutyric acid catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of gamma-aminobutyric acid degradation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of 4-aminobutanoate catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of 4-aminobutanoate catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of 4-aminobutyrate catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of 4-aminobutyrate catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of GABA catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of GABA catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of gamma-aminobutyric acid breakdown") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of gamma-aminobutyric acid catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of gamma-aminobutyric acid catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of gamma-aminobutyric acid degradation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of 4-aminobutanoate catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of 4-aminobutanoate catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of 4-aminobutyrate catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of 4-aminobutyrate catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of GABA catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of GABA catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of gamma-aminobutyric acid breakdown") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of gamma-aminobutyric acid catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of gamma-aminobutyric acid catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of gamma-aminobutyric acid degradation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of 4-aminobutanoate catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of 4-aminobutanoate catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of 4-aminobutyrate catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of 4-aminobutyrate catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of GABA catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of GABA catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of gamma-aminobutyric acid breakdown") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of gamma-aminobutyric acid catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of gamma-aminobutyric acid degradation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of 4-aminobutanoate catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of 4-aminobutanoate catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of 4-aminobutyrate catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of 4-aminobutyrate catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of GABA catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of GABA catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of gamma-aminobutyric acid breakdown") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of gamma-aminobutyric acid catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of gamma-aminobutyric acid degradation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of gamma-aminobutyric acid catabolic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901716") +AnnotationAssertion(rdfs:label "negative regulation of gamma-aminobutyric acid catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of gamma-aminobutyric acid catabolic process) + +AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that activates or increases the frequency, rate or extent of gamma-aminobutyric acid catabolic process.") +AnnotationAssertion( "mcc") +AnnotationAssertion( "2012-12-19T16:13:36Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of 4-aminobutanoate catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of 4-aminobutanoate catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of 4-aminobutyrate catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of 4-aminobutyrate catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of GABA catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of GABA catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of gamma-aminobutyric acid breakdown") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of gamma-aminobutyric acid catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of gamma-aminobutyric acid degradation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of 4-aminobutanoate catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of 4-aminobutanoate catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of 4-aminobutyrate catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of 4-aminobutyrate catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of GABA catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of GABA catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of gamma-aminobutyric acid breakdown") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of gamma-aminobutyric acid catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of gamma-aminobutyric acid degradation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of 4-aminobutanoate catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of 4-aminobutanoate catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of 4-aminobutyrate catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of 4-aminobutyrate catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of GABA catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of GABA catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of gamma-aminobutyric acid breakdown") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of gamma-aminobutyric acid catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of gamma-aminobutyric acid catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of gamma-aminobutyric acid degradation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of 4-aminobutanoate catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of 4-aminobutanoate catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of 4-aminobutyrate catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of 4-aminobutyrate catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of GABA catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of GABA catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of gamma-aminobutyric acid breakdown") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of gamma-aminobutyric acid catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of gamma-aminobutyric acid catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of gamma-aminobutyric acid degradation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of 4-aminobutanoate catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of 4-aminobutanoate catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of 4-aminobutyrate catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of 4-aminobutyrate catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of GABA catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of GABA catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of gamma-aminobutyric acid breakdown") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of gamma-aminobutyric acid catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of gamma-aminobutyric acid catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of gamma-aminobutyric acid degradation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of gamma-aminobutyric acid catabolic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901717") +AnnotationAssertion(rdfs:label "positive regulation of gamma-aminobutyric acid catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of cell proliferation involved in kidney development) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "PMID:18182616") "Any process that modulates the frequency, rate or extent of cell proliferation involved in kidney development.") +AnnotationAssertion( "krc") +AnnotationAssertion( "2012-12-27T19:30:31Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901722") +AnnotationAssertion(rdfs:label "regulation of cell proliferation involved in kidney development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of cell proliferation involved in kidney development) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "PMID:18182616") "Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation involved in kidney development.") +AnnotationAssertion( "krc") +AnnotationAssertion( "2012-12-27T19:30:35Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of cell proliferation involved in kidney development") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of cell proliferation involved in kidney development") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of cell proliferation involved in kidney development") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of cell proliferation involved in kidney development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901723") +AnnotationAssertion(rdfs:label "negative regulation of cell proliferation involved in kidney development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of cell proliferation involved in kidney development) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "PMID:18182616") "Any process that activates or increases the frequency, rate or extent of cell proliferation involved in kidney development.") +AnnotationAssertion( "krc") +AnnotationAssertion( "2012-12-27T19:30:40Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of cell proliferation involved in kidney development") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of cell proliferation involved in kidney development") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of cell proliferation involved in kidney development") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of cell proliferation involved in kidney development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901724") +AnnotationAssertion(rdfs:label "positive regulation of cell proliferation involved in kidney development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (beta-carotene metabolic process) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:yaf") Annotation( "MetaCyc:PWY-5943") Annotation( "PMID:11387982") Annotation( "UniPathway:UPA00802") "The chemical reactions and pathways involving beta-carotene.") +AnnotationAssertion( "yaf") +AnnotationAssertion( "2013-01-22T10:30:23Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "beta-carotene metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901810") +AnnotationAssertion(rdfs:label "beta-carotene metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (beta-carotene catabolic process) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:yaf") Annotation( "MetaCyc:PWY-5943") Annotation( "PMID:11387982") Annotation( "UniPathway:UPA00802") "The chemical reactions and pathways resulting in the breakdown of beta-carotene.") +AnnotationAssertion( "yaf") +AnnotationAssertion( "2013-01-22T10:30:28Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "beta-carotene breakdown") +AnnotationAssertion(Annotation( "GOC:TermGenie") "beta-carotene catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "beta-carotene degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901811") +AnnotationAssertion(rdfs:label "beta-carotene catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (beta-carotene biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:yaf") Annotation( "MetaCyc:PWY-5943") Annotation( "PMID:11387982") Annotation( "UniPathway:UPA00802") "The chemical reactions and pathways resulting in the formation of beta-carotene.") +AnnotationAssertion( "yaf") +AnnotationAssertion( "2013-01-22T10:30:32Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "beta-carotene anabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "beta-carotene biosynthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "beta-carotene formation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "beta-carotene synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901812") +AnnotationAssertion(rdfs:label "beta-carotene biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (zeaxanthin metabolic process) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:yaf") Annotation( "MetaCyc:PWY-5944") Annotation( "UniPathway:UPA00843") "The chemical reactions and pathways involving zeaxanthin.") +AnnotationAssertion( "yaf") +AnnotationAssertion( "2013-01-22T11:36:55Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "zeaxanthin metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901825") +AnnotationAssertion(rdfs:label "zeaxanthin metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (zeaxanthin catabolic process) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:yaf") Annotation( "MetaCyc:PWY-5944") Annotation( "UniPathway:UPA00843") "The chemical reactions and pathways resulting in the breakdown of zeaxanthin.") +AnnotationAssertion( "yaf") +AnnotationAssertion( "2013-01-22T11:37:00Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "zeaxanthin breakdown") +AnnotationAssertion(Annotation( "GOC:TermGenie") "zeaxanthin catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "zeaxanthin degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901826") +AnnotationAssertion(rdfs:label "zeaxanthin catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (zeaxanthin biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:yaf") Annotation( "MetaCyc:PWY-5944") Annotation( "UniPathway:UPA00843") "The chemical reactions and pathways resulting in the formation of zeaxanthin.") +AnnotationAssertion( "yaf") +AnnotationAssertion( "2013-01-22T11:37:07Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "zeaxanthin anabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "zeaxanthin biosynthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "zeaxanthin formation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "zeaxanthin synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901827") +AnnotationAssertion(rdfs:label "zeaxanthin biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of muscle tissue development) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:yaf") Annotation( "PMID:23150719") "Any process that modulates the frequency, rate or extent of muscle tissue development.") +AnnotationAssertion( "yaf") +AnnotationAssertion( "2013-02-01T10:30:47Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901861") +AnnotationAssertion(rdfs:label "regulation of muscle tissue development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of muscle tissue development) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:yaf") Annotation( "PMID:23150719") "Any process that stops, prevents or reduces the frequency, rate or extent of muscle tissue development.") +AnnotationAssertion( "yaf") +AnnotationAssertion( "2013-02-01T10:30:52Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of muscle tissue development") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of muscle tissue development") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of muscle tissue development") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of muscle tissue development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901862") +AnnotationAssertion(rdfs:label "negative regulation of muscle tissue development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of muscle tissue development) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:yaf") Annotation( "PMID:23150719") "Any process that activates or increases the frequency, rate or extent of muscle tissue development.") +AnnotationAssertion( "yaf") +AnnotationAssertion( "2013-02-01T10:30:57Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of muscle tissue development") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of muscle tissue development") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of muscle tissue development") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of muscle tissue development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901863") +AnnotationAssertion(rdfs:label "positive regulation of muscle tissue development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of calcium ion binding) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "PMID:16432188") "Any process that modulates the frequency, rate or extent of calcium ion binding.") +AnnotationAssertion( "rl") +AnnotationAssertion( "2013-02-06T12:38:12Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of calcium ion storage activity") +AnnotationAssertion( "GO:1901876") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "regulation of calcium ion binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of calcium ion binding) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "PMID:16432188") "Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion binding.") +AnnotationAssertion( "rl") +AnnotationAssertion( "2013-02-06T12:38:22Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of calcium ion binding") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of calcium ion binding") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of calcium ion binding") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of calcium ion binding") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of calcium ion storage activity") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of calcium ion storage activity") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of calcium ion storage activity") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of calcium ion storage activity") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of calcium ion storage activity") +AnnotationAssertion( "GO:1901877") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "negative regulation of calcium ion binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of calcium ion binding) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "PMID:16432188") "Any process that activates or increases the frequency, rate or extent of calcium ion binding.") +AnnotationAssertion( "rl") +AnnotationAssertion( "2013-02-06T12:38:26Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of calcium ion binding") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of calcium ion binding") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of calcium ion binding") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of calcium ion binding") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of calcium ion storage activity") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of calcium ion storage activity") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of calcium ion storage activity") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of calcium ion storage activity") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of calcium ion storage activity") +AnnotationAssertion( "GO:1901878") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "positive regulation of calcium ion binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of protein depolymerization) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "PMID:12032137") "Any process that modulates the frequency, rate or extent of protein depolymerization.") +AnnotationAssertion( "rl") +AnnotationAssertion( "2013-02-06T13:57:23Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of protein polymer breakdown") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of protein polymer catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of protein polymer catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of protein polymer degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901879") +AnnotationAssertion(rdfs:label "regulation of protein depolymerization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of protein depolymerization) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "PMID:12032137") "Any process that stops, prevents or reduces the frequency, rate or extent of protein depolymerization.") +AnnotationAssertion( "rl") +AnnotationAssertion( "2013-02-06T13:57:28Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of protein depolymerization") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of protein polymer breakdown") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of protein polymer catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of protein polymer catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of protein polymer degradation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of protein depolymerization") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of protein polymer breakdown") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of protein polymer catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of protein polymer catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of protein polymer degradation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of protein depolymerization") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of protein polymer breakdown") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of protein polymer catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of protein polymer catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of protein polymer degradation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of protein polymer breakdown") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of protein polymer catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of protein polymer catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of protein polymer degradation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of protein polymer breakdown") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of protein polymer catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of protein polymer catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of protein polymer degradation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of protein depolymerization") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901880") +AnnotationAssertion(rdfs:label "negative regulation of protein depolymerization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of protein depolymerization) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "PMID:12032137") "Any process that activates or increases the frequency, rate or extent of protein depolymerization.") +AnnotationAssertion( "rl") +AnnotationAssertion( "2013-02-06T13:57:32Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of protein polymer breakdown") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of protein polymer catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of protein polymer catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of protein polymer degradation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of protein polymer breakdown") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of protein polymer catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of protein polymer catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of protein polymer degradation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of protein depolymerization") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of protein polymer breakdown") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of protein polymer catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of protein polymer catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of protein polymer degradation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of protein depolymerization") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of protein polymer breakdown") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of protein polymer catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of protein polymer catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of protein polymer degradation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of protein depolymerization") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of protein polymer breakdown") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of protein polymer catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of protein polymer catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of protein polymer degradation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of protein depolymerization") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901881") +AnnotationAssertion(rdfs:label "positive regulation of protein depolymerization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of cell junction assembly) + +AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that modulates the frequency, rate or extent of cell junction assembly.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2013-02-06T19:40:32Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901888") +AnnotationAssertion(rdfs:label "regulation of cell junction assembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (negative regulation of cell junction assembly) + +AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that stops, prevents or reduces the frequency, rate or extent of cell junction assembly.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2013-02-06T19:40:41Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of cell junction assembly") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of cell junction assembly") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of cell junction assembly") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of cell junction assembly") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901889") +AnnotationAssertion(rdfs:label "negative regulation of cell junction assembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of cell junction assembly) + +AnnotationAssertion(Annotation( "GOC:TermGenie") "Any process that activates or increases the frequency, rate or extent of cell junction assembly.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2013-02-06T19:40:46Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of cell junction assembly") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of cell junction assembly") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of cell junction assembly") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of cell junction assembly") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901890") +AnnotationAssertion(rdfs:label "positive regulation of cell junction assembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (dense core granule transport) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:kmv") Annotation( "PMID:23358451") "The directed movement a dense core granule within a cell.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2013-02-19T13:00:52Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "dense core vesicle transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901950") +AnnotationAssertion(rdfs:comment "goslim_synapse") +AnnotationAssertion(rdfs:label "dense core granule transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of anterograde dense core granule transport) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:kmv") Annotation( "PMID:23358451") "Any process that modulates the frequency, rate or extent of anterograde dense core granule transport.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2013-02-19T13:36:21Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901951") +AnnotationAssertion(rdfs:label "regulation of anterograde dense core granule transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of anterograde dense core granule transport) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:kmv") Annotation( "PMID:23358451") "Any process that stops, prevents or reduces the frequency, rate or extent of anterograde dense core granule transport.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2013-02-19T13:36:30Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of anterograde dense core granule transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of anterograde dense core granule transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of anterograde dense core granule transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of anterograde dense core granule transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901952") +AnnotationAssertion(rdfs:label "negative regulation of anterograde dense core granule transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of anterograde dense core granule transport) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:kmv") Annotation( "PMID:23358451") "Any process that activates or increases the frequency, rate or extent of anterograde dense core granule transport.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2013-02-19T13:36:35Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of anterograde dense core granule transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of anterograde dense core granule transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of anterograde dense core granule transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of anterograde dense core granule transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901953") +AnnotationAssertion(rdfs:label "positive regulation of anterograde dense core granule transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of retrograde dense core granule transport) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:kmv") Annotation( "PMID:23358451") "Any process that modulates the frequency, rate or extent of retrograde dense core granule transport.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2013-02-19T13:36:43Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901954") +AnnotationAssertion(rdfs:label "regulation of retrograde dense core granule transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of retrograde dense core granule transport) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:kmv") Annotation( "PMID:23358451") "Any process that stops, prevents or reduces the frequency, rate or extent of retrograde dense core granule transport.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2013-02-19T13:36:47Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of retrograde dense core granule transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of retrograde dense core granule transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of retrograde dense core granule transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of retrograde dense core granule transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901955") +AnnotationAssertion(rdfs:label "negative regulation of retrograde dense core granule transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of retrograde dense core granule transport) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:kmv") Annotation( "PMID:23358451") "Any process that activates or increases the frequency, rate or extent of retrograde dense core granule transport.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2013-02-19T13:36:52Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of retrograde dense core granule transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of retrograde dense core granule transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of retrograde dense core granule transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of retrograde dense core granule transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901956") +AnnotationAssertion(rdfs:label "positive regulation of retrograde dense core granule transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of cell proliferation involved in outflow tract morphogenesis) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:dph") Annotation( "GOC:mtg_heart") Annotation( "PMID:21419760") "Any process that modulates the frequency, rate or extent of cell proliferation involved in outflow tract morphogenesis.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2013-02-20T20:30:26Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901963") +AnnotationAssertion(rdfs:label "regulation of cell proliferation involved in outflow tract morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of cell proliferation involved in outflow tract morphogenesis) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:dph") Annotation( "GOC:mtg_heart") Annotation( "PMID:21419760") "Any process that activates or increases the frequency, rate or extent of cell proliferation involved in outflow tract morphogenesis.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2013-02-20T20:30:31Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of cell proliferation involved in outflow tract morphogenesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of cell proliferation involved in outflow tract morphogenesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of cell proliferation involved in outflow tract morphogenesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of cell proliferation involved in outflow tract morphogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1901964") +AnnotationAssertion(rdfs:label "positive regulation of cell proliferation involved in outflow tract morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (fatty acid transmembrane transport) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:rb") Annotation( "PMID:9395310") "The process in which a fatty acid is transported across a membrane.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2013-03-21T09:57:00Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902001") +AnnotationAssertion(rdfs:label "fatty acid transmembrane transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (regulation of cilium assembly) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:cilia") Annotation( "GOC:dph") Annotation( "PMID:17719545") "Any process that modulates the frequency, rate or extent of cilium assembly.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2013-03-26T18:10:51Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of ciliogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of cilium biogenesis") +AnnotationAssertion( "GO:1902017") +AnnotationAssertion(rdfs:label "regulation of cilium assembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of cilium assembly) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:cilia") Annotation( "GOC:dph") Annotation( "PMID:17719545") "Any process that stops, prevents or reduces the frequency, rate or extent of cilium assembly.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2013-03-26T18:10:56Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of ciliogenesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of cilium assembly") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of ciliogenesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of cilium assembly") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of ciliogenesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of cilium assembly") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of ciliogenesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of ciliogenesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of cilium assembly") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of cilium biogenesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of cilium biogenesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of cilium biogenesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of cilium biogenesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of cilium biogenesis") +AnnotationAssertion( "GO:1902018") +AnnotationAssertion(rdfs:label "negative regulation of cilium assembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of cilium-dependent cell motility) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:cilia") Annotation( "GOC:jl") "Any process that modulates the frequency, rate or extent of cilium-dependent cell motility.") +AnnotationAssertion( "jl") +AnnotationAssertion( "2013-03-27T14:42:38Z") +AnnotationAssertion( "regulation of cilium cell motility") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "regulation of ciliary cell motility") +AnnotationAssertion( "GO:1902019") +AnnotationAssertion(rdfs:label "regulation of cilium-dependent cell motility") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of cilium-dependent cell motility) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:cilia") Annotation( "GOC:jl") "Any process that stops, prevents or reduces the frequency, rate or extent of cilium-dependent cell motility.") +AnnotationAssertion( "jl") +AnnotationAssertion( "2013-03-27T14:42:42Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of ciliary cell motility") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of ciliary cell motility") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of ciliary cell motility") +AnnotationAssertion( "negative regulation of cilium cell motility") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of ciliary cell motility") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "negative regulation of ciliary cell motility") +AnnotationAssertion( "GO:1902020") +AnnotationAssertion(rdfs:label "negative regulation of cilium-dependent cell motility") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of hematopoietic stem cell proliferation) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "PMID:23403623") "Any process that modulates the frequency, rate or extent of hematopoietic stem cell proliferation.") +AnnotationAssertion( "ss") +AnnotationAssertion( "2013-04-02T05:13:19Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of hemopoietic stem cell proliferation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902033") +AnnotationAssertion(rdfs:label "regulation of hematopoietic stem cell proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of hematopoietic stem cell proliferation) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "PMID:23403623") "Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic stem cell proliferation.") +AnnotationAssertion( "ss") +AnnotationAssertion( "2013-04-02T05:13:24Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of hematopoietic stem cell proliferation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of hemopoietic stem cell proliferation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of hematopoietic stem cell proliferation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of hemopoietic stem cell proliferation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of hematopoietic stem cell proliferation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of hemopoietic stem cell proliferation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of hemopoietic stem cell proliferation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of hematopoietic stem cell proliferation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of hemopoietic stem cell proliferation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902034") +AnnotationAssertion(rdfs:label "negative regulation of hematopoietic stem cell proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (positive regulation of hematopoietic stem cell proliferation) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "PMID:23403623") "Any process that activates or increases the frequency, rate or extent of hematopoietic stem cell proliferation.") +AnnotationAssertion( "ss") +AnnotationAssertion( "2013-04-02T05:13:31Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of hemopoietic stem cell proliferation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of hematopoietic stem cell proliferation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of hemopoietic stem cell proliferation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of hematopoietic stem cell proliferation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of hemopoietic stem cell proliferation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of hematopoietic stem cell proliferation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of hemopoietic stem cell proliferation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of hematopoietic stem cell proliferation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of hemopoietic stem cell proliferation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902035") +AnnotationAssertion(rdfs:label "positive regulation of hematopoietic stem cell proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of hematopoietic stem cell differentiation) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "PMID:23403623") "Any process that modulates the frequency, rate or extent of hematopoietic stem cell differentiation.") +AnnotationAssertion( "ss") +AnnotationAssertion( "2013-04-02T05:19:09Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of haematopoietic stem cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of haemopoietic stem cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of hemopoietic stem cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902036") +AnnotationAssertion(rdfs:label "regulation of hematopoietic stem cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of hematopoietic stem cell differentiation) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "PMID:23403623") "Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic stem cell differentiation.") +AnnotationAssertion( "ss") +AnnotationAssertion( "2013-04-02T05:19:14Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of haematopoietic stem cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of haemopoietic stem cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of hematopoietic stem cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of hemopoietic stem cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of haematopoietic stem cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of haemopoietic stem cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of hematopoietic stem cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of hemopoietic stem cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of haematopoietic stem cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of haemopoietic stem cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of hematopoietic stem cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of hemopoietic stem cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of haematopoietic stem cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of haemopoietic stem cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of hemopoietic stem cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of haematopoietic stem cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of haemopoietic stem cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of hematopoietic stem cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of hemopoietic stem cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902037") +AnnotationAssertion(rdfs:label "negative regulation of hematopoietic stem cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of hematopoietic stem cell differentiation) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "PMID:23403623") "Any process that activates or increases the frequency, rate or extent of hematopoietic stem cell differentiation.") +AnnotationAssertion( "ss") +AnnotationAssertion( "2013-04-02T05:19:19Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of haematopoietic stem cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of haemopoietic stem cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of hemopoietic stem cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of haematopoietic stem cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of haemopoietic stem cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of hematopoietic stem cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of hemopoietic stem cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of haematopoietic stem cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of haemopoietic stem cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of hematopoietic stem cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of hemopoietic stem cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of haematopoietic stem cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of haemopoietic stem cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of hematopoietic stem cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of hemopoietic stem cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of haematopoietic stem cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of haemopoietic stem cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of hematopoietic stem cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of hemopoietic stem cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902038") +AnnotationAssertion(rdfs:label "positive regulation of hematopoietic stem cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (response to L-glutamate) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "PMID:23574009") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an L-glutamate stimulus.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2013-04-16T21:21:14Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902065") +AnnotationAssertion(rdfs:label "response to L-glutamate") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (response to salt) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mls") Annotation( "PMID:16666921") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a salt stimulus.") +AnnotationAssertion( "mls") +AnnotationAssertion( "2013-04-22T15:41:57Z") +AnnotationAssertion(Annotation( "GOC:mls") "response to salinity") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902074") +AnnotationAssertion(rdfs:label "response to salt") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (cellular response to salt) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mls") Annotation( "PMID:16666921") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a salt stimulus.") +AnnotationAssertion( "mls") +AnnotationAssertion( "2013-04-22T15:42:02Z") +AnnotationAssertion(Annotation( "GOC:mls") "cellular response to salinity") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902075") +AnnotationAssertion(rdfs:label "cellular response to salt") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (positive regulation of flagellated sperm motility) AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:cilia") Annotation( "GOC:jh2") Annotation( "GOC:krc") Annotation( "PMID:7513657") "Any process that activates or increases the frequency, rate or extent of flagellated sperm motility.") @@ -45750,9 +120448,3915 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:1902093") AnnotationAssertion(rdfs:label "positive regulation of flagellated sperm motility") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) +# Class: (regulation of leukocyte differentiation) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:add") "Any process that modulates the frequency, rate or extent of leukocyte differentiation.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2013-05-02T17:32:42Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of immune cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of leucocyte differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902105") +AnnotationAssertion(rdfs:label "regulation of leukocyte differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of leukocyte differentiation) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:add") "Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte differentiation.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2013-05-02T17:32:47Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of immune cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of leucocyte differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of leukocyte differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of immune cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of leucocyte differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of leukocyte differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of immune cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of leucocyte differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of leukocyte differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of immune cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of leucocyte differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of immune cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of leucocyte differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of leukocyte differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902106") +AnnotationAssertion(rdfs:label "negative regulation of leukocyte differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of leukocyte differentiation) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:add") "Any process that activates or increases the frequency, rate or extent of leukocyte differentiation.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2013-05-02T17:32:52Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of immune cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of leucocyte differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of immune cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of leucocyte differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of leukocyte differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of immune cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of leucocyte differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of leukocyte differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of immune cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of leucocyte differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of leukocyte differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of immune cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of leucocyte differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of leukocyte differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902107") +AnnotationAssertion(rdfs:label "positive regulation of leukocyte differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of organelle assembly) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:pr") "Any process that modulates the frequency, rate or extent of organelle assembly.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2013-05-14T09:43:21Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902115") +AnnotationAssertion(rdfs:label "regulation of organelle assembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (negative regulation of organelle assembly) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:pr") "Any process that stops, prevents or reduces the frequency, rate or extent of organelle assembly.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2013-05-14T09:43:31Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of organelle assembly") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of organelle assembly") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of organelle assembly") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of organelle assembly") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902116") +AnnotationAssertion(rdfs:label "negative regulation of organelle assembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of organelle assembly) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:pr") "Any process that activates or increases the frequency, rate or extent of organelle assembly.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2013-05-14T09:43:36Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of organelle assembly") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of organelle assembly") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of organelle assembly") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of organelle assembly") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902117") +AnnotationAssertion(rdfs:label "positive regulation of organelle assembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (regulation of keratinocyte apoptotic process) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:rl") Annotation( "PMID:18938133") "Any process that modulates the frequency, rate or extent of keratinocyte apoptotic process.") +AnnotationAssertion( "rl") +AnnotationAssertion( "2013-05-29T14:36:11Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of keratinocyte apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902172") +AnnotationAssertion(rdfs:label "regulation of keratinocyte apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of keratinocyte apoptotic process) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:rl") Annotation( "PMID:18938133") "Any process that stops, prevents or reduces the frequency, rate or extent of keratinocyte apoptotic process.") +AnnotationAssertion( "rl") +AnnotationAssertion( "2013-05-29T14:36:15Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of keratinocyte apoptotic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of keratinocyte apoptotic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of keratinocyte apoptotic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of keratinocyte apoptosis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of keratinocyte apoptosis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of keratinocyte apoptosis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of keratinocyte apoptosis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of keratinocyte apoptotic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of keratinocyte apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902173") +AnnotationAssertion(rdfs:label "negative regulation of keratinocyte apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of keratinocyte apoptotic process) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:rl") Annotation( "PMID:18938133") "Any process that activates or increases the frequency, rate or extent of keratinocyte apoptotic process.") +AnnotationAssertion( "rl") +AnnotationAssertion( "2013-05-29T14:36:21Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of keratinocyte apoptotic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of keratinocyte apoptotic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of keratinocyte apoptotic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of keratinocyte apoptosis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of keratinocyte apoptotic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of keratinocyte apoptosis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of keratinocyte apoptosis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of keratinocyte apoptosis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of keratinocyte apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902174") +AnnotationAssertion(rdfs:label "positive regulation of keratinocyte apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of prolactin signaling pathway) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "PMID:11773439") "Any process that modulates the frequency, rate or extent of prolactin signaling pathway.") +AnnotationAssertion( "lb") +AnnotationAssertion( "2013-06-12T10:10:07Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of PRL signaling pathway") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of prolactin-mediated signaling pathway") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902211") +AnnotationAssertion(rdfs:label "regulation of prolactin signaling pathway") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of prolactin signaling pathway) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "PMID:11773439") "Any process that stops, prevents or reduces the frequency, rate or extent of prolactin signaling pathway.") +AnnotationAssertion( "lb") +AnnotationAssertion( "2013-06-12T10:10:12Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of PRL signaling pathway") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of prolactin signaling pathway") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of prolactin-mediated signaling pathway") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of PRL signaling pathway") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of prolactin signaling pathway") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of prolactin-mediated signaling pathway") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of PRL signaling pathway") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of prolactin signaling pathway") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of prolactin-mediated signaling pathway") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of PRL signaling pathway") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of prolactin-mediated signaling pathway") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of PRL signaling pathway") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of prolactin signaling pathway") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of prolactin-mediated signaling pathway") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902212") +AnnotationAssertion(rdfs:label "negative regulation of prolactin signaling pathway") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of prolactin signaling pathway) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "PMID:11773439") "Any process that activates or increases the frequency, rate or extent of prolactin signaling pathway.") +AnnotationAssertion( "lb") +AnnotationAssertion( "2013-06-12T10:10:18Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of PRL signaling pathway") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of prolactin-mediated signaling pathway") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of PRL signaling pathway") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of prolactin signaling pathway") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of prolactin-mediated signaling pathway") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of PRL signaling pathway") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of prolactin signaling pathway") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of prolactin-mediated signaling pathway") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of PRL signaling pathway") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of prolactin signaling pathway") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of prolactin-mediated signaling pathway") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of PRL signaling pathway") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of prolactin signaling pathway") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of prolactin-mediated signaling pathway") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902213") +AnnotationAssertion(rdfs:label "positive regulation of prolactin signaling pathway") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (erythrocyte apoptotic process) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:rl") Annotation( "PMID:14569084") "Any apoptotic process in an erythrocyte.") +AnnotationAssertion( ) +AnnotationAssertion( "rl") +AnnotationAssertion( "2013-06-13T10:02:29Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "RBC apoptotic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "red blood cell apoptotic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "RBC apoptosis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "erythrocyte apoptosis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "red blood cell apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902217") +AnnotationAssertion(rdfs:label "erythrocyte apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses( ObjectSomeValuesFrom( )) + +# Class: (regulation of erythrocyte apoptotic process) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:rl") Annotation( "PMID:14569084") "Any process that modulates the frequency, rate or extent of erythrocyte apoptotic process.") +AnnotationAssertion( "rl") +AnnotationAssertion( "2013-06-20T19:30:53Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of RBC apoptotic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of red blood cell apoptotic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of RBC apoptosis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of erythrocyte apoptosis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of red blood cell apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902250") +AnnotationAssertion(rdfs:label "regulation of erythrocyte apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of erythrocyte apoptotic process) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:rl") Annotation( "PMID:14569084") "Any process that stops, prevents or reduces the frequency, rate or extent of erythrocyte apoptotic process.") +AnnotationAssertion( ) +AnnotationAssertion( "rl") +AnnotationAssertion( "2013-06-20T19:30:59Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of RBC apoptotic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of erythrocyte apoptotic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of red blood cell apoptotic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of RBC apoptotic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of erythrocyte apoptotic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of red blood cell apoptotic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of RBC apoptotic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of erythrocyte apoptotic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of red blood cell apoptotic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of RBC apoptotic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of red blood cell apoptotic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of RBC apoptosis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of erythrocyte apoptosis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of red blood cell apoptosis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of RBC apoptosis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of erythrocyte apoptosis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of red blood cell apoptosis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of RBC apoptosis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of erythrocyte apoptosis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of red blood cell apoptosis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of RBC apoptosis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of RBC apoptotic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of erythrocyte apoptosis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of erythrocyte apoptotic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of red blood cell apoptosis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of red blood cell apoptotic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of RBC apoptosis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of erythrocyte apoptosis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of red blood cell apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902251") +AnnotationAssertion(rdfs:label "negative regulation of erythrocyte apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses( ObjectSomeValuesFrom( )) + +# Class: (positive regulation of erythrocyte apoptotic process) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:rl") Annotation( "PMID:14569084") "Any process that activates or increases the frequency, rate or extent of erythrocyte apoptotic process.") +AnnotationAssertion( ) +AnnotationAssertion( "rl") +AnnotationAssertion( "2013-06-20T19:31:04Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of RBC apoptotic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of red blood cell apoptotic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of RBC apoptotic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of erythrocyte apoptotic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of red blood cell apoptotic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of RBC apoptotic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of erythrocyte apoptotic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of red blood cell apoptotic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of RBC apoptotic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of erythrocyte apoptotic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of red blood cell apoptotic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of RBC apoptosis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of RBC apoptotic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of erythrocyte apoptosis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of erythrocyte apoptotic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of red blood cell apoptosis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of red blood cell apoptotic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of RBC apoptosis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of erythrocyte apoptosis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of red blood cell apoptosis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of RBC apoptosis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of erythrocyte apoptosis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of red blood cell apoptosis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of RBC apoptosis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of erythrocyte apoptosis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of red blood cell apoptosis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of RBC apoptosis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of erythrocyte apoptosis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of red blood cell apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902252") +AnnotationAssertion(rdfs:label "positive regulation of erythrocyte apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses( ObjectSomeValuesFrom( )) + +# Class: (regulation of apoptotic process involved in outflow tract morphogenesis) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:dph") Annotation( "GOC:mtg_apoptosis") Annotation( "PMID:16839542") "Any process that modulates the frequency, rate or extent of apoptotic process involved in outflow tract morphogenesis.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2013-06-24T19:12:24Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of apoptosis involved in outflow tract morphogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902256") +AnnotationAssertion(rdfs:label "regulation of apoptotic process involved in outflow tract morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of apoptotic process involved in outflow tract morphogenesis) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:dph") Annotation( "GOC:mtg_apoptosis") Annotation( "PMID:16839542") "Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in outflow tract morphogenesis.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2013-06-24T19:12:30Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of apoptotic process involved in outflow tract morphogenesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of apoptotic process involved in outflow tract morphogenesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of apoptotic process involved in outflow tract morphogenesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of apoptosis involved in outflow tract morphogenesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of apoptosis involved in outflow tract morphogenesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of apoptosis involved in outflow tract morphogenesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of apoptosis involved in outflow tract morphogenesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of apoptotic process involved in outflow tract morphogenesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of apoptosis involved in outflow tract morphogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902257") +AnnotationAssertion(rdfs:label "negative regulation of apoptotic process involved in outflow tract morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of apoptotic process involved in outflow tract morphogenesis) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:dph") Annotation( "GOC:mtg_apoptosis") Annotation( "PMID:16839542") "Any process that activates or increases the frequency, rate or extent of apoptotic process involved in outflow tract morphogenesis.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2013-06-24T19:12:42Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of apoptotic process involved in outflow tract morphogenesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of apoptotic process involved in outflow tract morphogenesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of apoptotic process involved in outflow tract morphogenesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of apoptosis involved in outflow tract morphogenesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of apoptotic process involved in outflow tract morphogenesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of apoptosis involved in outflow tract morphogenesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of apoptosis involved in outflow tract morphogenesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of apoptosis involved in outflow tract morphogenesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of apoptosis involved in outflow tract morphogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902258") +AnnotationAssertion(rdfs:label "positive regulation of apoptotic process involved in outflow tract morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (apoptotic process involved in blood vessel morphogenesis) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:dph") Annotation( "GOC:mtg_apoptosis") Annotation( "PMID:16163358") "Any apoptotic process that is involved in blood vessel morphogenesis.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2013-06-25T16:16:00Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "apoptotic cell death involved in patterning of blood vessels") +AnnotationAssertion(Annotation( "GOC:TermGenie") "apoptotic programmed cell death involved in patterning of blood vessels") +AnnotationAssertion(Annotation( "GOC:TermGenie") "programmed cell death by apoptosis involved in patterning of blood vessels") +AnnotationAssertion(Annotation( "GOC:TermGenie") "apoptosis involved in patterning of blood vessels") +AnnotationAssertion(Annotation( "GOC:TermGenie") "apoptotic program involved in patterning of blood vessels") +AnnotationAssertion(Annotation( "GOC:TermGenie") "type I programmed cell death involved in patterning of blood vessels") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "signaling (initiator) caspase activity involved in patterning of blood vessels") +AnnotationAssertion( "GO:1902262") +AnnotationAssertion(rdfs:label "apoptotic process involved in blood vessel morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of chromatin organization) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:bf") Annotation( "GOC:vw") Annotation( "GO_REF:0000058") Annotation( "PMID:18314879") "Any process that modulates the frequency, rate or extent of chromatin organization.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2013-07-01T13:21:52Z") +AnnotationAssertion( "GO:0001672") +AnnotationAssertion( "GO:1903308") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of chromatin organisation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of establishment or maintenance of chromatin architecture") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "regulation of chromatin assembly or disassembly") +AnnotationAssertion( "regulation of chromatin assembly/disassembly") +AnnotationAssertion( "regulation of chromatin modification") +AnnotationAssertion( "GO:1902275") +AnnotationAssertion(rdfs:label "regulation of chromatin organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of sodium ion transmembrane transport) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:mtg_cardiac_conduct_nov11") Annotation( "GOC:rl") Annotation( "PMID:18591664") "Any process that modulates the frequency, rate or extent of sodium ion transmembrane transport.") +AnnotationAssertion( "rl") +AnnotationAssertion( "2013-07-18T13:33:53Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of sodium ion membrane transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902305") +AnnotationAssertion(rdfs:label "regulation of sodium ion transmembrane transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of sodium ion transmembrane transport) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:mtg_cardiac_conduct_nov11") Annotation( "GOC:rl") Annotation( "PMID:18591664") "Any process that stops, prevents or reduces the frequency, rate or extent of sodium ion transmembrane transport.") +AnnotationAssertion( "rl") +AnnotationAssertion( "2013-07-18T13:34:01Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of sodium ion membrane transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of sodium ion transmembrane transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of sodium ion membrane transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of sodium ion transmembrane transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of sodium ion membrane transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of sodium ion transmembrane transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of sodium ion membrane transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of sodium ion membrane transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of sodium ion transmembrane transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902306") +AnnotationAssertion(rdfs:label "negative regulation of sodium ion transmembrane transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of sodium ion transmembrane transport) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:mtg_cardiac_conduct_nov11") Annotation( "GOC:rl") Annotation( "PMID:18591664") "Any process that activates or increases the frequency, rate or extent of sodium ion transmembrane transport.") +AnnotationAssertion( "rl") +AnnotationAssertion( "2013-07-18T13:34:18Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of sodium ion membrane transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of sodium ion membrane transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of sodium ion transmembrane transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of sodium ion membrane transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of sodium ion transmembrane transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of sodium ion membrane transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of sodium ion transmembrane transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of sodium ion membrane transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of sodium ion transmembrane transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902307") +AnnotationAssertion(rdfs:label "positive regulation of sodium ion transmembrane transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of apoptotic process involved in morphogenesis) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:sart") Annotation( "PMID:12202035") "Any process that modulates the frequency, rate or extent of apoptotic process involved in morphogenesis.") +AnnotationAssertion( "sart") +AnnotationAssertion( "2013-07-29T15:03:16Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of apoptosis involved in morphogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of apoptosis involved in development") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of morphogenetic apoptosis") +AnnotationAssertion( "GO:1902337") +AnnotationAssertion(rdfs:label "regulation of apoptotic process involved in morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of apoptotic process involved in morphogenesis) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:sart") Annotation( "PMID:12202035") "Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in morphogenesis.") +AnnotationAssertion( "sart") +AnnotationAssertion( "2013-07-29T15:03:25Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of apoptotic process involved in morphogenesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of apoptotic process involved in morphogenesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of apoptotic process involved in morphogenesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of apoptosis involved in morphogenesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of apoptosis involved in morphogenesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of apoptosis involved in morphogenesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of apoptosis involved in morphogenesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of apoptotic process involved in morphogenesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of apoptosis involved in morphogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of apoptosis involved in development") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of morphogenetic apoptosis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of apoptosis involved in development") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of morphogenetic apoptosis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of apoptosis involved in development") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of morphogenetic apoptosis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of apoptosis involved in development") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of morphogenetic apoptosis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of apoptosis involved in development") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of morphogenetic apoptosis") +AnnotationAssertion( "GO:1902338") +AnnotationAssertion(rdfs:label "negative regulation of apoptotic process involved in morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of apoptotic process involved in morphogenesis) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:sart") Annotation( "PMID:12202035") "Any process that activates or increases the frequency, rate or extent of apoptotic process involved in morphogenesis.") +AnnotationAssertion( "sart") +AnnotationAssertion( "2013-07-29T15:03:33Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of apoptotic process involved in morphogenesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of apoptotic process involved in morphogenesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of apoptotic process involved in morphogenesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of apoptosis involved in morphogenesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of apoptotic process involved in morphogenesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of apoptosis involved in morphogenesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of apoptosis involved in morphogenesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of apoptosis involved in morphogenesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of apoptosis involved in morphogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of apoptosis involved in development") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of morphogenetic apoptosis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of apoptosis involved in development") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of morphogenetic apoptosis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of apoptosis involved in development") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of morphogenetic apoptosis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of apoptosis involved in development") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of morphogenetic apoptosis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of apoptosis involved in development") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of morphogenetic apoptosis") +AnnotationAssertion( "GO:1902339") +AnnotationAssertion(rdfs:label "positive regulation of apoptotic process involved in morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of chromosome condensation) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "PMID:23219725") "Any process that stops, prevents or reduces the frequency, rate or extent of chromosome condensation.") +AnnotationAssertion( "dgf") +AnnotationAssertion( "2013-07-29T20:54:14Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of chromosome condensation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of eukaryotic chromosome condensation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of nuclear chromosome condensation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of chromosome condensation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of eukaryotic chromosome condensation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of nuclear chromosome condensation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of chromosome condensation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of eukaryotic chromosome condensation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of nuclear chromosome condensation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of eukaryotic chromosome condensation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of nuclear chromosome condensation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of chromosome condensation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of eukaryotic chromosome condensation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of nuclear chromosome condensation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902340") +AnnotationAssertion(rdfs:label "negative regulation of chromosome condensation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (sulfate transmembrane transport) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:dph") Annotation( "PMID:9055073") "The directed movement of sulfate across a membrane.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2013-08-14T14:46:04Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902358") +AnnotationAssertion(rdfs:label "sulfate transmembrane transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (melanocyte apoptotic process) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:ic") Annotation( "PMID:20530876") "Any apoptotic process in a melanocyte, the main structural component of the epidermis.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2013-08-15T16:35:45Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "melanocyte apoptosis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "melanophore apoptosis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "melanophore apoptotic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902362") +AnnotationAssertion(rdfs:label "melanocyte apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (negative regulation of RNA catabolic process) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:bf") Annotation( "PMID:16640457") "Any process that stops, prevents or reduces the frequency, rate or extent of RNA catabolic process.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2013-08-22T14:59:39Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of RNA breakdown") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of RNA catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of RNA catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of RNA degradation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of RNA breakdown") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of RNA catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of RNA catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of RNA degradation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of RNA breakdown") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of RNA catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of RNA catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of RNA degradation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of RNA breakdown") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of RNA catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of RNA degradation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of RNA breakdown") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of RNA catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of RNA catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of RNA degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902369") +AnnotationAssertion(rdfs:label "negative regulation of RNA catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (protein localization to bicellular tight junction) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "PMID:18332111") "A process in which a protein is transported to, or maintained in, a location within a bicellular tight junction.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2013-09-11T21:43:13Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "protein localisation in tight junction") +AnnotationAssertion(Annotation( "GOC:TermGenie") "protein localisation to tight junction") +AnnotationAssertion(Annotation( "GOC:TermGenie") "protein localization in tight junction") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902396") +AnnotationAssertion(rdfs:label "protein localization to bicellular tight junction") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (protein localization to cell junction) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "PMID:18332111") "A process in which a protein is transported to, or maintained in, a location within a cell junction.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2013-09-13T16:55:57Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "protein localisation in cell junction") +AnnotationAssertion(Annotation( "GOC:TermGenie") "protein localisation to cell junction") +AnnotationAssertion(Annotation( "GOC:TermGenie") "protein localization in cell junction") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902414") +AnnotationAssertion(rdfs:label "protein localization to cell junction") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (sulfate import across plasma membrane) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "PMID:14723223") "The directed movement of sulfate from outside of a cell, across the plasma membrane and into the cytosol.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2013-10-07T14:12:38Z") +AnnotationAssertion( "sulfate import into cell") +AnnotationAssertion( "sulphate import into cell") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902434") +AnnotationAssertion(rdfs:label "sulfate import across plasma membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of stem cell population maintenance) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:hjd") Annotation( "PMID:22969033") "Any process that stops, prevents or reduces the frequency, rate or extent of stem cell population maintenance.") +AnnotationAssertion( "cjm") +AnnotationAssertion( "2013-10-16T22:19:17Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of stem cell maintenance") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of stem cell maintenance") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of stem cell maintenance") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of stem cell maintenance") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of maintenance of pluripotency") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of maintenance of pluripotency") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of maintenance of pluripotency") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of maintenance of pluripotency") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of maintenance of pluripotency") +AnnotationAssertion( "GO:1902455") +AnnotationAssertion(rdfs:label "negative regulation of stem cell population maintenance") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of stem cell population maintenance) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:hjd") Annotation( "PMID:22969033") "Any process that activates or increases the frequency, rate or extent of stem cell population maintenance.") +AnnotationAssertion( "cjm") +AnnotationAssertion( "2013-10-16T22:27:47Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of stem cell maintenance") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of stem cell maintenance") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of stem cell maintenance") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of stem cell maintenance") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of maintenance of pluripotency") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of maintenance of pluripotency") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of maintenance of pluripotency") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of maintenance of pluripotency") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of maintenance of pluripotency") +AnnotationAssertion( "GO:1902459") +AnnotationAssertion(rdfs:label "positive regulation of stem cell population maintenance") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (protein localization to cell leading edge) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:lb") Annotation( "PMID:21543326") "A process in which a protein is transported to, or maintained in, a location within a cell leading edge.") +AnnotationAssertion( "jl") +AnnotationAssertion( "2013-10-22T12:36:07Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "protein localisation in cell leading edge") +AnnotationAssertion(Annotation( "GOC:TermGenie") "protein localisation to cell leading edge") +AnnotationAssertion(Annotation( "GOC:TermGenie") "protein localization in cell leading edge") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902463") +AnnotationAssertion(rdfs:label "protein localization to cell leading edge") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of protein localization to synapse) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:kmv") Annotation( "PMID:22588719") "Any process that modulates the frequency, rate or extent of protein localization to synapse.") +AnnotationAssertion( "kmv") +AnnotationAssertion( "2013-10-25T15:09:09Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of protein localisation to synapse") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902473") +AnnotationAssertion(rdfs:label "regulation of protein localization to synapse") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of protein localization to synapse) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:kmv") Annotation( "PMID:22588719") "Any process that activates or increases the frequency, rate or extent of protein localization to synapse.") +AnnotationAssertion( "kmv") +AnnotationAssertion( "2013-10-25T15:09:18Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of protein localisation to synapse") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of protein localisation to synapse") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of protein localization to synapse") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of protein localisation to synapse") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of protein localization to synapse") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of protein localisation to synapse") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of protein localization to synapse") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of protein localisation to synapse") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of protein localization to synapse") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902474") +AnnotationAssertion(rdfs:label "positive regulation of protein localization to synapse") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (L-alpha-amino acid transmembrane transport) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:kmv") Annotation( "PMID:14668347") "The directed movement of L-alpha-amino acid across a membrane.") +AnnotationAssertion( "kmv") +AnnotationAssertion( "2013-10-25T15:17:39Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902475") +AnnotationAssertion(rdfs:label "L-alpha-amino acid transmembrane transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (Sertoli cell apoptotic process) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:ic") Annotation( "PMID:17761895") "Any apoptotic process in a Sertoli cell.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2013-11-06T11:27:34Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "Sertoli cell apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902484") +AnnotationAssertion(rdfs:label "Sertoli cell apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (cholangiocyte apoptotic process) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "PMID:22961800") "Any apoptotic process in a cholangiocyte.") +AnnotationAssertion( "cls") +AnnotationAssertion( "2013-11-12T15:30:08Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "epithelial cell of bile duct apoptotic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "cholangiocyte apoptosis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "epithelial cell of bile duct apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902488") +AnnotationAssertion(rdfs:label "cholangiocyte apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (hepatoblast apoptotic process) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "PMID:22412967") "Any apoptotic process in a hepatoblast.") +AnnotationAssertion( "cls") +AnnotationAssertion( "2013-11-12T17:02:52Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "hepatoblast apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902489") +AnnotationAssertion(rdfs:label "hepatoblast apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of sperm capacitation) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:hjd") Annotation( "PMID:22539676") "Any process that modulates the frequency, rate or extent of sperm capacitation.") +AnnotationAssertion( "hjd") +AnnotationAssertion( "2013-11-12T21:17:03Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of sperm activation") +AnnotationAssertion( "GO:1902490") +AnnotationAssertion(rdfs:label "regulation of sperm capacitation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of sperm capacitation) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:hjd") Annotation( "PMID:22539676") "Any process that stops, prevents or reduces the frequency, rate or extent of sperm capacitation.") +AnnotationAssertion( "hjd") +AnnotationAssertion( "2013-11-12T21:17:12Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of sperm capacitation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of sperm capacitation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of sperm capacitation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of sperm capacitation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of sperm activation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of sperm activation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of sperm activation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of sperm activation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of sperm activation") +AnnotationAssertion( "GO:1902491") +AnnotationAssertion(rdfs:label "negative regulation of sperm capacitation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of sperm capacitation) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:hjd") Annotation( "PMID:22539676") "Any process that activates or increases the frequency, rate or extent of sperm capacitation.") +AnnotationAssertion( "hjd") +AnnotationAssertion( "2013-11-12T21:17:21Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of sperm capacitation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of sperm capacitation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of sperm capacitation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of sperm capacitation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of sperm activation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of sperm activation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of sperm activation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of sperm activation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of sperm activation") +AnnotationAssertion( "GO:1902492") +AnnotationAssertion(rdfs:label "positive regulation of sperm capacitation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (catalytic complex) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:bhm") Annotation( "PMID:8077207") "A protein complex which is capable of catalytic activity.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/19980"^^xsd:anyURI) +AnnotationAssertion( "bhm") +AnnotationAssertion( "2013-11-13T16:18:47Z") +AnnotationAssertion(Annotation( "GOC:bhm") Annotation( "GOC:jl") "enzyme complex") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:1902494") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "catalytic complex") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (transmembrane transporter complex) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:bhm") Annotation( "PMID:18024586") "A transmembrane protein complex which enables the transfer of a substance from one side of a membrane to the other.") +AnnotationAssertion( "bhm") +AnnotationAssertion( "2013-11-13T16:23:04Z") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:1902495") +AnnotationAssertion(rdfs:label "transmembrane transporter complex") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (regulation of apoptotic DNA fragmentation) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:hjd") Annotation( "PMID:15572351") Annotation( "PMID:15723341") "Any process that modulates the frequency, rate or extent of apoptotic DNA fragmentation.") +AnnotationAssertion( "hjd") +AnnotationAssertion( "2013-11-15T18:28:32Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of DNA fragmentation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of chromatinolysis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of DNA catabolic process during apoptosis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of DNA catabolism during apoptosis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of DNA fragmentation involved in apoptotic nuclear change") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of endonucleolytic DNA catabolic process involved in apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902510") +AnnotationAssertion(rdfs:comment "DNA fragmentation in response to apoptotic signals is achieved through the activity of apoptotic nucleases (see GO:0006309 'apoptotic DNA fragmentation'). Gene products involved in compartmentalization of such nucleases and in activation or repression of their enzymatic activity should be annotated to the regulation term GO:1902510 'regulation of apoptotic DNA fragmentation' or to one of its children (see PMID:15723341).") +AnnotationAssertion(rdfs:label "regulation of apoptotic DNA fragmentation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of apoptotic DNA fragmentation) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:hjd") Annotation( "PMID:15572351") "Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic DNA fragmentation.") +AnnotationAssertion( "hjd") +AnnotationAssertion( "2013-11-15T18:28:41Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of DNA catabolic process during apoptosis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of DNA catabolism during apoptosis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of DNA fragmentation involved in apoptotic nuclear change") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of apoptotic DNA fragmentation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of endonucleolytic DNA catabolic process involved in apoptosis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of DNA catabolic process during apoptosis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of DNA catabolism during apoptosis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of DNA fragmentation involved in apoptotic nuclear change") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of apoptotic DNA fragmentation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of endonucleolytic DNA catabolic process involved in apoptosis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of DNA catabolic process during apoptosis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of DNA catabolism during apoptosis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of DNA fragmentation involved in apoptotic nuclear change") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of apoptotic DNA fragmentation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of endonucleolytic DNA catabolic process involved in apoptosis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of DNA catabolic process during apoptosis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of DNA catabolism during apoptosis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of DNA fragmentation involved in apoptotic nuclear change") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of endonucleolytic DNA catabolic process involved in apoptosis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of DNA catabolic process during apoptosis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of DNA catabolism during apoptosis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of DNA fragmentation involved in apoptotic nuclear change") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of apoptotic DNA fragmentation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of endonucleolytic DNA catabolic process involved in apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902511") +AnnotationAssertion(rdfs:label "negative regulation of apoptotic DNA fragmentation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of apoptotic DNA fragmentation) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:hjd") Annotation( "PMID:15572351") "Any process that activates or increases the frequency, rate or extent of apoptotic DNA fragmentation.") +AnnotationAssertion( "hjd") +AnnotationAssertion( "2013-11-15T18:28:50Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of DNA catabolic process during apoptosis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of DNA catabolism during apoptosis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of DNA fragmentation involved in apoptotic nuclear change") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of endonucleolytic DNA catabolic process involved in apoptosis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of DNA catabolic process during apoptosis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of DNA catabolism during apoptosis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of DNA fragmentation involved in apoptotic nuclear change") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of apoptotic DNA fragmentation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of endonucleolytic DNA catabolic process involved in apoptosis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of DNA catabolic process during apoptosis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of DNA catabolism during apoptosis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of DNA fragmentation involved in apoptotic nuclear change") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of apoptotic DNA fragmentation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of endonucleolytic DNA catabolic process involved in apoptosis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of DNA catabolic process during apoptosis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of DNA catabolism during apoptosis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of DNA fragmentation involved in apoptotic nuclear change") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of apoptotic DNA fragmentation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of endonucleolytic DNA catabolic process involved in apoptosis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of DNA catabolic process during apoptosis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of DNA catabolism during apoptosis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of DNA fragmentation involved in apoptotic nuclear change") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of apoptotic DNA fragmentation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of endonucleolytic DNA catabolic process involved in apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902512") +AnnotationAssertion(rdfs:label "positive regulation of apoptotic DNA fragmentation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of organelle transport along microtubule) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:dph") Annotation( "PMID:21147087") "Any process that modulates the frequency, rate or extent of organelle transport along microtubule.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2013-11-15T20:15:17Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of microtubule-based organelle localization") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902513") +AnnotationAssertion(rdfs:label "regulation of organelle transport along microtubule") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of intracellular signal transduction) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:dph") Annotation( "GOC:signaling") Annotation( "GOC:tb") "Any process that modulates the frequency, rate or extent of intracellular signal transduction.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2013-12-02T11:32:52Z") +AnnotationAssertion( "GO:0010627") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of intracellular signaling cascade") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of intracellular signaling chain") +AnnotationAssertion( "regulation of intracellular protein kinase cascade") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of intracellular signal transduction pathway") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of signal transmission via intracellular cascade") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of intracellular signaling pathway") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of signal transduction via intracellular signaling cascade") +AnnotationAssertion( "GO:1902531") +AnnotationAssertion(rdfs:label "regulation of intracellular signal transduction") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of intracellular signal transduction) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:dph") Annotation( "GOC:signaling") Annotation( "GOC:tb") "Any process that stops, prevents or reduces the frequency, rate or extent of intracellular signal transduction.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2013-12-02T11:33:01Z") +AnnotationAssertion( "GO:0010741") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of intracellular signal transduction") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of intracellular signaling chain") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of intracellular signal transduction") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of intracellular signaling chain") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of intracellular signal transduction") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of intracellular signaling chain") +AnnotationAssertion( "negative regulation of intracellular protein kinase cascade") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of intracellular signaling cascade") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of intracellular signaling chain") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of intracellular signal transduction pathway") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of intracellular signaling cascade") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of signal transmission via intracellular cascade") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of intracellular signal transduction pathway") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of intracellular signal transduction pathway") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of intracellular signaling cascade") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of signal transmission via intracellular cascade") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of intracellular signal transduction") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of intracellular signal transduction pathway") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of intracellular signaling cascade") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of intracellular signaling chain") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of signal transmission via intracellular cascade") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of intracellular signal transduction pathway") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of signal transmission via intracellular cascade") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of intracellular signaling pathway") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of signal transduction via intracellular signaling cascade") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of intracellular signaling cascade") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of intracellular signaling pathway") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of signal transduction via intracellular signaling cascade") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of signal transmission via intracellular cascade") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of intracellular signaling pathway") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of signal transduction via intracellular signaling cascade") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of intracellular signaling pathway") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of signal transduction via intracellular signaling cascade") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of intracellular signaling pathway") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of signal transduction via intracellular signaling cascade") +AnnotationAssertion( "GO:1902532") +AnnotationAssertion(rdfs:label "negative regulation of intracellular signal transduction") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of intracellular signal transduction) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:dph") Annotation( "GOC:signaling") Annotation( "GOC:tb") "Any process that activates or increases the frequency, rate or extent of intracellular signal transduction.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2013-12-02T11:33:10Z") +AnnotationAssertion( "GO:0010740") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of intracellular signaling chain") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of intracellular signal transduction") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of intracellular signaling chain") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of intracellular signal transduction") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of intracellular signaling chain") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of intracellular signal transduction") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of intracellular signaling chain") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of intracellular signal transduction") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of intracellular signal transduction pathway") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of intracellular signaling cascade") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of intracellular signaling chain") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of signal transmission via intracellular cascade") +AnnotationAssertion( "positive regulation of intracellular protein kinase cascade") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of intracellular signal transduction pathway") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of signal transmission via intracellular cascade") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of intracellular signal transduction pathway") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of signal transmission via intracellular cascade") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of intracellular signal transduction pathway") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of signal transmission via intracellular cascade") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of intracellular signal transduction pathway") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of signal transmission via intracellular cascade") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of intracellular signaling pathway") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of signal transduction via intracellular signaling cascade") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of intracellular signaling cascade") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of intracellular signaling pathway") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of signal transduction via intracellular signaling cascade") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of intracellular signaling cascade") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of intracellular signaling pathway") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of signal transduction via intracellular signaling cascade") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of intracellular signaling cascade") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of intracellular signaling pathway") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of signal transduction via intracellular signaling cascade") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of intracellular signaling cascade") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of intracellular signaling pathway") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of signal transduction via intracellular signaling cascade") +AnnotationAssertion( "GO:1902533") +AnnotationAssertion(rdfs:label "positive regulation of intracellular signal transduction") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of neutrophil activation) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "PMID:17588661") "Any process that modulates the frequency, rate or extent of neutrophil activation.") +AnnotationAssertion( "ecu") +AnnotationAssertion( "2013-12-10T15:33:08Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902563") +AnnotationAssertion(rdfs:label "regulation of neutrophil activation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of neutrophil activation) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "PMID:17588661") "Any process that stops, prevents or reduces the frequency, rate or extent of neutrophil activation.") +AnnotationAssertion( "ecu") +AnnotationAssertion( "2013-12-10T15:33:16Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of neutrophil activation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of neutrophil activation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of neutrophil activation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of neutrophil activation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902564") +AnnotationAssertion(rdfs:label "negative regulation of neutrophil activation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of neutrophil activation) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "PMID:17588661") "Any process that activates or increases the frequency, rate or extent of neutrophil activation.") +AnnotationAssertion( "ecu") +AnnotationAssertion( "2013-12-10T15:33:26Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of neutrophil activation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of neutrophil activation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of neutrophil activation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of neutrophil activation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902565") +AnnotationAssertion(rdfs:label "positive regulation of neutrophil activation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (protein localization to nucleolus) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "PMID:22809626") "A process in which a protein is transported to, or maintained in, a location within a nucleolus.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2013-12-10T16:25:28Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "protein localisation in nucleolus") +AnnotationAssertion(Annotation( "GOC:TermGenie") "protein localisation to nucleolus") +AnnotationAssertion(Annotation( "GOC:TermGenie") "protein localization in nucleolus") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902570") +AnnotationAssertion(rdfs:label "protein localization to nucleolus") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of response to water deprivation) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:24198318") "Any process that activates or increases the frequency, rate or extent of response to water deprivation.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2013-12-19T00:31:58Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of response to dehydration") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of response to drought") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of response to thirst") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of response to dehydration") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of response to drought") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of response to thirst") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of response to water deprivation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of response to dehydration") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of response to drought") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of response to thirst") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of response to water deprivation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of response to dehydration") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of response to drought") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of response to thirst") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of response to water deprivation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of response to dehydration") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of response to drought") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of response to thirst") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of response to water deprivation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of drought tolerance") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of drought tolerance") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of drought tolerance") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of drought tolerance") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of drought tolerance") +AnnotationAssertion( "GO:1902584") +AnnotationAssertion(rdfs:label "positive regulation of response to water deprivation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of neutrophil migration) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:1826836") "Any process that modulates the frequency, rate or extent of neutrophil migration.") +AnnotationAssertion( "sl") +AnnotationAssertion( "2014-01-15T18:58:39Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902622") +AnnotationAssertion(rdfs:label "regulation of neutrophil migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of neutrophil migration) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:1826836") "Any process that stops, prevents or reduces the frequency, rate or extent of neutrophil migration.") +AnnotationAssertion( "sl") +AnnotationAssertion( "2014-01-15T18:58:49Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of neutrophil migration") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of neutrophil migration") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of neutrophil migration") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of neutrophil migration") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902623") +AnnotationAssertion(rdfs:label "negative regulation of neutrophil migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of neutrophil migration) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:1826836") "Any process that activates or increases the frequency, rate or extent of neutrophil migration.") +AnnotationAssertion( "sl") +AnnotationAssertion( "2014-01-15T18:58:58Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of neutrophil migration") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of neutrophil migration") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of neutrophil migration") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of neutrophil migration") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902624") +AnnotationAssertion(rdfs:label "positive regulation of neutrophil migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (neural crest cell differentiation involved in thymus development) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:nhn") Annotation( "GO_REF:0000060") Annotation( "PMID:15741317") Annotation( "PMID:18292542") "Any neural crest cell differentiation that is involved in thymus development.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2014-01-21T10:03:20Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902637") +AnnotationAssertion(rdfs:label "neural crest cell differentiation involved in thymus development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (neural crest cell differentiation involved in parathyroid gland development) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:nhn") Annotation( "GO_REF:0000060") Annotation( "PMID:15741317") "Any neural crest cell differentiation that is involved in parathyroid gland development.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2014-01-21T10:03:29Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902638") +AnnotationAssertion(rdfs:label "neural crest cell differentiation involved in parathyroid gland development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (carbon dioxide binding) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:bhm") Annotation( "GO_REF:0000067") Annotation( "PMID:15491402") "Binding to carbon dioxide.") +AnnotationAssertion( "bhm") +AnnotationAssertion( "2014-02-04T10:38:41Z") +AnnotationAssertion( "CO2 binding") +AnnotationAssertion( "molecular_function") +AnnotationAssertion( "GO:1902670") +AnnotationAssertion(rdfs:label "carbon dioxide binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of RNA biosynthetic process) + +AnnotationAssertion(Annotation( "GO:jl") Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") "Any process that stops, prevents or reduces the frequency, rate or extent of RNA biosynthetic process.") +AnnotationAssertion( "jl") +AnnotationAssertion( "2014-02-05T16:32:01Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of RNA anabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of RNA biosynthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of RNA biosynthetic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of RNA formation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of RNA synthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of RNA anabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of RNA biosynthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of RNA biosynthetic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of RNA formation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of RNA synthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of RNA anabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of RNA biosynthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of RNA biosynthetic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of RNA formation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of RNA synthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of RNA anabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of RNA biosynthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of RNA formation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of RNA synthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of RNA anabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of RNA biosynthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of RNA biosynthetic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of RNA formation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of RNA synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902679") +AnnotationAssertion(rdfs:label "negative regulation of RNA biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of RNA biosynthetic process) + +AnnotationAssertion(Annotation( "GO:jl") Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") "Any process that activates or increases the frequency, rate or extent of RNA biosynthetic process.") +AnnotationAssertion( "jl") +AnnotationAssertion( "2014-02-05T16:32:10Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of RNA anabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of RNA biosynthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of RNA formation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of RNA synthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of RNA anabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of RNA biosynthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of RNA biosynthetic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of RNA formation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of RNA synthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of RNA anabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of RNA biosynthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of RNA biosynthetic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of RNA formation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of RNA synthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of RNA anabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of RNA biosynthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of RNA biosynthetic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of RNA formation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of RNA synthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of RNA anabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of RNA biosynthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of RNA biosynthetic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of RNA formation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of RNA synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902680") +AnnotationAssertion(rdfs:label "positive regulation of RNA biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of receptor localization to synapse) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:kmv") Annotation( "GO_REF:0000058") Annotation( "PMID:22252129") "Any process that modulates the frequency, rate or extent of receptor localization to synapse.") +AnnotationAssertion( "kmv") +AnnotationAssertion( "2014-02-07T17:38:31Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of receptor localisation to synapse") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902683") +AnnotationAssertion(rdfs:label "regulation of receptor localization to synapse") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of receptor localization to synapse) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:kmv") Annotation( "GO_REF:0000058") Annotation( "PMID:22252129") "Any process that stops, prevents or reduces the frequency, rate or extent of receptor localization to synapse.") +AnnotationAssertion( "kmv") +AnnotationAssertion( "2014-02-07T17:38:41Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of receptor localisation to synapse") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of receptor localization to synapse") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of receptor localisation to synapse") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of receptor localization to synapse") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of receptor localisation to synapse") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of receptor localization to synapse") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of receptor localisation to synapse") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of receptor localisation to synapse") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of receptor localization to synapse") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902684") +AnnotationAssertion(rdfs:label "negative regulation of receptor localization to synapse") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of receptor localization to synapse) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:kmv") Annotation( "GO_REF:0000058") Annotation( "PMID:22252129") "Any process that activates or increases the frequency, rate or extent of receptor localization to synapse.") +AnnotationAssertion( "kmv") +AnnotationAssertion( "2014-02-07T17:38:51Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of receptor localisation to synapse") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of receptor localisation to synapse") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of receptor localization to synapse") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of receptor localisation to synapse") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of receptor localization to synapse") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of receptor localisation to synapse") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of receptor localization to synapse") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of receptor localisation to synapse") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of receptor localization to synapse") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902685") +AnnotationAssertion(rdfs:label "positive regulation of receptor localization to synapse") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of neuroblast proliferation) + +AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "GO_REF:0000058") Annotation( "PMID:21168496") "Any process that modulates the frequency, rate or extent of neuroblast proliferation.") +AnnotationAssertion( "rl") +AnnotationAssertion( "2014-02-18T10:03:31Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902692") +AnnotationAssertion(rdfs:label "regulation of neuroblast proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (pentose catabolic process to butyrate) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mengo_curators") Annotation( "GO_REF:0000093") Annotation( "PMID:18727018") Annotation( "PMID:19539744") "The chemical reactions and pathways resulting in the breakdown of pentose to butyrate.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2014-02-19T18:28:28Z") +AnnotationAssertion( "GO:1990288") +AnnotationAssertion(Annotation( "GOC:tt") "acidogenesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "pentose breakdown to butyrate") +AnnotationAssertion(Annotation( "GOC:TermGenie") "pentose catabolism to butyrate") +AnnotationAssertion(Annotation( "GOC:TermGenie") "pentose degradation to butyrate") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902698") +AnnotationAssertion(rdfs:label "pentose catabolic process to butyrate") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (pentose catabolic process to acetate) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mengo_curators") Annotation( "GO_REF:0000093") Annotation( "PMID:18727018") Annotation( "PMID:19539744") "The chemical reactions and pathways resulting in the breakdown of pentose to acetate.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2014-02-19T18:28:38Z") +AnnotationAssertion( "GO:1990289") +AnnotationAssertion(Annotation( "GOC:tt") "acidogenesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "pentose breakdown to acetate") +AnnotationAssertion(Annotation( "GOC:TermGenie") "pentose catabolism to acetate") +AnnotationAssertion(Annotation( "GOC:TermGenie") "pentose degradation to acetate") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902699") +AnnotationAssertion(rdfs:label "pentose catabolic process to acetate") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) + +# Class: (GABA receptor complex) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:bhm") Annotation( "GO_REF:0000088") Annotation( "PMID:18790874") "A protein complex which is capable of GABA receptor activity. Upon binding of gamma-aminobutyric acid (GABA) it transmits the signal from one side of the membrane to the other to initiate a change in cell activity. Major inhibitory receptor in vertebrate brain. Also found in other vertebrate tissues, invertebrates and possibly in plants. Effective benzodiazepine receptor.") +AnnotationAssertion( "bhm") +AnnotationAssertion( "2014-02-20T16:07:48Z") +AnnotationAssertion( "gamma-aminobutyric acid receptor complex") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:1902710") +AnnotationAssertion(rdfs:label "GABA receptor complex") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of prolactin secretion) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:16159377") "Any process that stops, prevents or reduces the frequency, rate or extent of prolactin secretion.") +AnnotationAssertion( "mr") +AnnotationAssertion( "2014-02-24T16:09:28Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of prolactin secretion") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of prolactin secretion") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of prolactin secretion") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of prolactin secretion") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902721") +AnnotationAssertion(rdfs:label "negative regulation of prolactin secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of prolactin secretion) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:16159377") "Any process that activates or increases the frequency, rate or extent of prolactin secretion.") +AnnotationAssertion( "mr") +AnnotationAssertion( "2014-02-24T16:09:37Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of prolactin secretion") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of prolactin secretion") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of prolactin secretion") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of prolactin secretion") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902722") +AnnotationAssertion(rdfs:label "positive regulation of prolactin secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of proteoglycan biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:23212449") "Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans.") +AnnotationAssertion( "mr") +AnnotationAssertion( "2014-02-24T16:10:43Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of proteoglycan anabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of proteoglycan biosynthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of proteoglycan biosynthetic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of proteoglycan formation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of proteoglycan synthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of proteoglycan anabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of proteoglycan biosynthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of proteoglycan biosynthetic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of proteoglycan formation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of proteoglycan synthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of proteoglycan anabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of proteoglycan biosynthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of proteoglycan biosynthetic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of proteoglycan formation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of proteoglycan synthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of proteoglycan anabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of proteoglycan biosynthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of proteoglycan formation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of proteoglycan synthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of proteoglycan anabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of proteoglycan biosynthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of proteoglycan biosynthetic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of proteoglycan formation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of proteoglycan synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902729") +AnnotationAssertion(rdfs:label "negative regulation of proteoglycan biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of proteoglycan biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:23212449") "Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans.") +AnnotationAssertion( "mr") +AnnotationAssertion( "2014-02-24T16:10:52Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of proteoglycan anabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of proteoglycan biosynthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of proteoglycan formation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of proteoglycan synthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of proteoglycan anabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of proteoglycan biosynthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of proteoglycan biosynthetic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of proteoglycan formation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of proteoglycan synthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of proteoglycan anabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of proteoglycan biosynthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of proteoglycan biosynthetic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of proteoglycan formation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of proteoglycan synthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of proteoglycan anabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of proteoglycan biosynthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of proteoglycan biosynthetic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of proteoglycan formation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of proteoglycan synthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of proteoglycan anabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of proteoglycan biosynthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of proteoglycan biosynthetic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of proteoglycan formation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of proteoglycan synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902730") +AnnotationAssertion(rdfs:label "positive regulation of proteoglycan biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of growth plate cartilage chondrocyte differentiation) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:23212449") "Any process that modulates the rate, frequency, or extent of the process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte that will contribute to the growth of a bone. A chondrocyte is a polymorphic cell that forms cartilage.") +AnnotationAssertion( "mr") +AnnotationAssertion( "2014-02-24T16:11:28Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902733") +AnnotationAssertion(rdfs:label "regulation of growth plate cartilage chondrocyte differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of chondrocyte differentiation involved in endochondral bone morphogenesis) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:8662546") "Any process that modulates the rate, frequency, or extent of the process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte that will contribute to the development of a bone. A chondrocyte is a polymorphic cell that forms cartilage.") +AnnotationAssertion( "mr") +AnnotationAssertion( "2014-02-26T15:36:15Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902738") +AnnotationAssertion(rdfs:label "regulation of chondrocyte differentiation involved in endochondral bone morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (apoptotic process involved in development) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:pg") Annotation( "GO_REF:0000060") "Any apoptotic process that is involved in anatomical structure development.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2014-02-28T13:09:43Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "apoptotic cell death involved in anatomical structure development") +AnnotationAssertion(Annotation( "GOC:TermGenie") "apoptotic cell death involved in development of an anatomical structure") +AnnotationAssertion( "apoptotic process involved in anatomical structure development") +AnnotationAssertion(Annotation( "GOC:TermGenie") "apoptotic process involved in development of an anatomical structure") +AnnotationAssertion(Annotation( "GOC:TermGenie") "apoptotic programmed cell death involved in anatomical structure development") +AnnotationAssertion(Annotation( "GOC:TermGenie") "apoptotic programmed cell death involved in development of an anatomical structure") +AnnotationAssertion(Annotation( "GOC:TermGenie") "programmed cell death by apoptosis involved in anatomical structure development") +AnnotationAssertion(Annotation( "GOC:TermGenie") "programmed cell death by apoptosis involved in development of an anatomical structure") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of apoptosis involved in anatomical structure development") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of apoptosis involved in development of an anatomical structure") +AnnotationAssertion(Annotation( "GOC:TermGenie") "apoptosis involved in anatomical structure development") +AnnotationAssertion(Annotation( "GOC:TermGenie") "apoptosis involved in development of an anatomical structure") +AnnotationAssertion(Annotation( "GOC:TermGenie") "apoptosis signaling involved in anatomical structure development") +AnnotationAssertion(Annotation( "GOC:TermGenie") "apoptosis signaling involved in development of an anatomical structure") +AnnotationAssertion(Annotation( "GOC:TermGenie") "apoptotic program involved in anatomical structure development") +AnnotationAssertion(Annotation( "GOC:TermGenie") "apoptotic program involved in development of an anatomical structure") +AnnotationAssertion(Annotation( "GOC:TermGenie") "type I programmed cell death involved in anatomical structure development") +AnnotationAssertion(Annotation( "GOC:TermGenie") "type I programmed cell death involved in development of an anatomical structure") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "apoptosis activator activity involved in anatomical structure development") +AnnotationAssertion(Annotation( "GOC:TermGenie") "apoptosis activator activity involved in development of an anatomical structure") +AnnotationAssertion(Annotation( "GOC:TermGenie") "commitment to apoptosis involved in anatomical structure development") +AnnotationAssertion(Annotation( "GOC:TermGenie") "commitment to apoptosis involved in development of an anatomical structure") +AnnotationAssertion(Annotation( "GOC:TermGenie") "induction of apoptosis by p53 involved in anatomical structure development") +AnnotationAssertion(Annotation( "GOC:TermGenie") "induction of apoptosis by p53 involved in development of an anatomical structure") +AnnotationAssertion(Annotation( "GOC:TermGenie") "induction of apoptosis involved in anatomical structure development") +AnnotationAssertion(Annotation( "GOC:TermGenie") "induction of apoptosis involved in development of an anatomical structure") +AnnotationAssertion(Annotation( "GOC:TermGenie") "signaling (initiator) caspase activity involved in anatomical structure development") +AnnotationAssertion(Annotation( "GOC:TermGenie") "signaling (initiator) caspase activity involved in development of an anatomical structure") +AnnotationAssertion( "GO:1902742") +AnnotationAssertion(rdfs:label "apoptotic process involved in development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of lens fiber cell differentiation) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mr") Annotation( "GO_REF:0000058") Annotation( "PMID:17592637") "Any process that modulates the frequency, rate or extent of lens fiber cell differentiation.") +AnnotationAssertion( "mr") +AnnotationAssertion( "2014-03-03T23:18:50Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of lens fibre cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902746") +AnnotationAssertion(rdfs:label "regulation of lens fiber cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of lens fiber cell differentiation) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mr") Annotation( "GO_REF:0000058") Annotation( "PMID:17592637") "Any process that stops, prevents or reduces the frequency, rate or extent of lens fiber cell differentiation.") +AnnotationAssertion( "mr") +AnnotationAssertion( "2014-03-03T23:19:32Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of lens fiber cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of lens fibre cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of lens fiber cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of lens fibre cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of lens fiber cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of lens fibre cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of lens fibre cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of lens fiber cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of lens fibre cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902747") +AnnotationAssertion(rdfs:label "negative regulation of lens fiber cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (positive regulation of lens fiber cell differentiation) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mr") Annotation( "GO_REF:0000058") Annotation( "PMID:17592637") "Any process that activates or increases the frequency, rate or extent of lens fiber cell differentiation.") +AnnotationAssertion( "mr") +AnnotationAssertion( "2014-03-03T23:20:12Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of lens fibre cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of lens fiber cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of lens fibre cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of lens fiber cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of lens fibre cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of lens fiber cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of lens fibre cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of lens fiber cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of lens fibre cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902748") +AnnotationAssertion(rdfs:label "positive regulation of lens fiber cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (positive regulation of chondrocyte development) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mr") Annotation( "GO_REF:0000058") Annotation( "PMID:16575901") "Any process that activates or increases the frequency, rate or extent of chondrocyte development.") +AnnotationAssertion( "mr") +AnnotationAssertion( "2014-03-07T17:45:55Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of chondrocyte development") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of chondrocyte development") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of chondrocyte development") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of chondrocyte development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902761") +AnnotationAssertion(rdfs:label "positive regulation of chondrocyte development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (response to alkane) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mengo_curators") Annotation( "GO_REF:0000071") Annotation( "PMID:22958739") Annotation( "PMID:23826995") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkane stimulus.") +AnnotationAssertion( "GO:1990373") +AnnotationAssertion( "process resulting in tolerance to alkane") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902778") +AnnotationAssertion(rdfs:label "response to alkane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (cellular response to alkane) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mengo_curators") Annotation( "GO_REF:0000071") Annotation( "PMID:22958739") Annotation( "PMID:23826995") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkane stimulus.") +AnnotationAssertion( "tt") +AnnotationAssertion( "2014-03-21T03:18:04Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902779") +AnnotationAssertion(rdfs:label "cellular response to alkane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of skeletal muscle fiber differentiation) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mr") Annotation( "GO_REF:0000058") Annotation( "PMID:17879321") "Any process that modulates the frequency, rate or extent of skeletal muscle fiber differentiation.") +AnnotationAssertion( "mr") +AnnotationAssertion( "2014-03-26T21:18:26Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902809") +AnnotationAssertion(rdfs:label "regulation of skeletal muscle fiber differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of skeletal muscle fiber differentiation) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mr") Annotation( "GO_REF:0000058") Annotation( "PMID:17879321") "Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle fiber differentiation.") +AnnotationAssertion( "mr") +AnnotationAssertion( "2014-03-26T21:18:32Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of skeletal muscle fiber differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of skeletal muscle fiber differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of skeletal muscle fiber differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of skeletal muscle fiber differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902810") +AnnotationAssertion(rdfs:label "negative regulation of skeletal muscle fiber differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of skeletal muscle fiber differentiation) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mr") Annotation( "GO_REF:0000058") Annotation( "PMID:17879321") "Any process that activates or increases the frequency, rate or extent of skeletal muscle fiber differentiation.") +AnnotationAssertion( "mr") +AnnotationAssertion( "2014-03-26T21:18:38Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of skeletal muscle fiber differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of skeletal muscle fiber differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of skeletal muscle fiber differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of skeletal muscle fiber differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902811") +AnnotationAssertion(rdfs:label "positive regulation of skeletal muscle fiber differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of protein localization to microtubule) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:vw") Annotation( "GO_REF:0000058") Annotation( "PMID:23087209") "Any process that modulates the frequency, rate or extent of protein localization to microtubule.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2014-03-27T22:07:12Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of protein localisation to microtubule") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902816") +AnnotationAssertion(rdfs:label "regulation of protein localization to microtubule") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of protein localization to microtubule) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:vw") Annotation( "GO_REF:0000058") Annotation( "PMID:23087209") "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to microtubule.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2014-03-27T22:07:18Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of protein localisation to microtubule") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of protein localization to microtubule") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of protein localisation to microtubule") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of protein localization to microtubule") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of protein localisation to microtubule") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of protein localization to microtubule") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of protein localisation to microtubule") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of protein localisation to microtubule") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of protein localization to microtubule") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902817") +AnnotationAssertion(rdfs:label "negative regulation of protein localization to microtubule") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of cell proliferation in dorsal spinal cord) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mr") Annotation( "GO_REF:0000058") Annotation( "PMID:21730158") "Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation in dorsal spinal cord.") +AnnotationAssertion( "mr") +AnnotationAssertion( "2014-03-31T17:42:50Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of cell proliferation in dorsal spinal cord") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of cell proliferation in dorsal spinal cord") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of cell proliferation in dorsal spinal cord") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of cell proliferation in dorsal spinal cord") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902832") +AnnotationAssertion(rdfs:label "negative regulation of cell proliferation in dorsal spinal cord") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of cell proliferation in dorsal spinal cord) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mr") Annotation( "GO_REF:0000058") Annotation( "PMID:21730158") "Any process that activates or increases the frequency, rate or extent of cell proliferation in dorsal spinal cord.") +AnnotationAssertion( "mr") +AnnotationAssertion( "2014-03-31T17:43:33Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of cell proliferation in dorsal spinal cord") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of cell proliferation in dorsal spinal cord") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of cell proliferation in dorsal spinal cord") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of cell proliferation in dorsal spinal cord") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902833") +AnnotationAssertion(rdfs:label "positive regulation of cell proliferation in dorsal spinal cord") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of nuclear migration along microtubule) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:23087209") "Any process that modulates the frequency, rate or extent of nuclear migration along microtubule.") +AnnotationAssertion( "vw") +AnnotationAssertion( "2014-04-01T13:50:23Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of nuclear movement, microtubule-mediated") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of nucleus migration") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of microtubule cytoskeleton-dependent nuclear positioning") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of microtubule cytoskeleton-dependent nucleus positioning") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of microtubule-dependent nuclear positioning") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of microtubule-dependent nucleus positioning") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of microtubule-mediated nuclear migration") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of nuclear migration, microtubule-mediated") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of transport of nucleus by microtubules") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of transport of nucleus, microtubule-mediated") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902838") +AnnotationAssertion(rdfs:label "regulation of nuclear migration along microtubule") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of nuclear migration along microtubule) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:23087209") "Any process that stops, prevents or reduces the frequency, rate or extent of nuclear migration along microtubule.") +AnnotationAssertion( "vw") +AnnotationAssertion( "2014-04-01T13:50:29Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of microtubule cytoskeleton-dependent nuclear positioning") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of microtubule cytoskeleton-dependent nucleus positioning") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of microtubule-dependent nuclear positioning") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of microtubule-dependent nucleus positioning") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of microtubule-mediated nuclear migration") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of nuclear migration along microtubule") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of nuclear migration, microtubule-mediated") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of transport of nucleus by microtubules") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of transport of nucleus, microtubule-mediated") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of microtubule cytoskeleton-dependent nuclear positioning") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of microtubule cytoskeleton-dependent nucleus positioning") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of microtubule-dependent nuclear positioning") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of microtubule-dependent nucleus positioning") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of microtubule-mediated nuclear migration") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of nuclear migration along microtubule") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of nuclear migration, microtubule-mediated") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of transport of nucleus by microtubules") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of transport of nucleus, microtubule-mediated") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of microtubule cytoskeleton-dependent nuclear positioning") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of microtubule cytoskeleton-dependent nucleus positioning") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of microtubule-dependent nuclear positioning") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of microtubule-dependent nucleus positioning") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of microtubule-mediated nuclear migration") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of nuclear migration along microtubule") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of nuclear migration, microtubule-mediated") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of transport of nucleus by microtubules") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of transport of nucleus, microtubule-mediated") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of microtubule cytoskeleton-dependent nuclear positioning") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of microtubule cytoskeleton-dependent nucleus positioning") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of microtubule-dependent nuclear positioning") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of microtubule-dependent nucleus positioning") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of microtubule-mediated nuclear migration") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of nuclear migration, microtubule-mediated") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of transport of nucleus by microtubules") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of transport of nucleus, microtubule-mediated") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of microtubule cytoskeleton-dependent nuclear positioning") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of microtubule cytoskeleton-dependent nucleus positioning") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of microtubule-dependent nuclear positioning") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of microtubule-dependent nucleus positioning") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of microtubule-mediated nuclear migration") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of nuclear migration along microtubule") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of nuclear migration, microtubule-mediated") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of transport of nucleus by microtubules") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of transport of nucleus, microtubule-mediated") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902839") +AnnotationAssertion(rdfs:label "negative regulation of nuclear migration along microtubule") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of nuclear migration along microtubule) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:23087209") "Any process that activates or increases the frequency, rate or extent of nuclear migration along microtubule.") +AnnotationAssertion( "vw") +AnnotationAssertion( "2014-04-01T13:50:35Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of microtubule cytoskeleton-dependent nuclear positioning") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of microtubule cytoskeleton-dependent nucleus positioning") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of microtubule-dependent nuclear positioning") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of microtubule-dependent nucleus positioning") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of microtubule-mediated nuclear migration") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of nuclear migration, microtubule-mediated") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of transport of nucleus by microtubules") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of transport of nucleus, microtubule-mediated") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of microtubule cytoskeleton-dependent nuclear positioning") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of microtubule cytoskeleton-dependent nucleus positioning") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of microtubule-dependent nuclear positioning") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of microtubule-dependent nucleus positioning") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of microtubule-mediated nuclear migration") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of nuclear migration along microtubule") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of nuclear migration, microtubule-mediated") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of transport of nucleus by microtubules") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of transport of nucleus, microtubule-mediated") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of microtubule cytoskeleton-dependent nuclear positioning") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of microtubule cytoskeleton-dependent nucleus positioning") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of microtubule-dependent nuclear positioning") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of microtubule-dependent nucleus positioning") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of microtubule-mediated nuclear migration") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of nuclear migration along microtubule") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of nuclear migration, microtubule-mediated") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of transport of nucleus by microtubules") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of transport of nucleus, microtubule-mediated") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of microtubule cytoskeleton-dependent nuclear positioning") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of microtubule cytoskeleton-dependent nucleus positioning") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of microtubule-dependent nuclear positioning") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of microtubule-dependent nucleus positioning") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of microtubule-mediated nuclear migration") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of nuclear migration along microtubule") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of nuclear migration, microtubule-mediated") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of transport of nucleus by microtubules") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of transport of nucleus, microtubule-mediated") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of microtubule cytoskeleton-dependent nuclear positioning") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of microtubule cytoskeleton-dependent nucleus positioning") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of microtubule-dependent nuclear positioning") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of microtubule-dependent nucleus positioning") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of microtubule-mediated nuclear migration") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of nuclear migration along microtubule") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of nuclear migration, microtubule-mediated") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of transport of nucleus by microtubules") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of transport of nucleus, microtubule-mediated") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902840") +AnnotationAssertion(rdfs:label "positive regulation of nuclear migration along microtubule") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (microtubule cytoskeleton organization involved in mitosis) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000060") Annotation( "PMID:18799626") "Any microtubule cytoskeleton organization that is involved in mitosis.") +AnnotationAssertion( "vw") +AnnotationAssertion( "2014-04-02T14:19:38Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "microtubule cytoskeleton organisation involved in mitosis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "microtubule dynamics involved in mitosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "microtubule cytoskeleton organization and biogenesis involved in mitosis") +AnnotationAssertion( "GO:1902850") +AnnotationAssertion(rdfs:label "microtubule cytoskeleton organization involved in mitosis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of non-motile cilium assembly) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:cilia") Annotation( "GOC:kmv") Annotation( "GO_REF:0000058") Annotation( "PMID:23807208") "Any process that modulates the frequency, rate or extent of non-motile cilium assembly.") +AnnotationAssertion( "kmv") +AnnotationAssertion( "2014-04-02T15:41:57Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of immotile primary cilium assembly") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of nonmotile primary cilia assembly") +AnnotationAssertion( "regulation of nonmotile primary cilium assembly") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of sensory cilium assembly") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of sensory cilium biogenesis") +AnnotationAssertion( "GO:1902855") +AnnotationAssertion(rdfs:label "regulation of non-motile cilium assembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of non-motile cilium assembly) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:cilia") Annotation( "GOC:kmv") Annotation( "GO_REF:0000058") Annotation( "PMID:23807208") "Any process that stops, prevents or reduces the frequency, rate or extent of non-motile cilium assembly.") +AnnotationAssertion( "kmv") +AnnotationAssertion( "2014-04-02T15:42:17Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of immotile primary cilium assembly") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of nonmotile primary cilium assembly") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of sensory cilium assembly") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of immotile primary cilium assembly") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of nonmotile primary cilia assembly") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of nonmotile primary cilium assembly") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of sensory cilium assembly") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of sensory cilium biogenesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of immotile primary cilium assembly") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of nonmotile primary cilia assembly") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of nonmotile primary cilium assembly") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of sensory cilium assembly") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of sensory cilium biogenesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of immotile primary cilium assembly") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of nonmotile primary cilia assembly") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of nonmotile primary cilium assembly") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of sensory cilium assembly") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of sensory cilium biogenesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of nonmotile primary cilia assembly") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of sensory cilium biogenesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of immotile primary cilium assembly") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of nonmotile primary cilia assembly") +AnnotationAssertion( "negative regulation of nonmotile primary cilium assembly") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of sensory cilium assembly") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of sensory cilium biogenesis") +AnnotationAssertion( "GO:1902856") +AnnotationAssertion(rdfs:label "negative regulation of non-motile cilium assembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of non-motile cilium assembly) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:cilia") Annotation( "GOC:kmv") Annotation( "GO_REF:0000058") Annotation( "PMID:23807208") "Any process that activates or increases the frequency, rate or extent of non-motile cilium assembly.") +AnnotationAssertion( "kmv") +AnnotationAssertion( "2014-04-02T15:42:31Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of immotile primary cilium assembly") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of nonmotile primary cilium assembly") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of sensory cilium assembly") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of nonmotile primary cilia assembly") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of sensory cilium biogenesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of immotile primary cilium assembly") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of nonmotile primary cilia assembly") +AnnotationAssertion( "positive regulation of nonmotile primary cilium assembly") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of sensory cilium assembly") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of sensory cilium biogenesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of immotile primary cilium assembly") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of nonmotile primary cilia assembly") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of nonmotile primary cilium assembly") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of sensory cilium assembly") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of sensory cilium biogenesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of immotile primary cilium assembly") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of nonmotile primary cilia assembly") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of nonmotile primary cilium assembly") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of sensory cilium assembly") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of sensory cilium biogenesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of immotile primary cilium assembly") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of nonmotile primary cilia assembly") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of nonmotile primary cilium assembly") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of sensory cilium assembly") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of sensory cilium biogenesis") +AnnotationAssertion( "GO:1902857") +AnnotationAssertion(rdfs:label "positive regulation of non-motile cilium assembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of embryonic camera-type eye development) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mr") Annotation( "GO_REF:0000058") Annotation( "PMID:16872597") "Any process that modulates the frequency, rate or extent of embryonic camera-type eye development.") +AnnotationAssertion( "mr") +AnnotationAssertion( "2014-04-03T15:24:00Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of embryonic eye development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902863") +AnnotationAssertion(rdfs:label "regulation of embryonic camera-type eye development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of embryonic camera-type eye development) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mr") Annotation( "GO_REF:0000058") Annotation( "PMID:16872597") "Any process that stops, prevents or reduces the frequency, rate or extent of embryonic camera-type eye development.") +AnnotationAssertion( "mr") +AnnotationAssertion( "2014-04-03T15:24:06Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of embryonic camera-type eye development") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of embryonic eye development") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of embryonic camera-type eye development") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of embryonic eye development") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of embryonic camera-type eye development") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of embryonic eye development") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of embryonic eye development") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of embryonic camera-type eye development") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of embryonic eye development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902864") +AnnotationAssertion(rdfs:label "negative regulation of embryonic camera-type eye development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of embryonic camera-type eye development) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mr") Annotation( "GO_REF:0000058") Annotation( "PMID:16872597") "Any process that activates or increases the frequency, rate or extent of embryonic camera-type eye development.") +AnnotationAssertion( "mr") +AnnotationAssertion( "2014-04-03T15:24:12Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of embryonic eye development") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of embryonic camera-type eye development") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of embryonic eye development") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of embryonic camera-type eye development") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of embryonic eye development") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of embryonic camera-type eye development") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of embryonic eye development") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of embryonic camera-type eye development") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of embryonic eye development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902865") +AnnotationAssertion(rdfs:label "positive regulation of embryonic camera-type eye development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of retina development in camera-type eye) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mr") Annotation( "GO_REF:0000058") Annotation( "PMID:16872597") "Any process that modulates the frequency, rate or extent of retina development in camera-type eye.") +AnnotationAssertion( "mr") +AnnotationAssertion( "2014-04-03T15:24:17Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of retina development in camera-style eye") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of retinal development") +AnnotationAssertion( "GO:1902866") +AnnotationAssertion(rdfs:label "regulation of retina development in camera-type eye") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of retina development in camera-type eye) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mr") Annotation( "GO_REF:0000058") Annotation( "PMID:16872597") "Any process that stops, prevents or reduces the frequency, rate or extent of retina development in camera-type eye.") +AnnotationAssertion( "mr") +AnnotationAssertion( "2014-04-03T15:24:23Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of retina development in camera-style eye") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of retina development in camera-type eye") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of retina development in camera-style eye") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of retina development in camera-type eye") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of retina development in camera-style eye") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of retina development in camera-type eye") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of retina development in camera-style eye") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of retina development in camera-style eye") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of retina development in camera-type eye") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of retinal development") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of retinal development") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of retinal development") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of retinal development") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of retinal development") +AnnotationAssertion( "GO:1902867") +AnnotationAssertion(rdfs:label "negative regulation of retina development in camera-type eye") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (positive regulation of retina development in camera-type eye) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mr") Annotation( "GO_REF:0000058") Annotation( "PMID:16872597") "Any process that activates or increases the frequency, rate or extent of retina development in camera-type eye.") +AnnotationAssertion( "mr") +AnnotationAssertion( "2014-04-03T15:24:29Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of retina development in camera-style eye") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of retina development in camera-style eye") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of retina development in camera-type eye") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of retina development in camera-style eye") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of retina development in camera-type eye") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of retina development in camera-style eye") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of retina development in camera-type eye") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of retina development in camera-style eye") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of retina development in camera-type eye") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of retinal development") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of retinal development") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of retinal development") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of retinal development") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of retinal development") +AnnotationAssertion( "GO:1902868") +AnnotationAssertion(rdfs:label "positive regulation of retina development in camera-type eye") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (regulation of amacrine cell differentiation) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mr") Annotation( "GO_REF:0000058") Annotation( "PMID:16872597") "Any process that modulates the frequency, rate or extent of amacrine cell differentiation.") +AnnotationAssertion( "mr") +AnnotationAssertion( "2014-04-03T15:24:35Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of amacrine neuron differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902869") +AnnotationAssertion(rdfs:label "regulation of amacrine cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of amacrine cell differentiation) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mr") Annotation( "GO_REF:0000058") Annotation( "PMID:16872597") "Any process that stops, prevents or reduces the frequency, rate or extent of amacrine cell differentiation.") +AnnotationAssertion( "mr") +AnnotationAssertion( "2014-04-03T15:24:40Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of amacrine cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of amacrine neuron differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of amacrine cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of amacrine neuron differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of amacrine cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of amacrine neuron differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of amacrine neuron differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of amacrine cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of amacrine neuron differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902870") +AnnotationAssertion(rdfs:label "negative regulation of amacrine cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of amacrine cell differentiation) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mr") Annotation( "GO_REF:0000058") Annotation( "PMID:16872597") "Any process that activates or increases the frequency, rate or extent of amacrine cell differentiation.") +AnnotationAssertion( "mr") +AnnotationAssertion( "2014-04-03T15:24:46Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of amacrine neuron differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of amacrine cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of amacrine neuron differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of amacrine cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of amacrine neuron differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of amacrine cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of amacrine neuron differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of amacrine cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of amacrine neuron differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902871") +AnnotationAssertion(rdfs:label "positive regulation of amacrine cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of embryonic pattern specification) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mr") Annotation( "GO_REF:0000058") Annotation( "PMID:16872597") "Any process that modulates the frequency, rate or extent of embryonic pattern specification.") +AnnotationAssertion( "mr") +AnnotationAssertion( "2014-04-03T15:25:15Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of embryonic pattern biosynthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of embryonic pattern formation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of ventral/lateral system") +AnnotationAssertion( "GO:1902875") +AnnotationAssertion(rdfs:label "regulation of embryonic pattern specification") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of embryonic pattern specification) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mr") Annotation( "GO_REF:0000058") Annotation( "PMID:16872597") "Any process that stops, prevents or reduces the frequency, rate or extent of embryonic pattern specification.") +AnnotationAssertion( "mr") +AnnotationAssertion( "2014-04-03T15:25:20Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of embryonic pattern specification") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of embryonic pattern specification") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of embryonic pattern specification") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of embryonic pattern specification") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of ventral/lateral system") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of ventral/lateral system") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of ventral/lateral system") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of ventral/lateral system") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of ventral/lateral system") +AnnotationAssertion( "GO:1902876") +AnnotationAssertion(rdfs:label "negative regulation of embryonic pattern specification") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of embryonic pattern specification) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mr") Annotation( "GO_REF:0000058") Annotation( "PMID:16872597") "Any process that activates or increases the frequency, rate or extent of embryonic pattern specification.") +AnnotationAssertion( "mr") +AnnotationAssertion( "2014-04-03T15:25:26Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of embryonic pattern specification") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of embryonic pattern specification") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of embryonic pattern specification") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of embryonic pattern specification") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of ventral/lateral system") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of ventral/lateral system") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of ventral/lateral system") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of ventral/lateral system") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of ventral/lateral system") +AnnotationAssertion( "GO:1902877") +AnnotationAssertion(rdfs:label "positive regulation of embryonic pattern specification") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of supramolecular fiber organization) + +AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "GO_REF:0000058") Annotation( "PMID:23921388") "Any process that modulates the frequency, rate or extent of supramolecular fiber organization.") +AnnotationAssertion( "rl") +AnnotationAssertion( "2014-04-15T16:46:36Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of fibril organisation") +AnnotationAssertion( "GO:1902903") +AnnotationAssertion(rdfs:comment "HSPA8, human, P11142 in PMID:23921388 inferred from direct assay to negatively regulate fibrillation of alpha-Syn in vitro") +AnnotationAssertion(rdfs:label "regulation of supramolecular fiber organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of supramolecular fiber organization) + +AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "GO_REF:0000058") Annotation( "PMID:23921388") "Any process that stops, prevents or reduces the frequency, rate or extent of fibril organization.") +AnnotationAssertion( "rl") +AnnotationAssertion( "2014-04-15T16:46:42Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of fibril organisation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of fibril organization") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of fibril organisation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of fibril organization") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of fibril organisation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of fibril organization") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of fibril organisation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of fibril organization") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of fibril organisation") +AnnotationAssertion( "GO:1902904") +AnnotationAssertion(rdfs:comment "HSPA8, human, P11142 in PMID:23921388 inferred from direct assay to negatively regulate fibrillation of alpha-Syn in vitro") +AnnotationAssertion(rdfs:label "negative regulation of supramolecular fiber organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of supramolecular fiber organization) + +AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "GO_REF:0000058") Annotation( "PMID:23921388") "Any process that activates or increases the frequency, rate or extent of supramolecular fiber organization.") +AnnotationAssertion( "rl") +AnnotationAssertion( "2014-04-15T16:46:48Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of fibril organisation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of fibril organization") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of fibril organisation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of fibril organisation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of fibril organization") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of fibril organisation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of fibril organization") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of fibril organisation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of fibril organization") +AnnotationAssertion( "GO:1902905") +AnnotationAssertion(rdfs:comment "HSPA8, human, P11142 in PMID:23921388 inferred from direct assay to negatively regulate fibrillation of alpha-Syn in vitro") +AnnotationAssertion(rdfs:label "positive regulation of supramolecular fiber organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of melanosome transport) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:als") Annotation( "GO_REF:0000058") Annotation( "PMID:23334344") "Any process that modulates the frequency, rate or extent of melanosome transport.") +AnnotationAssertion( "als") +AnnotationAssertion( "2014-04-17T11:40:16Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902908") +AnnotationAssertion(rdfs:label "regulation of melanosome transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (negative regulation of melanosome transport) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:als") Annotation( "GO_REF:0000058") Annotation( "PMID:23334344") "Any process that stops, prevents or reduces the frequency, rate or extent of melanosome transport.") +AnnotationAssertion( "als") +AnnotationAssertion( "2014-04-17T11:40:28Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of melanosome transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of melanosome transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of melanosome transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of melanosome transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902909") +AnnotationAssertion(rdfs:label "negative regulation of melanosome transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (positive regulation of melanosome transport) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:als") Annotation( "GO_REF:0000058") Annotation( "PMID:23334344") "Any process that activates or increases the frequency, rate or extent of melanosome transport.") +AnnotationAssertion( "als") +AnnotationAssertion( "2014-04-17T11:40:34Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of melanosome transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of melanosome transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of melanosome transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of melanosome transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902910") +AnnotationAssertion(rdfs:label "positive regulation of melanosome transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (protein kinase complex) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:bhm") Annotation( "GO_REF:0000088") Annotation( "PMID:24606918") "A protein complex which is capable of protein kinase activity.") +AnnotationAssertion( "bhm") +AnnotationAssertion( "2014-04-17T13:52:40Z") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:1902911") +AnnotationAssertion(rdfs:comment "An example of this is PKM2 in human (P14618) in PMID:24606918 (inferred from direct assay).") +AnnotationAssertion(rdfs:label "protein kinase complex") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of neuroepithelial cell differentiation) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mr") Annotation( "GO_REF:0000058") Annotation( "PMID:16916506") "Any process that activates or increases the frequency, rate or extent of neuroepithelial cell differentiation.") +AnnotationAssertion( "mr") +AnnotationAssertion( "2014-04-18T21:06:42Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of neuroepithelial cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of neuroepithelial cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of neuroepithelial cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of neuroepithelial cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902913") +AnnotationAssertion(rdfs:label "positive regulation of neuroepithelial cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of alcohol biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mengo_curators") Annotation( "GO_REF:0000058") Annotation( "PMID:23332010") "Any process that modulates the frequency, rate or extent of alcohol biosynthetic process.") +AnnotationAssertion( "tt") +AnnotationAssertion( "2014-04-22T21:55:03Z") +AnnotationAssertion( "regulation of solventogenesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of alcohol anabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of alcohol biosynthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of alcohol formation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of alcohol synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902930") +AnnotationAssertion(rdfs:label "regulation of alcohol biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of alcohol biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mengo_curators") Annotation( "GO_REF:0000058") Annotation( "PMID:23332010") "Any process that stops, prevents or reduces the frequency, rate or extent of alcohol biosynthetic process.") +AnnotationAssertion( "tt") +AnnotationAssertion( "2014-04-22T21:55:13Z") +AnnotationAssertion( "negative regulation of solventogenesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of alcohol anabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of alcohol biosynthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of alcohol biosynthetic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of alcohol formation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of alcohol synthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of alcohol anabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of alcohol biosynthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of alcohol biosynthetic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of alcohol formation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of alcohol synthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of alcohol anabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of alcohol biosynthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of alcohol biosynthetic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of alcohol formation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of alcohol synthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of alcohol anabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of alcohol biosynthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of alcohol formation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of alcohol synthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of alcohol anabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of alcohol biosynthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of alcohol biosynthetic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of alcohol formation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of alcohol synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902931") +AnnotationAssertion(rdfs:label "negative regulation of alcohol biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of alcohol biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mengo_curators") Annotation( "GO_REF:0000058") Annotation( "PMID:23332010") "Any process that activates or increases the frequency, rate or extent of alcohol biosynthetic process.") +AnnotationAssertion( "tt") +AnnotationAssertion( "2014-04-22T21:55:19Z") +AnnotationAssertion( "positive regulation of solventogenesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of alcohol anabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of alcohol biosynthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of alcohol formation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of alcohol synthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of alcohol anabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of alcohol biosynthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of alcohol biosynthetic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of alcohol formation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of alcohol synthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of alcohol anabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of alcohol biosynthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of alcohol biosynthetic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of alcohol formation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of alcohol synthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of alcohol anabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of alcohol biosynthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of alcohol biosynthetic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of alcohol formation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of alcohol synthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of alcohol anabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of alcohol biosynthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of alcohol biosynthetic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of alcohol formation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of alcohol synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1902932") +AnnotationAssertion(rdfs:label "positive regulation of alcohol biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of lipid transport across blood-brain barrier) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:sjp") Annotation( "GO_REF:0000058") Annotation( "PMID:24345162") "Any process that modulates the frequency, rate or extent of lipid transport across blood-brain barrier.") +AnnotationAssertion( "sjp") +AnnotationAssertion( "2014-05-09T09:30:04Z") +AnnotationAssertion( "regulation of lipid transport across blood brain barrier") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1903000") +AnnotationAssertion(rdfs:label "regulation of lipid transport across blood-brain barrier") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectAllValuesFrom( )) + +# Class: (negative regulation of lipid transport across blood-brain barrier) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:sjp") Annotation( "GO_REF:0000058") Annotation( "PMID:24345162") "Any process that stops, prevents or reduces the frequency, rate or extent of lipid transport across blood-brain barrier.") +AnnotationAssertion( "sjp") +AnnotationAssertion( "2014-05-09T09:30:10Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of lipid transport across blood brain barrier") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of lipid transport across blood brain barrier") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of lipid transport across blood brain barrier") +AnnotationAssertion( "negative regulation of lipid transport across blood brain barrier") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of lipid transport across blood brain barrier") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1903001") +AnnotationAssertion(rdfs:label "negative regulation of lipid transport across blood-brain barrier") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of lipid transport across blood-brain barrier) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:sjp") Annotation( "GO_REF:0000058") Annotation( "PMID:24345162") "Any process that activates or increases the frequency, rate or extent of lipid transport across blood-brain barrier.") +AnnotationAssertion( "sjp") +AnnotationAssertion( "2014-05-09T09:30:16Z") +AnnotationAssertion( "positive regulation of lipid transport across blood brain barrier") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of lipid transport across blood brain barrier") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of lipid transport across blood brain barrier") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of lipid transport across blood brain barrier") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of lipid transport across blood brain barrier") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1903002") +AnnotationAssertion(rdfs:label "positive regulation of lipid transport across blood-brain barrier") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (organelle disassembly) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000079") "The disaggregation of an organelle into its constituent components.") +AnnotationAssertion( "jl") +AnnotationAssertion( "2014-05-13T12:36:03Z") +AnnotationAssertion( "organelle degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1903008") +AnnotationAssertion(rdfs:label "organelle disassembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of bone development) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mr") Annotation( "GO_REF:0000058") Annotation( "PMID:22510437") "Any process that modulates the frequency, rate or extent of bone development.") +AnnotationAssertion( "mr") +AnnotationAssertion( "2014-05-13T22:41:53Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1903010") +AnnotationAssertion(rdfs:label "regulation of bone development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (negative regulation of bone development) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mr") Annotation( "GO_REF:0000058") Annotation( "PMID:22510437") "Any process that stops, prevents or reduces the frequency, rate or extent of bone development.") +AnnotationAssertion( "mr") +AnnotationAssertion( "2014-05-13T22:42:00Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of bone development") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of bone development") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of bone development") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of bone development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1903011") +AnnotationAssertion(rdfs:label "negative regulation of bone development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of bone development) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mr") Annotation( "GO_REF:0000058") Annotation( "PMID:22510437") "Any process that activates or increases the frequency, rate or extent of bone development.") +AnnotationAssertion( "mr") +AnnotationAssertion( "2014-05-13T22:42:06Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of bone development") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of bone development") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of bone development") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of bone development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1903012") +AnnotationAssertion(rdfs:label "positive regulation of bone development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of glycoprotein metabolic process) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "GO_REF:0000058") Annotation( "PMID:23544079") "Any process that modulates the frequency, rate or extent of glycoprotein metabolic process.") +AnnotationAssertion( "rl") +AnnotationAssertion( "2014-05-14T18:44:19Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of glycoprotein metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1903018") +AnnotationAssertion(rdfs:comment "human serum amyloid P component (SAP) P02743 inhibits viral neuraminidase, NA (exo-alpha-sialidase activity) and thus the metabolism of glycoproteins, demonstrated in Figure 4A PMID:23544079, (IDA), the negative regulation term would be applied to this protein") +AnnotationAssertion(rdfs:label "regulation of glycoprotein metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of glycoprotein metabolic process) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "GO_REF:0000058") Annotation( "PMID:23544079") "Any process that stops, prevents or reduces the frequency, rate or extent of glycoprotein metabolic process.") +AnnotationAssertion( "rl") +AnnotationAssertion( "2014-05-14T18:44:25Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of glycoprotein metabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of glycoprotein metabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of glycoprotein metabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of glycoprotein metabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of glycoprotein metabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of glycoprotein metabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of glycoprotein metabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of glycoprotein metabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of glycoprotein metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1903019") +AnnotationAssertion(rdfs:comment "human serum amyloid P component (SAP) P02743 inhibits viral neuraminidase, NA (exo-alpha-sialidase activity) and thus the metabolism of glycoproteins, demonstrated in Figure 4A PMID:23544079, (IDA), the negative regulation term would be applied to this protein") +AnnotationAssertion(rdfs:label "negative regulation of glycoprotein metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of glycoprotein metabolic process) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "GO_REF:0000058") Annotation( "PMID:23544079") "Any process that activates or increases the frequency, rate or extent of glycoprotein metabolic process.") +AnnotationAssertion( "rl") +AnnotationAssertion( "2014-05-14T18:44:31Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of glycoprotein metabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of glycoprotein metabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of glycoprotein metabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of glycoprotein metabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of glycoprotein metabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of glycoprotein metabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of glycoprotein metabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of glycoprotein metabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of glycoprotein metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1903020") +AnnotationAssertion(rdfs:comment "human serum amyloid P component (SAP) P02743 inhibits viral neuraminidase, NA (exo-alpha-sialidase activity) and thus the metabolism of glycoproteins, demonstrated in Figure 4A PMID:23544079, (IDA), the negative regulation term would be applied to this protein") +AnnotationAssertion(rdfs:label "positive regulation of glycoprotein metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of response to wounding) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:kmv") Annotation( "GO_REF:0000058") Annotation( "PMID:19164535") "Any process that modulates the frequency, rate or extent of response to wounding.") +AnnotationAssertion( "kmv") +AnnotationAssertion( "2014-05-18T01:28:46Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of physiological response to wounding") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1903034") +AnnotationAssertion(rdfs:label "regulation of response to wounding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (negative regulation of response to wounding) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:kmv") Annotation( "GO_REF:0000058") Annotation( "PMID:19164535") "Any process that stops, prevents or reduces the frequency, rate or extent of response to wounding.") +AnnotationAssertion( "kmv") +AnnotationAssertion( "2014-05-18T01:28:52Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of physiological response to wounding") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of response to wounding") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of physiological response to wounding") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of response to wounding") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of physiological response to wounding") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of response to wounding") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of physiological response to wounding") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of physiological response to wounding") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of response to wounding") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1903035") +AnnotationAssertion(rdfs:label "negative regulation of response to wounding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of response to wounding) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:kmv") Annotation( "GO_REF:0000058") Annotation( "PMID:19164535") "Any process that activates or increases the frequency, rate or extent of response to wounding.") +AnnotationAssertion( "kmv") +AnnotationAssertion( "2014-05-18T01:28:58Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of physiological response to wounding") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of physiological response to wounding") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of response to wounding") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of physiological response to wounding") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of response to wounding") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of physiological response to wounding") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of response to wounding") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of physiological response to wounding") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of response to wounding") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1903036") +AnnotationAssertion(rdfs:label "positive regulation of response to wounding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of leukocyte cell-cell adhesion) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "GO_REF:0000058") Annotation( "PMID:21106532") "Any process that modulates the frequency, rate or extent of leukocyte cell-cell adhesion.") +AnnotationAssertion( "rl") +AnnotationAssertion( "2014-05-19T15:29:58Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of leukocyte adhesion") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of leukocyte cell adhesion") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1903037") +AnnotationAssertion(rdfs:comment "Exogenous expression of ASS1 or NOS3 in HUVECs enhances NO production and inhibits monocyte adhesion") +AnnotationAssertion(rdfs:label "regulation of leukocyte cell-cell adhesion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (negative regulation of leukocyte cell-cell adhesion) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "GO_REF:0000058") Annotation( "PMID:21106532") "Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte cell-cell adhesion.") +AnnotationAssertion( "rl") +AnnotationAssertion( "2014-05-19T15:30:05Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of leukocyte adhesion") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of leukocyte cell adhesion") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of leukocyte cell-cell adhesion") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of leukocyte adhesion") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of leukocyte cell adhesion") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of leukocyte cell-cell adhesion") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of leukocyte adhesion") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of leukocyte cell adhesion") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of leukocyte cell-cell adhesion") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of leukocyte adhesion") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of leukocyte cell adhesion") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of leukocyte adhesion") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of leukocyte cell adhesion") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of leukocyte cell-cell adhesion") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1903038") +AnnotationAssertion(rdfs:comment "Exogenous expression of ASS1 or NOS3 in HUVECs enhances NO production and inhibits monocyte adhesion") +AnnotationAssertion(rdfs:label "negative regulation of leukocyte cell-cell adhesion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of leukocyte cell-cell adhesion) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "GO_REF:0000058") Annotation( "PMID:21106532") "Any process that activates or increases the frequency, rate or extent of leukocyte cell-cell adhesion.") +AnnotationAssertion( "rl") +AnnotationAssertion( "2014-05-19T15:30:15Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of leukocyte adhesion") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of leukocyte cell adhesion") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of leukocyte adhesion") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of leukocyte cell adhesion") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of leukocyte cell-cell adhesion") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of leukocyte adhesion") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of leukocyte cell adhesion") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of leukocyte cell-cell adhesion") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of leukocyte adhesion") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of leukocyte cell adhesion") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of leukocyte cell-cell adhesion") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of leukocyte adhesion") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of leukocyte cell adhesion") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of leukocyte cell-cell adhesion") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1903039") +AnnotationAssertion(rdfs:comment "Exogenous expression of ASS1 or NOS3 in HUVECs enhances NO production and inhibits monocyte adhesion") +AnnotationAssertion(rdfs:label "positive regulation of leukocyte cell-cell adhesion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of chondrocyte hypertrophy) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mr") Annotation( "GO_REF:0000058") Annotation( "PMID:23928032") "Any process that modulates the frequency, rate or extent of chondrocyte hypertrophy.") +AnnotationAssertion( "mr") +AnnotationAssertion( "2014-05-20T21:23:13Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1903041") +AnnotationAssertion(rdfs:label "regulation of chondrocyte hypertrophy") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of chondrocyte hypertrophy) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mr") Annotation( "GO_REF:0000058") Annotation( "PMID:23928032") "Any process that stops, prevents or reduces the frequency, rate or extent of chondrocyte hypertrophy.") +AnnotationAssertion( "mr") +AnnotationAssertion( "2014-05-20T21:23:19Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of chondrocyte hypertrophy") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of chondrocyte hypertrophy") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of chondrocyte hypertrophy") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of chondrocyte hypertrophy") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1903042") +AnnotationAssertion(rdfs:label "negative regulation of chondrocyte hypertrophy") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of chondrocyte hypertrophy) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mr") Annotation( "GO_REF:0000058") Annotation( "PMID:23928032") "Any process that activates or increases the frequency, rate or extent of chondrocyte hypertrophy.") +AnnotationAssertion( "mr") +AnnotationAssertion( "2014-05-20T21:23:25Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of chondrocyte hypertrophy") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of chondrocyte hypertrophy") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of chondrocyte hypertrophy") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of chondrocyte hypertrophy") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1903043") +AnnotationAssertion(rdfs:label "positive regulation of chondrocyte hypertrophy") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (neural crest cell migration involved in sympathetic nervous system development) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "GO_REF:0000060") Annotation( "PMID:19325129") "Any neural crest cell migration that is involved in sympathetic nervous system development.") +AnnotationAssertion( "rl") +AnnotationAssertion( "2014-05-22T07:06:02Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1903045") +AnnotationAssertion(rdfs:comment "Sema3a (O08665, mouse) is involved in neural crest cell migration involved in sympathetic nervous system development") +AnnotationAssertion(rdfs:label "neural crest cell migration involved in sympathetic nervous system development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (meiotic cell cycle process) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mtg_cell_cycle") Annotation( "GO_REF:0000060") "A process that is part of the meiotic cell cycle.") +AnnotationAssertion( "jl") +AnnotationAssertion( "2014-05-22T14:22:28Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1903046") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "meiotic cell cycle process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +DisjointClasses( ) + +# Class: (mitotic cell cycle process) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mtg_cell_cycle") Annotation( "GO_REF:0000060") "A process that is part of the mitotic cell cycle.") +AnnotationAssertion( "jl") +AnnotationAssertion( "2014-05-22T14:22:34Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1903047") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "mitotic cell cycle process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of proteolysis involved in protein catabolic process) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "GO_REF:0000058") Annotation( "PMID:18307834") "Any process that modulates the frequency, rate or extent of proteolysis involved in cellular catabolic process.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/23112"^^xsd:anyURI) +AnnotationAssertion( "rl") +AnnotationAssertion( "2014-05-22T18:00:45Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of peptidolysis involved in cellular protein catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of peptidolysis involved in cellular protein catabolism") +AnnotationAssertion( "regulation of proteolysis involved in cellular protein catabolic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of peptidolysis during cellular protein catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of peptidolysis during cellular protein catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of proteolysis during cellular protein catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of proteolysis during cellular protein catabolism") +AnnotationAssertion( "GO:1903050") +AnnotationAssertion(rdfs:comment "overexpression of cathepsin C propeptide significantly increased the degradation of intestinal alkaline phosphatase (IAP)") +AnnotationAssertion(rdfs:label "regulation of proteolysis involved in protein catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of proteolysis involved in protein catabolic process) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "GO_REF:0000058") Annotation( "PMID:18307834") "Any process that stops, prevents or reduces the frequency, rate or extent of proteolysis involved in protein catabolic process.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/23112"^^xsd:anyURI) +AnnotationAssertion( "rl") +AnnotationAssertion( "2014-05-22T18:00:51Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of peptidolysis involved in cellular protein catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of peptidolysis involved in cellular protein catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of proteolysis involved in cellular protein catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of peptidolysis involved in cellular protein catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of peptidolysis involved in cellular protein catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of proteolysis involved in cellular protein catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of peptidolysis involved in cellular protein catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of peptidolysis involved in cellular protein catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of proteolysis involved in cellular protein catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of peptidolysis involved in cellular protein catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of peptidolysis involved in cellular protein catabolism") +AnnotationAssertion( "negative regulation of proteolysis involved in cellular protein catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of peptidolysis involved in cellular protein catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of peptidolysis involved in cellular protein catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of proteolysis involved in cellular protein catabolic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of peptidolysis during cellular protein catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of peptidolysis during cellular protein catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of proteolysis during cellular protein catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of proteolysis during cellular protein catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of peptidolysis during cellular protein catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of peptidolysis during cellular protein catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of proteolysis during cellular protein catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of proteolysis during cellular protein catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of peptidolysis during cellular protein catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of peptidolysis during cellular protein catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of proteolysis during cellular protein catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of proteolysis during cellular protein catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of peptidolysis during cellular protein catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of peptidolysis during cellular protein catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of proteolysis during cellular protein catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of proteolysis during cellular protein catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of peptidolysis during cellular protein catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of peptidolysis during cellular protein catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of proteolysis during cellular protein catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of proteolysis during cellular protein catabolism") +AnnotationAssertion( "GO:1903051") +AnnotationAssertion(rdfs:comment "Overexpression of cathepsin C propeptide significantly increased the degradation of intestinal alkaline phosphatase (IAP).") +AnnotationAssertion(rdfs:label "negative regulation of proteolysis involved in protein catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of proteolysis involved in protein catabolic process) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "GO_REF:0000058") Annotation( "PMID:18307834") "Any process that activates or increases the frequency, rate or extent of proteolysis involved in protein catabolic process.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/23112"^^xsd:anyURI) +AnnotationAssertion( "rl") +AnnotationAssertion( "2014-05-22T18:00:57Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of peptidolysis involved in cellular protein catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of peptidolysis involved in cellular protein catabolism") +AnnotationAssertion( "positive regulation of proteolysis involved in cellular protein catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of peptidolysis involved in cellular protein catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of peptidolysis involved in cellular protein catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of proteolysis involved in cellular protein catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of peptidolysis involved in cellular protein catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of peptidolysis involved in cellular protein catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of proteolysis involved in cellular protein catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of peptidolysis involved in cellular protein catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of peptidolysis involved in cellular protein catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of proteolysis involved in cellular protein catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of peptidolysis involved in cellular protein catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of peptidolysis involved in cellular protein catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of proteolysis involved in cellular protein catabolic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of peptidolysis during cellular protein catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of peptidolysis during cellular protein catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of proteolysis during cellular protein catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of proteolysis during cellular protein catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of peptidolysis during cellular protein catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of peptidolysis during cellular protein catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of proteolysis during cellular protein catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of proteolysis during cellular protein catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of peptidolysis during cellular protein catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of peptidolysis during cellular protein catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of proteolysis during cellular protein catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of proteolysis during cellular protein catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of peptidolysis during cellular protein catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of peptidolysis during cellular protein catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of proteolysis during cellular protein catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of proteolysis during cellular protein catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of peptidolysis during cellular protein catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of peptidolysis during cellular protein catabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of proteolysis during cellular protein catabolic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of proteolysis during cellular protein catabolism") +AnnotationAssertion( "GO:1903052") +AnnotationAssertion(rdfs:comment "overexpression of cathepsin C propeptide significantly increased the degradation of intestinal alkaline phosphatase (IAP)") +AnnotationAssertion(rdfs:label "positive regulation of proteolysis involved in protein catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of extracellular matrix organization) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "GO_REF:0000058") Annotation( "PMID:22357537") "Any process that modulates the frequency, rate or extent of extracellular matrix organization.") +AnnotationAssertion( "rl") +AnnotationAssertion( "2014-05-23T17:15:41Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of extracellular matrix organisation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of extracellular matrix organization and biogenesis") +AnnotationAssertion( "GO:1903053") +AnnotationAssertion(rdfs:label "regulation of extracellular matrix organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (negative regulation of extracellular matrix organization) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "GO_REF:0000058") Annotation( "PMID:22357537") "Any process that stops, prevents or reduces the frequency, rate or extent of extracellular matrix organization.") +AnnotationAssertion( "rl") +AnnotationAssertion( "2014-05-23T17:15:47Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of extracellular matrix organisation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of extracellular matrix organization") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of extracellular matrix organisation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of extracellular matrix organization") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of extracellular matrix organisation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of extracellular matrix organization") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of extracellular matrix organisation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of extracellular matrix organisation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of extracellular matrix organization") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of extracellular matrix organization and biogenesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of extracellular matrix organization and biogenesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of extracellular matrix organization and biogenesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of extracellular matrix organization and biogenesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of extracellular matrix organization and biogenesis") +AnnotationAssertion( "GO:1903054") +AnnotationAssertion(rdfs:label "negative regulation of extracellular matrix organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of extracellular matrix organization) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "GO_REF:0000058") Annotation( "PMID:22357537") "Any process that activates or increases the frequency, rate or extent of extracellular matrix organization.") +AnnotationAssertion( "rl") +AnnotationAssertion( "2014-05-23T17:15:53Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of extracellular matrix organisation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of extracellular matrix organisation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of extracellular matrix organization") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of extracellular matrix organisation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of extracellular matrix organization") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of extracellular matrix organisation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of extracellular matrix organization") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of extracellular matrix organisation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of extracellular matrix organization") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of extracellular matrix organization and biogenesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of extracellular matrix organization and biogenesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of extracellular matrix organization and biogenesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of extracellular matrix organization and biogenesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of extracellular matrix organization and biogenesis") +AnnotationAssertion( "GO:1903055") +AnnotationAssertion(rdfs:label "positive regulation of extracellular matrix organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of melanosome organization) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "GO_REF:0000058") Annotation( "PMID:24769727") "Any process that modulates the frequency, rate or extent of melanosome organization.") +AnnotationAssertion( "rl") +AnnotationAssertion( "2014-05-27T13:27:49Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of melanosome organisation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of melanosome organization and biogenesis") +AnnotationAssertion( "GO:1903056") +AnnotationAssertion(rdfs:comment "Lack of the transcription factor Zeb2 Q9R0G7 leads to spherical melanosomes with irregular borders, in contrast to the rod-shaped melanosomes of ZEB2MCWT hair follicles") +AnnotationAssertion(rdfs:label "regulation of melanosome organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of melanosome organization) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "GO_REF:0000058") Annotation( "PMID:24769727") "Any process that stops, prevents or reduces the frequency, rate or extent of melanosome organization.") +AnnotationAssertion( "rl") +AnnotationAssertion( "2014-05-27T13:27:55Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of melanosome organisation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of melanosome organization") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of melanosome organisation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of melanosome organization") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of melanosome organisation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of melanosome organization") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of melanosome organisation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of melanosome organisation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of melanosome organization") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of melanosome organization and biogenesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of melanosome organization and biogenesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of melanosome organization and biogenesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of melanosome organization and biogenesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of melanosome organization and biogenesis") +AnnotationAssertion( "GO:1903057") +AnnotationAssertion(rdfs:comment "Lack of the transcription factor Zeb2 Q9R0G7 leads to spherical melanosomes with irregular borders, in contrast to the rod-shaped melanosomes of ZEB2MCWT hair follicles.") +AnnotationAssertion(rdfs:label "negative regulation of melanosome organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of melanosome organization) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "GO_REF:0000058") Annotation( "PMID:24769727") "Any process that activates or increases the frequency, rate or extent of melanosome organization.") +AnnotationAssertion( "rl") +AnnotationAssertion( "2014-05-27T13:28:01Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of melanosome organisation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of melanosome organisation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of melanosome organization") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of melanosome organisation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of melanosome organization") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of melanosome organisation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of melanosome organization") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of melanosome organisation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of melanosome organization") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of melanosome organization and biogenesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of melanosome organization and biogenesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of melanosome organization and biogenesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of melanosome organization and biogenesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of melanosome organization and biogenesis") +AnnotationAssertion( "GO:1903058") +AnnotationAssertion(rdfs:comment "Lack of the transcription factor Zeb2 Q9R0G7 leads to spherical melanosomes with irregular borders, in contrast to the rod-shaped melanosomes of ZEB2MCWT hair follicles.") +AnnotationAssertion(rdfs:label "positive regulation of melanosome organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of protein localization to plasma membrane) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "GO_REF:0000058") Annotation( "PMID:11602640") "Any process that modulates the frequency, rate or extent of protein localization to plasma membrane.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2009-07-10T10:32:44Z") +AnnotationAssertion( "GO:0090003") +AnnotationAssertion( "GO:1905963") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of protein localization in plasma membrane") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:mah") "regulation of establishment of protein localisation in plasma membrane") +AnnotationAssertion( "regulation of establishment of protein localization in plasma membrane") +AnnotationAssertion( "regulation of establishment of protein localization to plasma membrane") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of protein localisation in plasma membrane") +AnnotationAssertion( "regulation of protein targeting to plasma membrane") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of protein-plasma membrane targeting") +AnnotationAssertion( "GO:1903076") +AnnotationAssertion(rdfs:label "regulation of protein localization to plasma membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of protein localization to plasma membrane) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "GO_REF:0000058") Annotation( "PMID:11602640") "Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to plasma membrane.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2014-05-29T17:10:16Z") +AnnotationAssertion( "GO:0090005") +AnnotationAssertion( "GO:1905964") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of protein localisation in plasma membrane") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of protein localization in plasma membrane") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of protein localization to plasma membrane") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of protein localisation in plasma membrane") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of protein localization in plasma membrane") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of protein localization to plasma membrane") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of protein localisation in plasma membrane") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of protein localization in plasma membrane") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of protein localization to plasma membrane") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of protein localization in plasma membrane") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of protein localisation in plasma membrane") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of protein localization in plasma membrane") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of protein localization to plasma membrane") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of protein targeting to plasma membrane") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of protein-plasma membrane targeting") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of protein targeting to plasma membrane") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of protein-plasma membrane targeting") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of protein targeting to plasma membrane") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of protein-plasma membrane targeting") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of protein targeting to plasma membrane") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of protein-plasma membrane targeting") +AnnotationAssertion(Annotation( "GOC:mah") "negative regulation of establishment of protein localisation in plasma membrane") +AnnotationAssertion( "negative regulation of establishment of protein localization in plasma membrane") +AnnotationAssertion( "negative regulation of establishment of protein localization to plasma membrane") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of protein localisation in plasma membrane") +AnnotationAssertion( "negative regulation of protein targeting to plasma membrane") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of protein-plasma membrane targeting") +AnnotationAssertion( "GO:1903077") +AnnotationAssertion(rdfs:label "negative regulation of protein localization to plasma membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of protein localization to plasma membrane) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "GO_REF:0000058") Annotation( "PMID:11602640") "Any process that activates or increases the frequency, rate or extent of protein localization to plasma membrane.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2009-07-10T10:34:17Z") +AnnotationAssertion( "GO:0090004") +AnnotationAssertion( "GO:1905965") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of protein localisation in plasma membrane") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of protein localization in plasma membrane") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of protein localisation in plasma membrane") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of protein localization in plasma membrane") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of protein localization to plasma membrane") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of protein localisation in plasma membrane") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of protein localization in plasma membrane") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of protein localization to plasma membrane") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of protein localisation in plasma membrane") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of protein localization in plasma membrane") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of protein localization to plasma membrane") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of protein localisation in plasma membrane") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of protein localization in plasma membrane") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of protein localization to plasma membrane") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of protein targeting to plasma membrane") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of protein-plasma membrane targeting") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:mah") "positive regulation of establishment of protein localisation in plasma membrane") +AnnotationAssertion( "positive regulation of establishment of protein localization to plasma membrane") +AnnotationAssertion( "positive regulation of protein targeting to plasma membrane") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of protein-plasma membrane targeting") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of protein targeting to plasma membrane") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of protein-plasma membrane targeting") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of protein targeting to plasma membrane") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of protein-plasma membrane targeting") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of protein targeting to plasma membrane") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of protein-plasma membrane targeting") +AnnotationAssertion( "GO:1903078") +AnnotationAssertion(rdfs:label "positive regulation of protein localization to plasma membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of actin filament-based movement) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:24798735") "Any process that modulates the frequency, rate or extent of actin filament-based movement.") +AnnotationAssertion( "al") +AnnotationAssertion( "2014-06-12T16:55:57Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1903115") +AnnotationAssertion(rdfs:label "regulation of actin filament-based movement") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of actin filament-based movement) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:24798735") "Any process that activates or increases the frequency, rate or extent of actin filament-based movement.") +AnnotationAssertion( "al") +AnnotationAssertion( "2014-06-12T16:56:04Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of actin filament-based movement") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of actin filament-based movement") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of actin filament-based movement") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of actin filament-based movement") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1903116") +AnnotationAssertion(rdfs:label "positive regulation of actin filament-based movement") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (protein localization to actin cytoskeleton) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000087") Annotation( "PMID:24798735") "A process in which a protein is transported to, or maintained in, the location of an actin cytoskeleton.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2014-06-16T11:27:09Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "protein localisation in actin cytoskeleton") +AnnotationAssertion(Annotation( "GOC:TermGenie") "protein localisation to actin cytoskeleton") +AnnotationAssertion(Annotation( "GOC:TermGenie") "protein localization in actin cytoskeleton") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1903119") +AnnotationAssertion(rdfs:label "protein localization to actin cytoskeleton") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (protein localization to actin filament bundle) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000087") Annotation( "PMID:24798735") "A process in which a protein is transported to, or maintained in, the location of an actin filament bundle.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2014-06-16T11:27:16Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "protein localisation in actin filament bundle") +AnnotationAssertion(Annotation( "GOC:TermGenie") "protein localisation to actin filament bundle") +AnnotationAssertion(Annotation( "GOC:TermGenie") "protein localization in actin filament bundle") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:mah") "protein localization to actin cable") +AnnotationAssertion( "GO:1903120") +AnnotationAssertion(rdfs:label "protein localization to actin filament bundle") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (mononuclear cell differentiation) + +AnnotationAssertion(Annotation( "CL:0000842") Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000086") Annotation( "PMID:24759906") "The process in which a relatively unspecialized cell acquires the specialized features of a mononuclear cell.") +AnnotationAssertion( "cls") +AnnotationAssertion( "2014-06-25T15:47:09Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1903131") +AnnotationAssertion(rdfs:label "mononuclear cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of calcium ion transmembrane transport) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "GO_REF:0000058") Annotation( "PMID:24125847") "Any process that modulates the frequency, rate or extent of calcium ion transmembrane transport.") +AnnotationAssertion( "rl") +AnnotationAssertion( "2014-07-11T17:09:26Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of calcium ion membrane transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of transmembrane calcium transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1903169") +AnnotationAssertion(rdfs:comment "human HRC regulates RYR2 and thus regulates transmembrane transport of calcium from SR to cytosol") +AnnotationAssertion(rdfs:label "regulation of calcium ion transmembrane transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of calcium ion transmembrane transport) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "GO_REF:0000058") Annotation( "PMID:24125847") "Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion transmembrane transport.") +AnnotationAssertion( "rl") +AnnotationAssertion( "2014-07-11T17:09:32Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of calcium ion membrane transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of calcium ion transmembrane transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of transmembrane calcium transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of calcium ion membrane transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of calcium ion transmembrane transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of transmembrane calcium transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of calcium ion membrane transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of calcium ion transmembrane transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of transmembrane calcium transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of calcium ion membrane transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of transmembrane calcium transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of calcium ion membrane transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of calcium ion transmembrane transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of transmembrane calcium transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1903170") +AnnotationAssertion(rdfs:comment "human HRC regulates RYR2 and thus regulates transmembrane transport of calcium from SR to cytosol") +AnnotationAssertion(rdfs:label "negative regulation of calcium ion transmembrane transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of dopamine biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:TermGenie") Annotation( "GOC:bf") Annotation( "GO_REF:0000058") "Any process that modulates the frequency, rate or extent of dopamine biosynthetic process.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2014-07-14T12:17:41Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of dopamine anabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of dopamine biosynthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of dopamine formation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of dopamine synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1903179") +AnnotationAssertion(rdfs:label "regulation of dopamine biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of dopamine biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:TermGenie") Annotation( "GOC:bf") Annotation( "GO_REF:0000058") "Any process that stops, prevents or reduces the frequency, rate or extent of dopamine biosynthetic process.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2014-07-14T12:17:47Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of dopamine anabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of dopamine biosynthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of dopamine biosynthetic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of dopamine formation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of dopamine synthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of dopamine anabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of dopamine biosynthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of dopamine biosynthetic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of dopamine formation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of dopamine synthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of dopamine anabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of dopamine biosynthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of dopamine biosynthetic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of dopamine formation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of dopamine synthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of dopamine anabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of dopamine biosynthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of dopamine formation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of dopamine synthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of dopamine anabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of dopamine biosynthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of dopamine biosynthetic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of dopamine formation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of dopamine synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1903180") +AnnotationAssertion(rdfs:label "negative regulation of dopamine biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of dopamine biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:TermGenie") Annotation( "GOC:bf") Annotation( "GO_REF:0000058") Annotation( "PMID:19703902") "Any process that activates or increases the frequency, rate or extent of dopamine biosynthetic process.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2014-07-14T12:17:53Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of dopamine anabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of dopamine biosynthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of dopamine formation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of dopamine synthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of dopamine anabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of dopamine biosynthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of dopamine biosynthetic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of dopamine formation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of dopamine synthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of dopamine anabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of dopamine biosynthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of dopamine biosynthetic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of dopamine formation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of dopamine synthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of dopamine anabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of dopamine biosynthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of dopamine biosynthetic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of dopamine formation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of dopamine synthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of dopamine anabolism") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of dopamine biosynthesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of dopamine biosynthetic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of dopamine formation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of dopamine synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1903181") +AnnotationAssertion(rdfs:label "positive regulation of dopamine biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (podocyte apoptotic process) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000085") Annotation( "PMID:23515840") "Any apoptotic process in a glomerular visceral epithelial cell.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/23000"^^xsd:anyURI) +AnnotationAssertion( "sl") +AnnotationAssertion( "2014-07-23T17:07:55Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "glomerular podocyte apoptotic process") +AnnotationAssertion( "glomerular visceral epithelial cell apoptotic process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "glomerular podocyte apoptosis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "glomerular visceral epithelial cell apoptosis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "podocyte apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1903210") +AnnotationAssertion(rdfs:label "podocyte apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of endodermal cell differentiation) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:als") Annotation( "GO_REF:0000058") Annotation( "PMID:23154389") "Any process that modulates the frequency, rate or extent of endodermal cell differentiation.") +AnnotationAssertion( "als") +AnnotationAssertion( "2014-07-29T13:22:35Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of endoderm cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1903224") +AnnotationAssertion(rdfs:label "regulation of endodermal cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of endodermal cell differentiation) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:als") Annotation( "GO_REF:0000058") Annotation( "PMID:23154389") "Any process that stops, prevents or reduces the frequency, rate or extent of endodermal cell differentiation.") +AnnotationAssertion( "als") +AnnotationAssertion( "2014-07-29T13:22:41Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of endoderm cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of endodermal cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of endoderm cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of endodermal cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of endoderm cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of endodermal cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of endoderm cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of endoderm cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of endodermal cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1903225") +AnnotationAssertion(rdfs:label "negative regulation of endodermal cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of endodermal cell differentiation) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:als") Annotation( "GO_REF:0000058") Annotation( "PMID:23154389") "Any process that activates or increases the frequency, rate or extent of endodermal cell differentiation.") +AnnotationAssertion( "als") +AnnotationAssertion( "2014-07-29T13:22:47Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of endoderm cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of endoderm cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of endodermal cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of endoderm cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of endodermal cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of endoderm cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of endodermal cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of endoderm cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of endodermal cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1903226") +AnnotationAssertion(rdfs:label "positive regulation of endodermal cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (melanosome assembly) + +AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:TermGenie") Annotation( "GOC:bf") Annotation( "GO_REF:0000079") Annotation( "PMID:22511774") "The aggregation, arrangement and bonding together of a set of components to form a melanosome, a tissue-specific, membrane-bounded cytoplasmic organelle within which melanin pigments are synthesized and stored.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2014-07-31T10:41:38Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "melanosome formation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1903232") +AnnotationAssertion(rdfs:label "melanosome assembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (multi-ciliated epithelial cell differentiation) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:sp") Annotation( "GO_REF:0000086") Annotation( "PMID:22231168") Annotation( "PMID:24934224") "The process in which a relatively unspecialized cell acquires the specialized features of a multi-ciliated epithelial cell.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2014-08-05T19:21:21Z") +AnnotationAssertion( "multiciliate cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1903251") +AnnotationAssertion(rdfs:label "multi-ciliated epithelial cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of sodium ion export across plasma membrane) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "GO_REF:0000058") Annotation( "PMID:17095720") "Any process that modulates the frequency, rate or extent of sodium ion export across the plasma membrane.") +AnnotationAssertion( "rl") +AnnotationAssertion( "2014-08-08T17:06:46Z") +AnnotationAssertion( "GO:1903273") +AnnotationAssertion( "regulation of sodium ion export from cell") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of sodium export") +AnnotationAssertion( "regulation of sodium ion export") +AnnotationAssertion( "GO:1903276") +AnnotationAssertion(rdfs:label "regulation of sodium ion export across plasma membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of sodium ion export across plasma membrane) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "GO_REF:0000058") Annotation( "PMID:17095720") "Any process that stops, prevents or reduces the frequency, rate or extent of sodium ion export across the plasma membrane.") +AnnotationAssertion( "rl") +AnnotationAssertion( "2014-08-08T17:10:22Z") +AnnotationAssertion( "GO:1903274") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of sodium ion export from cell") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of sodium ion export from cell") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of sodium ion export from cell") +AnnotationAssertion( "negative regulation of sodium ion export from cell") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of sodium export") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of sodium ion export") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of sodium ion export from cell") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of sodium export") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of sodium ion export") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of sodium export") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of sodium ion export") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of sodium export") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of sodium ion export") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of sodium export") +AnnotationAssertion( "negative regulation of sodium ion export") +AnnotationAssertion( "GO:1903277") +AnnotationAssertion(rdfs:label "negative regulation of sodium ion export across plasma membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of sodium ion export across plasma membrane) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "GO_REF:0000058") Annotation( "PMID:17095720") "Any process that activates or increases the frequency, rate or extent of sodium ion export across the plasma membrane.") +AnnotationAssertion( "rl") +AnnotationAssertion( "2014-08-08T17:10:30Z") +AnnotationAssertion( "GO:1903275") +AnnotationAssertion( "positive regulation of sodium ion export from cell") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of sodium ion export from cell") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of sodium ion export from cell") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of sodium ion export from cell") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of sodium export") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of sodium ion export") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of sodium ion export from cell") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of sodium export") +AnnotationAssertion( "positive regulation of sodium ion export") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of sodium export") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of sodium ion export") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of sodium export") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of sodium ion export") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of sodium export") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of sodium ion export") +AnnotationAssertion( "GO:1903278") +AnnotationAssertion(rdfs:label "positive regulation of sodium ion export across plasma membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (protein localization to Golgi membrane) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000087") Annotation( "PMID:11378902") "A process in which a protein is transported to, or maintained in, a location within a Golgi membrane.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2014-08-12T14:22:31Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "protein localisation in Golgi membrane") +AnnotationAssertion(Annotation( "GOC:TermGenie") "protein localisation to Golgi membrane") +AnnotationAssertion(Annotation( "GOC:TermGenie") "protein localization in Golgi membrane") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1903292") +AnnotationAssertion(rdfs:label "protein localization to Golgi membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of glutamate secretion, neurotransmission) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:16782817") "Any process that modulates the frequency, rate or extent of glutamate secretion, neurotransmission.") +AnnotationAssertion( "pad") +AnnotationAssertion( "2014-08-13T13:54:15Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1903294") +AnnotationAssertion(rdfs:comment "An example of this is Rab3gap1 in mouse (Q80UJ7) in PMID:16782817 inferred from mutant phenotype") +AnnotationAssertion(rdfs:label "regulation of glutamate secretion, neurotransmission") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (negative regulation of glutamate secretion, neurotransmission) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:16782817") "Any process that stops, prevents or reduces the frequency, rate or extent of glutamate secretion, neurotransmission.") +AnnotationAssertion( "pad") +AnnotationAssertion( "2014-08-13T13:54:23Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of glutamate secretion, neurotransmission") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of glutamate secretion, neurotransmission") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of glutamate secretion, neurotransmission") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of glutamate secretion, neurotransmission") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1903295") +AnnotationAssertion(rdfs:comment "An example of this is Rab3gap1 in mouse (Q80UJ7) in PMID:16782817 inferred from mutant phenotype") +AnnotationAssertion(rdfs:label "negative regulation of glutamate secretion, neurotransmission") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (positive regulation of glutamate secretion, neurotransmission) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:16782817") "Any process that activates or increases the frequency, rate or extent of glutamate secretion, where glutamate acts as a neurotransmitter.") +AnnotationAssertion( "pad") +AnnotationAssertion( "2014-08-13T13:54:31Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of glutamate secretion, neurotransmission") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of glutamate secretion, neurotransmission") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of glutamate secretion, neurotransmission") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of glutamate secretion, neurotransmission") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1903296") +AnnotationAssertion(rdfs:comment "An example of this is Rab3gap1 in mouse (Q80UJ7) in PMID:16782817 inferred from mutant phenotype") +AnnotationAssertion(rdfs:label "positive regulation of glutamate secretion, neurotransmission") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (regulation of regulated secretory pathway) + +AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:TermGenie") Annotation( "GOC:pad") Annotation( "GO_REF:0000058") Annotation( "PMID:12526776") "Any process that modulates the frequency, rate or extent of regulated secretory pathway.") +AnnotationAssertion( "pad") +AnnotationAssertion( "2014-08-18T10:04:53Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1903305") +AnnotationAssertion(rdfs:comment "An example of this is protein domain-specific expression of Synaptotagmin 1 in rat (P21707) in PMID:12526776 inferred from mutant phenotype.") +AnnotationAssertion(rdfs:label "regulation of regulated secretory pathway") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of regulated secretory pathway) + +AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:TermGenie") Annotation( "GOC:pad") Annotation( "GO_REF:0000058") Annotation( "PMID:12526776") "Any process that stops, prevents or reduces the frequency, rate or extent of regulated secretory pathway.") +AnnotationAssertion( "pad") +AnnotationAssertion( "2014-08-18T10:05:02Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of regulated secretory pathway") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of regulated secretory pathway") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of regulated secretory pathway") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of regulated secretory pathway") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1903306") +AnnotationAssertion(rdfs:comment "An example of this is protein domain-specific expression of Synaptotagmin 1 in rat (P21707) in PMID:12526776 inferred from mutant phenotype.") +AnnotationAssertion(rdfs:label "negative regulation of regulated secretory pathway") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of regulated secretory pathway) + +AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:TermGenie") Annotation( "GOC:pad") Annotation( "GO_REF:0000058") Annotation( "PMID:12526776") "Any process that activates or increases the frequency, rate or extent of regulated secretory pathway.") +AnnotationAssertion( "pad") +AnnotationAssertion( "2014-08-18T10:05:10Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of regulated secretory pathway") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of regulated secretory pathway") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of regulated secretory pathway") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of regulated secretory pathway") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1903307") +AnnotationAssertion(rdfs:comment "An example of this is protein domain-specific expression of Synaptotagmin 1 in rat (P21707) in PMID:12526776 inferred from mutant phenotype.") +AnnotationAssertion(rdfs:label "positive regulation of regulated secretory pathway") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of protein maturation) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:vw") Annotation( "GO_REF:0000058") "Any process that modulates the frequency, rate or extent of protein maturation.") +AnnotationAssertion( "vw") +AnnotationAssertion( "2014-08-18T12:59:07Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1903317") +AnnotationAssertion(rdfs:label "regulation of protein maturation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (negative regulation of protein maturation) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:vw") Annotation( "GO_REF:0000058") "Any process that stops, prevents or reduces the frequency, rate or extent of protein maturation.") +AnnotationAssertion( "vw") +AnnotationAssertion( "2014-08-18T12:59:15Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of protein maturation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of protein maturation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of protein maturation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of protein maturation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1903318") +AnnotationAssertion(rdfs:label "negative regulation of protein maturation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (positive regulation of protein maturation) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:vw") Annotation( "GO_REF:0000058") "Any process that activates or increases the frequency, rate or extent of protein maturation.") +AnnotationAssertion( "vw") +AnnotationAssertion( "2014-08-18T12:59:23Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of protein maturation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of protein maturation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of protein maturation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of protein maturation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1903319") +AnnotationAssertion(rdfs:label "positive regulation of protein maturation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (regulation of vacuolar transport) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:vw") Annotation( "GO_REF:0000058") "Any process that modulates the frequency, rate or extent of vacuolar transport.") +AnnotationAssertion( "vw") +AnnotationAssertion( "2014-08-18T13:16:04Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1903335") +AnnotationAssertion(rdfs:label "regulation of vacuolar transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of vacuolar transport) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:vw") Annotation( "GO_REF:0000058") "Any process that stops, prevents or reduces the frequency, rate or extent of vacuolar transport.") +AnnotationAssertion( "vw") +AnnotationAssertion( "2014-08-18T13:16:11Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of vacuolar transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of vacuolar transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of vacuolar transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of vacuolar transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1903336") +AnnotationAssertion(rdfs:label "negative regulation of vacuolar transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of vacuolar transport) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:vw") Annotation( "GO_REF:0000058") "Any process that activates or increases the frequency, rate or extent of vacuolar transport.") +AnnotationAssertion( "vw") +AnnotationAssertion( "2014-08-18T13:16:19Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of vacuolar transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of vacuolar transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of vacuolar transport") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of vacuolar transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1903337") +AnnotationAssertion(rdfs:label "positive regulation of vacuolar transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of bicellular tight junction assembly) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:jz") Annotation( "GO_REF:0000058") Annotation( "PMID:25050009") "Any process that stops, prevents or reduces the frequency, rate or extent of tight junction assembly.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2014-08-19T11:02:14Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of tight junction assembly") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of tight junction formation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of tight junction assembly") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of tight junction formation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of tight junction assembly") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of tight junction formation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of tight junction formation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of tight junction assembly") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of tight junction formation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1903347") +AnnotationAssertion(rdfs:label "negative regulation of bicellular tight junction assembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of bicellular tight junction assembly) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:jz") Annotation( "GO_REF:0000058") Annotation( "PMID:25050009") "Any process that activates or increases the frequency, rate or extent of tight junction assembly.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2014-08-19T11:05:06Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of tight junction formation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of tight junction assembly") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of tight junction formation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of tight junction assembly") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of tight junction formation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of tight junction assembly") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of tight junction formation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of tight junction assembly") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of tight junction formation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1903348") +AnnotationAssertion(rdfs:label "positive regulation of bicellular tight junction assembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (response to dopamine) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mr") Annotation( "GO_REF:0000071") Annotation( "PMID:11118945") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dopamine stimulus.") +AnnotationAssertion( "mr") +AnnotationAssertion( "2014-08-19T19:33:26Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1903350") +AnnotationAssertion(rdfs:label "response to dopamine") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (cellular response to dopamine) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mr") Annotation( "GO_REF:0000071") Annotation( "PMID:11118945") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dopamine stimulus.") +AnnotationAssertion( "mr") +AnnotationAssertion( "2014-08-19T19:33:35Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1903351") +AnnotationAssertion(rdfs:label "cellular response to dopamine") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of nucleus organization) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:16943282") "Any process that modulates the frequency, rate or extent of nucleus organization.") +AnnotationAssertion( "hjd") +AnnotationAssertion( "2014-08-20T19:36:16Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of nuclear organisation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of nuclear organization") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of nuclear morphology") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of nuclear organization and biogenesis") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of nucleus organization and biogenesis") +AnnotationAssertion( "GO:1903353") +AnnotationAssertion(rdfs:label "regulation of nucleus organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of Golgi organization) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:als") Annotation( "GO_REF:0000058") Annotation( "PMID:17562788") "Any process that modulates the frequency, rate or extent of Golgi organization.") +AnnotationAssertion( "als") +AnnotationAssertion( "2014-08-21T10:22:22Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of Golgi organisation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of Golgi organization and biogenesis") +AnnotationAssertion( "GO:1903358") +AnnotationAssertion(rdfs:label "regulation of Golgi organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (facioacoustic ganglion development) + +AnnotationAssertion(Annotation( "GOC:PARL") Annotation( "GOC:TermGenie") Annotation( "GOC:bf") Annotation( "GOC:mat") Annotation( "GO_REF:0000094") Annotation( "PMID:18356247") "The process whose specific outcome is the progression of an acoustico-facial VII-VIII ganglion complex over time, from its formation to the mature structure.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2014-08-26T12:40:36Z") +AnnotationAssertion(Annotation( "UBERON:0012175") "acoustico-facial VII-VIII ganglion complex development") +AnnotationAssertion(Annotation( "GOC:TermGenie") "acousticofacial ganglion development") +AnnotationAssertion(Annotation( "GOC:TermGenie") "facio-acoustic VII-VIII ganglion complex development") +AnnotationAssertion(Annotation( "GOC:TermGenie") "facio-acoustic ganglion complex VII-VIII development") +AnnotationAssertion(Annotation( "GOC:TermGenie") "facio-acoustic ganglion development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1903375") +AnnotationAssertion(rdfs:label "facioacoustic ganglion development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of mitotic chromosome condensation) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:9490640") "Any process that modulates the frequency, rate or extent of mitotic chromosome condensation.") +AnnotationAssertion( "al") +AnnotationAssertion( "2014-08-26T13:57:13Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1903379") +AnnotationAssertion(rdfs:label "regulation of mitotic chromosome condensation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of mitotic chromosome condensation) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:9490640") "Any process that activates or increases the frequency, rate or extent of mitotic chromosome condensation.") +AnnotationAssertion( "al") +AnnotationAssertion( "2014-08-26T13:57:29Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of mitotic chromosome condensation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of mitotic chromosome condensation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of mitotic chromosome condensation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of mitotic chromosome condensation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1903380") +AnnotationAssertion(rdfs:label "positive regulation of mitotic chromosome condensation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (response to bile acid) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "GO_REF:0000071") Annotation( "PMID:21757002") "Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bile acid stimulus.") +AnnotationAssertion( "rl") +AnnotationAssertion( "2014-09-03T12:45:43Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1903412") +AnnotationAssertion(rdfs:label "response to bile acid") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (cellular response to bile acid) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:TermGenie") Annotation( "GOC:rl") Annotation( "GO_REF:0000071") Annotation( "PMID:21757002") "Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bile acid stimulus.") +AnnotationAssertion( "rl") +AnnotationAssertion( "2014-09-03T12:45:51Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1903413") +AnnotationAssertion(rdfs:label "cellular response to bile acid") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of cell maturation) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:17459944") "Any process that modulates the frequency, rate or extent of cell maturation.") +AnnotationAssertion( "jl") +AnnotationAssertion( "2014-09-15T13:31:23Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "regulation of functional differentiation") +AnnotationAssertion( "GO:1903429") +AnnotationAssertion(rdfs:label "regulation of cell maturation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (negative regulation of cell maturation) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:17459944") "Any process that stops, prevents or reduces the frequency, rate or extent of cell maturation.") +AnnotationAssertion( "jl") +AnnotationAssertion( "2014-09-15T13:31:32Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of cell maturation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of cell maturation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of cell maturation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of cell maturation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of functional differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of functional differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of functional differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of functional differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of functional differentiation") +AnnotationAssertion( "GO:1903430") +AnnotationAssertion(rdfs:label "negative regulation of cell maturation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of cell maturation) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:17459944") "Any process that activates or increases the frequency, rate or extent of cell maturation.") +AnnotationAssertion( "jl") +AnnotationAssertion( "2014-09-15T13:31:41Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of cell maturation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of cell maturation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of cell maturation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of cell maturation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of functional differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of functional differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of functional differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of functional differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of functional differentiation") +AnnotationAssertion( "GO:1903431") +AnnotationAssertion(rdfs:label "positive regulation of cell maturation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (calcitonin family receptor complex) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:bhm") Annotation( "GO_REF:0000088") Annotation( "PMID:10871296") Annotation( "PMID:12037140") Annotation( "PMID:18687416") "A protein complex which is capable of calcitonin family receptor activity. Calcitonin family receptors may form dimers, trimers or tetramers; adrenomedullin and amylin receptors have only been observed as dimers so far.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2014-09-16T13:25:11Z") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:1903439") +AnnotationAssertion(rdfs:label "calcitonin family receptor complex") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (protein localization to ciliary membrane) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:cilia") Annotation( "GOC:krc") Annotation( "GO_REF:0000087") Annotation( "PMID:22139371") "A process in which a protein is transported to, or maintained in, a location within a ciliary membrane.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2014-09-16T15:15:39Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "protein localisation in ciliary membrane") +AnnotationAssertion(Annotation( "GOC:TermGenie") "protein localisation to ciliary membrane") +AnnotationAssertion(Annotation( "GOC:TermGenie") "protein localization in ciliary membrane") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1903441") +AnnotationAssertion(rdfs:label "protein localization to ciliary membrane") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of brown fat cell differentiation) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000058") Annotation( "PMID:23977283") "Any process that stops, prevents or reduces the frequency, rate or extent of brown fat cell differentiation.") +AnnotationAssertion( "hjd") +AnnotationAssertion( "2014-09-17T19:15:00Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of brown adipocyte cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of brown adipocyte differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of brown fat cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of brown adipocyte cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of brown adipocyte differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of brown fat cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of brown adipocyte cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of brown adipocyte differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of brown fat cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of brown adipocyte cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of brown adipocyte differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of brown adipocyte cell differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of brown adipocyte differentiation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of brown fat cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1903444") +AnnotationAssertion(rdfs:label "negative regulation of brown fat cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of lactation) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mr") Annotation( "GO_REF:0000058") Annotation( "PMID:19563620") "Any process that modulates the frequency, rate or extent of lactation.") +AnnotationAssertion( "mr") +AnnotationAssertion( "2014-09-24T14:44:13Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1903487") +AnnotationAssertion(rdfs:label "regulation of lactation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of lactation) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mr") Annotation( "GO_REF:0000058") Annotation( "PMID:19563620") "Any process that stops, prevents or reduces the frequency, rate or extent of lactation.") +AnnotationAssertion( "mr") +AnnotationAssertion( "2014-09-24T14:44:22Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of lactation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of lactation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of lactation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of lactation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1903488") +AnnotationAssertion(rdfs:label "negative regulation of lactation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of lactation) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mr") Annotation( "GO_REF:0000058") Annotation( "PMID:19563620") "Any process that activates or increases the frequency, rate or extent of lactation.") +AnnotationAssertion( "mr") +AnnotationAssertion( "2014-09-24T14:44:30Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of lactation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of lactation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of lactation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of lactation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1903489") +AnnotationAssertion(rdfs:label "positive regulation of lactation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (liposaccharide metabolic process) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:dph") Annotation( "GO_REF:0000068") Annotation( "PMID:9452964") "The chemical reactions and pathways involving liposaccharide.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2014-10-01T21:52:52Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "liposaccharide metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1903509") +AnnotationAssertion(rdfs:label "liposaccharide metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (mucopolysaccharide metabolic process) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:dph") Annotation( "GO_REF:0000068") Annotation( "PMID:4236091") "The chemical reactions and pathways involving mucopolysaccharide.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2014-10-01T21:55:47Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "mucopolysaccharide metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1903510") +AnnotationAssertion(rdfs:label "mucopolysaccharide metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (regulation of blood circulation) AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mr") Annotation( "GO_REF:0000058") Annotation( "PMID:10659969") "Any process that modulates the frequency, rate or extent of blood circulation.") @@ -45762,8 +124366,51 @@ AnnotationAssertion( "GOC:TermGenie") "regulation of hemolymph circulation") AnnotationAssertion( "GO:1903522") AnnotationAssertion(rdfs:label "regulation of blood circulation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (negative regulation of blood circulation) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mr") Annotation( "GO_REF:0000058") Annotation( "PMID:10659969") "Any process that stops, prevents or reduces the frequency, rate or extent of blood circulation.") +AnnotationAssertion( "mr") +AnnotationAssertion( "2014-10-06T18:39:05Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of blood circulation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of blood circulation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of blood circulation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of blood circulation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down regulation of hemolymph circulation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "down-regulation of hemolymph circulation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "downregulation of hemolymph circulation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "inhibition of hemolymph circulation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "negative regulation of hemolymph circulation") +AnnotationAssertion( "GO:1903523") +AnnotationAssertion(rdfs:label "negative regulation of blood circulation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of blood circulation) + +AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:mr") Annotation( "GO_REF:0000058") Annotation( "PMID:10659969") "Any process that activates or increases the frequency, rate or extent of blood circulation.") +AnnotationAssertion( "mr") +AnnotationAssertion( "2014-10-06T18:39:13Z") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of blood circulation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of blood circulation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of blood circulation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of blood circulation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:TermGenie") "activation of hemolymph circulation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "positive regulation of hemolymph circulation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up regulation of hemolymph circulation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "up-regulation of hemolymph circulation") +AnnotationAssertion(Annotation( "GOC:TermGenie") "upregulation of hemolymph circulation") +AnnotationAssertion( "GO:1903524") +AnnotationAssertion(rdfs:label "positive regulation of blood circulation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + # Class: (regulation of secretion by cell) AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GOC:pm") Annotation( "GO_REF:0000058") Annotation( "PMID:12130530") "Any process that modulates the frequency, rate or extent of secretion by cell.") @@ -45773,6 +124420,7 @@ AnnotationAssertion(Annotation( "biological_process") AnnotationAssertion( "GO:1903530") AnnotationAssertion(rdfs:label "regulation of secretion by cell") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) @@ -54338,18 +132986,6 @@ AnnotationAssertion(rdfs:label "posi EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) -# Class: (pharyngeal gland morphogenesis) - -AnnotationAssertion(Annotation( "GOC:TermGenie") Annotation( "GO_REF:0000083") Annotation( "PMID:21868609") "The developmental process by which a pharyngeal gland is generated and organized.") -AnnotationAssertion( "rz") -AnnotationAssertion( "2017-02-03T14:39:10Z") -AnnotationAssertion(Annotation( "GOC:TermGenie") "pharynx gland morphogenesis") -AnnotationAssertion( "biological_process") -AnnotationAssertion(Annotation( "GOC:TermGenie") "glandulae pharyngeae morphogenesis") -AnnotationAssertion( "GO:1905905") -AnnotationAssertion(rdfs:label "pharyngeal gland morphogenesis") -EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) - # Class: (regulation of calcium ion export across plasma membrane) AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:BHF_miRNA") Annotation( "GOC:TermGenie") Annotation( "GOC:rph") Annotation( "GO_REF:0000058") Annotation( "PMID:22362515") "Any process that modulates the frequency, rate or extent of calcium ion export across the plasma membrane.") @@ -55130,6 +133766,175 @@ AnnotationAssertion( "adaptive thermogenesis") SubClassOf( ) +# Class: (vacuolar localization) + +AnnotationAssertion(Annotation( "PMID:26283797") "Any process in which the vacuole is transported to, and/or maintained in, a specific location within the cell.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/22182"^^xsd:anyURI) +AnnotationAssertion( "mcc") +AnnotationAssertion( "2015-09-10T08:16:02Z") +AnnotationAssertion( "maintenance of vacuolar localization") +AnnotationAssertion( "maintenance of vacuole localization") +AnnotationAssertion( "maintenance of vacuole location") +AnnotationAssertion( "maintenance of vacuolar location") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1990849") +AnnotationAssertion(rdfs:label "vacuolar localization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (acinar cell proliferation) + +AnnotationAssertion(Annotation( "PMID:9788538") "The multiplication or reproduction of acinar cells, resulting in the expansion of a cell population. An acinar cell is a secretory cell that is grouped together with other cells of the same type to form grape-shaped clusters known as acini (singular acinus).") +AnnotationAssertion( "sl") +AnnotationAssertion( "2015-09-25T14:26:09Z") +AnnotationAssertion( "acinic cell proliferation") +AnnotationAssertion( "acinous cell proliferation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1990863") +AnnotationAssertion(rdfs:label "acinar cell proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (vascular associated smooth muscle cell proliferation) + +AnnotationAssertion(Annotation( "PMID:23246467") "The multiplication or reproduction of vascular smooth muscle cells, resulting in the expansion of a cell population. A vascular smooth muscle cell is a non-striated, elongated, spindle-shaped cell found lining the blood vessels.") +AnnotationAssertion( "sl") +AnnotationAssertion( "2015-09-29T16:34:59Z") +AnnotationAssertion( "VSMC proliferation") +AnnotationAssertion( "vascular smooth muscle cell proliferation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1990874") +AnnotationAssertion(rdfs:label "vascular associated smooth muscle cell proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (ribonucleoprotein complex) + +AnnotationAssertion(Annotation( "GOC:krc") Annotation( "GOC:vesicles") "A macromolecular complex that contains both RNA and protein molecules.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2015-11-19T12:26:37Z") +AnnotationAssertion( "GO:0030529") +AnnotationAssertion( "GO:1990903") +AnnotationAssertion( "Wikipedia:Ribonucleoprotein") +AnnotationAssertion( "RNA-protein complex") +AnnotationAssertion( "RNP") +AnnotationAssertion( "protein-RNA complex") +AnnotationAssertion( "extracellular ribonucleoprotein complex") +AnnotationAssertion( "intracellular ribonucleoprotein complex") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:1990904") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "ribonucleoprotein complex") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (ooplasm) + +AnnotationAssertion(Annotation( "PMID:19022436") "The cytoplasm of an ovum.") +AnnotationAssertion( ) +AnnotationAssertion( "sl") +AnnotationAssertion( "2015-12-10T21:40:16Z") +AnnotationAssertion( "cellular_component") +AnnotationAssertion( "GO:1990917") +AnnotationAssertion(rdfs:label "ooplasm") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( ObjectComplementOf())) +DisjointClasses( ObjectSomeValuesFrom( )) + +# Class: (hepatic stellate cell proliferation) + +AnnotationAssertion(Annotation( "GOC:sl") Annotation( "PMID:15358192") Annotation( "PMID:18466260") "The multiplication or reproduction of hepatic stellate cells, resulting in the expansion of a hepatic stellate cell population. Hepatic stellate cells are found in the perisinusoidal space of the liver, and are capable of multiple roles including storage of retinol, presentation of antigen to T cells (including CD1d-restricted NKT cells), and upon activation, production of extracellular matrix components. This cell type comprises approximately 8-15% of total cells in the liver.") +AnnotationAssertion( "sl") +AnnotationAssertion( "2016-01-13T23:12:57Z") +AnnotationAssertion( "Ito cell proliferation") +AnnotationAssertion( "hepatic perisinusoidal cell proliferation") +AnnotationAssertion( "perisinusoidal cell proliferation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:1990922") +AnnotationAssertion(rdfs:label "hepatic stellate cell proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of metanephric S-shaped body morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") Annotation( "GOC:obol") Annotation( "GOC:yaf") "Any process that modulates the frequency, rate or extent of metanephric S-shaped body morphogenesis.") +AnnotationAssertion( "jl") +AnnotationAssertion( "2010-07-30T02:14:33Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000004") +AnnotationAssertion(rdfs:label "regulation of metanephric S-shaped body morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (negative regulation of metanephric S-shaped body morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") Annotation( "GOC:obol") Annotation( "GOC:yaf") "Any process that stops, prevents, or reduces the frequency, rate or extent of metanephric S-shaped body morphogenesis.") +AnnotationAssertion( "jl") +AnnotationAssertion( "2010-07-30T02:14:37Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000005") +AnnotationAssertion(rdfs:label "negative regulation of metanephric S-shaped body morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of metanephric comma-shaped body morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") Annotation( "GOC:obol") Annotation( "GOC:yaf") "Any process that modulates the frequency, rate or extent of metanephric comma-shaped body morphogenesis.") +AnnotationAssertion( "jl") +AnnotationAssertion( "2010-07-30T02:17:12Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000006") +AnnotationAssertion(rdfs:label "regulation of metanephric comma-shaped body morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (negative regulation of metanephric comma-shaped body morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") Annotation( "GOC:obol") Annotation( "GOC:yaf") "Any process that stops, prevents, or reduces the frequency, rate or extent of metanephric comma-shaped body morphogenesis.") +AnnotationAssertion( "jl") +AnnotationAssertion( "2010-07-30T02:17:17Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000007") +AnnotationAssertion(rdfs:label "negative regulation of metanephric comma-shaped body morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of male gonad development) + +AnnotationAssertion(Annotation( "GOC:obol") Annotation( "GOC:yaf") "Any process that modulates the frequency, rate or extent of male gonad development.") +AnnotationAssertion( "jl") +AnnotationAssertion( "2010-07-15T03:29:05Z") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of testicular development") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of testis development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000018") +AnnotationAssertion(rdfs:label "regulation of male gonad development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of male gonad development) + +AnnotationAssertion(Annotation( "GOC:obol") Annotation( "GOC:yaf") "Any process that stops, prevents, or reduces the frequency, rate or extent of male gonad development.") +AnnotationAssertion( "jl") +AnnotationAssertion( "2010-07-15T03:29:10Z") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of testicular development") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of testis development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000019") +AnnotationAssertion(rdfs:label "negative regulation of male gonad development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of male gonad development) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of male gonad development.") +AnnotationAssertion( "jl") +AnnotationAssertion( "2010-07-15T03:29:13Z") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of testicular development") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of testis development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000020") +AnnotationAssertion(rdfs:label "positive regulation of male gonad development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (regulation of multicellular organismal development) AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of multicellular organismal development.") @@ -55138,9 +133943,88 @@ AnnotationAssertion( AnnotationAssertion( "biological_process") AnnotationAssertion( "GO:2000026") AnnotationAssertion(rdfs:label "regulation of multicellular organismal development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) +# Class: (regulation of animal organ morphogenesis) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of animal organ morphogenesis.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2010-08-05T11:26:27Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of histogenesis and organogenesis") +AnnotationAssertion( "GO:2000027") +AnnotationAssertion(rdfs:label "regulation of animal organ morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of stem cell division) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of stem cell division.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2010-08-05T11:34:53Z") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of stem cell renewal") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000035") +AnnotationAssertion(rdfs:label "regulation of stem cell division") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of stem cell population maintenance) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of stem cell population maintenance.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2010-08-05T11:35:25Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of maintenance of pluripotency") +AnnotationAssertion( "GO:2000036") +AnnotationAssertion(rdfs:label "regulation of stem cell population maintenance") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of ureter smooth muscle cell differentiation) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") Annotation( "GOC:obol") Annotation( "GOC:yaf") "Any process that modulates the frequency, rate or extent of ureter smooth muscle cell differentiation.") +AnnotationAssertion( "jl") +AnnotationAssertion( "2010-08-20T01:44:16Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000061") +AnnotationAssertion(rdfs:label "regulation of ureter smooth muscle cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (negative regulation of ureter smooth muscle cell differentiation) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") Annotation( "GOC:obol") Annotation( "GOC:yaf") "Any process that stops, prevents, or reduces the frequency, rate or extent of ureter smooth muscle cell differentiation.") +AnnotationAssertion( "jl") +AnnotationAssertion( "2010-08-20T01:44:23Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000062") +AnnotationAssertion(rdfs:label "negative regulation of ureter smooth muscle cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (positive regulation of ureter smooth muscle cell differentiation) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") Annotation( "GOC:obol") Annotation( "GOC:yaf") "Any process that activates or increases the frequency, rate or extent of ureter smooth muscle cell differentiation.") +AnnotationAssertion( "jl") +AnnotationAssertion( "2010-08-20T01:44:28Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000063") +AnnotationAssertion(rdfs:label "positive regulation of ureter smooth muscle cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (regulation of defense response to insect) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of defense response to insect.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2010-08-23T09:30:00Z") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of physiological defense response to insect") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000068") +AnnotationAssertion(rdfs:label "regulation of defense response to insect") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (regulation of response to water deprivation) AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of response to water deprivation.") @@ -55153,8 +134037,246 @@ AnnotationAssertion( "GOC:obol") "regulation of drought tolerance") AnnotationAssertion( "GO:2000070") AnnotationAssertion(rdfs:label "regulation of response to water deprivation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (regulation of type B pancreatic cell development) + +AnnotationAssertion(Annotation( "GOC:obol") Annotation( "GOC:yaf") "Any process that modulates the frequency, rate or extent of pancreatic B cell development.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2010-08-27T11:19:37Z") +AnnotationAssertion(Annotation( "GOC:mah") "regulation of pancreatic B cell development") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of pancreatic beta cell development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000074") +AnnotationAssertion(rdfs:label "regulation of type B pancreatic cell development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of type B pancreatic cell development) + +AnnotationAssertion(Annotation( "GOC:obol") Annotation( "GOC:yaf") "Any process that stops, prevents, or reduces the frequency, rate or extent of pancreatic B cell development.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2010-08-27T11:21:17Z") +AnnotationAssertion(Annotation( "GOC:mah") "negative regulation of pancreatic B cell development") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of pancreatic beta cell development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000077") +AnnotationAssertion(rdfs:label "negative regulation of type B pancreatic cell development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (positive regulation of type B pancreatic cell development) + +AnnotationAssertion(Annotation( "GOC:obol") Annotation( "GOC:yaf") "Any process that activates or increases the frequency, rate or extent of pancreatic B cell development.") +AnnotationAssertion( "tb") +AnnotationAssertion( "2010-08-27T11:21:19Z") +AnnotationAssertion(Annotation( "GOC:mah") "positive regulation of pancreatic B cell development") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of pancreatic beta cell development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000078") +AnnotationAssertion(rdfs:label "positive regulation of type B pancreatic cell development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "Any process that modulates the frequency, rate or extent of mesenchymal to epithelial transition involved in mesonephros morphogenesis.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-09-03T06:06:41Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of mesonephric mesenchyme to epithelial transition") +AnnotationAssertion( "GO:2000084") +AnnotationAssertion(rdfs:label "regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "Any process that stops, prevents, or reduces the frequency, rate or extent of mesenchymal to epithelial transition involved in mesonephros morphogenesis.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-09-03T06:08:21Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of mesonephric mesenchyme to epithelial transition") +AnnotationAssertion( "GO:2000085") +AnnotationAssertion(rdfs:label "negative regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "Any process that activates or increases the frequency, rate or extent of mesenchymal to epithelial transition involved in mesonephros morphogenesis.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-09-03T06:08:24Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of mesonephric mesenchyme to epithelial transition") +AnnotationAssertion( "GO:2000086") +AnnotationAssertion(rdfs:label "positive regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of mesonephric glomerulus development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "Any process that modulates the frequency, rate or extent of mesonephric glomerulus development.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-09-03T06:09:19Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000087") +AnnotationAssertion(rdfs:label "regulation of mesonephric glomerulus development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (negative regulation of mesonephric glomerulus development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "Any process that stops, prevents, or reduces the frequency, rate or extent of mesonephric glomerulus development.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-09-03T06:09:22Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000088") +AnnotationAssertion(rdfs:label "negative regulation of mesonephric glomerulus development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of mesonephric glomerulus development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "Any process that activates or increases the frequency, rate or extent of mesonephric glomerulus development.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-09-03T06:09:24Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000089") +AnnotationAssertion(rdfs:label "positive regulation of mesonephric glomerulus development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of mesonephric nephron tubule epithelial cell differentiation) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "Any process that modulates the frequency, rate or extent of mesonephric nephron tubule epithelial cell differentiation.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-09-03T06:12:25Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000093") +AnnotationAssertion(rdfs:label "regulation of mesonephric nephron tubule epithelial cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of mesonephric nephron tubule epithelial cell differentiation) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") "Any process that stops, prevents, or reduces the frequency, rate or extent of mesonephric nephron tubule epithelial cell differentiation.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-09-03T06:12:28Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000094") +AnnotationAssertion(rdfs:label "negative regulation of mesonephric nephron tubule epithelial cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of leukocyte apoptotic process) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mtg_apoptosis") "Any process that modulates the frequency, rate or extent of leukocyte apoptotic process.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-09-15T01:42:05Z") +AnnotationAssertion( "regulation of leukocyte apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000106") +AnnotationAssertion(rdfs:label "regulation of leukocyte apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of leukocyte apoptotic process) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mtg_apoptosis") "Any process that stops, prevents, or reduces the frequency, rate or extent of leukocyte apoptotic process.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-09-15T01:42:09Z") +AnnotationAssertion( "negative regulation of leukocyte apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000107") +AnnotationAssertion(rdfs:label "negative regulation of leukocyte apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of leukocyte apoptotic process) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mtg_apoptosis") "Any process that activates or increases the frequency, rate or extent of leukocyte apoptotic process.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-09-15T01:42:12Z") +AnnotationAssertion( "positive regulation of leukocyte apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000108") +AnnotationAssertion(rdfs:label "positive regulation of leukocyte apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of macrophage apoptotic process) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mtg_apoptosis") "Any process that modulates the frequency, rate or extent of macrophage apoptotic process.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-09-15T01:44:15Z") +AnnotationAssertion( "regulation of macrophage apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:yaf") "regulation of AICD") +AnnotationAssertion(Annotation( "GOC:yaf") "regulation of activation-induced cell death") +AnnotationAssertion( "GO:2000109") +AnnotationAssertion(rdfs:label "regulation of macrophage apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of macrophage apoptotic process) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mtg_apoptosis") "Any process that stops, prevents, or reduces the frequency, rate or extent of macrophage apoptotic process.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-09-15T01:44:18Z") +AnnotationAssertion( "negative regulation of macrophage apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:yaf") "negative regulation of AICD") +AnnotationAssertion(Annotation( "GOC:yaf") "negative regulation of activation-induced cell death") +AnnotationAssertion( "GO:2000110") +AnnotationAssertion(rdfs:label "negative regulation of macrophage apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of macrophage apoptotic process) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mtg_apoptosis") "Any process that activates or increases the frequency, rate or extent of macrophage apoptotic process.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-09-15T01:44:21Z") +AnnotationAssertion( "positive regulation of macrophage apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:yaf") "positive regulation of AICD") +AnnotationAssertion(Annotation( "GOC:yaf") "positive regulation of activation-induced cell death") +AnnotationAssertion( "GO:2000111") +AnnotationAssertion(rdfs:label "positive regulation of macrophage apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of establishment of cell polarity) + +AnnotationAssertion(Annotation( "GOC:dph") "Any process that modulates the frequency, rate or extent of establishment of cell polarity.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-09-16T01:22:36Z") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of cell polarization") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of bud site selection/establishment of cell polarity") +AnnotationAssertion( "GO:2000114") +AnnotationAssertion(rdfs:label "regulation of establishment of cell polarity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of cell proliferation involved in heart morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") "Any process that modulates the frequency, rate or extent of cell proliferation involved in heart morphogenesis.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-09-29T12:43:53Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000136") +AnnotationAssertion(rdfs:label "regulation of cell proliferation involved in heart morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of cell proliferation involved in heart morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") "Any process that stops, prevents, or reduces the frequency, rate or extent of cell proliferation involved in heart morphogenesis.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-09-29T12:43:55Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000137") +AnnotationAssertion(rdfs:label "negative regulation of cell proliferation involved in heart morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of cell proliferation involved in heart morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") "Any process that activates or increases the frequency, rate or extent of cell proliferation involved in heart morphogenesis.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-09-29T12:43:57Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000138") +AnnotationAssertion(rdfs:label "positive regulation of cell proliferation involved in heart morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + # Class: (regulation of cell motility) AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of cell motility.") @@ -55166,8 +134288,23 @@ AnnotationAssertion( "GOC:obol") "regulation of cell movement") AnnotationAssertion( "GO:2000145") AnnotationAssertion(rdfs:label "regulation of cell motility") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (negative regulation of cell motility) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of cell motility.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-10-01T09:41:26Z") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of cell locomotion") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of movement of a cell") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of cell movement") +AnnotationAssertion( "GO:2000146") +AnnotationAssertion(rdfs:label "negative regulation of cell motility") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + # Class: (positive regulation of cell motility) AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of cell motility.") @@ -55179,8 +134316,3182 @@ AnnotationAssertion( "GOC:obol") "positive regulation of cell movement") AnnotationAssertion( "GO:2000147") AnnotationAssertion(rdfs:label "positive regulation of cell motility") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) +# Class: (positive regulation of cilium-dependent cell motility) + +AnnotationAssertion(Annotation( "GOC:cilia") Annotation( "GOC:jl") "Any process that activates or increases the frequency, rate or extent of cilium-dependent cell motility.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-10-04T12:41:05Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "positive regulation of ciliary cell motility") +AnnotationAssertion( "GO:2000155") +AnnotationAssertion(rdfs:label "positive regulation of cilium-dependent cell motility") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of dendrite development) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents, or reduces the frequency, rate or extent of dendrite development.") +AnnotationAssertion( "rl") +AnnotationAssertion( "2010-10-07T10:53:15Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000171") +AnnotationAssertion(rdfs:label "negative regulation of dendrite development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of branching morphogenesis of a nerve) + +AnnotationAssertion(Annotation( "GOC:BHF") "Any process that modulates the frequency, rate or extent of branching morphogenesis of a nerve.") +AnnotationAssertion( "rl") +AnnotationAssertion( "2010-10-07T12:07:54Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000172") +AnnotationAssertion(rdfs:label "regulation of branching morphogenesis of a nerve") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of branching morphogenesis of a nerve) + +AnnotationAssertion(Annotation( "GOC:BHF") "Any process that stops, prevents, or reduces the frequency, rate or extent of branching morphogenesis of a nerve.") +AnnotationAssertion( "rl") +AnnotationAssertion( "2010-10-07T12:07:56Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000173") +AnnotationAssertion(rdfs:label "negative regulation of branching morphogenesis of a nerve") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of pro-T cell differentiation) + +AnnotationAssertion(Annotation( "GOC:BHF") "Any process that modulates the frequency, rate or extent of pro-T cell differentiation.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-10-11T10:24:30Z") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of pro-T lymphocyte differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000174") +AnnotationAssertion(rdfs:label "regulation of pro-T cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (negative regulation of pro-T cell differentiation) + +AnnotationAssertion(Annotation( "GOC:BHF") "Any process that stops, prevents, or reduces the frequency, rate or extent of pro-T cell differentiation.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-10-11T10:24:33Z") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of pro-T lymphocyte differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000175") +AnnotationAssertion(rdfs:label "negative regulation of pro-T cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (positive regulation of pro-T cell differentiation) + +AnnotationAssertion(Annotation( "GOC:BHF") "Any process that activates or increases the frequency, rate or extent of pro-T cell differentiation.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-10-11T10:24:35Z") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of pro-T lymphocyte differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000176") +AnnotationAssertion(rdfs:label "positive regulation of pro-T cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (regulation of neural precursor cell proliferation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:yaf") "Any process that modulates the frequency, rate or extent of neural precursor cell proliferation.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-10-13T12:40:41Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000177") +AnnotationAssertion(rdfs:label "regulation of neural precursor cell proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of neural precursor cell proliferation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:yaf") "Any process that stops, prevents, or reduces the frequency, rate or extent of neural precursor cell proliferation.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-10-13T12:40:43Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000178") +AnnotationAssertion(rdfs:label "negative regulation of neural precursor cell proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of neural precursor cell proliferation) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:yaf") "Any process that activates or increases the frequency, rate or extent of neural precursor cell proliferation.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-10-13T12:40:45Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000179") +AnnotationAssertion(rdfs:label "positive regulation of neural precursor cell proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of blood vessel morphogenesis) + +AnnotationAssertion(Annotation( "GOC:dph") Annotation( "GOC:yaf") "Any process that stops, prevents, or reduces the frequency, rate or extent of blood vessel morphogenesis.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-10-13T12:46:31Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000181") +AnnotationAssertion(rdfs:label "negative regulation of blood vessel morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of progesterone biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:dph") "Any process that modulates the frequency, rate or extent of progesterone biosynthetic process.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-10-14T07:36:06Z") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of progesterone anabolism") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of progesterone biosynthesis") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of progesterone formation") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of progesterone synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000182") +AnnotationAssertion(rdfs:label "regulation of progesterone biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of progesterone biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:dph") "Any process that stops, prevents, or reduces the frequency, rate or extent of progesterone biosynthetic process.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-10-14T07:36:10Z") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of progesterone anabolism") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of progesterone biosynthesis") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of progesterone formation") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of progesterone synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000183") +AnnotationAssertion(rdfs:label "negative regulation of progesterone biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of progesterone biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:dph") "Any process that activates or increases the frequency, rate or extent of progesterone biosynthetic process.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-10-14T07:36:14Z") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of progesterone anabolism") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of progesterone biosynthesis") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of progesterone formation") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of progesterone synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000184") +AnnotationAssertion(rdfs:label "positive regulation of progesterone biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of phosphate transmembrane transport) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of phosphate transmembrane transport.") +AnnotationAssertion( "vw") +AnnotationAssertion( "2010-10-15T11:33:04Z") +AnnotationAssertion( "regulation of phosphate membrane transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000185") +AnnotationAssertion(rdfs:label "regulation of phosphate transmembrane transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of phosphate transmembrane transport) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents, or reduces the frequency, rate or extent of phosphate transmembrane transport.") +AnnotationAssertion( "vw") +AnnotationAssertion( "2010-10-15T11:33:08Z") +AnnotationAssertion( "negative regulation of phosphate membrane transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000186") +AnnotationAssertion(rdfs:label "negative regulation of phosphate transmembrane transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of phosphate transmembrane transport) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of phosphate transmembrane transport.") +AnnotationAssertion( "vw") +AnnotationAssertion( "2010-10-15T11:33:10Z") +AnnotationAssertion( "positive regulation of phosphate membrane transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000187") +AnnotationAssertion(rdfs:label "positive regulation of phosphate transmembrane transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of fatty acid transport) + +AnnotationAssertion(Annotation( "GOC:BHF") "Any process that modulates the frequency, rate or extent of fatty acid transport.") +AnnotationAssertion( "rl") +AnnotationAssertion( "2010-10-18T10:37:13Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000191") +AnnotationAssertion(rdfs:label "regulation of fatty acid transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of fatty acid transport) + +AnnotationAssertion(Annotation( "GOC:BHF") "Any process that stops, prevents, or reduces the frequency, rate or extent of fatty acid transport.") +AnnotationAssertion( "rl") +AnnotationAssertion( "2010-10-18T10:37:15Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000192") +AnnotationAssertion(rdfs:label "negative regulation of fatty acid transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of fatty acid transport) + +AnnotationAssertion(Annotation( "GOC:BHF") "Any process that activates or increases the frequency, rate or extent of fatty acid transport.") +AnnotationAssertion( "rl") +AnnotationAssertion( "2010-10-18T10:37:17Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000193") +AnnotationAssertion(rdfs:label "positive regulation of fatty acid transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of female gonad development) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of female gonad development.") +AnnotationAssertion( "yaf") +AnnotationAssertion( "2010-10-19T10:45:34Z") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of ovarian development") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of ovary development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000194") +AnnotationAssertion(rdfs:label "regulation of female gonad development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of female gonad development) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents, or reduces the frequency, rate or extent of female gonad development.") +AnnotationAssertion( "yaf") +AnnotationAssertion( "2010-10-19T10:45:38Z") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of ovarian development") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of ovary development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000195") +AnnotationAssertion(rdfs:label "negative regulation of female gonad development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of female gonad development) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of female gonad development.") +AnnotationAssertion( "yaf") +AnnotationAssertion( "2010-10-19T10:45:41Z") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of ovarian development") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of ovary development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000196") +AnnotationAssertion(rdfs:label "positive regulation of female gonad development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of glutamate metabolic process) + +AnnotationAssertion(Annotation( "GOC:sl") "Any process that modulates the frequency, rate or extent of glutamate metabolic process.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-11-03T02:43:51Z") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of glutamate metabolism") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of glutamic acid metabolic process") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of glutamic acid metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000211") +AnnotationAssertion(rdfs:label "regulation of glutamate metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (negative regulation of glutamate metabolic process) + +AnnotationAssertion(Annotation( "GOC:sl") "Any process that stops, prevents, or reduces the frequency, rate or extent of glutamate metabolic process.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-11-03T02:43:55Z") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of glutamate metabolism") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of glutamic acid metabolic process") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of glutamic acid metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000212") +AnnotationAssertion(rdfs:label "negative regulation of glutamate metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of glutamate metabolic process) + +AnnotationAssertion(Annotation( "GOC:sl") "Any process that activates or increases the frequency, rate or extent of glutamate metabolic process.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-11-03T02:43:59Z") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of glutamate metabolism") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of glutamic acid metabolic process") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of glutamic acid metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000213") +AnnotationAssertion(rdfs:label "positive regulation of glutamate metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of testosterone biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:obol") Annotation( "GOC:yaf") "Any process that modulates the frequency, rate or extent of testosterone biosynthetic process.") +AnnotationAssertion( "yaf") +AnnotationAssertion( "2010-11-09T10:38:33Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000224") +AnnotationAssertion(rdfs:label "regulation of testosterone biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of testosterone biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:obol") Annotation( "GOC:yaf") "Any process that stops, prevents, or reduces the frequency, rate or extent of testosterone biosynthetic process.") +AnnotationAssertion( "yaf") +AnnotationAssertion( "2010-11-09T10:38:37Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000225") +AnnotationAssertion(rdfs:label "negative regulation of testosterone biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of pancreatic A cell differentiation) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of pancreatic A cell differentiation.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-11-09T03:43:37Z") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of pancreatic alpha cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000226") +AnnotationAssertion(rdfs:label "regulation of pancreatic A cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of pancreatic A cell differentiation) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of pancreatic A cell differentiation.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-11-09T03:43:40Z") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of pancreatic alpha cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000227") +AnnotationAssertion(rdfs:label "negative regulation of pancreatic A cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (positive regulation of pancreatic A cell differentiation) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of pancreatic A cell differentiation.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-11-09T03:43:42Z") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of pancreatic alpha cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000228") +AnnotationAssertion(rdfs:label "positive regulation of pancreatic A cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (regulation of reproductive process) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of reproductive process.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-11-10T02:44:02Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000241") +AnnotationAssertion(rdfs:label "regulation of reproductive process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (negative regulation of reproductive process) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents, or reduces the frequency, rate or extent of reproductive process.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-11-10T02:44:05Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000242") +AnnotationAssertion(rdfs:label "negative regulation of reproductive process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of reproductive process) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of reproductive process.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-11-10T02:44:08Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000243") +AnnotationAssertion(rdfs:label "positive regulation of reproductive process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of establishment or maintenance of neuroblast polarity) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents, or reduces the frequency, rate or extent of establishment or maintenance of neuroblast polarity.") +AnnotationAssertion( "vw") +AnnotationAssertion( "2010-11-11T11:40:34Z") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of establishment and/or maintenance of neuroblast cell polarity") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000248") +AnnotationAssertion(rdfs:label "negative regulation of establishment or maintenance of neuroblast polarity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (negative regulation of feeding behavior) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of feeding behavior.") +AnnotationAssertion( "yaf") +AnnotationAssertion( "2010-11-18T11:24:14Z") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of behavioral response to food") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of behavioural response to food") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of feeding behaviour") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of drinking") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of eating") +AnnotationAssertion( "GO:2000252") +AnnotationAssertion(rdfs:label "negative regulation of feeding behavior") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of feeding behavior) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of feeding behavior.") +AnnotationAssertion( "yaf") +AnnotationAssertion( "2010-11-18T11:24:18Z") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of behavioral response to food") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of behavioural response to food") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of feeding behaviour") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of drinking") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of eating") +AnnotationAssertion( "GO:2000253") +AnnotationAssertion(rdfs:label "positive regulation of feeding behavior") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of male germ cell proliferation) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of male germ cell proliferation.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-11-18T09:29:44Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000254") +AnnotationAssertion(rdfs:label "regulation of male germ cell proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of male germ cell proliferation) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of male germ cell proliferation.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-11-18T09:29:47Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000255") +AnnotationAssertion(rdfs:label "negative regulation of male germ cell proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (positive regulation of male germ cell proliferation) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of male germ cell proliferation.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2010-11-18T09:29:50Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000256") +AnnotationAssertion(rdfs:label "positive regulation of male germ cell proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of fibroblast apoptotic process) + +AnnotationAssertion(Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:obol") Annotation( "GOC:yaf") "Any process that modulates the frequency, rate or extent of fibroblast apoptotic process.") +AnnotationAssertion( "jl") +AnnotationAssertion( "2010-11-23T01:07:23Z") +AnnotationAssertion( "regulation of fibroblast apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000269") +AnnotationAssertion(rdfs:label "regulation of fibroblast apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of fibroblast apoptotic process) + +AnnotationAssertion(Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:obol") Annotation( "GOC:yaf") "Any process that stops, prevents or reduces the frequency, rate or extent of fibroblast apoptotic process.") +AnnotationAssertion( "jl") +AnnotationAssertion( "2010-11-23T01:07:27Z") +AnnotationAssertion( "negative regulation of fibroblast apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000270") +AnnotationAssertion(rdfs:label "negative regulation of fibroblast apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of fibroblast apoptotic process) + +AnnotationAssertion(Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:obol") Annotation( "GOC:yaf") "Any process that activates or increases the frequency, rate or extent of fibroblast apoptotic process.") +AnnotationAssertion( "jl") +AnnotationAssertion( "2010-11-23T01:07:29Z") +AnnotationAssertion( "positive regulation of fibroblast apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000271") +AnnotationAssertion(rdfs:label "positive regulation of fibroblast apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of signaling receptor activity) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of a signaling receptor activity.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2010-12-02T09:28:47Z") +AnnotationAssertion( "negative regulation of receptor activity") +AnnotationAssertion( "negative regulation of signalling receptor activity") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000272") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "negative regulation of signaling receptor activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of signaling receptor activity) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of signaling receptor activity.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2010-12-02T09:28:50Z") +AnnotationAssertion( "positive regulation of signalling receptor activity") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000273") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "positive regulation of signaling receptor activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of DNA biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of DNA biosynthetic process.") +AnnotationAssertion( "yaf") +AnnotationAssertion( "2010-12-08T04:48:15Z") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of DNA anabolism") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of DNA biosynthesis") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of DNA formation") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of DNA synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000278") +AnnotationAssertion(rdfs:label "regulation of DNA biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of DNA biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of DNA biosynthetic process.") +AnnotationAssertion( "yaf") +AnnotationAssertion( "2010-12-08T04:48:20Z") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of DNA anabolism") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of DNA biosynthesis") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of DNA formation") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of DNA synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000279") +AnnotationAssertion(rdfs:label "negative regulation of DNA biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of cellular amino acid biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of cellular amino acid biosynthetic process.") +AnnotationAssertion( "vw") +AnnotationAssertion( "2010-12-10T11:54:19Z") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of amino acid biosynthetic process") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of cellular amino acid anabolism") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of cellular amino acid biosynthesis") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of cellular amino acid formation") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of cellular amino acid synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000282") +AnnotationAssertion(rdfs:label "regulation of cellular amino acid biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of amino acid biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of an amino acid biosynthetic process.") +AnnotationAssertion( "vw") +AnnotationAssertion( "2010-12-10T11:54:23Z") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of amino acid anabolism") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of amino acid biosynthesis") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of amino acid formation") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of amino acid synthesis") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of cellular amino acid biosynthetic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000283") +AnnotationAssertion(rdfs:label "negative regulation of amino acid biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of amino acid biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of cellular amino acid biosynthetic process.") +AnnotationAssertion( "vw") +AnnotationAssertion( "2010-12-10T11:54:27Z") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of amino acid anabolism") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of amino acid biosynthesis") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of amino acid formation") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of amino acid synthesis") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of cellular amino acid biosynthetic process") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000284") +AnnotationAssertion(rdfs:label "positive regulation of amino acid biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of myotome development) + +AnnotationAssertion(Annotation( "GOC:BHF") "Any process that activates or increases the frequency, rate or extent of myotome development.") +AnnotationAssertion( "rl") +AnnotationAssertion( "2010-12-16T05:17:15Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000287") +AnnotationAssertion(rdfs:label "positive regulation of myotome development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of myoblast proliferation) + +AnnotationAssertion(Annotation( "GOC:BHF") "Any process that activates or increases the frequency, rate or extent of myoblast proliferation.") +AnnotationAssertion( "rl") +AnnotationAssertion( "2010-12-16T05:20:52Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000288") +AnnotationAssertion(rdfs:label "positive regulation of myoblast proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of myotome development) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of myotome development.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-12-20T10:22:05Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000290") +AnnotationAssertion(rdfs:label "regulation of myotome development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of myoblast proliferation) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of myoblast proliferation.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2010-12-20T10:34:26Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000291") +AnnotationAssertion(rdfs:label "regulation of myoblast proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of defecation) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of defecation.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2010-12-21T09:23:08Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000292") +AnnotationAssertion(rdfs:label "regulation of defecation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (negative regulation of defecation) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of defecation.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2010-12-21T09:23:13Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000293") +AnnotationAssertion(rdfs:label "negative regulation of defecation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of defecation) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of defecation.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2010-12-21T09:23:16Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000294") +AnnotationAssertion(rdfs:label "positive regulation of defecation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of synaptic vesicle exocytosis) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of synaptic vesicle exocytosis.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2011-01-03T08:20:40Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000300") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "regulation of synaptic vesicle exocytosis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (negative regulation of synaptic vesicle exocytosis) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle exocytosis.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2011-01-03T08:21:00Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000301") +AnnotationAssertion(rdfs:label "negative regulation of synaptic vesicle exocytosis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of synaptic vesicle exocytosis) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of synaptic vesicle exocytosis.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2011-01-03T08:21:14Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000302") +AnnotationAssertion(rdfs:label "positive regulation of synaptic vesicle exocytosis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (regulation of ceramide biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:dph") "Any process that modulates the frequency, rate or extent of a ceramide biosynthetic process.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2011-01-04T02:37:12Z") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of ceramide anabolism") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of ceramide biosynthesis") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of ceramide formation") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of ceramide synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000303") +AnnotationAssertion(rdfs:label "regulation of ceramide biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of ceramide biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:dph") "Any process that activates or increases the frequency, rate or extent of ceramide biosynthetic process.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2011-01-04T02:37:32Z") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of ceramide anabolism") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of ceramide biosynthesis") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of ceramide formation") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of ceramide synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000304") +AnnotationAssertion(rdfs:label "positive regulation of ceramide biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of glucocorticoid receptor signaling pathway) + +AnnotationAssertion(Annotation( "GOC:BHF") "Any process that modulates the frequency, rate or extent of glucocorticoid receptor signaling pathway.") +AnnotationAssertion( "vk") +AnnotationAssertion( "2011-01-18T04:38:10Z") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of glucocorticoid receptor signalling pathway") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000322") +AnnotationAssertion(rdfs:label "regulation of glucocorticoid receptor signaling pathway") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of glucocorticoid receptor signaling pathway) + +AnnotationAssertion(Annotation( "GOC:BHF") "Any process that stops, prevents or reduces the frequency, rate or extent of glucocorticoid receptor signaling pathway.") +AnnotationAssertion( "vk") +AnnotationAssertion( "2011-01-18T04:38:43Z") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of glucocorticoid receptor signalling pathway") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000323") +AnnotationAssertion(rdfs:label "negative regulation of glucocorticoid receptor signaling pathway") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of glucocorticoid receptor signaling pathway) + +AnnotationAssertion(Annotation( "GOC:BHF") "Any process that activates or increases the frequency, rate or extent of glucocorticoid receptor signaling pathway.") +AnnotationAssertion( "vk") +AnnotationAssertion( "2011-01-18T04:39:05Z") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of glucocorticoid receptor signalling pathway") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000324") +AnnotationAssertion(rdfs:label "positive regulation of glucocorticoid receptor signaling pathway") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of endothelial cell apoptotic process) + +AnnotationAssertion(Annotation( "GOC:mah") Annotation( "GOC:mtg_apoptosis") "Any process that modulates the frequency, rate or extent of endothelial cell apoptotic process.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2011-02-03T10:43:16Z") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of apoptosis of endothelial cells") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of endothelial cell programmed cell death by apoptosis") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of killing of endothelial cells") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of programmed cell death of endothelial cells by apoptosis") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of programmed cell death, endothelial cells") +AnnotationAssertion( "regulation of endothelial cell apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000351") +AnnotationAssertion(rdfs:label "regulation of endothelial cell apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of endothelial cell apoptotic process) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mah") Annotation( "GOC:mtg_apoptosis") "Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell apoptotic process.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2011-02-03T10:43:20Z") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of apoptosis of endothelial cells") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of endothelial cell programmed cell death by apoptosis") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of killing of endothelial cells") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of programmed cell death of endothelial cells by apoptosis") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of programmed cell death, endothelial cells") +AnnotationAssertion( "negative regulation of endothelial cell apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000352") +AnnotationAssertion(rdfs:label "negative regulation of endothelial cell apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of endothelial cell apoptotic process) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:mah") Annotation( "GOC:mtg_apoptosis") "Any process that activates or increases the frequency, rate or extent of endothelial cell apoptotic process.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2011-02-03T10:43:23Z") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of apoptosis of endothelial cells") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of endothelial cell programmed cell death by apoptosis") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of killing of endothelial cells") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of programmed cell death of endothelial cells by apoptosis") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of programmed cell death, endothelial cells") +AnnotationAssertion( "positive regulation of endothelial cell apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000353") +AnnotationAssertion(rdfs:label "positive regulation of endothelial cell apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of ovarian follicle development) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of ovarian follicle development.") +AnnotationAssertion( "yaf") +AnnotationAssertion( "2011-02-03T02:01:28Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of follicular phase") +AnnotationAssertion( "GO:2000354") +AnnotationAssertion(rdfs:label "regulation of ovarian follicle development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of ovarian follicle development) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of ovarian follicle development.") +AnnotationAssertion( "yaf") +AnnotationAssertion( "2011-02-03T02:01:32Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of follicular phase") +AnnotationAssertion( "GO:2000355") +AnnotationAssertion(rdfs:label "negative regulation of ovarian follicle development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of oxygen metabolic process) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of oxygen metabolic process.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2011-02-11T02:03:32Z") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of diatomic oxygen metabolic process") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of oxygen metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000374") +AnnotationAssertion(rdfs:label "regulation of oxygen metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of oxygen metabolic process) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents or reduces the frequency, rate or extent of oxygen metabolic process.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2011-02-11T02:03:44Z") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of diatomic oxygen metabolic process") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of oxygen metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000375") +AnnotationAssertion(rdfs:label "negative regulation of oxygen metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of oxygen metabolic process) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of oxygen metabolic process.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2011-02-11T02:03:52Z") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of diatomic oxygen metabolic process") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of oxygen metabolism") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000376") +AnnotationAssertion(rdfs:label "positive regulation of oxygen metabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of mesoderm development) + +AnnotationAssertion(Annotation( "GOC:BHF") "Any process that modulates the frequency, rate or extent of mesoderm development.") +AnnotationAssertion( "vk") +AnnotationAssertion( "2011-02-15T03:09:46Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000380") +AnnotationAssertion(rdfs:label "regulation of mesoderm development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (negative regulation of mesoderm development) + +AnnotationAssertion(Annotation( "GOC:BHF") "Any process that stops, prevents or reduces the frequency, rate or extent of mesoderm development.") +AnnotationAssertion( "vk") +AnnotationAssertion( "2011-02-15T03:10:02Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000381") +AnnotationAssertion(rdfs:label "negative regulation of mesoderm development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of mesoderm development) + +AnnotationAssertion(Annotation( "GOC:BHF") "Any process that activates or increases the frequency, rate or extent of mesoderm development.") +AnnotationAssertion( "vk") +AnnotationAssertion( "2011-02-15T03:10:12Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000382") +AnnotationAssertion(rdfs:label "positive regulation of mesoderm development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of ectoderm development) + +AnnotationAssertion(Annotation( "GOC:BHF") "Any process that modulates the frequency, rate or extent of ectoderm development.") +AnnotationAssertion( "vk") +AnnotationAssertion( "2011-02-15T03:17:10Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000383") +AnnotationAssertion(rdfs:label "regulation of ectoderm development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (negative regulation of ectoderm development) + +AnnotationAssertion(Annotation( "GOC:BHF") "Any process that stops, prevents or reduces the frequency, rate or extent of ectoderm development.") +AnnotationAssertion( "vk") +AnnotationAssertion( "2011-02-15T03:17:27Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000384") +AnnotationAssertion(rdfs:label "negative regulation of ectoderm development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of ectoderm development) + +AnnotationAssertion(Annotation( "GOC:BHF") "Any process that activates or increases the frequency, rate or extent of ectoderm development.") +AnnotationAssertion( "vk") +AnnotationAssertion( "2011-02-15T03:17:39Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000385") +AnnotationAssertion(rdfs:label "positive regulation of ectoderm development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of ovarian follicle development) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of ovarian follicle development.") +AnnotationAssertion( "yaf") +AnnotationAssertion( "2011-02-16T02:21:21Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of follicular phase") +AnnotationAssertion( "GO:2000386") +AnnotationAssertion(rdfs:label "positive regulation of ovarian follicle development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of antral ovarian follicle growth) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of antral ovarian follicle growth.") +AnnotationAssertion( "yaf") +AnnotationAssertion( "2011-02-16T04:53:43Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000387") +AnnotationAssertion(rdfs:label "regulation of antral ovarian follicle growth") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of antral ovarian follicle growth) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of antral ovarian follicle growth.") +AnnotationAssertion( "yaf") +AnnotationAssertion( "2011-02-16T04:54:01Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000388") +AnnotationAssertion(rdfs:label "positive regulation of antral ovarian follicle growth") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of lymphocyte migration) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of lymphocyte migration.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2011-02-23T10:45:19Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000401") +AnnotationAssertion(rdfs:label "regulation of lymphocyte migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of lymphocyte migration) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents or reduces the frequency, rate or extent of lymphocyte migration.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2011-02-23T10:45:47Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000402") +AnnotationAssertion(rdfs:label "negative regulation of lymphocyte migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of lymphocyte migration) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of lymphocyte migration.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2011-02-23T10:46:06Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000403") +AnnotationAssertion(rdfs:label "positive regulation of lymphocyte migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of T cell migration) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of T cell migration.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2011-02-23T10:48:24Z") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of T lymphocyte migration") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of T-cell migration") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of T-lymphocyte migration") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000404") +AnnotationAssertion(rdfs:label "regulation of T cell migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of T cell migration) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents or reduces the frequency, rate or extent of T cell migration.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2011-02-23T10:48:52Z") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of T lymphocyte migration") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of T-cell migration") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of T-lymphocyte migration") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000405") +AnnotationAssertion(rdfs:label "negative regulation of T cell migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of T cell migration) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of T cell migration.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2011-02-23T10:49:12Z") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of T lymphocyte migration") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of T-cell migration") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of T-lymphocyte migration") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000406") +AnnotationAssertion(rdfs:label "positive regulation of T cell migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of thymocyte migration) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that modulates the frequency, rate or extent of thymocyte migration.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2011-02-23T01:33:32Z") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of thymic lymphocyte migration") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of immature T cell migration") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of immature T lymphocyte migration") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of immature T-cell migration") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of immature T-lymphocyte migration") +AnnotationAssertion( "GO:2000410") +AnnotationAssertion(rdfs:label "regulation of thymocyte migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of thymocyte migration) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that stops, prevents or reduces the frequency, rate or extent of thymocyte migration.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2011-02-23T01:34:01Z") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of thymic lymphocyte migration") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of immature T cell migration") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of immature T lymphocyte migration") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of immature T-cell migration") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of immature T-lymphocyte migration") +AnnotationAssertion( "GO:2000411") +AnnotationAssertion(rdfs:label "negative regulation of thymocyte migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of thymocyte migration) + +AnnotationAssertion(Annotation( "GOC:mah") "Any process that activates or increases the frequency, rate or extent of thymocyte migration.") +AnnotationAssertion( "mah") +AnnotationAssertion( "2011-02-23T01:34:23Z") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of thymic lymphocyte migration") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of immature T cell migration") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of immature T lymphocyte migration") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of immature T-cell migration") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of immature T-lymphocyte migration") +AnnotationAssertion( "GO:2000412") +AnnotationAssertion(rdfs:label "positive regulation of thymocyte migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of astrocyte chemotaxis) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of astrocyte chemotaxis.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-03-04T10:53:50Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000458") +AnnotationAssertion(rdfs:label "regulation of astrocyte chemotaxis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of astrocyte chemotaxis) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of astrocyte chemotaxis.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-03-04T10:54:28Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000459") +AnnotationAssertion(rdfs:label "negative regulation of astrocyte chemotaxis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of excitatory postsynaptic potential) + +AnnotationAssertion(Annotation( "GOC:BHF") Annotation( "GOC:bf") "Any process that enhances the establishment or increases the extent of the excitatory postsynaptic potential (EPSP) which is a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential.") +AnnotationAssertion( "rl") +AnnotationAssertion( "2011-03-04T02:43:32Z") +AnnotationAssertion( "positive regulation of excitatory post-synaptic membrane potential") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:bf") Annotation( "GOC:obol") "positive regulation of EPSP") +AnnotationAssertion( "GO:2000463") +AnnotationAssertion(rdfs:label "positive regulation of excitatory postsynaptic potential") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (positive regulation of astrocyte chemotaxis) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of astrocyte chemotaxis.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-03-04T04:43:29Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000464") +AnnotationAssertion(rdfs:label "positive regulation of astrocyte chemotaxis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of hematopoietic stem cell migration) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of hematopoietic stem cell migration.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-03-09T09:34:08Z") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of hemopoietic stem cell migration") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000471") +AnnotationAssertion(rdfs:label "regulation of hematopoietic stem cell migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of hematopoietic stem cell migration) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic stem cell migration.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-03-09T09:34:54Z") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of hemopoietic stem cell migration") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000472") +AnnotationAssertion(rdfs:label "negative regulation of hematopoietic stem cell migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of hematopoietic stem cell migration) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of hematopoietic stem cell migration.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-03-09T09:35:25Z") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of hemopoietic stem cell migration") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000473") +AnnotationAssertion(rdfs:label "positive regulation of hematopoietic stem cell migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of metanephric podocyte development) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of metanephric glomerular visceral epithelial cell development.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/23000"^^xsd:anyURI) +AnnotationAssertion( "yaf") +AnnotationAssertion( "2011-03-09T05:16:40Z") +AnnotationAssertion( "regulation of metanephric glomerular visceral epithelial cell development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000477") +AnnotationAssertion(rdfs:label "regulation of metanephric podocyte development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of metanephric podocyte development) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of metanephric glomerular visceral epithelial cell development.") +AnnotationAssertion( "https://github.com/geneontology/go-ontology/issues/23000"^^xsd:anyURI) +AnnotationAssertion( "yaf") +AnnotationAssertion( "2011-03-09T05:17:26Z") +AnnotationAssertion( "positive regulation of metanephric glomerular visceral epithelial cell development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000478") +AnnotationAssertion(rdfs:label "positive regulation of metanephric podocyte development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of hepatic stellate cell activation) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of hepatic stellate cell activation.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-03-14T03:48:32Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000489") +AnnotationAssertion(rdfs:label "regulation of hepatic stellate cell activation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of hepatic stellate cell activation) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of hepatic stellate cell activation.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-03-14T03:49:18Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000490") +AnnotationAssertion(rdfs:label "negative regulation of hepatic stellate cell activation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of hepatic stellate cell activation) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of hepatic stellate cell activation.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-03-14T03:49:48Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000491") +AnnotationAssertion(rdfs:label "positive regulation of hepatic stellate cell activation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of cell proliferation involved in compound eye morphogenesis) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of cell proliferation involved in compound eye morphogenesis.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-03-18T02:18:34Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000495") +AnnotationAssertion(rdfs:label "regulation of cell proliferation involved in compound eye morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of cell proliferation involved in compound eye morphogenesis) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation involved in compound eye morphogenesis.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-03-18T02:19:22Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000496") +AnnotationAssertion(rdfs:label "negative regulation of cell proliferation involved in compound eye morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of cell proliferation involved in compound eye morphogenesis) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of cell proliferation involved in compound eye morphogenesis.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-03-18T02:19:54Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000497") +AnnotationAssertion(rdfs:label "positive regulation of cell proliferation involved in compound eye morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of dendritic cell chemotaxis) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of dendritic cell chemotaxis.") +AnnotationAssertion( "ebc") +AnnotationAssertion( "2011-03-22T10:21:38Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000508") +AnnotationAssertion(rdfs:label "regulation of dendritic cell chemotaxis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of dendritic cell chemotaxis) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell chemotaxis.") +AnnotationAssertion( "ebc") +AnnotationAssertion( "2011-03-22T10:21:45Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000509") +AnnotationAssertion(rdfs:label "negative regulation of dendritic cell chemotaxis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of dendritic cell chemotaxis) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of dendritic cell chemotaxis.") +AnnotationAssertion( "ebc") +AnnotationAssertion( "2011-03-22T10:21:49Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000510") +AnnotationAssertion(rdfs:label "positive regulation of dendritic cell chemotaxis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of myeloid dendritic cell chemotaxis) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of myeloid dendritic cell chemotaxis.") +AnnotationAssertion( "ebc") +AnnotationAssertion( "2011-03-23T12:18:32Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000527") +AnnotationAssertion(rdfs:label "regulation of myeloid dendritic cell chemotaxis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of myeloid dendritic cell chemotaxis) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of myeloid dendritic cell chemotaxis.") +AnnotationAssertion( "ebc") +AnnotationAssertion( "2011-03-23T12:18:39Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000528") +AnnotationAssertion(rdfs:label "negative regulation of myeloid dendritic cell chemotaxis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of myeloid dendritic cell chemotaxis) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of myeloid dendritic cell chemotaxis.") +AnnotationAssertion( "ebc") +AnnotationAssertion( "2011-03-23T12:18:45Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000529") +AnnotationAssertion(rdfs:label "positive regulation of myeloid dendritic cell chemotaxis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of B cell chemotaxis) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of B cell chemotaxis.") +AnnotationAssertion( "ebc") +AnnotationAssertion( "2011-03-29T09:49:25Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000537") +AnnotationAssertion(rdfs:label "regulation of B cell chemotaxis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of B cell chemotaxis) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of B cell chemotaxis.") +AnnotationAssertion( "ebc") +AnnotationAssertion( "2011-03-29T09:49:33Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000538") +AnnotationAssertion(rdfs:label "positive regulation of B cell chemotaxis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of gastrulation) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of gastrulation.") +AnnotationAssertion( "yaf") +AnnotationAssertion( "2011-04-01T04:10:08Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000542") +AnnotationAssertion(rdfs:label "negative regulation of gastrulation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of gastrulation) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of gastrulation.") +AnnotationAssertion( "yaf") +AnnotationAssertion( "2011-04-01T04:10:15Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000543") +AnnotationAssertion(rdfs:label "positive regulation of gastrulation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of dendritic cell dendrite assembly) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of dendritic cell dendrite assembly.") +AnnotationAssertion( "ebc") +AnnotationAssertion( "2011-04-03T07:21:55Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of dendritic extension") +AnnotationAssertion( "GO:2000547") +AnnotationAssertion(rdfs:label "regulation of dendritic cell dendrite assembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of dendritic cell dendrite assembly) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell dendrite assembly.") +AnnotationAssertion( "ebc") +AnnotationAssertion( "2011-04-03T07:22:01Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of dendritic extension") +AnnotationAssertion( "GO:2000548") +AnnotationAssertion(rdfs:label "negative regulation of dendritic cell dendrite assembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of dendritic cell dendrite assembly) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of dendritic cell dendrite assembly.") +AnnotationAssertion( "ebc") +AnnotationAssertion( "2011-04-03T07:22:06Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of dendritic extension") +AnnotationAssertion( "GO:2000549") +AnnotationAssertion(rdfs:label "positive regulation of dendritic cell dendrite assembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of B cell chemotaxis) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of B cell chemotaxis.") +AnnotationAssertion( "ebc") +AnnotationAssertion( "2011-04-03T07:25:59Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000550") +AnnotationAssertion(rdfs:label "negative regulation of B cell chemotaxis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of DNA biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of DNA biosynthetic process.") +AnnotationAssertion( "yaf") +AnnotationAssertion( "2011-04-04T10:01:20Z") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of DNA anabolism") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of DNA biosynthesis") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of DNA formation") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of DNA synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000573") +AnnotationAssertion(rdfs:label "positive regulation of DNA biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of optic nerve formation) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of optic nerve formation.") +AnnotationAssertion( "yaf") +AnnotationAssertion( "2011-04-11T03:41:30Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of CN II biosynthesis") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of CN II formation") +AnnotationAssertion( "GO:2000595") +AnnotationAssertion(rdfs:label "regulation of optic nerve formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (negative regulation of optic nerve formation) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of optic nerve formation.") +AnnotationAssertion( "yaf") +AnnotationAssertion( "2011-04-11T03:41:35Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of CN II biosynthesis") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of CN II formation") +AnnotationAssertion( "GO:2000596") +AnnotationAssertion(rdfs:label "negative regulation of optic nerve formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of optic nerve formation) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of optic nerve formation.") +AnnotationAssertion( "yaf") +AnnotationAssertion( "2011-04-11T03:41:39Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of CN II biosynthesis") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of CN II formation") +AnnotationAssertion( "GO:2000597") +AnnotationAssertion(rdfs:label "positive regulation of optic nerve formation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of cell proliferation involved in mesonephros development) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of cell proliferation involved in mesonephros development.") +AnnotationAssertion( "yaf") +AnnotationAssertion( "2011-04-18T08:42:19Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000606") +AnnotationAssertion(rdfs:label "regulation of cell proliferation involved in mesonephros development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of cell proliferation involved in mesonephros development) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation involved in mesonephros development.") +AnnotationAssertion( "yaf") +AnnotationAssertion( "2011-04-18T08:42:23Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000607") +AnnotationAssertion(rdfs:label "negative regulation of cell proliferation involved in mesonephros development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of cell proliferation involved in mesonephros development) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of cell proliferation involved in mesonephros development.") +AnnotationAssertion( "yaf") +AnnotationAssertion( "2011-04-18T08:42:25Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000608") +AnnotationAssertion(rdfs:label "positive regulation of cell proliferation involved in mesonephros development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of thyroid hormone generation) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of thyroid hormone generation.") +AnnotationAssertion( "yaf") +AnnotationAssertion( "2011-04-18T10:12:14Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000609") +AnnotationAssertion(rdfs:label "regulation of thyroid hormone generation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of thyroid hormone generation) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of thyroid hormone generation.") +AnnotationAssertion( "yaf") +AnnotationAssertion( "2011-04-18T10:12:19Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000610") +AnnotationAssertion(rdfs:label "negative regulation of thyroid hormone generation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of thyroid hormone generation) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of thyroid hormone generation.") +AnnotationAssertion( "yaf") +AnnotationAssertion( "2011-04-18T10:12:22Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000611") +AnnotationAssertion(rdfs:label "positive regulation of thyroid hormone generation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of stem cell proliferation) + +AnnotationAssertion(Annotation( "GOC:dph") "Any process that stops, prevents or reduces the frequency, rate or extent of stem cell proliferation.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2011-04-27T01:04:22Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000647") +AnnotationAssertion(rdfs:label "negative regulation of stem cell proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of stem cell proliferation) + +AnnotationAssertion(Annotation( "GOC:dph") "Any process that activates or increases the frequency, rate or extent of stem cell proliferation.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2011-04-27T01:04:25Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000648") +AnnotationAssertion(rdfs:label "positive regulation of stem cell proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of sodium ion transmembrane transporter activity) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of sodium ion transmembrane transporter activity.") +AnnotationAssertion( "yaf") +AnnotationAssertion( "2011-04-28T08:42:53Z") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of sodium transporter activity") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000649") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "regulation of sodium ion transmembrane transporter activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (negative regulation of sodium ion transmembrane transporter activity) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of sodium ion transmembrane transporter activity.") +AnnotationAssertion( "yaf") +AnnotationAssertion( "2011-04-28T08:42:57Z") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of sodium transporter activity") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000650") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "negative regulation of sodium ion transmembrane transporter activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (positive regulation of sodium ion transmembrane transporter activity) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of sodium ion transmembrane transporter activity.") +AnnotationAssertion( "yaf") +AnnotationAssertion( "2011-04-28T08:43:00Z") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of sodium transporter activity") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000651") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "positive regulation of sodium ion transmembrane transporter activity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (regulation of cellular response to testosterone stimulus) + +AnnotationAssertion(Annotation( "GOC:BHF") "Any process that modulates the frequency, rate or extent of cellular response to testosterone stimulus.") +AnnotationAssertion( "vk") +AnnotationAssertion( "2011-05-02T03:23:56Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000654") +AnnotationAssertion(rdfs:label "regulation of cellular response to testosterone stimulus") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of cellular response to testosterone stimulus) + +AnnotationAssertion(Annotation( "GOC:BHF") "Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to testosterone stimulus.") +AnnotationAssertion( "vk") +AnnotationAssertion( "2011-05-02T03:23:59Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000655") +AnnotationAssertion(rdfs:label "negative regulation of cellular response to testosterone stimulus") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of apolipoprotein binding) + +AnnotationAssertion(Annotation( "GOC:BHF") "Any process that modulates the frequency, rate or extent of apolipoprotein binding.") +AnnotationAssertion( "vk") +AnnotationAssertion( "2011-05-02T05:33:41Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000656") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "regulation of apolipoprotein binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of apolipoprotein binding) + +AnnotationAssertion(Annotation( "GOC:BHF") "Any process that stops, prevents or reduces the frequency, rate or extent of apolipoprotein binding.") +AnnotationAssertion( "vk") +AnnotationAssertion( "2011-05-02T05:33:44Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000657") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "negative regulation of apolipoprotein binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of apolipoprotein binding) + +AnnotationAssertion(Annotation( "GOC:BHF") "Any process that activates or increases the frequency, rate or extent of apolipoprotein binding.") +AnnotationAssertion( "vk") +AnnotationAssertion( "2011-05-02T05:33:46Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000658") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "positive regulation of apolipoprotein binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of dendritic cell apoptotic process) + +AnnotationAssertion(Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of dendritic cell apoptotic process.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2011-05-09T07:34:16Z") +AnnotationAssertion( "regulation of dendritic cell apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000668") +AnnotationAssertion(rdfs:label "regulation of dendritic cell apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of dendritic cell apoptotic process) + +AnnotationAssertion(Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell apoptotic process.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2011-05-09T07:34:21Z") +AnnotationAssertion( "negative regulation of dendritic cell apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000669") +AnnotationAssertion(rdfs:label "negative regulation of dendritic cell apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of dendritic cell apoptotic process) + +AnnotationAssertion(Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of dendritic cell apoptotic process.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2011-05-09T07:34:26Z") +AnnotationAssertion( "positive regulation of dendritic cell apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000670") +AnnotationAssertion(rdfs:label "positive regulation of dendritic cell apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of motor neuron apoptotic process) + +AnnotationAssertion(Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of motor neuron apoptotic process.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2011-05-09T10:56:17Z") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of motoneuron apoptosis") +AnnotationAssertion( "regulation of motor neuron apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000671") +AnnotationAssertion(rdfs:label "regulation of motor neuron apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of motor neuron apoptotic process) + +AnnotationAssertion(Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of motor neuron apoptotic process.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2011-05-09T10:56:21Z") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of motoneuron apoptosis") +AnnotationAssertion( "negative regulation of motor neuron apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000672") +AnnotationAssertion(rdfs:label "negative regulation of motor neuron apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of motor neuron apoptotic process) + +AnnotationAssertion(Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of motor neuron apoptotic process.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2011-05-09T10:56:24Z") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of motoneuron apoptosis") +AnnotationAssertion( "positive regulation of motor neuron apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000673") +AnnotationAssertion(rdfs:label "positive regulation of motor neuron apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of type B pancreatic cell apoptotic process) + +AnnotationAssertion(Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of type B pancreatic cell apoptotic process.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2011-05-09T11:51:09Z") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of pancreatic B cell apoptosis") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of pancreatic beta cell apoptosis") +AnnotationAssertion( "regulation of type B pancreatic cell apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000674") +AnnotationAssertion(rdfs:label "regulation of type B pancreatic cell apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of type B pancreatic cell apoptotic process) + +AnnotationAssertion(Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of type B pancreatic cell apoptotic process.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2011-05-09T11:51:12Z") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of pancreatic B cell apoptosis") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of pancreatic beta cell apoptosis") +AnnotationAssertion( "negative regulation of type B pancreatic cell apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000675") +AnnotationAssertion(rdfs:label "negative regulation of type B pancreatic cell apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of type B pancreatic cell apoptotic process) + +AnnotationAssertion(Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of type B pancreatic cell apoptotic process.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2011-05-09T11:51:15Z") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of pancreatic B cell apoptosis") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of pancreatic beta cell apoptosis") +AnnotationAssertion( "positive regulation of type B pancreatic cell apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000676") +AnnotationAssertion(rdfs:label "positive regulation of type B pancreatic cell apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of cardiac muscle cell myoblast differentiation) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of cardiac muscle cell myoblast differentiation.") +AnnotationAssertion( "yaf") +AnnotationAssertion( "2011-05-25T09:08:01Z") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of myocardial precursor cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of cardiac myoblast differentiation") +AnnotationAssertion( "GO:2000690") +AnnotationAssertion(rdfs:label "regulation of cardiac muscle cell myoblast differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of cardiac muscle cell myoblast differentiation) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of cardiac muscle cell myoblast differentiation.") +AnnotationAssertion( "yaf") +AnnotationAssertion( "2011-05-25T09:08:06Z") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of myocardial precursor cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of cardiac myoblast differentiation") +AnnotationAssertion( "GO:2000691") +AnnotationAssertion(rdfs:label "negative regulation of cardiac muscle cell myoblast differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of epithelial cell differentiation involved in kidney development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") Annotation( "GOC:yaf") "Any process that modulates the frequency, rate or extent of epithelial cell differentiation involved in kidney development.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-05-16T04:23:52Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000696") +AnnotationAssertion(rdfs:label "regulation of epithelial cell differentiation involved in kidney development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of epithelial cell differentiation involved in kidney development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") Annotation( "GOC:yaf") "Any process that stops, prevents or reduces the frequency, rate or extent of epithelial cell differentiation involved in kidney development.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-05-16T04:23:55Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000697") +AnnotationAssertion(rdfs:label "negative regulation of epithelial cell differentiation involved in kidney development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of epithelial cell differentiation involved in kidney development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") Annotation( "GOC:yaf") "Any process that activates or increases the frequency, rate or extent of epithelial cell differentiation involved in kidney development.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-05-16T04:23:57Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000698") +AnnotationAssertion(rdfs:label "positive regulation of epithelial cell differentiation involved in kidney development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of cardiac muscle cell myoblast differentiation) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of cardiac muscle cell myoblast differentiation.") +AnnotationAssertion( "yaf") +AnnotationAssertion( "2011-05-25T09:08:09Z") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of myocardial precursor cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of cardiac myoblast differentiation") +AnnotationAssertion( "GO:2000700") +AnnotationAssertion(rdfs:label "positive regulation of cardiac muscle cell myoblast differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of cardiac muscle cell differentiation) + +AnnotationAssertion(Annotation( "GOC:BHF") "Any process that modulates the frequency, rate or extent of cardiac muscle cell differentiation.") +AnnotationAssertion( "vk") +AnnotationAssertion( "2011-06-08T10:51:06Z") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of cardiomyocyte differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of heart muscle cell differentiation") +AnnotationAssertion( "GO:2000725") +AnnotationAssertion(rdfs:label "regulation of cardiac muscle cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of cardiac muscle cell differentiation) + +AnnotationAssertion(Annotation( "GOC:BHF") "Any process that stops, prevents or reduces the frequency, rate or extent of cardiac muscle cell differentiation.") +AnnotationAssertion( "vk") +AnnotationAssertion( "2011-06-08T10:51:11Z") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of cardiomyocyte differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of heart muscle cell differentiation") +AnnotationAssertion( "GO:2000726") +AnnotationAssertion(rdfs:label "negative regulation of cardiac muscle cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of cardiac muscle cell differentiation) + +AnnotationAssertion(Annotation( "GOC:BHF") "Any process that activates or increases the frequency, rate or extent of cardiac muscle cell differentiation.") +AnnotationAssertion( "vk") +AnnotationAssertion( "2011-06-08T10:51:15Z") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of cardiomyocyte differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of heart muscle cell differentiation") +AnnotationAssertion( "GO:2000727") +AnnotationAssertion(rdfs:label "positive regulation of cardiac muscle cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of mesenchymal cell proliferation involved in ureter development) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of mesenchymal cell proliferation involved in ureter development.") +AnnotationAssertion( "yaf") +AnnotationAssertion( "2011-06-10T02:27:19Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of ureter mesenchymal cell proliferation") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of ureteral mesenchymal cell proliferation") +AnnotationAssertion( "GO:2000729") +AnnotationAssertion(rdfs:label "positive regulation of mesenchymal cell proliferation involved in ureter development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (regulation of stem cell differentiation) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of stem cell differentiation.") +AnnotationAssertion( "yaf") +AnnotationAssertion( "2011-06-14T02:05:16Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000736") +AnnotationAssertion(rdfs:label "regulation of stem cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of stem cell differentiation) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of stem cell differentiation.") +AnnotationAssertion( "yaf") +AnnotationAssertion( "2011-06-14T02:05:20Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000737") +AnnotationAssertion(rdfs:label "negative regulation of stem cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of stem cell differentiation) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of stem cell differentiation.") +AnnotationAssertion( "yaf") +AnnotationAssertion( "2011-06-14T02:05:23Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000738") +AnnotationAssertion(rdfs:label "positive regulation of stem cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of cytoplasmic translation) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of cytoplasmic translation.") +AnnotationAssertion( "vw") +AnnotationAssertion( "2011-06-20T10:39:19Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000765") +AnnotationAssertion(rdfs:label "regulation of cytoplasmic translation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of cytoplasmic translation) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic translation.") +AnnotationAssertion( "vw") +AnnotationAssertion( "2011-06-20T10:39:23Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000766") +AnnotationAssertion(rdfs:label "negative regulation of cytoplasmic translation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of cytoplasmic translation) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of cytoplasmic translation.") +AnnotationAssertion( "vw") +AnnotationAssertion( "2011-06-20T10:39:26Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000767") +AnnotationAssertion(rdfs:label "positive regulation of cytoplasmic translation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of nephron tubule epithelial cell differentiation) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of nephron tubule epithelial cell differentiation.") +AnnotationAssertion( "yaf") +AnnotationAssertion( "2011-06-22T11:55:06Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000768") +AnnotationAssertion(rdfs:label "positive regulation of nephron tubule epithelial cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of mesenchymal cell proliferation involved in lung development) + +AnnotationAssertion(Annotation( "PMID:21513708") "Any process that modulates the frequency, rate or extent of mesenchymal cell proliferation involved in lung development.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2011-06-24T01:53:50Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000790") +AnnotationAssertion(rdfs:label "regulation of mesenchymal cell proliferation involved in lung development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of mesenchymal cell proliferation involved in lung development) + +AnnotationAssertion(Annotation( "PMID:21513708") "Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal cell proliferation involved in lung development.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2011-06-24T01:53:53Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000791") +AnnotationAssertion(rdfs:label "negative regulation of mesenchymal cell proliferation involved in lung development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (positive regulation of mesenchymal cell proliferation involved in lung development) + +AnnotationAssertion(Annotation( "PMID:21513708") "Any process that activates or increases the frequency, rate or extent of mesenchymal cell proliferation involved in lung development.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2011-06-24T01:53:56Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000792") +AnnotationAssertion(rdfs:label "positive regulation of mesenchymal cell proliferation involved in lung development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (cell proliferation involved in heart valve development) + +AnnotationAssertion(Annotation( "GOC:BHF") "Any cell proliferation that is involved in heart valve development.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-06-24T03:12:15Z") +AnnotationAssertion(Annotation( "GOC:obol") "cell proliferation of cardiac valve development") +AnnotationAssertion(Annotation( "GOC:obol") "cell proliferation of heart valve development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000793") +AnnotationAssertion(rdfs:label "cell proliferation involved in heart valve development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of epithelial cell proliferation involved in lung morphogenesis) + +AnnotationAssertion(Annotation( "PMID:21513708") "Any process that modulates the frequency, rate or extent of epithelial cell proliferation involved in lung morphogenesis.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2011-06-25T07:22:38Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000794") +AnnotationAssertion(rdfs:label "regulation of epithelial cell proliferation involved in lung morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of epithelial cell proliferation involved in lung morphogenesis) + +AnnotationAssertion(Annotation( "PMID:21513708") "Any process that stops, prevents or reduces the frequency, rate or extent of epithelial cell proliferation involved in lung morphogenesis.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2011-06-25T07:22:42Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000795") +AnnotationAssertion(rdfs:label "negative regulation of epithelial cell proliferation involved in lung morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of bicellular tight junction assembly) + +AnnotationAssertion(Annotation( "GOC:BHF") "Any process that modulates the frequency, rate or extent of tight junction assembly.") +AnnotationAssertion( "vk") +AnnotationAssertion( "2011-07-06T01:08:28Z") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of tight junction formation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000810") +AnnotationAssertion(rdfs:label "regulation of bicellular tight junction assembly") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of myoblast proliferation) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of myoblast proliferation.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2011-07-12T03:06:04Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000818") +AnnotationAssertion(rdfs:label "negative regulation of myoblast proliferation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of grooming behavior) + +AnnotationAssertion(Annotation( "GOC:BHF") "Any process that modulates the frequency, rate or extent of grooming behavior.") +AnnotationAssertion( "rl") +AnnotationAssertion( "2011-07-14T04:48:12Z") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of grooming behaviour") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000821") +AnnotationAssertion(rdfs:label "regulation of grooming behavior") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (regulation of heart morphogenesis) + +AnnotationAssertion(Annotation( "GOC:BHF") "Any process that modulates the frequency, rate or extent of heart morphogenesis.") +AnnotationAssertion( "vk") +AnnotationAssertion( "2011-07-19T10:08:58Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of cardiac morphogenesis") +AnnotationAssertion( "GO:2000826") +AnnotationAssertion(rdfs:label "regulation of heart morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of parathyroid hormone secretion) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of parathyroid hormone secretion.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-07-26T08:37:53Z") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of PTH secretion") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of parathormone secretion") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of parathyrin secretion") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000828") +AnnotationAssertion(rdfs:label "regulation of parathyroid hormone secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of parathyroid hormone secretion) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of parathyroid hormone secretion.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-07-26T08:37:57Z") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of PTH secretion") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of parathormone secretion") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of parathyrin secretion") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000829") +AnnotationAssertion(rdfs:label "negative regulation of parathyroid hormone secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of parathyroid hormone secretion) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of parathyroid hormone secretion.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-07-26T08:38:00Z") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of PTH secretion") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of parathormone secretion") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of parathyrin secretion") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000830") +AnnotationAssertion(rdfs:label "positive regulation of parathyroid hormone secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of steroid hormone secretion) + +AnnotationAssertion(Annotation( "GOC:sl") "Any process that modulates the frequency, rate or extent of steroid hormone secretion.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-07-26T08:38:46Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000831") +AnnotationAssertion(rdfs:label "regulation of steroid hormone secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of steroid hormone secretion) + +AnnotationAssertion(Annotation( "GOC:sl") "Any process that stops, prevents or reduces the frequency, rate or extent of steroid hormone secretion.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-07-26T08:38:50Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000832") +AnnotationAssertion(rdfs:label "negative regulation of steroid hormone secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of steroid hormone secretion) + +AnnotationAssertion(Annotation( "GOC:sl") "Any process that activates or increases the frequency, rate or extent of steroid hormone secretion.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-07-26T08:38:51Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000833") +AnnotationAssertion(rdfs:label "positive regulation of steroid hormone secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of androgen secretion) + +AnnotationAssertion(Annotation( "GOC:sl") "Any process that modulates the frequency, rate or extent of androgen secretion.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-07-26T08:39:45Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000834") +AnnotationAssertion(rdfs:label "regulation of androgen secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of androgen secretion) + +AnnotationAssertion(Annotation( "GOC:sl") "Any process that stops, prevents or reduces the frequency, rate or extent of androgen secretion.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-07-26T08:39:48Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000835") +AnnotationAssertion(rdfs:label "negative regulation of androgen secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of androgen secretion) + +AnnotationAssertion(Annotation( "GOC:sl") "Any process that activates or increases the frequency, rate or extent of androgen secretion.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-07-26T08:39:51Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000836") +AnnotationAssertion(rdfs:label "positive regulation of androgen secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of testosterone secretion) + +AnnotationAssertion(Annotation( "GOC:sl") "Any process that modulates the frequency, rate or extent of testosterone secretion.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-07-26T08:42:29Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000843") +AnnotationAssertion(rdfs:label "regulation of testosterone secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of testosterone secretion) + +AnnotationAssertion(Annotation( "GOC:sl") "Any process that stops, prevents or reduces the frequency, rate or extent of testosterone secretion.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-07-26T08:42:33Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000844") +AnnotationAssertion(rdfs:label "negative regulation of testosterone secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of testosterone secretion) + +AnnotationAssertion(Annotation( "GOC:sl") "Any process that activates or increases the frequency, rate or extent of testosterone secretion.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-07-26T08:42:36Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000845") +AnnotationAssertion(rdfs:label "positive regulation of testosterone secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of corticosteroid hormone secretion) + +AnnotationAssertion(Annotation( "GOC:sl") "Any process that modulates the frequency, rate or extent of corticosteroid hormone secretion.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-07-26T08:43:38Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of corticosteroid secretion") +AnnotationAssertion( "GO:2000846") +AnnotationAssertion(rdfs:label "regulation of corticosteroid hormone secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (negative regulation of corticosteroid hormone secretion) + +AnnotationAssertion(Annotation( "GOC:sl") "Any process that stops, prevents or reduces the frequency, rate or extent of corticosteroid hormone secretion.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-07-26T08:43:42Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of corticosteroid secretion") +AnnotationAssertion( "GO:2000847") +AnnotationAssertion(rdfs:label "negative regulation of corticosteroid hormone secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of corticosteroid hormone secretion) + +AnnotationAssertion(Annotation( "GOC:sl") "Any process that activates or increases the frequency, rate or extent of corticosteroid hormone secretion.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-07-26T08:43:45Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of corticosteroid secretion") +AnnotationAssertion( "GO:2000848") +AnnotationAssertion(rdfs:label "positive regulation of corticosteroid hormone secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of glucocorticoid secretion) + +AnnotationAssertion(Annotation( "GOC:sl") "Any process that modulates the frequency, rate or extent of glucocorticoid secretion.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-07-26T08:44:43Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000849") +AnnotationAssertion(rdfs:label "regulation of glucocorticoid secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of glucocorticoid secretion) + +AnnotationAssertion(Annotation( "GOC:sl") "Any process that stops, prevents or reduces the frequency, rate or extent of glucocorticoid secretion.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-07-26T08:44:48Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000850") +AnnotationAssertion(rdfs:label "negative regulation of glucocorticoid secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of glucocorticoid secretion) + +AnnotationAssertion(Annotation( "GOC:sl") "Any process that activates or increases the frequency, rate or extent of glucocorticoid secretion.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-07-26T08:44:51Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000851") +AnnotationAssertion(rdfs:label "positive regulation of glucocorticoid secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of mineralocorticoid secretion) + +AnnotationAssertion(Annotation( "GOC:sl") "Any process that modulates the frequency, rate or extent of mineralocorticoid secretion.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-07-26T08:46:38Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000855") +AnnotationAssertion(rdfs:label "regulation of mineralocorticoid secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (negative regulation of mineralocorticoid secretion) + +AnnotationAssertion(Annotation( "GOC:sl") "Any process that stops, prevents or reduces the frequency, rate or extent of mineralocorticoid secretion.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-07-26T08:46:42Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000856") +AnnotationAssertion(rdfs:label "negative regulation of mineralocorticoid secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of mineralocorticoid secretion) + +AnnotationAssertion(Annotation( "GOC:sl") "Any process that activates or increases the frequency, rate or extent of mineralocorticoid secretion.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-07-26T08:46:45Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000857") +AnnotationAssertion(rdfs:label "positive regulation of mineralocorticoid secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of aldosterone secretion) + +AnnotationAssertion(Annotation( "GOC:sl") "Any process that modulates the frequency, rate or extent of aldosterone secretion.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-07-26T08:47:27Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000858") +AnnotationAssertion(rdfs:label "regulation of aldosterone secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (negative regulation of aldosterone secretion) + +AnnotationAssertion(Annotation( "GOC:sl") "Any process that stops, prevents or reduces the frequency, rate or extent of aldosterone secretion.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-07-26T08:47:31Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000859") +AnnotationAssertion(rdfs:label "negative regulation of aldosterone secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of aldosterone secretion) + +AnnotationAssertion(Annotation( "GOC:sl") "Any process that activates or increases the frequency, rate or extent of aldosterone secretion.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-07-26T08:47:34Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000860") +AnnotationAssertion(rdfs:label "positive regulation of aldosterone secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of progesterone secretion) + +AnnotationAssertion(Annotation( "GOC:sl") "Any process that modulates the frequency, rate or extent of progesterone secretion.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-07-26T08:51:14Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000870") +AnnotationAssertion(rdfs:label "regulation of progesterone secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of progesterone secretion) + +AnnotationAssertion(Annotation( "GOC:sl") "Any process that stops, prevents or reduces the frequency, rate or extent of progesterone secretion.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-07-26T08:51:19Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000871") +AnnotationAssertion(rdfs:label "negative regulation of progesterone secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of progesterone secretion) + +AnnotationAssertion(Annotation( "GOC:sl") "Any process that activates or increases the frequency, rate or extent of progesterone secretion.") +AnnotationAssertion( "bf") +AnnotationAssertion( "2011-07-26T08:51:22Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000872") +AnnotationAssertion(rdfs:label "positive regulation of progesterone secretion") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of pro-B cell differentiation) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of pro-B cell differentiation.") +AnnotationAssertion( "yaf") +AnnotationAssertion( "2011-08-02T03:05:45Z") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of pro-B lymphocyte differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of pro-B cell development") +AnnotationAssertion( "GO:2000973") +AnnotationAssertion(rdfs:label "regulation of pro-B cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of pro-B cell differentiation) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of pro-B cell differentiation.") +AnnotationAssertion( "yaf") +AnnotationAssertion( "2011-08-02T03:05:50Z") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of pro-B lymphocyte differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of pro-B cell development") +AnnotationAssertion( "GO:2000974") +AnnotationAssertion(rdfs:label "negative regulation of pro-B cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of pro-B cell differentiation) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of pro-B cell differentiation.") +AnnotationAssertion( "yaf") +AnnotationAssertion( "2011-08-02T03:05:53Z") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of pro-B lymphocyte differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of pro-B cell development") +AnnotationAssertion( "GO:2000975") +AnnotationAssertion(rdfs:label "positive regulation of pro-B cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of forebrain neuron differentiation) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of forebrain neuron differentiation.") +AnnotationAssertion( "yaf") +AnnotationAssertion( "2011-08-03T12:09:12Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000977") +AnnotationAssertion(rdfs:label "regulation of forebrain neuron differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of forebrain neuron differentiation) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of forebrain neuron differentiation.") +AnnotationAssertion( "yaf") +AnnotationAssertion( "2011-08-03T12:09:16Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000978") +AnnotationAssertion(rdfs:label "negative regulation of forebrain neuron differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of forebrain neuron differentiation) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of forebrain neuron differentiation.") +AnnotationAssertion( "yaf") +AnnotationAssertion( "2011-08-03T12:09:19Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000979") +AnnotationAssertion(rdfs:label "positive regulation of forebrain neuron differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of inner ear receptor cell differentiation) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of inner ear receptor cell differentiation.") +AnnotationAssertion( "yaf") +AnnotationAssertion( "2011-08-03T02:38:43Z") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of inner ear hair cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000980") +AnnotationAssertion(rdfs:label "regulation of inner ear receptor cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of inner ear receptor cell differentiation) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of inner ear receptor cell differentiation.") +AnnotationAssertion( "yaf") +AnnotationAssertion( "2011-08-03T02:38:47Z") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of inner ear hair cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000981") +AnnotationAssertion(rdfs:label "negative regulation of inner ear receptor cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of inner ear receptor cell differentiation) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of inner ear receptor cell differentiation.") +AnnotationAssertion( "yaf") +AnnotationAssertion( "2011-08-03T02:38:51Z") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of inner ear hair cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000982") +AnnotationAssertion(rdfs:label "positive regulation of inner ear receptor cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of cellulose catabolic process) + +AnnotationAssertion(Annotation( "GOC:mengo_curators") "Any process that modulates the frequency, rate or extent of cellulose catabolic process.") +AnnotationAssertion( "tt") +AnnotationAssertion( "2011-08-08T03:21:20Z") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of cellulose breakdown") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of cellulose catabolism") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of cellulose degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000997") +AnnotationAssertion(rdfs:label "regulation of cellulose catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of cellulose catabolic process) + +AnnotationAssertion(Annotation( "GOC:mengo_curators") "Any process that stops, prevents or reduces the frequency, rate or extent of cellulose catabolic process.") +AnnotationAssertion( "tt") +AnnotationAssertion( "2011-08-08T03:21:26Z") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of cellulose breakdown") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of cellulose catabolism") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of cellulose degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000998") +AnnotationAssertion(rdfs:label "negative regulation of cellulose catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of cellulose catabolic process) + +AnnotationAssertion(Annotation( "GOC:mengo_curators") "Any process that activates or increases the frequency, rate or extent of cellulose catabolic process.") +AnnotationAssertion( "tt") +AnnotationAssertion( "2011-08-08T03:21:30Z") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of cellulose breakdown") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of cellulose catabolism") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of cellulose degradation") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2000999") +AnnotationAssertion(rdfs:label "positive regulation of cellulose catabolic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of cellulose biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:mengo_curators") "Any process that modulates the frequency, rate or extent of cellulose biosynthetic process.") +AnnotationAssertion( "tt") +AnnotationAssertion( "2011-08-08T08:42:17Z") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of cellulose anabolism") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of cellulose biosynthesis") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of cellulose formation") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of cellulose synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2001006") +AnnotationAssertion(rdfs:label "regulation of cellulose biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of cellulose biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:mengo_curators") "Any process that stops, prevents or reduces the frequency, rate or extent of cellulose biosynthetic process.") +AnnotationAssertion( "tt") +AnnotationAssertion( "2011-08-08T08:42:24Z") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of cellulose anabolism") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of cellulose biosynthesis") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of cellulose formation") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of cellulose synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2001007") +AnnotationAssertion(rdfs:label "negative regulation of cellulose biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of cellulose biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:mengo_curators") "Any process that activates or increases the frequency, rate or extent of cellulose biosynthetic process.") +AnnotationAssertion( "tt") +AnnotationAssertion( "2011-08-08T08:42:29Z") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of cellulose anabolism") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of cellulose biosynthesis") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of cellulose formation") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of cellulose synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2001008") +AnnotationAssertion(rdfs:label "positive regulation of cellulose biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (mesenchymal cell differentiation involved in renal system development) + +AnnotationAssertion(Annotation( "GOC:mtg_kidney_jan10") Annotation( "GOC:obol") Annotation( "GOC:yaf") "The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of the renal system as it progresses from its formation to the mature state.") +AnnotationAssertion( "yaf") +AnnotationAssertion( "2011-08-09T04:05:14Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:obol") "mesenchymal cell differentiation involved in urinary system development") +AnnotationAssertion(Annotation( "GOC:obol") "mesenchymal cell differentiation involved in urinary tract development") +AnnotationAssertion( "GO:2001012") +AnnotationAssertion(rdfs:label "mesenchymal cell differentiation involved in renal system development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (epithelial cell proliferation involved in renal tubule morphogenesis) + +AnnotationAssertion(Annotation( "GOC:obol") "Any epithelial cell proliferation that is involved in renal tubule morphogenesis.") +AnnotationAssertion( "yaf") +AnnotationAssertion( "2011-08-12T11:37:29Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2001013") +AnnotationAssertion(rdfs:label "epithelial cell proliferation involved in renal tubule morphogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of skeletal muscle cell differentiation) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of skeletal muscle cell differentiation.") +AnnotationAssertion( "yaf") +AnnotationAssertion( "2011-08-11T08:54:37Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2001014") +AnnotationAssertion(rdfs:label "regulation of skeletal muscle cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of skeletal muscle cell differentiation) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle cell differentiation.") +AnnotationAssertion( "yaf") +AnnotationAssertion( "2011-08-11T08:54:41Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2001015") +AnnotationAssertion(rdfs:label "negative regulation of skeletal muscle cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of skeletal muscle cell differentiation) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of skeletal muscle cell differentiation.") +AnnotationAssertion( "yaf") +AnnotationAssertion( "2011-08-11T08:54:44Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2001016") +AnnotationAssertion(rdfs:label "positive regulation of skeletal muscle cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of retrograde axon cargo transport) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of retrograde axon cargo transport.") +AnnotationAssertion( "kmv") +AnnotationAssertion( "2011-08-11T09:44:42Z") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of retrograde axonal transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2001017") +AnnotationAssertion(rdfs:label "regulation of retrograde axon cargo transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of retrograde axon cargo transport) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of retrograde axon cargo transport.") +AnnotationAssertion( "kmv") +AnnotationAssertion( "2011-08-11T09:44:46Z") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of retrograde axonal transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2001018") +AnnotationAssertion(rdfs:label "negative regulation of retrograde axon cargo transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of retrograde axon cargo transport) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of retrograde axon cargo transport.") +AnnotationAssertion( "kmv") +AnnotationAssertion( "2011-08-11T09:44:49Z") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of retrograde axonal transport") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2001019") +AnnotationAssertion(rdfs:label "positive regulation of retrograde axon cargo transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of endothelial cell chemotaxis) + +AnnotationAssertion(Annotation( "GOC:BHF") "Any process that modulates the frequency, rate or extent of endothelial cell chemotaxis.") +AnnotationAssertion( "rl") +AnnotationAssertion( "2011-08-22T01:07:26Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2001026") +AnnotationAssertion(rdfs:label "regulation of endothelial cell chemotaxis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of endothelial cell chemotaxis) + +AnnotationAssertion(Annotation( "GOC:BHF") "Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell chemotaxis.") +AnnotationAssertion( "rl") +AnnotationAssertion( "2011-08-22T01:07:31Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2001027") +AnnotationAssertion(rdfs:label "negative regulation of endothelial cell chemotaxis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of endothelial cell chemotaxis) + +AnnotationAssertion(Annotation( "GOC:BHF") "Any process that activates or increases the frequency, rate or extent of endothelial cell chemotaxis.") +AnnotationAssertion( "rl") +AnnotationAssertion( "2011-08-22T01:07:34Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2001028") +AnnotationAssertion(rdfs:label "positive regulation of endothelial cell chemotaxis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of tongue muscle cell differentiation) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of tongue muscle cell differentiation.") +AnnotationAssertion( "yaf") +AnnotationAssertion( "2011-08-24T11:10:16Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2001035") +AnnotationAssertion(rdfs:label "regulation of tongue muscle cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of tongue muscle cell differentiation) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of tongue muscle cell differentiation.") +AnnotationAssertion( "yaf") +AnnotationAssertion( "2011-08-24T11:10:20Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2001036") +AnnotationAssertion(rdfs:label "negative regulation of tongue muscle cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of tongue muscle cell differentiation) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of tongue muscle cell differentiation.") +AnnotationAssertion( "yaf") +AnnotationAssertion( "2011-08-24T11:10:22Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2001037") +AnnotationAssertion(rdfs:label "positive regulation of tongue muscle cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of tendon cell differentiation) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of tendon cell differentiation.") +AnnotationAssertion( "yaf") +AnnotationAssertion( "2011-09-01T09:20:32Z") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of muscle attachment cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of tenocyte differentiation") +AnnotationAssertion( "GO:2001049") +AnnotationAssertion(rdfs:label "regulation of tendon cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of tendon cell differentiation) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of tendon cell differentiation.") +AnnotationAssertion( "yaf") +AnnotationAssertion( "2011-09-01T09:20:38Z") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of muscle attachment cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of tenocyte differentiation") +AnnotationAssertion( "GO:2001050") +AnnotationAssertion(rdfs:label "negative regulation of tendon cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of tendon cell differentiation) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of tendon cell differentiation.") +AnnotationAssertion( "yaf") +AnnotationAssertion( "2011-09-01T09:20:42Z") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of muscle attachment cell differentiation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of tenocyte differentiation") +AnnotationAssertion( "GO:2001051") +AnnotationAssertion(rdfs:label "positive regulation of tendon cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of mesenchymal cell apoptotic process) + +AnnotationAssertion(Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of mesenchymal cell apoptotic process.") +AnnotationAssertion( "yaf") +AnnotationAssertion( "2011-09-08T02:49:59Z") +AnnotationAssertion( "regulation of mesenchymal cell apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2001053") +AnnotationAssertion(rdfs:label "regulation of mesenchymal cell apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of mesenchymal cell apoptotic process) + +AnnotationAssertion(Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal cell apoptotic process.") +AnnotationAssertion( "yaf") +AnnotationAssertion( "2011-09-08T02:50:05Z") +AnnotationAssertion( "negative regulation of mesenchymal cell apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2001054") +AnnotationAssertion(rdfs:label "negative regulation of mesenchymal cell apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of mesenchymal cell apoptotic process) + +AnnotationAssertion(Annotation( "GOC:mtg_apoptosis") Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of mesenchymal cell apoptotic process.") +AnnotationAssertion( "yaf") +AnnotationAssertion( "2011-09-08T02:50:09Z") +AnnotationAssertion( "positive regulation of mesenchymal cell apoptosis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2001055") +AnnotationAssertion(rdfs:label "positive regulation of mesenchymal cell apoptotic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (glycogen binding) + +AnnotationAssertion(Annotation( "GOC:mengo_curators") "Binding to glycogen.") +AnnotationAssertion( "jl") +AnnotationAssertion( "2011-09-14T12:01:06Z") +AnnotationAssertion( "molecular_function") +AnnotationAssertion(Annotation( "GOC:obol") "animal starch binding") +AnnotationAssertion(Annotation( "GOC:obol") "liver starch binding") +AnnotationAssertion( "GO:2001069") +AnnotationAssertion(rdfs:label "glycogen binding") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of phospholipid transport) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of phospholipid transport.") +AnnotationAssertion( "kmv") +AnnotationAssertion( "2011-10-14T06:16:06Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2001138") +AnnotationAssertion(rdfs:label "regulation of phospholipid transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of phospholipid transport) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of phospholipid transport.") +AnnotationAssertion( "kmv") +AnnotationAssertion( "2011-10-14T06:16:11Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2001139") +AnnotationAssertion(rdfs:label "negative regulation of phospholipid transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of phospholipid transport) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of phospholipid transport.") +AnnotationAssertion( "kmv") +AnnotationAssertion( "2011-10-14T06:16:14Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2001140") +AnnotationAssertion(rdfs:label "positive regulation of phospholipid transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of RNA biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:dph") "Any process that modulates the frequency, rate or extent of RNA biosynthetic process.") +AnnotationAssertion( "dph") +AnnotationAssertion( "2011-10-17T11:36:25Z") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of RNA anabolism") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of RNA biosynthesis") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of RNA formation") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of RNA synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2001141") +AnnotationAssertion(rdfs:label "regulation of RNA biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of renal water transport) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of renal water transport.") +AnnotationAssertion( "yaf") +AnnotationAssertion( "2011-10-24T11:37:51Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2001151") +AnnotationAssertion(rdfs:label "regulation of renal water transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (negative regulation of renal water transport) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of renal water transport.") +AnnotationAssertion( "yaf") +AnnotationAssertion( "2011-10-24T11:37:57Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2001152") +AnnotationAssertion(rdfs:label "negative regulation of renal water transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (positive regulation of renal water transport) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of renal water transport.") +AnnotationAssertion( "yaf") +AnnotationAssertion( "2011-10-24T11:38:01Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2001153") +AnnotationAssertion(rdfs:label "positive regulation of renal water transport") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ) + +# Class: (regulation of ATP biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of ATP biosynthetic process.") +AnnotationAssertion( "kmv") +AnnotationAssertion( "2011-10-26T03:18:03Z") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of ATP anabolism") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of ATP biosynthesis") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of ATP formation") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of ATP synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of ATP regeneration") +AnnotationAssertion( "GO:2001169") +AnnotationAssertion(rdfs:label "regulation of ATP biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of ATP biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of ATP biosynthetic process.") +AnnotationAssertion( "kmv") +AnnotationAssertion( "2011-10-26T03:18:13Z") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of ATP anabolism") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of ATP biosynthesis") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of ATP formation") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of ATP synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of ATP regeneration") +AnnotationAssertion( "GO:2001170") +AnnotationAssertion(rdfs:label "negative regulation of ATP biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of ATP biosynthetic process) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of ATP biosynthetic process.") +AnnotationAssertion( "kmv") +AnnotationAssertion( "2011-10-26T03:18:26Z") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of ATP anabolism") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of ATP biosynthesis") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of ATP formation") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of ATP synthesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of ATP regeneration") +AnnotationAssertion( "GO:2001171") +AnnotationAssertion(rdfs:label "positive regulation of ATP biosynthetic process") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of dendritic cell differentiation) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of dendritic cell differentiation.") +AnnotationAssertion( "yaf") +AnnotationAssertion( "2011-11-04T02:01:27Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2001198") +AnnotationAssertion(rdfs:label "regulation of dendritic cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of dendritic cell differentiation) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell differentiation.") +AnnotationAssertion( "yaf") +AnnotationAssertion( "2011-11-04T02:01:33Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2001199") +AnnotationAssertion(rdfs:label "negative regulation of dendritic cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of dendritic cell differentiation) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of dendritic cell differentiation.") +AnnotationAssertion( "yaf") +AnnotationAssertion( "2011-11-04T02:01:36Z") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2001200") +AnnotationAssertion(rdfs:label "positive regulation of dendritic cell differentiation") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of osteoclast development) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of osteoclast development.") +AnnotationAssertion( "yaf") +AnnotationAssertion( "2011-11-10T10:58:59Z") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of osteoclast cell development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2001204") +AnnotationAssertion(rdfs:label "regulation of osteoclast development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of osteoclast development) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of osteoclast development.") +AnnotationAssertion( "yaf") +AnnotationAssertion( "2011-11-10T10:59:06Z") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of osteoclast cell development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2001205") +AnnotationAssertion(rdfs:label "negative regulation of osteoclast development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (positive regulation of osteoclast development) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of osteoclast development.") +AnnotationAssertion( "yaf") +AnnotationAssertion( "2011-11-10T10:59:12Z") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of osteoclast cell development") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2001206") +AnnotationAssertion(rdfs:label "positive regulation of osteoclast development") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (regulation of vasculogenesis) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of vasculogenesis.") +AnnotationAssertion( "yaf") +AnnotationAssertion( "2011-11-15T01:22:31Z") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of vascular morphogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2001212") +AnnotationAssertion(rdfs:label "regulation of vasculogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (negative regulation of vasculogenesis) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of vasculogenesis.") +AnnotationAssertion( "yaf") +AnnotationAssertion( "2011-11-15T01:22:36Z") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of vascular morphogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2001213") +AnnotationAssertion(rdfs:label "negative regulation of vasculogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of vasculogenesis) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of vasculogenesis.") +AnnotationAssertion( "yaf") +AnnotationAssertion( "2011-11-15T01:22:39Z") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of vascular morphogenesis") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2001214") +AnnotationAssertion(rdfs:label "positive regulation of vasculogenesis") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of neuron migration) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that modulates the frequency, rate or extent of neuron migration.") +AnnotationAssertion( "kmv") +AnnotationAssertion( "2011-11-17T10:01:38Z") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of neuron chemotaxis") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of neuronal migration") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:obol") "regulation of neuron guidance") +AnnotationAssertion( "GO:2001222") +AnnotationAssertion(rdfs:label "regulation of neuron migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectAllValuesFrom( )) + +# Class: (negative regulation of neuron migration) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of neuron migration.") +AnnotationAssertion( "kmv") +AnnotationAssertion( "2011-11-17T10:01:45Z") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of neuron chemotaxis") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of neuronal migration") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of neuron guidance") +AnnotationAssertion( "GO:2001223") +AnnotationAssertion(rdfs:label "negative regulation of neuron migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of neuron migration) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of neuron migration.") +AnnotationAssertion( "kmv") +AnnotationAssertion( "2011-11-17T10:01:49Z") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of neuron chemotaxis") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of neuronal migration") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of neuron guidance") +AnnotationAssertion( "GO:2001224") +AnnotationAssertion(rdfs:label "positive regulation of neuron migration") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (regulation of apoptotic signaling pathway) + +AnnotationAssertion(Annotation( "GOC:mtg_apoptosis") "Any process that modulates the frequency, rate or extent of apoptotic signaling pathway.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2011-11-24T01:20:49Z") +AnnotationAssertion(Annotation( "GOC:mah") "regulation of apoptotic signalling pathway") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2001233") +AnnotationAssertion(rdfs:label "regulation of apoptotic signaling pathway") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (negative regulation of apoptotic signaling pathway) + +AnnotationAssertion(Annotation( "GOC:mtg_apoptosis") "Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic signaling pathway.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2011-11-24T01:20:54Z") +AnnotationAssertion(Annotation( "GOC:mah") "negative regulation of apoptotic signalling pathway") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2001234") +AnnotationAssertion(rdfs:label "negative regulation of apoptotic signaling pathway") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (positive regulation of apoptotic signaling pathway) + +AnnotationAssertion(Annotation( "GOC:mtg_apoptosis") "Any process that activates or increases the frequency, rate or extent of apoptotic signaling pathway.") +AnnotationAssertion( "pr") +AnnotationAssertion( "2011-11-24T01:20:58Z") +AnnotationAssertion(Annotation( "GOC:mah") "positive regulation of apoptotic signalling pathway") +AnnotationAssertion( "biological_process") +AnnotationAssertion( "GO:2001235") +AnnotationAssertion(rdfs:label "positive regulation of apoptotic signaling pathway") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf(Annotation( "https://github.com/geneontology/go-ontology/issues/13926") ObjectSomeValuesFrom( )) + +# Class: (negative regulation of chromosome organization) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that stops, prevents or reduces the frequency, rate or extent of chromosome organization.") +AnnotationAssertion( "yaf") +AnnotationAssertion( "2011-12-02T02:01:20Z") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of chromosome organisation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of chromosome organization and biogenesis") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of maintenance of genome integrity") +AnnotationAssertion(Annotation( "GOC:obol") "negative regulation of nuclear genome maintenance") +AnnotationAssertion( "GO:2001251") +AnnotationAssertion(rdfs:label "negative regulation of chromosome organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (positive regulation of chromosome organization) + +AnnotationAssertion(Annotation( "GOC:obol") "Any process that activates or increases the frequency, rate or extent of chromosome organization.") +AnnotationAssertion( "yaf") +AnnotationAssertion( "2011-12-02T02:01:26Z") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of chromosome organisation") +AnnotationAssertion( "biological_process") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of chromosome organization and biogenesis") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of maintenance of genome integrity") +AnnotationAssertion(Annotation( "GOC:obol") "positive regulation of nuclear genome maintenance") +AnnotationAssertion( "GO:2001252") +AnnotationAssertion(rdfs:label "positive regulation of chromosome organization") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) + +# Class: (data item) + +AnnotationAssertion( "data item"@en) +AnnotationAssertion(rdfs:label "data item"@en) +SubClassOf( ) + +# Class: (information content entity) + +AnnotationAssertion( "information content entity"@en) +AnnotationAssertion(rdfs:label "information content entity"@en) +SubClassOf( ) + +# Class: (curation status specification) + +AnnotationAssertion( "curation status specification"@en) +AnnotationAssertion( ) +AnnotationAssertion( "The curation status of the term. The allowed values come from an enumerated list of predefined terms. See the specification of these instances for more detailed definitions of each enumerated value."@en) +AnnotationAssertion( "Better to represent curation as a process with parts and then relate labels to that process (in IAO meeting)"@en) +AnnotationAssertion( "PERSON:Bill Bug"@en) +AnnotationAssertion( "GROUP:OBI:"@en) +AnnotationAssertion( "OBI_0000266"@en) +AnnotationAssertion(rdfs:label "curation status specification"@en) +EquivalentClasses( ObjectOneOf( )) +SubClassOf( ) + +# Class: (data about an ontology part) + +AnnotationAssertion( "data about an ontology part"@en) +AnnotationAssertion( "Data about an ontology part is a data item about a part of an ontology, for example a term"@en) +AnnotationAssertion( "Person:Alan Ruttenberg"@en) +AnnotationAssertion(rdfs:label "data about an ontology part"@en) +SubClassOf( ) + +# Class: (obsolescence reason specification) + +AnnotationAssertion( "obsolescence reason specification"@en) +AnnotationAssertion( ) +AnnotationAssertion( "The reason for which a term has been deprecated. The allowed values come from an enumerated list of predefined terms. See the specification of these instances for more detailed definitions of each enumerated value."@en) +AnnotationAssertion( "The creation of this class has been inspired in part by Werner Ceusters' paper, Applying evolutionary terminology auditing to the Gene Ontology."@en) +AnnotationAssertion( "PERSON: Alan Ruttenberg"@en) +AnnotationAssertion( "PERSON: Melanie Courtot"@en) +AnnotationAssertion(rdfs:label "obsolescence reason specification"@en) +EquivalentClasses( ObjectOneOf( )) +SubClassOf( ) + +# Class: (denotator type) + +AnnotationAssertion( "denotator type"@en) +AnnotationAssertion( "The Basic Formal Ontology ontology makes a distinction between Universals and defined classes, where the formal are \"natural kinds\" and the latter arbitrary collections of entities."@en) +AnnotationAssertion( "A denotator type indicates how a term should be interpreted from an ontological perspective."@en) +AnnotationAssertion( "Alan Ruttenberg"@en) +AnnotationAssertion( "Barry Smith, Werner Ceusters"@en) +AnnotationAssertion(rdfs:label "denotator type"@en) +EquivalentClasses( ObjectOneOf( )) +SubClassOf( ) + # Class: (body part movement) AnnotationAssertion( "A change of place or position of part of an organism that does not involve the entire organism [NBO:SMAC]") @@ -55215,6 +137526,30 @@ AnnotationAssertion( "grooming behavior") SubClassOf( ) +# Class: (regulation of eating behavior) + +AnnotationAssertion(Annotation( "NBO:GVG") "A feeding behavior associated with the intake or the frequency of intake or preference or manner of intake of food.") +AnnotationAssertion( "2011-04-14T01:20:02Z") +AnnotationAssertion( "George Gkoutos") +AnnotationAssertion( "eating behaviour") +AnnotationAssertion( "behavior_ontology") +AnnotationAssertion( "GO:0042755") +AnnotationAssertion(rdfs:label "regulation of eating behavior") +EquivalentClasses( ObjectSomeValuesFrom( )) +SubClassOf( ) + +# Class: (regulation of drinking behavior) + +AnnotationAssertion(Annotation( "NBO:GVG") "A feeding behavior associated with the intake or the frequency of intake or preference or manner of intake of liquids.") +AnnotationAssertion( "2011-04-14T01:20:02Z") +AnnotationAssertion( "George Gkoutos") +AnnotationAssertion( "drinking behaviour") +AnnotationAssertion( "behavior_ontology") +AnnotationAssertion( "GO:0042756") +AnnotationAssertion(rdfs:label "regulation of drinking behavior") +EquivalentClasses( ObjectSomeValuesFrom( )) +SubClassOf( ) + # Class: (chewing) AnnotationAssertion( "The act of repeated grinding, tearing, and or crushing with teeth or jaws [NBO:SMAC]") @@ -55236,8 +137571,42 @@ AnnotationAssertion( "behavior_ontology") AnnotationAssertion( "GO:0007631") AnnotationAssertion(rdfs:label "feeding behavior") +EquivalentClasses( ObjectIntersectionOf( ObjectUnionOf(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )))) SubClassOf( ) +# Class: (liquid consumption) + +AnnotationAssertion(Annotation( "NBO:GVG") "A behavior associated with the intake of liquid.") +AnnotationAssertion( "2011-03-31T12:40:37Z") +AnnotationAssertion( "George Gkoutos") +AnnotationAssertion( "behavior_ontology") +AnnotationAssertion(rdfs:label "liquid consumption") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (water consumption) + +AnnotationAssertion(Annotation( "NBO:GVG") "A drinking behavior associated with the intake of water.") +AnnotationAssertion( "2011-03-31T12:41:14Z") +AnnotationAssertion( "George Gkoutos") +AnnotationAssertion( "behavior_ontology") +AnnotationAssertion( "GO:0045187") +AnnotationAssertion(rdfs:label "water consumption") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (food consumption) + +AnnotationAssertion(Annotation( "NBO:GVG") "A feeding behavior associated with the intake of food.") +AnnotationAssertion( "2011-03-31T12:42:46Z") +AnnotationAssertion( "George Gkoutos") +AnnotationAssertion( "behavior_ontology") +AnnotationAssertion(rdfs:label "food consumption") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (sensation behavior) AnnotationAssertion(Annotation( "NBO:GVG") "Cognitive perception of a sensation by any of the five senses -- vision, touch, smell, taste, and hearing.") @@ -55332,6 +137701,28 @@ AnnotationAssertion( "posture") SubClassOf( ) +# Class: (body posture) + +AnnotationAssertion(Annotation( "NBO:GVG") "Intentionally or habitually assumed arrangement of the body.") +AnnotationAssertion( "2011-04-06T09:30:45Z") +AnnotationAssertion( "George Gkoutos") +AnnotationAssertion( "behavior_ontology") +AnnotationAssertion(rdfs:label "body posture") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (limb posture) + +AnnotationAssertion(Annotation( "NBO:GVG") "Intentionally or habitually assumed arrangement of the limbs.") +AnnotationAssertion( "2011-04-06T09:31:06Z") +AnnotationAssertion( "George Gkoutos") +AnnotationAssertion( "behavior_ontology") +AnnotationAssertion(rdfs:label "limb posture") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (gait) AnnotationAssertion( "\"The pattern of movement of the limbs of animals, characterized by elements of progression, stability, speed and length over the ground.\" [MP:0001406]") @@ -55360,6 +137751,7 @@ AnnotationAssertion( "reflex behaviour") AnnotationAssertion( "behavior_ontology") AnnotationAssertion(rdfs:label "reflexive behavior") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) @@ -55440,6 +137832,15 @@ AnnotationAssertion( "perception behavior by means") SubClassOf( ) +# Class: (regulation of behavior) + +AnnotationAssertion( "\"Any process that modulates the frequency, rate or extent of behavior, the specific actions or reactions of an organism in response to external or internal stimuli.\" [GO:0050795]") +AnnotationAssertion( "George Gkoutos") +AnnotationAssertion( "GO:0050795") +AnnotationAssertion(rdfs:label "regulation of behavior"@en) +EquivalentClasses( ObjectSomeValuesFrom( )) +SubClassOf( ) + # Class: (consumption behavior) AnnotationAssertion(Annotation( "NBOC:GVG") "Behavior related to the intake of substances.") @@ -55448,6 +137849,30 @@ AnnotationAssertion( "consumption behavior"@en) SubClassOf( ) +# Class: (regulation of consumption behavior) + +AnnotationAssertion(Annotation( "NBOC:GVG") "Any process that modulates the frequency, rate or extent of consumption behavior, the specific actions or reactions of an organism in response to external or internal stimuli.") +AnnotationAssertion( "George Gkoutos") +AnnotationAssertion(rdfs:label "regulation of consumption behavior"@en) +EquivalentClasses( ObjectSomeValuesFrom( )) +SubClassOf( ) + +# Class: (regulation of feeding behavior) + +AnnotationAssertion(Annotation( "NBOC:GVG") "Any process that modulates the frequency, rate or extent of consumption of food or liquid") +AnnotationAssertion( "George Gkoutos") +AnnotationAssertion(rdfs:label "regulation of feeding behavior"@en) +EquivalentClasses( ObjectSomeValuesFrom( ObjectUnionOf( ))) +SubClassOf( ) + +# Class: (regulation of water consumption) + +AnnotationAssertion(Annotation( "NBOC:GVG") "Any process that modulates the frequency, rate or extent of water consumption, the specific actions or reactions of an organism in response to external or internal stimuli.") +AnnotationAssertion( "George Gkoutos") +AnnotationAssertion(rdfs:label "regulation of water consumption"@en) +EquivalentClasses( ObjectSomeValuesFrom( )) +SubClassOf( ) + # Class: (root) AnnotationAssertion( "GC_ID:1") @@ -60926,6 +143351,33 @@ AnnotationAssertion( "spatial pattern") SubClassOf( ) +# Class: (qualitative) + +AnnotationAssertion( "quality") +AnnotationAssertion( "PATO:0000068") +AnnotationAssertion(rdfs:comment "TODO: define this or obsolete it and move children somewhere else.") +AnnotationAssertion(rdfs:label "qualitative") +SubClassOf( ) + +# Class: (deviation (from_normal)) + +AnnotationAssertion(Annotation( "PATOC:GVG") "A quality inhering in a bearer by virtue of the whether the bearer differs from normal or average.") +AnnotationAssertion( "quality") +AnnotationAssertion( "PATO:0000069") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "deviation (from_normal)") +SubClassOf( ) + +# Class: (size) + +AnnotationAssertion(Annotation( "WordNet:WordNet") "A morphology quality inhering in a bearer by virtue of the bearer's physical magnitude.") +AnnotationAssertion( "quality") +AnnotationAssertion( "PATO:0000117") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "size") +SubClassOf( ) + # Class: (closure) AnnotationAssertion(Annotation( "PATOC:CJM") Annotation( "PATOC:GVG") "A morphological quality pertaining to the degree to which an object contains an opening, aperture, orifice or vent.") @@ -61066,6 +143518,37 @@ AnnotationAssertion( "uncoiled") SubClassOf( ) +# Class: (normal) + +AnnotationAssertion(Annotation( "PATOC:GVG") "A quality inhering in a bearer by virtue of the bearer's exhibiting no deviation from normal or average.") +AnnotationAssertion( ) +AnnotationAssertion( "quality") +AnnotationAssertion( "average") +AnnotationAssertion( "PATO:0000461") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "normal") +SubClassOf( ) + +# Class: (increased size) + +AnnotationAssertion(Annotation( "PATOC:GVG") "A size quality which is relatively high.") +AnnotationAssertion( ) +AnnotationAssertion( "PATO:0001202") +AnnotationAssertion( "quality") +AnnotationAssertion( "big") +AnnotationAssertion( "enlarged") +AnnotationAssertion( "expanded") +AnnotationAssertion( "great") +AnnotationAssertion( "large") +AnnotationAssertion( "PATO:0000586") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "increased size") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + # Class: (vestigial) AnnotationAssertion(Annotation( "PATOC:MAH") "A quality inhering in a bearer by virtue of the bearer's being a remnant structure from earlier development or evolution.") @@ -61391,6 +143874,16 @@ AnnotationAssertion( "haploid") SubClassOf( ) +# Class: (polyploid) + +AnnotationAssertion(Annotation( "Wikipedia:http://en.wikipedia.org/wiki/Polyploid") "A ploidy quality inhering in a bearer by virtue of the bearer's containing more than two homologous sets of chromosomes.") +AnnotationAssertion( "quality") +AnnotationAssertion( "PATO:0001377") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "polyploid") +SubClassOf( ) + # Class: (euploid) AnnotationAssertion(Annotation( "Wikipedia:http://en.wikipedia.org/wiki/Euploid") "A ploidy quality inhering in a bearer by virtue of the bearer's containing an integral multiple of the monoploid number, possibly excluding the sex-determining chromosomes.") @@ -61401,6 +143894,17 @@ AnnotationAssertion( "euploid") SubClassOf( ) +# Class: (diploid) + +AnnotationAssertion(Annotation( "Wikipedia:http://en.wikipedia.org/wiki/Diploid") "A ploidy quality inhering in a bearer by virtue of the bearer's having two copies (homologs) of each chromosome, usually one from the mother and one from the father.") +AnnotationAssertion( "quality") +AnnotationAssertion( "PATO:0001394") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:comment "The exact number may be one or two different from the 2n number and still be classified as diploidy (although with aneuploidy). Nearly all mammals are diploid organisms, although all individuals have some small fraction of cells that are polyploidy.") +AnnotationAssertion(rdfs:label "diploid") +SubClassOf( ) + # Class: (cellular quality) AnnotationAssertion(Annotation( "PATOC:GVG") "A monadic quality of continuant that exists at the cellular level of organisation.") @@ -61409,6 +143913,51 @@ AnnotationAssertion( "cellular quality") SubClassOf( ) +# Class: (cellular potency) + +AnnotationAssertion(Annotation( "PATOC:GVG") "A cellular quality that arises by virtue of whether the bearer's disposition to differentiate into one or more mature cell types.") +AnnotationAssertion( "quality") +AnnotationAssertion( "PATO:0001397") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "cellular potency") +SubClassOf( ) + +# Class: (unipotent) + +AnnotationAssertion(Annotation( "Wikipedia:http://en.wikipedia.org/wiki/Unipotent") "A cellular potency that is the capacity to produce only one differentiated cell type.") +AnnotationAssertion( "quality") +AnnotationAssertion( "PATO:0001400") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:comment "Unipotent cells have the quality of self-renewal which distinguishes them from non-stem cells.") +AnnotationAssertion(rdfs:label "unipotent") +SubClassOf( ) + +# Class: (oligopotent) + +AnnotationAssertion(Annotation( "PATOC:MAH") "A cellular potency that is the capacity to form multiple differentiated cell types of a specific lineage and lack self renewing capacity.") +AnnotationAssertion( "quality") +AnnotationAssertion( "PATO:0001401") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:comment "Less potent than multipotent, often thought of as precursor or progenitor cell status.") +AnnotationAssertion(rdfs:label "oligopotent") +SubClassOf( ) + +# Class: (multipotent) + +AnnotationAssertion(Annotation( "Wikipedia:http://en.wikipedia.org/wiki/Multipotent") "A cellular potency that is the capacity to form multiple differentiated cell types.") +AnnotationAssertion( "quality") +AnnotationAssertion( "PATO:0001402") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "multipotent") +SubClassOf( ) + # Class: (nucleate quality) AnnotationAssertion(Annotation( "PATOC:GVG") "A cellular quality inhering in a bearer by virtue of bearer's number of nuclei.") @@ -61429,6 +143978,49 @@ AnnotationAssertion( "anucleate") SubClassOf( ) +# Class: (binucleate) + +AnnotationAssertion(Annotation( "Biology-online:Biology-online") "A nucleate quality inhering in a bearer by virtue of the bearer's having two nuclei.") +AnnotationAssertion( "quality") +AnnotationAssertion( "PATO:0001406") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "binucleate") +SubClassOf( ) + +# Class: (mononucleate) + +AnnotationAssertion(Annotation( "Biology-online:Biology-online") "A nucleate quality inhering in a bearer by virtue of the bearer's having one nucleus.") +AnnotationAssertion( "quality") +AnnotationAssertion( "PATO:0001407") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "mononucleate") +SubClassOf( ) + +# Class: (ciliatedness) + +AnnotationAssertion(Annotation( "Wikipedia:http://en.wikipedia.org/wiki/Ciliated") "A cellular quality inhering in a bearer by virtue of the bearer's having thin, tail-like projections extending outwards from the cell body.") +AnnotationAssertion( "quality") +AnnotationAssertion( "PATO:0001408") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "ciliatedness") +SubClassOf( ) + +# Class: (striated) + +AnnotationAssertion(Annotation( "Biology-online:Biology-online") "A shape quality inhering in a bearer by virtue of the bearer's being marked by narrow lines or grooves, usually parallel.") +AnnotationAssertion( "quality") +AnnotationAssertion( "PATO:0001410") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "striated") +SubClassOf( ) + # Class: (sharp) AnnotationAssertion(Annotation( "PATOC:GVG") "A shape quality inhering in a bearer by virtue of the bearer's terminating in a point or edge.") @@ -61439,6 +144031,17 @@ AnnotationAssertion( "sharp") SubClassOf( ) +# Class: (buoyancy) + +AnnotationAssertion(Annotation( "PATOC:GVG") "A physical quality inhering in a bearer by virtue of the bearer's disposition to rise or float in a fluid medium such as water or air.") +AnnotationAssertion( "quality") +AnnotationAssertion( "PATO:0001420") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "buoyancy") +SubClassOf( ) + # Class: (dead) AnnotationAssertion(Annotation( "PATOC:GVG") "A viability quality inhering in a bearer by virtue of the cessation of the bearer's life.") @@ -61478,6 +144081,17 @@ AnnotationAssertion( "tapered") SubClassOf( ) +# Class: (immature) + +AnnotationAssertion(Annotation( "Merriam-Webster:Merriam-Webster") "A quality inhering in a bearer by virtue of the bearer's lacking complete growth, differentiation, or development.") +AnnotationAssertion( ) +AnnotationAssertion( "quality") +AnnotationAssertion( "underdeveloped") +AnnotationAssertion( "PATO:0001501") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "immature") +SubClassOf( ) + # Class: (flexibility) AnnotationAssertion(Annotation( "merriam-webster:merriam-webster") "A physical quality inhering in a bearer by virtue of the bearer's disposition to being turned, bowed, or twisted without breaking.") @@ -61541,6 +144155,20 @@ AnnotationAssertion( "contractility") SubClassOf( ) +# Class: (increased contractility) + +AnnotationAssertion(Annotation( "PATO:GVG") "A contractility which is relatively high.") +AnnotationAssertion( ) +AnnotationAssertion( "high contractility") +AnnotationAssertion( "quality") +AnnotationAssertion( "PATO:0001580") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "increased contractility") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + # Class: (curvature) AnnotationAssertion(Annotation( "WordNet:WordNet") "A surface shape quality inhering in a bearer by virtue of the bearer's exhibiting a degree of bending.") @@ -61550,6 +144178,18 @@ AnnotationAssertion( "curvature") SubClassOf( ) +# Class: (increased curvature) + +AnnotationAssertion(Annotation( "PATO:GVG") "A curvature which is relatively high.") +AnnotationAssertion( ) +AnnotationAssertion( "quality") +AnnotationAssertion( "PATO:0001592") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "increased curvature") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + # Class: (arched) AnnotationAssertion(Annotation( "WordNet:WordNet") "A concave quality inhering in a bearer by virtue of the bearer's forming or resembling an arch.") @@ -61583,6 +144223,20 @@ AnnotationAssertion(rdfs:comment " AnnotationAssertion(rdfs:label "contractile") SubClassOf( ) +# Class: (increased viscosity) + +AnnotationAssertion(Annotation( "PATOC:GVG") "A viscosity which relatively high.") +AnnotationAssertion( ) +AnnotationAssertion( "high viscosity") +AnnotationAssertion( "quality") +AnnotationAssertion( "PATO:0001693") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "increased viscosity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + # Class: (liquid configuration) AnnotationAssertion(Annotation( "PATOC:GVG") "A physical quality inhering in a bearer by virtue of the bearer's parts having the arrangement which exhibits characteristics of liquids.") @@ -61613,6 +144267,20 @@ AnnotationAssertion( "invaginated") SubClassOf( ) +# Class: (increased flexibility) + +AnnotationAssertion(Annotation( "PATOC:GVG") "A flexibility which is relatively high.") +AnnotationAssertion( ) +AnnotationAssertion( "high flexibility") +AnnotationAssertion( "quality") +AnnotationAssertion( "PATO:0001776") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "increased flexibility") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + # Class: (coiling) AnnotationAssertion(Annotation( "Online_Dictionary:Online_Dictionary") "A shape quality inhering in a bearer by virtue of the bearer's being wound in a continuous series of loops.") @@ -61622,6 +144290,20 @@ AnnotationAssertion( "coiling") SubClassOf( ) +# Class: (increased coiling) + +AnnotationAssertion(Annotation( "PATOC:GVG") "A coiling which is relatively high.") +AnnotationAssertion( ) +AnnotationAssertion( "high coiling") +AnnotationAssertion( "quality") +AnnotationAssertion( "PATO:0001795") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "increased coiling") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + # Class: (acidity) AnnotationAssertion(Annotation( "biology-online:biology-online") "A concentration quality inhering in a bearer by virtue of the bearer's containing acid (hydrogen ions).") @@ -61633,6 +144315,19 @@ AnnotationAssertion( "acidity") SubClassOf( ) +# Class: (increased acidity) + +AnnotationAssertion(Annotation( "PATOC:GVG") "An acidity which is relatively high.") +AnnotationAssertion( ) +AnnotationAssertion( "high acidity") +AnnotationAssertion( "quality") +AnnotationAssertion( "PATO:0001844") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "increased acidity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + # Class: (vertical) AnnotationAssertion(Annotation( "thefreedictionary.com:thefreedictionary.com") "A spatial pattern inhering in a bearer by virtue of the bearer's being situated at right angles to the horizon.") @@ -61692,6 +144387,16 @@ AnnotationAssertion(rdfs:label "tr SubClassOf( ) SubClassOf( ) +# Class: (multinucleate) + +AnnotationAssertion(Annotation( "PATOC:GVG") "A nucleate quality inhering in a bearer by virtue of the bearer's having more than one nucleus.") +AnnotationAssertion( "quality") +AnnotationAssertion( "PATO:0001908") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "multinucleate") +SubClassOf( ) + # Class: (folded) AnnotationAssertion(Annotation( "PATOC:cjm") "A surface feature shape quality inhering in a bearer by virtue of the bearer's one part being layered over another connected part.") @@ -61832,6 +144537,16 @@ AnnotationAssertion( "structure, cavities") SubClassOf( ) +# Class: (biconcave) + +AnnotationAssertion(Annotation( "PATOC:GVG") "A concave quality inhering in a bearer by virtue of the bearer's curving inward on both sides or surfaces.") +AnnotationAssertion( ) +AnnotationAssertion( "quality") +AnnotationAssertion( "PATO:0002039") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "biconcave") +SubClassOf( ) + # Class: (dendritic) AnnotationAssertion(Annotation( "PATOC:cvs") "A branched quality inhering in a bearer by virtue of the bearer's having smaller branches arising from larger branches. Resembling a tree in branching structure.") @@ -61846,6 +144561,20 @@ AnnotationAssertion( "dendritic") SubClassOf( ) +# Class: (increased occurrence) + +AnnotationAssertion(Annotation( "PATOC:GVG") "An occurrence which is relatively high.") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( "2009-03-26T11:10:11Z") +AnnotationAssertion( "increased incidence") +AnnotationAssertion( "quality") +AnnotationAssertion( "PATO:0002051") +AnnotationAssertion(rdfs:label "increased occurrence") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + # Class: (physical quality of a process) AnnotationAssertion( ) @@ -61867,6 +144596,19 @@ AnnotationAssertion( "hollow") SubClassOf( ) +# Class: (basophilic) + +AnnotationAssertion(Annotation( "PATOC:GVG") "An affinity inhering in an anatomical structure by virtue of the bearer exhibiting a molecular interaction for basic dyes under specific pH conditions.") +AnnotationAssertion( ) +AnnotationAssertion( "2009-10-05T12:05:23Z") +AnnotationAssertion( "quality") +AnnotationAssertion( "PATO:0002094") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "basophilic") +SubClassOf( ) + # Class: (laminar) AnnotationAssertion(Annotation( "PATOC:GVG") "A quality inhering in a bearer by virtue of the bearer's processing the form of a thin plate sheet or layer.") @@ -61879,6 +144621,19 @@ AnnotationAssertion( "laminar") SubClassOf( ) +# Class: (high-arched) + +AnnotationAssertion(Annotation( "PATOC:GVG") "A concave quality inhering in a bearer by virtue of the bearer's forming or resembling an arch of an increased apical height.") +AnnotationAssertion( ) +AnnotationAssertion( "2009-11-26T02:34:06Z") +AnnotationAssertion( "quality") +AnnotationAssertion( "PATO:0002162") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "high-arched") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + # Class: (molecular quality) AnnotationAssertion(Annotation( "PATOC:GVG") "A quality which inheres in a molecular entity, a single molecule, atom, ion, radical etc.") @@ -61961,6 +144716,20 @@ AnnotationAssertion( "3-D shape") SubClassOf( ) +# Class: (increased elasticity) + +AnnotationAssertion(Annotation( "PATOC:GVG") "An elasticity which is relatively high.") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( "2011-03-30T11:50:21Z") +AnnotationAssertion( "quality") +AnnotationAssertion( "PATO:0002287") +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "increased elasticity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + # Class: (tubular) AnnotationAssertion(Annotation( "PATOC:GVG") "A cylindrical shape that is hollow.") @@ -61975,6 +144744,44 @@ AnnotationAssertion(rdfs:label "tu SubClassOf( ) SubClassOf( ) +# Class: (increased quality) + +AnnotationAssertion(Annotation( "PATOC:GVG") "A quality that has a value that is increased compared to normal or average.") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( "2011-06-16T06:39:43Z") +AnnotationAssertion( "quality") +AnnotationAssertion( "PATO:0002300") +AnnotationAssertion(rdfs:label "increased quality") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) + +# Class: (increased process quality) + +AnnotationAssertion(Annotation( "PATOC:GVG") "A quality of a process that has a value that is increased compared to normal or average.") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( "2011-06-16T06:53:08Z") +AnnotationAssertion( "quality") +AnnotationAssertion( "PATO:0002304") +AnnotationAssertion(rdfs:label "increased process quality") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + +# Class: (increased object quality) + +AnnotationAssertion(Annotation( "PATOC:GVG") "A quality of an object that has a value that is increased compared to normal or average.") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( "2011-06-16T06:54:01Z") +AnnotationAssertion( "quality") +AnnotationAssertion( "PATO:0002305") +AnnotationAssertion(rdfs:label "increased object quality") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) + # Class: (fiber shaped) AnnotationAssertion(Annotation( "PATOC:DC") "A convex 3-D shape quality inhering in a bearer by virtue of the bearer's exhibiting a by virtue of the bearer's exhibiting a consistently sized and approximately round cross-section along its length, which is many times larger than its diameter.") @@ -62021,6 +144828,20 @@ AnnotationAssertion( "ridged") SubClassOf( ) +# Class: (acidophilic) + +AnnotationAssertion(Annotation( "PATOC:GVG") "An affinity inhering in an anatomical structure by virtue of the bearer exhibiting a molecular interaction for acidic dyes under specific pH conditions.") +AnnotationAssertion( ) +AnnotationAssertion( "2012-12-17T03:01:19Z") +AnnotationAssertion( "eosinophilic") +AnnotationAssertion( "quality") +AnnotationAssertion( "PATO:0002418") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:comment "Eosin stains acidophilic structures, hence eosinophilic is the same as acidophilic.") +AnnotationAssertion(rdfs:label "acidophilic") +SubClassOf( ) + # Class: (acinar) AnnotationAssertion(Annotation( "wikipedia:https://en.wikipedia.org/wiki/Acinus") "Pertaining to the individual parts making up an aggregate fruit like a many-lobed \"berry,\" such as a raspberry.") @@ -62067,6 +144888,44 @@ AnnotationAssertion( "distensible") SubClassOf( ) +# Class: (transversely striated) + +AnnotationAssertion(Annotation( "PATOC:DS") "A shape quality inhering in a bearer by virtue of the bearer's being marked by narrow lines or grooves, usually parallel, that are oriented transversely relative to the long axis of the bearer.") +AnnotationAssertion( ) +AnnotationAssertion( "2013-09-15T12:29:15Z") +AnnotationAssertion( "quality") +AnnotationAssertion( "PATO:0002478") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "transversely striated") +SubClassOf( ) + +# Class: (obliquely striated) + +AnnotationAssertion(Annotation( "PATOC:DS") "A shape quality inhering in a bearer by virtue of the bearer's being marked by narrow lines or grooves, usually parallel, that are oriented obliquely relative to the long axis of the bearer.") +AnnotationAssertion( ) +AnnotationAssertion( "2013-09-15T12:29:42Z") +AnnotationAssertion( "quality") +AnnotationAssertion( "PATO:0002479") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "obliquely striated") +SubClassOf( ) + +# Class: (nucleated) + +AnnotationAssertion(Annotation( "PATOC:GVG") "A nucleate quality inhering in a bearer by virtue of the bearer's having one or more nucleus.") +AnnotationAssertion( ) +AnnotationAssertion( "2013-10-21T05:44:34Z") +AnnotationAssertion( "quality") +AnnotationAssertion( "PATO:0002505") +AnnotationAssertion( ) +AnnotationAssertion( ) +AnnotationAssertion(rdfs:label "nucleated") +SubClassOf( ) + # Class: (keratinous) AnnotationAssertion(Annotation( "PATOC:EJS") "A composition quality inhering in a bearer by virtue of the bearer's consisting of keratin.") @@ -62121,6 +144980,17 @@ AnnotationAssertion( "disconnected") SubClassOf( ) +# Class: (cell morphology) + +AnnotationAssertion(Annotation( "ORCID:0000-0002-7073-9172") "A quality of a single cell inhering in the bearer by virtue of the bearer's size or shape or structure.") +AnnotationAssertion( ) +AnnotationAssertion( "2021-01-23T11:31:53Z") +AnnotationAssertion( "quality") +AnnotationAssertion( "PATO:0010006") +AnnotationAssertion(rdfs:comment "Use this term for morphologies that can *only* inhere in a cell, e.g. morphological qualities inhering in a cell by virtue of the presence, location or shape of one or more cell parts.") +AnnotationAssertion(rdfs:label "cell morphology") +SubClassOf( ) + # Class: (polymeric) AnnotationAssertion(Annotation( "GOC:DOS") Annotation( "https://github.com/pato-ontology/pato/issues/78") "A quality inhering in a structure by virtue of it consisting of many of repeated, similar or identical subunits, arranged in some orderly array.") @@ -62140,6 +145010,74 @@ AnnotationAssertion( "distensibility") SubClassOf( ) +# Class: (basket cell morphology) + +AnnotationAssertion(Annotation( "WikipediaVersioned:Basket_cell&oldid=951703880") Annotation( "doi:10.1016/b978-0-12-369497-3.10004-4") "A cell morphology that inheres in multipolar neurons with densely branched terminal axonal arborizations that form basket-like structures surrounding and synapsing to the somas of target cells.") +AnnotationAssertion( ) +AnnotationAssertion( "ILX:0101123") +AnnotationAssertion( "ilxtr:BasketPhenotype") +AnnotationAssertion( "nifext:3") +AnnotationAssertion( "quality") +AnnotationAssertion( "PATO:0070002") +AnnotationAssertion(rdfs:label "basket cell morphology") +SubClassOf( ) + +# Class: (cortical bipolar morphology) + +AnnotationAssertion(Annotation( "PMID:18568015") Annotation( "doi:10.1016/b978-0-12-369497-3.10004-4") "A cell morphology that inheres in neurons which have two principal dendrites that emerge from the soma and begin to branch some distance from it, have few spines, and branch in narrow fields. This is in contrast to bitufted morphology where branching occurs close to the soma.") +AnnotationAssertion( ) +AnnotationAssertion( "ILX:0101312") +AnnotationAssertion( "ilxtr:BipolarPhenotype") +AnnotationAssertion( "nifext:2") +AnnotationAssertion( "quality") +AnnotationAssertion( "PATO:0070006") +AnnotationAssertion(rdfs:comment "This is specific to cortical bipolar cells and are distinguished from retinal bipolar cell morphology which has an axon and dendrite emerging from opposite ends of the soma.") +AnnotationAssertion(rdfs:label "cortical bipolar morphology") +SubClassOf( ) + +# Class: (stellate morphology) + +AnnotationAssertion(Annotation( "ISBN:9780123973481") "A cell morphology that inheres in neurons that have dendritic processes radiating from the cell body forming a star-like shape.") +AnnotationAssertion( ) +AnnotationAssertion( "ILX:0111036") +AnnotationAssertion( "SAO:9271919883") +AnnotationAssertion( "quality") +AnnotationAssertion( "PATO:0070010") +AnnotationAssertion(rdfs:label "stellate morphology") +SubClassOf( ) + +# Class: (pyramidal family morphology) + +AnnotationAssertion(Annotation( "doi:10.1016/b978-0-12-369497-3.10004-4") "A cell morphology that inheres in neurons which have a pyramidal shaped soma, a single axon, a large apical dendrite and multiple basal dendrites.") +AnnotationAssertion( ) +AnnotationAssertion( "ILX:0109553") +AnnotationAssertion( "SAO:1465673360") +AnnotationAssertion( "quality") +AnnotationAssertion( "PATO:0070015") +AnnotationAssertion(rdfs:label "pyramidal family morphology") +SubClassOf( ) + +# Class: (multipolar neuron morphology) + +AnnotationAssertion(Annotation( "WikipediaVersioned:Multipolar_neuron&oldid=1022942606") "A cell morphology that inheres in neurons which possess three or more neurites, usually a single axon and many dendrites and dendritic branches.") +AnnotationAssertion( ) +AnnotationAssertion( "ILX:0107196") +AnnotationAssertion( "NLX:378") +AnnotationAssertion( "quality") +AnnotationAssertion( "PATO:0070026") +AnnotationAssertion(rdfs:label "multipolar neuron morphology") +SubClassOf( ) + +# Class: (bitufted dendrite cell morphology) + +AnnotationAssertion(Annotation( "PMID:18568015") "A cell morphology that inheres in neurons with dendrites that are bidirectional, emerging from opposite ends of the soma, with the two arbors extending in radial or tangential directions.") +AnnotationAssertion( ) +AnnotationAssertion( "quality") +AnnotationAssertion( "PATO:0070027") +AnnotationAssertion(rdfs:comment "This morphology type is distinct from bitufted cell morphology in that it refers to bitufted dendrite morphology rather than bitufted cell morphology.") +AnnotationAssertion(rdfs:label "bitufted dendrite cell morphology") +SubClassOf( ) + # Class: (anatomical structure quality) AnnotationAssertion( "A quality of continuant that exist at the anatomical level of organisation and anything under it. This includes, but is not limited to, cells , tissues, and components.") @@ -62149,6 +145087,33 @@ AnnotationAssertion( "anatomical structure quality") SubClassOf( ) +# Class: (anatomical histological quality) + +AnnotationAssertion( "A quality inhering in an anotomical structure by virtue of its capacity to be stained by specific histological dyes.") +AnnotationAssertion( "http://orcid.org/0000-0001-7258-9596") +AnnotationAssertion( "quality") +AnnotationAssertion( "PATO:0070045") +AnnotationAssertion(rdfs:label "anatomical histological quality") +SubClassOf( ) + +# Class: (neutrophillic) + +AnnotationAssertion(Annotation( "GOC:add") "An affinity inhering in an anatomical structure by virtue of the bearer exhibiting a molecular interaction that stains and colors, pale-pink, with Wright-Giemsa stain.") +AnnotationAssertion( "http://orcid.org/0000-0001-7258-9596") +AnnotationAssertion( "quality") +AnnotationAssertion( "PATO:0070046") +AnnotationAssertion(rdfs:label "neutrophillic") +SubClassOf( ) + +# Class: (polychromatophilic) + +AnnotationAssertion(Annotation( "GOC:add") "An affinity inhering in an anatomical structure by virtue of the bearer exhibiting a molecular interaction for both basic and acid stains under specific pH conditions.") +AnnotationAssertion( "http://orcid.org/0000-0001-7258-9596") +AnnotationAssertion( "quality") +AnnotationAssertion( "PATO:0070047") +AnnotationAssertion(rdfs:label "polychromatophilic") +SubClassOf( ) + # Class: (quality of interaction of a substance with electromagnetic radiation) AnnotationAssertion(Annotation( "https://orcid.org/0000-0002-5111-7263") "A quality of a substance on which or through which electromagnetic radiation impinges or traverses with respect to radiation. This substance quality changes the quality of the incident radiation with respect to any of: intensity, direction, scatter and wavelength.") @@ -62167,12 +145132,1472 @@ AnnotationAssertion( "PR:000000001") AnnotationAssertion(rdfs:comment "The definition above excludes protein complexes, which some also consider a protein. Those who wish to refer to a class representing both senses of the word are directed to CHEBI:36080. Note that the definition allows for experimentally-manipulated genes, and allows for artifically-produced derivatives that mimic those found naturally. Proteins (in the sense defined here) that descended from a common ancestor can be classified into families and superfamilies composed of products of evolutionarily-related genes. The domain architecture of a protein is described by the order of its constituent domains. Proteins with the same domains in the same order are defined as homeomorphic [PRO:WCB].") AnnotationAssertion(rdfs:label "protein") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (CD19 molecule) + +AnnotationAssertion(Annotation( "PMID:15778510") "A protein that is a translation product of the human CD19 gene or a 1:1 ortholog thereof. It is composed of an N-terminal extracellular domain containing two Ig-like C2-type (immunoglobulin-like) domains, followed by a single-pass transmembrane segment and a cytoplasmic C-terminal tail. CD19 expression is restricted to members of the B cell lineage. It functions as a co-receptor for B-cell antigen receptor (BCR), regulating signal transduction.") +AnnotationAssertion( "IUPHARobj:2764") +AnnotationAssertion( "PIRSF:PIRSF016630") +AnnotationAssertion( "B-lymphocyte surface antigen B4") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "CD19") +AnnotationAssertion( "T-cell surface antigen Leu-12") +AnnotationAssertion( "differentiation antigen CD19") +AnnotationAssertion( "protein") +AnnotationAssertion( "PR:000001002") +AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") +AnnotationAssertion(rdfs:label "CD19 molecule") +SubClassOf( ) + +# Class: (CD34 molecule) + +AnnotationAssertion(Annotation( "PMID:16720896") Annotation( "PMID:8983065") "A protein that is a translation product of the human CD34 gene or a 1:1 ortholog thereof. It is a leukocyte membrane protein expressed specifically by lymphohematopoietic progenitor cells. It contains a single-pass transmembrane domain and that show distinct expression on early hematopoietic precursors and vascular-associated tissue. Acts as a scaffold that presents selectin carbohydrate ligands in a clustered, tissue specific manner to allow for higher avidity interactions between leukocytes and endothelial cells during the inflammatory process. In common with related sialomucins (endoglycan and podocalyxin), the extracellular region is dominated by an N-terminal mucin-like domain, which is densely substituted with sialylated O-linked carbohydrates. The mucin-like region is followed by a cysteine-containing and presumably globular domain. This domain may fold into an immunoglobulin-like structure as the positions of 2 of the cysteines are conserved in the C2 set of the immunoglobulin superfamily. The cytoplasmic domain is around 73-76 residues long and highly conserved.") +AnnotationAssertion( "PIRSF:PIRSF028749") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "CD34") +AnnotationAssertion( "hematopoietic progenitor cell antigen CD34") +AnnotationAssertion( "protein") +AnnotationAssertion( "PR:000001003") +AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") +AnnotationAssertion(rdfs:label "CD34 molecule") +SubClassOf( ) + +# Class: (CD4 molecule) + +AnnotationAssertion(Annotation( "PMID:15326605") "A protein that is a translation product of the human CD4 gene or a 1:1 ortholog thereof. CD4 is an accessory protein for MHC class-II antigen/T-cell receptor interaction. It is the primary receptor for HIV-1. CD4 has four immunoglobulin-like domains in its extracellular region that share the same structure, but can differ in sequence.") +AnnotationAssertion( "PIRSF:PIRSF001977") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "CD4") +AnnotationAssertion( "T-cell differentiation antigen L3T4") +AnnotationAssertion( "T-cell surface antigen T4/Leu-3") +AnnotationAssertion( "T-cell surface glycoprotein CD4") +AnnotationAssertion( "protein") +AnnotationAssertion( "PR:000001004") +AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") +AnnotationAssertion(rdfs:label "CD4 molecule") +SubClassOf( ) + +# Class: (integrin alpha with A domain) + +AnnotationAssertion(Annotation( "PIRSF:PIRSF002497") "An integrin alpha that contains an A domain. A hallmark of this class is the presence of a von Willebrand factor type A domain (Pfam:PF00092) (I-domain) of approximately 200 amino acid residues at the N terminus, which confers divalent cation binding properties. Unlike other integrin alpha proteins, they do not undergo proteolytic cleavage.") +AnnotationAssertion( "PIRSF:PIRSF002497") +AnnotationAssertion( "integrin alpha with I domain") +AnnotationAssertion( "protein") +AnnotationAssertion( "PR:000001005") +AnnotationAssertion(rdfs:comment "Category=family.") +AnnotationAssertion(rdfs:label "integrin alpha with A domain") +SubClassOf( ) + +# Class: (receptor-type tyrosine-protein phosphatase C) + +AnnotationAssertion(Annotation( "PMID:1351092") Annotation( "PRO:CNA") "A protein that is a translation product of the human PTPRC gene or a 1:1 ortholog thereof. It is composed of an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic protein-tyrosine phosphatase domains. Contains 1 to 3 copies of the Fibronectin type III domain (Pfam:PF00041) followed by two copies of the Protein-tyrosine phosphatase (Pfam:PF00102) domain. Receptor-type tyrosine-protein phosphatase C (CD45) regulates signal transduction and lymphocyte activation by specific association with receptor molecules on T and B cells. Multiple isoforms of CD45 (180-235 kDa) can be generated asa result of alternative splicing of three variable exons 4(A), 5(B) and 6(C), encoding sequences at the N-terminal extracellular domain of the molecule.") +AnnotationAssertion(Annotation( "PRO:DNx") "T200") +AnnotationAssertion( "IUPHARobj:1852") +AnnotationAssertion( "PIRSF:PIRSF002004") +AnnotationAssertion( "L-CA") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "PTPRC") +AnnotationAssertion( "leukocyte common antigen") +AnnotationAssertion( "ly-5") +AnnotationAssertion( "lymphocyte antigen 5") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( ) "CD45") +AnnotationAssertion( "PR:000001006") +AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") +AnnotationAssertion(rdfs:label "receptor-type tyrosine-protein phosphatase C") +AnnotationAssertion( ) +SubClassOf( ) + +# Class: (integrin alpha-M) + +AnnotationAssertion(Annotation( "UniProtKB:P11215") "An integrin alpha with A domain that is a translation product of the human ITGAM gene or a 1:1 ortholog thereof. They constitute subunits of the integrin alpha-M/beta-2 receptor. This receptor is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is also a receptor for fibrinogen, factor X and ICAM1.") +AnnotationAssertion( "IUPHARobj:2452") +AnnotationAssertion( "CD11 antigen-like family member B") +AnnotationAssertion( "CD11b") +AnnotationAssertion( "CR-3 alpha chain") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "ITGAM") +AnnotationAssertion( "cell surface glycoprotein MAC-1 subunit alpha") +AnnotationAssertion( "leukocyte adhesion receptor MO1") +AnnotationAssertion( "neutrophil adherence receptor") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( ) "CD11B") +AnnotationAssertion(Annotation( ) "CR3A") +AnnotationAssertion( "PR:000001012") +AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") +AnnotationAssertion(rdfs:label "integrin alpha-M") +AnnotationAssertion( ) +SubClassOf( ) + +# Class: (integrin alpha-X) + +AnnotationAssertion(Annotation( "UniProtKB:P20702") "An integrin alpha with A domain that is a translation product of the human ITGAX gene or a 1:1 ortholog thereof. Integrin alpha-X complexed with beta-2 is a receptor for fibrinogen. It recognizes the sequence GPR in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis.") +AnnotationAssertion( "IUPHARobj:2454") +AnnotationAssertion( "CD11 antigen-like family member C") +AnnotationAssertion( "CD11c") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "ITGAX") +AnnotationAssertion( "Leu M5") +AnnotationAssertion( "leukocyte adhesion glycoprotein p150,95 alpha chain") +AnnotationAssertion( "leukocyte adhesion receptor p150,95") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( ) "CD11C") +AnnotationAssertion( "PR:000001013") +AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") +AnnotationAssertion(rdfs:label "integrin alpha-X") +AnnotationAssertion( ) +SubClassOf( ) + +# Class: (receptor-type tyrosine-protein phosphatase C isoform CD45RABC) + +AnnotationAssertion(Annotation( "PMID:1351092") Annotation( "PRO:CNA") Annotation( "PRO:DAN") "A receptor-type tyrosine-protein phosphatase C that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P08575-3 or a 1:1 ortholog thereof.") +AnnotationAssertion( "CD45RABC") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "PTPRC/iso:CD45RABC") +AnnotationAssertion( "protein") +AnnotationAssertion( "B220") +AnnotationAssertion( "CD45R") +AnnotationAssertion( "PR:000001014") +AnnotationAssertion(rdfs:comment "Category=sequence. Requested by=CL. Note: This isoform includes the region encoded by the variable exons 4(A), 5(B), and 6(C).") +AnnotationAssertion(rdfs:label "receptor-type tyrosine-protein phosphatase C isoform CD45RABC") +AnnotationAssertion( ) +SubClassOf( ) + +# Class: (receptor-type tyrosine-protein phosphatase C isoform CD45RA) + +AnnotationAssertion(Annotation( "PMID:1351092") Annotation( "PRO:CNA") Annotation( "PRO:DAN") "A receptor-type tyrosine-protein phosphatase C isoform CD45R that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P08575-8 or a 1:1 ortholog thereof.") +AnnotationAssertion( "CD45RA") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "PTPRC/iso:CD45RA") +AnnotationAssertion( "protein") +AnnotationAssertion( "PR:000001015") +AnnotationAssertion(rdfs:comment "Category=sequence. Requested by=CL. Note: This isoform includes the region encoded by the variable exon 4(A), and lacks the region encoded by exons 5(B) and 6(C).") +AnnotationAssertion(rdfs:label "receptor-type tyrosine-protein phosphatase C isoform CD45RA") +AnnotationAssertion( ) +SubClassOf( ) + +# Class: (CD3 subunit with immunoglobulin domain) + +AnnotationAssertion(Annotation( "PMID:16473826") Annotation( "PMID:1724736") "A protein that has a core domain composition consisting of an extracellular N-terminal domain that adopts an immunoglobulin fold, a transmembrane domain, and an intracellular C-terminal domain with a single copy of the Immunoreceptor tyrosine-based activation motif (Pfam:PF02189) (ITAM). It constitutes the invariant subunit of the T cell antigen receptor (TCR). TCR is a surface receptor on T cells responsible for recognizing MHC-restricted antigens and initiating the cellular immune response.") +AnnotationAssertion( "PIRSF:PIRSF001993") +AnnotationAssertion( "CD3 subunit with Ig-like domain") +AnnotationAssertion( "protein") +AnnotationAssertion( "PR:000001018") +AnnotationAssertion(rdfs:comment "Category=family.") +AnnotationAssertion(rdfs:label "CD3 subunit with immunoglobulin domain") +SubClassOf( ) + +# Class: (CD3 epsilon) + +AnnotationAssertion(Annotation( "PRO:CNA") "A CD3 subunit with immunoglobulin domain that is a translation product of the human CD3E gene or a 1:1 ortholog thereof.") +AnnotationAssertion( "IUPHARobj:2742") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "CD3E") +AnnotationAssertion( "CD3e") +AnnotationAssertion( "T-cell surface antigen T3/Leu-4 epsilon chain") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( ) "T3E") +AnnotationAssertion( "PR:000001020") +AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") +AnnotationAssertion(rdfs:label "CD3 epsilon") +SubClassOf( ) + +# Class: (neural cell adhesion molecule) + +AnnotationAssertion(Annotation( "PRO:CNA") "A protein with a domain composition consisting of a large extracellular domain, including five Ig-like C2-type domains followed by two copies of the Fibronectin type-III domain (Pfam:PF00041), a single-pass transmembrane domain and a short cytoplasmic C-terminal domain.") +AnnotationAssertion( "PIRSF:PIRSF002507") +AnnotationAssertion( "protein") +AnnotationAssertion( "PR:000001022") +AnnotationAssertion(rdfs:comment "Category=family.") +AnnotationAssertion(rdfs:label "neural cell adhesion molecule") +SubClassOf( ) + +# Class: (neural cell adhesion molecule NCAM) + +AnnotationAssertion(Annotation( "PMID:17975827") "A neural cell adhesion molecule that is involved in neuronal development, synaptic plasticity, and regeneration.") +AnnotationAssertion( "PIRSF:PIRSF501037") +AnnotationAssertion( "protein") +AnnotationAssertion( "PR:000001023") +AnnotationAssertion(rdfs:comment "Category=family.") +AnnotationAssertion(rdfs:label "neural cell adhesion molecule NCAM") +SubClassOf( ) + +# Class: (neural cell adhesion molecule 1) + +AnnotationAssertion(Annotation( "PRO:CNA") "A neural cell adhesion molecule NCAM that is a translation product of the human NCAM1 gene or a 1:1 ortholog thereof.") +AnnotationAssertion( "IUPHARobj:2769") +AnnotationAssertion( "CD56") +AnnotationAssertion( "N-CAM-1") +AnnotationAssertion( "NCAM-1") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "NCAM1") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( ) "NCAM") +AnnotationAssertion( "PR:000001024") +AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") +AnnotationAssertion(rdfs:label "neural cell adhesion molecule 1") +AnnotationAssertion( ) +SubClassOf( ) + +# Class: (CD2 molecule) + +AnnotationAssertion(Annotation( "PRO:CNA") "A protein that is a translation product of the human CD2 gene or a 1:1 ortholog thereof.") +AnnotationAssertion( "IUPHARobj:2600") +AnnotationAssertion( "PIRSF:PIRSF001984") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "CD2") +AnnotationAssertion( "LFA-2") +AnnotationAssertion( "LFA-3 receptor") +AnnotationAssertion( "T-cell surface antigen CD2") +AnnotationAssertion( "T-cell surface antigen T11/Leu-5") +AnnotationAssertion( "T-cell surface glycoprotein CD2") +AnnotationAssertion( "erythrocyte receptor") +AnnotationAssertion( "ly-37") +AnnotationAssertion( "lymphocyte antigen 37") +AnnotationAssertion( "rosette receptor") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( ) "SRBC") +AnnotationAssertion( "PR:000001083") +AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") +AnnotationAssertion(rdfs:label "CD2 molecule") +SubClassOf( ) + +# Class: (T-cell surface glycoprotein CD8 alpha chain) + +AnnotationAssertion(Annotation( "PMID:11114424") Annotation( "PRO:CNA") Annotation( "Wikipedia:CD8") "A protein that is a translation product of the human CD8A gene or a 1:1 ortholog thereof. CD8 is a transmembrane that is a co-receptor for MHC class-I antigen/T-cell receptor interaction. The most common form of CD8 is composed of a CD8 alpha and a CD8 beta chain.") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "CD8A") +AnnotationAssertion( "CD8a") +AnnotationAssertion( "T-cell surface glycoprotein Lyt-2") +AnnotationAssertion( "T-lymphocyte differentiation antigen T8/Leu-2") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( ) "Lyt-2") +AnnotationAssertion(Annotation( ) "Lyt2") +AnnotationAssertion(Annotation( ) "MAL") +AnnotationAssertion( "PR:000001084") +AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") +AnnotationAssertion(rdfs:label "T-cell surface glycoprotein CD8 alpha chain") +AnnotationAssertion( ) +SubClassOf( ) + +# Class: (rhodopsin-like G-protein coupled receptor) + +AnnotationAssertion(Annotation( "PMID:12761335") Annotation( "PRO:DAN") Annotation( "PRO:WCB") "A G-protein coupled receptor that contains the 7 transmembrane receptor (rhodopsin family) domain (Pfam:PF00001), which includes 7 transmembrane helices (TMI-TM7) with 3 intracellular loops (IL1-IL3) and 3 extracellular loops (EL1-EL3) between the helices. The amino-terminal region is extracellular and the carboxyl-terminal region is intracellular. Rhodopsin-like G-protein coupled receptors (GPCRs) are unique among the several classes of GPCRs in that most have a very short amino-terminal segment and several characteristic sequence motifs, particularly NSxxNPxxY in TM7 and D/E-R-Y/F between TM3 and loop IL2. Most bind their ligands within a cavity between the TM regions.") +AnnotationAssertion( "IUPHAR:GPCRListForward?class=A") +AnnotationAssertion( "PIRSF:PIRSF800006") +AnnotationAssertion(Annotation( "PMID:15914470") "class 1 G-protein coupled receptor") +AnnotationAssertion(Annotation( "IUPHAR:GPCRListForward?class=A") "class A G-protein coupled receptor") +AnnotationAssertion(Annotation( "PRO:DAN") Annotation( ) "fam:rhodopsin") +AnnotationAssertion( "protein") +AnnotationAssertion( "PR:000001094") +AnnotationAssertion(rdfs:comment "Category=family. Classification based on GRAFS system. [PMID:12761335]") +AnnotationAssertion(rdfs:label "rhodopsin-like G-protein coupled receptor") +SubClassOf( ) + +# Class: (chemokine receptor) + +AnnotationAssertion(Annotation( "PMID:12037138") Annotation( "PRO:WCB") Annotation( "PRO:XQ") "A rhodopsin-like G-protein coupled receptor that in active form binds to one or more chemokines.") +AnnotationAssertion( "IUPHARfam:14") +AnnotationAssertion( "PIRSF:PIRSF038545") +AnnotationAssertion( "protein") +AnnotationAssertion( "PR:000001128") +AnnotationAssertion(rdfs:comment "Category=family. Note: Only those that have been unequivocally shown to activate a G-protein coupled signaling pathway appear on the official IUPHAR list.") +AnnotationAssertion(rdfs:label "chemokine receptor") +SubClassOf( ) + +# Class: (C-C chemokine receptor type 2) + +AnnotationAssertion(Annotation( "PMID:12037138") Annotation( "PRO:WCB") "A chemokine receptor that is a translation product of the human CCR2 gene or a 1:1 ortholog thereof. The preferred ligands include CCL2, CCL7, CCL8, CCL13.") +AnnotationAssertion( "IUPHARobj:59") +AnnotationAssertion( "C-C CKR-2") +AnnotationAssertion( "CC-CKR-2") +AnnotationAssertion( "CCR-2") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "CCR2") +AnnotationAssertion( "CD192") +AnnotationAssertion( "JE/FIC receptor") +AnnotationAssertion( "MCP-1 receptor") +AnnotationAssertion( "MCP-1-R") +AnnotationAssertion( "chemokine receptor CCR2") +AnnotationAssertion( "monocyte chemoattractant protein 1 receptor") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( ) "CMKBR2") +AnnotationAssertion( "PR:000001199") +AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") +AnnotationAssertion(rdfs:label "C-C chemokine receptor type 2") +AnnotationAssertion( ) +SubClassOf( ) + +# Class: (CX3C chemokine receptor 1) + +AnnotationAssertion(Annotation( "PMID:12037138") Annotation( "PRO:WCB") "A chemokine receptor that is a translation product of the human CX3CR1 gene or a 1:1 ortholog thereof. The preferred ligand is CX3CL1.") +AnnotationAssertion( "IUPHARobj:74") +AnnotationAssertion( "PIRSF:PIRSF501025") +AnnotationAssertion( "C-X3-C CKR-1") +AnnotationAssertion( "CMK-BRL-1") +AnnotationAssertion( "CMK-BRL1") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "CX3CR1") +AnnotationAssertion( "G-protein coupled receptor 13") +AnnotationAssertion( "V28") +AnnotationAssertion( "beta chemokine receptor-like 1") +AnnotationAssertion( "chemokine receptor CX3CR1") +AnnotationAssertion( "fractalkine receptor") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( ) "CMKBRL1") +AnnotationAssertion(Annotation( ) "GPR13") +AnnotationAssertion( "PR:000001206") +AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") +AnnotationAssertion(rdfs:label "CX3C chemokine receptor 1") +AnnotationAssertion( ) +SubClassOf( ) + +# Class: (ADP-ribosyl cyclase) + +AnnotationAssertion(Annotation( "PRO:WCB") "A protein that contains the ADP-ribosyl cyclase domain (Pfam:PF02267).") +AnnotationAssertion( "PIRSF:PIRSF005736") +AnnotationAssertion( "protein") +AnnotationAssertion( "PR:000001281") +AnnotationAssertion(rdfs:comment "Category=family.") +AnnotationAssertion(rdfs:label "ADP-ribosyl cyclase") +SubClassOf( ) + +# Class: (membrane-spanning 4-domains subfamily A member 1) + +AnnotationAssertion(Annotation( "PRO:WCB") "A protein that is a translation product of the human MS4A1 gene or a 1:1 ortholog thereof.") +AnnotationAssertion( "IUPHARobj:2628") +AnnotationAssertion( "PIRSF:PIRSF001995") +AnnotationAssertion( "B-cell differentiation antigen Ly-44") +AnnotationAssertion( "B-cell surface antigen CD20") +AnnotationAssertion( "B-lymphocyte antigen CD20") +AnnotationAssertion( "B-lymphocyte surface antigen B1") +AnnotationAssertion( "Bp35") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "MS4A1") +AnnotationAssertion( "leukocyte surface antigen Leu-16") +AnnotationAssertion( "lymphocyte antigen 44") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( ) "CD20") +AnnotationAssertion(Annotation( ) "Ly-44") +AnnotationAssertion(Annotation( ) "Ms4a2") +AnnotationAssertion( "PR:000001289") +AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") +AnnotationAssertion(rdfs:label "membrane-spanning 4-domains subfamily A member 1") +SubClassOf( ) + +# Class: (C-type lectin domain family 4 member K) + +AnnotationAssertion(Annotation( "PRO:WCB") "A protein that is a translation product of the human CD207 gene or a 1:1 ortholog thereof.") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "CD207") +AnnotationAssertion( "langerin") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( ) "CLEC4K") +AnnotationAssertion( "PR:000001293") +AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") +AnnotationAssertion(rdfs:label "C-type lectin domain family 4 member K") +AnnotationAssertion( ) +SubClassOf( ) + +# Class: (CD44 molecule) + +AnnotationAssertion(Annotation( "PRO:WCB") "A protein that is a translation product of the human CD44 gene or a 1:1 ortholog thereof.") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "CD44") +AnnotationAssertion( "CD44 antigen") +AnnotationAssertion( "CDw44") +AnnotationAssertion( "ECMR-III") +AnnotationAssertion( "GP90 lymphocyte homing/adhesion receptor") +AnnotationAssertion( "HUTCH-I") +AnnotationAssertion( "PGP-1") +AnnotationAssertion( "epican") +AnnotationAssertion( "extracellular matrix receptor III") +AnnotationAssertion( "heparan sulfate proteoglycan") +AnnotationAssertion( "hermes antigen") +AnnotationAssertion( "hyaluronate receptor") +AnnotationAssertion( "ly-24") +AnnotationAssertion( "lymphocyte antigen 24") +AnnotationAssertion( "phagocytic glycoprotein 1") +AnnotationAssertion( "phagocytic glycoprotein I") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( ) "LHR") +AnnotationAssertion(Annotation( ) "MDU2") +AnnotationAssertion(Annotation( ) "MDU3") +AnnotationAssertion(Annotation( ) "MIC4") +AnnotationAssertion( "PGP-I") +AnnotationAssertion( "PR:000001307") +AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") +AnnotationAssertion(rdfs:label "CD44 molecule") +SubClassOf( ) + +# Class: (CD48 molecule) + +AnnotationAssertion(Annotation( "PRO:WCB") "A protein that is a translation product of the human CD48 gene or a 1:1 ortholog thereof.") +AnnotationAssertion( "PIRSF:PIRSF001973") +AnnotationAssertion( "B-lymphocyte activation marker BLAST-1") +AnnotationAssertion( "BCM1 surface antigen") +AnnotationAssertion( "BLAST-1") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "CD48") +AnnotationAssertion( "CD48 antigen") +AnnotationAssertion( "HM48-1") +AnnotationAssertion( "MRC OX-45 surface antigen") +AnnotationAssertion( "SLAM family member 2") +AnnotationAssertion( "SLAMF2") +AnnotationAssertion( "TCT.1") +AnnotationAssertion( "leukocyte antigen MEM-102") +AnnotationAssertion( "sgp-60") +AnnotationAssertion( "signaling lymphocytic activation molecule 2") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( ) "BCM1") +AnnotationAssertion(Annotation( ) "BLAST1") +AnnotationAssertion(Annotation( ) "Bcm-1") +AnnotationAssertion( "PR:000001308") +AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") +AnnotationAssertion(rdfs:label "CD48 molecule") +SubClassOf( ) + +# Class: (cadherin) + +AnnotationAssertion(Annotation( "PRO:WCB") "A protein that has a core domain structure of signal sequence, propeptide, five Cadherin domains (Pfam:PF00028), a transmembrane region, and a Cadherin cytoplasmic region (Pfam:PF01049). Cadherins function as adhesion molecules that mediate Ca2+-dependent cell-cell adhesion in solid tissues.") +AnnotationAssertion( "PIRSF:PIRSF002504") +AnnotationAssertion( "protein") +AnnotationAssertion( "PR:000001327") +AnnotationAssertion(rdfs:comment "Category=family.") +AnnotationAssertion(rdfs:label "cadherin") +SubClassOf( ) + +# Class: (carcinoembryonic antigen-related cell adhesion molecule 8) + +AnnotationAssertion(Annotation( "PRO:CNA") "A protein that is a translation product of the human CEACAM8 gene or a 1:1 ortholog thereof.") +AnnotationAssertion( "CD66b") +AnnotationAssertion( "CD67 antigen") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "CEACAM8") +AnnotationAssertion( "carcinoembryonic antigen CGM6") +AnnotationAssertion( "non-specific cross-reacting antigen NCA-95") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( ) "CGM6") +AnnotationAssertion( "PR:000001332") +AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") +AnnotationAssertion(rdfs:label "carcinoembryonic antigen-related cell adhesion molecule 8") +AnnotationAssertion( ) +SubClassOf( ) + +# Class: (complement receptor type 2) + +AnnotationAssertion(Annotation( "PRO:WCB") "A protein that is a translation product of the human CR2 gene or a 1:1 ortholog thereof.") +AnnotationAssertion( "PIRSF:PIRSF002484") +AnnotationAssertion( "CD21") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "CR2") +AnnotationAssertion( "Cr2") +AnnotationAssertion( "EBV receptor") +AnnotationAssertion( "complement C3d receptor") +AnnotationAssertion( "epstein-Barr virus receptor") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( ) "C3DR") +AnnotationAssertion( "PR:000001338") +AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") +AnnotationAssertion(rdfs:label "complement receptor type 2") +AnnotationAssertion( ) +SubClassOf( ) + +# Class: (endoglin) + +AnnotationAssertion(Annotation( "PRO:CNA") "A protein that is a translation product of the human ENG gene or a 1:1 ortholog thereof.") +AnnotationAssertion( "IUPHARobj:2895") +AnnotationAssertion( "PIRSF:PIRSF038746") +AnnotationAssertion( "CD105") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "ENG") +AnnotationAssertion( "cell surface MJ7/18 antigen") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( ) "END") +AnnotationAssertion(Annotation( ) "Edg") +AnnotationAssertion( "PR:000001345") +AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") +AnnotationAssertion(rdfs:label "endoglin") +AnnotationAssertion( ) +SubClassOf( ) + +# Class: (glycophorin) + +AnnotationAssertion(Annotation( "InterPro:IPR001195") Annotation( "PRO:CNA") "A protein that contains an extracellular Glycophorin A domain (Pfam:PF01102), followed by a single-pass transmembrane region and a small intracellular domain. A protein that is an integral protein of the red cell membrane. Proteins in this class are responsible for the molecular basis of the blood group antigens, surface markers on the outside of the red blood cell membrane.") +AnnotationAssertion( "PIRSF:PIRSF002466") +AnnotationAssertion( "protein") +AnnotationAssertion( "PR:000001352") +AnnotationAssertion(rdfs:comment "Category=family.") +AnnotationAssertion(rdfs:label "glycophorin") +SubClassOf( ) + +# Class: (immunoglobulin gamma Fc receptor II/III/IV) + +AnnotationAssertion(Annotation( "PRO:WCB") "A protein with a core domain architecture consisting of an extracellular domain containing two copies of the Immunoglobulin domain (Pfam:PF00047), followed by a single-pass transmembrane region and a small intracellular domain. The active protein is a low affinity receptor for immunoglobulin gamma chain Fc region. Human II-a, II-b, and II-c represent a recent gene expansion and are equally related to mouse II, III, and IV. Human III-A and III-B are closely related and closer to mouse IV than to mouse III.") +AnnotationAssertion( "PIRSF:PIRSF001980") +AnnotationAssertion( "protein") +AnnotationAssertion( "PR:000001355") +AnnotationAssertion(rdfs:comment "Category=family.") +AnnotationAssertion(rdfs:label "immunoglobulin gamma Fc receptor II/III/IV") +SubClassOf( ) + +# Class: (interleukin-2 receptor subunit alpha) + +AnnotationAssertion(Annotation( "PRO:CNA") "A protein that is a translation product of the human IL2RA gene or a 1:1 ortholog thereof.") +AnnotationAssertion(Annotation( "PRO:DNx") "p55") +AnnotationAssertion( "IUPHARobj:1695") +AnnotationAssertion( "PIRSF:PIRSF001954") +AnnotationAssertion( "CD25") +AnnotationAssertion( "IL-2 receptor subunit alpha") +AnnotationAssertion( "IL-2-RA") +AnnotationAssertion( "IL-2R subunit alpha") +AnnotationAssertion( "IL2-RA") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "IL2RA") +AnnotationAssertion( "TAC antigen") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( ) "Il2r") +AnnotationAssertion( "PR:000001380") +AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") +AnnotationAssertion(rdfs:label "interleukin-2 receptor subunit alpha") +AnnotationAssertion( ) +SubClassOf( ) + +# Class: (ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1) + +AnnotationAssertion(Annotation( "PRO:WCB") "An ADP-ribosyl cyclase that is a translation product of the human CD38 gene or a 1:1 ortholog thereof.") +AnnotationAssertion( "IUPHARobj:2766") +AnnotationAssertion( "2'-phospho-ADP-ribosyl cyclase") +AnnotationAssertion( "2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase") +AnnotationAssertion( "2'-phospho-cyclic-ADP-ribose transferase") +AnnotationAssertion( "ADP-ribosyl cyclase 1") +AnnotationAssertion( "ADPRC 1") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "CD38") +AnnotationAssertion( "I-19") +AnnotationAssertion( "NIM-R5 antigen") +AnnotationAssertion( "T10") +AnnotationAssertion( "cADPr hydrolase 1") +AnnotationAssertion( "cyclic ADP-ribose hydrolase 1") +AnnotationAssertion( "protein") +AnnotationAssertion( "PR:000001408") +AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") +AnnotationAssertion(rdfs:label "ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1") +AnnotationAssertion( ) +SubClassOf( ) + +# Class: (cadherin-5) + +AnnotationAssertion(Annotation( "PRO:WCB") "A cadherin that is a translation product of the human CDH5 gene or a 1:1 ortholog thereof.") +AnnotationAssertion( "7B4 antigen") +AnnotationAssertion( "CD144") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "CDH5") +AnnotationAssertion( "VE-cadherin") +AnnotationAssertion( "vascular endothelial cadherin") +AnnotationAssertion( "protein") +AnnotationAssertion( "PR:000001444") +AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") +AnnotationAssertion(rdfs:label "cadherin-5") +AnnotationAssertion( ) +SubClassOf( ) + +# Class: (glycophorin-A) + +AnnotationAssertion(Annotation( "InterPro:IPR001195") Annotation( "PRO:CNA") "A glycophorin that is a translation product of the human GYPA gene or a 1:1 ortholog thereof. It is the major sialoglycoprotein of the erythrocyte membrane. Structurally, glycophorin A consists of an N-terminal extracellular domain, heavily glycosylated on Ser and threonine residues, followed by a transmembrane region and a C-terminal cytoplasmic domain.") +AnnotationAssertion( "CD235a") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "GYPA") +AnnotationAssertion( "MN sialoglycoprotein") +AnnotationAssertion( "PAS-2") +AnnotationAssertion( "sialoglycoprotein alpha") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( ) "GPA") +AnnotationAssertion( "PR:000001460") +AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") +AnnotationAssertion(rdfs:label "glycophorin-A") +AnnotationAssertion( ) +SubClassOf( ) + +# Class: (low affinity immunoglobulin gamma Fc region receptor II) + +AnnotationAssertion(Annotation( "PRO:CNA") "An immunoglobulin gamma Fc receptor II/III/IV that is a translation product of the mouse Fcgr2 gene or a 1:1 ortholog thereof.") +AnnotationAssertion(Annotation( "PRO:DNx") "CD32") +AnnotationAssertion( "Fc gamma receptor IIB") +AnnotationAssertion( "Fc-gamma RII") +AnnotationAssertion( "Fc-gamma-RIIB") +AnnotationAssertion( "FcRII") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "Fcgr2") +AnnotationAssertion( "IgG Fc receptor II beta") +AnnotationAssertion( "ly-17") +AnnotationAssertion( "lymphocyte antigen 17") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( ) "Fcgr2b") +AnnotationAssertion( "PR:000001479") +AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") +AnnotationAssertion(rdfs:label "low affinity immunoglobulin gamma Fc region receptor II") +SubClassOf( ) + +# Class: (low affinity immunoglobulin gamma Fc region receptor II-b) + +AnnotationAssertion(Annotation( "PRO:CNA") "An immunoglobulin gamma Fc receptor II/III/IV that is a translation product of the human FCGR2B gene or a 1:1 ortholog thereof.") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "CD32") +AnnotationAssertion(Annotation( "PRO:DNx") "CDw32") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "FCGR2B") +AnnotationAssertion( "Fc-gamma RII-b") +AnnotationAssertion( "Fc-gamma-RIIb") +AnnotationAssertion( "FcRII-b") +AnnotationAssertion( "IgG Fc receptor II-b") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( ) "FCG2") +AnnotationAssertion(Annotation( ) "IGFR2") +AnnotationAssertion( "PR:000001481") +AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") +AnnotationAssertion(rdfs:label "low affinity immunoglobulin gamma Fc region receptor II-b") +AnnotationAssertion( ) +SubClassOf( ) + +# Class: (low affinity immunoglobulin gamma Fc region receptor III) + +AnnotationAssertion(Annotation( "PRO:CNA") "An immunoglobulin gamma Fc receptor II/III/IV that is a translation product of the mouse Fcgr3 gene or a 1:1 ortholog thereof.") +AnnotationAssertion( "CD16") +AnnotationAssertion( "Fc-gamma RIII") +AnnotationAssertion( "FcRIII") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "Fcgr3") +AnnotationAssertion( "IgG Fc receptor III") +AnnotationAssertion( "protein") +AnnotationAssertion( "PR:000001483") +AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") +AnnotationAssertion(rdfs:label "low affinity immunoglobulin gamma Fc region receptor III") +SubClassOf( ) + +# Class: (transcription factor NF-kappa-B subunit) + +AnnotationAssertion(Annotation( "PRO:JAN") "A protein that has a core domain composition consisting of a Rel homology domain (RHD) (Pfam:PF00554), an IPT/TIG domain (Pfam:PF01833), six copies of the Ankyrin repeat (Pfam:PF00023), a Death domain (Pfam:PF00531) and a C-terminal PEST region.") +AnnotationAssertion( "PIRSF:PIRSF036310") +AnnotationAssertion( "protein") +AnnotationAssertion( "transcription factor NF-kappa-B") +AnnotationAssertion( "PR:000001753") +AnnotationAssertion(rdfs:comment "Category=family.") +AnnotationAssertion(rdfs:label "transcription factor NF-kappa-B subunit") +SubClassOf( ) + +# Class: (prominin) + +AnnotationAssertion(Annotation( "InterPro:IPR008795") Annotation( "PMID:11467842") "A protein with core architecture consisting of one Prominin (Pfam:PF05478) domain. The prominins are an emerging family of proteins that, among the multispan membrane proteins, display a novel topology. Mouse and human prominin and prominin-like 1 are predicted to contain five membrane spanning domains, with an N-terminal domain exposed to the extracellular space followed by four, alternating small cytoplasmic and large extracellular, loops and a cytoplasmic C-terminal domain.") +AnnotationAssertion( "PANTHER:PTHR22730") +AnnotationAssertion( "PIRSF:PIRSF017831") +AnnotationAssertion( "protein") +AnnotationAssertion( "PR:000001785") +AnnotationAssertion(rdfs:comment "Category=family.") +AnnotationAssertion(rdfs:label "prominin") +SubClassOf( ) + +# Class: (prominin-1) + +AnnotationAssertion(Annotation( "PRO:CNA") "A prominin that is a translation product of the human PROM1 gene or a 1:1 ortholog thereof.") +AnnotationAssertion( "CD133") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "PROM1") +AnnotationAssertion( "antigen AC133") +AnnotationAssertion( "antigen AC133 homolog") +AnnotationAssertion( "prominin-like protein 1") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( ) "MSTP061") +AnnotationAssertion(Annotation( ) "PROML1") +AnnotationAssertion(Annotation( ) "Prom") +AnnotationAssertion( "PR:000001786") +AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") +AnnotationAssertion(rdfs:label "prominin-1") +AnnotationAssertion( ) +SubClassOf( ) + +# Class: (CD59-like glycoprotein) + +AnnotationAssertion(Annotation( "PRO:WCB") "A protein that is a translation product of the human CD59 gene, a 1:1 ortholog thereof, or pro-orthologs thereof.") +AnnotationAssertion( "PIRSF:PIRSF038782") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "CD59-like") +AnnotationAssertion( "protein") +AnnotationAssertion( "PR:000001809") +AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL. Pro-orthology refers to, in this case, after-speciation gene duplication in the non-human species (aka 1:many orthology). This gene is present as a single copy in human and has undergone a lineage-specific duplication in mouse. CD59 antigen has a core architecture consisting of one UPAR/Ly-6 domain (Pfam:PF00021), a small domain of about 70 amino acids and containing 5 conserved disulfide bonds. It is both N- and O-glycosylated and is a GPI-anchored protein that releases soluble forms in some tissues.") +AnnotationAssertion(rdfs:label "CD59-like glycoprotein") +SubClassOf( ) + +# Class: (CSF-1/PDGF receptor-type tyrosine-protein kinase) + +AnnotationAssertion(Annotation( "PRO:WCB") "A protein with core architecture consisting of asignal sequence, 5 Ig-like domains, followed by a transmembrane sequence, followed by a Protein tyrosine kinase domain (Pfam:PF07714). However, only 1-3 of the Ig domains are detected by the Pfam HMMs in most of the sequences. Pfam:PF00047 is most common, but other members of the Ig domain clan, Pfam:PF07679 and Pfam:PF07686 can be identified instead. The fourth Ig domain lacks the disulfide-bonded cysteines.") +AnnotationAssertion( "PIRSF:PIRSF000615") +AnnotationAssertion( "protein") +AnnotationAssertion( "PR:000001810") +AnnotationAssertion(rdfs:comment "Category=family.") +AnnotationAssertion(rdfs:label "CSF-1/PDGF receptor-type tyrosine-protein kinase") +SubClassOf( ) + +# Class: (SLAM family member 1) + +AnnotationAssertion(Annotation( "PRO:WCB") "A protein that is a translation product of the human SLAMF1 gene or a 1:1 ortholog thereof.") +AnnotationAssertion( "CD150") +AnnotationAssertion( "CDw150") +AnnotationAssertion( "IPO-3") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "SLAMF1") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( ) "SLAM") +AnnotationAssertion( "PR:000001833") +AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") +AnnotationAssertion(rdfs:label "SLAM family member 1") +SubClassOf( ) + +# Class: (CD7 molecule) + +AnnotationAssertion(Annotation( "PRO:WCB") "A protein that is a translation product of the human CD7 gene or a 1:1 ortholog thereof.") +AnnotationAssertion( "PIRSF:PIRSF038791") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "CD7") +AnnotationAssertion( "GP40") +AnnotationAssertion( "T-cell antigen CD7") +AnnotationAssertion( "T-cell leukemia antigen") +AnnotationAssertion( "T-cell surface antigen Leu-9") +AnnotationAssertion( "TP41") +AnnotationAssertion( "protein") +AnnotationAssertion( "PR:000001836") +AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") +AnnotationAssertion(rdfs:label "CD7 molecule") +SubClassOf( ) + +# Class: (T-cell surface glycoprotein CD5) + +AnnotationAssertion(Annotation( "PRO:WCB") "A protein that is a translation product of the human CD5 gene or a 1:1 ortholog thereof.") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "CD5") +AnnotationAssertion( "Lyt-1") +AnnotationAssertion( "ly-1") +AnnotationAssertion( "lymphocyte antigen 1") +AnnotationAssertion( "lymphocyte antigen T1/Leu-1") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( ) "LEU1") +AnnotationAssertion( "PR:000001839") +AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") +AnnotationAssertion(rdfs:label "T-cell surface glycoprotein CD5") +AnnotationAssertion( ) +SubClassOf( ) + +# Class: (Thy-1 membrane glycoprotein) + +AnnotationAssertion(Annotation( "PRO:WCB") "A protein that is a translation product of the human THY1 gene or a 1:1 ortholog thereof.") +AnnotationAssertion( "PIRSF:PIRSF038777") +AnnotationAssertion( "CD90") +AnnotationAssertion( "CDw90") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "THY1") +AnnotationAssertion( "Thy-1 antigen") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( ) "Thy-1") +AnnotationAssertion( "PR:000001843") +AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") +AnnotationAssertion(rdfs:label "Thy-1 membrane glycoprotein") +AnnotationAssertion( ) +SubClassOf( ) + +# Class: (cathepsin K) + +AnnotationAssertion(Annotation( "PRO:DAN") Annotation( "PRO:WCB") "A cathepsin-like protease that is a translation product of the human CTSK gene or a 1:1 ortholog thereof.") +AnnotationAssertion( "IUPHARobj:2350") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "CTSK") +AnnotationAssertion( "cathepsin O2") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( ) "CTSO") +AnnotationAssertion(Annotation( ) "CTSO2") +AnnotationAssertion( "cathepsin O") +AnnotationAssertion( "cathepsin X") +AnnotationAssertion( "PR:000001850") +AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") +AnnotationAssertion(rdfs:label "cathepsin K") +AnnotationAssertion( ) +SubClassOf( ) + +# Class: (immunoglobulin iota chain) + +AnnotationAssertion(Annotation( "PRO:WCB") "A protein that is a translation product of the human VPREB1 gene or a 1:1 ortholog thereof. The gene is recently and independently duplicated in mouse and rabbit, giving rise to very closely related VPREB2 genes in those species. The protein associates with the Ig-mu chain to form a molecular complex that is expressed only on the surface of pre-B-cells.") +AnnotationAssertion( "PIRSF:PIRSF038787") +AnnotationAssertion( "CD179 antigen-like family member A") +AnnotationAssertion( "CD179a") +AnnotationAssertion( "V(pre)B protein") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "VPREB1") +AnnotationAssertion( "VpreB protein") +AnnotationAssertion( "protein VPreB1") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( ) "VPREB") +AnnotationAssertion( "PR:000001858") +AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") +AnnotationAssertion(rdfs:label "immunoglobulin iota chain") +AnnotationAssertion( ) +SubClassOf( ) + +# Class: (immunoglobulin lambda-like polypeptide 1) + +AnnotationAssertion(Annotation( "PRO:WCB") "A protein that is a translation product of the human IGLL1 gene or a 1:1 ortholog thereof.") +AnnotationAssertion( "CD179 antigen-like family member B") +AnnotationAssertion( "CD179b") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "IGLL1") +AnnotationAssertion( "Ig lambda-5") +AnnotationAssertion( "immunoglobulin omega polypeptide") +AnnotationAssertion( "immunoglobulin-related protein 14.1") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( ) "IGL1") +AnnotationAssertion( "Igl-5") +AnnotationAssertion( "PR:000001859") +AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") +AnnotationAssertion(rdfs:label "immunoglobulin lambda-like polypeptide 1") +AnnotationAssertion( ) +SubClassOf( ) + +# Class: (interleukin-3 receptor class 2 alpha chain) + +AnnotationAssertion(Annotation( "PRO:WCB") "A protein that is a translation product of the human IL3RA gene or a 1:1 ortholog thereof.") +AnnotationAssertion( "IUPHARobj:1705") +AnnotationAssertion( "CD123") +AnnotationAssertion( "IL-3 receptor subunit alpha") +AnnotationAssertion( "IL-3R subunit alpha") +AnnotationAssertion( "IL-3R-alpha") +AnnotationAssertion( "IL-3RA") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "IL3RA") +AnnotationAssertion( "interleukin-3 receptor class II alpha chain") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( ) "IL3R") +AnnotationAssertion(Annotation( ) "Sut-1") +AnnotationAssertion( "PR:000001865") +AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") +AnnotationAssertion(rdfs:label "interleukin-3 receptor class 2 alpha chain") +SubClassOf( ) + +# Class: (interleukin-5 receptor subunit alpha) + +AnnotationAssertion(Annotation( "PRO:WCB") "A protein that is a translation product of the human IL5RA gene or a 1:1 ortholog thereof.") +AnnotationAssertion( "IUPHARobj:1706") +AnnotationAssertion( "PIRSF:PIRSF018419") +AnnotationAssertion( "CD125") +AnnotationAssertion( "CDw125") +AnnotationAssertion( "IL-5 receptor subunit alpha") +AnnotationAssertion( "IL-5R subunit alpha") +AnnotationAssertion( "IL-5R-alpha") +AnnotationAssertion( "IL-5RA") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "IL5RA") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( ) "IL5R") +AnnotationAssertion( "PR:000001867") +AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") +AnnotationAssertion(rdfs:label "interleukin-5 receptor subunit alpha") +AnnotationAssertion( ) +SubClassOf( ) + +# Class: (interleukin-7 receptor subunit alpha) + +AnnotationAssertion(Annotation( "PRO:WCB") "A protein that is a translation product of the human IL7R gene or a 1:1 ortholog thereof.") +AnnotationAssertion( "IUPHARobj:1698") +AnnotationAssertion( "PIRSF:PIRSF001960") +AnnotationAssertion( "CD127") +AnnotationAssertion( "CDw127") +AnnotationAssertion( "IL-7 receptor subunit alpha") +AnnotationAssertion( "IL-7R subunit alpha") +AnnotationAssertion( "IL-7R-alpha") +AnnotationAssertion( "IL-7RA") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "IL7R") +AnnotationAssertion( "protein") +AnnotationAssertion( "PR:000001869") +AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") +AnnotationAssertion(rdfs:label "interleukin-7 receptor subunit alpha") +AnnotationAssertion( ) +SubClassOf( ) + +# Class: (KLRB1-like protein) + +AnnotationAssertion(Annotation( "PRO:WCB") "A protein that is a translation product of the KLRB1 gene or its closely related paralogs (KLRB1A-F). There are lineage-specific expansions in mouse and rat.") +AnnotationAssertion( "PIRSF:PIRSF038804") +AnnotationAssertion( "protein") +AnnotationAssertion( "PR:000001874") +AnnotationAssertion(rdfs:comment "Category=family. Requested by=CL.") +AnnotationAssertion(rdfs:label "KLRB1-like protein") +SubClassOf( ) + +# Class: (leukosialin) + +AnnotationAssertion(Annotation( "PRO:WCB") "A protein that is a translation product of the human SPN gene or a 1:1 ortholog thereof.") +AnnotationAssertion( "PIRSF:PIRSF001994") +AnnotationAssertion( "B-cell differentiation antigen LP-3") +AnnotationAssertion( "GALGP") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "SPN") +AnnotationAssertion( "galactoglycoprotein") +AnnotationAssertion( "leukocyte sialoglycoprotein") +AnnotationAssertion( "ly-48") +AnnotationAssertion( "lymphocyte antigen 48") +AnnotationAssertion( "sialophorin") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( ) "CD43") +AnnotationAssertion( "PR:000001879") +AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") +AnnotationAssertion(rdfs:label "leukosialin") +AnnotationAssertion( ) +SubClassOf( ) + +# Class: (low affinity immunoglobulin epsilon Fc receptor) + +AnnotationAssertion(Annotation( "PRO:WCB") "A protein that is a translation product of the human FCER2 gene or a 1:1 ortholog thereof.") +AnnotationAssertion( "IUPHARobj:2935") +AnnotationAssertion( "PIRSF:PIRSF002426") +AnnotationAssertion( "BLAST-2") +AnnotationAssertion( "C-type lectin domain family 4 member J") +AnnotationAssertion( "CD23") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "FCER2") +AnnotationAssertion( "Fc-epsilon-RII") +AnnotationAssertion( "immunoglobulin E-binding factor") +AnnotationAssertion( "lymphocyte IgE receptor") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( ) "CD23A") +AnnotationAssertion(Annotation( ) "CLEC4J") +AnnotationAssertion(Annotation( ) "FCE2") +AnnotationAssertion(Annotation( ) "Fcer2a") +AnnotationAssertion(Annotation( ) "IGEBF") +AnnotationAssertion( "PR:000001880") +AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") +AnnotationAssertion(rdfs:label "low affinity immunoglobulin epsilon Fc receptor") +AnnotationAssertion( ) +SubClassOf( ) + +# Class: (membrane alanyl aminopeptidase-like metallopeptidase) + +AnnotationAssertion(Annotation( "PRO:WCB") "A protein with core architecture consisting of a Peptidase family M1 domain (Pfam:PF01433).") +AnnotationAssertion( "PIRSF:PIRSF005502") +AnnotationAssertion( "protein") +AnnotationAssertion( "PR:000001888") +AnnotationAssertion(rdfs:comment "Category=family.") +AnnotationAssertion(rdfs:label "membrane alanyl aminopeptidase-like metallopeptidase") +SubClassOf( ) + +# Class: (CD14 molecule) + +AnnotationAssertion(Annotation( "PRO:WCB") "A protein that is a translation product of the human CD14 gene or a 1:1 ortholog thereof.") +AnnotationAssertion( "PIRSF:PIRSF002017") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "CD14") +AnnotationAssertion( "monocyte differentiation antigen CD14") +AnnotationAssertion( "myeloid cell-specific leucine-rich glycoprotein") +AnnotationAssertion( "protein") +AnnotationAssertion( "PR:000001889") +AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") +AnnotationAssertion(rdfs:label "CD14 molecule") +SubClassOf( ) + +# Class: (CD33 molecule) + +AnnotationAssertion(Annotation( "PRO:WCB") "A protein that is a translation product of the human CD33 gene or a 1:1 ortholog thereof.") +AnnotationAssertion( "IUPHARobj:2601") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "CD33") +AnnotationAssertion( "gp67") +AnnotationAssertion( "myeloid cell surface antigen CD33") +AnnotationAssertion( "sialic acid-binding Ig-like lectin 3") +AnnotationAssertion( "siglec-3") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( ) "SIGLEC3") +AnnotationAssertion( "PR:000001892") +AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") +AnnotationAssertion(rdfs:label "CD33 molecule") +SubClassOf( ) + +# Class: (natural killer cell receptor 2B4) + +AnnotationAssertion(Annotation( "PRO:WCB") "A protein that is a translation product of the human CD244 gene or a 1:1 ortholog thereof.") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "CD244") +AnnotationAssertion( "NAIL") +AnnotationAssertion( "NK cell activation-inducing ligand") +AnnotationAssertion( "NK cell type I receptor protein 2B4") +AnnotationAssertion( "NKR2B4") +AnnotationAssertion( "SLAM family member 4") +AnnotationAssertion( "SLAMF4") +AnnotationAssertion( "non-MHC restricted killing associated") +AnnotationAssertion( "signaling lymphocytic activation molecule 4") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( ) "2B4") +AnnotationAssertion(Annotation( ) "Nmrk") +AnnotationAssertion( "PR:000001896") +AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") +AnnotationAssertion(rdfs:label "natural killer cell receptor 2B4") +AnnotationAssertion( ) +SubClassOf( ) + +# Class: (neprilysin) + +AnnotationAssertion(Annotation( "PRO:WCB") "A protein that is a translation product of the human MME gene or a 1:1 ortholog thereof.") +AnnotationAssertion( "IUPHARobj:1611") +AnnotationAssertion( "PIRSF:PIRSF501074") +AnnotationAssertion( "CALLA") +AnnotationAssertion( "CD10") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "MME") +AnnotationAssertion( "NEP") +AnnotationAssertion( "SFE") +AnnotationAssertion( "atriopeptidase") +AnnotationAssertion( "common acute lymphocytic leukemia antigen") +AnnotationAssertion( "enkephalinase") +AnnotationAssertion( "neutral endopeptidase") +AnnotationAssertion( "neutral endopeptidase 24.11") +AnnotationAssertion( "skin fibroblast elastase") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( ) "EPN") +AnnotationAssertion( "PR:000001898") +AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") +AnnotationAssertion(rdfs:label "neprilysin") +AnnotationAssertion( ) +SubClassOf( ) + +# Class: (paired box protein PAX-5) + +AnnotationAssertion(Annotation( "PRO:WCB") "A protein that is a translation product of the human PAX5 gene or a 1:1 ortholog thereof.") +AnnotationAssertion( "B-cell-specific transcription factor") +AnnotationAssertion( "BSAP") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "PAX5") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( ) "Pax-5") +AnnotationAssertion( "PR:000001903") +AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") +AnnotationAssertion(rdfs:label "paired box protein PAX-5") +AnnotationAssertion( ) +SubClassOf( ) + +# Class: (scavenger receptor cysteine-rich type 1 protein M130) + +AnnotationAssertion(Annotation( "PRO:WCB") "A protein that is a translation product of the human CD163 gene or a 1:1 ortholog thereof.") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "CD163") +AnnotationAssertion( "hemoglobin scavenger receptor") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( ) "M130") +AnnotationAssertion( "PR:000001925") +AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") +AnnotationAssertion(rdfs:label "scavenger receptor cysteine-rich type 1 protein M130") +AnnotationAssertion( ) +SubClassOf( ) + +# Class: (signal transducer CD24) + +AnnotationAssertion(Annotation( "PRO:WCB") "A protein that is a translation product of the human CD24 gene or a 1:1 ortholog thereof.") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "CD24") +AnnotationAssertion( "HSA") +AnnotationAssertion( "M1/69-J11D heat stable antigen") +AnnotationAssertion( "R13-Ag") +AnnotationAssertion( "X62 heat stable antigen") +AnnotationAssertion( "ly-52") +AnnotationAssertion( "lymphocyte antigen 52") +AnnotationAssertion( "nectadrin") +AnnotationAssertion( "small cell lung carcinoma cluster 4 antigen") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( ) "CD24A") +AnnotationAssertion( "PR:000001932") +AnnotationAssertion(rdfs:comment "Category=gene. The mouse ortholog is Cd24a. Mouse protein Cd24b likely also orthologous. Currently it is not in UniProt. Requested by=CL.") +AnnotationAssertion(rdfs:label "signal transducer CD24") +AnnotationAssertion( ) +SubClassOf( ) + +# Class: (syndecan-1) + +AnnotationAssertion(Annotation( "PRO:WCB") "A protein that is a translation product of the human SDC1 gene or a 1:1 ortholog thereof.") +AnnotationAssertion( "PIRSF:PIRSF015854") +AnnotationAssertion( "CD138") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "SDC1") +AnnotationAssertion( "SYND1") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( ) "SDC") +AnnotationAssertion(Annotation( ) "Synd-1") +AnnotationAssertion( "PR:000001935") +AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") +AnnotationAssertion(rdfs:label "syndecan-1") +AnnotationAssertion( ) +SubClassOf( ) + +# Class: (tartrate-resistant acid phosphatase type 5) + +AnnotationAssertion(Annotation( "PRO:WCB") "A protein that is a translation product of the human ACP5 gene or a 1:1 ortholog thereof.") +AnnotationAssertion( "PIRSF:PIRSF000898") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "ACP5") +AnnotationAssertion( "TR-AP") +AnnotationAssertion( "TrATPase") +AnnotationAssertion( "tartrate-resistant acid ATPase") +AnnotationAssertion( "type 5 acid phosphatase") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( ) "T5ap") +AnnotationAssertion(Annotation( ) "Trap") +AnnotationAssertion( "PR:000001937") +AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") +AnnotationAssertion(rdfs:label "tartrate-resistant acid phosphatase type 5") +AnnotationAssertion( ) +SubClassOf( ) + +# Class: (thrombomodulin-like receptor) + +AnnotationAssertion(Annotation( "PRO:WCB") "A protein with core architecture consisting of a signal sequence, a Lectin C-type domain (Pfam:PF00059), 5 or 6 EGF-like domains (Pfam:PF00008, Pfam:PF09064, or Pfam:PF07645), a transmembrane region, and a small cytoplasmic region (36-51 amino acids).") +AnnotationAssertion( "PIRSF:PIRSF001775") +AnnotationAssertion( "protein") +AnnotationAssertion( "PR:000001938") +AnnotationAssertion(rdfs:comment "Category=family.") +AnnotationAssertion(rdfs:label "thrombomodulin-like receptor") +SubClassOf( ) + +# Class: (transcription factor PU.1) + +AnnotationAssertion(Annotation( "PRO:WCB") "A protein that is a translation product of the human SPI1 gene or a 1:1 ortholog thereof.") +AnnotationAssertion( "31 kDa-transforming protein") +AnnotationAssertion( "SFFV proviral integration 1 protein") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "SPI1") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( ) "Sfpi-1") +AnnotationAssertion(Annotation( ) "Sfpi1") +AnnotationAssertion( "PR:000001944") +AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") +AnnotationAssertion(rdfs:label "transcription factor PU.1") +AnnotationAssertion( ) +SubClassOf( ) + +# Class: (transferrin receptor protein 1) + +AnnotationAssertion(Annotation( "PRO:WCB") "A protein that is a translation product of the human TFRC gene or a 1:1 ortholog thereof.") +AnnotationAssertion(Annotation( "PRO:DNx") "p90") +AnnotationAssertion( "CD71") +AnnotationAssertion( "T9") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "TFRC") +AnnotationAssertion( "TfR") +AnnotationAssertion( "TfR1") +AnnotationAssertion( "protein") +AnnotationAssertion( "TR") +AnnotationAssertion(Annotation( ) "Trfr") +AnnotationAssertion( "PR:000001945") +AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") +AnnotationAssertion(rdfs:label "transferrin receptor protein 1") +AnnotationAssertion( ) +SubClassOf( ) + +# Class: (tumor necrosis factor receptor superfamily member 11A) + +AnnotationAssertion(Annotation( "PRO:WCB") "A protein that is a translation product of the human TNFRSF11A gene or a 1:1 ortholog thereof.") +AnnotationAssertion( "IUPHARobj:1881") +AnnotationAssertion( "PIRSF:PIRSF038806") +AnnotationAssertion( "CD265") +AnnotationAssertion( "ODFR") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "TNFRSF11A") +AnnotationAssertion( "osteoclast differentiation factor receptor") +AnnotationAssertion( "receptor activator of NF-KB") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( ) "RANK") +AnnotationAssertion( "PR:000001954") +AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") +AnnotationAssertion(rdfs:label "tumor necrosis factor receptor superfamily member 11A") +AnnotationAssertion( ) +SubClassOf( ) + +# Class: (CD27 molecule) + +AnnotationAssertion(Annotation( "PRO:WCB") "A protein that is a translation product of the human CD27 gene or a 1:1 ortholog thereof.") +AnnotationAssertion( "IUPHARobj:1876") +AnnotationAssertion( "PIRSF:PIRSF001966") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "CD27") +AnnotationAssertion( "CD27L receptor") +AnnotationAssertion( "T-cell activation antigen CD27") +AnnotationAssertion( "tumor necrosis factor receptor superfamily member 7") +AnnotationAssertion( "protein") +AnnotationAssertion( "T14") +AnnotationAssertion(Annotation( ) "TNFRSF7") +AnnotationAssertion( "PR:000001963") +AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") +AnnotationAssertion(rdfs:label "CD27 molecule") +SubClassOf( ) + +# Class: (urokinase plasminogen activator surface receptor) + +AnnotationAssertion(Annotation( "PRO:WCB") "A protein that is a translation product of the human PLAUR gene or a 1:1 ortholog thereof.") +AnnotationAssertion( "PIRSF:PIRSF002022") +AnnotationAssertion( "CD87") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "PLAUR") +AnnotationAssertion( "U-PAR") +AnnotationAssertion( "monocyte activation antigen Mo3") +AnnotationAssertion( "uPAR") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( ) "MO3") +AnnotationAssertion(Annotation( ) "UPAR") +AnnotationAssertion( "PR:000001969") +AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") +AnnotationAssertion(rdfs:label "urokinase plasminogen activator surface receptor") +AnnotationAssertion( ) +SubClassOf( ) + +# Class: (vascular endothelial growth factor receptor) + +AnnotationAssertion(Annotation( "PRO:WCB") "A protein with core architecture consisting of a signal sequence, followed by 7 Ig-like domains (Pfam:PF00047, Pfam:PF07679, or Pfam:PF07686), a transmembrane region, and a cytoplasmic Protein tyrosine kinase domain.") +AnnotationAssertion( "PIRSF:PIRSF038502") +AnnotationAssertion( "protein") +AnnotationAssertion( "PR:000001971") +AnnotationAssertion(rdfs:comment "Category=family.") +AnnotationAssertion(rdfs:label "vascular endothelial growth factor receptor") +SubClassOf( ) + +# Class: (receptor-type tyrosine-protein kinase FLT3) + +AnnotationAssertion(Annotation( "PRO:WCB") "A CSF-1/PDGF receptor-type tyrosine-protein kinase that is a translation product of the human FLT3 gene or a 1:1 ortholog thereof.") +AnnotationAssertion( "IUPHARobj:1807") +AnnotationAssertion( "PIRSF:PIRSF500949") +AnnotationAssertion( "FL cytokine receptor") +AnnotationAssertion( "FLK-2") +AnnotationAssertion( "FLT-3") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "FLT3") +AnnotationAssertion( "Fms-like tyrosine kinase 3") +AnnotationAssertion( "fetal liver kinase 2") +AnnotationAssertion( "stem cell tyrosine kinase 1") +AnnotationAssertion( "tyrosine-protein kinase FLT3") +AnnotationAssertion( "tyrosine-protein kinase receptor FLT3") +AnnotationAssertion( "tyrosine-protein kinase receptor flk-2") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( ) "CD135") +AnnotationAssertion(Annotation( ) "FLK2") +AnnotationAssertion( "STK-1") +AnnotationAssertion(Annotation( ) "STK1") +AnnotationAssertion( "PR:000002001") +AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") +AnnotationAssertion(rdfs:label "receptor-type tyrosine-protein kinase FLT3") +AnnotationAssertion( ) +SubClassOf( ) + +# Class: (complement component C1q receptor) + +AnnotationAssertion(Annotation( "PRO:WCB") "A thrombomodulin-like receptor that is a translation product of the human CD93 gene or a 1:1 ortholog thereof.") +AnnotationAssertion( "C1q/MBL/SPA receptor") +AnnotationAssertion( "C1qR") +AnnotationAssertion( "C1qR(p)") +AnnotationAssertion( "C1qRp") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "CD93") +AnnotationAssertion( "CDw93") +AnnotationAssertion( "Ly-68") +AnnotationAssertion( "cell surface antigen AA4") +AnnotationAssertion( "complement component 1 q subcomponent receptor 1") +AnnotationAssertion( "lymphocyte antigen 68") +AnnotationAssertion( "matrix-remodeling-associated protein 4") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( ) "Aa4") +AnnotationAssertion(Annotation( ) "C1QR1") +AnnotationAssertion(Annotation( ) "Ly68") +AnnotationAssertion(Annotation( ) "MXRA4") +AnnotationAssertion( "PR:000002037") +AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") +AnnotationAssertion(rdfs:label "complement component C1q receptor") +AnnotationAssertion( ) +SubClassOf( ) + +# Class: (glutamyl aminopeptidase) + +AnnotationAssertion(Annotation( "PRO:WCB") "A membrane alanyl aminopeptidase-like metallopeptidase that is a translation product of the human ENPEP gene or a 1:1 ortholog thereof.") +AnnotationAssertion( "IUPHARobj:1568") +AnnotationAssertion( "AP-A") +AnnotationAssertion( "BP-1/6C3 antigen") +AnnotationAssertion( "CD249") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "ENPEP") +AnnotationAssertion( "aminopeptidase A") +AnnotationAssertion( "differentiation antigen gp160") +AnnotationAssertion( "protein") +AnnotationAssertion( "EAP") +AnnotationAssertion( "PR:000002039") +AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") +AnnotationAssertion(rdfs:label "glutamyl aminopeptidase") +AnnotationAssertion( ) +SubClassOf( ) + +# Class: (macrophage colony-stimulating factor 1 receptor) + +AnnotationAssertion(Annotation( "PRO:WCB") "A CSF-1/PDGF receptor-type tyrosine-protein kinase that is a translation product of the human CSF1R gene or a 1:1 ortholog thereof.") +AnnotationAssertion( "IUPHARobj:1806") +AnnotationAssertion( "PIRSF:PIRSF500947") +AnnotationAssertion( "CD115") +AnnotationAssertion( "CSF-1 receptor") +AnnotationAssertion( "CSF-1-R") +AnnotationAssertion( "CSF-1R") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "CSF1R") +AnnotationAssertion( "M-CSF-R") +AnnotationAssertion( "proto-oncogene c-Fms") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( ) "Csfmr") +AnnotationAssertion(Annotation( ) "FMS") +AnnotationAssertion( "PR:000002062") +AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") +AnnotationAssertion(rdfs:label "macrophage colony-stimulating factor 1 receptor") +AnnotationAssertion( ) +SubClassOf( ) + +# Class: (mast/stem cell growth factor receptor) + +AnnotationAssertion(Annotation( "PRO:WCB") "A CSF-1/PDGF receptor-type tyrosine-protein kinase that is a translation product of the human KIT gene or a 1:1 ortholog thereof.") +AnnotationAssertion( "IUPHARobj:1805") +AnnotationAssertion( "PIRSF:PIRSF500951") +AnnotationAssertion( "CD117") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "KIT") +AnnotationAssertion( "proto-oncogene c-Kit") +AnnotationAssertion( "tyrosine-protein kinase Kit") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( ) "SCFR") +AnnotationAssertion(Annotation( ) "Sl") +AnnotationAssertion( "PR:000002065") +AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") +AnnotationAssertion(rdfs:label "mast/stem cell growth factor receptor") +SubClassOf( ) + +# Class: (vascular endothelial growth factor receptor 2) + +AnnotationAssertion(Annotation( "PRO:WCB") "A vascular endothelial growth factor receptor that is a translation product of the human KDR gene or a 1:1 ortholog thereof.") +AnnotationAssertion( "IUPHARobj:1813") +AnnotationAssertion( "CD309") +AnnotationAssertion( "FLK-1") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "KDR") +AnnotationAssertion( "VEGFR-2") +AnnotationAssertion( "fetal liver kinase 1") +AnnotationAssertion( "kinase NYK") +AnnotationAssertion( "kinase insert domain receptor") +AnnotationAssertion( "protein-tyrosine kinase receptor flk-1") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( ) "FLK1") +AnnotationAssertion(Annotation( ) "VEGFR2") +AnnotationAssertion( "PR:000002112") +AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") +AnnotationAssertion(rdfs:label "vascular endothelial growth factor receptor 2") +AnnotationAssertion( ) +SubClassOf( ) + +# Class: (Ly-6-like protein) + +AnnotationAssertion(Annotation( "PRO:CNA") "A protein that is the translation product of any of the LY6 genes (LY6A-LY6I).") +AnnotationAssertion( "PIRSF:PIRSF002021") +AnnotationAssertion( "protein") +AnnotationAssertion( "PR:000002976") +AnnotationAssertion(rdfs:comment "Category=family.") +AnnotationAssertion(rdfs:label "Ly-6-like protein") +SubClassOf( ) + +# Class: (killer cell lectin-like receptor subfamily B member 1C) + +AnnotationAssertion(Annotation( "PRO:CNA") "A KLRB1-like protein that is a translation product of the mouse Klrb1c gene or a 1:1 ortholog thereof.") +AnnotationAssertion( "CD161 antigen-like family member C") +AnnotationAssertion( "CD161c") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "Klrb1c") +AnnotationAssertion( "NK1.1") +AnnotationAssertion( "NKR-P1 40") +AnnotationAssertion( "NKR-P1.9") +AnnotationAssertion( "NKR-P1C") +AnnotationAssertion( "ly-55c") +AnnotationAssertion( "lymphocyte antigen 55c") +AnnotationAssertion( "natural killer cell surface protein P1-40") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( ) "Ly55c") +AnnotationAssertion(Annotation( ) "Nkrp1c") +AnnotationAssertion( "PR:000002977") +AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") +AnnotationAssertion(rdfs:label "killer cell lectin-like receptor subfamily B member 1C") +SubClassOf( ) + +# Class: (lymphocyte antigen 6G) + +AnnotationAssertion(Annotation( "PRO:CNA") "An Ly-6-like protein that is a translation product of the mouse Ly6g gene or a 1:1 ortholog thereof.") +AnnotationAssertion( "Ly-6G") +AnnotationAssertion( "Ly-6G.1") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "Ly6g") +AnnotationAssertion( "protein") +AnnotationAssertion( "PR:000002978") +AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") +AnnotationAssertion(rdfs:label "lymphocyte antigen 6G") +SubClassOf( ) + +# Class: (lymphocyte antigen 6A-2/6E-1) + +AnnotationAssertion(Annotation( "PRO:CNA") "An Ly-6-like protein that is a translation product of the mouse Ly6a gene or a 1:1 ortholog thereof.") +AnnotationAssertion( "Ly-6A.2/Ly-6E.1") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "Ly6a") +AnnotationAssertion( "T-cell-activating protein") +AnnotationAssertion( "stem cell antigen 1") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( ) "Ly6") +AnnotationAssertion( "SCA-1") +AnnotationAssertion( "TAP") +AnnotationAssertion( "PR:000002979") +AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") +AnnotationAssertion(rdfs:label "lymphocyte antigen 6A-2/6E-1") +SubClassOf( ) + +# Class: (lymphocyte antigen 6C2) + +AnnotationAssertion(Annotation( "PRO:CNA") "An Ly-6-like protein that is a translation product of the mouse Ly6c2 gene or a 1:1 ortholog thereof.") +AnnotationAssertion( "Ly-6C2") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "Ly6c2") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( ) "Ly6c") +AnnotationAssertion( "PR:000002980") +AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") +AnnotationAssertion(rdfs:label "lymphocyte antigen 6C2") +SubClassOf( ) + +# Class: (lymphocyte antigen 76 (mouse)) + +AnnotationAssertion(Annotation( "PMID:10848813") Annotation( "PRO:DAN") "A protein that is a translation product of the Ly76 gene in mouse.") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mLy76") +AnnotationAssertion( "ter-119") +AnnotationAssertion( "ter119") +AnnotationAssertion( "protein") +AnnotationAssertion( "PR:000002981") +AnnotationAssertion(rdfs:comment "Category=organism-gene. Requested by=CL.") +AnnotationAssertion(rdfs:label "lymphocyte antigen 76 (mouse)") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (V(D)J recombination-activating protein 1) + +AnnotationAssertion(Annotation( "PRO:CNA") "A protein that is a translation product of the human RAG1 gene or a 1:1 ortholog thereof.") +AnnotationAssertion( "RAG-1") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "RAG1") +AnnotationAssertion( "RING finger protein 74") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( ) "RNF74") +AnnotationAssertion( "PR:000003457") +AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") +AnnotationAssertion(rdfs:label "V(D)J recombination-activating protein 1") +AnnotationAssertion( ) +SubClassOf( ) + +# Class: (V(D)J recombination-activating protein 2) + +AnnotationAssertion(Annotation( "PRO:CNA") "A protein that is a translation product of the human RAG2 gene or a 1:1 ortholog thereof.") +AnnotationAssertion( "RAG-2") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "RAG2") +AnnotationAssertion( "protein") +AnnotationAssertion( "PR:000003460") +AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") +AnnotationAssertion(rdfs:label "V(D)J recombination-activating protein 2") +AnnotationAssertion( ) +SubClassOf( ) + +# Class: (lactosylceramide 4-alpha-galactosyltransferase) + +AnnotationAssertion(Annotation( "PRO:DNx") "A protein that is a translation product of the human A4GALT gene or a 1:1 ortholog thereof.") +AnnotationAssertion(Annotation( "PRO:DNx") "alpha-1,4-N-acetylglucosaminyltransferase") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "A4GALT") +AnnotationAssertion( "CD77 synthase") +AnnotationAssertion( "Gb3 synthase") +AnnotationAssertion( "P1/Pk synthase") +AnnotationAssertion( "UDP-galactose:beta-D-galactosyl-beta1-R 4-alpha-D-galactosyltransferase") +AnnotationAssertion( "alpha-1,4-galactosyltransferase") +AnnotationAssertion( "alpha4Gal-T1") +AnnotationAssertion( "globotriaosylceramide synthase") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( ) "A14GALT") +AnnotationAssertion(Annotation( ) "A4GALT1") +AnnotationAssertion( "PR:000003516") +AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") +AnnotationAssertion(rdfs:label "lactosylceramide 4-alpha-galactosyltransferase") +AnnotationAssertion( ) +SubClassOf( ) + +# Class: (CCAAT/enhancer-binding protein alpha) + +AnnotationAssertion(Annotation( "PRO:DNx") "A protein that is a translation product of the human CEBPA gene or a 1:1 ortholog thereof.") +AnnotationAssertion( "C/EBP alpha") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "CEBPA") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( ) "CEBP") +AnnotationAssertion( "PR:000005307") +AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") +AnnotationAssertion(rdfs:label "CCAAT/enhancer-binding protein alpha") +AnnotationAssertion( ) +SubClassOf( ) + +# Class: (DNA nucleotidylexotransferase) + +AnnotationAssertion(Annotation( "PRO:DNx") "A protein that is a translation product of the human DNTT gene or a 1:1 ortholog thereof.") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "DNTT") +AnnotationAssertion( "terminal addition enzyme") +AnnotationAssertion( "terminal deoxynucleotidyltransferase") +AnnotationAssertion( "terminal transferase") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( ) "TDT") +AnnotationAssertion( "PR:000006611") +AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") +AnnotationAssertion(rdfs:label "DNA nucleotidylexotransferase") +AnnotationAssertion( ) +SubClassOf( ) + # Class: (fibroblast growth factor 8) AnnotationAssertion(Annotation( "PRO:DNx") "A protein that is a translation product of the human FGF8 gene or a 1:1 ortholog thereof.") @@ -62189,6 +146614,22 @@ AnnotationAssertion(rdfs:label "fi AnnotationAssertion( ) SubClassOf( ) +# Class: (protein c-Fos) + +AnnotationAssertion(Annotation( "PRO:DNx") "A protein that is a translation product of the human FOS gene or a 1:1 ortholog thereof.") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "FOS") +AnnotationAssertion( "G0/G1 switch regulatory protein 7") +AnnotationAssertion( "cellular oncogene fos") +AnnotationAssertion( "proto-oncogene protein c-fos") +AnnotationAssertion( "transcription factor AP-1 subunit c-Fos") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( ) "G0S7") +AnnotationAssertion( "PR:000007597") +AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") +AnnotationAssertion(rdfs:label "protein c-Fos") +AnnotationAssertion( ) +SubClassOf( ) + # Class: (forkhead box protein N1) AnnotationAssertion(Annotation( "PRO:DNx") "A protein that is a translation product of the human FOXN1 gene or a 1:1 ortholog thereof.") @@ -62209,6 +146650,77 @@ AnnotationAssertion(rdfs:label "fo AnnotationAssertion( ) SubClassOf( ) +# Class: (erythroid transcription factor) + +AnnotationAssertion(Annotation( "PRO:DNx") "A protein that is a translation product of the human GATA1 gene or a 1:1 ortholog thereof.") +AnnotationAssertion( "Eryf1") +AnnotationAssertion( "GATA-1") +AnnotationAssertion( "GATA-binding factor 1") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "GATA1") +AnnotationAssertion( "NF-E1 DNA-binding protein") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( ) "ERYF1") +AnnotationAssertion( "GF-1") +AnnotationAssertion(Annotation( ) "GF1") +AnnotationAssertion( "PR:000007857") +AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") +AnnotationAssertion(rdfs:label "erythroid transcription factor") +AnnotationAssertion( ) +SubClassOf( ) + +# Class: (endothelial transcription factor GATA-2) + +AnnotationAssertion(Annotation( "PRO:DNx") "A protein that is a translation product of the human GATA2 gene or a 1:1 ortholog thereof.") +AnnotationAssertion( "GATA-binding protein 2") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "GATA2") +AnnotationAssertion( "protein") +AnnotationAssertion( "PR:000007858") +AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") +AnnotationAssertion(rdfs:label "endothelial transcription factor GATA-2") +AnnotationAssertion( ) +SubClassOf( ) + +# Class: (glial fibrillary acidic protein) + +AnnotationAssertion(Annotation( "PRO:DNx") "A protein that is a translation product of the human GFAP gene or a 1:1 ortholog thereof.") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "GFAP") +AnnotationAssertion( "protein") +AnnotationAssertion( "PR:000007939") +AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") +AnnotationAssertion(rdfs:label "glial fibrillary acidic protein") +AnnotationAssertion( ) +SubClassOf( ) + +# Class: (insulin gene translation product) + +AnnotationAssertion(Annotation( "PRO:DNx") "An insulin family protein that is a translation product of the human INS gene or a 1:1 ortholog thereof.") +AnnotationAssertion(Annotation( "PRO:DAN") "insulin") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "INS") +AnnotationAssertion( "protein") +AnnotationAssertion( "PR:000009054") +AnnotationAssertion(rdfs:comment "Category=gene.") +AnnotationAssertion(rdfs:label "insulin gene translation product") +AnnotationAssertion( ) +SubClassOf( ) + +# Class: (integrin alpha-IIb) + +AnnotationAssertion(Annotation( "PRO:DNx") "An integrin alpha lacking A domain that is a translation product of the human ITGA2B gene or a 1:1 ortholog thereof.") +AnnotationAssertion( "IUPHARobj:2441") +AnnotationAssertion( "CD41") +AnnotationAssertion( "GPIIb") +AnnotationAssertion( "GPalpha IIb") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "ITGA2B") +AnnotationAssertion( "platelet membrane glycoprotein IIb") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( ) "GP2B") +AnnotationAssertion(Annotation( ) "ITGAB") +AnnotationAssertion( "PR:000009127") +AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") +AnnotationAssertion(rdfs:label "integrin alpha-IIb") +AnnotationAssertion( ) +SubClassOf( ) + # Class: (lactotransferrin) AnnotationAssertion(Annotation( "PRO:DNx") "A protein that is a translation product of the human LTF gene or a 1:1 ortholog thereof.") @@ -62238,6 +146750,48 @@ AnnotationAssertion(rdfs:label "my AnnotationAssertion( ) SubClassOf( ) +# Class: (nuclear factor NF-kappa-B p100 subunit) + +AnnotationAssertion(Annotation( "PRO:DNx") "A transcription factor NF-kappa-B subunit that is a translation product of the human NFKB2 gene or a 1:1 ortholog thereof.") +AnnotationAssertion( "DNA-binding factor KBF2") +AnnotationAssertion( "H2TF1") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "NFKB2") +AnnotationAssertion( "lymphocyte translocation chromosome 10 protein") +AnnotationAssertion( "lyt10") +AnnotationAssertion( "nuclear factor of kappa light polypeptide gene enhancer in B-cells 2") +AnnotationAssertion( "oncogene Lyt-10") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( ) "LYT10") +AnnotationAssertion( "PR:000011178") +AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") +AnnotationAssertion(rdfs:label "nuclear factor NF-kappa-B p100 subunit") +AnnotationAssertion( ) +SubClassOf( ) + +# Class: (prolactin) + +AnnotationAssertion(Annotation( "PRO:DNx") "A somatotropin hormone family member that is a translation product of the human PRL gene or a 1:1 ortholog thereof.") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "PRL") +AnnotationAssertion( "protein") +AnnotationAssertion( "PR:000013246") +AnnotationAssertion(rdfs:comment "Category=gene.") +AnnotationAssertion(rdfs:label "prolactin") +AnnotationAssertion( ) +SubClassOf( ) + +# Class: (renin) + +AnnotationAssertion(Annotation( "PRO:DAN") "An angiotensinogenase that is a translation product of the human REN gene or a 1:1 ortholog thereof.") +AnnotationAssertion( "IUPHARobj:2413") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "REN") +AnnotationAssertion( "protein") +AnnotationAssertion( "angiotensinogenase") +AnnotationAssertion( "PR:000013883") +AnnotationAssertion(rdfs:comment "Category=gene.") +AnnotationAssertion(rdfs:label "renin") +AnnotationAssertion( ) +SubClassOf( ) + # Class: (sonic hedgehog protein) AnnotationAssertion(Annotation( "PRO:DNx") "A protein that is a translation product of the human SHH gene or a 1:1 ortholog thereof.") @@ -62281,6 +146835,25 @@ AnnotationAssertion(rdfs:label "SC AnnotationAssertion( ) SubClassOf( ) +# Class: (T-cell acute lymphocytic leukemia protein 1) + +AnnotationAssertion(Annotation( "PRO:DNx") "A protein that is a translation product of the human TAL1 gene or a 1:1 ortholog thereof.") +AnnotationAssertion( "T-cell leukemia/lymphoma protein 5") +AnnotationAssertion( "TAL-1") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "TAL1") +AnnotationAssertion( "bHLHa17") +AnnotationAssertion( "class A basic helix-loop-helix protein 17") +AnnotationAssertion( "stem cell protein") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( ) "BHLHA17") +AnnotationAssertion(Annotation( ) "SCL") +AnnotationAssertion(Annotation( ) "TCL5") +AnnotationAssertion( "PR:000016043") +AnnotationAssertion(rdfs:comment "Category=gene. Requested by=CL.") +AnnotationAssertion(rdfs:label "T-cell acute lymphocytic leukemia protein 1") +AnnotationAssertion( ) +SubClassOf( ) + # Class: (thyroglobulin) AnnotationAssertion(Annotation( "PRO:DNx") "A protein that is a translation product of the human TG gene or a 1:1 ortholog thereof.") @@ -62315,9 +146888,186 @@ AnnotationAssertion(Annotation( "protein") AnnotationAssertion( "PR:000018264") AnnotationAssertion(rdfs:label "proteolytic cleavage product") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (CD48 molecule proteolytic cleavage product) + +AnnotationAssertion(Annotation( "PRO:DNx") "A CD48 molecule that has been processed by proteolytic cleavage.") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "CD48/ClvPrd") +AnnotationAssertion( "protein") +AnnotationAssertion( "PR:000018381") +AnnotationAssertion(rdfs:comment "Category=modification.") +AnnotationAssertion(rdfs:label "CD48 molecule proteolytic cleavage product") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (carcinoembryonic antigen-related cell adhesion molecule 8 proteolytic cleavage product) + +AnnotationAssertion(Annotation( "PRO:DNx") "A carcinoembryonic antigen-related cell adhesion molecule 8 that has been processed by proteolytic cleavage.") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "CEACAM8/ClvPrd") +AnnotationAssertion( "protein") +AnnotationAssertion( "PR:000018406") +AnnotationAssertion(rdfs:comment "Category=modification.") +AnnotationAssertion(rdfs:label "carcinoembryonic antigen-related cell adhesion molecule 8 proteolytic cleavage product") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (Thy-1 membrane glycoprotein proteolytic cleavage product) + +AnnotationAssertion(Annotation( "PRO:DNx") "A Thy-1 membrane glycoprotein that has been processed by proteolytic cleavage.") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "THY1/ClvPrd") +AnnotationAssertion( "protein") +AnnotationAssertion( "PR:000018546") +AnnotationAssertion(rdfs:comment "Category=modification.") +AnnotationAssertion(rdfs:label "Thy-1 membrane glycoprotein proteolytic cleavage product") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cathepsin K proteolytic cleavage product) + +AnnotationAssertion(Annotation( "PRO:DNx") "A cathepsin K that has been processed by proteolytic cleavage.") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "CTSK/ClvPrd") +AnnotationAssertion( "protein") +AnnotationAssertion( "PR:000018547") +AnnotationAssertion(rdfs:comment "Category=modification.") +AnnotationAssertion(rdfs:label "cathepsin K proteolytic cleavage product") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (low affinity immunoglobulin epsilon Fc receptor proteolytic cleavage product) + +AnnotationAssertion(Annotation( "PRO:DNx") "A low affinity immunoglobulin epsilon Fc receptor that has been processed by proteolytic cleavage.") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "FCER2/ClvPrd") +AnnotationAssertion( "protein") +AnnotationAssertion( "PR:000018568") +AnnotationAssertion(rdfs:comment "Category=modification.") +AnnotationAssertion(rdfs:label "low affinity immunoglobulin epsilon Fc receptor proteolytic cleavage product") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (scavenger receptor cysteine-rich type 1 protein M130 proteolytic cleavage product) + +AnnotationAssertion(Annotation( "PRO:DNx") "A scavenger receptor cysteine-rich type 1 protein M130 that has been processed by proteolytic cleavage.") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "CD163/ClvPrd") +AnnotationAssertion( "protein") +AnnotationAssertion( "PR:000018594") +AnnotationAssertion(rdfs:comment "Category=modification.") +AnnotationAssertion(rdfs:label "scavenger receptor cysteine-rich type 1 protein M130 proteolytic cleavage product") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (transferrin receptor protein 1 proteolytic cleavage product) + +AnnotationAssertion(Annotation( "PRO:DNx") "A transferrin receptor protein 1 that has been processed by proteolytic cleavage.") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "TFRC/ClvPrd") +AnnotationAssertion( "protein") +AnnotationAssertion( "PR:000018603") +AnnotationAssertion(rdfs:comment "Category=modification.") +AnnotationAssertion(rdfs:label "transferrin receptor protein 1 proteolytic cleavage product") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (integrin alpha-IIb proteolytic cleavage product) + +AnnotationAssertion(Annotation( "PRO:DNx") "An integrin alpha-IIb that has been processed by proteolytic cleavage.") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "ITGA2B/ClvPrd") +AnnotationAssertion( "protein") +AnnotationAssertion( "PR:000020329") +AnnotationAssertion(rdfs:comment "Category=modification.") +AnnotationAssertion(rdfs:label "integrin alpha-IIb proteolytic cleavage product") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (lactotransferrin proteolytic cleavage product) + +AnnotationAssertion(Annotation( "PRO:DNx") "A lactotransferrin that has been processed by proteolytic cleavage.") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "LTF/ClvPrd") +AnnotationAssertion( "protein") +AnnotationAssertion( "PR:000020497") +AnnotationAssertion(rdfs:comment "Category=modification.") +AnnotationAssertion(rdfs:label "lactotransferrin proteolytic cleavage product") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (nuclear factor NF-kappa-B p100 subunit proteolytic cleavage product) + +AnnotationAssertion(Annotation( "PRO:DNx") "A nuclear factor NF-kappa-B p100 subunit that has been processed by proteolytic cleavage.") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "NFKB2/ClvPrd") +AnnotationAssertion( "protein") +AnnotationAssertion( "PR:000020735") +AnnotationAssertion(rdfs:comment "Category=modification.") +AnnotationAssertion(rdfs:label "nuclear factor NF-kappa-B p100 subunit proteolytic cleavage product") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (sonic hedgehog protein proteolytic cleavage product) + +AnnotationAssertion(Annotation( "PRO:DNx") "A sonic hedgehog protein that has been processed by proteolytic cleavage.") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "SHH/ClvPrd") +AnnotationAssertion( "protein") +AnnotationAssertion( "PR:000021468") +AnnotationAssertion(rdfs:comment "Category=modification.") +AnnotationAssertion(rdfs:label "sonic hedgehog protein proteolytic cleavage product") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (CD2 molecule proteolytic cleavage product) + +AnnotationAssertion(Annotation( "PRO:DNx") "A CD2 molecule that has been processed by proteolytic cleavage.") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "CD2/ClvPrd") +AnnotationAssertion( "protein") +AnnotationAssertion( "PR:000025455") +AnnotationAssertion(rdfs:comment "Category=modification.") +AnnotationAssertion(rdfs:label "CD2 molecule proteolytic cleavage product") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (integrin alpha) + +AnnotationAssertion(Annotation( "PMID:19693543") "A protein that is composed of a long N-terminal extracellular domain, a transmembrane domain and a short cytoplasmic C-terminal domain. The N-terminal domain contains beta-propeller repeats (interrupted by an A domain in a subset of integrins alpha), while the C-terminal domain contains a GFFxR motif.") +AnnotationAssertion( "protein") +AnnotationAssertion( "PR:000025796") +AnnotationAssertion(rdfs:comment "Category=family. Integrins are heterodimeric complexes of an alpha and a beta subunit. They are a structurally elaborate family of adhesion molecules that transmit signals bidirectionally across the plasma membrane by undergoing large-scale structural rearrangements. By regulating cell-cell and cell-matrix contacts, integrins participate in a wide-range of biological interactions including development, tissue repair, angiogenesis, inflammation and hemostasis. [PMID:10402956, PMID:11988479, PMID:9676575].") +AnnotationAssertion(rdfs:label "integrin alpha") +SubClassOf( ) + +# Class: (integrin alpha lacking A domain) + +AnnotationAssertion(Annotation( "PRO:DAN") "An integrin alpha that lacks an A domain. This type of integrin is often cleaved into heavy and light chains.") +AnnotationAssertion( "PIRSF:PIRSF005666") +AnnotationAssertion(Annotation( "PRO:DAN") Annotation( ) "fam:ITGAsansA") +AnnotationAssertion( "protein") +AnnotationAssertion( "PR:000025797") +AnnotationAssertion(rdfs:comment "Category=family.") +AnnotationAssertion(rdfs:label "integrin alpha lacking A domain") +SubClassOf( ) + # Class: (CALCA gene translation product) AnnotationAssertion(Annotation( "MGI:2151253") Annotation( "PRO:CNA") "A protein that is a translation product of the human CALCA gene or a 1:1 ortholog thereof.") @@ -62330,6 +147080,19 @@ AnnotationAssertion(rdfs:label "CA AnnotationAssertion( ) SubClassOf( ) +# Class: (CALCA gene translation product (mouse)) + +AnnotationAssertion(Annotation( "MGI:2151253") Annotation( "PRO:HJD") "A CALCA gene translation product that is encoded in the genome of mouse.") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mCALCA") +AnnotationAssertion( "protein") +AnnotationAssertion( "PR:000027223") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "CALCA gene translation product (mouse)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (casein derived peptide) AnnotationAssertion(Annotation( "PRO:DAN") "A proteolytic cleavage product that is derived from any of the casein milk proteins.") @@ -62340,6 +147103,149 @@ AnnotationAssertion(rdfs:comment " AnnotationAssertion(rdfs:label "casein derived peptide") SubClassOf( ) +# Class: (Mus musculus protein) + +AnnotationAssertion(Annotation( "PRO:DAN") "A protein that is encoded in the genome of Mus musculus.") +AnnotationAssertion(Annotation( "PRO:DAN") Annotation( ) "mouse protein") +AnnotationAssertion( "protein") +AnnotationAssertion( "PR:000029032") +AnnotationAssertion(rdfs:label "Mus musculus protein") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (Gallus gallus protein) + +AnnotationAssertion(Annotation( "PRO:DAN") "A protein that is encoded in the genome of Gallus gallus.") +AnnotationAssertion(Annotation( "PRO:DAN") Annotation( ) "chicken protein") +AnnotationAssertion( "protein") +AnnotationAssertion( "PR:000029063") +AnnotationAssertion(rdfs:label "Gallus gallus protein") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (Homo sapiens protein) + +AnnotationAssertion(Annotation( "PRO:DAN") "A protein that is encoded in the genome of Homo sapiens.") +AnnotationAssertion(Annotation( "PRO:DAN") Annotation( ) "human protein") +AnnotationAssertion( "protein") +AnnotationAssertion( "PR:000029067") +AnnotationAssertion(rdfs:label "Homo sapiens protein") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (somatotropin hormone family member) + +AnnotationAssertion(Annotation( "PRO:DAN") "A protein that is a standalone version of the Hormone_1 domain (Pfam:PF00103). In the immature form, the domain is preceded by a signal peptide.") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "fam:GH1") +AnnotationAssertion( "protein") +AnnotationAssertion( "PR:000029968") +AnnotationAssertion(rdfs:comment "Category=family.") +AnnotationAssertion(rdfs:label "somatotropin hormone family member") +SubClassOf( ) + +# Class: (CALCA gene translation product (human)) + +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( "UniProtKB:P06881") "A CALCA gene translation product that is encoded in the genome of human.") +AnnotationAssertion(Annotation( "UniProtKB:P06881") "CALC1 (human)") +AnnotationAssertion(Annotation( "UniProtKB:P06881") "CGRP-I (human)") +AnnotationAssertion(Annotation( "UniProtKB:P06881") "alpha-type CGRP (human)") +AnnotationAssertion(Annotation( "UniProtKB:P06881") "calcitonin gene-related peptide I (human)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hCALCA") +AnnotationAssertion( "protein") +AnnotationAssertion( "PR:000030026") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "CALCA gene translation product (human)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (G-protein coupled receptor) + +AnnotationAssertion(Annotation( "IUPHARfam:694") Annotation( "PRO:DAN") Annotation( "Wikipedia:GPCR") "A protein that has G protein-coupled receptor (GPCR) activity. Each GPCR consists of a single polypeptide with an extracellular N-terminus, an intracellular C-terminus and seven hydrophobic transmembrane domains (TM1-TM7) linked by three extracellular loops (ECL1-ECL3) and three intracellular loops (ICL1-ICL3). GPCRs function as part of a heterotrimeric complex to transmit an extracellular signal across the membrane by activating an associated G-protein via the exchange of GDP for GTP on the alpha subunit.") +AnnotationAssertion(Annotation( "IUPHARfam:694") "7TM receptor") +AnnotationAssertion(Annotation( "IUPHARfam:694") "seven-transmembrane receptor") +AnnotationAssertion( "IUPHARfam:694") +AnnotationAssertion(Annotation( "PRO:DAN") Annotation( ) "fam:GPCR") +AnnotationAssertion( "protein") +AnnotationAssertion( "PR:000030035") +AnnotationAssertion(rdfs:comment "Category=family. Classification based on GRAFS system. [PMID:12761335]") +AnnotationAssertion(rdfs:label "G-protein coupled receptor") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (eukaryotic protein) + +AnnotationAssertion(Annotation( "PRO:DAN") "A protein that is encoded in the genome of some Eukaryota.") +AnnotationAssertion(Annotation( "PRO:DAN") "Eukaryota protein") +AnnotationAssertion( "protein") +AnnotationAssertion( "PR:000036194") +AnnotationAssertion(rdfs:label "eukaryotic protein") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (CALCA gene translation product (chicken)) + +AnnotationAssertion(Annotation( "PRO:DAN") "A CALCA gene translation product that is encoded in the genome of chicken.") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "chick-CALCA") +AnnotationAssertion( "protein") +AnnotationAssertion( "PR:000036870") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "CALCA gene translation product (chicken)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cathepsin-like protease) + +AnnotationAssertion(Annotation( "PRO:DAN") "A protein that is a translation product of some metazoan gene that encodes a signal peptide followed by a single Cathepsin propeptide inhibitor domain (Pfam:PF08246) followed by a single Papain family cysteine protease (Pfam:PF00112) domain at the C terminus.") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "fam:CTS") +AnnotationAssertion(Annotation( "PRO:DAN") "cathepsin") +AnnotationAssertion( "protein") +AnnotationAssertion( "PR:000040662") +AnnotationAssertion(rdfs:comment "Category=family.") +AnnotationAssertion(rdfs:label "cathepsin-like protease") +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (insulin family protein) + +AnnotationAssertion(Annotation( "PRO:DAN") "A protein that is a translation product of a gene that encodes a standalone Insulin (Pfam:PF00049) domain preceded by a signal peptide.") +AnnotationAssertion(Annotation( "PRO:DAN") Annotation( ) "fam:INS") +AnnotationAssertion( "protein") +AnnotationAssertion( "PR:000045358") +AnnotationAssertion(rdfs:comment "Category=family.") +AnnotationAssertion(rdfs:label "insulin family protein") +SubClassOf( ) + +# Class: (angiotensinogenase) + +AnnotationAssertion(Annotation( "PRO:DAN") "A protein that is a translation product of the mouse Ren1 or Ren2 genes, 1:1 orthologs thereof, or a semi-ortholog thereof.") +AnnotationAssertion(Annotation( "PRO:DAN") Annotation( ) "fam:angiotensinogenase") +AnnotationAssertion( "protein") +AnnotationAssertion( "PR:000050025") +AnnotationAssertion(rdfs:comment "Category=family.") +AnnotationAssertion(rdfs:label "angiotensinogenase") +SubClassOf( ) + +# Class: (receptor-type tyrosine-protein phosphatase C isoform CD45R) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "PRO:ADD") Annotation( "PRO:DAN") "A receptor-type tyrosine-protein phosphatase C that is a translation product of a transcript that minimally includes the region encoded by the variable exon 4(A).") +AnnotationAssertion( "CD45R") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "PTPRC/iso:CD45R") +AnnotationAssertion( "protein") +AnnotationAssertion( "PR:000050216") +AnnotationAssertion(rdfs:comment "Category=seqgroup. Requested by=CL.") +AnnotationAssertion(rdfs:label "receptor-type tyrosine-protein phosphatase C isoform CD45R") +SubClassOf( ) + # Class: (protein-containing material entity) AnnotationAssertion(Annotation( "PRO:DAN") "A material entity that minimally consists of a protein.") @@ -62351,9 +147257,3605 @@ AnnotationAssertion( "PR:000050567") AnnotationAssertion(rdfs:comment "Note: This includes single proteins and derivatives thereof (PR:000000001), protein-containing complexes (GO:0032991), and protein aggregates (PR:000050566).") AnnotationAssertion(rdfs:label "protein-containing material entity") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) SubClassOf( ) SubClassOf( ObjectSomeValuesFrom( )) +# Class: (interleukin-7 receptor alpha chain (chicken)) + +AnnotationAssertion(Annotation( "OMA:A1EA95") Annotation( "PRO:DNx") "An interleukin-7 receptor subunit alpha that is encoded in the genome of chicken.") +AnnotationAssertion( "UniProtKB:A1EA95") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "chick-IL7R") +AnnotationAssertion( "protein") +AnnotationAssertion( "PR:A1EA95") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "interleukin-7 receptor alpha chain (chicken)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (SCO-spondin (human)) + +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( "UniProtKB:A2VEC9") "A SCO-spondin that is encoded in the genome of human.") +AnnotationAssertion( "UniProtKB:A2VEC9") +AnnotationAssertion(Annotation( "UniProtKB:A2VEC9") "SCO-spondin pseudogene (human)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hSSPO") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:A2VEC9") Annotation( ) "KIAA2036") +AnnotationAssertion(Annotation( "UniProtKB:A2VEC9") Annotation( ) "SSPO") +AnnotationAssertion(Annotation( "UniProtKB:A2VEC9") Annotation( ) "SSPOP") +AnnotationAssertion( "PR:A2VEC9") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "SCO-spondin (human)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (CD14 molecule (chicken)) + +AnnotationAssertion(Annotation( "PRO:CNA") "A CD14 molecule that is encoded in the genome of chicken.") +AnnotationAssertion( "UniProtKB:B0BL87") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "chick-CD14") +AnnotationAssertion( "protein") +AnnotationAssertion( "PR:B0BL87") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "CD14 molecule (chicken)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (interleukin-5 receptor subunit alpha isoform 2 (chicken)) + +AnnotationAssertion(Annotation( "PRO:WCB") "An interleukin-5 receptor subunit alpha that is encoded in the genome of chicken.") +AnnotationAssertion( "UniProtKB:E1C261") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "chick-IL5RA") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:E1C261") Annotation( ) "IL-5R alpha") +AnnotationAssertion( "PR:E1C261") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "interleukin-5 receptor subunit alpha isoform 2 (chicken)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (uncharacterized protein, PROM1 translation product (chicken)) + +AnnotationAssertion(Annotation( "OMA:E1C9E2") Annotation( "PRO:CNA") "A prominin-1 that is encoded in the genome of chicken.") +AnnotationAssertion( "UniProtKB:E1C9E2") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "chick-PROM1") +AnnotationAssertion( "protein") +AnnotationAssertion( "PR:E1C9E2") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "uncharacterized protein, PROM1 translation product (chicken)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (uncharacterized protein, CD8A translation product (chicken)) + +AnnotationAssertion(Annotation( "PRO:CNA") "A T-cell surface glycoprotein CD8 alpha chain that is encoded in the genome of chicken.") +AnnotationAssertion( "UniProtKB:F1NXT4") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "chick-CD8A") +AnnotationAssertion( "protein") +AnnotationAssertion( "PR:F1NXT4") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "uncharacterized protein, CD8A translation product (chicken)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (thyroglobulin (mouse)) + +AnnotationAssertion(Annotation( "OMA:O08710") Annotation( "PRO:DNx") "A thyroglobulin that is encoded in the genome of mouse.") +AnnotationAssertion( "UniProtKB:O08710") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mTG") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:O08710") Annotation( ) "Tg") +AnnotationAssertion(Annotation( "UniProtKB:O08710") Annotation( ) "Tgn") +AnnotationAssertion( "PR:O08710") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "thyroglobulin (mouse)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (endothelial transcription factor GATA-2 (mouse)) + +AnnotationAssertion(Annotation( "OMA:O09100") Annotation( "PRO:DNx") "An endothelial transcription factor GATA-2 that is encoded in the genome of mouse.") +AnnotationAssertion( "UniProtKB:O09100") +AnnotationAssertion(Annotation( "UniProtKB:O09100") "GATA-binding protein 2 (mouse)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mGATA2") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:O09100") Annotation( ) "Gata2") +AnnotationAssertion( "PR:O09100") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "endothelial transcription factor GATA-2 (mouse)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (forkhead box protein N1 (human)) + +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( "UniProtKB:O15353") "A forkhead box protein N1 that is encoded in the genome of human.") +AnnotationAssertion( "UniProtKB:O15353") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hFOXN1") +AnnotationAssertion(Annotation( "UniProtKB:O15353") "winged-helix transcription factor nude (human)") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:O15353") Annotation( ) "FOXN1") +AnnotationAssertion(Annotation( "UniProtKB:O15353") Annotation( ) "RONU") +AnnotationAssertion(Annotation( "UniProtKB:O15353") Annotation( ) "WHN") +AnnotationAssertion( "PR:O15353") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "forkhead box protein N1 (human)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (tumor necrosis factor receptor superfamily member 11A (mouse)) + +AnnotationAssertion(Annotation( "OMA:O35305") Annotation( "PRO:DNx") "A tumor necrosis factor receptor superfamily member 11A that is encoded in the genome of mouse.") +AnnotationAssertion( "UniProtKB:O35305") +AnnotationAssertion(Annotation( "UniProtKB:O35305") "CD265 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:O35305") "ODFR (mouse)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mTNFRSF11A") +AnnotationAssertion(Annotation( "UniProtKB:O35305") "osteoclast differentiation factor receptor (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:O35305") "receptor activator of NF-KB (mouse)") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:O35305") Annotation( ) "Rank") +AnnotationAssertion(Annotation( "UniProtKB:O35305") Annotation( ) "Tnfrsf11a") +AnnotationAssertion( "PR:O35305") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "tumor necrosis factor receptor superfamily member 11A (mouse)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (prominin-1 (human)) + +AnnotationAssertion(Annotation( "PRO:CNA") Annotation( "UniProtKB:O43490") "A prominin-1 that is encoded in the genome of human.") +AnnotationAssertion( "UniProtKB:O43490") +AnnotationAssertion(Annotation( "UniProtKB:O43490") "CD133 (human)") +AnnotationAssertion(Annotation( "UniProtKB:O43490") "antigen AC133 (human)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hPROM1") +AnnotationAssertion(Annotation( "UniProtKB:O43490") "prominin-like protein 1 (human)") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:O43490") Annotation( ) "MSTP061") +AnnotationAssertion(Annotation( "UniProtKB:O43490") Annotation( ) "PROM1") +AnnotationAssertion(Annotation( "UniProtKB:O43490") Annotation( ) "PROML1") +AnnotationAssertion( "PR:O43490") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "prominin-1 (human)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (prominin-1 (mouse)) + +AnnotationAssertion(Annotation( "OMA:O54990") Annotation( "PRO:DNx") "A prominin-1 that is encoded in the genome of mouse.") +AnnotationAssertion( "UniProtKB:O54990") +AnnotationAssertion(Annotation( "UniProtKB:O54990") "CD133 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:O54990") "antigen AC133 homolog (mouse)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mPROM1") +AnnotationAssertion(Annotation( "UniProtKB:O54990") "prominin-like protein 1 (mouse)") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:O54990") Annotation( ) "Prom") +AnnotationAssertion(Annotation( "UniProtKB:O54990") Annotation( ) "Prom1") +AnnotationAssertion(Annotation( "UniProtKB:O54990") Annotation( ) "Proml1") +AnnotationAssertion( "PR:O54990") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "prominin-1 (mouse)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (complement component C1q receptor (mouse)) + +AnnotationAssertion(Annotation( "OMA:O89103") Annotation( "PRO:DNx") "A complement component C1q receptor that is encoded in the genome of mouse.") +AnnotationAssertion( "UniProtKB:O89103") +AnnotationAssertion(Annotation( "UniProtKB:O89103") "C1q/MBL/SPA receptor (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:O89103") "C1qR(p) (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:O89103") "C1qRp (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:O89103") "CD93 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:O89103") "Ly-68 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:O89103") "cell surface antigen AA4 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:O89103") "complement component 1 q subcomponent receptor 1 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:O89103") "lymphocyte antigen 68 (mouse)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mCD93") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:O89103") Annotation( ) "Aa4") +AnnotationAssertion(Annotation( "UniProtKB:O89103") Annotation( ) "C1qr1") +AnnotationAssertion(Annotation( "UniProtKB:O89103") Annotation( ) "C1qrp") +AnnotationAssertion(Annotation( "UniProtKB:O89103") Annotation( ) "Cd93") +AnnotationAssertion(Annotation( "UniProtKB:O89103") Annotation( ) "Ly68") +AnnotationAssertion( "PR:O89103") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "complement component C1q receptor (mouse)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (renin (human)) + +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( "UniProtKB:P00797") "A renin that is encoded in the genome of human.") +AnnotationAssertion( "UniProtKB:P00797") +AnnotationAssertion(Annotation( "UniProtKB:P00797") "angiotensinogenase (human)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hREN") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P00797") Annotation( ) "REN") +AnnotationAssertion( "PR:P00797") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "renin (human)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (protein c-Fos (human)) + +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( "UniProtKB:P01100") "A protein c-Fos that is encoded in the genome of human.") +AnnotationAssertion(Annotation(rdfs:label "PR:P01100 located_in GO:0005654") "Reactome:R-HSA-450216") +AnnotationAssertion( "UniProtKB:P01100") +AnnotationAssertion(Annotation( "UniProtKB:P01100") "Fos proto-oncogene, AP-1 transcription factor subunit (human)") +AnnotationAssertion(Annotation( "UniProtKB:P01100") "G0/G1 switch regulatory protein 7 (human)") +AnnotationAssertion(Annotation( "UniProtKB:P01100") "cellular oncogene fos (human)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hFOS") +AnnotationAssertion(Annotation( "UniProtKB:P01100") "proto-oncogene c-Fos (human)") +AnnotationAssertion(Annotation( "UniProtKB:P01100") "transcription factor AP-1 subunit c-Fos (human)") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P01100") Annotation( ) "FOS") +AnnotationAssertion(Annotation( "UniProtKB:P01100") Annotation( ) "G0S7") +AnnotationAssertion( "PR:P01100") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "protein c-Fos (human)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (protein c-Fos (mouse)) + +AnnotationAssertion(Annotation( "OMA:P01101") Annotation( "PRO:DNx") "A protein c-Fos that is encoded in the genome of mouse.") +AnnotationAssertion( "UniProtKB:P01101") +AnnotationAssertion(Annotation( "UniProtKB:P01101") "FBJ osteosarcoma oncogene (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P01101") "cellular oncogene fos (mouse)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mFOS") +AnnotationAssertion(Annotation( "UniProtKB:P01101") "transcription factor AP-1 subunit c-Fos (mouse)") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P01101") Annotation( ) "Fos") +AnnotationAssertion( "PR:P01101") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "protein c-Fos (mouse)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (prolactin (human)) + +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( "UniProtKB:P01236") "A prolactin that is encoded in the genome of human.") +AnnotationAssertion( "UniProtKB:P01236") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hPRL") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P01236") Annotation( ) "PRL") +AnnotationAssertion( "PR:P01236") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "prolactin (human)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (thyroglobulin (human)) + +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( "UniProtKB:P01266") "A thyroglobulin that is encoded in the genome of human.") +AnnotationAssertion( "UniProtKB:P01266") +AnnotationAssertion(Annotation( "UniProtKB:P01266") "Tg (human)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hTG") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P01266") Annotation( ) "TG") +AnnotationAssertion( "PR:P01266") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "thyroglobulin (human)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (insulin gene translation product (human)) + +AnnotationAssertion(Annotation( "PRO:DAN") Annotation( "UniProtKB:P01308") "An insulin gene translation product that is encoded in the genome of human.") +AnnotationAssertion( "UniProtKB:P01308") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hINS") +AnnotationAssertion( "protein") +AnnotationAssertion( "PR:P01308") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "insulin gene translation product (human)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (interleukin-2 receptor subunit alpha (human)) + +AnnotationAssertion(Annotation( "PRO:CNA") Annotation( "UniProtKB:P01589") "An interleukin-2 receptor subunit alpha that is encoded in the genome of human.") +AnnotationAssertion(Annotation( "UniProtKB:P01589") "p55 (human)") +AnnotationAssertion( "UniProtKB:P01589") +AnnotationAssertion(Annotation( "UniProtKB:P01589") "CD25 (human)") +AnnotationAssertion(Annotation( "UniProtKB:P01589") "IL-2 receptor subunit alpha (human)") +AnnotationAssertion(Annotation( "UniProtKB:P01589") "IL-2-RA (human)") +AnnotationAssertion(Annotation( "UniProtKB:P01589") "IL-2R subunit alpha (human)") +AnnotationAssertion(Annotation( "UniProtKB:P01589") "IL2-RA (human)") +AnnotationAssertion(Annotation( "UniProtKB:P01589") "TAC antigen (human)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hIL2RA") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P01589") Annotation( ) "IL2RA") +AnnotationAssertion( "PR:P01589") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "interleukin-2 receptor subunit alpha (human)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (interleukin-2 receptor subunit alpha (mouse)) + +AnnotationAssertion(Annotation( "OMA:P01590") Annotation( "PRO:DNx") "An interleukin-2 receptor subunit alpha that is encoded in the genome of mouse.") +AnnotationAssertion(Annotation( "UniProtKB:P01590") "p55 (mouse)") +AnnotationAssertion( "UniProtKB:P01590") +AnnotationAssertion(Annotation( "UniProtKB:P01590") "CD25 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P01590") "IL-2 receptor subunit alpha (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P01590") "IL-2-RA (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P01590") "IL-2R subunit alpha (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P01590") "IL2-RA (mouse)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mIL2RA") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P01590") Annotation( ) "Il2r") +AnnotationAssertion(Annotation( "UniProtKB:P01590") Annotation( ) "Il2ra") +AnnotationAssertion( "PR:P01590") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "interleukin-2 receptor subunit alpha (mouse)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (T-cell surface glycoprotein CD4 (human)) + +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( "UniProtKB:P01730") "A CD4 molecule that is encoded in the genome of human.") +AnnotationAssertion( "UniProtKB:P01730") +AnnotationAssertion(Annotation( "UniProtKB:P01730") "T-cell surface antigen T4/Leu-3 (human)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hCD4") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P01730") Annotation( ) "CD4") +AnnotationAssertion( "PR:P01730") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "T-cell surface glycoprotein CD4 (human)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (T-cell surface glycoprotein CD8 alpha chain (mouse)) + +AnnotationAssertion(Annotation( "OMA:P01731") Annotation( "PRO:DNx") "A T-cell surface glycoprotein CD8 alpha chain that is encoded in the genome of mouse.") +AnnotationAssertion( "UniProtKB:P01731") +AnnotationAssertion(Annotation( "UniProtKB:P01731") "CD8a (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P01731") "T-cell surface glycoprotein Lyt-2 (mouse)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mCD8A") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P01731") Annotation( ) "Cd8a") +AnnotationAssertion(Annotation( "UniProtKB:P01731") Annotation( ) "Lyt-2") +AnnotationAssertion(Annotation( "UniProtKB:P01731") Annotation( ) "Lyt2") +AnnotationAssertion( "PR:P01731") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "T-cell surface glycoprotein CD8 alpha chain (mouse)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (T-cell surface glycoprotein CD8 alpha chain (human)) + +AnnotationAssertion(Annotation( "PRO:CNA") Annotation( "UniProtKB:P01732") "A T-cell surface glycoprotein CD8 alpha chain that is encoded in the genome of human.") +AnnotationAssertion( "UniProtKB:P01732") +AnnotationAssertion(Annotation( "UniProtKB:P01732") "CD8a (human)") +AnnotationAssertion(Annotation( "UniProtKB:P01732") "T-lymphocyte differentiation antigen T8/Leu-2 (human)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hCD8A") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P01732") Annotation( ) "CD8A") +AnnotationAssertion(Annotation( "UniProtKB:P01732") Annotation( ) "MAL") +AnnotationAssertion( "PR:P01732") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "T-cell surface glycoprotein CD8 alpha chain (human)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (Thy-1 membrane glycoprotein (mouse)) + +AnnotationAssertion(Annotation( "OMA:P01831") Annotation( "PRO:DNx") "A Thy-1 membrane glycoprotein that is encoded in the genome of mouse.") +AnnotationAssertion( "UniProtKB:P01831") +AnnotationAssertion(Annotation( "UniProtKB:P01831") "CD90 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P01831") "Thy-1 antigen (mouse)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mTHY1") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P01831") Annotation( ) "Thy-1") +AnnotationAssertion(Annotation( "UniProtKB:P01831") Annotation( ) "Thy1") +AnnotationAssertion( "PR:P01831") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "Thy-1 membrane glycoprotein (mouse)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (myelin basic protein (human)) + +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( "UniProtKB:P02686") "A myelin basic protein that is encoded in the genome of human.") +AnnotationAssertion(Annotation(rdfs:label "PR:P02686 located_in GO:0005829") "Reactome:R-HSA-9614770") +AnnotationAssertion( "UniProtKB:P02686") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hMBP") +AnnotationAssertion(Annotation( "UniProtKB:P02686") "myelin A1 protein (human)") +AnnotationAssertion(Annotation( "UniProtKB:P02686") "myelin membrane encephalitogenic protein (human)") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P02686") Annotation( ) "MBP") +AnnotationAssertion( "PR:P02686") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "myelin basic protein (human)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (glycophorin-A (human)) + +AnnotationAssertion(Annotation( "PRO:CNA") Annotation( "UniProtKB:P02724") "A glycophorin-A that is encoded in the genome of human.") +AnnotationAssertion( "UniProtKB:P02724") +AnnotationAssertion(Annotation( "UniProtKB:P02724") "CD235a (human)") +AnnotationAssertion(Annotation( "UniProtKB:P02724") "MN sialoglycoprotein (human)") +AnnotationAssertion(Annotation( "UniProtKB:P02724") "PAS-2 (human)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hGYPA") +AnnotationAssertion(Annotation( "UniProtKB:P02724") "sialoglycoprotein alpha (human)") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P02724") Annotation( ) "GPA") +AnnotationAssertion(Annotation( "UniProtKB:P02724") Annotation( ) "GYPA") +AnnotationAssertion( "PR:P02724") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "glycophorin-A (human)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (transferrin receptor protein 1 (human)) + +AnnotationAssertion(Annotation( "PRO:WCB") Annotation( "UniProtKB:P02786") "A transferrin receptor protein 1 that is encoded in the genome of human.") +AnnotationAssertion(Annotation( "UniProtKB:P02786") "TR (human)") +AnnotationAssertion(Annotation( "UniProtKB:P02786") "p90 (human)") +AnnotationAssertion(Annotation(rdfs:label "PR:P02786 located_in GO:0030659") "Reactome:R-HSA-434196") +AnnotationAssertion(Annotation(rdfs:label "PR:P02786 located_in GO:0000139") "Reactome:R-HSA-434330") +AnnotationAssertion(Annotation(rdfs:label "PR:P02786 located_in GO:0030665") "Reactome:R-HSA-8869124") +AnnotationAssertion(Annotation(rdfs:label "PR:P02786 located_in GO:0010008") "Reactome:R-HSA-8961829") +AnnotationAssertion(Annotation(rdfs:label "PR:P02786 located_in GO:0005886") "Reactome:R-HSA-917983") +AnnotationAssertion( "UniProtKB:P02786") +AnnotationAssertion(Annotation( "UniProtKB:P02786") "CD71 (human)") +AnnotationAssertion(Annotation( "UniProtKB:P02786") "T9 (human)") +AnnotationAssertion(Annotation( "UniProtKB:P02786") "TfR (human)") +AnnotationAssertion(Annotation( "UniProtKB:P02786") "TfR1 (human)") +AnnotationAssertion(Annotation( "UniProtKB:P02786") "Trfr (human)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hTFRC") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P02786") Annotation( ) "TFRC") +AnnotationAssertion( "PR:P02786") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "transferrin receptor protein 1 (human)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (lactotransferrin (human)) + +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( "UniProtKB:P02788") "A lactotransferrin that is encoded in the genome of human.") +AnnotationAssertion( "UniProtKB:P02788") +AnnotationAssertion(Annotation( "UniProtKB:P02788") "growth-inhibiting protein 12 (human)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hLTF") +AnnotationAssertion(Annotation( "UniProtKB:P02788") "lactoferrin (human)") +AnnotationAssertion(Annotation( "UniProtKB:P02788") "talalactoferrin (human)") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P02788") Annotation( ) "GIG12") +AnnotationAssertion(Annotation( "UniProtKB:P02788") Annotation( ) "LF") +AnnotationAssertion(Annotation( "UniProtKB:P02788") Annotation( ) "LTF") +AnnotationAssertion( "PR:P02788") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "lactotransferrin (human)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (glial fibrillary acidic protein (mouse)) + +AnnotationAssertion(Annotation( "OMA:P03995") Annotation( "PRO:DNx") "A glial fibrillary acidic protein that is encoded in the genome of mouse.") +AnnotationAssertion( "UniProtKB:P03995") +AnnotationAssertion(Annotation( "UniProtKB:P03995") "GFAP (mouse)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mGFAP") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P03995") Annotation( ) "Gfap") +AnnotationAssertion( "PR:P03995") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "glial fibrillary acidic protein (mouse)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (DNA nucleotidylexotransferase (human)) + +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( "UniProtKB:P04053") "A DNA nucleotidylexotransferase that is encoded in the genome of human.") +AnnotationAssertion(Annotation( "UniProtKB:P04053") "terminal transferase (human)") +AnnotationAssertion( "UniProtKB:P04053") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hDNTT") +AnnotationAssertion(Annotation( "UniProtKB:P04053") "terminal addition enzyme (human)") +AnnotationAssertion(Annotation( "UniProtKB:P04053") "terminal deoxynucleotidyltransferase (human)") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P04053") Annotation( ) "DNTT") +AnnotationAssertion(Annotation( "UniProtKB:P04053") Annotation( ) "TDT") +AnnotationAssertion( "PR:P04053") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "DNA nucleotidylexotransferase (human)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (Thy-1 membrane glycoprotein (human)) + +AnnotationAssertion(Annotation( "PRO:WCB") Annotation( "UniProtKB:P04216") "A Thy-1 membrane glycoprotein that is encoded in the genome of human.") +AnnotationAssertion( "UniProtKB:P04216") +AnnotationAssertion(Annotation( "UniProtKB:P04216") "CD90 (human)") +AnnotationAssertion(Annotation( "UniProtKB:P04216") "CDw90 (human)") +AnnotationAssertion(Annotation( "UniProtKB:P04216") "Thy-1 antigen (human)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hTHY1") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P04216") Annotation( ) "THY1") +AnnotationAssertion( "PR:P04216") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "Thy-1 membrane glycoprotein (human)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (myelin basic protein (mouse)) + +AnnotationAssertion(Annotation( "OMA:P04370") Annotation( "PRO:DNx") "A myelin basic protein that is encoded in the genome of mouse.") +AnnotationAssertion( "UniProtKB:P04370") +AnnotationAssertion(Annotation( "UniProtKB:P04370") "MBP (mouse)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mMBP") +AnnotationAssertion(Annotation( "UniProtKB:P04370") "myelin A1 protein (mouse)") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P04370") Annotation( ) "Mbp") +AnnotationAssertion(Annotation( "UniProtKB:P04370") Annotation( ) "Shi") +AnnotationAssertion( "PR:P04370") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "myelin basic protein (mouse)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (mast/stem cell growth factor receptor Kit (mouse)) + +AnnotationAssertion(Annotation( "OMA:MOUSE17014") Annotation( "PRO:DNx") "A mast/stem cell growth factor receptor that is encoded in the genome of mouse.") +AnnotationAssertion( "UniProtKB:P05532") +AnnotationAssertion(Annotation( "UniProtKB:P05532") "CD117 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P05532") "SCFR (mouse)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mKIT") +AnnotationAssertion(Annotation( "UniProtKB:P05532") "proto-oncogene c-Kit (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P05532") "tyrosine-protein kinase Kit (mouse)") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P05532") Annotation( ) "Kit") +AnnotationAssertion(Annotation( "UniProtKB:P05532") Annotation( ) "Sl") +AnnotationAssertion( "PR:P05532") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "mast/stem cell growth factor receptor Kit (mouse)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (lymphocyte antigen 6A-2/6E-1 (mouse)) + +AnnotationAssertion(Annotation( "PRO:CNA") Annotation( "UniProtKB:P05533") "A lymphocyte antigen 6A-2/6E-1 that is encoded in the genome of mouse.") +AnnotationAssertion(Annotation( "UniProtKB:P05533") "TAP (mouse)") +AnnotationAssertion( "UniProtKB:P05533") +AnnotationAssertion(Annotation( "UniProtKB:P05533") "Ly-6A.2/Ly-6E.1 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P05533") "SCA-1 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P05533") "Stem cell antigen 1 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P05533") "T-cell-activating protein (mouse)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mLy6a") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P05533") Annotation( ) "Ly6") +AnnotationAssertion(Annotation( "UniProtKB:P05533") Annotation( ) "Ly6a") +AnnotationAssertion( "PR:P05533") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "lymphocyte antigen 6A-2/6E-1 (mouse)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (integrin alpha-M (mouse)) + +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( "UniProtKB:P05555") "An integrin alpha-M that is encoded in the genome of mouse.") +AnnotationAssertion( "UniProtKB:P05555") +AnnotationAssertion(Annotation( "UniProtKB:P05555") "CD11 antigen-like family member B (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P05555") "CD11b (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P05555") "CR-3 alpha chain (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P05555") "cell surface glycoprotein MAC-1 subunit alpha (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P05555") "leukocyte adhesion receptor MO1 (mouse)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mITGAM") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P05555") Annotation( ) "Itgam") +AnnotationAssertion( "PR:P05555") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "integrin alpha-M (mouse)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (T-cell surface glycoprotein CD5 (human)) + +AnnotationAssertion(Annotation( "PRO:WCB") Annotation( "UniProtKB:P06127") "A T-cell surface glycoprotein CD5 that is encoded in the genome of human.") +AnnotationAssertion( "UniProtKB:P06127") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hCD5") +AnnotationAssertion(Annotation( "UniProtKB:P06127") "lymphocyte antigen T1/Leu-1 (human)") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P06127") Annotation( ) "CD5") +AnnotationAssertion(Annotation( "UniProtKB:P06127") Annotation( ) "LEU1") +AnnotationAssertion( "PR:P06127") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "T-cell surface glycoprotein CD5 (human)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (T-cell surface glycoprotein CD4 (mouse)) + +AnnotationAssertion(Annotation( "OMA:P06332") Annotation( "PRO:DNx") "A CD4 molecule that is encoded in the genome of mouse.") +AnnotationAssertion( "UniProtKB:P06332") +AnnotationAssertion(Annotation( "UniProtKB:P06332") "CD4 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P06332") "T-cell differentiation antigen L3T4 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P06332") "T-cell surface antigen T4/Leu-3 (mouse)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mCD4") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P06332") Annotation( ) "Cd4") +AnnotationAssertion( "PR:P06332") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "T-cell surface glycoprotein CD4 (mouse)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (T-cell surface antigen CD2 (human)) + +AnnotationAssertion(Annotation( "PRO:CNA") Annotation( "UniProtKB:P06729") "A CD2 molecule that is encoded in the genome of human.") +AnnotationAssertion( "UniProtKB:P06729") +AnnotationAssertion(Annotation( "UniProtKB:P06729") "LFA-2 (human)") +AnnotationAssertion(Annotation( "UniProtKB:P06729") "LFA-3 receptor (human)") +AnnotationAssertion(Annotation( "UniProtKB:P06729") "T-cell surface antigen T11/Leu-5 (human)") +AnnotationAssertion(Annotation( "UniProtKB:P06729") "erythrocyte receptor (human)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hCD2") +AnnotationAssertion(Annotation( "UniProtKB:P06729") "rosette receptor (human)") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P06729") Annotation( ) "CD2") +AnnotationAssertion(Annotation( "UniProtKB:P06729") Annotation( ) "SRBC") +AnnotationAssertion( "PR:P06729") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "T-cell surface antigen CD2 (human)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (low affinity immunoglobulin epsilon Fc receptor (human)) + +AnnotationAssertion(Annotation( "PRO:WCB") Annotation( "UniProtKB:P06734") "A low affinity immunoglobulin epsilon Fc receptor that is encoded in the genome of human.") +AnnotationAssertion(Annotation(rdfs:label "PR:P06734 located_in GO:0005886") "Reactome:R-HSA-2127280") +AnnotationAssertion( "UniProtKB:P06734") +AnnotationAssertion(Annotation( "UniProtKB:P06734") "BLAST-2 (human)") +AnnotationAssertion(Annotation( "UniProtKB:P06734") "C-type lectin domain family 4 member J (human)") +AnnotationAssertion(Annotation( "UniProtKB:P06734") "CD23 (human)") +AnnotationAssertion(Annotation( "UniProtKB:P06734") "Fc-epsilon-RII (human)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hFCER2") +AnnotationAssertion(Annotation( "UniProtKB:P06734") "immunoglobulin E-binding factor (human)") +AnnotationAssertion(Annotation( "UniProtKB:P06734") "lymphocyte IgE receptor (human)") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P06734") Annotation( ) "CD23A") +AnnotationAssertion(Annotation( "UniProtKB:P06734") Annotation( ) "CLEC4J") +AnnotationAssertion(Annotation( "UniProtKB:P06734") Annotation( ) "FCE2") +AnnotationAssertion(Annotation( "UniProtKB:P06734") Annotation( ) "FCER2") +AnnotationAssertion(Annotation( "UniProtKB:P06734") Annotation( ) "IGEBF") +AnnotationAssertion( "PR:P06734") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "low affinity immunoglobulin epsilon Fc receptor (human)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (receptor-type tyrosine-protein phosphatase C (mouse)) + +AnnotationAssertion(Annotation( "OMA:P06800") Annotation( "PRO:DNx") "A receptor-type tyrosine-protein phosphatase C that is encoded in the genome of mouse.") +AnnotationAssertion( "UniProtKB:P06800") +AnnotationAssertion(Annotation( "UniProtKB:P06800") "CD45 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P06800") "L-CA (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P06800") "T200 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P06800") "leukocyte common antigen (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P06800") "lymphocyte antigen 5 (mouse)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mPTPRC") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P06800") Annotation( ) "Ly-5") +AnnotationAssertion(Annotation( "UniProtKB:P06800") Annotation( ) "Ptprc") +AnnotationAssertion( "PR:P06800") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "receptor-type tyrosine-protein phosphatase C (mouse)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (prolactin (mouse)) + +AnnotationAssertion(Annotation( "OMA:P06879") Annotation( "PRO:DNx") "A prolactin that is encoded in the genome of mouse.") +AnnotationAssertion( "UniProtKB:P06879") +AnnotationAssertion(Annotation( "UniProtKB:P06879") "PRL (mouse)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mPRL") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P06879") Annotation( ) "Prl") +AnnotationAssertion( "PR:P06879") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "prolactin (mouse)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (macrophage colony-stimulating factor 1 receptor (human)) + +AnnotationAssertion(Annotation( "PRO:WCB") Annotation( "UniProtKB:P07333") "A macrophage colony-stimulating factor 1 receptor that is encoded in the genome of human.") +AnnotationAssertion( "DTO:03100090") +AnnotationAssertion( "UniProtKB:P07333") +AnnotationAssertion(Annotation( "UniProtKB:P07333") "CD115 (human)") +AnnotationAssertion(Annotation( "UniProtKB:P07333") "CSF-1 receptor (human)") +AnnotationAssertion(Annotation( "UniProtKB:P07333") "CSF-1-R (human)") +AnnotationAssertion(Annotation( "UniProtKB:P07333") "CSF-1R (human)") +AnnotationAssertion(Annotation( "UniProtKB:P07333") "M-CSF-R (human)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hCSF1R") +AnnotationAssertion(Annotation( "UniProtKB:P07333") "proto-oncogene c-Fms (human)") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P07333") Annotation( ) "CSF1R") +AnnotationAssertion(Annotation( "UniProtKB:P07333") Annotation( ) "FMS") +AnnotationAssertion( "PR:P07333") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "macrophage colony-stimulating factor 1 receptor (human)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (T-cell surface glycoprotein CD3 epsilon chain (human)) + +AnnotationAssertion(Annotation( "PRO:CNA") Annotation( "UniProtKB:P07766") "A CD3 epsilon that is encoded in the genome of human.") +AnnotationAssertion( "UniProtKB:P07766") +AnnotationAssertion(Annotation( "UniProtKB:P07766") "CD3e (human)") +AnnotationAssertion(Annotation( "UniProtKB:P07766") "T-cell surface antigen T3/Leu-4 epsilon chain (human)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hCD3E") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P07766") Annotation( ) "CD3E") +AnnotationAssertion(Annotation( "UniProtKB:P07766") Annotation( ) "T3E") +AnnotationAssertion( "PR:P07766") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "T-cell surface glycoprotein CD3 epsilon chain (human)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (lactotransferrin (mouse)) + +AnnotationAssertion(Annotation( "OMA:P08071") Annotation( "PRO:DNx") "A lactotransferrin that is encoded in the genome of mouse.") +AnnotationAssertion( "UniProtKB:P08071") +AnnotationAssertion(Annotation( "UniProtKB:P08071") "lactoferrin (mouse)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mLTF") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P08071") Annotation( ) "Ltf") +AnnotationAssertion( "PR:P08071") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "lactotransferrin (mouse)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (low affinity immunoglobulin gamma Fc region receptor II (mouse)) + +AnnotationAssertion(Annotation( "PRO:CNA") Annotation( "UniProtKB:P08101") "A low affinity immunoglobulin gamma Fc region receptor II that is encoded in the genome of mouse.") +AnnotationAssertion( "UniProtKB:P08101") +AnnotationAssertion(Annotation( "UniProtKB:P08101") "CD32 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P08101") "Fc gamma receptor IIB (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P08101") "Fc-gamma RII (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P08101") "Fc-gamma-RIIB (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P08101") "FcRII (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P08101") "IgG Fc receptor II beta (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P08101") "lymphocyte antigen 17 (mouse)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mFcgr2") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P08101") Annotation( ) "Fcgr2") +AnnotationAssertion(Annotation( "UniProtKB:P08101") Annotation( ) "Fcgr2b") +AnnotationAssertion(Annotation( "UniProtKB:P08101") Annotation( ) "Ly-17") +AnnotationAssertion( "PR:P08101") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "low affinity immunoglobulin gamma Fc region receptor II (mouse)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (neprilysin (human)) + +AnnotationAssertion(Annotation( "PRO:WCB") Annotation( "UniProtKB:P08473") "A neprilysin that is encoded in the genome of human.") +AnnotationAssertion( "UniProtKB:P08473") +AnnotationAssertion(Annotation( "UniProtKB:P08473") "CALLA (human)") +AnnotationAssertion(Annotation( "UniProtKB:P08473") "CD10 (human)") +AnnotationAssertion(Annotation( "UniProtKB:P08473") "NEP (human)") +AnnotationAssertion(Annotation( "UniProtKB:P08473") "SFE (human)") +AnnotationAssertion(Annotation( "UniProtKB:P08473") "atriopeptidase (human)") +AnnotationAssertion(Annotation( "UniProtKB:P08473") "common acute lymphocytic leukemia antigen (human)") +AnnotationAssertion(Annotation( "UniProtKB:P08473") "enkephalinase (human)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hMME") +AnnotationAssertion(Annotation( "UniProtKB:P08473") "neutral endopeptidase (human)") +AnnotationAssertion(Annotation( "UniProtKB:P08473") "neutral endopeptidase 24.11 (human)") +AnnotationAssertion(Annotation( "UniProtKB:P08473") "skin fibroblast elastase (human)") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P08473") Annotation( ) "EPN") +AnnotationAssertion(Annotation( "UniProtKB:P08473") Annotation( ) "MME") +AnnotationAssertion( "PR:P08473") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "neprilysin (human)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (low affinity immunoglobulin gamma Fc region receptor III (mouse)) + +AnnotationAssertion(Annotation( "PRO:CNA") Annotation( "UniProtKB:P08508") "A low affinity immunoglobulin gamma Fc region receptor III that is encoded in the genome of mouse.") +AnnotationAssertion( "UniProtKB:P08508") +AnnotationAssertion(Annotation( "UniProtKB:P08508") "CD16 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P08508") "Fc-gamma RIII (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P08508") "FcRIII (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P08508") "IgG Fc receptor III (mouse)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mFcgr3") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P08508") Annotation( ) "Fcgr3") +AnnotationAssertion( "PR:P08508") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "low affinity immunoglobulin gamma Fc region receptor III (mouse)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (integrin alpha-IIb (human)) + +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( "UniProtKB:P08514") "An integrin alpha-IIb that is encoded in the genome of human.") +AnnotationAssertion( "UniProtKB:P08514") +AnnotationAssertion(Annotation( "UniProtKB:P08514") "CD41 (human)") +AnnotationAssertion(Annotation( "UniProtKB:P08514") "GPIIb (human)") +AnnotationAssertion(Annotation( "UniProtKB:P08514") "GPalpha IIb (human)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hITGA2B") +AnnotationAssertion(Annotation( "UniProtKB:P08514") "platelet membrane glycoprotein IIb (human)") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P08514") Annotation( ) "GP2B") +AnnotationAssertion(Annotation( "UniProtKB:P08514") Annotation( ) "ITGA2B") +AnnotationAssertion(Annotation( "UniProtKB:P08514") Annotation( ) "ITGAB") +AnnotationAssertion( "PR:P08514") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "integrin alpha-IIb (human)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (monocyte differentiation antigen CD14 (human)) + +AnnotationAssertion(Annotation( "PRO:WCB") Annotation( "UniProtKB:P08571") "A CD14 molecule that is encoded in the genome of human.") +AnnotationAssertion( "UniProtKB:P08571") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hCD14") +AnnotationAssertion(Annotation( "UniProtKB:P08571") "myeloid cell-specific leucine-rich glycoprotein (human)") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P08571") Annotation( ) "CD14") +AnnotationAssertion( "PR:P08571") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "monocyte differentiation antigen CD14 (human)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (receptor-type tyrosine-protein phosphatase C (human)) + +AnnotationAssertion(Annotation( "PRO:CNA") Annotation( "UniProtKB:P08575") "A receptor-type tyrosine-protein phosphatase C that is encoded in the genome of human.") +AnnotationAssertion( "UniProtKB:P08575") +AnnotationAssertion(Annotation( "UniProtKB:P08575") "L-CA (human)") +AnnotationAssertion(Annotation( "UniProtKB:P08575") "T200 (human)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hPTPRC") +AnnotationAssertion(Annotation( "UniProtKB:P08575") "leukocyte common antigen (human)") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P08575") Annotation( ) "CD45") +AnnotationAssertion(Annotation( "UniProtKB:P08575") Annotation( ) "PTPRC") +AnnotationAssertion( "PR:P08575") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "receptor-type tyrosine-protein phosphatase C (human)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (receptor-type tyrosine-protein phosphatase C isoform CD45RABC (human)) + +AnnotationAssertion(Annotation( "PRO:DAN") "A receptor-type tyrosine-protein phosphatase C isoform CD45RABC that is encoded in the genome of human.") +AnnotationAssertion( "UniProtKB:P08575-3") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hPTPRC/iso:CD45RABC") +AnnotationAssertion( "protein") +AnnotationAssertion( "PR:P08575-3") +AnnotationAssertion(rdfs:comment "Category=organism-sequence.") +AnnotationAssertion(rdfs:label "receptor-type tyrosine-protein phosphatase C isoform CD45RABC (human)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (receptor-type tyrosine-protein phosphatase C isoform CD45RA (human)) + +AnnotationAssertion(Annotation( "GOC:add") Annotation( "PRO:ADD") Annotation( "PRO:DAN") "A receptor-type tyrosine-protein phosphatase C isoform CD45RA that is encoded in the genome of human.") +AnnotationAssertion( "UniProtKB:P08575-8") +AnnotationAssertion( "CD45RA (human)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hPTPRC/iso:CD45RA") +AnnotationAssertion( "protein") +AnnotationAssertion( "PR:P08575-8") +AnnotationAssertion(rdfs:comment "Category=organism-sequence. Requested by=CL.") +AnnotationAssertion(rdfs:label "receptor-type tyrosine-protein phosphatase C isoform CD45RA (human)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (T-cell surface antigen CD2 (mouse)) + +AnnotationAssertion(Annotation( "OMA:P08920") Annotation( "PRO:DNx") "A CD2 molecule that is encoded in the genome of mouse.") +AnnotationAssertion( "UniProtKB:P08920") +AnnotationAssertion(Annotation( "UniProtKB:P08920") "CD2 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P08920") "LFA-2 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P08920") "LFA-3 receptor (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P08920") "T-cell surface antigen T11/Leu-5 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P08920") "lymphocyte antigen 37 (mouse)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mCD2") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P08920") Annotation( ) "Cd2") +AnnotationAssertion(Annotation( "UniProtKB:P08920") Annotation( ) "Ly-37") +AnnotationAssertion( "PR:P08920") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "T-cell surface antigen CD2 (mouse)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (CD48 antigen (human)) + +AnnotationAssertion(Annotation( "PRO:WCB") Annotation( "UniProtKB:P09326") "A CD48 molecule that is encoded in the genome of human.") +AnnotationAssertion( "UniProtKB:P09326") +AnnotationAssertion(Annotation( "UniProtKB:P09326") "B-lymphocyte activation marker BLAST-1 (human)") +AnnotationAssertion(Annotation( "UniProtKB:P09326") "BCM1 surface antigen (human)") +AnnotationAssertion(Annotation( "UniProtKB:P09326") "SLAM family member 2 (human)") +AnnotationAssertion(Annotation( "UniProtKB:P09326") "SLAMF2 (human)") +AnnotationAssertion(Annotation( "UniProtKB:P09326") "TCT.1 (human)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hCD48") +AnnotationAssertion(Annotation( "UniProtKB:P09326") "leukocyte antigen MEM-102 (human)") +AnnotationAssertion(Annotation( "UniProtKB:P09326") "signaling lymphocytic activation molecule 2 (human)") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P09326") Annotation( ) "BCM1") +AnnotationAssertion(Annotation( "UniProtKB:P09326") Annotation( ) "BLAST1") +AnnotationAssertion(Annotation( "UniProtKB:P09326") Annotation( ) "CD48") +AnnotationAssertion( "PR:P09326") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "CD48 antigen (human)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (T-cell antigen CD7 (human)) + +AnnotationAssertion(Annotation( "PRO:WCB") Annotation( "UniProtKB:P09564") "A CD7 molecule that is encoded in the genome of human.") +AnnotationAssertion( "UniProtKB:P09564") +AnnotationAssertion(Annotation( "UniProtKB:P09564") "GP40 (human)") +AnnotationAssertion(Annotation( "UniProtKB:P09564") "T-cell leukemia antigen (human)") +AnnotationAssertion(Annotation( "UniProtKB:P09564") "T-cell surface antigen Leu-9 (human)") +AnnotationAssertion(Annotation( "UniProtKB:P09564") "TP41 (human)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hCD7") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P09564") Annotation( ) "CD7") +AnnotationAssertion( "PR:P09564") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "T-cell antigen CD7 (human)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (macrophage colony-stimulating factor 1 receptor (mouse)) + +AnnotationAssertion(Annotation( "OMA:P09581") Annotation( "PRO:DNx") "A macrophage colony-stimulating factor 1 receptor that is encoded in the genome of mouse.") +AnnotationAssertion( "UniProtKB:P09581") +AnnotationAssertion(Annotation( "UniProtKB:P09581") "CD115 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P09581") "CSF-1 receptor (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P09581") "CSF-1-R (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P09581") "CSF-1R (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P09581") "M-CSF-R (mouse)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mCSF1R") +AnnotationAssertion(Annotation( "UniProtKB:P09581") "proto-oncogene c-Fms (mouse)") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P09581") Annotation( ) "Csf1r") +AnnotationAssertion(Annotation( "UniProtKB:P09581") Annotation( ) "Csfmr") +AnnotationAssertion(Annotation( "UniProtKB:P09581") Annotation( ) "Fms") +AnnotationAssertion( "PR:P09581") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "macrophage colony-stimulating factor 1 receptor (mouse)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (DNA nucleotidylexotransferase (mouse)) + +AnnotationAssertion(Annotation( "OMA:P09838") Annotation( "PRO:DNx") "A DNA nucleotidylexotransferase that is encoded in the genome of mouse.") +AnnotationAssertion( "UniProtKB:P09838") +AnnotationAssertion(Annotation( "UniProtKB:P09838") "TDT (mouse)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mDNTT") +AnnotationAssertion(Annotation( "UniProtKB:P09838") "terminal addition enzyme (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P09838") "terminal deoxynucleotidyltransferase (mouse)") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P09838") Annotation( ) "Dntt") +AnnotationAssertion(Annotation( "UniProtKB:P09838") Annotation( ) "Tdt") +AnnotationAssertion(Annotation( "UniProtKB:P09838") "terminal transferase (mouse)") +AnnotationAssertion( "PR:P09838") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "DNA nucleotidylexotransferase (mouse)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (lymphocyte antigen 6C2 (mouse)) + +AnnotationAssertion(Annotation( "PRO:CNA") Annotation( "UniProtKB:P0CW03") "A lymphocyte antigen 6C2 that is encoded in the genome of mouse.") +AnnotationAssertion( "UniProtKB:P0CW03") +AnnotationAssertion(Annotation( "UniProtKB:P0CW03") "Ly-6C2 (mouse)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mLy6c2") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P0CW03") Annotation( ) "Ly6c") +AnnotationAssertion(Annotation( "UniProtKB:P0CW03") Annotation( ) "Ly6c2") +AnnotationAssertion( "PR:P0CW03") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "lymphocyte antigen 6C2 (mouse)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (mast/stem cell growth factor receptor Kit (human)) + +AnnotationAssertion(Annotation( "PRO:WCB") Annotation( "UniProtKB:P10721") "A mast/stem cell growth factor receptor that is encoded in the genome of human.") +AnnotationAssertion( "DTO:03100231") +AnnotationAssertion( "UniProtKB:P10721") +AnnotationAssertion(Annotation( "UniProtKB:P10721") "CD117 (human)") +AnnotationAssertion(Annotation( "UniProtKB:P10721") "PBT (human)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hKIT") +AnnotationAssertion(Annotation( "UniProtKB:P10721") "p145 c-kit (human)") +AnnotationAssertion(Annotation( "UniProtKB:P10721") "piebald trait protein (human)") +AnnotationAssertion(Annotation( "UniProtKB:P10721") "proto-oncogene c-Kit (human)") +AnnotationAssertion(Annotation( "UniProtKB:P10721") "tyrosine-protein kinase Kit (human)") +AnnotationAssertion(Annotation( "UniProtKB:P10721") "v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog (human)") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P10721") Annotation( ) "KIT") +AnnotationAssertion(Annotation( "UniProtKB:P10721") Annotation( ) "SCFR") +AnnotationAssertion( "PR:P10721") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "mast/stem cell growth factor receptor Kit (human)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (monocyte differentiation antigen CD14 (mouse)) + +AnnotationAssertion(Annotation( "OMA:P10810") Annotation( "PRO:WCB") "A CD14 molecule that is encoded in the genome of mouse.") +AnnotationAssertion( "UniProtKB:P10810") +AnnotationAssertion(Annotation( "UniProtKB:P10810") "CD14 (mouse)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mCD14") +AnnotationAssertion(Annotation( "UniProtKB:P10810") "myeloid cell-specific leucine-rich glycoprotein (mouse)") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P10810") Annotation( ) "Cd14") +AnnotationAssertion( "PR:P10810") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "monocyte differentiation antigen CD14 (mouse)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (integrin alpha-M (human)) + +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( "UniProtKB:P11215") "An integrin alpha-M that is encoded in the genome of human.") +AnnotationAssertion( "UniProtKB:P11215") +AnnotationAssertion(Annotation( "UniProtKB:P11215") "CD11 antigen-like family member B (human)") +AnnotationAssertion(Annotation( "UniProtKB:P11215") "CR-3 alpha chain (human)") +AnnotationAssertion(Annotation( "UniProtKB:P11215") "cell surface glycoprotein MAC-1 subunit alpha (human)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hITGAM") +AnnotationAssertion(Annotation( "UniProtKB:P11215") "leukocyte adhesion receptor MO1 (human)") +AnnotationAssertion(Annotation( "UniProtKB:P11215") "neutrophil adherence receptor (human)") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P11215") Annotation( ) "CD11B") +AnnotationAssertion(Annotation( "UniProtKB:P11215") Annotation( ) "CR3A") +AnnotationAssertion(Annotation( "UniProtKB:P11215") Annotation( ) "ITGAM") +AnnotationAssertion( "PR:P11215") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "integrin alpha-M (human)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (B-lymphocyte antigen CD20 (human)) + +AnnotationAssertion(Annotation( "PRO:WCB") Annotation( "UniProtKB:P11836") "A membrane-spanning 4-domains subfamily A member 1 that is encoded in the genome of human.") +AnnotationAssertion( "UniProtKB:P11836") +AnnotationAssertion(Annotation( "UniProtKB:P11836") "B-lymphocyte surface antigen B1 (human)") +AnnotationAssertion(Annotation( "UniProtKB:P11836") "Bp35 (human)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hMS4A1") +AnnotationAssertion(Annotation( "UniProtKB:P11836") "leukocyte surface antigen Leu-16 (human)") +AnnotationAssertion(Annotation( "UniProtKB:P11836") "membrane-spanning 4-domains subfamily A member 1 (human)") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P11836") Annotation( ) "CD20") +AnnotationAssertion(Annotation( "UniProtKB:P11836") Annotation( ) "MS4A1") +AnnotationAssertion( "PR:P11836") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "B-lymphocyte antigen CD20 (human)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (protein c-Fos (chicken)) + +AnnotationAssertion(Annotation( "OMA:P11939") Annotation( "PRO:DNx") "A protein c-Fos that is encoded in the genome of chicken.") +AnnotationAssertion( "UniProtKB:P11939") +AnnotationAssertion(Annotation( "UniProtKB:P11939") "cellular oncogene fos (chicken)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "chick-FOS") +AnnotationAssertion(Annotation( "UniProtKB:P11939") "transcription factor AP-1 subunit c-Fos (chicken)") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P11939") Annotation( ) "FOS") +AnnotationAssertion( "PR:P11939") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "protein c-Fos (chicken)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (immunoglobulin iota chain (human)) + +AnnotationAssertion(Annotation( "PRO:WCB") Annotation( "UniProtKB:P12018") "An immunoglobulin iota chain that is encoded in the genome of human.") +AnnotationAssertion( "UniProtKB:P12018") +AnnotationAssertion(Annotation( "UniProtKB:P12018") "CD179 antigen-like family member A (human)") +AnnotationAssertion(Annotation( "UniProtKB:P12018") "CD179a (human)") +AnnotationAssertion(Annotation( "UniProtKB:P12018") "V(pre)B protein (human)") +AnnotationAssertion(Annotation( "UniProtKB:P12018") "VpreB protein (human)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hVPREB1") +AnnotationAssertion(Annotation( "UniProtKB:P12018") "protein VPreB1 (human)") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P12018") Annotation( ) "VPREB") +AnnotationAssertion(Annotation( "UniProtKB:P12018") Annotation( ) "VPREB1") +AnnotationAssertion( "PR:P12018") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "immunoglobulin iota chain (human)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (T-cell surface glycoprotein CD5 (mouse)) + +AnnotationAssertion(Annotation( "OMA:P13379") Annotation( "PRO:DNx") "A T-cell surface glycoprotein CD5 that is encoded in the genome of mouse.") +AnnotationAssertion( "UniProtKB:P13379") +AnnotationAssertion(Annotation( "UniProtKB:P13379") "CD5 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P13379") "Lyt-1 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P13379") "lymphocyte antigen 1 (mouse)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mCD5") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P13379") Annotation( ) "Cd5") +AnnotationAssertion(Annotation( "UniProtKB:P13379") Annotation( ) "Ly-1") +AnnotationAssertion( "PR:P13379") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "T-cell surface glycoprotein CD5 (mouse)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (neural cell adhesion molecule 1 (chicken)) + +AnnotationAssertion(Annotation( "OMA:P13590") Annotation( "PRO:CNA") "A neural cell adhesion molecule 1 that is encoded in the genome of chicken.") +AnnotationAssertion( "UniProtKB:P13590") +AnnotationAssertion(Annotation( "UniProtKB:P13590") "N-CAM-1 (chicken)") +AnnotationAssertion(Annotation( "UniProtKB:P13590") "NCAM-1 (chicken)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "chick-NCAM1") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P13590") Annotation( ) "NCAM1") +AnnotationAssertion( "PR:P13590") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "neural cell adhesion molecule 1 (chicken)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (neural cell adhesion molecule 1 (human)) + +AnnotationAssertion(Annotation( "PRO:CNA") Annotation( "UniProtKB:P13591") "A neural cell adhesion molecule 1 that is encoded in the genome of human.") +AnnotationAssertion( "UniProtKB:P13591") +AnnotationAssertion(Annotation( "UniProtKB:P13591") "CD56 (human)") +AnnotationAssertion(Annotation( "UniProtKB:P13591") "N-CAM-1 (human)") +AnnotationAssertion(Annotation( "UniProtKB:P13591") "NCAM-1 (human)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hNCAM1") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P13591") Annotation( ) "NCAM") +AnnotationAssertion(Annotation( "UniProtKB:P13591") Annotation( ) "NCAM1") +AnnotationAssertion( "PR:P13591") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "neural cell adhesion molecule 1 (human)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (neural cell adhesion molecule 1 (mouse)) + +AnnotationAssertion(Annotation( "OMA:P13595") Annotation( "PRO:DNx") "A neural cell adhesion molecule 1 that is encoded in the genome of mouse.") +AnnotationAssertion( "UniProtKB:P13595") +AnnotationAssertion(Annotation( "UniProtKB:P13595") "CD56 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P13595") "N-CAM-1 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P13595") "NCAM-1 (mouse)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mNCAM1") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P13595") Annotation( ) "Ncam") +AnnotationAssertion(Annotation( "UniProtKB:P13595") Annotation( ) "Ncam1") +AnnotationAssertion( "PR:P13595") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "neural cell adhesion molecule 1 (mouse)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (tartrate-resistant acid phosphatase type 5 (human)) + +AnnotationAssertion(Annotation( "PRO:WCB") Annotation( "UniProtKB:P13686") "A tartrate-resistant acid phosphatase type 5 that is encoded in the genome of human.") +AnnotationAssertion( "UniProtKB:P13686") +AnnotationAssertion(Annotation( "UniProtKB:P13686") "TR-AP (human)") +AnnotationAssertion(Annotation( "UniProtKB:P13686") "TrATPase (human)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hACP5") +AnnotationAssertion(Annotation( "UniProtKB:P13686") "tartrate-resistant acid ATPase (human)") +AnnotationAssertion(Annotation( "UniProtKB:P13686") "type 5 acid phosphatase (human)") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P13686") Annotation( ) "ACP5") +AnnotationAssertion( "PR:P13686") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "tartrate-resistant acid phosphatase type 5 (human)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (glial fibrillary acidic protein (human)) + +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( "UniProtKB:P14136") "A glial fibrillary acidic protein that is encoded in the genome of human.") +AnnotationAssertion(Annotation(rdfs:label "PR:P14136 located_in GO:0005829") "Reactome:R-HSA-1253311") +AnnotationAssertion(Annotation(rdfs:label "PR:P14136 located_in GO:0005765") "Reactome:R-HSA-9625195") +AnnotationAssertion( "UniProtKB:P14136") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hGFAP") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P14136") Annotation( ) "GFAP") +AnnotationAssertion( "PR:P14136") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "glial fibrillary acidic protein (human)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (prolactin (chicken)) + +AnnotationAssertion(Annotation( "OMA:P14676") Annotation( "PANTHER:PTHR11417:SF4") Annotation( "PRO:DNx") "A prolactin that is encoded in the genome of chicken.") +AnnotationAssertion( "UniProtKB:P14676") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "chick-PRL") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P14676") Annotation( ) "PRL") +AnnotationAssertion( "PR:P14676") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "prolactin (chicken)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (CD44 antigen (mouse)) + +AnnotationAssertion(Annotation( "OMA:P15379") Annotation( "PRO:WCB") "A CD44 molecule that is encoded in the genome of mouse.") +AnnotationAssertion( "UniProtKB:P15379") +AnnotationAssertion(Annotation( "UniProtKB:P15379") "CD44 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P15379") "ECMR-III (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P15379") "GP90 lymphocyte homing/adhesion receptor (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P15379") "HUTCH-I (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P15379") "PGP-1 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P15379") "PGP-I (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P15379") "extracellular matrix receptor III (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P15379") "hermes antigen (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P15379") "hyaluronate receptor (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P15379") "lymphocyte antigen 24 (mouse)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mCD44") +AnnotationAssertion(Annotation( "UniProtKB:P15379") "phagocytic glycoprotein 1 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P15379") "phagocytic glycoprotein I (mouse)") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P15379") Annotation( ) "Cd44") +AnnotationAssertion(Annotation( "UniProtKB:P15379") Annotation( ) "Ly-24") +AnnotationAssertion( "PR:P15379") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "CD44 antigen (mouse)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (B-lymphocyte antigen CD19 (human)) + +AnnotationAssertion( "A CD19 molecule that is encoded in the genome of human.") +AnnotationAssertion( "UniProtKB:P15391") +AnnotationAssertion(Annotation( "UniProtKB:P15391") "B-lymphocyte surface antigen B4 (human)") +AnnotationAssertion(Annotation( "UniProtKB:P15391") "T-cell surface antigen Leu-12 (human)") +AnnotationAssertion(Annotation( "UniProtKB:P15391") "differentiation antigen CD19 (human)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hCD19") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P15391") Annotation( ) "CD19") +AnnotationAssertion( "PR:P15391") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "B-lymphocyte antigen CD19 (human)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (leukosialin (mouse)) + +AnnotationAssertion(Annotation( "OMA:P15702") Annotation( "PRO:DNx") "A leukosialin that is encoded in the genome of mouse.") +AnnotationAssertion( "UniProtKB:P15702") +AnnotationAssertion(Annotation( "UniProtKB:P15702") "B-cell differentiation antigen LP-3 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P15702") "CD43 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P15702") "Ly-48 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P15702") "leukocyte sialoglycoprotein (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P15702") "lymphocyte antigen 48 (mouse)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mSPN") +AnnotationAssertion(Annotation( "UniProtKB:P15702") "sialophorin (mouse)") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P15702") Annotation( ) "Spn") +AnnotationAssertion( "PR:P15702") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "leukosialin (mouse)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (myelin basic protein (chicken)) + +AnnotationAssertion(Annotation( "PANTHER:PTHR11429:SF0") Annotation( "PRO:DNx") "A myelin basic protein that is encoded in the genome of chicken.") +AnnotationAssertion( "UniProtKB:P15720") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "chick-MBP") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P15720") Annotation( ) "MBP") +AnnotationAssertion( "PR:P15720") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "myelin basic protein (chicken)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (immunoglobulin lambda-like polypeptide 1 (human)) + +AnnotationAssertion(Annotation( "PRO:WCB") Annotation( "UniProtKB:P15814") "An immunoglobulin lambda-like polypeptide 1 that is encoded in the genome of human.") +AnnotationAssertion( "UniProtKB:P15814") +AnnotationAssertion(Annotation( "UniProtKB:P15814") "CD179 antigen-like family member B (human)") +AnnotationAssertion(Annotation( "UniProtKB:P15814") "CD179b (human)") +AnnotationAssertion(Annotation( "UniProtKB:P15814") "Ig lambda-5 (human)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hIGLL1") +AnnotationAssertion(Annotation( "UniProtKB:P15814") "immunoglobulin omega polypeptide (human)") +AnnotationAssertion(Annotation( "UniProtKB:P15814") "immunoglobulin-related protein 14.1 (human)") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P15814") Annotation( ) "IGL1") +AnnotationAssertion(Annotation( "UniProtKB:P15814") Annotation( ) "IGLL1") +AnnotationAssertion( "PR:P15814") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "immunoglobulin lambda-like polypeptide 1 (human)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (V(D)J recombination-activating protein 1 (human)) + +AnnotationAssertion(Annotation( "PRO:CNA") Annotation( "UniProtKB:P15918") "A V(D)J recombination-activating protein 1 that is encoded in the genome of human.") +AnnotationAssertion(Annotation(rdfs:label "PR:P15918 located_in GO:0005654") "Reactome:R-HSA-5692681") +AnnotationAssertion( "UniProtKB:P15918") +AnnotationAssertion(Annotation( "UniProtKB:P15918") "RAG-1 (human)") +AnnotationAssertion(Annotation( "UniProtKB:P15918") "RING finger protein 74 (human)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hRAG1") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P15918") Annotation( ) "RAG1") +AnnotationAssertion(Annotation( "UniProtKB:P15918") Annotation( ) "RNF74") +AnnotationAssertion( "PR:P15918") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "V(D)J recombination-activating protein 1 (human)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (V(D)J recombination-activating protein 1 (mouse)) + +AnnotationAssertion(Annotation( "OMA:P15919") Annotation( "PRO:DNx") "A V(D)J recombination-activating protein 1 that is encoded in the genome of mouse.") +AnnotationAssertion( "UniProtKB:P15919") +AnnotationAssertion(Annotation( "UniProtKB:P15919") "RAG-1 (mouse)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mRAG1") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P15919") Annotation( ) "Rag1") +AnnotationAssertion( "PR:P15919") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "V(D)J recombination-activating protein 1 (mouse)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (erythroid transcription factor (human)) + +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( "UniProtKB:P15976") "An erythroid transcription factor that is encoded in the genome of human.") +AnnotationAssertion(Annotation( "UniProtKB:P15976") "GF-1 (human)") +AnnotationAssertion(Annotation(rdfs:label "PR:P15976 located_in GO:0005654") "Reactome:R-HSA-996772") +AnnotationAssertion( "UniProtKB:P15976") +AnnotationAssertion(Annotation( "UniProtKB:P15976") "GATA-1 (human)") +AnnotationAssertion(Annotation( "UniProtKB:P15976") "GATA-binding factor 1 (human)") +AnnotationAssertion(Annotation( "UniProtKB:P15976") "NF-E1 DNA-binding protein (human)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hGATA1") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P15976") Annotation( ) "ERYF1") +AnnotationAssertion(Annotation( "UniProtKB:P15976") Annotation( ) "GATA1") +AnnotationAssertion(Annotation( "UniProtKB:P15976") Annotation( ) "GF1") +AnnotationAssertion( "PR:P15976") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "erythroid transcription factor (human)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (CD44 antigen (human)) + +AnnotationAssertion(Annotation( "PRO:WCB") Annotation( "UniProtKB:P16070") "A CD44 molecule that is encoded in the genome of human.") +AnnotationAssertion(Annotation( "UniProtKB:P16070") "PGP-I (human)") +AnnotationAssertion( "UniProtKB:P16070") +AnnotationAssertion(Annotation( "UniProtKB:P16070") "CDw44 (human)") +AnnotationAssertion(Annotation( "UniProtKB:P16070") "ECMR-III (human)") +AnnotationAssertion(Annotation( "UniProtKB:P16070") "GP90 lymphocyte homing/adhesion receptor (human)") +AnnotationAssertion(Annotation( "UniProtKB:P16070") "HUTCH-I (human)") +AnnotationAssertion(Annotation( "UniProtKB:P16070") "PGP-1 (human)") +AnnotationAssertion(Annotation( "UniProtKB:P16070") "epican (human)") +AnnotationAssertion(Annotation( "UniProtKB:P16070") "extracellular matrix receptor III (human)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hCD44") +AnnotationAssertion(Annotation( "UniProtKB:P16070") "heparan sulfate proteoglycan (human)") +AnnotationAssertion(Annotation( "UniProtKB:P16070") "hermes antigen (human)") +AnnotationAssertion(Annotation( "UniProtKB:P16070") "hyaluronate receptor (human)") +AnnotationAssertion(Annotation( "UniProtKB:P16070") "phagocytic glycoprotein 1 (human)") +AnnotationAssertion(Annotation( "UniProtKB:P16070") "phagocytic glycoprotein I (human)") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P16070") Annotation( ) "CD44") +AnnotationAssertion(Annotation( "UniProtKB:P16070") Annotation( ) "LHR") +AnnotationAssertion(Annotation( "UniProtKB:P16070") Annotation( ) "MDU2") +AnnotationAssertion(Annotation( "UniProtKB:P16070") Annotation( ) "MDU3") +AnnotationAssertion(Annotation( "UniProtKB:P16070") Annotation( ) "MIC4") +AnnotationAssertion( "PR:P16070") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "CD44 antigen (human)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (leukosialin (human)) + +AnnotationAssertion(Annotation( "PRO:WCB") Annotation( "UniProtKB:P16150") "A leukosialin that is encoded in the genome of human.") +AnnotationAssertion( "UniProtKB:P16150") +AnnotationAssertion(Annotation( "UniProtKB:P16150") "GALGP (human)") +AnnotationAssertion(Annotation( "UniProtKB:P16150") "GPL115 (human)") +AnnotationAssertion(Annotation( "UniProtKB:P16150") "galactoglycoprotein (human)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hSPN") +AnnotationAssertion(Annotation( "UniProtKB:P16150") "leukocyte sialoglycoprotein (human)") +AnnotationAssertion(Annotation( "UniProtKB:P16150") "sialophorin (human)") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P16150") Annotation( ) "CD43") +AnnotationAssertion(Annotation( "UniProtKB:P16150") Annotation( ) "SPN") +AnnotationAssertion( "PR:P16150") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "leukosialin (human)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (glutamyl aminopeptidase (mouse)) + +AnnotationAssertion(Annotation( "OMA:P16406") Annotation( "PRO:DNx") "A glutamyl aminopeptidase that is encoded in the genome of mouse.") +AnnotationAssertion(Annotation( "UniProtKB:P16406") "EAP (mouse)") +AnnotationAssertion( "UniProtKB:P16406") +AnnotationAssertion(Annotation( "UniProtKB:P16406") "AP-A (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P16406") "BP-1/6C3 antigen (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P16406") "CD249 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P16406") "aminopeptidase A (mouse)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mENPEP") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P16406") Annotation( ) "Enpep") +AnnotationAssertion( "PR:P16406") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "glutamyl aminopeptidase (mouse)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (interleukin-7 receptor subunit alpha (human)) + +AnnotationAssertion(Annotation( "PRO:WCB") Annotation( "UniProtKB:P16871") "An interleukin-7 receptor subunit alpha that is encoded in the genome of human.") +AnnotationAssertion( "UniProtKB:P16871") +AnnotationAssertion(Annotation( "UniProtKB:P16871") "CD127 (human)") +AnnotationAssertion(Annotation( "UniProtKB:P16871") "CDw127 (human)") +AnnotationAssertion(Annotation( "UniProtKB:P16871") "IL-7 receptor subunit alpha (human)") +AnnotationAssertion(Annotation( "UniProtKB:P16871") "IL-7R subunit alpha (human)") +AnnotationAssertion(Annotation( "UniProtKB:P16871") "IL-7R-alpha (human)") +AnnotationAssertion(Annotation( "UniProtKB:P16871") "IL-7RA (human)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hIL7R") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P16871") Annotation( ) "IL7R") +AnnotationAssertion( "PR:P16871") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "interleukin-7 receptor subunit alpha (human)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (interleukin-7 receptor subunit alpha (mouse)) + +AnnotationAssertion(Annotation( "OMA:P16872") Annotation( "PRO:DNx") "An interleukin-7 receptor subunit alpha that is encoded in the genome of mouse.") +AnnotationAssertion( "UniProtKB:P16872") +AnnotationAssertion(Annotation( "UniProtKB:P16872") "CD127 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P16872") "IL-7 receptor subunit alpha (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P16872") "IL-7R subunit alpha (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P16872") "IL-7R-alpha (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P16872") "IL-7RA (mouse)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mIL7R") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P16872") Annotation( ) "Il7r") +AnnotationAssertion( "PR:P16872") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "interleukin-7 receptor subunit alpha (mouse)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (transcription factor PU.1 (mouse)) + +AnnotationAssertion(Annotation( "OMA:P17433") Annotation( "PRO:DNx") "A transcription factor PU.1 that is encoded in the genome of mouse.") +AnnotationAssertion( "UniProtKB:P17433") +AnnotationAssertion(Annotation( "UniProtKB:P17433") "31 kDa-transforming protein (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P17433") "SFFV proviral integration 1 protein (mouse)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mSPI1") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P17433") Annotation( ) "Sfpi-1") +AnnotationAssertion(Annotation( "UniProtKB:P17433") Annotation( ) "Sfpi1") +AnnotationAssertion(Annotation( "UniProtKB:P17433") Annotation( ) "Spi1") +AnnotationAssertion( "PR:P17433") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "transcription factor PU.1 (mouse)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (T-cell acute lymphocytic leukemia protein 1 (human)) + +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( "UniProtKB:P17542") "A T-cell acute lymphocytic leukemia protein 1 that is encoded in the genome of human.") +AnnotationAssertion(Annotation(rdfs:label "PR:P17542 located_in GO:0005654") "Reactome:R-HSA-8956511") +AnnotationAssertion( "UniProtKB:P17542") +AnnotationAssertion(Annotation( "UniProtKB:P17542") "Stem cell protein (human)") +AnnotationAssertion(Annotation( "UniProtKB:P17542") "T-cell leukemia/lymphoma protein 5 (human)") +AnnotationAssertion(Annotation( "UniProtKB:P17542") "TAL-1 (human)") +AnnotationAssertion(Annotation( "UniProtKB:P17542") "class A basic helix-loop-helix protein 17 (human)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hTAL1") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P17542") Annotation( ) "BHLHA17") +AnnotationAssertion(Annotation( "UniProtKB:P17542") Annotation( ) "SCL") +AnnotationAssertion(Annotation( "UniProtKB:P17542") Annotation( ) "TAL1") +AnnotationAssertion(Annotation( "UniProtKB:P17542") Annotation( ) "TCL5") +AnnotationAssertion( "PR:P17542") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "T-cell acute lymphocytic leukemia protein 1 (human)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (erythroid transcription factor (chicken)) + +AnnotationAssertion(Annotation( "PANTHER:PTHR10071:SF26") Annotation( "PRO:DNx") "An erythroid transcription factor that is encoded in the genome of chicken.") +AnnotationAssertion( "UniProtKB:P17678") +AnnotationAssertion(Annotation( "UniProtKB:P17678") "Eryf1 (chicken)") +AnnotationAssertion(Annotation( "UniProtKB:P17678") "GATA-1 (chicken)") +AnnotationAssertion(Annotation( "UniProtKB:P17678") "GATA-binding factor 1 (chicken)") +AnnotationAssertion(Annotation( "UniProtKB:P17678") "NF-E1 DNA-binding protein (chicken)") +AnnotationAssertion(Annotation( "UniProtKB:P17678") "NF-E1a (chicken)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "chick-GATA1") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P17678") Annotation( ) "ERYF1") +AnnotationAssertion(Annotation( "UniProtKB:P17678") Annotation( ) "GATA1") +AnnotationAssertion( "PR:P17678") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "erythroid transcription factor (chicken)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (erythroid transcription factor (mouse)) + +AnnotationAssertion(Annotation( "OMA:P17679") Annotation( "PRO:DNx") "An erythroid transcription factor that is encoded in the genome of mouse.") +AnnotationAssertion( "UniProtKB:P17679") +AnnotationAssertion(Annotation( "UniProtKB:P17679") "Eryf1 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P17679") "GATA-1 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P17679") "GATA-binding factor 1 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P17679") "GF-1 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P17679") "NF-E1 DNA-binding protein (mouse)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mGATA1") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P17679") Annotation( ) "Gata1") +AnnotationAssertion(Annotation( "UniProtKB:P17679") Annotation( ) "Gf-1") +AnnotationAssertion( "PR:P17679") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "erythroid transcription factor (mouse)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (endoglin (human)) + +AnnotationAssertion(Annotation( "PRO:CNA") Annotation( "UniProtKB:P17813") "An endoglin that is encoded in the genome of human.") +AnnotationAssertion( "UniProtKB:P17813") +AnnotationAssertion(Annotation( "UniProtKB:P17813") "CD105 (human)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hENG") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P17813") Annotation( ) "END") +AnnotationAssertion(Annotation( "UniProtKB:P17813") Annotation( ) "ENG") +AnnotationAssertion( "PR:P17813") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "endoglin (human)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (transcription factor PU.1 (human)) + +AnnotationAssertion(Annotation( "PRO:WCB") Annotation( "UniProtKB:P17947") "A transcription factor PU.1 that is encoded in the genome of human.") +AnnotationAssertion(Annotation(rdfs:label "PR:P17947 located_in GO:0005654") "Reactome:R-HSA-8865503") +AnnotationAssertion( "UniProtKB:P17947") +AnnotationAssertion(Annotation( "UniProtKB:P17947") "31 kDa-transforming protein (human)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hSPI1") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P17947") Annotation( ) "SPI1") +AnnotationAssertion( "PR:P17947") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "transcription factor PU.1 (human)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (CD48 antigen (mouse)) + +AnnotationAssertion(Annotation( "OMA:P18181") Annotation( "PRO:DNx") "A CD48 molecule that is encoded in the genome of mouse.") +AnnotationAssertion( "UniProtKB:P18181") +AnnotationAssertion(Annotation( "UniProtKB:P18181") "BCM1 surface antigen (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P18181") "BLAST-1 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P18181") "CD48 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P18181") "HM48-1 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P18181") "MRC OX-45 surface antigen (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P18181") "SLAM family member 2 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P18181") "SLAMF2 (mouse)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mCD48") +AnnotationAssertion(Annotation( "UniProtKB:P18181") "sgp-60 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P18181") "signaling lymphocytic activation molecule 2 (mouse)") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P18181") Annotation( ) "Bcm-1") +AnnotationAssertion(Annotation( "UniProtKB:P18181") Annotation( ) "Cd48") +AnnotationAssertion( "PR:P18181") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "CD48 antigen (mouse)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (syndecan-1 (human)) + +AnnotationAssertion(Annotation( "PRO:WCB") Annotation( "UniProtKB:P18827") "A syndecan-1 that is encoded in the genome of human.") +AnnotationAssertion( "UniProtKB:P18827") +AnnotationAssertion(Annotation( "UniProtKB:P18827") "CD138 (human)") +AnnotationAssertion(Annotation( "UniProtKB:P18827") "SYND1 (human)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hSDC1") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P18827") Annotation( ) "SDC") +AnnotationAssertion(Annotation( "UniProtKB:P18827") Annotation( ) "SDC1") +AnnotationAssertion( "PR:P18827") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "syndecan-1 (human)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (syndecan-1 (mouse)) + +AnnotationAssertion(Annotation( "OMA:P18828") Annotation( "PRO:DNx") "A syndecan-1 that is encoded in the genome of mouse.") +AnnotationAssertion( "UniProtKB:P18828") +AnnotationAssertion(Annotation( "UniProtKB:P18828") "CD138 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P18828") "SYND1 (mouse)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mSDC1") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P18828") Annotation( ) "Sdc1") +AnnotationAssertion(Annotation( "UniProtKB:P18828") Annotation( ) "Synd-1") +AnnotationAssertion(Annotation( "UniProtKB:P18828") Annotation( ) "Synd1") +AnnotationAssertion( "PR:P18828") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "syndecan-1 (mouse)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (complement receptor type 2 (mouse)) + +AnnotationAssertion(Annotation( "PRO:WCB") "A complement receptor type 2 that is encoded in the genome of mouse.") +AnnotationAssertion( "UniProtKB:P19070") +AnnotationAssertion(Annotation( "UniProtKB:P19070") "CD21 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P19070") "complement C3d receptor (mouse)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mCR2") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P19070") Annotation( ) "Cr2") +AnnotationAssertion( "PR:P19070") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "complement receptor type 2 (mouse)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (B-lymphocyte antigen CD20 (mouse)) + +AnnotationAssertion(Annotation( "OMA:P19437") Annotation( "PRO:DNx") "A membrane-spanning 4-domains subfamily A member 1 that is encoded in the genome of mouse.") +AnnotationAssertion( "UniProtKB:P19437") +AnnotationAssertion(Annotation( "UniProtKB:P19437") "B-cell differentiation antigen Ly-44 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P19437") "CD20 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P19437") "lymphocyte antigen 44 (mouse)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mMS4A1") +AnnotationAssertion(Annotation( "UniProtKB:P19437") "membrane-spanning 4-domains subfamily A member 1 (mouse)") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P19437") Annotation( ) "Cd20") +AnnotationAssertion(Annotation( "UniProtKB:P19437") Annotation( ) "Ly-44") +AnnotationAssertion(Annotation( "UniProtKB:P19437") Annotation( ) "Ms4a1") +AnnotationAssertion(Annotation( "UniProtKB:P19437") Annotation( ) "Ms4a2") +AnnotationAssertion( "PR:P19437") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "B-lymphocyte antigen CD20 (mouse)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (complement receptor type 2 (human)) + +AnnotationAssertion(Annotation( "PRO:WCB") Annotation( "UniProtKB:P20023") "A complement receptor type 2 that is encoded in the genome of human.") +AnnotationAssertion( "UniProtKB:P20023") +AnnotationAssertion(Annotation( "UniProtKB:P20023") "CD21 (human)") +AnnotationAssertion(Annotation( "UniProtKB:P20023") "Cr2 (human)") +AnnotationAssertion(Annotation( "UniProtKB:P20023") "EBV receptor (human)") +AnnotationAssertion(Annotation( "UniProtKB:P20023") "complement C3d receptor (human)") +AnnotationAssertion(Annotation( "UniProtKB:P20023") "epstein-Barr virus receptor (human)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hCR2") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P20023") Annotation( ) "C3DR") +AnnotationAssertion(Annotation( "UniProtKB:P20023") Annotation( ) "CR2") +AnnotationAssertion( "PR:P20023") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "complement receptor type 2 (human)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (myeloid cell surface antigen CD33 (human)) + +AnnotationAssertion(Annotation( "PRO:WCB") Annotation( "UniProtKB:P20138") "A CD33 molecule that is encoded in the genome of human.") +AnnotationAssertion( "UniProtKB:P20138") +AnnotationAssertion(Annotation( "UniProtKB:P20138") "gp67 (human)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hCD33") +AnnotationAssertion(Annotation( "UniProtKB:P20138") "sialic acid-binding Ig-like lectin 3 (human)") +AnnotationAssertion(Annotation( "UniProtKB:P20138") "siglec-3 (human)") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P20138") Annotation( ) "CD33") +AnnotationAssertion(Annotation( "UniProtKB:P20138") Annotation( ) "SIGLEC3") +AnnotationAssertion( "PR:P20138") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "myeloid cell surface antigen CD33 (human)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (low affinity immunoglobulin epsilon Fc receptor (mouse)) + +AnnotationAssertion(Annotation( "OMA:P20693") Annotation( "PRO:DNx") "A low affinity immunoglobulin epsilon Fc receptor that is encoded in the genome of mouse.") +AnnotationAssertion( "UniProtKB:P20693") +AnnotationAssertion(Annotation( "UniProtKB:P20693") "CD23 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P20693") "Fc-epsilon-RII (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P20693") "lymphocyte IgE receptor (mouse)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mFCER2") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P20693") Annotation( ) "Fcer2") +AnnotationAssertion(Annotation( "UniProtKB:P20693") Annotation( ) "Fcer2a") +AnnotationAssertion( "PR:P20693") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "low affinity immunoglobulin epsilon Fc receptor (mouse)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (integrin alpha-X (human)) + +AnnotationAssertion( "An integrin alpha-X that is encoded in the genome of human.") +AnnotationAssertion( "UniProtKB:P20702") +AnnotationAssertion(Annotation( "UniProtKB:P20702") "CD11 antigen-like family member C (human)") +AnnotationAssertion(Annotation( "UniProtKB:P20702") "Leu M5 (human)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hITGAX") +AnnotationAssertion(Annotation( "UniProtKB:P20702") "leukocyte adhesion glycoprotein p150,95 alpha chain (human)") +AnnotationAssertion(Annotation( "UniProtKB:P20702") "leukocyte adhesion receptor p150,95 (human)") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P20702") Annotation( ) "CD11C") +AnnotationAssertion(Annotation( "UniProtKB:P20702") Annotation( ) "ITGAX") +AnnotationAssertion( "PR:P20702") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "integrin alpha-X (human)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (interleukin-5 receptor subunit alpha (mouse)) + +AnnotationAssertion(Annotation( "OMA:P21183") Annotation( "PRO:DNx") "An interleukin-5 receptor subunit alpha that is encoded in the genome of mouse.") +AnnotationAssertion( "UniProtKB:P21183") +AnnotationAssertion(Annotation( "UniProtKB:P21183") "CD125 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P21183") "IL-5 receptor subunit alpha (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P21183") "IL-5R subunit alpha (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P21183") "IL-5R-alpha (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P21183") "IL-5RA (mouse)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mIL5RA") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P21183") Annotation( ) "Il5r") +AnnotationAssertion(Annotation( "UniProtKB:P21183") Annotation( ) "Il5ra") +AnnotationAssertion( "PR:P21183") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "interleukin-5 receptor subunit alpha (mouse)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (V(D)J recombination-activating protein 2 (mouse)) + +AnnotationAssertion(Annotation( "OMA:P21784") Annotation( "PRO:DNx") "A V(D)J recombination-activating protein 2 that is encoded in the genome of mouse.") +AnnotationAssertion( "UniProtKB:P21784") +AnnotationAssertion(Annotation( "UniProtKB:P21784") "RAG-2 (mouse)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mRAG2") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P21784") Annotation( ) "Rag-2") +AnnotationAssertion(Annotation( "UniProtKB:P21784") Annotation( ) "Rag2") +AnnotationAssertion( "PR:P21784") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "V(D)J recombination-activating protein 2 (mouse)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (T-cell acute lymphocytic leukemia protein 1 homolog (mouse)) + +AnnotationAssertion(Annotation( "OMA:P22091") Annotation( "PRO:DNx") "A T-cell acute lymphocytic leukemia protein 1 that is encoded in the genome of mouse.") +AnnotationAssertion( "UniProtKB:P22091") +AnnotationAssertion(Annotation( "UniProtKB:P22091") "Stem cell protein (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P22091") "TAL-1 (mouse)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mTAL1") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P22091") Annotation( ) "Scl") +AnnotationAssertion(Annotation( "UniProtKB:P22091") Annotation( ) "Tal-1") +AnnotationAssertion(Annotation( "UniProtKB:P22091") Annotation( ) "Tal1") +AnnotationAssertion( "PR:P22091") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "T-cell acute lymphocytic leukemia protein 1 homolog (mouse)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (T-cell surface glycoprotein CD3 epsilon chain (mouse)) + +AnnotationAssertion(Annotation( "OMA:P22646") Annotation( "PRO:DNx") "A CD3 epsilon that is encoded in the genome of mouse.") +AnnotationAssertion( "UniProtKB:P22646") +AnnotationAssertion(Annotation( "UniProtKB:P22646") "CD3e (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P22646") "T-cell surface antigen T3/Leu-4 epsilon chain (mouse)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mCD3E") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P22646") Annotation( ) "Cd3e") +AnnotationAssertion( "PR:P22646") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "T-cell surface glycoprotein CD3 epsilon chain (mouse)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (endothelial transcription factor GATA-2 (human)) + +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( "UniProtKB:P23769") "An endothelial transcription factor GATA-2 that is encoded in the genome of human.") +AnnotationAssertion(Annotation(rdfs:label "PR:P23769 located_in GO:0005654") "Reactome:R-HSA-996735") +AnnotationAssertion( "UniProtKB:P23769") +AnnotationAssertion(Annotation( "UniProtKB:P23769") "GATA-binding protein 2 (human)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hGATA2") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P23769") Annotation( ) "GATA2") +AnnotationAssertion( "PR:P23769") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "endothelial transcription factor GATA-2 (human)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (GATA-binding factor 2 (chicken)) + +AnnotationAssertion(Annotation( "OMA:P23824") Annotation( "PANTHER:PTHR10071:SF107") Annotation( "PRO:DNx") "An endothelial transcription factor GATA-2 that is encoded in the genome of chicken.") +AnnotationAssertion( "UniProtKB:P23824") +AnnotationAssertion(Annotation( "UniProtKB:P23824") "GATA-2 (chicken)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "chick-GATA2") +AnnotationAssertion(Annotation( "UniProtKB:P23824") "transcription factor NF-E1b (chicken)") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P23824") Annotation( ) "GATA2") +AnnotationAssertion( "PR:P23824") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "GATA-binding factor 2 (chicken)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (V(D)J recombination-activating protein 1 (chicken)) + +AnnotationAssertion(Annotation( "OMA:P24271") Annotation( "PRO:DNx") "A V(D)J recombination-activating protein 1 that is encoded in the genome of chicken.") +AnnotationAssertion( "UniProtKB:P24271") +AnnotationAssertion(Annotation( "UniProtKB:P24271") "RAG-1 (chicken)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "chick-RAG1") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P24271") Annotation( ) "RAG1") +AnnotationAssertion( "PR:P24271") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "V(D)J recombination-activating protein 1 (chicken)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (signal transducer CD24 (mouse)) + +AnnotationAssertion(Annotation( "OMA:P24807") Annotation( "PRO:WCB") "A signal transducer CD24 that is encoded in the genome of mouse.") +AnnotationAssertion( "UniProtKB:P24807") +AnnotationAssertion(Annotation( "UniProtKB:P24807") "CD24 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P24807") "HSA (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P24807") "M1/69-J11D heat stable antigen (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P24807") "R13-Ag (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P24807") "X62 heat stable antigen (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P24807") "lymphocyte antigen 52 (mouse)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mCD24") +AnnotationAssertion(Annotation( "UniProtKB:P24807") "nectadrin (mouse)") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P24807") Annotation( ) "Cd24") +AnnotationAssertion(Annotation( "UniProtKB:P24807") Annotation( ) "Cd24a") +AnnotationAssertion(Annotation( "UniProtKB:P24807") Annotation( ) "Ly-52") +AnnotationAssertion( "PR:P24807") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "signal transducer CD24 (mouse)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (T-cell acute lymphocytic leukemia protein 1 homolog (chicken)) + +AnnotationAssertion(Annotation( "OMA:P24899") Annotation( "PRO:DNx") "A T-cell acute lymphocytic leukemia protein 1 that is encoded in the genome of chicken.") +AnnotationAssertion( "UniProtKB:P24899") +AnnotationAssertion(Annotation( "UniProtKB:P24899") "Stem cell protein (chicken)") +AnnotationAssertion(Annotation( "UniProtKB:P24899") "TAL-1 (chicken)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "chick-TAL1") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P24899") Annotation( ) "SCL") +AnnotationAssertion(Annotation( "UniProtKB:P24899") Annotation( ) "TAL1") +AnnotationAssertion( "PR:P24899") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "T-cell acute lymphocytic leukemia protein 1 homolog (chicken)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (signal transducer CD24 (human)) + +AnnotationAssertion(Annotation( "PRO:WCB") Annotation( "UniProtKB:P25063") "A signal transducer CD24 that is encoded in the genome of human.") +AnnotationAssertion( "UniProtKB:P25063") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hCD24") +AnnotationAssertion(Annotation( "UniProtKB:P25063") "small cell lung carcinoma cluster 4 antigen (human)") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P25063") Annotation( ) "CD24") +AnnotationAssertion(Annotation( "UniProtKB:P25063") Annotation( ) "CD24A") +AnnotationAssertion( "PR:P25063") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "signal transducer CD24 (human)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (B-lymphocyte antigen CD19 (mouse)) + +AnnotationAssertion(Annotation( "OMA:P25918") Annotation( "PRO:DNx") "A CD19 molecule that is encoded in the genome of mouse.") +AnnotationAssertion( "UniProtKB:P25918") +AnnotationAssertion(Annotation( "UniProtKB:P25918") "CD19 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P25918") "differentiation antigen CD19 (mouse)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mCD19") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P25918") Annotation( ) "Cd19") +AnnotationAssertion( "PR:P25918") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "B-lymphocyte antigen CD19 (mouse)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (CD27 antigen (human)) + +AnnotationAssertion(Annotation( "PRO:WCB") Annotation( "UniProtKB:P26842") "A CD27 molecule that is encoded in the genome of human.") +AnnotationAssertion( "UniProtKB:P26842") +AnnotationAssertion(Annotation( "UniProtKB:P26842") "CD27L receptor (human)") +AnnotationAssertion(Annotation( "UniProtKB:P26842") "T-cell activation antigen CD27 (human)") +AnnotationAssertion(Annotation( "UniProtKB:P26842") "T14 (human)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hCD27") +AnnotationAssertion(Annotation( "UniProtKB:P26842") "tumor necrosis factor receptor superfamily member 7 (human)") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P26842") Annotation( ) "CD27") +AnnotationAssertion(Annotation( "UniProtKB:P26842") Annotation( ) "TNFRSF7") +AnnotationAssertion( "PR:P26842") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "CD27 antigen (human)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (interleukin-3 receptor subunit alpha (human)) + +AnnotationAssertion(Annotation( "PRO:WCB") Annotation( "UniProtKB:P26951") "An interleukin-3 receptor class 2 alpha chain that is encoded in the genome of human.") +AnnotationAssertion( "UniProtKB:P26951") +AnnotationAssertion(Annotation( "UniProtKB:P26951") "CD123 (human)") +AnnotationAssertion(Annotation( "UniProtKB:P26951") "IL-3 receptor subunit alpha (human)") +AnnotationAssertion(Annotation( "UniProtKB:P26951") "IL-3R subunit alpha (human)") +AnnotationAssertion(Annotation( "UniProtKB:P26951") "IL-3R-alpha (human)") +AnnotationAssertion(Annotation( "UniProtKB:P26951") "IL-3RA (human)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hIL3RA") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P26951") Annotation( ) "IL3R") +AnnotationAssertion(Annotation( "UniProtKB:P26951") Annotation( ) "IL3RA") +AnnotationAssertion( "PR:P26951") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "interleukin-3 receptor subunit alpha (human)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (interleukin-3 receptor subunit alpha (mouse)) + +AnnotationAssertion(Annotation( "OMA:P26952") Annotation( "PRO:DNx") "An interleukin-3 receptor class 2 alpha chain that is encoded in the genome of mouse.") +AnnotationAssertion( "UniProtKB:P26952") +AnnotationAssertion(Annotation( "UniProtKB:P26952") "CD123 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P26952") "IL-3 receptor subunit alpha (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P26952") "IL-3R subunit alpha (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P26952") "IL-3R-alpha (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P26952") "IL-3RA (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P26952") "interleukin-3 receptor class II alpha chain (mouse)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mIL3RA") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P26952") Annotation( ) "Il3ra") +AnnotationAssertion(Annotation( "UniProtKB:P26952") Annotation( ) "Sut-1") +AnnotationAssertion( "PR:P26952") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "interleukin-3 receptor subunit alpha (mouse)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (killer cell lectin-like receptor subfamily B member 1C (mouse)) + +AnnotationAssertion(Annotation( "PRO:CNA") Annotation( "UniProtKB:P27814") "A killer cell lectin-like receptor subfamily B member 1C that is encoded in the genome of mouse.") +AnnotationAssertion( "UniProtKB:P27814") +AnnotationAssertion(Annotation( "UniProtKB:P27814") "CD161 antigen-like family member C (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P27814") "CD161c (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P27814") "Ly-55c (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P27814") "NK1.1 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P27814") "NKR-P1 40 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P27814") "NKR-P1.9 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P27814") "NKR-P1C (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P27814") "lymphocyte antigen 55c (mouse)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mKlrb1c") +AnnotationAssertion(Annotation( "UniProtKB:P27814") "natural killer cell surface protein P1-40 (mouse)") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P27814") Annotation( ) "Klrb1c") +AnnotationAssertion(Annotation( "UniProtKB:P27814") Annotation( ) "Ly55c") +AnnotationAssertion(Annotation( "UniProtKB:P27814") Annotation( ) "Nkrp1c") +AnnotationAssertion( "PR:P27814") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "killer cell lectin-like receptor subfamily B member 1C (mouse)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (hematopoietic progenitor cell antigen CD34 (human)) + +AnnotationAssertion( "A CD34 molecule that is encoded in the genome of human.") +AnnotationAssertion( "UniProtKB:P28906") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hCD34") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P28906") Annotation( ) "CD34") +AnnotationAssertion( "PR:P28906") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "hematopoietic progenitor cell antigen CD34 (human)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 (human)) + +AnnotationAssertion(Annotation( "PRO:WCB") Annotation( "UniProtKB:P28907") "An ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 that is encoded in the genome of human.") +AnnotationAssertion(Annotation(rdfs:label "PR:P28907 located_in GO:0005886") "Reactome:R-HSA-8938080") +AnnotationAssertion( "UniProtKB:P28907") +AnnotationAssertion(Annotation( "UniProtKB:P28907") "2'-phospho-ADP-ribosyl cyclase (human)") +AnnotationAssertion(Annotation( "UniProtKB:P28907") "2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase (human)") +AnnotationAssertion(Annotation( "UniProtKB:P28907") "2'-phospho-cyclic-ADP-ribose transferase (human)") +AnnotationAssertion( "ADP-ribosyl cyclase 1 (human)") +AnnotationAssertion(Annotation( "UniProtKB:P28907") "ADPRC 1 (human)") +AnnotationAssertion(Annotation( "UniProtKB:P28907") "T10 (human)") +AnnotationAssertion(Annotation( "UniProtKB:P28907") "cADPr hydrolase 1 (human)") +AnnotationAssertion(Annotation( "UniProtKB:P28907") "cyclic ADP-ribose hydrolase 1 (human)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hCD38") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P28907") Annotation( ) "CD38") +AnnotationAssertion( "PR:P28907") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 (human)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (low affinity immunoglobulin gamma Fc region receptor II-b (human)) + +AnnotationAssertion(Annotation( "PRO:CNA") Annotation( "UniProtKB:P31994") "A low affinity immunoglobulin gamma Fc region receptor II-b that is encoded in the genome of human.") +AnnotationAssertion(Annotation( "UniProtKB:P31994") "CD32 (human)") +AnnotationAssertion(Annotation( "UniProtKB:P31994") "CDw32 (human)") +AnnotationAssertion( "UniProtKB:P31994") +AnnotationAssertion(Annotation( "UniProtKB:P31994") "Fc-gamma RII-b (human)") +AnnotationAssertion(Annotation( "UniProtKB:P31994") "Fc-gamma-RIIb (human)") +AnnotationAssertion(Annotation( "UniProtKB:P31994") "FcRII-b (human)") +AnnotationAssertion(Annotation( "UniProtKB:P31994") "IgG Fc receptor II-b (human)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hFCGR2B") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P31994") Annotation( ) "CD32") +AnnotationAssertion(Annotation( "UniProtKB:P31994") Annotation( ) "FCG2") +AnnotationAssertion(Annotation( "UniProtKB:P31994") Annotation( ) "FCGR2B") +AnnotationAssertion(Annotation( "UniProtKB:P31994") Annotation( ) "IGFR2") +AnnotationAssertion( "PR:P31994") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "low affinity immunoglobulin gamma Fc region receptor II-b (human)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (carcinoembryonic antigen-related cell adhesion molecule 8 (human)) + +AnnotationAssertion(Annotation( "PRO:CNA") Annotation( "UniProtKB:P31997") "A carcinoembryonic antigen-related cell adhesion molecule 8 that is encoded in the genome of human.") +AnnotationAssertion( "UniProtKB:P31997") +AnnotationAssertion(Annotation( "UniProtKB:P31997") "CD66b (human)") +AnnotationAssertion(Annotation( "UniProtKB:P31997") "CD67 antigen (human)") +AnnotationAssertion(Annotation( "UniProtKB:P31997") "carcinoembryonic antigen CGM6 (human)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hCEACAM8") +AnnotationAssertion(Annotation( "UniProtKB:P31997") "non-specific cross-reacting antigen NCA-95 (human)") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P31997") Annotation( ) "CEACAM8") +AnnotationAssertion(Annotation( "UniProtKB:P31997") Annotation( ) "CGM6") +AnnotationAssertion( "PR:P31997") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "carcinoembryonic antigen-related cell adhesion molecule 8 (human)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cadherin-5 (human)) + +AnnotationAssertion(Annotation( "PRO:WCB") Annotation( "UniProtKB:P33151") "A cadherin-5 that is encoded in the genome of human.") +AnnotationAssertion( "UniProtKB:P33151") +AnnotationAssertion(Annotation( "UniProtKB:P33151") "7B4 antigen (human)") +AnnotationAssertion(Annotation( "UniProtKB:P33151") "CD144 (human)") +AnnotationAssertion(Annotation( "UniProtKB:P33151") "VE-cadherin (human)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hCDH5") +AnnotationAssertion(Annotation( "UniProtKB:P33151") "vascular endothelial cadherin (human)") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P33151") Annotation( ) "CDH5") +AnnotationAssertion( "PR:P33151") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "cadherin-5 (human)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (urokinase plasminogen activator surface receptor (mouse)) + +AnnotationAssertion(Annotation( "OMA:P35456") Annotation( "PRO:DNx") "A urokinase plasminogen activator surface receptor that is encoded in the genome of mouse.") +AnnotationAssertion( "UniProtKB:P35456") +AnnotationAssertion(Annotation( "UniProtKB:P35456") "CD87 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P35456") "U-PAR (mouse)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mPLAUR") +AnnotationAssertion(Annotation( "UniProtKB:P35456") "uPAR (mouse)") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P35456") Annotation( ) "Plaur") +AnnotationAssertion( "PR:P35456") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "urokinase plasminogen activator surface receptor (mouse)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (lymphocyte antigen 6G (mouse)) + +AnnotationAssertion(Annotation( "PRO:CNA") Annotation( "UniProtKB:P35461") "A lymphocyte antigen 6G that is encoded in the genome of mouse.") +AnnotationAssertion( "UniProtKB:P35461") +AnnotationAssertion(Annotation( "UniProtKB:P35461") "Ly-6G (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P35461") "Ly-6G.1 (mouse)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mLy6g") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P35461") Annotation( ) "Ly6g") +AnnotationAssertion( "PR:P35461") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "lymphocyte antigen 6G (mouse)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (vascular endothelial growth factor receptor 2 (mouse)) + +AnnotationAssertion(Annotation( "OMA:P35918") Annotation( "PRO:DNx") "A vascular endothelial growth factor receptor 2 that is encoded in the genome of mouse.") +AnnotationAssertion( "UniProtKB:P35918") +AnnotationAssertion(Annotation( "UniProtKB:P35918") "CD309 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P35918") "FLK-1 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P35918") "VEGFR-2 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P35918") "fetal liver kinase 1 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P35918") "kinase NYK (mouse)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mKDR") +AnnotationAssertion(Annotation( "UniProtKB:P35918") "protein-tyrosine kinase receptor flk-1 (mouse)") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P35918") Annotation( ) "Flk-1") +AnnotationAssertion(Annotation( "UniProtKB:P35918") Annotation( ) "Flk1") +AnnotationAssertion(Annotation( "UniProtKB:P35918") Annotation( ) "Kdr") +AnnotationAssertion( "PR:P35918") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "vascular endothelial growth factor receptor 2 (mouse)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (vascular endothelial growth factor receptor 2 (human)) + +AnnotationAssertion(Annotation( "PRO:WCB") Annotation( "UniProtKB:P35968") "A vascular endothelial growth factor receptor 2 that is encoded in the genome of human.") +AnnotationAssertion( "DTO:03100560") +AnnotationAssertion( "UniProtKB:P35968") +AnnotationAssertion(Annotation( "UniProtKB:P35968") "CD309 (human)") +AnnotationAssertion(Annotation( "UniProtKB:P35968") "FLK-1 (human)") +AnnotationAssertion(Annotation( "UniProtKB:P35968") "VEGFR-2 (human)") +AnnotationAssertion(Annotation( "UniProtKB:P35968") "fetal liver kinase 1 (human)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hKDR") +AnnotationAssertion(Annotation( "UniProtKB:P35968") "kinase insert domain receptor (human)") +AnnotationAssertion(Annotation( "UniProtKB:P35968") "protein-tyrosine kinase receptor flk-1 (human)") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P35968") Annotation( ) "FLK1") +AnnotationAssertion(Annotation( "UniProtKB:P35968") Annotation( ) "KDR") +AnnotationAssertion(Annotation( "UniProtKB:P35968") Annotation( ) "VEGFR2") +AnnotationAssertion( "PR:P35968") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "vascular endothelial growth factor receptor 2 (human)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (DNA nucleotidylexotransferase (chicken)) + +AnnotationAssertion(Annotation( "PRO:DNx") "A DNA nucleotidylexotransferase that is encoded in the genome of chicken.") +AnnotationAssertion( "UniProtKB:P36195") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "chick-DNTT") +AnnotationAssertion(Annotation( "UniProtKB:P36195") "terminal addition enzyme (chicken)") +AnnotationAssertion(Annotation( "UniProtKB:P36195") "terminal deoxynucleotidyltransferase (chicken)") +AnnotationAssertion(Annotation( "UniProtKB:P36195") "terminal transferase (chicken)") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P36195") Annotation( ) "DNTT") +AnnotationAssertion(Annotation( "UniProtKB:P36195") Annotation( ) "TDT") +AnnotationAssertion( "PR:P36195") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "DNA nucleotidylexotransferase (chicken)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (receptor-type tyrosine-protein kinase FLT3 (human)) + +AnnotationAssertion(Annotation( "PRO:WCB") Annotation( "UniProtKB:P36888") "A receptor-type tyrosine-protein kinase FLT3 that is encoded in the genome of human.") +AnnotationAssertion(Annotation( "UniProtKB:P36888") "STK-1 (human)") +AnnotationAssertion( "DTO:03100154") +AnnotationAssertion( "UniProtKB:P36888") +AnnotationAssertion(Annotation( "UniProtKB:P36888") "FL cytokine receptor (human)") +AnnotationAssertion(Annotation( "UniProtKB:P36888") "FLK-2 (human)") +AnnotationAssertion(Annotation( "UniProtKB:P36888") "FLT-3 (human)") +AnnotationAssertion(Annotation( "UniProtKB:P36888") "Stem cell tyrosine kinase 1 (human)") +AnnotationAssertion(Annotation( "UniProtKB:P36888") "fetal liver kinase-2 (human)") +AnnotationAssertion(Annotation( "UniProtKB:P36888") "fms-like tyrosine kinase 3 (human)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hFLT3") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P36888") Annotation( ) "CD135") +AnnotationAssertion(Annotation( "UniProtKB:P36888") Annotation( ) "FLK2") +AnnotationAssertion(Annotation( "UniProtKB:P36888") Annotation( ) "FLT3") +AnnotationAssertion(Annotation( "UniProtKB:P36888") Annotation( ) "STK1") +AnnotationAssertion( "PR:P36888") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "receptor-type tyrosine-protein kinase FLT3 (human)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (fibroblast growth factor 8 (mouse)) + +AnnotationAssertion(Annotation( "OMA:P37237") Annotation( "PRO:DNx") "A fibroblast growth factor 8 that is encoded in the genome of mouse.") +AnnotationAssertion( "UniProtKB:P37237") +AnnotationAssertion(Annotation( "UniProtKB:P37237") "AIGF (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P37237") "FGF-8 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P37237") "androgen-induced growth factor (mouse)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mFGF8") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P37237") Annotation( ) "Aigf") +AnnotationAssertion(Annotation( "UniProtKB:P37237") Annotation( ) "Fgf8") +AnnotationAssertion(Annotation( "UniProtKB:P37237") "HBGF-8 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P37237") "heparin-binding growth factor 8 (mouse)") +AnnotationAssertion( "PR:P37237") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "fibroblast growth factor 8 (mouse)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (CD27 antigen (mouse)) + +AnnotationAssertion(Annotation( "OMA:P41272") Annotation( "PRO:DNx") "A CD27 molecule that is encoded in the genome of mouse.") +AnnotationAssertion( "UniProtKB:P41272") +AnnotationAssertion(Annotation( "UniProtKB:P41272") "CD27 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P41272") "CD27L receptor (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P41272") "T-cell activation antigen CD27 (mouse)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mCD27") +AnnotationAssertion(Annotation( "UniProtKB:P41272") "tumor necrosis factor receptor superfamily member 7 (mouse)") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P41272") Annotation( ) "Cd27") +AnnotationAssertion(Annotation( "UniProtKB:P41272") Annotation( ) "Tnfrsf7") +AnnotationAssertion( "PR:P41272") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "CD27 antigen (mouse)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (C-C chemokine receptor type 2 (human)) + +AnnotationAssertion(Annotation( "PRO:WCB") Annotation( "UniProtKB:P41597") "A C-C chemokine receptor type 2 that is encoded in the genome of human.") +AnnotationAssertion( "DTO:02100054") +AnnotationAssertion(Annotation(rdfs:label "PR:P41597 located_in GO:0005886") "Reactome:R-HSA-2976755") +AnnotationAssertion( "UniProtKB:P41597") +AnnotationAssertion(Annotation( "UniProtKB:P41597") "C-C CKR-2 (human)") +AnnotationAssertion(Annotation( "UniProtKB:P41597") "CC-CKR-2 (human)") +AnnotationAssertion(Annotation( "UniProtKB:P41597") "CCR-2 (human)") +AnnotationAssertion(Annotation( "UniProtKB:P41597") "CD192 (human)") +AnnotationAssertion(Annotation( "UniProtKB:P41597") "MCP-1-R (human)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hCCR2") +AnnotationAssertion(Annotation( "UniProtKB:P41597") "monocyte chemoattractant protein 1 receptor (human)") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P41597") Annotation( ) "CCR2") +AnnotationAssertion(Annotation( "UniProtKB:P41597") Annotation( ) "CMKBR2") +AnnotationAssertion( "PR:P41597") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "C-C chemokine receptor type 2 (human)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cathepsin K (human)) + +AnnotationAssertion(Annotation( "PRO:WCB") Annotation( "UniProtKB:P43235") "A cathepsin K that is encoded in the genome of human.") +AnnotationAssertion(Annotation( "UniProtKB:P43235") "cathepsin X (human)") +AnnotationAssertion( "UniProtKB:P43235") +AnnotationAssertion(Annotation( "UniProtKB:P43235") "cathepsin O2 (human)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hCTSK") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P43235") Annotation( ) "CTSK") +AnnotationAssertion(Annotation( "UniProtKB:P43235") Annotation( ) "CTSO") +AnnotationAssertion(Annotation( "UniProtKB:P43235") Annotation( ) "CTSO2") +AnnotationAssertion(Annotation( "UniProtKB:P43235") "cathepsin O (human)") +AnnotationAssertion( "PR:P43235") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "cathepsin K (human)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (CX3C chemokine receptor 1 (human)) + +AnnotationAssertion(Annotation( "PRO:WCB") Annotation( "UniProtKB:P49238") "A CX3C chemokine receptor 1 that is encoded in the genome of human.") +AnnotationAssertion( "DTO:02100074") +AnnotationAssertion(Annotation(rdfs:label "PR:P49238 located_in GO:0005886") "Reactome:R-HSA-2980688") +AnnotationAssertion( "UniProtKB:P49238") +AnnotationAssertion(Annotation( "UniProtKB:P49238") "C-X3-C CKR-1 (human)") +AnnotationAssertion(Annotation( "UniProtKB:P49238") "CMK-BRL-1 (human)") +AnnotationAssertion(Annotation( "UniProtKB:P49238") "CMK-BRL1 (human)") +AnnotationAssertion(Annotation( "UniProtKB:P49238") "G-protein coupled receptor 13 (human)") +AnnotationAssertion(Annotation( "UniProtKB:P49238") "V28 (human)") +AnnotationAssertion(Annotation( "UniProtKB:P49238") "beta chemokine receptor-like 1 (human)") +AnnotationAssertion(Annotation( "UniProtKB:P49238") "fractalkine receptor (human)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hCX3CR1") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P49238") Annotation( ) "CMKBRL1") +AnnotationAssertion(Annotation( "UniProtKB:P49238") Annotation( ) "CX3CR1") +AnnotationAssertion(Annotation( "UniProtKB:P49238") Annotation( ) "GPR13") +AnnotationAssertion( "PR:P49238") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "CX3C chemokine receptor 1 (human)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (CCAAT/enhancer-binding protein alpha (human)) + +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( "UniProtKB:P49715") "A CCAAT/enhancer-binding protein alpha that is encoded in the genome of human.") +AnnotationAssertion(Annotation(rdfs:label "PR:P49715 located_in GO:0005654") "Reactome:R-HSA-381289") +AnnotationAssertion( "UniProtKB:P49715") +AnnotationAssertion(Annotation( "UniProtKB:P49715") "C/EBP alpha (human)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hCEBPA") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P49715") Annotation( ) "CEBP") +AnnotationAssertion(Annotation( "UniProtKB:P49715") Annotation( ) "CEBPA") +AnnotationAssertion( "PR:P49715") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "CCAAT/enhancer-binding protein alpha (human)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (T-cell antigen CD7 (mouse)) + +AnnotationAssertion(Annotation( "OMA:P50283") Annotation( "PRO:DNx") "A CD7 molecule that is encoded in the genome of mouse.") +AnnotationAssertion( "UniProtKB:P50283") +AnnotationAssertion(Annotation( "UniProtKB:P50283") "CD7 (mouse)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mCD7") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P50283") Annotation( ) "Cd7") +AnnotationAssertion( "PR:P50283") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "T-cell antigen CD7 (mouse)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (C-C chemokine receptor type 2 (mouse)) + +AnnotationAssertion(Annotation( "OMA:P51683") Annotation( "PRO:DNx") "A C-C chemokine receptor type 2 that is encoded in the genome of mouse.") +AnnotationAssertion( "UniProtKB:P51683") +AnnotationAssertion(Annotation( "UniProtKB:P51683") "C-C CKR-2 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P51683") "CC-CKR-2 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P51683") "CCR-2 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P51683") "CCR2 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P51683") "CD192 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P51683") "JE/FIC receptor (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P51683") "MCP-1 receptor (mouse)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mCCR2") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P51683") Annotation( ) "Ccr2") +AnnotationAssertion(Annotation( "UniProtKB:P51683") Annotation( ) "Cmkbr2") +AnnotationAssertion( "PR:P51683") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "C-C chemokine receptor type 2 (mouse)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (CCAAT/enhancer-binding protein alpha (mouse)) + +AnnotationAssertion(Annotation( "OMA:P53566") Annotation( "PRO:DNx") "A CCAAT/enhancer-binding protein alpha that is encoded in the genome of mouse.") +AnnotationAssertion( "UniProtKB:P53566") +AnnotationAssertion(Annotation( "UniProtKB:P53566") "C/EBP alpha (mouse)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mCEBPA") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P53566") Annotation( ) "Cebp") +AnnotationAssertion(Annotation( "UniProtKB:P53566") Annotation( ) "Cebpa") +AnnotationAssertion( "PR:P53566") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "CCAAT/enhancer-binding protein alpha (mouse)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (fibroblast growth factor 8 (human)) + +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( "UniProtKB:P55075") "A fibroblast growth factor 8 that is encoded in the genome of human.") +AnnotationAssertion(Annotation( "UniProtKB:P55075") "HBGF-8 (human)") +AnnotationAssertion(Annotation( "UniProtKB:P55075") "heparin-binding growth factor 8 (human)") +AnnotationAssertion( "UniProtKB:P55075") +AnnotationAssertion(Annotation( "UniProtKB:P55075") "FGF-8 (human)") +AnnotationAssertion(Annotation( "UniProtKB:P55075") "androgen-induced growth factor (human)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hFGF8") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P55075") Annotation( ) "AIGF") +AnnotationAssertion(Annotation( "UniProtKB:P55075") Annotation( ) "FGF8") +AnnotationAssertion( "PR:P55075") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "fibroblast growth factor 8 (human)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cathepsin K (mouse)) + +AnnotationAssertion(Annotation( "OMA:P55097") Annotation( "PRO:DNx") "A cathepsin K that is encoded in the genome of mouse.") +AnnotationAssertion( "UniProtKB:P55097") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mCTSK") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P55097") Annotation( ) "Ctsk") +AnnotationAssertion( "PR:P55097") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "cathepsin K (mouse)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cadherin-5 (mouse)) + +AnnotationAssertion(Annotation( "OMA:P55284") Annotation( "PRO:DNx") "A cadherin-5 that is encoded in the genome of mouse.") +AnnotationAssertion( "UniProtKB:P55284") +AnnotationAssertion(Annotation( "UniProtKB:P55284") "CD144 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P55284") "VE-cadherin (mouse)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mCDH5") +AnnotationAssertion(Annotation( "UniProtKB:P55284") "vascular endothelial cadherin (mouse)") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P55284") Annotation( ) "Cdh5") +AnnotationAssertion( "PR:P55284") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "cadherin-5 (mouse)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (V(D)J recombination-activating protein 2 (human)) + +AnnotationAssertion(Annotation( "PRO:CNA") Annotation( "UniProtKB:P55895") "A V(D)J recombination-activating protein 2 that is encoded in the genome of human.") +AnnotationAssertion(Annotation(rdfs:label "PR:P55895 located_in GO:0005654") "Reactome:R-HSA-5692675") +AnnotationAssertion( "UniProtKB:P55895") +AnnotationAssertion(Annotation( "UniProtKB:P55895") "RAG-2 (human)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hRAG2") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P55895") Annotation( ) "RAG2") +AnnotationAssertion( "PR:P55895") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "V(D)J recombination-activating protein 2 (human)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 (mouse)) + +AnnotationAssertion(Annotation( "OMA:P56528") Annotation( "PRO:DNx") "An ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 that is encoded in the genome of mouse.") +AnnotationAssertion( "UniProtKB:P56528") +AnnotationAssertion(Annotation( "UniProtKB:P56528") "2'-phospho-ADP-ribosyl cyclase (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P56528") "2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P56528") "2'-phospho-cyclic-ADP-ribose transferase (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P56528") "ADP-ribosyl cyclase 1 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P56528") "ADPRC 1 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P56528") "CD38 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P56528") "I-19 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P56528") "NIM-R5 antigen (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P56528") "cADPr hydrolase 1 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:P56528") "cyclic ADP-ribose hydrolase 1 (mouse)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mCD38") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P56528") Annotation( ) "Cd38") +AnnotationAssertion( "PR:P56528") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 (mouse)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (insulin (chicken)) + +AnnotationAssertion(Annotation( "OMA:P67970") Annotation( "PRO:DNx") "An insulin gene translation product that is encoded in the genome of chicken.") +AnnotationAssertion( "UniProtKB:P67970") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "chick-INS") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P67970") Annotation( ) "INS") +AnnotationAssertion( "PR:P67970") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "insulin (chicken)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (nuclear factor NF-kappa-B p100 subunit (chicken)) + +AnnotationAssertion(Annotation( "PRO:DNx") "A nuclear factor NF-kappa-B p100 subunit that is encoded in the genome of chicken.") +AnnotationAssertion( "UniProtKB:P98150") +AnnotationAssertion(Annotation( "UniProtKB:P98150") "DNA-binding factor KBF2 (chicken)") +AnnotationAssertion(Annotation( "UniProtKB:P98150") "Lyt-10 (chicken)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "chick-NFKB2") +AnnotationAssertion(Annotation( "UniProtKB:P98150") "nuclear factor NF-kappa-B p97 subunit (chicken)") +AnnotationAssertion(Annotation( "UniProtKB:P98150") "nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (chicken)") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:P98150") Annotation( ) "NFKB2") +AnnotationAssertion( "PR:P98150") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "nuclear factor NF-kappa-B p100 subunit (chicken)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (receptor-type tyrosine-protein kinase FLT3 (mouse)) + +AnnotationAssertion(Annotation( "OMA:Q00342") Annotation( "PRO:DNx") "A receptor-type tyrosine-protein kinase FLT3 that is encoded in the genome of mouse.") +AnnotationAssertion( "UniProtKB:Q00342") +AnnotationAssertion(Annotation( "UniProtKB:Q00342") "CD135 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:Q00342") "FL cytokine receptor (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:Q00342") "FLK-2 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:Q00342") "FLT-3 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:Q00342") "fetal liver kinase 2 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:Q00342") "fms-like tyrosine kinase 3 (mouse)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mFLT3") +AnnotationAssertion(Annotation( "UniProtKB:Q00342") "tyrosine-protein kinase receptor flk-2 (mouse)") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:Q00342") Annotation( ) "Flk-2") +AnnotationAssertion(Annotation( "UniProtKB:Q00342") Annotation( ) "Flt-3") +AnnotationAssertion(Annotation( "UniProtKB:Q00342") Annotation( ) "Flt3") +AnnotationAssertion( "PR:Q00342") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "receptor-type tyrosine-protein kinase FLT3 (mouse)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (nuclear factor NF-kappa-B p100 subunit (human)) + +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( "UniProtKB:Q00653") "A nuclear factor NF-kappa-B p100 subunit that is encoded in the genome of human.") +AnnotationAssertion(Annotation(rdfs:label "PR:Q00653 located_in GO:0005829") "Reactome:R-HSA-2677931") +AnnotationAssertion( "UniProtKB:Q00653") +AnnotationAssertion(Annotation( "UniProtKB:Q00653") "DNA-binding factor KBF2 (human)") +AnnotationAssertion(Annotation( "UniProtKB:Q00653") "H2TF1 (human)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hNFKB2") +AnnotationAssertion(Annotation( "UniProtKB:Q00653") "lymphocyte translocation chromosome 10 protein (human)") +AnnotationAssertion(Annotation( "UniProtKB:Q00653") "nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (human)") +AnnotationAssertion(Annotation( "UniProtKB:Q00653") "oncogene Lyt-10 (human)") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:Q00653") Annotation( ) "LYT10") +AnnotationAssertion(Annotation( "UniProtKB:Q00653") Annotation( ) "NFKB2") +AnnotationAssertion( "PR:Q00653") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "nuclear factor NF-kappa-B p100 subunit (human)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (interleukin-5 receptor subunit alpha (human)) + +AnnotationAssertion(Annotation( "PRO:WCB") Annotation( "UniProtKB:Q01344") "An interleukin-5 receptor subunit alpha that is encoded in the genome of human.") +AnnotationAssertion( "UniProtKB:Q01344") +AnnotationAssertion(Annotation( "UniProtKB:Q01344") "CD125 (human)") +AnnotationAssertion(Annotation( "UniProtKB:Q01344") "CDw125 (human)") +AnnotationAssertion(Annotation( "UniProtKB:Q01344") "IL-5 receptor subunit alpha (human)") +AnnotationAssertion(Annotation( "UniProtKB:Q01344") "IL-5R subunit alpha (human)") +AnnotationAssertion(Annotation( "UniProtKB:Q01344") "IL-5R-alpha (human)") +AnnotationAssertion(Annotation( "UniProtKB:Q01344") "IL-5RA (human)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hIL5RA") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:Q01344") Annotation( ) "IL5R") +AnnotationAssertion(Annotation( "UniProtKB:Q01344") Annotation( ) "IL5RA") +AnnotationAssertion( "PR:Q01344") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "interleukin-5 receptor subunit alpha (human)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (paired box protein Pax-5 (human)) + +AnnotationAssertion(Annotation( "PRO:WCB") Annotation( "UniProtKB:Q02548") "A paired box protein PAX-5 that is encoded in the genome of human.") +AnnotationAssertion(Annotation(rdfs:label "PR:Q02548 located_in GO:0005654") "Reactome:R-HSA-158583") +AnnotationAssertion( "UniProtKB:Q02548") +AnnotationAssertion(Annotation( "UniProtKB:Q02548") "B-cell-specific transcription factor (human)") +AnnotationAssertion(Annotation( "UniProtKB:Q02548") "BSAP (human)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hPAX5") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:Q02548") Annotation( ) "PAX5") +AnnotationAssertion( "PR:Q02548") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "paired box protein Pax-5 (human)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (paired box protein Pax-5 (mouse)) + +AnnotationAssertion(Annotation( "OMA:Q02650") Annotation( "PRO:DNx") "A paired box protein PAX-5 that is encoded in the genome of mouse.") +AnnotationAssertion( "UniProtKB:Q02650") +AnnotationAssertion(Annotation( "UniProtKB:Q02650") "B-cell-specific transcription factor (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:Q02650") "BSAP (mouse)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mPAX5") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:Q02650") Annotation( ) "Pax-5") +AnnotationAssertion(Annotation( "UniProtKB:Q02650") Annotation( ) "Pax5") +AnnotationAssertion( "PR:Q02650") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "paired box protein Pax-5 (mouse)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (urokinase plasminogen activator surface receptor (human)) + +AnnotationAssertion(Annotation( "PRO:WCB") Annotation( "UniProtKB:Q03405") "A urokinase plasminogen activator surface receptor that is encoded in the genome of human.") +AnnotationAssertion( "UniProtKB:Q03405") +AnnotationAssertion(Annotation( "UniProtKB:Q03405") "CD87 (human)") +AnnotationAssertion(Annotation( "UniProtKB:Q03405") "U-PAR (human)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hPLAUR") +AnnotationAssertion(Annotation( "UniProtKB:Q03405") "monocyte activation antigen Mo3 (human)") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:Q03405") Annotation( ) "MO3") +AnnotationAssertion(Annotation( "UniProtKB:Q03405") Annotation( ) "PLAUR") +AnnotationAssertion(Annotation( "UniProtKB:Q03405") Annotation( ) "UPAR") +AnnotationAssertion( "PR:Q03405") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "urokinase plasminogen activator surface receptor (human)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (tartrate-resistant acid phosphatase type 5 (mouse)) + +AnnotationAssertion(Annotation( "OMA:Q05117") Annotation( "PRO:DNx") "A tartrate-resistant acid phosphatase type 5 that is encoded in the genome of mouse.") +AnnotationAssertion( "UniProtKB:Q05117") +AnnotationAssertion(Annotation( "UniProtKB:Q05117") "TR-AP (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:Q05117") "TrATPase (mouse)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mACP5") +AnnotationAssertion(Annotation( "UniProtKB:Q05117") "tartrate-resistant acid ATPase (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:Q05117") "type 5 acid phosphatase (mouse)") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:Q05117") Annotation( ) "Acp5") +AnnotationAssertion(Annotation( "UniProtKB:Q05117") Annotation( ) "T5ap") +AnnotationAssertion(Annotation( "UniProtKB:Q05117") Annotation( ) "Trap") +AnnotationAssertion( "PR:Q05117") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "tartrate-resistant acid phosphatase type 5 (mouse)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (glutamyl aminopeptidase (human)) + +AnnotationAssertion(Annotation( "PRO:WCB") Annotation( "UniProtKB:Q07075") "A glutamyl aminopeptidase that is encoded in the genome of human.") +AnnotationAssertion(Annotation( "UniProtKB:Q07075") "EAP (human)") +AnnotationAssertion(Annotation(rdfs:label "PR:Q07075 located_in GO:0005886") "Reactome:R-HSA-2022341") +AnnotationAssertion( "UniProtKB:Q07075") +AnnotationAssertion(Annotation( "UniProtKB:Q07075") "AP-A (human)") +AnnotationAssertion(Annotation( "UniProtKB:Q07075") "CD249 (human)") +AnnotationAssertion(Annotation( "UniProtKB:Q07075") "aminopeptidase A (human)") +AnnotationAssertion(Annotation( "UniProtKB:Q07075") "differentiation antigen gp160 (human)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hENPEP") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:Q07075") Annotation( ) "ENPEP") +AnnotationAssertion( "PR:Q07075") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "glutamyl aminopeptidase (human)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (natural killer cell receptor 2B4 (mouse)) + +AnnotationAssertion(Annotation( "OMA:Q07763") Annotation( "PRO:DNx") "A natural killer cell receptor 2B4 that is encoded in the genome of mouse.") +AnnotationAssertion( "UniProtKB:Q07763") +AnnotationAssertion(Annotation( "UniProtKB:Q07763") "CD244 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:Q07763") "NK cell type I receptor protein 2B4 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:Q07763") "NKR2B4 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:Q07763") "SLAM family member 4 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:Q07763") "SLAMF4 (mouse)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mCD244") +AnnotationAssertion(Annotation( "UniProtKB:Q07763") "non-MHC restricted killing associated (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:Q07763") "signaling lymphocytic activation molecule 4 (mouse)") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:Q07763") Annotation( ) "2b4") +AnnotationAssertion(Annotation( "UniProtKB:Q07763") Annotation( ) "Cd244") +AnnotationAssertion(Annotation( "UniProtKB:Q07763") Annotation( ) "Nmrk") +AnnotationAssertion( "PR:Q07763") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "natural killer cell receptor 2B4 (mouse)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (mast/stem cell growth factor receptor Kit (chicken)) + +AnnotationAssertion(Annotation( "OMA:Q08156") Annotation( "PANTHER:PTHR24416:SF238") Annotation( "PRO:DNx") "A mast/stem cell growth factor receptor that is encoded in the genome of chicken.") +AnnotationAssertion( "UniProtKB:Q08156") +AnnotationAssertion(Annotation( "UniProtKB:Q08156") "SCFR (chicken)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "chick-KIT") +AnnotationAssertion(Annotation( "UniProtKB:Q08156") "proto-oncogene c-Kit (chicken)") +AnnotationAssertion(Annotation( "UniProtKB:Q08156") "tyrosine-protein kinase Kit (chicken)") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:Q08156") Annotation( ) "KIT") +AnnotationAssertion( "PR:Q08156") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "mast/stem cell growth factor receptor Kit (chicken)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (signaling lymphocytic activation molecule (human)) + +AnnotationAssertion(Annotation( "PRO:WCB") Annotation( "UniProtKB:Q13291") "A SLAM family member 1 that is encoded in the genome of human.") +AnnotationAssertion( "UniProtKB:Q13291") +AnnotationAssertion(Annotation( "UniProtKB:Q13291") "CD150 (human)") +AnnotationAssertion(Annotation( "UniProtKB:Q13291") "CDw150 (human)") +AnnotationAssertion(Annotation( "UniProtKB:Q13291") "IPO-3 (human)") +AnnotationAssertion(Annotation( "UniProtKB:Q13291") "SLAM family member 1 (human)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hSLAMF1") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:Q13291") Annotation( ) "SLAM") +AnnotationAssertion(Annotation( "UniProtKB:Q13291") Annotation( ) "SLAMF1") +AnnotationAssertion( "PR:Q13291") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "signaling lymphocytic activation molecule (human)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (sonic hedgehog protein (human)) + +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( "UniProtKB:Q15465") "A sonic hedgehog protein that is encoded in the genome of human.") +AnnotationAssertion( "UniProtKB:Q15465") +AnnotationAssertion(Annotation( "UniProtKB:Q15465") "HHG-1 (human)") +AnnotationAssertion(Annotation( "UniProtKB:Q15465") "Shh unprocessed N-terminal signaling and C-terminal autoprocessing domains (human)") +AnnotationAssertion(Annotation( "UniProtKB:Q15465") "ShhNC (human)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hSHH") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:Q15465") Annotation( ) "SHH") +AnnotationAssertion( "PR:Q15465") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "sonic hedgehog protein (human)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (scavenger receptor cysteine-rich type 1 protein M130 (mouse)) + +AnnotationAssertion(Annotation( "OMA:Q2VLH6") Annotation( "PRO:DNx") "A scavenger receptor cysteine-rich type 1 protein M130 that is encoded in the genome of mouse.") +AnnotationAssertion( "UniProtKB:Q2VLH6") +AnnotationAssertion(Annotation( "UniProtKB:Q2VLH6") "CD163 (mouse)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mCD163") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:Q2VLH6") Annotation( ) "Cd163") +AnnotationAssertion(Annotation( "UniProtKB:Q2VLH6") Annotation( ) "M130") +AnnotationAssertion( "PR:Q2VLH6") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "scavenger receptor cysteine-rich type 1 protein M130 (mouse)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (neprilysin (mouse)) + +AnnotationAssertion(Annotation( "OMA:Q61391") Annotation( "PRO:DNx") "A neprilysin that is encoded in the genome of mouse.") +AnnotationAssertion( "UniProtKB:Q61391") +AnnotationAssertion(Annotation( "UniProtKB:Q61391") "CD10 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:Q61391") "NEP (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:Q61391") "SFE (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:Q61391") "atriopeptidase (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:Q61391") "enkephalinase (mouse)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mMME") +AnnotationAssertion(Annotation( "UniProtKB:Q61391") "neutral endopeptidase (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:Q61391") "neutral endopeptidase 24.11 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:Q61391") "skin fibroblast elastase (mouse)") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:Q61391") Annotation( ) "Mme") +AnnotationAssertion( "PR:Q61391") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "neprilysin (mouse)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (forkhead box protein N1 (mouse)) + +AnnotationAssertion(Annotation( "OMA:Q61575") Annotation( "PRO:DNx") "A forkhead box protein N1 that is encoded in the genome of mouse.") +AnnotationAssertion( "UniProtKB:Q61575") +AnnotationAssertion(Annotation( "UniProtKB:Q61575") "HFH-11 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:Q61575") "HNF-3/forkhead homolog 11 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:Q61575") "hepatocyte nuclear factor 3 forkhead homolog 11 (mouse)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mFOXN1") +AnnotationAssertion(Annotation( "UniProtKB:Q61575") "winged-helix transcription factor nude (mouse)") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:Q61575") Annotation( ) "Fkh19") +AnnotationAssertion(Annotation( "UniProtKB:Q61575") Annotation( ) "Foxn1") +AnnotationAssertion(Annotation( "UniProtKB:Q61575") Annotation( ) "Hfh11") +AnnotationAssertion(Annotation( "UniProtKB:Q61575") Annotation( ) "Whn") +AnnotationAssertion( "PR:Q61575") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "forkhead box protein N1 (mouse)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (sonic hedgehog protein (mouse)) + +AnnotationAssertion(Annotation( "OMA:Q62226") Annotation( "PRO:DNx") "A sonic hedgehog protein that is encoded in the genome of mouse.") +AnnotationAssertion( "UniProtKB:Q62226") +AnnotationAssertion(Annotation( "UniProtKB:Q62226") "HHG-1 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:Q62226") "SHH (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:Q62226") "Shh unprocessed N-terminal signaling and C-terminal autoprocessing domains (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:Q62226") "ShhNC (mouse)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mSHH") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:Q62226") Annotation( ) "Hhg1") +AnnotationAssertion(Annotation( "UniProtKB:Q62226") Annotation( ) "Shh") +AnnotationAssertion( "PR:Q62226") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "sonic hedgehog protein (mouse)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (transferrin receptor protein 1 (mouse)) + +AnnotationAssertion(Annotation( "OMA:Q62351") Annotation( "PRO:DNx") "A transferrin receptor protein 1 that is encoded in the genome of mouse.") +AnnotationAssertion( "UniProtKB:Q62351") +AnnotationAssertion(Annotation( "UniProtKB:Q62351") "CD71 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:Q62351") "TfR (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:Q62351") "TfR1 (mouse)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mTFRC") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:Q62351") "TR (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:Q62351") Annotation( ) "Tfrc") +AnnotationAssertion(Annotation( "UniProtKB:Q62351") Annotation( ) "Trfr") +AnnotationAssertion( "PR:Q62351") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "transferrin receptor protein 1 (mouse)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (endoglin (mouse)) + +AnnotationAssertion(Annotation( "OMA:Q63961") Annotation( "PRO:DNx") "An endoglin that is encoded in the genome of mouse.") +AnnotationAssertion( "UniProtKB:Q63961") +AnnotationAssertion(Annotation( "UniProtKB:Q63961") "CD105 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:Q63961") "cell surface MJ7/18 antigen (mouse)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mENG") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:Q63961") Annotation( ) "Edg") +AnnotationAssertion(Annotation( "UniProtKB:Q63961") Annotation( ) "Eng") +AnnotationAssertion( "PR:Q63961") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "endoglin (mouse)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (myeloid cell surface antigen CD33 (mouse)) + +AnnotationAssertion(Annotation( "PRO:WCB") "A CD33 molecule that is encoded in the genome of mouse.") +AnnotationAssertion( "UniProtKB:Q63994") +AnnotationAssertion(Annotation( "UniProtKB:Q63994") "CD33 (mouse)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mCD33") +AnnotationAssertion(Annotation( "UniProtKB:Q63994") "sialic acid-binding Ig-like lectin 3 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:Q63994") "siglec-3 (mouse)") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:Q63994") Annotation( ) "Cd33") +AnnotationAssertion(Annotation( "UniProtKB:Q63994") Annotation( ) "Siglec3") +AnnotationAssertion( "PR:Q63994") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "myeloid cell surface antigen CD33 (mouse)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (hematopoietic progenitor cell antigen CD34 (mouse)) + +AnnotationAssertion(Annotation( "OMA:Q64314") Annotation( "PRO:DNx") "A CD34 molecule that is encoded in the genome of mouse.") +AnnotationAssertion( "UniProtKB:Q64314") +AnnotationAssertion(Annotation( "UniProtKB:Q64314") "CD34 (mouse)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mCD34") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:Q64314") Annotation( ) "Cd34") +AnnotationAssertion( "PR:Q64314") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "hematopoietic progenitor cell antigen CD34 (mouse)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (lactosylceramide 4-alpha-galactosyltransferase (mouse)) + +AnnotationAssertion(Annotation( "OMA:Q67BJ4") Annotation( "PRO:DNx") "A lactosylceramide 4-alpha-galactosyltransferase that is encoded in the genome of mouse.") +AnnotationAssertion( "UniProtKB:Q67BJ4") +AnnotationAssertion(Annotation( "UniProtKB:Q67BJ4") "Gb3 synthase (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:Q67BJ4") "UDP-galactose:beta-D-galactosyl-beta1-R 4-alpha-D-galactosyltransferase (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:Q67BJ4") "alpha-1,4-galactosyltransferase (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:Q67BJ4") "alpha4Gal-T1 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:Q67BJ4") "globotriaosylceramide synthase (mouse)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mA4GALT") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:Q67BJ4") Annotation( ) "A4galt") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( "UniProtKB:Q67BJ4") "alpha-1,4-N-acetylglucosaminyltransferase (mouse)") +AnnotationAssertion( "PR:Q67BJ4") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "lactosylceramide 4-alpha-galactosyltransferase (mouse)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (scavenger receptor cysteine-rich type 1 protein M130 (human)) + +AnnotationAssertion(Annotation( "PRO:WCB") Annotation( "UniProtKB:Q86VB7") "A scavenger receptor cysteine-rich type 1 protein M130 that is encoded in the genome of human.") +AnnotationAssertion( "UniProtKB:Q86VB7") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hCD163") +AnnotationAssertion(Annotation( "UniProtKB:Q86VB7") "hemoglobin scavenger receptor (human)") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:Q86VB7") Annotation( ) "CD163") +AnnotationAssertion(Annotation( "UniProtKB:Q86VB7") Annotation( ) "M130") +AnnotationAssertion( "PR:Q86VB7") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "scavenger receptor cysteine-rich type 1 protein M130 (human)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (cadherin-5 (chicken)) + +AnnotationAssertion(Annotation( "OMA:Q8AYD0") Annotation( "PANTHER:PTHR24027:SF44") Annotation( "PRO:DNx") "A cadherin-5 that is encoded in the genome of chicken.") +AnnotationAssertion( "UniProtKB:Q8AYD0") +AnnotationAssertion(Annotation( "UniProtKB:Q8AYD0") "VE-cadherin (chicken)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "chick-CDH5") +AnnotationAssertion(Annotation( "UniProtKB:Q8AYD0") "vascular endothelial cadherin (chicken)") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:Q8AYD0") Annotation( ) "CDH5") +AnnotationAssertion( "PR:Q8AYD0") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "cadherin-5 (chicken)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (SCO-spondin (mouse)) + +AnnotationAssertion(Annotation( "PRO:DNx") "A SCO-spondin that is encoded in the genome of mouse.") +AnnotationAssertion( "UniProtKB:Q8CG65") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mSSPO") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:Q8CG65") Annotation( ) "Sspo") +AnnotationAssertion( "PR:Q8CG65") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "SCO-spondin (mouse)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (C-type lectin domain family 4 member K (mouse)) + +AnnotationAssertion(Annotation( "OMA:Q8VBX4") Annotation( "PRO:DNx") "A C-type lectin domain family 4 member K that is encoded in the genome of mouse.") +AnnotationAssertion( "UniProtKB:Q8VBX4") +AnnotationAssertion(Annotation( "UniProtKB:Q8VBX4") "CD207 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:Q8VBX4") "langerin (mouse)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mCD207") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:Q8VBX4") Annotation( ) "Cd207") +AnnotationAssertion(Annotation( "UniProtKB:Q8VBX4") Annotation( ) "Clec4k") +AnnotationAssertion( "PR:Q8VBX4") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "C-type lectin domain family 4 member K (mouse)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (spondin-1 (mouse)) + +AnnotationAssertion(Annotation( "OMA:Q8VCC9") Annotation( "PRO:DNx") "A spondin-1 that is encoded in the genome of mouse.") +AnnotationAssertion( "UniProtKB:Q8VCC9") +AnnotationAssertion(Annotation( "UniProtKB:Q8VCC9") "F-spondin (mouse)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mSPON1") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:Q8VCC9") Annotation( ) "Spon1") +AnnotationAssertion( "PR:Q8VCC9") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "spondin-1 (mouse)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (fibroblast growth factor 8 (chicken)) + +AnnotationAssertion(Annotation( "OMA:Q90722") Annotation( "PANTHER:PTHR11486:SF2") Annotation( "PRO:DNx") "A fibroblast growth factor 8 that is encoded in the genome of chicken.") +AnnotationAssertion( "UniProtKB:Q90722") +AnnotationAssertion(Annotation( "UniProtKB:Q90722") "FGF-8 (chicken)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "chick-FGF8") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:Q90722") Annotation( ) "FGF8") +AnnotationAssertion(Annotation( "UniProtKB:Q90722") "HBGF-8 (chicken)") +AnnotationAssertion(Annotation( "UniProtKB:Q90722") "heparin-binding growth factor 8 (chicken)") +AnnotationAssertion( "PR:Q90722") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "fibroblast growth factor 8 (chicken)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (transferrin receptor protein 1 (chicken)) + +AnnotationAssertion(Annotation( "PANTHER:PTHR10404:SF26") Annotation( "PRO:DNx") "A transferrin receptor protein 1 that is encoded in the genome of chicken.") +AnnotationAssertion( "UniProtKB:Q90997") +AnnotationAssertion(Annotation( "UniProtKB:Q90997") "TR (chicken)") +AnnotationAssertion(Annotation( "UniProtKB:Q90997") "TfR (chicken)") +AnnotationAssertion(Annotation( "UniProtKB:Q90997") "TfR1 (chicken)") +AnnotationAssertion(Annotation( "UniProtKB:Q90997") "Trfr (chicken)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "chick-TFRC") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:Q90997") Annotation( ) "TFRC") +AnnotationAssertion( "PR:Q90997") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "transferrin receptor protein 1 (chicken)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (sonic hedgehog protein (chicken)) + +AnnotationAssertion(Annotation( "PANTHER:PTHR11889:SF16") Annotation( "PRO:DNx") "A sonic hedgehog protein that is encoded in the genome of chicken.") +AnnotationAssertion( "UniProtKB:Q91035") +AnnotationAssertion(Annotation( "UniProtKB:Q91035") "Shh unprocessed N-terminal signaling and C-terminal autoprocessing domains (chicken)") +AnnotationAssertion(Annotation( "UniProtKB:Q91035") "ShhNC (chicken)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "chick-SHH") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:Q91035") Annotation( ) "SHH") +AnnotationAssertion( "PR:Q91035") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "sonic hedgehog protein (chicken)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (natural killer cell receptor 2B4 (human)) + +AnnotationAssertion(Annotation( "PRO:WCB") Annotation( "UniProtKB:Q9BZW8") "A natural killer cell receptor 2B4 that is encoded in the genome of human.") +AnnotationAssertion( "UniProtKB:Q9BZW8") +AnnotationAssertion(Annotation( "UniProtKB:Q9BZW8") "NAIL (human)") +AnnotationAssertion(Annotation( "UniProtKB:Q9BZW8") "NK cell activation-inducing ligand (human)") +AnnotationAssertion(Annotation( "UniProtKB:Q9BZW8") "NK cell type I receptor protein 2B4 (human)") +AnnotationAssertion(Annotation( "UniProtKB:Q9BZW8") "NKR2B4 (human)") +AnnotationAssertion(Annotation( "UniProtKB:Q9BZW8") "SLAM family member 4 (human)") +AnnotationAssertion(Annotation( "UniProtKB:Q9BZW8") "SLAMF4 (human)") +AnnotationAssertion(Annotation( "UniProtKB:Q9BZW8") "h2B4 (human)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hCD244") +AnnotationAssertion(Annotation( "UniProtKB:Q9BZW8") "signaling lymphocytic activation molecule 4 (human)") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:Q9BZW8") Annotation( ) "2B4") +AnnotationAssertion(Annotation( "UniProtKB:Q9BZW8") Annotation( ) "CD244") +AnnotationAssertion( "PR:Q9BZW8") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "natural killer cell receptor 2B4 (human)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (spondin-1 (human)) + +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( "UniProtKB:Q9HCB6") "A spondin-1 that is encoded in the genome of human.") +AnnotationAssertion( "UniProtKB:Q9HCB6") +AnnotationAssertion(Annotation( "UniProtKB:Q9HCB6") "F-spondin (human)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hSPON1") +AnnotationAssertion(Annotation( "UniProtKB:Q9HCB6") "vascular smooth muscle cell growth-promoting factor (human)") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:Q9HCB6") Annotation( ) "KIAA0762") +AnnotationAssertion(Annotation( "UniProtKB:Q9HCB6") Annotation( ) "SPON1") +AnnotationAssertion(Annotation( "UniProtKB:Q9HCB6") Annotation( ) "VSGP") +AnnotationAssertion( "PR:Q9HCB6") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "spondin-1 (human)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (lactosylceramide 4-alpha-galactosyltransferase (human)) + +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( "UniProtKB:Q9NPC4") "A lactosylceramide 4-alpha-galactosyltransferase that is encoded in the genome of human.") +AnnotationAssertion( "UniProtKB:Q9NPC4") +AnnotationAssertion(Annotation( "UniProtKB:Q9NPC4") "CD77 synthase (human)") +AnnotationAssertion(Annotation( "UniProtKB:Q9NPC4") "Gb3 synthase (human)") +AnnotationAssertion(Annotation( "UniProtKB:Q9NPC4") "P1/Pk synthase (human)") +AnnotationAssertion(Annotation( "UniProtKB:Q9NPC4") "UDP-galactose:beta-D-galactosyl-beta1-R 4-alpha-D-galactosyltransferase (human)") +AnnotationAssertion(Annotation( "UniProtKB:Q9NPC4") "alpha-1,4-galactosyltransferase (human)") +AnnotationAssertion(Annotation( "UniProtKB:Q9NPC4") "alpha4Gal-T1 (human)") +AnnotationAssertion(Annotation( "UniProtKB:Q9NPC4") "globotriaosylceramide synthase (human)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hA4GALT") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:Q9NPC4") Annotation( ) "A14GALT") +AnnotationAssertion(Annotation( "UniProtKB:Q9NPC4") Annotation( ) "A4GALT") +AnnotationAssertion(Annotation( "UniProtKB:Q9NPC4") Annotation( ) "A4GALT1") +AnnotationAssertion(Annotation( "UniProtKB:Q9NPC4") "alpha-1,4-N-acetylglucosaminyltransferase (human)") +AnnotationAssertion( "PR:Q9NPC4") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "lactosylceramide 4-alpha-galactosyltransferase (human)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (complement component C1q receptor (human)) + +AnnotationAssertion(Annotation( "PRO:WCB") Annotation( "UniProtKB:Q9NPY3") "A complement component C1q receptor that is encoded in the genome of human.") +AnnotationAssertion( "UniProtKB:Q9NPY3") +AnnotationAssertion(Annotation( "UniProtKB:Q9NPY3") "C1q/MBL/SPA receptor (human)") +AnnotationAssertion(Annotation( "UniProtKB:Q9NPY3") "C1qR (human)") +AnnotationAssertion(Annotation( "UniProtKB:Q9NPY3") "C1qR(p) (human)") +AnnotationAssertion(Annotation( "UniProtKB:Q9NPY3") "C1qRp (human)") +AnnotationAssertion(Annotation( "UniProtKB:Q9NPY3") "CDw93 (human)") +AnnotationAssertion(Annotation( "UniProtKB:Q9NPY3") "complement component 1 q subcomponent receptor 1 (human)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hCD93") +AnnotationAssertion(Annotation( "UniProtKB:Q9NPY3") "matrix-remodeling-associated protein 4 (human)") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:Q9NPY3") Annotation( ) "C1QR1") +AnnotationAssertion(Annotation( "UniProtKB:Q9NPY3") Annotation( ) "CD93") +AnnotationAssertion(Annotation( "UniProtKB:Q9NPY3") Annotation( ) "MXRA4") +AnnotationAssertion( "PR:Q9NPY3") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "complement component C1q receptor (human)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (integrin alpha-IIb (mouse)) + +AnnotationAssertion(Annotation( "OMA:Q9QUM0") Annotation( "PRO:DNx") "An integrin alpha-IIb that is encoded in the genome of mouse.") +AnnotationAssertion( "UniProtKB:Q9QUM0") +AnnotationAssertion(Annotation( "UniProtKB:Q9QUM0") "CD41 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:Q9QUM0") "GPIIb (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:Q9QUM0") "GPalpha IIb (mouse)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mITGA2B") +AnnotationAssertion(Annotation( "UniProtKB:Q9QUM0") "platelet membrane glycoprotein IIb (mouse)") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:Q9QUM0") Annotation( ) "Itga2b") +AnnotationAssertion( "PR:Q9QUM0") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "integrin alpha-IIb (mouse)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (signaling lymphocytic activation molecule (mouse)) + +AnnotationAssertion(Annotation( "OMA:Q9QUM4") Annotation( "PRO:DNx") "A SLAM family member 1 that is encoded in the genome of mouse.") +AnnotationAssertion( "UniProtKB:Q9QUM4") +AnnotationAssertion(Annotation( "UniProtKB:Q9QUM4") "CD150 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:Q9QUM4") "SLAM family member 1 (mouse)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mSLAMF1") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:Q9QUM4") Annotation( ) "Slam") +AnnotationAssertion(Annotation( "UniProtKB:Q9QUM4") Annotation( ) "Slamf1") +AnnotationAssertion( "PR:Q9QUM4") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "signaling lymphocytic activation molecule (mouse)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (integrin alpha-X (mouse)) + +AnnotationAssertion(Annotation( "OMA:Q9QXH4") Annotation( "PRO:DNx") "An integrin alpha-X that is encoded in the genome of mouse.") +AnnotationAssertion( "UniProtKB:Q9QXH4") +AnnotationAssertion(Annotation( "UniProtKB:Q9QXH4") "CD11 antigen-like family member C (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:Q9QXH4") "CD11c (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:Q9QXH4") "leukocyte adhesion glycoprotein p150,95 alpha chain (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:Q9QXH4") "leukocyte adhesion receptor p150,95 (mouse)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mITGAX") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:Q9QXH4") Annotation( ) "Itgax") +AnnotationAssertion( "PR:Q9QXH4") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "integrin alpha-X (mouse)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (C-type lectin domain family 4 member K (human)) + +AnnotationAssertion(Annotation( "PRO:WCB") Annotation( "UniProtKB:Q9UJ71") "A C-type lectin domain family 4 member K that is encoded in the genome of human.") +AnnotationAssertion(Annotation(rdfs:label "PR:Q9UJ71 located_in GO:0005886") "Reactome:R-HSA-1216519") +AnnotationAssertion(Annotation(rdfs:label "PR:Q9UJ71 located_in GO:0030669") "Reactome:R-HSA-1236762") +AnnotationAssertion(Annotation(rdfs:label "PR:Q9UJ71 located_in GO:0031901") "Reactome:R-HSA-1236852") +AnnotationAssertion( "UniProtKB:Q9UJ71") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hCD207") +AnnotationAssertion(Annotation( "UniProtKB:Q9UJ71") "langerin (human)") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:Q9UJ71") Annotation( ) "CD207") +AnnotationAssertion(Annotation( "UniProtKB:Q9UJ71") Annotation( ) "CLEC4K") +AnnotationAssertion( "PR:Q9UJ71") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "C-type lectin domain family 4 member K (human)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (Pax-5 protein (chicken)) + +AnnotationAssertion(Annotation( "OMA:Q9W601") Annotation( "PRO:DNx") "A paired box protein PAX-5 that is encoded in the genome of chicken.") +AnnotationAssertion( "UniProtKB:Q9W601") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "chick-PAX5") +AnnotationAssertion( "protein") +AnnotationAssertion( "PR:Q9W601") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "Pax-5 protein (chicken)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (spondin-1 (chicken)) + +AnnotationAssertion(Annotation( "PANTHER:PTHR11311:SF2") Annotation( "PRO:DNx") "A spondin-1 that is encoded in the genome of chicken.") +AnnotationAssertion( "UniProtKB:Q9W770") +AnnotationAssertion(Annotation( "UniProtKB:Q9W770") "F-spondin (chicken)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "chick-SPON1") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:Q9W770") Annotation( ) "SPON1") +AnnotationAssertion( "PR:Q9W770") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "spondin-1 (chicken)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (nuclear factor NF-kappa-B p100 subunit (mouse)) + +AnnotationAssertion(Annotation( "OMA:Q9WTK5") Annotation( "PRO:DNx") "A nuclear factor NF-kappa-B p100 subunit that is encoded in the genome of mouse.") +AnnotationAssertion( "UniProtKB:Q9WTK5") +AnnotationAssertion(Annotation( "UniProtKB:Q9WTK5") "DNA-binding factor KBF2 (mouse)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mNFKB2") +AnnotationAssertion(Annotation( "UniProtKB:Q9WTK5") "nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (mouse)") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:Q9WTK5") Annotation( ) "Nfkb2") +AnnotationAssertion( "PR:Q9WTK5") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "nuclear factor NF-kappa-B p100 subunit (mouse)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (tumor necrosis factor receptor superfamily member 11A (human)) + +AnnotationAssertion(Annotation( "PRO:WCB") Annotation( "UniProtKB:Q9Y6Q6") "A tumor necrosis factor receptor superfamily member 11A that is encoded in the genome of human.") +AnnotationAssertion( "UniProtKB:Q9Y6Q6") +AnnotationAssertion(Annotation( "UniProtKB:Q9Y6Q6") "CD265 (human)") +AnnotationAssertion(Annotation( "UniProtKB:Q9Y6Q6") "ODFR (human)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "hTNFRSF11A") +AnnotationAssertion(Annotation( "UniProtKB:Q9Y6Q6") "osteoclast differentiation factor receptor (human)") +AnnotationAssertion(Annotation( "UniProtKB:Q9Y6Q6") "receptor activator of NF-KB (human)") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:Q9Y6Q6") Annotation( ) "RANK") +AnnotationAssertion(Annotation( "UniProtKB:Q9Y6Q6") Annotation( ) "TNFRSF11A") +AnnotationAssertion( "PR:Q9Y6Q6") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "tumor necrosis factor receptor superfamily member 11A (human)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + +# Class: (CX3C chemokine receptor 1 (mouse)) + +AnnotationAssertion(Annotation( "OMA:Q9Z0D9") Annotation( "PRO:DNx") "A CX3C chemokine receptor 1 that is encoded in the genome of mouse.") +AnnotationAssertion( "UniProtKB:Q9Z0D9") +AnnotationAssertion(Annotation( "UniProtKB:Q9Z0D9") "C-X3-C CKR-1 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:Q9Z0D9") "CX3CR1 (mouse)") +AnnotationAssertion(Annotation( "UniProtKB:Q9Z0D9") "fractalkine receptor (mouse)") +AnnotationAssertion(Annotation( "PRO:DNx") Annotation( ) "mCX3CR1") +AnnotationAssertion( "protein") +AnnotationAssertion(Annotation( "UniProtKB:Q9Z0D9") Annotation( ) "Cx3cr1") +AnnotationAssertion( "PR:Q9Z0D9") +AnnotationAssertion(rdfs:comment "Category=organism-gene.") +AnnotationAssertion(rdfs:label "CX3C chemokine receptor 1 (mouse)") +EquivalentClasses( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +SubClassOf( ) +SubClassOf( ) +SubClassOf( ObjectSomeValuesFrom( )) + # Class: (system) AnnotationAssertion( "A material entity consisting of multiple components that are causally integrated.") @@ -62364,13 +150866,149 @@ AnnotationAssertion(rdfs:label "syst SubClassOf( ) +############################ +# Named Individuals +############################ + +# Individual: (example to be eventually removed) + +AnnotationAssertion( "example to be eventually removed"@en) +AnnotationAssertion(rdfs:label "example to be eventually removed"@en) + +# Individual: (failed exploratory term) + +AnnotationAssertion( "failed exploratory term"@en) +AnnotationAssertion( "The term was used in an attempt to structure part of the ontology but in retrospect failed to do a good job"@en) +AnnotationAssertion( "Person:Alan Ruttenberg"@en) +AnnotationAssertion(rdfs:label "failed exploratory term"@en) + +# Individual: (metadata complete) + +AnnotationAssertion( "metadata complete"@en) +AnnotationAssertion( "Class has all its metadata, but is either not guaranteed to be in its final location in the asserted IS_A hierarchy or refers to another class that is not complete."@en) +AnnotationAssertion(rdfs:label "metadata complete"@en) + +# Individual: (organizational term) + +AnnotationAssertion( "organizational term"@en) +AnnotationAssertion( "Term created to ease viewing/sort terms for development purpose, and will not be included in a release"@en) +AnnotationAssertion(rdfs:label "organizational term"@en) + +# Individual: (ready for release) + +AnnotationAssertion( "ready for release"@en) +AnnotationAssertion( "Class has undergone final review, is ready for use, and will be included in the next release. Any class lacking \"ready_for_release\" should be considered likely to change place in hierarchy, have its definition refined, or be obsoleted in the next release. Those classes deemed \"ready_for_release\" will also derived from a chain of ancestor classes that are also \"ready_for_release.\""@en) +AnnotationAssertion(rdfs:label "ready for release"@en) + +# Individual: (metadata incomplete) + +AnnotationAssertion( "metadata incomplete"@en) +AnnotationAssertion( "Class is being worked on; however, the metadata (including definition) are not complete or sufficiently clear to the branch editors."@en) +AnnotationAssertion(rdfs:label "metadata incomplete"@en) + +# Individual: (uncurated) + +AnnotationAssertion( "uncurated"@en) +AnnotationAssertion( "Nothing done yet beyond assigning a unique class ID and proposing a preferred term."@en) +AnnotationAssertion(rdfs:label "uncurated"@en) + +# Individual: (pending final vetting) + +AnnotationAssertion( "pending final vetting"@en) +AnnotationAssertion( "All definitions, placement in the asserted IS_A hierarchy and required minimal metadata are complete. The class is awaiting a final review by someone other than the term editor."@en) +AnnotationAssertion(rdfs:label "pending final vetting"@en) + +# Individual: (placeholder removed) + +AnnotationAssertion( "placeholder removed"@en) +AnnotationAssertion(rdfs:label "placeholder removed"@en) + +# Individual: (terms merged) + +AnnotationAssertion( "terms merged"@en) +AnnotationAssertion( "An editor note should explain what were the merged terms and the reason for the merge."@en) +AnnotationAssertion(rdfs:label "terms merged"@en) + +# Individual: (term imported) + +AnnotationAssertion( "term imported"@en) +AnnotationAssertion( "This is to be used when the original term has been replaced by a term imported from an other ontology. An editor note should indicate what is the URI of the new term to use."@en) +AnnotationAssertion(rdfs:label "term imported"@en) + +# Individual: (term split) + +AnnotationAssertion( "term split"@en) +AnnotationAssertion( "This is to be used when a term has been split in two or more new terms. An editor note should indicate the reason for the split and indicate the URIs of the new terms created."@en) +AnnotationAssertion(rdfs:label "term split"@en) + +# Individual: (universal) + +AnnotationAssertion( "universal"@en) +AnnotationAssertion( "Hard to give a definition for. Intuitively a \"natural kind\" rather than a collection of any old things, which a class is able to be, formally. At the meta level, universals are defined as positives, are disjoint with their siblings, have single asserted parents."@en) +AnnotationAssertion( "Alan Ruttenberg"@en) +AnnotationAssertion( "A Formal Theory of Substances, Qualities, and Universals, http://ontology.buffalo.edu/bfo/SQU.pdf"@en) +AnnotationAssertion(rdfs:label "universal"@en) + +# Individual: (defined class) + +AnnotationAssertion( "defined class"@en) +AnnotationAssertion( "A defined class is a class that is defined by a set of logically necessary and sufficient conditions but is not a universal"@en) +AnnotationAssertion( "\"definitions\", in some readings, always are given by necessary and sufficient conditions. So one must be careful (and this is difficult sometimes) to distinguish between defined classes and universal."@en) +AnnotationAssertion( "Alan Ruttenberg"@en) +AnnotationAssertion(rdfs:label "defined class"@en) + +# Individual: (named class expression) + +AnnotationAssertion( "named class expression"@en) +AnnotationAssertion( "A named class expression is a logical expression that is given a name. The name can be used in place of the expression."@en) +AnnotationAssertion( "named class expressions are used in order to have more concise logical definition but their extensions may not be interesting classes on their own. In languages such as OWL, with no provisions for macros, these show up as actuall classes. Tools may with to not show them as such, and to replace uses of the macros with their expansions"@en) +AnnotationAssertion( "Alan Ruttenberg"@en) +AnnotationAssertion(rdfs:label "named class expression"@en) + +# Individual: (to be replaced with external ontology term) + +AnnotationAssertion( "to be replaced with external ontology term"@en) +AnnotationAssertion( "Terms with this status should eventually replaced with a term from another ontology."@en) +AnnotationAssertion( "Alan Ruttenberg"@en) +AnnotationAssertion( "group:OBI"@en) +AnnotationAssertion(rdfs:label "to be replaced with external ontology term"@en) + +# Individual: (requires discussion) + +AnnotationAssertion( "requires discussion"@en) +AnnotationAssertion( "A term that is metadata complete, has been reviewed, and problems have been identified that require discussion before release. Such a term requires editor note(s) to identify the outstanding issues."@en) +AnnotationAssertion( "Alan Ruttenberg"@en) +AnnotationAssertion( "group:OBI"@en) +AnnotationAssertion(rdfs:label "requires discussion"@en) + +# Individual: (out of scope) + +AnnotationAssertion( "The term was added to the ontology on the assumption it was in scope, but it turned out later that it was not."@en) +AnnotationAssertion( "This obsolesence reason should be used conservatively. Typical valid examples are: un-necessary grouping classes in disease ontologies, a phenotype term added on the assumption it was a disease."@en) +AnnotationAssertion( ) +AnnotationAssertion( "https://github.com/information-artifact-ontology/ontology-metadata/issues/77") +AnnotationAssertion( "https://orcid.org/0000-0001-5208-3432") +AnnotationAssertion(rdfs:label "out of scope") + + +EquivalentClasses(ObjectIntersectionOf( ObjectSomeValuesFrom( )) ObjectIntersectionOf( ObjectMinCardinality(2 ))) +EquivalentClasses(ObjectIntersectionOf( ObjectComplementOf(ObjectSomeValuesFrom( ))) ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +EquivalentClasses(ObjectIntersectionOf( ObjectSomeValuesFrom( )) ObjectIntersectionOf( ObjectSomeValuesFrom( ))) +EquivalentClasses(ObjectIntersectionOf( ObjectSomeValuesFrom( )) ObjectIntersectionOf( ObjectExactCardinality(2 ))) +EquivalentClasses(ObjectIntersectionOf( ObjectSomeValuesFrom( )) ObjectIntersectionOf( ObjectExactCardinality(1 ))) +EquivalentClasses(ObjectIntersectionOf( ObjectSomeValuesFrom( )) ObjectIntersectionOf( ObjectMinCardinality(2 ))) +SubClassOf(ObjectIntersectionOf( ObjectSomeValuesFrom( )) ObjectSomeValuesFrom( )) +SubClassOf(ObjectIntersectionOf( ObjectSomeValuesFrom( )) ObjectSomeValuesFrom( )) SubClassOf(ObjectIntersectionOf( ObjectSomeValuesFrom( )) ) SubClassOf(ObjectIntersectionOf( ObjectSomeValuesFrom( )) ) SubClassOf(ObjectIntersectionOf( ObjectSomeValuesFrom( )) ) SubClassOf(Annotation( ) ObjectIntersectionOf( ObjectSomeValuesFrom( )) ObjectSomeValuesFrom( )) +SubClassOf(ObjectSomeValuesFrom( ) ) SubClassOf(ObjectSomeValuesFrom( ) ObjectUnionOf(ObjectSomeValuesFrom( ObjectSomeValuesFrom( )) ObjectSomeValuesFrom( ObjectSomeValuesFrom( ObjectSomeValuesFrom( ))))) DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )) DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )) +DisjointClasses(ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )) SubObjectPropertyOf(ObjectPropertyChain( ) ) SubObjectPropertyOf(ObjectPropertyChain( ) ) SubObjectPropertyOf(ObjectPropertyChain( ) ) @@ -62398,6 +151036,8 @@ SubObjectPropertyOf(ObjectPropertyChain( ) ) SubObjectPropertyOf(ObjectPropertyChain( ) ) SubObjectPropertyOf(ObjectPropertyChain( ) ) +SubObjectPropertyOf(ObjectPropertyChain( ) ) +SubObjectPropertyOf(ObjectPropertyChain( ) ) SubObjectPropertyOf(ObjectPropertyChain( ) ) SubObjectPropertyOf(ObjectPropertyChain( ) ) SubObjectPropertyOf(ObjectPropertyChain( ) ) @@ -62450,6 +151090,8 @@ SubObjectPropertyOf(ObjectPropertyChain( ) ) SubObjectPropertyOf(ObjectPropertyChain( ) ) SubObjectPropertyOf(ObjectPropertyChain( ) ) +SubObjectPropertyOf(ObjectPropertyChain( ) ) +SubObjectPropertyOf(ObjectPropertyChain( ) ) SubObjectPropertyOf(Annotation( "true"^^xsd:boolean) ObjectPropertyChain( ) ) SubObjectPropertyOf(ObjectPropertyChain( ) ) SubObjectPropertyOf(ObjectPropertyChain( ) ) @@ -62499,9 +151141,6 @@ DLSafeRule(Body(ObjectPropertyAtom( V DLSafeRule(Body(ObjectPropertyAtom( Variable() Variable()) ObjectPropertyAtom( Variable() Variable()))Head(ObjectPropertyAtom( Variable() Variable()))) DLSafeRule(Body(ObjectPropertyAtom( Variable() Variable()) ObjectPropertyAtom( Variable() Variable()))Head(ObjectPropertyAtom( Variable() Variable()))) DLSafeRule(Body(ObjectPropertyAtom( Variable() Variable()) ObjectPropertyAtom( Variable() Variable()))Head(ObjectPropertyAtom( Variable() Variable()))) -AnnotationAssertion( "terms merged"@en) -AnnotationAssertion( "An editor note should explain what were the merged terms and the reason for the merge."@en) -AnnotationAssertion(rdfs:label "terms merged"@en) AnnotationAssertion(Annotation( ) "researcher") AnnotationAssertion(Annotation( ) rdfs:label "Nicole Vasilevsky") AnnotationAssertion(Annotation( ) "German-Moroccan paleontologist and anatomist") diff --git a/src/ontology/imports/omo_terms.txt b/src/ontology/imports/omo_terms.txt index d3f1423d84..fd22180454 100644 --- a/src/ontology/imports/omo_terms.txt +++ b/src/ontology/imports/omo_terms.txt @@ -1,3 +1,5 @@ OMO:0003004 OMO:0003000 +OMO:0003011 +